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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b1b139b3187293b40ee1039f8abdb54b063554aeb8089f103ced3a41648da5a9
+size 62121

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2644,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.452830188679245
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C198/C198_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9598636879969712	2.181621095850137	0.02913750862557	0.7913783841325687	0.2784559650834257	3	Q9H3G5,Q9HB40	2
+Cysteine peptidase, histidine active site [IPR025660]	0.8807721423164265	1.0687087628960836	0.2852009217210449	0.9999999813038948	0.5212292707315649	2	P53634	1
+Cysteine peptidase, asparagine active site [IPR025661]	0.8807721423164265	1.0687087628960836	0.2852009217210449	0.9999999813038948	0.5212292707315649	2	P53634	1
+Histidine acid phosphatase active site [IPR033379]	0.8493565480696422	0.9537763176488712	0.3401968795322587	0.9999999997314896	0.5561766756728779	2	Q9NPH0	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME6", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1"], "leading_proteins": ["ACP6", "CPVL", "CTSC", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c99fe0524ae9c097f1cf94c0db8b7cc12c304b6b5c89170ee15355491069d56a
+size 59703

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	5	6	2.8312668735707787	0.0046364018299505	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	9.5501646683206e-09	8.471957845697295e-13	6.275167299951582e-11	1.5040937032126972e-08	9.4206715064497e-07

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2644,
+    "annotations_size": 27,
+    "title": "Average number of proteins per term",
+    "value": 4.555555555555555
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C198/C198_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9878695981804388	2.8312668735707787	0.0046364018299505	0.1179212564168751	0.1251828494086637	6	Q9BVA1,P07437,Q13885,P68371,P04350	5
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6585919757759219	0.3457506291806103	0.729530131497762	0.9999999999999996	0.8564049369756337	2	P34897	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHUK", "COX2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["SHMT2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "Mini-chromosome maintenance, conserved site [IPR018525]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a2e9fb3e29f0d58c6436c3c6088d753d3eda3c29d0813a3fb8c53242a973dd7f
+size 60765

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	5	6	2.8312668735707787	0.0046364018299505	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.7805540506852606e-06	1.8108482464958843e-10	1.2912404950479516e-08	2.765770662469611e-06	0.0001429815632908

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2644,
+    "annotations_size": 265,
+    "title": "Average number of proteins per term",
+    "value": 2.4754716981132074
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C198/C198_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,27 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9878695981804388	2.8312668735707787	0.0046364018299505	0.7081465740957209	0.6778898013059257	6	Q9BVA1,P07437,Q13885,P68371,P04350	5
+Tetraspanin, conserved site [IPR018503]	0.9844814534443602	1.4572235762204664	0.1450546746828931	1.0	0.6778898013059257	2	O43657	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.6898165534998274	1.33828823192908	0.1808024965078627	1.0	0.6778898013059257	4	Q9P2W9	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6429131834369312	1.3241239427969835	0.1854618850498086	1.0	0.6778898013059257	8	P28072,P49721,Q99436	3
+Haem oxygenase conserved site [IPR018207]	0.9292202876608614	1.2491049007721169	0.2116267083925227	1.0	0.7010134715502315	2	P30519	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8966691900075685	1.127563655195038	0.2595042432168946	1.0	0.7759692512556903	2	P40939	1
+ABC transporter-like, conserved site [IPR017871]	0.5972794556132747	1.1243947481668586	0.2608455990530998	1.0	0.7759692512556903	7	O75027	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5928901714430574	1.118070869154186	0.2635367268415551	1.0	0.7759692512556903	6	P51648	1
+Intermediate filament protein, conserved site [IPR018039]	0.5529813307579957	0.9035130467324692	0.366253667083442	1.0	0.8723084974021048	8	Q16352,P07196,P08670	3
+Chromo domain, conserved site [IPR023779]	0.553409090909099	0.7667512256233738	0.4432294406038291	1.0	0.9157533925338563	4	P83916,P45973,Q14781	3
+Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]	0.5292608328998366	0.6708798113961122	0.502297098402126	1.0	0.9284907700239912	4	P40939	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.9284907700239912	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.9284907700239912	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.9284907700239912	2	P05067	1
+Thioredoxin, conserved site [IPR017937]	0.4876612214211027	0.5757304958129952	0.5647973592194044	1.0	0.9714517760001684	10	O95881,O43396,Q9H1E5,P07237	4
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.7316426949280814	0.5527019830465326	0.5804674952369027	1.0	0.974772760970022	2	P82675	1
+Kinesin motor domain, conserved site [IPR019821]	0.4547902975476939	0.4186015573638327	0.6755073512273495	1.0	0.985188936909938	11	Q86Y91,Q14807	2
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.407395715096293	0.2424949285472301	0.8083966860459872	1.0	0.985188936909938	10	Q06136,Q53GQ0	2
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.4051495645588769	0.1456432558777058	0.8842030187923291	1.0	0.985188936909938	3	P42345,O00443	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.5393641180923456	0.1205029148092209	0.9040847707884324	1.0	0.985188936909938	2	Q9H3P7	1
+DNA-directed DNA polymerase, family B, conserved site [IPR017964]	0.518168054504154	0.0966985061748505	0.9229658261723586	1.0	0.985188936909938	2	P09884	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.4731264193792492	0.0605348128969317	0.9517296899960156	1.0	0.985188936909938	2	P50570	1
+Ribosomal S11, conserved site [IPR018102]	0.4485238455715291	0.0478034128532048	0.9618729166043556	1.0	0.9907740059908156	2	P82912	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.324109173616369	0.0350241580021306	0.9720604773882138	1.0	0.9907740059908156	6	P25205,P33991,P49736,Q14566,P33993	5
+Profilin conserved site [IPR027310]	0.3050719152157385	0.0257493940298873	0.9794572261622544	1.0	0.9907740059908156	2	P35080	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.9907740059908156	2	P30876	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ARIH2", "ARSA", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP6", "MPST", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF8", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIF", "PPIG", "PPIH", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB7", "ACBD3", "ALDH3A2", "APP", "CBX1", "CBX2", "CBX5", "DNM2", "HADHA", "HMOX2", "HSD17B12", "INA", "KDSR", "KIF18B", "KIF22", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "MRPS11", "MRPS5", "MTOR", "NEFL", "P4HB", "PFN2", "PIK3C2A", "POLA1", "POLR2B", "PSMB2", "PSMB6", "PSMB7", "STX18", "TMX4", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TXNDC12", "TXNL1", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "RNA recognition motif domain [IPR000504]", "3": "MCM, AAA-lid domain [IPR041562]", "4": "MCM domain [IPR001208]", "5": "MCM N-terminal domain [IPR027925]", "6": "MCM OB domain [IPR033762]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:8f3f28d153e42c547bfa0bbaa179d8cc41101a23e7e2a87c81dca2269e5a6e06
+size 90598

interpro_domain/df_merge.tsv

@@ -0,0 +1,5 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin/FtsZ, GTPase domain [IPR003008]	5	6	2.8312668735707787	0.0046364018299505	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.7805540506852606e-06	1.8108482464958843e-10	1.2912404950479516e-08	2.765770662469611e-06	0.0001429815632908
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	5	6	2.8312668735707787	0.0046364018299505	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.2096464196687304e-06	1.2117172578108348e-10	8.676815030932978e-09	1.8818469985730976e-06	9.937036022358197e-05
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	5	2.331166149936524	0.0197446003021508	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0001064841286758	0.0015075035399645	0.0058956460302812	0.000142755965642	0.0019884945269669
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	2.138175756367449	0.0325024812507388	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.3936330765223108	1.0	1.0	0.4172977923286156	0.0034992238505004

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2644,
+    "annotations_size": 2312,
+    "title": "Average number of proteins per term",
+    "value": 2.0666089965397925
