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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +7 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/basic/plot_0.png +3 -0
  12. interpro_binding_site/consensus.joblib +3 -0
  13. interpro_binding_site/df_merge.tsv +1 -0
  14. interpro_binding_site/metrics.json +7 -0
  15. interpro_binding_site/paths.json +1 -0
  16. interpro_binding_site/result.tsv +7 -0
  17. interpro_binding_site/selections.json +1 -0
  18. interpro_conserved_site/advanced/idx2term.json +1 -0
  19. interpro_conserved_site/advanced/plot_0.png +3 -0
  20. interpro_conserved_site/basic/idx2term.json +1 -0
  21. interpro_conserved_site/basic/plot_0.png +3 -0
  22. interpro_conserved_site/basic/plot_1.png +3 -0
  23. interpro_conserved_site/basic/plot_2.png +3 -0
  24. interpro_conserved_site/consensus.joblib +3 -0
  25. interpro_conserved_site/df_merge.tsv +4 -0
  26. interpro_conserved_site/metrics.json +7 -0
  27. interpro_conserved_site/paths.json +1 -0
  28. interpro_conserved_site/result.tsv +37 -0
  29. interpro_conserved_site/selections.json +1 -0
  30. interpro_domain/advanced/idx2term.json +1 -0
  31. interpro_domain/advanced/plot_0.png +3 -0
  32. interpro_domain/advanced/plot_1.png +3 -0
  33. interpro_domain/basic/idx2term.json +1 -0
  34. interpro_domain/basic/plot_0.png +3 -0
  35. interpro_domain/basic/plot_1.png +3 -0
  36. interpro_domain/basic/plot_10.png +3 -0
  37. interpro_domain/basic/plot_11.png +3 -0
  38. interpro_domain/basic/plot_12.png +3 -0
  39. interpro_domain/basic/plot_13.png +3 -0
  40. interpro_domain/basic/plot_14.png +3 -0
  41. interpro_domain/basic/plot_15.png +3 -0
  42. interpro_domain/basic/plot_16.png +3 -0
  43. interpro_domain/basic/plot_17.png +3 -0
  44. interpro_domain/basic/plot_18.png +3 -0
  45. interpro_domain/basic/plot_19.png +3 -0
  46. interpro_domain/basic/plot_2.png +3 -0
  47. interpro_domain/basic/plot_3.png +3 -0
  48. interpro_domain/basic/plot_4.png +3 -0
  49. interpro_domain/basic/plot_5.png +3 -0
  50. interpro_domain/basic/plot_6.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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interpro_active_site/basic/idx2term.json ADDED
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interpro_active_site/consensus.joblib ADDED
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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3300,
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+ "annotations_size": 55,
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+ "title": "Average number of proteins per term",
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interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C191/C191_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.4757133884232477 1.211704895949102 0.2256253643252623 0.9999992196102316 0.7755871898680894 6 P49459,P68036 2
3
+ Adenosine/AMP deaminase active site [IPR006650] 0.8265615524560344 1.0426344773754324 0.2971176148784789 0.9999999962108108 0.7895872853178563 2 Q01433 1
4
+ Nucleoside diphosphate kinase, active site [IPR023005] 0.7310491206792005 0.6496140590381103 0.5159415494039283 1.0 0.93326316494528 2 Q13232 1
5
+ ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.4467071234229189 0.0521566268759484 0.95840389260355 1.0 1.0 4 P38606 1
6
+ L-lactate dehydrogenase, active site [IPR018177] 0.4575500303214088 0.0369754260520523 0.9705045995078035 1.0 1.0 2 P00338 1
7
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.3621474067333832 0.0017891967703324 0.9985724282823764 1.0 1.0 3 Q9UBT2,Q8TBC4 2
interpro_active_site/selections.json ADDED
