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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:fc648f6bff0888fff99eebb76303845b5ec8ee460309ffe804049df1cccbef72
+size 73659

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3253,
+    "annotations_size": 56,
+    "title": "Average number of proteins per term",
+    "value": 2.6607142857142856
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C210/C210_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Glycosyl hydrolases family 31, active site [IPR030458]	0.5466010458320667	0.1230317376036816	0.9020819659049332	1.0	0.9957338152815092	2	Q14697	1
+ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]	0.5047677637649997	0.06379488138998	0.9491335540176742	1.0	0.9957338152815092	2	P53597	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.4164872346970358	0.0076251913939559	0.9939160364708528	1.0	1.0	2	Q9NQ88	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "MAP3K4", "MAP3K7", "MAPK1", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCB", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRC", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TP53RK", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["GANAB", "SUCLG1", "TIGAR"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:20b1ce98883db6c51f371de0f591f458356ec638337cea2a9439a361b19c9f94
+size 72239

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3253,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.75
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C210/C210_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.7241379310344782	1.495261418516164	0.1348462299470161	0.9902952188035444	0.4315079358304515	5	Q13509,P07437,P04350,Q9BUF5	4
+EF-Hand 1, calcium-binding site [IPR018247]	0.4955388858149552	0.5850164948837385	0.5585366256795599	0.9999999999956686	0.8511034296069484	39	Q6NUK1,Q14257,Q9NWM8,P0DP25,P41208,O43852,O95202,P80303,Q9Y680	9
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.625346047370049	0.3069551978078622	0.7588774739497592	1.0	0.9233785005347456	2	O75600	1
+Peptidase M16, zinc-binding site [IPR001431]	0.4491605754676883	0.2886985183801428	0.7728120966087686	1.0	0.9233785005347456	5	P22695	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHUK", "CIT", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "MACF1", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCB", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "STK26", "STK3", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "FKBP14", "FKBP7", "GCAT", "LETM1", "NUCB2", "RCN2", "SLC25A24", "TUBB", "TUBB3", "TUBB4A", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Short-chain dehydrogenase/reductase, conserved site [IPR020904]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:574995a8ccec0da0e57fcbdf1e0ec99483cd415640efbe51ab6350a33975ff06
+size 79980

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Intermediate filament protein, conserved site [IPR018039]	7	8	3.0154347040507083	0.0025661118443818	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	7.86954941945044e-06	0.0030359610091143	0.0006140521777265	2.7013551728451183e-06	8.168214498131902e-07
+Syntaxin/epimorphin, conserved site [IPR006012]	2	6	2.9095679559663563	0.0036192869461832	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0055798171315366	0.0583291306653072	0.0065261066260236	0.0033170374819039	0.0224777557227792

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3253,
+    "annotations_size": 278,
+    "title": "Average number of proteins per term",
+    "value": 2.7302158273381294
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C210/C210_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Intermediate filament protein, conserved site [IPR018039]	0.8721109399075552	3.0154347040507083	0.0025661118443818	0.5104633594884214	0.5030808855194785	8	Q03252,P48681,P02545,Q16352,P07197,P07196,P08670	7
+Syntaxin/epimorphin, conserved site [IPR006012]	0.83953055706499	2.9095679559663563	0.0036192869461832	0.6350470983855871	0.5030808855194785	6	O60499,Q9P2W9	2
+Haem oxygenase conserved site [IPR018207]	0.952629960012306	1.66524268537536	0.0958643480716938	0.9999999999993192	0.6673184722496017	2	P30519	1
