ligdis commited on
Commit
fede023
·
verified ·
1 Parent(s): ee56db0

Upload folder using huggingface_hub

Browse files
This view is limited to 50 files because it contains too many changes.   See raw diff
Files changed (50) hide show
  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +3 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/consensus.joblib +3 -0
  12. interpro_binding_site/df_merge.tsv +1 -0
  13. interpro_binding_site/metrics.json +7 -0
  14. interpro_binding_site/paths.json +1 -0
  15. interpro_binding_site/result.tsv +3 -0
  16. interpro_binding_site/selections.json +1 -0
  17. interpro_conserved_site/advanced/idx2term.json +1 -0
  18. interpro_conserved_site/basic/idx2term.json +1 -0
  19. interpro_conserved_site/basic/plot_0.png +3 -0
  20. interpro_conserved_site/basic/plot_1.png +3 -0
  21. interpro_conserved_site/consensus.joblib +3 -0
  22. interpro_conserved_site/df_merge.tsv +1 -0
  23. interpro_conserved_site/metrics.json +7 -0
  24. interpro_conserved_site/paths.json +1 -0
  25. interpro_conserved_site/result.tsv +18 -0
  26. interpro_conserved_site/selections.json +1 -0
  27. interpro_domain/advanced/idx2term.json +1 -0
  28. interpro_domain/basic/idx2term.json +1 -0
  29. interpro_domain/basic/plot_0.png +3 -0
  30. interpro_domain/basic/plot_1.png +3 -0
  31. interpro_domain/basic/plot_2.png +3 -0
  32. interpro_domain/basic/plot_3.png +3 -0
  33. interpro_domain/basic/plot_4.png +3 -0
  34. interpro_domain/basic/plot_5.png +3 -0
  35. interpro_domain/basic/plot_6.png +3 -0
  36. interpro_domain/consensus.joblib +3 -0
  37. interpro_domain/df_merge.tsv +4 -0
  38. interpro_domain/metrics.json +7 -0
  39. interpro_domain/paths.json +1 -0
  40. interpro_domain/result.tsv +158 -0
  41. interpro_domain/selections.json +0 -0
  42. interpro_family/advanced/idx2term.json +1 -0
  43. interpro_family/advanced/plot_0.png +3 -0
  44. interpro_family/basic/idx2term.json +1 -0
  45. interpro_family/basic/plot_0.png +3 -0
  46. interpro_family/basic/plot_1.png +3 -0
  47. interpro_family/basic/plot_2.png +3 -0
  48. interpro_family/consensus.joblib +3 -0
  49. interpro_family/df_merge.tsv +2 -0
  50. interpro_family/metrics.json +7 -0
interpro_active_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_active_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_active_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:452fed22423ea876c5dce40da176d60f9ebf99c08cdcd6d7b62707d5e6c07cc4
3
+ size 60558
interpro_active_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2644,
4
+ "annotations_size": 53,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.452830188679245
7
+ }
interpro_active_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C199/C199_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ ATP:guanido phosphotransferase active site [IPR022415] 0.767600302800904 0.4631693096513796 0.6432430128187203 1.0 0.8741507610100558 2 P12277 1
3
+ Glycosyl hydrolases family 31, active site [IPR030458] 0.6214988644965871 0.1624723084380431 0.870933933193395 1.0 1.0 2 P10253 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME6", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1"], "leading_proteins": ["CKB", "GAA"]}
interpro_binding_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_binding_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_binding_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:ab544fb82ddabce0a1904c5b25c4ea41d473b03d2867f9050e1cc7bf0931d836
3
+ size 59452
interpro_binding_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2644,
4
+ "annotations_size": 27,
5
+ "title": "Average number of proteins per term",
6
+ "value": 4.555555555555555
7
+ }
interpro_binding_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C199/C199_val_log2fc"}
interpro_binding_site/result.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Peptidase M16, zinc-binding site [IPR001431] 0.8024966921334947 1.84780242126474 0.0646309305290593 0.8353578130083508 0.3228115907667596 5 Q10713,O43847 2
3
+ EF-Hand 1, calcium-binding site [IPR018247] 0.3162193696235743 0.0736705355127075 0.9412725443146588 1.0 0.9412725443146588 38 Q9NWM8,Q9Y680,P80303,Q14257 4
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHUK", "COX2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP14", "FKBP7", "NRDC", "NUCB2", "PMPCA", "RCN2"]}
