msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Protein localization	0.5956613866585416	3.707714175244917	0.0002091385168856	0.2460027254856196	0.2702448721699915	69	P21796,Q99595,Q9Y3D6,Q9Y5J9,P09601,Q8NBU5,Q9NS69,O60830,O75874,Q5JRX3,Q8N4H5,Q9UJS0,P50402,P40855,Q9BY49,Q9NR77,O14925,Q13505,P51648,P06576,Q10713,P12235,O75431,O00116,Q13190,Q15388,O96008,Q3ZCQ8,P12236,O75381	30
Mitochondrial protein import	0.6743677345833383	3.3497724332159606	0.0008087797742108	0.664554059797098	0.2702448721699915	34	P21796,Q9UJS0,P06576,Q99595,Q9Y5J9,P12235,Q15388,O75431,Q9NS69,O96008,O60830,Q3ZCQ8,P12236,Q5JRX3,Q8N4H5,O14925,Q13505	17
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.6176534610383785	3.2902716790569406	0.0010009069339629	0.7412520966241064	0.2702448721699915	51	P00846,P06576,O43676,O95167,P13073,P56385,Q9BQ95,O96000,P21912,O43819,O75964,Q9P032,P22695,Q9UDW1,Q9NPL8,O75306,O14949,P00403	18
Cristae formation	0.7078884715180804	2.9089539135231437	0.0036264031415422	0.9925871666919318	0.5006011168944642	21	P00846,P06576,O75431,O75964,Q5XKP0,Q6UXV4,Q9BUR5,Q13505	8
Respiratory electron transport	0.5894195760484436	2.8890945989681933	0.0038635282585026	0.9946242909651482	0.5006011168944642	41	O43676,O95167,P13073,Q9BQ95,P21912,P22695,Q9UDW1,O75306,O14949,P00403	10
Mitochondrial biogenesis	0.6046144851184396	2.7304877599881685	0.0063240681445921	0.9998092605493756	0.5153183067122225	31	P00846,P06576,P56385,O75431,O00411,O75964,Q5XKP0,Q6UXV4,Q9BUR5,Q13505	10
The citric acid tca cycle and respiratory electron transport	0.4777081525386749	2.684369614030961	0.0072666721145575	0.999947032075492	0.5153183067122225	81	P00846,P21796,Q9BQ95,P35613,O75964,Q9P032,P22695,Q9UDW1,O14949,Q13423,O43676,P00403,P06576,O95167,P56385,O96000,O43819,P07195,O75306,P13073,P21912,Q9NPL8	22
Mitochondrial calcium ion transport	0.7510585330092949	2.589438662420372	0.0096132547351979	0.9999978297679916	0.5153183067122225	14	P21796,Q10713,Q99623,Q9Y277,O95202,P45880,Q9Y4W6,Q9UJZ1	8
Slc mediated transmembrane transport	0.6879056124118247	2.5435783016522073	0.0109723461394524	0.999999660071836	0.5153183067122225	18	Q70HW3,Q8TAD4,Q8TB61,P12235,P35613,Q9UBX3,P12236,Q9Y6M7	8
Sphingolipid de novo biosynthesis	0.7981803135400485	2.5174881544338423	0.0118194943881226	0.99999989309924	0.5153183067122225	10	P51648,O95470,Q96G23,Q06136,Q9Y5P4	5
Organelle biogenesis and maintenance	0.4563235674711416	2.435190100500731	0.0148839678786631	0.999999998385744	0.5153183067122225	82	P00846,Q9BVA1,O95684,Q9Y512,O75935,O00411,O75964,P24539,P41208,A0AVF1,Q16891,Q6UXV4,A6NIH7,P07437,Q13561,Q9BUR5,Q13505,P06576,Q10713,P56385,P61163,P07900,P06493,O75431,Q9NX63,Q15154,P53350,Q96KP1,O43805,Q5XKP0,Q68CZ6,Q9NVH1,Q13885,O94927	34
Pink1 prkn mediated mitophagy	0.8298323806490299	2.4076247848868	0.0160566738880547	0.999999999676694	0.5153183067122225	8	P21796,Q15388,Q9NS69,O95140,Q8N4H5	5
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.7344210672359599	2.3586011645898126	0.0183439590922194	0.9999999999860326	0.5153183067122225	12	P51648,Q13190,P50402,P09601	4
Complex i biogenesis	0.6155636074035886	2.328304838803702	0.0198959225504717	0.99999999999835	0.5153183067122225	21	O43676,O95167,Q9BQ95,O96000,Q9P032,Q9NPL8,O75306	7
Class i peroxisomal membrane protein import	0.8065359825673095	2.3026389246141634	0.021299167180069	0.9999999999997616	0.5153183067122225	8	P51648,Q9Y3D6,Q8NBU5,P40855,O75381,Q9NR77	6
Glycerophospholipid biosynthesis	0.5587617435884489	2.301848193570491	0.0213437346378262	0.9999999999997756	0.5153183067122225	28	P48651,Q92604,Q9NPH0,Q8N2A8,Q9Y6K0,P35790,P40939,Q9NQZ5,Q8NF37	9
Mitophagy	0.72145024035725	2.291683143933436	0.0219239337802981	0.9999999999998992	0.5153183067122225	12	P21796,Q15388,Q9NS69,O95140,Q8N4H5	5
Formation of atp by chemiosmotic coupling	0.7465904889778073	2.2671109301055097	0.0233834500449152	0.9999999999999866	0.5153183067122225	10	P00846,P06576,P56385,O75964	4
Transport of small molecules	0.4653455106823795	2.2100466370552536	0.0271019257604205	1.0	0.5153183067122225	132	P21796,Q8TAD4,P09601,P61421,Q93050,P35613,P07237,P61289,P30519,Q9UL46,Q9HD20,P98194,Q9UJZ1,P25787,P40855,P49721,O95202,Q9BUN8,Q9UBX3,P45880,Q9Y4W6,Q10713,O00231,P43686,P12235,Q9UBV2,Q12797,Q8WTV0,P28074,P16615,Q70HW3,Q99797,P05023,Q8TB61,Q99623,Q9Y277,Q9NW15,O75477,P28066,P12236,Q9Y6M7,P28072,P05141,Q8N4V1	44
Synthesis of pc	0.8272530544397294	2.175203237765575	0.0296148896667289	1.0	0.5192220915595341	7	Q8NF37,Q9NQZ5,P35790	3
Metabolism of folate and pterines	0.8174721455554206	2.1327765020443277	0.032943064738681	1.0	0.5486508420846972	7	P00374	1
Phospholipid metabolism	0.4928939486730405	2.075364089522913	0.0379528037414631	1.0	0.5552402314539597	40	P48651,Q96N66,Q10713,Q9NPH0,Q01968,Q92604,Q8IV08,Q8N2A8,Q9Y6K0,P35790,Q8TBX8,Q53H12,P40939,Q9NTJ5,Q9NQZ5,Q8NF37	16
Ion transport by p type atpases	0.7165313125895544	2.051159598668727	0.040251406909326	1.0	0.5552402314539597	9	Q9HD20,P16615,P05023	3
Transport of inorganic cations anions and amino acids oligopeptides	0.7499037405784809	2.0418774135631477	0.0411636927447429	1.0	0.5552402314539597	8	Q70HW3,Q9UBX3	2
Ion channel transport	0.5299565509717983	2.0393987048175988	0.041410251580479	1.0	0.5552402314539597	26	P05023,P61421,Q93050,Q9NW15,Q12797,Q9HD20,P16615	7
Phosphorylation of the apc c	0.6952582627733076	2.0103877486248067	0.0443901661324579	1.0	0.5657256718480285	10	Q9UJX4,Q9UJX2,Q9UJX3,P06493,P53350	5
Defective cftr causes cystic fibrosis	0.4782723895992276	1.9603775647099395	0.0499516761459382	1.0	0.5860562574610487	42	P25787,O00231,P43686,Q92530,P49721,Q9UBV2,P62191,Q9BUN8,P25789,P61289,P28066,Q9UL46,P28074,O75477,P28072	15
Abc transporter disorders	0.4782723895992276	1.9603775647099395	0.0499516761459382	1.0	0.5860562574610487	42	P25787,O00231,P43686,Q92530,P49721,Q9UBV2,P62191,Q9BUN8,P25789,P61289,P28066,Q9UL46,P28074,O75477,P28072	15
Signaling by ptk6	0.6711380172107255	1.9544658319718595	0.0506461518462992	1.0	0.5860562574610487	11	P46108,Q07666,P11802,Q8IZL8,P18031	5
Cytoprotection by hmox1	0.4435699377596853	1.9409958773573557	0.0522587774283105	1.0	0.5860562574610487	62	P09601,Q92530,P62191,P25789,P61289,P30519,Q9UL46,P25787,P20674,P49721,Q8TCT9,P00403,O00231,P43686,O43819,P28074,P13073,P28066,P28072	19
Peptide hormone metabolism	0.6537120306755451	1.933481842483492	0.0531768677640345	1.0	0.5860562574610487	12	Q8TAD4,Q15005,O75787,P67812	4
Apc c cdc20 mediated degradation of cyclin b	0.677275891035256	1.9186660056557336	0.055026616321661	1.0	0.5928946561298633	10	Q9UJX4,Q9UJX2,P06493,Q9UJX3	4
Metabolism of porphyrins	0.7589291752568939	1.874634552204662	0.0608430163438218	1.0	0.6170920523194597	7	P30519,P36551,P09601	3
Phase i functionalization of compounds	0.6417673945387663	1.868809247956731	0.0616493577710028	1.0	0.6170920523194597	12	O00170,O43169,Q15185,Q16850,P07099,P16435	6
Disorders of transmembrane transporters	0.4073154684639508	1.8503918852595536	0.0642570877382533	1.0	0.6196219174760144	72	P57740,Q92530,P35613,P62191,P25789,P61289,Q9UL46,Q99567,P25787,P49721,Q8NFH4,Q9BUN8,Q06323,Q9BW27,Q7Z3B4,O00231,P43686,Q9UBV2,Q12769,P28074,Q9BTX1,P28066,O75477,P28072	24
G1 s specific transcription	0.6711317855775127	1.824703550711288	0.0680457771639955	1.0	0.6387187684013687	9	Q9Y619,P31350,P00374	3
Synthesis of pa	0.7016318790441802	1.8134737445359017	0.0697587845575411	1.0	0.6387187684013687	8	Q8N2A8,Q9NPH0	2
Processing of smdt1	0.6653810880833768	1.7956288031967176	0.0725535718622083	1.0	0.6427598868590535	9	Q99623,Q10713,Q9Y4W6,Q9UJZ1	4
Switching of origins to a post replicative state	0.4395045420990965	1.7503547537906	0.080057118314732	1.0	0.6797302498420646	55	Q9UJX3,Q92530,P62191,P25789,P61289,Q9UL46,Q9UJX2,Q14566,P25787,P49721,P25205,Q06323,Q9UJX4,O00231,P43686,P28074,Q9Y619,P28066,P28072	19
