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Protein localization 0.6280618025837502 4.134001497483836 3.5650114864616e-05 0.0483806758306958 0.043497642270219 73 P06576,P46379,Q8N4H5,O43681,Q9Y3D6,Q9NS69,O43615,P56589,Q10713,P40855,Q5T8D3,O60830,O14925,Q5JRX3,P09601,P28288,P50402,Q9Y5J9,P08574,Q9BY49,Q9Y512,Q13505,P05067,P21796,P39210,P51648,O96008,P14735,Q7L5D6,Q9Y5J6,Q9NR77,Q8TB36,Q15388,Q9NX63,O75431,P12236,Q9UJS0,O75746,O43808,O00116,O15254,O15228,P12235,Q3ZCQ8,O75381 45
Sphingolipid metabolism 0.826352388193725 4.003010438037494 6.254154172569137e-05 0.0833210756524068 0.043497642270219 28 P16278,P07602,Q16739,O43681,P17900,Q9NZJ7,Q16880,P04062,Q13510,Q96G23,O15269,P51648,P10619,O95470,Q06136 15
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.6052040129634736 3.8730409396761 0.0001074857637113 0.1388794159003227 0.0498375657741559 63 O14949,Q9P0J0,Q9BQ95,P06576,P20674,P56385,Q9UDW1,O43819,P22695,P03886,O43676,O95139,O14548,P24539,P08574,P00403,Q99643,Q86Y39,Q8N8Q8,P13073,O95168,O95299,O96000,O75964,Q9Y6M9,P21912,O75880,P51970 28
Glycosphingolipid metabolism 0.8413337838220211 3.5225479388484775 0.0004274197333293 0.4482542543502703 0.0823038706096804 17 P16278,P07602,Q16739,P17900,O43681,Q9NZJ7,P06280,P04062,Q16880,Q13510,P10619 11
Mitochondrial protein import 0.717397465551409 3.435396008607837 0.0005916885018668 0.5610116015408413 0.0823038706096804 33 P06576,Q8N4H5,O43615,Q9NS69,Q10713,O60830,O14925,Q5JRX3,Q9Y5J9,Q9Y512,Q13505,P21796,O96008,Q9Y5J6,Q15388,Q9NX63,O75431,P12236,Q9UJS0,O75746,P12235 21
Cristae formation 0.7713152229893352 3.336604913900564 0.0008480841293909 0.6927782695487266 0.0907450018448338 20 P06576,Q5XKP0,P24539,Q9Y512,Q13505,Q16891,Q9BUR5,Q6UXV4,O75964,Q9NX63,O75431 11
Respiratory electron transport 0.5930864343071054 3.2442085807930066 0.0011777746614829 0.8058744331181675 0.1084339015584374 54 O14949,Q9P0J0,Q9BQ95,P20674,Q9UDW1,O43819,P22695,P03886,O43676,O95139,O14548,P08574,P00403,Q99643,Q86Y39,Q8N8Q8,P13073,O95168,O95299,O96000,Q9Y6M9,P21912,O75880,P51970 24
Glycerophospholipid biosynthesis 0.6866868007797177 3.22784561141403 0.0012472627066391 0.8237805683771169 0.1084339015584374 33 O95674,Q9UG56,Q8N2A8,P35790,Q9HCL2,Q96N66,Q9NPH0,Q8NAN2,Q9NUQ2,Q8IV08,Q53H12,P40939,Q9BVG9,Q92604,Q8NF37 15
Ion channel transport 0.6649176467985758 3.034380474874664 0.0024103024262827 0.9651526340380856 0.1862628152755136 31 Q04656,Q96PU5,P98194,Q93050,Q9C0H2,P23634,Q15904,Q9HD20,Q9NW15,P20020,Q9Y487,Q4KMQ2,P27105,P05023,P51790,P51798,P35670,P16615 18
Glycosaminoglycan metabolism 0.7436190015811448 2.9211174966304543 0.0034877826308521 0.9922494065311545 0.2205229836143332 16 P16278,P34059,Q8N6G5,Q8NCH0,Q8TB61,P54802,Q96L58,Q7LGA3,O43252,P06865,O75330,O94923 12
Sphingolipid de novo biosynthesis 0.8162500265502037 2.8360364487787257 0.0045677232769563 0.9982848562746272 0.2762479599237493 11 Q06136,O95470,Q96G23,P51648 4
Slc mediated transmembrane transport 0.6908792526261515 2.7883279820189717 0.0052980875460379 0.9993821293982206 0.2947855910615544 19 O00400,P12236,Q70HW3,P05141,Q8TB61,Q9UBX3,P04920,Q15043,P30825,P12235,P35613 11
Mitophagy 0.7507059252490635 2.691488910385353 0.0071133863215644 0.9999513121304868 0.2974492551888003 13 Q8IWA4,Q8N4H5,Q15388,Q9NS69,P21796,O96008 6
Mitochondrial calcium ion transport 0.7023831676954682 2.6831268815634997 0.0072937312468108 0.999962183333194 0.2974492551888003 16 Q8NE86,Q9UJZ1,Q99623,Q9Y277,P45880,Q9Y4W6,Q8WWC4,Q9BPX6,P21796,Q10713,Q96TA2,P35232,O95202 13
The citric acid tca cycle and respiratory electron transport 0.5053880940285803 2.670621347577161 0.0075710999986131 0.9999743628891778 0.2974492551888003 97 O14949,Q9P0J0,Q9BQ95,P06576,P20674,Q9H9P8,P56385,Q9UDW1,P09622,O43819,P03886,P22695,O43676,O95139,O14548,P24539,P08574,P00403,Q99643,P21796,Q86Y39,Q13423,P48163,Q8N8Q8,P13073,O95168,O95299,O96000,O75964,Q9Y6M9,P21912,O75880,Q9P0J1,P51970,P35613 35
Pink1 prkn mediated mitophagy 0.8485525693346558 2.639411523603305 0.0083050098387371 0.9999908385564836 0.2974492551888003 8 Q8IWA4,Q8N4H5,Q15388,Q9NS69,P21796,O96008 6
Stimuli sensing channels 0.7876039595556955 2.600365429748465 0.0093124535201265 0.9999977717965848 0.2974492551888003 10 Q96PU5,Q9C0H2,P27105,P51798,P51790 5
Class i peroxisomal membrane protein import 0.7509593964213943 2.5960844318860516 0.0094292891471807 0.9999981089354676 0.2974492551888003 12 P28288,Q9NR77,Q8TB36,O43808,Q9Y3D6,P51648,P56589,P40855,O75381,Q5T8D3 10
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7829335201152491 2.5769151735505575 0.0099686410799388 0.9999991134754368 0.2974492551888003 10 P09601,O43681,P50402,P05067,P51648 5
Metabolism of porphyrins 0.7990328973137114 2.5711484220138394 0.0101361875596388 0.999999299436436 0.2974492551888003 9 P30519,P09601,Q7KZN9 3
Phospholipid metabolism 0.5110883962287827 2.515313415143393 0.0118926608623124 0.9999999407705232 0.2974492551888003 54 O95674,Q9UG56,Q8N2A8,P35790,Q9HCL2,Q96N66,Q9NPH0,Q8NAN2,Q9NUQ2,Q8IV08,Q53H12,Q10713,P48651,P40939,Q9BVG9,Q92604,Q8NF37 17
Ion transport by p type atpases 0.7357841151339829 2.515137612949188 0.011898593022497 0.9999999412630874 0.2974492551888003 12 P98194,P23634,Q9HD20,P20020,P05023,P16615,P35670,Q04656 8
Transport of small molecules 0.5408338117026533 2.450421877323298 0.0142688922582365 0.9999999979202028 0.2974492551888003 157 Q9C0H2,P05141,P20020,P55011,Q4KMQ2,Q8TDW0,P09601,Q9NRK6,P30519,P23634,P45880,Q6PIU2,P21796,Q13616,P35670,O15118,O95202,Q70HW3,Q9Y277,P30825,P49721,P54709,Q93050,Q9UBX3,Q9HD20,Q9UEY8,Q9Y487,O00400,Q8NE86,Q9Y289,P56589,P40855,Q96TA2,Q9UBV2,Q9GZP9,P16615,Q8WTV0,Q96PU5,P28288,O75477,Q8TB61,P27105,P51798,Q99623,P61421,P53985,P36543,Q15043,Q8WWC4,P28070,P51790,O00231,Q9UJZ1,P28072,P07237,O75027,P35613,P61289,Q99797,Q9NW15,Q10713,P05023,P98194,Q04656,P61916,P12236,Q15904,Q9NUT2,Q9NP58,P12235,Q9BU23,P10644,Q9BUN8,Q9UL46,P63218,Q9BPX6,P04920,O94905,P35232 79
Cholesterol biosynthesis 0.6422765360942702 2.4279955757739224 0.0151825284819588 0.9999999994274136 0.2974492551888003 18 Q15392,P37268,Q14534,Q15800,Q16850,Q15125,Q14739 7
Ire1alpha activates chaperones 0.6001452238948847 2.3954256640511566 0.0166010800947085 0.9999999999229008 0.3086528593587077 22 O95070,P02545,P43307,Q9Y5M8,O76024 5
Mitochondrial biogenesis 0.5590461229276255 2.324682499151915 0.0200889437591915 0.9999999999994496 0.3211921927475342 34 P06576,Q5XKP0,P24539,Q9Y512,Q13505,Q16891,Q9BUR5,Q6UXV4,O75964,Q9NX63,O75431 11
Gpcr ligand binding 0.7262895890203749 2.2870175270481403 0.0221948000843628 0.9999999999999724 0.3480522973668806 10 P42892,P07602,Q9NZJ7,P05067 4
Depolymerisation of the nuclear lamina 0.739455699757651 2.273982323859455 0.0229670493232969 0.9999999999999908 0.351067753941825 9 P50402,P02545,P42167 3
Formation of atp by chemiosmotic coupling 0.725915407933181 2.2049374196520213 0.0274584862328892 1.0 0.3708228577664948 9 P06576,O75964,P24539 3
