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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Ubiquitin-conjugating enzyme, active site [IPR023313]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:9511d8062126f9ae2305d0da649457c627442858aab3e7dff1361a19ed1886a0
+size 64391

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2626,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.4339622641509435
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C200/C200_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.7028355351196638	0.7655537254328953	0.4439418874469027	0.999999999999969	0.6156875011151749	3	Q9H3G5	1
+Glycosyl hydrolases family 31, active site [IPR030458]	0.6600609756097637	0.7301364452469492	0.4653067859407136	0.999999999999996	0.6156875011151749	2	P10253	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.2572519083969496	0.0031481059244052	0.9974881790360756	1.0	0.9974881790360756	6	P68036,Q16763,P61081,P49427,P61088	5

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME6", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1"], "leading_proteins": ["CDC34", "CPVL", "GAA", "UBE2L3", "UBE2M", "UBE2N", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:334583a08013e07855139054b3bb085a84d7edfc7ff9e193b724a7e3d49ac706
+size 60312

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2626,
+    "annotations_size": 27,
+    "title": "Average number of proteins per term",
+    "value": 4.481481481481482
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C200/C200_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.6994939252319072	1.3133177075303244	0.1890759141449194	0.9965128920049542	0.3190656051195515	6	Q9BVA1,Q13885,P68371	3
+EF-Hand 1, calcium-binding site [IPR018247]	0.3695097780111294	1.0804185684642424	0.2799558308400682	0.9998591694996014	0.3780943505285072	38	O43852,Q14257,Q9Y680,Q96AY3,Q03001,Q02818	6
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.5552591463414746	0.3674261954299853	0.7133011348397835	0.9999999999999978	0.7407357938720829	2	P34897	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHUK", "COX2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "DST", "FKBP10", "FKBP7", "NUCB1", "RCN2", "SHMT2", "TUBB2A", "TUBB2B", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "WD40 repeat, conserved site [IPR019775]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:dcec9552cabe29ddfe09061fc2fab05dd91bb5a5799acd02aa48a60d781159c9
+size 94552

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Zinc finger, RING-type, conserved site [IPR017907]	4	12	2.373373781633775	0.0176264162619137	4.609223300970874	14.776699029126211	-0.045326225777209	0.5577732895844865	3.238903742779499	4.550007017672923	0.8841385018499901	0.2924846286854669	1.0	1.0	0.089654036835445	0.5325088576828272

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2626,
+    "annotations_size": 264,
+    "title": "Average number of proteins per term",
+    "value": 2.4734848484848486
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C200/C200_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Zinc finger, RING-type, conserved site [IPR017907]	0.7517846362307643	2.373373781633775	0.0176264162619137	0.9908579755774304	0.0925167296452234	12	Q99496,Q14527,P22681,P19474	4
+Sterol reductase, conserved site [IPR018083]	0.994283536585366	2.1080234271084324	0.0350289630629774	0.999918385089862	0.1243068175960816	2	Q9UBM7	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9908536585365856	2.0940429417101556	0.0362561551321904	0.9999416733566152	0.1243068175960816	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9908536585365856	2.0940429417101556	0.0362561551321904	0.9999416733566152	0.1243068175960816	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9908536585365856	2.0940429417101556	0.0362561551321904	0.9999416733566152	0.1243068175960816	2	P05067	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9500762195121965	1.9267511538680968	0.0540106495170542	0.9999995695038244	0.1584312385833591	2	Q9BTY2	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.9153640869233748	1.5539088383141204	0.12020616320163	0.999999999999998	0.26226799243992	3	P55899,P01889	2
+AT hook, DNA-binding motif [IPR017956]	0.8250762195121992	1.4048802853666935	0.1600568798905781	1.0	0.3239277832514542	2	P17096	1
+Tubulin, conserved site [IPR017975]	0.6994939252319072	1.3133177075303244	0.1890759141449194	1.0	0.3591082110378326	6	Q9BVA1,Q13885,P68371	3
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.8362509916271001	1.2561076858444338	0.2090769299135346	1.0	0.38039896774263	3	P09429	1
+Cadherin conserved site [IPR020894]	0.8353030880670989	1.2525427626530663	0.2103721564031211	1.0	0.38039896774263	3	Q14126,Q14574	2
+Thioredoxin, conserved site [IPR017937]	0.5481966307469751	1.214053714342062	0.2247272132221696	1.0	0.3932099422178388	10	Q8IXB1,O95881	2
+WD40 repeat, conserved site [IPR019775]	0.3691973009370459	1.1146589580456951	0.2649965948600288	1.0	0.4373297964616249	47	P43034,Q9NWT1,P31146,O75717,Q8TEQ6,Q14137,Q16576,Q9GZS3,Q9UFC0,Q12788,Q8NFH3,Q13685,P57737,Q9GZL7,Q09028,Q9BQ67,Q96DI7	17
+Calreticulin/calnexin, conserved site [IPR018124]	0.7750667174990514	1.0273998188080582	0.3042322367801966	1.0	0.4696918743273211	3	O14967,P27824	2