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.7833105040962756	1.743101583028957	0.0813158721549114	1.0	0.6808401903514547	5	P12235,P12236,P05141	3
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1	0.8283569602998546	1.7380321503902247	0.0822051489091015	1.0	0.6808401903514547	4	P67812	1
Incretin synthesis secretion and inactivation	0.8283569602998546	1.7380321503902247	0.0822051489091015	1.0	0.6808401903514547	4	P67812	1
Heme degradation	0.990277806196062	1.7342142056187084	0.0828800833522838	1.0	0.6816402244328389	3	P09601	1
Rac2 gtpase cycle	0.4722698615637549	1.728906457556329	0.083825838146426	1.0	0.681716153600453	32	Q86XL3,Q14739,O15173,P42167,Q13505	5
Abc family proteins mediated transport	0.4443084734733841	1.712002469388775	0.0868962133863369	1.0	0.6832623036341519	49	P25787,O00231,P40855,P43686,Q92530,P49721,Q9UBV2,P62191,Q9BUN8,P25789,P61289,P28066,Q9UL46,Q06323,P28074,O75477,P28072	17
Recycling of eif2 gdp	0.7224663706320633	1.710354694693774	0.0872003034083443	1.0	0.6832623036341519	7	Q9NR50,Q13144	2
Ion homeostasis	0.6786228228065043	1.7027013095303072	0.0886239796921062	1.0	0.6832623036341519	8	Q12797,P16615	2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.6750071390839095	1.6851882493256365	0.0919522574469486	1.0	0.6832623036341519	8	Q9UJX4,Q9UJX2,Q9UJX3	3
Cardiac conduction	0.6419250301843855	1.6761690567776524	0.0937050833312651	1.0	0.6832623036341519	9	Q12797,P16615	2
Cellular response to chemical stress	0.3953358740491949	1.67309243931201	0.0943090997222086	1.0	0.6832623036341519	71	P09601,Q92530,P07237,P62191,P25789,P61289,P30519,Q9UL46,P25787,P20674,P49721,Q8TCT9,P00403,O00231,P43686,O43819,P28074,P13073,P28066,P28072	20
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling	0.7133374218069575	1.6688323868752994	0.095150602283867	1.0	0.6832623036341519	7	Q15418,P51812	2
Diseases associated with n glycosylation of proteins	0.805539638154013	1.6447592068241137	0.1000194776730432	1.0	0.6995013009295498	4	Q9BT22	1
Hedgehog ligand biogenesis	0.4435318198385555	1.6373506380385707	0.1015572259127346	1.0	0.6995013009295498	40	P25787,O00231,P43686,Q92530,P49721,Q9UBV2,P07237,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	14
Ire1alpha activates chaperones	0.5123977915411168	1.6313751459785415	0.1028111859202987	1.0	0.704543659859915	21	Q9HCU5,Q9NWM8,P43307,Q9Y5M8	4
Ub specific processing proteases	0.3960833958750491	1.5854661647479504	0.1128604585640118	1.0	0.7381429528458952	68	P21796,P25787,O00231,P43686,Q92530,P49721,Q15388,Q9Y277,P62191,P61289,P28066,Q9UL46,P45880,P45974,P28074,P28072,Q96K76	17
Selective autophagy	0.4623560840485919	1.577045065599143	0.1147851560020043	1.0	0.7381429528458952	29	P21796,Q15388,P08670,Q9NS69,O95140,Q8N4H5	6
Mitotic g1 phase and g1 s transition	0.3833504804681101	1.5645044073848022	0.1176991587448601	1.0	0.7424946930166411	72	Q92530,P62191,P25789,P61289,Q9UL46,Q14566,P25787,P00374,P49721,P25205,P11802,Q06323,P31751,O00231,P43686,P28074,P31350,Q9Y619,P28066,P28072	20
Iron uptake and transport	0.5279749043119237	1.5511112143907042	0.1208750341594921	1.0	0.7487013920982931	18	P09601	1
Rhog gtpase cycle	0.4509204346640337	1.5510011432586503	0.1209014099832799	1.0	0.7487013920982931	32	P50402,Q86XL3,Q14739,O15173,P42167	5
Transport of vitamins nucleosides and related molecules	0.6826181681213372	1.528051948159839	0.1264996405887632	1.0	0.7516744786367061	7	P12235,P12236,Q8TB61	3
Cdt1 association with the cdc6 orc origin complex	0.4304347795357285	1.5135530744636825	0.1301392303687047	1.0	0.7516744786367061	38	P25787,O00231,P43686,Q9Y619,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Creb phosphorylation	0.9390613171839508	1.498741953982262	0.133940588313365	1.0	0.7516744786367061	2	P51812	1
Ras processing	0.7236563111774166	1.4902359949999735	0.1361621950582532	1.0	0.7516744786367061	5	P49356	1
Piwi interacting rna pirna biogenesis	0.673483903413201	1.485902256848459	0.1373049765776341	1.0	0.7516744786367061	7	Q8N2A8,Q9Y2W6	2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.4207791081891647	1.4844467685952387	0.1376904351720309	1.0	0.7516744786367061	49	P25787,Q9UJX4,O00231,Q9UJX3,P43686,Q92530,P49721,P62191,P25789,P61289,P53350,Q9UL46,Q06323,P28066,P28074,Q9UJX2,P28072	17
Metabolism of cofactors	0.7120342061840904	1.4824360739369145	0.138224301329948	1.0	0.7516744786367061	6	O75208,Q9NZJ6,O75874,P00374	4
Recruitment of mitotic centrosome proteins and complexes	0.4487241295398728	1.466336490174187	0.1425566390616623	1.0	0.7516744786367061	29	O95684,Q9Y5B8,O75935,P61163,P07900,P06493,O43805,P53350,Q68CZ6,Q15154,P07437,Q13561,P41208	13
Methylation	0.7075266318687222	1.4628261426679663	0.1435149577044852	1.0	0.7516744786367061	6	P21964	1
Cytochrome p450 arranged by substrate type	0.9292202876608632	1.458871046298052	0.144600603535699	1.0	0.7516744786367061	2	Q16850	1
Orc1 removal from chromatin	0.418788313951391	1.4556469234648877	0.1454902493855536	1.0	0.7516744786367061	48	P25787,O00231,P43686,Q9Y619,Q92530,P49721,P25205,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072,Q14566	15
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip	0.923921271763814	1.4374076591940967	0.1506021937571913	1.0	0.7516744786367061	2	P67812	1
Synthesis secretion and deacylation of ghrelin	0.923921271763814	1.4374076591940967	0.1506021937571913	1.0	0.7516744786367061	2	P67812	1
Regulation of runx3 expression and activity	0.4230199202696582	1.4159206079132958	0.1567987505200647	1.0	0.7516744786367061	36	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Alpha oxidation of phytanate	0.7033857704691477	1.4034101862887236	0.160494557194883	1.0	0.7516744786367061	5	P51648	1
Acyl chain remodelling of pg	0.9148372445117324	1.4006294126897263	0.1613249207643647	1.0	0.7516744786367061	2	Q8NF37	1
Cross presentation of soluble exogenous antigens endosomes	0.415330767864004	1.3759499826071715	0.1688371191045241	1.0	0.7516744786367061	37	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Degradation of axin	0.415330767864004	1.3759499826071715	0.1688371191045241	1.0	0.7516744786367061	37	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Stabilization of p53	0.4145386900762967	1.3690853876472389	0.1709725853854549	1.0	0.7516744786367061	38	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
G1 s dna damage checkpoints	0.4136416545913667	1.361886816309459	0.1732336074403055	1.0	0.7516744786367061	39	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Metabolism of polyamines	0.4134129194961619	1.3587976762755962	0.1742107098791792	1.0	0.7516744786367061	38	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Regulation of hmox1 expression and activity	0.4088884212790519	1.3513872094898391	0.1765714288654145	1.0	0.7516744786367061	47	P25787,O00231,P09601,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,Q8TCT9,P28074,P28072	14
Unfolded protein response upr	0.4212245563332176	1.346269751497113	0.1782155372740814	1.0	0.7516744786367061	34	Q9Y5M8,Q9NWM8,P43307,O76024,Q9HCU5	5
Toll like receptor tlr1 tlr2 cascade	0.5112152886305973	1.345419147398638	0.1784899153054127	1.0	0.7516744786367061	16	P51812,Q9BQ95	2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.5302290403487905	1.3438107767043508	0.1790095837443601	1.0	0.7516744786367061	14	P07237,Q02818,O76024,O43852,Q07065	5
Cholesterol biosynthesis	0.5180639973965145	1.3266871423977835	0.184612195939962	1.0	0.7559874781981349	15	P37268,Q16850,P14324,Q9H2C2,Q14534,Q14739,O75845	7
Cyclin a cdk2 associated events at s phase entry	0.4081685797587123	1.3261290987327767	0.1847969391150996	1.0	0.7559874781981349	44	P25787,P31751,O00231,P43686,Q92530,P49721,P11802,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	14
Apc c mediated degradation of cell cycle proteins	0.3906567796369383	1.280062762544166	0.2005230635312933	1.0	0.7885719956625704	57	P25787,Q9UJX4,O00231,Q9UJX3,P43686,Q92530,P49721,P06493,P62191,P25789,P61289,P53350,Q9UL46,Q06323,P28066,P28074,Q9UJX2,P28072	18
