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Hedgehog off state 0.5989414496881669 3.023411144625085 0.00249942415862 0.9692249545716451 0.638067227709297 51 P49720,P61289,P28072,P49721,Q9Y496,P49841,Q9UL46,Q99436,P28070,O00231,P28074,Q13509,P20618,Q96J02,P60900,P10644,Q8NCM8 17
Interleukin 1 signaling 0.5956491448105256 2.950540977961575 0.003172179621673 0.9879599334760942 0.638067227709297 43 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P05067,P28070,O00231,O14920,P28074,P20618,P60900 13
Signaling by notch4 0.5823540146715762 2.8425878819226615 0.0044748892172201 0.9980472950659768 0.638067227709297 43 P49720,P61289,P28072,P49721,Q9Y6A5,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900,Q92542 13
Interleukin 1 family signaling 0.5661540615694333 2.8184084723024694 0.0048262368658777 0.9988049267162808 0.638067227709297 46 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P05067,P28070,O00231,O14920,P28074,P20618,P60900 13
Signaling by hedgehog 0.5628174168913884 2.639162816800338 0.008311105425232 0.9999909165528674 0.638067227709297 57 P49720,P61289,P28072,P49721,Q9Y496,P49841,Q9UL46,Q99436,P28070,O00231,P28074,Q13509,P20618,Q96J02,P60900,P10644,Q8NCM8 17
Degradation of beta catenin by the destruction complex 0.548434581720964 2.62529906129152 0.0086572890922982 0.999994411047825 0.638067227709297 49 P49720,P61289,P30153,Q16537,P28072,P49721,P49841,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 14
Fceri mediated nf kb activation 0.5535753513446223 2.6043530526708785 0.009204788339185 0.9999974081875096 0.638067227709297 43 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Hedgehog on state 0.5738579153964657 2.5233231777886425 0.0116251508463396 0.9999999136893152 0.638067227709297 41 P49720,P61289,P28072,P49721,Q9Y496,Q9UL46,Q99436,P28070,O00231,P28074,P20618,Q96J02,P60900 13
Regulation of runx2 expression and activity 0.5589515886158282 2.5224690746674256 0.0116534196348319 0.9999999170557704 0.638067227709297 42 P49720,P61289,P28072,P49721,P49841,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900,P42224 13
Antigen processing cross presentation 0.5396433209848672 2.5213250863459087 0.0116913784765753 0.9999999213707232 0.638067227709297 51 P49720,P61289,P04439,P28072,P49721,Q9UL46,Q99436,P10321,P28070,O00231,O14920,P28074,Q9UIQ6,P20618,P60900,Q03519 16
Regulation of hmox1 expression and activity 0.5298019100090458 2.5198430230439093 0.0117407181093218 0.9999999266458516 0.638067227709297 45 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P09601,P28070,O00231,P28074,P20618,P60900 12
Downstream signaling events of b cell receptor bcr 0.5563322986189964 2.500970614385584 0.0123853454654776 0.9999999704029806 0.638067227709297 42 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Tcr signaling 0.5277011421160648 2.473042430150818 0.0133968236354971 0.9999999928840894 0.638067227709297 47 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Orc1 removal from chromatin 0.5324343602844179 2.4723285233070316 0.013423609505385 0.9999999931478146 0.638067227709297 50 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,Q9Y619,P20618,P60900,Q14566 13
Negative regulation of notch4 signaling 0.5954822466979166 2.4699744027097714 0.0135122720533269 0.999999993953048 0.638067227709297 39 P49720,P61289,P28072,P49721,Q9Y6A5,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 12
Abc transporter disorders 0.53743321526137 2.4679123011891195 0.0135903611008212 0.9999999945835516 0.638067227709297 43 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900,Q9NP58 12
Cdt1 association with the cdc6 orc origin complex 0.5792962236715491 2.453083777246766 0.0141637347223519 0.999999997587523 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900,Q9Y619 12
Signaling by the b cell receptor bcr 0.5211700272976886 2.4440180004755643 0.0145247018283016 0.9999999985504668 0.638067227709297 45 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Peptide ligand binding receptors 0.8773260291367837 2.436212148221411 0.0148419770032952 0.9999999990738 0.638067227709297 7 P07602,P42892 2
Class a 1 rhodopsin like receptors 0.8773260291367837 2.436212148221411 0.0148419770032952 0.9999999990738 0.638067227709297 7 P07602,P42892 2
Degradation of gli1 by the proteasome 0.5760366107956387 2.427704828432226 0.0151947040948898 0.9999999994371764 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,Q96J02,P60900 12
Auf1 hnrnp d0 binds and destabilizes mrna 0.5669164513335596 2.356317949531685 0.0184571121841463 0.9999999999944306 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5162061793837659 2.343222340751483 0.0191179862711643 0.9999999999978176 0.638067227709297 49 P49720,P61289,P28072,P49721,Q9UJX4,Q9UL46,Q99436,P28070,Q16763,O00231,P28074,P20618,P60900 13
Clec7a dectin 1 signaling 0.5126544392816119 2.3400036545533704 0.0192835511954176 0.9999999999982744 0.638067227709297 47 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
The role of gtse1 in g2 m progression after g2 checkpoint 0.51301900331003 2.329028166847284 0.0198575735774677 0.9999999999992356 0.638067227709297 48 P49720,P61289,P28072,P49721,P04350,Q9UL46,Q99436,P28070,Q15691,O00231,P28074,Q13509,P20618,P25787,P60900,Q13885 16
Scf skp2 mediated degradation of p27 p21 0.562649677177365 2.3227279347658345 0.0201937726078218 0.9999999999995256 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Cyclin a cdk2 associated events at s phase entry 0.51874001303525 2.307310477801708 0.0210375178254549 0.9999999999998568 0.638067227709297 43 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P25787,P60900 12
Mapk6 mapk4 signaling 0.5072180095108962 2.2914622190972382 0.0219366945872241 0.99999999999996 0.638067227709297 47 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Metabolism of porphyrins 0.83284432913279 2.279682218344006 0.0226265426724545 0.999999999999985 0.638067227709297 9 P22830,P30519 2
Transcriptional regulation by runx3 0.5294534124665787 2.2773735651830695 0.0227639272993458 0.9999999999999876 0.638067227709297 42 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Hedgehog ligand biogenesis 0.5558316552880911 2.268797430901279 0.0232806472868243 0.999999999999994 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Defective cftr causes cystic fibrosis 0.5216868216175033 2.211741848966377 0.0269845071437733 1.0 0.638067227709297 42 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Gpcr ligand binding 0.810932823502302 2.2010120486752407 0.0277351708866417 1.0 0.638067227709297 10 P07602,P42892 2
Asymmetric localization of pcp proteins 0.5666441583866518 2.1523719063895395 0.0313680745408049 1.0 0.638067227709297 38 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
G1 s dna damage checkpoints 0.5535456066713036 2.148132242799892 0.0317032514810056 1.0 0.638067227709297 39 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Switching of origins to a post replicative state 0.510163663594068 2.1363350484564636 0.0326521140569451 1.0 0.638067227709297 60 P49720,P61289,P28072,P49721,Q9UJX4,Q9UL46,Q99436,P28070,Q16763,O00231,P28074,Q9Y619,P20618,P60900,Q14566 15
Cross presentation of soluble exogenous antigens endosomes 0.576536506688803 2.1347848007877364 0.0327785923745951 1.0 0.638067227709297 37 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Dectin 1 mediated noncanonical nf kb signaling 0.5353435619992511 2.104831322543992 0.035305993582861 1.0 0.638067227709297 40 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Transcriptional regulation by runx2 0.490788246756963 2.100320781120512 0.0357006324140414 1.0 0.638067227709297 50 P49720,P61289,P28072,P49721,P49841,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P25787,P60900,P42224 14
Degradation of dvl 0.571850169520971 2.1000123578930525 0.0357277540505884 1.0 0.638067227709297 37 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Tnfr2 non canonical nf kb pathway 0.5207873040382974 2.091498427255072 0.0364834072647275 1.0 0.638067227709297 41 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Regulation of ras by gaps 0.5584986560515949 2.090321995575193 0.0365888847184758 1.0 0.638067227709297 38 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Stabilization of p53 0.5566388699117024 2.076097770962841 0.0378849092975963 1.0 0.638067227709297 38 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7823046238932877 2.070950405968196 0.0383634309346536 1.0 0.638067227709297 10 Q7L5D6,P09601,P05067,P51648,O43765,P46379 6