+Ribosomal protein L30, conserved site [IPR018038]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.5043778708347133	2	Q6DKI1	1
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.6600609756097637	0.7301364452469492	0.4653067859407136	1.0	0.5992243487236507	2	P10253	1
+DnaJ domain, conserved site [IPR018253]	0.4804010528304967	0.7194463543065536	0.4718659445411104	1.0	0.604721404654627	8	Q96EY1	1
+Chromo domain, conserved site [IPR023779]	0.5664426409259855	0.614273701446881	0.5390344778283758	1.0	0.6584221692012008	4	Q13185,P83916	2
+Intermediate filament protein, conserved site [IPR018039]	0.422241028184383	0.4737483526663787	0.6356793684048454	1.0	0.7392923051051946	8	P07196,P48681	2
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.5560213414634259	0.3696958696715728	0.7116091096311401	1.0	0.789347919926979	2	P24534	1
+Ribosomal protein L24e, conserved site [IPR023442]	0.5525914634146454	0.3595348118074588	0.7191950402796055	1.0	0.7944246470034135	2	Q9UHA3	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.49161585365855	0.2035842017799736	0.8386784397469074	1.0	0.9037188085436064	2	P82675	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]	0.3647381573704327	0.1324057074833753	0.8946634005057719	1.0	0.9300284138410904	6	Q13427	1
+Ribosomal protein L3, conserved site [IPR019926]	0.4294969512195213	0.0978237284385609	0.9220722651791656	1.0	0.9508870234660144	2	P39023	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.3015630956919579	0.0126811719374259	0.9898821598775244	1.0	0.9974385122430016	3	Q9P2W9,Q12846	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ARIH2", "ARSA", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDX2", "CETN2", "CHAF1B", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "ECH1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP6", "MPST", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF8", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIF", "PPIG", "PPIH", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RSL24D1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STX18", "STX4", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["AAMP", "APP", "BOP1", "CANX", "CBL", "CBX1", "CBX3", "CLGN", "CORO1A", "CORO7", "DHCR7", "DNAJA3", "DNAJC10", "DSC3", "DSG2", "EEF1B2", "FCGRT", "FUCA2", "GAA", "GEMIN5", "GRWD1", "HLA-B", "HLTF", "HMGA1", "HMGB1", "LRWD1", "MRPS5", "NEFL", "NES", "NUP43", "PAFAH1B1", "PAK1IP1", "PPIG", "RBBP4", "RBBP7", "RNF2", "RPL3", "RPL7L1", "RSL24D1", "SNRNP40", "STX18", "STX4", "TBL3", "TRIM21", "TUBB2A", "TUBB2B", "TUBB4B", "TXNDC12", "WDHD1", "WDR12", "WDR61"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Immunoglobulin-like domain [IPR007110]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Immunoglobulin-like domain [IPR007110]", "2": "EF-hand domain [IPR002048]", "3": "TGS [IPR004095]", "4": "Phosphoribosyltransferase domain [IPR000836]", "5": "Aminoacyl-tRNA synthetase, class II [IPR006195]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a99ccdc01285534a7fc3fa3b0c400c69a3bf4915403dc5e65c8390b84c21f10b
+size 370384

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+RNA recognition motif domain [IPR000504]	41	100	2.81169065647805	0.0049281874266571	39.713592233009706	116.0	0.2316956716939257	0.5316884276370477	13.873754985119357	5.729331786381952	1.713447249572458	0.3950212299678106	0.5706301526968064	0.025011328631119	1.4587030718068364e-05	4.35408899634496e-14
+Immunoglobulin-like domain [IPR007110]	5	8	2.611408949721765	0.0090169995198425	4.480582524271845	12.427184466019416	0.4075261998509777	0.4433674298264088	2.6479725987944898	3.173316973839475	1.1756568118942026	0.3233613924696422	0.4215392305763319	0.0927025470918742	0.0504044867766527	0.4554165110170887
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	5	1.987265908003208	0.0468929375248174	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0561990347849709	0.1084298440104649	0.0311746355924085	0.0172518462724639

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2626,
+    "annotations_size": 2304,
+    "title": "Average number of proteins per term",
+    "value": 2.0638020833333335
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C200/C200_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,168 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+RNA recognition motif domain [IPR000504]	0.4705655873806846	2.81169065647805	0.0049281874266571	0.9999886081771628	0.0383755837723623	100	Q13595,Q13283,Q9Y6M1,Q9GZT3,Q16629,Q92804,Q01130,Q14011,P08621,Q8WXF1,Q8N684,Q8WXA9,Q96T58,O60506,P18615,Q15020,P98179,P52597,O75494,Q16630,P84103,P62995,P22626,Q9BY77,Q13243,Q01844,Q8IY67,Q13151,Q13247,Q86U42,Q07955,Q8IXT5,Q13148,P09651,Q15427,Q13242,P51991,P31943,P35637,Q05519,Q9UKM9	41
+Immunoglobulin-like domain [IPR007110]	0.90484060291292	2.611408949721765	0.0090169995198425	0.999999999135957	0.048882745632276	8	P35613,P01889,P55899,P78310,P10321	5
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.1183203702897548	2	P05067	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8770125687968172	1.987265908003208	0.0468929375248174	1.0	0.1406788125744524	5	O43169,Q8WUJ1	2