interpro_conserved_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_conserved_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]"}
interpro_conserved_site/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 5fd14e98be4916d7bd05bb3c0b1c83d2b2166530d86b90a2e6c1a97a7d10acd9
  • Pointer size: 131 Bytes
  • Size of remote file: 133 kB
interpro_conserved_site/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 1673be2fa2fb0122b8fd108c2d2db1269e19b5fbc5abb67ce6cfacf7041fdc18
  • Pointer size: 131 Bytes
  • Size of remote file: 140 kB
interpro_conserved_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:6a06a260b67425d5756796cf973911087171b226f6d8bbbe16e3ab06b3ef2595
3
+ size 69112
interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2644,
4
+ "annotations_size": 265,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.4754716981132074
7
+ }
interpro_conserved_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C199/C199_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,18 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.7627542911611014 1.9363197916636137 0.0528285462539523 0.9999994330050828 0.468621052140898 8 P20618,P49721,P28070,P28072,P28074 5
3
+ ABC transporter-like, conserved site [IPR017871] 0.7364866673486188 1.7837147453740174 0.0744700288812911 0.9999999987598364 0.468621052140898 7 P08183 1
4
+ Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.7202409454467921 1.6805148717994003 0.0928571832505138 0.999999999993918 0.4732144915651186 6 P30837,P49189,P51648 3
5
+ Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.8016227715459645 1.6707007811447274 0.0947807945078249 0.9999999999965348 0.4732248705471498 4 P40939 1
6
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.9125331313896324 1.4433495584991205 0.1489220257537016 1.0 0.5345795291821174 3 Q99536,Q08257 2
7
+ Intermediate filament protein, conserved site [IPR018039] 0.6389528568671712 1.3728420300120918 0.1698014613643224 1.0 0.5424616455000413 8 P02545,P48681,Q16352,P08670,P07196 5
8
+ Chromo domain, conserved site [IPR023779] 0.683274089987519 1.1833335999523389 0.2366769615058555 1.0 0.6815502774772403 4 Q14781,P45973 2
9
+ Haem oxygenase conserved site [IPR018207] 0.944360333080998 1.018391697486506 0.3084918462291757 1.0 0.7585808889687139 2 P30519 1
10
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.931491294473882 0.97421308146694 0.3299507507642252 1.0 0.763970120640325 2 P40939 1
11
+ Sterol reductase, conserved site [IPR018083] 0.9038607115821332 0.8806756493037007 0.3784934002637583 1.0 0.7837919912515529 2 Q14739 1
12
+ Thioredoxin, conserved site [IPR017937] 0.4390286877025738 0.4774498463562575 0.6330418264861191 1.0 0.9453428613792304 10 O95881,Q9H3N1,Q8IXB1,Q9H1E5 4
13
+ Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.4195246963356172 0.3689690030171108 0.7121508291886105 1.0 0.9985183583861472 6 P30837,P51648 2
14
+ Cyclic nucleotide-binding, conserved site [IPR018488] 0.7032551097653251 0.3068610542663283 0.758949133970638 1.0 1.0 2 P13861 1
15
+ Glycosyl hydrolases family 31, conserved site [IPR030459] 0.6214988644965871 0.1624723084380431 0.870933933193395 1.0 1.0 2 P10253 1
16
+ Ribosomal S11, conserved site [IPR018102] 0.50302800908402 0.062066321236612 0.950510017029058 1.0 1.0 2 P82912 1
17
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.3709311127933333 0.0398944485086895 0.9681772770297314 1.0 1.0 2 P82675 1
18
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.3479742521772076 0.037071866644424 0.9704277037686422 1.0 1.0 3 Q9BXS5,Q9Y2T2 2
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ARIH2", "ARSA", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP6", "MPST", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF8", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIF", "PPIG", "PPIH", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ALDH1B1", "ALDH3A2", "ALDH9A1", "AP1M1", "AP3M1", "CBX2", "CBX5", "CRYZ", "DNAJC10", "GAA", "HADHA", "HMOX2", "INA", "LBR", "LMNA", "MRPS11", "MRPS5", "NEFL", "NES", "PRKAR2A", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "TMX1", "TMX4", "TXNDC12", "VAT1", "VIM"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "K Homology domain, type 1 [IPR004088]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "K Homology domain [IPR004087]", "3": "Chromo/chromo shadow domain [IPR000953]", "4": "Thioredoxin domain [IPR013766]", "5": "SPRY domain [IPR003877]", "6": "B30.2/SPRY domain [IPR001870]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 76c7f661ed282638f7a507adaca203bcbe9e20b68e9012263ea10654c1bc74a1