Degradation of axin 0.5795609219000788 2.0703616740135464 0.0384184880700515 1.0 0.638067227709297 36 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Sphingolipid metabolism 0.6618020094146215 2.0642380883984472 0.038995147847225 1.0 0.638067227709297 28 Q16739,P07602,P10619,P04062,O95470,P06865,P17900,Q96G23,P06280,P16278 10
Metabolism of polyamines 0.554777228969709 2.0618381634950036 0.039223146335791 1.0 0.638067227709297 38 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Iron uptake and transport 0.7382101799470497 2.0567980522636 0.0397056555287573 1.0 0.638067227709297 18 P30519,P02786,Q9Y487,Q93050 4
C type lectin receptors clrs 0.4872542643222544 2.05385356509566 0.0399898667409472 1.0 0.638067227709297 51 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Sialic acid metabolism 0.8297592199791963 2.0537880652307776 0.0399962085670595 1.0 0.638067227709297 5 P16278,P10619 2
Apc c mediated degradation of cell cycle proteins 0.493181118373774 2.0376665262732905 0.0415832939714475 1.0 0.638067227709297 56 P49720,P61289,P28072,P49721,Q9UJX4,Q9UL46,Q99436,P28070,Q16763,O00231,P28074,P20618,P60900 13
Inflammasomes 0.8753360465646075 2.036932516510467 0.0416568050686763 1.0 0.638067227709297 4 P09601 1
Purinergic signaling in leishmaniasis infection 0.8753360465646075 2.036932516510467 0.0416568050686763 1.0 0.638067227709297 4 P09601 1
The nlrp3 inflammasome 0.8753360465646075 2.036932516510467 0.0416568050686763 1.0 0.638067227709297 4 P09601 1
Abc family proteins mediated transport 0.4899467044966423 2.036111485382768 0.0417391616875821 1.0 0.638067227709297 54 P28072,P49721,Q9UL46,P08183,O00231,P28074,Q9NUT2,P20618,P60900,Q9NP58,P40855 11
Glycosphingolipid metabolism 0.7387399282181638 2.02841003482874 0.0425184167834271 1.0 0.638067227709297 17 Q16739,P07602,P10619,P04062,P17900,P06280,P16278 7
Regulation of runx3 expression and activity 0.5617414999867891 2.0245723580924 0.0429112950128349 1.0 0.638067227709297 37 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Keratan sulfate keratin metabolism 0.7804540332355835 2.003629269474186 0.0451097880781772 1.0 0.6521112375286854 6 P06865,P16278,O43505 3
Rhoa gtpase cycle 0.4745020734409461 1.9939620166644356 0.0461562056289193 1.0 0.6521112375286854 47 Q92974,Q16513,P30519,Q13464,Q86VI3,O15173,O75116,P42166,Q9NSV4,Q5T8D3,Q96HY6,P11274,Q15904,P27105,P02786,Q9Y4F1,Q9UDY2,O15498 18
Heme degradation 0.9647793775747194 1.9904447734580384 0.0465419619107319 1.0 0.6521112375286854 3 P30519 1
Cellular response to hypoxia 0.54510047782733 1.9873759538207072 0.0468807503615158 1.0 0.6521112375286854 38 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Fc epsilon receptor fceri signaling 0.4803086889045436 1.9759260155422913 0.0481631572099652 1.0 0.6568132517555061 52 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,O14920,P28074,P20618,P60900 12
Cytoprotection by hmox1 0.4912074758549925 1.936855327329173 0.0527630305098032 1.0 0.6923903343314747 62 P28072,P49721,P30519,P09601,Q8N8Q8,O00231,P28074,P20618,P60900 9
Uch proteinases 0.4674626515203565 1.9287381737095977 0.0537633746406056 1.0 0.6975373691716427 47 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,Q8NB78,O00231,P28074,P20618,P60900 12
Cilium assembly 0.4914639693376781 1.9255692178758073 0.0541581853850017 1.0 0.6975373691716427 63 O95684,Q15051,Q9H6D7,Q13561,Q10713,P07437,Q15154,Q15691,Q92538,Q13509,Q13885,O00471,P30153,Q9Y496,O75935,A0AVF1,Q8NCM8,Q96CS2,O94927,P04350,P41208,Q8WYA0,Q9UPT5 23
Pcp ce pathway 0.4688253241447961 1.9125387741668345 0.0558071242195608 1.0 0.7057064526309915 49 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5197454444795631 1.8804925701734196 0.06004097802189 1.0 0.7302459143100114 39 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,Q96J02,P60900 12
Striated muscle contraction 0.8336442786069627 1.869963837138125 0.0614888398432433 1.0 0.7302459143100114 4 P08670,Q9NYL9,P67936 3
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7394564054343631 1.8575662389313805 0.0632306365856423 1.0 0.7302459143100114 9 P09601,Q16539,P05067,O14920,Q96J02 5
Mucopolysaccharidoses 0.8265293666872406 1.841226291497192 0.0655884040253083 1.0 0.7302459143100114 4 P16278,P54802 2
Recruitment of numa to mitotic centrosomes 0.5252916551318692 1.833173794320642 0.0667767296968067 1.0 0.7302459143100114 38 Q96CS2,P30153,O94927,P07437,O95684,Q15154,O75935,P04350,P41208,Q15691,Q13509,Q9H6D7,Q13561,Q13885 14
Signaling by ctnnb1 phospho site mutants 0.7396062845357636 1.8326685776158511 0.0668518729317244 1.0 0.7302459143100114 7 P49841,P30153,Q16537 3
Disassembly of the destruction complex and recruitment of axin to the membrane 0.7396062845357636 1.8326685776158511 0.0668518729317244 1.0 0.7302459143100114 7 P49841,P30153,Q16537 3
Beta catenin phosphorylation cascade 0.7396062845357636 1.8326685776158511 0.0668518729317244 1.0 0.7302459143100114 7 P49841,P30153,Q16537 3
Synthesis of pg 0.9193024557245512 1.8205536059862444 0.068674740609735 1.0 0.7375851287568661 3 Q8IV08 1
O linked glycosylation 0.7734544456332342 1.815393593540352 0.069463444908087 1.0 0.7375851287568661 5 Q8N4A0,O43505 2
O linked glycosylation of mucins 0.773454445633234 1.815393593540351 0.0694634449080873 1.0 0.7375851287568661 5 Q8N4A0,O43505 2
Sema4d induced cell migration and growth cone collapse 0.7215308027380303 1.7409351576487124 0.0816949451713338 1.0 0.7484773486269538 6 Q13464,O75116,Q7Z406,P35579,P35580 5
Phase i functionalization of compounds 0.6977665784241277 1.7261024378377756 0.0843289853454234 1.0 0.7484773486269538 13 O43169,P30837,P07099 3
Unblocking of nmda receptors glutamate binding and activation 0.7490943767329701 1.7106406764227962 0.0871474651556099 1.0 0.7484773486269538 5 Q12959,Q14168 2
Ras activation upon ca2 influx through nmda receptor 0.7490943767329701 1.7106406764227962 0.0871474651556099 1.0 0.7484773486269538 5 Q12959,Q14168 2
Negative regulation of nmda receptor mediated neuronal transmission 0.7490943767329701 1.7106406764227962 0.0871474651556099 1.0 0.7484773486269538 5 Q12959,Q14168 2
Mitotic g2 g2 m phases 0.5066211223840127 1.701484535868836 0.0888520392242149 1.0 0.7484773486269538 91 P28072,O95684,Q9UL46,O00231,Q9H6D7,P60900,Q13561,P49721,O75330,P07437,Q15154,P30154,Q15691,P28074,Q13509,P49720,P61289,P30153,O75935,Q99436,Q99640,P20618,P25787,Q96CS2,O94927,P41208,P28070 27
Long term potentiation 0.7124161927664365 1.69970547796182 0.0891863384393212 1.0 0.7484773486269538 6 Q12959,Q14168 2
Glycosaminoglycan metabolism 0.6789866673882052 1.6967240426617909 0.0897488449828178 1.0 0.7484773486269538 16 Q8N6G5,O75330,Q8NCH0,O94923,P54802,P06865,P34059,Q7LGA3,P16278,O43505 10
Pink1 prkn mediated mitophagy 0.7060182856592533 1.6899233283579227 0.0910426239207264 1.0 0.7484773486269538 8 Q9NS69,P21796 2
Transferrin endocytosis and recycling 0.696790425735416 1.6864331202978022 0.0917124066380423 1.0 0.7484773486269538 11 Q9Y487,Q93050 2
Keratan sulfate degradation 0.7428215249776837 1.6835223294398811 0.0922740204384022 1.0 0.7484773486269538 5 P06865,P16278 2
Nod1 2 signaling pathway 0.7428065395229639 1.6834574779297564 0.092286564403945 1.0 0.7484773486269538 5 Q96J02,Q16539 2
Dag and ip3 signaling 0.7063958007867315 1.6812716208885103 0.0927101675507304 1.0 0.7484773486269538 7 P10644 1
Diseases of carbohydrate metabolism 0.7011281480318806 1.6789290526178162 0.0931658716306937 1.0 0.7484773486269538 9 P10253,P16278,P54802 3
Beta catenin independent wnt signaling 0.4506482950033461 1.670625116176994 0.0947957483247425 1.0 0.7484773486269538 54 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P60900 11
Regulation of plk1 activity at g2 m transition 0.5152366658215245 1.669975126526975 0.0949242849481621 1.0 0.7484773486269538 37 Q96CS2,P30153,O94927,P07437,O95684,Q15154,O75935,P04350,P41208,Q15691,Q9H6D7,Q13561 12
Glycogen breakdown glycogenolysis 0.7017179801513872 1.6699568462603471 0.0949279019215709 1.0 0.7484773486269538 8 Q93100 1
Regulation of pten stability and activity 0.4591483253995016 1.6663901742359783 0.0956357265734053 1.0 0.7484773486269538 42 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P25787,P60900 12
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.738537381733091 1.6649692773409404 0.0959188853786727 1.0 0.7484773486269538 5 P05067 1
Signaling by notch 0.4546532408282979 1.6521249119650028 0.0985090894706939 1.0 0.7484773486269538 58 P49720,P61289,P28072,P49721,Q9Y6A5,Q9UL46,Q99436,P28070,O00231,P28074,P20618,Q96J02,P60900,Q92542,P42224 15
