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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6e6636c4e26b2603bcd2d228ad7c04447ac2825d55797983024905c433ec8e70
+size 65712

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2859,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.4150943396226414
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C184/C184_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,8 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9919467787114846	2.209667761838324	0.0271282287119292	0.7672193300315866	0.4466216903000831	3	Q9HB40,Q9H3G5	2
+Cysteine peptidase, asparagine active site [IPR025661]	0.9716485824291216	1.463405803093469	0.143356371718097	0.9997255836305532	0.4851388857929413	2	Q9UBR2	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.6395167290616302	1.2874144055951957	0.1979498859115924	0.9999916308806468	0.4851388857929413	5	Q9Y217,P18031,Q06124	3
+Cysteine peptidase, cysteine active site [IPR000169]	0.7046585249333943	1.2059351812678774	0.2278424841446316	0.9999988820745036	0.5031521524860614	4	P53634	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.4322658950450945	0.4044333925248213	0.6858940489122187	1.0	0.93211242544481	5	P68036	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.4988524375036788	0.290468737806363	0.7714576639055917	1.0	0.9735060996903896	38	Q00534,Q8TD19,Q13546,O14965,Q14012,Q96KB5,O14757,Q99570,Q00535,O14976,P49841,Q86Y07,Q99640,P50613,P11802,P50750	16
+Nucleoside diphosphate kinase, active site [IPR023005]	0.4077703885194256	0.0336596185387831	0.9731485804495486	1.0	0.979081562830119	2	P15531	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CHEK1", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "CTSZ", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAPK3", "MDH1", "MDH2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SEC11C", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["AURKA", "CAMK1", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CHEK1", "CPVL", "CTSC", "CTSZ", "GAK", "GSK3B", "MTMR6", "NEK9", "NME1", "PBK", "PIK3R4", "PKMYT1", "PTPN1", "PTPN11", "RIPK1", "SCPEP1", "UBE2L3", "VRK2"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:dd6422ff58429eb8c55216084b6c53af71024a689a42146916de4202eda36cbf
+size 63878

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2859,
+    "annotations_size": 30,
+    "title": "Average number of proteins per term",
+    "value": 4.3
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C184/C184_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.8760938046902343	1.099094927460005	0.2717266622509502	0.9999260680231598	0.7836291691920606	2	Q9H0C8	1
+Peptidase M16, zinc-binding site [IPR001431]	0.4940944773571052	0.6491907679276793	0.5162150782379626	0.9999999996536064	0.9565932866311642	5	O43847	1
+Beta tubulin, autoregulation binding site [IPR013838]	0.4527356375228639	0.4819814751803068	0.6298191060149054	0.9999999999998872	0.9565932866311642	5	P04350,Q9BUF5,P07437	3
+Protein kinase, ATP binding site [IPR017441]	0.4362800268009199	0.1537765428027489	0.8777859299496422	1.0	0.9565932866311642	32	Q00534,P41240,P19784,O14965,Q14012,P19525,O14757,Q16513,Q00535,Q13464,P49841,Q99640,P50613,P11802,Q96SB4,P50750	16

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CETN2", "CHEK1", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AURKA", "CAMK1", "CDK4", "CDK5", "CDK6", "CDK7", "CDK9", "CHEK1", "CSK", "CSNK2A2", "EIF2AK2", "GSK3B", "ILKAP", "NRDC", "PKMYT1", "PKN2", "ROCK1", "SRPK1", "TUBB", "TUBB4A", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Ubiquitin specific protease, conserved site [IPR018200]", "1": "Cullin, conserved site [IPR016157]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:91638cb4fe61b7eb83a5f814e23404e5b7b1cb38cd858044e14b09b29b6053d8
+size 70257

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2859,
+    "annotations_size": 265,
+    "title": "Average number of proteins per term",
+    "value": 2.611320754716981
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C184/C184_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,39 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tetraspanin, conserved site [IPR018503]	0.9880994049702488	1.5265321217365433	0.1268773970508259	0.9999999999999998	0.6856604015068386	2	O60637	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.6872855585670118	1.5216608767095778	0.1280940753533395	0.9999999999999998	0.6856604015068386	10	P38398,Q14527,Q99496,Q99590	4
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.9754987749387468	1.478179579757734	0.1393597180915762	1.0	0.6856604015068386	2	P13473	1
+C-type lectin, conserved site [IPR018378]	0.975148757437872	1.476836469552235	0.1397194780429029	1.0	0.6856604015068386	2	Q5KU26	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9695484774238712	1.4553479101903977	0.1455729692899507	1.0	0.6882033806706109	2	P04066	1
+Kinesin motor domain, conserved site [IPR019821]	0.666977926382569	1.4465298292998616	0.1480286516914144	1.0	0.6882033806706109	9	P52732,O95239,Q99661,Q9Y496	4
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6909018681383778	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6909018681383778	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6909018681383778	2	P05067	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.9404970248512424	1.343980084201039	0.178954827152924	1.0	0.7137650942991963	2	P01889	1
+Guanylate kinase, conserved site [IPR020590]	0.550057881101236	0.9570904377622051	0.3385216096091472	1.0	0.9074602616177564	6	Q00013	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.5488137133678906	0.900242315027453	0.3679913118457429	1.0	0.9199782796143574	9	Q86UV5,P51784,Q9Y4E8,Q96K76,Q14694	5