  • Pointer size: 131 Bytes
  • Size of remote file: 133 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: ebf2a3561da9ccf5d5ef1c37c347435e71a5b59b41dbbb38c275e7e15bab51c0
  • Pointer size: 131 Bytes
  • Size of remote file: 137 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 7152b8d6f28d7fce8e65e214d41577688f8179cf1b322544b2dcf8f626811121
  • Pointer size: 131 Bytes
  • Size of remote file: 131 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: 298b4bcffe4095333151256ebb27bf5e816d3c3fcd620df054b7dd09fa549174
  • Pointer size: 131 Bytes
  • Size of remote file: 145 kB
interpro_domain/basic/plot_4.png ADDED

Git LFS Details

  • SHA256: 6e70ec6e647804f3e317e088c70749f81561024edf78ea4a1f752046cf0f7ec0
  • Pointer size: 131 Bytes
  • Size of remote file: 147 kB
interpro_domain/basic/plot_5.png ADDED

Git LFS Details

  • SHA256: 686d927720fd5014eac5fd8dda3d68e9b67c5cc290fe25e34c7768634c41d71e
  • Pointer size: 131 Bytes
  • Size of remote file: 144 kB
interpro_domain/basic/plot_6.png ADDED

Git LFS Details

  • SHA256: cf1e3af64f14071417f02f1ac13e84ff2712b28b808406d261619c21faee0a84
  • Pointer size: 131 Bytes
  • Size of remote file: 148 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:e6b4187a840b028a9382a641876f149228f634779224b69bb36f61e0a70bf0d7
3
+ size 140727
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 5 2.333335861014737 0.0196305246965187 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.0 0.0014481500629001 0.0001725606130307 5.306786809041431e-06 0.0001560226497295
3
+ Peptidase M16, C-terminal [IPR007863] 3 7 2.007970083517766 0.0446464708270948 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 1.0 1.0 0.0647424502180396 1.075765402375085e-05 0.0001695148193701
4
+ Peptidase M16, N-terminal [IPR011765] 3 7 2.007970083517766 0.0446464708270948 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 1.0 1.0 0.0647424502180396 1.075765402375085e-05 0.0001695148193701
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2644,
4
+ "annotations_size": 2312,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.0666089965397925
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C199/C199_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,158 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9219401288366824 2.3333358610147372 0.0196305246965187 1.0 0.5472844228166686 5 O15173,Q9UMX5,Q8WUJ1,O43169 4
3
+ Peptidase M16, C-terminal [IPR007863] 0.787857840769706 2.007970083517766 0.0446464708270948 1.0 0.5472844228166686 7 Q10713,O43847,Q5JRX3 3
4
+ Peptidase M16, N-terminal [IPR011765] 0.787857840769706 2.007970083517766 0.0446464708270948 1.0 0.5472844228166686 7 Q10713,O43847,Q5JRX3 3
5
+ Alcohol dehydrogenase, N-terminal [IPR013154] 0.8383794630554915 1.8200395815124728 0.0687529773770152 1.0 0.5472844228166686 4 Q99536,Q08257 2
6
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.7364866673486188 1.7837147453740174 0.0744700288812911 1.0 0.5472844228166686 7 P08183 1
7
+ Polyketide synthase, enoylreductase domain [IPR020843] 0.7737552335796624 1.7274835854003223 0.0840808506433978 1.0 0.5472844228166686 5 Q99536,Q08257 2
8
+ Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.7251573473298131 1.7020059239717231 0.08875425776909 1.0 0.553580637433307 6 Q8N8N7,Q08257 2
9
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9663006436955696 1.6470243390248838 0.0995530431970774 1.0 0.5697193957218889 3 Q96CP7,Q15629 2
10
+ K Homology domain, type 1 [IPR004088] 0.542438530654834 1.5869174954671488 0.1125313319007512 1.0 0.5913266338146732 22 Q9Y2W6,P61978,Q96I24,Q96PU8,Q92945,Q06787,P51116,Q9Y6M1,Q9NQT5,Q07666,Q96AE4,Q13868 12
11
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.9317555425427256 1.51624571360542 0.1294572328382908 1.0 0.62431608222687 3 P08183 1
12
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6501729192319181 1.4569233790771667 0.14513753170483 1.0 0.6650294269125203 9 Q96AY3,Q9NWM8,P62942,Q9Y680 4
13
+ Zinc finger, CHHC-type [IPR012996] 0.909503975766754 1.4318601715340429 0.1521838426724058 1.0 0.6711178398596813 3 P31943,P52597 2