Synthesis of pa 0.677226311792641 2.195084841811769 0.0281575123472039 1.0 0.3733859149473224 12 Q8N2A8,Q9HCL2,Q9NPH0,Q8NAN2,Q8NF37 5
Synthesis of very long chain fatty acyl coas 0.750728458866058 2.172541686880218 0.0298148288581254 1.0 0.3736174678492502 8 Q9NZ01,Q9P035,Q9UKU0 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6020927343466024 2.171994610500565 0.0298560694357403 1.0 0.3736174678492502 18 O43852,Q07065,Q02818,P05067,O43493,O76024 6
Peptide ligand binding receptors 0.7793968361301957 2.1619766066694224 0.03061997939239 1.0 0.3736174678492502 7 P42892,P07602,Q9NZJ7 3
Class a 1 rhodopsin like receptors 0.7793968361301957 2.1619766066694224 0.03061997939239 1.0 0.3736174678492502 7 P42892,P07602,Q9NZJ7 3
Initiation of nuclear envelope ne reformation 0.617436642831936 2.123926479041827 0.0336762918341604 1.0 0.3944180545228778 15 P02545,P20700,P50402,Q14739,P42167 5
Intra golgi traffic 0.6094196339905447 2.1197339764124457 0.0340284859804371 1.0 0.3944180545228778 16 Q16706,O15498,O00461,Q8TBA6,O95249,Q99747 6
Processing of smdt1 0.6764564310744827 2.1042442986323553 0.0353571421537715 1.0 0.3944180545228778 11 Q8NE86,Q9UJZ1,Q99623,Q9Y4W6,Q8WWC4,Q9BPX6,Q10713,Q96TA2,P35232 9
Cytoprotection by hmox1 0.4310509286086924 2.0924563074694107 0.0363977163457911 1.0 0.3944180545228778 62 P09601,O14548,Q8N8Q8,P28072,P61289,P30519,P13073,P00403,O75880,O43819,P49721,O00231 12
N glycan trimming in the er and calnexin calreticulin cycle 0.6031349755871095 2.0802459194730187 0.0375029823746073 1.0 0.3982186907105255 16 O60858,P27824,Q04323,Q9UBV2,Q9GZP9 5
Rhoa gtpase cycle 0.4893477481267835 2.0631091414309246 0.0391022598472303 1.0 0.4073955992128911 47 O14578,O15498,Q96HY6,P28288,Q96CS3,Q8NBN3,P30519,P51572,Q15904,Q8TAA9,P27105,Q86UP2,O75955,O15173,O75962,Q14739,Q5T8D3,P42167 18
Heparan sulfate heparin hs gag metabolism 0.8246268656716397 2.05314572917958 0.0400584460329971 1.0 0.4097154296463162 5 P54802,P16278,Q7LGA3,Q96L58 4
Chondroitin sulfate dermatan sulfate metabolism 0.8173296047674556 2.02160015106976 0.0432176764493217 1.0 0.4233506193028629 5 Q8N6G5,Q8NCH0,P06865 3
Selective autophagy 0.5228625480388506 2.0104695205363208 0.0443815189736502 1.0 0.4257565027058451 32 Q8IWA4,Q8N4H5,Q15388,Q9NS69,P21796,O96008,P08670 7
Complex i biogenesis 0.5252033532558306 1.9873567316592349 0.0468828789519955 1.0 0.4259744564252718 29 Q9P0J0,O95168,O95299,O96000,P51970,Q86Y39,Q9Y6M9,P03886,O43676,O95139 10
Transport of vitamins nucleosides and related molecules 0.7133727457370787 1.9872975245077027 0.046889435842147 1.0 0.4259744564252718 8 P12236,O00400,P05141,Q8TB61,P12235 5
Ras processing 0.8020005809442222 1.954994916714628 0.0505836702611719 1.0 0.4453283881853808 5 O60725 1
Cargo concentration in the er 0.6031828599397369 1.9412536566991103 0.0522275177220312 1.0 0.4512327773375497 14 Q5JRA6,P53634,Q15363,P49755,Q96PC5,O75396 6
P75 ntr receptor mediated signalling 0.6287787006773962 1.9208572035276117 0.0547497124195783 1.0 0.4701040121952686 12 Q9NQC3,Q92542 2
Transport of inorganic cations anions and amino acids oligopeptides 0.6979754120448304 1.9098270107456263 0.0561554902877934 1.0 0.4762944328678089 8 P30825,Q70HW3,P04920,Q9UBX3 4
Keratan sulfate keratin metabolism 0.7513570314428493 1.893961982261514 0.05823005629185 1.0 0.4879398090479726 6 P06865,P16278,P34059,O43505 4
Calnexin calreticulin cycle 0.660967331033293 1.8659255232442895 0.0620517861228462 1.0 0.5065614476086362 9 Q9UBV2,O60858,Q9GZP9 3
Rhog gtpase cycle 0.5007019474081114 1.865309683209572 0.0621380086441636 1.0 0.5065614476086362 34 O15498,P84095,P50402,Q86XL3,O15173,O75962,P42167,Q14739,O95202 9
Er quality control compartment erqc 0.8834466780644119 1.851143239232939 0.06414894896969 1.0 0.5069953864593116 4 Q9UBV2,O60858 2
Pre notch processing in golgi 0.8773244953891745 1.8264070543343345 0.0677889700658869 1.0 0.5177712064625385 4 Q9UBV2,Q15363 2
Post translational modification synthesis of gpi anchored proteins 0.6766680741028989 1.8015684265083929 0.071613332542044 1.0 0.5298624764148047 8 Q96S52,Q5H8A4,Q92643 3
Rac2 gtpase cycle 0.4890747033224204 1.78663487935815 0.0739965204834347 1.0 0.5398486731639432 35 P50402,Q9Y512,Q13505,Q86XL3,O15173,O75962,Q14739,P42167 8
Miro gtpase cycle 0.7623297002688064 1.7805504976932365 0.0749859128232559 1.0 0.5403773169049629 5 Q8IXI1,Q8IWA4 2
Antigen presentation folding assembly and peptide loading of class i mhc 0.5495976872051365 1.7796268195261995 0.0751370540407692 1.0 0.5403773169049629 17 Q03519,Q6P179,Q9NZ08,P51572,Q03518,P10321,P27824 7
Death receptor signalling 0.5320266142330451 1.7541555050338782 0.0794038650539388 1.0 0.5606638390356797 19 Q9NQC3,Q8TCT8,Q92542 3
Cellular response to chemical stress 0.3943720582372 1.7353917166751462 0.0826714462641866 1.0 0.5664826687363727 73 P20674,P09601,O14548,Q9UL46,Q8N8Q8,P61289,P30519,P13073,P28072,P00403,O75880,O43819,Q8TED1,Q13616,P49721,Q04656,O00231 17
Integrin cell surface interactions 0.8512845735861279 1.7206656479930105 0.0853115133606947 1.0 0.578689333052765 4 Q08722 1
Keratan sulfate degradation 0.748378831102545 1.7185247915448678 0.0857009364549745 1.0 0.578689333052765 5 P06865,P16278,P34059 3
Interleukin 4 and interleukin 13 signaling 0.5889348346939228 1.6889820347701576 0.0912228728111916 1.0 0.5880046195866433 12 P08670,Q07820,P09601 3
Tp53 regulates metabolic genes 0.4747924845824806 1.684495131957189 0.0920860194695825 1.0 0.5880046195866433 36 Q15382,P20674,O14548,Q8N8Q8,P04637,P13073,P00403,O75880,O43819,P31751 10
G alpha s signalling events 0.678792279417878 1.6767034206011873 0.0936004914049732 1.0 0.5880046195866433 7 P63096,P63218,P04899 3
Transport to the golgi and subsequent modification 0.3914922104714825 1.6626608645055925 0.0963803402341874 1.0 0.5880046195866433 76 Q9Y6Y8,O15498,Q15363,Q96PC5,Q13509,Q9Y296,Q9Y3B3,P53634,P24390,Q9HCU5,Q14789,Q13561,O95249,O75935,Q5JRA6,P62820,Q16706,Q9BVK6,P49755,O75396 20
Diseases associated with n glycosylation of proteins 0.7324349099592614 1.647232253919321 0.0995103165972726 1.0 0.6017020369231328 5 Q9BT22,Q96AA3 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6980838143461245 1.6440563343205818 0.1001645664397481 1.0 0.6017020369231328 6 P04439,Q5KU26,P10321 3
Er to golgi anterograde transport 0.3871457170113986 1.6377484520582488 0.1014741787218558 1.0 0.6057964918545127 74 Q9Y6Y8,O15498,Q15363,Q96PC5,Q13509,Q9Y296,Q9Y3B3,P53634,P24390,Q9HCU5,Q14789,Q13561,O95249,O75935,Q5JRA6,P62820,Q9BVK6,P49755,O75396 19
Rhod gtpase cycle 0.4761378875696725 1.5858983980382253 0.1127623592889603 1.0 0.6126214576153465 27 P20700,Q8NHP6,P50402,Q8TAA9,Q9UEY8,O15173,Q14739,P42167 8
G alpha z signalling events 0.6839972961684582 1.5770418718895156 0.1147858908135082 1.0 0.6126214576153465 6 P63096,P63218,P04899,Q9UBI6 4