+Thioredoxin, conserved site [IPR017937]	0.5887253477987187	1.5787357018650472	0.1143966921894075	0.999999999999998	0.6673184722496017	11	Q9H3N1,Q9H1E5,Q96JJ7,O95881	4
+AMP-binding, conserved site [IPR020845]	0.5594456694663216	1.5072477250045513	0.1317471713706499	1.0	0.6673184722496017	7	Q9UKU0	1
+Tubulin, conserved site [IPR017975]	0.7241379310344782	1.495261418516164	0.1348462299470161	1.0	0.6673184722496017	5	Q13509,P07437,P04350,Q9BUF5	4
+DnaJ domain, conserved site [IPR018253]	0.5624452825776511	1.4398700720329	0.1499041617189362	1.0	0.6673184722496017	11	Q96KC8,Q9UBS4,Q9NVH1,Q9Y2G8	4
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8823900422473399	1.419930969522622	0.1556277787608535	1.0	0.6673184722496017	4	Q8N4Q0	1
+Tetraspanin, conserved site [IPR018503]	0.8877268532759192	1.3680903317891302	0.1712838026265899	1.0	0.6875566472394461	2	O43657	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.5100458872790362	1.1192145418197768	0.2630486231288516	1.0	0.7697633392612709	13	Q9BTZ2,Q53GQ0,Q06136,Q8NBN7,Q9Y394,Q6YN16	6
+4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]	0.8202130799222365	1.0431203391955786	0.29689256180272	1.0	0.7766044165502269	3	O00217	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.7843740387573068	0.9051652155191232	0.3653778667679912	1.0	0.8126003756920125	2	P13473	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7037834512457819	0.5740928258683774	0.5659049878151892	1.0	0.9584561986901066	2	P01889	1
+ABC transporter-like, conserved site [IPR017871]	0.3910780667322011	0.5294984946249567	0.5964596884409548	1.0	0.9584561986901066	11	Q03518,Q9NUT2	2
+Chaperonin TCP-1, conserved site [IPR002194]	0.3267349943583293	0.2737077981850156	0.7843091844520163	1.0	1.0	8	P48643	1
+Homeobox, conserved site [IPR017970]	0.5564441710243108	0.140787262837936	0.8880380056204102	1.0	1.0	2	P39880	1
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.5466010458320667	0.1230317376036816	0.9020819659049332	1.0	1.0	2	Q14697	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.5326169855422402	0.1013421998559649	0.919278817969573	1.0	1.0	3	O60568	1
+ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]	0.5047677637649997	0.06379488138998	0.9491335540176742	1.0	1.0	2	P53597	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.4967702245463077	0.0552711294371655	0.9559224623674224	1.0	1.0	2	P82675	1
+Ribosomal protein S2, conserved site [IPR018130]	0.4884650876653531	0.0472850991588466	0.9622860039472374	1.0	1.0	2	P08865	1
+Sugar transporter, conserved site [IPR005829]	0.4727776068902011	0.0344438086924037	0.97252324989576	1.0	1.0	2	P11166	1
+Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]	0.4617040910489143	0.0269945323005421	0.978464095035857	1.0	1.0	2	Q14155	1
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.3977237772992939	0.003437847058431	0.9972570003128348	1.0	1.0	2	Q96FJ2	1
+Actin, conserved site [IPR004001]	0.3968009843125178	0.0032737150084721	0.997387958003906	1.0	1.0	2	P61163	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDH2", "CDKAL1", "CDX2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUX1", "CYP51A1", "DBI", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FAT1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MID1", "MIF", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB8", "ACSL6", "ACTR1A", "ARHGEF7", "CCT5", "CUX1", "DHRS4", "DHRS7", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC16", "DYNLL2", "GANAB", "HLA-B", "HMOX2", "HSD17B12", "HSDL2", "INA", "KDSR", "LAMP2", "LMNA", "LMNB2", "MRPS5", "NDUFS8", "NEFL", "NEFM", "NES", "PLOD3", "RDH13", "RPSA", "SLC2A1", "STX10", "STX18", "SUCLG1", "TAP1", "TMX1", "TMX3", "TMX4", "TSPAN6", "TUBB", "TUBB3", "TUBB4A", "TUBB6", "TXNDC12", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament, rod domain [IPR039008]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament, rod domain [IPR039008]", "1": "Band 7 domain [IPR001107]", "2": "Thioredoxin domain [IPR013766]", "3": "K Homology domain, type 1 [IPR004088]", "4": "Ubiquitin-associated domain [IPR015940]", "5": "EF-hand domain [IPR002048]", "6": "Actin-depolymerising factor homology domain [IPR002108]", "7": "K Homology domain [IPR004087]", "8": "PDZ domain [IPR001478]", "9": "DnaJ domain [IPR001623]", "10": "Protein kinase, C-terminal [IPR017892]", "11": "Ubiquitin-conjugating enzyme E2 [IPR000608]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:3773c8acc5b8921f5b77245ddb1bcce12d197ce4240cb1c87e0c179fcfa2572d