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C198/C198_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,200 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.9878695981804388	2.8312668735707787	0.0046364018299505	0.9999784317393886	0.8047152360846115	6	Q9BVA1,P07437,Q13885,P68371,P04350	5
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.9878695981804388	2.8312668735707787	0.0046364018299505	0.9999784317393886	0.8047152360846115	6	Q9BVA1,P07437,Q13885,P68371,P04350	5
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8976098721747645	2.331166149936524	0.0197446003021508	1.0	0.8047152360846115	5	O43169,O00264,O15173	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8507010231148188	2.138175756367449	0.0325024812507388	1.0	0.8047152360846115	5	Q9HD20,P16615,P35670,P05023	4
+ABC transporter type 1, transmembrane domain [IPR011527]	0.8941637378619121	1.9190553800675252	0.0549773255506031	1.0	0.8047152360846115	3	O75027	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8936009087466921	1.916781615529747	0.0552656815038599	1.0	0.8047152360846115	3	Q96G23,Q15629	2
+FAD dependent oxidoreductase [IPR006076]	0.8878908396833805	1.8936916759890112	0.0582659468510002	1.0	0.8047152360846115	3	Q96CU9	1
+Zinc finger, CHHC-type [IPR012996]	0.8799697084437716	1.861595887180489	0.0626600734596789	1.0	0.8047152360846115	3	P31943,P52597	2
+GOLD domain [IPR009038]	0.7501073857993159	1.836129795899257	0.0663384625186453	1.0	0.8047152360846115	6	Q9Y3A6,P49755,Q15363,Q9Y3B3	4
+SET domain [IPR001214]	0.853697216055886	1.7546318282241915	0.0793223036064301	1.0	0.8047152360846115	3	Q03164	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8500567966679318	1.7397525317112656	0.0819024808006405	1.0	0.8047152360846115	3	P16615,P05023	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8500567966679318	1.7397525317112656	0.0819024808006405	1.0	0.8047152360846115	3	P16615,P05023	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6686878094285698	1.4687068037545394	0.1419123312611527	1.0	0.8047152360846115	6	Q9H4M9,Q9H223,O60313,O95140	4
+Dynamin, N-terminal [IPR045063]	0.6686878094285698	1.4687068037545394	0.1419123312611527	1.0	0.8047152360846115	6	Q9H4M9,Q9H223,O60313,O95140	4
+CBS domain [IPR000644]	0.6675247904114112	1.463376004569021	0.1433645208471412	1.0	0.8047152360846115	6	P51790	1
+ERAP1-like C-terminal domain [IPR024571]	0.7819007951533556	1.4591750952836977	0.144516921584572	1.0	0.8047152360846115	3	P55786,Q9NZ08	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6789391810905095	1.3988212496298646	0.1618665924119229	1.0	0.8047152360846115	5	P55786,Q9NZ08	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6789391810905095	1.3988212496298646	0.1618665924119229	1.0	0.8047152360846115	5	P55786,Q9NZ08	2
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9666919000756996	1.3900925053223518	0.1645007888469867	1.0	0.8047152360846115	2	Q8IV08	1
+Major facilitator superfamily domain [IPR020846]	0.7633283911168092	1.3822974362980844	0.1668803928518949	1.0	0.8047152360846115	3	P53985	1
+START domain [IPR002913]	0.7625899280575639	1.3792394852503322	0.1678209276125868	1.0	0.8047152360846115	3	Q9Y5P4,Q9NQZ5	2
+Beta-Casp domain [IPR022712]	0.7403887138556309	1.2873167316417	0.197983914075118	1.0	0.8207292038788845	3	Q9NV88	1
+Longin domain [IPR010908]	0.739113971980316	1.2820414777936888	0.1998280964121535	1.0	0.8220686101510656	3	P51809,O75396	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.739113971980316	1.2820414777936888	0.1998280964121535	1.0	0.8220686101510656	3	P51809,O75396	2
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7286306791069426	1.2386825605459273	0.215463079588182	1.0	0.8439174614434278	3	Q9NZW5	1
+Guanylate kinase-like domain [IPR008144]	0.7286306791069426	1.2386825605459273	0.215463079588182	1.0	0.8439174614434278	3	Q9NZW5	1
+Post-SET domain [IPR003616]	0.922028766086298	1.2221566601756753	0.2216483897761723	1.0	0.8504039129828902	2	Q03164	1
+Cyclic nucleotide-binding domain [IPR000595]	0.6587834001190334	1.206351609279661	0.2276819460424008	1.0	0.8504039129828902	4	Q6P4Q7,P10644	2
+Reticulon [IPR003388]	0.9174867524602554	1.2051616315214435	0.2281409110888668	1.0	0.8504039129828902	2	O95197	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9171082513247524	1.2037463120214138	0.2286876462830891	1.0	0.8504039129828902	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.9171082513247524	1.2037463120214138	0.2286876462830891	1.0	0.8504039129828902	2	Q15392	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6055940685251364	1.1771549094124445	0.239133682138299	1.0	0.8628712441006924	6	Q92604,Q9HCL2	2