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6311923549579113 1.566628377618674 0.1172015807969655 1.0 0.6126214576153465 8 Q16850,P04035 2
Striated muscle contraction 0.8135091367916294 1.5658985571324884 0.1173723677087557 1.0 0.6126214576153465 4 P08670 1
Heme degradation 0.9466384310764906 1.564276621547465 0.1177526199197367 1.0 0.6126214576153465 3 P09601 1
Biological oxidations 0.4500297873282795 1.5621399155614362 0.1182550314372163 1.0 0.6126214576153465 41 P16435,Q9NX62,Q8TB61,Q9UJ14,Q16850,O43169,Q9NUJ1,P21964,Q99735 9
Iron uptake and transport 0.5101809180444413 1.5568463461799618 0.1195069705835893 1.0 0.6126214576153465 18 P30519,P09601,Q93050 3
Unfolded protein response upr 0.4557047774508003 1.5558801697111897 0.1197365896963589 1.0 0.6126214576153465 38 O95070,P02545,Q9NWM8,Q9NQT5,P43307,Q9Y5M8,O76024 7
Autophagy 0.4221092216545857 1.5532620392946184 0.1203605452595943 1.0 0.6126214576153465 51 Q15382,Q8IWA4,Q8N4H5,Q15388,Q9NS69,P21796,Q7Z3C6,O96008,P08670,P13473 10
Diseases associated with glycosaminoglycan metabolism 0.8096012471293887 1.54980732893861 0.1211877674328361 1.0 0.6126214576153465 4 Q8NCH0,P06865 2
Asparagine n linked glycosylation 0.4209962212474751 1.5373898110338255 0.1241978799766554 1.0 0.6126214576153465 115 Q9Y6Y8,O15498,Q15363,Q96PC5,Q13509,Q9BT22,Q96AA3,Q9Y296,P10619,Q9Y3B3,Q9UBV2,Q9GZP9,P16278,P53634,Q9BUN8,P24390,Q9HCU5,Q14789,Q13561,O95249,P04843,O75935,Q5JRA6,P62820,P27824,O60858,Q16706,Q9BVK6,Q86YN1,P49755,O75396,Q04323,P46977,Q2TAA5 34
Peroxisomal lipid metabolism 0.5616712686924046 1.5271975937309272 0.1267118844913661 1.0 0.6184429169385626 12 Q9BY49,O43808,P51648,O15254,Q5T8D3 5
Maturation of sars cov 2 spike protein 0.58361371294434 1.5112844809829111 0.1307159861669216 1.0 0.6335398493316653 10 P27824,Q16706,P46977 3
Synthesis of pc 0.7007617958713546 1.504431459042193 0.1324703091625008 1.0 0.6351307929894153 5 P35790 1
Gaba b receptor activation 0.7000287370247347 1.5011095060286712 0.1333272405125156 1.0 0.6351307929894153 5 P63096,P63218,P04899 3
Gaba receptor activation 0.7000287370247347 1.5011095060286712 0.1333272405125156 1.0 0.6351307929894153 5 P63096,P63218,P04899 3
Adp signalling through p2y purinoceptor 12 0.7000287370247347 1.5011095060286712 0.1333272405125156 1.0 0.6351307929894153 5 P63096,P63218,P04899 3
Intra golgi and retrograde golgi to er traffic 0.3977945621611145 1.4986687243850805 0.133959594213666 1.0 0.6359651725297248 95 O15498,Q15363,Q13509,P52732,Q9P2W9,Q8N2H4,Q9Y3B3,P24390,Q9NSK0,Q8TBA6,Q13561,O95249,Q8N6T3,O43493,Q12981,Q99747,P40616,O75935,P62820,O60499,Q8TD16,P33176,Q16706,Q9BVK6,Q13409,P49755,O75396,O00461,Q9H0U4,Q9Y496,Q10472,Q6NUQ1,Q14746 33
Basigin interactions 0.6664098408467523 1.4928843262677842 0.1354674686163934 1.0 0.6366055704236598 6 P53985,P08195,P54709,P35613 4
Heme biosynthesis 0.6640243845367276 1.481430746697851 0.1384918265279187 1.0 0.642140435667783 6 Q7KZN9 1
Synthesis of pe 0.93041317179248 1.4780943779786822 0.13938251868352 1.0 0.6436784637828024 2 P35790 1
Diseases of glycosylation 0.4914846182738034 1.4700065710551409 0.141559974312867 1.0 0.6439726422557575 19 P16278,Q9BT22,Q8NCH0,Q96AA3,Q96L58,P06865,P10619,O43505,Q2TAA5 9
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5830634545906315 1.4430206704324868 0.1490146484752648 1.0 0.6559473924971307 9 P09601 1
Cell death signalling via nrage nrif and nade 0.6291325515294321 1.4287887186251378 0.1530649690276768 1.0 0.6649181163295281 7 Q92542 1
Synthesis of pg 0.9111249223119906 1.427476333048454 0.1534426422298911 1.0 0.6649181163295281 3 Q8IV08,Q8N2A8 2
Diseases of carbohydrate metabolism 0.5789856220770406 1.4204543076077711 0.155475461927228 1.0 0.6688772622797453 9 P10253,P16278,P34059,P54802 4
Signal amplification 0.5777312650174853 1.4135054318595308 0.1575071653853259 1.0 0.6720627823649951 9 P50148,P63096,P63218,P04899 4
Hs gag degradation 0.9102205653929758 1.395403659159156 0.1628941485151203 1.0 0.6929228152432181 2 P54802 1
Mucopolysaccharidoses 0.7681069319241329 1.3782460696131522 0.1681273277863142 1.0 0.7016697598397182 4 P16278,P34059,P54802 3
Organelle biogenesis and maintenance 0.3895767164722723 1.3777261104003344 0.1682878666728546 1.0 0.7016697598397182 97 O75935,P41208,P06576,Q5XKP0,O94927,P56385,P24539,Q9Y512,Q13505,Q16891,Q9BUR5,Q6UXV4,O75964,Q13561,Q10713,O75431,Q9H6D7,Q9NX63 18
Golgi to er retrograde transport 0.3571595667603071 1.3602552189208117 0.1737491739894239 1.0 0.7098355366965897 68 Q15363,Q13509,Q9P2W9,Q9Y3B3,P24390,Q9NSK0,Q13561,Q12981,Q99747,O75935,P62820,Q8TD16,Q9BVK6,P49755,O75396,Q9H0U4,Q9Y496,Q10472,Q6NUQ1 19
Phase i functionalization of compounds 0.5190697510487476 1.3395177350919787 0.1804021847925843 1.0 0.7223441592213085 13 Q16850,O43169 2
Vitamin d calciferol metabolism 0.8871911366958747 1.3351829306211866 0.1818164821106558 1.0 0.7225906474740635 3 P04062 1
Attachment of gpi anchor to upar 0.6577271435516453 1.3083727369935283 0.1907469150441156 1.0 0.7495168328428387 5 Q96S52,Q92643 2
Retrograde transport at the trans golgi network 0.4421028277683926 1.2990306313253792 0.1939334172371478 1.0 0.7552443642220371 24 Q8N2H4,O60499 2
Alpha oxidation of phytanate 0.748707913647474 1.2977410421585078 0.1943763352922281 1.0 0.7552443642220371 4 P51648,O43808 2
Transport and synthesis of paps 0.8847468157812937 1.291337738079816 0.196586590096913 1.0 0.7559938013854083 2 Q8TB61 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7460271337374018 1.2866091832322788 0.1982305412750675 1.0 0.7559938013854083 4 P67812 1
Incretin synthesis secretion and inactivation 0.7460271337374018 1.2866091832322788 0.1982305412750675 1.0 0.7559938013854083 4 P67812 1
Miscellaneous transport and binding events 0.652674129353229 1.2852399319581091 0.1987084534918484 1.0 0.7559938013854083 5 Q9H0U3,Q9UEY8,Q8TDW0,P35611 4
Endosomal vacuolar pathway 0.744971146460047 1.2822240077203182 0.1997640767277846 1.0 0.7559938013854083 4 P10321,Q9UIQ6 2
Aquaporin mediated transport 0.6204878281223342 1.271038512858376 0.2037149478048108 1.0 0.7591713379776597 6 P10644,Q99797 2
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7372960836192328 1.2503502741375607 0.2111716208424869 1.0 0.7646170721026398 4 P12235,P12236 2
Response to elevated platelet cytosolic ca2 0.4265606871272784 1.2484911886646883 0.2118512332255011 1.0 0.7646170721026398 34 Q96JJ7,O43852,P07602,Q8NBX0,Q9NZJ7,Q6UXV4,P05067,P13473,O94919 9
Phase ii conjugation of compounds 0.4336248039890011 1.246612585558515 0.212539584736537 1.0 0.7646170721026398 27 Q9NX62,Q8TB61,Q9UJ14,Q9NUJ1,P21964,Q99735 6
Acyl chain remodelling of pg 0.8720099409754547 1.2394890805407637 0.2151644301267317 1.0 0.7646170721026398 2 Q8NF37 1
O linked glycosylation of mucins 0.6424895597356002 1.23856796533033 0.2155055377189247 1.0 0.7646170721026398 5 Q8N4A0,Q10472,O43505 3
