diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7602e0570c87b5ab1a013e47edea39bde84da31b --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4589561a00b7947d535277ceb76bf05f63648430f31719f07aea671e7bb7b1eb +size 76325 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1f287df98b488ee653632d64e43ae68829478ef2 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 56, + "title": "Average number of proteins per term", + "value": 2.6607142857142856 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..14671eacf78aa7710dd4a2e8f417a50c4756320d --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d520613cfd008eca9643275a2b574acd736b4ea --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9775315481686676 1.7041173067226685 0.0883591739622728 0.994374891624957 0.3092571088679551 3 P10619,Q9HB40 2 +Histidine acid phosphatase active site [IPR033379] 0.9366153846153832 0.9509106090140654 0.3416497558239171 0.9999999999318302 0.7086069009681244 2 Q9NPH0 1 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.4990710735031813 0.7216883278655708 0.4704861198837085 0.9999999999999996 0.7749183151025787 6 Q16763,P61088,P49427 3 +Peptidase S9, serine active site [IPR002471] 0.4950769230769256 0.0468661429744753 0.9626199124212618 1.0 0.9909325085941092 2 P13798 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.3551862111418943 0.0282615562415483 0.977453542018359 1.0 0.9909325085941092 3 P22314,Q8TBC4 2 +Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.2865497076023441 0.019297378119199 0.98460387549804 1.0 0.9909325085941092 3 Q16881,P00390 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2a62ef4b7bf535cd33906522801d0338e106be0d --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "MAP3K4", "MAP3K7", "MAPK1", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCB", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRC", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TP53RK", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "APEH", "CDC34", "CTSA", "GSR", "SCPEP1", "TXNRD1", "UBA1", "UBA3", "UBE2N", "UBE2S"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..23cf9617929b49f80e64d5daf6f797ff61f6f934 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ce3b94b4db8f060a6ca9046c2205b8068fb7f893938b9484f15c8f9f1049a1f +size 142503 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8f214079f1649218068de7915a01519b6f3e8fa0 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff55f5a5bc54f27aa3703229337758ec1362eff593184ae8e6305053096afb84 +size 73687 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..570e9f78913ec6c43ab51f2fc89c63688d178e77 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 32, + "title": "Average number of proteins per term", + "value": 4.75 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b46aecb74e34cab373c7cb1d27a681caff7d4231 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..760d9b3ead0404ced10039751a5050e3b81cb8c2 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M16, zinc-binding site [IPR001431] 0.7500207753160685 1.6622581406614505 0.096461026948988 0.9610685587191626 0.4409646946239454 5 Q10713,O43847 2 +Beta tubulin, autoregulation binding site [IPR013838] 0.6471144881000066 1.219244243142241 0.2227515040706205 0.9996852856906852 0.5483113946353735 5 P04350,Q9BUF5,Q13509 3 +EF-Hand 1, calcium-binding site [IPR018247] 0.3942640338525817 0.9798630766354356 0.3271537111617286 0.9999968860791946 0.6979279171450211 39 P80303,Q14257,Q9H4M9,P30626,Q14651,Q9NWM8,P0DP25,Q02818,Q9Y680,O43852 10 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6732307692307704 0.2244412599085255 0.8224139687108649 1.0 0.9265981279297724 2 O15270 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a33c20e1915f7b2f0ee9eaa00972d7b662e4f672 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "CHUK", "CIT", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "MACF1", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCB", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "STK26", "STK3", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CALM3", "CALU", "EHD1", "FKBP14", "FKBP7", "NRDC", "NUCB1", "NUCB2", "PLS1", "PMPCA", "RCN2", "SPTLC2", "SRI", "TUBB3", "TUBB4A", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0b9bbc0dc52433ecdf0b1249a61504387474e680 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "DnaJ domain, conserved site [IPR018253]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..315d534e9d394cb4cd3ad6889e8dfdab0ab00d51 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da23070c152789f2298a7a87ea44abaa58e6ec4ab8bc3fb3cc3d9b8aa0043b65 +size 142239 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0455fd275f0173c518d465776187da6d1ff42f9a --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1524421eb084e3023c7a72af2d8fe37c2039767aa744ea5d628084b1e26acc1 +size 83101 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ac8c24a3cd6f9a2b4353db7fe9d57d9758c139df --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 4 8 2.011419511810239 0.0442811641003138 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0006940358493172 0.0470522829573702 0.0039921150854813 0.0015206572897169 5.650922597265324e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..db68a584dcacaaea342b389d0c4968dfe0fcf8e5 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 278, + "title": "Average number of proteins per term", + "value": 2.7302158273381294 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..eeaf46080060c1c9849d67df8fb520446b7e1c0c --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f99cc13cc4d5409a52caa1fba53d1d9ab2563835 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,40 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8949321187617436 2.113039828885418 0.0345973590328152 0.9999439006088752 0.4649907911516787 4 Q99536,Q8N4Q0 2 +Proteasome beta-type subunit, conserved site [IPR016050] 0.7836506869700209 2.011419511810239 0.0442811641003138 0.9999965976386848 0.4649907911516787 8 P49721,P20618,P28070,P28072 4 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8603626122065793 1.9728272463127532 0.0485152478193291 0.9999990098304437 0.4649907911516787 4 P48735 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.779906685083386 1.950659524128685 0.0510975612820838 0.9999995348484676 0.4649907911516787 6 O60499,Q13190 2 +Clathrin adaptor complex, small chain [IPR000804] 0.728372169486873 1.423302605206601 0.1546484520971505 1.0 0.5889352011370937 4 P61966 1 +Tubulin, conserved site [IPR017975] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.6795599610801132 5 P04350,Q9BUF5,Q13509 3 +Ras GTPase-activating protein, conserved site [IPR023152] 0.6686083832710072 1.1707086142791991 0.2417159214664783 1.0 0.7073371175545367 4 Q86VI3 1 +Tetraspanin, conserved site [IPR018503] 0.9864615384615384 1.1215086267211023 0.2620714215346917 1.0 0.7148276006344034 2 O43657 1 +Haem oxygenase conserved site [IPR018207] 0.9741538461538436 1.078993888763519 0.2805904519777957 1.0 0.7148276006344034 2 P30519 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9587692307692312 1.0261828354275997 0.304805410514922 1.0 0.7148276006344034 2 Q9BTY2 1 +Glycoside hydrolase, family 35, conserved site [IPR019801] 0.9492307692307648 0.993652058121697 0.3203922905292411 1.0 0.7148276006344034 2 Q8IW92 1 +EGF-like calcium-binding, conserved site [IPR018097] 0.7756232686980628 0.9388875846934616 0.347788464183173 1.0 0.7148276006344034 3 Q14517,Q04721 2 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.7148276006344034 2 P05067 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.7148276006344034 2 P05067 1 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.7148276006344034 2 P05067 1 +Thioredoxin, conserved site [IPR017937] 0.5315656882257062 0.9095780385958504 0.3630450848600026 1.0 0.7148276006344034 11 O95881,Q9H1E5 2 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9236923076923036 0.9075009456658516 0.3641419496264624 1.0 0.7148276006344034 2 P13473 1 +ABC transporter-like, conserved site [IPR017871] 0.5251191283230592 0.8788341378261035 0.3794912136266088 1.0 0.7183153819742129 11 P33527,Q9NUT2,P08183 3 +Heat shock protein Hsp90, conserved site [IPR019805] 0.7533253622836772 0.8573425104882835 0.3912556212316798 1.0 0.7349260993405877 3 P08238 1 +Ubiquitin interacting motif [IPR003903] 0.5534474109545262 0.69736160236767 0.4855765250967463 1.0 0.8244088084314432 4 Q9Y6I3 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8516923076922992 0.6749342908330294 0.4997175131615239 1.0 0.8345667257421252 2 P01889 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.672822406894432 0.5785520411787655 0.5628914729357894 1.0 0.8941933112922827 3 O15347,P26583 2 +EGF-like, conserved site [IPR013032] 0.7753846153846129 0.4542418382412121 0.649654772929614 1.0 0.98690725067996 2 Q04721 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.996876762152501 6 P33993 1 +DnaJ domain, conserved site [IPR018253] 0.4209999938929812 0.4088675866713286 0.6826368371253086 1.0 0.996876762152501 11 P25685,Q9NXW2,Q96EY1,Q9NVH1,Q9UBS4 5 +Profilin conserved site [IPR027310] 0.7418461538461578 0.3692071912179709 0.7119732961446585 1.0 0.996876762152501 2 P07737 1 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.7276923076923058 0.3359668969371918 0.7368958294050554 1.0 0.996876762152501 2 Q96FJ2 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.7252307692307735 0.3303564980572543 0.7411306075543065 1.0 0.996876762152501 2 P50570 1 +AMP-binding, conserved site [IPR020845] 0.3932797351473825 0.3039504137508357 0.7611656689612065 1.0 0.9981323394868652 7 Q9UKU0 1 +Annexin repeat, conserved site [IPR018252] 0.4099788468673957 0.2818686820521908 0.7780442043425002 1.0 0.9991344085504752 5 P50995,P04083 2 +Guanylate kinase, conserved site [IPR020590] 0.397312577448684 0.1929225093019883 0.8470196563039933 1.0 1.0 4 Q9NZW5 1 +Ribosomal protein S2, conserved site [IPR018130] 0.6033846153846214 0.1223843981649246 0.9025945940848974 1.0 1.0 2 Q9Y399 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4465989535241663 0.0794191829286176 0.9366992110626224 1.0 1.0 3 O60568,O00469 2 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.5086153846153935 0.0519698111248363 0.9585527481277774 1.0 1.0 2 P29692 1 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.5012307692307822 0.0490668272065001 0.9608660396048077 1.0 1.0 2 P06737 1 +Vinculin, conserved site [IPR000633] 0.4978461538461645 0.0478326600098225 0.9618496074138684 1.0 1.0 2 P35221 1 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.4326153846153812 0.0333158050051984 0.973422750184684 1.0 1.0 2 Q14155 1 +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.2735384615384519 0.0283235546274284 0.9774040942581316 1.0 1.0 2 P14174 1 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9f40f591a8c5d7e02c0fce6ea0d75fc4b6e6a73a --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDH2", "CDKAL1", "CDX2", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUX1", "CYP51A1", "DBI", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FAT1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MID1", "MIF", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ACSL6", "ANXA1", "ANXA11", "AP1S1", "APP", "ARHGEF7", "CTNNA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC11", "DNM2", "DYNLL2", "EEF1D", "EPN1", "FAT1", "FUCA2", "GLB1L2", "HLA-B", "HMGB2", "HMGB3", "HMOX2", "HSP90AB1", "IDH2", "IQGAP3", "LAMP2", "MCM7", "MIF", "MPP6", "MRPS2", "NOTCH2", "PFN1", "PLOD2", "PLOD3", "POLR2B", "POLR3B", "PSMB1", "PSMB2", "PSMB4", "PSMB6", "PYGL", "STX10", "STX5", "TMX4", "TSPAN6", "TUBB3", "TUBB4A", "TUBB6", "TXNDC12", "VAT1", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6316fe6bb14f609cfa438ddfb41f5e3caa7711ed --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "K Homology domain, type 1 [IPR004088]", "1": "Immunoglobulin-like domain [IPR007110]", "2": "EF-hand domain [IPR002048]", "3": "K Homology domain [IPR004087]", "4": "RNA recognition motif domain, eukaryote [IPR003954]", "5": "SH3 domain [IPR001452]", "6": "Ubiquitin-like domain [IPR000626]", "7": "THIF-type NAD/FAD binding fold [IPR000594]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f2f2ff90ec132db53d9534dedd1797cc75d4e874 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ 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@@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b90aece5143921ec28dfe042ec18ba6be1f26823fd66cdb6e0a2005a7660dd13 +size 147179 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..85271c1f8badb45d73098d7b44e370a5075abdd8 --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d834142ae8298088b2d92e6872c2be27fdd79c65c0b55fd07e601da0a56628c2 +size 145008 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e6a972449c2854fec5b39bcc26fedfda3966dff1 --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1221085ddea55f94692a85f30f5512c3a72eb595f57cd601a2245f6cd8443098 +size 123460 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7947c4c0aded9358737a26f01c83ae3e8e2a4218 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdd88016d0a11e4cd7da741ed19e7394ff3ca14e1331c87780301a02f02166f8 +size 187435 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..57cb10f4e88cef464b52b867a7e7a1dbfca16e40 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Aminopeptidase N-like , N-terminal domain [IPR045357] 4 6 2.4720646689753 0.0134335213238978 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0003329397892747 0.0378187125466048 0.0025156479029566 2.2502069418558096e-05 1.3632546196600551e-05 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 4 6 2.4720646689753 0.0134335213238978 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0003329397892747 0.0378187125466048 0.0025156479029566 2.2502069418558096e-05 1.3632546196600551e-05 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a34e764391218162f0b2ff5142c3773547b6220f --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 2620, + "title": "Average number of proteins per term", + "value": 2.2053435114503817 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..33d5474f2b342cdff9c98e5b8f145143712210fe --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..84d3751e989a59f1bde834b7a21db6f3d9ce2c2d --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,244 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.9069167935981328 2.4720646689752996 0.0134335213238978 0.9999999999999996 0.4573257640128652 6 P09960,Q9UIQ6,P55786,Q9NZ08 4 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.9069167935981328 2.4720646689752996 0.0134335213238978 0.9999999999999996 0.4573257640128652 6 P09960,Q9UIQ6,P55786,Q9NZ08 4 +ERAP1-like C-terminal domain [IPR024571] 0.9104064039408852 2.1752062960115257 0.0296146605921621 1.0 0.4573257640128652 4 Q9UIQ6,P55786,Q9NZ08 3 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.8603626122065793 1.9728272463127532 0.0485152478193291 1.0 0.4578907167881412 4 P48735 1 +Heat shock chaperonin-binding [IPR006636] 0.801627483846849 1.8800308994114656 0.0601038668525384 1.0 0.4743900239127562 5 Q9BSL1,P54725,P54727 3 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8286528931414507 1.8426763068245815 0.0653762853369608 1.0 0.4811400774798802 4 Q96CP7,Q15629 2 +Potentiating neddylation domain [IPR005176] 0.8102431405434726 1.766490796742742 0.0773135442394765 1.0 0.5051408626120414 4 Q8IWE4,Q92564 2 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7316541460748515 1.744536997409853 0.0810654958970755 1.0 0.508327248444144 6 Q99536,Q8N4Q0 2 +Amine oxidase [IPR002937] 0.7938158427696818 1.6981561830717409 0.089478287999829 1.0 0.522222444568061 4 Q6QHF9 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.6963762144563895 1.6073908455508727 0.1079686569883426 1.0 0.5609301898435118 7 O60499,Q13190 2 +EGF-like domain [IPR000742] 0.759059523579367 1.5526231203087817 0.1205131988145056 1.0 0.5814817327698061 4 Q14517,Q04721 2 +Cold-shock (CSD) domain [IPR019844] 0.7526943632330918 1.5258519363297114 0.1270467428945343 1.0 0.5912299580527175 4 P67809,Q9Y2V2 2 +Peptidase M16, C-terminal [IPR007863] 0.6669740023530372 1.4765126567660574 0.1398063200361741 1.0 0.6063133725390817 7 P31930,P22695,Q10713,O43847 4 +Peptidase M16, N-terminal [IPR011765] 0.6669740023530372 1.4765126567660574 0.1398063200361741 1.0 0.6063133725390817 7 P31930,P22695,Q10713,O43847 4 +Glutamine amidotransferase type 2 domain [IPR017932] 0.7364532019704392 1.4574130180354086 0.1450024057450634 1.0 0.6099078271004099 4 Q9NWL6,Q06203,Q06210 3 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6564518827854758 1.4158222910085874 0.1568275413994799 1.0 0.6099078271004099 6 P13674,O15460,Q32P28 3 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6564518827854758 1.4158222910085874 0.1568275413994799 1.0 0.6099078271004099 6 P13674,O15460,Q32P28 3 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8999692212988619 1.4085181421847384 0.1589776987287698 1.0 0.6099078271004099 3 Q969X5,Q9Y282 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8999692212988619 1.4085181421847384 0.1589776987287698 1.0 0.6099078271004099 3 Q969X5,Q9Y282 2 +Chaperone DnaJ, C-terminal [IPR002939] 0.6895729326081634 1.4029383306588632 0.1606352294462696 1.0 0.6099078271004099 5 Q9UBS4,Q96EY1 2 +Rab-GTPase-TBC domain [IPR000195] 0.6976796128648528 1.2935525293083745 0.1958200285453906 1.0 0.6417154053631684 4 Q8TC07 1 +FAD dependent oxidoreductase [IPR006076] 0.6882102952663143 1.2535094494844954 0.2100203623086707 1.0 0.6606937327071526 4 Q96CU9,Q9H9P8 2 +Polyketide synthase, enoylreductase domain [IPR020843] 0.6171247489730055 1.252418844279588 0.2104172832632111 1.0 0.6606937327071526 7 Q99536,Q8N4Q0 2 +Sec23/Sec24 beta-sandwich [IPR012990] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.6698850517504192 5 O95486,Q15437 2 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.6698850517504192 5 O95486,Q15437 2 +Sec23/Sec24, trunk domain [IPR006896] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.6698850517504192 5 O95486,Q15437 2 +Sec23/Sec24, helical domain [IPR006900] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.6698850517504192 5 O95486,Q15437 2 +OCRE domain [IPR041591] 0.8525478220958667 1.227711121310235 0.2195554300832041 1.0 0.6708119137682669 3 P52756 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.6708119137682669 3 P01889,P10321 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.6708119137682669 3 P01889,P10321 2 +MHC class I-like antigen recognition-like [IPR011161] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.6708119137682669 3 P01889,P10321 2 +Immunoglobulin C1-set [IPR003597] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.6708119137682669 3 P01889,P10321 2 +Importin-beta, N-terminal domain [IPR001494] 0.5821645306438336 1.2254515458043196 0.220405135835811 1.0 0.6708119137682669 14 Q96P70,O95373,O15397 3 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.6731360330623134 5 P04350,Q9BUF5,Q13509 3 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.6731360330623134 5 P04350,Q9BUF5,Q13509 3 +Exportin-2, central domain [IPR013713] 0.843307679112467 1.192619288357776 0.2330185082779579 1.0 0.6882846580476321 3 O95373 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5892296360519 1.1378638646222805 0.2551773322045028 1.0 0.7150423640382858 8 P33527,Q9NUT2,P08183 3 +Fibronectin type III [IPR003961] 0.6585556493813451 1.1283352790327967 0.2591783496557767 1.0 0.7180220634430936 4 Q9Y6N7,Q15375 2 +Zinc finger, CHHC-type [IPR012996] 0.8233302554632207 1.117026849905495 0.263982845130033 1.0 0.7204531815007151 3 P31943,P52597 2 +B-box-type zinc finger [IPR000315] 0.5874392939932729 1.1092963129506752 0.2673023751529628 1.0 0.72273707213701 6 P19474,O15344,Q13049 3 +Cold shock domain [IPR011129] 0.6193980125351143 1.099348797335093 0.2716159553552593 1.0 0.723940796572512 5 P67809,Q9Y2V2 2 +Cold-shock protein, DNA-binding [IPR002059] 0.6193980125351143 1.099348797335093 0.2716159553552593 1.0 0.723940796572512 5 P67809,Q9Y2V2 2 +Zinc finger, RanBP2-type [IPR001876] 0.5727548021257776 1.0748896080138477 0.2824241551419426 1.0 0.7327827902278795 9 P52756,P35637,Q92804,Q01844 4 +Arf GTPase activating protein [IPR001164] 0.810710987996308 1.069527160505567 0.2848321970056067 1.0 0.7327827902278795 3 Q8N6T3,Q96P47 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5765013563207487 1.0689769049936069 0.2850800761811216 1.0 0.7327827902278795 7 P50570,O60313,Q9H4M9 3 +Dynamin, N-terminal [IPR045063] 0.5765013563207487 1.0689769049936069 0.2850800761811216 1.0 0.7327827902278795 7 P50570,O60313,Q9H4M9 3 +CBS domain [IPR000644] 0.5764496440418725 1.0687436425448789 0.2851852002976569 1.0 0.7327827902278795 7 P51790,Q6P4Q7,P51797 3 +K Homology domain, type 1 [IPR004088] 0.4915603427409396 1.0336193437774386 0.3013141526504572 1.0 0.744757622588866 22 Q9Y2W6,Q92945,Q9Y6M1,P51114,Q9NQT5,Q96AE4,Q96PU8,Q96I24,Q07666 9 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9587692307692312 1.0261828354275997 0.304805410514922 1.0 0.751260748399902 2 Q9BTY2 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7987072945521716 1.0245706569166582 0.3055658158090315 1.0 0.7520872048434766 3 O15460,Q32P28 2 +Butyrophylin-like, SPRY domain [IPR003879] 0.6331478665384793 1.0217257815018888 0.3069107052364677 1.0 0.7520942306193928 4 P19474 1 +SPRY-associated [IPR006574] 0.6331478665384793 1.0217257815018888 0.3069107052364677 1.0 0.7520942306193928 4 P19474 1 +Prenylcysteine lyase [IPR010795] 0.9507692307692276 0.9988870686378044 0.3178494011878168 1.0 0.7596055480029883 2 Q9UHG3 1 +Glycoside hydrolase 35, catalytic domain [IPR031330] 0.9492307692307648 0.993652058121697 0.3203922905292411 1.0 0.7625562278419036 2 Q8IW92 1 +DNA polymerase alpha/delta/epsilon, subunit B [IPR007185] 0.7896809107815335 0.9909346182386728 0.3217175070072717 1.0 0.7628053107321737 3 P56282 1 +Immunoglobulin-like domain [IPR007110] 0.5380157773276646 0.9775175011693812 0.3283130177643016 1.0 0.7707400903511084 13 P04439,P10321,Q9Y6N7,P01889,Q9Y624,Q9UDY8,Q08722 7 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.555788976183433 0.9757310960093968 0.3291977382147575 1.0 0.7707400903511084 7 O15173,O43169 2 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.6200738916256091 0.9672613061396912 0.3334134217457434 1.0 0.7751048491338489 4 O60749,Q13596,Q9Y5X3 3 +MD-2-related lipid-recognition domain [IPR003172] 0.9399999999999958 0.962344198237875 0.3358767341135196 1.0 0.77669641957407 2 P17900 1 +MIT domain [IPR007330] 0.7783933518005559 0.9491082405154144 0.3425655636923999 1.0 0.7844766033021586 3 Q6PHR2,Q8N0X7 2 +EGF-like calcium-binding domain [IPR001881] 0.7756232686980628 0.9388875846934616 0.347788464183173 1.0 0.7889227499220028 3 Q14517,Q04721 2 +Ubiquitin-associated domain [IPR015940] 0.5308320924952439 0.9225645705887108 0.3562341661326549 1.0 0.797385350608359 12 Q9BSL1,P54725,Q5T6F2,P54727 4 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.797385350608359 2 P05067 1 +BTB/POZ domain [IPR000210] 0.574632843469794 0.907310822937932 0.364242452440523 1.0 0.7987915031996233 5 Q96CX2,Q08380 2 +EF-hand domain [IPR002048] 0.3991521120440596 0.8957674104834293 0.3703769988611185 1.0 0.802412888761415 47 P80303,Q14257,O75071,Q9H4M9,P30626,Q66K14,Q14651,Q9NWM8,P0DP25,Q02818,Q9Y680,P31949,O43852 13 +ABC transporter-like, ATP-binding domain [IPR003439] 0.5251191283230592 0.8788341378261035 0.3794912136266088 1.0 0.8114142267135019 11 P33527,Q9NUT2,P08183 3 +Complex 1 LYR protein domain [IPR008011] 0.9144615384615384 0.8767519069470335 0.3806214063476694 1.0 0.8114142267135019 2 Q9NU23 1 +Extended PHD (ePHD) domain [IPR034732] 0.7534999080534829 0.857975341239675 0.3909060797520487 1.0 0.8180302946887921 3 Q7Z5J4 1 +Band 7 domain [IPR001107] 0.5240434468021608 0.8407013319619788 0.4005152742096665 1.0 0.8341415090853149 8 P27105 1 +Sterol-sensing domain [IPR000731] 0.9006153846153782 0.8310758825810145 0.4059307631517315 1.0 0.8392950344827562 2 O15118 1 +MRH domain [IPR044865] 0.5798016214139031 0.8021786039007127 0.4224496512054081 1.0 0.8513985278139764 4 P11717,P20645 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.8913846153846146 0.8009517222088222 0.4231595953441114 1.0 0.8521738199858354 2 Q96AE4 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.732411097415777 0.7822447793302257 0.4340707326597899 1.0 0.8619186121374299 3 Q99797 1 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.7291474299784573 0.7706670259654436 0.4409043215023978 1.0 0.865548275356422 3 O15344,Q13049 2 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5050742213348696 0.7630420131307988 0.4454383404363897 1.0 0.8662401190314514 9 O00170,Q9NWM8,Q96AY3,Q9Y680 4 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.5402486990788216 0.7628697446612691 0.445541081506382 1.0 0.8662401190314514 5 Q9UKU0 1 +Dynamin, GTPase domain [IPR001401] 0.7254539858417997 0.7576148435662268 0.4486815913958883 1.0 0.8686280753697521 3 P50570,O60313 2 +Gelsolin-like domain [IPR007123] 0.4997694587883269 0.7246705847228777 0.4686541450004733 1.0 0.8841209259414244 6 O95486,Q15437 2 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.867384615384605 0.7240150072326912 0.469056521778084 1.0 0.8841209259414244 2 P98179 1 +Fibronectin type II domain [IPR000562] 0.8621538461538423 0.7075395264029722 0.4792312584326796 1.0 0.8941432324105787 2 Q9UBV2 1 +CRK, C-terminal SH3 domain [IPR035458] 0.8553846153846041 0.686387894575549 0.4924685360562495 1.0 0.9065362931852716 2 P46108 1 +CRK, N-terminal SH3 domain [IPR035457] 0.8553846153846041 0.686387894575549 0.4924685360562495 1.0 0.9065362931852716 2 P46108 1 +K Homology domain [IPR004087] 0.4327426696605629 0.6780683875378769 0.497728333358344 1.0 0.9093781264985084 22 Q9Y2W6,Q92945,Q9Y6M1,P51114,Q96AE4,Q96PU8,Q96I24,Q07666 8 +XPC-binding domain [IPR015360] 0.8483076923076909 0.6644886981656425 0.5063775800801831 1.0 0.9149719033172964 2 P54725 1 +RAD23A/RAD23B, UBA1 domain [IPR041811] 0.8483076923076909 0.6644886981656425 0.5063775800801831 1.0 0.9149719033172964 2 P54725 1 +EH domain [IPR000261] 0.5147743669715323 0.6588082555345033 0.5100189053325841 1.0 0.9179913676731192 5 Q9H4M9 1 +Domain of unknown function DUF5600 [IPR040990] 0.8356923076922964 0.6260267831247082 0.5312973741143205 1.0 0.9255686185473035 2 Q9H4M9 1 +EH domain-containing protein, N-terminal [IPR031692] 0.8356923076922964 0.6260267831247082 0.5312973741143205 1.0 0.9255686185473035 2 Q9H4M9 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.9355321735398584 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.9355321735398584 3 Q9UL46 1 +COMM domain [IPR017920] 0.5267891745056162 0.5950711819470813 0.5517958909038008 1.0 0.9424414825084472 4 Q9H0A8,Q9Y6G5 2 +Rpn11/EIF3F, C-terminal [IPR024969] 0.5229700102794164 0.5807909137239853 0.561381379678187 1.0 0.9470825594055698 4 O00303,Q7L5N1 2 +SH2 domain [IPR000980] 0.4591117575023936 0.5727286084591061 0.5668284638848915 1.0 0.950762212150074 11 P42224,P46108,P46109 3 +FAD linked oxidase, N-terminal [IPR006094] 0.8123076923076753 0.556874051867798 0.5776134844284848 1.0 0.9573889849930608 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8123076923076753 0.556874051867798 0.5776134844284848 1.0 0.9573889849930608 2 Q15392 1 +CAP Gly-rich domain [IPR000938] 0.6633018613356467 0.5478146956190146 0.5838191469222536 1.0 0.9573889849930608 3 Q99426 1 +UAS [IPR006577] 0.6597089105536331 0.5363691778412908 0.5917034288805025 1.0 0.9573889849930608 3 O94888 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7984615384615237 0.517380008634426 0.6048909122481745 1.0 0.9595463897918668 2 O15460 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.4391095703286818 0.5132624278880306 0.6077677622406146 1.0 0.9598768809340724 14 Q01085,O95628,Q9UHX1,P11940,Q14011,Q13310 6 +Importin-alpha, importin-beta-binding domain [IPR002652] 0.6451215758695013 0.4908265410548116 0.6235491364254138 1.0 0.964683160081618 3 P52292,P52294 2 +Peptidase C14, p20 domain [IPR001309] 0.7824615384615206 0.4732284553958537 0.6360501985913916 1.0 0.9652985567814768 2 Q9UDY8 1 +Immunoglobulin V-set domain [IPR013106] 0.4912542469074424 0.4666097208341512 0.6407791308944326 1.0 0.9652985567814768 4 Q9Y6N7,Q9Y624 2 +Autophagy-related, C-terminal [IPR015412] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +VPS13, repeated coiled region [IPR031642] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.9652985567814768 2 Q709C8 1 +Elp3/MiaB/NifB [IPR006638] 0.7766153846153829 0.4575191037994307 0.6472979742786191 1.0 0.9652985567814768 2 Q9H9T3 1 +Radical SAM [IPR007197] 0.7766153846153829 0.4575191037994307 0.6472979742786191 1.0 0.9652985567814768 2 Q9H9T3 1 +Laminin G domain [IPR001791] 0.7753846153845952 0.4542418382411659 0.6496547729296474 1.0 0.965454058466067 2 Q14517 1 +EB1, C-terminal [IPR004953] 0.7729230769230782 0.4477190574339796 0.6543559660981992 1.0 0.9673273011419826 2 Q15555 1 +Sec7 domain [IPR000904] 0.7720000000000021 0.4452840085316692 0.6561145229101968 1.0 0.9673273011419826 2 Q92538 1 +Ribosomal protein S10 domain [IPR027486] 0.7655384615384642 0.4284091589161856 0.668353257674543 1.0 0.9681358046135772 2 Q96GC5 1 +MCM, AAA-lid domain [IPR041562] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.9681358046135772 6 P33993 1 +MCM OB domain [IPR033762] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.9681358046135772 6 P33993 1 +MCM N-terminal domain [IPR027925] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.9681358046135772 6 P33993 1 +MCM domain [IPR001208] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.9681358046135772 6 P33993 1 +Cyclin-like [IPR013763] 0.4771529596755297 0.4187525907826865 0.6753969562619393 1.0 0.9681358046135772 4 P06400 1 +U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.6203435578207339 0.4172030099138357 0.6765299238009552 1.0 0.9681358046135772 3 Q92688 1 +Chromo shadow domain [IPR008251] 0.6140350877193017 0.3992800680333351 0.6896868519836761 1.0 0.9714463750974766 3 P83916,P45973 2 +Chromo domain subgroup [IPR017984] 0.6140350877193017 0.3992800680333351 0.6896868519836761 1.0 0.9714463750974766 3 P83916,P45973 2 +SH3 domain [IPR001452] 0.3098914442980879 0.3956910414892498 0.692332965115082 1.0 0.9714463750974766 32 Q14847,P46108,Q9UQB8,P46109,Q9NZW5 5 +Major facilitator superfamily domain [IPR020846] 0.469634252428008 0.3940741203675234 0.6935263172030854 1.0 0.9714463750974766 4 Q9H2V7 1 +CP2 transcription factor [IPR007604] 0.7495384615384589 0.3879535328939645 0.6980504210068765 1.0 0.972736295305019 2 Q12800 1 +SAM domain [IPR041418] 0.7495384615384589 0.3879535328939645 0.6980504210068765 1.0 0.972736295305019 2 Q12800 1 +Fxr1, tudor domain [IPR041560] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.972736295305019 2 P51114 1 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.972736295305019 2 P51114 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.972736295305019 2 P51114 1 +Agenet-like domain [IPR008395] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.972736295305019 2 P51114 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.972736295305019 2 P51114 1 +Phosphoribosyltransferase domain [IPR000836] 0.4388666461349117 0.3746982083049222 0.7078849249102923 1.0 0.9751096231677002 5 P07741,Q06203,P00492,O60256 4 +B-box, C-terminal [IPR003649] 0.6009448405659243 0.363240539595364 0.7164252065381447 1.0 0.9784401619949028 3 O15344 1 +BAG domain [IPR003103] 0.4594622946864724 0.3616863881223605 0.7175864000884191 1.0 0.9784401619949028 4 O95817,O95429 2 +Asparagine synthase [IPR001962] 0.7360000000000021 0.3552774766245478 0.7223817273247293 1.0 0.9784401619949028 2 Q9NWL6 1 +GTPase effector domain [IPR020850] 0.7252307692307735 0.3303564980572543 0.7411306075543065 1.0 0.9789858027863052 2 P50570 1 +Dynamin stalk domain [IPR000375] 0.7252307692307735 0.3303564980572543 0.7411306075543065 1.0 0.9789858027863052 2 P50570 1 +Dynamin GTPase effector [IPR003130] 0.7252307692307735 0.3303564980572543 0.7411306075543065 1.0 0.9789858027863052 2 P50570 1 +Ataxin-2, C-terminal [IPR009818] 0.4488916256157529 0.3293229783307893 0.7419115777186407 1.0 0.9789858027863052 4 Q9BPZ3,Q9H074,Q8WWM7 3 +PABP, RNA recognition motif 2 [IPR045305] 0.7187692307692299 0.3158756732439867 0.7520968772172096 1.0 0.9789858027863052 2 P11940 1 +Staufen, C-terminal [IPR032478] 0.7175384615384613 0.3131583111911327 0.7541603894061739 1.0 0.9789858027863052 2 O95793 1 +AMP-dependent synthetase/ligase [IPR000873] 0.3932797351473825 0.3039504137508357 0.7611656689612065 1.0 0.9790119262317112 7 Q9UKU0 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7104615384615361 0.2977910410764044 0.7658626527056063 1.0 0.9790119262317112 2 O60506 1 +Glycosyl transferase CAP10 domain [IPR006598] 0.7052307692307673 0.2867181171129419 0.7743281643096429 1.0 0.9790119262317112 2 Q7Z4H8 1 +Sorting nexin, N-terminal [IPR005329] 0.6999999999999987 0.2758914669548462 0.7826314280450057 1.0 0.9790119262317112 2 Q13596 1 +Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886] 0.6929230769230768 0.2616409154325425 0.793598296548782 1.0 0.9790119262317112 2 Q13423 1 +Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698] 0.6929230769230768 0.2616409154325425 0.793598296548782 1.0 0.9790119262317112 2 Q13423 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4152658367644439 0.2360783280961267 0.8133718903580061 1.0 0.9790119262317112 4 P08238 1 +CARG-binding factor, N-terminal [IPR012956] 0.679076923076924 0.2351037264624208 0.8141282264553551 1.0 0.9790119262317112 2 Q14103 1 +Putative WW-binding domain and destruction box [IPR033461] 0.6769230769230764 0.2311377184708126 0.8172078132706002 1.0 0.9790119262317112 2 Q8TF05 1 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 0.9790119262317112 2 Q15118 1 +Histidine kinase domain [IPR005467] 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 0.9790119262317112 2 Q15118 1 +SKP1 component, POZ domain [IPR016073] 0.6695384615384636 0.2178746411391079 0.827526785954861 1.0 0.9790119262317112 2 P63208 1 +MoaB/Mog domain [IPR001453] 0.6572307692307691 0.1969293094891055 0.8438828571157355 1.0 0.9790119262317112 2 Q8NFF5 1 +Ubiquitin-like domain [IPR000626] 0.3566008819015844 0.1968593051157437 0.8439376402665468 1.0 0.9790119262317112 18 Q99426,Q9NRR5,P54725,P54727,P46379,Q5TDH0,O14562 7 +Immunoglobulin subtype [IPR003599] 0.3621823925843022 0.1948462165703604 0.8455133400262433 1.0 0.9790119262317112 9 Q9Y6N7,Q9UDY8,Q9Y624 3 +Immunoglobulin subtype 2 [IPR003598] 0.3621823925843022 0.1948462165703604 0.8455133400262433 1.0 0.9790119262317112 9 Q9Y6N7,Q9UDY8,Q9Y624 3 +STAT transcription factor, DNA-binding [IPR013801] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 0.9790119262317112 2 P42224 1 +STAT transcription factor, protein interaction [IPR013799] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 0.9790119262317112 2 P42224 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 0.9790119262317112 2 P42224 1 +NAD(P)-binding domain [IPR016040] 0.6489230769230776 0.1836157109335015 0.8543149371365715 1.0 0.9790119262317112 2 Q9BUP3 1 +CTP synthase, N-terminal [IPR017456] 0.648615384615379 0.1831354049899574 0.8546917763563253 1.0 0.9790119262317112 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.648615384615379 0.1831354049899574 0.8546917763563253 1.0 0.9790119262317112 2 P17812 1 +FAD/NAD(P)-binding domain [IPR023753] 0.3731637819580194 0.1804115713501521 0.8568294707504867 1.0 0.9790119262317112 5 Q16881 1 +THIF-type NAD/FAD binding fold [IPR000594] 0.3557336621455026 0.179552572664831 0.8575038409624269 1.0 0.9790119262317112 8 Q9GZZ9,Q13564,Q8TBC4,A0AVT1,O95396,P22314,Q9UBE0 7 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.3727557908405796 0.1794047958829499 0.8576198659121881 1.0 0.9790119262317112 5 Q9NZW5 1 +Guanylate kinase-like domain [IPR008144] 0.3727557908405796 0.1794047958829499 0.8576198659121881 1.0 0.9790119262317112 5 Q9NZW5 1 +Exportin-1/Importin-beta-like [IPR013598] 0.3897783251231427 0.1762772411745146 0.8600761409611999 1.0 0.9790119262317112 4 Q9Y5L0,Q9HAV4,O14980 3 +Tudor domain [IPR002999] 0.3525260196645626 0.1702491492016291 0.8648142003943342 1.0 0.9790119262317112 8 Q9Y2W6 1 +Ras GTPase-activating domain [IPR001936] 0.3609275548254383 0.1514028917212866 0.8796579084957703 1.0 0.9790119262317112 5 Q86VI3 1 +ERM family, FERM domain C-lobe [IPR041789] 0.4872268390273976 0.1273670667413462 0.8986498808495891 1.0 0.9872253719463646 3 P26038,P35241 2 +SLC12A transporter, C-terminal [IPR018491] 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 0.9914151642032364 2 Q9BXP2 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 0.9914151642032364 2 Q9BXP2 1 +PDZ domain [IPR001478] 0.3312860212350268 0.1170309669313455 0.9068355140266452 1.0 0.9914151642032364 20 Q6ZWJ1,O00560,P57105 3 +FCP1 homology domain [IPR004274] 0.3577648518741032 0.1155126040507394 0.9080388307625824 1.0 0.9914151642032364 4 Q9Y5B0,Q05D32 2 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3292105791736226 0.114709006422703 0.908675774962397 1.0 0.9914584999022866 7 O00303,O15372 2 +Rho GTPase-activating protein domain [IPR000198] 0.323345570111975 0.1082958446852273 0.9137610186928822 1.0 0.9946214661301832 6 Q9H0H5 1 +Nuclear transport factor 2 domain [IPR002075] 0.4646023054604475 0.0983861979313071 0.9216256339605188 1.0 0.9991071009789716 3 Q9UN86 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.4646023054604475 0.0983861979313071 0.9216256339605188 1.0 0.9991071009789716 3 Q9UN86 1 +Patatin-like phospholipase domain [IPR002641] 0.5775384615384648 0.0961535016094935 0.9233986599718432 1.0 0.9996232258628446 2 Q96AD5 1 +BAT2, N-terminal [IPR009738] 0.4539858417974811 0.0867778780328554 0.9308480720506704 1.0 1.0 3 Q9Y520,P48634 2 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.4465989535241663 0.0794191829286176 0.9366992110626224 1.0 1.0 3 O60568,O00469 2 +SCP2 sterol-binding domain [IPR003033] 0.4376731301939108 0.0712851997969484 0.9431707741126832 1.0 1.0 3 P51659,Q6YN16 2 +eRF1 domain 1/Pelota-like [IPR005140] 0.5446153846153947 0.0708175961379739 0.9435429272921548 1.0 1.0 2 P62495 1 +eRF1 domain 3 [IPR005142] 0.5446153846153947 0.0708175961379739 0.9435429272921548 1.0 1.0 2 P62495 1 +eRF1 domain 2 [IPR005141] 0.5446153846153947 0.0708175961379739 0.9435429272921548 