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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Proteasome degradation 0.5668233717207858 2.355586495695548 0.0184934910290293 0.9999858053710992 1.0 40 P49720,P61289,P04439,P28072,P49721,Q9UL46,Q99436,P10321,P28070,O00231,P28074,P20618,P60900 13
Degradation pathway of sphingolipids including diseases 0.8522867546733343 2.31423253187617 0.0206549703847376 0.999996201932576 1.0 6 P06280,P17900,P16278 3
Glycosaminoglycan degradation 0.7913180972899183 2.051300207835504 0.04023772026122 0.9999999999784286 1.0 6 P06865,P16278,P54802 3
Oxidation by cytochrome p450 0.7813222948245666 2.0074481308474743 0.0447019683099665 0.9999999999986724 1.0 6 O43169,Q6UW02 2
Acquired partial lipodystrophy barraquersimons syndrome 0.8072228682201529 1.9590227985255873 0.0501101168829483 0.9999999999999556 1.0 5 O60725 1
Disruption of postsynaptic signaling by cnv 0.7623465775833214 1.9481242786900412 0.051400094395082 0.9999999999999802 1.0 8 Q12959,Q14168 2
Vitamin a and carotenoid metabolism 0.7896793283975658 1.8846418658198776 0.0594782059602445 1.0 1.0 5 Q8WTV0 1
Familial partial lipodystrophy fpld 0.7471794279086075 1.87923309924496 0.0602126719991 1.0 1.0 8 O75844,O60725 2
Striated muscle contraction pathway 0.8156094527363155 1.7969899492436108 0.0723372153780055 1.0 1.0 4 P08670,P06753,P67936 3
Copper homeostasis 0.72547997235027 1.7685274764925216 0.0769727629377157 1.0 1.0 7 P35670,P05067,Q04656 3
Genes related to primary cilium development based on crispr 0.7018135654392007 1.7664984021750518 0.0773122694005583 1.0 1.0 14 O95684,Q8NCM8,Q9Y496,Q10713 4
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7618331888472349 1.7655336953495464 0.0774741123852114 1.0 1.0 5 P07099 1
Metabolism of spingolipids in er and golgi apparatus 0.7614957424843861 1.764082766413415 0.0777180454987418 1.0 1.0 5 Q16739,O95470,Q10472 3
Sphingolipid metabolism overview 0.7162243987518009 1.737172547775516 0.082356718968191 1.0 1.0 8 Q16739,O15269,Q06136,Q96G23,O95470 5
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6840860235639403 1.6994820832105026 0.0892283876045179 1.0 1.0 15 P02545,P49841,O75844,P42166,P55209,O60725 6
Fatty acid transporters 0.7451199687754304 1.6934653628368208 0.0903669224995908 1.0 1.0 5 Q6P1M0,P33121 2
Ferroptosis 0.6509240592130169 1.6908435452425836 0.0908666879690913 1.0 1.0 21 P33121,P09601,Q15043,P02786,P45880,P08195 6
Progeriaassociated lipodystrophy 0.6938306197713769 1.6575516441034492 0.0974079967666938 1.0 1.0 10 O75844,O60725 2
Ketogenesis and ketolysis 0.7313329210580756 1.6337123844371912 0.1023192567126387 1.0 1.0 5 P23786,O43772 2
Sphingolipid pathway 0.6817408931714847 1.629497256385969 0.1032077952167183 1.0 1.0 12 Q16739,O15269,Q06136,P04062,Q9Y5P4,Q96G23,O95470 7
Sphingolipid metabolism integrated pathway 0.688419076406056 1.6190681874439008 0.1054325926922503 1.0 1.0 9 Q16739,O15269,Q06136,Q96G23,O95470 5
Metapathway biotransformation phase i and ii 0.611051746923039 1.4673880218014883 0.1422705310695478 1.0 1.0 21 Q16850,P34913,P07099,Q7LGA3,Q6UW02 5