O linked glycosylation 0.6424895597356002 1.23856796533033 0.2155055377189247 1.0 0.7646170721026398 5 Q8N4A0,Q10472,O43505 3
Bile acid and bile salt metabolism 0.5913000029926477 1.2371600098125854 0.2160276846415079 1.0 0.7646170721026398 7 Q9BZF3,P22307,Q9BXW6,P51659 4
Synthesis of bile acids and bile salts 0.5913000029926477 1.2371600098125854 0.2160276846415079 1.0 0.7646170721026398 7 Q9BZF3,P22307,Q9BXW6,P51659 4
Cytosolic sulfonation of small molecules 0.637063030449374 1.2136804086006006 0.2248697884528119 1.0 0.7819846893446535 5 Q9NX62,Q8TB61 2
Peptide hormone metabolism 0.486879859331753 1.2075220827425586 0.2272311459381719 1.0 0.7850819174580401 14 P67812,Q96HE7,Q9UPT5,O75787,Q15005,P33176 6
Signaling by braf and raf1 fusions 0.448727218955535 1.203699890388602 0.2287055946578844 1.0 0.7874492132898941 20 P02545,O43252,Q53H12,Q9NRY5 4
Tp53 regulates transcription of cell death genes 0.7232578999037711 1.192063436233611 0.2332363724894834 1.0 0.79517596601194 4 Q92696 1
Wax and plasmalogen biosynthesis 0.7221013366490456 1.1872632807928745 0.2351237869716418 1.0 0.7996508256174908 4 O00116,Q6IAN0,O15228 3
Abc transporter disorders 0.4040259633079336 1.1828608293363638 0.2368643079333865 1.0 0.7996964769634398 43 Q9BUN8,Q9UL46,P28072,P61289,Q9NP58,P49721,Q9UBV2,Q9GZP9,O00231 9
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4567982764191332 1.1822655745764123 0.2371003406138128 1.0 0.7996964769634398 18 Q86YN1,Q9BT22,Q96AA3,P10619 4
Translation of sars cov 1 structural proteins 0.6018655420044027 1.1804735793817982 0.2378119125899545 1.0 0.7996964769634398 6 Q10472 1
Metabolism of steroid hormones 0.624705836570803 1.1569771938169713 0.2472816781713447 1.0 0.8186266483049941 5 Q8NBQ5,P30536,Q53GQ0 3
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.839417653463326 1.1514678186747758 0.2495398272432254 1.0 0.8190604240732103 3 Q92696 1
Sulfur amino acid metabolism 0.5307507614047078 1.151167633184226 0.2496632780783905 1.0 0.8190604240732103 9 Q9UBX3 1
Sialic acid metabolism 0.6195216971011357 1.133184612105828 0.2571367348261275 1.0 0.8288299427474505 5 P10619 1
Activation of ampk downstream of nmdars 0.5483971366324355 1.1280618615806046 0.2592937944446603 1.0 0.8288299427474505 8 Q13131,P54619,Q13509,P54646,P04350,Q9BVA1,Q13885 7
Copi mediated anterograde transport 0.372971537354456 1.1141090031215108 0.2652324267312713 1.0 0.8288299427474505 53 O75935,Q99747,O15498,Q9BVK6,Q15363,P62820,P24390,P49755,Q13509,Q9H0U4,Q14789,Q13561,O95249,Q9Y3B3 14
Adrenaline noradrenaline inhibits insulin secretion 0.7031395710289013 1.1086498755754413 0.2675812531265773 1.0 0.8288299427474505 4 P63096,P63218,P04899 3
Platelet calcium homeostasis 0.7022798088131808 1.1050904578247325 0.2691203948853329 1.0 0.8288299427474505 4 P20020,P16615 2
Reduction of cytosolic ca levels 0.702279808813181 1.1050904578247325 0.2691203948853329 1.0 0.8288299427474505 4 P20020,P16615 2
Pre notch expression and processing 0.5121767456519162 1.101990711963649 0.270465709568856 1.0 0.8288299427474505 10 Q9UBV2,Q15363,P16615 3
Purinergic signaling in leishmaniasis infection 0.700511509045903 1.097771448442293 0.2723043018228503 1.0 0.8288299427474505 4 P09601 1
The nlrp3 inflammasome 0.7005115090459031 1.097771448442293 0.2723043018228503 1.0 0.8288299427474505 4 P09601 1
Inflammasomes 0.700511509045903 1.097771448442293 0.2723043018228503 1.0 0.8288299427474505 4 P09601 1
Adp signalling through p2y purinoceptor 1 0.6107826102265229 1.0930843927723843 0.2743567478424149 1.0 0.8332537909362427 5 P50148,P63218 2
Cell surface interactions at the vascular wall 0.4481328062811928 1.0856696453494736 0.2776251748845961 1.0 0.8363353524953263 17 P14174,P53985,P78310,Q92896,Q08722,P35613,P54709 7
Apoptotic cleavage of cellular proteins 0.4313509009788107 1.074777132333714 0.2824745209373587 1.0 0.840177635833447 20 P08670,P02545,P51572,P49354 4
Rab geranylgeranylation 0.4311633757250643 1.073381518546463 0.2830999732257866 1.0 0.840177635833447 20 P61026,Q969Q5,P62820,P61019,Q9BZG1,Q92696 6
Aflatoxin activation and detoxification 0.6942556453481621 1.071899109594112 0.2837653501966364 1.0 0.840177635833447 4 Q9UJ14 1
Chaperone mediated autophagy 0.5588462333549291 1.071730606536112 0.2838410495032351 1.0 0.840177635833447 7 P13473 1
Copii mediated vesicle transport 0.4107697581079987 1.0716336626020853 0.2838846073628469 1.0 0.840177635833447 29 Q9Y6Y8,O15498,P53634,Q15363,P62820,P49755,O75396,Q9Y296,Q9HCU5,Q99747 10
G alpha i signalling events 0.4106623541191284 1.0518151165597824 0.2928843821935014 1.0 0.8559093117374225 25 P50148,P10644,P52292,P07602,P04899,Q9NZJ7,P63096,P05067,P63218 9
Insulin receptor recycling 0.5028635389901677 1.0480930643752926 0.2945957314342877 1.0 0.8559093117374225 10 Q93050,P61421,P36543,Q15904,Q9Y487 5
Hs gag biosynthesis 0.8238583410997105 1.0454456376376629 0.2958170532943363 1.0 0.8559093117374225 2 Q7LGA3 1
Pyruvate metabolism 0.4390883053960437 1.022283249796086 0.3066468586919835 1.0 0.8722817595921248 17 P48163,P21796,P09622,P35613 4
Rac3 gtpase cycle 0.40035276106291 1.0138607279481775 0.3106492129727591 1.0 0.8745256853218308 33 O15498,P50402,Q8TAA9,O15173,O75962,P42167,Q14739,Q01968 8
Metabolism of lipids 0.4377212236567168 1.0016935049857758 0.3164916445679628 1.0 0.8782822160760144 191 P38435,O43681,Q15392,P35790,P30536,Q96N66,Q8NAN2,Q96G23,O15269,Q15800,Q9UKU0,P10619,Q10713,P40939,Q9NZ01,P06865,Q16836,P53007,Q92604,O95674,P16278,P50897,P07602,P17900,Q8N2A8,Q9P035,P06280,P09960,Q13510,Q9NUQ2,P51648,Q9H7Z7,P50416,Q16850,O95470,Q9BVG9,P48651,P48163,Q15165,Q16739,Q14534,Q53GQ0,P04062,Q16880,Q15125,P23786,Q14739,Q9UG56,P37268,Q9HCL2,Q9NZJ7,Q9NPH0,P04035,Q8IV08,Q53H12,O00116,O15254,Q06136,Q8NF37 59
Rnd2 gtpase cycle 0.426237906224909 0.9988502560114167 0.317867236498522 1.0 0.8782822160760144 19 Q07065 1
Disorders of transmembrane transporters 0.3361373766644505 0.9973395569705418 0.3185997191740632 1.0 0.8782822160760144 76 Q8NFH5,O00400,Q9BUN8,Q9UL46,P28072,P61289,Q9NP58,P35613,Q8NFH4,Q9BTX1,P49721,Q9UBV2,Q9GZP9,O00231 14
Cytochrome p450 arranged by substrate type 0.7975202719684471 0.9920612599236458 0.3211676429432684 1.0 0.8782822160760144 3 Q16850 1
Hyaluronan uptake and degradation 0.6747795436782666 0.9916170633840482 0.3213843623168162 1.0 0.8782822160760144 4 P06865 1
Hyaluronan metabolism 0.6747795436782664 0.9916170633840482 0.3213843623168162 1.0 0.8782822160760144 4 P06865 1
Synaptic adhesion like molecules 0.5420461887575688 0.986054599694102 0.3241063206254946 1.0 0.8805310390430917 7 O95197,O75955,Q12959 3
Defective cftr causes cystic fibrosis 0.3831582344804942 0.9708997045091462 0.3315982253347262 1.0 0.8921724012390798 42 Q9BUN8,Q9UL46,P28072,P61289,P49721,Q9UBV2,Q9GZP9,O00231 8
Transferrin endocytosis and recycling 0.4791697340552059 0.9656621011821802 0.3342132895034855 1.0 0.8937220201889826 11 Q93050,P61421,P36543,Q15904,Q9Y487 5