1.0 1.0 2 P62495 1 +Dual specificity phosphatase, catalytic domain [IPR000340] 0.4358264081255821 0.0697029275852505 0.9444301115757034 1.0 1.0 3 Q8WUK0,Q99956 2 +Dual specificity protein phosphatase domain [IPR020422] 0.4358264081255821 0.0697029275852505 0.9444301115757034 1.0 1.0 3 Q8WUK0,Q99956 2 +SWIRM domain [IPR007526] 0.3217364532019622 0.0662330898864075 0.9471922526846952 1.0 1.0 4 Q8NB78,Q8TAQ2,O60341 3 +BAR domain [IPR004148] 0.4256694367497741 0.0615948074531886 0.9508855121447212 1.0 1.0 3 Q99961,Q9Y371 2 +Zinc finger, C3HC4 RING-type [IPR018957] 0.4207448445675636 0.0580140014411645 0.9537374757738436 1.0 1.0 3 Q5VTR2,O75150 2 +ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.519384615384618 0.0567530733543341 0.9547418956857848 1.0 1.0 2 P60842 1 +ENTH domain [IPR013809] 0.31219211822659 0.0563655132799728 0.955050629675577 1.0 1.0 4 O00291,Q9Y6I3,Q14677 3 +PIN domain [IPR002716] 0.4139735303170258 0.0534471993131771 0.9573755993146056 1.0 1.0 3 Q9UPR3,Q9ULX3 2 +Aminopeptidase P, N-terminal [IPR007865] 0.5110769230769354 0.0530040541463401 0.9577286775146496 1.0 1.0 2 Q9NQH7 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.5086153846153935 0.0519698111248363 0.9585527481277774 1.0 1.0 2 P29692 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.5086153846153935 0.0519698111248363 0.9585527481277774 1.0 1.0 2 P29692 1 +Stromalin conservative domain [IPR020839] 0.5018461538461669 0.0492975991146512 0.9606821328223412 1.0 1.0 2 Q8N3U4 1 +STAG [IPR013721] 0.5018461538461669 0.0492975991146512 0.9606821328223412 1.0 1.0 2 Q8N3U4 1 +ZU5 domain [IPR000906] 0.4966153846153869 0.0473983586256879 0.9621957371787416 1.0 1.0 2 Q07157 1 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.4855384615384642 0.0438207359949662 0.9650472980256376 1.0 1.0 2 P43246 1 +IKBKB, scaffold dimerization domain [IPR041185] 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +I-kappa-kinase-beta NEMO binding domain [IPR022007] 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.476307692307704 0.0412636526899216 0.967085709328288 1.0 1.0 2 Q14558 1 +Syntaxin, N-terminal domain [IPR006011] 0.3887349953832 0.0397542020864056 0.9682890887840944 1.0 1.0 3 O15400,Q86Y82 2 +Citron homology (CNH) domain [IPR001180] 0.3807325330871093 0.0363928673120451 0.9709691014741482 1.0 1.0 3 Q8WUH2,O14578 2 +PPM-type phosphatase domain [IPR001932] 0.3785780240073917 0.0355599363811939 0.9716332542388416 1.0 1.0 3 Q9H0C8,Q15750 2 +SARAH domain [IPR011524] 0.4480000000000068 0.0354445915936179 0.9717252280832878 1.0 1.0 2 Q13043 1 +Mst1 SARAH domain [IPR024205] 0.4480000000000068 0.0354445915936179 0.9717252280832878 1.0 1.0 2 Q13043 1 +RNA polymerase Rpb2, domain 4 [IPR007646] 0.4396923076923078 0.0342185690804436 0.97270285922653 1.0 1.0 2 Q9NW08 1 +RNA polymerase Rpb2, domain 5 [IPR007647] 0.4396923076923078 0.0342185690804436 0.97270285922653 1.0 1.0 2 Q9NW08 1 +Rad60/SUMO-like domain [IPR022617] 0.4344615384615378 0.0335395351763445 0.9732443390426826 1.0 1.0 2 Q8NCF5 1 +THUMP domain [IPR004114] 0.433846153846155 0.0334640610098098 0.9733045249299754 1.0 1.0 2 Q9NXG2 1 +ROCK, Rho binding domain [IPR015008] 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +PSP, proline-rich [IPR006568] 0.4107692307692309 0.0312157105806069 0.9750975107885992 1.0 1.0 2 Q6NZY4 1 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.4061538461538489 0.030883287438112 0.975362618258361 1.0 1.0 2 Q9NVE7 1 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.3604249542967412 0.029639557046302 0.9763545172003428 1.0 1.0 3 Q92538 1 +Methyltransferase type 11 [IPR013216] 0.3591874422899409 0.0293017225429614 0.9766239531029272 1.0 1.0 3 Q6FI81,Q6UX53 2 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.3707692307692229 0.029240208782543 0.9766730129611478 1.0 1.0 2 Q8NF37 1 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.3609230769230702 0.0289899456759871 0.9768726094138248 1.0 1.0 2 Q9HC38 1 +GCF, C-terminal [IPR022783] 0.3359999999999994 0.0285964039040736 0.9771864801818752 1.0 1.0 2 Q9UBB9 1 +AP180 N-terminal homology (ANTH) domain [IPR011417] 0.3119999999999914 0.0284200608418246 0.9773271244247064 1.0 1.0 2 O00291 1 +Class II aldolase/adducin N-terminal [IPR001303] 0.3431825176977588 0.0255844183693989 0.979588814342884 1.0 1.0 3 P35611,Q9UEY8 2 +HDGF-related, PWWP domain [IPR035496] 0.256366058066839 0.0205754292711047 0.9835843409177318 1.0 1.0 4 Q7Z4V5 1 +Glutaredoxin [IPR002109] 0.2988611880578689 0.0200259876421647 0.984022641579744 1.0 1.0 3 Q16881,Q86SX6 2 +Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.2865497076023441 0.019297378119199 0.98460387549804 1.0 1.0 3 Q16881,P00390 2 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.2515394088669841 0.0188964498491755 0.9849237116463596 1.0 1.0 4 Q16181,Q9UHD8,Q15019 3 +Zinc finger, UBP-type [IPR001607] 0.2588488765774145 0.0183690379576859 0.9853444524043397 1.0 1.0 3 Q53GS9,Q7Z569 2 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.2827808482108542 0.0082177347388414 0.9934432701244552 1.0 1.0 9 P61088,P49427 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..12c4e73e8034f77677f1309b4b790ce5fe5c64df --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin repeat and SOCS box protein 6, SOCS box domain [IPR037327]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CUT domain [IPR003350]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Caudal-like activation domain [IPR006820]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron Rho-interacting kinase, catalytic domain [IPR037708]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class IX myosin, motor domain [IPR036023]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4171 [IPR025228]", "Domain of unknown function DUF4195 [IPR025243]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferritin-like diiron domain [IPR009040]", "Ferritin/DPS protein domain [IPR008331]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GGA3, GAT domain [IPR044111]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucose-methanol-choline oxidoreductase, C-terminal [IPR007867]", "Glucose-methanol-choline oxidoreductase, N-terminal [IPR000172]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "ITPR-interacting domain [IPR029325]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon-related developmental regulator, C-terminal [IPR006921]", "Interferon-related developmental regulator, N-terminal [IPR007701]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MALT1 immunoglobulin-like domain [IPR041077]", "MALT1, death domain [IPR037940]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "Mitogen-activated protein kinase kinase kinase, N-terminal [IPR045801]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myotubularin-related 12-like C-terminal domain [IPR022587]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Npc2 like, ML domain [IPR033916]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear coactivator [IPR022174]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PICK1, BAR domain [IPR037959]", "PIGA, GPI anchor biosynthesis [IPR013234]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain-containing protein 2 [IPR033903]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome biogenesis factor 1, N-terminal, alpha/beta [IPR015343]", "Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold [IPR015342]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor 38, C-terminal [IPR024767]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "Quinolinate phosphoribosyl transferase, C-terminal [IPR002638]", "Quinolinate phosphoribosyl transferase, N-terminal [IPR022412]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RFX1 transcription activation region [IPR007668]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD3, SET domain [IPR044428]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD4, SET domain [IPR044421]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SOCS box domain [IPR001496]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Sperm-specific antigen 2, C-terminal [IPR029326]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Star-PAP, RNA recognition motif [IPR034388]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TROVE domain [IPR008858]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL8A", "ARMC10", "ARMC9", "ARMCX3", "ARMT1", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCKDHA", "BCS1L", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C1orf35", "C2CD2", "C2CD5", "C3orf58", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNB1", "CCNC", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2AIP", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPV", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLU", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNPY2", "COA3", "COG2", "COG4", "COIL", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUX1", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCK", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM208A", "FAM49B", "FAM8A1", "FANCA", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFRD1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRGQ", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPRIP", "ITSN2", "IVD", "IWS1", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LRSAM1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYRM2", "LZIC", "M6PR", "MACF1", "MAGED2", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "METAP1", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFN2", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCSTN", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAI1", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIPK1", "RMND1", "RNASEH2A", "RNF20", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RTCA", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCCPDH", "SCML2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A2", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMU1", "SMYD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSFA2", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK3", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URB2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WASF2", "WASHC4", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRN", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF131", "ZNF280C", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ACSL6", "ADD1", "ADD3", "AGAP3", "AIP", "ANP32B", "APP", "APRT", "ARFGAP1", "ASNSD1", "ATXN2L", "BAG3", "BAG4", "BAG6", "BAIAP2", "BRAP", "CALM3", "CALU", "CARHSP1", "CBX1", "CBX5", "CD47", "CDC34", "CIAPIN1", "CIRBP", "CIT", "CLCN3", "CLCN6", "CLINT1", "CNNM4", "CNOT4", "COMMD10", "COMMD4", "COPS6", "CRK", "CRKL", "CTDP1", "CTDSPL2", "CTPS1", "CYB5B", "DCUN1D3", "DCUN1D4", "DDI2", "DHCR24", "DNAJA3", "DNAJB11", "DNM2", "DUSP9", "EEF1D", "EFCAB14", "EHD1", "EIF3F", "EIF3H", "EIF4A1", "ELP3", "EPHA7", "EPN1", "ERAP1", "ERGIC1", "ERGIC3", "ETF1", "EWSR1", "EXOSC3", "F11R", "FAT1", "FKBP10", "FKBP14", "FKBP7", "FLAD1", "FOXRED1", "FUBP1", "FUBP3", "FUCA2", "FUS", "FXR1", "G3BP2", "GBF1", "GFPT1", "GLB1L2", "GLOD4", "GLRX5", "GM2A", "GSR", "HDGFL2", "HIP1", "HLA-A", "HLA-B", "HLA-C", "HNRNPD", "HNRNPF", "HNRNPH1", "HPRT1", "HSD17B4", "HSDL2", "HSP90AB1", "HTATIP2", "IDH2", "IGF2BP2", "IGF2R", "IKBKB", "ILKAP", "IPO7", "IPO8", "IPO9", "IQGAP3", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KHDRBS1", "KHSRP", "KPNA1", "KPNA2", "L2HGDH", "LASP1", "LGALS3BP", "LNPEP", "LPCAT1", "LTA4H", "LYRM2", "M6PR", "MALT1", "MAPRE2", "MCM7", "METTL7B", "MID1", "MIPEP", "MOCS3", "MPP6", "MRPL48", "MSH2", "MSN", "NAE1", "NFATC2IP", "NNT", "NOB1", "NOTCH2", "NPC1", "NPEPPS", "NRDC", "NUCB1", "NUCB2", "OPA1", "P3H1", "P4HA1", "P4HA2", "PABPC1", "PABPC4", "PAIP1", "PAIP2", "PANK4", "PAOX", "PCYOX1", "PDK1", "PGRMC2", "PLOD2", "PLOD3", "PLS1", "PMPCA", "PNPLA2", "POLE2", "POLR2B", "POLR3B", "PPAT", "PPP4R1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSME2", "PTPMT1", "PUF60", "QKI", "RACGAP1", "RAD23A", "RAD23B", "RAI1", "RB1", "RBM3", "RBM5", "RCN2", "RDX", "RNF20", "RNF40", "ROBO1", "ROCK2", "S100A11", "SAE1", "SDCBP", "SEC23B", "SEC24A", "SEL1L", "SEPT2", "SEPT7", "SEPT9", "SH3GL1", "SH3GLB1", "SKP1", "SLC12A9", "SMARCC2", "SMG5", "SNX1", "SNX2", "SNX5", "SPART", "SPNS1", "SRI", "STAG2", "STAT1", "STAU1", "STK4", "STOM", "STX10", "STX12", "STX5", "STX7", "STXBP4", "SYNCRIP", "SYNJ2BP", "TAB1", "TAF15", "TBC1D15", "TBC1D9B", "TBCB", "TDRKH", "TFCP2", "TFIP11", "TGFBRAP1", "THUMPD1", "TIAL1", "TJP1", "TLCD1", "TNPO3", "TRAM1", "TRIM21", "TRIM32", "TUBB3", "TUBB4A", "TUBB6", "TXNRD1", "UBA1", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBE2N", "UBFD1", "UBQLN4", "UBXN7", "ULK3", "UQCRC1", "UQCRC2", "USP39", "VAT1", "VPS13C", "XPNPEP3", "XPO1", "XPO5", "YBX1", "ZADH2", "ZCCHC8"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..aa84e306eb62ca38e36af8079299ba9e8191db4b --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "ThiF/MoeB/HesA family [IPR045886]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a83c51b54e7c112de1a139c4197aec6f45235acf --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2b0658bcf6b983fd7b3123b6ea7d3c597d93f9395b24aa98b458fc400259c93 +size 139043 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bc755871422262cbf96416d3ab29ccb4f251bd04 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b7273db34574138ae02d0513af448359409337b530822f1e68c6bf2cdcddb31 +size 122221 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e247f938e3c03b50dc77ea1949c4edb313818806 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1d0c26189cb42f86256bcb5819ada79b929425d8e50c2cfd0b3900b352384d0 +size 229561 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..79349ba8372f7a80b10ce5b1426c1aa307cedfbb --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 4 6 2.4720646689753 0.0134335213238978 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0003329397892747 0.0378187125466048 0.0025156479029566 2.2502069418558096e-05 1.3632546196600551e-05 +Proteasome B-type subunit [IPR023333] 4 7 2.016316727483837 0.0437668668574251 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0004925675778475 0.0424464003246627 0.0032139762811053 0.0010839430889874 2.9438380117440665e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..95648201aec0b2eb68a44edf8c7966d5a1173c55 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 2510, + "title": "Average number of proteins per term", + "value": 1.2872509960159362 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..691295af2aaf4f9b91fe1144c687337bb9ffeb2e --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bf1264d64b552d66d408dedcf57ec86a15fd97d8 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,123 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.9069167935981328 2.4720646689752996 0.0134335213238978 0.9999999999999982 0.3280749223531436 6 P09960,Q9UIQ6,P55786,Q9NZ08 4 +Aminopeptidase N-type [IPR034016] 0.9104064039408852 2.1752062960115257 0.0296146605921621 1.0 0.3280749223531436 4 Q9UIQ6,P55786,Q9NZ08 3 +Eukaryotic porin/Tom40 [IPR027246] 0.8813518104606566 2.0581749925596364 0.0395733382523593 1.0 0.3280749223531436 4 P45880,P21796 2 +Proteasome B-type subunit [IPR023333] 0.7903831227232498 2.016316727483837 0.0437668668574251 1.0 0.3280749223531436 7 P49721,P20618,P28070,P28072 4 +Proteasome, subunit alpha/beta [IPR001353] 0.7181382573463668 1.9061672486284145 0.056628509982967 1.0 0.3283607290986203 14 P28070,P28072,P60900,P49721,P20618 5 +Defective-in-cullin neddylation protein [IPR014764] 0.8102431405434726 1.766490796742742 0.0773135442394765 1.0 0.361025460446886 4 Q8IWE4,Q92564 2 +Syntaxin [IPR045242] 0.7229161796360261 1.7067758034989642 0.0878637314370422 1.0 0.3750765823901414 6 O60499,Q13190 2 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9775315481686676 1.7041173067226685 0.0883591739622728 1.0 0.3757462440479864 3 P10619,Q9HB40 2 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.9183968322007608 1.478890633661463 0.1391695470506997 1.0 0.4479676752055872 3 Q9NPH0 1 +Glutathione Transferase family [IPR040079] 0.6475780429223698 1.467385066316255 0.1422713346000421 1.0 0.4497494330555489 11 O15217 1 +Porin, eukaryotic type [IPR001925] 0.9076638965835648 1.4379046491687717 0.1504611103996798 1.0 0.45943721058783 3 P45880,P21796 2 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8999692212988619 1.4085181421847384 0.1589776987287698 1.0 0.46926973274636 3 Q969X5,Q9Y282 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.887349953831949 1.3603343585239454 0.1737241403345961 1.0 0.487748984608318 3 Q01105,P55209 2 +TAF15/EWS/TLS family [IPR034870] 0.8851954447522321 1.352110555596436 0.176339951068039 1.0 0.4907610698320134 3 Q92804,Q01844 2 +Initiation factor 2B-related [IPR000649] 0.6813604850886481 1.2245561649885852 0.2207424924460319 1.0 0.548938462573783 4 Q9UI10 1 +Tubulin [IPR000217] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.5503014519854896 5 P04350,Q9BUF5,Q13509 3 +Beta tubulin [IPR002453] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.5503014519854896 5 P04350,Q9BUF5,Q13509 3 +ER lumen protein retaining receptor [IPR000133] 0.9959999999999998 1.154598292779908 0.2482549661260811 1.0 0.5818113585214413 2 P24390 1 +Palmitoyl protein thioesterase [IPR002472] 0.9901538461538456 1.134303877869811 0.2566671030948155 1.0 0.5920404237932185 2 P50897 1 +Tetraspanin/Peripherin [IPR018499] 0.9864615384615384 1.1215086267211023 0.2620714215346917 1.0 0.5963667898566523 2 O43657 1 +Tetraspanin, animals [IPR000301] 0.9864615384615384 1.1215086267211023 0.2620714215346917 1.0 0.5963667898566523 2 O43657 1 +Type 1 protein exporter [IPR039421] 0.6226060928329152 1.1132057761887244 0.265620062476005 1.0 0.6002297975421714 5 Q9NUT2,P08183 2 +Nucleobindin [IPR040250] 0.983692307692306 1.1119240882883334 0.2661707907075654 1.0 0.6002297975421714 2 P80303 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.980615384615384 1.1012870288426269 0.2707717547353598 1.0 0.6040594298208457 2 P48735 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9784615384615372 1.0938491192636686 0.2740211571899404 1.0 0.6054235004678474 2 Q5VW38 1 +CD36 family [IPR002159] 0.9756923076923067 1.084296117379949 0.278233526240998 1.0 0.612022221890536 2 Q8WTV0 1 +Haem oxygenase [IPR002051] 0.9741538461538436 1.078993888763519 0.2805904519777957 1.0 0.612867763371601 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9741538461538436 1.078993888763519 0.2805904519777957 1.0 0.612867763371601 2 P30519 1 +Glycoside hydrolase, family 29 [IPR000933] 0.9587692307692312 1.0261828354275997 0.304805410514922 1.0 0.6370204666048745 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9587692307692312 1.0261828354275997 0.304805410514922 1.0 0.6370204666048745 2 Q9BTY2 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.7950138504155143 1.0107884953005115 0.3121176706363413 1.0 0.6469160638292458 3 P28074,P28072 2 +Prenylcysteine oxidase [IPR017046] 0.9507692307692276 0.9988870686378044 0.3178494011878168 1.0 0.6525416365628269 2 Q9UHG3 1 +SCAMP [IPR007273] 0.7910635434319355 0.9960765855656344 0.3192129354190121 1.0 0.653391632571849 3 O15127 1 +Beta-galactosidase 1-like [IPR026283] 0.9492307692307648 0.993652058121697 0.3203922905292411 1.0 0.653391632571849 2 Q8IW92 1 +Glycoside hydrolase, family 35 [IPR001944] 0.9492307692307648 0.993652058121697 0.3203922905292411 1.0 0.653391632571849 2 Q8IW92 1 +Molecular chaperone regulator BAG [IPR039773] 0.7842413050169301 0.9707433111048228 0.3316761183357091 1.0 0.6654062836723691 3 O95817,O95429 2 +Adaptor protein complex, sigma subunit [IPR016635] 0.7804871185968338 0.9568454411675392 0.3386452724874362 1.0 0.6719364695205257 3 P61966 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9372307692307628 0.952987538132225 0.3405963847916249 1.0 0.6736776405255938 2 Q9H2D1 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9329230769230772 0.9384672161042712 0.3480043571876248 1.0 0.6818820738024499 2 Q9Y487 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9329230769230772 0.9384672161042712 0.3480043571876248 1.0 0.6818820738024499 2 Q9Y487 1 +Amyloidogenic glycoprotein [IPR008155] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.6946745700542751 2 P05067 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.9236923076923036 0.9075009456658516 0.3641419496264624 1.0 0.6970634642840944 2 P13473 1 +Cytochrome P450 [IPR001128] 0.9141538461538408 0.8757308913271216 0.3811763476014924 1.0 0.7118695182140967 2 Q6UW02 1 +Major facilitator superfamily [IPR011701] 0.5894933139642126 0.8414479541185195 0.4000970303722262 1.0 0.7325990561986505 4 Q9H2V7 1 +Prefoldin alpha-like [IPR004127] 0.7371498922745481 0.7991269151985877 0.4242168243874407 1.0 0.7481232418399097 3 P61758,Q9UBK9 2 +Peptidase M3A/M3B [IPR045090] 0.732411097415777 0.7822447793302257 0.4340707326597899 1.0 0.7547843234299274 3 Q99797 1 +Prefoldin beta-like [IPR002777] 0.5718660710566427 0.770292522855498 0.4411263907392089 1.0 0.7593698471611812 4 Q9UHV9 1 +Dynamin [IPR022812] 0.7254539858417997 0.7576148435662268 0.4486815913958883 1.0 0.7635191826465625 3 P50570,O60313 2 +Chloride channel, voltage gated [IPR001807] 0.7173992908854291 0.7293440734190008 0.4657912188625173 1.0 0.7752890977088318 3 P51797 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.8664615384615388 0.7210994845131146 0.4708483081863694 1.0 0.7795707477228149 2 Q96N66 1 +KH domain-containing BBP-like [IPR045071] 0.7011388119421385 0.6731513811888739 0.5008509884209169 1.0 0.8032817769562309 3 Q96PU8,Q07666 2 +UV excision repair protein Rad23 [IPR004806] 0.8483076923076909 0.6644886981656425 0.5063775800801831 1.0 0.8073728257237872 2 P54725 1 +Proteasome activator PA28 [IPR009077] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.8299132857235867 3 Q9UL46 1 +Haloacid dehalogenase-like hydrolase [IPR041492] 0.8224615384615364 0.5865403139597393 0.5575124786007621 1.0 0.8359092248244422 2 Q08623 1 +HAD hydrolase, subfamily IA [IPR006439] 0.8224615384615364 0.5865403139597393 0.5575124786007621 1.0 0.8359092248244422 2 Q08623 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.5200123152709271 0.5698034934046964 0.5688109858846961 1.0 0.8438035310700871 4 P04899,P63096,P08754 3 +Prolyl 4-hydroxylase [IPR045054] 0.7984615384615237 0.517380008634426 0.6048909122481745 1.0 0.8645364150448871 2 O15460 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.7960000000000008 0.5104807169897059 0.6097147205736004 1.0 0.8660916517485779 2 O43447 1 +Importin subunit alpha [IPR024931] 0.6451215758695013 0.4908265410548116 0.6235491364254138 1.0 0.8773028769214062 3 P52292,P52294 2 +Vacuolar protein sorting-associated protein 13 [IPR026847] 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 0.886804359956813 2 Q709C8 1 +Tropomyosin [IPR000533] 0.6343490304709174 0.4582098663600896 0.6468016721676393 1.0 0.8890866358930858 3 P06753,P67936 2 +Flotillin family [IPR027705] 0.7732307692307638 0.4485320774996426 0.6537692411408824 1.0 0.890145895155858 2 O75955 1 +Microtubule-associated protein RP/EB [IPR027328] 0.7729230769230782 0.4477190574339796 0.6543559660981992 1.0 0.890145895155858 2 Q15555 1 +Mitochondrial carrier protein [IPR002067] 0.4241471920786208 0.4449539148345905 0.656353058791181 1.0 0.890145895155858 14 Q86VD7,Q96H78 2 +Cleft lip and palate transmembrane 1 [IPR008429] 0.7673846153846048 0.4331998406076452 0.6648695946728769 1.0 0.892896031369139 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.7673846153846048 0.4331998406076452 0.6648695946728769 1.0 0.892896031369139 2 Q96KA5 1 +Mini-chromosome maintenance protein [IPR031327] 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 0.8965633635821914 6 P33993 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7470769230769216 0.3819037689645785 0.7025327445792513 1.0 0.910619407309052 2 P51114 1 +Sulfotransferase [IPR005331] 0.7433846153845942 0.3729188303076821 0.7092088567727566 1.0 0.914755514131356 2 Q8NCH0 1 +Profilin [IPR005455] 0.7418461538461578 0.3692071912179709 0.7119732961446585 1.0 0.9150296842412152 2 P07737 1 +Profilin1/2/3, vertebrate [IPR005454] 0.7418461538461578 0.3692071912179709 0.7119732961446585 1.0 0.9150296842412152 2 P07737 1 +Dynein light chain, type 1/2 [IPR001372] 0.7276923076923058 0.3359668969371918 0.7368958294050554 1.0 0.927933983974442 2 Q96FJ2 1 +Small GTPase Rho [IPR003578] 0.4262396057899655 0.3328336399563942 0.7392598635585088 1.0 0.927933983974442 5 P84095,P63000,Q8IXI1,P60953 4 +Graves disease carrier protein [IPR002167] 0.5877161618698306 0.328483233920038 0.742546319052191 1.0 0.927933983974442 3 Q86VD7 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.7187692307692299 0.3158756732439867 0.7520968772172096 1.0 0.9299547043341144 2 P11940 1 +Microtubule associated protein 1 [IPR026074] 0.5792551554324445 0.3071750632660859 0.7587101252004571 1.0 0.9299547043341144 3 P46821,Q66K74 2 +Annexin [IPR001464] 0.4099788468673957 0.2818686820521908 0.7780442043425002 1.0 0.93733555723671 5 P50995,P04083 2 +Torsin [IPR010448] 0.7003076923076776 0.2765214568807739 0.7821475816667947 1.0 0.93733555723671 2 O14657 1 +Torsin 1/2 [IPR017378] 0.7003076923076776 0.2765214568807739 0.7821475816667947 1.0 0.93733555723671 2 O14657 1 +Kinesin light chain [IPR002151] 0.6963076923076704 0.2683990323280565 0.7883921842871837 1.0 0.9393072923385818 2 Q9NSK0 1 +Ras GTPase-activating protein-binding protein [IPR039539] 0.695999999999999 0.2677803003669992 0.7888684351592552 1.0 0.9393072923385818 2 Q9UN86 1 +Tricarboxylate/iron carrier [IPR004686] 0.5494006463611478 0.2381159996201367 0.811791125689024 1.0 0.9434717286757948 3 Q96NB2 1 +Heat shock protein Hsp90 family [IPR001404] 0.4152658367644439 0.2360783280961267 0.8133718903580061 1.0 0.9434717286757948 4 P08238 1 +PDK/BCKDK protein kinase [IPR039028] 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 0.9434717286757948 2 Q15118 1 +S-phase kinase-associated protein 1-like [IPR001232] 0.6695384615384636 0.2178746411391079 0.827526785954861 1.0 0.9434717286757948 2 P63208 1 +Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554] 0.536164973838108 0.2107105532123854 0.8331131392160869 1.0 0.9434717286757948 3 Q14738,Q16537 2 +Taxilin family [IPR026183] 0.6569230769230792 0.1964243422707687 0.8442780449822276 1.0 0.9434717286757948 2 P40222 1 +G-protein alpha subunit, group I [IPR001408] 0.5281625115420171 0.1951334144869586 0.8452885043712797 1.0 0.9434717286757948 3 P04899,P63096 2 +Transcription factor STAT [IPR001217] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 0.9434717286757948 2 P42224 1 +CTP synthase [IPR004468] 0.648615384615379 0.1831354049899574 0.8546917763563253 1.0 0.9434717286757948 2 P17812 1 +ThiF/MoeB/HesA family [IPR045886] 0.3557336621455026 0.179552572664831 0.8575038409624269 1.0 0.9434717286757948 8 Q9GZZ9,Q13564,Q8TBC4,A0AVT1,O95396,P22314,Q9UBE0 7 +Aminoacyl-tRNA synthetase, class Ic [IPR002305] 0.3876231527093509 0.1716784617092892 0.8636903194571071 1.0 0.9434717286757948 4 Q9UGM6,P23381,Q9Y2Z4 3 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.5106186518928946 0.1636428967421492 0.8700122731617372 1.0 0.9434717286757948 3 A0AVT1,Q9UBE0 2 +Tropomodulin [IPR004934] 0.6258461538461582 0.1501227598239211 0.8806677637250662 1.0 0.9442443771678412 2 Q9NYL9 1 +Ezrin/radixin/moesin [IPR011174] 0.4872268390273976 0.1273670667413462 0.8986498808495891 1.0 0.953371975336207 3 P26038,P35241 2 +Ribosomal protein S2 [IPR001865] 0.6033846153846214 0.1223843981649246 0.9025945940848974 1.0 0.9543017822885816 2 Q9Y399 1 +Glutathione S-transferase, Mu class [IPR003081] 0.6009230769230831 0.119629328873148 0.9047767854794956 1.0 0.9553310461016272 2 P28161 1 +SLC12A transporter family [IPR004842] 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 0.9553310461016272 2 Q9BXP2 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.5803076923076875 0.0986847332621538 0.9213885907821356 1.0 0.961897025349812 2 P36405 1 +Protein PRRC2 [IPR033184] 0.4539858417974811 0.0867778780328554 0.9308480720506704 1.0 0.9662649548582228 3 Q9Y520,P48634 2 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.5532307692307787 0.076634812509987 0.938914063997926 1.0 0.973028200096942 2 O60884 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.4392120652508513 0.0726297887186271 0.9421007213439574 1.0 0.9759276973063694 3 P12235,P12236 2 +Cytoplasmic FMR1-interacting [IPR008081] 0.5181538461538554 0.0561718557721738 0.9552049015923156 1.0 0.985185893944866 2 Q7L576 1 +Ribosomal protein L12/P1/P2 family [IPR027534] 0.5144615384615443 0.0544825395876206 0.956550719316841 1.0 0.9856386014127774 2 P05386 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 0.9856386014127774 2 A0AVT1 1 +MT-A70-like [IPR007757] 0.5040000000000122 0.0501210411774491 0.9600259323743504 1.0 0.9856386014127774 2 Q86U44 1 +Cohesin subunit Scc3/SA [IPR039662] 0.5018461538461669 0.0492975991146512 0.9606821328223412 1.0 0.9856386014127774 2 Q8N3U4 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.5012307692307822 0.0490668272065001 0.9608660396048077 1.0 0.9856386014127774 2 P06737 1 +Glycosyl transferase, family 35 [IPR000811] 0.5012307692307822 0.0490668272065001 0.9608660396048077 1.0 0.9856386014127774 2 P06737 1 +Tryptophan-tRNA ligase [IPR002306] 0.4947692307692355 0.046761107749006 0.9627036266252016 1.0 0.9856386014127774 2 P23381 1 +Intracellular chloride channel [IPR002946] 0.4904615384615521 0.0453389434925643 0.963837146921194 1.0 0.9856386014127774 2 O00299 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.4895384615384643 0.0450457244244358 0.9640708631010746 1.0 0.9856386014127774 2 Q96AX1 1 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.476307692307704 0.0412636526899216 0.967085709328288 1.0 0.9875448048877146 2 Q14558 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.4689230769230801 0.0394700742205575 0.9685156122296492 1.0 0.9886027599416104 2 P07910 1 +Exportin-1/5 [IPR045065] 0.4526153846153863 0.0362107341645774 0.9711143269781994 1.0 0.990449801184592 2 Q9HAV4 1 +Protein phosphatase 2C family [IPR015655] 0.3785780240073917 0.0355599363811939 0.9716332542388416 1.0 0.9905765508283886 3 Q9H0C8,Q15750 2 +Rho-associated protein kinase 1/2 [IPR020684] 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 0.992339047658242 2 O75116 1 +Tyrosine-tRNA ligase [IPR002307] 0.3873846153846144 0.029840131265473 0.9761945528843692 1.0 0.99242891447731 2 Q9Y2Z4 1 +Macrophage migration inhibitory factor [IPR001398] 0.2735384615384519 0.0283235546274284 0.9774040942581316 1.0 0.99242891447731 2 P14174 1 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 0.9980454243974012 3 P30876,Q9NW08 2 +ADF/Cofilin [IPR017904] 0.2776238842720889 0.0189082183201101 0.9849143234424408 1.0 0.9980454243974012 3 P60981,Q9Y281 2 +Septin [IPR016491] 0.2515394088669841 0.0188964498491755 0.9849237116463596 1.0 0.9980454243974012 4 Q16181,Q9UHD8,Q15019 3 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..78a6c649d966554e45acf59b6e7237c21721f0a6 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-binding protein GGA3 [IPR027422]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "ATR-interacting protein [IPR033349]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 8/Plant actin-related protein 9 [IPR027668]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit [IPR006111]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Bombesin receptor-activated protein [IPR038757]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain-containing protein 8 [IPR038002]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 10 [IPR037361]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-6 [IPR002248]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Citron Rho-interacting kinase [IPR017405]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein R3HC1/R3HCL [IPR039884]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-7 [IPR031223]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin C/cyclin-like subunit Ssn8 [IPR028367]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta subunit 3 [IPR019038]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit RPB6 [IPR028363]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 4 [IPR030612]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase Rad18 [IPR039577]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERp19 [IPR037462]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferritin [IPR001519]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GPCR-associated sorting protein [IPR043374]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucose-methanol-choline oxidoreductase [IPR012132]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "Guided entry of tail-anchored proteins factor CAMLG [IPR016719]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HIRA-interacting protein 3 [IPR037647]", "HMG domain-containing protein 4 [IPR042477]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase EHMT2 [IPR038034]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Hyccin [IPR018619]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase [IPR033942]", "Inositol monophosphatase, lithium-sensitive [IPR020552]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-related developmental regulator [IPR039777]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(3)malignant brain tumour-like protein 2 [IPR038038]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthioribulose-1-phosphate dehydratase [IPR017714]", "Methylthioribulose-1-phosphate dehydratase, eukaryotes [IPR027514]", "Methylthiotransferase [IPR005839]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [IPR033540]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 12 [IPR030576]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "N-acetylgalactosamine-6-sulfatase [IPR035626]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nicotinate-nucleotide pyrophosphorylase [IPR004393]", "Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD [IPR027277]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear receptor coactivator 4 [IPR039947]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Pat1-like [IPR039900]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome biogenesis factor 1 [IPR025653]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol N-acetylglucosaminyltransferase subunit PIG-A/GPI3 [IPR039507]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotriesterase [IPR001559]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein TESPA1-like [IPR043444]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM8A1 [IPR039871]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein ITPRID2 [IPR026648]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein Nucling [IPR030227]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, RluC/RluD [IPR006225]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuosine salvage protein family [IPR019438]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RFX-like DNA-binding protein [IPR039779]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, subunit omega/Rpo6/RPB6 [IPR006110]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein Rsm22-like [IPR015324]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Roundabout homologue 1 [IPR032986]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase Bud32 [IPR022495]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short coiled-coil protein [IPR019357]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntaxin-16 [IPR028673]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit 13 [IPR010378]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IID, subunit 13 [IPR003195]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 161A/B [IPR019395]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0489 [IPR024131]", "Uncharacterised protein family UPF0729 [IPR026776]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-IXb [IPR028557]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat and coiled-coil-containing protein family [IPR028041]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 131 [IPR027758]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC6", "ARMC9", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf22", "C5orf51", "C6orf89", "C8orf33", "C9orf64", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP2", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC167", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPF", "CENPI", "CENPU", "CEP170", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHDH", "CHERP", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRNKL1", "CROT", "CRTAP", "CS", "CSGALNACT2", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWF19L1", "CXorf56", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAP3", "DARS", "DARS2", "DBN1", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM126A", "FAM136A", "FAM162A", "FAM177A1", "FAM207A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FN3KRP", "FNTB", "FOCAD", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALNS", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GCAT", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPS1", "GPT2", "GRIPAP1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAK16", "MALT1", "MAN1A2", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL14", "METTL17", "METTL3", "METTL9", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCOA4", "NCSTN", "NDC1", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM47", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RER1", "REXO4", "RFC1", "RFT1", "RFX1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPEP", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCOC", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMPD4", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPNS1", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSFA2", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKFC", "TLE3", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM161A", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53RK", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC13", "TRAPPC5", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TSR2", "TST", "TTC19", "TTC26", "TTC37", "TTC38", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBR2", "UBR4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRQ", "URB1", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDCP", "WDR12", "WDR18", "WDR33", "WDR46", "WDR82", "WDR91", "WFS1", "WIPI2", "WRN", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YIF1A", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7A", "ZCCHC3", "ZFYVE16", "ZMPSTE24", "ZNF131", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABCB8", "ACP6", "ANXA1", "ANXA11", "AP1S1", "APP", "ARL3", "ATP6V0A2", "BAG3", "BAG4", "CDC42", "CFL2", "CHST14", "CLCN6", "CLIC1", "CLPTM1L", "CTPS1", "CTSA", "CYFIP1", "CYP20A1", "DCUN1D3", "DCUN1D4", "DNAJA2", "DNM2", "DSTN", "DYNLL2", "EIF2B4", "ERAP1", "ERGIC1", "ERGIC3", "EWSR1", "FLOT1", "FUCA2", "FXR1", "G3BP2", "GLB1L2", "GNAI1", "GNAI2", "GNAI3", "GPR107", "GSTA4", "GSTM2", "HMOX2", "HNRNPC", "HSP90AB1", "IDH2", "ILKAP", "KDELR1", "KHDRBS1", "KLC4", "KPNA1", "KPNA2", "LAMP2", "LNPEP", "LTA4H", "MAP1B", "MAP1S", "MAPRE2", "MBOAT7", "MCM7", "METTL3", "MIF", "MIPEP", "MOCS3", "MRPS2", "MSN", "NAE1", "NAP1L1", "NPEPPS", "NUCB2", "OPA1", "P4HA2", "PABPC1", "PCYOX1", "PDK1", "PFDN2", "PFN1", "POLR2B", "POLR3B", "PPIH", "PPP2R5D", "PPP2R5E", "PPT1", "PRPSAP1", "PRRC2A", "PRRC2C", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSME2", "PUDP", "PYGL", "QKI", "RAC1", "RAD23A", "RDX", "RHOG", "RHOT2", "ROCK2", "RPLP1", "SAE1", "SCAMP2", "SCARB1", "SCPEP1", "SEPT2", "SEPT7", "SEPT9", "SET", "SFXN2", "SKP1", "SLC12A9", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A6", "SPNS1", "STAG2", "STAT1", "STX10", "STX5", "TAB1", "TAF15", "TMOD3", "TOR1B", "TPM3", "TPM4", "TSPAN6", "TUBB3", "TUBB4A", "TUBB6", "TXLNA", "UBA1", "UBA3", "UBA5", "UBA6", "UXT", "VBP1", "VDAC1", "VDAC2", "VPS13C", "VPS33A", "WARS", "WARS2", "XPO5", "YARS2"]} \ No newline at end of file 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b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycoside hydrolase superfamily [IPR017853] 9 16 2.7664835491334263 0.0056664443770335 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 1.634099121163838e-11 0.1178616319260966 0.0019631407021181 2.37480925355545e-10 1.8840304280318945e-07 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 4 6 2.4720646689753 0.0134335213238978 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0004925675778475 0.0424464003246627 0.0032139762811053 3.972711663948022e-05 2.9438380117440665e-05 +Peptidase M4/M1, CTD superfamily [IPR027268] 4 6 2.4720646689753 0.0134335213238978 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0004925675778475 0.0424464003246627 0.0032139762811053 3.972711663948022e-05 2.9438380117440665e-05 +Mitochondrial carrier domain superfamily [IPR023395] 7 24 2.3406506941693817 0.0192501680679446 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 6.502122787142679e-05 0.0142466262053111 3.035452872698047e-05 2.9325766081138263e-06 6.84045570487912e-05 +Glycosyl hydrolase, all-beta [IPR013780] 4 8 2.259196106393567 0.0238711889255358 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 7.323130554406388e-05 1.0 1.0 0.0002086676392486 0.0002552418837429 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5e61a1f7cecddce0cc67655a87d0af2ef6680309 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 971, + "title": "Average number of proteins per term", + "value": 4.946446961894954 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..018b30ae684309521747108e4a7396b5fcfad9f2 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f93163134aa0a47b42c9e8045aaf3be1a12cce95 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,141 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycoside hydrolase superfamily [IPR017853] 0.87809420053771 2.7664835491334263 0.0056664443770335 0.9959851903855564 0.4785156457748975 16 P54802,P06280,Q8IW92,P16278,P04066,P10253,P04062,Q9BTY2,O00462 9 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.9069167935981328 2.4720646689752996 0.0134335213238978 0.999998019883579 0.4785156457748975 6 P09960,Q9UIQ6,P55786,Q9NZ08 4 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.9069167935981328 2.4720646689752996 0.0134335213238978 0.999998019883579 0.4785156457748975 6 P09960,Q9UIQ6,P55786,Q9NZ08 4 +Mitochondrial carrier domain superfamily [IPR023395] 0.6829024793083565 2.3406506941693817 0.0192501680679446 0.9999999936459102 0.4785156457748975 24 Q9BSK2,Q70HW3,O43772,Q96H78,Q9UBX3,Q9H2D1,Q9Y619 7 +Glycosyl hydrolase, all-beta [IPR013780] 0.8416230921023903 2.259196106393567 0.0238711889255358 0.9999999999352224 0.4785156457748975 8 P06280,P10253,Q9BTY2,P04066 4 +Porin domain superfamily [IPR023614] 0.8813518104606566 2.0581749925596364 0.0395733382523593 1.0 0.4785156457748975 4 P45880,P21796 2 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.6770759532760522 1.941761516082675 0.0521659777184329 1.0 0.5152318140237778 19 Q06203,P28070,P25787,P28074,P49720,Q9NWL6,P28072,Q06210,P60900,P49721,P20618,Q99436 12 +Alpha/Beta hydrolase fold [IPR029058] 0.579478107173564 1.7894571734957154 0.0735412187100101 1.0 0.5712681869393591 25 Q9UMR5,Q8NCC3,Q9H6V9,Q4J6C6,Q8NCG7,P10619,Q9H3G5,Q9HB40,Q9NUJ1,P50897,P42785 11 +DCN1-like, PONY binding domain [IPR042460] 0.8102431405434726 1.766490796742742 0.0773135442394765 1.0 0.5864957145041543 4 Q8IWE4,Q92564 2 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.7950089169407227 1.7031297277541728 0.0885437937746125 1.0 0.6210044209296341 4 Q99797,P42892 2 +SNARE [IPR010989] 0.7586531808627088 1.698950260686795 0.089328555797377 1.0 0.6210044209296341 5 O60499 1 +Galactose mutarotase-like domain superfamily [IPR011013] 0.7756367524054745 1.6221834095986511 0.1047640828883103 1.0 0.6397856885820711 4 P10253 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.9290478255106916 1.5195476937179797 0.1286246925293077 1.0 0.6979581249046817 3 P54802 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.6669740023530372 1.4765126567660574 0.1398063200361741 1.0 0.6979581249046817 7 P31930,P22695,Q10713,O43847 4 +Galactose-binding-like domain superfamily [IPR008979] 0.6343236999966141 1.4581794442092804 0.1447910881636818 1.0 0.6979581249046817 13 O00462,Q8IW92,P16278,Q15375,O14786 5 +Histidine phosphatase superfamily [IPR029033] 0.6619823010408004 1.4402487038661602 0.1497970483870849 1.0 0.6979581249046817 6 Q9NPH0,P11117 2 +NagB/RpiA transferase-like [IPR037171] 0.6561512572202226 1.414493596209726 0.1572170263020722 1.0 0.6979581249046817 6 P49770,O95336,Q9UI10 3 +HSP40/DnaJ peptide-binding [IPR008971] 0.6895729326081634 1.4029383306588632 0.1606352294462696 1.0 0.6979581249046817 5 Q9UBS4,Q96EY1 2 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5491177645069832 1.385518409918312 0.1658940071736576 1.0 0.6979581249046817 22 Q8NBM8,P31150,Q6QHF9,Q9H9P8,P50336,Q8NB78,Q6NUM9,Q96CU9,Q8NCN5,Q9UHG3 10 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6439557792719828 1.3605196000889186 0.1736655547543457 1.0 0.6979581249046817 6 P04350,Q9BUF5,Q13509 3 +NAP-like superfamily [IPR037231] 0.887349953831949 1.3603343585239454 0.1737241403345961 1.0 0.6979581249046817 3 Q01105,P55209 2 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.6976796128648528 1.2935525293083745 0.1958200285453906 1.0 0.7285105276535412 4 Q8TC07 1 +Death-like domain superfamily [IPR011029] 0.6163966827684297 1.2381410227731198 0.2156637752400834 1.0 0.7576322586511801 6 Q9UDY8 1 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.7576322586511801 5 O95486,Q15437 2 +Gelsolin-like domain superfamily [IPR036180] 0.6509195744961428 1.2357215726944593 0.2165620758903073 1.0 0.7576322586511801 5 O95486,Q15437 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.7576322586511801 3 P01889,P10321 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.7576322586511801 3 P01889,P10321 2 +Initiation factor 2B-like, C-terminal [IPR042529] 0.6813604850886481 1.2245561649885852 0.2207424924460319 1.0 0.7576322586511801 4 Q9UI10 1 +Tubulin, C-terminal [IPR023123] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.7576322586511801 5 P04350,Q9BUF5,Q13509 3 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.7576322586511801 5 P04350,Q9BUF5,Q13509 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.7576322586511801 5 P04350,Q9BUF5,Q13509 3 +Immunoglobulin-like fold [IPR013783] 0.4569162315493036 1.2014202532032985 0.2295882236641448 1.0 0.7699309522603602 28 P04439,P10321,Q9Y6N7,P01889,Q15375,Q9Y624,Q8IZA0,O00462,Q9UDY8,Q08722 10 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5892296360519 1.1378638646222805 0.2551773322045028 1.0 0.7902836966154835 8 P33527,Q9NUT2,P08183 3 +Fibronectin type III superfamily [IPR036116] 0.6585556493813451 1.1283352790327967 0.2591783496557767 1.0 0.7902836966154835 4 Q9Y6N7,Q15375 2 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9864615384615384 1.1215086267211023 0.2620714215346917 1.0 0.7902836966154835 2 O43657 1 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.5834056959209065 1.0913587659701929 0.275115048770135 1.0 0.8070595539450185 6 A1L0T0,Q8IXJ6 2 +Haem oxygenase-like, multi-helical [IPR016084] 0.9741538461538436 1.078993888763519 0.2805904519777957 1.0 0.8074862874081065 2 P30519 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.5727548021257776 1.0748896080138477 0.2824241551419426 1.0 0.8074862874081065 9 P52756,P35637,Q92804,Q01844 4 +ARFGAP/RecO-like zinc finger [IPR037278] 0.810710987996308 1.069527160505567 0.2848321970056067 1.0 0.8074862874081065 3 Q8N6T3,Q96P47 2 +ArfGAP domain superfamily [IPR038508] 0.810710987996308 1.069527160505567 0.2848321970056067 1.0 0.8074862874081065 3 Q8N6T3,Q96P47 2 +Prefoldin [IPR009053] 0.5575553903318857 0.9836654037089833 0.3252800555765165 1.0 0.8606183486779224 7 Q9UHV9,Q9NQP4,P61758,Q9UBK9 4 +Immunoglobulin-like domain superfamily [IPR036179] 0.5380157773276646 0.9775175011693812 0.3283130177643016 1.0 0.8623230623429943 13 P04439,P10321,Q9Y6N7,P01889,Q9Y624,Q9UDY8,Q08722 7 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.555788976183433 0.9757310960093968 0.3291977382147575 1.0 0.8623230623429943 7 O15173,O43169 2 +BAG domain superfamily [IPR036533] 0.7842413050169301 0.9707433111048228 0.3316761183357091 1.0 0.8639806673910109 3 O95817,O95429 2 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.5092962298670343 0.9663447024796884 0.3338717244011739 1.0 0.8639806673910109 18 O15217 1 +MIT domain superfamily [IPR036181] 0.7783933518005559 0.9491082405154144 0.3425655636923999 1.0 0.8711149101570299 3 Q6PHR2,Q8N0X7 2 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.8758801173643741 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.8758801173643741 2 P05067 1 +E2 domain superfamily [IPR036176] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.8758801173643741 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9258461538461492 0.9147076341436384 0.3603451355420981 1.0 0.8758801173643741 2 P05067 1 +Cytochrome P450 superfamily [IPR036396] 0.9141538461538408 0.8757308913271216 0.3811763476014924 1.0 0.8791501983872901 2 Q6UW02 1 +K Homology domain, type 1 superfamily [IPR036612] 0.4475417494131841 0.8626228479427516 0.3883448640476559 1.0 0.8886902773591945 24 Q9Y2W6,Q92945,Q9Y6M1,P51114,Q9NQT5,Q96AE4,Q96PU8,Q96I24,Q07666 9 +Band 7/SPFH domain superfamily [IPR036013] 0.5240434468021608 0.8407013319619788 0.4005152742096665 1.0 0.9047795780684944 8 P27105 1 +Ferritin-like superfamily [IPR009078] 0.8926153846153788 0.8049522723927034 0.4208472221519204 1.0 0.9194509094364772 2 P02792 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.5798016214139031 0.8021786039007127 0.4224496512054081 1.0 0.9194509094364772 4 P11717,P20645 2 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.5155892507271951 0.7967590199805695 0.4255909993717326 1.0 0.92035322176366 7 Q96CX2,Q08380,P52739 3 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.732411097415777 0.7822447793302257 0.4340707326597899 1.0 0.9285969416756272 3 Q99797 1 +ESCRT assembly domain [IPR037202] 0.8710769230769244 0.7357110117180639 0.461906586790537 1.0 0.948136933645392 2 Q9H9H4 1 +Chloride channel, core [IPR014743] 0.7173992908854291 0.7293440734190008 0.4657912188625173 1.0 0.948136933645392 3 P51797 1 +Kringle-like fold [IPR013806] 0.8621538461538423 0.7075395264029722 0.4792312584326796 1.0 0.948136933645392 2 Q9UBV2 1 +Fibronectin type II domain superfamily [IPR036943] 0.8621538461538423 0.7075395264029722 0.4792312584326796 1.0 0.948136933645392 2 Q9UBV2 1 +XPC-binding domain superfamily [IPR036353] 0.8483076923076909 0.6644886981656425 0.5063775800801831 1.0 0.9632899963854996 2 P54725 1 +SH3-like domain superfamily [IPR036028] 0.3823086556572428 0.658887796019742 0.5099678232180413 1.0 0.9632899963854996 28 Q14847,P46108,Q9UQB8,P46109,Q9NZW5 5 +Immunoglobulin E-set [IPR014756] 0.4705647066190001 0.6347688306170145 0.5255791947594173 1.0 0.9685742542053084 12 A6NIH7 1 +Proteasome activator superfamily [IPR036252] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.9761667041131348 3 Q9UL46 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.9761667041131348 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.6824701026821223 0.6102740711811001 0.5416802699465517 1.0 0.9761667041131348 3 Q9UL46 1 +Phosphoglycolate phosphatase-like, domain 2 [IPR023198] 0.8224615384615364 0.5865403139597393 0.5575124786007621 1.0 0.9824766183690382 2 Q08623 1 +Thioredoxin-like superfamily [IPR036249] 0.3605014064538979 0.581001303850422 0.5612395747945658 1.0 0.9838989719183986 47 O15217,O95881 2 +SH2 domain superfamily [IPR036860] 0.4591117575023936 0.5727286084591061 0.5668284638848915 1.0 0.987887781897676 11 P42224,P46108,P46109 3 +G protein alpha subunit, helical insertion [IPR011025] 0.5200123152709271 0.5698034934046964 0.5688109858846961 1.0 0.987887781897676 4 P04899,P63096,P08754 3 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8123076923076753 0.556874051867798 0.5776134844284848 1.0 0.987887781897676 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8123076923076753 0.556874051867798 0.5776134844284848 1.0 0.987887781897676 2 Q15392 1 +CAP Gly-rich domain superfamily [IPR036859] 0.6633018613356467 0.5478146956190146 0.5838191469222536 1.0 0.987887781897676 3 Q99426 1 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0.6451215758695013 0.4908265410548116 0.6235491364254138 1.0 0.9933560463525222 3 P52292,P52294 2 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.7870769230769084 0.485793547900673 0.6271135493451041 1.0 0.9933560463525222 2 Q15375 1 +Phosphoribosyltransferase-like [IPR029057] 0.4390018484288239 0.4753189773177317 0.6345596347202229 1.0 0.9955953312470536 6 Q06203,O60256,P00492,P07741,Q14558 5 +Caspase-like domain superfamily [IPR029030] 0.7824615384615206 0.4732284553958537 0.6360501985913916 1.0 0.9957081334759298 2 Q9UDY8 1 +Aldolase-type TIM barrel [IPR013785] 0.4324323473487547 0.4717117913660845 0.637132519548735 1.0 0.9957081334759298 13 P43490 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.4613756041523395 0.4537192584357009 0.6500309038138472 1.0 1.0 5 P46020 1 +EB1, C-terminal domain superfamily [IPR036133] 0.7729230769230782 0.4477190574339796 0.6543559660981992 1.0 1.0 2 Q15555 1 +Sec7 domain superfamily [IPR035999] 0.7720000000000021 0.4452840085316692 0.6561145229101968 1.0 1.0 2 Q92538 1 +Sec7, C-terminal domain superfamily [IPR023394] 0.7720000000000021 0.4452840085316692 0.6561145229101968 1.0 1.0 2 Q92538 1 +Ribosomal protein S10 domain superfamily [IPR036838] 0.7655384615384642 0.4284091589161856 0.668353257674543 1.0 1.0 2 Q96GC5 1 +Cyclin-like superfamily [IPR036915] 0.4771529596755297 0.4187525907826865 0.6753969562619393 1.0 1.0 4 P06400 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.7572307692307579 0.4071618337113596 0.6838891312593629 1.0 1.0 2 P49356 1 +EF-hand domain pair [IPR011992] 0.3448671481888312 0.379276646302731 0.7044824399704337 1.0 1.0 53 P80303,Q14257,O75071,Q9H4M9,P30626,Q66K14,Q14651,Q9NWM8,P0DP25,Q02818,Q9Y680,P31949,O43852 13 +HAD-like superfamily [IPR036412] 0.384938149082365 0.3787743457907691 0.7048554394576982 1.0 1.0 21 Q08623,Q969T7,Q9HD20,Q05D32,Q5TFE4 5 +HAD superfamily [IPR023214] 0.384938149082365 0.3787743457907691 0.7048554394576982 1.0 1.0 21 Q08623,Q969T7,Q9HD20,Q05D32,Q5TFE4 5 +GOLD domain superfamily [IPR036598] 0.4638931870603943 0.3756489916632662 0.7071778637050774 1.0 1.0 4 Q9Y3B3 1 +Profilin superfamily [IPR036140] 0.7418461538461578 0.3692071912179709 0.7119732961446585 1.0 1.0 2 P07737 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.400200384061322 0.3688817222483928 0.7122158876215563 1.0 1.0 87 Q8IYR2,P49321,Q9Y3D6,Q9UBV2,P13674,Q9BXJ9,O75718,Q6ZXV5,O00231,Q15785,P30260,Q96EK5,Q9UJX4,O75153,Q13042,Q9NSK0,Q6DKK2,Q14CX7,Q8IWR0,Q99614,Q6PGP7,Q9Y262,O15460,Q7L5D6,Q32P28,Q5R3I4 26 +Longin-like domain superfamily [IPR011012] 0.4052092196229804 0.3490844432461622 0.727025915322431 1.0 1.0 12 Q9BXS5,P61966,Q92572,O15498 4 +UBA-like superfamily [IPR009060] 0.383169149188674 0.3468490287443224 0.7287047412726884 1.0 1.0 20 P54725,Q9H1I8,P54727,Q9BSL1,Q5T6F2 5 +Dynein light chain superfamily [IPR037177] 0.7276923076923058 0.3359668969371918 0.7368958294050554 1.0 1.0 2 Q96FJ2 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.7233846153846095 0.3261825331736791 0.744286255852616 1.0 1.0 2 Q9BYT8 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.5837463760438456 0.3183940167480265 0.7501860762658121 1.0 1.0 3 P46020 1 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.3013686201149501 0.3176960262640864 0.7507155257621603 1.0 1.0 33 Q9BV86,Q9UET6 2 +ANL, N-terminal domain [IPR042099] 0.3932797351473825 0.3039504137508357 0.7611656689612065 1.0 1.0 7 Q9UKU0 1 +Annexin superfamily [IPR037104] 0.4099788468673957 0.2818686820521908 0.7780442043425002 1.0 1.0 5 P50995,P04083 2 +HSP90, C-terminal domain [IPR037196] 0.4152658367644439 0.2360783280961267 0.8133718903580061 1.0 1.0 4 P08238 1 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 1.0 2 Q15118 1 +Isoprenoid synthase domain superfamily [IPR008949] 0.4065329400778505 0.2144805001234974 0.830172371802318 1.0 1.0 4 P37268 1 +Ubiquitin-conjugating enzyme/RWD-like [IPR016135] 0.3673761126237443 0.2086698425282337 0.8347059840379929 1.0 1.0 10 Q99816,P61088,P49427 3 +MoaB/Mog-like domain superfamily [IPR036425] 0.6572307692307691 0.1969293094891055 0.8438828571157355 1.0 1.0 2 Q8NFF5 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 1.0 2 P42224 1 +STAT transcription factor, coiled coil [IPR015988] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 1.0 2 P42224 1 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 1.0 2 P42224 1 +Ribokinase-like [IPR029056] 0.5198439027923366 0.1797444824354149 0.85735317018632 1.0 1.0 3 Q9BRR6 1 +Ubiquitin-activating enzyme [IPR035985] 0.3557336621455026 0.179552572664831 0.8575038409624269 1.0 1.0 8 Q9GZZ9,Q13564,Q8TBC4,A0AVT1,O95396,P22314,Q9UBE0 7 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.3860481973537309 0.1683637927991199 0.8662970906204399 1.0 1.0 4 Q16881 1 +PDZ superfamily [IPR036034] 0.3403603953964004 0.1662153919626941 0.8679874469032289 1.0 1.0 21 Q6ZWJ1,O00560,P57105,Q9H8Y8,Q9NZW5 5 +Moesin tail domain superfamily [IPR008954] 0.4872268390273976 0.1273670667413462 0.8986498808495891 1.0 1.0 3 P26038,P35241 2 +Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591] 0.6033846153846214 0.1223843981649246 0.9025945940848974 1.0 1.0 2 Q9Y399 1 +Class I glutamine amidotransferase-like [IPR029062] 0.332752207930458 0.1169804457547308 0.9068755491065292 1.0 1.0 8 Q92820 1 +Rho GTPase activation protein [IPR008936] 0.3302935578442288 0.0960327951060825 0.92349452619469 1.0 1.0 11 Q86VI3,O00459,Q9H0H5 3 +SCP2 sterol-binding domain superfamily [IPR036527] 0.4376731301939108 0.0712851997969484 0.9431707741126832 1.0 1.0 3 P51659,Q6YN16 2 +eRF1, domain 2 superfamily [IPR042226] 0.5446153846153947 0.0708175961379739 0.9435429272921548 1.0 1.0 2 P62495 1 +Ribosomal protein P1/P2, N-terminal domain [IPR038716] 0.5144615384615443 0.0544825395876206 0.956550719316841 1.0 1.0 2 P05386 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.5104615384615506 0.0527422904816147 0.9579372429669696 1.0 1.0 2 A0AVT1 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.5086153846153935 0.0519698111248363 0.9585527481277774 1.0 1.0 2 P29692 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.5086153846153935 0.0519698111248363 0.9585527481277774 1.0 1.0 2 P29692 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.4895384615384643 0.0450457244244358 0.9640708631010746 1.0 1.0 2 Q96AX1 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.3785780240073917 0.0355599363811939 0.9716332542388416 1.0 1.0 3 Q9H0C8,Q15750 2 +AF1104-like superfamily [IPR036075] 0.4061538461538489 0.030883287438112 0.975362618258361 1.0 1.0 2 Q9NVE7 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.36411203447215 0.030693015447555 0.9755143614052612 1.0 1.0 3 Q13188,Q13043 2 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.3065945192087939 0.0304213275414057 0.9757310358077936 1.0 1.0 13 Q15436,Q9Y281,O95486,Q15437 4 +Integrin domain superfamily [IPR032695] 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 +Cytidine deaminase-like [IPR016193] 0.3624615384615349 0.0290247599749941 0.9768448433061808 1.0 1.0 2 P32321 1 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.3609230769230702 0.0289899456759871 0.9768726094138248 1.0 1.0 2 Q9HC38 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.3550769230769151 0.0288705121461401 0.9769678637130028 1.0 1.0 2 Q8TBC4 1 +Arp2/3 complex subunit 2/4 [IPR034666] 0.3015384615384556 0.0283786714896789 0.9773601350351536 1.0 1.0 2 P59998 1 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.297230769230758 0.0283657777697422 0.9773704185953428 1.0 1.0 2 P38606 1 +Tautomerase/MIF superfamily [IPR014347] 0.2735384615384519 0.0283235546274284 0.9774040942581316 1.0 1.0 2 P14174 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.3431825176977588 0.0255844183693989 0.979588814342884 1.0 1.0 3 P35611,Q9UEY8 2 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.2803939673745824 0.0190181627408164 0.9848266162579404 1.0 1.0 3 P30876,Q9NW08 2 +Zinc finger, CCCH-type superfamily [IPR036855] 0.2737361282367453 0.0024674913950044 0.9980312287098274 1.0 1.0 8 Q9NW64,P42694,Q9NXH9,Q8IWR0,Q6P158,Q8WU90,Q86VM9 7 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d1ef98a4f392e5c8c4ff352d67a556b4ceee72b5 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase delta subunit 3 superfamily [IPR041913]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like [IPR012347]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Quinolinate phosphoribosyl transferase, N-terminal domain superfamily [IPR037128]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPB6/omega subunit-like superfamily [IPR036161]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOCS box-like domain superfamily [IPR036036]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL8A", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATXN10", "AURKA", "AURKB", "B3GAT3", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAS3", "BCKDHA", "BCL2L13", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD2", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPV", "CEP170", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUX1", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCK", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAT1", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GORASP2", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFRD1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAGED2", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED21", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDUFA10", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PICK1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMU1", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX16", "STX5", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS16", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRAP73", "WRN", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFR", "ZFYVE16", "ZNF131", "ZNF280C", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ABHD10", "ACP2", "ACP6", "ACSL6", "ADD1", "ADD3", "ADPGK", "AGAP3", "ANAPC5", "ANXA1", "ANXA11", "AP1M1", "AP1S1", "AP3S1", "APP", "APRT", "ARFGAP1", "ARPC4", "ASCC2", "ASNSD1", "ATP13A1", "ATP6V1A", "BAG3", "BAG4", "BAIAP2", "CALM3", "CALU", "CD47", "CDC16", "CDC27", "CDC34", "CFL2", "CLCN6", "CLUH", "CPVL", "CRK", "CRKL", "CRTAP", "CTDSPL2", "CTSA", "CYB5B", "CYP20A1", "DAGLB", "DCTD", "DCUN1D3", "DCUN1D4", "DHCR24", "DHX57", "DNAJA3", "DNAJB11", "DYNLL2", "ECE1", "EEF1D", "EFCAB14", "EHD1", "EIF2B2", "EIF2B4", "EIF3L", "EPHA7", "ERAP1", "ETF1", "EWSR1", "EXOSC3", "F11R", "FDFT1", "FIS1", "FKBP14", "FKBP7", "FLAD1", "FNTB", "FOXRED1", "FTL", "FTSJ1", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "GAA", "GBA", "GBF1", "GDI1", "GET4", "GFPT1", "GGH", "GLA", "GLB1", "GLB1L2", "GLOD4", "GNAI1", "GNAI2", "GNAI3", "GORASP2", "GSTA4", "HELZ", "HLA-A", "HLA-B", "HLA-C", "HMOX2", "HPRT1", "HSD17B4", "HSDL2", "HSP90AB1", "IGF2BP2", "IGF2R", "ILKAP", "ILVBL", "IQGAP3", "ITGAV", "KCTD12", "KDM1B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIFBP", "KLC4", "KPNA1", "KPNA2", "L2HGDH", "LASP1", "LDAH", "LGALS3BP", "LNPEP", "LTA4H", "M6PR", "MALT1", "MANBA", "MAPRE2", "MIF", "MIPEP", "MOCS3", "MPP6", "MRPL48", "MRPS2", "MSN", "NAA15", "NAA25", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NASP", "NLN", "NPEPPS", "NRDC", "NRP1", "NT5C3B", "NT5DC1", "NTMT1", "NUCB1", "NUCB2", "P3H1", "P4HA1", "P4HA2", "PANK4", "PAOX", "PCYOX1", "PCYOX1L", "PDK1", "PDPR", "PFDN2", "PFDN4", "PFN1", "PGLS", "PGRMC2", "PHKA1", "PIK3R2", "PLA2G15", "PLS1", "PMPCA", "POLR2B", "POLR3B", "PPAT", "PPOX", "PPT1", "PPT2", "PRCP", "PREPL", "PRPSAP1", "PRPSAP2", "PSMA2", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSME2", "PUDP", "QKI", "RACGAP1", "RAD23A", "RAD23B", "RB1", "RBM22", "RBM5", "RCN2", "RDX", "RETSAT", "ROBO1", "RPLP1", "S100A11", "SAE1", "SCPEP1", "SDCBP", "SEC23A", "SEC23B", "SEC24A", "SEL1L", "SET", "SIRT2", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A44", "SMYD4", "SPART", "SRI", "STAT1", "STK3", "STK4", "STOM", "STX10", "STXBP4", "SYNJ2BP", "TAB1", "TAF15", "TBC1D15", "TBC1D9B", "TBCB", "TDRKH", "TMED7", "TMTC3", "TOMM34", "TRMT1", "TSG101", "TSPAN6", "TTC1", "TTC19", "TTC37", "TTC38", "TUBB3", "TUBB4A", "TUBB6", "TXNDC12", "TXNRD1", "UBA1", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBE2N", "ULK3", "UNC119B", "UQCRC1", "UQCRC2", "UXT", "VBP1", "VDAC1", "VDAC2", "VPS33A", "VPS37B", "YKT6", "ZC3H15", "ZC3H18", "ZC3H7A", "ZNF131"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..218a6a10322ff41b2a92592ed43687f175aeb865 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0c467f4fe532f3209b91acc5d46c457c8b535271d2320190fd55a43be7316e3 +size 71624 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..113c6ab00505f9befa9d44e5160113101d22d412 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fd7221233739c9c51547600ec5779c330cf70a44 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..12815de51b0c395b3793de4d737a62739d34d9e8 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.7756232686980628 0.9388875846934616 0.347788464183173 0.8190519513508608 0.6515456954896355 3 Q14517,Q04721 2 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c1d9e005a933c3e972c32dd067d8b365de1df7ff --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "FAT1", "NOTCH2", "SLIT2"], "leading_proteins": ["FAT1", "NOTCH2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..de9f0bbbf0a259e24615d336d583c360d0fc44bd --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0104fcacca7dbcad4e6996a65a146954bfed38d6346ba2f16397d7f1019b863c +size 190330 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..89347332fd727e794f5dc31a862dff01327a7f4e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ed9511173d92f23870a9d6f06d62a6b34680b7b1 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8c2567cb89efc48e8a09948c819c37fee3e56a44b03dd1fd6f5fb0d805f9d6d +size 142758 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9f68ac4beaa86635bcd89e471862f7b286b4d4f6 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7902ba77a2d575a4f127eca8ab3ca118a96f0ae902669269f5774263bab12ea +size 148391 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8aa3505b0ebd2ce58cbba994bb19558e9c6c0cc5 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4260b93607f81b5789b8e8e043360bed567014493a00cdd0e2fb10e080ef8d6 +size 75523 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a70e7d1ab67d2fa0e82efd4cde7824ed1b34a62a --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 7 24 2.3406506941693817 0.0192501680679446 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 6.502122787142679e-05 0.0142466262053111 3.035452872698047e-05 2.9325766081138263e-06 6.84045570487912e-05 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c2a89aac534f392b3458de45c6604c46796b3b14 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 80, + "title": "Average number of proteins per term", + "value": 5.3875 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2951d323baccf783030f1f24519ef110f5285768 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db45733217377fdbb39e1e02d89d0d23be2d1a37 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.6829024793083565 2.3406506941693817 0.0192501680679446 0.7888167883788152 0.32158700953507 24 Q9BSK2,Q70HW3,O43772,Q96H78,Q9UBX3,Q9H2D1,Q9Y619 7 +HEAT repeat [IPR000357] 0.5108561497147477 0.7722704775405117 0.4399542469994484 1.0 0.8531056956138413 6 P30154,P30153,Q6PJG6 3 +Tetratricopeptide repeat [IPR019734] 0.3769952704233232 0.7286083164973305 0.4662412898341581 1.0 0.8531056956138413 46 Q99614,P49321,P50542,Q6ZXV5,Q6PGP7,Q9NSK0,Q15785,Q6DKK2,Q13451,O15460,P30260,P13674,O00170,A0AVF1,Q9BXJ9,Q9UJX4,Q13042 17 +Atypical Arm repeat [IPR032413] 0.6451215758695013 0.4908265410548116 0.6235491364254138 1.0 0.941206243661002 3 P52292,P52294 2 +Annexin repeat [IPR018502] 0.4099788468673957 0.2818686820521908 0.7780442043425002 1.0 0.9947590219584056 5 P50995,P04083 2 +Kinesin light chain repeat [IPR015792] 0.6963076923076704 0.2683990323280565 0.7883921842871837 1.0 0.9947590219584056 2 Q9NSK0 1 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.3665834584433744 0.0314396726629626 0.9749189025679836 1.0 1.0 3 Q9P253 1 +Pumilio RNA-binding repeat [IPR001313] 0.2957833179439881 0.0198200631396254 0.9841869129556182 1.0 1.0 3 Q86U38,Q14671 2 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f9c9cec67bcb5eae3fe083b92fd91cf86c0dec8c --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANKS1A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARPC1A", "ARVCF", "ASB6", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC16", "CDC20", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN3", "CNOT10", "COA7", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EHMT2", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GRWD1", "GTF2I", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HTT", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGAV", "JUP", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KIDINS220", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "L3MBTL2", "LARP1", "LASP1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP2", "RABEPK", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STRN3", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIM32", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "UACA", "UNC45A", "USO1", "UTP15", "UTP18", 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sha256:3967c919374fbfa134006216305b2ff4cc15add291c6c34313d85a18750c42ef +size 222815 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cfbf3d8ef23d6a4ad9df2d25a1af06bf7ab8818d --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,68 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Membrane lipid metabolic process 14 35 3.448156324918827 0.0005644272599651 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 3.322546112010445e-07 0.0025697820274141 2.04103902831378e-05 6.906591626136046e-06 7.095541964861969e-05 +Organophosphate ester transport 11 33 3.15839196574159 0.0015864209729552 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0006528290781577 0.3175327074700926 0.0009958002736197 2.0650565379923648e-05 0.0004233190867733 +Lytic vacuole organization 10 25 3.130523873382397 0.0017449481567388 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 1.401510679789678e-05 0.0029449884503582 1.6656079796260948e-06 1.6234275952418324e-06 0.0001336207264704 +Sphingolipid metabolic process 12 27 2.949446964409681 0.0031834320638426 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 1.2654749949655175e-06 0.0010451763347091 3.373946879830246e-05 1.7044894323091794e-05 0.0001778981760189 +Membrane lipid catabolic process 7 10 2.7427007135781287 0.0060936196461884 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 1.3056417075771692e-09 0.0040679264544396 1.076789969731225e-06 1.1057177661886282e-08 2.326893237930348e-06 +Neuromuscular process 5 28 2.6940671115256074 0.0070585950516681 6.682038834951456 25.487864077669904 0.5107907507501308 0.3958015985368521 2.5973040014911133 3.0533044809467955 1.2106508695866462 0.3144907539964949 0.0013901358269778 1.0 0.0038034373632918 0.0053374430593766 0.1029946911945799 +Glycosphingolipid metabolic process 4 7 2.6173731843222363 0.0088609407007902 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.0003310814372637 1.0 0.0405463165390607 0.0011317572349641 0.0210083519091097 +Ceramide catabolic process 4 6 2.614920858593417 0.0089248132464188 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 1.5185857673641351e-06 0.0561990347849709 0.0001833288791406 5.744803073006659e-06 0.0001636284502288 +Glycolipid catabolic process 4 6 2.611469281100988 0.0090154086930522 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 1.5185857673641351e-06 1.0 0.0057815105752346 5.744803073006659e-06 0.0001636284502288 +Retrograde transport endosome to golgi 6 37 2.5697578302937987 0.0101769629652368 8.844660194174757 34.00485436893204 0.6408100896550543 0.5235396612667444 4.365036019054001 3.8497226893137166 0.9745365654790862 0.3516062635557995 0.069054796469328 0.3306605597140526 0.1926825508424764 0.0040824974236727 0.0496304198234271 +Inorganic anion transport 11 30 2.485657522385877 0.0129312343903744 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.001751663246285 0.0432831882721129 0.029330571697131 0.0014147813856964 0.000113660359535 +Lysosomal lumen acidification 2 5 2.468101687626516 0.0135831726983268 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0009412478616896 1.6752670706047648e-05 0.0001384716540127 0.0020533662966424 0.0143213925416526 +Vacuolar acidification 4 10 2.442186167736262 0.0145986162297844 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0042285888968899 8.090961716756818e-05 0.0006517968090871 5.510228275490696e-05 0.0013860636450687 +Protein catabolic process in the vacuole 3 6 2.426716098646311 0.0152361734450587 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0004479915205189 0.0919337377678228 0.0008978593047678 0.0012358112224234 0.0146945119164238 +Lysosomal protein catabolic process 3 6 2.426716098646311 0.0152361734450587 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.000291319303006 0.083126337411673 0.0006517968090871 0.0008110696558398 0.0100261737850475 +Glycoside catabolic process 4 5 2.399492319716144 0.016417824229516 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 7.714729806398837e-06 1.0 0.075113296023457 4.402192379002321e-07 1.3632546196600551e-05 +Vitamin transmembrane transport 3 6 2.3990137298723946 0.0164392982769252 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0024567571854954 0.0697581245313758 0.0003712110430798 0.0052676758380378 0.0050247198439474 +Monovalent inorganic cation homeostasis 6 30 2.390941661229605 0.0168052229458748 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0470632874722157 0.0051240399378157 0.0338721796728873 0.0019675889741868 0.0256850446627721 +Regulation of lysosomal lumen ph 3 7 2.369391599168726 0.0178173772346847 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0024567571854954 4.557535944516599e-05 0.0003712110430798 0.0003832983840783 0.0050247198439474 +Cellular response to oxygen levels 12 36 2.3689075097449006 0.0178407143152543 8.393203883495145 36.271844660194176 0.9126927578207408 0.4163034805851183 3.607671495386698 4.048118764224637 0.9088125816374436 0.3418533733797396 0.0039990505604857 0.4072806445693771 0.0207919883966976 0.0048720745390507 0.0064078543846849 +Liposaccharide metabolic process 6 15 2.356390308458838 0.0184535168206718 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 9.406832054778249e-05 1.0 0.0186371594327644 0.0004948612164357 0.0069005748974321 +Entry into host 8 31 2.3463690117283496 0.0189573283386959 7.968446601941747 31.24514563106796 0.6061616104105989 0.3954837799611526 3.566493820193545 3.4119437173329663 1.31706945612869 0.333413728218646 0.0954554928929811 1.0 0.2282562036879738 0.0770567400392524 0.037853960521189 +Secondary alcohol metabolic process 17 40 2.337511047311841 0.0194126271927905 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 0.0002085510469977 0.0653891722063119 0.0015360029240361 0.0002607826129741 1.811191882972623e-05 +Peptide catabolic process 6 11 2.2536615618137983 0.0242174672609467 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 2.0046921129068102e-05 0.0875404472016038 0.0007685743700876 4.149873839794316e-06 1.9425748581830696e-05 +Acute inflammatory response 1 5 2.251996513904824 0.0243224923176921 1.4466019417475728 4.689320388349515 0.9285034691739726 0.2315648833934721 0.949993922717463 0.5957637867345709 1.213201626775504 0.2269795845272838 0.0729450524117466 0.1093006244161378 0.0224191931510111 0.1154739846724814 0.329764304368849 +Regulation of cellular ph 6 21 2.2413297115480018 0.0250047257522669 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0128831683681083 0.0016453439849387 0.0118453859760714 0.0001703692479783 0.0023826734310202 +Regulation of ph 6 21 2.2413297115480018 0.0250047257522669 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0157698814740867 0.0019537982219709 0.0139156518076104 0.000249328663123 0.0034977054462546 +Vitamin transport 4 9 2.222944599397324 0.026219535900662 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0009269285327108 0.1093006244161378 0.0015498580582828 0.00251045639703 0.0053941913939985 +Sphingoid metabolic process 2 5 2.219747718077184 0.0264358976928642 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0006940358493172 0.0009934566258862 0.0001014210629885 0.0015206572897169 0.000939912047649 +Cellular monovalent inorganic cation homeostasis 6 26 2.1988073066956404 0.027891626741876 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0267394695546039 0.003086924646434 0.0212914346042941 0.0006748300938215 0.0093343481979524 +Macromolecule depalmitoylation 3 5 2.194939982141149 0.0281679032884372 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0201641140768861 0.0014481500629001 0.0057815105752346 0.0026887292270871 0.0020484591711739 +Neuromuscular process controlling balance 3 11 2.1889066859781967 0.0286036230265525 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 0.001087555273715 1.0 0.02421661276018 0.002932051876052 0.0316693819105829 +Antigen processing and presentation of endogenous peptide antigen 5 7 2.18872421921724 0.0286168905623591 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 1.0 1.0 1.0 0.0042908003473226 2.860232281215099e-05 +Antigen processing and presentation of endogenous antigen 5 7 2.18872421921724 0.0286168905623591 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 1.0 1.0 1.0 0.0052676758380378 4.5707008677286863e-05 +Diol metabolic process 4 7 2.1833539295232867 0.0290097559010882 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0349220856805398 0.0742352733278267 0.0102498345034834 0.0569248849368824 0.0007664910713946 +Diol biosynthetic process 4 7 2.1833539295232867 0.0290097559010882 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0235417287368035 0.0607401038440192 0.0067896670197663 0.0388074443523606 0.0002552418837429 +Negative regulation of calcium ion transport 2 7 2.183258407966996 0.0290167856267271 2.378640776699029 8.815533980582524 0.865801675063994 0.3348216966365627 1.767376998119782 1.5264501163101216 0.996781239251156 0.2731835761958332 0.1070428504887252 0.134742527043449 0.2540772386550496 0.1658780833937837 0.1795821936355247 +Negative regulation of calcium ion transmembrane transport 2 7 2.183258407966996 0.0290167856267271 2.1067961165048543 7.601941747572815 0.9433101814663925 0.3101119054926485 1.594362771690279 1.170758660555987 1.028728108691548 0.2750664841729511 0.0479915779418294 0.0875404472016038 0.1693528922958147 0.0773660358903978 0.0630285368739531 +Regulation of nitric oxide synthase activity 3 6 2.170212905128566 0.0299907208919194 1.8980582524271843 6.400485436893204 0.8861714382596724 0.3064882013314778 1.014121704509923 0.9815283096291466 0.998778670456744 0.2492245557560045 0.0049532633265819 1.0 0.1693528922958147 0.0104402688493973 0.0122181482786312 +Phospholipid transport 5 15 2.159053597242813 0.0308460090435052 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0025002573500667 1.0 0.0132042256106822 0.0014327621348651 0.0372124324154063 +Response to testosterone 3 9 2.141438472312052 0.0322386952342688 2.2475728155339807 10.03883495145631 0.690187001340658 0.4274863813898081 1.531820711212588 1.9825566023437624 0.9062651039217045 0.3093778692857544 0.0016852344248444 1.0 0.239336332644921 0.0044816860022438 0.0457284836366409 +Ph reduction 4 13 2.1355558012103875 0.0327156372886825 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0148156372504834 0.0003140311505353 0.0024390672757694 0.0005176459432172 0.0019984956462376 +Sterol metabolic process 15 36 2.1253487026959648 0.0335575272348829 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 0.0050041888196956 0.3371313972628795 0.049541392930243 0.0046583321582055 0.0002296722917124 +Inflammatory cell apoptotic process 1 5 2.1249512079070314 0.0335906844163491 0.7427184466019418 4.271844660194175 0.8196229591104243 0.4092025816559291 0.8905220397339731 0.7333150524575415 0.8004660138819563 0.2829064873012414 0.2600649649267221 1.0 0.144637307685789 0.0569248849368824 0.1829832713301316 +Hormone metabolic process 6 32 2.124120262449008 0.0336600885800895 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0094201897878543 0.3746890061856052 0.0681445056645133 0.0094861113483563 0.1965892734213886 +Modified amino acid transport 3 6 2.115610927591385 0.0343779116918423 2.029126213592233 5.587378640776699 1.6181581718562612 0.1578136127091599 1.2124460606928238 1.444653995706506 0.7704353439327314 0.2037484924456972 0.005748311292322 0.0919337377678228 0.1774332758731671 0.0120645849010356 0.0146945119164238 +Locomotory behavior 8 31 2.1136727530030357 0.0345432272315693 7.186893203883495 29.01456310679612 0.367578136549174 0.4129867938447028 2.855164467106169 2.964970497634466 1.254834886476281 0.3178953925587394 0.0085406162485386 0.3685774959165274 0.0648492807338132 0.0084996601315941 0.0425004290732149 +Aminoglycan metabolic process 6 17 2.1099619948769943 0.0348616295716006 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0010001192499895 0.2588687133858448 0.0222198796395938 0.0007451547610873 0.0102726434609872 +Sterol homeostasis 7 11 2.108833902579938 0.0349589211302545 3.2597087378640777 11.594660194174756 0.7425754872590924 0.2773502445350785 1.6018884221780605 1.6170423171351411 1.3033948892752858 0.2615762483252933 0.157452225232446 1.0 0.3102657432506607 0.0133642522995781 0.0096898626624995 +Response to hepatocyte growth factor 3 5 2.1067362004005297 0.0351404524485281 1.83252427184466 5.682038834951456 0.22147406836211 0.5067944222688716 1.3469168089334904 1.8521485079710065 1.0288209560233612 0.3181783420506056 0.0309296413333845 1.0 1.0 0.0052676758380378 0.0050247198439474 +Negative regulation of leukocyte mediated immunity 4 5 2.0905224109885188 0.0365708973737819 1.4684466019417477 5.152912621359223 1.0166590601943912 0.2872549002772236 1.1850502896064032 1.2860024091145663 0.9722873313503664 0.2687277537722931 0.0575347279148438 1.0 0.1854358412925483 0.0138257504316944 0.0029149932554685 +Carbohydrate derivative catabolic process 13 35 2.089063575029733 0.0367020006888914 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 1.3028434837681203e-06 0.4243503559946278 0.0049705397344002 6.622529890770961e-07 0.0001288744682942 +Neuron projection arborization 2 6 2.0868780987474573 0.0368991551070181 2.1189320388349513 6.410194174757281 0.2997181931700579 0.5356389026564765 1.6063982583137093 1.2538070031432729 0.9306716986687408 0.3086593014216465 0.2600649649267221 1.0 1.0 0.0569248849368824 0.040555747021854 +Regulation of natural killer cell mediated immunity 4 6 2.0759626076422224 0.0378974094621189 1.9053398058252424 5.33252427184466 0.1935470825099924 0.4776968923010209 1.19191069217632 1.22419398365008 1.049644639210895 0.3147111439809284 0.2600649649267221 1.0 1.0 0.0063676045893722 0.0064441294348778 +Pyridine containing compound biosynthetic process 0 6 2.0696700776522854 0.038483250674322 1.1771844660194175 4.592233009708738 0.442191494479448 0.5006889660618573 1.0613070504301176 1.0375184471761203 0.8939647210170195 0.2921877271034155 0.2459935349754131 0.0697581245313758 0.1362380906066266 0.3100425591757577 0.529149365173115 +Pinocytosis 4 7 2.039522532267526 0.0413979047683104 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 0.2874289072085323 0.083126337411673 0.1611939416425752 0.0703212183088513 0.2193015556183544 +Cellular response to increased oxygen levels 2 6 2.036962435864936 0.0416538064950589 1.6504854368932038 6.385922330097087 1.138869139630967 0.2726341581961526 1.2184562719610088 0.8029653015671253 0.9206381175249092 0.2739573544488438 0.0201641140768861 0.0561990347849709 0.1105474823156849 0.0026887292270871 0.0184123703315846 +Prostate gland development 2 6 2.0325708696679308 0.0420958970393063 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.4423342558572057 0.1389130578490434 0.2613412907301976 0.1746199077901094 0.1921014614726791 +Regulation of cellular amine metabolic process 0 6 2.0287775409944624 0.0424809538357455 2.0728155339805827 5.388349514563107 -0.3725888626209068 0.5237947914041097 1.3915622410897246 1.1573572986223923 0.8560082743345332 0.2891275769194143 0.2170471788318353 0.0607401038440192 0.1191939669275513 0.2750191284248381 0.4793722842885909 +Amide transport 16 41 2.0275833333618274 0.0426027914423949 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 0.1127589601545807 0.1403881914917208 0.3851788136583873 0.1187596707915287 0.007106547208012 +Negative regulation of gliogenesis 2 6 2.027185963946096 0.0426433980489848 1.3470873786407769 5.104368932038835 0.7908721225635217 0.3008340423028514 0.9967988871839628 1.1559387979758486 1.13650278668033 0.2567959459302846 0.062532572490685 1.0 1.0 0.099708835751112 0.0900519583357078 +Negative regulation of immune effector process 6 9 2.023566305618462 0.0430147948415886 2.5970873786407767 9.104368932038836 0.7327967275062157 0.3846873769388228 1.645172774630188 1.6739814581235892 0.934270881833941 0.2788291164950996 0.157452225232446 1.0 0.3102657432506607 0.0133642522995781 0.0096898626624995 +Anion transmembrane transport 11 48 2.0022419149345017 0.0452587197168028 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0048836108120205 0.0164824785433421 0.0046116462239443 0.0004011920877429 0.0010960952474709 +N terminal protein amino acid modification 4 10 1.9884443719824203 0.0467625655191064 2.45873786407767 8.439320388349515 0.5804938412353885 0.4249038973587519 1.7696871423418874 1.4824892226959214 1.0345977331938565 0.310740936912418 0.0120817861419125 0.1178616319260966 0.0260710687649276 0.0033995973847004 0.0077027418898757 +Regulation of leukocyte degranulation 2 5 1.9764553552594903 0.0481032273857073 1.6699029126213591 6.470873786407767 0.5853711877145334 0.3457823611194687 1.4305158925119918 1.701406104268744 1.0992219708926214 0.2597166324139169 0.3391731546920363 1.0 0.1933613304033528 0.0157252402213966 0.0900519583357078 +Glial cell proliferation 2 6 1.9671471995612333 0.0491662431263817 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0676716593812939 1.0 0.2012104780589677 0.1075130907868997 0.0999700788291247 +Regulation of blood pressure 6 18 1.9613266331903088 0.0498409323671682 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0043925419926 0.2443632781182481 0.0023751027082345 0.0027943802514918 0.0223659228002449 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..263b85febd13b93112073634b8199ce3229196d1 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 6467, + "title": "Average number of proteins per term", + "value": 19.499149528374826 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..eaf140a8e1f18f4592609f34858ba3ffe80a1c6e --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82922512cb61fbc5b5b17943e78283f32444fdc1 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1739 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Membrane lipid metabolic process 0.7048399654456617 3.448156324918827 0.0005644272599651 0.9740395642115705 0.8982894305628181 35 P06280,Q8NCC3,P16278,P04066,P06865,Q13510,P17900,P50897,P04062,Q06136,P07602,Q8NBX0,Q9NZ01,O95470 14 +Organophosphate ester transport 0.6586570415822645 3.15839196574159 0.0015864209729552 0.999965256946332 0.8982894305628181 33 Q9BSK2,P61916,Q00169,Q14108,Q86VD7,Q9H2D1,P33527,P41440,Q8WTV0,Q8TB61,P08183 11 +Lytic vacuole organization 0.8032689570738514 3.130523873382397 0.0017449481567388 0.9999875580496352 0.8982894305628181 25 P54802,Q8N511,P11117,P50897,O75503,Q14108,P10253,O14773,Q9HC07,P04062 10 +Sphingolipid metabolic process 0.7325676173231337 2.9494469644096815 0.0031834320638426 0.999999998891318 0.8982894305628181 27 P06280,Q8NCC3,P16278,P06865,Q13510,P17900,P50897,P04062,Q06136,P07602,Q9NZ01,O95470 12 +Membrane lipid catabolic process 0.941240933707757 2.7427007135781287 0.0060936196461884 1.0 0.8982894305628181 10 P06280,Q13510,P04066,P17900,P50897,P04062,O95470 7 +Neuromuscular process 0.6722977942211663 2.6940671115256074 0.0070585950516681 1.0 0.8982894305628181 28 P17900,P05067,O75844,O14773,P04062 5 +Glycosphingolipid metabolic process 0.9363606016466296 2.6173731843222363 0.0088609407007902 1.0 0.8982894305628181 7 P06280,P17900,P16278,P04062 4 +Ceramide catabolic process 0.9431161848811388 2.614920858593417 0.0089248132464188 1.0 0.8982894305628181 6 P06280,P17900,P04062,Q13510 4 +Glycolipid catabolic process 0.9422339795136366 2.611469281100988 0.0090154086930522 1.0 0.8982894305628181 6 P06280,P17900,P04062,P04066 4 +Retrograde transport endosome to golgi 0.5870352301613548 2.5697578302937987 0.0101769629652368 1.0 0.8982894305628181 37 O60499,O15498,Q4J6C6,Q8NBN3,O15260,O75503 6 +Inorganic anion transport 0.603657029730054 2.485657522385877 0.0129312343903744 1.0 0.8982894305628181 30 P21796,P30536,O43681,P45880,Q9Y277,Q9UBX3,Q9UHG3,P33527,Q9H0H5,Q15043,P08183 11 +Lysosomal lumen acidification 0.9465551508481342 2.468101687626516 0.0135831726983268 1.0 0.8982894305628181 5 P50897,Q8N511 2 +Vacuolar acidification 0.8695089536279283 2.442186167736262 0.0145986162297844 1.0 0.8982894305628181 10 O75503,P50897,Q9Y487,Q8N511 4 +Protein catabolic process in the vacuole 0.895558029987998 2.426716098646311 0.0152361734450587 1.0 0.8982894305628181 6 P04062,O14773,Q8N511 3 +Lysosomal protein catabolic process 0.895558029987998 2.426716098646311 0.0152361734450587 1.0 0.8982894305628181 6 P04062,O14773,Q8N511 3 +Glycoside catabolic process 0.9291653834308562 2.3994923197161437 0.016417824229516 1.0 0.8982894305628181 5 P06280,Q9BTY2,P04062,P04066 4 +Vitamin transmembrane transport 0.8886500245723522 2.3990137298723946 0.0164392982769252 1.0 0.8982894305628181 6 Q9H2D1,P04062,Q8WTV0 3 +Monovalent inorganic cation homeostasis 0.5903363807356314 2.3909416612296055 0.0168052229458748 1.0 0.8982894305628181 30 Q8N511,Q9Y487,Q15904,P50897,O75503,Q93050 6 +Regulation of lysosomal lumen ph 0.8748729170889593 2.369391599168726 0.0178173772346847 1.0 0.8982894305628181 7 O75503,P50897,Q8N511 3 +Cellular response to oxygen levels 0.5585176644170187 2.3689075097449006 0.0178407143152543 1.0 0.8982894305628181 36 P07237,Q8N511,P55786,O75306,Q15904,Q9Y487,Q9NQ88,P09601,Q96A26,Q15118,P27144,Q8IXJ6 12 +Liposaccharide metabolic process 0.8022708841786521 2.356390308458838 0.0184535168206718 1.0 0.8982894305628181 15 P06280,P16278,P04066,P17900,P04062,Q8NBX0 6 +Entry into host 0.5657799556283434 2.3463690117283496 0.0189573283386959 1.0 0.8982894305628181 31 P19474,P07237,P11279,O15118,Q14108,Q8WTV0,Q9BTY2,O14786 8 +Secondary alcohol metabolic process 0.5629734066483575 2.337511047311841 0.0194126271927905 1.0 0.8982894305628181 40 O75874,P34913,Q9BQE5,P61916,P04035,O15118,P16435,P05067,P48735,P14324,Q15392,P35610,P37268,Q14739,P04062,Q8WTV0,Q16850 17 +Aminoglycan catabolic process 0.9498152709359596 2.3318026017334414 0.0197110781087688 1.0 0.8982894305628181 4 P54802,P15586,P04066 3 +Glycosaminoglycan catabolic process 0.9498152709359596 2.3318026017334414 0.0197110781087688 1.0 0.8982894305628181 4 P54802,P15586,P04066 3 +Tetrapyrrole catabolic process 0.9344408060197088 2.2710080226010496 0.0231464922939834 1.0 0.8982894305628181 4 P30519,P09601 2 +Peptide catabolic process 0.8177934986103321 2.2536615618137983 0.0242174672609467 1.0 0.8982894305628181 11 P42892,P55786,P09960,Q9NZ08,O14773,Q9UIQ6 6 +Acute inflammatory response 0.8922344824489523 2.251996513904824 0.0243224923176921 1.0 0.8982894305628181 5 Q9BQE5 1 +Regulation of cellular ph 0.7079309443740347 2.2413297115480018 0.0250047257522669 1.0 0.8982894305628181 21 Q8N511,Q9Y487,Q15904,P50897,O75503,Q93050 6 +Regulation of ph 0.7079309443740347 2.2413297115480018 0.0250047257522669 1.0 0.8982894305628181 21 Q8N511,Q9Y487,Q15904,P50897,O75503,Q93050 6 +Vitamin transport 0.8261599608511244 2.2229445993973234 0.026219535900662 1.0 0.8982894305628181 9 Q9H2D1,P33527,P04062,Q8WTV0 4 +Sphingoid metabolic process 0.8842397866342775 2.219747718077184 0.0264358976928642 1.0 0.8982894305628181 5 Q06136,Q13510 2 +Ganglioside metabolic process 0.917186792628057 2.2023266658685525 0.0276422418886133 1.0 0.8982894305628181 4 P17900 1 +Cellular monovalent inorganic cation homeostasis 0.6292267906545157 2.1988073066956404 0.027891626741876 1.0 0.8982894305628181 26 Q8N511,Q9Y487,Q15904,P50897,O75503,Q93050 6 +Macromolecule depalmitoylation 0.8781087578132153 2.1949399821411495 0.0281679032884372 1.0 0.8982894305628181 5 P50897,Q9UMR5,Q9NUJ1 3 +Neuromuscular process controlling balance 0.8032587975821752 2.1889066859781967 0.0286036230265525 1.0 0.8982894305628181 11 P17900,P05067,O14773 3 +Antigen processing and presentation of endogenous peptide antigen 0.8312135147722866 2.1887242192172396 0.0286168905623591 1.0 0.8982894305628181 7 Q6P179,Q03518,P10321,P01889,Q9NZ08 5 +Antigen processing and presentation of endogenous antigen 0.8312135147722866 2.1887242192172396 0.0286168905623591 1.0 0.8982894305628181 7 Q6P179,Q03518,P10321,P01889,Q9NZ08 5 +Diol metabolic process 0.8299297365227535 2.1833539295232867 0.0290097559010882 1.0 0.8982894305628181 7 P04062,P35270,P00374,Q13510 4 +Diol biosynthetic process 0.8299297365227535 2.1833539295232867 0.0290097559010882 1.0 0.8982894305628181 7 P04062,P35270,P00374,Q13510 4 +Negative regulation of calcium ion transport 0.8299069090426195 2.183258407966996 0.0290167856267271 1.0 0.8982894305628181 7 P0DP25,P21796 2 +Negative regulation of calcium ion transmembrane transport 0.8299069090426195 2.183258407966996 0.0290167856267271 1.0 0.8982894305628181 7 P0DP25,P21796 2 +Regulation of nitric oxide synthase activity 0.8324602472106434 2.170212905128566 0.0299907208919194 1.0 0.8982894305628181 6 P06280,P0DP25,Q8WTV0 3 +Phospholipid transport 0.7610845574157976 2.159053597242813 0.0308460090435052 1.0 0.8982894305628181 15 Q00169,Q14108,P33527,Q8WTV0,P08183 5 +Response to testosterone 0.8073037552205363 2.141438472312052 0.0322386952342688 1.0 0.8982894305628181 9 P30536,P49321,P04062 3 +Ph reduction 0.7747890810106174 2.1355558012103875 0.0327156372886825 1.0 0.8982894305628181 13 O75503,P50897,Q9Y487,Q8N511 4 +Sterol metabolic process 0.5273075850980787 2.1253487026959648 0.0335575272348829 1.0 0.8982894305628181 36 P34913,Q9BQE5,P61916,P04035,O15118,P16435,P05067,P14324,Q15392,P35610,P37268,Q14739,P04062,Q8WTV0,Q16850 15 +Inflammatory cell apoptotic process 0.8608988338138734 2.1249512079070314 0.0335906844163491 1.0 0.8982894305628181 5 O75844 1 +Hormone metabolic process 0.5186556477961948 2.124120262449008 0.0336600885800895 1.0 0.8982894305628181 32 P30536,P42892,Q9HB40,Q8TAD4,O75844,O95470 6 +Modified amino acid transport 0.8192706220882906 2.115610927591385 0.0343779116918423 1.0 0.8982894305628181 6 Q9H2D1,P33527,O43772 3 +Locomotory behavior 0.5349590648751391 2.1136727530030353 0.0345432272315693 1.0 0.8982894305628181 31 P54802,P04080,O15118,P05067,P50897,O75844,P10253,Q8N2K0 8 +Aminoglycan metabolic process 0.7306804833742384 2.1099619948769943 0.0348616295716006 1.0 0.8982894305628181 17 P54802,P15586,P16278,P06865,P04066,Q8N6G5 6 +Sterol homeostasis 0.785430426702799 2.108833902579938 0.0349589211302545 1.0 0.8982894305628181 11 P34913,P61916,O15118,Q9H4M9,P35610,Q8WTV0,Q5BJF2 7 +Response to hepatocyte growth factor 0.8564405794893326 2.1067362004005297 0.0351404524485281 1.0 0.8982894305628181 5 Q06481,P46108,Q8IXJ6 3 +Positive regulation of pinocytosis 0.8920195644277861 2.1012970213593007 0.0356149010729676 1.0 0.8982894305628181 4 P50897 1 +Regulation of pinocytosis 0.8920195644277861 2.1012970213593007 0.0356149010729676 1.0 0.8982894305628181 4 P50897 1 +Negative regulation of leukocyte mediated immunity 0.8524792115799111 2.0905224109885188 0.0365708973737819 1.0 0.8982894305628181 5 P09601,Q96FV9,P46108,P01889 4 +Carbohydrate derivative catabolic process 0.5206144518067146 2.089063575029733 0.0367020006888914 1.0 0.8982894305628181 35 P06280,P15586,P54802,O00462,P16278,P04066,P06865,P17900,Q9BW91,P04062,Q9BTY2,Q9H773,Q13126 13 +Neuron projection arborization 0.812362498634202 2.0868780987474573 0.0368991551070181 1.0 0.8982894305628181 6 Q9HCE1,Q13641 2 +Regulation of natural killer cell mediated immunity 0.8097439284081605 2.0759626076422224 0.0378974094621189 1.0 0.8982894305628181 6 P11279,P04439,P46108,P01889 4 +Pinocytosis 0.795833711929849 2.039522532267526 0.0413979047683104 1.0 0.8982894305628181 7 P50570,P50897,Q06481,Q9H223 4 +Cellular response to increased oxygen levels 0.8004137356040044 2.0369624358649356 0.0416538064950589 1.0 0.8982894305628181 6 Q8N511,Q15904 2 +Prostate gland development 0.7993656176731065 2.0325708696679308 0.0420958970393063 1.0 0.8982894305628181 6 P07602,P04083 2 +Protein depalmitoylation 0.8745750216137216 2.0306909799625465 0.0422863519328635 1.0 0.8982894305628181 4 P50897,Q9NUJ1 2 +Amide transport 0.5253928321874823 2.0275833333618274 0.0426027914423949 1.0 0.8982894305628181 41 O43768,Q15907,Q6ZWJ1,Q03518,Q8NE86,Q8N183,O00400,P30626,P40939,Q9H2D1,P33527,P41440,P04083,P07602,P00367,P08183 16 +Negative regulation of gliogenesis 0.7980811071666353 2.027185963946096 0.0426433980489848 1.0 0.8982894305628181 6 P30536,Q8IXJ6 2 +Negative regulation of immune effector process 0.7803339678556338 2.023566305618462 0.0430147948415886 1.0 0.9031710332485514 9 P04439,P46108,P01889,Q96FV9,P09601,P04083 6 +Regulation of triglyceride metabolic process 0.8713044847273442 2.0174021382538747 0.0436535643162863 1.0 0.9080449024428504 4 Q8NCG7,Q8WTV0 2 +Glycolipid transport 0.8692775260771459 2.009158152306852 0.0445203641339735 1.0 0.914998982523792 4 P07602 1 +Negative regulation of nitric oxide metabolic process 0.8679510061321611 2.0037596493099947 0.0450958131495708 1.0 0.914998982523792 4 P06280,P30536 2 +Anion transmembrane transport 0.5364719336291136 2.0022419149345017 0.0452587197168028 1.0 0.914998982523792 48 P21796,Q8TB61,P45880,Q9Y277,Q9UBX3,Q86VD7,Q9H2D1,Q9UHG3,P33527,Q9Y619,P08183 11 +N terminal protein amino acid modification 0.7658834023586564 1.9884443719824203 0.0467625655191064 1.0 0.9191900036840764 10 Q9BV86,Q86UY6,P53582,Q14CX7 4 +Diacylglycerol metabolic process 0.8614953031536605 1.9774497966187956 0.0479908099379029 1.0 0.9230966513453104 4 Q9HCL2 1 +Regulation of leukocyte degranulation 0.8247932741334065 1.9764553552594903 0.0481032273857073 1.0 0.9230966513453104 5 Q15833,P09601 2 +Glial cell proliferation 0.7838098835410182 1.9671471995612335 0.0491662431263817 1.0 0.932428429027304 6 P30536,P04062 2 +Regulation of blood pressure 0.6914121921497616 1.9613266331903088 0.0498409323671682 1.0 0.9397122729401662 18 P42892,Q9HB40,P42785,Q9NZ08,P09601,Q9UIQ6 6 +Transition metal ion homeostasis 0.5915932196310497 1.9561483797659431 0.0504476773700075 1.0 0.9430666352521424 26 Q8N511,P30519,P05067,Q8TAD4,Q15904,P09601,P02792 7 +Regulation of phospholipase activity 0.7707789838104819 1.955483369816932 0.050526044363147 1.0 0.9430666352521424 8 P50897 1 +Regulation of glial cell proliferation 0.8559206700778553 1.9546814510753991 0.0506206807830251 1.0 0.9430666352521424 4 P30536 1 +Organic cation transport 0.7791340918453364 1.947392592954023 0.0514876854033135 1.0 0.9430666352521424 6 O43772,Q70HW3 2 +Positive regulation of viral life cycle 0.7791127541589778 1.9473023501335511 0.0514984971327456 1.0 0.9430666352521424 6 P19474,Q99816,P07237,P52292,Q9H9H4 5 +Vacuole organization 0.5445967167784221 1.9409836022555895 0.0522602663632021 1.0 0.9430666352521424 56 P54802,Q8N511,P11117,P50897,O75503,Q14108,P10253,O14773,Q9HC07,P04062 10 +Negative regulation of lymphocyte mediated immunity 0.8522167487684705 1.9395286828289144 0.0524369954086629 1.0 0.9430666352521424 4 Q96FV9,P46108,P01889 3 +Ceramide metabolic process 0.6967353931371044 1.9359401808439416 0.0528750278091356 1.0 0.9430666352521424 17 P06280,Q8NCC3,Q13510,P17900,P04062,O95470 6 +Amine biosynthetic process 0.8144650617412442 1.93357349708125 0.0531655884417521 1.0 0.9430666352521424 5 Q6QHF9 1 +Signaling receptor ligand precursor processing 0.8453001732378276 1.9111803676740884 0.0559814059163663 1.0 0.9430666352521424 4 P42892 1 +Leukocyte degranulation 0.7566712882080716 1.8938016507576545 0.0582513424722281 1.0 0.9430666352521424 8 Q15833,P09601 2 +Regulation of cell killing 0.7508504876980108 1.8929980570241547 0.0583581278546476 1.0 0.9430666352521424 9 Q9NUQ9,P04439,Q9BY67,P46108,P01889,P11279 6 +Antigen processing and presentation of exogenous peptide antigen 0.8040264882714024 1.8900566813829625 0.0587503797950645 1.0 0.9430666352521424 5 Q9UIQ6,P04439,Q03518 3 +Lipid translocation 0.8038506036759676 1.889321945571302 0.0588487026841293 1.0 0.9430666352521424 5 P33527 1 +Positive regulation of monooxygenase activity 0.7652715998514735 1.8885862147301875 0.0589472955883443 1.0 0.9430666352521424 6 P0DP25,P00374,Q8WTV0 3 +Oligosaccharide metabolic process 0.7602544606044154 1.8870082304464757 0.0591592186470739 1.0 0.9430666352521424 7 P06280,P17900,O00462 3 +Positive regulation of nitric oxide synthase activity 0.8347443822011176 1.8677869780976664 0.0617917692521989 1.0 0.9430666352521424 4 P0DP25,Q8WTV0 2 +Regulation of leukocyte mediated cytotoxicity 0.7502518952833165 1.8656073340292791 0.0620963227840063 1.0 0.9448868692803976 8 P04439,Q9BY67,P46108,P01889,P11279 5 +Sphingosine biosynthetic process 0.833951801918073 1.8645225983189384 0.0622483510944171 1.0 0.9449767289380184 4 Q13510 1 +Regulation of membrane lipid distribution 0.7546173578547262 1.8626232524031137 0.0625152905423873 1.0 0.946806519760232 7 Q96CP7,P33527 2 +Modulation of excitatory postsynaptic potential 0.8298777603427707 1.8477295309190367 0.0646414796791323 1.0 0.9494359808948324 4 Q9UQB8 1 +Negative regulation of exocytosis 0.7935287559960842 1.8461181175010273 0.0648750567461782 1.0 0.9494359808948324 5 P09601 1 +T cell differentiation involved in immune response 0.7935066704009595 1.8460254956882565 0.0648885035677486 1.0 0.9494359808948324 5 Q9UDY8 1 +Cd4 positive alpha beta t cell differentiation 0.7935066704009595 1.8460254956882565 0.0648885035677486 1.0 0.9494359808948324 5 Q9UDY8 1 +Cytokine production involved in inflammatory response 0.793280154489019 1.845075497349088 0.0650265569801391 1.0 0.9494359808948324 5 Q8IV08,Q06481 2 +Peptidyl proline modification 0.4828335227015764 1.8356159475158176 0.0664144768825358 1.0 0.9494359808948324 32 Q9BV86,O75718,P07237,P30414,Q15257,O15460,P13674,O43447,Q9Y237,Q9NWM8,Q9Y680,Q9Y3C6,Q32P28 13 +Regulation of monooxygenase activity 0.7371151175476153 1.8315791428759 0.067014146580117 1.0 0.9494359808948324 9 P06280,P0DP25,P00374,Q8WTV0 4 +Isocitrate metabolic process 0.7899446526976219 1.8310773606557007 0.0670889971175108 1.0 0.9494359808948324 5 P48735 1 +Regulation of biological process involved in symbiotic interaction 0.7367803856594566 1.830077789763733 0.0672383075674001 1.0 0.9494359808948324 9 P19474,P07237,Q9BTY2 3 +Intracellular lipid transport 0.730226218596426 1.8270303198426727 0.0676952107799997 1.0 0.9494359808948324 10 O43772,P23786,O15118 3 +N terminal protein amino acid acetylation 0.7503856846109125 1.8250473003366257 0.0679938917838076 1.0 0.9494359808948324 6 Q86UY6,Q14CX7,Q5VZE5,Q9BXJ9 4 +Negative regulation of smoothened signaling pathway 0.8230774607203908 1.8196495667438992 0.0688123881831663 1.0 0.9494359808948324 4 Q6PHR2,P06400 2 +Positive regulation of peptidyl threonine phosphorylation 0.7489773845891052 1.819015558228192 0.0689090564884757 1.0 0.9494359808948324 6 P05067,P0DP25,Q9Y376 3 +Leukocyte mediated cytotoxicity 0.6997215957250991 1.8160280115417575 0.069366075325117 1.0 0.9494359808948324 14 P04439,Q9BY67,P46108,P01889,P53634,Q15833,P51809,P11279 8 +Intermembrane lipid transfer 0.7436857320215888 1.8151680923994211 0.0694980815314609 1.0 0.9494359808948324 7 P30536,Q00169 2 +Lipoprotein localization 0.7857667781155682 1.8135199586887183 0.0697516631220334 1.0 0.9494359808948324 5 A6NIH7 1 +Ceramide transport 0.7856227907232858 1.8129143822042184 0.0698450276325521 1.0 0.9494359808948324 5 P07602 1 +Regulation of peptidyl threonine phosphorylation 0.7382132501457214 1.8125224397276671 0.0699055098701673 1.0 0.9494359808948324 8 P05067,Q8IXJ6,P0DP25,Q9Y376 4 +Regulation of viral entry into host cell 0.7847653702796773 1.809307627473452 0.0704032246778323 1.0 0.9494359808948324 5 P19474 1 +Regulation of mitophagy 0.7407386734948249 1.8023374405625951 0.0714923313060138 1.0 0.9494359808948324 7 Q709C8,Q9NQ88,P21796 3 +Response to zinc ion 0.7448693290722077 1.801400772836296 0.0716397344332606 1.0 0.9494359808948324 6 P30536,P09960 2 +Glycerophospholipid catabolic process 0.7385296137925617 1.7927095961851185 0.0730193713061733 1.0 0.9494359808948324 7 Q8NCC3,Q8WTV0 2 +Regulation of atp metabolic process 0.5658627882161157 1.78690495452073 0.0739528516092911 1.0 0.9494359808948324 26 P14406,Q9BSK2,Q9Y3D6,P00403,P30536,P05067,P27144 7 +Regulation of nervous system process 0.7202950061687012 1.781619153874366 0.0748113587786218 1.0 0.9494359808948324 10 Q9UQB8,P04062 2 +Negative regulation of glycoprotein metabolic process 0.8137146540667164 1.7808900778347962 0.0749304098682372 1.0 0.9494359808948324 4 Q9BXS4 1 +Positive regulation of cell killing 0.7357944197908857 1.780776615393555 0.074948951096593 1.0 0.9494359808948324 7 P11279,Q9BY67,P04439,P01889 4 +Alcohol biosynthetic process 0.4801046238441017 1.7793584754472058 0.0751810097116687 1.0 0.9494359808948324 34 O15269,P35270,P04035,P00374,Q13510,P16435,Q9NPH2,P14324,Q15392,P37268,Q14739,P29218,P04062,Q16850 14 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8131619743480989 1.7785986549715518 0.0753055847835058 1.0 0.9494359808948324 4 Q9UIQ6,Q03518 2 +Negative regulation of cation channel activity 0.7766009478973377 1.7749086644913088 0.0759129694115401 1.0 0.9494359808948324 5 P0DP25 1 +Lipoprotein catabolic process 0.77631362334598 1.773696287489218 0.0761134008663164 1.0 0.9494359808948324 5 P50897,Q9NUJ1 2 +Regulation of oxidative phosphorylation 0.7283740846953641 1.7689366416760115 0.0769044485048564 1.0 0.9494359808948324 8 P14406 1 +Positive regulation of protein neddylation 0.8102431405434726 1.766490796742742 0.0773135442394765 1.0 0.9494359808948324 4 Q8IWE4,Q92564 2 +Substrate dependent cell migration cell extension 0.8099952875013696 1.7654621713090293 0.0774861225192391 1.0 0.9494359808948324 4 O00560 1 +Regulation of synapse structure or activity 0.4804581474754328 1.7653778292212872 0.0775002869757091 1.0 0.9494359808948324 35 P05067,Q15375,P50897,Q9UQB8,Q13641,Q16539 6 +Mucopolysaccharide metabolic process 0.7165540636353311 1.7644640374949885 0.0776538849212675 1.0 0.9494359808948324 10 P15586,P16278,Q8NCH0,Q8N6G5,O43505 5 +Determination of adult lifespan 0.7269591431134435 1.7626542257017677 0.0779588254187104 1.0 0.9494359808948324 8 O75844 1 +Negative regulation of ryanodine sensitive calcium release channel activity 0.8084919771515686 1.7592216031311512 0.0785398763157179 1.0 0.9494359808948324 4 P0DP25 1 +Positive regulation of sequestering of calcium ion 0.8084919771515686 1.7592216031311512 0.0785398763157179 1.0 0.9494359808948324 4 P0DP25 1 +Negative regulation of calcium ion transport into cytosol 0.8084919771515686 1.7592216031311512 0.0785398763157179 1.0 0.9494359808948324 4 P0DP25 1 +Mast cell activation 0.7721039229209048 1.7559194820815205 0.0791021579053958 1.0 0.9494359808948324 5 P09601 1 +Mast cell activation involved in immune response 0.7721039229209048 1.7559194820815205 0.0791021579053958 1.0 0.9494359808948324 5 P09601 1 +Protein retention in er lumen 0.7713486407351096 1.7527273440885447 0.0796488197433697 1.0 0.9494359808948324 5 P24390 1 +Maintenance of protein localization in endoplasmic reticulum 0.7713486407351096 1.7527273440885447 0.0796488197433697 1.0 0.9494359808948324 5 P24390 1 +Endothelial cell migration 0.4716229157835421 1.7437394287142598 0.0812045367252634 1.0 0.9586398038650032 32 Q9Y6N7,Q4VCS5,P42785,P57105,P09601,Q8WTV0,Q16539,O14786,P04083 9 +T cell mediated cytotoxicity 0.727131953768634 1.7428974511775444 0.0813515293555566 1.0 0.9586398038650032 7 Q9BY67,P04439,P01889,P53634 4 +Modification of postsynaptic structure 0.7307078790657281 1.740453850071097 0.0817793569128408 1.0 0.9586398038650032 6 Q9UQB8,P07737,O95793 3 +Macrophage differentiation 0.7304816018622344 1.7394772394079336 0.0819508523652545 1.0 0.9586398038650032 6 P05067,P04062 2 +Sulfur compound transport 0.6972862458104805 1.733224462236131 0.0830557807290364 1.0 0.9586398038650032 12 Q70HW3,O00400,Q9UBX3,P33527,Q8TB61 5 +Glycoside metabolic process 0.714410706769828 1.7292659853001349 0.0837615014339108 1.0 0.9586398038650032 9 P06280,Q9BTY2,P04062,P04066 4 +Manganese ion transport 0.8012829136273395 1.7292572456780957 0.0837630648961149 1.0 0.9586398038650032 4 Q9HD20,Q9HC07 2 +Manganese ion transmembrane transport 0.8012829136273395 1.7292572456780957 0.0837630648961149 1.0 0.9586398038650032 4 Q9HD20,Q9HC07 2 +Mitotic nuclear membrane organization 0.727918726845912 1.7284098991120975 0.0839147619895366 1.0 0.9586398038650032 6 Q86XL3 1 +Lipopolysaccharide mediated signaling pathway 0.7237617281905782 1.7281249674419692 0.0839658221161343 1.0 0.9586398038650032 7 Q9UDY8,Q8WTV0 2 +Cholesterol efflux 0.7235027907433641 1.7269891795868952 0.0841696067800796 1.0 0.9586398038650032 7 P61916,O15118,Q8WTV0 3 +Response to estrogen 0.6959457959607883 1.7268320176837129 0.0841978364922408 1.0 0.9586398038650032 12 P09601 1 +Natural killer cell mediated immunity 0.7122978305122232 1.7196964690600325 0.0854876300070994 1.0 0.9686738133894222 9 P04439,Q9BY67,P46108,P01889,P11279 5 +Autophagy of mitochondrion 0.4685620371962014 1.7185293276552247 0.0857001098175351 1.0 0.9686738133894222 32 Q9Y3D6,Q16543,P21796,P30536,P52789,Q9NQ88,Q709C8,P04062,Q9BWH2 9 +Antigen processing and presentation of peptide antigen 0.6872300501750653 1.71807784309471 0.0857824176468424 1.0 0.9686738133894222 13 P04439,Q6P179,P10321,Q03518,P01889,Q9NZ08,Q9UIQ6 7 +Carbohydrate derivative transport 0.6039716199970361 1.7158044773519063 0.0861978344293299 1.0 0.969463296094742 22 P61916,Q86VD7,P41440,Q8WTV0,P07602,Q8TB61 6 +Antigen processing and presentation of peptide antigen via mhc class i 0.6926774667044588 1.7112309840900974 0.0870384810731927 1.0 0.9733433267686232 12 Q6P179,P10321,Q03518,P01889,Q9NZ08,Q9UIQ6 6 +Positive regulation of actin cytoskeleton reorganization 0.7591866760702074 1.7012146105810917 0.0889026952745113 1.0 0.9840359998946208 5 Q9UQB8 1 +Positive regulation of chemokine production 0.7131123257680337 1.7009864241492567 0.088945536469726 1.0 0.9840359998946208 8 P09601 1 +Cellular response to amyloid beta 0.7187314695849446 1.6886470370283106 0.0912870909160918 1.0 0.9840359998946208 6 P05067 1 +Response to amyloid beta 0.7187314695849446 1.6886470370283106 0.0912870909160918 1.0 0.9840359998946208 6 P05067 1 +Regulation of golgi organization 0.7914875807245713 1.6884458146320385 0.091325682139582 1.0 0.9840359998946208 4 Q9P2W9,Q13190 2 +Regulation of lipase activity 0.7053340940489832 1.6881005982401214 0.0913919196476826 1.0 0.9840359998946208 9 P50897 1 +Neutral lipid biosynthetic process 0.7095342519192636 1.6849971698574706 0.0919891175347922 1.0 0.9840359998946208 8 Q9HCL2,Q8WTV0 2 +Negative regulation of blood pressure 0.7901977500962697 1.683063796999764 0.0923627419106285 1.0 0.9840359998946208 4 Q9HB40 1 +Maintenance of protein location 0.4631096315375748 1.6734937122787534 0.0942301433293073 1.0 0.989263533945829 32 P30536,P24390,Q9UH99,Q7L5D6,P30626,O43731,P52789,Q709C8 8 +Protein transmembrane transport 0.5199556578830387 1.6583506897710172 0.0972467032552089 1.0 0.9919731489663104 28 Q99595,Q9NS69,Q15629 3 +Lens development in camera type eye 0.707209905556007 1.655297587036903 0.0978641481681519 1.0 0.9919731489663104 7 Q14517 1 +Positive regulation of necrotic cell death 0.710464782930297 1.6527520938187978 0.0983813275280343 1.0 0.9919731489663104 6 P30536 1 +Fat soluble vitamin metabolic process 0.7470011593262718 1.6494001718506448 0.099065679551431 1.0 0.9919731489663104 5 Q8N0U8 1 +Negative regulation of cell killing 0.781711822660095 1.647610295358791 0.0994326664033229 1.0 0.9919731489663104 4 P04439,P46108,P01889 3 +Cellular extravasation 0.7092655957704752 1.6475361570732854 0.0994478906898754 1.0 0.9919731489663104 6 Q9Y624,P46108,P46109 3 +Positive regulation of atp metabolic process 0.7090871093004983 1.6467596288948336 0.0996074624185512 1.0 0.9919731489663104 6 P05067 1 +Positive regulation of nucleotide metabolic process 0.7090871093004983 1.6467596288948336 0.0996074624185512 1.0 0.9919731489663104 6 P05067 1 +Positive regulation of jnk cascade 0.6993806451473239 1.6395074111084624 0.1011076284864751 1.0 0.9919731489663104 8 O00560 1 +Antigen processing and presentation 0.5895554768095007 1.6297444092268216 0.10315552725711 1.0 0.9919731489663104 22 P04439,Q6P179,Q03518,P10321,P01889,Q9NZ08,P04062,Q9UIQ6 8 +Carbohydrate catabolic process 0.4856313880423554 1.6266607517132308 0.1038091688354267 1.0 0.9919731489663104 46 P16278,P17900,P05067,Q9NUJ1,Q9BRR6,Q14108,P10253,O00462 8 +Organic acid transmembrane transport 0.4585835581889004 1.6189814958824131 0.1054512445262294 1.0 0.9919731489663104 33 O43772,Q9UBX3,P23786,Q9H2D1,P33527,Q9Y619,P08183 7 +Myeloid cell activation involved in immune response 0.6977481227123692 1.6134674818560126 0.1066429825275174 1.0 0.9919731489663104 7 P09601 1 +Natural killer cell activation 0.6970291456865148 1.6102832509641607 0.1073360340093056 1.0 0.9919731489663104 7 P11279,P46379,P51809 3 +Membrane lipid biosynthetic process 0.5960931365319223 1.6055766666305027 0.1083669556355304 1.0 0.9919731489663104 21 Q06136,Q8NBX0,P04062,Q13510 4 +Glyoxylate metabolic process 0.9496598398812792 1.59813983199794 0.1100118606428299 1.0 0.9919731489663104 3 P48735 1 +Positive regulation of triglyceride metabolic process 0.9488842121450732 1.5951852100871262 0.1106708250881347 1.0 0.9919731489663104 3 Q8WTV0 1 +Extracellular exosome assembly 0.7690697045298203 1.5946569302475144 0.1107889742840337 1.0 0.9919731489663104 4 O00560 1 +Regulation of syncytium formation by plasma membrane fusion 0.7332629765474209 1.590757586822269 0.1116641414200168 1.0 0.9919731489663104 5 Q16539,Q9H4M9,P41440 3 +Positive regulation of