Vitamin d metabolism 0.8259986103589564 1.4664862217956127 0.1425158720989059 1.0 1.0 3 P04062 1
3q29 copy number variation syndrome 0.6452689787946653 1.4496971370689853 0.1471429944654061 1.0 1.0 12 O95684,Q12959,P02786 3
Mitochondrial complex iii assembly 0.6504980143585842 1.4494624201668846 0.1472084877753148 1.0 1.0 10 Q9BRT2,P08574,Q9UDW1,O14949,P22695 5
Cannabinoid receptor signaling 0.6795075871204854 1.4070532609178457 0.1594115960486957 1.0 1.0 5 P10644 1
Sphingolipid metabolism in senescence 0.6318558766518196 1.3975388590972524 0.162251589664959 1.0 1.0 13 Q16739,P16278,P04062 3
Familial hyperlipidemia type 3 0.7998134908299367 1.3663849331499196 0.1718181753338965 1.0 1.0 3 Q8WTV0,P01130 2
Nephrotic syndrome 0.6222344809149898 1.3646336234324936 0.172368231371867 1.0 1.0 14 P02545,O75844,Q14108 3
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.7952378756183405 1.3488888081085182 0.1773726835852596 1.0 1.0 3 P09601 1
Regulation of wnt bcatenin signaling by small molecule compounds 0.7020832468279714 1.329855020254146 0.1835660437501949 1.0 1.0 4 P49841 1
Signal transduction through il1r 0.7007390121137703 1.3242756533860351 0.1854115132857101 1.0 1.0 4 Q16539 1
Alzheimers disease and mirna effects 0.4518864719251297 1.2787921733044425 0.2009702507798614 1.0 1.0 84 P33176,P28072,P49841,O95197,P21796,P60900,Q92542,P49721,P28074,Q13509,P45880,P49720,Q9NQC3,Q99436,P05067,O14920,P20618,P25787,P28070,Q9NSK0,Q96IX5,P31751 22
Mirnas involvement in the immune response in sepsis 0.7731397286415822 1.2644408428325968 0.2060718411283115 1.0 1.0 3 Q16539 1
Vitamin d in inflammatory diseases 0.6828358208955181 1.2499623294632982 0.2113133086358514 1.0 1.0 4 O14920,Q16539,O60244 3
Cellular proteostasis 0.6779974679093 1.229885697721786 0.2187399107300165 1.0 1.0 4 Q99471 1
Il10 antiinflammatory signaling pathway 0.6744024889558518 1.214972820433201 0.2243764578681433 1.0 1.0 4 P09601 1
Alzheimers disease 0.4430472523859505 1.2075268796452765 0.2272292997530689 1.0 1.0 83 P33176,P28072,P49841,O95197,P21796,P60900,Q92542,P49721,P28074,Q13509,P45880,P49720,Q9NQC3,Q99436,P05067,O14920,P20618,P25787,P28070,Q9NSK0,P31751 21
Intracellular trafficking proteins involved in cmt neuropathy 0.591198561048724 1.153496560159677 0.2487066286451682 1.0 1.0 9 Q8TB36,Q9NR77,P07196,Q6UWE0,O95140 5
Adipogenesis 0.5781467338442646 1.1252377060941186 0.2604883190019684 1.0 1.0 13 P02545,P14174,O75844 3
Neuroinflammation 0.7247801383153318 1.080615228739854 0.2798683055295714 1.0 1.0 3 Q16539 1
Airway smooth muscle cell contraction 0.5989795155246107 1.0519940294689132 0.2928022889121306 1.0 1.0 5 O75116 1
Influence of laminopathies on wnt signaling 0.5646425417239223 1.0379148226968502 0.2993097120221462 1.0 1.0 11 O75844,O60725 2
Kennedy pathway from sphingolipids 0.5950367655557264 1.0346723025236015 0.3008219752641796 1.0 1.0 5 P35790 1
1q211 copy number variation syndrome 0.5622065422688082 1.0258609133361378 0.3049571488819969 1.0 1.0 11 Q13131,Q16625,Q9Y624,Q9UDY2,P54619 5
Pkcgamma calcium signaling pathway in ataxia 0.7074213326161348 1.015281633403158 0.3099715968742169 1.0 1.0 3 Q15118 1