Adora2b mediated anti inflammatory cytokines production 0.4977029010536554 0.9652584671196972 0.3344153688749594 1.0 0.8937220201889826 9 P10644,P63218,P04899 3
Abc transporters in lipid homeostasis 0.7902423865755053 0.9646506705233798 0.3347198107757103 1.0 0.8937220201889826 3 P40855,P56589 2
Beta oxidation of pristanoyl coa 0.6650958354107798 0.9518949729010596 0.3411502493090637 1.0 0.895724109764904 4 O15254 1
Abc family proteins mediated transport 0.3542449769436021 0.945306805862442 0.3445022648184979 1.0 0.8976470503309449 54 Q9NRK6,O75477,Q9BUN8,Q9UL46,P28288,P61289,P28072,Q9NUT2,Q9NP58,O94905,P28070,P56589,P40855,P49721,Q9UBV2,Q9GZP9,O00231 17
Transport of bile salts and organic acids metal ions and amine compounds 0.7820038591892049 0.933751282058228 0.3504322051846535 1.0 0.9016554275033466 3 Q15043 1
Dna damage recognition in gg ner 0.4214194231434709 0.9295108426459572 0.3526244087432211 1.0 0.9016554275033466 18 P41208,P54725,Q9BT78,Q92905,Q7L5N1 5
Synthesis secretion and deacylation of ghrelin 0.7777385926215177 0.9178125891448032 0.35871699024944 1.0 0.9032209657921634 3 P67812 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7777385926215177 0.9178125891448032 0.35871699024944 1.0 0.9032209657921634 3 P67812 1
Copi dependent golgi to er retrograde traffic 0.3673620003979943 0.9102706987461848 0.3626797673225848 1.0 0.9077778262702324 47 Q99747,Q9BVK6,Q6NUQ1,Q15363,P62820,P24390,P49755,Q13509,O75396,P52732,Q9NSK0,Q9P2W9,Q9H0U4,Q9Y496,Q12981,Q9Y3B3 16
Ros and rns production in phagocytes 0.4878646911119268 0.9099477093464198 0.3628500872798341 1.0 0.9077778262702324 9 Q93050 1
Notch3 activation and transmission of signal to the nucleus 0.7878223050636716 0.9035049929329392 0.3662579395373346 1.0 0.9097585605293438 2 Q92542 1
The phototransduction cascade 0.5674251969129507 0.8949287956381976 0.3708251524767585 1.0 0.9150965820598423 5 P49354,P53582 2
Binding and uptake of ligands by scavenger receptors 0.5045709800849809 0.8936566215023632 0.3715056413991462 1.0 0.9150965820598423 8 Q8WTV0 1
Downregulation of erbb2 signaling 0.537961490045009 0.8698738880070702 0.3843693267876134 1.0 0.9303329683434534 6 Q16543,P31751 2
Syndecan interactions 0.6448432698674111 0.8693911006150186 0.3846332490718886 1.0 0.9303329683434534 4 P05556,Q9Y296 2
Proton coupled monocarboxylate transport 0.7788132960546643 0.8686484781146506 0.3850394300362425 1.0 0.9303329683434534 2 P35613 1
Hedgehog ligand biogenesis 0.3750678140246453 0.8668419457607953 0.3860286158530117 1.0 0.9306166458432223 40 P28072,P49721,Q9UBV2,Q9GZP9,O00231 5
Activation of nmda receptors and postsynaptic events 0.3871470513409708 0.8590548324569228 0.390310265076651 1.0 0.93602321893881 23 P10644,P52292,P07196,Q14168,P51812,Q12959 6
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4780162215808396 0.8546873800939225 0.3927242388194192 1.0 0.93602321893881 9 P38435,O60725 2
Adenylate cyclase inhibitory pathway 0.7601820020576755 0.8526812331730992 0.3938361008130999 1.0 0.93602321893881 3 P04899 1
Metabolism of steroids 0.3631544750947517 0.8496749714248106 0.3955058172696475 1.0 0.93602321893881 46 P38435,Q15392,P37268,Q9HCL2,P30536,Q53GQ0,Q14534,P04062,P04035,Q15800,Q16850,Q15125,Q14739 13
Translation of sars cov 2 structural proteins 0.4184713043296327 0.8493737293718223 0.3956733664529261 1.0 0.93602321893881 16 P27824,Q16706,P46977,Q10472 4
Copi independent golgi to er retrograde traffic 0.3849688110827064 0.8461529670133741 0.3974674157952109 1.0 0.9370189618319243 26 O75935,Q10472,Q13561 3
Ub specific processing proteases 0.3194108268146374 0.8437245092530655 0.3988233683919988 1.0 0.9370189618319243 72 Q9UL46,P28072,P61289,P04637,P45880,Q9Y277,Q9UPU5,P21796,Q969V5,P49721,O00231 11
Diseases associated with o glycosylation of proteins 0.7679403541472507 0.8269862597314932 0.4082448494543551 1.0 0.9370189618319243 2 O43505 1
Plasma lipoprotein remodeling 0.7673190431811049 0.824619906543421 0.4095874161655761 1.0 0.9370189618319243 2 Q9BU23 1
Aurka activation by tpx2 0.376280557184985 0.8143496589635204 0.4154446689176962 1.0 0.9370189618319243 34 O75935,P41208,O94927,O75330,Q13561,Q9H6D7 6
Rho gtpases activate ktn1 0.5078434471939753 0.8125177906535735 0.4164945824054644 1.0 0.9370189618319243 7 Q9NSK0,P84095,Q86UP2 3
Transport of connexons to the plasma membrane 0.5478855721392968 0.8065945187346091 0.4199001327162959 1.0 0.9370189618319243 5 Q9BVA1,Q13885,Q13509,P04350 4
Gap junction assembly 0.5478855721392968 0.8065945187346091 0.4199001327162959 1.0 0.9370189618319243 5 Q9BVA1,Q13885,Q13509,P04350 4
Platelet homeostasis 0.4431111999188381 0.8043472999637424 0.4211964277614592 1.0 0.9370189618319243 12 P63218,P20020,P16615 3
Beta oxidation of lauroyl coa to decanoyl coa coa 0.6239534261973905 0.7853558010519992 0.4322449874377698 1.0 0.9462628181498212 4 P40939 1
Beta oxidation of hexanoyl coa to butanoyl coa 0.6239534261973905 0.7853558010519992 0.4322449874377698 1.0 0.9462628181498212 4 P40939 1
Metabolism of cofactors 0.5195210345805238 0.7812484535043515 0.4346563807518127 1.0 0.9462628181498212 6 P00374,O75208 2
Ion homeostasis 0.4469584774011275 0.7741572568626484 0.4388378014092593 1.0 0.9462628181498212 11 P05023,P20020,P23634,P16615 4
Wnt ligand biogenesis and trafficking 0.5404205601964169 0.7731091504562894 0.4394577861429076 1.0 0.9462628181498212 5 Q5T9L3 1
Regulation of tp53 activity through association with co factors 0.7377814230617963 0.7708915189729559 0.4407712345272689 1.0 0.9476240915416246 3 P04637 1
Ptk6 regulates proteins involved in rna processing 0.7333961480564211 0.755080543286728 0.4502006566651051 1.0 0.9575368706745584 3 P23246 1
Signaling by notch 0.3242501003395248 0.7352217006465007 0.4622044849518767 1.0 0.9711227314590488 58 Q15363,P28072,P61289,P04637,Q92542,P49721,Q9UBV2,P16615,O00231 9
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7433985709847742 0.7348349883129786 0.4624399956649765 1.0 0.9711227314590488 2 O00767 1
G alpha 12 13 signalling events 0.4917621054065191 0.7318115154348818 0.4642836194916029 1.0 0.9711227314590488 7 O75962 1
Beta oxidation of butanoyl coa to acetyl coa 0.722456425900904 0.7159615174514113 0.4740151111900923 1.0 0.9711227314590488 3 P40939 1
Thromboxane signalling through tp receptor 0.5965302803604522 0.6772922903159814 0.4982205215325082 1.0 0.9957252089823548 4 P50148,P63218 2
Unwinding of dna 0.4446340683342561 0.6690855409636284 0.5034409128401272 1.0 0.9980437595135284 9 P33991,Q9BRT9,Q14566,Q9Y248 4
Long term potentiation 0.4938373784969386 0.6596054122022048 0.5095070801949138 1.0 0.9980437595135284 6 Q14168,P07196 2
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4598397186870356 0.6575515678703664 0.5108263244714624 1.0 0.9980437595135284 8 Q14168,P51812,P07196 3