14
+ Intermediate filament, rod domain [IPR039008] 0.6389528568671712 1.3728420300120918 0.1698014613643224 1.0 0.6868779331901342 8 P02545,P48681,Q16352,P08670,P07196 5
15
+ K Homology domain [IPR004087] 0.5096075695472438 1.370968171265927 0.170384878283623 1.0 0.6873570086473781 22 Q9Y2W6,P61978,Q96I24,Q96PU8,Q92945,Q06787,P51116,Q9Y6M1,Q07666,Q96AE4 10
16
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.6667875072839169 1.2710179891935367 0.2037222489473102 1.0 0.7393392991003357 5 P55786 1
17
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.6667875072839169 1.2710179891935367 0.2037222489473102 1.0 0.7393392991003357 5 P55786 1
18
+ Glutathione S-transferase, N-terminal [IPR004045] 0.6186147143070666 1.2284911281824349 0.2192626577743306 1.0 0.7464621373671868 6 Q9H7Z7 1
19
+ ERAP1-like C-terminal domain [IPR024571] 0.8549656525382965 1.225378841689879 0.2204325150857953 1.0 0.7464621373671868 3 P55786 1
20
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.6474621318625056 1.187780982124941 0.2349197088759642 1.0 0.7633768488829781 5 Q9HD20 1
21
+ Zinc finger, RanBP2-type [IPR001876] 0.596408066541279 1.1740455141418409 0.2403767956546101 1.0 0.7696518578914906 8 Q01844,Q92804 2
22
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.8333964407421439 1.1442246148928392 0.2525304973930342 1.0 0.7736592959796512 3 Q9BYT8,Q99797 2
23
+ Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.6722725473949017 1.1380362466973015 0.2551053472693767 1.0 0.7773383695752205 4 Q4J6C6 1
24
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.6718610616644579 1.136343933347746 0.2558126506967282 1.0 0.7773383695752205 4 P08670,P07196 2
25
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9689629068887204 1.1037264083741396 0.2697118363766131 1.0 0.7923427772588685 2 Q13505 1
26
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.9689629068887204 1.1037264083741396 0.2697118363766131 1.0 0.7923427772588685 2 Q13505 1
27
+ FAD linked oxidase, N-terminal [IPR006094] 0.9655563966691894 1.0918501263867306 0.2748989822291756 1.0 0.7949680701670103 2 Q15392 1
28
+ FAD-binding domain, PCMH-type [IPR016166] 0.9655563966691894 1.0918501263867306 0.2748989822291756 1.0 0.7949680701670103 2 Q15392 1
29
+ Reticulon [IPR003388] 0.948523845571536 1.032756881713239 0.3017176867427968 1.0 0.8185307639665025 2 O95197 1
30
+ GNAT domain [IPR000182] 0.645961708457373 1.030215607249774 0.3029088048367523 1.0 0.8190937506228905 4 Q86UY6 1
31
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6451696096414057 1.0269844837345632 0.3044277704112346 1.0 0.8212800527313593 4 Q32P28 1
32
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6451696096414055 1.0269844837345627 0.3044277704112348 1.0 0.8212800527313593 4 Q32P28 1
33
+ Tudor domain [IPR002999] 0.5736781972270192 1.026097372900266 0.3048456884939603 1.0 0.8214489881095993 6 Q9Y2W6,Q14739 2
34
+ Major facilitator superfamily domain [IPR020846] 0.7981247171500055 1.012785577708783 0.3111625909804854 1.0 0.8242916951550067 3 P53985 1
35
+ Lamin tail domain [IPR001322] 0.7913669064748253 0.9878472654391074 0.323227455358323 1.0 0.8320048228961638 3 Q03252,P02545 2
36
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.931491294473882 0.97421308146694 0.3299507507642252 1.0 0.8392879105227585 2 P40939 1
37
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.931491294473882 0.97421308146694 0.3299507507642252 1.0 0.8392879105227585 2 P40939 1
38
+ Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.7844845573370567 0.9625485374505576 0.3357741340489657 1.0 0.8392879105227585 3 P16435 1
39
+ FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.7844845573370567 0.9625485374505576 0.3357741340489657 1.0 0.8392879105227585 3 P16435 1
40
+ Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.7844845573370567 0.9625485374505576 0.3357741340489657 1.0 0.8392879105227585 3 P16435 1
41
+ Acyl-CoA oxidase, C-terminal [IPR002655] 0.9250567751703236 0.9522602019613798 0.3409650361264942 1.0 0.8392879105227585 2 O15254 1
42
+ NOPS [IPR012975] 0.7800075728890565 0.946149384277264 0.3440723983761728 1.0 0.8410541847130056 3 P23246,Q15233 2
43
+ Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.6184199019158424 0.9185815827910124 0.3583144687918527 1.0 0.8602523902873971 4 Q01658 1