+Immunoglobulin C1-set [IPR003597]	0.9157131960335532	1.9739520331222111	0.0483871973780445	1.0	0.1434801837310355	4	P55899,P01889,P10321	3
+MHC class I-like antigen recognition-like [IPR011161]	0.9157131960335532	1.9739520331222111	0.0483871973780445	1.0	0.1434801837310355	4	P55899,P01889,P10321	3
+Immunoglobulin subtype [IPR003599]	0.9132942185683756	1.9646715998310451	0.0494522590413102	1.0	0.1450443520362568	4	P35613	1
+Immunoglobulin subtype 2 [IPR003598]	0.9132942185683756	1.9646715998310451	0.0494522590413102	1.0	0.1450443520362568	4	P35613	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9500762195121965	1.9267511538680968	0.0540106495170542	1.0	0.1506101052791195	2	Q9BTY2	1
+Glycoside hydrolase family 18, catalytic domain [IPR001223]	0.9390243902439036	1.881089358605516	0.0599597643160034	1.0	0.1606719521262622	2	Q01459	1
+Chitinase II [IPR011583]	0.9390243902439036	1.881089358605516	0.0599597643160034	1.0	0.1606719521262622	2	Q01459	1
+Saposin B type domain [IPR008139]	0.9302591463414636	1.8447860751540603	0.065068663826852	1.0	0.1678815245879811	2	Q9Y2B0	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.9708490071075128	1.7614161223339555	0.0781679982282281	1.0	0.1887830900606265	3	Q06210	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6690662511854628	1.693876737813338	0.0902887081603216	1.0	0.208887756385507	9	P62942,Q9Y680	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8936737804878079	1.692508574744941	0.0905490465804295	1.0	0.208887756385507	2	P98179	1
+PI31 proteasome regulator,  N-terminal [IPR021625]	0.8772865853658567	1.6239742989598225	0.1043812938561967	1.0	0.2332633375797064	2	Q92530	1
+SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]	0.9196016484796812	1.5698211725894489	0.1164567204305875	1.0	0.2505547336604686	3	Q08J23	1
+GNAT domain [IPR000182]	0.8092880421433515	1.5591497089922035	0.1189609506615732	1.0	0.2537405094173853	4	Q86UY6	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.9153640869233756	1.5539088383141242	0.1202061632016291	1.0	0.2552580645313857	3	P01889,P10321	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.9153640869233756	1.5539088383141242	0.1202061632016291	1.0	0.2552580645313857	3	P01889,P10321	2
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.850990853658539	1.5137129999733456	0.1300986463522679	1.0	0.2636811458900456	2	Q7Z4V5	1
+START domain [IPR002913]	0.9039484893870766	1.5110037740340627	0.1307874893239526	1.0	0.2640733034739975	3	Q9NQZ5	1
+Cadherin prodomain [IPR014868]	0.834984756097565	1.446498111007828	0.1480375414586343	1.0	0.2878299540259017	2	Q14574	1
+Cadherin, cytoplasmic domain [IPR000233]	0.834984756097565	1.446498111007828	0.1480375414586343	1.0	0.2878299540259017	2	Q14574	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8825772016774738	1.4305658127176943	0.1525546913621767	1.0	0.2942649898454889	3	Q15629,Q96G23	2
+SGNH hydrolase-type esterase domain [IPR013830]	0.8300304878048821	1.4256887897068191	0.1539581938344587	1.0	0.2960932208636001	2	P68402	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.77135483789595	1.4088154570209426	0.1588897433869163	1.0	0.3025470816226902	4	O60884,Q96EY1	2
+Zinc finger, RING-type [IPR001841]	0.4963689767924323	1.3973108860630534	0.1623201036484554	1.0	0.3049048292636546	21	Q99496,Q14527,P22681,P19474	4
+FAD dependent oxidoreductase [IPR006076]	0.8535543213880217	1.3212363610882585	0.1864225658186877	1.0	0.3316738159430553	3	Q96CU9	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6994939252319072	1.3133177075303244	0.1890759141449194	1.0	0.3333059726012963	6	Q9BVA1,Q13885,P68371	3
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6994939252319072	1.3133177075303244	0.1890759141449194	1.0	0.3333059726012963	6	Q9BVA1,Q13885,P68371	3
+2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]	0.8025914634146389	1.3105049502640045	0.1900250706800175	1.0	0.3334484103935722	2	P21912	1
+SKP1 component, POZ domain [IPR016073]	0.7976371951219573	1.2897369467233804	0.1971420068764662	1.0	0.3411993629727298	2	P63208	1
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.8383530308806721	1.2640144559261497	0.20622483839284	1.0	0.352762235076435	3	Q09028,Q9BQ67	2
+Cadherin-like [IPR002126]	0.8353030880670989	1.2525427626530663	0.2103721564031211	1.0	0.3553500354492603	3	Q14126,Q14574	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7873475609756163	1.246652565654222	0.2125249185592037	1.0	0.3576752464283458	2	Q32P28	1
+BTB/POZ domain [IPR000210]	0.8197275627401255	1.1940304433811753	0.2324660596884724	1.0	0.3781653518430395	3	Q08380	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.7163189617401212	1.1899396194540857	0.2340701249288397	1.0	0.3797870196028498	4	P07196	1
+Tudor domain [IPR002999]	0.6571479346585909	1.1397054622945553	0.2544090307243243	1.0	0.4022672697776307	6	Q14739	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.7034004957733637	1.1386568922443985	0.2548462891754699	1.0	0.4022672697776307	4	Q01658	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.8032786885246015	1.1324168281219105	0.2574592332797354	1.0	0.4039277936187902	3	O60884,Q96EY1	2
+RNA recognition motif domain, eukaryote [IPR003954]	0.4934014958120283	1.0594885076660656	0.2893773603577847	1.0	0.4354836304796446	12	Q01130	1