Signaling by insulin receptor 0.3899827187760195 0.6543330209353864 0.5128972761504431 1.0 0.9980437595135284 16 Q93050,P61421,P36543,Q15904,Q9Y487,P31751 6
G beta gamma signalling through pi3kgamma 0.7029210689869371 0.6473875087154953 0.5173811782599749 1.0 1.0 3 P63218,P31751 2
G protein activation 0.7029210689869357 0.6473875087154912 0.5173811782599775 1.0 1.0 3 P50148,P63218 2
Vasopressin regulates renal water homeostasis via aquaporins 0.5101222161595163 0.6392869607697871 0.522636269428276 1.0 1.0 5 P10644 1
Glucagon signaling in metabolic regulation 0.5101222161595163 0.6392869607697871 0.522636269428276 1.0 1.0 5 P10644 1
Recruitment of mitotic centrosome proteins and complexes 0.3559550870951738 0.632121809969938 0.5273072846845701 1.0 1.0 33 O75935,P41208,Q9H6D7,Q13561 4
Prevention of phagosomal lysosomal fusion 0.5847062480571836 0.6317036916634056 0.5275805153052913 1.0 1.0 4 P20339,O14964,Q9H267 3
Cdc42 gtpase cycle 0.3570687896665338 0.6316832146397859 0.527593898419739 1.0 1.0 31 O15498,Q8TAA9,P42166,Q68EM7,Q86YQ8,P27105,Q86UP2,O75962,Q14739,P42167 10
Oncogenic mapk signaling 0.3568513864366203 0.616799744392216 0.5373668206092574 1.0 1.0 25 Q7Z569,P02545,Q9NRY5,O43252,Q53H12,O00203 6
Anchoring of the basal body to the plasma membrane 0.3529697248235028 0.6123934214717152 0.5402774932452008 1.0 1.0 34 O75935,P41208,Q9H6D7,Q13561 4
Regulation of plk1 activity at g2 m transition 0.3503028310907444 0.6109533452861202 0.5412304673463368 1.0 1.0 37 O75935,P41208,O94927,O95684,Q13561,Q13616,Q96CS2,Q9H6D7 8
Assembly and cell surface presentation of nmda receptors 0.4184893557986229 0.6072479781469553 0.5436863563767376 1.0 1.0 11 Q14168,Q12959,P07196 3
N glycan antennae elongation in the medial trans golgi 0.7061199130164548 0.6010779118300005 0.5477880944090938 1.0 1.0 2 Q16706 1
Reactions specific to the complex n glycan synthesis pathway 0.7061199130164548 0.6010779118300005 0.5477880944090938 1.0 1.0 2 Q16706 1
Signaling by gpcr 0.3401008598727416 0.5952914057275178 0.5516486996962855 1.0 1.0 44 P50148,P10644,P52292,P07602,P42892,Q9NZJ7,P05067,P51812,O75962,Q8NCG7,P31751,P63218,Q8N2K0 13
Glycerophospholipid catabolism 0.7030133581857689 0.5903341346254057 0.5549666589168285 1.0 1.0 2 Q8IY17 1
Potassium channels 0.7027027027026913 0.5892635231708985 0.5556845102594972 1.0 1.0 2 P63218 1
Glucagon type ligand receptors 0.7027027027026913 0.5892635231708985 0.5556845102594972 1.0 1.0 2 P63218 1
Prostacyclin signalling through prostacyclin receptor 0.7027027027026913 0.5892635231708985 0.5556845102594972 1.0 1.0 2 P63218 1
Presynaptic function of kainate receptors 0.7027027027026913 0.5892635231708985 0.5556845102594972 1.0 1.0 2 P63218 1
Inwardly rectifying k channels 0.7027027027026913 0.5892635231708985 0.5556845102594972 1.0 1.0 2 P63218 1
Linoleic acid la metabolism 0.7002174588381441 0.580723634666943 0.5614267300394034 1.0 1.0 2 P33121 1
Negative regulation of nmda receptor mediated neuronal transmission 0.4963780470184922 0.5800127265155485 0.5619060355772079 1.0 1.0 5 Q14168,P07196 2
Unblocking of nmda receptors glutamate binding and activation 0.4963780470184922 0.5800127265155485 0.5619060355772079 1.0 1.0 5 Q14168,P07196 2
Ras activation upon ca2 influx through nmda receptor 0.4963780470184922 0.5800127265155485 0.5619060355772079 1.0 1.0 5 Q14168,P07196 2
Aspartate and asparagine metabolism 0.4957782733762805 0.5774508922529542 0.5636349033413188 1.0 1.0 5 Q9UJS0 1
Nuclear envelope ne reassembly 0.3315690664345473 0.5754508880694349 0.5649863964585118 1.0 1.0 48 Q9BTX1,P02545,Q8NFH5,P20700,Q92973,P50402,Q9BW27,Q9Y3E7,Q13509,Q8N1F7,Q86XL3,P42166,Q8NFH4,Q7Z3B4,Q14739,P42167 16
Josephin domain dubs 0.6812715821760487 0.5736278359108863 0.5662196710755201 1.0 1.0 3 P54725 1
Pi5p regulates tp53 acetylation 0.6811684275947641 0.5732826786854301 0.5664533114839161 1.0 1.0 3 Q8TBX8,P04637 2
Rhoj gtpase cycle 0.3546841291973974 0.5654723249989937 0.5717525429784236 1.0 1.0 22 Q6IAA8,O75323,Q8TAA9,P42166,P27105,O75962,P42167,Q86YQ8,Q01968 9
Class b 2 secretin family receptors 0.6777665928632196 0.5619357353126369 0.5741598051476826 1.0 1.0 3 P63218 1
Platelet activation signaling and aggregation 0.3047891117454056 0.5451374430044611 0.5856589922656852 1.0 1.0 59 Q96JJ7,P84095,O43852,P07602,O94919,Q9Y6I9,Q8NBX0,Q9NZJ7,Q6UXV4,P05067,Q8NCG7,P13473,P63218,Q8N2K0,Q08380,Q9NUQ9 16
Tp53 regulates transcription of death receptors and ligands 0.6658650032600608 0.5228038558883141 0.6011107560416862 1.0 1.0 3 P04637 1
Cd28 dependent pi3k akt signaling 0.6628561767228619 0.5130568534071231 0.6079115517720901 1.0 1.0 3 P31751 1
Meiotic synapsis 0.3677831255184866 0.5049964452075528 0.6135613327372953 1.0 1.0 16 P02545,P20700,Q9UH99,P38398,Q8WXH0,Q8WVM7 6
Vitamin c ascorbate metabolism 0.6713264989127019 0.4849591638869136 0.6277053129660999 1.0 1.0 2 P00387 1
Synthesis of substrates in n glycan biosythesis 0.3743415230344053 0.4790851422642121 0.6318780591633573 1.0 1.0 14 Q86YN1,P10619 2
Ikk complex recruitment mediated by rip1 0.5396331986322722 0.4654311263440769 0.6416227482164674 1.0 1.0 4 P61088,Q13546,O14920 3
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3615446825403012 0.4637378304197918 0.6428355898522549 1.0 1.0 16 P05067 1
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.6452620656764926 0.4573334847086097 0.6474313654452291 1.0 1.0 3 P00374 1
Cardiac conduction 0.3826707201668622 0.4428797255254713 0.6578527328865413 1.0 1.0 12 P05023,P20020,P23634,P16615 4
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6366580682425969 0.4309274839474339 0.6665210987548211 1.0 1.0 3 P51659 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4000622665006204 0.4301596700629662 0.6670794968316349 1.0 1.0 9 P62258,Q04917,P14635,Q9Y3B8,P61981,P06493,P31946,P63104 8
Antigen processing cross presentation 0.3114874266138621 0.4284288022029613 0.6683389589137465 1.0 1.0 51 Q03519,O00231,Q9UIQ6,Q9UL46,P04439,P61289,P28072,O75396,Q03518,P10321,P49721,Q9UBG0 12
Signaling by hedgehog 0.2985311840429505 0.4213571740042395 0.6734942865087827 1.0 1.0 57 P10644,P28072,P61289,P49721,Q9UBV2,Q9GZP9,O00231 7
Defective intrinsic pathway for apoptosis 0.3522008393350626 0.4027160983592169 0.6871570897155079 1.0 1.0 16 P05067,P02545,P20700 3
Tryptophan catabolism 0.6439888164026036 0.4010926967531654 0.6883518776244242 1.0 1.0 2 P08195 1
Rhof gtpase cycle 0.3487617058360082 0.3973114893897163 0.6911377758888038 1.0 1.0 17 P42167,P20700,Q8TAA9 3
Lysine catabolism 0.4210801922730838 0.393062498219036 0.6942733215567738 1.0 1.0 7 Q9BQT8 1
Trans golgi network vesicle budding 0.3259080030931698 0.3913192543429939 0.6955612684213881 1.0 1.0 36 P55327,P05067,O43493,Q9Y5X3,O60749,O00203 6
Regulated necrosis 0.3475192290855849 0.3891005353092446 0.6972017775041539 1.0 1.0 17 Q9UNE7,Q9Y3E7,P04637,O75955,P49327,Q16543,Q14254 7