+Intermediate filament head, DNA-binding domain [IPR006821]	0.6489995168833398	1.1648102086856649	0.2440958256527008	1.0	0.8660582571562742	4	P07196,P08670	2
+BTB/POZ domain [IPR000210]	0.7092010602044698	1.1584965878568	0.2466614433178711	1.0	0.8661429442756001	3	Q9NXV2,Q08380	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7073078379401788	1.1507001065917657	0.2498556326686982	1.0	0.8673749762100784	3	P10321,P04439	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7073078379401788	1.1507001065917657	0.2498556326686982	1.0	0.8673749762100784	3	P10321,P04439	2
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.6412878787878851	1.1321106655907125	0.2575879114085504	1.0	0.8673749762100784	4	Q9NRG0,Q01658,Q9NR33	3
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8966691900075685	1.127563655195038	0.2595042432168946	1.0	0.8673749762100784	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8966691900075685	1.127563655195038	0.2595042432168946	1.0	0.8673749762100784	2	P40939	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5972794556132747	1.1243947481668586	0.2608455990530998	1.0	0.8673749762100784	7	O75027	1
+Marvel domain [IPR008253]	0.8830431491294456	1.0770917875139308	0.2814392616363315	1.0	0.8689838449651057	2	O43760	1
+Peptidase C1A, papain C-terminal [IPR000668]	0.8807721423164265	1.0687087628960836	0.2852009217210449	1.0	0.8703395198377454	2	P53634	1
+Peptidase M16, C-terminal [IPR007863]	0.5806938777966174	1.0469558802941656	0.2951199272317997	1.0	0.872997867390542	7	Q10713	1
+Peptidase M16, N-terminal [IPR011765]	0.5806938777966174	1.0469558802941656	0.2951199272317997	1.0	0.872997867390542	7	Q10713	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6811813706929208	1.0435569124099098	0.2966904366657286	1.0	0.872997867390542	3	Q9ULX6,Q5BKZ1	2
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.6754020207424749	1.019997519274433	0.3077296372655504	1.0	0.8740429009311458	3	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.6754020207424749	1.019997519274433	0.3077296372655504	1.0	0.8740429009311458	3	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.6754020207424749	1.019997519274433	0.3077296372655504	1.0	0.8740429009311458	3	P16435	1
+NOPS [IPR012975]	0.6702006815600239	0.9988486244430984	0.3178680269905207	1.0	0.8897226130775836	3	Q15233,Q8WXF1	2
+JmjC domain [IPR003347]	0.6054511724738199	0.9810355940538246	0.3265751891754798	1.0	0.8973865581957499	4	Q9NWT6	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.8538985616956833	0.9702599903366848	0.3319169149057257	1.0	0.8985853715012153	2	Q9HCL2	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.8538985616956833	0.9702599903366848	0.3319169149057257	1.0	0.8985853715012153	2	Q9HCL2	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8504920514761545	0.9578925367268596	0.3381169502322101	1.0	0.9014927799632384	2	O15254	1
+Tim44-like domain [IPR007379]	0.8417865253595753	0.9264183924267598	0.3542285894355892	1.0	0.9014927799632384	2	O43615	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8402725208175621	0.9209648650069988	0.3570687710113598	1.0	0.9014927799632384	2	O60506	1
+Band 7 domain [IPR001107]	0.5560803083433555	0.9179657406187858	0.3586368020916599	1.0	0.9014927799632384	8	Q9UJZ1,Q14254,O75477,P27105	4
+Intermediate filament, rod domain [IPR039008]	0.5529813307579957	0.9035130467324692	0.366253667083442	1.0	0.9014927799632384	8	Q16352,P07196,P08670	3
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8342165026495076	0.8992141009811045	0.3685386308687484	1.0	0.9014927799632384	2	Q9NVI7	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.8315669947009832	0.8897311101198655	0.373610285062897	1.0	0.9014927799632384	2	Q9NUQ9	1
+CARG-binding factor, N-terminal [IPR012956]	0.8277819833459494	0.876220235449815	0.3809103178844966	1.0	0.9081079916367087	2	Q99729	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8243754731264188	0.8640980854847736	0.3875340106440199	1.0	0.912355406882491	2	P98179	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.536422118869543	0.8125037233027192	0.4165026509922898	1.0	0.933095086331564	9	Q9Y680	1
+Zinc finger, CCHC-type [IPR001878]	0.5220271395438512	0.7747411359068065	0.4384926384303953	1.0	0.9540752232434244	7	Q9NUD5	1
+Metallo-beta-lactamase [IPR001279]	0.5516049009877348	0.7594918248221101	0.4475584026034891	1.0	0.96345905662874	4	Q9NV88	1