Negative regulation of nmda receptor mediated neuronal transmission	0.6744979158772325	1.2791673072338032	0.2008381457654198	1.0	0.7885719956625704	5	P07196,Q14012,Q13555,P35609	4
Diseases of mitotic cell cycle	0.5355708523201992	1.2761169794629776	0.2019141702535614	1.0	0.7885719956625704	12	Q9UJX4,Q9UJX2,P11802,Q9UJX3	4
Regulation of pten stability and activity	0.4031060686721185	1.2703318756257895	0.2039664384153092	1.0	0.7885719956625704	42	P25787,P31751,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Scf skp2 mediated degradation of p27 p21	0.4028073341995428	1.2649183224652396	0.2059006085166019	1.0	0.7885719956625704	41	P25787,O00231,P43686,Q92530,P49721,P11802,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Gene silencing by rna	0.4021818122404936	1.2590582376555857	0.2080092973785796	1.0	0.7885719956625704	41	Q7Z3B4,P57740,Q9Y2W6,Q15631,Q92621,P30876,P07900,Q8N2A8,Q8NFH4,O75569,Q9BTX1,O15397,Q99567,Q12769,Q99598,Q9BW27	16
Egr2 and sox10 mediated initiation of schwann cell myelination	0.6687565915712061	1.2544305459346592	0.2096855557112125	1.0	0.7885719956625704	5	Q9NR77	1
Metabolism of fat soluble vitamins	0.8636879969708503	1.2534224518842365	0.2100520047955116	1.0	0.7885719956625704	3	Q8N0U8,Q6NUM9	2
Visual phototransduction	0.7106269631413504	1.252222622926912	0.2104887547376175	1.0	0.7885719956625704	4	P49356,Q6NUM9	2
Degradation of gli1 by the proteasome	0.4012932447580986	1.2479360150127363	0.2120544901888421	1.0	0.7885719956625704	39	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Metabolism of steroid hormones	0.6577467101972	1.2450262623502322	0.2131220967775227	1.0	0.7885719956625704	6	Q53GQ0,O95772	2
Asymmetric localization of pcp proteins	0.4002312688057945	1.23784618083855	0.2157731012098716	1.0	0.7885719956625704	38	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Postmitotic nuclear pore complex npc reformation	0.4634496301698951	1.225708031979535	0.220308566572575	1.0	0.7885719956625704	20	Q7Z3B4,P57740,Q92621,Q8NFH4,Q92973,Q9BTX1,Q12769,Q9BW27	8
Transcriptional regulation by ventx	0.5360046945819618	1.2218669487320073	0.221757945972902	1.0	0.7885719956625704	11	Q9UJX4,Q9UJX2,Q9HCE1,Q9UJX3	4
Activation of nmda receptors and postsynaptic events	0.4704698875970982	1.2204010696794882	0.2223128720633211	1.0	0.7885719956625704	19	Q15418,Q9BVA1,Q14012,P52292,P10644,P07196,Q13555,P51812,Q13885	9
Toll like receptor 9 tlr9 cascade	0.4838140369292592	1.2134934442859386	0.2249412192994637	1.0	0.7885719956625704	17	P51812,Q9BQ95	2
Peroxisomal lipid metabolism	0.5434740941533066	1.2105069389604053	0.2260844297690982	1.0	0.7885719956625704	10	P51648,Q15067,Q9BY49,O43808	4
Regulation of ras by gaps	0.3967008654059465	1.2053120452978248	0.2280828613195042	1.0	0.7885719956625704	38	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Degradation of dvl	0.3967008654059465	1.2053120452978248	0.2280828613195042	1.0	0.7885719956625704	38	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Regulation of mrna stability by proteins that bind au rich elements	0.3805352980158955	1.2043111808810656	0.2284693267714295	1.0	0.7885719956625704	59	Q01105,P25787,O00231,P43686,Q92530,P49721,P62191,Q92945,P25789,P61289,P28066,Q9UL46,Q14103,Q06323,P28074,P28072	16
Initiation of nuclear envelope ne reformation	0.4818386524833263	1.2006343090432774	0.2298930862510708	1.0	0.7885719956625704	17	Q86XL3,P42167,Q14739	3
Antigen processing cross presentation	0.3911387292874458	1.200606718548931	0.2299037936516355	1.0	0.7885719956625704	50	O75396,P25787,P61619,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072,P10321	15
E3 ubiquitin ligases ubiquitinate target proteins	0.514578039867079	1.2004082684663857	0.2299808191968044	1.0	0.7885719956625704	13	Q9BUN8	1
Ra biosynthesis pathway	0.8633610900832689	1.1931359253135772	0.2328161437683391	1.0	0.7885719956625704	2	Q8NBN7	1
Hedgehog on state	0.3950821736946698	1.1924186081226398	0.2330971475090655	1.0	0.7885719956625704	41	Q2M1P5,P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.5490095032464568	1.1914402511426858	0.233480799318559	1.0	0.7885719956625704	9	Q9UJX4,Q9UJX2,Q9UJX3	3
Recruitment of numa to mitotic centrosomes	0.4052491167781656	1.1834127484290349	0.2366456073082472	1.0	0.7920820598794871	33	O95684,Q9Y5B8,O75935,P61163,P07900,P06493,O43805,O94927,P53350,Q68CZ6,Q15154,P07437,Q13561,Q13885,P41208	15
Downstream signaling events of b cell receptor bcr	0.3934080074490199	1.1787069395655478	0.2385148913798735	1.0	0.7936385678527137	42	P25787,O00231,P62942,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Activation of nima kinases nek9 nek6 nek7	0.6494762314109628	1.1713299952033085	0.2414661591215297	1.0	0.7936385678527137	5	P53350,P06493,O95067	3
Phosphorylation of emi1	0.6891987466991135	1.1632815215654375	0.2447153003450664	1.0	0.7999168413216455	4	P06493	1
Sulfur amino acid metabolism	0.5430535380753531	1.1599357494531122	0.2460749662235786	1.0	0.8004848298839304	9	Q9UBX3,Q13126	2
Deadenylation dependent mrna decay	0.4023683656688802	1.158324448046538	0.2467316580522691	1.0	0.8006916787753926	33	Q6PGP7,Q86TB9,Q969T7,Q92600,P23588,Q96C86,Q5RKV6,Q9NZN8,O95628,Q5TAX3	10
Gastrin creb signalling pathway via pkc and mapk	0.6869449520719597	1.153937455312728	0.2485258118599829	1.0	0.8021769062170993	4	P51812	1
Mitotic g2 g2 m phases	0.3532872499321822	1.13631717144813	0.255823846783312	1.0	0.8089622792790934	88	O95684,O75935,Q92530,P62191,P25789,P61289,Q9UL46,P41208,P25787,P49721,Q06323,P07437,Q13561,O00231,Q9Y5B8,P61163,P07900,P06493,P43686,Q99640,Q15154,P28074,P53350,O43805,P28066,Q68CZ6,P28072,Q13885,O94927	29
Cellular response to hypoxia	0.3890785892024287	1.135901359226649	0.2559978493909871	1.0	0.8089622792790934	41	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,Q9NWT6,P28074,P28072	13
The role of gtse1 in g2 m progression after g2 checkpoint	0.3844881710665569	1.1338989521836695	0.2568369367057916	1.0	0.8089622792790934	50	Q9BVA1,Q92530,P62191,P25789,P61289,Q9UL46,P25787,P49721,Q06323,O00231,P43686,P07900,P06493,P28074,P53350,P68371,P51665,P62333,P28066,P28072,Q13885	21
Biological oxidations	0.3882412083009364	1.1267321601105378	0.2598557408014101	1.0	0.8102221802220723	39	O60701,O00170,Q8TB61,P78417,O43169,Q15185,Q16850,P21964,P07099,Q99735,P16435	11
Auf1 hnrnp d0 binds and destabilizes mrna	0.3872523508958969	1.1203446435817772	0.2625669246020636	1.0	0.8102221802220723	42	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,Q14103,P28074,P28072	13
Transcriptional regulation by runx3	0.3874502140858478	1.1196015920466094	0.2628835768506568	1.0	0.8102221802220723	40	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Nuclear events kinase and transcription factor activation	0.5264714286127621	1.118221861252672	0.263472249716659	1.0	0.8102221802220723	10	Q15418,P51812	2
Tysnd1 cleaves peroxisomal proteins	0.6771753832442629	1.1134712229075667	0.265506100884046	1.0	0.8109257008398828	4	O00116	1
Ras activation upon ca2 influx through nmda receptor	0.6742424242424321	1.101336835424331	0.2707500851040949	1.0	0.8109257008398828	4	P35609,P07196,Q13555	3
Long term potentiation	0.6742424242424321	1.101336835424331	0.2707500851040949	1.0	0.8109257008398828	4	P35609,P07196,Q13555	3
Unblocking of nmda receptors glutamate binding and activation	0.6742424242424321	1.101336835424331	0.2707500851040949	1.0	0.8109257008398828	4	P35609,P07196,Q13555	3
G2 m dna replication checkpoint	0.6738231073560155	1.0996026240582255	0.2715052981623285	1.0	0.8109257008398828	4	P06493,Q99640	2
Hiv transcription initiation	0.6227309251543203	1.091158640992089	0.2752030831950869	1.0	0.8147459699854547	6	P30876,Q92804	2
Ubiquinol biosynthesis	0.8330809992429968	1.0725070988287844	0.2834923271867318	1.0	0.8283866703508397	2	O75208	1