44
+ Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.7530739266106937 0.8486030190173666 0.3961022265014602 1.0 0.882370677722735 3 Q96EY1 1
45
+ LEM domain [IPR003887] 0.5216039772849221 0.7935381076559871 0.4274643760618608 1.0 0.8933750045438575 6 P50402,Q86XL3 2
46
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.7359066197692764 0.7876081589523023 0.4309259407921715 1.0 0.8933750045438575 3 P10321 1
47
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7359066197692764 0.7876081589523023 0.4309259407921715 1.0 0.8933750045438575 3 P10321 1
48
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8716881150643455 0.7745782874258793 0.4385888914183242 1.0 0.8940124721203723 2 O60506 1
49
+ Zinc finger C2H2 AKAP95-type [IPR034736] 0.7304051495645615 0.7682897745060411 0.4423150482824405 1.0 0.8970459575693004 3 Q9ULX6,Q5BKZ1 2
50
+ ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8690386071158217 0.7660007723928897 0.4436758426001339 1.0 0.8990171324202538 2 Q5T9A4 1
51
+ SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.726467807835862 0.7545375823275398 0.4505264872931258 1.0 0.9040833766675525 3 Q96P11 1
52
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8633610900832693 0.7477112258497028 0.454634358495162 1.0 0.9064955556790922 2 Q32P28 1
53
+ PI31 proteasome regulator, N-terminal [IPR021625] 0.852763058289173 0.7139181322075305 0.4752778044549595 1.0 0.9195332919664154 2 Q92530 1
54
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7100023271393868 0.6977479122369836 0.4853348589675654 1.0 0.9265848009356 3 P16615 1
55
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7100023271393868 0.6977479122369836 0.4853348589675654 1.0 0.9265848009356 3 P16615 1
56
+ Guanylate kinase-like domain [IPR008144] 0.6979668068538875 0.6570441522726554 0.511152527113629 1.0 0.953402436603694 3 Q9NZW5 1
57
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.6979668068538875 0.6570441522726554 0.511152527113629 1.0 0.953402436603694 3 Q9NZW5 1
58
+ RBM3/CIRBP, RNA recognition motif [IPR034278] 0.825510976532928 0.6293275225837781 0.5291346564905743 1.0 0.953402436603694 2 P98179 1
59
+ Marvel domain [IPR008253] 0.8236184708554094 0.6235880359933333 0.5328981697588118 1.0 0.953402436603694 2 Q16625 1
60
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4768903121685467 0.6209062413882355 0.534661314346053 1.0 0.953402436603694 8 O15254,Q15067 2
61
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.6819386595986359 0.6040306049639131 0.5458232947617925 1.0 0.953402436603694 3 P51116,Q06787 2
62
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.6819386595986359 0.6040306049639131 0.5458232947617925 1.0 0.953402436603694 3 P51116,Q06787 2
63
+ Fxr1, tudor domain [IPR041560] 0.6819386595986359 0.6040306049639131 0.5458232947617925 1.0 0.953402436603694 3 P51116,Q06787 2
64
+ Agenet-like domain [IPR008395] 0.6819386595986359 0.6040306049639131 0.5458232947617925 1.0 0.953402436603694 3 P51116,Q06787 2
65
+ Oxidoreductase, N-terminal domain [IPR041694] 0.8141559424678235 0.5951759308786849 0.5517258773406468 1.0 0.953402436603694 2 Q8N8N7 1
66
+ CARG-binding factor, N-terminal [IPR012956] 0.8137774413323229 0.5940495815880124 0.5524789512782613 1.0 0.953402436603694 2 Q99729 1
67
+ Chromo shadow domain [IPR008251] 0.6698522628858338 0.565052557986884 0.5720380160352516 1.0 0.956757858628736 3 P45973 1
68
+ Chromo domain subgroup [IPR017984] 0.6698522628858338 0.565052557986884 0.5720380160352516 1.0 0.956757858628736 3 P45973 1
69
+ HDGF-related, PWWP domain [IPR035496] 0.6698220371071619 0.5649562322606019 0.5721035343091296 1.0 0.956757858628736 3 Q7Z4V5,P51858 2
70
+ PTBP1, RNA recognition motif 2-like [IPR021790] 0.5222626274462763 0.5503816334300515 0.5820576433729687 1.0 0.958019335746344 4 Q8WVV9 1
71
+ LEM-like domain [IPR013146] 0.791824375473124 0.5301433339583983 0.5960125560512453 1.0 0.9630707603977816 2 P42167 1
72
+ Chromo domain [IPR023780] 0.485291162987025 0.5153596919378655 0.606301693867983 1.0 0.9643825549112204 5 Q14781,P45973 2
73
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.7850113550340634 0.5109115052235605 0.6094130245351612 1.0 0.9643825549112204 2 Q92945 1
74
+ Band 7 domain [IPR001107] 0.4504852855889963 0.5052540895909269 0.613380384112058 1.0 0.967446890966334 8 O75477 1