+LEM domain [IPR003887]	0.5121669620282076	0.7448365587863042	0.4563705310289556	1.0	0.9686734303050736	6	P50402,Q86XL3	2
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.5474101259592792	0.7426695602986034	0.4576817631922569	1.0	0.9690112055865366	4	Q9HCE1	1
+Zinc finger, RanBP2-type [IPR001876]	0.5153951354060851	0.7296629978405723	0.4655962041327721	1.0	0.9731609378011988	8	Q01844,P35637	2
+FAD/NAD(P)-binding domain [IPR023753]	0.535891335402572	0.6969080051441402	0.4858603676819593	1.0	0.9863551337066732	4	P00390	1
+G-patch domain [IPR000467]	0.5141462174652753	0.6695541543530433	0.5031420477667412	1.0	0.986934788909128	12	Q8IWZ8	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.7668433005298967	0.6659533487800751	0.5054409193862486	1.0	0.986934788909128	2	P05067	1
+Peptidase M41 [IPR000642]	0.7581377744133209	0.6372846668829686	0.5239394366489387	1.0	0.989225794594602	2	Q96TA2	1
+EH domain-containing protein, N-terminal [IPR031692]	0.7547312641937898	0.6261782504952337	0.5311980312948126	1.0	0.989225794594602	2	Q9H4M9	1
+Domain of unknown function DUF5600 [IPR040990]	0.7547312641937898	0.6261782504952337	0.5311980312948126	1.0	0.989225794594602	2	Q9H4M9	1
+Dynamin, GTPase domain [IPR001401]	0.5679359166406026	0.6014395427097607	0.5475472679378623	1.0	0.998052138556834	3	O60313	1
+Major sperm protein (MSP) domain [IPR000535]	0.5660734570238475	0.5946901665391201	0.5520505961426057	1.0	0.998052138556834	3	Q8NHP6,Q9P0L0	2
+Fxr1, tudor domain [IPR041560]	0.5645588792124138	0.5892192141658588	0.5557142294767601	1.0	0.998052138556834	3	Q06787,P51116	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.5645588792124138	0.5892192141658588	0.5557142294767601	1.0	0.998052138556834	3	Q06787,P51116	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.5645588792124138	0.5892192141658588	0.5557142294767601	1.0	0.998052138556834	3	Q06787,P51116	2
+Agenet-like domain [IPR008395]	0.5645588792124138	0.5892192141658588	0.5557142294767601	1.0	0.998052138556834	3	Q06787,P51116	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.7342922028766052	0.5609655131459327	0.5748210474234763	1.0	0.998052138556834	2	Q92945	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.7316426949280814	0.5527019830465326	0.5804674952369027	1.0	0.998052138556834	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.7316426949280814	0.5527019830465326	0.5804674952369027	1.0	0.998052138556834	2	P82675	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.7312641937925768	0.5515252233697475	0.5812736806808512	1.0	0.998052138556834	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.7312641937925768	0.5515252233697475	0.5812736806808512	1.0	0.998052138556834	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.7312641937925768	0.5515252233697475	0.5812736806808512	1.0	0.998052138556834	2	A1L0T0	1
+Chromo shadow domain [IPR008251]	0.5531995456266482	0.5487161323089763	0.5832002733823916	1.0	0.998052138556834	3	P83916,P45973	2
+Chromo domain subgroup [IPR017984]	0.5531995456266482	0.5487161323089763	0.5832002733823916	1.0	0.998052138556834	3	P83916,P45973	2
+Lamin tail domain [IPR001322]	0.5490344566452038	0.5341103747787243	0.5932651722491031	1.0	0.998052138556834	3	P20700,Q03252	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7252081756245232	0.5328268563769756	0.5941534411857421	1.0	0.998052138556834	2	P13674	1
+Acyl transferase [IPR014043]	0.7240726722180132	0.529348543636517	0.5965636865287456	1.0	0.998052138556834	2	P49327	1
+GNAT domain [IPR000182]	0.4903026652524147	0.5236431035810843	0.6005267956793172	1.0	0.998052138556834	4	Q9H9T3	1
+NLE [IPR012972]	0.7134746404239174	0.4973206216873103	0.6189629719097134	1.0	0.998052138556834	2	Q9GZL7	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.7089326267978764	0.4838435616137804	0.628496896934114	1.0	0.998052138556834	2	Q9NXV2	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.5324495110279128	0.4773752018195714	0.633094969392072	1.0	0.998052138556834	3	P61289	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.5324495110279128	0.4773752018195714	0.633094969392072	1.0	0.998052138556834	3	P61289	1
+Chitinase II [IPR011583]	0.7002271006812979	0.4584498905911636	0.6466292552665196	1.0	0.998052138556834	2	Q01459	1
+Glycoside hydrolase family 18, catalytic domain [IPR001223]	0.7002271006812979	0.4584498905911636	0.6466292552665196	1.0	0.998052138556834	2	Q01459	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.5191215448693584	0.4335785566447307	0.6645945090994112	1.0	0.998052138556834	3	Q9BYT8,Q99797	2