+size 117753

interpro_domain/df_merge.tsv

@@ -0,0 +1,9 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Intermediate filament, rod domain [IPR039008]	7	8	3.0154347040507083	0.0025661118443818	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	2.8671896606506576e-05	0.0045302650272878	0.0011273462404087	1.001077164406324e-05	5.024242267608284e-06
+GOLD domain [IPR009038]	4	6	2.87002460001709	0.004104398659652	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.3183359929343003	1.0	1.0	1.0	0.0027426851014433
+LEM domain [IPR003887]	3	6	2.658809259225839	0.0078417344472292	2.237864077669903	5.759708737864078	0.8787481060627674	0.3228260833428172	1.2758866328838632	0.4653299410110203	1.033781091163317	0.2887768895441466	0.1620596635990733	1.0	1.0	0.1363381791325428	0.0020257428393968
+Target SNARE coiled-coil homology domain [IPR000727]	3	7	2.5238559603996245	0.0116075478341264	3.5024271844660193	8.266990291262136	0.5942034778060385	0.4012381903331891	1.9023475359698396	2.183694577914796	1.0582363712887182	0.3038263160802639	0.1632155016155889	1.0	0.2127898194125335	0.1211421538065826	0.1183493106079827
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	3	6	2.39855342031744	0.016459975372175	2.2184466019417477	6.415048543689321	0.633554567126164	0.4291196941966081	1.3185935116973673	1.1967053264777463	0.955977613408511	0.304094570424047	0.3183359929343003	1.0	1.0	0.2721697661507766	0.1285045320310699
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	3	6	2.39855342031744	0.016459975372175	2.174757281553398	6.449029126213592	0.6518715826129322	0.4280594236442204	1.299194556056103	1.212725418592039	0.9468550406660212	0.3043162658022956	0.4118317962763251	1.0	1.0	0.3559534457378639	0.2160114460330814
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	7	2.387362223777638	0.0169697621046724	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0043855039380555	0.0539630923046902	0.0055563644779973	0.0025975272437437	0.0019736987849612
+Phospholipid/glycerol acyltransferase [IPR002123]	4	7	2.3656504354435355	0.0179984294456005	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	0.0771453461761639	1.0	1.0	0.3236592382947187	0.0395358442373242

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3253,
+    "annotations_size": 2620,
+    "title": "Average number of proteins per term",
+    "value": 2.2053435114503817
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C210/C210_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,171 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Intermediate filament, rod domain [IPR039008]	0.8721109399075552	3.0154347040507083	0.0025661118443818	0.9988076797452516	0.7342495003844444	8	Q03252,P48681,P02545,Q16352,P07197,P07196,P08670	7
+GOLD domain [IPR009038]	0.8308130806163456	2.87002460001709	0.004104398659652	0.9999790977434406	0.7342495003844444	6	Q15363,P49755,Q9BVK6,Q9Y3A6	4
+LEM domain [IPR003887]	0.7850126327639082	2.658809259225839	0.0078417344472292	0.9999999988982032	0.7342495003844444	6	P42166,P42167,Q86XL3	3
+Target SNARE coiled-coil homology domain [IPR000727]	0.7607678279742582	2.5238559603996245	0.0116075478341264	0.9999999999999482	0.7342495003844444	7	O60499,Q13190,Q9UNK0	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.7302918146948971	2.39855342031744	0.016459975372175	1.0	0.7342495003844444	6	O15460,P13674,O60568	3
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.7302918146948971	2.39855342031744	0.016459975372175	1.0	0.7342495003844444	6	O15460,P13674,O60568	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7322931300364702	2.387362223777638	0.0169697621046724	1.0	0.7342495003844444	7	O43169,O00264,O15173	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7278093575140421	2.3656504354435355	0.0179984294456005	1.0	0.7342495003844444	7	O15228,Q9NUQ2,Q9HCL2,Q8NF37	4