75
+ ATP:guanido phosphotransferase, N-terminal [IPR022413] 0.767600302800904 0.4631693096513796 0.6432430128187203 1.0 0.9855508955579904 2 P12277 1
76
+ ATP:guanido phosphotransferase, catalytic domain [IPR022414] 0.767600302800904 0.4631693096513796 0.6432430128187203 1.0 0.9855508955579904 2 P12277 1
77
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7638152914458701 0.453070893944862 0.6504976931753863 1.0 0.9855508955579904 2 Q7L576 1
78
+ Tim44-like domain [IPR007379] 0.7619227857683541 0.4480606448538551 0.6541094297060046 1.0 0.988432027111296 2 O43615 1
79
+ Cyclic nucleotide-binding domain [IPR000595] 0.4911254315835031 0.4436894312483703 0.6572671376119437 1.0 0.989968483491084 4 P13861,P10644 2
80
+ Peptidase M41 [IPR000642] 0.7539742619227832 0.4273072251727611 0.669155570953508 1.0 0.9934477260517062 2 Q96TA2 1
81
+ Chromo/chromo shadow domain [IPR000953] 0.4334470989761037 0.4269025863599581 0.6694502816515266 1.0 0.9934477260517062 7 Q8TAQ2,P83916,Q13185,P45973,Q92922,Q14781 6
82
+ Zinc finger, ZZ-type [IPR000433] 0.7509462528387549 0.4195266132787469 0.6748313090623212 1.0 0.9945544630752008 2 Q13501 1
83
+ Dynamin, N-terminal [IPR045063] 0.4238063905553622 0.3852090746922374 0.7000825205316827 1.0 0.9956389374795198 6 O95140 1
84
+ Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.4238063905553622 0.3852090746922374 0.7000825205316827 1.0 0.9956389374795198 6 O95140 1
85
+ Brix domain [IPR007109] 0.4636363636363724 0.3572535783342227 0.7209019790143301 1.0 0.9956389374795198 4 Q9NQ55,Q9H7B2,Q96G21 3
86
+ GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.7210446631339857 0.3466266159184862 0.728871847602901 1.0 0.9956389374795198 2 Q9HCL2 1
87
+ Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.7210446631339857 0.3466266159184862 0.728871847602901 1.0 0.9956389374795198 2 Q9HCL2 1
88
+ Immunoglobulin I-set [IPR013098] 0.7127176381529104 0.3276639618048045 0.7431657546648458 1.0 0.9956389374795198 2 Q13308 1
89
+ Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.7070401211203592 0.3150857499161323 0.752696547797538 1.0 0.9956389374795198 2 A1L0T0 1
90
+ Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.7070401211203592 0.3150857499161323 0.752696547797538 1.0 0.9956389374795198 2 A1L0T0 1
91
+ Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.7070401211203592 0.3150857499161323 0.752696547797538 1.0 0.9956389374795198 2 A1L0T0 1
92
+ cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.7032551097653251 0.3068610542663283 0.758949133970638 1.0 0.9956389374795198 2 P13861 1
93
+ Major sperm protein (MSP) domain [IPR000535] 0.5751609238924626 0.2987103855882513 0.7651610321068945 1.0 0.9956389374795198 3 Q9P0L0,Q8NHP6 2
94
+ Aldehyde dehydrogenase domain [IPR015590] 0.3976984183364612 0.2953261962157438 0.7677447067890917 1.0 0.9956389374795198 9 P30837,P49189,P51648,Q8IZ83 4
95
+ Immunoglobulin subtype 2 [IPR003598] 0.4296405958999507 0.2626118415049537 0.7928497721340766 1.0 0.9956389374795198 4 Q13308,P35613 2
96
+ Immunoglobulin subtype [IPR003599] 0.4296405958999507 0.2626118415049537 0.7928497721340766 1.0 0.9956389374795198 4 Q13308,P35613 2
97
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.6816805450416302 0.2625012640912699 0.7929350109168525 1.0 0.9956389374795198 2 P51116 1
98
+ Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333] 0.6809235427706235 0.2610241786731382 0.79407386154807 1.0 0.9956389374795198 2 Q9UHQ9 1
99
+ Pleckstrin homology domain, spectrin-type [IPR001605] 0.678652535957603 0.2566257290062346 0.7974677111309687 1.0 0.9956389374795198 2 Q01082 1
100
+ Pleckstrin homology domain 9 [IPR041681] 0.678652535957603 0.2566257290062346 0.7974677111309687 1.0 0.9956389374795198 2 Q01082 1
101
+ Legume-like lectin [IPR005052] 0.6767600302800859 0.2529980463178604 0.8002697229112414 1.0 0.9956389374795198 2 P49257 1
102
+ Peptidase M20, dimerisation domain [IPR011650] 0.6744890234670655 0.2486902092944659 0.8036004228108828 1.0 0.9956389374795198 2 Q8IYS1 1
103
+ Class II aldolase/adducin N-terminal [IPR001303] 0.6684330052990108 0.2374458628395393 0.8123109134549267 1.0 0.9956389374795198 2 Q9UEY8 1
104
+ SKP1 component, POZ domain [IPR016073] 0.6585919757759218 0.2199338772312639 0.8259226519874787 1.0 0.9956389374795198 2 P63208 1
105