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+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP8", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CIT", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP3K4", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME3", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PPIP5K2", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "STK38", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "YES1"], "leading_proteins": ["AMPD2", "ATP6V1A", "LDHA", "NME3", "UBA2", "UBA3", "UBE2A", "UBE2L3"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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+ Peptidase M16, zinc-binding site [IPR001431] 0.6773899848254732 1.3042383132838995 0.1921523404512881 0.9983408558004376 0.8198692248101225 5 P22695,O75439,Q10713,O43847 4
3
+ Beta tubulin, autoregulation binding site [IPR013838] 0.6606980273141176 1.2301744290052787 0.2186317932826993 0.9993895190955 0.8198692248101225 5 Q9BUF5,P07437,Q9BVA1,P68371 4
4
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4082280987718462 0.2637472506106634 0.7919746835053869 1.0 0.9850847512212164 37 Q02818,O95302,P80303,P30626,O43852,Q9BRK5,Q14257,P42566,Q9NWM8 9
5
+ Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838] 0.5342631898120088 0.10808236359192 0.9139303580068784 1.0 0.9850847512212164 2 P00505 1
6
+ Hexokinase, binding site [IPR019807] 0.4812007277137676 0.0518500238139796 0.958648195888308 1.0 0.9850847512212164 2 P52789 1
7
+ PPM-type phosphatase, divalent cation binding [IPR000222] 0.4388838337882921 0.0235554448205841 0.9812072121620652 1.0 0.9850847512212164 3 Q9H0C8,O15355 2
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT2", "APEX1", "ARAF", "ARG2", "AURKA", "AURKB", "BPNT1", "BUB1", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CIT", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK38", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALU", "EPS15", "FKBP14", "FKBP9", "GOT2", "HK2", "ILKAP", "NRDC", "NUCB1", "NUCB2", "PMPCA", "PMPCB", "PPM1G", "RCN2", "SDF4", "SRI", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UQCRC2"]}
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+ Guanylate kinase, conserved site [IPR020590] 2 6 2.1304465219042323 0.0331347664645396 2.3980582524271843 5.25 0.6064346340666176 0.4240795168052628 1.6195996498310523 1.4740884957165508 0.9685287933135084 0.3034897017004088 0.3091984492206326 1.0 1.0 1.0 0.4217257773445009
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ 14-3-3 protein, conserved site [IPR023409] 0.7767596184908421 2.700929240546591 0.006914604773782 0.8516410928598499 0.6767773738437535 6 P27348,Q04917,P61981,P62258 4
3
+ Intermediate filament protein, conserved site [IPR018039] 0.6774190676448235 2.183974749508281 0.0289641035597461 0.999691181484722 0.6767773738437535 8 P08670,P07197,P07196,P20700,P48681,Q16352 6
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+ Guanylate kinase, conserved site [IPR020590] 0.655283156262247 2.1304465219042323 0.0331347664645396 0.9999054558523082 0.6767773738437535 6 Q9NZW5,Q14168 2
5
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.6203214631455924 1.9311988800508917 0.0534584624621217 0.9999997255828846 0.6767773738437535 7 P28070,P49721,P28074 3
6
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8093508141457328 1.882492884724304 0.0597691250564991 0.99999995639967 0.6767773738437535 5 P48735,O75874 2
7
+ Chaperonin TCP-1, conserved site [IPR002194] 0.603151329161017 1.8185054446492763 0.0689869153092233 0.9999999970970416 0.6767773738437535 8 P50990,P48643,P50991,Q99832 4
8
+ Haem oxygenase conserved site [IPR018207] 0.9244996967859312 1.4738200532184955 0.1405300475658042 1.0 0.6767773738437535 2 P30519 1
9
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.9181322013341422 1.445476882448823 0.1483239818411386 1.0 0.6767773738437535 2 P09429 1
10
+ Mini-chromosome maintenance, conserved site [IPR018525] 0.5142683667273747 1.415126921429141 0.1570312861444769 1.0 0.6767773738437535 6 P33992,Q14566,P25205,P33993,P33991 5
11
+ Tubulin, conserved site [IPR017975] 0.6606980273141176 1.2301744290052787 0.2186317932826993 1.0 0.7332163799114917 5 Q9BUF5,P07437,Q9BVA1,P68371 4
12
+ Dynein light chain, type 1/2, conserved site [IPR019763] 0.8444511825348702 1.1202038739601723 0.2626268935026887 1.0 0.785026040361298 2 P63167 1
13