Inclusion body myositis 0.8719701678060764 0.9532201017471416 0.3404785634996732 1.0 1.0 2 P05067 1
Familial hyperlipidemia type 5 0.6736089524401441 0.8897024140438193 0.3736256974428462 1.0 1.0 3 Q07954,P01130 2
Familial hyperlipidemia type 1 0.6736089524401441 0.8897024140438193 0.3736256974428462 1.0 1.0 3 Q07954,P01130 2
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.5225731685398396 0.8434551224515461 0.3989739544942263 1.0 1.0 13 P56537,O75822,P55010,O00303 4
Immune response to tuberculosis 0.6601455534669298 0.8405184257804517 0.4006177748980866 1.0 1.0 3 P42224 1
Melatonin metabolism and effects 0.838719701678041 0.8373470535978992 0.4023975176131515 1.0 1.0 2 P42892 1
Nongenomic actions of 125 dihydroxyvitamin d3 0.5251384107880218 0.8333884896298399 0.4046256642120107 1.0 1.0 7 O14920,Q13555,Q16539,P42224 4
Purinergic signaling 0.6580665216039665 0.832973627392055 0.4048596030757165 1.0 1.0 3 P04899,P63096 2
Nonalcoholic fatty liver disease 0.3561705813406705 0.7774989314295249 0.4368644646526953 1.0 1.0 52 P51970,O95168,O14548,Q13131,P14406,P49841,Q9Y6M9,P08574,O14949,Q9UDW1,O96000,O14920,O43676,Q96J02,P22695,P54619 16
Interactions between loxl4 and oxidative stress pathway 0.6406589990674494 0.7703963782685737 0.4410648011386702 1.0 1.0 3 Q8TAG9,Q16543 2
Cardiac progenitor differentiation 0.8178993163455581 0.7666819052177395 0.4432706646123563 1.0 1.0 2 P49841 1
Monoamine transport 0.8178993163455355 0.7666819052176641 0.4432706646124011 1.0 1.0 2 O15127 1
Myometrial relaxation and contraction pathways 0.4890140309350812 0.7517704781504172 0.4521890984666394 1.0 1.0 20 Q9Y3B8,P31946,Q04917,P10644,Q13555 5
Triacylglyceride synthesis 0.5288419643727335 0.7485126224017158 0.4541510144031659 1.0 1.0 5 O00116,Q9HCL2 2
Electron transport chain oxphos system in mitochondria 0.3461105265859187 0.6780146513080985 0.4977624036550474 1.0 1.0 52 P14406,Q9Y6M9,O14949,Q9UDW1,O43676,P24539,P22695,P03886 8
Familial hyperlipidemia type 4 0.5406634699087924 0.6750369614385597 0.4996522823642331 1.0 1.0 4 P01130 1
Camkk2 pathway 0.4885050754976199 0.6636229989349136 0.5069316334871186 1.0 1.0 9 P09601,O76024 2
Oxidative stress response 0.4870973918452448 0.662123636759641 0.5078919886306816 1.0 1.0 6 P09601,Q16539 2
Wnt signaling pathway and pluripotency 0.4805032275885095 0.6466250709252412 0.517874627986467 1.0 1.0 15 P30153,Q16537,P49841,P30154,P01130 5
Calcium regulation in cardiac cells 0.4506446348678068 0.6314051933006258 0.5277756212244376 1.0 1.0 25 P23634,P05771,Q9Y3B8,P63096,P31946,Q04917,P27348,P10644,Q13555 9
Nucleotidebinding oligomerization domain nod pathway 0.4769532742833596 0.6140559977646599 0.53917832397428 1.0 1.0 7 O14920,Q9Y2Z0,Q7L5N1 3
Hostpathogen interaction of human coronaviruses apoptosis 0.7681789931634597 0.6057450803366538 0.5446840437408544 1.0 1.0 2 Q16539 1
Spinal cord injury 0.4690677684978048 0.6052226147444791 0.5450310915068739 1.0 1.0 17 P08670,Q9NQC3,P14174 3
T cell receptor and costimulatory signaling 0.4941249902652083 0.6048907790644356 0.5452515703515954 1.0 1.0 5 P49841 1
Mitochondrial complex iv assembly 0.46645260338403 0.5625477407147779 0.5737428861885929 1.0 1.0 11 Q9Y2R0,Q8N8Q8 2