myoblast fusion 0.7332629765474209 1.590757586822269 0.1116641414200168 1.0 0.9919731489663104 5 Q16539,Q9H4M9,P41440 3 +Regulation of myoblast fusion 0.7332629765474209 1.590757586822269 0.1116641414200168 1.0 0.9919731489663104 5 Q16539,Q9H4M9,P41440 3 +Positive regulation of syncytium formation by plasma membrane fusion 0.7332629765474209 1.590757586822269 0.1116641414200168 1.0 0.9919731489663104 5 Q16539,Q9H4M9,P41440 3 +T cell migration 0.6838948536567379 1.5903083021819682 0.1117653281646204 1.0 0.9919731489663104 9 P05067,P46108,P46109 3 +Cellular response to biotic stimulus 0.4588340927191646 1.587274564672336 0.1124504733479756 1.0 0.9919731489663104 35 Q9NUQ9,P11802,P30536,O75844,Q9NQ88,O43823,Q04721,Q8WTV0,Q16539,Q9UDY8,P14174,Q8IXJ6 12 +Regulation of t cell migration 0.7317758437653908 1.5843961078859337 0.1131036070801507 1.0 0.9919731489663104 5 P05067,P46108 2 +Oligosaccharide catabolic process 0.9459948396402718 1.584176468147821 0.113153566735128 1.0 0.9919731489663104 3 P17900 1 +Positive regulation of protein dephosphorylation 0.6596331082067279 1.583123316759261 0.1133933600817602 1.0 0.9919731489663104 13 Q86XL3,P04062 2 +Detection of biotic stimulus 0.6940948979558653 1.5813625362120929 0.1137951683317706 1.0 0.9919731489663104 6 P30536,P01889,Q8WTV0 3 +Negative regulation of protein maturation 0.7310186305638171 1.5811560161120135 0.1138423693726748 1.0 0.9919731489663104 5 Q9BXS4 1 +Pyridine containing compound metabolic process 0.6764610514817972 1.5790101326848065 0.114333732919114 1.0 0.9919731489663104 10 P43490 1 +Glutamate receptor signaling pathway 0.9445983379501388 1.5788544988788376 0.1143694347106323 1.0 0.9919731489663104 3 Q8NCG7,P05067 2 +Stress activated protein kinase signaling cascade 0.4554531541646099 1.5760597047198863 0.1150120443289903 1.0 0.9919731489663104 34 P49327,O15344,P05067,Q969S3,O75844,O00560,P78318,P46109,Q16539 9 +Nucleotide transmembrane transport 0.663342378033599 1.5703096306113058 0.1163430947531733 1.0 0.9965440977069832 12 Q9BSK2,Q9H2D1,Q8TB61,Q86VD7 4 +Tail anchored membrane protein insertion into er membrane 0.6783236313981267 1.5647748386648592 0.1176357134462802 1.0 1.0 9 O43681,P46379,Q7L5D6 3 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4793416010669807 1.5646193234279762 0.1176721952600778 1.0 1.0 30 Q9P2W9,Q9Y282,P24390,O43731,Q969X5 5 +Lipoprotein metabolic process 0.5983930556070832 1.560932139129531 0.1185397632247746 1.0 1.0 20 Q9BQE5,Q9NUJ1,P50897,P04062,Q8N2K0 5 +Outer mitochondrial membrane organization 0.7260360377542983 1.5598195586862518 0.1188025281064792 1.0 1.0 5 P07900,Q9NS69,O14737 3 +Embryonic heart tube development 0.6851018370520446 1.5573470183995943 0.1193881178423814 1.0 1.0 7 P42892,Q9Y366 2 +Positive regulation of cell cell adhesion mediated by cadherin 0.7600118195661184 1.5566255956775563 0.1195594031725131 1.0 1.0 4 P41440 1 +Regulation of cell cell adhesion mediated by cadherin 0.7600118195661184 1.5566255956775563 0.1195594031725131 1.0 1.0 4 P41440 1 +Regulation of cyclic nucleotide phosphodiesterase activity 0.7592364532019665 1.5533668072352294 0.1203355280589484 1.0 1.0 4 Q15043,P63244,P0DP25 3 +Triglyceride biosynthetic process 0.6870052746065003 1.5503237109727843 0.1210638390336753 1.0 1.0 6 Q8WTV0 1 +Intracellular sterol transport 0.6869184515595782 1.5499431628120346 0.1211551585533003 1.0 1.0 6 O15118 1 +Lymphocyte migration 0.6648241384091458 1.5495435685919376 0.1212511065160066 1.0 1.0 11 P05067,P46108,P04062,P46109 4 +Regulation of glucose import 0.6827724392037083 1.5469846496117057 0.1218669472169455 1.0 1.0 7 P52789,Q06481 2 +Adult locomotory behavior 0.6216828067247037 1.5408695217546005 0.1233485449547737 1.0 1.0 17 P04080,O15118,P05067,P50897,O75844 5 +Cellular transition metal ion homeostasis 0.5746274610175865 1.54003463627395 0.1235519108812674 1.0 1.0 22 Q8N511,P05067,Q8TAD4,Q15904,P09601,P02792 6 +Sensory perception of light stimulus 0.6207184656970689 1.5357116997168554 0.124609104322426 1.0 1.0 17 Q99797,Q00169,P50897,Q9H6K4,Q9H0F7 5 +Proteoglycan biosynthetic process 0.6753427371343785 1.531167643946041 0.1257279652639984 1.0 1.0 8 Q93063,Q8WVQ1,O94766,Q8NCH0,Q8N6G5 5 +Amyloid precursor protein biosynthetic process 0.7533308592697006 1.5285303816107545 0.1263809062155294 1.0 1.0 4 Q9NQX7,Q92542 2 +Ganglioside catabolic process 0.9305229572544912 1.5251766485763978 0.127215043322753 1.0 1.0 3 P17900 1 +Fucose metabolic process 0.9304499810569458 1.5248981917035855 0.1272844929899597 1.0 1.0 3 Q9BTY2 1 +Negative regulation of establishment of protein localization to mitochondrion 0.7524671585382113 1.5248957604192517 0.1272850995041849 1.0 1.0 4 O95817,O95429 2 +Polyol biosynthetic process 0.6528702681332489 1.519642312169858 0.1286008975008634 1.0 1.0 12 O15269,P35270,P00374,Q13510,P29218,P04062 6 +Negative regulation of fat cell differentiation 0.7511427456184954 1.5193212941694652 0.1286816422856589 1.0 1.0 4 Q8N4Q0 1 +Proteoglycan metabolic process 0.6682469697924526 1.5184748571881292 0.1288947331689613 1.0 1.0 9 Q93063,Q8WVQ1,O94766,Q8NCH0,Q8N6G5 5 +Early endosome to golgi transport 0.6707243704246751 1.510256217263733 0.1309780589148945 1.0 1.0 8 O60499,O15260 2 +Regulation of protein dephosphorylation 0.512152977538894 1.510027312306778 0.1310364551521703 1.0 1.0 27 O43768,Q15257,P08238,Q12972,Q86XL3,P0DP25,P04062 7 +Diacylglycerol biosynthetic process 0.9260175758126256 1.5079829263321325 0.1315588968587104 1.0 1.0 3 Q9HCL2 1 +Protein localization to membrane raft 0.7481813413540791 1.5068521164314896 0.1318485674265981 1.0 1.0 4 O75955,P41440 2 +Regulation of endothelial cell migration 0.5351899455080003 1.5014330615009697 0.1332435879974298 1.0 1.0 25 P42785,P09601,P57105,Q8WTV0,Q16539,P04083 6 +Negative regulation of autophagy 0.5333187700796993 1.4891315338887725 0.1364527354657871 1.0 1.0 25 P30536,P10619,P09601,O15118 4 +Collagen fibril organization 0.6616727286188178 1.4881904170625977 0.1367006837579918 1.0 1.0 9 O60568,O75718,P06400,Q96AY3,P13674,P21359 6 +Lipid homeostasis 0.4957697215590562 1.4844444686984546 0.1376910449157733 1.0 1.0 28 P61916,O15118,O15260,Q9H4M9,Q96CP7,Q8WTV0,Q9HCL2,Q9BWH2 8 +Regulation of actin cytoskeleton reorganization 0.6508606432841352 1.4830559813050874 0.1380595378754763 1.0 1.0 11 P52565,O14786,Q9UQB8,Q9Y624 4 +Inorganic anion transmembrane transport 0.649223466191636 1.4752420521157226 0.140147479468915 1.0 1.0 11 P51790,Q9UHG3,Q9UBX3,P51797 4 +Dna replication synthesis of rna primer 0.7397360829242636 1.4712602978864275 0.1412207358691961 1.0 1.0 4 Q14181 1 +Triglyceride metabolic process 0.6425156394282961 1.4693772139329426 0.1417305041696508 1.0 1.0 12 Q8NCG7,Q9UBV2,Q9HCL2,Q8WTV0 4 +Urogenital system development 0.4625077083315999 1.4692926317013668 0.141753434495466 1.0 1.0 44 Q10567,O14786,Q15375,P42224,O75844,Q05086,P35610,P46379,P46109,P07602,P04083,O95470 12 +Modification of postsynaptic actin cytoskeleton 0.7391733222079936 1.4688870009268038 0.1418634410042345 1.0 1.0 4 Q9UQB8 1 +Establishment of pigment granule localization 0.73894779901155 1.4679358631289368 0.1421216454183516 1.0 1.0 4 Q15907,Q9H0F7 2 +Negative regulation of protein secretion 0.6572292315662425 1.4676887671343597 0.1421887833414516 1.0 1.0 9 Q16850,Q8N183,P04035,P40939 4 +Sphingolipid biosynthetic process 0.6293366624908997 1.4650163257312807 0.1429164636471274 1.0 1.0 14 Q06136,P04062,Q13510 3 +Positive regulation of phosphoprotein phosphatase activity 0.7377990149718678 1.4630904398423394 0.1434426334675529 1.0 1.0 4 Q15257,P0DP25 2 +Vesicle docking 0.6147714834212632 1.462494516672924 0.1436057458612993 1.0 1.0 16 O60499,O15498,Q13190,Q7Z6M1 4 +Regulation of sprouting angiogenesis 0.736123652792929 1.4560226341635858 0.1453863627116287 1.0 1.0 4 P57105 1 +Collateral sprouting 0.7360793690799875 1.455835794492888 0.1454380181035504 1.0 1.0 4 P05067 1 +Negative regulation of erk1 and erk2 cascade 0.6397096678770462 1.4557295124320635 0.1454674080774407 1.0 1.0 12 P57105 1 +Neuron apoptotic process 0.4685909237313775 1.455272757934336 0.1455937652907704 1.0 1.0 48 Q01105,P05067,P49427,P50897,Q15375,P09601,Q92542,P04062,Q96A26 9 +Mitochondrial respiratory chain complex assembly 0.4523448738749495 1.4503188088304078 0.1469696363748232 1.0 1.0 40 Q9BSK2,Q69YU5,O43676,Q6DKK2,Q9Y6M9,O95168,Q9H061,O75306 8 +Modification of synaptic structure 0.6574468529254984 1.4499820155281025 0.1470635344548962 1.0 1.0 8 P35080,Q9UQB8,P07737,O95793 4 +Positive regulation of autophagy 0.4357172373503796 1.4449460568826895 0.1484730381327568 1.0 1.0 32 P19474,P21796,Q9BXS4,P09601,Q13137 5 +Regulation of glucose transmembrane transport 0.6469791562580339 1.4409906390674203 0.14958732738988 1.0 1.0 10 Q16539,P52789,Q06481 3 +Positive regulation of interleukin 1 beta production 0.6982212069932083 1.4402497343183371 0.1497967569562419 1.0 1.0 5 P05067 1 +Nucleotide transport 0.5944684745633411 1.4380896134117418 0.1504086292894748 1.0 1.0 18 Q9BSK2,Q86VD7,Q9H2D1,P41440,Q8TB61 5 +Transepithelial transport 0.6589131684112086 1.4266971148895824 0.1536672176215869 1.0 1.0 6 P33527 1 +Positive regulation of smooth muscle cell migration 0.6947847697029943 1.4254303061679283 0.1540328528024381 1.0 1.0 5 O14786,P46108 2 +Chloride transmembrane transport 0.6516984803743643 1.4238207611016909 0.1544983642337336 1.0 1.0 8 Q9UHG3,P51797 2 +Intraciliary transport 0.6514810642162951 1.422830555160901 0.1547852814322476 1.0 1.0 8 O43805,Q96EX3 2 +Negative regulation of protein catabolic process 0.4549146307721469 1.4227024996824955 0.1548224156905286 1.0 1.0 43 P10619,O00560,P46379,Q16850,Q92530,Q8IXJ6 6 +Negative regulation of map kinase activity 0.6549541970223934 1.422690201220475 0.1548259824248106 1.0 1.0 7 P04062 1 +Pigment granule localization 0.6577466276744539 1.421543707835904 0.1551587564708836 1.0 1.0 6 Q15907,Q9H0F7 2 +Polyamine metabolic process 0.9012003693444144 1.4132198859563234 0.1575910812298651 1.0 1.0 3 Q6QHF9,P19623 2 +Spermidine metabolic process 0.9012003693444144 1.4132198859563234 0.1575910812298651 1.0 1.0 3 Q6QHF9,P19623 2 +Regulation of entry of bacterium into host cell 0.7259264365346514 1.4129730128965832 0.1576636592511258 1.0 1.0 4 Q9BTY2 1 +Apoptotic cell clearance 0.6453784603472505 1.412892191271829 0.1576874254401508 1.0 1.0 9 Q8WTV0 1 +Regulation of neurotransmitter levels 0.4728273600053325 1.4111263221438295 0.1582073698896187 1.0 1.0 29 Q4J6C6,Q8NCG7,O75955,P50897,Q15833,P0DP25,P41440 7 +Folic acid metabolic process 0.6523702168159192 1.4110987482907371 0.1582154990474129 1.0 1.0 7 Q9H2D1,P41440 2 +Negative chemotaxis 0.7253694581280743 1.4106202565203838 0.1583566154924591 1.0 1.0 4 Q9Y6N7,O94813,Q15375 3 +Antigen processing and presentation of exogenous antigen 0.648367905656748 1.4086462917249216 0.1589397834341841 1.0 1.0 8 Q9UIQ6,P04439,Q03518 3 +Regulation of phospholipase a2 activity 0.8991998168109655 1.4055798368372172 0.1598489268519896 1.0 1.0 3 P50897 1 +Regulation of t cell mediated cytotoxicity 0.7240163847996667 1.404904168923855 0.1600497767444699 1.0 1.0 4 P04439,P01889 2 +Positive regulation of t cell mediated cytotoxicity 0.7240163847996667 1.404904168923855 0.1600497767444699 1.0 1.0 4 P04439,P01889 2 +Vesicle docking involved in exocytosis 0.6436283783301616 1.404786365798686 0.1600848145744942 1.0 1.0 9 O15498,Q7Z6M1 2 +Adult behavior 0.541904298329937 1.4032969024436472 0.160528321515271 1.0 1.0 23 O15118,P05067,P50897,O75844,Q92542 5 +Microtubule anchoring at microtubule organizing center 0.6524953789279184 1.3983282644182728 0.1620145139756359 1.0 1.0 6 Q9Y496,Q14203,Q15154,Q8TD16,Q86VS8 5 +Protein targeting to mitochondrion 0.4539136396232079 1.398249288815063 0.1620382203004147 1.0 1.0 44 Q9Y3D6,O95429,Q10713,P30536,Q99797,P55786,Q9NS69,O14925,Q9P0J0,Q99595,Q8N4H5,Q9Y584,O14737 13 +Positive regulation of dephosphorylation 0.6095619854724521 1.398138586042437 0.1620714546640611 1.0 1.0 15 Q86XL3,P04062 2 +Cobalamin metabolic process 0.7219827586206845 1.3963117714723985 0.1626206305342759 1.0 1.0 4 Q96EY8,P33527,Q99707 3 +Glutathione metabolic process 0.5695282862049049 1.3948777855685066 0.1630526970408616 1.0 1.0 20 O15217 1 +Regulation of steroid biosynthetic process 0.6413017876597541 1.3940052673057122 0.1633160140534646 1.0 1.0 9 P30536,Q9UHI6,Q13510 3 +Cognition 0.4415589985932256 1.3934146800420333 0.1634944290574587 1.0 1.0 38 P04035,P17900,P05067,Q9UQN3,P50897,Q92542,Q13641 7 +Regulation of steroid metabolic process 0.6267498148729049 1.3925620463522748 0.1637522667797171 1.0 1.0 12 P30536,P34913,Q9UHI6,Q13510 4 +2 oxoglutarate metabolic process 0.6363422962702266 1.3909153702046697 0.1642510913724089 1.0 1.0 10 O75874,P48735 2 +Semi lunar valve development 0.6505137820504712 1.3895607543965425 0.1646623001007432 1.0 1.0 6 Q9Y6N7,P06400,Q04721 3 +Regulation of postsynaptic membrane potential 0.6402778608480522 1.3892587447688207 0.1647540840852333 1.0 1.0 9 Q9UQB8 1 +Chemical synaptic transmission postsynaptic 0.6402778608480522 1.3892587447688207 0.1647540840852333 1.0 1.0 9 Q9UQB8 1 +Lipid localization 0.5158890260730813 1.3886003727971827 0.1649543039491947 1.0 1.0 78 O15118,P30536,P33527,P07602,O43772,P08183,P35790,Q9BQE5,Q8WTV0,P61916,Q9H6V9,P17900,Q00169,Q9H4M9,Q14108,P04062,P04083,O15260,P23786 19 +Cellular modified amino acid catabolic process 0.6438115864928128 1.387868417196361 0.1651771165711235 1.0 1.0 8 Q8NBM8,Q9UHG3 2 +Regulation of necrotic cell death 0.6254798427082588 1.3863611445016566 0.1656366548121637 1.0 1.0 12 P30536,Q13510 2 +Iron ion homeostasis 0.5766110564105091 1.3853532886821185 0.1659444667411076 1.0 1.0 19 Q8N511,P30519,Q15904,P09601,P02792 5 +Peptidyl methionine modification 0.6853553955101896 1.3847241756284645 0.166136823832145 1.0 1.0 5 P53582,Q14CX7 2 +Golgi disassembly 0.6851149215990735 1.3836853188221554 0.1664548308528637 1.0 1.0 5 Q92538,Q13190 2 +Maintenance of protein localization in organelle 0.5843703636187138 1.3824447142167648 0.1668351947470192 1.0 1.0 18 Q9UH99,P24390,P30536,O43731 4 +Leukotriene metabolic process 0.7178528429069619 1.3788578861056302 0.1679385749769202 1.0 1.0 4 P09960 1 +Regulation of protein neddylation 0.6474798147195837 1.3761300091933155 0.1687813862314233 1.0 1.0 6 Q8IWE4,Q92564 2 +Intestinal absorption 0.6445372965120422 1.375920186749885 0.1688463446778338 1.0 1.0 7 Q14651,Q8WTV0 2 +Negative regulation of peptidyl threonine phosphorylation 0.890716640926644 1.373187001864871 0.1696942194623565 1.0 1.0 3 P0DP25 1 +Xenobiotic metabolic process 0.6171108709549928 1.372674772866307 0.1698534751221549 1.0 1.0 13 O15217 1 +Xenobiotic transport 0.6818479038888162 1.3695683760768411 0.1708216769448562 1.0 1.0 5 P33527,P08183 2 +Response to dietary excess 0.7155172413793056 1.3689849058977357 0.1710039931815443 1.0 1.0 4 Q16539,Q6KCM7,Q06481 3 +Toll like receptor 4 signaling pathway 0.8895044629116658 1.3685591510321595 0.1711371202359797 1.0 1.0 3 Q06481,P41440 2 +Regulation of toll like receptor 4 signaling pathway 0.8895044629116658 1.3685591510321595 0.1711371202359797 1.0 1.0 3 Q06481,P41440 2 +Presynapse organization 0.6815965753416298 1.3684821272133498 0.171161212697388 1.0 1.0 5 O00560 1 +Respiratory chain complex iii assembly 0.6446565396853307 1.3636246034347796 0.1726857445756902 1.0 1.0 6 Q9BSK2,Q69YU5 2 +Sulfur compound catabolic process 0.6331853696746463 1.3563523554684147 0.1749870847607311 1.0 1.0 9 P15586,P16278 2 +Regulation of leukocyte mediated immunity 0.4389618273970865 1.3552970463664271 0.1753229356794148 1.0 1.0 31 P04439,Q9BY67,P46108,P01889,Q15833,Q96FV9,P09601,P51809,P11279,Q9UDY8,Q9NQT5 11 +Negative regulation of establishment of protein localization 0.5014672182149972 1.3530461121501836 0.17604089944828 1.0 1.0 26 Q13438,P31150,P04035,O95429,Q8N183,Q16836,O95817,P40939,P21359,Q16850,P49257 11 +Tricarboxylic acid metabolic process 0.6316116875336205 1.3490447265754222 0.1773226003562842 1.0 1.0 9 O75874,P48735 2 +Regulation of endocytic recycling 0.7092067386131704 1.3423030894907844 0.1794977421084125 1.0 1.0 4 Q9H4M9 1 +Sensory perception 0.4272115588555594 1.3396054507215602 0.1803736507994822 1.0 1.0 34 Q99797,Q00169,P50897,Q14108,Q9H6K4,Q9H0F7 6 +Associative learning 0.5980704980932884 1.33863956625044 0.1806880389478364 1.0 1.0 15 P50897,P05067,Q13641 3 +Organelle inheritance 0.6361409298772207 1.3381491532309018 0.1808478203839809 1.0 1.0 7 Q92538,Q13190 2 +Regulation of dephosphorylation 0.4289844281278513 1.3378065382542077 0.1809595099837477 1.0 1.0 35 O43768,O95429,Q15257,P08238,Q12972,Q86XL3,P0DP25,P78318,P04062 9 +Negative regulation of glial cell proliferation 0.8811346601870693 1.3366136099330046 0.181348794172969 1.0 1.0 3 P30536 1 +Low density lipoprotein particle clearance 0.6198312881462886 1.3343983259736676 0.1820733483844114 1.0 1.0 11 Q92945,Q9H4M9,P09601,Q8WTV0 4 +Plasma lipoprotein particle clearance 0.6145616182864606 1.3329799973273504 0.1825383680844736 1.0 1.0 12 Q92945,Q9H4M9,P09601,Q8WTV0 4 +Response to manganese ion 0.6732521156261779 1.3323994257338974 0.1827289707257555 1.0 1.0 5 P05067 1 +Maintenance of protein location in cell 0.5300099854159201 1.3289086062778672 0.1838781241210898 1.0 1.0 23 P30536,P24390,Q9UH99,O43731 4 +Dendrite arborization 0.8788860252784672 1.3280343047055962 0.1841667743955053 1.0 1.0 3 Q13641 1 +Fatty acid transmembrane transport 0.6336361848490311 1.3268705019271971 0.1845515236859047 1.0 1.0 7 P23786 1 +Regulation of glycoprotein metabolic process 0.6122168886425807 1.321501140753109 0.1863343224113776 1.0 1.0 12 Q9NQX7,Q9BXS4,P35610,Q92542 4 +Cellular response to inorganic substance 0.4264863842488571 1.3167774429212842 0.1879132360367159 1.0 1.0 35 P30536,P05067,P09601,P46108 4 +Regulation of exocytosis 0.4323673381336431 1.3164824597903022 0.1880121617905206 1.0 1.0 38 Q4J6C6,Q15833,O00560,P09601,P0DP25,P04083 6 +Cellular response to vascular endothelial growth factor stimulus 0.6694157642102763 1.3158005070173904 0.1882410090671742 1.0 1.0 5 Q16539,O14786,P04083 3 +Cellular response to insulin like growth factor stimulus 0.8747306863650363 1.312184723232452 0.189457815068013 1.0 1.0 3 Q9BSK2,P46108 2 +Positive regulation of phosphatase activity 0.6684498610903177 1.3116204732265904 0.1896482216839623 1.0 1.0 5 Q15257,P0DP25 2 +Response to progesterone 0.6682494171521091 1.3107529960899755 0.1899412275118792 1.0 1.0 5 P30536,Q05086 2 +Chloride transport 0.5858258704147628 1.3096391698493242 0.1903179309444742 1.0 1.0 16 P30536,Q9UHG3 2 +Regulation of cell migration involved in sprouting angiogenesis 0.7012130447854021 1.3084966130078248 0.1907049226218768 1.0 1.0 4 P09601,P04083 2 +Positive regulation of cell migration involved in sprouting angiogenesis 0.7012130447854021 1.3084966130078248 0.1907049226218768 1.0 1.0 4 P09601,P04083 2 +Regulation of stress activated protein kinase signaling cascade 0.494922321542727 1.3083087581047177 0.1907686057541147 1.0 1.0 26 P49327,O15344,P05067,Q969S3,O75844,O00560,P78318 7 +Muscle cell cellular homeostasis 0.629276354634845 1.3072277251579305 0.1911353820412196 1.0 1.0 7 O95817,Q9Y281,P10253,P13473 4 +Porphyrin containing compound metabolic process 0.5852425582747952 1.3065484483300824 0.1913661145731258 1.0 1.0 16 P30536,P30519,P33527,P09601 4 +Neural precursor cell proliferation 0.4712292613218014 1.3060764289771467 0.1915265678109423 1.0 1.0 28 P55209,Q8NCG7,Q06481,Q9H0H5,O95456,O75306,Q8IXJ6,Q9UKA9 8 +Regulation of lymphocyte migration 0.628746024420862 1.304837493159471 0.1919481892435819 1.0 1.0 7 P05067,P46108 2 +Membrane protein ectodomain proteolysis 0.6252529213205053 1.3030421889188335 0.1925603585978086 1.0 1.0 8 Q9NZ08,Q92542 2 +Regulation of cd4 positive alpha beta t cell differentiation 0.87015782226552 1.2947502772103825 0.1954063897638696 1.0 1.0 3 Q9UDY8 1 +Regulation of regulated secretory pathway 0.5684558562957567 1.2944619562502782 0.1955059019843348 1.0 1.0 18 Q15833,P0DP25,P09601,Q4J6C6 4 +Positive regulation of membrane depolarization 0.6965675175586498 1.288849210172936 0.1974505141343956 1.0 1.0 4 P30536 1 +Export across plasma membrane 0.6140484779828372 1.2855993414296776 0.1985829267074246 1.0 1.0 10 P33527,P08183 2 +Cholesterol storage 0.8667282240689453 1.281680717698477 0.1999546717763416 1.0 1.0 3 Q9H4M9,Q8WTV0 2 +Positive regulation of exosomal secretion 0.6234702495367448 1.2810497658392257 0.2001761866603026 1.0 1.0 7 O00560,Q99816 2 +Tissue regeneration 0.6612956557918568 1.280651837942005 0.2003159834812224 1.0 1.0 5 Q7Z4V5,P04083,P58107 3 +Regulation of establishment or maintenance of cell polarity 0.6233609441367186 1.2805567520108587 0.2003493988517171 1.0 1.0 7 Q9NUQ9,Q14254,P63244 3 +Connective tissue development 0.4792669403548573 1.2787735576711723 0.2009768080053189 1.0 1.0 27 O15173,P11802,P43490,P16435,P06400,O75844,P04818,P35610,Q16539,Q15043,Q92896,Q8N0X7 12 +Positive regulation of oxidoreductase activity 0.6163621098319095 1.2781296960483093 0.2012036997955681 1.0 1.0 9 P0DP25,P00374,Q8WTV0 3 +Regulation of hormone metabolic process 0.660490419280848 1.2771654601447149 0.2015438383279784 1.0 1.0 5 O75844 1 +Negative regulation of amyloid beta clearance 0.8651555028423397 1.2756892992023496 0.2020653727695058 1.0 1.0 3 Q16850 1 +Cellular modified amino acid metabolic process 0.4656098504633434 1.2755571697446362 0.2021121026365668 1.0 1.0 58 O75874,Q8NBM8,O15217,Q92820,Q8NCC3,P00374,P23786,Q9H2D1,Q8N2K0,P41440,O60725,Q9NVH6,Q9UHG3 13 +Smad protein signal transduction 0.615484064302474 1.2740417328726508 0.2026486264390752 1.0 1.0 9 Q9UIQ6 1 +Peptidyl proline hydroxylation 0.6213355976277319 1.2714204236682642 0.2035791205938948 1.0 1.0 7 O75718,O15460,Q32P28 3 +Regulation of reactive oxygen species metabolic process 0.4283693650465909 1.2691474958088471 0.2043884630986838 1.0 1.0 31 Q9BSK2,P00374,P00403,P30536,P52789,P42785,Q16539,Q8IXJ6 8 +Keratan sulfate metabolic process 0.8633425669436762 1.2687843717259528 0.2045179805954515 1.0 1.0 3 P15586,P16278 2 +Regulation of muscle organ development 0.6169971431906107 1.2652272108152598 0.20578989078742 1.0 1.0 8 O75955,Q8IXJ6,P41440 3 +Negative regulation of phagocytosis 0.6222511205507442 1.2641733106978783 0.2061678280688226 1.0 1.0 6 P09429,Q9NT62,P63244,Q08722 4 +Ganglion development 0.8621235384067434 1.2641424713111122 0.2061788949140797 1.0 1.0 3 Q13509 1 +Dorsal root ganglion development 0.8621235384067434 1.2641424713111122 0.2061788949140797 1.0 1.0 3 Q13509 1 +Negative regulation of mapk cascade 0.4649786957321631 1.2604144349779889 0.2075198970366265 1.0 1.0 28 O75832,P30086,P04035,Q96P70,O00459,P21359,P30153,P57105,P78318,P04062,P56537 11 +Protein lipid complex subunit organization 0.6895865168607322 1.2593281536265812 0.2079118282605978 1.0 1.0 4 Q8WTV0 1 +Regulation of systemic arterial blood pressure 0.6158465013491684 1.2466491653347105 0.2125261658936836 1.0 1.0 7 P42785 1 +Lymphocyte mediated immunity 0.4180662445633775 1.2457671828095391 0.2128498808945693 1.0 1.0 35 P04439,Q9BY67,P46108,P01889,P53634,Q9UQ84,Q96FV9,P51809,P11279,Q9UDY8,Q9NQT5,P13051 12 +Regulation of cyclase activity 0.6180306069855088 1.2454077568944129 0.2129819034333286 1.0 1.0 6 P0DP25 1 +Positive regulation of skeletal muscle tissue development 0.8571915954556695 1.245371216830346 0.2129953284578196 1.0 1.0 3 P41440 1 +Positive regulation of muscle tissue development 0.8571915954556695 1.245371216830346 0.2129953284578196 1.0 1.0 3 P41440 1 +Regulation of lipoprotein metabolic process 0.6177094611325289 1.243979564552639 0.2135070841189461 1.0 1.0 6 Q5HYI8,P04062,P06756 3 +Microtubule anchoring at centrosome 0.6522944256236639 1.241675286997761 0.2143563915614093 1.0 1.0 5 Q86VS8,Q14203,Q9Y496,Q15154 4 +Regulation of myotube differentiation 0.6522473996955898 1.2414716438262807 0.2144315670791621 1.0 1.0 5 Q16539 1 +Protein targeting to membrane 0.4253376112286555 1.2411076395715055 0.2145659877503249 1.0 1.0 39 Q9H9H4,P43307,Q9Y3D6,Q9NQG6,O43681,Q7L5D6,O00560,P46379,Q9Y5Y5,Q9H0F7,O60725,Q15629,P27105 13 +Tetrapyrrole metabolic process 0.5501802161702783 1.235677917505319 0.2165783090147486 1.0 1.0 19 P30536,P30519,P33527,P09601 4 +Heart valve morphogenesis 0.6130651630227194 1.2340927554966812 0.217168342741884 1.0 1.0 7 Q9Y6N7,P06400,Q04721 3 +Protein localization to endoplasmic reticulum 0.4183316858860307 1.2314418195620214 0.2181576641348566 1.0 1.0 36 P24390,Q15629,O43731 3 +T cell activation involved in immune response 0.6096136279376734 1.2313784280620226 0.2181813612421121 1.0 1.0 8 Q9UDY8 1 +Walking behavior 0.6498349751524518 1.2310248028797206 0.2183135878908713 1.0 1.0 5 O75844,O15118 2 +Regulation of jnk cascade 0.5881863259575202 1.2283085004996626 0.2193311811649687 1.0 1.0 13 O00560 1 +Negative regulation of natural killer cell mediated immunity 0.8519544475223156 1.2254556297058952 0.2204035979737197 1.0 1.0 3 P46108,P01889 2 +Detection of external biotic stimulus 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 1.0 3 P01889,Q8WTV0 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 1.0 3 P01889,P10321 2 +Production of molecular mediator involved in inflammatory response 0.6048883444900989 1.224680756801421 0.2206955272716286 1.0 1.0 9 Q8IV08,Q06481 2 +Cranial nerve development 0.6481926878875142 1.2239131186142629 0.2209850042220991 1.0 1.0 5 Q9H061 1 +Pyrimidine nucleotide catabolic process 0.6806684449250334 1.22163189413423 0.2218468618429425 1.0 1.0 4 Q9H773 1 +Positive regulation of protein localization to cell surface 0.6795584807489762 1.2169420573732497 0.2236262623340414 1.0 1.0 4 Q92544,P08238 2 +O glycan processing 0.678545752730095 1.2126635220154374 0.2252584917925117 1.0 1.0 4 O43505 1 +Regulation of long term synaptic potentiation 0.6082547213999657 1.2123700651608675 0.2253707543944429 1.0 1.0 7 P05067 1 +Inositol phosphate metabolic process 0.6012438279317633 1.2076926675836803 0.2271654994808303 1.0 1.0 9 Q10713,Q9BW91 2 +Anion transport 0.4891597956835865 1.2030299776648457 0.2289647201615217 1.0 1.0 76 P21796,P30536,P45880,Q9H2D1,P33527,P07602,P08183,Q9Y277,P41440,Q9H0H5,Q15043,Q9Y619,Q9UHG3,Q15907,O00400,Q9BQT8,Q9UBX3,P51797,P04083,O43681,Q86VD7,Q8TB61 22 +Regulation of phospholipid metabolic process 0.5997606461303162 1.2007781804153426 0.229837257970821 1.0 1.0 9 Q8WTV0 1 +Cell recognition 0.4895782032801249 1.1993847980961223 0.2303783559046115 1.0 1.0 25 P45880,Q8WTV0 2 +Positive regulation of small molecule metabolic process 0.5648267972286423 1.198206868315361 0.230836492187775 1.0 1.0 16 P05067,P00403,P04083 3 +Response to interleukin 7 0.599189564375972 1.1981157158994593 0.2308719713807763 1.0 1.0 9 P67809,P07237,P46109 3 +Skeletal muscle contraction 0.6414648520412292 1.194782499708536 0.2321720194944592 1.0 1.0 5 P10253 1 +Adipose tissue development 0.5948072307971188 1.1944424814190155 0.2323049276801896 1.0 1.0 10 O15173,P35610,P11802,P43490 4 +Amine catabolic process 0.640925509319264 1.1924475771741083 0.2330857944369695 1.0 1.0 5 Q6QHF9,P49366 2 +Aminoglycan biosynthetic process 0.5943750203003721 1.192393402122132 0.2331070261474646 1.0 1.0 10 Q8NCH0,Q8N6G5,O43505,P06865 4 +Multicellular organism aging 0.5854923565115824 1.190405736061529 0.2338869596363029 1.0 1.0 12 O75844 1 +Membrane docking 0.4312631426405167 1.1894981211419997 0.2342437099218088 1.0 1.0 30 O60499,O15498,Q13190,Q7Z6M1 4 +Nadh dehydrogenase complex assembly 0.4433819828627713 1.1886708076953043 0.2345692323513302 1.0 1.0 29 O43676,Q8N183,Q9P0J0,O75306,O95168,Q9BU61,Q8TB37,Q9H061,Q96CU9,Q9Y6M9 10 +Carboxylic acid transport 0.4128886419743544 1.1855071727149114 0.2358169803924172 1.0 1.0 36 Q9BQT8,Q9UBX3,Q7L0J3,Q9H2D1,P33527,P41440,P04083,P07602,Q9Y619 9 +Regulation of neurotransmitter uptake 0.6719257645309051 1.184708056747913 0.2361328958707813 1.0 1.0 4 P41440 1 +Ceramide biosynthetic process 0.5992515581881411 1.183845792234038 0.2364741115702668 1.0 1.0 8 Q96G23,P04062,Q13510 3 +Regulation of plasma lipoprotein particle levels 0.5792888526888436 1.1837977733703289 0.2364931238594334 1.0 1.0 13 Q92945,Q9H4M9,P09601,Q8WTV0 4 +Cellular response to xenobiotic stimulus 0.4764984797477554 1.182006675101127 0.237203052269153 1.0 1.0 26 O15217,P16435,P07099,P06400,P33993,O00170,P27544,P12004,P46109,O43169 10 +Icosanoid transport 0.6710106531505928 1.180845563534858 0.2376640798658749 1.0 1.0 4 P33527 1 +Cellular iron ion homeostasis 0.561222911884837 1.1790588223978264 0.2383747538238616 1.0 1.0 16 Q8N511,P30626,Q9Y487,Q15904,P09601,P02792 6 +Blood vessel endothelial cell migration 0.5239037495172014 1.1782332874132675 0.2387036154389141 1.0 1.0 21 Q4VCS5,P42785,P09601,Q8WTV0,Q16539,O14786,P04083 7 +Hippo signaling 0.6001108242856209 1.1755836933884491 0.239761274880436 1.0 1.0 7 Q01085,Q4VCS5,Q13043,Q16539,Q8TD19 5 +Positive regulation of ubiquitin protein ligase activity 0.6693349753694524 1.1737742436550678 0.240485463167055 1.0 1.0 4 P53350,Q12834,P63208 3 +Negative regulation of neuron apoptotic process 0.5052121841845 1.1731799425430725 0.2407236536071948 1.0 1.0 23 P50897,P09601,P04062,Q01105 4 +Icosanoid biosynthetic process 0.5967345345454902 1.1722972126868714 0.2410777502892536 1.0 1.0 8 Q8NCG7,P09960,P04083 3 +T cell extravasation 0.8365650969529099 1.1670593714922222 0.2431863937737319 1.0 1.0 3 P46108,P46109 2 +Protein insertion into membrane 0.4634144600545416 1.1665344917010751 0.243398411604566 1.0 1.0 27 Q9NS69,Q15629,Q9Y584 3 +Regulation of synapse assembly 0.5946205693384935 1.162597780849236 0.244992731583741 1.0 1.0 8 P05067,Q13641 2 +Tetrahydrobiopterin metabolic process 0.8352766786185607 1.162180235583989 0.2451622611773021 1.0 1.0 3 P35270 1 +Nuclear transcribed mrna catabolic process exonucleolytic 0.5691314600929075 1.1589734499787712 0.2464670074024244 1.0 1.0 14 Q9NQT5,Q969T7,Q6PGP7,Q15477 4 +Chaperone mediated autophagy 0.5906355335480326 1.1582309929325156 0.2467697836634466 1.0 1.0 9 O95817,P10619,Q05639,P13473 4 +Cellular hormone metabolic process 0.5203083967088098 1.1567786151515267 0.2473628209843779 1.0 1.0 21 P30536,P42892,Q9HB40,O95470 4 +Myotube differentiation 0.5683395955305586 1.1549333742063392 0.2481177111754271 1.0 1.0 14 O75955,Q9H4M9,Q8IV08,P41440,Q16539 5 +Polyol metabolic process 0.4719836433165287 1.1510018130635455 0.2497314896497366 1.0 1.0 26 O15269,P35270,Q10713,P00374,Q13510,P29218,Q9BW91,P04062 8 +Arf protein signal transduction 0.6303271276213912 1.1465840594998575 0.251553567681599 1.0 1.0 5 Q8N6T3,Q15555,Q92538 3 +Regulation of animal organ morphogenesis 0.5908861582467578 1.145463753035041 0.2520171021849093 1.0 1.0 8 Q8TAA9 1 +Regulation of myeloid cell apoptotic process 0.6299951936389878 1.1451483986435729 0.2521476895808985 1.0 1.0 5 P04083 1 +Dendritic cell differentiation 0.661935579576814 1.1425727981213154 0.2532160048767358 1.0 1.0 4 P01889 1 +Cytochrome complex assembly 0.5838544553748227 1.1425114532730622 0.2532414880557367 1.0 1.0 10 Q9BSK2,Q69YU5 2 +Phosphatidylglycerol metabolic process 0.5797892636866524 1.1414296159549489 0.253691186127698 1.0 1.0 11 Q9HCL2,P40939 2 +Protein insertion into er membrane 0.5754404381924147 1.1410326124306684 0.2538563518882903 1.0 1.0 12 O43681,P46379,Q7L5D6,Q15629 4 +Extracellular matrix disassembly 0.5922243183438362 1.1399577019290064 0.2543039235858475 1.0 1.0 7 O75955,P41440 2 +Phosphatidic acid metabolic process 0.5917697883326123 1.1379046331217777 0.2551603064345213 1.0 1.0 7 Q9HCL2 1 +Negative regulation of receptor mediated endocytosis 0.5849329025322291 1.1316420000865923 0.2577849748937395 1.0 1.0 9 O00560 1 +Anaphase promoting complex dependent catabolic process 0.5777190424737414 1.131442649623818 0.2578688290476307 1.0 1.0 11 P53350,Q13042,Q12834,Q9H1A4,P30260,Q9UJX4,Q16763,Q9UJX3,Q9UJX2 9 +Regulation of gliogenesis 0.5685490270336468 1.1300532730894437 0.2584537774152096 1.0 1.0 13 P30536,Q8IXJ6 2 +Neurotransmitter transport 0.4790806722630482 1.129454168500939 0.2587062930343338 1.0 1.0 25 Q4J6C6,O75955,P50897,Q15833,P0DP25,P41440 6 +Regulation of amyloid beta clearance 0.5909960309995217 1.1251182026831337 0.2605389488278917 1.0 1.0 6 Q16850 1 +Nadp metabolic process 0.5505756619112839 1.1224770837699631 0.2616596458248112 1.0 1.0 16 P48735 1 +Positive regulation of erad pathway 0.6568390259338996 1.1211082542090556 0.2622417856043926 1.0 1.0 4 P46379 1 +Steroid metabolic process 0.4593166148174899 1.1200127282809906 0.2627083381161816 1.0 1.0 65 O15118,P30536,Q16850,Q53GQ0,O14975,Q9BQE5,Q9UHI6,Q13510,P35610,P37268,Q14739,Q8WTV0,P34913,P61916,P04035,P04062,O95470,P05067,P14324,Q15392 20 +Central nervous system neuron axonogenesis 0.5897923490788415 1.1197632733185543 0.2628146537628986 1.0 1.0 6 P08238,P07900,Q99622 3 +Negative regulation of hormone secretion 0.58951557790987 1.1185320354957813 0.2633398322758287 1.0 1.0 6 Q8N183,P40939 2 +Negative regulation of peptide secretion 0.58951557790987 1.1185320354957813 0.2633398322758287 1.0 1.0 6 Q8N183,P40939 2 +Dermatan sulfate proteoglycan metabolic process 0.8236858112278502 1.1183682946314295 0.2634097296682767 1.0 1.0 3 Q8N6G5 1 +Morphogenesis of a polarized epithelium 0.5655736837758478 1.1151655434511831 0.2647794885992001 1.0 1.0 13 Q8TAA9 1 +Aortic valve morphogenesis 0.6230567014260597 1.1151527368856886 0.2647849755717872 1.0 1.0 5 Q9Y6N7,P06400 2 +Regulation of skeletal muscle tissue development 0.622714464837706 1.1136740100088782 0.2654190630125579 1.0 1.0 5 O75955,P41440 2 +Activation induced cell death of t cells 0.6549527077216171 1.1131701513358354 0.2656353595020779 1.0 1.0 4 Q9HCL2,Q96EY1 2 +T cell homeostasis 0.6549527077216171 1.1131701513358354 0.2656353595020779 1.0 1.0 4 Q9HCL2,Q96EY1 2 +Regulation of hippo signaling 0.6545566502462996 1.1115039022281796 0.2663515113196384 1.0 1.0 4 Q16539,Q01085,Q8TD19 3 +Skeletal muscle tissue regeneration 0.6537876771691582 1.1082692329300292 0.2677455587668338 1.0 1.0 4 P04083,Q7Z4V5 2 +Positive regulation of release of sequestered calcium ion into cytosol 0.5849420228796738 1.1070702091580715 0.2682635744596475 1.0 1.0 7 P0DP25 1 +Positive regulation of calcium ion transport into cytosol 0.5849420228796738 1.1070702091580715 0.2682635744596475 1.0 1.0 7 P0DP25 1 +Regulation of protein deubiquitination 0.5867861607895434 1.1063913584887757 0.2685571641888105 1.0 1.0 6 P19474,Q96J02 2 +Peripheral nervous system axon regeneration 0.6523588874973067 1.1022607401310067 0.2703483321709101 1.0 1.0 4 P30536 1 +Regulation of phospholipid catabolic process 0.9806153846153848 1.1012870288426289 0.2707717547353589 1.0 1.0 2 Q8WTV0 1 +Cd4 positive alpha beta t cell activation 0.5836306567270964 1.1011497383358508 0.2708314926468107 1.0 1.0 7 Q9UDY8 1 +Regulation of oxidoreductase activity 0.5521667121722151 1.0999702332558343 0.2713450916051378 1.0 1.0 15 P06280,P0DP25,Q8WTV0 3 +Granulocyte activation 0.5833307980587361 1.0910257602839617 0.2752615476725362 1.0 1.0 6 P04083 1 +Negative regulation of proteasomal protein catabolic process 0.5008190972222711 1.0903032524037446 0.2755795829924681 1.0 1.0 22 P49069,O15372,O00560,P46379,Q92530,Q96HY6,Q9UL15 7 +Entry of bacterium into host cell 0.6171084901694124 1.0894643853575896 0.2759491520104347 1.0 1.0 5 Q9BTY2 1 +Homologous chromosome pairing at meiosis 0.5758331159957522 1.089229330155853 0.2760527679056834 1.0 1.0 9 P46379 1 +Regulated exocytosis 0.393600035963306 1.0881703717285325 0.2765199018623181 1.0 1.0 32 Q15907,Q4J6C6,O43760,Q15833,P09601,P0DP25,P11279 7 +Cardiac muscle cell proliferation 0.6490019168015304 1.0881526803953283 0.27652771054098 1.0 1.0 4 Q16539,P10644 2 +Negative regulation of nervous system development 0.5164509173682659 1.086559080085865 0.2772317175714172 1.0 1.0 20 Q96G23,P31150,Q04917,P30536,Q9UBS4,Q15375,Q06481,O14786,Q86VS8,Q8IXJ6,Q8N0X7 11 +Specification of symmetry 0.5718591249997533 1.0856558958653468 0.2776312601973765 1.0 1.0 10 Q9Y366,Q9H0F7 2 +Myoblast fusion 0.5801878972322627 1.0856101162467142 0.277651522215792 1.0 1.0 7 Q16539,Q9H4M9,P41440 3 +Syncytium formation 0.5801878972322627 1.0856101162467142 0.277651522215792 1.0 1.0 7 Q16539,Q9H4M9,P41440 3 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.574924865298885 1.0849979071309617 0.2779225822074451 1.0 1.0 9 Q6PGP7,Q15477 2 +Thymus development 0.5818981959013355 1.084656756132905 0.2780737074127293 1.0 1.0 6 O75844 1 +Response to catecholamine 0.563632253296944 1.083049282925764 0.2787865486811982 1.0 1.0 12 P05067,Q92542 2 +Lactation 0.5633753929763449 1.081788562395554 0.2793464899956017 1.0 1.0 12 Q13505,P00403 2 +Selective autophagy 0.4404669228064932 1.0808719043987929 0.2797540978456347 1.0 1.0 28 O15269,Q16543,P21796,Q9NQ88,P27544,Q709C8,Q9Y4P1,O95817,Q5T8D3,Q13137 10 +Regulation of lipid catabolic process 0.5740333132405002 1.0808446890977366 0.2797662057763934 1.0 1.0 9 O75874,Q8WTV0 2 +Negative regulation of macroautophagy 0.5624288176492627 1.0771428852166998 0.2814164366161691 1.0 1.0 12 Q9NQ88,P09601,O15118 3 +Organelle disassembly 0.4228616232619205 1.0769623849246646 0.2814970705723945 1.0 1.0 48 Q9Y3D6,Q16543,P21796,P30536,Q92538,P52789,Q9NQ88,Q709C8,P04062,Q9BWH2,Q13190 11 +Reelin mediated signaling pathway 0.8124678612994615 1.0761265091957155 0.281870681378868 1.0 1.0 3 P46108 1 +Sterol transport 0.5145779954411436 1.075659896265506 0.2820793892707187 1.0 1.0 20 P30536,O15118,Q8WTV0 3 +Transforming growth factor beta production 0.6458070834557881 1.0747385631722033 0.282491793330665 1.0 1.0 4 P08238,O75787 2 +Regulation of mast cell activation 0.8109347288735348 1.0703673386827826 0.2844539947658961 1.0 1.0 3 P09601 1 +Regulation of mast cell activation involved in immune response 0.8109347288735348 1.0703673386827826 0.2844539947658961 1.0 1.0 3 P09601 1 +Cytoplasmic sequestering of nf kappab 0.6447044334975307 1.0701118915431596 0.2845689471198631 1.0 1.0 4 Q9UNN5,Q9UN86,O75832 3 +Positive regulation of blood vessel endothelial cell migration 0.5707667767987644 1.0656316431585142 0.2865901891661941 1.0 1.0 9 Q16539,P09601,P04083 3 +Nerve development 0.5706932280387074 1.0652891839369354 0.2867450858426497 1.0 1.0 9 P42892,Q9H061 2 +Pteridine containing compound metabolic process 0.5331097341480131 1.0621114123426054 0.2881851097779464 1.0 1.0 17 Q92820,Q9H2D1,P35270,P41440 4 +Neuron maturation 0.5697938686432333 1.061101856663262 0.2886436141930666 1.0 1.0 9 O75503 1 +Protein deneddylation 0.5697894301091495 1.0610811926361643 