+Band 7 domain [IPR001107]	0.6163731323949211	1.7855504012359706	0.0741720837465769	1.0	0.7342495003844444	8	Q99623,P27105,O75477,P35232,Q9UJZ1,O75955	6
+Prenylcysteine lyase [IPR010795]	0.9772377729929262	1.7777785019751635	0.0754402406385112	1.0	0.7342495003844444	2	Q8NBM8	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.9704706244232562	1.7468603226894324	0.080661569792964	1.0	0.7342495003844444	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.9704706244232562	1.7468603226894324	0.080661569792964	1.0	0.7342495003844444	2	Q13505	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7667910305190813	1.69054267111403	0.0909241818809265	1.0	0.7342495003844444	5	P05023,P16615,P98194	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.9458294859956914	1.6768921409530306	0.093563575239246	1.0	0.7342495003844444	4	P08670,P07197,P07196	3
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.5861216268540321	1.6698568029234366	0.0949476986700881	1.0	0.7342495003844444	6	Q8N4Q0	1
+Complex 1 LYR protein domain [IPR008011]	0.9381728698861942	1.599027361157682	0.109814523171092	1.0	0.7342495003844444	2	Q9Y6M9	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.933538461538458	1.5220866604495802	0.1279873679715741	1.0	0.7342495003844444	3	Q969X5,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.933538461538458	1.5220866604495802	0.1279873679715741	1.0	0.7342495003844444	3	Q969X5,Q9Y282	2
+AMP-dependent synthetase/ligase [IPR000873]	0.5594456694663216	1.5072477250045513	0.1317471713706499	1.0	0.7342495003844444	7	Q9UKU0	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.7241379310344782	1.495261418516164	0.1348462299470161	1.0	0.7342495003844444	5	Q13509,P07437,P04350,Q9BUF5	4
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.7241379310344782	1.495261418516164	0.1348462299470161	1.0	0.7342495003844444	5	Q13509,P07437,P04350,Q9BUF5	4
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.9037219317133216	1.441220830530778	0.1495223052911676	1.0	0.7401563551301782	2	Q5T9A4	1
+SUN coiled coil domain 2 [IPR040994]	0.8948015995078507	1.4004172825306611	0.1613883976522725	1.0	0.7401563551301782	2	Q9UH99	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.894186404183333	1.3976049033053335	0.1622317451150992	1.0	0.7401563551301782	2	P98179	1
+Reticulon [IPR003388]	0.9006617914481445	1.3823852542051052	0.1668534413161015	1.0	0.7497061162468496	3	Q9NQC3	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5434207020950541	1.379689197587572	0.1676823603513946	1.0	0.7497061162468496	9	Q9NWM8	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8834204860043102	1.3484314575549488	0.1775196518606818	1.0	0.7671387483967292	2	O15460	1
+LEM-like domain [IPR013146]	0.8772685327591582	1.3203756509364122	0.1867096289680094	1.0	0.7793903564146855	2	P42167	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8562949383596765	1.3138169299943765	0.1889078188717978	1.0	0.7793903564146855	4	Q15629,Q96G23	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.5240881318323587	1.296523333217454	0.1947952465861195	1.0	0.7863794751851636	8	Q03518,Q9NUT2	2
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6788119790356475	1.2856916887611418	0.198550682988486	1.0	0.789907586722882	5	Q9UKU0	1
+Dynamin, N-terminal [IPR045063]	0.5165303718767911	1.2765300072743186	0.2017682262877151	1.0	0.7983142884788442	7	O60313,Q8IWA4	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5165303718767911	1.2765300072743186	0.2017682262877151	1.0	0.7983142884788442	7	O60313,Q8IWA4	2
+Lamin tail domain [IPR001322]	0.8707692307692251	1.2556023461466717	0.209260180330264	1.0	0.8086247909829376	3	Q03252,P02545	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8413069229471317	1.2528867529207897	0.2102469235432273	1.0	0.8086247909829376	4	P98194,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8413069229471317	1.2528867529207897	0.2102469235432273	1.0	0.8086247909829376	4	P98194,P16615	2