Anchoring of the basal body to the plasma membrane	0.4024099967218584	1.0691584512333008	0.2849982770858932	1.0	0.8309884969027124	28	O95684,O43805,O75935,P61163,P07900,P06493,P53350,Q68CZ6,Q15154,P07437,Q13561,P41208	12
Protein ubiquitination	0.4248514931512864	1.0638187799173304	0.2874108021097707	1.0	0.8344184577380441	22	O75381,Q9BUN8	2
Rhoa gtpase cycle	0.3804403276771529	1.0548732972042654	0.2914832762849457	1.0	0.8396397416406357	38	P30519,O15173,P42167	3
Signaling by the b cell receptor bcr	0.3788196910900393	1.0446808139102692	0.2961705151102327	1.0	0.8470978716076571	44	P25787,O00231,P62942,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Negative regulation of notch4 signaling	0.3780411421256217	1.0313018795862414	0.302399277198949	1.0	0.8579151592322765	40	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Gamma carboxylation hypusine formation and arylsulfatase activation	0.5100930219084661	1.0292121727605397	0.3033799834229618	1.0	0.8579151592322765	10	P38435,O43681,P13639,O60725	4
Fceri mediated nf kb activation	0.377041668008763	1.0250309813290457	0.3053485695001967	1.0	0.8585627701441352	43	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Runx1 regulates transcription of genes involved in differentiation of hscs	0.3759397279748852	1.0115534048692412	0.3117516341862767	1.0	0.8590270848116947	40	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,Q03164,P28072	13
Ptk6 regulates proteins involved in rna processing	0.8175624526873572	1.0113537641863006	0.311847142054706	1.0	0.8590270848116947	2	Q07666	1
Autophagy	0.3734538254920598	0.9882916487827752	0.3230098342321001	1.0	0.8776700197249578	41	P21796,Q15388,P08670,Q9NS69,O95140,Q8N4H5	6
Tnfr2 non canonical nf kb pathway	0.373028137644208	0.9865556077662476	0.3238605418164397	1.0	0.8776700197249578	43	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Synthesis of pe	0.7909355504675661	0.9797393706115282	0.3272147866984096	1.0	0.8811315798249971	3	P35790	1
Interleukin 4 and interleukin 13 signaling	0.4823647523832138	0.9713272011516448	0.331385367518719	1.0	0.8811315798249971	12	P09601	1
Interleukin 17 signaling	0.4818821887156335	0.9685606019798448	0.3327644685668132	1.0	0.8811315798249971	12	P51812	1
Pregnenolone biosynthesis	0.6413581954702842	0.9659662761598248	0.3340610563509698	1.0	0.8811315798249971	4	O95772	1
Regulation of tp53 expression and degradation	0.5298919221485924	0.9657339827238656	0.3341773102743692	1.0	0.8811315798249971	8	P06493,P31751,P30154	3
Toll like receptor cascades	0.4112840403298122	0.9630976166527802	0.3354985377238204	1.0	0.8812871741969432	22	Q15418,P51812,Q9BQ95	3
Transcriptional regulation by runx2	0.3663872554394022	0.9588697794793868	0.3376243507126051	1.0	0.883319522213211	51	P25787,P31751,O00231,P43686,Q92530,P49721,P11802,P62191,P25789,P61289,P28066,Q9UL46,Q06323,P28074,P28072,Q96PK6	16
Mrna decay by 3 to 5 exoribonuclease	0.478562034183375	0.9495308404732754	0.3423506941945469	1.0	0.8843747721467847	12	Q6PGP7,Q96C86,Q969T7	3
Constitutive signaling by akt1 e17k in cancer	0.6367870601348188	0.9472809333057508	0.343495643910102	1.0	0.8843747721467847	4	P42345,P31751	2
Rhod gtpase cycle	0.3916713093934478	0.945977033701451	0.3441603002817548	1.0	0.8843747721467847	25	P50402,O15173,P42167,Q14739	4
Synthesis of very long chain fatty acyl coas	0.5570188160340136	0.9424294472862562	0.3459728167615532	1.0	0.8850492291297897	7	Q9NZ01	1
Wnt ligand biogenesis and trafficking	0.5877999579428159	0.9381705788679072	0.3481567554796638	1.0	0.8850492291297897	6	Q5T9L3,O75436,Q9Y3A6	3
Mapk targets nuclear events mediated by map kinases	0.5554153251993271	0.9349601373175122	0.3498088431483972	1.0	0.8850492291297897	7	P51812	1
Erk mapk targets	0.5554153251993271	0.9349601373175122	0.3498088431483972	1.0	0.8850492291297897	7	P51812	1
Unwinding of dna	0.5235938439617586	0.9342929976634328	0.3501527753794151	1.0	0.8850492291297897	8	Q14566	1
Apc cdc20 mediated degradation of nek2a	0.48383321497192	0.9309364180227834	0.3518864547970035	1.0	0.8850492291297897	11	Q9UJX4,Q9UJX2,Q9UJX3	3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.48383321497192	0.9309364180227834	0.3518864547970035	1.0	0.8850492291297897	11	Q9UJX4,Q9UJX2,Q9UJX3	3
Deadenylation of mrna	0.4600492921398101	0.9210994036514732	0.3569985315677311	1.0	0.8875279032007589	14	Q5TAX3,Q92600,Q9NZN8	3
Signaling by hedgehog	0.3590952015779328	0.9204493049375608	0.3573380133067989	1.0	0.8875279032007589	55	Q2M1P5,Q9BVA1,P10644,Q92530,P07237,P62191,P25789,P61289,Q9UL46,P25787,P49721,Q06323,P63208,O00231,P43686,Q9UBV2,P28074,P68371,P51665,P62333,P28066,P28072,Q13885	23
Small interfering rna sirna biogenesis	0.7743279060961736	0.9184280264172616	0.3583948235143448	1.0	0.8875279032007589	3	Q15631,O75569	2
Deubiquitination	0.3320836592851472	0.9094655407754508	0.3631044393369707	1.0	0.8875279032007589	83	P21796,Q92530,P62191,P25789,P14735,P61289,Q9UL46,P25787,P49721,P45880,Q06323,Q9Y3E5,Q96FW1,Q9Y5K5,O00231,P43686,P06493,P28074,Q15388,Q9Y277,Q7Z434,P54727,P28066,Q8NB78,P45974,P28072,Q96K76	27
Mitochondrial translation	0.3640648694781019	0.9077272538443528	0.3640223410364225	1.0	0.8875279032007589	46	Q8TAE8,Q15070,Q7Z7H8	3
Signaling by notch4	0.3646715777279345	0.9054196121577184	0.365243129585056	1.0	0.8875279032007589	42	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Dectin 1 mediated noncanonical nf kb signaling	0.3639982906791419	0.8999300525738954	0.3681574758218968	1.0	0.8875279032007589	43	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Hedgehog off state	0.3608026847480921	0.8951468845392841	0.3707085739538693	1.0	0.8889104348805038	50	Q2M1P5,Q9BVA1,P10644,Q92530,P62191,P25789,P61289,Q9UL46,P25787,P49721,Q06323,P63208,O00231,P43686,P28074,P68371,P51665,P62333,P28066,P28072,Q13885	21
Assembly and cell surface presentation of nmda receptors	0.4845624436018648	0.8907037126287034	0.3730881425327337	1.0	0.891449544104762	10	Q9BVA1,P07196,P35609,Q13555,Q15334,Q13885,P68371	7
Regulation of runx2 expression and activity	0.3618095262267011	0.878931539986952	0.3794383962879388	1.0	0.8987296797673759	43	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Intra golgi traffic	0.5423280725934247	0.8741485336426451	0.3820373696325059	1.0	0.8987296797673759	7	O00461	1
Aryl hydrocarbon receptor signalling	0.7605026609085404	0.8678946009815767	0.3854520348673804	1.0	0.8987296797673759	3	O00170	1
Stimuli sensing channels	0.5405356880199683	0.8658441792514595	0.3865756180267761	1.0	0.8987296797673759	7	Q12797	1
Constitutive signaling by overexpressed erbb2	0.7598328690392022	0.8654595192689937	0.3867866251443299	1.0	0.8987296797673759	3	P07900	1
Rsk activation	0.7573415218479259	0.8564133331473472	0.3917691922726503	1.0	0.9071842359658282	3	P51812	1
Translation of sars cov 2 structural proteins	0.4482981556538733	0.8503887500255422	0.3951089886929968	1.0	0.9086833641150692	14	Q10472,P46977	2
Aurka activation by tpx2	0.3753845204770005	0.8468402756657883	0.3970841557056022	1.0	0.9116728064669438	28	O95684,O43805,O75935,P61163,P07900,P06493,P53350,Q68CZ6,Q15154,P07437,Q13561,P41208	12
E2f enabled inhibition of pre replication complex formation	0.7489957714751556	0.8262447928091979	0.4086652435428866	1.0	0.9194427577655038	3	Q9Y619	1
Senescence associated secretory phenotype sasp	0.4230357974486176	0.8171622968329649	0.4138356857350209	1.0	0.9194427577655038	17	Q9UJX4,Q15418,Q9UJX3,P11802,Q9UJX2,P51812	6
Regulation of signaling by cbl	0.6043421233738341	0.8160510685866488	0.4144709281004155	1.0	0.9194427577655038	4	P62993,P46108	2
Circadian clock	0.4931601685826103	0.7833173136025227	0.4334407985972621	1.0	0.934736546495693	8	P43490	1
Rac3 gtpase cycle	0.3652668456836752	0.7753553233816364	0.4381297269397599	1.0	0.9404723514684792	29	P50402,O15173,P42167,Q14739	4