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4633301347048312 0.55574872182879 0.5783826444751656 1.0 1.0 14 P05067 1
Primary focal segmental glomerulosclerosis fsgs 0.4535458384270883 0.5450713254072826 0.5857044632395052 1.0 1.0 19 P08670,P27348,O43707,Q14108,P11047 5
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.4579001809160168 0.5350119393514229 0.5926416013463476 1.0 1.0 6 P49841,Q15118,Q15382 3
Translation factors 0.3789359688851352 0.530593384786653 0.5957005807970956 1.0 1.0 36 O75153,Q15056,P55010,O00303,O15372,O75822,P56537 7
Type i collagen synthesis in the context of osteogenesis imperfecta 0.4510940240586765 0.4926464857375008 0.6222623959597278 1.0 1.0 12 O15460,P13674,Q32P28 3
Serotonin and anxiety 0.5573020070723542 0.4915197174824696 0.62305890985989 1.0 1.0 3 P05771 1
Riboflavin and coq disorders 0.4473195030226342 0.4904016373384108 0.6238497182894638 1.0 1.0 6 Q8NFF5,Q86YH6,O75208,Q16134 4
Initiation of transcription and translation elongation at the hiv1 ltr 0.4498178445360155 0.4892499513339333 0.6246647493222026 1.0 1.0 9 Q8IXH7 1
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.4833832223003229 0.4673488262283825 0.6402503287537358 1.0 1.0 4 P61201 1
Hippo signaling regulation pathways 0.4357286974047118 0.437161372864084 0.6619943208256593 1.0 1.0 17 Q13131,P05771,Q13043,P10644,P54619 5
Kisspeptinkisspeptin receptor system in the ovary 0.4743563269209594 0.4370382224747919 0.6620836284457823 1.0 1.0 4 Q15118,P31751 2
Dna mismatch repair 0.4305166941047215 0.4180986214152125 0.6758750128690374 1.0 1.0 18 P15927,P49005,Q9UQ84 3
Hepatitis c and hepatocellular carcinoma 0.4327197278376709 0.4158841013685151 0.6774948138292376 1.0 1.0 9 P38398,P31350 2
Allograft rejection 0.4327180654789591 0.4158771052056398 0.677499933510314 1.0 1.0 9 P08670,P10321,P04439,P08183 4
Omega3 omega6 fatty acid synthesis 0.4285335226226091 0.4135916026433108 0.679173224123758 1.0 1.0 6 P33121 1
Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.4258591859782972 0.3812876638014424 0.7029898063999516 1.0 1.0 11 P49841,Q12959,Q15118 3
Burn wound healing 0.4215757394091667 0.3742684478663117 0.7082046040144543 1.0 1.0 8 P08670 1
Ciliopathies 0.4225953868409783 0.3737395156336978 0.7085981230600167 1.0 1.0 17 Q10713,Q9UBB4,Q01968,Q9ULC3,Q8WYA0,Q15051,Q8NCM8 7
G protein signaling pathways 0.4231532237785601 0.3722535553806091 0.7097040751222097 1.0 1.0 16 P10644 1
Eicosanoid metabolism via lipooxygenases lox 0.4168852631230312 0.3677466145224295 0.7130621790478306 1.0 1.0 6 Q8N8N7 1
Serotonin and anxietyrelated events 0.6824114356743396 0.3651381062499461 0.7150083170849144 1.0 1.0 2 P05771 1
7oxoc and 7betahc pathways 0.4208410420288506 0.3628640940080329 0.7167064100543925 1.0 1.0 10 O15118 1
Resistin as a regulator of inflammation 0.4117519656879213 0.3016835824327268 0.7628932848289918 1.0 1.0 5 O14920,Q16539 2
Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.4279171751408185 0.2949451646102589 0.7680357694089741 1.0 1.0 4 P42224 1
S1p receptor signal transduction 0.3964507931785658 0.2837167711309531 0.7766274411495162 1.0 1.0 7 Q13510,P31751,P63096 3