Vitamin d calciferol metabolism 0.8737954616101951 1.6485986424080443 0.0992298870522172 1.0 0.7484773486269538 3 Q99538,P04062 2
Regulation of localization of foxo transcription factors 0.7006649476732867 1.6463310977218533 0.0996956103399422 1.0 0.7484773486269538 6 P31946,P27348,Q9Y3B8 3
Activation of bad and translocation to mitochondria 0.6950181866240639 1.638782526113387 0.1012585596081674 1.0 0.7484773486269538 8 P31946,Q04917,Q9Y3B8,P27348 4
Anchoring of the basal body to the plasma membrane 0.5410136950507177 1.63866255847146 0.101283555835802 1.0 0.7484773486269538 34 Q96CS2,P30153,O94927,P07437,O95684,Q15154,O75935,P04350,P41208,Q15691,Q15051,Q9H6D7,Q13561 13
Aurka activation by tpx2 0.5410067826124314 1.6386126964202774 0.1012939464428188 1.0 0.7484773486269538 34 Q96CS2,P30153,O75330,O94927,O75935,O95684,P41208,Q9H6D7,Q13561 9
Endosomal vacuolar pathway 0.7754004675331186 1.6328532083431255 0.1024998732583539 1.0 0.7484773486269538 4 P10321,Q9UIQ6 2
Ion channel transport 0.5672985648437336 1.6315496712974595 0.10277438791355 1.0 0.7484773486269538 31 P51790,Q9HD20,Q9Y5K8,Q9C0H2,Q93050,P27105,P35670,Q13555,Q96PU5,Q9Y487 10
Platelet sensitization by ldl 0.6957839578461695 1.6240918273866802 0.1043562119381951 1.0 0.7521217140208777 6 P30153,Q16537,Q16539 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6903340926572757 1.616939968915851 0.1058912397106577 1.0 0.7592511053480665 8 Q9NR77,Q16850 2
Mapk family signaling cascades 0.4883714767164449 1.6083063624073952 0.1077680978991799 1.0 0.76482359274367 85 P28072,Q12959,Q9UL46,O00231,P60900,P49721,Q7Z569,Q14168,P31946,P28074,Q13555,O60725,P49720,P61289,P30153,Q99436,Q96P70,P07196,P20618,Q9Y4G8,Q16537,P28070 22
Activation of ampk downstream of nmdars 0.6834024067311602 1.5845471618343818 0.1130692581622692 1.0 0.7731641769099987 8 Q13885,Q13131,Q13509,P54619 4
Binding and uptake of ligands by scavenger receptors 0.6827978878268075 1.5817183087779214 0.113713891153429 1.0 0.7731641769099987 8 Q8WTV0 1
Protein localization 0.4688025288914282 1.581186056632634 0.1138355025268216 1.0 0.7731641769099987 73 Q8TB36,P51648,O60830,P21796,P46379,P40855,Q13505,P50402,Q10713,P34913,Q9NR77,O15228,O15254,Q9Y5J6,Q7L5D6,P09601,P05067,Q15388,O43765,O00116,Q9NX63,Q9NS69,P08574,Q5T8D3,Q9HAV7,Q9Y5J9,Q9Y512 27
Ca dependent events 0.6862859795490478 1.5807035563791971 0.1139458348429545 1.0 0.7731641769099987 6 P10644 1
Regulation of mrna stability by proteins that bind au rich elements 0.4461591186607371 1.5437681473887777 0.1226445104124986 1.0 0.8136817216416056 60 P49720,P61289,P28072,P49721,P39687,Q9NQT5,Q9UL46,Q99436,P31946,Q16539,P28070,O00231,P28074,P20618,P60900,Q01105 16
Ros and rns production in phagocytes 0.6715023705103143 1.538946612379846 0.1238173303332805 1.0 0.8136817216416056 9 Q93050 1
Chondroitin sulfate dermatan sulfate metabolism 0.705931439513884 1.5229792186675866 0.1277639046800389 1.0 0.8178367304392148 5 P06865,Q8N6G5 2
Heparan sulfate heparin hs gag metabolism 0.7056501356948881 1.521748694322054 0.1280720613668946 1.0 0.8178367304392148 5 P16278,Q7LGA3,P54802 3
Retrograde transport at the trans golgi network 0.6026132840014655 1.5213468047785177 0.1281728305073679 1.0 0.8178367304392148 24 Q9Y2V7,O43493,Q99747,P11717,P20645,Q5VZE5,Q7Z6M1,O60499,Q5VIR6 9
Copi dependent golgi to er retrograde traffic 0.423265517005451 1.5096673551825126 0.1311283251116985 1.0 0.8264609680154804 47 P33176,O00139,P24390,Q9Y496,Q8NI77,Q9NSK0,Q99747,A2RRP1,P52732,Q92538,Q13509,Q9P2W9,Q6NUQ1,Q13885 14
Recruitment of mitotic centrosome proteins and complexes 0.5320948648741713 1.5089683046441371 0.1313068827688146 1.0 0.8264609680154804 33 Q96CS2,P30153,O94927,P07437,O95684,Q15154,O75935,P04350,P41208,Q15691,Q9H6D7,Q13561 12
Carboxyterminal post translational modifications of tubulin 0.6668978884836738 1.4917027857187304 0.1357770785127283 1.0 0.839426975809755 6 Q13509,Q14166,Q13885 3
Cellular response to chemical stress 0.4564452670629448 1.4648621199406977 0.1429585394658288 1.0 0.848566481935392 73 O14548,Q8TED1,P28072,P49721,Q9UL46,P30519,P09601,P28070,Q8N8Q8,O00231,P28074,Q04656,P20618,P60900 14
Mitochondrial protein import 0.5246679534004303 1.4559693321094809 0.1454010976489879 1.0 0.8498022135703452 33 Q9Y5J6,Q10713,Q9Y512,Q9NS69,Q15388,P08574,O60830,P21796,Q9Y5J9,Q9NX63,Q13505 11
Ub specific processing proteases 0.4538296680796598 1.4533873147548362 0.1461162465240106 1.0 0.8504087820707065 72 P28072,P49721,Q9UL46,Q96FW1,Q15388,O00231,P28074,P21796,P20618,P60900,P45880 11
Copi mediated anterograde transport 0.4243964294981285 1.4338990584910531 0.1516010705945465 1.0 0.8649433072640139 53 Q9Y2V7,O95249,P24390,O75935,P83436,Q08379,Q99747,Q12955,Q13885,Q92538,Q13509,Q14789,Q13561,Q13813,O15498,Q14746 16
Fgfr1 mutant receptor activation 0.6453745805250082 1.4246622374162996 0.1542548599291824 1.0 0.8649433072640139 10 O95684,Q92614 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6485389315876117 1.406949541357851 0.1594423516734022 1.0 0.8800964729273911 6 P10321,P04439,Q5KU26,P78310 4
Insulin receptor recycling 0.6375841388294972 1.386884889403902 0.1654768662107699 1.0 0.9043249965095892 10 Q93050 1
Signaling by cytosolic fgfr1 fusion mutants 0.6412322381979845 1.3858848074571064 0.1657820805966536 1.0 0.9043249965095892 8 O95684 1
Assembly and cell surface presentation of nmda receptors 0.6333054826433308 1.3773549677255752 0.1684025283943051 1.0 0.9078678823937256 11 Q12959,Q13555,Q14168 3
Transport of inorganic cations anions and amino acids oligopeptides 0.6346685618759451 1.3547540907857574 0.1754959179357862 1.0 0.9149114504680856 8 Q70HW3,P30825,P08195 3
Raf activation 0.6277299668854727 1.3389941442236395 0.180572579237602 1.0 0.9200602846868297 10 P30153,Q16537,Q7Z569,P31946,Q13555 5
Keratinization 0.6326376259619071 1.3332309743761008 0.1824560175434095 1.0 0.9228957105559372 6 P04632 1
Formation of the cornified envelope 0.6326376259619071 1.3332309743761008 0.1824560175434095 1.0 0.9228957105559372 6 P04632 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6278191232800594 1.3300685372775 0.1834956907065816 1.0 0.9229880654585604 9 P49366,O60725 2
Intra golgi traffic 0.6073324978343617 1.32306839052644 0.1858126353813411 1.0 0.9239979508592734 16 Q9Y2V7,O95249,Q99747,O00461,Q16706,Q8TBA6,Q14746 7
Activation of ppargc1a pgc 1alpha by phosphorylation 0.7833507138882181 1.30344692092529 0.1924222264799737 1.0 0.9239979508592734 3 P54619 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.6200153045864968 1.2925168360288672 0.196178219289336 1.0 0.9239979508592734 9 P31946,P27348,Q04917,Q9Y3B8 4
Signaling by fgfr1 in disease 0.6157124020747181 1.2906627549413432 0.1968206449615852 1.0 0.9239979508592734 11 O95684,Q92614 2
G alpha i signalling events 0.5580857055979127 1.2903715768249313 0.1969216758742298 1.0 0.9239979508592734 25 P10644,P07602,P05067 3
Constitutive signaling by akt1 e17k in cancer 0.7789626187552969 1.2866801219185209 0.1982058043431465 1.0 0.9239979508592734 3 P49841 1
Mastl facilitates mitotic progression 0.6916528985141928 1.286559219281954 0.198247965490772 1.0 0.9239979508592734 4 P30153,P30154 2
Sema4d in semaphorin signaling 0.621401563819333 1.285653849150007 0.1985638944913677 1.0 0.9239979508592734 7 Q13464,O75116,Q7Z406,P35579,P35580 5
Dna replication pre initiation 0.4191542446605755 1.2845307459971966 0.1989563127982221 1.0 0.9239979508592734 60 P28072,P49721,Q9UL46,O00231,P15927,P28074,Q9Y619,P20618,P60900,Q14566 10
Hs gag degradation 0.96146674953387 1.276936573096587 0.201624640806632 1.0 0.9239979508592734 2 P54802 1
Arms mediated activation 0.7755898193351559 1.2737969054189688 0.2027354021821379 1.0 0.9239979508592734 3 P31946 1
Sphingolipid de novo biosynthesis 0.6119941269074168 1.272300801844437 0.2032662638123203 1.0 0.9239979508592734 11 Q06136,P51648,Q9Y5P4,P22059,Q96G23,O95470 6
Tcf dependent signaling in response to wnt 0.4183355468734666 1.262725001409665 0.2066880257843488 1.0 0.9349235339297852 61 P49720,P61289,P30153,Q16537,P28072,P49721,P49841,Q9UL46,Q99436,P28070,O00231,P28074,P20618,P25787,P60900 15
Intra golgi and retrograde golgi to er traffic 0.4642603519035281 1.258437825917361 0.2082334593112762 1.0 0.9349235339297852 95 Q9Y2V7,P33176,Q13561,Q16706,Q5VIR6,O00461,O15498,O95249,P24390,P83436,O43493,A2RRP1,Q8N2H4,Q92538,P11717,P20645,Q13509,Q8TD16,Q9P2W9,Q14746,Q9Y496,Q8NI77,O75935,Q5VZE5,Q8TBA6,Q6NUQ1,O00139,Q9NSK0,Q99747,P52732,Q7Z6M1,O60499,Q10472 33