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.5906376410864266	1.036871379819975	0.2997958037811954	1.0	0.4427923051178835	7	P09234	1
+HDGF-related, PWWP domain [IPR035496]	0.7714506361334148	1.0140181201333172	0.3105741060485303	1.0	0.4502941638429766	3	Q7Z4V5	1
+TATA box binding protein associated factor (TAF) [IPR004823]	0.7237042682926882	0.983070614547482	0.3255726856660996	1.0	0.4656235057571034	2	P62805	1
+Chromo domain subgroup [IPR017984]	0.7601982462828927	0.972519092254771	0.3307923714143925	1.0	0.469880162600962	3	Q13185,P83916	2
+Chromo shadow domain [IPR008251]	0.7601982462828927	0.972519092254771	0.3307923714143925	1.0	0.469880162600962	3	Q13185,P83916	2
+Zinc finger, CHHC-type [IPR012996]	0.7582920320244042	0.9655118713705564	0.3342884928500695	1.0	0.4736781596104307	3	P52597,P31943	2
+Pseudouridine synthase II, N-terminal [IPR002501]	0.7187500000000059	0.9628831933809958	0.3356061446864637	1.0	0.4752529547373156	2	Q8WWH5	1
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.4819925140859032	2	Q6DKI1	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.4819925140859032	2	Q6DKI1	1
+Ribosomal protein L30, N-terminal [IPR012988]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.4819925140859032	2	Q6DKI1	1
+CARG-binding factor, N-terminal [IPR012956]	0.7130335365853714	0.9396733235934334	0.3473851526463734	1.0	0.4836105085783953	2	Q99729	1
+Domain of unknown function DUF1747 [IPR013719]	0.7031250000000059	0.8996737357087753	0.3682939044157716	1.0	0.5018031672229082	2	Q08945	1
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.5974960666818028	0.8971267613583358	0.3696512801349523	1.0	0.5030576192740284	6	P09234	1
+60S ribosomal protein L10P, insertion domain [IPR040637]	0.6977896341463476	0.8782676127960407	0.3797985073633145	1.0	0.5114294336441126	2	Q9UKD2	1
+K Homology domain, type 1 [IPR004088]	0.4076100849595576	0.8483001658557905	0.3962708252573903	1.0	0.5274569856709587	22	Q9Y2W6,Q9Y6M1,O75179	3
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.6230680333189335	0.824543379012734	0.4096308783727047	1.0	0.5379045128802897	4	Q92688	1
+Chromo domain [IPR023780]	0.5883238360417649	0.8201769587777272	0.4121152351196975	1.0	0.5394963077930586	5	Q14839,Q13185,P83916	3
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.6802591463414702	0.8086732878578697	0.4187030969874916	1.0	0.5447159432293511	2	Q9UJ83	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.6802591463414702	0.8086732878578697	0.4187030969874916	1.0	0.5447159432293511	2	Q9UJ83	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.6802591463414702	0.8086732878578697	0.4187030969874916	1.0	0.5447159432293511	2	Q9UJ83	1
+Thioredoxin domain [IPR013766]	0.4004097312102678	0.8022485782619874	0.42240918107295	1.0	0.547681909505952	22	O95881	1
+Sterile alpha motif domain [IPR001660]	0.5798952184257413	0.7869617706773906	0.4313042455849483	1.0	0.553298987654633	5	Q15375	1
+Domain of unknown function DUF4217 [IPR025313]	0.6714939024390315	0.7743542958484497	0.4387213033924546	1.0	0.5584607088487378	2	Q13206	1
+K Homology domain [IPR004087]	0.3959392370074238	0.7738083641968317	0.4390441255182347	1.0	0.5585630398641704	22	Q9Y2W6,Q9Y6M1,O75179	3
+F-box domain [IPR001810]	0.6062996576618217	0.7608996236624435	0.4467170233612494	1.0	0.5645836652903559	4	Q8NEZ5,Q9Y3I1	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.6653963414634221	0.7506906264711172	0.4528388655280053	1.0	0.5686401551737272	2	O60506	1
+Histone H2A, C-terminal domain [IPR032454]	0.6944135815072903	0.7360270581298131	0.4617142311212459	1.0	0.5740904417179441	3	P16104	1
+Histone H2A/H2B/H3 [IPR007125]	0.6944135815072903	0.7360270581298131	0.4617142311212459	1.0	0.5740904417179441	3	P16104	1
+Glycoside hydrolase family 31, N-terminal domain [IPR025887]	0.6600609756097637	0.7301364452469492	0.4653067859407136	1.0	0.5773111657551988	2	P10253	1
+Glutaredoxin [IPR002109]	0.5854938146930635	0.683428041226898	0.4943364059998578	1.0	0.5969345279998284	4	P35754	1
+Zinc finger, CXXC-type [IPR002857]	0.6451981707317154	0.6736905409342099	0.5005080768353634	1.0	0.602807427615618	2	Q03164	1
+Homeobox domain [IPR001356]	0.6749971803353096	0.6690580946370079	0.503458420043839	1.0	0.603363817118874	3	Q96G23	1
+EF-hand domain [IPR002048]	0.3199254422523261	0.6494456876896585	0.5160503412150295	1.0	0.6160518063002217	44	O43852,Q14257,Q9Y680,Q96AY3,Q03001,Q02818	6
+CRAL-TRIO lipid binding domain [IPR001251]	0.6246189024390331	0.5977724835661216	0.549991753313781	1.0	0.6457834324274534	2	Q8NHP6	1
+Reticulon [IPR003388]	0.623856707317082	0.5950160845830256	0.551832719405948	1.0	0.6470343946622413	2	Q9NQC3	1
+High mobility group box domain [IPR009071]	0.3968115153951775	0.554501558998107	0.5792356390239635	1.0	0.673339511761459	11	P09429,P26583,O75717	3
+CS domain [IPR007052]	0.4747586518187084	0.5534992942320577	0.5799215637317681	1.0	0.6737969151981813	7	Q9P035	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6074695121951312	0.5368136143603617	0.5913963665650785	1.0	0.6844564350706968	2	Q96AE4	1
+Zinc finger, RanBP2-type [IPR001876]	0.4311670500368513	0.5096972439955679	0.6102635841069031	1.0	0.700920886232455	8	Q92804,Q01844	2