Supression of hmgb1 mediated inflammation by thbd 0.6435674331882999 0.2768595340356911 0.7818879655759223 1.0 1.0 2 O14920 1
Dna repair pathways full network 0.2998789002310105 0.271198759126968 0.7862381673042751 1.0 1.0 49 P54725,Q9UQ84,P41208,P15927,P38398,P49005 6
Gpr143 in melanocytes and retinal pigment epithelium cells 0.4672054709356644 0.2530602067927969 0.8002216885735205 1.0 1.0 3 P50148,P05771 2
Arrhythmogenic right ventricular cardiomyopathy 0.3934950455075028 0.2458692105124735 0.8057834787646592 1.0 1.0 12 P50402,P02545,O43707 3
Ethanol effects on histone modifications 0.3907595716540458 0.2392608396664943 0.8109033290348293 1.0 1.0 11 O94788,Q99707,P00374 3
15q112 copy number variation syndrome 0.4060945273631796 0.2375028061733517 0.8122667424645558 1.0 1.0 4 Q06787,Q9BSJ2,Q7L576 3
Regulation of apoptosis by parathyroid hormonerelated protein 0.4561235112589552 0.2299204275152645 0.818153602651593 1.0 1.0 3 P49841 1
Prostaglandin and leukotriene metabolism in senescence 0.4516630400994811 0.2210343499758418 0.8250656869585051 1.0 1.0 3 P50148,P63096 2
Tolllike receptor signaling pathway 0.3818402767851578 0.2175375857421056 0.8277894190457804 1.0 1.0 9 O14920,Q16539,P42224 3
Estrogen signaling pathway 0.3924948553659828 0.2051200174459926 0.8374783572771276 1.0 1.0 4 Q16539 1
Serotonin htr1 group and fos pathway 0.3792385094729381 0.2044043452198614 0.8380375348748776 1.0 1.0 5 Q16539,P63096 2
Serine metabolism 0.370820698021968 0.2034105484221952 0.8388141557067017 1.0 1.0 6 P00374 1
Synaptic signaling pathways associated with autism spectrum disorder 0.3830343402173249 0.2021026047518598 0.8398365115873156 1.0 1.0 13 Q13131,P49841,Q05086,P31751,P54619 5
Insulin signaling in adipocytes normal condition 0.3906896734884411 0.2010269011679637 0.840677539331883 1.0 1.0 4 P31751 1
Insulin signaling in adipocytes diabetic condition 0.3906896734884411 0.2010269011679637 0.840677539331883 1.0 1.0 4 P31751 1
Nicotine effect on dopaminergic neurons 0.3905472636815862 0.200706073057182 0.8409284107350083 1.0 1.0 4 P62136,P17612,P63096 3
Eicosanoid metabolism via cyclooxygenases cox 0.3697503410796164 0.1999671707460036 0.8415062564859275 1.0 1.0 6 Q8N8N7 1
Map3k1 role in promoting and blocking gonadal determination 0.3863047873838617 0.1912882753949889 0.8482997463647577 1.0 1.0 4 P49841 1
Extracellular vesiclemediated signaling in recipient cells 0.5950901180857789 0.1883288615637097 0.850618861876387 1.0 1.0 2 P35222 1
Hippoyap signaling pathway 0.4272465133415834 0.1768259496007101 0.8596451053967242 1.0 1.0 3 P27348 1
Vitamin dsensitive calcium signaling in depression 0.3648891729211693 0.1758133114959126 0.8604406114756402 1.0 1.0 7 P23634,Q8NB78 2
Energy metabolism 0.3720454855252135 0.1657812133115302 0.8683291311342689 1.0 1.0 12 P49841,Q13555,Q16539,P54619 4
Folate metabolism 0.3725316191180909 0.156477396592191 0.8756567346735167 1.0 1.0 15 Q8WTV0,P34897,P01130,P00374 4
Hedgehog signaling pathway wp47 0.5730267246737136 0.156307818603814 0.8757903937365192 1.0 1.0 2 Q96ST3 1