Tcr signaling	0.349875947296848	0.7752830509630353	0.4381724223445031	1.0	0.9404723514684792	48	P25787,O00231,P43686,Q92530,P49721,P62191,Q13153,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Signaling by interleukins	0.3342455680273725	0.7744687202907593	0.4386536588439265	1.0	0.9404723514684792	102	P09601,Q92530,P07237,P62191,P25789,P61289,Q9UL46,O14979,Q07820,P25787,P52597,Q15418,P46108,Q13126,P49721,Q99439,O00231,O00170,P43686,P08670,P22626,P28074,P51812,P78417,P27824,P28066,P28072	27
Nuclear envelope ne reassembly	0.3500686661577534	0.7706889196750341	0.4408913411645314	1.0	0.9417773901457556	46	P50402,P57740,Q9BVA1,Q7Z3B4,Q86XL3,Q13885,Q92621,P06493,Q8NFH4,Q92973,Q9BTX1,P42167,Q12769,P53990,Q14739,Q9BW27	16
Formation of the early elongation complex	0.4539350072550179	0.7652648722990295	0.4441138370313462	1.0	0.9441790236099488	11	Q8IXH7,P30876	2
E2f mediated regulation of dna replication	0.4604514013000247	0.7609072933207789	0.4467124420114094	1.0	0.9467218158797532	10	Q9Y619,P06493,P30154	3
Formation of incision complex in gg ner	0.4553851307673364	0.733852173238587	0.4630388386050816	1.0	0.9676429556739248	10	P41208	1
Regulation of plk1 activity at g2 m transition	0.3527702769377794	0.7251788369729408	0.468342324219245	1.0	0.9676429556739248	33	O95684,O43805,O75935,P61163,P07900,P06493,P53350,Q68CZ6,Q15154,P07437,Q13561,P41208	12
Beta catenin independent wnt signaling	0.3450786188749518	0.7244627325059002	0.4687816987138145	1.0	0.9676429556739248	47	P25787,Q9HCE1,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Camk iv mediated phosphorylation of creb	0.7414837244511703	0.7223651685801099	0.4700699958850509	1.0	0.9676429556739248	2	P52292	1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde	0.7414837244511703	0.7223651685801099	0.4700699958850509	1.0	0.9676429556739248	2	P52292	1
Vitamin c ascorbate metabolism	0.7407267221801619	0.7196121187099798	0.471763848391808	1.0	0.9693777706680988	2	P78417	1
Insulin processing	0.5082619110532085	0.7177455790861159	0.4729141741627665	1.0	0.9702646430391106	7	Q96KP1,Q8TAD4,O60645,P33176	4
Antigen presentation folding assembly and peptide loading of class i mhc	0.4250012286341763	0.7112884518487883	0.4769055062558807	1.0	0.9766209873588316	14	P27824,Q9NZ08,P10321	3
Intra golgi and retrograde golgi to er traffic	0.3118088112170447	0.7044907633395632	0.4811272002496289	1.0	0.9784990620967902	77	O75396,P62820,O00461,Q9P2W9,P33176,O75935,O15260,P52732,Q8N2H4,P40616,Q10472,Q13561,Q13190,P24390	14
Neuronal system	0.3431970821115603	0.7010301378896145	0.4832842072394689	1.0	0.9784990620967902	44	Q15418,O95197,P51812,P21964	4
Translation of sars cov 1 structural proteins	0.5325610819974346	0.7006868415695597	0.4834984696142945	1.0	0.9784990620967902	6	Q10472	1
C type lectin receptors clrs	0.3417967563312294	0.6989809688083678	0.4845639243620554	1.0	0.9784990620967902	49	P25787,O00231,P43686,Q92530,P49721,P62191,Q13153,P25789,P61289,P28066,Q9UL46,P28074,P28072	13
Mapk6 mapk4 signaling	0.3416501633039345	0.6937794464040616	0.4878205341852692	1.0	0.9784990620967902	48	P25787,Q9HCE1,O00231,P43686,Q92530,P49721,P62191,Q13153,P25789,P61289,P28066,Q9UL46,Q06323,P28074,P28072	15
Signaling by notch	0.3391547882350214	0.6879773596948866	0.4914670387694502	1.0	0.9805192907294524	52	P25787,Q9HCE1,O00231,P43686,Q92530,P49721,Q9UBV2,P62191,P25789,P61289,P28066,Q9UL46,P67809,P28074,P28072,P16615	16
Interleukin 1 signaling	0.34132338433572	0.6875880008875368	0.4917122665361773	1.0	0.9805192907294524	47	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Transport of bile salts and organic acids metal ions and amine compounds	0.708767412278366	0.6843038835558863	0.4937832951749885	1.0	0.9811824652646728	3	Q8TAD4	1
Noncanonical activation of notch3	0.7263436790310327	0.6678992677149331	0.504197894870952	1.0	0.9811824652646728	2	P67809	1
Pcp ce pathway	0.3390714308691315	0.6621138090018087	0.5078982865471509	1.0	0.9811824652646728	45	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Interleukin 12 family signaling	0.3499969971716645	0.6605167608104304	0.5089222662239079	1.0	0.981492942003251	30	P52597,Q13126,P78417,P07237,P27824,Q9UL46,O14979,P22626	8
Synthesis of pips at the golgi membrane	0.5281653418774406	0.6588121914589926	0.5100163775588042	1.0	0.9821998711902792	5	Q10713,Q9NTJ5	2
Uch proteinases	0.3377926856982652	0.6497839207538784	0.5158318066608696	1.0	0.9860329496358086	45	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,Q06323,P28074,P28072	13
Clec7a dectin 1 signaling	0.3367788986449871	0.6430783861966204	0.5201732383559392	1.0	0.9893758522464244	47	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Activation of bad and translocation to mitochondria	0.4895714827455362	0.6337050245412474	0.5262733452433852	1.0	0.9922751621209078	7	P27348,P61981,P31751,P62258,Q04917,P31946	6
Signaling by hippo	0.5564393939394026	0.6290428596342776	0.529320997334326	1.0	0.9952237694306532	4	Q07157,P62258,P31946	3
Phase 0 rapid depolarisation	0.714988644965931	0.6279315107086126	0.5300488075708443	1.0	0.9952237694306532	2	Q13555	1
Wax and plasmalogen biosynthesis	0.6906474820143862	0.6226815053674056	0.5334938386551429	1.0	0.9997700331072024	3	O00116,O15228	2
Interleukin 12 signaling	0.3488435884559376	0.6219857248030237	0.5339512547187355	1.0	0.9997700331072024	27	P52597,Q13126,P78417,P07237,Q9UL46,O14979,P22626	7
Degradation of beta catenin by the destruction complex	0.3344615256766838	0.6204399847439844	0.5349681546121801	1.0	1.0	47	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Myd88 independent tlr4 cascade	0.3963171664513124	0.6169776162492945	0.5372494899364697	1.0	1.0	16	P51812	1
Met activates ras signaling	0.686759240625667	0.6096806369079256	0.542073383659285	1.0	1.0	3	Q96P70	1
Met receptor recycling	0.6856896319578856	0.6061188906344058	0.5444358076427882	1.0	1.0	3	P46108	1
Intrinsic pathway of fibrin clot formation	0.7081756245268696	0.6043461940975903	0.5456135003643443	1.0	1.0	2	Q07021	1
Formation of fibrin clot clotting cascade	0.7081756245268696	0.6043461940975903	0.5456135003643443	1.0	1.0	2	Q07021	1
Fc epsilon receptor fceri signaling	0.331643931273174	0.6017994027841151	0.547307672716344	1.0	1.0	50	Q92530,P62191,P25789,P61289,Q9UL46,P25787,Q13177,P49721,Q13153,Q06323,P63208,O00231,P43686,P28074,P51665,P62333,P62993,P28066,P28072	19
Mapk family signaling cascades	0.307969836658565	0.6001218253155632	0.5484250480827875	1.0	1.0	83	Q92530,P62191,P61289,Q9UL46,P25787,Q9HCE1,Q96P70,P49356,P07196,P49721,Q13153,O60725,O00231,P43686,P28074,Q9Y4G8,Q99956,P28066,P28072	19
Interactions of vpr with host cellular proteins	0.3378058592137414	0.5826769262197855	0.5601108089621625	1.0	1.0	32	Q7Z3B4,P57740,P12235,Q8NFH4,Q9BTX1,P12236,Q12769,P05141,Q9BW27	9
Dna replication pre initiation	0.3240700766080743	0.579691708552079	0.5621225357682695	1.0	1.0	58	P25787,O00231,P43686,Q9Y619,Q92530,P49721,P25205,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072,Q14566	15
Interleukin 1 family signaling	0.329661349293475	0.5785200638552304	0.5629130554547008	1.0	1.0	49	P25787,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	12
Gpcr ligand binding	0.4484325043563396	0.5671680039973825	0.5706000440671155	1.0	1.0	8	P05067,Q9NZJ7,P42892,Q9NRV9	4
Nrif signals cell death from the nucleus	0.6960635881907603	0.5632056360445165	0.5732948655062917	1.0	1.0	2	Q92542	1
Cd28 dependent pi3k akt signaling	0.6945495836487466	0.5581375852039526	0.5767504370898826	1.0	1.0	2	P31751	1
Prevention of phagosomal lysosomal fusion	0.536742424242431	0.5555847986884733	0.5784947256667716	1.0	1.0	4	P51149,P20339,Q9H267	3
Transcription of the hiv genome	0.3761066364641082	0.5465774973406887	0.5846690322806332	1.0	1.0	18	Q8IXH7,P30876,Q92804	3