+Mrp, conserved site [IPR000808]	0.8204410220511025	0.8927417636173538	0.3719954795233675	1.0	0.921297215641985	2	Q8TB37	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6341329954441443	0.8100775799178058	0.4178955890333535	1.0	0.9351038734909743	3	O15347	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.5198656540077493	0.7585126875435806	0.4481441205032217	1.0	0.9351038734909743	5	Q9H4L5,P22059	2
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.7584879243962197	0.6744242981269736	0.5000415991865905	1.0	0.988888237197362	2	P09884	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.7500875043752185	0.6461571542491165	0.5181775841573291	1.0	0.9921303210322456	2	O94813	1
+EGF-like, conserved site [IPR013032]	0.7500875043752185	0.6461571542491165	0.5181775841573291	1.0	0.9921303210322456	2	O94813	1
+Sterol reductase, conserved site [IPR018083]	0.719985999299965	0.5482448013600755	0.5835238234040685	1.0	1.0	2	Q14739	1
+Methylthiotransferase, conserved site [IPR020612]	0.7028351417570877	0.4951414859630754	0.6205002512782238	1.0	1.0	2	Q96SZ6	1
+Tubulin, conserved site [IPR017975]	0.4527356375228639	0.4819814751803068	0.6298191060149054	1.0	1.0	5	P04350,Q9BUF5,P07437	3
+Phosphofructokinase, conserved site [IPR015912]	0.517507002801122	0.4041207808526265	0.6861239043129874	1.0	1.0	3	P08237,Q01813	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6611830591529575	0.3758882289871645	0.7069999917981344	1.0	1.0	2	P10644	1
+DnaJ domain, conserved site [IPR018253]	0.4165311352636694	0.32352090062414	0.7463007814644294	1.0	1.0	10	Q9Y2G8	1
+S100/Calbindin-D9k, conserved site [IPR001751]	0.6111305565278263	0.2542878225705201	0.7992732068589792	1.0	1.0	2	P31949	1
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.6100805040252013	0.2520209279068041	0.8010248876578643	1.0	1.0	2	Q13126	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.6083304165208259	0.2482699744756137	0.8039255287546294	1.0	1.0	2	P14174	1
+4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]	0.4338235294117665	0.1882069519215462	0.8507144230282997	1.0	1.0	3	O00217,P61221	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.4026284983809978	0.173405537769328	0.8623326725364111	1.0	1.0	4	O43175	1
+Malic enzyme, conserved site [IPR015884]	0.5327266363318164	0.1196426950237506	0.9047661968821892	1.0	1.0	2	P48163	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.4739236961848092	0.0629966123094434	0.9497692019501768	1.0	1.0	2	Q9UBT2	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.4340217010850541	0.041944268297049	0.9665431264327636	1.0	1.0	2	P06737	1
+Histidine triad, conserved site [IPR019808]	0.4287714385719284	0.0399851590150156	0.9681049582213102	1.0	1.0	2	Q96C86	1
+Cullin, conserved site [IPR016157]	0.3042411496670206	0.0382699278727275	0.9694724672956568	1.0	1.0	6	Q13618,Q13620,Q13619,Q13617,Q13616	5
+Ras GTPase-activating protein, conserved site [IPR023152]	0.3133753501400583	0.0369059562014857	0.970559990622341	1.0	1.0	3	Q86VI3,P46940	2
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	1.0	2	Q9H9Y6	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.3012460968427738	0.0202505470550563	0.9838435054195922	1.0	1.0	8	Q13277	1
+DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]	0.3097964867048206	0.0007563051383645	0.9993965558643711	1.0	1.0	14	Q92620,P18074,Q9UNY4,Q9H6R0	4

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MOCS1", "MPI", "MPP1", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC11C", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRM", "STAM", "STMN1", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "UIMC1", "USP10", "USP11", "USP14", "USP15", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCE1", "APP", "BRCA1", "CDK5RAP1", "COLEC12", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "DCPS", "DHX33", "DHX38", "DNAJC16", "ERCC2", "FUCA1", "HLA-B", "HLTF", "HMGB3", "IQGAP1", "IQGAP3", "KIF11", "KIF2C", "KIF3A", "KIF4A", "LAMP2", "LBR", "ME1", "MIF", "MPP1", "MTAP", "NDUFS8", "NUBPL", "OSBP", "OSBPL3", "PFKM", "PFKP", "PHGDH", "POLA1", "POLR1B", "PRKAR1A", "PYGL", "RNF2", "S100A11", "SCAF11", "SLIT2", "STX3", "TSPAN3", "TTF2", "TUBB", "TUBB4A", "TUBB6", "UBA2", "USP10", "USP11", "USP15", "USP47", "USP48"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Immunoglobulin-like domain [IPR007110]", "1": "Zinc finger, RING-type [IPR001841]", "2": "Glutathione S-transferase, C-terminal [IPR004046]", "3": "Pleckstrin homology domain [IPR001849]", "4": "Importin-beta, N-terminal domain [IPR001494]", "5": "Ubiquitin specific protease domain [IPR028889]", "6": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "7": "Zinc finger C2H2-type [IPR013087]", "8": "Phosphoribosyltransferase domain [IPR000836]", "9": "PDZ domain [IPR001478]", "10": "Protein kinase domain [IPR000719]", "11": "W2 domain [IPR003307]", "12": "Cullin protein, neddylation domain [IPR019559]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:4a6ce6f311a1200670575ebb6632f969115f931dbc1c96c660866c0a277db5b5
+size 109770

interpro_domain/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]	1	5	2.091912014368046	0.0364463871476181	3.1310679611650487	7.058252427184466	-0.7432667795021679	0.3821273855973903	1.7424750350603202	1.1000903998021376	1.0328033817114417	0.3009059207517989	1.0	0.0937235599037543	0.0158256043387446	0.0846217526668656	0.255405515221392

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2859,
+    "annotations_size": 2413,
+    "title": "Average number of proteins per term",
+    "value": 2.107749689183589
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C184/C184_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,261 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+BTB/POZ domain [IPR000210]	0.9416589843042502	2.122421227658222	0.0338023811571339	1.0	0.6768203072490807	4	Q08380	1
+Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]	0.8245801626404113	2.091912014368046	0.0364463871476181	1.0	0.6768203072490807	5	P62140	1
+Immunoglobulin C1-set [IPR003597]	0.940826330532213	2.014899498632241	0.0439151805539723	1.0	0.6768203072490807	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.940826330532213	2.014899498632241	0.0439151805539723	1.0	0.6768203072490807	3	P10321,P01889	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.940826330532213	2.014899498632241	0.0439151805539723	1.0	0.6768203072490807	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.940826330532213	2.014899498632241	0.0439151805539723	1.0	0.6768203072490807	3	P10321,P01889	2
+Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]	0.9117288261958354	2.010228251984633	0.0444070365623656	1.0	0.6768203072490807	4	P62140	1
+Fibronectin type II domain [IPR000562]	0.9170168067226894	1.9230314073805128	0.0544761056157621	1.0	0.6768203072490807	3	Q9UBG0,P11717	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7833063954100974	1.917200662328229	0.0552124439653753	1.0	0.6768203072490807	5	Q9UIQ6,P55786	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7833063954100974	1.917200662328229	0.0552124439653753	1.0	0.6768203072490807	5	Q9UIQ6,P55786	2
+Rab-GTPase-TBC domain [IPR000195]	0.876797257880449	1.766329369576741	0.0773406070482445	1.0	0.6768203072490807	3	Q8TC07	1
+Immunoglobulin-like domain [IPR007110]	0.7413783024351085	1.7307084508739423	0.0835037772224898	1.0	0.6768203072490807	12	Q08722,Q92859,P04439,Q9Y639,P10321,P01889,Q8WX93	7
+Death domain [IPR000488]	0.8665987833685043	1.7263185966100152	0.0842901115466365	1.0	0.6768203072490807	3	Q13546	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.8651349491924998	1.7205672663073404	0.085329377634066	1.0	0.6768203072490807	3	O00203	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.7374259304874109	1.719428779682337	0.0855363255796621	1.0	0.6768203072490807	5	Q99956,P18031	2
+PPM-type phosphatase domain [IPR001932]	0.8639842399959904	1.7160447455555392	0.0861538530727312	1.0	0.6768203072490807	3	Q9H0C8	1
+FYVE zinc finger [IPR000306]	0.8629834843712161	1.712110548215156	0.0868762978382329	1.0	0.6768203072490807	3	Q7Z3T8	1
+Zinc finger, FYVE-related [IPR017455]	0.8629834843712161	1.712110548215156	0.0868762978382329	1.0	0.6768203072490807	3	Q7Z3T8	1
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.8613445378151264	1.705665435600639	0.0880703885629974	1.0	0.6768203072490807	3	Q9Y4E8,P51784	2
+Sec24-like, trunk domain [IPR041742]	0.8494494408565993	1.658814790284557	0.0971531190648229	1.0	0.6768203072490807	3	O95487	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.8484481477265601	1.65486535656288	0.0979518129525391	1.0	0.6768203072490807	3	P51784	1
+Ubiquitin system component CUE [IPR003892]	0.8397774585323947	1.6206304327149188	0.1050969214415094	1.0	0.6768203072490807	3	Q9H1I8	1
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.6890472335675839	1.6024477151627996	0.1090566406328756	1.0	0.6768203072490807	6	Q9UJY4	1
+Tudor domain [IPR002999]	0.6906136475210295	1.5730311080412511	0.1157116152962007	1.0	0.6768203072490807	8	Q16637,Q15047,Q9Y2W6,Q92667	4
+MD-2-related lipid-recognition domain [IPR003172]	0.990549527476374	1.535933174958268	0.1245547706487042	1.0	0.6768203072490807	2	P61916	1
+Rhodanese-like domain [IPR001763]	0.8168473444612694	1.5298239130229392	0.126060320830541	1.0	0.6768203072490807	3	Q99956	1
+ERAP1-like C-terminal domain [IPR024571]	0.8129787258423328	1.5144701383246597	0.1299066420004067	1.0	0.6768203072490807	3	Q9UIQ6	1
+PA domain [IPR003137]	0.984249212460623	1.5117581395522313	0.1305954021111621	1.0	0.6768203072490807	2	Q8TCT8	1
+Peptidase M28 [IPR007484]	0.8113753044677827	1.5081040274021118	0.1315279046274029	1.0	0.6768203072490807	3	P02786	1
+BTB/Kelch-associated [IPR011705]	0.9807490374518726	1.498326708347135	0.1340483881693437	1.0	0.6768203072490807	2	Q08380	1
+Serine-threonine protein phosphatase, N-terminal [IPR031675]	0.9796989849492476	1.494297246387618	0.1350979445465223	1.0	0.6768203072490807	2	P62140	1
+Immunoglobulin subtype [IPR003599]	0.6721669589019341	1.4884549551123416	0.1366309529981384	1.0	0.6768203072490807	8	Q92859,Q8WX93,Q9Y639	3
+Immunoglobulin subtype 2 [IPR003598]	0.672166958901934	1.4884549551123398	0.1366309529981388	1.0	0.6768203072490807	8	Q92859,Q8WX93,Q9Y639	3
+WWE domain [IPR004170]	0.803508388368916	1.4768506182191523	0.1397156845180407	1.0	0.6768203072490807	3	Q7Z2W4	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.975148757437872	1.476836469552235	0.1397194780429029	1.0	0.6768203072490807	2	Q5KU26	1
+C-type lectin-like [IPR001304]	0.975148757437872	1.476836469552235	0.1397194780429029	1.0	0.6768203072490807	2	Q5KU26	1
+BRICHOS domain [IPR007084]	0.9740987049352468	1.4728071799831937	0.1408030357599816	1.0	0.6768203072490807	2	Q9NQX7	1
+Peptidase C1A, papain C-terminal [IPR000668]	0.9716485824291216	1.463405803093469	0.143356371718097	1.0	0.6768203072490807	2	Q9UBR2	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9695484774238712	1.4553479101903977	0.1455729692899507	1.0	0.6768203072490807	2	P04066	1
+Kinesin motor domain [IPR001752]	0.666977926382569	1.4465298292998616	0.1480286516914144	1.0	0.6768203072490807	9	P52732,O95239,Q99661,Q9Y496	4
+Zinc finger, ZZ-type [IPR000433]	0.7951680672268913	1.443685931257127	0.1488273406340456	1.0	0.6768203072490807	3	Q8IYH5,Q13501	2
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.9565978298914946	1.4056727601164638	0.1598213192767414	1.0	0.6768203072490807	2	P06865	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.9565978298914946	1.4056727601164638	0.1598213192767414	1.0	0.6768203072490807	2	P06865	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9527476373818692	1.3909119051629992	0.1642521422366709	1.0	0.6768203072490807	2	P05067	1