Biological oxidations 0.4232754770061755 1.246409477885651 0.2126141034304434 1.0 0.9349235339297852 41 Q16850,O43169,P07099,Q9NX62,P30837 5
Arachidonic acid metabolism 0.6116450520667842 1.2452390995621878 0.2130438741811335 1.0 0.9349235339297852 8 P34913,Q15165,Q8N8N7 3
Transport of bile salts and organic acids metal ions and amine compounds 0.7659560259765658 1.2370239777316063 0.2160781809934402 1.0 0.9427437130334652 3 Q15043 1
Factors involved in megakaryocyte development and platelet production 0.3934931304879917 1.2335369510056813 0.217375499482038 1.0 0.9427437130334652 46 Q9H4M9,P33176,O00139,Q9Y496,Q8NI77,Q8IWA4,Q96N67,Q9NSK0,O43572,P52732,Q13509,P10644,O95140,Q13885 14
Autophagy 0.4005122890374266 1.2300507519807495 0.2186781003078997 1.0 0.9427437130334652 51 P08670,P13473,Q9NS69,P21796,Q13509,Q9H9H4,P54619 7
Intraflagellar transport 0.5986621319085863 1.229522997290215 0.2188757808589518 1.0 0.9427437130334652 13 Q9Y496,P04350,A0AVF1,Q13509,Q8NCM8,Q13885 6
Antigen processing ubiquitination proteasome degradation 0.4550456820804618 1.2207418095974607 0.2221837922640024 1.0 0.9483664828304114 91 P28072,Q9UL46,O00231,Q14139,Q96J02,P60900,Q96PU5,P52888,P55786,P49721,P28074,P49720,P61289,Q8IWV8,Q99436,Q8TDB6,Q16763,Q05086,Q9UIQ6,P20618,Q9BSL1,Q9UJX4,P28070,Q6UWE0 24
Diseases associated with glycosylation precursor biosynthesis 0.6058850745429954 1.21778287142828 0.2233064950440808 1.0 0.9483664828304114 8 P16278,P10619 2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5801338910300456 1.217771612756518 0.2233107746314535 1.0 0.9483664828304114 18 Q9BTY2,Q02818,O43493,P05067,Q07065,O43852,P11047 7
Transport of small molecules 0.5326216593409638 1.2122625030564047 0.2254119125318694 1.0 0.9483664828304114 157 P28072,Q93050,P30519,Q9UL46,Q15043,O00231,O15118,P21796,P30825,P61916,Q6P1M0,P60900,Q8WTV0,Q96PU5,Q9BPX6,Q9Y487,P40855,P49721,Q10713,P28074,P02786,Q13555,P45880,Q9HD20,Q9C0H2,Q9UBX3,P09601,P08183,Q70HW3,P53985,P20618,P10644,P35670,Q9NUT2,Q9NP58,Q9Y5K8,P08195 37
Dna damage reversal 0.6731180775609251 1.2096458783659898 0.226414805664453 1.0 0.9483664828304114 4 Q9H1I8,Q6P6C2 2
Cdc42 gtpase cycle 0.5054867935259172 1.208250361039362 0.2269509757184713 1.0 0.9483664828304114 31 Q86VI3,Q9UQB8,P42166,P02786,P27105,Q96N67 6
Cargo recognition for clathrin mediated endocytosis 0.4818937886714837 1.2051317579864038 0.2281524415501667 1.0 0.9483664828304114 34 O43493,P01130,P11717,Q9BT78,P02786,P20645,Q9UBC2,P61201,Q14108 9
Transport of connexons to the plasma membrane 0.6327539730311054 1.200864053256686 0.2298039402109857 1.0 0.9485379253219024 5 Q13509,Q13885 2
Gap junction assembly 0.6327539730311054 1.200864053256686 0.2298039402109857 1.0 0.9485379253219024 5 Q13509,Q13885 2
Pp2a mediated dephosphorylation of key metabolic factors 0.754554990351898 1.1935707279480994 0.232645930055138 1.0 0.9574274813807604 3 P30153 1
Nuclear signaling by erbb4 0.6192409037065825 1.141228453634553 0.2537748665302859 1.0 0.967628820913284 5 P61201,Q92542 2
Transport to the golgi and subsequent modification 0.4240318218687051 1.1159130437085856 0.2644593579008023 1.0 0.9678753081735672 76 Q9Y2V7,Q08379,Q16706,Q13561,O15498,O95249,P24390,P04066,Q12955,Q96PC5,Q13509,Q14746,Q9Y6Y8,O75935,Q14789,P53634,Q99747,Q9Y296,O00743 19
Plasma lipoprotein clearance 0.5703259088466115 1.1114547203195153 0.2663726698121795 1.0 0.9678753081735672 15 Q8WTV0,O15118 2
Trans golgi network vesicle budding 0.4531678466933358 1.111342076898138 0.2664211343675498 1.0 0.9678753081735672 36 O75976,Q14677,O43493,P05067,Q01968,Q10567,P11717,P02786,P20645,Q92538,Q14789,Q9Y5X1 12
Mitochondrial calcium ion transport 0.5668143591574045 1.1084792782210604 0.2676548834588614 1.0 0.9694624758602908 16 P45880,P21796,Q10713 3
Interaction between l1 and ankyrins 0.7317376437674757 1.10692318450462 0.2683271410540704 1.0 0.9694624758602908 3 Q12955,Q13813 2
Cyclin a b1 b2 associated events during g2 m transition 0.5793527283758916 1.1027830028228895 0.2701214111313286 1.0 0.9696665187979868 10 P30153,P30154,Q99640 3
Selective autophagy 0.4826587224419224 1.0990075985061083 0.2717647515689629 1.0 0.9696665187979868 32 P08670,Q9NS69,P21796,Q13509,P54619 5
Slc mediated transmembrane transport 0.5537097299322721 1.0934914844105976 0.2741780658395261 1.0 0.9696665187979868 19 Q15043,Q70HW3,P30825,P53985,Q6P1M0,P08195 6
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6441199472275401 1.0896480013270535 0.2758682297656707 1.0 0.9696665187979868 4 P30153 1
Signaling by wnt in cancer 0.5753597136389653 1.0770001961783646 0.2814801780498248 1.0 0.980266035170637 9 P49841,P30153,Q16537 3
Disorders of transmembrane transporters 0.419819543743455 1.0753586508717354 0.2822141867830081 1.0 0.980266035170637 76 P28072,Q8N1F7,Q9UL46,P12270,O00231,Q6P1M0,P60900,P49721,P28074,Q8NFH5,P49720,P61289,Q99436,O15504,P53985,P20618,Q9NP58,Q9BTX1,P28070,P08195 20
Mhc class ii antigen presentation 0.3888203100522526 1.0582106675777518 0.2899594089474178 1.0 0.9954804622529262 55 P33176,Q99538,Q9Y496,O00139,Q8NI77,O75935,P53634,P10619,Q9NSK0,Q10567,P52732,P50570,Q13509,Q13561,Q9BXW6,Q13885 16
Negative regulation of mapk pathway 0.5688673692410406 1.0515209462113106 0.2930193943523234 1.0 0.9982663588212768 10 P30153,Q16537,Q7Z569,P30154,P31946 5
Ecm proteoglycans 0.6343418770252255 1.0493636437429763 0.2940107843761534 1.0 0.9982663588212768 4 P05067 1
G2 m checkpoints 0.4264465190874925 1.0488634213757555 0.2942409828301391 1.0 0.9982663588212768 83 P28072,Q9UL46,Q04917,O00231,P38398,P60900,P49721,Q9UQ84,P31946,P27348,P28074,P49720,P61289,P40937,Q9Y3B8,Q99436,Q99640,P20618,Q14566,Q9Y619,P28070,P15927 22
Nephrin family interactions 0.5686390762096066 1.040108912242501 0.2982893035522265 1.0 1.0 8 Q01082,Q9Y5K6,O43707,P12814,Q13813 5
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5672711606960923 1.0335905696057524 0.3013276098899355 1.0 1.0 8 Q9UQ84 1
Resolution of d loop structures 0.5672711606960923 1.0335905696057524 0.3013276098899355 1.0 1.0 8 Q9UQ84 1
Darpp 32 events 0.5653293827341518 1.0285952097405706 0.3036699298965872 1.0 1.0 9 P10644,P30153 2
Bile acid and bile salt metabolism 0.5620668009227613 1.006067260304242 0.3143832164060447 1.0 1.0 7 Q9BXW6,Q9BZF3,Q96SU4 3
Synthesis of bile acids and bile salts 0.5620668009227613 1.006067260304242 0.3143832164060447 1.0 1.0 7 Q9BXW6,Q9BZF3,Q96SU4 3
Tryptophan catabolism 0.886264760720946 1.0039617355194912 0.3153970576397844 1.0 1.0 2 P08195 1
Caspase mediated cleavage of cytoskeletal proteins 0.5878148632375344 1.0029938967303766 0.3158638060223651 1.0 1.0 5 P08670,Q13813 2
Chaperone mediated autophagy 0.5595182990094679 0.9940847722546392 0.3201815982360823 1.0 1.0 7 P08670 1
Signaling by flt3 fusion proteins 0.5850014621815827 0.9906727575978824 0.3218453975969395 1.0 1.0 5 Q92614 1
G2 m dna replication checkpoint 0.6997399392946149 0.986534998679526 0.3238706495912531 1.0 1.0 3 Q99640 1
Rac2 gtpase cycle 0.4440026691510386 0.9783356113078214 0.3279083625254233 1.0 1.0 35 Q9Y512,O15173,Q5T2T1,P42166,P02786,Q86XL3,Q13505 7
G protein mediated events 0.5511475000757227 0.9711960047268302 0.3314506830414994 1.0 1.0 11 P10644,Q13555,P52292,P63096 4
Hs gag biosynthesis 0.8766314481044046 0.9697123174505784 0.3321899090274476 1.0 1.0 2 Q7LGA3 1
Ion transport by p type atpases 0.5482723465682318 0.9644300766116478 0.3348303491886382 1.0 1.0 12 P35670,Q13555,Q9HD20 3
Leishmania infection 0.4178091064720682 0.9605953286337322 0.3367556783908667 1.0 1.0 38 P09601,P05067,Q9UQB8 3
Reactions specific to the complex n glycan synthesis pathway 0.8732131758856332 0.9576126929022488 0.338258096299135 1.0 1.0 2 P04066 1
N glycan antennae elongation in the medial trans golgi 0.8732131758856332 0.9576126929022488 0.338258096299135 1.0 1.0 2 P04066 1
Notch3 activation and transmission of signal to the nucleus 0.8719701678060789 0.9532201017471512 0.3404785634996683 1.0 1.0 2 Q9Y6A5 1
Depolymerisation of the nuclear lamina 0.5495189161049266 0.9524566720103737 0.3408654298332054 1.0 1.0 9 P50402,P02545,P05771,P42166 4
Plasma lipoprotein assembly remodeling and clearance 0.5270315009568545 0.945272552969803 0.3445197471960421 1.0 1.0 19 Q8WTV0,O15118 2
E2f enabled inhibition of pre replication complex formation 0.5484945537412222 0.9416317429925554 0.3463812121493115 1.0 1.0 6 Q9Y619,P06493 2
Signaling by notch3 0.5476406396136957 0.9376780281864496 0.348409898596604 1.0 1.0 6 Q9Y6A5,Q92542 2