0.2886530041940942 1.0 1.0 9 Q9UNS2,Q92905,O14656,Q9UBW8,Q9BT78,Q99627 6 +Microglia differentiation 0.9676923076923072 1.056765096331475 0.2906188075398277 1.0 1.0 2 P04062 1 +Retinal ganglion cell axon guidance 0.6414997838094776 1.0566746132963163 0.2906601149785437 1.0 1.0 4 O14786,Q15375 2 +Cell maturation 0.4370157670051653 1.0555748208227915 0.291162509507227 1.0 1.0 28 Q9Y2W6,P05067,P06400,P11413,O75503,Q12768,O95696,P04818,P04062,Q15645,Q8IXJ6 11 +3 utr mediated mrna destabilization 0.5753445644828008 1.0555358826653751 0.291180307483839 1.0 1.0 6 Q9HCE1 1 +Negative regulation of chemotaxis 0.5750733664196754 1.054331429433574 0.2917312040868756 1.0 1.0 6 Q9Y6N7,O14786,O94813 3 +Hindbrain development 0.3932137183148634 1.051875886012188 0.2928564967056932 1.0 1.0 34 P54802,P46108,P04062,Q92542,O95456 5 +Phospholipid homeostasis 0.9655384615384608 1.049370616521308 0.2940075764113494 1.0 1.0 2 Q9HCL2 1 +Positive regulation of macroautophagy 0.5018375650838102 1.0465596573463471 0.2953027166531115 1.0 1.0 21 O15269,P21796,Q9UIL1,P09601,P27544,Q13137 6 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.5167592279087917 1.0458207588081616 0.2956437950279782 1.0 1.0 19 P49069,O15372,O00560,P46379,Q96HY6,Q9UL15 6 +Prostate gland growth 0.8042448493693536 1.0452800750722548 0.295893543756758 1.0 1.0 3 P07602 1 +Negative regulation of cytokine production 0.4560791734430426 1.041751668037924 0.2975268274276708 1.0 1.0 26 P30536,P09601,P04062,P04083 4 +Positive regulation of release of cytochrome c from mitochondria 0.6059764636351839 1.041475588441641 0.2976548771173013 1.0 1.0 5 Q96A26 1 +Protein processing involved in protein targeting to mitochondrion 0.8024982425630646 1.0387423419456097 0.2989245831945406 1.0 1.0 3 Q10713 1 +Peptide transport 0.3915640579608541 1.0378896313145107 0.2993214413234537 1.0 1.0 34 O43768,Q15907,Q6ZWJ1,Q03518,Q8N183,Q8NE86,P30626,P40939,P33527,P04083,P00367 11 +Postsynaptic signal transduction 0.6363916256157574 1.035286435651982 0.3005351626106742 1.0 1.0 4 P52294,P52292,P46109 3 +Glycosylceramide catabolic process 0.9609230769230755 1.033551998934515 0.3013456494300668 1.0 1.0 2 P04062 1 +Glycosylceramide metabolic process 0.9609230769230755 1.033551998934515 0.3013456494300668 1.0 1.0 2 P04062 1 +Cellular response to exogenous dsrna 0.5703766332158913 1.033481216914368 0.3013787561199641 1.0 1.0 6 Q9NUD5,P41440 2 +Regulation of myeloid leukocyte mediated immunity 0.5663009764244097 1.0327780362420675 0.3017077845290121 1.0 1.0 8 P09601 1 +Regulation of aerobic respiration 0.5490913558409846 1.0327622446663878 0.3017151763800243 1.0 1.0 13 P14406 1 +Protein targeting to vacuole 0.5070826650516279 1.032062978190087 0.3020426156632649 1.0 1.0 20 Q14108,P20645,Q9H9H4,P13473 4 +Regulation of toll like receptor signaling pathway 0.5657396920900887 1.0302098234763677 0.3029115193043461 1.0 1.0 8 Q06481,P41440 2 +N terminal peptidyl methionine acetylation 0.7999384425977241 1.029170261733321 0.3033996740027547 1.0 1.0 3 Q14CX7,Q9BXJ9 2 +Sulfate transport 0.7996306555863357 1.028020105617151 0.3039403702143857 1.0 1.0 3 Q9UBX3,Q9H0H5 2 +Regulation of nitric oxide metabolic process 0.5555009136709995 1.024369127918778 0.3056609580122433 1.0 1.0 11 P06280,Q92945,P30536,P08238,P50570,Q08722 6 +Regulation of cd4 positive alpha beta t cell activation 0.6335055630774595 1.0232202944088036 0.3062036995472308 1.0 1.0 4 Q9UDY8 1 +Cellular response to molecule of bacterial origin 0.453289079682183 1.022597192362968 0.3064983376409702 1.0 1.0 26 Q9NUQ9,P11802,P30536,O43823,Q8WTV0,Q16539,Q9UDY8,P14174,Q8IXJ6 9 +Establishment of protein localization to vacuole 0.4977156616936954 1.0219864495437352 0.3067873138367676 1.0 1.0 21 Q14108,P20645,Q9H9H4,P13473 4 +Post translational protein modification 0.5545389422330745 1.0197410250587482 0.3078512994342612 1.0 1.0 11 O60725,Q32P28,Q9HA64 3 +Mononuclear cell migration 0.4802214556561872 1.0159687315330117 0.3096442767999412 1.0 1.0 23 P05067,P46108,Q9Y624,P04062,P46109,P04083 6 +Negative regulation of neural precursor cell proliferation 0.5654888506333036 1.0118035881834433 0.3116319740097473 1.0 1.0 6 Q8IXJ6 1 +Epithelial cell differentiation involved in kidney development 0.5988998239040257 1.0110436638302 0.3119955319447889 1.0 1.0 5 Q04721,P42224 2 +Cell differentiation involved in kidney development 0.5988998239040257 1.0110436638302 0.3119955319447889 1.0 1.0 5 Q04721,P42224 2 +Macromolecule deacylation 0.3921940384070105 1.0106392648603155 0.3121891157178231 1.0 1.0 36 P50897,Q9UMR5,Q6UWU4,Q8IXJ6 4 +Lysosomal transport 0.4092249508165509 1.0103132446741412 0.3123452375717033 1.0 1.0 45 Q99816,P11279,O15118,Q9UQN3,Q14108,P20645,Q9UNK0,P07602,P13473 9 +Toxin transport 0.5395786420564425 1.0083313765878663 0.3132954048427314 1.0 1.0 14 O14786,Q9C0I1,Q93050 3 +Epithelial cell proliferation 0.4085066905664917 1.0043300101918815 0.315219573148414 1.0 1.0 45 Q6ZWJ1,Q6UWU4,Q9Y366,Q9Y6N7,P06400,P57105,Q92542,Q8WTV0,P09601,O14786,Q86VI3 11 +Sphingolipid translocation 0.952 1.0030784445399237 0.3158230140610514 1.0 1.0 2 P33527 1 +Xenobiotic transport across blood brain barrier 0.952 1.0030784445399237 0.3158230140610514 1.0 1.0 2 P33527 1 +Sprouting angiogenesis 0.5383219454476452 1.00193942052225 0.3163728520215709 1.0 1.0 14 Q9Y6N7,P57105,P09601,P04083,O14786 5 +Learning 0.4937752964971561 0.9985118502430206 0.3180312210783689 1.0 1.0 21 P50897,P05067,P04035,Q13641 4 +Protein targeting to lysosome 0.5323113899458362 0.996775972551759 0.3188732635027183 1.0 1.0 15 Q14108,P13473 2 +Endothelial cell proliferation 0.5207986307223605 0.9953822655429112 0.3195503806048498 1.0 1.0 17 P57105,Q8WTV0 2 +Phosphatidylcholine catabolic process 0.9495384615384578 0.9946986829854272 0.3198828352049399 1.0 1.0 2 Q8WTV0 1 +Regulation of macroautophagy 0.4312958204735482 0.9946085734551732 0.3199266760825312 1.0 1.0 58 O15269,Q8IYI6,Q9NRR5,O15118,P21796,Q9Y5X3,Q9Y487,Q93050,P04632,Q9NQ88,Q9UIL1,P09601,Q709C8,Q9UPT5,P04062,Q13137 16 +Neutral amino acid transport 0.6265394088669884 0.9941550238668446 0.320147400661634 1.0 1.0 4 Q96NB2,Q15758,Q9H9B4 3 +Escrt complex disassembly 0.5947236422624862 0.9931175823345942 0.3206526565403238 1.0 1.0 5 Q9UN37,Q9UQN3 2 +Protein import into mitochondrial matrix 0.5574613458328109 0.9923681688500096 0.3210179606991912 1.0 1.0 8 Q99595,O14925 2 +Positive regulation of exocytosis 0.5305206054347188 0.9874872563514164 0.3234038272193424 1.0 1.0 15 P11279,O00560,Q99816,P51809 4 +Necrotic cell death 0.524958479647781 0.9865211788756156 0.3238774276615319 1.0 1.0 16 P30536,Q13510 2 +Vacuolar transport 0.4192563047744291 0.9857074999532852 0.3242766680629496 1.0 1.0 52 O15118,Q9UQN3,Q92572,P20645,Q709C8,P51809,Q9P253,P07602,Q8WUH2,Q99816,Q9UNK0,Q9H9H4,P11717,Q14108,Q96RL7,Q9UN37,Q86VS8,P11279,P13473 19 +Leukocyte mediated immunity 0.4098651561804768 0.9845567097934383 0.324841862661825 1.0 1.0 47 P04439,P46108,P01889,P53634,Q9UQ84,Q15833,Q96FV9,P09601,P11279,Q9UDY8,Q9NQT5,P13051 12 +Protein neddylation 0.5532681303364514 0.9842842868288886 0.3249757532102983 1.0 1.0 9 Q8IWE4,Q92564 2 +Negative regulation of immune response 0.4476452030037486 0.9838778646887252 0.3251755684701303 1.0 1.0 26 P19474,P28070,P46108,P01889,Q96FV9,P09601,P04083,Q16539 8 +Regulation of autophagosome maturation 0.7873457190576014 0.982258984824222 0.3259722751870022 1.0 1.0 3 Q13137 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.7872328756522734 0.9818400392329538 0.3261786593049609 1.0 1.0 3 P11279 1 +Positive regulation of natural killer cell mediated immunity 0.7872328756522734 0.9818400392329538 0.3261786593049609 1.0 1.0 3 P11279 1 +Long term synaptic potentiation 0.5521354897580224 0.9790303215900326 0.3275649977488464 1.0 1.0 9 P05067 1 +Membrane raft organization 0.5511664688814697 0.9745366991742684 0.3297901264257528 1.0 1.0 9 P50897,P41440,O15118 3 +Positive regulation of carbohydrate metabolic process 0.5532416450602659 0.9731099853191012 0.3304986418062521 1.0 1.0 8 P05067 1 +Mitophagy 0.5276585537830218 0.9726509138029446 0.3307268290345824 1.0 1.0 15 Q16543,P21796,Q9NQ88,Q709C8,Q9Y4P1 5 +Positive regulation of toll like receptor signaling pathway 0.5891508104792218 0.9692397366440824 0.3324255891598815 1.0 1.0 5 P41440 1 +Mitochondrial transmembrane transport 0.4208043196371148 0.9682756894639792 0.3329067026204759 1.0 1.0 54 Q9BSK2,Q9Y619,P21796,P23786,O75964,Q99595,Q9H2D1,O43772 8 +Kidney morphogenesis 0.587839178441901 0.9636275965208048 0.3352326660105273 1.0 1.0 5 O75844 1 +Protein maturation by iron sulfur cluster transfer 0.5877081929952547 0.9630673143121168 0.3355137434136521 1.0 1.0 5 Q9UMS0 1 +Myeloid leukocyte activation 0.5086077892904365 0.9625384682417388 0.3357791893923783 1.0 1.0 18 P05067,P53634,Q15833,Q04721,P09601,P51809,P04083 7 +Negative regulation of inflammatory response to antigenic stimulus 0.5874899459027418 0.9621338456223472 0.335982374624423 1.0 1.0 5 Q16539 1 +Folic acid containing compound metabolic process 0.5304255847953168 0.9618226307351226 0.3361387080720668 1.0 1.0 14 Q92820,Q9H2D1,P41440 3 +Atp synthesis coupled electron transport 0.3877942896151982 0.9574148820002732 0.338357889879322 1.0 1.0 37 O75380,P00403,O43676,Q9UDW1,O95168,O95182,O75306 7 +Positive regulation of ubiquitin protein transferase activity 0.5337862168258848 0.9564625106062428 0.3388386160846872 1.0 1.0 13 P53350,P61088,Q12834,Q9UNE7,Q8IWE4,Q9BTE7,P63208,Q92564 8 +Regulation of multicellular organism growth 0.5133154119648351 0.9549099008749764 0.3396232624046238 1.0 1.0 17 P05067,Q7Z5J4,O75844,Q9HCL2,O95470 5 +Ribonucleoside diphosphate catabolic process 0.7798905497294739 0.9546398825131928 0.339759841112575 1.0 1.0 3 Q9BW91 1 +Nucleoside diphosphate catabolic process 0.7798905497294739 0.9546398825131928 0.339759841112575 1.0 1.0 3 Q9BW91 1 +Positive regulation of cholesterol storage 0.9375384615384564 0.9540263227032304 0.3400703183408327 1.0 1.0 2 Q8WTV0 1 +Heart valve development 0.545857584893687 0.9499419063851056 0.342141771849481 1.0 1.0 9 Q9Y6N7,P06400,Q04721 3 +Protein processing 0.4075185690069022 0.9497090723965492 0.342260098629735 1.0 1.0 48 Q10713,Q99797,P42892,Q8TAD4,O75503,Q9BXS4,O75844,Q15392,Q92542,Q92896 10 +Negative regulation of neuron death 0.3886091979738519 0.9482872871241408 0.3429832210000736 1.0 1.0 38 Q01105,P63244,P50897,Q9NQ88,P09601,P04062,O14786 7 +Neurotransmitter uptake 0.550817898838163 0.9469039828028292 0.3436877082599889 1.0 1.0 6 P41440 1 +Regulation of epithelial cell migration 0.392174068848939 0.94645075339784 0.3439187291263268 1.0 1.0 40 P42785,P09601,P57105,Q8WTV0,Q16539,P04083 6 +Striated muscle cell proliferation 0.5838015721375522 0.946371805783376 0.3439589805758705 1.0 1.0 5 Q16539,P10644,P06493 3 +Organic acid transport 0.4106447494523783 0.945026635234658 0.3446452780829983 1.0 1.0 50 Q9Y3D6,Q9Y619,Q9BQT8,Q96H78,Q9UBX3,P23786,Q9H2D1,P33527,P41440,P04083,O43772,P08183,O14975 13 +Regulation of t helper cell differentiation 0.9341538461538468 0.9426115172359852 0.3458796466321954 1.0 1.0 2 Q9UDY8 1 +Positive regulation of cd4 positive alpha beta t cell differentiation 0.9341538461538468 0.9426115172359852 0.3458796466321954 1.0 1.0 2 Q9UDY8 1 +Positive regulation of cd4 positive alpha beta t cell activation 0.9341538461538468 0.9426115172359852 0.3458796466321954 1.0 1.0 2 Q9UDY8 1 +Positive regulation of t helper cell differentiation 0.9341538461538468 0.9426115172359852 0.3458796466321954 1.0 1.0 2 Q9UDY8 1 +Regulation of heterotypic cell cell adhesion 0.613676367118474 0.9407384362703886 0.3468389167287149 1.0 1.0 4 O75955,P41440 2 +Regulation of amyloid fibril formation 0.5460562960644879 0.940375228065626 0.347025124165931 1.0 1.0 8 Q9UHV9,Q9NQP4,P05067 3 +Negative regulation of cell development 0.4596161248760038 0.9402558957635004 0.3470863166287625 1.0 1.0 24 Q96G23,P31150,Q04917,P30536,Q9UBS4,Q15375,Q06481,O14786,Q86VS8,Q8IXJ6,Q8N0X7 11 +Pulmonary valve morphogenesis 0.7756232686980628 0.9388875846934616 0.347788464183173 1.0 1.0 3 Q9Y6N7,Q04721 2 +Pulmonary valve development 0.7756232686980628 0.9388875846934616 0.347788464183173 1.0 1.0 3 Q9Y6N7,Q04721 2 +Receptor mediated endocytosis 0.4151772454375909 0.9370444526384476 0.3487356924550813 1.0 1.0 53 P50897,Q14108,O00560,Q5VW38,Q7Z6M1 5 +Acylglycerol homeostasis 0.9323076923076864 0.9363963943241204 0.3490691337267408 1.0 1.0 2 Q8WTV0 1 +Substrate dependent cell migration 0.5402575771979866 0.9363819162041463 0.3490765853721238 1.0 1.0 10 Q9Y6N7,O14786,O00560,O94813 4 +Muscle cell migration 0.5332361340838645 0.9342766721867272 0.350161194382701 1.0 1.0 12 O14786,P46108,P04083 3 +Toll like receptor 3 signaling pathway 0.7734687596183458 0.9309509483206438 0.3518789381771166 1.0 1.0 3 O75955,P41440 2 +Regulation of toll like receptor 3 signaling pathway 0.7734687596183458 0.9309509483206438 0.3518789381771166 1.0 1.0 3 O75955,P41440 2 +Regulation of nucleotide biosynthetic process 0.5438137269178762 0.9301756232343976 0.3522801610385522 1.0 1.0 8 Q15118,P00403 2 +Ovulation cycle 0.5430985413751607 0.9269246859163652 0.3539656391213164 1.0 1.0 8 O94813,P42575,O95470,P04083 4 +Synaptonemal complex organization 0.5441089729686279 0.9233835104042144 0.3558073818471916 1.0 1.0 7 P53350,P54652,P46379,Q15645 4 +Positive regulation of protein export from nucleus 0.5395589123630067 0.9208208524965352 0.3571439661807902 1.0 1.0 9 O95817,Q9C0E2,Q05D32 3 +Polyamine biosynthetic process 0.9273846153846086 0.9198623824699386 0.3576446789320635 1.0 1.0 2 Q6QHF9 1 +Regulation of autophagy of mitochondrion 0.5171888197543961 0.9184905518778672 0.3583621031136479 1.0 1.0 15 P30536,Q709C8,P21796 3 +Carbohydrate transport 0.5117459581025542 0.9166962277661156 0.3593018433588955 1.0 1.0 16 Q16539,Q6ZWJ1,Q06481,P52789 4 +Negative regulation of response to wounding 0.542470744630965 0.916059647889354 0.3596356107398211 1.0 1.0 7 P46108 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.5293999793576973 0.9155928111501208 0.3598805032563672 1.0 1.0 12 P08238,Q13573,P50570,O00560,Q9UPN9,Q92896 6 +Protein localization to vacuole 0.4557164702745993 0.9151404386135248 0.3601179080450589 1.0 1.0 24 Q14108,P20645,Q9H9H4,P13473 4 +Regulation of cell shape 0.4278934319395299 0.9149275894065484 0.3602296451673605 1.0 1.0 27 O75844,Q9UQB8,P46108 3 +Ovulation cycle process 0.5763836127494714 0.9147552306346872 0.3603201424144826 1.0 1.0 5 P42575,O95470 2 +Regulation of nucleotide metabolic process 0.5058084760106017 0.914405520572488 0.3605038020857454 1.0 1.0 17 P05067,Q15118,P27144,P00403 4 +Mitochondrial genome maintenance 0.5378711533736198 0.9130299638614982 0.3612267826841822 1.0 1.0 9 Q9BSK2 1 +Neurotransmitter secretion 0.4931324338179743 0.9120431751421492 0.3617459899181847 1.0 1.0 19 P50897,P0DP25,Q4J6C6 3 +Bone remodeling 0.5349531262620947 0.9114604026886066 0.3620528401517986 1.0 1.0 10 P02786,P21359,Q04721,O14773,Q9UBB6 5 +Negative regulation of protein serine threonine kinase activity 0.5104982047843085 0.9101190776887256 0.3627597144608778 1.0 1.0 16 P04062,P10644,P04035,O95373 4 +Response to cell cycle checkpoint signaling 0.7670903613363085 0.9075229984615536 0.3641302931838548 1.0 1.0 3 O75844 1 +Production of sirna involved in rna interference 0.6056201691829562 0.9074788039962192 0.364153653279843 1.0 1.0 4 Q15631 1 +Interferon gamma mediated signaling pathway 0.5745594046380924 0.9069987111266808 0.3644074788063403 1.0 1.0 5 Q16543,P42224 2 +Negative regulation of protein targeting to mitochondrion 0.7663896583564193 0.90495575688044 0.3654888265372311 1.0 1.0 3 O95817,O95429 2 +Negative regulation of axonogenesis 0.5401564398246705 0.8999494400437369 0.3681471578228876 1.0 1.0 6 O14786,P31150,Q15375 3 +Regulation of fat cell differentiation 0.522222760262302 0.8990571840047937 0.3686222024100871 1.0 1.0 13 Q16539,Q8N4Q0,Q8IXJ6 3 +Skin development 0.3751314905511518 0.8988037849046717 0.3687571837242926 1.0 1.0 34 O75844,Q15392,P04062,Q13510 4 +Negative regulation of cellular protein catabolic process 0.3942513681136221 0.8985566798809504 0.3688888419032221 1.0 1.0 30 P49069,O15372,O00560,P46379,Q92530,Q96HY6,Q9UL15 7 +Regulation of fc receptor mediated stimulatory signaling pathway 0.7640700317195777 0.8964665214542381 0.3700036529665762 1.0 1.0 3 Q06481 1 +Cell migration involved in sprouting angiogenesis 0.5361377143659153 0.8953343967276733 0.3706083582809496 1.0 1.0 8 O14786,P09601,P04083 3 +Natural killer cell activation involved in immune response 0.7629580948288728 0.8924023345378534 0.3721773202623137 1.0 1.0 3 P11279 1 +Positive regulation of leukocyte degranulation 0.7629580948288728 0.8924023345378534 0.3721773202623137 1.0 1.0 3 P11279 1 +Natural killer cell degranulation 0.7629580948288728 0.8924023345378534 0.3721773202623137 1.0 1.0 3 P11279 1 +Chemokine production 0.5299977968542384 0.8882298960114773 0.374417100488623 1.0 1.0 10 P09601 1 +Mitochondrial transcription 0.5360353006772258 0.8873404126295529 0.3748956540902299 1.0 1.0 7 Q9BSK2 1 +Protein o linked glycosylation via serine 0.600693058968464 0.8872223853501292 0.3749591826958101 1.0 1.0 4 Q7Z4H8,Q10472 2 +Synaptic transmission gabaergic 0.5694588146619253 0.88535340862768 0.3759660527589739 1.0 1.0 5 P51790,P21359,Q13641 3 +Hypotonic response 0.7608759717199293 0.8848013403466541 0.3762637864406641 1.0 1.0 3 P30536 1 +Cellular hypotonic response 0.7608759717199293 0.8848013403466541 0.3762637864406641 1.0 1.0 3 P30536 1 +Positive regulation of immune effector process 0.3790699381145502 0.8840513393054785 0.3766684994761977 1.0 1.0 37 P01889,Q15833,Q06481,P09601,P04083,Q9UDY8 6 +Regulation of notch signaling pathway 0.531335536514721 0.8829156281704097 0.37728185907612 1.0 1.0 9 Q9Y6N7,Q86U44,P57105,Q9Y5A9 4 +Neuron projection guidance 0.4505445102799774 0.88189072892998 0.3778359010991026 1.0 1.0 24 Q9Y6N7,P42892,P05067,Q13509,Q15375,P84095,Q04721,O14786 8 +Negative regulation of production of molecular mediator of immune response 0.9153846153846088 0.8798165206968432 0.3789587134432071 1.0 1.0 2 P09601 1 +Positive regulation of rho protein signal transduction 0.598843396301672 0.8796359316817774 0.3790565671274417 1.0 1.0 4 Q9Y6N7 1 +Regulation of tor signaling 0.5140893262597007 0.8791689986740742 0.3793096507839832 1.0 1.0 14 O75844 1 +Motor behavior 0.7588890593383911 0.8775594079827871 0.3801828659409578 1.0 1.0 3 P04062 1 +Synaptic transmission dopaminergic 0.5674712808361806 0.8769367323258845 0.3805210033415929 1.0 1.0 5 P41440 1 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4218729407204792 0.8724902464566323 0.3829409867920863 1.0 1.0 27 P49069,O15372,O00560,P46379,Q92530,Q96HY6,Q9UL15 7 +Inositol phosphate catabolic process 0.5336358017100344 0.8713424272057424 0.3835672111477373 1.0 1.0 6 Q10713 1 +Positive regulation of endothelial cell proliferation 0.5255012511202689 0.8671977752354397 0.3858336550478711 1.0 1.0 10 O14786,P26583,P09601 3 +Neuron projection regeneration 0.5296306149448943 0.8658960279789372 0.3865471815270633 1.0 1.0 8 P30536,Q96G23 2 +Zinc ion homeostasis 0.5951378127932371 0.8644682964982562 0.3873306890202996 1.0 1.0 4 Q8TAD4 1 +Regulation of tube size 0.5247599659494084 0.8637351810841662 0.3877333825812772 1.0 1.0 10 Q9HB40 1 +Positive regulation by symbiont of entry into host 0.9104615384615388 0.8634993626813471 0.3878629696861932 1.0 1.0 2 P19474 1 +Negative regulation of lymphocyte differentiation 0.5948992272134116 0.8634931755155703 0.3878663700174474 1.0 1.0 4 P04083 1 +Insulin receptor signaling pathway 0.4106591115003487 0.8629389771788724 0.3881710190125076 1.0 1.0 28 Q6ZWJ1,P11802,P43490,Q9Y5X3,Q9H1E3,Q92572,Q9UQB8,Q15043 8 +Positive regulation of interleukin 1 production 0.5267532245701418 0.8618588288083989 0.3887652073833412 1.0 1.0 9 P05067 1 +Negative regulation of autophagy of mitochondrion 0.7540757127276739 0.8600636335245561 0.389753966342421 1.0 1.0 3 P30536 1 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.5935762956465052 0.858089504521684 0.3908430423300633 1.0 1.0 4 O75832,P14174 2 +Vitamin metabolic process 0.4292322450026785 0.8580078331097551 0.3908881381209497 1.0 1.0 26 Q9H2D1,Q8N0U8,P04062 3 +Cellular pigmentation 0.5234513874701904 0.8576261152300518 0.3910989498521791 1.0 1.0 10 Q9BXS5,Q15907,Q9H0F7 3 +Organic anion transport 0.3998678717747199 0.8562562470307498 0.3918560566637032 1.0 1.0 50 Q8TB61,Q9UBX3,Q86VD7,Q9H2D1,P33527,P41440,P04083,P07602,Q9Y619 9 +Gliogenesis 0.4051466708013351 0.8547837054579583 0.3926709005596507 1.0 1.0 53 Q96G23,Q9UI10,P30536,P49770,P05067,Q96N66,Q92542,P04062,P04083,O75306,Q8IXJ6 11 +Positive regulation of stress activated protein kinase signaling cascade 0.5091103881970029 0.854098127395381 0.3930506214074096 1.0 1.0 14 O00560 1 +Cellular response to nutrient 0.5288938868033859 0.8506004198076177 0.3949913561696929 1.0 1.0 6 P09601 1 +Erk1 and erk2 cascade 0.3765602819788253 0.8472508158134011 0.3968553348762045 1.0 1.0 38 Q96P70,P05067,Q15375,P57105,Q13641,O14786 6 +Regulation of cellular carbohydrate catabolic process 0.528100373620866 0.8471349163453497 0.3969199251559832 1.0 1.0 6 Q14108 1 +Folate transmembrane transport 0.904923076923067 0.8452255447879027 0.3979849224659646 1.0 1.0 2 Q9H2D1 1 +Folic acid transport 0.904923076923067 0.8452255447879027 0.3979849224659646 1.0 1.0 2 Q9H2D1 1 +Insulin secretion involved in cellular response to glucose stimulus 0.5247017888006142 0.8436658080730429 0.3988561791915619 1.0 1.0 8 Q6ZWJ1,P30626,Q8N183 3 +Organic hydroxy compound transport 0.4176926717643837 0.8430975252074207 0.3991739027282843 1.0 1.0 27 P30536,O15118,Q8WTV0 3 +Myeloid leukocyte differentiation 0.3757722891689946 0.8400401225733423 0.400885890669773 1.0 1.0 31 P05067,Q15904,Q14739,P04062,Q16539 5 +Notch signaling pathway 0.4733894067217223 0.8371311635904323 0.4025188450569406 1.0 1.0 20 Q9NVX2,Q9Y6N7,Q9UBV2,P05067,P57105,Q92542 6 +Developmental induction 0.7475132513136686 0.8363247953153614 0.4029722076985331 1.0 1.0 3 Q9Y6N7 1 +Response to epidermal growth factor 0.5053739218130162 0.8353286528485768 0.4035326889346147 1.0 1.0 14 Q96A49,Q9UQB8,O95429 3 +Regulation of immune effector process 0.3880903285160427 0.8348250110540458 0.4038162414305222 1.0 1.0 45 P46108,P01889,Q15833,Q06481,P09601,P04083,P11279,Q9UDY8 8 +Interleukin 12 production 0.5251007179511169 0.834049494045346 0.4042530940095674 1.0 1.0 6 Q16539,P01889 2 +Regulation of cation channel activity 0.5049488674821518 0.8331960894139289 0.4047341477336794 1.0 1.0 14 P05067,P0DP25,P27105 3 +Cerebellar purkinje cell layer development 0.5236379039902691 0.832281043589047 0.4052503279817501 1.0 1.0 7 P04062 1 +Maintenance of location in cell 0.3855674103524221 0.8292285373360244 0.4069750997640495 1.0 1.0 44 P30536,P24390,Q9UH99,O43731,P10253,P0DP25,P02792 7 +Regulation of endocytosis 0.3947330742442401 0.8290803227460648 0.407058957460169 1.0 1.0 49 Q8N6T3,O75955,P05067,P50897,O00560,Q06481,P57105,P41440,P0DP25 9 +Negative regulation of growth 0.3630528092893004 0.8289815614870844 0.4071148408898322 1.0 1.0 32 Q9P0J0,P06400,Q7Z5J4,P63244,Q15375,P50897,Q8IWE4,P11413,P30153,O14786,O94813,Q8N0X7 12 +Regulation of inflammatory response to antigenic stimulus 0.5225730290262154 0.8275703482157644 0.4079138666470769 1.0 1.0 7 Q16539 1 +Embryonic heart tube morphogenesis 0.7446448111335946 0.8259922250243988 0.4088085022904093 1.0 1.0 3 Q9Y366 1 +Regulation of erad pathway 0.5229522954582468 0.8246924854381297 0.4095461990375164 1.0 1.0 6 P46379 1 +Interleukin 1 production 0.5135084994998149 0.8237223624670874 0.4100973300392923 1.0 1.0 11 P05067,Q9UDY8 2 +Jnk cascade 0.4830899163508685 0.822191052741459 0.4109681701781675 1.0 1.0 18 Q969S3,P05067,O00560 3 +Calcium ion import 0.5062528416441976 0.8202839882589024 0.4120542320641496 1.0 1.0 13 P21796 1 +T cell mediated immunity 0.5092418263552093 0.8179704051657745 0.4133740863448916 1.0 1.0 12 P04439,Q9BY67,P01889,P53634,Q9UDY8 5 +Protein mannosylation 0.5836435089509587 0.8177045241230425 0.4135259265351791 1.0 1.0 4 Q6ZXV5 1 +Protein o linked mannosylation 0.5836435089509587 0.8177045241230425 0.4135259265351791 1.0 1.0 4 Q6ZXV5 1 +Mitochondrial protein processing 0.5203119232511998 0.8175786505471083 0.4135978223318397 1.0 1.0 7 Q10713 1 +Membrane fusion 0.3710667280825832 0.8170192528999802 0.4139174255967575 1.0 1.0 37 O60499,O15498,Q9UQN3,P04083,Q13190 5 +Embryonic digit morphogenesis 0.5187525529025125 0.8169208686677351 0.4139736510273906 1.0 1.0 8 P42892 1 +Vacuolar localization 0.5055244658115716 0.8167086156789827 0.4140949665033029 1.0 1.0 13 Q15833,Q86YV9,P09601 3 +Regulation of generation of precursor metabolites and energy 0.3706834396924255 0.8138173150524424 0.415749614216196 1.0 1.0 37 P14406,Q9BSK2,P05067 3 +Vascular process in circulatory system 0.4037814856576573 0.8130097710444301 0.4162124560549909 1.0 1.0 28 P42892,Q9HB40,P33527 3 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.5043077227714461 0.8107398344698106 0.4175150923326143 1.0 1.0 13 O95881 1 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.894153846153839 0.809960004502009 0.4179631630398321 1.0 1.0 2 P42892 1 +Axonogenesis involved in innervation 0.894153846153839 0.809960004502009 0.4179631630398321 1.0 1.0 2 P42892 1 +Phosphatidylserine metabolic process 0.5815982097460299 0.8094321049824259 0.4182666415358285 1.0 1.0 4 Q8NCC3 1 +Carbohydrate transmembrane transport 0.505290128771965 0.7989682220710012 0.4243088385458229 1.0 1.0 12 Q16539,P52789,Q06481 3 +Double strand break repair via break induced replication 0.5156428575733673 0.7969949507734616 0.4254539637789856 1.0 1.0 7 P33993,Q9BRT9 2 +Anatomical structure maturation 0.3648732735277248 0.7966392463932186 0.4256605772782071 1.0 1.0 35 Q9Y2W6,P05067,P06400,P11413,O75503,Q12768,O95696,P04818,P21359,P30153,P04062,Q15645,Q8IXJ6 13 +Regulation of synaptic transmission dopaminergic 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Positive regulation of heterotypic cell cell adhesion 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Cell adhesion molecule production 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Positive regulation of cell adhesion molecule production 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Positive regulation of toll like receptor 3 signaling pathway 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Regulation of mitochondrial membrane permeability 0.5006713355120879 0.7929310865671628 0.4278179743932393 1.0 1.0 13 P45880 1 +Regulation of high voltage gated calcium channel activity 0.888307692307686 0.7909726029839023 0.428959979082419 1.0 1.0 2 P0DP25 1 +Sequestering of iron ion 0.8883076923076861 0.7909726029839012 0.4289599790824197 1.0 1.0 2 P02792 1 +Transition metal ion transport 0.4873238040781999 0.7887196741421344 0.4302758663728767 1.0 1.0 16 O15173,Q15907,Q9HD20,Q8TAD4,Q9HC07,P02792,Q15043 7 +Plasma membrane raft organization 0.7342010985749685 0.7886119436299256 0.4303388480987982 1.0 1.0 3 P41440 1 +Plasma membrane raft assembly 0.7342010985749685 0.7886119436299256 0.4303388480987982 1.0 1.0 3 P41440 1 +Positive regulation of inflammatory response 0.502626921368421 0.7861917339398248 0.4317551680329798 1.0 1.0 12 P05067,P33527,Q08722,P53634 4 +Oocyte maturation 0.5123950617821674 0.7827179710354037 0.43379274667577 1.0 1.0 7 Q12768,Q15645,P30153,Q8IXJ6 4 +Response to mitochondrial depolarisation 0.5110650613733778 0.7825208533967086 0.4339085348891633 1.0 1.0 8 P52789,Q16543,P04062 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5110650613733778 0.7825208533967086 0.4339085348891633 1.0 1.0 8 P52789,Q16543,P04062 3 +Regulation of epidermal growth factor activated receptor activity 0.5745183166549337 0.7809210587502149 0.4348489255008991 1.0 1.0 4 P05067 1 +Protein containing complex remodeling 0.8846153846153736 0.779040516046276 0.4359558483778532 1.0 1.0 2 Q8WTV0 1 +Regulation of voltage gated calcium channel activity 0.5734095922612323 0.7764744099714973 0.4374689245932535 1.0 1.0 4 P0DP25 1 +Regulation of gastrulation 0.5433307428127757 0.7756546355739374 0.4379529317735562 1.0 1.0 5 P63244,Q8NBL1 2 +Amyloid precursor protein metabolic process 0.4683371975699316 0.7730641266298631 0.43948443027648 1.0 1.0 19 Q15392,Q96P70,Q92542 3 +Organelle membrane fusion 0.4165921851785856 0.7722794629560685 0.4399489262875933 1.0 1.0 26 O60499,Q9UQN3,Q9UN37,Q9UNK0,P51809,P04083,Q13190 7 +Camera type eye morphogenesis 0.5040993188593647 0.7678675089313187 0.4425659021790562 1.0 1.0 10 P54802,Q14517,Q99622,Q04721,Q15555 5 +Lipid storage 0.4673478477971511 0.7675653364514656 0.4427454627103266 1.0 1.0 19 P17900,Q9H6V9,P04062,Q8WTV0 4 +Regulation of phosphatidylinositol 3 kinase signaling 0.5081065666573974 0.7639214138711352 0.4449140754954084 1.0 1.0 7 Q10713 1 +Regulation of atp biosynthetic process 0.5088707762091031 0.7637125811338483 0.4450385416807401 1.0 1.0 6 P00403 1 +Maintenance of protein location in mitochondrion 0.7269399789131876 0.7628596464656793 0.4455471044982801 1.0 1.0 3 P30536 1 +Phosphatidylinositol dephosphorylation 0.5084660939409822 0.7619699397409391 0.4460779454024406 1.0 1.0 6 Q10713 1 +Negative regulation of mrna 3 end processing 0.5083179297596918 0.7613320641476474 0.4464587535830371 1.0 1.0 6 O75150,P18615,O00267,Q5VTR2,Q6PJT7 5 +Exocytic process 0.489842943389056 0.7578063900299425 0.4485668964032685 1.0 1.0 14 O15498,Q7L0J3,Q15833,P51809,Q7Z6M1 5 +Response to ph 0.5073940982185929 0.757356599187352 0.4488362503936163 1.0 1.0 6 P04062 1 +Regulation of carbohydrate catabolic process 0.4896412241921954 0.7568054934321763 0.4491664011905587 1.0 1.0 14 Q14108 1 +Foam cell differentiation 0.7251461988304116 0.7565296215131577 0.4493317194475281 1.0 1.0 3 P35610,P42224 2 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.7245306248076355 0.7543603288028291 0.4506328859639166 1.0 1.0 3 O95817,Q8IXJ6 2 +Positive regulation of smooth muscle cell proliferation 0.5045024631312652 0.7533144815722289 0.4512609585821145 1.0 1.0 8 P09601 1 +Isoprenoid metabolic process 0.4047304900794642 0.7524604994883639 0.4517741757382876 1.0 1.0 27 P61916,Q9HB40,P51648,P37268,Q6NUM9 5 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.5673778406980211 0.7523751678366356 0.4518254755867552 1.0 1.0 4 P30536 1 +Glucose import 0.5025164901874579 0.7514878264850089 0.4523591243583829 1.0 1.0 9 P52789,Q06481 2 +Positive regulation of mitochondrial depolarization 0.7233728660350158 0.7502845536749726 0.4530833435162678 1.0 1.0 3 P30536 1 +Phosphatidylcholine acyl chain remodeling 0.7232994767620831 0.7500263792282218 0.4532388173648023 1.0 1.0 3 Q8NF37,Q96N66 2 +Positive regulation of endothelial cell migration 0.469601447151991 0.7488423201866746 0.4539522488313838 1.0 1.0 18 Q16539,P04083,P09601,Q8WTV0 4 +Protein localization to mitochondrion 0.3990998869885802 0.7473549821019025 0.4548493118296437 1.0 1.0 57 Q9Y3D6,O95429,Q10713,P30536,Q99797,P55786,Q9NS69,O14925,Q9P0J0,P52789,Q99595,Q8N4H5,P0DP25,Q9Y584,O14737 15 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.4965548398866776 0.7440137512089353 0.4568681559367684 1.0 1.0 11 O43657 1 +Regulation of glycolytic process 0.5004936001884788 0.7423677836707366 0.4578645332334976 1.0 1.0 9 P05067,P54619,P54646,Q9NQ88,P56537 5 +Neuron projection organization 0.4430198902548706 0.7391820613335859 0.4597964521580557 1.0 1.0 22 Q05086,Q9UQB8,P05067 3 +Protein ufmylation 0.5635076454299626 0.736997473775585 0.4611238856258279 1.0 1.0 4 Q9GZZ9,Q96HY6 2 +Substantia nigra development 0.4770438064510156 0.7354718339742503 0.4620521875350363 1.0 1.0 16 P24539,P11413,O15027,P0DP25,P00367,Q8IXJ6 6 +Insulin secretion 0.4018738673010848 0.7326117526446638 0.4637952609304996 1.0 1.0 27 O43768,Q15907,Q6ZWJ1,Q8N183,Q8NE86,P30626,P40939,P04083,P00367 9 +3 utr mediated mrna stabilization 0.4997892770810691 0.7324397402071997 0.4639002103428826 1.0 1.0 8 P98175,Q16539,P16989 3 +Prostanoid biosynthetic process 0.5010796814408497 0.7302709603121557 0.4652245751863675 1.0 1.0 6 Q8NCG7,P04083 2 +Negative regulation of atp metabolic process 0.4969248926180215 0.726319222943589 0.4676430976316905 1.0 1.0 9 P30536,Q9Y3D6 2 +Negative regulation of dna binding 0.4982854433769588 0.7257982506528827 0.4679624595030685 1.0 1.0 8 P09601 1 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.4990461194597608 0.7244355490592298 0.468798381936391 1.0 1.0 7 Q6ZWJ1,Q8N183 2 +Error prone translesion synthesis 0.715267373994597 0.7219076703176509 0.4703512451178921 1.0 1.0 3 P56282 1 +Positive regulation of response to endoplasmic reticulum stress 0.4990486488650817 0.721592603540229 0.470544987940602 1.0 1.0 6 P46379 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.86646153846153 0.7210994845130865 0.4708483081863868 1.0 1.0 2 Q92542 1 +Microtubule anchoring 0.4888484815495229 0.7205268515508575 0.4712006732624663 1.0 1.0 12 Q8TD16,Q9Y496,Q9P287 3 +Cellular response to estradiol stimulus 0.5591812702832694 0.7198906330504977 0.4715923357161729 1.0 1.0 4 O95831,Q8NI77 2 +Neurotransmitter metabolic process 0.5585124784061279 0.7172543055797503 0.4732171965145342 1.0 1.0 4 Q8NCG7 1 +Post golgi vesicle mediated transport 0.3663361488086486 0.7162493793514833 0.4738373775562268 1.0 1.0 41 Q8IYI6,Q4J6C6,Q92538,Q92572,P63244,P50570,O15127,Q8N2H4,O15126,Q709C8,P11279 11 +Suppression of viral release by host 0.497732795953583 0.7159793200627292 0.4740041183190364 1.0 1.0 6 P19474 1 +Zinc ion transport 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +Protein localization to golgi apparatus 0.487648349121601 0.7148456388244621 0.4747044306783547 1.0 1.0 12 Q8TD16,Q8N2H4,Q92538,Q709C8 4 +Somatic diversification of immune receptors via somatic mutation 0.4966094256909014 0.7138732065847692 0.4753055865966415 1.0 1.0 7 Q9UQ84 1 +Autonomic nervous system development 0.7123864920960168 0.7118907766782135 0.4765324140335725 1.0 1.0 3 O14786 1 +Sympathetic nervous system development 0.7123864920960168 0.7118907766782135 0.4765324140335725 1.0 1.0 3 O14786 1 +Positive regulation of t cell mediated immunity 0.4960197902516102 0.7113211615123514 0.4768852411205242 1.0 1.0 7 P04439,Q9UDY8,P01889 3 +Multi multicellular organism process 0.4158366262319448 0.7112626161825145 0.4769215129682234 1.0 1.0 25 Q9UIQ6,Q9BQE5,P41440 3 +Phosphatidylcholine metabolic process 0.4801391511419387 0.709860845089751 0.4777904332649156 1.0 1.0 14 P35790,Q8NCC3,Q8WTV0 3 +Regulation of dna binding 0.3892203677613484 0.7081395188121985 0.4788586205035465 1.0 1.0 28 P30626,O75844,P09601,P0DP25,Q8IXJ6 5 +Positive regulation of glycoprotein metabolic process 0.4941432124967071 0.7075547598088503 0.4792217954470499 1.0 1.0 8 Q9H0U4,P35610,Q92542 3 +Nuclear membrane reassembly 0.483007589885675 0.7071574994957669 0.4794686067436484 1.0 1.0 13 Q86XL3,Q8IXJ6 2 +Protein maturation 0.4201990961811287 0.7071337505735127 0.4794833637552185 1.0 1.0 72 Q86UY6,P49366,Q10713,Q99797,P42892,Q14CX7,Q8TAD4,Q9UBS4,O75503,Q9BXS4,O75844,Q15392,Q9UMS0,Q9BXJ9,Q92542,Q92896 16 +Regeneration 0.3794924880947308 0.7066727752917609 0.4797698518422226 1.0 1.0 29 P11717,Q96G23,P00374,P62841,P30536,P58107,P04818,P09601,P12004,Q7Z4V5,P50416,P04083,P06493 13 +Amine metabolic process 0.47512804149398 0.7039523481382257 0.4814624496232267 1.0 1.0 15 Q6QHF9,P19623 2 +Positive regulation of synaptic transmission 0.4749822466889319 0.703221011854629 0.4819180266992151 1.0 1.0 15 P41440,P05067,Q92542 3 +Development of primary female sexual characteristics 0.4811120652645952 0.6980358298795643 0.4851547870001933 1.0 1.0 13 O75874,Q05086,Q9UI10,O95470 4 +Positive regulation of cyclic nucleotide phosphodiesterase activity 0.8584615384615288 0.6959780545779986 0.4864425732598199 1.0 1.0 2 P0DP25 1 +Reactive nitrogen species metabolic process 0.4646924555570712 0.695554453140412 0.4867078984777322 1.0 1.0 17 P06280,Q92945,P35270,P16435,P08238,P30536,P50570,O43169,Q08722 9 +Negative regulation of ubiquitin dependent protein catabolic process 0.4211652799793991 0.6950357821531823 0.4870328775338124 1.0 1.0 24 P49069,O15372,O00560,P46379,Q96HY6,Q9UL15 6 +Translesion synthesis 0.4901890284411202 0.6902115216611793 0.4900611788432953 1.0 1.0 8 P56282,Q15054 2 +Metencephalon development 0.3865309071304668 0.6889280756611784 0.4908685304623446 1.0 1.0 28 P54802,P04062,P46108,Q92542 4 +Phosphatidylethanolamine metabolic process 0.5511030105832773 0.6881993785176667 0.4913272352492139 1.0 1.0 4 P35790 1 +Multicellular organism growth 0.346142850624581 0.6873516437971631 0.4918611620818076 1.0 1.0 32 O75844,Q9HCL2,O95470 3 +Embryonic pattern specification 0.4909694478231595 0.6872475006861919 0.4919267757687351 1.0 1.0 6 O14786 1 +Regulation of glial cell migration 0.8553846153846179 0.6863878945755912 0.4924685360562228 1.0 1.0 2 Q96G23 1 +Diapedesis 0.8553846153846041 0.686387894575549 0.4924685360562495 1.0 1.0 2 P46108 1 +Interleukin 6 production 0.4753476270313579 0.6863527261105914 0.492490707526644 1.0 1.0 14 P05067,P04062 2 +Regulation of lipid localization 0.4118876866252516 0.685688333123716 0.4929096654009415 1.0 1.0 25 P30536,Q9H4M9,O15260,Q8WTV0 4 +Establishment of protein localization to plasma membrane 0.434004901658568 0.6855389148762985 0.4930039129696122 1.0 1.0 22 Q4J6C6,P63244,Q15904,Q8N2H4,Q9H8Y8 5 +Regulation of lipid metabolic process 0.3824313641028314 0.6849258287049641 0.493390726381357 1.0 1.0 52 O75874,P61916,Q13510,P30536,Q8NCG7,O75844,Q9H6K4,Q8WTV0,P07602,P04083 10 +Regulation of receptor mediated endocytosis 0.4263935414349055 0.6816522462006454 0.4954588700101792 1.0 1.0 23 P50897,O00560,P41440,P05067 4 +Golgi to endosome transport 0.4891089372743384 0.6815271884483475 0.4955379691519361 1.0 1.0 7 Q8N2H4,Q709C8 2 +Inclusion body assembly 0.4848829003073124 0.6801276419745002 0.4964236433270486 1.0 1.0 10 P62333,P25685,P49427,O95817,P54652,Q9UL15 6 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4886448599310236 0.6795345186364253 0.4967992437442059 1.0 1.0 7 O95881 1 +Negative regulation of cell growth 0.3852114137512675 0.679523884773435 0.4968059791106025 1.0 1.0 28 Q9P0J0,P06400,Q15375,P50897,Q8IWE4,O14786 6 +Peripheral nervous system development 0.4845002679833756 0.6783979174170118 0.4975194292008065 1.0 1.0 10 P51648 1 +Protein localization to cilium 0.4737097547673888 0.6783446200708045 0.4975532136765133 1.0 1.0 14 Q9H4M9,Q10713,Q9H0F7 3 +Exonucleolytic catabolism of