Cholesterol biosynthesis pathway 0.367687011408367 0.1456661545907549 0.8841849410457514 1.0 1.0 13 Q15800 1
Glycogen synthesis and degradation 0.370047054910639 0.1435675446104927 0.8858419707461755 1.0 1.0 18 P49841,P30153,Q16537,Q93100 4
Apoptosis modulation and signaling 0.3588379638466048 0.1266454440384509 0.899221027359594 1.0 1.0 11 P04632 1
Glial cell differentiation 0.5413300186451322 0.1191346709756101 0.905168662870927 1.0 1.0 2 P26038 1
White fat cell differentiation 0.539465506525806 0.1172589718832898 0.9066548363736132 1.0 1.0 2 Q04726 1
Proximal tubule transport 0.355677853639655 0.116512337964428 0.9072465084123962 1.0 1.0 11 P08183,P08195 2
Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.3751942803854556 0.1075541168985959 0.914349395184836 1.0 1.0 3 Q07820,P51532 2
Exrna mechanism of action and biogenesis 0.52889993784961 0.1072517430135252 0.9145892671327492 1.0 1.0 2 Q9HAV4 1
Cell cycle 0.2816380414276575 0.1064689116737753 0.915210320072504 1.0 1.0 49 Q9UJX4,Q9Y3B8,P49841,P31946,Q04917,Q99640,Q9Y619,Q8N3U4,Q14566 9
Ccl18 signaling pathway 0.3467708732862884 0.1042242634315614 0.9169913793943684 1.0 1.0 9 P08670,P33176,P07196,P42224 4
Il17 signaling pathway 0.3370000015135738 0.1021158019990687 0.9186647583999952 1.0 1.0 4 P49841 1
Autosomal recessive osteopetrosis pathways 0.3497464401118324 0.0852360309672899 0.9320737462285204 1.0 1.0 3 O14920 1
Autophagy 0.3384502784916279 0.0807519367440985 0.935639232096175 1.0 1.0 9 Q7Z3C6,Q13131,P54619 3
Sterol regulatory elementbinding proteins srebp signaling 0.3287032345374616 0.0620605886124684 0.9505145822006535 1.0 1.0 32 Q8WTV0,Q16850,Q9HCL2 3
Mitochondrial complex i assembly model oxphos system 0.3430768139157465 0.0585767527844627 0.9532892274713488 1.0 1.0 26 Q96CU9,P51970,O95168,Q9Y6M9,O43676,P03886 6
Phosphoinositides metabolism 0.3250311332503088 0.0549866340980283 0.9561491121273074 1.0 1.0 8 Q8TBX8,Q9NTJ5,Q99570,Q9Y217,Q01968,O00443,Q13614 7
Il7 signaling pathway 0.308181091987605 0.0526327717920095 0.9580245050356851 1.0 1.0 5 P49841 1
Pilocytic astrocytoma 0.2604911408144267 0.0501073426665557 0.9600368484885478 1.0 1.0 3 P21359,Q06124 2
Cancer immunotherapy by ctla4 blockade 0.3893722809198364 0.048933778139516 0.9609720700335652 1.0 1.0 2 O00459 1
Ppar signaling pathway 0.3424457089237576 0.0472612226504301 0.9623050333697668 1.0 1.0 16 Q6P1M0,P33121,Q9UKU0,P23786 4
Notch signaling 0.3217523715621881 0.047130568562794 0.9624091642111636 1.0 1.0 8 Q92542 1
Microrna network associated with chronic lymphocytic leukemia 0.3262896208825471 0.0455143255986629 0.9636973565553516 1.0 1.0 2 Q07820 1
Fas ligand pathway and stress induction of heat shock proteins 0.3270656425929699 0.0340714977815502 0.972820136759259 1.0 1.0 11 P02545,Q03252 2
Hostpathogen interaction of human coronaviruses interferon induction 0.3039606227909643 0.0285276654118894 0.9772413031969208 1.0 1.0 6 Q16539,P42224 2
Tryptophan metabolism 0.3336939043875953 0.0250359830537485 0.9800262622699774 1.0 1.0 15 Q15392,O94788 2
Orexin receptor pathway 0.3311309884297778 0.0034258554379721 0.9972665681853145 1.0 1.0 18 P50336,P31350,Q15118,Q9P0J1 4