+Ubiquitin system component CUE [IPR003892]	0.4640222337310159	0.4312517906010056	0.6662852999225417	1.0	0.998052138556834	4	Q9Y679	1
+Immunoglobulin-like domain [IPR007110]	0.4471305566524076	0.4284482724173097	0.6683247862547517	1.0	0.998052138556834	8	P35613,Q13308,P10321,P04439	4
+Class II aldolase/adducin N-terminal [IPR001303]	0.6858440575321678	0.4178191024405558	0.6760793832657539	1.0	0.998052138556834	2	P35611	1
+SCP2 sterol-binding domain [IPR003033]	0.5054903445664441	0.3906175950239973	0.6960799179956827	1.0	0.998052138556834	3	P22307,Q6YN16	2
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.4268176692768295	0.3749712902680634	0.7076818184896163	1.0	0.998052138556834	6	Q8N4Q0,Q8N8N7	2
+Glycoside hydrolase family 2, catalytic domain [IPR006103]	0.6680545041635073	0.370008883476151	0.7113758713615645	1.0	0.998052138556834	2	P08236	1
+PB1 domain [IPR000270]	0.6612414837244458	0.3524580004594146	0.7244948108774252	1.0	0.998052138556834	2	Q92734	1
+Rho GTPase-activating protein domain [IPR000198]	0.4914804998106805	0.3485671663032226	0.7274142809832491	1.0	0.998052138556834	3	Q9H0H5,Q68EM7	2
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6585919757759219	0.3457506291806103	0.729530131497762	1.0	0.998052138556834	2	P34897	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.6566994700984048	0.3410006993675414	0.7331030552415119	1.0	0.998052138556834	2	P00387	1
+OCRE domain [IPR041591]	0.6506434519303501	0.3260338592059913	0.744398737620007	1.0	0.998052138556834	2	P98175	1
+XPC-binding domain [IPR015360]	0.6502649507948468	0.3251103362055138	0.7450975663741366	1.0	0.998052138556834	2	P54725	1
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.6502649507948468	0.3251103362055138	0.7450975663741366	1.0	0.998052138556834	2	P54725	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4299242424242525	0.3222723603814608	0.7472463702757322	1.0	0.998052138556834	4	P51665,Q7L5N1,O00303	3
+Domain of unknown function DUF4217 [IPR025313]	0.6404239212717577	0.301599582824532	0.7629573260503268	1.0	0.998052138556834	2	Q13206	1
+APC10/DOC domain [IPR004939]	0.6377744133232339	0.2954368775629968	0.7676601656010482	1.0	0.998052138556834	2	Q9UM13	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.6347464042392067	0.2884819827378015	0.7729778202588979	1.0	0.998052138556834	2	Q9NRG7	1
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.4680045437334217	0.2833553257778151	0.7769044704172123	1.0	0.998052138556834	3	P28340,P09884	2
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.4680045437334217	0.2833553257778151	0.7769044704172123	1.0	0.998052138556834	3	P28340,P09884	2
+Legume-like lectin [IPR005052]	0.6290688872066554	0.2756978568992377	0.7827801418090607	1.0	0.998052138556834	2	Q12907	1
+HDGF-related, PWWP domain [IPR035496]	0.4611889435819609	0.2657431598949369	0.7904370213081886	1.0	0.998052138556834	3	Q7Z4V5,P51858	2
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.4589170768648141	0.2600103617695588	0.7948557808828571	1.0	0.998052138556834	3	Q96EY1,O60884	2
+Zinc finger, ZZ-type [IPR000433]	0.6218773656320903	0.2599912750191975	0.7948705037640966	1.0	0.998052138556834	2	Q13501	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.6192278576835665	0.25434346460442	0.7992302236588376	1.0	0.998052138556834	2	P55011	1
+SLC12A transporter, C-terminal [IPR018491]	0.6192278576835665	0.25434346460442	0.7992302236588376	1.0	0.998052138556834	2	P55011	1
+Brix domain [IPR007109]	0.4041666666666736	0.2497841621520615	0.8027542683646598	1.0	0.998052138556834	4	Q9NQ55,Q9H7B2,Q96G21	3
+RNA recognition motif domain [IPR000504]	0.2624776594242915	0.2444971540761666	0.8068458058230381	1.0	0.998052138556834	100	Q8IXT5,Q01085,Q07955,Q13151,Q9UHX1,P43243,P07910,Q96PK6,P52597,Q9BWF3,P98179,Q01844,O43390,Q13595,Q8IY67,P31942,P62995,P55795,Q92804,Q14103,Q9GZT3,Q14011,O60506,Q15233,P51991,P38159,P22626,O14979,P35637,P31943,Q99729,Q8WXF1	32
+Tudor domain [IPR002999]	0.3813914059895795	0.2046213001934429	0.8378680123623719	1.0	0.998052138556834	6	Q14739,Q16637	2
+YTH domain [IPR007275]	0.3836170535383071	0.1988766712316062	0.842359218648828	1.0	0.998052138556834	4	Q9H6S0	1
+Kinesin motor domain [IPR001752]	0.3958925074788286	0.1748964879959942	0.8611609699154161	1.0	0.998052138556834	12	Q86Y91,Q14807	2
+SKP1 component, POZ domain [IPR016073]	0.57532172596517	0.1719712786593248	0.8634601088850511	1.0	0.998052138556834	2	Q15369	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.5643451930355722	0.1547403082007564	0.877026051351993	1.0	0.998052138556834	2	P51116	1