Signaling by insulin receptor 0.5340841495481353 0.934898812070543 0.3498404493610234 1.0 1.0 16 Q93050 1
Mitophagy 0.5386321543546948 0.9245176407313838 0.3552168711735293 1.0 1.0 13 Q9NS69,P21796 2
Rho gtpases activate rocks 0.5428591005707115 0.9204763196511312 0.3573239021687575 1.0 1.0 9 Q13464,O75116,Q7Z406,P35579,P35580 5
Er to golgi anterograde transport 0.3988983109393626 0.8992703269940359 0.3685086886380757 1.0 1.0 74 Q9Y2V7,O95249,Q9Y6Y8,P24390,P53634,O75935,Q08379,Q99747,Q12955,Q96PC5,Q9Y296,Q13509,O00743,Q14789,Q13561,O15498,Q14746 17
Golgi to er retrograde transport 0.3902372996685429 0.8941318333414043 0.3712513588919248 1.0 1.0 68 P33176,O00139,P24390,Q9Y496,Q8TD16,Q8NI77,O75935,Q10472,Q9NSK0,Q99747,A2RRP1,P52732,Q92538,Q13509,Q13561,Q9P2W9,Q6NUQ1 17
Interconversion of nucleotide di and triphosphates 0.5150312789857354 0.8787924279861672 0.3795138326054341 1.0 1.0 19 Q9H773 1
Rac3 gtpase cycle 0.4441220848964607 0.8715267102351428 0.3834666282417842 1.0 1.0 33 Q9UQB8,O15173 2
Epha mediated growth cone collapse 0.5289667008282439 0.8540176284988994 0.3930952218906463 1.0 1.0 9 Q15375,Q13464,O75116,Q7Z406,P35579,P35580 6
Flt3 signaling in disease 0.5294435471792323 0.853741056622053 0.393248480142685 1.0 1.0 6 Q92614 1
Adenylate cyclase inhibitory pathway 0.6580665216039665 0.832973627392055 0.4048596030757165 1.0 1.0 3 P04899,P63096 2
Synthesis of dna 0.4043103578096034 0.8237871567337007 0.4100605064071601 1.0 1.0 84 P28072,Q9UL46,O00231,P60900,P49721,P28074,P49005,Q9BRT9,P49720,P61289,P40937,Q99436,Q16763,P20618,Q14566,Q9Y619,Q9UJX4,P28070,P15927 19
Activated notch1 transmits signal to the nucleus 0.8337476693598522 0.8203246230303813 0.4120310730702412 1.0 1.0 2 Q92542 1
Stimuli sensing channels 0.5198054028141674 0.8131719380979011 0.4161194860163335 1.0 1.0 10 Q96PU5,Q9C0H2,P27105 3
Sensory processing of sound by outer hair cells of the cochlea 0.5161615680999588 0.8046457258345021 0.4210241474463494 1.0 1.0 12 Q13813,P23634,P35579,Q00013,Q6IBS0 5
Map3k8 tpl2 dependent mapk1 3 activation 0.6488093421117973 0.7995579786335654 0.4239669421563996 1.0 1.0 3 O14920 1
Apoptotic cleavage of cellular proteins 0.4956847838241317 0.7889669925392401 0.43013129861537 1.0 1.0 20 P08670,P02545,Q13464,Q15149,Q16625,Q9P289,Q9UDY2,Q13813 8
Kinesins 0.4952086382996535 0.7863074028948032 0.4316874165241555 1.0 1.0 20 P33176,O00139,Q9Y496,Q8NI77,Q9NSK0,P52732,Q13509,Q13885 8
Diseases of glycosylation 0.4978162330496662 0.7839029361832994 0.4330970667808416 1.0 1.0 19 P10619,Q9Y223,P06865,P16278,O43505 5
Cd28 dependent pi3k akt signaling 0.6435207813380281 0.7806067206204017 0.4350338378220657 1.0 1.0 3 P31751 1
Amino acid transport across the plasma membrane 0.6418943448858437 0.7747999372865687 0.4384578863556516 1.0 1.0 3 P30825 1
Transport and synthesis of paps 0.819453076444999 0.7718972779511019 0.4401752696652967 1.0 1.0 2 O43252 1
Regulation of tp53 expression and degradation 0.5110722024040714 0.7691047812816385 0.4418311100351495 1.0 1.0 9 Q93009,P30154,P30153,P31751 4
Signaling by fgfr in disease 0.4920448409960578 0.768652873468802 0.4420994083625675 1.0 1.0 20 O95684,Q92614,P35269 3
Class i peroxisomal membrane protein import 0.5066562984909766 0.7578283188785944 0.4485537668175441 1.0 1.0 12 Q8TB36,Q9NR77,P51648,Q5T8D3,P40855 5
Cd163 mediating an anti inflammatory response 0.8135487880671246 0.7521322053677508 0.4519715582757206 1.0 1.0 2 Q16539 1
Ire1alpha activates chaperones 0.4812245054535318 0.7451482865333977 0.4561820811660853 1.0 1.0 22 P02545,P43307,O76024,O95070,O14773,Q9NWM8 6
Rhob gtpase cycle 0.4678986417320845 0.7358714354440798 0.4618089423340199 1.0 1.0 25 Q92974,Q13464,Q86VI3,O75116,Q9NSV4,P11274,P02786,P27105,Q9UDY2,Q16513 10
Lysosome vesicle biogenesis 0.497859909301497 0.734804137228592 0.4624587870900458 1.0 1.0 15 P05067,P20645 2
Initiation of nuclear envelope ne reformation 0.4972130212613043 0.7314946698720267 0.4644770590285647 1.0 1.0 15 P30153,P02545,Q86XL3,P42166 4
Neddylation 0.3770771759879491 0.7268040440122877 0.4673460054010541 1.0 1.0 71 Q9NX08,P28072,P49721,Q9Y5A7,P61201,Q9UL46,P28070,O00231,P28074,P20618,P60900 11
Hur elavl1 binds and stabilizes mrna 0.5232858729530493 0.725120844173084 0.4683778979108246 1.0 1.0 5 Q01105 1
Akt phosphorylates targets in the cytosol 0.8023617153511524 0.715096118346676 0.474549652321621 1.0 1.0 2 P49841 1
Mismatch repair 0.4956028823744385 0.7001024283810185 0.4838633394097047 1.0 1.0 11 P15927,Q9UQ84 2
Deubiquitination 0.4036574586725492 0.6953196420479255 0.4868550074517079 1.0 1.0 94 P28072,P49721,P54725,Q9UL46,Q96FW1,Q8NB78,O00231,Q15388,P28074,P38398,P21796,P20618,P60900,P45880 14
Rnd2 gtpase cycle 0.4815738908131382 0.6951887474592624 0.4869370232410692 1.0 1.0 19 Q08378,O43396,Q9ULK5,Q03001,P51648,Q07065,P02786,Q9Y266 8
Ctla4 inhibitory signaling 0.4916083142972777 0.6782858884605532 0.4975904442742209 1.0 1.0 8 P30153,Q16537,P31751 3
G alpha z signalling events 0.4903944003247248 0.676783712173794 0.49854319384298 1.0 1.0 6 Q9UBI6,P04899,P05771,P63096 4
Type i hemidesmosome assembly 0.7877563704164111 0.6676262016473385 0.5043722281532179 1.0 1.0 2 Q03001 1
Assembly of collagen fibrils and other multimeric structures 0.7877563704164111 0.6676262016473385 0.5043722281532179 1.0 1.0 2 Q03001 1
Rac1 gtpase cycle 0.3331557326655594 0.6612335191337374 0.5084625683962463 1.0 1.0 44 Q9UQB8,Q86VI3,Q5T2T1,P42166,Q96F07,P02786,O15498,Q96N67 8
Golgi associated vesicle biogenesis 0.4364909331081825 0.6552472153505173 0.512308599627993 1.0 1.0 29 O75976,Q14677,O43493,Q01968,Q10567,P11717,P02786,Q14789,Q9Y5X1 9
Basigin interactions 0.4851519018056394 0.6534986434011157 0.5134348637119608 1.0 1.0 6 P53985 1
Metabolism of cofactors 0.4845490578129823 0.6508300026774267 0.5151562304238504 1.0 1.0 6 O75208,P00374 2
Translocation of slc2a4 glut4 to the plasma membrane 0.3939148865630307 0.6463083912412195 0.5180796546076718 1.0 1.0 36 O00471,Q9Y496,Q9Y3B8,P31946,Q04917,P27348,Q13885,Q9UIQ6,Q13509,Q9UPT5,P35579,P31751,P54619 13
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.779987569919182 0.6428179506659764 0.5203422339796668 1.0 1.0 2 Q13555 1
Camk iv mediated phosphorylation of creb 0.779987569919182 0.6428179506659764 0.5203422339796668 1.0 1.0 2 Q13555 1
Small interfering rna sirna biogenesis 0.6012013088386603 0.6333641555990432 0.5264958667321689 1.0 1.0 3 Q15631 1
Separation of sister chromatids 0.4114064333335441 0.6284664838866014 0.5296983960417903 1.0 1.0 106 P28072,Q9UL46,Q9BZD4,O00231,O75122,Q8WVM7,P60900,O14777,P49721,P30154,Q15691,Q96BD8,P28074,Q7Z5K2,Q8N3U4,Q13509,Q13885,P49720,P61289,P30153,Q8NI77,Q6IPU0,Q99436,Q16763,P57740,P20618,P25787,Q16537,O00139,Q9UJX4,P28070 31
Class i mhc mediated antigen processing presentation 0.4221218736084884 0.6276376854744872 0.5302413154422312 1.0 1.0 115 P28072,Q9UL46,O00231,Q14139,Q96J02,P60900,Q96PU5,P52888,P55786,P49721,P28074,P49720,P61289,Q6P179,Q8IWV8,Q9NZ08,Q99436,P10321,Q8TDB6,Q16763,Q05086,O14920,Q9UIQ6,P20618,Q9BSL1,P04439,Q9UJX4,P28070,Q03519,Q6UWE0 30
Energy dependent regulation of mtor by lkb1 ampk 0.4802463400242676 0.6266147634176814 0.5309117885153114 1.0 1.0 8 Q13131,P54619 2
Opioid signalling 0.4678600935139023 0.6211719083580585 0.5344865204731568 1.0 1.0 19 P30153,P52292,P63096,P30154,P10644,Q13555 6
Ubiquinol biosynthesis 0.7719080174020931 0.6173664862228356 0.5369930221667674 1.0 1.0 2 O75208 1
Tnf signaling 0.4740820298281274 0.601334767695687 0.5476170370030919 1.0 1.0 7 Q8TCT8,O95429 2
Activation of bh3 only proteins 0.4728670131554953 0.5943982580935299 0.5522457732609409 1.0 1.0 12 P31946,P27348,Q04917,Q9Y3B8 4
Rnd1 gtpase cycle 0.4668885831005222 0.5939887226678178 0.5525196557384167 1.0 1.0 17 P31948,O43396,O75976,Q8TAA9,Q9ULK5,Q03001,P51648,P02786 8
Budding and maturation of hiv virion 0.4723437537590081 0.5919144692846815 0.5539078641553523 1.0 1.0 12 Q96PU5 1
Glutathione synthesis and recycling 0.4699076645383309 0.5866409445604823 0.557444877737193 1.0 1.0 6 Q9UJ14 1
Cell surface interactions at the vascular wall 0.4649726876961251 0.5841365764113201 0.559128428213262 1.0 1.0 17 Q92896,P14174,P53985 3
Rhoc gtpase cycle 0.4100769089468205 0.5840036627770511 0.559217847754955 1.0 1.0 32 Q13464,Q86VI3,O75116,P42166,Q9NSV4,Q5T8D3,P11274,P02786,P27105,Q9UDY2,Q16513 11
Activation of nmda receptors and postsynaptic events 0.4488013644679742 0.5783304758111947 0.563041022692814 1.0 1.0 23 Q12959,Q14168,P10644,Q13555,P54619 5
Oncogenic mapk signaling 0.4408401305294737 0.5727531200309568 0.5668118649600442 1.0 1.0 25 P02545,Q9NRY5,Q7Z569 3