+EXPERA domain [IPR033118]	0.9513475673783688	1.3855454378524137	0.1658857487789868	1.0	0.6768203072490807	2	Q15125	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9506475323766188	1.3828624458403145	0.1667070471924323	1.0	0.6768203072490807	2	Q8IV08	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.7777946017668753	1.37452905163549	0.1692774975265081	1.0	0.6768203072490807	3	Q06323	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.7777946017668753	1.37452905163549	0.1692774975265081	1.0	0.6768203072490807	3	Q06323	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.7748599439775917	1.3628411696254048	0.1729325729601489	1.0	0.6768203072490807	3	Q06124,P18031	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6399210989708355	1.3576314431037393	0.1745806605308693	1.0	0.6768203072490807	7	O00429	1
+Dynamin, N-terminal [IPR045063]	0.6399210989708355	1.3576314431037393	0.1745806605308693	1.0	0.6768203072490807	7	O00429	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.742068953692073	1.3535909289268184	0.1758669225195182	1.0	0.6768203072490807	4	O95487	1
+Sec23/Sec24, trunk domain [IPR006896]	0.742068953692073	1.3535909289268184	0.1758669225195182	1.0	0.6768203072490807	4	O95487	1
+Sec23/Sec24 beta-sandwich [IPR012990]	0.742068953692073	1.3535909289268184	0.1758669225195182	1.0	0.6768203072490807	4	O95487	1
+Sec23/Sec24, helical domain [IPR006900]	0.742068953692073	1.3535909289268184	0.1758669225195182	1.0	0.6768203072490807	4	O95487	1
+Gelsolin-like domain [IPR007123]	0.6524124569158299	1.344855907975187	0.1786717714527457	1.0	0.6821756084105624	5	O95487,O95486	2
+Formin, FH2 domain [IPR015425]	0.6515343744819103	1.340947750572957	0.1799374172548327	1.0	0.6837621855683643	5	O60879,Q9NSV4	2
+Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]	0.6515343744819103	1.340947750572957	0.1799374172548327	1.0	0.6837621855683643	5	O60879,Q9NSV4	2
+Post-SET domain [IPR003616]	0.7621334456045439	1.3121494012840609	0.1894697303524917	1.0	0.7066313127365725	3	Q15047	1
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.7611834572655731	1.308365578572647	0.1907493418674448	1.0	0.7084310874099609	3	Q9NSV4	1
+Ras-associating (RA) domain [IPR000159]	0.7507002801120457	1.2666195665860764	0.2052913526585289	1.0	0.7255137203864832	3	Q15036,Q9Y4G8	2
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.7469923884536226	1.2518600119512462	0.2106208780257112	1.0	0.7323172603401172	3	Q9NRG0	1
+Zinc finger, RING-type [IPR001841]	0.6683317704103273	1.2444805355724822	0.2133227587143045	1.0	0.7330608272341452	21	Q99496,Q96T51,Q8TDB6,P38398,Q9Y4X5,Q99590,Q86UK7,Q9UKV5,Q14527	9
+Ubiquitin-like domain, USP-type [IPR028135]	0.912495624781239	1.237018953283454	0.2160800462772563	1.0	0.7364423046144343	2	P51784	1
+Immunoglobulin V-set domain [IPR013106]	0.7415615749239013	1.230250626379361	0.218603267046932	1.0	0.7420739960460795	3	P78310	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.905495274763738	1.2103755614826408	0.226134815062093	1.0	0.7517687945618443	2	Q13641	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.905495274763738	1.2103755614826408	0.226134815062093	1.0	0.7517687945618443	2	Q13641	1
+Elp3/MiaB/NifB [IPR006638]	0.7005454421308339	1.189701942499785	0.2341635616398674	1.0	0.7517687945618443	4	Q9H9T3,Q96SZ6	2
+Radical SAM [IPR007197]	0.7005454421308339	1.189701942499785	0.2341635616398674	1.0	0.7517687945618443	4	Q9H9T3,Q96SZ6	2
+Glutamine amidotransferase [IPR017926]	0.6903677758318767	1.1495549885265464	0.2503272061810389	1.0	0.78142244309812	4	P27708,P49915,P17812	3
+Glutamine amidotransferase type 2 domain [IPR017932]	0.7209768084446486	1.1484827382585712	0.2507693349896396	1.0	0.7817659115808822	3	P08243	1
+Formin, GTPase-binding domain [IPR010473]	0.6827834852432793	1.1196671843513153	0.2628556140117011	1.0	0.789174033972549	4	O60879,Q9NSV4	2
+Formin, FH3 domain [IPR010472]	0.6827834852432793	1.1196671843513153	0.2628556140117011	1.0	0.789174033972549	4	O60879,Q9NSV4	2
+Cyclic nucleotide-binding domain [IPR000595]	0.6017185354941212	1.1188046220038166	0.2632234994515539	1.0	0.789174033972549	5	Q9Y4G8	1
+CAP Gly-rich domain [IPR000938]	0.7120348628339939	1.113062628559613	0.2656815325983017	1.0	0.7895191356646578	3	Q99426	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.5930174249105338	1.104297864097438	0.2694639490641812	1.0	0.7949815353889998	9	P21266,P28161,P26641,O43324,Q13155	5
+La-type HTH domain [IPR006630]	0.5767824125475877	1.0078451898357397	0.3135287877463439	1.0	0.8127650078024256	5	Q6PKG0,Q71RC2,Q92615	3
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.8473923696184809	0.9917979522903064	0.3212960967723086	1.0	0.8127650078024256	2	P18031	1
+NIPSNAP [IPR012577]	0.8442422121106055	0.9801248294200632	0.3270245042532065	1.0	0.8160394299513829	2	O75323	1
+Ataxin-2, C-terminal [IPR009818]	0.8435421771088554	0.9775339418293684	0.3283048826652768	1.0	0.8171622544750421	2	Q14694	1
+PITH domain [IPR010400]	0.8431921596079802	0.9762389328848232	0.3289460740404095	1.0	0.8171622544750421	2	Q9GZP4	1
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.6741669271791267	0.9641923571011818	0.3349494954751928	1.0	0.821593340021185	3	P09884	1
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.6741669271791267	0.9641923571011818	0.3349494954751928	1.0	0.821593340021185	3	P09884	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.8382919145957297	0.9581399215081656	0.3379922071795405	1.0	0.824646305282337	2	P42695	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.824991249562478	0.9093271509740404	0.3631774628978985	1.0	0.8421881415193282	2	Q96CW5	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.824991249562478	0.9093271509740404	0.3631774628978985	1.0	0.8421881415193282	2	Q96CW5	1