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.4051495645588769	0.1456432558777058	0.8842030187923291	1.0	0.998052138556834	3	P42345,O00443	2
+CTP synthase GATase domain [IPR033828]	0.5556396669189939	0.1420299883417553	0.8870563185243696	1.0	0.998052138556834	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.5556396669189939	0.1420299883417553	0.8870563185243696	1.0	0.998052138556834	2	Q9NRF8	1
+Immunoglobulin C1-set [IPR003597]	0.3540855681534577	0.1373525908877506	0.8907521027850167	1.0	0.998052138556834	4	P10321,P04439	2
+MHC class I-like antigen recognition-like [IPR011161]	0.3540855681534577	0.1373525908877506	0.8907521027850167	1.0	0.998052138556834	4	P10321,P04439	2
+GUCT [IPR012562]	0.5514761544284577	0.1362476043125672	0.891625543213675	1.0	0.998052138556834	2	Q9NR30	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.5393641180923456	0.1205029148092209	0.9040847707884324	1.0	0.998052138556834	2	Q9H3P7	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.3367424242424333	0.1078010981387636	0.9141534717793988	1.0	0.998052138556834	4	Q9UKA9,P14866,Q8WVV9	3
+Ribosomal protein S10 domain [IPR027486]	0.5083270249810683	0.0871986957977275	0.9305135760121748	1.0	0.998052138556834	2	Q96GC5	1
+Peptidase M20, dimerisation domain [IPR011650]	0.5030280090840173	0.082472342128872	0.934271111177584	1.0	0.998052138556834	2	Q8IYS1	1
+DZF domain [IPR006561]	0.3178030303030367	0.0810155654703719	0.9354295737406776	1.0	0.998052138556834	4	Q96SI9,Q12906,Q96KR1	3
+Heat shock chaperonin-binding [IPR006636]	0.3563044301400977	0.0780510136089797	0.9377874737340072	1.0	0.998052138556834	3	P54725,P54727	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.3136363636363684	0.0758674915475147	0.939524520280926	1.0	0.998052138556834	4	O00469,P13674,Q32P28	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.3136363636363684	0.0758674915475147	0.939524520280926	1.0	0.998052138556834	4	O00469,P13674,Q32P28	3
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4943224829674431	0.0752770794490132	0.9399942576798496	1.0	0.998052138556834	2	Q9Y305	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.4935654806964352	0.0746840278734945	0.940466116089099	1.0	0.998052138556834	2	Q15418	1
+PABP, RNA recognition motif 2 [IPR045305]	0.4928084784254261	0.074096100312734	0.9409339182327452	1.0	0.998052138556834	2	Q13310	1
+IPT domain [IPR002909]	0.4822104466313297	0.0663907277955119	0.9470667520645196	1.0	0.998052138556834	2	Q04206	1
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.4822104466313295	0.0663907277955116	0.9470667520645196	1.0	0.998052138556834	2	Q9UID3	1
+GINS subunit, domain A [IPR021151]	0.4810749432248191	0.065621895556564	0.947678856550787	1.0	0.998052138556834	2	Q9BRX5	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.4806964420893204	0.0653679970147265	0.9478810042463376	1.0	0.998052138556834	2	Q96CW5	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.4806964420893204	0.0653679970147265	0.9478810042463376	1.0	0.998052138556834	2	Q96CW5	1
+Glycoside hydrolase family 38, N-terminal domain [IPR000602]	0.4750189250567644	0.0616999969433231	0.950801742405306	1.0	0.998052138556834	2	Q16706	1
+Glycosyl hydrolase family 38, C-terminal [IPR011682]	0.4750189250567644	0.0616999969433231	0.950801742405306	1.0	0.998052138556834	2	Q16706	1
+Glycoside hydrolase family 38, central domain [IPR015341]	0.4750189250567644	0.0616999969433231	0.950801742405306	1.0	0.998052138556834	2	Q16706	1
+Dynamin stalk domain [IPR000375]	0.4731264193792492	0.0605348128969317	0.9517296899960156	1.0	0.998052138556834	2	P50570	1
+GTPase effector domain [IPR020850]	0.4731264193792492	0.0605348128969317	0.9517296899960156	1.0	0.998052138556834	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.4731264193792492	0.0605348128969317	0.9517296899960156	1.0	0.998052138556834	2	P50570	1
+Cyclin, C-terminal domain [IPR004367]	0.4602573807721311	0.0533371908674396	0.9574632483342032	1.0	0.998052138556834	2	P14635	1
+Cyclin, N-terminal [IPR006671]	0.4602573807721311	0.0533371908674396	0.9574632483342032	1.0	0.998052138556834	2	P14635	1
+Exportin-1/Importin-beta-like [IPR013598]	0.2863636363636386	0.0483582620732004	0.961430722404292	1.0	0.998052138556834	4	O14980,O43592,Q9HAV4	3
+CAP Gly-rich domain [IPR000938]	0.2859848484848509	0.0480473801207343	0.961678482309586	1.0	0.998052138556834	4	Q14203,P30622,Q99426	3