Metabolism of steroids	0.3264582922247414	0.5422486592205836	0.5876472185225003	1.0	1.0	43	P37268,P38435,P30536,P22059,Q16850,Q53GQ0,O95772,P14324,Q9H2C2,Q14534,Q14739	11
Aquaporin mediated transport	0.6641600558222052	0.5358635843886433	0.5920528336841202	1.0	1.0	3	Q99797	1
Golgi cisternae pericentriolar stack reorganization	0.4230955939179667	0.5347823371578682	0.5928003781379829	1.0	1.0	9	P53350,P06493,P62820,P61019	4
Synthesis of dna	0.2996212949961802	0.5301361877309617	0.5960175104169605	1.0	1.0	79	Q9UJX3,Q92530,P62191,P25789,P61289,Q9UL46,Q9UJX2,Q14566,P25787,P49721,P25205,Q06323,Q9UJX4,O00231,P43686,P28074,Q9Y619,P28066,P28072	19
Nuclear pore complex npc disassembly	0.3349152096786045	0.5271433010719235	0.5980940788681175	1.0	1.0	29	Q7Z3B4,P57740,Q92621,P06493,O95067,Q8NFH4,Q8N1F7,Q8TD19,P52948,Q9BTX1,Q8TEM1,Q99567,Q12769,Q9NRG9,Q5SRE5,Q9BW27	16
Cilium assembly	0.3233215091826647	0.5228378874292853	0.6010870714289509	1.0	1.0	51	Q9BVA1,O95684,O75935,P41208,A0AVF1,A6NIH7,P07437,Q13561,Q10713,P61163,P07900,P06493,Q15154,P53350,Q96KP1,O43805,Q68CZ6,Q13885,O94927	19
Alpha linolenic omega3 and linoleic omega6 acid metabolism	0.5268939393939492	0.5198254570831645	0.6031852344136166	1.0	1.0	4	P51659,P33121,Q15067	3
Transport of the slbp dependant mature mrna	0.3338860660263466	0.5109529819086027	0.6093839804680643	1.0	1.0	28	Q7Z3B4,P57740,Q92621,Q8NFH4,Q9BTX1,Q9UBU9,Q99567,Q12769,Q9BW27	9
Regulation of localization of foxo transcription factors	0.4892004547177046	0.5056810857945147	0.6130805483026407	1.0	1.0	5	P27348,P61981,P31751,P31946	4
Fgfr2 alternative splicing	0.4056070022331451	0.5052200771686643	0.6134042703436915	1.0	1.0	11	P52597,P31943	2
Regulation of kit signaling	0.6782740348220995	0.5047753730938532	0.6137166147203845	1.0	1.0	2	P62993	1
Abacavir transport and metabolism	0.6778955336865962	0.5035597426445179	0.6145707881460911	1.0	1.0	2	P08183	1
Runx1 regulates expression of components of tight junctions	0.6733535200605552	0.4890661373810303	0.6247948742498166	1.0	1.0	2	Q16625	1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.3332247057882959	0.4884776288726997	0.6252115677932366	1.0	1.0	25	P52597,Q13126,P78417,Q9UL46,O14979,P22626	6
Signaling by erbb2 ecd mutants	0.5146526297306531	0.4764005187834808	0.6337890651481715	1.0	1.0	4	P07900	1
Signaling by erbb2 in cancer	0.5146526297306531	0.4764005187834808	0.6337890651481715	1.0	1.0	4	P07900	1
Regulation of glucokinase by glucokinase regulatory protein	0.3305639457897137	0.4683881412911049	0.6395070468877657	1.0	1.0	25	Q7Z3B4,P57740,Q92621,Q8NFH4,Q8N1F7,Q9BTX1,Q99567,Q12769,Q9NRG9,Q9BW27	10
Sumoylation of sumoylation proteins	0.3305639457897137	0.4683881412911049	0.6395070468877657	1.0	1.0	25	Q7Z3B4,P57740,Q92621,Q8NFH4,Q8N1F7,Q9BTX1,Q99567,Q12769,Q9NRG9,Q9BW27	10
Sumoylation of ubiquitinylation proteins	0.3305639457897137	0.4683881412911049	0.6395070468877657	1.0	1.0	25	Q7Z3B4,P57740,Q92621,Q8NFH4,Q8N1F7,Q9BTX1,Q99567,Q12769,Q9NRG9,Q9BW27	10
Maturation of sars cov 2 nucleoprotein	0.5117424242424309	0.4662559159089079	0.6410323295951623	1.0	1.0	4	P48729,Q99873,P49841	3
Collagen biosynthesis and modifying enzymes	0.4081753903950348	0.4616065150781012	0.644363521641681	1.0	1.0	9	P13674,P07237	2
Sumoylation of rna binding proteins	0.32515338985743	0.4573676851534271	0.6474067871801532	1.0	1.0	30	Q7Z3B4,P57740,Q92621,Q8NFH4,P07910,Q9BTX1,Q99567,Q12769,P61978,Q9BW27	10
Abortive elongation of hiv 1 transcript in the absence of tat	0.4011613444390977	0.4531778183722714	0.6504207035940841	1.0	1.0	10	Q8IXH7	1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis	0.6536714610143775	0.4283659931172732	0.6683846793884463	1.0	1.0	2	O00767	1
Platelet aggregation plug formation	0.4662051444488586	0.4205063740530266	0.6741155739662656	1.0	1.0	5	P46108,P18031	2
Integrin signaling	0.4662051444488586	0.4205063740530266	0.6741155739662656	1.0	1.0	5	P46108,P18031	2
Antigen activates b cell receptor bcr leading to generation of second messengers	0.6498864496593433	0.4171064213247256	0.6766005682988492	1.0	1.0	2	P62993	1
Peptide ligand binding receptors	0.4353526624904236	0.4021197165518009	0.6875959230211837	1.0	1.0	7	Q9NZJ7,P42892,Q9NRV9	3
Class a 1 rhodopsin like receptors	0.4353526624904236	0.4021197165518009	0.6875959230211837	1.0	1.0	7	Q9NZJ7,P42892,Q9NRV9	3
Recycling pathway of l1	0.3484998822190909	0.4006133772108785	0.6887047952020708	1.0	1.0	19	Q15418,P51812	2
Signaling by ntrks	0.3199316642256496	0.3925993488943543	0.6946154205298467	1.0	1.0	26	Q15418,P51812,P50570	3
Heme biosynthesis	0.4881536476967369	0.3868466305760104	0.6988697534220067	1.0	1.0	4	P36551	1
Transcriptional regulation by e2f6	0.4307925673113397	0.3837746117655855	0.7011455067108521	1.0	1.0	7	P31350,Q99496,P45973,Q09028,Q13185,Q15022	6
Signaling by egfr in cancer	0.4548493987858638	0.3802326273440634	0.7037727417029833	1.0	1.0	5	P62993,P07900	2
Constitutive signaling by ligand responsive egfr cancer variants	0.4548493987858638	0.3802326273440634	0.7037727417029833	1.0	1.0	5	P62993,P07900	2
Constitutive signaling by egfrviii	0.4548493987858638	0.3802326273440634	0.7037727417029833	1.0	1.0	5	P62993,P07900	2
Sensory perception	0.349243955615142	0.3790375207249625	0.7046600015440299	1.0	1.0	18	P49356,Q6NUM9	2
Retrograde transport at the trans golgi network	0.3746107552397119	0.3755173719391212	0.7072757292132659	1.0	1.0	12	Q8N2H4	1
Slc transporter disorders	0.3148085197653575	0.3753520662387505	0.7073986486950607	1.0	1.0	30	Q7Z3B4,P57740,P08195,Q92621,P35613,Q8NFH4,Q9BTX1,Q99567,Q12769,Q9BW27	10
Ovarian tumor domain proteases	0.4447027708788769	0.3535720421413361	0.72365962973723	1.0	1.0	6	P06493,Q7Z434	2
Signaling by flt3 fusion proteins	0.5954939933054262	0.3344207015010536	0.7380621202250721	1.0	1.0	3	Q14789	1
Map3k8 tpl2 dependent mapk1 3 activation	0.4666666666666728	0.3194256027907408	0.7494037987021518	1.0	1.0	4	P63208,O15111,Q13616	3
Signaling by type 1 insulin like growth factor 1 receptor igf1r	0.434467549336925	0.3113969278258643	0.7554988891307044	1.0	1.0	5	O14654,P31751	2
Nr1h2 and nr1h3 mediated signaling	0.4338363010171636	0.3093417135294732	0.7570616031314032	1.0	1.0	5	Q9HCE1,Q8NB78	2
Export of viral ribonucleoproteins from nucleus	0.3064453731069788	0.2967320775619391	0.7666710650694468	1.0	1.0	27	Q7Z3B4,P57740,Q92621,Q8NFH4,Q8N1F7,Q9BTX1,Q99567,Q12769,Q9NRG9,Q9BW27	10
Depolymerisation of the nuclear lamina	0.3718284984603616	0.2932782467766202	0.7693094795423971	1.0	1.0	9	P42167	1
Rab geranylgeranylation	0.3379480021352537	0.2916217263186032	0.7705758619506091	1.0	1.0	17	Q969Q5,P61019	2
Viral messenger rna synthesis	0.3040728215322398	0.2872454998552553	0.773924349690676	1.0	1.0	29	Q7Z3B4,P57740,Q92621,P30876,Q8NFH4,Q9BTX1,Q99567,Q12769,Q9BW27	9
Transmission across chemical synapses	0.2959711690310231	0.2799721996484816	0.7794988337509487	1.0	1.0	36	Q15418,P51812,P21964	3
Tnf signaling	0.4240242516104632	0.2780318784454033	0.7809878876657366	1.0	1.0	5	Q96BN8,Q8TCT8,O15111,P63244	4
Regulation of tnfr1 signaling	0.4240242516104632	0.2780318784454033	0.7809878876657366	1.0	1.0	5	Q96BN8,Q8TCT8,O15111,P63244	4
G protein beta gamma signalling	0.5715950044681096	0.2743334251771909	0.7838283998683337	1.0	1.0	3	Q13153	1
N glycan trimming in the er and calnexin calreticulin cycle	0.3506665183424063	0.2737636949532103	0.784266225305537	1.0	1.0	13	P27824,Q9UBV2,P62191,Q9BUN8	4
Vitamin b5 pantothenate metabolism	0.5709958349110149	0.2729033413248586	0.7849275179774182	1.0	1.0	3	P49327,Q9NVE7	2
Interleukin 3 interleukin 5 and gm csf signaling	0.416397972210623	0.2565657295862565	0.79751403340186	1.0	1.0	6	P46108	1
Transcriptional regulation by mecp2	0.3760451085609938	0.2504641407999243	0.8022284325728146	1.0	1.0	8	Q9HCE1,Q14739	2
Cd28 co stimulation	0.3942040947024463	0.2453760842923056	0.8061652450341343	1.0	1.0	7	P62993,P31751,Q13153,Q13177	4
Maturation of sars cov 2 spike protein	0.3595833828350936	0.2406661036981667	0.8098139121947519	1.0	1.0	9	P46977	1