+Exportin-2, central domain [IPR013713]	0.6593264627463382	0.9065660398106516	0.3646363272261381	1.0	0.8421881415193282	3	O95373	1
+GCF, C-terminal [IPR022783]	0.658023258521232	0.9015306436319798	0.367306248429887	1.0	0.8431569387152354	3	P16383	1
+Homeobox domain [IPR001356]	0.6578837417663058	0.9009918282800246	0.367592664537268	1.0	0.8431569387152354	3	P37275	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.5440375115872004	0.8951661954781687	0.3706982524677993	1.0	0.8435944746802603	8	P68036	1
+JmjC domain [IPR003347]	0.65478061381343	0.8890206520694394	0.3739919808099194	1.0	0.8445184011790361	3	Q7LBC6	1
+Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]	0.6530112044817938	0.8822061755964427	0.3776653229518176	1.0	0.847246484225302	3	Q9P2I0,Q5TA45	2
+Exportin-1/Importin-beta-like [IPR013598]	0.6180816734456595	0.8671767436803972	0.3858451766729001	1.0	0.8561331732651336	4	Q9HAV4,Q9Y5L0	2
+Pleckstrin homology domain [IPR001849]	0.5720503762954643	0.8581699938629855	0.3907986023247858	1.0	0.8588914001406143	18	P22059,Q6WCQ1,Q9NQW6,O14654,Q13464,Q9H4L5,Q96TA1	7
+Peptidase M16, middle/third domain [IPR032632]	0.8001400070003499	0.8195475559718544	0.4124740810109484	1.0	0.8657991706840936	2	O43847	1
+SET domain [IPR001214]	0.5227788757343642	0.8146231739998193	0.415288041291159	1.0	0.8674851340133626	7	Q9H7B4	1
+TOG domain [IPR034085]	0.5184588304949795	0.811551641222851	0.4170489494244833	1.0	0.8682822389657276	6	O00410,Q8TEX9,Q7Z460	3
+Metallo-beta-lactamase [IPR001279]	0.5281008026222472	0.7940382619887566	0.4271731570743236	1.0	0.8729697554303636	5	Q9P2I0,Q9BQ52,Q5TA45	3
+GNAT domain [IPR000182]	0.5982560770661438	0.7914210084272643	0.4286983545791336	1.0	0.8738823406107501	4	Q9H9T3,Q9GZZ1	2
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.5248840960564027	0.7801325368170815	0.4353128667001735	1.0	0.876802961058029	5	P42694	1
+Importin-beta, N-terminal domain [IPR001494]	0.5358766579250865	0.7760764847226214	0.4377038272097584	1.0	0.8794165987153598	13	O00410,O15397,Q8TEX9,O95373,Q9HAV4	5
+Glutathione S-transferase, N-terminal [IPR004045]	0.5118063038941787	0.7648098550078227	0.4443847785449875	1.0	0.8876659525074956	7	P28161,P21266,Q8TB36	3
+BAG domain [IPR003103]	0.7805390269513475	0.7503076793213244	0.4530694186142483	1.0	0.8960880043234483	2	Q9UL15	1
+B30.2/SPRY domain [IPR001870]	0.5108158000727896	0.7279979006795693	0.4666148713855427	1.0	0.9094843979429036	9	Q96S59,Q9UBL3	2
+SPRY domain [IPR003877]	0.5108158000727896	0.7279979006795693	0.4666148713855427	1.0	0.9094843979429036	9	Q96S59,Q9UBL3	2
+HR1 rho-binding domain [IPR011072]	0.7721386069303464	0.7211288319744098	0.4708302533809485	1.0	0.9162842547501686	2	Q13464	1
+HECT domain [IPR000569]	0.5006262735276436	0.7145107449538365	0.4749114143405624	1.0	0.9197120728762256	7	Q9ULT8,Q96J02	2
+Ubiquitin specific protease domain [IPR028889]	0.508915406152995	0.7036396919634695	0.4816571863115819	1.0	0.9281299489761086	10	Q86UV5,P51784,Q9Y4E8,Q96K76,Q14694	5
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.508915406152995	0.7036396919634695	0.4816571863115819	1.0	0.9281299489761086	10	Q86UV5,P51784,Q9Y4E8,Q96K76,Q14694	5
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.5063266144687539	0.7006926964180489	0.4834948149812472	1.0	0.9281408023466584	5	P41240,Q13546	2
+Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]	0.5046656544953876	0.684834711552055	0.4934482286400188	1.0	0.93681398560847	10	O00203	1
+PurM-like, C-terminal domain [IPR010918]	0.752537626881344	0.6543625259834698	0.5128782714847238	1.0	0.9479915159159706	2	P22102	1
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.7514875743787188	0.6508419143859459	0.5151485403010636	1.0	0.9488957463713484	2	O95336	1
+EGF-like calcium-binding domain [IPR001881]	0.7500875043752185	0.6461571542491165	0.5181775841573291	1.0	0.9519065423848952	2	O94813	1
+EGF-like domain [IPR000742]	0.7500875043752185	0.6461571542491165	0.5181775841573291	1.0	0.9519065423848952	2	O94813	1
+SGS domain [IPR007699]	0.736786839341967	0.6022082614137308	0.5470355171648262	1.0	0.9670820618826792	2	Q9HB71	1
+SH2 domain [IPR000980]	0.4785158442820498	0.5862278477338662	0.5577224102264378	1.0	0.9780408254915656	9	P41240,Q06124	2
+Fatty acid hydroxylase [IPR006694]	0.7311865593279662	0.5840196361902212	0.5592071010466098	1.0	0.9786900295135226	2	O75845	1
+SNF2, N-terminal [IPR000330]	0.4767557282880696	0.5637428536733149	0.5729291483246166	1.0	0.9888970206776108	10	Q9UNY4,Q2NKX8,Q14527	3
+Domain of unknown function DUF1899 [IPR015048]	0.72033601680084	0.5493501547927526	0.5827651740495092	1.0	0.9965518796170232	2	Q9ULV4	1
+Ovarian carcinoma immunoreactive antigen domain [IPR009764]	0.7168358417920896	0.5383343854509416	0.5903462163889648	1.0	0.9965518796170232	2	Q9NX40	1
+MAGE homology domain [IPR002190]	0.7112355617780887	0.520886990687902	0.6024454984980312	1.0	0.9965518796170232	2	Q9UNF1	1
+C2 domain [IPR000008]	0.4690820073696314	0.5025403984317679	0.615287442533972	1.0	0.9965518796170232	12	Q9Y426,Q96J02,Q86YS7	3
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4543086067183986	0.4986306414513519	0.6180396146419906	1.0	0.9965518796170232	8	Q00013	1
+Guanylate kinase-like domain [IPR008144]	0.4543086067183986	0.4986306414513519	0.6180396146419906	1.0	0.9965518796170232	8	Q00013	1
+Methylthiotransferase, N-terminal [IPR013848]	0.7028351417570877	0.4951414859630754	0.6205002512782238	1.0	0.9965518796170232	2	Q96SZ6	1
+TRAM domain [IPR002792]	0.7028351417570877	0.4951414859630754	0.6205002512782238	1.0	0.9965518796170232	2	Q96SZ6	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.4527356375228639	0.4819814751803068	0.6298191060149054	1.0	0.9965518796170232	5	P04350,Q9BUF5,P07437	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.4527356375228639	0.4819814751803068	0.6298191060149054	1.0	0.9965518796170232	5	P04350,Q9BUF5,P07437	3