+mRNA splicing factor Cwf21 domain [IPR013170]	0.5990853658536681	0.5078724142175302	0.6115428216790892	1.0	0.7020401899096271	2	Q9UQ35	1
+Spt5 C-terminal domain [IPR024945]	0.5983231707317169	0.5052713014563808	0.6133682967258156	1.0	0.7034348211330409	2	Q9UQ35	1
+Chromo/chromo shadow domain [IPR000953]	0.4559579679575551	0.4817685761482048	0.6299703546240845	1.0	0.719252575348806	7	Q14839,Q13185,P83916	3
+Intermediate filament, rod domain [IPR039008]	0.422241028184383	0.4737483526663787	0.6356793684048454	1.0	0.7225482312801005	8	P07196,P48681	2
+PITH domain [IPR010400]	0.5796493902439126	0.4432056389367345	0.6576170005554338	1.0	0.7409044348556085	2	Q9GZP4	1
+Ubiquitin-associated domain [IPR015940]	0.3818457900882514	0.4247061532274968	0.6710508976325922	1.0	0.7553010591819699	10	Q13501	1
+Zinc finger, C3HC4 RING-type [IPR018957]	0.5979267471166123	0.4238131138473205	0.671702113499755	1.0	0.7556648776872243	3	Q9H000	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.4801493356427748	0.4213765972178	0.6734801055157775	1.0	0.756925933223586	5	Q9HD20	1
+Bms1/Tsr1-type G domain [IPR030387]	0.5705030487804985	0.4140466858056418	0.6788399165612851	1.0	0.7610935122906086	2	Q14692	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.5705030487804985	0.4140466858056418	0.6788399165612851	1.0	0.7610935122906086	2	Q14692	1
+AARP2CN [IPR012948]	0.5705030487804985	0.4140466858056418	0.6788399165612851	1.0	0.7610935122906086	2	Q14692	1
+THUMP domain [IPR004114]	0.567073170731718	0.4033363410339877	0.6867008107543344	1.0	0.7680381883388284	2	Q9NXG2	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.5636432926829377	0.3927521764164778	0.6945025296713045	1.0	0.775258637772619	2	O15344	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.5560213414634259	0.3696958696715728	0.7116091096311401	1.0	0.7901433198024804	2	P24534	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.5560213414634259	0.3696958696715728	0.7116091096311401	1.0	0.7901433198024804	2	P24534	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.5552591463414746	0.3674261954299853	0.7133011348397835	1.0	0.7916405658337482	2	P34897	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.460506891436713	0.3583840959357511	0.7200558919204996	1.0	0.7976432547841416	5	Q9H4A4,P55786	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.460506891436713	0.3583840959357511	0.7200558919204996	1.0	0.7976432547841416	5	Q9H4A4,P55786	2
+CAP Gly-rich domain [IPR000938]	0.4863933609337776	0.3509536685333635	0.7256231073675665	1.0	0.8033808935006599	4	Q99426	1
+Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]	0.4698703279938995	0.3039278913279895	0.761182828093498	1.0	0.8371194443567634	4	Q05639,Q9Y450,P15170	3
+BRCT domain [IPR001357]	0.4315858864331601	0.2978676606239006	0.7658041712492014	1.0	0.8397966732785149	6	Q9NYB0	1
+DnaJ domain [IPR001623]	0.3261955641910208	0.2813387930224966	0.7784505588341453	1.0	0.8492187914554312	14	O60884,Q8IXB1,Q96EY1	3
+SGS domain [IPR007699]	0.522865853658549	0.2774210801628991	0.7814567969827417	1.0	0.8516917976576334	2	Q9Y2Z0	1
+Peptidase M16, C-terminal [IPR007863]	0.3914786685083506	0.2632083536870514	0.7923899924450752	1.0	0.8603518108357462	7	O43847	1
+Peptidase M16, N-terminal [IPR011765]	0.3914786685083506	0.2632083536870514	0.7923899924450752	1.0	0.8603518108357462	7	O43847	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.5095274390244031	0.24426821102551	0.8070231017930538	1.0	0.8725392897847002	2	P18031	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3541191607297131	0.2314814527508517	0.8169407927537355	1.0	0.88037024626034	8	O00303,P51665,O95630	3
+Calponin homology domain [IPR001715]	0.2997581172927493	0.2208552825397275	0.8252051169766204	1.0	0.8855484813759354	20	Q03001,Q15555,Q99439	3
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.3749971099120296	0.2160692817274995	0.8289337437676605	1.0	0.8887218918756118	7	P25788,P60900,P28066	3
+B-box, C-terminal [IPR003649]	0.5135341212352188	0.2117407074807605	0.8323093280956235	1.0	0.8915112468304587	3	Q9UPN9,O15344	2
+ERAP1-like C-terminal domain [IPR024571]	0.5116035273869198	0.2077755305696967	0.8354042394342771	1.0	0.8944104868292632	3	P55786	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.49161585365855	0.2035842017799736	0.8386784397469074	1.0	0.8960943361466425	2	P82675	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.49161585365855	0.2035842017799736	0.8386784397469074	1.0	0.8960943361466425	2	P82675	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.4805640243902578	0.1807391143624696	0.8565723555340081	1.0	0.9115567578327952	2	P55011	1
+SLC12A transporter, C-terminal [IPR018491]	0.4805640243902578	0.1807391143624696	0.8565723555340081	1.0	0.9115567578327952	2	P55011	1
+RNA-binding S4 domain [IPR002942]	0.4763719512195251	0.1725309361295718	0.8630201424900457	1.0	0.915890561168616	2	P46781	1
+LEM domain [IPR003887]	0.3824677803144369	0.1700608859264277	0.8649622538897714	1.0	0.917529020700752	6	P50402	1
+Thioredoxin-like fold [IPR012336]	0.4622713414634234	0.1467754767915968	0.8833092417068156	1.0	0.9297142498366848	2	Q8NBF2	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4020510599725139	0.146086067555505	0.883853444899859	1.0	0.9298622543603996	4	O00303,P51665	2