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.8600430636727157	1.242040457558515	0.2142216352971022	1.0	0.8086247909829376	2	P16435	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.8600430636727157	1.242040457558515	0.2142216352971022	1.0	0.8086247909829376	2	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.8600430636727157	1.242040457558515	0.2142216352971022	1.0	0.8086247909829376	2	P16435	1
+tRNA synthetases class I, catalytic domain [IPR032678]	0.8532759151030529	1.21137571312417	0.2257514431103491	1.0	0.8144235784615498	2	P49589	1
+Tim10-like [IPR004217]	0.8498923408182183	1.1960708053195763	0.2316689293385561	1.0	0.824891744734037	2	Q9Y5J9	1
+FAD dependent oxidoreductase [IPR006076]	0.8193746106020117	1.163879646263964	0.2444727891139528	1.0	0.8328871561493322	4	Q9H9P8	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8412796062749937	1.1572048430725568	0.2471886795259514	1.0	0.8335062295469664	2	O60506	1
+AP complex, mu/sigma subunit [IPR022775]	0.4937583072800313	1.1529355605469036	0.2489368347984375	1.0	0.8340338966392665	7	P48444	1
+Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+VPS13, repeated coiled region [IPR031642]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+Autophagy-related, C-terminal [IPR015412]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.8323592740695165	1.1171067094288205	0.2639487020925415	1.0	0.8433482920517789	2	Q709C8	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.8298984927714652	1.1060760509330274	0.2686936036042968	1.0	0.8512421299192959	2	Q9HCL2	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.8298984927714652	1.1060760509330274	0.2686936036042968	1.0	0.8512421299192959	2	Q9HCL2	1
+Zinc finger, CHHC-type [IPR012996]	0.8350769230769154	1.1052086872949556	0.2690691734420962	1.0	0.851402457026923	3	P52597,P31943	2
+NOPS [IPR012975]	0.8310769230769147	1.0884614803139503	0.2763914326588446	1.0	0.8596297637916859	3	P23246,Q8WXF1	2
+CBS domain [IPR000644]	0.4726050155972329	1.0378179979381337	0.2993547960501712	1.0	0.8646775616482824	7	P54619,P12268,Q6P4Q7,Q8NE01	4
+NAD(P)-binding domain [IPR016040]	0.8071362657643899	1.004788689762833	0.3149986111425891	1.0	0.8650230055268721	2	Q8NBZ7	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8055982774530955	0.9979996649334064	0.3182795211201881	1.0	0.8650230055268721	2	Q92945	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8049230769230713	0.9797193334638457	0.3272246800381833	1.0	0.8727397965343892	3	O15460,P13674	2
+PDZ domain 6 [IPR041489]	0.7966153846153756	0.9455078727005004	0.3443996534727427	1.0	0.8775782074898457	3	Q92614,O43464	2
+Acyltransferase, C-terminal domain [IPR032098]	0.7908335896647231	0.9332394902149684	0.3506963294816292	1.0	0.8775782074898457	2	Q9NUQ2	1
+Glycosyl transferase, family 1 [IPR001296]	0.7870769230769137	0.906464768649813	0.3646899045136762	1.0	0.8917899424629027	3	Q2TAA5,Q9BT22	2
+Tudor domain [IPR002999]	0.4505428474742813	0.897957257671107	0.3692083370428092	1.0	0.8917899424629027	8	Q9Y2W6	1
+MIT domain [IPR007330]	0.7842766291583597	0.8950547349033685	0.3707578293856064	1.0	0.8917899424629027	3	Q6PHR2	1
+Cold-shock (CSD) domain [IPR019844]	0.7505777373826592	0.8880681127120541	0.3745041138862088	1.0	0.8917899424629027	4	P67809	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.7754650407578305	0.8593190182571817	0.390164534404811	1.0	0.8944425354519228	3	Q06323	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.7754650407578305	0.8593190182571817	0.390164534404811	1.0	0.8944425354519228	3	Q06323	1
+KASH domain [IPR012315]	0.7717625346047359	0.850868077496851	0.3948426394701521	1.0	0.8944425354519228	2	Q8WXH0	1
+HECT domain [IPR000569]	0.4488925547747504	0.8498130192228643	0.3954290501663249	1.0	0.8944425354519228	10	P46934	1
+CARG-binding factor, N-terminal [IPR012956]	0.7653029836973244	0.823346150284952	0.4103111763554341	1.0	0.9048950185616476	2	Q14103	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.7142915498376154	0.7467774738107328	0.4551978952133058	1.0	0.9462928780830774	4	O00217	1
+SUN domain [IPR012919]	0.7457515982398526	0.7410060594757039	0.4586897662857376	1.0	0.9477899964005404	3	Q9UH99	1
+Peptidase M16, C-terminal [IPR007863]	0.4165631995706408	0.734984365460849	0.4623490159261045	1.0	0.9493373211021896	7	Q5JRX3,P22695,Q10713	3