Carboxyterminal post translational modifications of tubulin	0.4087590245708594	0.2321127127352487	0.8164504711621479	1.0	1.0	6	Q9BVA1,Q13885,Q14166	3
Tp53 regulates transcription of genes involved in g1 cell cycle arrest	0.5760787282361782	0.2285603359996163	0.8192106557983905	1.0	1.0	2	P04637	1
Methionine salvage pathway	0.54823744020965	0.2214984277345252	0.8247043606856912	1.0	1.0	3	Q13126	1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.3544301262781164	0.2192681445825271	0.826441175041402	1.0	1.0	9	Q92600	1
Cytosolic iron sulfur cluster assembly	0.4042876231882437	0.2181720657577951	0.8272950491275299	1.0	1.0	6	P18074	1
Dap12 interactions	0.4033033076397656	0.2161032712453355	0.8289072498764514	1.0	1.0	5	P10321	1
Ns1 mediated effects on host pathways	0.2926710177763189	0.2125710894604565	0.831661523326517	1.0	1.0	31	Q7Z3B4,P57740,P52292,Q92621,Q8NFH4,Q9BTX1,Q99567,Q12769,Q86U42,Q9BW27	10
Cooperation of pdcl phlp1 and tric cct in g protein beta folding	0.3440941891378671	0.2073115386739026	0.8357665633351274	1.0	1.0	11	P17987,P78371,P50990,P49368,P50991,P68400,P67870,P48643,Q99832,P19784	10
Cargo concentration in the er	0.3329063884422483	0.2048603737569826	0.8376812157217668	1.0	1.0	14	Q96PC5,P49257,O75396,Q13190,Q9HCU5	5
Activation of the pre replicative complex	0.3207709151316681	0.1979514268343283	0.8430830673987042	1.0	1.0	17	Q9Y619,Q14566	2
Signaling by notch1	0.3948465327775722	0.1925851316764344	0.8472838901466544	1.0	1.0	5	P63208,Q13616,Q92542,Q13573	4
Signaling by notch1 pest domain mutants in cancer	0.3948465327775722	0.1925851316764344	0.8472838901466544	1.0	1.0	5	P63208,Q13616,Q92542,Q13573	4
Response to elevated platelet cytosolic ca2	0.2882804186904454	0.1855002031089644	0.8528367209724066	1.0	1.0	32	Q9Y6I9,Q9NTK5,Q9NZJ7,O43852,O94919,Q8NBX0	6
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol	0.5266944339265396	0.1782703219197211	0.8585106851338853	1.0	1.0	3	O14975,P51659	2
Beta oxidation of pristanoyl coa	0.5266944339265353	0.1782703219197129	0.8585106851338917	1.0	1.0	3	P51659,O15254	2
Muscle contraction	0.2887834510847701	0.1725687326122436	0.8629904308772707	1.0	1.0	24	Q12797,P05023,P08670,P16615	4
Pi metabolism	0.3286910184182777	0.1699487746098734	0.8650504224201752	1.0	1.0	13	Q8TBX8,Q10713,Q9NTJ5,Q01968	4
Flt3 signaling in disease	0.385158695083506	0.1669735587823203	0.8673908538640382	1.0	1.0	5	Q14789	1
Oncogene induced senescence	0.386346361899337	0.1651711700472027	0.8688092565377568	1.0	1.0	6	Q9HCE1	1
Microrna mirna biogenesis	0.3659361810875932	0.151466493889453	0.8796077398635849	1.0	1.0	7	P30876	1
Sars cov 2 infection	0.2965270929699923	0.1385811195668729	0.8897811637353747	1.0	1.0	21	Q10472,P46977	2
Notch1 intracellular domain regulates transcription	0.3946969696969744	0.1363281779259671	0.8915618490668871	1.0	1.0	4	Q13616,P63208,Q13573	3
Amino acid transport across the plasma membrane	0.5020825444907143	0.1355848361541798	0.8921494937393806	1.0	1.0	3	P08195,Q96QD8	2
Tp53 regulates metabolic genes	0.2823318294306911	0.1345074742473184	0.8930013012041176	1.0	1.0	30	Q9HCE1,P31751,P13073,O43819,P00403	5
Folding of actin by cct tric	0.3437025796661616	0.1322254537194407	0.8948059687222489	1.0	1.0	8	P17987,P78371,P50990,P49368,P50991,P48643,Q99832	7
Flt3 signaling	0.3708616810933584	0.1318801139281066	0.895079118015754	1.0	1.0	5	P31751	1
Miscellaneous transport and binding events	0.3911914395489649	0.1293124414420958	0.8971104272427084	1.0	1.0	4	Q8N4V1	1
Cyclin a b1 b2 associated events during g2 m transition	0.3215128662535187	0.1279382444949248	0.8981978449967212	1.0	1.0	12	P53350,P06493,P30154,Q99640	4
Inositol phosphate metabolism	0.3848484848484906	0.1170941616222305	0.9067854362606108	1.0	1.0	4	Q9NPH2,Q9UNW1,Q01968	3
Fcgr3a mediated il10 synthesis	0.3848484848484901	0.1170941616222296	0.9067854362606116	1.0	1.0	4	P10644,O43865,P13861	3
Pre notch processing in golgi	0.4868784530536599	0.1128126048455469	0.910179124919464	1.0	1.0	3	P16615	1
Metabolism of ingested semet sec mesec into h2se	0.5064345193035481	0.1119349124184169	0.9108750144354432	1.0	1.0	2	P23526	1
Bbsome mediated cargo targeting to cilium	0.3654283548142448	0.1097496015633729	0.912607961620126	1.0	1.0	6	P17987,P78371,P50990,P49368,P48643	5
Hiv transcription elongation	0.3017540614474089	0.1026548022063536	0.9182369466699144	1.0	1.0	17	Q8IXH7,P30876	2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux	0.4791015842793737	0.1022145736619348	0.9185863602339605	1.0	1.0	3	Q9HCE1	1
Irak1 recruits ikk complex	0.4977289931869695	0.1016060442480935	0.9190693816663214	1.0	1.0	2	O15111	1
Ticam1 rip1 mediated ikk complex recruitment	0.4977289931869695	0.1016060442480935	0.9190693816663214	1.0	1.0	2	O15111	1
Ikk complex recruitment mediated by rip1	0.4977289931869695	0.1016060442480935	0.9190693816663214	1.0	1.0	2	O15111	1
Fbxw7 mutants and notch1 in cancer	0.497350492051466	0.1011771974941529	0.9194097975806894	1.0	1.0	2	P63208	1
Intraflagellar transport	0.3207648634277852	0.1003863965226719	0.9200375692120688	1.0	1.0	10	A0AVF1,Q9BVA1,Q13885,Q92973	4
Beta oxidation of butanoyl coa to acetyl coa	0.4756117361261335	0.097686574593358	0.922181176487415	1.0	1.0	3	P40939	1
Regulation of mecp2 expression and activity	0.3590792616238749	0.0943686724461744	0.9248163004894628	1.0	1.0	6	Q14739	1
Rhobtb2 gtpase cycle	0.2915533327433102	0.092646611538338	0.9261843123116358	1.0	1.0	20	P07900,Q96DH6,P07910,P38159,O43396,P62995	6
Rap1 signalling	0.4886449659348875	0.0917688323920297	0.926881707687534	1.0	1.0	2	P31946	1
Notch4 activation and transmission of signal to the nucleus	0.4886449659348875	0.0917688323920297	0.926881707687534	1.0	1.0	2	Q92542	1
Transcriptional regulation of pluripotent stem cells	0.4871309613928744	0.0902203439036964	0.928112118154955	1.0	1.0	2	Q99626	1
Pka mediated phosphorylation of creb	0.4859954579863635	0.0890757585083523	0.9290217027050816	1.0	1.0	2	P10644	1
Pka activation in glucagon signalling	0.4859954579863635	0.0890757585083523	0.9290217027050816	1.0	1.0	2	P10644	1
Vasopressin regulates renal water homeostasis via aquaporins	0.4859954579863635	0.0890757585083523	0.9290217027050816	1.0	1.0	2	P10644	1
Creb1 phosphorylation through the activation of adenylate cyclase	0.4859954579863635	0.0890757585083523	0.9290217027050816	1.0	1.0	2	P10644	1
Glucagon signaling in metabolic regulation	0.4859954579863635	0.0890757585083523	0.9290217027050816	1.0	1.0	2	P10644	1
Uptake and function of diphtheria toxin	0.3680357041168813	0.0876832358113082	0.9301284441820106	1.0	1.0	4	P13639	1
Ret signaling	0.3643939393939416	0.0818801858417612	0.9347419909316516	1.0	1.0	4	P62993,Q9NR12,P19174	3
Gap junction assembly	0.347081842629201	0.0809606898700929	0.9354732147774982	1.0	1.0	5	Q9BVA1,Q13885	2
Transport of connexons to the plasma membrane	0.347081842629201	0.0809606898700929	0.9354732147774982	1.0	1.0	5	Q9BVA1,Q13885	2
Signaling by fgfr	0.2966911390488256	0.0790114387999511	0.9370235246629052	1.0	1.0	17	P52597,P31943,P30876,P62993,Q01085	5
Signaling by fgfr2	0.2966911390488253	0.0790114387999503	0.937023524662906	1.0	1.0	17	P52597,P31943,P30876,P62993,Q01085	5
Mitotic prophase	0.2756920968648554	0.0764423253110832	0.939067197364992	1.0	1.0	55	P50402,P57740,Q01105,Q7Z3B4,P62820,Q8NFH4,Q9BTX1,P61019,P42167,Q9BW27	10
Metabolism of nitric oxide nos3 activation and regulation	0.3445847846243655	0.0761657550171079	0.9392872270584096	1.0	1.0	5	P50570	1
Oncogenic mapk signaling	0.2726995969619964	0.0736483469261154	0.9412902002821883	1.0	1.0	24	Q99956,Q9NRY5	2
Uptake and actions of bacterial toxins	0.3493573553612898	0.0721640059047902	0.9424713895887802	1.0	1.0	6	P07900,P13639	2
Pten regulation	0.271909511237213	0.0716882078965732	0.942850040751869	1.0	1.0	62	P25787,Q9HCE1,P31751,O00231,P43686,Q92530,P49721,P62191,P25789,P61289,P28066,Q9UL46,P28074,P28072	14