Mitotic prometaphase 0.3912799848292373 0.566660764833443 0.5709446823103503 1.0 1.0 95 O95684,Q9BZD4,O75122,Q8WVM7,Q9H6D7,Q13561,O14777,P07437,Q15154,P30154,Q15691,Q96BD8,Q7Z5K2,Q8N3U4,Q13509,Q13885,P30153,Q8NI77,O75935,Q6IPU0,P57740,Q96CS2,Q16537,O00139,O94927,P41208,P04350 27
Amyloid fiber formation 0.4820092946267031 0.556457125048201 0.577898396629871 1.0 1.0 5 P05067 1
Urea cycle 0.752019888129248 0.5563580613979199 0.5779661027460252 1.0 1.0 2 Q9Y619 1
Antimicrobial peptides 0.576277896027219 0.5512145858295244 0.5814865824806694 1.0 1.0 3 Q04656 1
Collagen biosynthesis and modifying enzymes 0.460677487298248 0.5359148105017821 0.5920174281033859 1.0 1.0 11 O15460,P13674,Q32P28 3
Platelet homeostasis 0.4595226965976574 0.5316236819976339 0.5949866592541795 1.0 1.0 12 P23634,Q16537,Q16539,P30153 4
Interferon gamma signaling 0.4588602815050008 0.5275845734863313 0.5977877023843519 1.0 1.0 11 Q13555,P10321,P04439 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4558137294188153 0.5181260621124028 0.6043703175484119 1.0 1.0 8 Q12959,Q14168 2
Mitotic g1 phase and g1 s transition 0.3639133427064354 0.5122366909560286 0.608485367149195 1.0 1.0 78 P49720,P61289,P30153,P49721,P28072,Q9UL46,P28070,Q99436,P00374,O00231,P15927,P28074,Q14566,P20618,P25787,P60900,P31350,Q9Y619 18
Nef mediated downregulation of mhc class i complex cell surface expression 0.4678694120127156 0.5013137330867516 0.6161503417283094 1.0 1.0 5 Q10567 1
Abortive elongation of hiv 1 transcript in the absence of tat 0.4510329974487692 0.4966984845700617 0.6194016912538578 1.0 1.0 14 Q8IXH7,P35269 2
Response of eif2ak1 hri to heme deficiency 0.5564190239353487 0.4888087786252238 0.6249770824107339 1.0 1.0 3 P08243,P20042 2
Response to elevated platelet cytosolic ca2 0.3838529172917957 0.4777462657008193 0.6328308105094724 1.0 1.0 34 Q8NBX0,P07602,Q08380,P05067,O43852 5
Diseases of dna repair 0.4477021620492348 0.4771256997505149 0.6332726152234689 1.0 1.0 12 P38398,Q9UQ84 2
Signaling by braf and raf1 fusions 0.4369849753217723 0.4691999048304706 0.6389267535108183 1.0 1.0 20 P02545,Q9NRY5 2
Signaling by vegf 0.4060960234700475 0.4589458660056902 0.6462730407494215 1.0 1.0 29 Q13464,Q16539,Q9UQB8,P46108,O75116,Q96F07,P31751 7
Respiratory electron transport 0.3263247534763424 0.4577815281066114 0.6471094080244582 1.0 1.0 54 Q9Y6M9,Q8N8Q8,Q9UDW1,O14949,O43676,P22695,P03886 7
Resolution of sister chromatid cohesion 0.3368790130038401 0.4554372777931993 0.6487946818320607 1.0 1.0 62 Q9BZD4,O75122,Q8WVM7,O14777,Q96EE3,Q9BW27,P30154,Q15691,Q96BD8,Q8N3U4,Q7Z5K2,Q13509,Q13885,P30153,Q8NI77,Q6IPU0,P57740,Q16537,O00139,Q29RF7,P04350,Q8NFH4,P06493 23
Rho gtpases activate ktn1 0.4401550048135126 0.4553936126503626 0.6488260896603517 1.0 1.0 7 Q9NSK0 1
Ldl clearance 0.4426498356631008 0.4550737419309709 0.6490561879826358 1.0 1.0 13 O15118 1
Dna replication 0.3707306197190573 0.4447142217796738 0.6565262903410658 1.0 1.0 89 P28072,Q9UL46,O00231,P60900,P49721,P28074,P49005,Q9BRT9,P49720,P61289,P40937,Q99436,Q16763,P20618,Q14566,Q9Y619,Q9UJX4,P28070,P15927 19
Glycogen metabolism 0.4404303809591375 0.4446203148124962 0.6565941640487629 1.0 1.0 11 Q93100 1
Mitotic spindle checkpoint 0.3276053032445192 0.4439760018819582 0.6570599344128716 1.0 1.0 56 Q9BZD4,Q9UJX3,O75122,O14777,Q96EE3,Q9BW27,P30154,Q15691,Q96BD8,P30153,Q8NI77,Q6IPU0,Q16763,P57740,Q16537,O00139,Q9UJX4,Q8NFH4,Q9Y266 19
Apoptosis 0.3700104943894712 0.4380265012463348 0.6613670726291716 1.0 1.0 89 P02545,P28072,Q9UL46,Q04917,O00231,Q9P289,P60900,P49721,Q13464,P31946,P27348,P28074,Q9UKG1,Q9UDY2,P49720,P61289,P08670,Q9Y3B8,Q99436,P20618,P25787,P28070,Q13813,P31751 24
Signaling by moderate kinase activity braf mutants 0.4377276427509244 0.4327095707180246 0.665225775942379 1.0 1.0 11 Q7Z569 1
Diseases associated with glycosaminoglycan metabolism 0.4729543710546273 0.4324013773180058 0.665449717257875 1.0 1.0 4 P06865 1
Interferon alpha beta signaling 0.43590900542006 0.4265470488570727 0.6697092724010909 1.0 1.0 10 P10321,P04439,P42224,P01889 4
Late endosomal microautophagy 0.4356518373648662 0.4254400447760058 0.6705159192590229 1.0 1.0 10 P08670 1
Interleukin 4 and interleukin 13 signaling 0.4334153305872306 0.4129072831073865 0.6796745448390098 1.0 1.0 12 P09601 1
Rho gtpases activate iqgaps 0.4315893835071254 0.4059293457752164 0.6847945151605901 1.0 1.0 11 Q86VI3,Q13509,Q13885 3
Cytosolic sulfonation of small molecules 0.4391805165519684 0.3949299404242852 0.6928945930478878 1.0 1.0 5 Q9NX62,O43252 2
Dna damage recognition in gg ner 0.4254995961231523 0.3933913110741902 0.6940304861916666 1.0 1.0 18 P61201,P54725,P41208 3
Hdr through single strand annealing ssa 0.4271705193392501 0.3910702312092769 0.6957453240019786 1.0 1.0 16 P15927,P38398,Q9UQ84 3
Homologous dna pairing and strand exchange 0.4271705193392501 0.3910702312092769 0.6957453240019786 1.0 1.0 16 P15927,P38398,Q9UQ84 3
Death receptor signalling 0.4230865004213106 0.3886284489640192 0.697551018685133 1.0 1.0 19 Q9NQC3,Q8TCT8,O95429 3
P75 ntr receptor mediated signalling 0.4274680949401681 0.3867805023096849 0.6989187128798555 1.0 1.0 12 Q9NQC3,Q92542 2
Adp signalling through p2y purinoceptor 12 0.4368366498520651 0.3866112528507683 0.6990440259929873 1.0 1.0 5 Q9UBI6,P04899,P63096 3
Gaba receptor activation 0.4368366498520651 0.3866112528507683 0.6990440259929873 1.0 1.0 5 Q9UBI6,P04899,P63096 3
Gaba b receptor activation 0.4368366498520651 0.3866112528507683 0.6990440259929873 1.0 1.0 5 Q9UBI6,P04899,P63096 3
Apoptotic cleavage of cell adhesion proteins 0.4194353190348979 0.3776553203115468 0.7056866630729048 1.0 1.0 6 Q9UDY2 1
Synaptic adhesion like molecules 0.4205763631426861 0.3757750032262649 0.7070841726644677 1.0 1.0 7 Q12959 1
Protein protein interactions at synapses 0.423410657072867 0.3734537624574885 0.7088107522673361 1.0 1.0 16 Q12959,Q14168 2
Diseases of signal transduction by growth factor receptors and second messengers 0.4203020084314451 0.3710030812434169 0.7106352367378821 1.0 1.0 138 P02545,P33176,P28072,P49841,O95684,P12270,Q9UL46,O00231,Q92614,Q6UN15,P60900,P06753,Q92542,P49721,Q7Z569,P30154,P31946,P28074,Q13555,P42224,P49720,P61289,O95429,P30153,Q99436,Q9NRY5,P20618,P25787,P10644,P35579,Q14789,P67936,O43252,Q16537,P28070,P35269,P31751 37
Rhoh gtpase cycle 0.4158510973184202 0.3700084866412884 0.7113761670409366 1.0 1.0 21 O75116,Q9BZH6,P02786,P27105,Q99707,O75323 6
Neurotransmitter receptors and postsynaptic signal transmission 0.3562444995182684 0.3595515563152646 0.7191825163233694 1.0 1.0 36 Q12959,Q14168,P10644,Q13555,P54619 5
Rnd3 gtpase cycle 0.4170974618811429 0.3589943691101319 0.7195993016912923 1.0 1.0 19 O43396,O75976,Q13464,Q03001,Q07065,Q9NYL9 6
Extracellular matrix organization 0.3892042904932821 0.3537124215178944 0.7235544126384779 1.0 1.0 29 P20810,P13674,O75718,O15460,P05067,Q03001,Q32P28,P04632,Q9Y296,Q9Y624,Q92542,P11047 12
Synthesis of dolichyl phosphate 0.6768178993163234 0.3515329254632591 0.7251885756955518 1.0 1.0 2 P53602 1
Hyaluronan metabolism 0.4462640468595938 0.3480849846002994 0.7277763606029095 1.0 1.0 4 P06865 1
Hyaluronan uptake and degradation 0.4462640468595938 0.3480849846002994 0.7277763606029095 1.0 1.0 4 P06865 1
Signaling by erbb4 0.4149017327319049 0.3476404579864317 0.7281102181280605 1.0 1.0 8 Q96J02,P61201,Q92542 3
Organelle biogenesis and maintenance 0.3693739332229411 0.3413411630018554 0.7328467630517199 1.0 1.0 97 O95684,Q15051,Q9H6D7,Q13561,P24539,Q13505,Q10713,P07437,Q15154,Q15691,Q92538,Q13509,O00411,O75964,P54619,O00471,Q13885,P30153,Q9Y496,O75935,Q16539,Q16891,A0AVF1,Q8NCM8,Q9NX63,Q96CS2,O94927,P41208,P04350,Q8WYA0,Q9UPT5,Q96RR1,Q9Y512 33
Hdr through homologous recombination hrr 0.4033558004573715 0.3406493444451943 0.7333675773099539 1.0 1.0 24 P15927,P38398,P49005,Q9UQ84 4
Role of abl in robo slit signaling 0.4233506502915668 0.339983122997552 0.7338692376016125 1.0 1.0 5 O75122,O94813,Q9Y6N7 3
Rhoj gtpase cycle 0.4069455390472299 0.3346349860715485 0.7379004499201236 1.0 1.0 22 Q86VI3,Q01968,Q5T2T1,P42166,P02786,P27105 6
Wnt ligand biogenesis and trafficking 0.4208690291337676 0.3316430596499623 0.7401588010977154 1.0 1.0 5 O75436,Q96QK1 2
Defective intrinsic pathway for apoptosis 0.4136895786700321 0.3286923794081075 0.7423882149331384 1.0 1.0 16 P02545,P05067 2
Pyruvate metabolism 0.4120607248753877 0.3243204022071048 0.7456954750248339 1.0 1.0 17 P21796,Q9P0J1 2