+Peptidase M16, N-terminal [IPR011765]	0.4165631995706408	0.734984365460849	0.4623490159261045	1.0	0.9493373211021896	7	Q5JRX3,P22695,Q10713	3
+Mab-21 domain [IPR024810]	0.7416179637034761	0.7243695799763659	0.4688388703277675	1.0	0.953693975356173	2	Q8IWB1	1
+Thioredoxin domain [IPR013766]	0.4681579823567743	0.7113750419576939	0.4768518607438254	1.0	0.963396758218356	23	Q9H3N1,Q9H1E5,Q6ZRP7,Q9Y2G8,O95881,Q96JJ7	6
+C2 DOCK-type domain [IPR027007]	0.7379267917563902	0.7092502280771655	0.478169208905288	1.0	0.9636632822575046	2	Q14185	1
+DOCKER domain [IPR027357]	0.7379267917563902	0.7092502280771655	0.478169208905288	1.0	0.9636632822575046	2	Q14185	1
+Cold-shock protein, DNA-binding [IPR002059]	0.5459917282688457	0.6782873662750102	0.4975895074535945	1.0	0.9835710303688548	5	P67809	1
+Cold shock domain [IPR011129]	0.5459917282688457	0.6782873662750102	0.4975895074535945	1.0	0.9835710303688548	5	P67809	1
+Peptidase M41 [IPR000642]	0.7293140572131728	0.6743290815246773	0.5001021190122206	1.0	0.9835710303688548	2	Q9Y4W6	1
+EB1, C-terminal [IPR004953]	0.7262380805905948	0.6619840718441261	0.5079814297774627	1.0	0.9844018831486336	2	Q15555	1
+K Homology domain, type 1 [IPR004088]	0.4542056201308082	0.6576549519069194	0.510759875242077	1.0	0.9868664256152224	22	Q15637,P61978,Q9Y2W6,Q9Y6M1,Q96I24,Q92945,Q96AE4,Q8TCS8	8
+Heat shock chaperonin-binding [IPR006636]	0.5358741746482283	0.6341282159397619	0.525997149989379	1.0	0.9910063791221768	5	Q9BSL1,Q9NRR5,P54725	3
+Chaperone DnaJ, C-terminal [IPR002939]	0.5322579808385461	0.6184846231585497	0.5362559308789783	1.0	0.9991460818066196	5	Q9UBS4	1
+Ubiquitin-associated domain [IPR015940]	0.4109484878266	0.612781274636169	0.5400209739620379	1.0	0.9991460818066196	12	P54725,Q9Y5A7,Q5T6F2,P45974,Q9NRR5,Q9UPU5	6
+WW domain [IPR001202]	0.4176477970324571	0.6114571879310065	0.5408969527243077	1.0	0.9991460818066196	14	P46934	1
+CNNM, transmembrane domain [IPR002550]	0.7111657951399657	0.6025346253603359	0.546818322043551	1.0	1.0	2	Q6P4Q7	1
+Ion transporter-like, CBS domain [IPR044751]	0.7111657951399657	0.6025346253603359	0.546818322043551	1.0	1.0	2	Q6P4Q7	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7048926547896337	0.5855374006626111	0.5581864260836982	1.0	1.0	3	P10321	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7048926547896337	0.5855374006626111	0.5581864260836982	1.0	1.0	3	P10321	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7048926547896337	0.5855374006626111	0.5581864260836982	1.0	1.0	3	P10321	1
+Immunoglobulin C1-set [IPR003597]	0.7048926547896337	0.5855374006626111	0.5581864260836982	1.0	1.0	3	P10321	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3910780667322011	0.5294984946249567	0.5964596884409548	1.0	1.0	11	Q03518,Q9NUT2	2
+Chromo shadow domain [IPR008251]	0.6881799308620723	0.5250587756080815	0.5995423327323679	1.0	1.0	3	P45973	1
+Chromo domain subgroup [IPR017984]	0.6881799308620723	0.5250587756080815	0.5995423327323679	1.0	1.0	3	P45973	1
+EF-hand domain [IPR002048]	0.4986067922993234	0.4807300485362727	0.6307083720183255	1.0	1.0	47	Q9BRK5,Q14257,Q9NWM8,O95202,Q8NF37,Q9UBV8,Q8IYU8,Q96D71,P0DP25,P41208,Q9Y680,P04632,O75071,O75746,Q6KCM7,Q6NUK1,O43852,Q66K14,P80303	19
+Diacylglycerol/phorbol-ester binding [IPR020454]	0.6779452476161264	0.478507890029068	0.6322887599371321	1.0	1.0	2	P05771	1
+Myosin tail [IPR002928]	0.6377346875961866	0.4678132049093415	0.6399181766594242	1.0	1.0	4	P35579,Q92614,P35580	3
+LRRC8, pannexin-like TM region [IPR021040]	0.6677945247616168	0.4428222736366627	0.6578942912182852	1.0	1.0	2	Q8TDW0	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6633846153846215	0.4394490586080463	0.6603361858625836	1.0	1.0	3	Q9BSJ8,Q8NEN9	2
+Actin-depolymerising factor homology domain [IPR002108]	0.3570548367221122	0.4295354564794009	0.6675335965243683	1.0	1.0	7	Q9Y281,P23528,Q12792,Q16643,Q14019,P60983	6