deadenylated mrna 0.4843401561570953 0.6776743388234739 0.4979782002627249 1.0 1.0 10 Q969T7,Q9NQT5 2 +Regulation of cellular respiration 0.4560841437845405 0.6761919262558842 0.4989187979564473 1.0 1.0 18 P14406,Q9BSK2 2 +Detection of other organism 0.8516923076922992 0.6749342908330294 0.4997175131615239 1.0 1.0 2 P01889 1 +Protection from natural killer cell mediated cytotoxicity 0.8516923076922992 0.6749342908330294 0.4997175131615239 1.0 1.0 2 P01889 1 +Cellular carbohydrate metabolic process 0.3969017394575617 0.6733539984624924 0.5007221069821868 1.0 1.0 61 O75874,Q93063,Q10713,P16278,Q9NUJ1,Q9BYT8,P48735,P46020,Q14108,P52789,O75844,P10253,Q9NQ88,P29218,Q5MIZ7,Q15118,Q8N6G5,O43505 18 +Outflow tract septum morphogenesis 0.8501538461538483 0.670179869430021 0.502743134965224 1.0 1.0 2 O14786 1 +Axon choice point recognition 0.8501538461538329 0.6701798694299743 0.5027431349652538 1.0 1.0 2 P05067 1 +Axon midline choice point recognition 0.8501538461538329 0.6701798694299743 0.5027431349652538 1.0 1.0 2 P05067 1 +Heparan sulfate proteoglycan biosynthetic process 0.5171801243250453 0.6684984797914476 0.5038154519721181 1.0 1.0 5 O94766,Q93063 2 +Heparan sulfate proteoglycan metabolic process 0.5171801243250453 0.6684984797914476 0.5038154519721181 1.0 1.0 5 O94766,Q93063 2 +Erythrocyte maturation 0.6989843028624219 0.6658009996052514 0.5055383058797249 1.0 1.0 3 O95696,P11413 2 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4841046552064498 0.6636725119101794 0.5068999362589537 1.0 1.0 8 O95881 1 +Positive regulation of mitochondrial membrane potential 0.544642857142849 0.6631080867159754 0.5072613318408843 1.0 1.0 4 P31751,Q8IWA4,P55072 3 +Myeloid leukocyte mediated immunity 0.4735231822415578 0.6617032350415859 0.5081614310393676 1.0 1.0 13 P09601 1 +Regulation of collateral sprouting 0.6977531548168694 0.6616113315321102 0.5082203435035053 1.0 1.0 3 Q8N0X7,Q15375 2 +Positive regulation of metaphase anaphase transition of cell cycle 0.4823142361492555 0.6612169669015053 0.5084731818265311 1.0 1.0 9 P06400,Q13042,P30260 3 +Male meiosis i 0.6974453678054813 0.6605651254747269 0.5088912403670478 1.0 1.0 3 Q15645,Q8IWV8 2 +Regulation of axon guidance 0.5431701164190259 0.6574211519954932 0.5109101546335446 1.0 1.0 4 O14786 1 +Organelle fusion 0.3608627813302048 0.6565513125757273 0.5114694634663786 1.0 1.0 42 O60499,Q9Y3D6,Q9NX63,Q99536,O60313,Q9UQN3,Q9UN37,P51809,Q9UNK0,Q9NQG6,Q9P253,P04083,Q13190,P06493 14 +Regulation of phagocytosis 0.4614220928096618 0.6555374559474686 0.5121217789319434 1.0 1.0 16 P50570,Q06481,P63244,Q8WTV0 4 +Phosphate ion transmembrane transport 0.6953782882846095 0.6535515404087673 0.5134007735820982 1.0 1.0 3 Q9UBX3 1 +Phosphate ion transport 0.6953782882846095 0.6535515404087673 0.5134007735820982 1.0 1.0 3 Q9UBX3 1 +Positive regulation of smoothened signaling pathway 0.4829347920380771 0.6533964976651921 0.5135006961279014 1.0 1.0 6 Q6PHR2 1 +Glycolipid biosynthetic process 0.4824626691377086 0.6530922622999844 0.513696800330655 1.0 1.0 7 Q8NBX0 1 +Cellular response to mechanical stimulus 0.4823270657522928 0.652514480081938 0.5140693347859351 1.0 1.0 7 O95817,P49327,Q9Y624 3 +Trna methylation 0.4710088121301705 0.6497356302500461 0.5158630045269517 1.0 1.0 13 Q9UET6,Q9UJA5,O75648 3 +Amyloid precursor protein catabolic process 0.4600924558058383 0.6487980280957146 0.5164689322044975 1.0 1.0 16 Q15392,Q96P70 2 +Smooth muscle cell migration 0.4773682285181705 0.6462983365138532 0.518086164985788 1.0 1.0 10 O14786,P46108 2 +Regulation of neuronal synaptic plasticity 0.4800003797332973 0.6458782232734691 0.5183582237003228 1.0 1.0 8 Q96A49,P05067 2 +Ornithine transport 0.8421538461538305 0.6456319033001449 0.5185177709700621 1.0 1.0 2 Q9Y619 1 +Carbohydrate homeostasis 0.3555937279769308 0.6434056557015055 0.5199609145488353 1.0 1.0 40 Q6ZWJ1,Q15907,P49366,Q8N183,Q8NE86,Q9H1E3,P30626,P63244,P52789,P42785,Q06481,Q15043 12 +Receptor recycling 0.4793221028422761 0.6429463166597238 0.5202589342388242 1.0 1.0 8 P42892,Q15907 2 +Regulation of lymphocyte mediated immunity 0.4198839928589324 0.6421856040833059 0.5207526790074852 1.0 1.0 23 P04439,P46108,P01889,Q96FV9,P11279,Q9UDY8,Q9NQT5 7 +Regulation of pattern recognition receptor signaling pathway 0.4327986522228987 0.6409301739092376 0.5215680505642841 1.0 1.0 21 Q06481,Q9NUD5,O43657,P41440 4 +Protein hydroxylation 0.4655073442095296 0.6384693043274791 0.5231682294013589 1.0 1.0 14 O75718,O15460,Q32P28 3 +Regulation of vasculature development 0.3512917248183774 0.6382176042482481 0.5233320391491381 1.0 1.0 38 P42224,P52789,Q4VCS5,Q9NZ08,P09601,P57105,O14786 7 +Alcohol metabolic process 0.434726412063944 0.6376694705880792 0.5236888628497887 1.0 1.0 86 P35270,O15118,P00374,Q16850,Q9BQE5,Q13510,P48735,P51648,P35610,P37268,P29218,Q14739,Q8WTV0,O75874,P61916,P04035,Q6NUM9,P04062,Q9BW91,Q10713,P05067,Q15392 22 +Cell activation involved in immune response 0.3489814957428054 0.6343615264916576 0.5258449118845183 1.0 1.0 37 P05067,Q9UQ84,Q15833,Q96FV9,P09601,P04083,P11279,Q9UDY8,Q9NQT5,P13051 10 +Macropinocytosis 0.8378461538461438 0.6325391746373035 0.527034618560227 1.0 1.0 2 Q06481 1 +Regulation of inclusion body assembly 0.4768510407891783 0.6322867571285062 0.5271995153997828 1.0 1.0 8 P62333,P25685,P49427,P54652,Q9UL15 5 +Positive regulation of peptidyl serine phosphorylation 0.4606877972973266 0.6320921998303682 0.5273266318490497 1.0 1.0 15 O95429,P35080,P07900,P05067,P08238,Q92600,P14174,Q13043 8 +Reactive oxygen species metabolic process 0.3559514162192347 0.6314810920608581 0.5277260084288491 1.0 1.0 41 P51790,Q9BSK2,P00374,P00403,P30536,Q15067,Q9P0J0,Q92538,P52789,P42785,Q9NQ88,Q16539,Q8IXJ6 13 +Regulation of hormone levels 0.4001257233192239 0.6303394048183216 0.5284725469577656 1.0 1.0 66 O43768,P30536,P42892,Q9HB40,Q53GQ0,Q8NE86,Q8N183,Q16836,Q8TAD4,Q15043,Q15907,O75844,Q6NUM9,P04083,O95470,Q6ZWJ1,P30626,P40939,P00367 19 +Midbrain development 0.4423299364519318 0.6302340160781983 0.5285414867659579 1.0 1.0 19 P24539,P11413,O15027,P0DP25,P00367,Q8IXJ6 6 +Negative regulation of sprouting angiogenesis 0.8366153846153683 0.6288150015441432 0.5294701776683612 1.0 1.0 2 P57105 1 +Extracellular matrix assembly 0.535696321504478 0.6287618857696116 0.5295049560212615 1.0 1.0 4 Q96AY3 1 +Regulation of platelet activation 0.8363076923076813 0.6278851261082922 0.5300791953866935 1.0 1.0 2 Q9BWH2 1 +Negative regulation of vasculature development 0.4595917814109972 0.6266895773072844 0.5308627372621899 1.0 1.0 15 Q4VCS5,P57105,P42224 3 +Positive regulation of protein autophosphorylation 0.4759332442049998 0.6253858553476863 0.5317178433082654 1.0 1.0 7 P0DP25 1 +Positive regulation of regulated secretory pathway 0.5343044337767383 0.6234628411183415 0.532980413573376 1.0 1.0 4 P11279 1 +T cell proliferation 0.4020019304187672 0.6221858763145298 0.5338196519691762 1.0 1.0 25 P30825,P49366,P04439,Q96EY1,Q9HCL2,Q9BY67,P10644,Q92542,P04083,Q9UDY8 10 +Regulation of receptor internalization 0.4716579224152552 0.6208038903699042 0.534728663234745 1.0 1.0 10 O00560,P41440 2 +Epidermis development 0.3582240243499183 0.6204617143914559 0.5349538525091715 1.0 1.0 43 Q13510,P67809,O75844,P51648,P04083 5 +Regulation of ryanodine sensitive calcium release channel activity 0.5050728366408893 0.6200648609634952 0.5352150854188713 1.0 1.0 5 P0DP25 1 +Renal system vasculature development 0.684210526315792 0.6160551008719591 0.5378581539783731 1.0 1.0 3 O14786,Q04721 2 +Rho protein signal transduction 0.393074578818869 0.6153495788988582 0.5383238820213694 1.0 1.0 26 P52565,Q9Y6N7,O75955,P84095,P57105,Q9Y624,P41440,O14786 8 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.373608525861194 0.6143465092730336 0.538986374871633 1.0 1.0 52 P53350,O75832,Q9NRR5,P54725,P49069,P63244,P54727,O15372,O00560,P46379,P04062,Q96HY6,Q8IXJ6,Q9UL15 14 +Plasma membrane organization 0.400540509435176 0.612868630645006 0.5399632066395785 1.0 1.0 25 Q9UQB8,Q9UQN3,P41440,Q96CP7 4 +Receptor metabolic process 0.3370933877982306 0.6126508696703808 0.5401072147189852 1.0 1.0 32 Q15907,P42892,O75955,P50570,O00560,P41440 6 +Long chain fatty acid transport 0.4631560709618205 0.6126056016816844 0.540137153423274 1.0 1.0 13 O43772,P23786,P04083 3 +Cellular response to reactive nitrogen species 0.472746699898779 0.6119527734865513 0.5405690040376006 1.0 1.0 7 O95831,P50570,Q99707,P46108 4 +Response to nitric oxide 0.472746699898779 0.6119527734865513 0.5405690040376006 1.0 1.0 7 O95831,P50570,Q99707,P46108 4 +Actin modification 0.6826693742318541 0.6109350926867485 0.5412425514365524 1.0 1.0 3 Q86TU7 1 +Regulation of t cell mediated immunity 0.4708594795873622 0.6065886055851241 0.5441239639023254 1.0 1.0 8 P04439,Q9UDY8,P01889 3 +Regulation of histone ubiquitination 0.4682442796429276 0.6056576543191488 0.5447421088234665 1.0 1.0 10 Q96FW1 1 +Regulation of inflammatory response 0.3397568129739715 0.6041776043303334 0.5457255689186975 1.0 1.0 34 P28070,Q8NCG7,P05067,P06400,P53634,Q8N2K0,P33527,P04062,P04083,Q16539,P60900 11 +Response to metal ion 0.3828538541253245 0.6038029668740945 0.5459746467158577 1.0 1.0 58 O15118,P30536,P05067,Q8TAD4,P09960,P0DP25,P09601,O60888 8 +Negative regulation of endocytosis 0.4634582154730623 0.6019557746761681 0.5472035763130612 1.0 1.0 12 O00560 1 +Neuron recognition 0.4695045511312611 0.6008075597076876 0.5479681683997468 1.0 1.0 8 O14786,P05067 2 +Golgi to plasma membrane protein transport 0.4540648964794658 0.5995693064023746 0.5487933079878333 1.0 1.0 15 Q8N2H4,P63244,Q4J6C6 3 +Negative regulation of response to biotic stimulus 0.39063911475206 0.5993586257476418 0.5489337610878282 1.0 1.0 26 O43657,P46108,Q8IXJ6,P01889 4 +Establishment or maintenance of monopolar cell polarity 0.4680412171734708 0.5987159155242533 0.5493623420955527 1.0 1.0 9 Q14517 1 +Purine nucleoside diphosphate catabolic process 0.8264615384615264 0.598381823071099 0.5495851914562044 1.0 1.0 2 Q9BW91 1 +Locomotory exploration behavior 0.8252307692307712 0.5947292034455874 0.5520244976812441 1.0 1.0 2 Q05086 1 +Proteasome assembly 0.4687041532779582 0.5942963454205975 0.5523139225406155 1.0 1.0 6 O95456,O75832,Q5VYK3 3 +Retinal rod cell development 0.8246153846153682 0.5929059064522179 0.553244124969275 1.0 1.0 2 P54802 1 +Retinal rod cell differentiation 0.8246153846153682 0.5929059064522179 0.553244124969275 1.0 1.0 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.8246153846153682 0.5929059064522179 0.553244124969275 1.0 1.0 2 P54802 1 +Tor signaling 0.4399082310399662 0.5907297806803562 0.5547014906330541 1.0 1.0 18 O75844,Q96A49,P04062 3 +Response to interleukin 12 0.8233846153846094 0.589265376090421 0.5556832674744498 1.0 1.0 2 P07237 1 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.823384615384604 0.5892653760904054 0.5556832674744603 1.0 1.0 2 Q06481 1 +Regulation of membrane permeability 0.4481265787748245 0.5886776866515491 0.5560775089283525 1.0 1.0 16 P45880 1 +Positive regulation of membrane potential 0.4970742223591158 0.5885562380230321 0.5561589976841936 1.0 1.0 5 Q9UJZ1,Q8IWA4,P55072,P31751 4 +Regulation of cell communication by electrical coupling 0.5238052819356496 0.58390527265888 0.5592840455801809 1.0 1.0 4 P0DP25 1 +Negative regulation of lipase activity 0.8212307692307566 0.5829140608987584 0.5599511545432396 1.0 1.0 2 P04083 1 +Protein transport along microtubule 0.6740619485608379 0.5825961902189174 0.5601651706996238 1.0 1.0 3 O95817 1 +Positive regulation of vasculature development 0.4281339527281493 0.5822708885282084 0.5603842310493539 1.0 1.0 20 P52789,Q9NZ08,P09601 3 +Rna stabilization 0.3712578332741064 0.5810705539722048 0.5611929033657148 1.0 1.0 28 Q96HR8,P98175,P67809,Q14011,Q92804,Q16539,P35637 7 +Cell communication by electrical coupling involved in cardiac conduction 0.495053458321177 0.5806626238399135 0.5614678567471008 1.0 1.0 5 P0DP25 1 +Regulation of dna ligation 0.672822406894432 0.5785520411787655 0.5628914729357894 1.0 1.0 3 Q9UBB9,P18887 2 +Tolerance induction 0.672822406894432 0.5785520411787655 0.5628914729357894 1.0 1.0 3 Q96J02,P01889 2 +Regulation of tolerance induction 0.672822406894432 0.5785520411787655 0.5628914729357894 1.0 1.0 3 Q96J02,P01889 2 +Establishment or maintenance of bipolar cell polarity 0.4497315879678195 0.5784582358125295 0.5629547863114823 1.0 1.0 15 P57105 1 +Response to ether 0.6726736493366852 0.5780673419458094 0.5632186547919962 1.0 1.0 3 P11802 1 +Behavior 0.4134512166239062 0.5760815623825942 0.5645600531763011 1.0 1.0 78 P54802,O15118,P30536,P17900,P05067,P50897,O75844,P10253,P04062,Q13641,Q92542 11 +Extracellular vesicle biogenesis 0.4613880743587873 0.5754662226893132 0.5649760282382654 1.0 1.0 10 O00560,Q99816,Q92905 3 +Negative regulation of viral transcription 0.5212567753241316 0.5744187255940414 0.5656844843212099 1.0 1.0 4 P19474,Q13049 2 +Regulation of stress granule assembly 0.6712834718374912 0.5735443741796274 0.5662761629241515 1.0 1.0 3 Q9UN86,Q13283 2 +Regulation of peptidyl serine phosphorylation 0.4365800924414831 0.5733864370092059 0.566383071566436 1.0 1.0 18 O95429,P35080,P07900,P05067,Q92600,P08238,P63244,P02786,P14174,Q13043 10 +Metanephric tubule development 0.520970800773243 0.5733571499705404 0.5664028972072856 1.0 1.0 4 P35610 1 +Metanephric epithelium development 0.520970800773243 0.5733571499705404 0.5664028972072856 1.0 1.0 4 P35610 1 +Microglial cell activation 0.5208294773220266 0.5728327591383772 0.566757935977507 1.0 1.0 4 P05067 1 +Mitochondrial membrane organization 0.3591649641214794 0.5703848650043303 0.5684166925683884 1.0 1.0 47 Q13505,O60313,Q9NS69,P45880,P52789,P0DP25,Q9Y584,O14737 8 +Vascular transport 0.4557489881787749 0.5667440275605049 0.5708881035396418 1.0 1.0 12 P33527,P08183,P41440 3 +Neutrophil activation involved in immune response 0.6688413329335732 0.5656282945424839 0.5716464892514042 1.0 1.0 3 Q15833 1 +Neutrophil degranulation 0.6688413329335732 0.5656282945424839 0.5716464892514042 1.0 1.0 3 Q15833 1 +Protein localization to lysosome 0.434734212090364 0.5638068294104406 0.5728856034713985 1.0 1.0 18 Q14108 1 +Dicarboxylic acid metabolic process 0.3542347466090618 0.5596755166864111 0.5757007851393159 1.0 1.0 45 O75874,P48735,Q9H2D1,P41440,Q9H9P8,P00367 6 +Cellular response to dsrna 0.4597006622691356 0.5593359332323948 0.5759324762458575 1.0 1.0 8 Q9NUD5,P41440 2 +Biological process involved in interaction with host 0.3700226104547224 0.5581439978514938 0.5767460585281698 1.0 1.0 54 P19474,P07237,P11279,O15118,Q9UQN3,Q14108,Q96FV9,Q8WTV0,Q9UPT5,Q9BTY2,O14786,Q9H9H4 12 +Multicellular organismal movement 0.4570738779558471 0.5566358073981571 0.577776283695262 1.0 1.0 10 P10253,Q99622 2 +Establishment of protein localization to mitochondrial membrane 0.4375363138417608 0.5557870674871406 0.5783564273984587 1.0 1.0 17 Q9NS69,Q9Y584 2 +Regulation of protein autophosphorylation 0.4575129045390631 0.5534425343973963 0.5799604201224697 1.0 1.0 9 P0DP25,Q15375 2 +Fluid transport 0.6649131059042144 0.5529753837234644 0.580280266372839 1.0 1.0 3 Q99797 1 +Phospholipid dephosphorylation 0.458334843323366 0.5520013961685979 0.5809473967104897 1.0 1.0 7 Q9C0I1,Q10713 2 +Regulation of tau protein kinase activity 0.5140000975511642 0.547669735118541 0.5839186968370156 1.0 1.0 4 P08238,P06400 2 +Regulation of protein targeting to membrane 0.4533030578763884 0.5469438518252947 0.5844173074805419 1.0 1.0 11 Q9NQG6,Q9Y3D6,P27105 3 +Glial cell development 0.4161263764635889 0.5468327025784679 0.584493673598633 1.0 1.0 21 Q9UI10,Q8IXJ6,Q92542,P05067 4 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.442737220770576 0.5446894922851111 0.5859670929179883 1.0 1.0 15 O43657 1 +Neutrophil mediated immunity 0.4856795030540172 0.5444223840657874 0.586150845823902 1.0 1.0 5 Q15833 1 +Inflammatory response to antigenic stimulus 0.4527203121389171 0.5377733242703342 0.5907335504852855 1.0 1.0 10 Q16539,P28070,Q04721 3 +Golgi to plasma membrane transport 0.395615690845454 0.5372348908219261 0.5911053732150946 1.0 1.0 24 Q8IYI6,Q4J6C6,P63244,P50570,Q8N2H4 5 +Regulation of ossification 0.4534716715920605 0.5362757222716816 0.5917680068868556 1.0 1.0 9 O75844 1 +Regulation of proteasomal protein catabolic process 0.39473631422106 0.5357555170928505 0.5921275289602268 1.0 1.0 70 P53350,Q6ZXV5,Q9NRR5,P54725,P49069,P61289,Q96HY6,Q8IXJ6,Q9UL15,Q9UL46,P08238,P63244,O00560,P46379,P04062,Q92530,O75832,O15372,P54727,Q9GZP4,Q4ZIN3 21 +Regulation of exosomal secretion 0.4527477310478544 0.5332136364197587 0.593885703017734 1.0 1.0 9 O00560 1 +Blastoderm segmentation 0.6584494403611846 0.5323777806878028 0.5944643710819932 1.0 1.0 3 O14786 1 +Digestive system process 0.4508831834063307 0.5298576603851167 0.5962106236119606 1.0 1.0 10 Q14651,Q8WTV0 2 +Inositol metabolic process 0.6575376365603554 0.5294949718150493 0.5964621315811873 1.0 1.0 3 P29218 1 +Terpenoid metabolic process 0.418215856219265 0.5283569890169025 0.5972515841550772 1.0 1.0 20 P51648,Q9HB40,Q6NUM9 3 +Exploration behavior 0.6569527962908435 0.5276489321073833 0.5977430239994839 1.0 1.0 3 Q05086 1 +Negative regulation of microtubule polymerization 0.4521850634157432 0.5273064914684505 0.5979807670810318 1.0 1.0 6 P04350,Q15691,P16949 3 +Endosomal vesicle fusion 0.6568174823022499 0.5272221533185302 0.5980393263347925 1.0 1.0 3 Q9UN37,Q8WUH2 2 +Mesenchyme morphogenesis 0.6561886690524856 0.525240554246575 0.599415976237553 1.0 1.0 3 Q9Y6N7 1 +Protein kinase c signaling 0.5073319050471303 0.5234510985807103 0.6006603728379301 1.0 1.0 4 P41440 1 +Positive regulation of rna export from nucleus 0.5072072440356379 0.5230017666977156 0.6009730238110136 1.0 1.0 4 P52298 1 +Positive regulation of nucleobase containing compound transport 0.5072072440356379 0.5230017666977156 0.6009730238110136 1.0 1.0 4 P52298 1 +Homologous chromosome segregation 0.4454751929958822 0.5205143129009538 0.6027051546499429 1.0 1.0 12 P46379 1 +Alpha ketoglutarate transport 0.7993846153846178 0.5199769540469802 0.6030796378743317 1.0 1.0 2 Q9BQT8 1 +Oxaloacetate transport 0.7993846153846 0.5199769540469301 0.6030796378743666 1.0 1.0 2 Q9UBX3 1 +Succinate transmembrane transport 0.7993846153846 0.5199769540469301 0.6030796378743666 1.0 1.0 2 Q9UBX3 1 +Nuclear envelope organization 0.3292028664805415 0.5188852037565503 0.6038407964746977 1.0 1.0 34 Q9UH99,O75844,Q86XL3,Q8IXJ6 4 +Response to transforming growth factor beta 0.3255274130671529 0.5187689750539048 0.6039218555081463 1.0 1.0 32 P46108,O00560,Q06481,P46109,Q92896,O14737 6 +Intracellular protein transmembrane transport 0.3924594762596709 0.5181866173677432 0.6043280710314907 1.0 1.0 24 Q99595 1 +Establishment of protein localization to membrane 0.425335743279422 0.5172044649112465 0.6050134355418186 1.0 1.0 90 P43307,Q9Y3D6,O15118,Q9NS69,Q15904,Q9H0F7,Q15629,P27105,O14737,P31150,P0DP25,O60725,Q9H9H4,Q9Y584,Q15907,Q9HD20,Q4J6C6,Q9P0J0,P63244,O00560,P46379,O43681,Q7L5D6,Q8N2H4,Q9Y5Y5,Q9NQG6,Q9H8Y8 27 +Regulation of dna methylation 0.4493790277822814 0.5164173649814264 0.6055629401080038 1.0 1.0 8 O75844,O95983 2 +Positive regulation of cell junction assembly 0.4461725167987486 0.5156505283798991 0.6060985129223615 1.0 1.0 11 O14786,P41440,Q13641 3 +Regulation of neutrophil migration 0.4491768982029378 0.5155851235827679 0.6061442026448787 1.0 1.0 8 Q00013,Q8NE86,P84095,O94813,O00429 5 +Regulation of receptor signaling pathway via stat 0.4482917784518671 0.5118069292025206 0.6087861403419303 1.0 1.0 6 Q9NX40,P30153 2 +Pyrimidine deoxyribonucleotide metabolic process 0.447186615397199 0.5074081156455209 0.6118684925069775 1.0 1.0 8 Q9H773,P13051 2 +Positive regulation of i kappab kinase nf kappab signaling 0.3386064760936513 0.5071070388710379 0.6120797164298639 1.0 1.0 40 Q8TB61,Q9UDY8,O43657,P09601 4 +Mitochondrial electron transport nadh to ubiquinone 0.390614139440944 0.5071039373301064 0.6120818925199369 1.0 1.0 24 O75380,O43676,O95182,O95168,O75306 5 +Peptidyl lysine hydroxylation 0.4470117067159408 0.5067368995581601 0.6123394361779617 1.0 1.0 6 O60568,Q96AY3,Q92791,Q9H267,O00469 5 +Digestion 0.4439841162977154 0.5061308709579246 0.6127647801450742 1.0 1.0 11 Q14651,Q8WTV0 2 +Positive regulation of cold induced thermogenesis 0.4421091205296616 0.5055570418231184 0.6131676450412384 1.0 1.0 12 P23786,P40939 2 +Negative regulation of collateral sprouting 0.7938461538461398 0.504475044076818 0.6139275948467353 1.0 1.0 2 Q15375 1 +Collateral sprouting in absence of injury 0.7938461538461343 0.5044750440768022 0.6139275948467464 1.0 1.0 2 P05067 1 +Oxidative phosphorylation 0.3735226140703426 0.5042413662552345 0.6140917748459136 1.0 1.0 60 P14406,Q9BSK2,O75380,P00403,O43676,P22695,Q9UDW1,P24539,O75964,Q96QE5,O95168,O95182,Q9Y6M9,O75306 14 +Inflammatory response 0.3819629052761973 0.5031446197648636 0.6148625977373352 1.0 1.0 65 Q9BQE5,Q8NCG7,P05067,Q8IV08,P42785,Q06481,P33527,P09601,P04062,P04083,Q16539,Q8N2K0,P60900 13 +Cell chemotaxis 0.3319149581628626 0.4970568727929504 0.6191489460833699 1.0 1.0 37 P46109,Q8NE86,Q92538,P46108,P84095,P33527,Q13641,P04083,O14786,O94813,P14174,Q00013 12 +Regulation of dendritic spine morphogenesis 0.4415339585620462 0.4955218590796774 0.6202317959387496 1.0 1.0 11 P61160,Q05086,Q9UQB8 3 +Skeletal system morphogenesis 0.4119667108647788 0.4948855521954302 0.6206809097123434 1.0 1.0 20 Q93063,Q9NVX2,O75844,Q16539,Q92896,O95470 6 +Positive regulation of nf kappab transcription factor activity 0.3321364055043569 0.4943719569819532 0.6210435151408968 1.0 1.0 31 P19474,P05067,P41440,P60900,Q9UDY8 5 +Pigmentation 0.4251113821959285 0.493801583631244 0.6214463146396616 1.0 1.0 17 Q15907,Q8TAA9,Q13561,Q86YV9,P63244,P21359,Q9H0F7,Q9BXS5 8 +Positive regulation of cyclin dependent protein kinase activity 0.4982489369412301 0.4910572498714846 0.6233859565610476 1.0 1.0 4 P08238,O75832 2 +Glial cell migration 0.4386191522005877 0.4901550124073189 0.6240242123863693 1.0 1.0 12 P30536,Q96G23,Q96N66 3 +Sequestering of metal ion 0.6448323020749602 0.4899390569070307 0.6241770243190381 1.0 1.0 3 P02792 1 +Positive regulation of lipid storage 0.470657131391868 0.4877591999100566 0.6257204139217984 1.0 1.0 5 Q8WTV0 1 +Mesoderm morphogenesis 0.4423074198952019 0.4875018085484908 0.6259027614980033 1.0 1.0 8 P10644,Q93063 2 +Positive regulation of protein polyubiquitination 0.4972290640393993 0.4874648703025973 0.6259289320846371 1.0 1.0 4 O00571,P61088,O75150 3 +Positive regulation of keratinocyte proliferation 0.7870769230769189 0.4857935479007018 0.6271135493450837 1.0 1.0 2 Q6ZWJ1 1 +Renal system vasculature morphogenesis 0.7870769230769175 0.4857935479006987 0.6271135493450859 1.0 1.0 2 O14786 1 +Negative regulation of intracellular protein transport 0.437328162223354 0.484485763222918 0.6280411657116345 1.0 1.0 12 Q13438,P31150,O95429,P21359,O95817,P49257 6 +Ephrin receptor signaling pathway 0.4415057518559728 0.4842506579662188 0.6282079890967429 1.0 1.0 8 P46108 1 +Neuroblast proliferation 0.4388710821525632 0.4840525635213742 0.628348565504182 1.0 1.0 11 Q8NCG7 1 +Cellular aldehyde metabolic process 0.3990529463831478 0.4835760329917613 0.6286867874397433 1.0 1.0 22 O75874,P48735 2 +Respiratory electron transport chain 0.3515248718213336 0.4826774651476154 0.629324766272525 1.0 1.0 49 O75380,P00403,O43676,Q9UDW1,O95168,O95182,P04062,O75306 8 +Positive regulation of epithelial cell proliferation 0.398748130984944 0.4818691942519987 0.6298988711616997 1.0 1.0 22 O14786,P09601,Q6ZWJ1 3 +Positive regulation of embryonic development 0.4406979426253349 0.480695471356283 0.6307329502262875 1.0 1.0 7 Q4VCS5 1 +Negative regulation of phosphoprotein phosphatase activity 0.4401975302827518 0.4787096519828628 0.6321451983640141 1.0 1.0 7 P04899,O14920,Q15257,P49841,O75116 5 +Positive regulation of mitochondrion organization 0.3858066421389363 0.4784298183301589 0.6323443147440879 1.0 1.0 24 Q9Y3D6,P21796,Q8NE86,P11233,Q9NQG6,Q96A26,O14737 7 +Response to ischemia 0.4386864498571273 0.4780176407629558 0.6326376493388155 1.0 1.0 10 O95831,P52789,Q9NQ88,Q15018 4 +Positive regulation of endocytosis 0.4084679736264321 0.4763313341810972 0.6338383454640069 1.0 1.0 20 Q99816,O75955,P50570,P50897,Q06481,P41440 6 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.4669997840462609 0.4742523919290231 0.6353199365406683 1.0 1.0 5 P07237,O15460 2 +Female sex differentiation 0.430554031383379 0.4739313577115484 0.6355488570460197 1.0 1.0 14 O75874,Q05086,Q9UI10,O95470 4 +Hormone transport 0.3216665843306664 0.473453784494894 0.6358894655704148 1.0 1.0 33 O43768,Q15907,Q6ZWJ1,Q8N183,Q8NE86,P30626,P40939,P04083,P00367 9 +Cytokine production involved in immune response 0.4361980774831692 0.4726052422569323 0.6364948417364182 1.0 1.0 11 P09601 1 +Neural nucleus development 0.416755819215879 0.472160656787296 0.636812119664524 1.0 1.0 18 P24539,P11413,O15027,P0DP25,P00367,Q8IXJ6 6 +Regulation of response to interferon gamma 0.6381956724224073 0.4697529789020952 0.6385315121926975 1.0 1.0 3 Q16543 1 +Actomyosin contractile ring organization 0.4647319745100779 0.4659377058105601 0.6412600907188846 1.0 1.0 5 Q9UN37,Q9H0H5 2 +Positive regulation of nucleocytoplasmic transport 0.3371638036674038 0.4634645525058865 0.6430314174932321 1.0 1.0 30 Q16539,Q9C0E2,P08238,O00459,Q05D32,Q9BVS4,O95817,P52298,Q07666 9 +Sulfur compound biosynthetic process 0.3418555552359908 0.4626399461240785 0.6436224707296083 1.0 1.0 45 Q9UMR5,Q9UKU0,Q93063,P50897,P35610,Q8NCH0,Q8N6G5,Q8TB61,Q9NZ01,Q15118,Q53GQ0,O43505,Q13126 13 +Protein retention in golgi apparatus 0.7784615384615394 0.4624546717173434 0.6437553009328845 1.0 1.0 2 Q709C8 1 +Nervous system process 0.4353207090356089 0.4619697764087148 0.6441029945143113 1.0 1.0 101 P17900,P05067,Q99797,Q00169,Q9UQN3,P50897,Q14108,O75844,Q9UQB8,O14773,P10253,P04062,Q13641,Q9H0F7,Q92542,Q9H6K4,Q9Y6M9 17 +Positive regulation of peptidase activity 0.3361954764772065 0.4601623618209584 0.6453996846907308 1.0 1.0 42 Q9Y3D6,Q9UL46,Q9P0J0,P05067,P63244,Q9BXK5,Q92542,Q9UDY8,Q96A26,O14737 10 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4244988559753529 0.4586758706840138 0.6464669440472963 1.0 1.0 15 P42575,Q9Y6N7,P63244,O95831,Q9BXK5,P63167,Q96A26,Q92688 8 +Motor neuron axon guidance 0.4344707845746929 0.4577923267678626 0.6471016490793902 1.0 1.0 6 O14786,P84095 2 +Regulation of er to golgi vesicle mediated transport 0.4344195587518608 0.4575952401468335 0.6472432638062531 1.0 1.0 6 Q9P2W9,Q9NR31 2 +Regulation of mitochondrial atp synthesis coupled electron transport 0.6337353370150376 0.4563791677820161 0.6481173434679497 1.0 1.0 3 P06493 1 +Cerebellar cortex development 0.4319596260043467 0.4545934813567512 0.6494017253017426 1.0 1.0 11 P04062 1 +Cell killing 0.4042964717228351 0.4543955276678846 0.6495441707528915 1.0 1.0 20 Q9NUQ9,P04439,Q9BY67,P46108,P01889,P53634,Q15833,P51809,P11279 9 +Membrane biogenesis 0.368040895723211 0.4542460660665806 0.649651730283324 1.0 1.0 26 Q9UQN3,Q96CP7,Q86XL3,P41440,Q8IXJ6 5 +Cerebral cortex tangential migration 0.7753846153846187 0.4542418382412288 0.649654772929602 1.0 1.0 2 Q9Y6N7 1 +Olfactory bulb interneuron differentiation 0.7753846153846187 0.4542418382412288 0.649654772929602 1.0 1.0 2 Q9Y6N7 1 +Olfactory bulb interneuron development 0.7753846153846187 0.4542418382412288 0.649654772929602 1.0 1.0 2 Q9Y6N7 1 +Regulation of chemokine mediated signaling pathway 0.7753846153846187 0.4542418382412288 0.649654772929602 1.0 1.0 2 Q9Y6N7 1 +Negative regulation of chemokine mediated signaling pathway 0.7753846153846187 0.4542418382412288 0.649654772929602 1.0 1.0 2 Q9Y6N7 1 +Luteolysis 0.7753846153846126 0.4542418382412121 0.649654772929614 1.0 1.0 2 P42575 1 +Neuron projection extension involved in neuron projection guidance 0.7753846153846076 0.4542418382411983 0.649654772929624 1.0 1.0 2 O14786 1 +Regulation of retinal ganglion cell axon guidance 0.7753846153846076 0.4542418382411983 0.649654772929624 1.0 1.0 2 O14786 1 +Positive regulation of actin filament polymerization 0.4318107289026567 0.4539639246659949 0.6498547922804749 1.0 1.0 11 Q9UQB8,O95429 2 +Arachidonic acid secretion 0.7750769230769052 0.4534241698694959 0.6502433355149737 1.0 1.0 2 P04083 1 +Positive regulation of protein localization to early endosome 0.4873768472906309 0.4532547867784255 0.65036528577608 1.0 1.0 4 P26038,P35241,O75116 3 +Regulation of protein localization to endosome 0.4873768472906309 0.4532547867784255 0.65036528577608 1.0 1.0 4 P26038,P35241,O75116 3 +Positive regulation of cardiac muscle cell proliferation 0.7741538461538345 0.4509751354851599 0.6520074696653066 1.0 1.0 2 Q16539 1 +Regulation of cardiac muscle cell proliferation 0.7741538461538345 0.4509751354851599 0.6520074696653066 1.0 1.0 2 Q16539 1 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3346518336237102 0.4482111151800043 0.6540008416239913 1.0 1.0 42 P53350,O75832,Q6ZXV5,Q4ZIN3,P54725,P63244,P53634,P46379,P04062,Q96HY6,Q8IXJ6 11 +Branching involved in blood vessel morphogenesis 0.4598067736549954 0.4480446346334982 0.6541209840371078 1.0 1.0 5 O14786 1 +Protein localization to microtubule end 0.7729230769230782 0.4477190574339796 0.6543559660981992 1.0 1.0 2 Q15555 1 +Fatty acyl coa biosynthetic process 0.4270014406027594 0.4476832311602369 0.6543818254425098 1.0 1.0 13 P50897,Q9UMR5,Q9UKU0 3 +Signal release 0.3555665481471892 0.4465476623323797 0.6552016918975574 1.0 1.0 54 O43768,Q15907,Q6ZWJ1,Q4J6C6,Q8N183,Q8NE86,P30626,P40939,Q7L0J3,P50897,Q15833,P0DP25,P04083,P00367 14 +Serine transport 0.6300400123114837 0.4454200839436781 0.6560162008266699 1.0 1.0 3 Q96NB2,Q15758 2 +Membrane protein proteolysis 0.4308327581522347 0.4453494005559101 0.65606727277756 1.0 1.0 10 Q9NZ08,Q92542 2 +Regulation of neurotransmitter transport 0.4180896302612607 0.4430039694853627 0.6577628635357344 1.0 1.0 16 P0DP25,P41440,Q4J6C6 3 +Unsaturated fatty acid biosynthetic process 0.4307584871288549 0.4412296067348268 0.6590467814317815 1.0 1.0 8 Q8NCG7,P04083 2 +Negative regulation of response to external stimulus 0.3495870501807004 0.440866512155254 0.659309638468478 1.0 1.0 51 P19474,Q96G23,P80303,P04439,P28070,P06400,O43657,P46108,P01889,P04062,Q16539,O14786,Q8IXJ6 13 +Peptidyl lysine monomethylation 0.7701538461538482 0.4404320482348584 0.6596242175987694 1.0 1.0 2 Q8WTS6 1 +Amyloid beta clearance 0.428209649152769 0.4388061404828503 0.6608020106136556 1.0 1.0 11 Q16850,P04035 2 +Response to insulin 0.3648103961943234 0.4380884885708635 0.6613221387802679 1.0 1.0 60 Q9BSK2,Q6ZWJ1,P43490,Q9Y5X3,Q16836,Q92572,Q15043,P06400,P40939,P42224,Q06481,Q9UQB8,Q709C8,Q16539,Q96A49 15 +Positive regulation of protein targeting to membrane 0.4288417938315945 0.4371638520593386 0.661992522983607 1.0 1.0 10 Q9Y3D6,P27105 2 +Lysine metabolic process 0.4824735974704395 0.4365762833136954 0.662418665638447 1.0 1.0 4 Q9BQT8 1 +Regulation of attachment of spindle microtubules to kinetochore 0.4293100977376846 0.4364876838341274 0.662482933169563 1.0 1.0 9 Q96R06,Q8IXJ6 2 +Response to acetylcholine 0.6266543551862143 0.4354777509719678 0.6632156851501327 1.0 1.0 3 P04899,P46109 2 +Maintenance of location 0.3830273962052329 0.4348798245549167 0.6636496597664276 1.0 1.0 71 Q9H6V9,P30536,P24390,P17900,Q9UH99,O43731,P10253,P0DP25,P04062,Q8WTV0,P02792 11 +Threonine metabolic process 0.6263408180931369 0.4345618440729826 0.6638804957765159 1.0 1.0 3 P52758 1 +Pattern recognition receptor signaling pathway 0.3331463593959388 0.43440275884234 0.6639959947118159 1.0 1.0 30 Q06481,Q9NUD5,O43657,P41440 4 +Negative regulation of hemopoiesis 0.4289681804720329 0.4341699291594702 0.6641650479260857 1.0 1.0 8 P09429,O15347,P21359,P04083 4 +Reactive oxygen species biosynthetic process 0.4280777763840284 0.4340334192658289 0.664264173117187 1.0 1.0 10 Q15067,Q9BSK2,Q92538,P00403 4 +Steroid biosynthetic process 0.3343858168167948 0.4324609285700666 0.6654064434472242 1.0 1.0 43 P04035,Q9UHI6,P16435,Q13510,P30536,P14324,Q15392,P37268,Q14739,Q16850,Q53GQ0,O14975 12 +Regulation of peptidyl lysine acetylation 0.4157266226775428 0.4319319310695084 0.6657908864220126 1.0 1.0 16 O75844 1 +Nik nf kappab signaling 0.4041953898557795 0.4303434684720443 0.6669458113359834 1.0 1.0 19 P05067,O43657 2 +Regulation by virus of viral protein levels in host cell 0.4804549646490199 0.429779814377824 0.667355817783031 1.0 1.0 4 P42224 1 +Dendritic spine morphogenesis 0.422518877852946 0.4280830591473874 0.6685906501183199 1.0 1.0 13 P61160,Q05086,Q9UQB8 3 +Positive regulation of t cell proliferation 0.4257252492355574 0.4244323054645056 0.6712505647310487 1.0 1.0 10 P30825,P49366,P04439,P04083,Q9HCL2 5 +Hormone biosynthetic process 0.425696280713595 0.422033887068799 0.6730002830984054 1.0 1.0 9 P30536,Q53GQ0 2 +Ovarian follicle development 0.4253016443239034 0.4206565850973932 0.674005867805723 1.0 1.0 7 Q05086,Q9UI10 2 +Long chain fatty acyl coa biosynthetic process 0.4253877136343601 0.4201478017632519 0.6743774841139993 1.0 1.0 8 Q9NZ01,Q9UKU0 2 +Negative regulation of reactive oxygen species metabolic process 0.4241424770461146 0.4180054907171855 0.6759431027593081 1.0 1.0 10 P52789,Q9NQ88,Q8IXJ6 3 +Autophagosome maturation 0.4016834573305661 0.4177314555080448 0.6761434712676797 1.0 1.0 19 Q99816,Q9NRR5,Q9UQN3,Q13137,P13473 5 +Regulation of dna templated transcription in response to stress 0.4228458286712715 0.4164789827035218 0.6770595436039006 1.0 1.0 11 P09601 1 +Pentose metabolic process 0.4505697566985117 0.4151245002948744 0.6780507647997474 1.0 1.0 5 Q9UKK9,Q7Z4W1,Q8NBZ7,P11413 4 +Nonribosomal peptide biosynthetic process 0.6195752539242875 0.4150015033199473 0.6781408026157674 1.0 1.0 3 Q8WUX2,P48637 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.4754714944673961 0.4131809941257609 0.6794740118459943 1.0 1.0 4 Q16543 1 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.7587692307692333 0.4110576764664275 0.6810302432271513 1.0 1.0 2 Q15043 1 +Central nervous system projection neuron axonogenesis 0.4744391132018286 0.4097749978298899 0.6819710084966553 1.0 1.0 4 Q99622 1 +Positive regulation of pattern recognition receptor signaling pathway 0.4220874198316142 0.4097011253897092 0.6820252044276669 1.0 1.0 10 Q9NUD5,P41440 2 +Oligodendrocyte development 0.4225507716786313 0.4095640781963817 0.6821257523603412 1.0 1.0 9 Q92542,Q9UI10 2 +Gamma aminobutyric acid secretion 0.7578461538461588 0.4087180284725911 0.6827466017692572 1.0 1.0 2 Q7L0J3 1 +Acid secretion 0.7578461538461588 0.4087180284725911 0.6827466017692572 1.0 1.0 2 Q7L0J3 1 +Gamma aminobutyric acid transport 0.7578461538461588 0.4087180284725911 0.6827466017692572 1.0 1.0 2 Q7L0J3 1 +Positive regulation of cyclase activity 0.7578461538461403 0.4087180284725448 0.6827466017692911 1.0 1.0 2 Q16539 1 +Regulation of anaphase promoting complex dependent catabolic process 0.6171129578331827 0.4079807409308467 0.6832878142656624 1.0 1.0 3 P53350,Q12834 2 +Regulation of action potential 0.4219591518614639 0.4072305271366379 0.683838682519162 1.0 1.0 9 P04062 1 +Negative regulation of muscle tissue development 0.6166916174262372 0.4067847089115226 0.6841661184293417 1.0 1.0 3 Q8IXJ6 1 +Negative regulation of muscle organ development 0.6166916174262372 0.4067847089115226 0.6841661184293417 1.0 1.0 3 Q8IXJ6 1 +Vesicle mediated transport to the plasma membrane 0.3345360063566024 0.406613082650767 0.6842921869861289 1.0 1.0 45 Q15907,Q8IYI6,Q4J6C6,Q9H4M9,P63244,Q15904,P50570,Q8N2H4,Q9H223 9 +Taxis 0.3674053218356328 0.4065719589068223 0.6843223958556666 1.0 1.0 64 P42892,P46108,Q15375,P33527,Q00013,Q8NE86,Q92538,Q4VCS5,Q04721,Q16539,Q9NUQ9,Q13509,P46109,P04083,O14786,O94813,P14174,Q9Y6N7,P05067,P11233,Q13641,P84095 22 +Regulation of transposition 0.6165393843641271 0.4063529604134758 0.6844832772850535 1.0 1.0 3 Q9HCE1 1 +Transposition 0.6165393843641271 0.4063529604134758 0.6844832772850535 1.0 1.0 3 Q9HCE1 1 +Cell differentiation involved in metanephros development 0.6163554317270493 0.4058315255294778 0.684866393197455 1.0 1.0 3 P42224 1 +Renal vesicle development 0.6163554317270493 0.4058315255294778 0.684866393197455 1.0 1.0 3 P42224 1 +Regulation of epithelial cell differentiation involved in kidney development 0.6163554317270493 0.4058315255294778 0.684866393197455 1.0 1.0 3 P42224 1 +Metanephric nephron development 0.6163554317270493 0.4058315255294778 0.684866393197455 1.0 1.0 3 P42224 1 +Nephron tubule epithelial cell differentiation 0.6163554317270493 0.4058315255294778 0.684866393197455 1.0 1.0 3 P42224 1 +Negative regulation of protein exit from endoplasmic reticulum 0.7566153846153885 0.4056085040852375 0.6850302793852032 1.0 1.0 2 Q13438 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.4207642521746014 0.4022379882615049 0.6875088872380655 1.0 1.0 8 Q92896 1 +Golgi to vacuole transport 0.4196677931602753 0.4018904980503993 0.687764615987561 1.0 1.0 6 P11279 1 +Regulation of endothelial cell development 0.4195933456561951 0.4016149437644402 0.6879674302657945 1.0 1.0 6 P18206,P35611,O14920,Q9Y624,O75116 5 +Cytosolic transport 0.3717648346164339 0.401326375286979 0.6881798473486485 1.0 1.0 67 O60499,O15498,Q4J6C6,Q8NBN3,O15260,O75503,Q8N2H4,Q13190 8 +Regulation of protein exit from endoplasmic reticulum 0.4199851417023797 0.400468463652339 0.6888115067679632 1.0 1.0 7 Q13438,Q9Y385,Q9NR31 3 +Response to xenobiotic stimulus 0.3699506220992874 0.4003847951976815 0.6888731214338621 1.0 1.0 66 O15217,P17812,P11802,O15118,P30536,O00170,P33527,P08183,P07099,P18887,Q16836,P33993,Q96K76,P50416,P16435,P08238,P06400,Q9NQ88,P09601,P46109,P06493,P40939,P42224,P04818,P27544,P12004,O43169 27 +Regulation of endothelial cell differentiation 0.4197226502311114 0.3994794459160423 0.6895399657329024 1.0 1.0 7 P18206,P35611,O14920,Q9Y624,P35222,O75116 6 +Wound healing spreading of epidermal cells 0.4456421311980429 0.397921493630567 0.6906880559159589 1.0 1.0 5 Q7Z460,P42345,O75122,Q96AC1 4 +Regulation of wound healing spreading of epidermal cells 0.4456421311980429 0.397921493630567 0.6906880559159589 1.0 1.0 5 Q7Z460,P42345,O75122,Q96AC1 4 +Innervation 0.6132735632709586 0.3971404040619699 0.6912639265409481 1.0 1.0 3 P42892 1 +Cellular carbohydrate catabolic process 0.4048349768636661 0.3961459109541618 0.6919973908099593 1.0 1.0 17 Q14108,P10253 2 +Negative regulation of cell activation 0.4103851713178302 0.3945092927467103 0.6932050677633006 1.0 1.0 15 Q96FV9,P09601,P04083 3 +Epoxide metabolic