+ CTP synthase, N-terminal [IPR017456] 0.6563209689629014 0.2160270860701331 0.8289666343888906 1.0 0.9956389374795198 2 Q9NRF8 1
106
+ CTP synthase GATase domain [IPR033828] 0.6563209689629014 0.2160270860701331 0.8289666343888906 1.0 0.9956389374795198 2 Q9NRF8 1
107
+ GRAM domain [IPR004182] 0.6430734292202818 0.194247551677354 0.8459820510316842 1.0 0.9956389374795198 2 Q66K14 1
108
+ Small-subunit processome, Utp12 [IPR007148] 0.5183642559636383 0.1819382980471212 0.8556311485588695 1.0 0.9956389374795198 3 Q15061,Q9UNX4 2
109
+ Myosin tail [IPR002928] 0.5157137447936369 0.1773982782340421 0.8591955596398035 1.0 0.9956389374795198 3 P35580,P35579 2
110
+ CRAL-TRIO lipid binding domain [IPR001251] 0.6252838758516213 0.167716967601861 0.866805947058366 1.0 0.9956389374795198 2 O75962 1
111
+ Glycoside hydrolase family 31, N-terminal domain [IPR025887] 0.6214988644965871 0.1624723084380431 0.870933933193395 1.0 0.9956389374795198 2 P10253 1
112
+ Disulphide isomerase [IPR005788] 0.3728685107995479 0.1582472816657058 0.8742619477209457 1.0 0.9956389374795198 5 P07237,Q8NBS9,Q15084,P30101 4
113
+ Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.6120363361090018 0.1499692378509908 0.880788885379423 1.0 0.9956389374795198 2 O75694 1
114
+ Thioredoxin domain [IPR013766] 0.3193256541424519 0.1342342062209634 0.8932173780209662 1.0 0.9956389374795198 22 O43819,Q6ZRP7,O14530,Q8IXB1,O95881,Q9H1E5,Q9Y320 7
115
+ ELMO domain [IPR006816] 0.5987887963663818 0.1339066004199381 0.8934764309152572 1.0 0.9956389374795198 2 Q8IZ81 1
116
+ Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.5984102952308784 0.1334720338599819 0.8938200801062186 1.0 0.9956389374795198 2 Q9UID3 1
117
+ Ras-associating (RA) domain [IPR000159] 0.4755774327906078 0.1186993842345405 0.9055135244093764 1.0 0.9983534899544484 3 P55196,Q96L92 2
118
+ DZF domain [IPR006561] 0.3439393939393974 0.0966045753228734 0.9230404229104644 1.0 1.0 4 Q96KR1,Q12906,Q96SI9 3
119
+ Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4433926542976175 0.0847102156498853 0.9324917742484344 1.0 1.0 3 Q1KMD3,Q9BUJ2 2
120
+ Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.3295454545454565 0.0793642334066677 0.9367429164819572 1.0 1.0 4 P36915,Q9NVN8,Q13823 3
121
+ Ataxin-2, C-terminal [IPR009818] 0.5193035579106678 0.0695400861417088 0.9445597257383372 1.0 1.0 2 Q8WWM7 1
122
+ SMARCC, N-terminal [IPR032450] 0.5132475397426102 0.0665716977219119 0.9469226776929986 1.0 1.0 2 Q92922 1
123
+ SMARCC, C-terminal [IPR032451] 0.5132475397426102 0.0665716977219119 0.9469226776929986 1.0 1.0 2 Q92922 1
124
+ SMARCC, SWIRM-associated domain [IPR032448] 0.5132475397426102 0.0665716977219119 0.9469226776929986 1.0 1.0 2 Q92922 1
125
+ EF hand associated, type-2 [IPR013567] 0.5128690386071063 0.066393741610173 0.947064352682317 1.0 1.0 2 Q8IXI2 1
126
+ EF hand associated, type-1 [IPR013566] 0.5128690386071063 0.066393741610173 0.947064352682317 1.0 1.0 2 Q8IXI2 1
127
+ MIRO domain [IPR020860] 0.5128690386071063 0.066393741610173 0.947064352682317 1.0 1.0 2 Q8IXI2 1
128
+ Target SNARE coiled-coil homology domain [IPR000727] 0.3266388783630199 0.0647733819266536 0.9483544350769004 1.0 1.0 5 O15400,Q8IZP0,Q13190,Q9UNK0 4
129
+ Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.5075700227100585 0.0639930277034507 0.9489757785168538 1.0 1.0 2 Q96C36 1
130
+ Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.5075700227100585 0.0639930277034507 0.9489757785168538 1.0 1.0 2 Q96C36 1
131
+ G-protein, beta subunit [IPR001632] 0.5022710068130134 0.0617566225204076 0.9507566477275272 1.0 1.0 2 Q9NVX2 1
132
+ Longin domain [IPR010908] 0.4096932979931784 0.060131100830876 0.9520512198905238 1.0 1.0 3 P51809,O75396 2
133
+ v-SNARE, coiled-coil homology domain [IPR042855] 0.4096932979931784 0.060131100830876 0.9520512198905238 1.0 1.0 3 P51809,O75396 2
134
+ Ubiquitin system component CUE [IPR003892] 0.3059906403945151 0.0571421075426154 0.9544319942324692 1.0 1.0 4 Q9Y679 1
135
+ Ribosomal protein S7 domain [IPR023798] 0.4822104466313309 0.054653276611704 0.956414693551374 1.0 1.0 2 Q9Y2R9 1
136
+ Arf GTPase activating protein [IPR001164] 0.4644208932626687 0.0499271994724052 0.960180402283116 1.0 1.0 2 Q8N6H7 1
137
+ Armadillo repeat-containing domain [IPR006911] 0.4451173353519984 0.0461588181182736 0.963183665846681 1.0 1.0 2 Q8N2F6 1