+ Ribosomal protein L3, conserved site [IPR019926] 0.8332322619769561 1.0714636599876564 0.2839610021296663 1.0 0.8058493835967351 2 P09001 1
14
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.8195329087048893 0.9795409936700374 0.3273127438515124 1.0 0.8487283422748276 3 P08238,P07900 2
15
+ Sterol reductase, conserved site [IPR018083] 0.7722862340812622 0.813754281466843 0.4157857308190935 1.0 0.8861274394076705 2 Q14739 1
16
+ Ubiquitin interacting motif [IPR003903] 0.7473724887438824 0.7041827646284099 0.4813189630330619 1.0 0.890005858820939 3 P42566 1
17
+ XPG conserved site [IPR019974] 0.7446937537901768 0.7027342865377106 0.4822213562338906 1.0 0.890005858820939 2 Q9UQ84 1
18
+ Helix-hairpin-helix motif, class 2 [IPR008918] 0.7446937537901768 0.7027342865377106 0.4822213562338906 1.0 0.890005858820939 2 Q9UQ84 1
19
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.6999834080081887 0.6702718746531583 0.5026844928788652 1.0 0.901003909887124 4 Q8N4Q0 1
20
+ Tetraspanin, conserved site [IPR018503] 0.7348070430665694 0.6585508941040712 0.5101842051161796 1.0 0.901003909887124 3 Q9H1Z9 1
21
+ Thioredoxin, conserved site [IPR017937] 0.3881120038350063 0.6364214448414279 0.5245017671008525 1.0 0.9187132863231492 11 Q9H1E5,Q14554,Q9H3N1 3
22
+ Ribosomal protein L7Ae conserved site [IPR004037] 0.6937537901758651 0.5118694982911235 0.6087423466042172 1.0 0.9732799146288356 2 P55769 1
23
+ Ubiquitin specific protease, conserved site [IPR018200] 0.3683263850972088 0.4806123454784651 0.6307920395710465 1.0 0.9996690855790924 14 Q96K76,P51784,Q96RU2,P45974,Q14694 5
24
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.6424815852361303 0.4781859043274903 0.6325178941482257 1.0 0.9996690855790924 4 P56545 1
25
+ Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.3343421547489615 0.3678470617954933 0.7129872752695485 1.0 1.0 12 P09417,Q06136 2
26
+ 4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.5890406187115367 0.2208793115370976 0.8251864065902477 1.0 1.0 3 P61221 1
27
+ Dynamin, GTPase region, conserved site [IPR019762] 0.5856839551107111 0.2134405079601465 0.8309833875832822 1.0 1.0 3 O00429,Q9UQ16 2
28
+ Chromo domain, conserved site [IPR023779] 0.5419084148225851 0.2057269673318979 0.8370041922334965 1.0 1.0 4 P83916 1
29
+ Profilin conserved site [IPR027310] 0.58732565191025 0.2030641754077312 0.839084872221026 1.0 1.0 2 P35080 1
30
+ Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866] 0.5580680012534704 0.1576713857229238 0.8747157492981159 1.0 1.0 3 Q9P2R7 1
31
+ Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4963614311704079 0.0644058371632327 0.9486470822948788 1.0 1.0 2 P24534 1
32
+ Vinculin, conserved site [IPR000633] 0.480594299575502 0.0513999370156761 0.959006834962685 1.0 1.0 2 P18206 1
33
+ Glycoside hydrolase, family 29, conserved site [IPR018526] 0.4642207398423305 0.0406405848075008 0.9675824288710742 1.0 1.0 2 Q9BTY2 1
34
+ RNA polymerase, beta subunit, conserved site [IPR007121] 0.4430587124003841 0.0257689913488081 0.9794415949508506 1.0 1.0 3 Q9NW08 1
35
+ Methylthiotransferase, conserved site [IPR020612] 0.3747725894481526 0.0151375363774143 0.987922454689166 1.0 1.0 2 Q96SZ6 1
36
+ Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.3620375985445745 0.0141453804112425 0.9887139957372348 1.0 1.0 2 Q9UBT2 1
37
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4131028207461248 0.0126983358462515 0.9898684661622624 1.0 1.0 3 Q9Y2T2,Q9BXS5 2
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", 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interpro_domain/advanced/idx2term.json ADDED
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Git LFS Details

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Git LFS Details

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interpro_domain/basic/idx2term.json ADDED
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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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Git LFS Details

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