Uptake and function of anthrax toxins	0.4663133989401863	0.0714386888245285	0.9430486190228264	1.0	1.0	2	Q8WUM4	1
Neurotransmitter receptors and postsynaptic signal transmission	0.272707305952744	0.0683198752113067	0.9455310029622416	1.0	1.0	28	Q15418,P51812	2
Activation of ampk downstream of nmdars	0.3474711128671348	0.0680469516803588	0.9457482588369164	1.0	1.0	6	P04350,Q9BVA1,Q13885,P68371	4
Cd28 dependent vav1 pathway	0.338295064172902	0.0645559868999933	0.9485275289355052	1.0	1.0	5	P62993,Q13153	2
Transcriptional regulation by small rnas	0.2694703583156662	0.0560288756818991	0.9553188038182	1.0	1.0	33	Q7Z3B4,P57740,P30876,Q8NFH4,Q9BTX1,O15397,Q12769,Q9BW27	8
Host interactions of hiv factors	0.2701202730673538	0.0556096375138107	0.9556527867616116	1.0	1.0	92	P57740,Q92530,P62191,P25789,P61289,Q9UL46,P25787,P49721,Q8NFH4,Q9BW27,Q7Z3B4,O00231,P43686,P12235,Q12769,P28074,Q9BTX1,P28066,P12236,P28072,P05141	21
Phase ii conjugation of compounds	0.2702441561322041	0.0549543641855291	0.9561748209200632	1.0	1.0	26	P21964,O60701,Q8TB61,P78417	4
Negative regulation of flt3	0.4394398183194503	0.053475565798512	0.9573529984549802	1.0	1.0	2	P22681	1
Alk mutants bind tkis	0.3401270739758211	0.0482600356956217	0.9615090043149396	1.0	1.0	4	Q9NR09	1
Irs mediated signalling	0.3389202784262531	0.0468116518503079	0.9626633423816806	1.0	1.0	4	P31751	1
Tnfr1 induced nfkappab signaling pathway	0.4237031427489561	0.0460124027135947	0.9633003644444964	1.0	1.0	3	O15111,P63244	2
Regulation by c flip	0.4235427706283025	0.0456982495463448	0.96355075901321	1.0	1.0	2	P49327	1
Caspase activation via death receptors in the presence of ligand	0.4235427706283025	0.0456982495463448	0.96355075901321	1.0	1.0	2	P49327	1
Caspase activation via extrinsic apoptotic signalling pathway	0.4235427706283025	0.0456982495463448	0.96355075901321	1.0	1.0	2	P49327	1
Synthesis of pips at the plasma membrane	0.3148710166919584	0.0439751404657519	0.9649242197272738	1.0	1.0	8	Q01968,P61106,O00443,Q13614,Q8TBX8,Q96T51,P20339	7
Pyruvate metabolism	0.2898677608303918	0.0413842685750644	0.9669895539117102	1.0	1.0	16	P21796,P07195	2
Perk regulates gene expression	0.3011773642233221	0.0402923325891846	0.9678600665242584	1.0	1.0	11	P05198,Q9NQT4,Q13868,O95453,Q92945,Q15024,Q9NQT5,Q5RKV6,P08243,P20042	10
Transport of mature mrnas derived from intronless transcripts	0.2670456598344362	0.0396216541189501	0.9683947635022384	1.0	1.0	33	Q7Z3B4,P57740,Q8NFH4,Q9BTX1,Q12769,Q9UBU9,Q9BW27	7
Post chaperonin tubulin folding pathway	0.3026887464697401	0.0386863885978611	0.9691404256115508	1.0	1.0	10	Q9BVA1,Q99426,Q13885	3
Mastl facilitates mitotic progression	0.3224706328154682	0.0382966189660193	0.9694511864847984	1.0	1.0	5	P06493,P30154,P14635,P30153	4
Wnt mediated activation of dvl	0.4123438091631978	0.0382631073206849	0.9694779053258442	1.0	1.0	3	P68400,P19784	2
Copi independent golgi to er retrograde traffic	0.2662713215596746	0.0340490070642079	0.9728380713494036	1.0	1.0	25	Q9UJW0,O75935,P61163,Q10472,Q13561,Q13885	6
Signaling by fgfr4 in disease	0.3845571536714526	0.0335130530566036	0.9732654568454888	1.0	1.0	2	P62993	1
Dna replication	0.2618196891902693	0.0329871032656986	0.9736848721484804	1.0	1.0	83	Q9UJX3,Q92530,P62191,P25789,P61289,Q9UL46,Q9UJX2,Q14566,P25787,P49721,P25205,Q06323,Q9UJX4,O00231,P43686,P28074,Q9Y619,P28066,P28072	19
Glucagon like peptide 1 glp1 regulates insulin secretion	0.4024990533888715	0.0324399680038061	0.9741211893907092	1.0	1.0	3	P10644,P13861	2
Frs mediated fgfr4 signaling	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Frs mediated fgfr3 signaling	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Activated ntrk2 signals through frs2 and frs3	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr2	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Met activates ptpn11	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Signal regulatory protein family interactions	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Signaling by flt3 itd and tkd mutants	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr3	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr1	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Stat5 activation	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Pi 3k cascade fgfr4	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Frs mediated fgfr2 signaling	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Frs mediated fgfr1 signaling	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Tie2 signaling	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Stat5 activation downstream of flt3 itd mutants	0.3641180923542697	0.0299948104697622	0.9760711919552798	1.0	1.0	2	P62993	1
Ksrp khsrp binds and destabilizes mrna	0.300948766603427	0.0289349973520326	0.9769164334489469	1.0	1.0	9	Q9NQT4,P63104,Q13868,O95453,Q92945,Q15024,Q9NQT5,Q5RKV6	8
Atf4 activates genes in response to endoplasmic reticulum stress	0.3009487666034259	0.0289349973520293	0.9769164334489496	1.0	1.0	9	Q9NQT4,O95453,Q13868,Q92945,Q15024,Q9NQT5,Q5RKV6,P08243	8
Hiv elongation arrest and recovery	0.289448975734595	0.0279619014133483	0.9776925375243908	1.0	1.0	15	Q8IXH7	1
Activation of atr in response to replication stress	0.2890288224027323	0.0263262026318968	0.9789971554733436	1.0	1.0	15	Q9Y619,Q14566	2
Signaling by ntrk3 trkc	0.3847027641045097	0.0238132433150299	0.9810015764077054	1.0	1.0	3	Q8WX92,P62993	2
Signaling by erythropoietin	0.3847027641045084	0.0238132433150293	0.9810015764077058	1.0	1.0	3	P62993,P46109	2
Fceri mediated ca 2 mobilization	0.3847027641045049	0.0238132433150279	0.9810015764077068	1.0	1.0	3	P62993,O43865	2
Cd209 dc sign signaling	0.382072292130036	0.0227277774538076	0.9818674183515016	1.0	1.0	3	Q13153	1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.264986210242811	0.0212420726046129	0.9830525527593884	1.0	1.0	28	Q9UJW0,O60884,O75935,P61163,P07900,Q15185,Q13561,Q13885	8
Mapk3 erk1 activation	0.3642559636501358	0.016507031148497	0.986829892807666	1.0	1.0	3	P06493,Q02750	2
Downstream signaling of activated fgfr1	0.3642559636501362	0.016507031148497	0.986829892807666	1.0	1.0	3	P62993,P19174	2
Downstream signaling of activated fgfr4	0.3642559636501362	0.016507031148497	0.986829892807666	1.0	1.0	3	P62993,P19174	2
Downstream signaling of activated fgfr2	0.3642559636501362	0.016507031148497	0.986829892807666	1.0	1.0	3	P62993,P19174	2
Downstream signaling of activated fgfr3	0.3642559636501362	0.016507031148497	0.986829892807666	1.0	1.0	3	P62993,P19174	2
Gab1 signalosome	0.3642559636501356	0.0165070311484967	0.9868298928076662	1.0	1.0	3	P62993,P41240	2
Prolactin receptor signaling	0.3642559636501337	0.0165070311484962	0.9868298928076666	1.0	1.0	3	Q13616,P63208	2
Signaling by cytosolic fgfr1 fusion mutants	0.3044203148664017	0.0133866298440322	0.9893193337264244	1.0	1.0	5	O95684	1
Activation of rac1	0.3038406953239678	0.0132228034004145	0.9894500367475508	1.0	1.0	4	Q13153	1
Tristetraprolin ttp zfp36 binds and destabilizes mrna	0.3008345978755696	0.0076200164751237	0.9939201653387386	1.0	1.0	8	Q9NQT4,Q13868,Q92973,Q15024,Q9NQT5,Q5RKV6,P31946	7
Interferon alpha beta signaling	0.2934366839897451	0.0075175659869958	0.994001906660052	1.0	1.0	9	P10321	1
Nuclear import of rev protein	0.2622956690728972	0.0045788695675643	0.9963466034323284	1.0	1.0	29	Q7Z3B4,P57740,Q92621,Q8NFH4,Q9BTX1,Q99567,Q12769,Q9BW27	8
Sumoylation of chromatin organization proteins	0.2622081757806076	0.0043407746556036	0.996536573796873	1.0	1.0	31	Q7Z3B4,P57740,Q92621,Q8NFH4,Q8N1F7,Q9BTX1,Q99567,Q12769,Q9NRG9,Q15022,Q9BW27	11
Leishmania infection	0.2619762032069807	0.0041526280405908	0.9966866917222827	1.0	1.0	32	Q9UQB8,P46108,P09601	3
Enos activation	0.2544490723210955	0.003948114418374	0.9968498686451336	1.0	1.0	3	P07900,O75608	2