+Extended synaptotagmin, C2B domain [IPR037749]	0.6631805598277506	0.4269809364763264	0.6693932129137405	1.0	1.0	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6631805598277506	0.4269809364763264	0.6693932129137405	1.0	1.0	2	Q9BSJ8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.6631805598277506	0.4269809364763264	0.6693932129137405	1.0	1.0	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6631805598277506	0.4269809364763264	0.6693932129137405	1.0	1.0	2	Q9BSJ8	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.3474527134460503	0.3997863709824813	0.6893138698776056	1.0	1.0	6	Q8WUK0,Q99956	2
+K Homology domain [IPR004087]	0.4006457824105092	0.3964546308764949	0.6917696709572454	1.0	1.0	22	Q15637,P61978,Q9Y2W6,Q9Y6M1,Q96I24,Q92945,Q96AE4,Q8TCS8	8
+Immunoglobulin-like domain [IPR007110]	0.3699326983750722	0.3932751797675323	0.6941162480727006	1.0	1.0	13	Q9Y639,P10321,P01889,Q08722	4
+Tim44-like domain [IPR007379]	0.647800676714867	0.3759929337580784	0.7069221492890749	1.0	1.0	2	O43615	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.6058148076538374	0.3632320207513146	0.7164315696593111	1.0	1.0	4	P50416,Q9UKG9	2
+Nuclear transport factor 2, eukaryote [IPR018222]	0.6360000000000015	0.3515801109070548	0.7251531832602451	1.0	1.0	3	Q13283,Q9UBU9	2
+Nuclear transport factor 2 domain [IPR002075]	0.6360000000000015	0.3515801109070548	0.7251531832602451	1.0	1.0	3	Q13283,Q9UBU9	2
+PDZ domain [IPR001478]	0.3831105386186333	0.3465031252013466	0.7289646359470838	1.0	1.0	20	Q9NRD5,Q92614,O00560,O43464,Q96RT1,Q8NEN9,P57105	7
+DnaJ domain [IPR001623]	0.3733869289048011	0.3324918503105221	0.7395178925295065	1.0	1.0	18	Q96KC8,Q9NVH1,Q9UGP8,Q9Y2G8,Q9UBS4	5
+Mst1 SARAH domain [IPR024205]	0.6204244847739249	0.2927385007256575	0.7697220390415169	1.0	1.0	2	Q13188	1
+SARAH domain [IPR011524]	0.6204244847739249	0.2927385007256575	0.7697220390415169	1.0	1.0	2	Q13188	1
+Dynamin, GTPase domain [IPR001401]	0.612151352498626	0.2816693859087215	0.7781970308940354	1.0	1.0	3	O60313	1
+Zinc finger, RanBP2-type [IPR001876]	0.329708060389195	0.2720549410844834	0.7855797749959246	1.0	1.0	9	Q01844,Q92804	2
+AGC-kinase, C-terminal [IPR000961]	0.3292555206008116	0.2557576232830562	0.7981379975007774	1.0	1.0	10	P05771,P31751,O75116	3
+Ubiquitin system component CUE [IPR003892]	0.5932307692307708	0.2310912966368363	0.8172438764216636	1.0	1.0	3	Q9Y679,Q9H1I8	2
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3125547785854188	0.2276525618509618	0.8199163541989081	1.0	1.0	7	O15372,Q92905,Q7L5N1	3
+Glycosyl transferase CAP10 domain [IPR006598]	0.5936634881575013	0.2215820975512437	0.8246392201578583	1.0	1.0	2	Q7Z4H8	1
+Protein kinase, C-terminal [IPR017892]	0.3024330150908532	0.1999336649913773	0.8415324611068544	1.0	1.0	6	Q16513,P31751,Q15418,P05771,P51812	5
+Extended PHD (ePHD) domain [IPR034732]	0.5803113865891445	0.1992137972712434	0.8420955070689538	1.0	1.0	3	O95696	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4181034482758511	0.1863983808372231	0.8521323620848762	1.0	1.0	5	P62333,P62191,P43686,P62195	4
+Man1/Src1, C-terminal [IPR018996]	0.5699784681636554	0.1676675989348528	0.8668447875867789	1.0	1.0	2	Q9Y2U8	1
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.5603076923076922	0.1543100712989504	0.8773652566809302	1.0	1.0	3	Q9UPN9,Q13049	2
+Domain of unknown function DUF625 [IPR006887]	0.5555213780375409	0.139058740319933	0.8894037318314365	1.0	1.0	2	Q6IN85	1
+Glycoside hydrolase family 31, N-terminal domain [IPR025887]	0.5466010458320667	0.1230317376036816	0.9020819659049332	1.0	1.0	2	Q14697	1
+EF-hand, Ca insensitive [IPR014837]	0.5369230769230829	0.1088731142822836	0.9133031315523514	1.0	1.0	3	Q13813,O43707	2
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.2898567495810724	0.1040581871488615	0.9171231724808342	1.0	1.0	10	Q8NEN9,P05771,O75116	3
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.5326169855422402	0.1013421998559649	0.919278817969573	1.0	1.0	3	O60568	1
+Potentiating neddylation domain [IPR005176]	0.5035506404860125	0.1007405794548342	0.919756397467912	1.0	1.0	4	Q92564	1
+SKP1 component, POZ domain [IPR016073]	0.5321439557059531	0.0996508190596398	0.920621546807914	1.0	1.0	2	P63208	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.5318363580436924	0.0991876640485586	0.9209892692208712	1.0	1.0	2	Q8TAQ2	1
+SMARCC, N-terminal [IPR032450]	0.5318363580436924	0.0991876640485586	0.9209892692208712	1.0	1.0	2	Q8TAQ2	1