+OCRE domain [IPR041591]	0.4451219512195256	0.11928526749628	0.905049354994372	1.0	0.9486959571915526	2	P52756	1
+Legume-like lectin [IPR005052]	0.4420731707317227	0.1148329796827964	0.9085775079535068	1.0	0.9506642045072116	2	P49257	1
+GINS subunit, domain A [IPR021151]	0.4367378048780641	0.1073522056392128	0.914509569684788	1.0	0.9547032390365888	2	Q9BRT9	1
+MPN domain [IPR037518]	0.2829380383903247	0.0989239419870161	0.9211986591848572	1.0	0.96125077480159	10	O00303,P51665,O95630	3
+Aminopeptidase P, N-terminal [IPR007865]	0.428734756097573	0.0968619812562286	0.9228360013515192	1.0	0.9619770394566012	2	Q9NQH7	1
+DDT domain [IPR018501]	0.4437883580081843	0.0964700783492696	0.923147237082702	1.0	0.9619770394566012	3	Q12830	1
+WHIM2 domain [IPR028941]	0.4437883580081843	0.0964700783492696	0.923147237082702	1.0	0.9619770394566012	3	Q12830	1
+Dbl homology (DH) domain [IPR000219]	0.4384292794510062	0.0899836717509615	0.92830019024007	1.0	0.9663548458763312	3	O75962,Q12802	2
+TGS [IPR004095]	0.3370229007633629	0.0831830902347754	0.9337059581742946	1.0	0.9690353728079166	6	Q9BW92,P26639,Q9NYK5,Q9Y295,Q9NTK5	5
+Rhodanese-like domain [IPR001763]	0.354916830856625	0.0734171227577682	0.9414741923743496	1.0	0.9762180644601718	4	P25325	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.4016768292683004	0.0675872729829052	0.9461141869200276	1.0	0.9781458024066172	2	P32322	1
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.4016768292683004	0.0675872729829052	0.9461141869200276	1.0	0.9781458024066172	2	P32322	1
+Brix domain [IPR007109]	0.3493516399694906	0.0668423100624816	0.946707240148398	1.0	0.9781458024066172	4	Q8TDN6,Q96G21,Q9H7B2	3
+Arf GTPase activating protein [IPR001164]	0.4005335365853744	0.0665495609980591	0.946940301161138	1.0	0.9781458024066172	2	Q8N6T3	1
+Armadillo repeat-containing domain [IPR006911]	0.4001524390244035	0.0662070652120867	0.9472129718928112	1.0	0.9781458024066172	2	Q9UH62	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.3959603658536714	0.062550763875317	0.950124237324898	1.0	0.9781458024066172	2	P62495	1
+eRF1 domain 2 [IPR005141]	0.3959603658536714	0.062550763875317	0.950124237324898	1.0	0.9781458024066172	2	P62495	1
+eRF1 domain 3 [IPR005142]	0.3959603658536714	0.062550763875317	0.950124237324898	1.0	0.9781458024066172	2	P62495	1
+WSTF/Acf1/Cbp146 [IPR013136]	0.3932926829268372	0.0603285000270218	0.9518940035399156	1.0	0.97952826447341	2	Q9NRL2	1
+PWI domain [IPR002483]	0.3231590995803068	0.0576441292990988	0.9540320979937608	1.0	0.9798834877012614	5	Q5T8P6,Q9P2N5,Q8IYB3,P49756	4
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.3879573170731804	0.0561211721295468	0.9552452775967816	1.0	0.9798834877012614	2	P00387	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.3879573170731804	0.0561211721295468	0.9552452775967816	1.0	0.9798834877012614	2	P00387	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.3879573170731804	0.0561211721295468	0.9552452775967816	1.0	0.9798834877012614	2	P00387	1
+Threonine-tRNA ligase catalytic core domain [IPR033728]	0.3856707317073256	0.0544125185039592	0.9566065053073828	1.0	0.9798834877012614	2	Q9BW92	1
+Phosphoribosyltransferase domain [IPR000836]	0.3160305343511465	0.0537001614927998	0.9571740541365484	1.0	0.9798834877012614	6	Q06203,P00492,P60891,O60256,P07741	5
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.3997372728737952	0.0524338191161175	0.9581830274120252	1.0	0.9798834877012614	3	Q06787	1
+Agenet-like domain [IPR008395]	0.3997372728737952	0.0524338191161175	0.9581830274120252	1.0	0.9798834877012614	3	Q06787	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.3997372728737952	0.0524338191161175	0.9581830274120252	1.0	0.9798834877012614	3	Q06787	1
+Fxr1, tudor domain [IPR041560]	0.3997372728737952	0.0524338191161175	0.9581830274120252	1.0	0.9798834877012614	3	Q06787	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.380335365853667	0.0506390964656908	0.959613108300396	1.0	0.9798834877012614	2	P51114	1
+WHIM1 domain [IPR028942]	0.3934426229508179	0.0477593011334771	0.9619080725100724	1.0	0.9806354863111534	3	Q96T23,Q9NRL2	2
+NOT2/NOT3/NOT5, C-terminal [IPR007282]	0.3677591463414738	0.0428639387108306	0.9658099950554716	1.0	0.9820062791737896	2	O75175	1
+NOPS [IPR012975]	0.3781214482705287	0.0378760066994223	0.9697865431989748	1.0	0.9843119804098844	3	Q8WXF1	1
+Aminoacyl-tRNA synthetase, class II [IPR006195]	0.2367112810707471	0.0289065333118011	0.9769391349713016	1.0	0.9898275140606329	11	O43776,Q15046,Q6PI48,P07814,Q9BW92,P14868,Q9Y285,P26639,P41250,P49591	10
+Replication factor C, C-terminal [IPR013748]	0.3568433091879496	0.0273093841123681	0.9782129722218498	1.0	0.9902625030543056	3	P35250,P35249	2
+BAT2, N-terminal [IPR009738]	0.3182164634146445	0.0245313174213537	0.9804288035368528	1.0	0.9916189479143585	2	Q9Y520	1
+Tim10-like [IPR004217]	0.3435168579554492	0.0223054440931758	0.9822043062054392	1.0	0.9925505040940172	3	Q9Y5J9	1
+R3H domain [IPR001374]	0.3232939382386571	0.0166651807250324	0.9867037250578812	1.0	0.995547498646569	3	O95453,Q9H6S0	2
+Small-subunit processome, Utp12 [IPR007148]	0.2920320243995435	0.0114583545578177	0.9908577558600148	1.0	0.995547498646569	3	Q9UNX4,Q15061	2