138
+ Ran binding domain [IPR000156] 0.2875000000000015 0.0443570602307209 0.9646197889081698 1.0 1.0 4 Q9UKX7,P49792,Q9H6Z4 3
139
+ Ribosome receptor lysine/proline rich [IPR007794] 0.4288417865253521 0.0438628751914455 0.9650137081085376 1.0 1.0 2 Q86UP2 1
140
+ CTLH, C-terminal LisH motif [IPR006595] 0.4159727479182315 0.0425024445159846 0.966098163071048 1.0 1.0 2 Q96S59 1
141
+ NLE [IPR012972] 0.4133232399697074 0.0422646931147282 0.96628769093571 1.0 1.0 2 Q9NVX2 1
142
+ F-box domain [IPR001810] 0.2838015817264974 0.0422363137901093 0.9663103141592392 1.0 1.0 4 Q9Y3I1 1
143
+ Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.4049962149886346 0.0416001327790047 0.966817467392574 1.0 1.0 2 Q9UKA9 1
144
+ OCRE domain [IPR041591] 0.3773656320968855 0.0401175414273261 0.9679994170223196 1.0 1.0 2 P52756 1
145
+ Ribosomal protein S5, C-terminal [IPR005324] 0.3709311127933333 0.0398944485086895 0.9681772770297314 1.0 1.0 2 P82675 1
146
+ Ribosomal protein S5, N-terminal [IPR013810] 0.3709311127933333 0.0398944485086895 0.9681772770297314 1.0 1.0 2 P82675 1
147
+ Coatomer subunit gamma, C-terminal [IPR032154] 0.3474640423921215 0.0393427046154787 0.9686171595957712 1.0 1.0 2 Q9Y678 1
148
+ Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.3474640423921215 0.0393427046154787 0.9686171595957712 1.0 1.0 2 Q9Y678 1
149
+ APC10/DOC domain [IPR004939] 0.3334595003784941 0.0391538976390549 0.9687676897818048 1.0 1.0 2 Q9UM13 1
150
+ Dbl homology (DH) domain [IPR000219] 0.3483528966300649 0.0371502577228102 0.970365199793536 1.0 1.0 3 O75962,Q12802 2
151
+ Rho GTPase-activating protein domain [IPR000198] 0.3426732298371806 0.0360352778206079 0.971254229578723 1.0 1.0 3 Q9H0H5,Q68EM7 2
152
+ Nop domain [IPR002687] 0.3354789852328676 0.0347992498877108 0.972239818773554 1.0 1.0 3 Q9Y2X3,Q8WWY3 2
153
+ NOSIC [IPR012976] 0.3354789852328676 0.0347992498877108 0.972239818773554 1.0 1.0 3 Q9Y2X3,Q8WWY3 2
154
+ SPRY-associated [IPR006574] 0.3029155622870151 0.031153725385618 0.9751469437763663 1.0 1.0 3 Q14258,P19474 2
155
+ Butyrophylin-like, SPRY domain [IPR003879] 0.3029155622870151 0.031153725385618 0.9751469437763663 1.0 1.0 3 Q14258,P19474 2
156
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.2934395031925217 0.0095769447869688 0.992358820420449 1.0 1.0 6 P18031 1
157
+ SPRY domain [IPR003877] 0.3036053130929861 0.002793260146057 0.9977713037533158 1.0 1.0 9 Q00839,Q1KMD3,Q14258,P19474,Q92499,Q9BUJ2,Q96S59,Q9UBL3 8
158
+ B30.2/SPRY domain [IPR001870] 0.3036053130929861 0.002793260146057 0.9977713037533158 1.0 1.0 9 Q00839,Q1KMD3,Q14258,P19474,Q92499,Q9BUJ2,Q96S59,Q9UBL3 8
interpro_domain/selections.json ADDED
The diff for this file is too large to render. See raw diff
 
interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome B-type subunit [IPR023333]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: 2f8c832db25faa316e068030fef0b56ed3400272e94b866e1da67ef6f3495b1b
  • Pointer size: 131 Bytes
  • Size of remote file: 180 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "Mitochondrial carrier protein [IPR002067]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 4dc690732f7a5dc325e45f82a9c9216614fe669a31b64e0aef60e76ef4ad63e1
  • Pointer size: 131 Bytes
  • Size of remote file: 140 kB
interpro_family/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: db8213d367ce541d857bb318675d65cccd738350ae53ae8f198ad0a9d01c0152
  • Pointer size: 131 Bytes
  • Size of remote file: 140 kB
interpro_family/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 33e529bd54b7213882a31002fdb739d5e5bcb1c4a9a76b975d2518dfce475a1b
  • Pointer size: 131 Bytes
  • Size of remote file: 137 kB
interpro_family/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:286d8ea5518d80af2831622c48025d414cd4a1ad1f594661d6fded4de0cb7bce
3
+ size 183933
interpro_family/df_merge.tsv ADDED
@@ -0,0 +1,2 @@
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome B-type subunit [IPR023333] 5 7 2.0899940314487586 0.0366183358589022 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.0424464003246627 0.003087611696091 3.72798665310574e-05 9.308926617220138e-07
interpro_family/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2644,
4
+ "annotations_size": 2106,
5
+ "title": "Average number of proteins per term",
6
+ "value": 1.2730294396961064
7
+ }