+SMARCC, C-terminal [IPR032451]	0.5318363580436924	0.0991876640485586	0.9209892692208712	1.0	1.0	2	Q8TAQ2	1
+GRIP domain [IPR000237]	0.5250692094740145	0.0893531733934008	0.9288012367687272	1.0	1.0	2	Q8IWJ2	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.4918436441982193	0.0791434546135066	0.9369185201068292	1.0	1.0	4	O60749,Q9UNH7,Q9Y5X3	3
+GAR domain [IPR003108]	0.508458935712107	0.0680154558286141	0.9457733308039686	1.0	1.0	2	Q03001	1
+Sec7 domain [IPR000904]	0.5075361427253336	0.0669430229842921	0.9466270624465916	1.0	1.0	2	Q9Y6D6	1
+CoA-binding [IPR003781]	0.5047677637649997	0.06379488138998	0.9491335540176742	1.0	1.0	2	P53597	1
+MIRO domain [IPR020860]	0.5013841894801693	0.060086321548031	0.9520868841022978	1.0	1.0	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.5013841894801693	0.060086321548031	0.9520868841022978	1.0	1.0	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.5013841894801693	0.060086321548031	0.9520868841022978	1.0	1.0	2	Q8IXI1	1
+Exosome complex component, N-terminal domain [IPR025721]	0.4980006151953436	0.0565282334425513	0.9549210044440172	1.0	1.0	2	Q13868	1
+PABP, RNA recognition motif 2 [IPR045305]	0.497077822208569	0.0555835835472243	0.9556735427163444	1.0	1.0	2	P11940	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.4967702245463077	0.0552711294371655	0.9559224623674224	1.0	1.0	2	P82675	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.4967702245463077	0.0552711294371655	0.9559224623674224	1.0	1.0	2	P82675	1
+Sorting nexin, N-terminal [IPR005329]	0.4915410642879214	0.0501428236749785	0.9600085742818584	1.0	1.0	2	O60749	1
+Cyclin, N-terminal [IPR006671]	0.4866195016917963	0.0456257238856762	0.963608565822592	1.0	1.0	2	P24863	1
+Peptidase C14,  p20 domain [IPR001309]	0.483851122731474	0.0432130058039859	0.965531737641455	1.0	1.0	2	Q9UDY8	1
+FAST kinase leucine-rich [IPR010622]	0.480159950784379	0.0401357531015746	0.9679848979022818	1.0	1.0	2	Q969Z0	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.480159950784379	0.0401357531015746	0.9679848979022818	1.0	1.0	2	Q969Z0	1
+RAP domain [IPR013584]	0.480159950784379	0.0401357531015746	0.9679848979022818	1.0	1.0	2	Q969Z0	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.2643463158430312	0.0348188452015664	0.9722241934444024	1.0	1.0	9	O43708,Q9H7Z7,Q8TB36	3
+Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]	0.4660104583205195	0.0297425253817992	0.9762723965602635	1.0	1.0	2	P61011	1
+Signal recognition particle SRP54, helical bundle [IPR013822]	0.4660104583205195	0.0297425253817992	0.9762723965602635	1.0	1.0	2	P61011	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.4644724700092351	0.0287398830904048	0.9770720473880744	1.0	1.0	2	O75694	1
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.4543217471547419	0.0227000201743212	0.9818895597439092	1.0	1.0	2	Q9BQ67	1
+Dual specificity protein phosphatase domain [IPR020422]	0.4705799545479013	0.0204830001179969	0.9836580731731212	1.0	1.0	3	Q99956	1
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.4705799545479013	0.0204830001179969	0.9836580731731212	1.0	1.0	3	Q99956	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.4146416487234701	0.0071342529685112	0.9943077379906502	1.0	1.0	2	P42695	1
+ZU5 domain [IPR000906]	0.398954167948332	0.0036622033049277	0.9970779910560124	1.0	1.0	2	Q12955	1
+Ubiquitin-conjugating enzyme E2 [IPR000608]	0.2524660912453806	0.0032840413574136	0.9973797188138064	1.0	1.0	9	Q9NR09,P49427,P61081,P61088,Q16763,P68036,Q9C0C9,Q9Y385	8
+eRF1 domain 3 [IPR005142]	0.3943402030144603	0.0028528992672015	0.9977237188089628	1.0	1.0	2	Q9BRX2	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.3943402030144603	0.0028528992672015	0.9977237188089628	1.0	1.0	2	Q9BRX2	1
+eRF1 domain 2 [IPR005141]	0.3943402030144603	0.0028528992672015	0.9977237188089628	1.0	1.0	2	Q9BRX2	1
+Zinc finger, TFIIB-type [IPR013137]	0.3891110427560808	0.0020361045699831	0.9983754247219364	1.0	1.0	2	P29083	1
+Putative WW-binding domain and destruction box [IPR033461]	0.3838818824976997	0.0013166850582519	0.998949437624134	1.0	1.0	2	Q9ULX3	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]"}