+THUMP domain [IPR004114]	0.6940847042352116	0.4688916332979462	0.6391470970061688	1.0	0.9965518796170232	2	Q9NXG2	1
+Putative RNA methylase domain [IPR000241]	0.6940847042352116	0.4688916332979462	0.6391470970061688	1.0	0.9965518796170232	2	Q7Z4G4	1
+Beta-Casp domain [IPR022712]	0.507707386759134	0.4664588100860441	0.640887124295725	1.0	0.9965518796170232	4	Q9P2I0,Q5TA45	2
+CTP synthase GATase domain [IPR033828]	0.689884494224711	0.4565063324688269	0.6480259182225951	1.0	0.9965518796170232	2	P17812	1
+CTP synthase, N-terminal [IPR017456]	0.689884494224711	0.4565063324688269	0.6480259182225951	1.0	0.9965518796170232	2	P17812	1
+Syntaxin 6, N-terminal [IPR015260]	0.6839341967098354	0.439207252410223	0.6605113705197039	1.0	0.9965518796170232	2	O43752	1
+Phosphofructokinase domain [IPR000023]	0.517507002801122	0.4041207808526265	0.6861239043129874	1.0	0.9965518796170232	3	P08237,Q01813	2
+Zinc finger C2H2-type [IPR013087]	0.4613611873780755	0.4037227763652711	0.68641658889586	1.0	0.9965518796170232	17	Q9Y2X9,P37275,Q92610,O43670,Q86UK7,Q96KM6,Q7Z2T5	7
+Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]	0.6713335666783338	0.4035679115666617	0.6865304861011812	1.0	0.9965518796170232	2	P47897	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.4387031950051763	0.3944841056196363	0.6932236596978092	1.0	0.9965518796170232	11	P28161,P21266,Q8TB36,O43324	4
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.6657332866643331	0.3881794443173988	0.6978832438889966	1.0	0.9965518796170232	2	Q9H993	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6611830591529575	0.3758882289871645	0.7069999917981344	1.0	0.9965518796170232	2	P10644	1
+HOOK, N-terminal [IPR043936]	0.6520826041302064	0.3518922177655774	0.7249190957306337	1.0	0.9965518796170232	2	Q86VS8	1
+Phosphoribosyltransferase domain [IPR000836]	0.4126928471248143	0.3469377091997319	0.7286381162207194	1.0	0.9965518796170232	7	P07741,Q06203,P60891,P00492,O60256,P11172	6
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4657468274437242	0.3350628112705933	0.7375777052722108	1.0	0.9965518796170232	4	O00487	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.4657087264772004	0.3349511695236492	0.7376619216035758	1.0	0.9965518796170232	4	Q9H0H5	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.6356317815890793	0.3105820345454261	0.7561183865616485	1.0	0.9965518796170232	2	Q7L576	1
+CS domain [IPR007052]	0.4053829944772428	0.3074274432453479	0.7585180422291549	1.0	0.9965518796170232	8	Q9HB71,Q15185,Q9UHD1	3
+CLASP N-terminal domain [IPR024395]	0.6331816590829542	0.3046652576727077	0.7606211127201634	1.0	0.9965518796170232	2	Q7Z460	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.6111305565278263	0.2542878225705201	0.7992732068589792	1.0	0.9965518796170232	2	P31949	1
+Nucleoside phosphorylase domain [IPR000845]	0.6100805040252013	0.2520209279068041	0.8010248876578643	1.0	0.9965518796170232	2	Q13126	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.4562324929972007	0.2376079076832456	0.812185216706738	1.0	0.9965518796170232	3	Q13630,Q9NRG7	2
+Pre-PUA domain [IPR041366]	0.6016800840042	0.2343284531149616	0.8147299983589671	1.0	0.9965518796170232	2	P41214	1
+Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]	0.4282884960081543	0.2331738446704047	0.8156264150407231	1.0	0.9965518796170232	4	O60256	1
+p21 activated kinase binding domain [IPR033923]	0.6006300315015751	0.2321726010727083	0.8164039575349988	1.0	0.9965518796170232	2	Q13177	1
+CRIB domain [IPR000095]	0.6006300315015751	0.2321726010727083	0.8164039575349988	1.0	0.9965518796170232	2	Q13177	1
+LIS1 homology motif [IPR006594]	0.3769437910320005	0.2209602529926043	0.8251233815574275	1.0	0.9965518796170232	7	Q9Y4B6,Q96S59,O95684	3
+Cullin homology domain [IPR016158]	0.3750682115441485	0.214878192797662	0.8298622873889161	1.0	0.9965518796170232	7	Q13618,Q9UJX6	2
+Cullin, N-terminal [IPR001373]	0.3750682115441485	0.214878192797662	0.8298622873889161	1.0	0.9965518796170232	7	Q13618,Q9UJX6	2
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.5862793139656983	0.2039658194996732	0.8383802094823969	1.0	0.9965518796170232	2	Q9NP81	1
+Sec63 domain [IPR004179]	0.4394870679595642	0.2000598045843895	0.8414338091099569	1.0	0.9965518796170232	3	Q8N3C0	1
+WHIM2 domain [IPR028941]	0.4390756302521026	0.1991841430943176	0.8421187028757866	1.0	0.9965518796170232	3	Q9UIG0,Q12830	2
+DDT domain [IPR018501]	0.4390756302521026	0.1991841430943176	0.8421187028757866	1.0	0.9965518796170232	3	Q9UIG0,Q12830	2
+WHIM1 domain [IPR028942]	0.4390756302521026	0.1991841430943176	0.8421187028757866	1.0	0.9965518796170232	3	Q96T23,Q9UIG0	2
+Ras GTPase-activating domain [IPR001936]	0.4141276713211814	0.1991132624182984	0.8421741470357798	1.0	0.9965518796170232	4	Q14C86	1
+K Homology domain [IPR004087]	0.4185462015452807	0.1965027686926084	0.8442166658097814	1.0	0.9965518796170232	22	Q15365,Q9Y2W6	2
+PDZ domain [IPR001478]	0.4077110954873555	0.1932071829455552	0.8467967135476406	1.0	0.9965518796170232	19	O14745,Q9Y4G8,Q14160,Q00013,Q8N3R9	5
+Valyl tRNA synthetase, anticodon-binding domain [IPR033705]	0.5778788939446973	0.1885513058710256	0.8504445004027776	1.0	0.9965518796170232	2	Q5ST30	1
+Rho GTPase-activating protein domain [IPR000198]	0.4088814876888731	0.1871636696119491	0.8515323088992419	1.0	0.9965518796170232	4	Q07960	1
+WHEP-TRS domain [IPR000738]	0.4066549912434375	0.182203984934667	0.855422645816255	1.0	0.9965518796170232	4	P07814,P41250,P23381	3
+K Homology domain, type 1 [IPR004088]	0.413517337774638	0.1812067984438552	0.8562052585549482	1.0	0.9965518796170232	22	Q15365,Q9Y2W6	2