Golgi associated vesicle biogenesis 0.3258628753245238 0.3698279093217262 0.7115107186665375 1.0 1.0 29 P55327,O43493,Q9Y5X3,O60749,O00203 5
Mitotic g2 g2 m phases 0.3001746517387762 0.369789270142738 0.7115395106274209 1.0 1.0 91 O75935,P41208,O94927,P28072,P61289,P04637,Q99640,Q96CS2,Q13561,O75330,P49721,Q9H6D7,O00231 13
Activation of bad and translocation to mitochondria 0.399937752878932 0.3586124411377771 0.7198850383854829 1.0 1.0 8 P62258,Q04917,Q9Y3B8,P61981,P31751,P31946,P63104 7
Regulation of commissural axon pathfinding by slit and robo 0.6115599751398477 0.3574214720730773 0.7207763045602911 1.0 1.0 3 O94813,Q9Y6N7 2
Nef mediated downregulation of mhc class i complex cell surface expression 0.4412313432835736 0.3559666566772407 0.7218655359053596 1.0 1.0 5 P04439,Q9BXS5,Q10567,O43747 4
Recruitment of numa to mitotic centrosomes 0.3200031038921967 0.3524801687318665 0.7244781884386282 1.0 1.0 38 O75935,P41208,Q68CZ6,O94927,O95684,Q13561,Q96CS2,Q9H6D7 8
Ripk1 mediated regulated necrosis 0.3721975780136178 0.3476768842355704 0.7280828585952643 1.0 1.0 11 Q14254,O75955,Q16543,Q9UNE7 4
Irak1 recruits ikk complex 0.6247281764523072 0.3465338220344072 0.7289415706173519 1.0 1.0 2 O14920 1
Beta oxidation of octanoyl coa to hexanoyl coa 0.4349034588193406 0.3321029517697537 0.739811521319159 1.0 1.0 5 P40939 1
Beta oxidation of decanoyl coa to octanoyl coa coa 0.4349034588193406 0.3321029517697537 0.739811521319159 1.0 1.0 5 P40939 1
Downregulation of erbb4 signaling 0.6113699906803272 0.3111055611248981 0.7557203736264064 1.0 1.0 2 Q96J02 1
Insulin processing 0.3764009962640076 0.3108630297509467 0.755904750909199 1.0 1.0 9 O60645,Q8IYI6,Q96HE7,Q9UPT5,Q8TAG9,Q86YB8,Q96KP1,P33176 8
Mastl facilitates mitotic progression 0.4923842088902804 0.3086645899608891 0.7575766824658123 1.0 1.0 4 P14635,P30154,P06493 3
Protein protein interactions at synapses 0.3371456608373634 0.3068120747119733 0.7589864169632896 1.0 1.0 16 Q14168,O95197,O75955 3
G protein beta gamma signalling 0.426029722604096 0.2994309310306499 0.7646112645954366 1.0 1.0 5 P63218 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.4115265997256707 0.2985318744253387 0.7652972522795234 1.0 1.0 6 P10644 1
Regulation of hmox1 expression and activity 0.3063001009077388 0.2911107121232406 0.7709666474716477 1.0 1.0 45 P28072,P49721,P09601,O00231 4
Activation of bh3 only proteins 0.3552508569647936 0.2894233154777811 0.7722574549358765 1.0 1.0 12 P62258,Q13625,Q04917,P04637,Q9Y3B8,P63167,P27348,P61981,P31751,P31946,P63104 11
Thrombin signalling through proteinase activated receptors pars 0.408799389806165 0.2877404242385549 0.7735454439282288 1.0 1.0 6 P63218 1
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.4076094038081074 0.2830628702596949 0.7771286432944966 1.0 1.0 6 P40939 1
Diseases of immune system 0.5992544268406245 0.2807806343867422 0.7788786578736437 1.0 1.0 2 O14920 1
Stabilization of p53 0.3107614033993608 0.2733201066338757 0.7846071606922767 1.0 1.0 38 P28072,P61289,P04637,P49721,O00231 5
Synthesis of pips at the golgi membrane 0.3808289461260281 0.2710112514230322 0.7863823786087623 1.0 1.0 8 Q9BTU6,Q9NTJ5,Q10713 3
Vitamin b5 pantothenate metabolism 0.4042414802572155 0.2699292643994126 0.7872146728122806 1.0 1.0 6 P49327,Q9Y289,P16260 3
Signaling by notch4 0.3055351209145852 0.2641489696601966 0.791665131130745 1.0 1.0 43 P28072,P49721,Q92542,O00231 4
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3118796383732117 0.2596228114913297 0.7951547385263571 1.0 1.0 29 O75935 1
Regulation of localization of foxo transcription factors 0.3996889580093257 0.2524292623061303 0.8007092842659416 1.0 1.0 6 Q9Y3B8,P61981,P31751,P31946,P63104 5
Ticam1 rip1 mediated ikk complex recruitment 0.5674331883157357 0.2427713743105142 0.8081825122387982 1.0 1.0 3 P61088,O14920 2
Caspase activation via extrinsic apoptotic signalling pathway 0.4696922598694536 0.2418060671436557 0.8089304375016644 1.0 1.0 4 Q13546,P49327,Q9UKG1 3
G alpha q signalling events 0.3346818715046468 0.2416390843116831 0.8090598344435851 1.0 1.0 14 Q8N2K0,P05067,P51812,Q8NCG7,P63218,O75962 6
Nuclear envelope breakdown 0.3053324699144525 0.2390964304693026 0.8110308095921799 1.0 1.0 40 P02545,P20700,P50402,Q8NFH4,Q9BTX1,P42167 6
Rhoc gtpase cycle 0.3081322613652609 0.2318771412722363 0.8166334393208969 1.0 1.0 32 O14578,P28288,Q8TAA9,P27105,O75955,Q14739,Q5T8D3,P42167 8
Pyruvate metabolism and citric acid tca cycle 0.3054323479706559 0.2237904220041389 0.8229203831035068 1.0 1.0 37 P48163,Q9H9P8,P21796,P09622,Q9P0J1,Q13423,P35613,P21912 8
Transcriptional regulation by runx3 0.3015973580886431 0.221053029144411 0.8250511428294087 1.0 1.0 42 P28072,P61289,P04637,P49721,O00231 5
Cdt1 association with the cdc6 orc origin complex 0.3031385560724855 0.2203491034519708 0.825599280756723 1.0 1.0 40 P28072,P49721,Q9Y619,O00231 4
Signaling by flt3 fusion proteins 0.4020522388059616 0.2162952515581422 0.8287576101749228 1.0 1.0 5 Q01082,Q92614,P62993,Q14789 4
Regulation of lipid metabolism by pparalpha 0.3130573144437574 0.2136390021357735 0.8308285821916734 1.0 1.0 20 P48163,P37268,P04035,P23786 4
Toll like receptor tlr1 tlr2 cascade 0.3195785057495799 0.2108765022032042 0.8329836403470872 1.0 1.0 17 P05067,Q9BQ95,P51812 3
G1 s dna damage checkpoints 0.300734634517214 0.1943070112419783 0.8459354960827918 1.0 1.0 39 P28072,P61289,P04637,P49721,O00231 5
Formyl peptide receptors bind formyl peptides and many other ligands 0.5448341078817285 0.1922242525890334 0.847566549316114 1.0 1.0 3 P05067 1
Neuronal system 0.2818705099251976 0.1836943007173867 0.8542532801973572 1.0 1.0 54 P10644,O95197,P52292,P07196,Q14168,Q13509,P51812,O75955,P63218,O75915,P21964,Q12959 12
Hemostasis 0.3169481230404106 0.175406366192687 0.8607603386395148 1.0 1.0 127 Q13509,P04899,P20020,Q9UIJ7,P16615,P10644,P07602,O43852,O43572,P23634,Q6UXV4,Q9NSK0,P05067,P63218,Q9NUQ9,O94919,Q96JJ7,P84095,Q9Y6I9,P42785,Q8NCG7,Q8N2K0,P54709,Q08380,P50148,Q8IWA4,O95140,P04637,Q9NZJ7,Q8NBX0,Q92896,P13473,Q08722,P35613 34
Muscle contraction 0.299712751449276 0.1723047615222595 0.8631979411858179 1.0 1.0 26 P23634,P20020,P05023,P67936,P16615,P08670 6
Synthesis of ip2 ip and ins in the cytosol 0.5332711193953806 0.1686700588511334 0.8660561708822088 1.0 1.0 3 Q96PE3 1
Sensory processing of sound 0.313884555382213 0.1664880735572538 0.8677728681134893 1.0 1.0 16 P56545,Q00013,P23634,Q13813,P15311,P47756,P35579,P20020,O14936,Q6IBS0,Q9Y2J2,P26038,Q01082,O00159,P35241 15
Interleukin 1 signaling 0.2940965205291159 0.1636755927674606 0.8699865325493406 1.0 1.0 43 P28072,P61289,P05067,P49721,O00231 5
Plasma lipoprotein clearance 0.3147863548160025 0.1634972471671818 0.8701269404314138 1.0 1.0 15 O15118,Q8WTV0 2
Tyrosine catabolism 0.536191363777568 0.1527863885128234 0.8785667320952086 1.0 1.0 2 O43708 1