+GRAM domain [IPR004182]	0.4473883421650188	0.0473162752351893	0.9622611568487014	1.0	0.998052138556834	2	Q66K14	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.2844696969697012	0.0468221155893605	0.9626550026704276	1.0	0.998052138556834	4	Q4J6C6,P13798,Q86TI2	3
+Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]	0.2780303030303092	0.0419337556528261	0.966551506935888	1.0	0.998052138556834	4	P36915,Q9NVN8,Q13823	3
+G-protein, beta subunit [IPR001632]	0.4299772899318651	0.0408195387788984	0.9674397626466896	1.0	0.998052138556834	2	Q9NVX2	1
+Pleckstrin homology domain, spectrin-type [IPR001605]	0.4250567751703196	0.039289171294381	0.9686598400069352	1.0	0.998052138556834	2	O15020	1
+Pleckstrin homology domain 9 [IPR041681]	0.4250567751703196	0.039289171294381	0.9686598400069352	1.0	0.998052138556834	2	O15020	1
+EF hand associated, type-2 [IPR013567]	0.4148372445117218	0.0364924340393356	0.9708897114548372	1.0	0.998052138556834	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.4148372445117218	0.0364924340393356	0.9708897114548372	1.0	0.998052138556834	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.4148372445117218	0.0364924340393356	0.9708897114548372	1.0	0.998052138556834	2	Q8IXI2	1
+MCM, AAA-lid domain [IPR041562]	0.324109173616369	0.0350241580021306	0.9720604773882138	1.0	0.998052138556834	6	P25205,P33991,P49736,Q14566,P33993	5
+MCM domain [IPR001208]	0.324109173616369	0.0350241580021306	0.9720604773882138	1.0	0.998052138556834	6	P25205,P33991,P49736,Q14566,P33993	5
+MCM N-terminal domain [IPR027925]	0.324109173616369	0.0350241580021306	0.9720604773882138	1.0	0.998052138556834	6	P25205,P33991,P49736,Q14566,P33993	5
+MCM OB domain [IPR033762]	0.324109173616369	0.0350241580021306	0.9720604773882138	1.0	0.998052138556834	6	P25205,P33991,P49736,Q14566,P33993	5
+FATC domain [IPR003152]	0.4049962149886381	0.0342401814837177	0.9726856251227638	1.0	0.998052138556834	2	P42345	1
+PIK-related kinase [IPR014009]	0.4049962149886381	0.0342401814837177	0.9726856251227638	1.0	0.998052138556834	2	P42345	1
+PIK-related kinase, FAT [IPR003151]	0.4049962149886381	0.0342401814837177	0.9726856251227638	1.0	0.998052138556834	2	P42345	1
+Staufen, C-terminal [IPR032478]	0.2866338508140891	0.0322496403457983	0.9742729694744028	1.0	0.998052138556834	3	O75569,O95793	2
+Methylglyoxal synthase-like domain [IPR011607]	0.376987130961382	0.0297506597820374	0.9762659091187752	1.0	0.998052138556834	2	P31939	1
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.3652535957607789	0.0285309792357821	0.977238660223806	1.0	0.998052138556834	2	P12956	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.3652535957607789	0.0285309792357821	0.977238660223806	1.0	0.998052138556834	2	P12956	1
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.3652535957607789	0.0285309792357821	0.977238660223806	1.0	0.998052138556834	2	P12956	1
+Pentacotripeptide-repeat region of PRORP [IPR033443]	0.3266464799394334	0.0262802701494964	0.9790337916161492	1.0	0.998052138556834	2	P42704	1
+Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]	0.3228614685843992	0.0261606710494167	0.9791291850937632	1.0	0.998052138556834	2	Q5JTZ9	1
+Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]	0.3228614685843992	0.0261606710494167	0.9791291850937632	1.0	0.998052138556834	2	Q5JTZ9	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.3186979560938616	0.0260435676010263	0.9792225883030105	1.0	0.998052138556834	2	Q9Y678	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.3186979560938616	0.0260435676010263	0.9792225883030105	1.0	0.998052138556834	2	Q9Y678	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.998052138556834	2	P30876	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.998052138556834	2	P30876	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.998052138556834	2	P30876	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.998052138556834	2	P30876	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.2967448902346636	0.0256234316012363	0.9795576964890328	1.0	0.998052138556834	2	P30876	1
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.2928488887225131	0.0062830905017732	0.9949868520787256	1.0	1.0	5	Q9NTK5	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin [IPR000217]", "1": "Beta tubulin [IPR002453]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin [IPR000217]", "1": "Beta tubulin [IPR002453]", "2": "Mitochondrial carrier protein [IPR002067]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "4": "Mini-chromosome maintenance protein [IPR031327]"}