+SPRY-associated [IPR006574]	0.5719285964298213	0.1781263680562508	0.8586237344531442	1.0	0.9965518796170232	2	Q14258	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5712285614280715	0.1769268694551945	0.8595658327847464	1.0	0.9965518796170232	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5712285614280715	0.1769268694551945	0.8595658327847464	1.0	0.9965518796170232	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5712285614280715	0.1769268694551945	0.8595658327847464	1.0	0.9965518796170232	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5712285614280715	0.1769268694551945	0.8595658327847464	1.0	0.9965518796170232	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5712285614280715	0.1769268694551945	0.8595658327847464	1.0	0.9965518796170232	2	A0FGR8	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.3591573601612278	0.1755384232053314	0.8606565821082259	1.0	0.9965518796170232	6	Q9HD20,Q04656	2
+Protein kinase domain [IPR000719]	0.4814836990095837	0.175002689252018	0.8610775204784333	1.0	0.9965518796170232	44	Q00534,P41240,Q8TD19,Q13546,O14965,Q14012,Q96KB5,O14757,Q99570,Q00535,O14976,P49841,Q86Y07,Q99640,P50613,P11802,Q9UHY1,P50750	18
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.4026284983809978	0.173405537769328	0.8623326725364111	1.0	0.9965518796170232	4	O43175	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.4026284983809978	0.173405537769328	0.8623326725364111	1.0	0.9965518796170232	4	O43175	1
+ENTH  domain [IPR013809]	0.4208683473389374	0.1627381531058946	0.8707246055708233	1.0	0.9965518796170232	3	O00291,Q14677	2
+B3/B4 tRNA-binding domain [IPR005146]	0.5509275463773187	0.1446076933959308	0.8850206226360393	1.0	0.9965518796170232	2	Q8N1G4	1
+Domain of unknown function DUF1747 [IPR013719]	0.5495274763738185	0.1425538091617706	0.8866425797382718	1.0	0.9965518796170232	2	Q08945	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.5477773888694435	0.1400179828851502	0.8886457820659057	1.0	0.9965518796170232	2	Q2NL82	1
+Bms1/Tsr1-type G domain [IPR030387]	0.5477773888694435	0.1400179828851502	0.8886457820659057	1.0	0.9965518796170232	2	Q2NL82	1
+AARP2CN [IPR012948]	0.5477773888694435	0.1400179828851502	0.8886457820659057	1.0	0.9965518796170232	2	Q2NL82	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.383887915936958	0.1354028938363467	0.8922933362542165	1.0	0.9965518796170232	4	O00217,P21912,P61221	3
+Cold-shock (CSD) domain [IPR019844]	0.3806949851177997	0.129419088268324	0.897026044443326	1.0	0.9965518796170232	4	P67809	1
+Cold-shock protein, DNA-binding [IPR002059]	0.3806949851177997	0.129419088268324	0.897026044443326	1.0	0.9965518796170232	4	P67809	1
+Cold shock domain [IPR011129]	0.3806949851177997	0.129419088268324	0.897026044443326	1.0	0.9965518796170232	4	P67809	1
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.5348267413370668	0.1223329900482301	0.9026353059222648	1.0	0.9965518796170232	2	Q13526	1
+Malic enzyme, NAD-binding [IPR012302]	0.5327266363318164	0.1196426950237506	0.9047661968821892	1.0	0.9965518796170232	2	P48163	1
+Malic enzyme, N-terminal domain [IPR012301]	0.5327266363318164	0.1196426950237506	0.9047661968821892	1.0	0.9965518796170232	2	P48163	1
+Bromo adjacent homology (BAH) domain [IPR001025]	0.3691768826620006	0.1090339640991034	0.913175551462346	1.0	0.9965518796170232	4	Q86U86,O94776,P26358	3
+Ubiquitin-associated domain [IPR015940]	0.3556260371519184	0.1019586724044642	0.9187894787156492	1.0	0.9965518796170232	13	Q13501,Q9Y5A7	2
+Peptidase M16, N-terminal [IPR011765]	0.3358090304908628	0.1016329850983746	0.919047996679681	1.0	0.9965518796170232	7	O43847	1
+Peptidase M16, C-terminal [IPR007863]	0.3358090304908628	0.1016329850983746	0.919047996679681	1.0	0.9965518796170232	7	O43847	1
+Man1/Src1, C-terminal [IPR018996]	0.5124256212810638	0.0961199718986278	0.9234252894671748	1.0	0.9965518796170232	2	Q9Y2U8	1
+ELMO domain [IPR006816]	0.5110255512775638	0.0946597131059831	0.9245851185171392	1.0	0.9965518796170232	2	Q96JJ3	1
+PWWP domain [IPR000313]	0.330847707626466	0.0893628019078358	0.928793584936148	1.0	0.9965518796170232	7	P51858	1
+Double-stranded RNA-binding domain [IPR014720]	0.3470115738411693	0.0887442492079529	0.9292851654607172	1.0	0.9965518796170232	12	Q9NX74,P55265,Q9UPY3,O95793	4
+AP complex, mu/sigma subunit [IPR022775]	0.3199018920812883	0.0787625160521103	0.9372215192447456	1.0	0.9965518796170232	5	Q9Y2T2,P48444,P61923,P53680	4
+Copine, C2B domain [IPR037768]	0.490024501225061	0.0751321648650596	0.9401095562783036	1.0	0.9965518796170232	2	Q99829	1
+Copine, C-terminal [IPR010734]	0.490024501225061	0.0751321648650596	0.9401095562783036	1.0	0.9965518796170232	2	Q99829	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.4875743787189358	0.0731332879093474	0.9417000526515322	1.0	0.9965518796170232	2	Q96G03	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.4875743787189358	0.0731332879093474	0.9417000526515322	1.0	0.9965518796170232	2	Q96G03	1
+Ubiquitin-activating enzyme, SCCH domain [IPR019572]	0.473923696184809	0.0629966123094434	0.9497692019501768	1.0	0.9965518796170232	2	A0AVT1	1
+Ubiquitin-activating enzyme E1, C-terminal [IPR018965]	0.473923696184809	0.0629966123094434	0.9497692019501768	1.0	0.9965518796170232	2	A0AVT1	1
+Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]	0.473923696184809	0.0629966123094434	0.9497692019501768	1.0	0.9965518796170232	2	A0AVT1	1
+Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]	0.473923696184809	0.0629966123094434	0.9497692019501768	1.0	0.9965518796170232	2	A0AVT1	1
+BRCT domain [IPR001357]	0.3276729241415451	0.0593692920842909	0.9526579712685246	1.0	0.9965518796170232	10	P38398	1
+EB1, C-terminal [IPR004953]	0.4683234161708084	0.059307049287853	0.952707546480325	1.0	0.9965518796170232	2	Q15555	1