Collagen formation 0.41257923464065 0.321654612773416 0.7477143656269511 1.0 1.0 13 P13674,O75718,O15460,Q03001,Q32P28 5
Wax and plasmalogen biosynthesis 0.4359478496595927 0.3176865332713576 0.7507227273295236 1.0 1.0 4 O00116 1
Rhog gtpase cycle 0.3591238375767343 0.3037609190012209 0.7613100427700235 1.0 1.0 34 P50402,O95202,O15173,Q5T2T1,P42166,P02786,O15498,Q86XL3 8
Enos activation 0.4877214796394243 0.2997869073229076 0.7643397027176624 1.0 1.0 3 P07900,O75608 2
S phase 0.364370393233894 0.2853510822296813 0.7753751808768699 1.0 1.0 98 P28072,P49841,Q9UL46,O00231,P60900,P49721,P28074,Q7Z5K2,P49005,Q8N3U4,Q9BRT9,P49720,P61289,P40937,Q99436,Q16763,P20618,Q14566,Q9Y619,Q9UJX4,P28070,P15927 22
Clathrin mediated endocytosis 0.3073609244258529 0.278175120090295 0.7808779326980895 1.0 1.0 54 O43493,Q7L5N1,P01130,Q01968,P11717,Q9BT78,P02786,P20645,P50570,Q9UBC2,P61201,Q9UNF0,Q14108,Q9Y5X1 14
Nuclear envelope ne reassembly 0.2991574258617042 0.2770993196233552 0.7817038442384598 1.0 1.0 48 P50402,P30153,P02545,Q96EE3,Q9BTX1,Q8N1F7,Q9BW27,Q8WUX9,P04350,P42166,P57740,Q13509,Q8NFH5,P06493,Q86XL3,Q13885 16
Diseases of immune system 0.6435674331882999 0.2768595340356911 0.7818879655759223 1.0 1.0 2 O14920 1
Rhoq gtpase cycle 0.3994825402271817 0.2745445742489181 0.78366615371477 1.0 1.0 19 P02786,P27105,Q5T2T1 3
Signaling by hippo 0.3914067491979542 0.2654464890713397 0.7906655270925798 1.0 1.0 7 Q9UDY2,P31946 2
Adrenaline noradrenaline inhibits insulin secretion 0.414935896421034 0.2599842058887907 0.7948759566735424 1.0 1.0 4 P04899,P63096 2
Trafficking of ampa receptors 0.3958704270231692 0.2588741210273368 0.7957323661286515 1.0 1.0 11 Q12959 1
Post chaperonin tubulin folding pathway 0.3932455459104769 0.253435630875003 0.7999315967050782 1.0 1.0 10 Q99426,Q13509,Q13885 3
Regulation of tnfr1 signaling 0.39462029601915 0.2484691185809174 0.8037714608198776 1.0 1.0 5 Q8TCT8 1
Regulation of commissural axon pathfinding by slit and robo 0.4619009840126545 0.2417963543079492 0.8089379639481342 1.0 1.0 3 Q9Y6N7 1
Synthesis of pips at the golgi membrane 0.3865135221507968 0.2408176450350058 0.8096964532625197 1.0 1.0 8 Q10713,Q01968 2
Rho gtpases activate nadph oxidases 0.3820565178162665 0.2406695749361881 0.8098112216075735 1.0 1.0 6 Q13526,Q16539,P05771 3
Mrna decay by 3 to 5 exoribonuclease 0.3921168584075528 0.2341095663135185 0.8148999194367654 1.0 1.0 15 Q96C86,Q969T7 2
Transmission across chemical synapses 0.2961899943314668 0.2339613198471172 0.8150150076095408 1.0 1.0 43 P21964,Q13131,P05771,P52292,P63096,P04350,Q12959,Q14168,Q13885,P04899,P07196,Q13509,P10644,Q13555,P54619 15
Ptk6 regulates cell cycle 0.6202610316967161 0.2311944994637433 0.817163703055062 1.0 1.0 2 P24941 1
Cargo concentration in the er 0.3899840242990379 0.2266911025290316 0.8206639461785663 1.0 1.0 14 Q96PC5 1
Apc c cdc20 mediated degradation of cyclin b 0.3878859153611929 0.224185822819836 0.8226127144894444 1.0 1.0 12 Q9UJX4,P14635,P06493,Q16763,Q96DE5,Q9UJX3,Q9UJX5 7
Mtor signalling 0.3857326051507095 0.2097931424729399 0.8338291254801911 1.0 1.0 14 Q13131,Q15382,P31946,P31751,P54619 5
Transcriptional regulation by runx1 0.3214706530245103 0.2038101659401538 0.8385018483137046 1.0 1.0 71 P49720,P61289,P28072,P49721,Q9UL46,Q99436,P28070,O00231,P28074,Q8TAQ2,Q9HCL2,P20618,Q96J02,P60900 14
Synthesis of substrates in n glycan biosythesis 0.3831164751065841 0.1995464377850032 0.8418353215799506 1.0 1.0 14 P16278,P10619 2
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.310196583023819 0.1956437308415993 0.8448890293947064 1.0 1.0 63 Q9Y6M9,Q8N8Q8,Q9UDW1,O14949,O43676,P24539,P22695,P03886 8
Antigen presentation folding assembly and peptide loading of class i mhc 0.3824403922807774 0.1938860965991962 0.8462650704311816 1.0 1.0 17 P10321,Q6P179,Q03519,Q9NZ08 4
G1 s specific transcription 0.3764592571234292 0.1866041126718242 0.8519710419453195 1.0 1.0 11 P31350 1
Ca2 pathway 0.372317262830478 0.1857996206054791 0.8526019020656013 1.0 1.0 5 P35222,Q9UBI6,Q9HCE1,Q08209 4
Interleukin 12 signaling 0.3665190584359182 0.1855501387131756 0.8527975579454312 1.0 1.0 27 Q13126,P14174 2
Transcriptional regulation by e2f6 0.3682317175743814 0.1784147693550227 0.8583972511206628 1.0 1.0 8 P31350 1
Glycerophospholipid biosynthesis 0.34445703448411 0.1773799157970384 0.8592099820363241 1.0 1.0 33 Q8N2A8,Q8IV08,P35790,Q9HCL2 4
Activation of rac1 0.3689986571781319 0.1771578659206953 0.8593843902383584 1.0 1.0 5 Q9Y6N7 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3690847008425389 0.1740313170509377 0.8618408503166914 1.0 1.0 25 Q13126,P14174 2
Pten regulation 0.3097046080688285 0.1681805142551863 0.8664412699661259 1.0 1.0 65 P28072,P49721,O00231,P28074,P20618,P60900 6
Cohesin loading onto chromatin 0.3685507727979085 0.1651684922028515 0.8688113642017776 1.0 1.0 10 Q9Y6X3,Q8N3U4,Q7Z5K2 3
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3662774421749618 0.1575683194112659 0.874796969111252 1.0 1.0 10 Q9UJX3,Q16763,Q9UJX4,Q96DE5 4
Synthesis of pips at the late endosome membrane 0.4143612060926372 0.1565435412087069 0.875604601348078 1.0 1.0 3 O00443,Q99570 2
Anti inflammatory response favouring leishmania parasite infection 0.3696993723315936 0.145829825864985 0.8840557299589551 1.0 1.0 15 P10644,P35579,Q16539,P63096 4
Traf6 mediated induction of tak1 complex within tlr4 complex 0.5646364201367428 0.1454738181330755 0.8843367859385192 1.0 1.0 2 Q15750 1
Phospholipid metabolism 0.2923708457586682 0.14238847573497 0.8867731646704562 1.0 1.0 54 P35790,Q10713,Q8N2A8,Q8IV08,Q9HCL2 5
Synthesis of pips at the early endosome membrane 0.3545878693623543 0.1417870716110065 0.8872481962536121 1.0 1.0 5 O00443,Q99570,Q96PE3,Q13614 4
Signaling by wnt 0.3325732239371943 0.1357409660860543 0.8920260611722015 1.0 1.0 86 P49720,P61289,Q16537,P30153,P49721,P28072,P49841,P30154,Q96QK1,Q9UL46,P28070,Q99436,O00231,P28074,P20618,P25787,P60900,P31751 18
Meiotic synapsis 0.3667901230642693 0.1326011240123822 0.894508843438615 1.0 1.0 16 P02545,Q8WXH0,P38398,Q8N3U4,Q8WVM7,Q9UH99 6
Pi5p regulates tp53 acetylation 0.3966483175835085 0.132072203840367 0.8949271814127984 1.0 1.0 3 Q13526 1
Fatty acyl coa biosynthesis 0.3648802593791195 0.1280726095446987 0.8980915119307338 1.0 1.0 15 P50897,P33121 2
Plasma lipoprotein remodeling 0.5478558110627851 0.1259649290977039 0.8997596859222274 1.0 1.0 2 P07237 1
Prolactin receptor signaling 0.3894933167547486 0.1232849587700817 0.90188145112935 1.0 1.0 3 P63208,Q13616 2
Regulation of beta cell development 0.3420398009950181 0.1095123927349615 0.912796092906893 1.0 1.0 4 Q13573,Q06330,P31751 3
Sensory processing of sound 0.3597531230301991 0.1066220293664588 0.9150888412998736 1.0 1.0 16 Q13813,P35579,Q00013,Q6IBS0 4
Copi independent golgi to er retrograde traffic 0.3531550451839838 0.1058714086086819 0.915684379171264 1.0 1.0 26 O75935,Q8TD16,Q13509,Q13561,Q10472,Q13885 6
G beta gamma signalling through pi3kgamma 0.3720857942182259 0.1044482099818996 0.9168136658364424 1.0 1.0 3 Q9UBI6,P31751 2
G protein activation 0.3720857942182237 0.1044482099818976 0.916813665836444 1.0 1.0 3 Q9UBI6,P50148 2
Activation of nima kinases nek9 nek6 nek7 0.3373756218905421 0.1026537981446905 0.9182377435852233 1.0 1.0 4 P06493,P53350,P14635 3
Phosphorylation of emi1 0.3702207025178813 0.1026370935436539 0.9182510018988104 1.0 1.0 3 P06493,P14635 2
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5201988812927387 0.0997813265859214 0.9205179332802904 1.0 1.0 2 Q15750 1
Regulation of innate immune responses to cytosolic dna 0.3646254274168541 0.0974359135871408 0.922380225482332 1.0 1.0 3 Q9UJV9,P19474 2
Rho gtpases activate wasps and waves 0.3554307635939246 0.0911795161996259 0.9273499508502998 1.0 1.0 16 Q9NZQ3,Q9UQB8 2
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.356336057365591 0.0902631769509113 0.9280780812016796 1.0 1.0 18 P16278,P10619 2
Rho gtpases activate pkns 0.3547387298806578 0.0860805068753232 0.9314024193590966 1.0 1.0 17 Q9Y3B8,P31946,Q04917,P27348,Q7Z406,P35579,Q16513,P35580 8
Synthesis of ip2 ip and ins in the cytosol 0.3500155424308395 0.0854364162909936 0.9319144429748224 1.0 1.0 3 Q96PE3,Q01968 2
Cytosolic iron sulfur cluster assembly 0.3295616992662757 0.0853591088392508 0.931975900888458 1.0 1.0 6 Q9Y5Y2 1
Signaling by interleukins 0.3494720924631829 0.0846228115157651 0.93256126314794 1.0 1.0 105 Q13126,P28072,Q9UL46,P14174,O00231,P60900,P49721,P28074,O14979,P42224,P49720,P61289,P08670,P30153,Q99436,P09601,P05067,Q16539,P46108,O14920,P20618,P28070 22