Tysnd1 cleaves peroxisomal proteins 0.3815610571284458 0.1519979848772592 0.8791885250202451 1.0 1.0 5 O00116 1
Regulation of pyruvate dehydrogenase pdh complex 0.3408880986859784 0.1475434397289554 0.8827030949415997 1.0 1.0 9 P09622 1
Constitutive signaling by overexpressed erbb2 0.4299036369288257 0.1406730503627695 0.8881282360465874 1.0 1.0 4 Q96RT1,P07900,Q16543 3
Trafficking and processing of endosomal tlr 0.5222118670394384 0.1313898407208653 0.8954669249235412 1.0 1.0 2 Q99538 1
Diseases associated with glycosylation precursor biosynthesis 0.3463554930335419 0.1276719687432733 0.8984085742192902 1.0 1.0 8 P10619 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5049720323182184 0.1178303116479129 0.9062021116214936 1.0 1.0 3 P54646,P54619 2
Phosphorylation of emi1 0.5009322560596736 0.1113676045709763 0.9113248480322718 1.0 1.0 3 P53350,P06493 2
Activation of smo 0.507300403852111 0.1112990845827393 0.9113791812938852 1.0 1.0 2 Q9Y496 1
Inactivation of cdc42 and rac1 0.4140503574759165 0.1066557425048049 0.9150620946201116 1.0 1.0 4 O94813,Q9Y6N7,P60953 3
Suppression of phagosomal maturation 0.3487865588052249 0.1035729582890666 0.9175082483803996 1.0 1.0 7 Q9UI12,Q14974,P20339,O14964,Q9H267,P51149 6
Regulation of insulin secretion 0.3175608189458842 0.0992441706585783 0.9209444048314728 1.0 1.0 12 P50148,P10644,P63218,P04899 4
Rhot1 gtpase cycle 0.4970487729108406 0.0990708484811017 0.9210820177355026 1.0 1.0 2 P52306 1
Signaling by notch1 pest domain mutants in cancer 0.3291709924341444 0.0990132486046052 0.9211277509307418 1.0 1.0 9 Q92542 1
Pregnenolone biosynthesis 0.4921668132159833 0.0980254718542353 0.9219120671547494 1.0 1.0 3 P30536 1
Activation of kainate receptors upon glutamate binding 0.4083811113472975 0.0953997376148898 0.923997324481985 1.0 1.0 4 P63218 1
Visual phototransduction 0.3247587954818693 0.0951062553249911 0.9242304295700252 1.0 1.0 10 P49354,P53582 2
Sensory processing of sound by outer hair cells of the cochlea 0.3162979121221593 0.0934166976845905 0.9255725256893514 1.0 1.0 12 Q00013,P23634,Q13813,P15311,P35579,O14936,Q6IBS0,Q9Y2J2,P26038,Q01082,P35241 11
Extracellular matrix organization 0.2895662497197589 0.0925756129191095 0.9262407186010916 1.0 1.0 29 P13674,Q92542,Q9Y296,P05067,O15460,Q08722,P35613 7
Chylomicron assembly 0.4895930413171656 0.0909592802736752 0.9275249465131916 1.0 1.0 2 P07237 1
Plasma lipoprotein assembly remodeling and clearance 0.2958788420444448 0.0908007897385154 0.9276508825246506 1.0 1.0 19 Q9BU23,P61916,O15118,Q8WTV0 4
Glycogen breakdown glycogenolysis 0.336441594384579 0.0907008151700771 0.927730322890962 1.0 1.0 8 P10253,P35573 2
Other interleukin signaling 0.4863269111249306 0.0896502908767777 0.9285651189313832 1.0 1.0 3 Q12846,P40222 2
Regulation of runx3 expression and activity 0.2886362267831881 0.0887285511680572 0.9292976414685944 1.0 1.0 37 P28072,P61289,P49721,O00231 4
Arms mediated activation 0.4853946550652738 0.088351088669459 0.9295976347904428 1.0 1.0 3 Q9ULH0,P46108 2
Ca dependent events 0.3504839754314284 0.0848361376177938 0.9323916634242936 1.0 1.0 6 P10644 1
Notch2 intracellular domain regulates transcription 0.4790307548928116 0.0805509959998426 0.9357990390224944 1.0 1.0 2 Q04721 1
Interaction between l1 and ankyrins 0.4748290863890775 0.074346148907622 0.9407349570914824 1.0 1.0 3 Q12955,Q13813 2
Tnfr1 induced proapoptotic signaling 0.4694004349176621 0.072118271108543 0.9425077858439486 1.0 1.0 2 Q13546 1
Defective ripk1 mediated regulated necrosis 0.4694004349176621 0.072118271108543 0.9425077858439486 1.0 1.0 2 Q13546 1
Regulation by c flip 0.4695463020509798 0.0678334000665043 0.9459182555779102 1.0 1.0 3 Q13546,P49327 2
Caspase activation via death receptors in the presence of ligand 0.4695463020509798 0.0678334000665043 0.9459182555779102 1.0 1.0 3 Q13546,P49327 2
Degradation of axin 0.2855145402250981 0.0625407512014657 0.95013221067176 1.0 1.0 36 P28072,P61289,P49721,O00231 4
Metabolism of polyamines 0.2841789166289184 0.0568713784939982 0.95464765405274 1.0 1.0 38 Q9UL46,P28072,P61289,P49721,O00231 5
Response of eif2ak1 hri to heme deficiency 0.4580484773151137 0.0547596319581784 0.9563299611508178 1.0 1.0 3 P05198,P08243 2
Platelet adhesion to exposed collagen 0.4311898105001531 0.0474558839007196 0.962149890241438 1.0 1.0 2 P05556 1
G protein mediated events 0.3093601418177187 0.0460619255678571 0.9632608927743816 1.0 1.0 11 P50148,P10644,P52292,P04899 4
The role of gtse1 in g2 m progression after g2 checkpoint 0.2754544554593248 0.0447444529428937 0.964311000834829 1.0 1.0 48 P28072,P61289,P04637,P49721,O00231 5
Enos activation 0.4471721566190282 0.0437381725746031 0.96511311100387 1.0 1.0 3 P07900,P35270 2
Sars cov 2 infection 0.2795121106570867 0.04362018578555 0.9652071610806808 1.0 1.0 23 P27824,Q16706,P46977,Q10472 4
Assembly of the hiv virion 0.4187635911773765 0.0420176909004713 0.9664845952715608 1.0 1.0 2 Q9H9H4 1
Lipophagy 0.3745725831520133 0.0383024520025299 0.9694465358072086 1.0 1.0 4 O60664,P54646,P54619 3
Pre notch processing in the endoplasmic reticulum 0.4013668841255016 0.0361019303614356 0.9712010831269982 1.0 1.0 2 Q04721 1
Inla mediated entry of listeria monocytogenes into host cells 0.4387818520820556 0.0360927546092042 0.9712083995497685 1.0 1.0 3 P35222,P12931 2
Disinhibition of snare formation 0.4381603480422725 0.0355551915099083 0.9716370377058324 1.0 1.0 3 Q12846,P05771 2
Role of lat2 ntal lab on calcium mobilization 0.4297700435052977 0.0286745859751384 0.9771241254848616 1.0 1.0 3 P07948,O00459 2
Notch4 intracellular domain regulates transcription 0.417961466749544 0.0201307130828886 0.983939099608764 1.0 1.0 3 Q04721,Q06330 2
Potential therapeutics for sars 0.2792838512627879 0.0194624489294948 0.9844721927783042 1.0 1.0 38 Q99720,P49354,P21964 3
Aryl hydrocarbon receptor signalling 0.3990055935363644 0.0089672805114698 0.9928452412158584 1.0 1.0 3 O00170,Q15185 2
Slc transporter disorders 0.2782723534907246 0.0078002325041688 0.993776378025604 1.0 1.0 33 Q9BTX1,O00400,Q8NFH5,Q9BW27,P53985,Q8N1F7,P35613,Q8NFH4,Q7Z3B4,Q99567 10
Regulation of beta cell development 0.3503263910475619 0.007665204806867 0.9938841113194792 1.0 1.0 4 Q13573,P31751,Q06330 3
Peroxisomal protein import 0.2798037903290018 0.0072389729895287 0.99422418566037 1.0 1.0 20 Q9BY49,P39210,O00116,O15254,O15228,O75381 6
Sars cov infections 0.2514760404251303 0.0070157458070542 0.9944022906585904 1.0 1.0 61 P49354,Q10472,P05023,Q99720,P46977,P21964 6
Signaling by retinoic acid 0.2960924447860999 0.0060219332595871 0.9951952214658332 1.0 1.0 12 Q8NBN7,P09622 2
Interleukin receptor shc signaling 0.3847110006215199 0.0023934361897134 0.9980903160402436 1.0 1.0 3 O00459,P62993 2
Pyroptosis 0.3190116084782071 0.0020192694318377 0.9983888571911276 1.0 1.0 6 Q9Y3E7,P04637 2
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