+W2 domain [IPR003307]	0.3176718092566533	0.0591275498011543	0.9528505154555198	1.0	0.9965518796170232	7	P55010,P78344,O43432,Q04637,Q9Y6E2,Q13144	6
+Transcription elongation factor S-II, central domain [IPR003618]	0.3403175842895075	0.0553239374536878	0.9558803920372434	1.0	0.9965518796170232	3	Q9BTC0	1
+Ion transporter-like, CBS domain [IPR044751]	0.4539726986349316	0.0510055769877527	0.9593210765411408	1.0	0.9965518796170232	2	Q6P4Q7	1
+CNNM, transmembrane domain [IPR002550]	0.4539726986349316	0.0510055769877527	0.9593210765411408	1.0	0.9965518796170232	2	Q6P4Q7	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4508225411270561	0.0493925713553157	0.9606064481376884	1.0	0.9965518796170232	2	O00154	1
+Glutaredoxin [IPR002109]	0.3301820728291338	0.0475212053362397	0.9620978300117868	1.0	0.9965518796170232	3	O76003,P35754	2
+FAD dependent oxidoreductase [IPR006076]	0.3287815126050439	0.04652915182438	0.9628884994461996	1.0	0.9965518796170232	3	P43304,Q9H9P8	2
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.4431221561078052	0.0457452959391803	0.9635132606380308	1.0	0.9965518796170232	2	O00443	1
+Mu homology domain [IPR028565]	0.3197898423817913	0.0426371496028086	0.9659907813041392	1.0	0.9965518796170232	4	Q9Y2T2,P48444,Q9BXS5	3
+Cullin protein, neddylation domain [IPR019559]	0.3042411496670206	0.0382699278727275	0.9694724672956568	1.0	0.9965518796170232	6	Q13618,Q13620,Q13619,Q13617,Q13616	5
+ARID DNA-binding domain [IPR001606]	0.4235211760588028	0.0381859589940266	0.969539415831184	1.0	0.9965518796170232	2	Q68CP9	1
+Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]	0.4231711585579276	0.038071479945937	0.96963069052448	1.0	0.9965518796170232	2	O95782	1
+AP180 N-terminal homology (ANTH) domain [IPR011417]	0.4207210360518023	0.0372887009534627	0.9702548145615832	1.0	0.9965518796170232	2	O00291	1
+SAM domain [IPR041418]	0.4200210010500523	0.0370709419737664	0.970428441042296	1.0	0.9965518796170232	2	Q9NZI7	1
+CP2 transcription factor [IPR007604]	0.4200210010500523	0.0370709419737664	0.970428441042296	1.0	0.9965518796170232	2	Q9NZI7	1
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.4196709835491771	0.0369630315174166	0.9705144821598914	1.0	0.9965518796170232	2	Q15008	1
+RasGAP protein, C-terminal [IPR000593]	0.3133753501400583	0.0369059562014857	0.970559990622341	1.0	0.9965518796170232	3	Q86VI3,P46940	2
+HDGF-related, PWWP domain [IPR035496]	0.3112745098039238	0.0357673413917443	0.971467874189876	1.0	0.9965518796170232	3	Q7Z4V5,P51858	2
+Coatomer subunit gamma, C-terminal [IPR032154]	0.4151207560378016	0.0356177298482137	0.9715871709168028	1.0	0.9965518796170232	2	Q9Y678	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.4151207560378016	0.0356177298482137	0.9715871709168028	1.0	0.9965518796170232	2	Q9Y678	1
+Major sperm protein (MSP) domain [IPR000535]	0.4098704935246761	0.0341930327655695	0.9727232223416248	1.0	0.9965518796170232	2	Q9P0L0	1
+La protein, xRRM domain [IPR014886]	0.4095204760238008	0.0341027168041626	0.972795242050282	1.0	0.9965518796170232	2	Q4G0J3	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.4077703885194256	0.0336596185387831	0.9731485804495486	1.0	0.9965518796170232	2	P15531	1
+Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]	0.4074203710185508	0.0335726777941237	0.9732179099435878	1.0	0.9965518796170232	2	Q5JTZ9	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.4074203710185508	0.0335726777941237	0.9732179099435878	1.0	0.9965518796170232	2	Q5JTZ9	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	0.9965518796170232	2	Q9H9Y6	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	0.9965518796170232	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	0.9965518796170232	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	0.9965518796170232	2	Q9H9Y6	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.3825691284564225	0.0286728399560557	0.9771255180339484	1.0	0.9965518796170232	2	Q9H9Y6	1
+3'-5' exonuclease domain [IPR002562]	0.3773188659432969	0.0279161098294097	0.9777290596650718	1.0	0.9965518796170232	2	Q9NVH0	1
+Zinc finger, CHHC-type [IPR012996]	0.2941176470588255	0.027866103888548	0.9777689431172676	1.0	0.9965518796170232	3	P52597,P31943	2
+Zinc finger, UBP-type [IPR001607]	0.3734686734336715	0.0274129508837488	0.978130368819614	1.0	0.9965518796170232	2	P45974	1
+Ribosomal protein L2, C-terminal [IPR022669]	0.352117605880294	0.0252959552545717	0.9798189001395988	1.0	0.9965518796170232	2	Q5T653	1
+Ribosomal Proteins L2, RNA binding domain [IPR022666]	0.352117605880294	0.0252959552545717	0.9798189001395988	1.0	0.9965518796170232	2	Q5T653	1
+Methylglyoxal synthase-like domain [IPR011607]	0.345817290864543	0.0248520756656233	0.9801729534922972	1.0	0.9965518796170232	2	P27708	1
+I/LWEQ domain [IPR002558]	0.3398669933496673	0.0244936102217356	0.980458880491867	1.0	0.9965518796170232	2	O00291	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.3276163808190409	0.0239128002199331	0.980922164104036	1.0	0.9965518796170232	2	Q5T9A4	1
+Fxr1, tudor domain [IPR041560]	0.279761904761907	0.0229477440664335	0.9816919561510392	1.0	0.9965518796170232	3	Q06787,P51114	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.279761904761907	0.0229477440664335	0.9816919561510392	1.0	0.9965518796170232	3	Q06787,P51114	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.279761904761907	0.0229477440664335	0.9816919561510392	1.0	0.9965518796170232	3	Q06787,P51114	2
+Agenet-like domain [IPR008395]	0.279761904761907	0.0229477440664335	0.9816919561510392	1.0	0.9965518796170232	3	Q06787,P51114	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.2796639831991596	0.0229101355295716	0.9817219555350352	1.0	0.9965518796170232	2	P51114	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}