Non integrin membrane ecm interactions 0.3289801162084548 0.0839232583510431 0.933117447301032 1.0 1.0 6 P11047 1
Vxpx cargo targeting to cilium 0.3372781065088784 0.0775575091779665 0.9381800432857068 1.0 1.0 9 O00471,Q96KP1,P61006,P18085,Q8TAG9,O60645,Q92538,Q9UPT5 8
Processing of smdt1 0.3416066874589325 0.0738246534537753 0.9411499099291918 1.0 1.0 11 Q10713 1
Ngf stimulated transcription 0.3298103823438022 0.0723135377539975 0.9423523913331222 1.0 1.0 3 Q00535,P50570 2
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.331361206066872 0.070779496435613 0.943573250364924 1.0 1.0 8 Q16763 1
Inactivation of cdc42 and rac1 0.3115546356712323 0.070512378697341 0.9437858482990478 1.0 1.0 4 Q9Y6N7 1
Regulation of tp53 activity through association with co factors 0.3263910475598475 0.0704562400974352 0.9438305292947696 1.0 1.0 3 Q13625,P31751 2
Clec7a dectin 1 induces nfat activation 0.4695463020509747 0.068518810905633 0.9453726463275716 1.0 1.0 2 Q08209 1
Degradation of the extracellular matrix 0.3338311801439771 0.068326811941517 0.9455254811554724 1.0 1.0 9 P04632,P11047 2
P130cas linkage to mapk signaling for integrins 0.3086219574408236 0.0674622325579346 0.9462137275532974 1.0 1.0 4 P46108 1
Robo receptors bind akap5 0.467060285891875 0.0674523858811644 0.946221566209505 1.0 1.0 2 P13861 1
Vegfr2 mediated cell proliferation 0.3081467661691464 0.0669790474903151 0.9465983834167856 1.0 1.0 4 P05771,O43865,P19174 3
Maturation of sars cov 2 nucleoprotein 0.3157076205287637 0.064504437670399 0.9485685737225982 1.0 1.0 5 P49841,Q99873,P48729,P78362 4
Zbp1 dai mediated induction of type i ifns 0.302549751243773 0.0615158553983454 0.9509483875381172 1.0 1.0 4 O14920,Q13546,Q9NZI8 3
Rip mediated nfkb activation via zbp1 0.302549751243773 0.0615158553983454 0.9509483875381172 1.0 1.0 4 O14920,Q13546,Q9NZI8 3
Regulation of ifna signaling 0.2931302455704111 0.0570175317846418 0.9545312295150696 1.0 1.0 3 Q06124,P42224 2
Regulation of ifng signaling 0.2931302455704111 0.0570175317846418 0.9545312295150696 1.0 1.0 3 Q06124,P42224 2
Rhov gtpase cycle 0.3434143181572099 0.0548378011378432 0.95626768474437 1.0 1.0 15 P06753,P67936,Q13813,Q03001 4
Adp signalling through p2y purinoceptor 1 0.3082426127527178 0.0527258133581643 0.9579503715421824 1.0 1.0 5 Q9UBI6,Q16539,P50148,P63218 4
Nuclear receptor transcription pathway 0.4114356743318942 0.0518804420055564 0.9586239583043944 1.0 1.0 2 Q9UHY1 1
Syndecan interactions 0.2913233721036819 0.0517820457536759 0.9587023617692308 1.0 1.0 4 Q9Y296 1
Interleukin 6 signaling 0.2704382965495842 0.0517088511107556 0.95876068451021 1.0 1.0 3 Q06124,P42224 2
Interleukin 20 family signaling 0.2704382965495842 0.0517088511107556 0.95876068451021 1.0 1.0 3 Q06124,P42224 2
Interleukin 6 family signaling 0.2704382965495842 0.0517088511107556 0.95876068451021 1.0 1.0 3 Q06124,P42224 2
Interleukin receptor shc signaling 0.2604911408144286 0.0501073426665559 0.9600368484885476 1.0 1.0 3 O00459,O15357 2
G protein beta gamma signalling 0.3063763608087049 0.0499324572976154 0.960176212371513 1.0 1.0 5 Q9UBI6,Q16512,P31751,P63218 4
Rho gtpases activate formins 0.2893574185244946 0.0490890880194472 0.9608482994236244 1.0 1.0 60 P30153,Q16537,Q96EE3,O00139,Q8NI77,Q6IPU0,P30154,Q9BZD4,P04350,Q15691,Q96BD8,O75122,Q9NSV4,P57740,Q13509,O14777,Q13885 17
Mapk3 erk1 activation 0.3893722809198384 0.048933778139516 0.9609720700335652 1.0 1.0 2 P06493 1
Dissolution of fibrin clot 0.3778744561839743 0.0478671127204695 0.9618221495798542 1.0 1.0 2 P07355 1
Prostacyclin signalling through prostacyclin receptor 0.3719701678061062 0.0474190925184878 0.9621792125065514 1.0 1.0 2 Q9UBI6 1
Inwardly rectifying k channels 0.3719701678061062 0.0474190925184878 0.9621792125065514 1.0 1.0 2 Q9UBI6 1
Potassium channels 0.3719701678061062 0.0474190925184878 0.9621792125065514 1.0 1.0 2 Q9UBI6 1
Glucagon type ligand receptors 0.3719701678061062 0.0474190925184878 0.9621792125065514 1.0 1.0 2 Q9UBI6 1
Presynaptic function of kainate receptors 0.3719701678061062 0.0474190925184878 0.9621792125065514 1.0 1.0 2 Q9UBI6 1
Intracellular signaling by second messengers 0.3201946581866738 0.0425978305011968 0.9660221249313908 1.0 1.0 85 Q16537,P28072,P49721,O00231,P28074,P20618,P10644,P60900,Q13555 9
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3322276373287789 0.0401405391673138 0.9679810822492034 1.0 1.0 12 Q16763 1
Apc cdc20 mediated degradation of nek2a 0.3322276373287789 0.0401405391673138 0.9679810822492034 1.0 1.0 12 Q16763 1
Synthesis of ip3 and ip4 in the cytosol 0.2736318407960121 0.039502443920314 0.9684898050726244 1.0 1.0 4 O15357,Q01968,P19174 3
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.2714552238805897 0.038229094055442 0.9695050241435696 1.0 1.0 4 P46108,Q96JJ3,P63000 3
Programmed cell death 0.3389391837388705 0.0373852280832242 0.9701778507194588 1.0 1.0 101 P02545,P28072,Q9UL46,Q04917,O00231,Q9P289,P60900,P49721,Q13464,P31946,P27348,Q15149,P28074,Q9UKG1,Q9UDY2,P49720,P61289,P08670,Q9Y3B8,Q99436,P20618,P25787,P28070,Q13813,P31751 25
Estrogen dependent nuclear events downstream of esr membrane signaling 0.269001005199376 0.0368515045363566 0.9706034072310328 1.0 1.0 4 P31751 1
Metabolism of fat soluble vitamins 0.2946860077500379 0.0337853178895904 0.973048343889261 1.0 1.0 5 Q07954,P01130 2
Constitutive signaling by overexpressed erbb2 0.2605721393034773 0.0325689803807339 0.9740183067712802 1.0 1.0 4 P07900,Q16543,Q96RT1 3
Vegfr2 mediated vascular permeability 0.3230529595015601 0.0322782775706542 0.9742501321643188 1.0 1.0 10 Q16512,Q13177,O60716,P35221,P35222,P14923,P42345,P07900,P31751 9
Unwinding of dna 0.319275261373163 0.0320735747448972 0.9744133768635624 1.0 1.0 9 Q14566,Q9BRT9 2
Phosphorylation of the apc c 0.3318448931734443 0.0320562975237436 0.9744271550066844 1.0 1.0 13 Q9UJX4,P14635,P06493,Q16763,Q96DE5,Q9UJX3,Q9UJX5 7
Rhobtb1 gtpase cycle 0.3399626264127515 0.0283139836806106 0.9774117277073832 1.0 1.0 20 P08670,P61201,Q5VTR2,O75116 4
G alpha s signalling events 0.3084344849050728 0.0273632469648657 0.978170011938 1.0 1.0 7 Q9UBI6,P63218,P63096,P08754,P04899,Q9Y3E5 6
Copii mediated vesicle transport 0.330172123411789 0.0260296803800002 0.9792336649471624 1.0 1.0 29 P53634,Q9Y6Y8,Q08379,Q99747,Q9Y296,O00743,O15498 7
Muscle contraction 0.335587247450186 0.0251797617665809 0.9799115796089088 1.0 1.0 26 Q13555,P67936 2
Methylation 0.300765419736467 0.0223580496800441 0.9821623434847242 1.0 1.0 6 P21964 1
Translation of replicase and assembly of the replication transcription complex 0.2836702954898802 0.0206382646695345 0.9835342161671315 1.0 1.0 5 Q9Y3E7,Q9UQN3,Q99570,Q8WUX9 4
Reduction of cytosolic ca levels 0.2217039800994958 0.0202076630504939 0.9838777149044732 1.0 1.0 4 P23634,P20020,P16615 3
Platelet calcium homeostasis 0.2217039800994958 0.0202076630504939 0.9838777149044732 1.0 1.0 4 P23634,P20020,P16615 3
Rna polymerase iii transcription initiation from type 3 promoter 0.2980709396390769 0.0173145880886824 0.98618564773636 1.0 1.0 6 O14802,O15160,P62875,P19388,Q9BUI4 5
Rna polymerase iii chain elongation 0.2980709396390769 0.0173145880886824 0.98618564773636 1.0 1.0 6 O14802,O15160,P62875,P19388,Q9BUI4 5
Downregulation of erbb2 signaling 0.2977483769211699 0.0167205744183546 0.9866595334426926 1.0 1.0 6 P31751 1
Activation of atr in response to replication stress 0.3366523913697249 0.0166267670390183 0.9867343704988304 1.0 1.0 20 P15927,P40937,Q9Y619 3
Met activates rap1 and rac1 0.2786880637308974 0.0153235905918061 0.9877740221211992 1.0 1.0 5 Q96N67 1
Foxo mediated transcription 0.3153959541002017 0.0141511416095994 0.9887093994260664 1.0 1.0 10 P31946,P27348,Q9Y3B8 3
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.332837484061585 0.0126805252168666 0.9898826758443872 1.0 1.0 17 Q13509,Q99471,Q9UHV9,Q13885 4
Interleukin 12 family signaling 0.3247081383398236 0.0110267111139092 0.9912021357324514 1.0 1.0 30 Q13126,P14174 2
Fcgamma receptor fcgr dependent phagocytosis 0.3241789552583932 0.0084446997551156 0.9932621845271268 1.0 1.0 30 Q9UQB8 1
Signal amplification 0.3086265960759912 0.008392835223927 0.993303564969352 1.0 1.0 9 Q9UBI6,P50148,P63218,P63096,Q16539,Q14344,P08754,P04899 8
G alpha 12 13 signalling events 0.2977560322824003 0.006463375409156 0.9948430084561306 1.0 1.0 7 Q13464,O75116 2
Synthesis of pa 0.3189078576278328 0.0056648811781464 0.9954801029437652 1.0 1.0 12 Q8N2A8,Q8NAN2,Q9HCL2 3
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