+Nop domain [IPR002687]	0.2821197102554353	0.0104545333097494	0.9916586412299808	1.0	0.995547498646569	3	Q8WWY3,Q9Y2X3	2
+NOSIC [IPR012976]	0.2821197102554353	0.0104545333097494	0.9916586412299808	1.0	0.995547498646569	3	Q8WWY3,Q9Y2X3	2
+Cullin, N-terminal [IPR001373]	0.2590485759152861	0.0040972371523185	0.9967308868808452	1.0	0.9996142519988478	6	Q86Y37	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:006423aa827800f8ae7c6e7392bc9ae0f59097d18ffca76d96dd53fc184c3b53
+size 424447

interpro_family/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2626,
+    "annotations_size": 2091,
+    "title": "Average number of proteins per term",
+    "value": 1.272596843615495
+}

interpro_family/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C200/C200_val_log2fc"}

interpro_family/result.tsv

@@ -0,0 +1,72 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ergosterol biosynthesis ERG4/ERG24 [IPR001171]	0.994283536585366	2.1080234271084324	0.0350289630629774	1.0	0.0893238558105924	2	Q9UBM7	1
+Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]	0.9931402439024392	2.10336489802145	0.0354338844046187	1.0	0.0899177819054098	2	Q8IXU6	1
+Amyloidogenic glycoprotein [IPR008155]	0.9908536585365856	2.0940429417101556	0.0362561551321904	1.0	0.0914494817628592	2	P05067	1
+Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]	0.977134146341464	2.0379761449544977	0.0415523186055004	1.0	0.099983772386768	2	Q99595	1
+Alpha-L-fucosidase, metazoa-type [IPR016286]	0.9500762195121965	1.9267511538680968	0.0540106495170542	1.0	0.1178725211196624	2	Q9BTY2	1
+Glycoside hydrolase, family 29 [IPR000933]	0.9500762195121965	1.9267511538680968	0.0540106495170542	1.0	0.1178725211196624	2	Q9BTY2	1
+Pyridoxal phosphate-dependent decarboxylase [IPR002129]	0.914253048780488	1.7783045085169753	0.075353856288554	1.0	0.1517966411361913	2	Q6P996	1
+Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]	0.9070121951219524	1.748155323152191	0.0804371354227746	1.0	0.1591239831305788	2	Q92688	1
+Nucleosome assembly protein (NAP) [IPR002164]	0.9447197865040016	1.6639440695617822	0.0961236070382507	1.0	0.1775569455097016	3	Q99733,P55209	2
+Calponin/LIMCH1 [IPR001997]	0.8852896341463443	1.6574655647029088	0.0974253853071271	1.0	0.1786986672607043	2	Q99439	1
+CPSF6/7 family [IPR034772]	0.8769054878048785	1.6223785591677573	0.1047223171168534	1.0	0.1877996270080107	2	Q8N684	1
+RNA (C5-cytosine) methyltransferase [IPR023267]	0.9196016484796812	1.5698211725894489	0.1164567204305875	1.0	0.2009965187889494	3	Q08J23	1
+Twinfilin [IPR028458]	0.8422256097560986	1.4769095126395164	0.1396998946631353	1.0	0.2282128747973562	2	Q6IBS0	1
+Peptidase A22B, signal peptide peptidase [IPR007369]	0.8387957317073219	1.4625047119809187	0.1436029540692525	1.0	0.2327703697355092	2	Q8TCT8	1
+Presenilin/signal peptide peptidase [IPR006639]	0.8387957317073219	1.4625047119809187	0.1436029540692525	1.0	0.2327703697355092	2	Q8TCT8	1
+Nucleobindin [IPR040250]	0.8376524390243929	1.4577028392313127	0.1449224690299444	1.0	0.2341050484521478	2	Q02818	1
+Beta tubulin [IPR002453]	0.6994939252319072	1.3133177075303244	0.1890759141449194	1.0	0.2838174705506292	6	Q9BVA1,Q13885,P68371	3
+Tubulin [IPR000217]	0.6994939252319072	1.3133177075303244	0.1890759141449194	1.0	0.2838174705506292	6	Q9BVA1,Q13885,P68371	3
+DnaJ homolog subfamily A member 1/2-like [IPR044713]	0.8029725609756142	1.3121030224352486	0.1894853763410227	1.0	0.2840243167950383	2	O60884	1
+S-phase kinase-associated protein 1-like [IPR001232]	0.7976371951219573	1.2897369467233804	0.1971420068764662	1.0	0.2924001312210286	2	P63208	1
+Desmosomal cadherin [IPR009122]	0.8353030880670989	1.2525427626530663	0.2103721564031211	1.0	0.3050542156996715	3	Q14126,Q14574	2
+Casein Kinase 2, subunit alpha [IPR045216]	0.7724847560975645	1.1845758949675247	0.2361851723804002	1.0	0.3307904434515916	2	P19784	1
+TAF15/EWS/TLS family [IPR034870]	0.81052230270683	1.1595223053813646	0.2462433499045659	1.0	0.341895647178252	3	Q92804,Q01844	2
+Chaperone DnaJ [IPR012724]	0.8032786885246015	1.1324168281219105	0.2574592332797354	1.0	0.3516311278823819	3	O60884,Q96EY1	2
+Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]	0.7496189024390296	1.0895942334273836	0.275891924389656	1.0	0.3690914996153364	2	P62314	1
+SCAMP [IPR007273]	0.7492378048780532	1.088017988233984	0.276587166490158	1.0	0.3695487317130482	2	O15127	1
+Calreticulin/calnexin [IPR001580]	0.7750667174990514	1.0273998188080582	0.3042322367801966	1.0	0.3929274904925207	3	O14967,P27824	2
+Heterogeneous nuclear ribonucleoprotein C [IPR017347]	0.7313262195122001	1.0142489197832418	0.3104639910493145	1.0	0.398514552046726	2	Q9UKM9	1
+Ribosomal protein L7, eukaryotic [IPR005998]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.4288714483641683	2	Q6DKI1	1
+Ribosomal protein L7/L30 [IPR039699]	0.7137957317073227	0.9427625918906052	0.3458023497731142	1.0	0.4288714483641683	2	Q6DKI1	1
+Tumour protein D52 [IPR007327]	0.7122713414634203	0.936585756898286	0.3489716812891923	1.0	0.4316515311084768	2	O43399	1
+KH domain-containing BBP-like [IPR045071]	0.7452935648304535	0.9179282556475868	0.3586564277024506	1.0	0.4395958911640236	3	Q15637	1
+Smooth muscle protein/calponin [IPR003096]	0.7190754131033463	0.8231999445355528	0.4103943004215229	1.0	0.4851751089569079	3	Q99439	1
+RNA-binding protein 26/27 [IPR045137]	0.6794969512195189	0.8056755387377277	0.4204299573906409	1.0	0.492894446063029	2	Q9P2N5	1
+Peptidase S10, serine carboxypeptidase [IPR001563]	0.7028355351196638	0.7655537254328953	0.4439418874469027	1.0	0.511496176094888	3	Q9H3G5	1
+HnRNP R/Q splicing factor [IPR006535]	0.6653963414634221	0.7506906264711172	0.4528388655280053	1.0	0.5191261336727298	2	O60506	1
+Histone H2A [IPR002119]	0.6944135815072903	0.7360270581298131	0.4617142311212459	1.0	0.5252690191917982	3	P16104	1
+Glycoside hydrolase family 31 [IPR000322]	0.6600609756097637	0.7301364452469492	0.4653067859407136	1.0	0.5276336710423168	2	P10253	1
+Ras GTPase-activating protein-binding protein [IPR039539]	0.6291920731707403	0.6143976873723781	0.53895256361434	1.0	0.5821021748541244	2	Q13283	1
+Mitochondrial carrier protein [IPR002067]	0.4046921420045938	0.5915154619850932	0.5541750982555971	1.0	0.5930297494638964	11	P12235	1
+P-type ATPase [IPR001757]	0.4801493356427748	0.4213765972178	0.6734801055157775	1.0	0.7090870597348896	5	Q9HD20	1
+Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]	0.5705030487804985	0.4140466858056418	0.6788399165612851	1.0	0.7140111999646113	2	Q14692	1
+Serine hydroxymethyltransferase [IPR001085]	0.5552591463414746	0.3674261954299853	0.7133011348397835	1.0	0.7476253999749309	2	P34897	1
+Ribosomal protein L24e-related [IPR000988]	0.5525914634146454	0.3595348118074588	0.7191950402796055	1.0	0.7531049320470337	2	Q9UHA3	1
+Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]	0.460506891436713	0.3583840959357511	0.7200558919204996	1.0	0.7535720070098921	5	Q9H4A4,P55786	2
+Protein disulphide isomerase [IPR005792]	0.5242950574875307	0.2346256765547907	0.8144992787693206	1.0	0.8439053247397483	3	P07237	1
+HAD-superfamily hydrolase, subfamily IIA [IPR006357]	0.5206031472218188	0.226625484342248	0.8207149741810973	1.0	0.8491415195510511	3	Q9BXW7	1
+Proteasome alpha-type subunit [IPR023332]	0.3749971099120296	0.2160692817274995	0.8289337437676605	1.0	0.8555283604235825	7	P25788,P60900,P28066	3
+Aminopeptidase N-type [IPR034016]	0.5116035273869198	0.2077755305696967	0.8354042394342771	1.0	0.8617810876453249	3	P55786	1
+Isocitrate dehydrogenase NADP-dependent [IPR004790]	0.4927591463414767	0.2060466923151342	0.8367544385543302	1.0	0.8623230808364241	2	P48735	1
+Ribosomal protein S5 [IPR000851]	0.49161585365855	0.2035842017799736	0.8386784397469074	1.0	0.8638801071481691	2	P82675	1
+Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]	0.5085779641631649	0.2016483965574122	0.8401916073301479	1.0	0.8650126297032689	3	O76021,Q9BYD6	2
+SLC12A transporter family [IPR004842]	0.4805640243902578	0.1807391143624696	0.8565723555340081	1.0	0.8801438798140594	2	P55011	1
+Mitochondrial carrier UCP-like [IPR002030]	0.4790396341463523	0.1777251340724661	0.8589388453442903	1.0	0.8821420066870879	2	Q9UBX3	1
+Prefoldin alpha-like [IPR004127]	0.4748475609756238	0.1696087313403165	0.8653178554296521	1.0	0.8873857948520857	2	Q99471	1
+Graves disease carrier protein [IPR002167]	0.4626524390244006	0.1474340053918665	0.8827894663667193	1.0	0.9026468333363374	2	Q86VD7	1
+Initiation factor 2B-related [IPR000649]	0.4776972931757467	0.1452877285767288	0.8844837031006298	1.0	0.9039371569811422	3	Q14232,P49770	2
+Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]	0.4447408536585505	0.1187216261738251	0.90549590251339	1.0	0.9241618425720406	2	Q9NX24	1
+Ribosomal protein L3 [IPR000597]	0.4294969512195213	0.0978237284385609	0.9220722651791656	1.0	0.93913936019953	2	P39023	1
+Synaptobrevin [IPR001388]	0.4028201219512334	0.0686404043744771	0.9452758566527646	1.0	0.961367614912904	2	O75396	1
+Pyrroline-5-carboxylate reductase [IPR000304]	0.4016768292683004	0.0675872729829052	0.9461141869200276	1.0	0.9617524379434992	2	P32322	1
+Threonine-tRNA ligase, class IIa [IPR002320]	0.3856707317073256	0.0544125185039592	0.9566065053073828	1.0	0.9710020400959888	2	Q9BW92	1
+Fragile X mental retardation syndrome-related protein [IPR040148]	0.3997372728737952	0.0524338191161175	0.9581830274120252	1.0	0.9721303786116182	3	Q06787	1
+Ribosomal protein L14P [IPR000218]	0.3810975609756205	0.0511601874588622	0.959197876081724	1.0	0.9725141327047404	2	Q6P1L8	1
+Not2/Not3/Not5 [IPR040168]	0.3677591463414738	0.0428639387108306	0.9658099950554716	1.0	0.9770240443449402	2	O75175	1
+Ribosomal protein L10P [IPR001790]	0.3743804803659886	0.0357657850331468	0.9714691151903452	1.0	0.9817988979521564	3	P05388,Q9UKD2	2
+ClpA/B family [IPR001270]	0.3307926829268393	0.0276604794710934	0.9779329444466662	1.0	0.9878540033033716	2	Q9H078	1
+ADF/Cofilin [IPR017904]	0.3533925171482238	0.0259039612869357	0.979333940458077	1.0	0.9884159395827606	3	P60981	1
+Protein PRRC2 [IPR033184]	0.3182164634146445	0.0245313174213537	0.9804288035368528	1.0	0.988872592043468	2	Q9Y520	1
+Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]	0.3435168579554492	0.0223054440931758	0.9822043062054392	1.0	0.9897779297713608	3	Q9Y5J9	1
+Small GTPase superfamily, ARF/SAR type [IPR006689]	0.2723477769805961	0.0121558090956243	0.990301306451588	1.0	0.9960173313084514	6	Q8N8L6	1