process 0.7516923076923101 0.3932858995762307 0.6941083314303833 1.0 1.0 2 P34913 1 +Regulation of skeletal muscle contraction 0.6115727916281966 0.3923805974075596 0.6947770199855885 1.0 1.0 3 Q99622,P28161 2 +Stem cell proliferation 0.4157577162905501 0.3922549810825723 0.694869823475373 1.0 1.0 12 P04062 1 +Nadph regeneration 0.4179635454254088 0.3915709643675331 0.6953752451581658 1.0 1.0 9 O95336,Q9NQ88,P11413 3 +Stress granule disassembly 0.6109572176054204 0.3906643010426683 0.6960453896186729 1.0 1.0 3 P33176,Q07866 2 +Cell communication by electrical coupling 0.4173311476824983 0.3905030527962861 0.69616459834061 1.0 1.0 7 P0DP25 1 +Detection of stimulus 0.4033440170493753 0.3891627571375625 0.6971557516721607 1.0 1.0 17 P04439,P30536,P01889,P0DP25,Q8WTV0,Q15555 6 +Endosomal transport 0.3850861339851982 0.3890273640180169 0.6972559041403814 1.0 1.0 76 O60499,O15498,Q4J6C6,Q8NBN3,O15260,Q9H4M9,Q15904,O75503,Q13190 9 +Steroid hormone biosynthetic process 0.4166862902831831 0.3880933084500595 0.6979469837179919 1.0 1.0 7 P30536 1 +Positive regulation of t cell cytokine production 0.6098690986817937 0.3876389368049173 0.6982832502314313 1.0 1.0 3 Q9UDY8 1 +T cell cytokine production 0.6098690986817937 0.3876389368049173 0.6982832502314313 1.0 1.0 3 Q9UDY8 1 +T cell tolerance induction 0.7486153846153645 0.3856793026983356 0.6997341931725944 1.0 1.0 2 P01889 1 +Lymphocyte anergy 0.7486153846153645 0.3856793026983356 0.6997341931725944 1.0 1.0 2 P01889 1 +Positive regulation of vascular endothelial cell proliferation 0.6088027085257036 0.3846845020937113 0.7004711787944515 1.0 1.0 3 P09429,P40763 2 +Vascular endothelial cell proliferation 0.6088027085257036 0.3846845020937113 0.7004711787944515 1.0 1.0 3 P09429,P40763 2 +Cellular lipid catabolic process 0.3677842290922959 0.384491204287777 0.7006144138138062 1.0 1.0 66 P06280,O75874,Q8NCC3,P06865,P04066,Q13510,P17900,Q8NCG7,P23786,P40939,Q8NHP8,P50897,P04062,Q8WTV0,O95470 15 +Regulation of autophagy 0.4182467695275899 0.3841617960987444 0.7008585321011482 1.0 1.0 97 P19474,P21796,O15118,P30536,Q709C8,Q9UPT5,P07602,Q9NZ45,Q9NRR5,P10619,Q05639,Q9BXS4,Q13137,Q8IXJ6,O15269,Q8IYI6,Q9Y5X3,Q9Y487,O75844,Q9NQ88,Q9UIL1,P09601,P04062,Q93050,P04632 25 +Very long chain fatty acid metabolic process 0.4148436697682033 0.3837605678704655 0.7011559166148051 1.0 1.0 11 Q9NZ01,Q9UKU0,O14975 3 +Platelet derived growth factor receptor signaling pathway 0.4155908729303251 0.3823566879430181 0.702196812115758 1.0 1.0 9 O95470 1 +Protein k63 linked ubiquitination 0.4097341294045469 0.3814363091498482 0.7028795229994436 1.0 1.0 14 Q96FW1 1 +Positive regulation of calcium ion transmembrane transport 0.4142625457940805 0.3814134089254609 0.7028965127948714 1.0 1.0 11 P30626,P0DP25 2 +Regulation of dna damage response signal transduction by p53 class mediator 0.4139759555763398 0.3802573537549651 0.7037543888055453 1.0 1.0 11 O75844,O75832,P14174 3 +Regulation of wound healing 0.4071033152069647 0.3799324789130424 0.7039955372213758 1.0 1.0 15 P46108 1 +Cytoplasmic sequestering of transcription factor 0.4136208304922091 0.3797028651753029 0.704165993086816 1.0 1.0 6 Q9UN86,O75832,P30626 3 +Regulation of phosphoprotein phosphatase activity 0.4092030970284158 0.3791438937059362 0.7045810127992445 1.0 1.0 14 Q15257,P0DP25 2 +Mitochondrial transport 0.3902293071667103 0.3787294118973646 0.7048888100328645 1.0 1.0 80 Q10713,Q9Y3D6,P30536,Q99797,P55786,Q9NS69,P45880,P23786,O75964,Q9UBX3,Q99595,Q8N4H5,P52789,O43772,Q9Y584 15 +Trna wobble uridine modification 0.4129719893434191 0.3773459383190966 0.70591653723004 1.0 1.0 6 O75648 1 +Trna wobble base modification 0.4129719893434191 0.3773459383190966 0.70591653723004 1.0 1.0 6 O75648 1 +Cell cell adhesion mediated by cadherin 0.4126171601633406 0.3760590075126091 0.7068730284928799 1.0 1.0 6 P41440 1 +Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process 0.7433846153846202 0.3729188303077451 0.7092088567727097 1.0 1.0 2 Q93063 1 +Cellular response to insulin stimulus 0.3384908676599011 0.3706048439180021 0.7109318736802896 1.0 1.0 50 Q9BSK2,Q6ZWJ1,P43490,Q9Y5X3,Q96A49,P06400,Q92572,P42224,Q06481,Q9UQB8,Q15043 11 +Regulation of response to wounding 0.399191429588966 0.369871349748566 0.711478349550011 1.0 1.0 17 P46108,P04083 2 +Regulation of defense response to virus 0.3990946315794345 0.369424493996373 0.7118113436218727 1.0 1.0 17 O43657 1 +Regulation of post translational protein modification 0.6030634610979002 0.3689650186078125 0.7121537990918998 1.0 1.0 3 Q32P28 1 +Platelet activation 0.4017852062802343 0.3679987180977429 0.7128741900362705 1.0 1.0 16 Q16539,P53582,Q9Y624,Q9BWH2 4 +Protein polyufmylation 0.6018539587565229 0.365691733482085 0.7145951152414971 1.0 1.0 3 Q96HY6 1 +Reticulophagy 0.6018539587565229 0.365691733482085 0.7145951152414971 1.0 1.0 3 Q96HY6 1 +Glomerulus development 0.6018073830015185 0.3655659630067036 0.7146889771873199 1.0 1.0 3 Q04721 1 +Alcohol catabolic process 0.4059301832644291 0.365095026166288 0.7150404735778559 1.0 1.0 14 Q10713,Q8WTV0 2 +Positive regulation of mitotic cell cycle phase transition 0.3143541494955467 0.361605916232991 0.7176465429405017 1.0 1.0 31 P31350,P11802,P05067,P06400,P30260,P14635,P04083,Q9UJX4,Q13042,Q9NYL9,P06493 11 +Mannosylation 0.4094446439569055 0.3613540370142005 0.7178348030260262 1.0 1.0 7 Q6ZXV5 1 +Negative regulation of myeloid leukocyte differentiation 0.6001846722068365 0.3611970104457762 0.7179521768198369 1.0 1.0 3 Q00534,P21359 2 +Regulation of membrane potential 0.3472722259454313 0.3589026616973937 0.7196679083668633 1.0 1.0 56 Q9BSK2,P30536,P05067,O75844,Q9UQB8,P04062 6 +Negative regulation of stress activated protein kinase signaling cascade 0.4087546239210817 0.3568224722627618 0.7212247118123489 1.0 1.0 8 P15311,P43034,P51452,P31689,Q96KB5,Q96J02,P78318 7 +Response to monosaccharide 0.3302040157630956 0.3562994412616767 0.7216163277142209 1.0 1.0 29 Q6ZWJ1,Q15907,Q9UI10,Q8N183,P49770,P30626,Q15043,Q9HCL2 8 +Regulation of reactive oxygen species biosynthetic process 0.4083215907389249 0.35521632954816 0.722427532199277 1.0 1.0 8 Q9BSK2 1 +Regulation of homotypic cell cell adhesion 0.5976649384045747 0.354463045768607 0.7229918937236468 1.0 1.0 3 Q9Y624 1 +Hematopoietic stem cell homeostasis 0.4571255251761795 0.3544156234305504 0.7230274276677309 1.0 1.0 4 Q9NVX2,Q9NX40 2 +Endosome organization 0.3217007389256998 0.3534297740253736 0.7237662678116088 1.0 1.0 30 P51790,Q99816,Q8IYI6,Q9UQN3,Q14108,Q9UN37,Q9P253,Q86VS8,Q9H9H4 9 +Synapse assembly 0.3954699042278841 0.3527870512030935 0.7242480920604086 1.0 1.0 17 P05067,O00560,Q13641 3 +Regulation of neutrophil chemotaxis 0.4064257032790822 0.3503869741879157 0.726048300665235 1.0 1.0 7 Q8NE86,O00429,O94813,Q00013 4 +Response to nerve growth factor 0.4060894948702588 0.3488399232295242 0.7272094894435437 1.0 1.0 11 P05067,Q9H4M9,P46108 3 +Glycolytic process through fructose 6 phosphate 0.405986466850387 0.3465945746132923 0.7288959223885145 1.0 1.0 8 Q9BRR6 1 +Regulation of nik nf kappab signaling 0.4010861120730861 0.3445622180263045 0.730423513842346 1.0 1.0 14 O43657 1 +L aspartate transmembrane transport 0.4538094168022102 0.3442100386839834 0.7306883332945047 1.0 1.0 4 O75746 1 +Autophagy of nucleus 0.5937558491573184 0.3441381726158523 0.7307423765612397 1.0 1.0 3 Q7Z3C6 1 +Purine containing compound transmembrane transport 0.4047729779038105 0.3436718211430358 0.731093105229375 1.0 1.0 11 Q86VD7,Q8TB61 2 +Transferrin transport 0.4293186332180226 0.3428654962151856 0.7316996501160493 1.0 1.0 5 Q15907 1 +Regulation of synaptic vesicle exocytosis 0.4042383874629855 0.3415796796456714 0.7326672316506626 1.0 1.0 11 P0DP25 1 +Protection from non homologous end joining at telomere 0.4525270320802629 0.3402992352441744 0.7336311930151624 1.0 1.0 4 P18887,Q15554 2 +Negative regulation of plasma membrane bounded cell projection assembly 0.402452882953387 0.3398116353885642 0.7339983850219618 1.0 1.0 6 P50570,O94813 2 +Fatty acyl coa metabolic process 0.3954464546830747 0.3397866190225874 0.7340172254911688 1.0 1.0 16 P50897,Q9UMR5,Q9UKU0 3 +Regulation of cilium assembly 0.3954186951730088 0.3396643346719206 0.7341093232881326 1.0 1.0 16 P50570,Q8TC07,Q66K14,Q9Y277 4 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5918744228993573 0.3392224556841203 0.7344421539348591 1.0 1.0 3 P61254,P63241 2 +Regulation of myoblast differentiation 0.428049906084695 0.3387176826040425 0.7348224185119614 1.0 1.0 5 Q16539 1 +Ubiquitin recycling 0.4277794887588534 0.3378361687336618 0.7354866519932737 1.0 1.0 5 P14735,Q16763,Q13049,P61086 4 +Negative regulation of amyloid fibril formation 0.4028211057868942 0.3374367796345713 0.7357876626217001 1.0 1.0 7 Q9UHV9,Q9NQP4,P61758 3 +Histone h4 acetylation 0.3851943012254125 0.3371223543091162 0.7360246664986807 1.0 1.0 19 Q86UY6 1 +Fat cell differentiation 0.3272727364609542 0.3368022508425626 0.736265976187257 1.0 1.0 29 Q16539,Q9NZ08,Q8N4Q0,Q8IXJ6 4 +Granulocyte differentiation 0.4010985295888462 0.3350748989515738 0.7375685871862283 1.0 1.0 6 Q14739 1 +Eye morphogenesis 0.3995819588208713 0.3315033651108403 0.7402642995649797 1.0 1.0 13 P54802,Q14517,Q99622,Q04721,Q15555 5 +Regulation of response to endoplasmic reticulum stress 0.3755071792730843 0.3306441922479736 0.7409132613522511 1.0 1.0 21 O95881,O60313,P63244,Q92905,P46379,Q4ZIN3 6 +Endoplasmic reticulum to golgi vesicle mediated transport 0.3620078786784949 0.3306228420518075 0.7409293902138618 1.0 1.0 67 Q9P2W9,Q9Y282,O15498,Q96RQ1,P24390,Q92538,Q15437,O43731,O95070,Q9Y3B3,Q969X5,Q13190 12 +Multicellular organismal signaling 0.3706870448453469 0.3303079532713803 0.7411672840369423 1.0 1.0 22 O75844,P0DP25,P04062 3 +Visual behavior 0.4017853411922209 0.330075407081672 0.7413429851347253 1.0 1.0 9 P05067 1 +Regulation of transforming growth factor beta activation 0.7249230769230773 0.3296588174413699 0.7416577746299478 1.0 1.0 2 P08238 1 +Transforming growth factor beta activation 0.7249230769230773 0.3296588174413699 0.7416577746299478 1.0 1.0 2 P08238 1 +Adaptive immune response 0.3206807716352104 0.3294847361288906 0.7417893292821476 1.0 1.0 43 Q96FW1,Q6P179,Q03518,P10321,P01889,Q9UQ84,Q9NZ08,Q96FV9,P04083,Q9UDY8,P13051 11 +Regulation of lipid transport 0.3871211695375789 0.3293484031297097 0.7418923624984761 1.0 1.0 18 P30536,O15260 2 +Negative regulation of lipid storage 0.5875654047399235 0.3280971545928388 0.7428382053324429 1.0 1.0 3 Q96AD5,P06756 2 +Positive regulation of cell division 0.3970023917597385 0.327503625615631 0.7432870011897255 1.0 1.0 14 P67809,Q8IXJ6 2 +Rrna pseudouridine synthesis 0.4243198223209671 0.3266383329833222 0.7439414469171464 1.0 1.0 5 Q8IZ73 1 +Regulation of mammary gland epithelial cell proliferation 0.42429190014177 0.3265485671784432 0.7440093499783149 1.0 1.0 5 Q86VI3 1 +Positive regulation of epithelial cell migration 0.3256361927000714 0.3260055282549963 0.7444201724915835 1.0 1.0 29 Q16539,P04083,P09601,Q8WTV0 4 +Negative regulation of lipoprotein metabolic process 0.7230769230769206 0.3254897054972686 0.744810472656293 1.0 1.0 2 P06756 1 +Regulation of insulin secretion 0.3696865431418169 0.3251366176096506 0.7450776763634179 1.0 1.0 22 O43768,Q6ZWJ1,Q8N183,Q8NE86,P30626,P40939,P00367 7 +Nuclear membrane organization 0.3530503978114095 0.3246302077482961 0.7454609619491495 1.0 1.0 25 Q9UQN3,Q86XL3,Q8IXJ6 3 +Pyrimidine containing compound catabolic process 0.3994254131769109 0.321378784516969 0.7479233585861895 1.0 1.0 9 Q9H773 1 +Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.422275609269462 0.3200925870596349 0.7488981449493333 1.0 1.0 5 Q9NVX2 1 +Positive regulation of neuron projection development 0.3635958356722362 0.319971148023373 0.7489902022140862 1.0 1.0 23 Q14108,Q9UQB8,Q9H4M9 3 +Cellular response to peptide 0.3638030048448944 0.3196458195845442 0.7492368361418127 1.0 1.0 69 Q9BSK2,Q6ZWJ1,P43490,P16435,Q9Y5X3,P05067,Q15043,Q92572,P46108,P06400,P42224,Q06481,Q9UQB8,P33527,Q96A49 15 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3985669083449571 0.3196183952021146 0.7492576279441927 1.0 1.0 11 P46379,P14174,P61978 3 +Regulation of neural precursor cell proliferation 0.3949600961488941 0.3190618511524663 0.7496796113122264 1.0 1.0 14 P55209,Q06481,Q8IXJ6,Q9UKA9 4 +Response to mechanical stimulus 0.3811880794899014 0.3181636301128051 0.750360819359797 1.0 1.0 19 P49327,Q16539,P51797,P42224,Q9Y624,O95817,Q8N2K0 7 +Negative regulation of histone modification 0.3904583769988857 0.3179977245131071 0.750486662968816 1.0 1.0 16 Q01105,Q96FW1 2 +Regulation of protein tyrosine kinase activity 0.3981181799300269 0.3178994558534148 0.7505612053730077 1.0 1.0 11 P05067,Q99816,P63244 3 +Regulation of postsynapse organization 0.3896635240772084 0.3145605507677401 0.7530953355592929 1.0 1.0 16 Q9UQB8,Q15375 2 +Negative regulation of striated muscle cell differentiation 0.4201856886185974 0.3134556936592627 0.7539344770573537 1.0 1.0 5 P67809 1 +Regulation of ubiquitin dependent protein catabolic process 0.3475628369856067 0.3117356758638535 0.7552414126334657 1.0 1.0 60 P53350,O75832,Q9NRR5,P54725,P49069,P63244,P54727,O15372,Q05086,O00560,P46379,P04062,Q96HY6,Q8IXJ6,Q9UL15 15 +Cartilage development 0.3860059375593142 0.3102689838157558 0.7563564154148641 1.0 1.0 17 P16435,P06400,O75844,P04818,Q16539,Q15043,Q92896 7 +Regulation of protein acetylation 0.3756463441878725 0.3102004630267054 0.756408518441734 1.0 1.0 20 O75844 1 +Endoplasmic reticulum calcium ion homeostasis 0.3964232671632846 0.3101991919324885 0.7564094849888798 1.0 1.0 10 P05067 1 +Regulation of lipid storage 0.3961576663305655 0.3092137598348364 0.757158927628415 1.0 1.0 10 Q8WTV0 1 +Regulation of embryonic development 0.3792058863952889 0.3088816955275623 0.7574115212708206 1.0 1.0 19 Q4VCS5,P46379,Q9H0H5 3 +Positive regulation of calcium ion transport 0.3880990219666213 0.3078239037101283 0.7582163316563888 1.0 1.0 16 P30536,P0DP25 2 +Ribonucleoprotein complex localization 0.3937456614712725 0.3055579990906032 0.7599412036712208 1.0 1.0 7 Q8WWY3,Q9BVS4 2 +Response to ketone 0.3067412249910424 0.3048800230518938 0.7604575311710831 1.0 1.0 37 P49321,P16278,P30536,P04062,Q13126 5 +Delamination 0.7126153846153831 0.3024213195442302 0.7623309045192039 1.0 1.0 2 Q86U44 1 +Rna decapping 0.392650685539228 0.3017846222117503 0.7628162543477552 1.0 1.0 7 Q96C86,Q96DE0 2 +Organic hydroxy compound biosynthetic process 0.3289559499976623 0.301087558340665 0.7633477281011298 1.0 1.0 50 O15269,P35270,P04035,P00374,Q13510,P14324,Q15392,P37268,Q14739,P29218,P04062,Q16850,O14975 13 +Aggrephagy 0.5767744882109762 0.3010686358309967 0.763362157054494 1.0 1.0 3 O95817 1 +Bone morphogenesis 0.3937854096555609 0.3004558357311472 0.7638294790197679 1.0 1.0 10 O75844,Q93063,Q92896 3 +Plus end directed organelle transport along microtubule 0.7113846153846185 0.2997704129925305 0.7643522850260762 1.0 1.0 2 Q9Y496 1 +Anterograde dendritic transport 0.7113846153846163 0.2997704129925255 0.76435228502608 1.0 1.0 2 Q14254 1 +Cytoplasm organization 0.7113846153846051 0.2997704129925019 0.764352285026098 1.0 1.0 2 Q9Y2W6 1 +Aspartate family amino acid biosynthetic process 0.3916566575315063 0.2997592428683317 0.7643608059255158 1.0 1.0 13 O60568,Q99707,Q9NWL6,P08243,Q13126 5 +Regulation of mitochondrion organization 0.3217086547795185 0.2988482196951488 0.7650558571784756 1.0 1.0 46 O75832,Q9Y3D6,P21796,P30536,O60313,Q8NE86,Q99536,P11233,Q9NQ88,Q709C8,Q9NQG6,Q96A26,O14737 13 +Negative regulation of transmembrane transport 0.3686861423243019 0.2967821099535691 0.7666328646349738 1.0 1.0 21 Q06481,P0DP25,P21796 3 +Regulation of hormone secretion 0.3283378225295617 0.2958301211684063 0.7673598186411357 1.0 1.0 28 O43768,Q6ZWJ1,Q8N183,Q8NE86,P30626,P40939,P04083,P00367 8 +Apoptotic mitochondrial changes 0.3132605393921582 0.2957168202588326 0.7674463506915119 1.0 1.0 30 Q9Y3D6,O60313,P45880,P52789,Q96A26 5 +Regulation of protein targeting 0.3536052701072699 0.2954867856230428 0.7676220454777225 1.0 1.0 24 O95429,Q9Y3D6,P55786,Q9NQG6,P27105,O14737 6 +Negative regulation of response to endoplasmic reticulum stress 0.3901461372644645 0.2938137258422103 0.7689002460785999 1.0 1.0 13 O60313,O95881 2 +Cellular response to peptide hormone stimulus 0.3449665228867036 0.2933454846693866 0.7692580902572295 1.0 1.0 60 Q9BSK2,Q6ZWJ1,P43490,P16435,Q9Y5X3,Q15043,Q92572,P46108,P06400,P42224,Q06481,Q9UQB8,Q96A49 13 +Outflow tract morphogenesis 0.3909919525245686 0.2928938598502826 0.7696032822825691 1.0 1.0 8 O14786,P46109 2 +Negative regulation of jnk cascade 0.4359605911329947 0.2916480778772908 0.7705557118231128 1.0 1.0 4 P43034,Q96J02,P31689 3 +Regulation of transcription regulatory region dna binding 0.3911249137887858 0.291477201045853 0.770686378192087 1.0 1.0 11 O75844,P30626 2 +Tissue migration 0.3289725668921066 0.2889033478838909 0.7726553416834792 1.0 1.0 51 P07737,Q9Y6N7,P42224,Q4VCS5,P42785,P57105,P09601,Q8WTV0,Q16539,O14786,P04083 11 +Response to activity 0.390356258216665 0.288616051012375 0.7728752110626225 1.0 1.0 11 P31930,Q9Y376,Q16836,P40939,P06493 5 +Negative regulation of peptidyl serine phosphorylation 0.7055384615384535 0.287362678629016 0.7738346347268041 1.0 1.0 2 P63244 1 +Positive regulation of protein containing complex disassembly 0.3880234498226996 0.2860186316537041 0.7748638514044393 1.0 1.0 7 Q13137,P04062 2 +Neutrophil differentiation 0.4335680407667116 0.2849191873835685 0.7757060555803914 1.0 1.0 4 Q14739 1 +Aspartate family amino acid metabolic process 0.356697200804385 0.2838397383038269 0.7765331996124027 1.0 1.0 23 O60568,P52758,O75600,Q9UDR5,Q9BQT8,O75746,Q99707,Q9NWL6,P08243,Q13126 10 +Negative regulation of mrna catabolic process 0.3513517692999558 0.2833996507458776 0.7768704960824959 1.0 1.0 24 P98175,P67809,Q14011,Q92804,Q16539,P35637 6 +Purine nucleotide transport 0.3843727881330046 0.2830838060038827 0.7771125950199913 1.0 1.0 15 Q86VD7,Q8TB61,P41440 3 +Mammary gland development 0.3562544618020402 0.2815536617684104 0.7782857757423782 1.0 1.0 23 Q13505,P52789,Q86VI3,P00403 4 +Phosphatidylinositol 3 kinase signaling 0.3872593321515911 0.2790584860327562 0.78019994136723 1.0 1.0 12 Q10713,Q8IXJ6 2 +Liver regeneration 0.3875933947100353 0.2779746101847573 0.7810318490799786 1.0 1.0 10 P04818,P09601,P12004,P62841 4 +Positive regulation of protein binding 0.3501438347831408 0.276965421707836 0.7818066573474858 1.0 1.0 24 P19474,O14786,P05067,P41440 4 +Positive regulation of inclusion body assembly 0.430688685690029 0.2769243431716078 0.7818382001415489 1.0 1.0 4 P62333,P49427 2 +Positive regulation of reactive oxygen species biosynthetic process 0.4304361028603146 0.2762284408925609 0.7823726140377285 1.0 1.0 4 P00403 1 +Dna replication initiation 0.3551818147827162 0.2760319941253916 0.7825234927353517 1.0 1.0 23 Q9Y619,Q14181,P49427 3 +Negative regulation of rna catabolic process 0.2938548247187757 0.2757141436170008 0.7827676315170984 1.0 1.0 32 Q96HR8,P98175,P67809,Q14011,Q92804,Q16539,P35637 7 +Fatty acid transport 0.377930844609177 0.2751241038996621 0.7832208936596499 1.0 1.0 17 O43772,Q9Y3D6,P23786,P04083 4 +Regulation of calcium ion transport 0.3247973916845588 0.2739913670353357 0.7840912560017208 1.0 1.0 28 P30536,P21796 2 +Positive regulation of nuclear division 0.3850375533480637 0.2739651713858393 0.7841113871835657 1.0 1.0 13 P06400,Q13042,Q8IXJ6,P30260 4 +Postsynapse to nucleus signaling pathway 0.6978461538461558 0.2715057216241744 0.7860020997040293 1.0 1.0 2 P52292 1 +Pteridine containing compound biosynthetic process 0.3836149805673366 0.2712752846593788 0.7861793139794768 1.0 1.0 7 P35270 1 +Regulation of rho protein signal transduction 0.380914739150498 0.269043525821573 0.7878961883203466 1.0 1.0 15 P52565,Q9Y6N7,O75955,Q9Y624,P41440,O14786 6 +Neuron death 0.3627065345960495 0.2658889133458623 0.7903247637266555 1.0 1.0 73 Q01105,P05067,P06400,P63244,P49427,Q15375,P50897,Q15392,Q9NQ88,P09601,Q92542,P04062,O14786,Q96A26 14 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.3836371914156499 0.2655044372976687 0.7906208920169584 1.0 1.0 12 Q9UQN3,Q9H9H4 2 +C4 dicarboxylate transport 0.3831296328307906 0.2634215123784965 0.7922257114761331 1.0 1.0 9 Q9UBX3,Q02978,O75746 3 +Positive regulation of establishment of protein localization to mitochondrion 0.3820879788645814 0.2584629419996287 0.7960496454882535 1.0 1.0 10 P55786 1 +Positive regulation of cellular protein catabolic process 0.3194318401380744 0.2580967116065276 0.7963322693865207 1.0 1.0 48 P53350,O75832,Q6ZXV5,Q4ZIN3,P07900,P54725,P63244,P53634,P46379,P04062,Q96HY6,Q8IXJ6 12 +Cell volume homeostasis 0.3814903056935785 0.2578044583211315 0.7965578235299253 1.0 1.0 9 Q9NUT2,P51797 2 +Negative regulation of protein dephosphorylation 0.381423288689695 0.2560184484516638 0.7979365921330404 1.0 1.0 11 P04899,O43768,O14920,Q15257,Q12972,P49841 6 +Monosaccharide catabolic process 0.3809953026029453 0.2557488928599874 0.7981447392378189 1.0 1.0 12 P52789,P16278 2 +Protein transmembrane import into intracellular organelle 0.3775254491957169 0.2554766799058979 0.7983549528838503 1.0 1.0 15 Q99595,O43615,O14925 3 +Developmental maturation 0.315425898274237 0.254263080998138 0.7992923197984685 1.0 1.0 46 P51790,Q9Y2W6,P07737,P05067,P06400,P11413,O75503,Q12768,O95696,P04818,P21359,P30153,P04062,Q9BXS5,Q15645,Q8IXJ6 16 +Amyloid fibril formation 0.3807329313051601 0.2537316221234485 0.7997029023989692 1.0 1.0 10 Q9UHV9,Q9NQP4,P05067 3 +Cardiolipin biosynthetic process 0.688615384615384 0.2531929267459609 0.8001191321202832 1.0 1.0 2 Q8WUK0 1 +Positive regulation by host of viral genome replication 0.3762684256169515 0.2524957439626673 0.8006579033890924 1.0 1.0 6 P27105 1 +Lipophagy 0.3994456421312059 0.2507762440718372 0.8019871092709763 1.0 1.0 5 O15269,P51149,Q9Y679,O15270 4 +Nuclear pore organization 0.3787728992847098 0.2501909736425078 0.8024396653231158 1.0 1.0 13 Q8NFH5,Q9BTX1 2 +Peptidyl lysine acetylation 0.3078121731742735 0.2496213102858718 0.8028802169674414 1.0 1.0 42 Q01105,O75844,Q86UY6,P46379 4 +Regulation of alternative mrna splicing via spliceosome 0.2983700370053256 0.2489922441348007 0.8033667808079652 1.0 1.0 31 Q8IY67,Q9UHX1,O95319,P98175,P52756,P51114,Q07666,P62995 8 +Glial cell differentiation 0.3041692583425048 0.248571104495774 0.8036925623181519 1.0 1.0 40 Q9UI10,P05067,P04062,Q92542,Q8IXJ6 5 +Regulation of signaling receptor activity 0.3771372523435303 0.2481135807517588 0.8040465281762588 1.0 1.0 14 O14786,P05067 2 +Endochondral bone morphogenesis 0.3763435368737216 0.2475711020010933 0.8044662720236784 1.0 1.0 7 O75844,Q93063 2 +Regulation of lipoprotein particle clearance 0.3743853329996582 0.246585263771977 0.8052292102515073 1.0 1.0 6 Q92945 1 +Fatty acid derivative biosynthetic process 0.3731191792045806 0.2453588941816049 0.8061785540315531 1.0 1.0 16 P50897,Q9UMR5,Q9UKU0 3 +Regulation of myelination 0.3783522757437513 0.2450990564143718 0.8063797335193346 1.0 1.0 11 Q8IXJ6,P53634 2 +Smooth muscle tissue development 0.6840000000000013 0.2443334075395347 0.8069726118986165 1.0 1.0 2 P21359 1 +Regulation of kidney development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Kidney mesenchyme development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Metanephric mesenchyme development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Cell proliferation involved in kidney development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Mesenchymal cell differentiation involved in kidney development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Metanephric mesenchymal cell differentiation 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Cell proliferation involved in metanephros development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Negative regulation of kidney development 0.6839999999999921 0.2443334075395178 0.8069726118986296 1.0 1.0 2 P42224 1 +Positive regulation of gastrulation 0.6839999999999885 0.2443334075395112 0.8069726118986347 1.0 1.0 2 P63244 1 +Regulation of steroid hormone biosynthetic process 0.6836923076923067 0.2437498680186971 0.8074245488371661 1.0 1.0 2 P16435 1 +Regulation of hormone biosynthetic process 0.6836923076923067 0.2437498680186971 0.8074245488371661 1.0 1.0 2 P16435 1 +Pentose phosphate shunt 0.3763507016389256 0.2434748346918383 0.8076375776513514 1.0 1.0 8 Q9NQ88,P11413 2 +Endocrine system development 0.3777239371967797 0.2428835908258918 0.8080955776283643 1.0 1.0 11 P30536,P04083 2 +Endodermal cell fate commitment 0.3966738527871898 0.2428593749584392 0.8081143375631417 1.0 1.0 5 Q6PD62,P35222,Q8N7H5,Q92541 4 +Cell fate commitment involved in formation of primary germ layer 0.3966738527871898 0.2428593749584392 0.8081143375631417 1.0 1.0 5 Q6PD62,P35222,Q8N7H5,Q92541 4 +Protein peptidyl prolyl isomerization 0.343525670508396 0.2422903935742893 0.8085551568734213 1.0 1.0 24 Q8WUA2,P30414,Q15257,Q96AY3,O00170,O43447,Q9Y237,Q9NWM8,Q9Y680,Q9Y3C6 10 +Regulation of granulocyte chemotaxis 0.3756720225623444 0.2412617524390495 0.8093522525321843 1.0 1.0 8 Q8NE86,O00429,O94813,Q00013 4 +Fertilization 0.3049456179012844 0.2407981927196568 0.8097115304151103 1.0 1.0 30 Q9Y2W6,P45880,Q05086,Q9GZP4,Q9NVM9,P16989,P46109,P06493 8 +Regulation of cell junction assembly 0.2924471169268154 0.2403100302895235 0.8100899197669507 1.0 1.0 34 P05067,Q15375,P41440,Q13641,O14786 5 +Peptidyl lysine dimethylation 0.3953026218957698 0.2389846665141853 0.8111174726376691 1.0 1.0 5 Q8WTS6 1 +Regulation of atpase coupled calcium transmembrane transporter activity 0.6809230769230763 0.238538082836191 0.8114637818087052 1.0 1.0 2 P54652 1 +Positive regulation of chromosome separation 0.3751603596279991 0.234578328027793 0.814536031969731 1.0 1.0 10 P06400,Q13042,P30260 3 +Protein k11 linked ubiquitination 0.3744919604236783 0.2342904761668512 0.8147594791096655 1.0 1.0 9 Q9H1A4,P30260,Q9UJX4,Q16763,Q9UJX3,Q13042,P68036 7 +Regulation of mononuclear cell migration 0.3697712181305744 0.2319335906246291 0.8165895942450923 1.0 1.0 16 P05067 1 +Regulation of carbohydrate metabolic process 0.2876090127245537 0.2311522705560055 0.8171965084533672 1.0 1.0 32 P05067,Q9BYT8,Q14108,O75844,Q5MIZ7,Q15118 6 +Embryonic brain development 0.3924255602208871 0.2309459364622452 0.8173568030692024 1.0 1.0 5 P62995 1 +Regulation of glucocorticoid metabolic process 0.6766153846153851 0.2305747343120771 0.8176451978387378 1.0 1.0 2 P05023 1 +Regulation of low density lipoprotein particle clearance 0.3919601058567092 0.2296570923189308 0.818358239091123 1.0 1.0 5 Q92945 1 +Response to interleukin 1 0.3708136005532161 0.2291996565558211 0.8187137395058879 1.0 1.0 15 P05067,P78318,P04083 3 +Fermentation 0.5437271540752664 0.2261202467506428 0.8211078977442656 1.0 1.0 3 Q9NQ88 1 +Glycolytic fermentation 0.5437271540752664 0.2261202467506428 0.8211078977442656 1.0 1.0 3 Q9NQ88 1 +Regulation of phosphatase activity 0.3659864817668825 0.225242956328035 0.8217902736015756 1.0 1.0 17 Q15257,O95429,P0DP25 3 +Mitochondrial depolarization 0.3902567560268319 0.2249684357645601 0.8220038294807972 1.0 1.0 5 P30536 1 +Threonine catabolic process 0.6732307692307704 0.2244412599085255 0.8224139687108649 1.0 1.0 2 P52758 1 +Myeloid dendritic cell activation 0.6726153846153892 0.2233377927177318 0.8232726156575474 1.0 1.0 2 Q04721 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.6726153846153881 0.2233377927177304 0.8232726156575485 1.0 1.0 2 P14174 1 +Chemokine c x c motif ligand 2 production 0.6726153846153881 0.2233377927177304 0.8232726156575485 1.0 1.0 2 P14174 1 +Negative regulation of interferon gamma production 0.6726153846153858 0.2233377927177261 0.8232726156575518 1.0 1.0 2 Q07021 1 +Positive regulation of dna ligation 0.672615384615386 0.2233377927177258 0.823272615657552 1.0 1.0 2 P18887 1 +Negative regulation of developmental growth 0.3719286423351254 0.2231386141479482 0.8234276261419602 1.0 1.0 12 Q7Z5J4,Q15375,P11413,O14786,Q8N0X7 5 +Protein acetylation 0.3194639313446935 0.2227356680867042 0.8237412394946824 1.0 1.0 51 Q01105,Q86UY6,O75486,Q14CX7,O75844,P46379 6 +Response to carbohydrate 0.2899111896673982 0.2225473769200824 0.8238877963648714 1.0 1.0 34 Q6ZWJ1,Q15907,Q9UI10,Q8N183,P49770,P30626,Q15043,Q9HCL2 8 +Negative regulation of intrinsic apoptotic signaling pathway 0.2933144154652068 0.2217432867200055 0.8245137309065078 1.0 1.0 36 P45880 1 +Regulation of acyl coa biosynthetic process 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 1.0 2 Q15118 1 +Hypoxia inducible factor 1alpha signaling pathway 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 1.0 2 Q15118 1 +Regulation of cell communication by electrical coupling involved in cardiac conduction 0.5399794825563213 0.2184002608517621 0.8271172623133947 1.0 1.0 3 P0DP25 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.3588221765276526 0.2175780114645457 0.8277579183628525 1.0 1.0 19 O43657 1 +Regulation of histone phosphorylation 0.3873033701889941 0.2169436472921633 0.828252261898262 1.0 1.0 5 Q5MIZ7 1 +Multivesicular body organization 0.3693911798095824 0.2158192564349986 0.8291286375616429 1.0 1.0 13 Q9UQN3,Q9H9H4 2 +Negative regulation of protein polymerization 0.3214934117355953 0.2157923939159835 0.8291495774220705 1.0 1.0 27 Q9NUQ9,P07737,Q15691,Q9Y6D6,P45880,P04350,P16949,O94813,Q9NYL9 9 +Ventricular septum morphogenesis 0.4064315324340916 0.2142363847972356 0.8303627237350417 1.0 1.0 4 Q9Y6N7 1 +Embryonic hemopoiesis 0.3862026485987037 0.2139870816318519 0.8305571312241045 1.0 1.0 5 Q15648,Q13188,Q9H6E4,Q13043 4 +Negative regulation of protein containing complex assembly 0.3022003555134322 0.210797883778975 0.8330449899416814 1.0 1.0 42 P45880,P04062 2 +Response to molecule of bacterial origin 0.2917018603221341 0.2106097889457557 0.8331917731698737 1.0 1.0 36 P30536,Q9UDY8,Q8IXJ6,Q8WTV0 4 +Vascular endothelial growth factor receptor signaling pathway 0.3670327867669596 0.2100883464362429 0.8335987207165225 1.0 1.0 9 Q16539 1 +Mature ribosome assembly 0.3846627656298099 0.2098823740941522 0.8337594792774701 1.0 1.0 5 Q9Y3A5,Q07021,O00571,P56537 4 +Glucose 6 phosphate metabolic process 0.3675471336176766 0.2079135169653971 0.8352964947846861 1.0 1.0 11 P52789,Q9NQ88,P11413 3 +Regulation of striated muscle cell differentiation 0.3674436004372295 0.2075667991019303 0.8355672302040249 1.0 1.0 11 Q16539,P67809,Q9BYT8 3 +Response to antibiotic 0.3646732429099937 0.206411578229126 0.8364694274465307 1.0 1.0 8 P62829,P07900,O60341,P50416,Q96KQ7,P61160,O95251 7 +Positive regulation of neuron apoptotic process 0.3670980192827862 0.2063363471371515 0.8365281884332487 1.0 1.0 12 O95831,P42575,Q15375,P49427 4 +Apoptotic process involved in development 0.4022778495188253 0.2043708674329649 0.8380636941454187 1.0 1.0 4 P30154 1 +Receptor clustering 0.3660608235966792 0.2039900199079808 0.8383612978981636 1.0 1.0 13 P57105 1 +Cell proliferation in forebrain 0.3823013129142685 0.2036594358652359 0.8386196432595494 1.0 1.0 5 Q86VS8,Q96N67 2 +Dedifferentiation 0.6603076923076945 0.202029145818713 0.839893938890504 1.0 1.0 2 Q14103 1 +Response to peptide hormone 0.3709450841614677 0.201689097586467 0.8401597863163899 1.0 1.0 84 P43490,Q92572,P46108,P09960,Q709C8,Q96A49,P49770,Q16836,Q9UQB8,Q16539,Q15043,P16435,Q9Y5X3,P06400,P04083,Q9BSK2,Q6ZWJ1,Q9UI10,P40939,P42224,Q06481 21 +Negative regulation of phosphorylation 0.3331559410818841 0.2009919985921369 0.8407048306021401 1.0 1.0 61 Q99816,P04035,P06400,P10644,P63244,O95373,Q9NQ88,Q86XL3,P0DP25,P04062,Q5MIZ7,Q8IXJ6 12 +Negative regulation of fibroblast apoptotic process 0.53093259464451 0.200440061756275 0.8411364304085021 1.0 1.0 3 Q9UEE9,Q9HCK8 2 +Intraciliary transport involved in cilium assembly 0.6590769230769269 0.1999782697492766 0.8414975760702903 1.0 1.0 2 A0AVF1 1 +Glycosylation 0.3176455480643049 0.1989693448077587 0.8422867244276719 1.0 1.0 52 Q6ZXV5,O15118,O75503,Q9BXS4,P04062 5 +Toll like receptor signaling pathway 0.3648254882807211 0.1985745261091213 0.8425955819780822 1.0 1.0 12 Q06481,P41440 2 +Actin cytoskeleton reorganization 0.311985997597591 0.1978410493730149 0.8431694281361288 1.0 1.0 28 P52565,Q8NE86,P11233,Q9UQB8,Q9Y624,P04083,O14786 7 +Establishment of cell polarity 0.296801162681594 0.1977322663458404 0.8432545432131255 1.0 1.0 40 P53350,Q9NUQ9,Q14254,P08238,P07900,Q92538,P46108,P63244,Q14517,Q4VCS5,P46109,Q96EA4 12 +Regulation of smoothened signaling pathway 0.3638553767074789 0.1972875661036051 0.8436025089432133 1.0 1.0 10 P06400,Q6PHR2,P63244 3 +Formation of translation preinitiation complex 0.361538889926603 0.1968407985816048 0.8439521230057754 1.0 1.0 8 P55010 1 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3784273724162369 0.1936407326002096 0.8464572017965386 1.0 1.0 5 P63244 1 +Nuclear pore complex assembly 0.3609166483548325 0.1909346182847938 0.848576817610575 1.0 1.0 9 Q9BTX1 1 +Regulation of vitamin metabolic process 0.6529230769230797 0.1899428403452899 0.8493539217616604 1.0 1.0 2 Q9NPF0 1 +Negative regulation of hormone metabolic process 0.6529230769230767 0.1899428403452857 0.8493539217616637 1.0 1.0 2 P05023 1 +Mitotic g2 m transition checkpoint 0.3548711718649341 0.1898916570645957 0.8493940302221303 1.0 1.0 18 P53350,Q6NUQ1,Q9NWV8,Q9Y619 4 +Cellular response to testosterone stimulus 0.5250846414281359 0.1893437038621169 0.8498234440506831 1.0 1.0 3 Q13772,O75116 2 +Maintenance of blood brain barrier 0.3766553741915706 0.1891374699356878 0.8499850746912359 1.0 1.0 5 P18206,Q07157,Q9Y624,P55011 4 +Positive regulation of metallopeptidase activity 0.6523076923076967 0.1889593853201996 0.8501246490919219 1.0 1.0 2 Q96HY6 1 +Eating behavior 0.6523076923076949 0.1889593853201965 0.8501246490919243 1.0 1.0 2 P50416 1 +Fatty acid alpha oxidation 0.3949276626066405 0.187558362769206 0.8512228685899303 1.0 1.0 4 A1L0T0 1 +Regulation of mrna binding 0.3757314444102281 0.1868093718319396 0.8518100986148662 1.0 1.0 5 Q86X55,O15371,P60228,Q04637 4 +Mitochondrial fragmentation involved in apoptotic process 0.3754693409069493 0.1861514243609713 0.8523260157992867 1.0 1.0 5 Q9Y3D6,O00429 2 +Intestinal epithelial cell development 0.523046466981345 0.185571637221476 0.852780697408861 1.0 1.0 3 Q9NQ88 1 +Lipid catabolic process 0.3569734238449006 0.1842275359601393 0.8538349585997498 1.0 1.0 77 O75874,P06280,Q8NCC3,Q13510,P04066,P17900,Q8NCG7,P06865,P23786,P40939,Q8NHP8,P50897,P04062,Q8WTV0,Q8IXJ6,O95470 16 +Single fertilization 0.3318566452278755 0.1837136845244676 0.8542380729350083 1.0 1.0 24 Q05086,P45880,Q9GZP4 3 +Glycoprotein biosynthetic process 0.3237881017206396 0.183549674224787 0.8543667463565208 1.0 1.0 57 Q6ZXV5,O15118,Q9BXS4,Q92542,Q9NQX7,Q8NCH0,Q8N6G5 7 +Dna methylation involved in gamete generation 0.5218849379131049 0.1834440866066979 0.8544495866190636 1.0 1.0 3 Q9Y2W6 1 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3566542351445019 0.1813899439325668 0.8560615115342955 1.0 1.0 16 O95817,P26583,P21359,P09601 4 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.6470769230769261 0.1807475818653757 0.8565657089022931 1.0 1.0 2 Q9UNS2 1 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3564707401362136 0.1807071040382738 0.8565974823767863 1.0 1.0 16 Q9UQ84,Q96FV9,P13051 3 +Somatic diversification of immunoglobulins involved in immune response 0.3564707401362136 0.1807071040382738 0.8565974823767863 1.0 1.0 16 Q9UQ84,Q96FV9,P13051 3 +Regulation of cholesterol metabolic process 0.3729830060676036 0.1799651486047352 0.8571799288237572 1.0 1.0 5 P34913 1 +Vascular associated smooth muscle cell migration 0.5198522622345381 0.179759533610251 0.8573413535392549 1.0 1.0 3 Q96N67,P09493 2 +Activation of phospholipase d activity 0.519852262234538 0.179759533610251 0.8573413535392549 1.0 1.0 3 P40616,P18085 2 +Regulation of cyclin dependent protein kinase activity 0.3557394753024082 0.1779927117618819 0.8587286995185262 1.0 1.0 16 P53350,O75832,Q16543,Q9P287,P08238,O95373 6 +Mitochondrial fusion 0.3575063279757008 0.1762779845074239 0.8600755570109713 1.0 1.0 14 Q99536,O60313,Q9Y3D6 3 +Mammary gland epithelial cell proliferation 0.3525371430883423 0.175723492962207 0.8605111777778072 1.0 1.0 7 Q86VI3 1 +Negative regulation of ion transmembrane transport 0.3528396056267839 0.1735347752527582 0.8622310958171475 1.0 1.0 17 P21796 1 +Fibroblast proliferation 0.3563353225960689 0.1722226628904585 0.8632624816646082 1.0 1.0 14 P11802,O75844,P14635,P21359,P14174 5 +Glycoprotein metabolic process 0.3352720742376083 0.1712333013292824 0.8640403234985627 1.0 1.0 65 Q9H0U4,O00754,Q6ZXV5,Q93063,O15118,Q9BXS4,P35610,Q9HC07,Q92542,Q9NQX7,O00462,Q8NCH0,Q8N6G5,O43505 14 +Positive regulation of fatty acid beta oxidation 0.6403076923076958 0.170512438784395 0.8646071528729826 1.0 1.0 2 P50416 1 +Positive regulation of fatty acid oxidation 0.6403076923076958 0.170512438784395 0.8646071528729826 1.0 1.0 2 P50416 1 +Lysine catabolic process 0.5141413711377654 0.1696713908162408 0.8652685746227102 1.0 1.0 3 Q9BQT8 1 +Positive regulation of multicellular organism growth 0.3495596782257401 0.1673979742201692 0.8670569190248871 1.0 1.0 7 Q9HCL2 1 +Regulation of renal system process 0.6359999999999871 0.1642290516044892 0.8695508317212013 1.0 1.0 2 Q9Y5X3 1 +Renal sodium excretion 0.6359999999999871 0.1642290516044892 0.8695508317212013 1.0 1.0 2 Q9Y5X3 1 +Positive regulation of renal sodium excretion 0.6359999999999871 0.1642290516044892 0.8695508317212013 1.0 1.0 2 Q9Y5X3 1 +Renal tubular secretion 0.6359999999999871 0.1642290516044892 0.8695508317212013 1.0 1.0 2 Q9Y5X3 1 +Regulation of excretion 0.6359999999999871 0.1642290516044892 0.8695508317212013 1.0 1.0 2 Q9Y5X3 1 +Tricarboxylic acid cycle 0.3395674865677339 0.1628224273728094 0.8706582494174249 1.0 1.0 21 P48735 1 +Proximal tubule development 0.5098508094751251 0.1623485670110159 0.8710313709903144 1.0 1.0 3 P35610 1 +Establishment of protein localization to endoplasmic reticulum 0.3357499549486111 0.1619242130315687 0.8713655351939049 1.0 1.0 22 Q9Y5M8,O43681,P46379,Q15629 4 +Collagen metabolic process 0.3512180080172866 0.1618938571467355 0.8713894402927542 1.0 1.0 9 Q9H267,P50454,O60568,Q92769,P05556,Q92791,P12955,Q32P28 8 +Negative regulation of proteolysis 0.3353127971281597 0.1608665656315202 0.8721984960526048 1.0 1.0 66 P19474,Q9NVX2,P49069,Q9BXS4,Q96K76,Q96HY6,Q9UL15,P30086,P16435,O00560,P46379,P78318,Q92530,Q92896,P04080,P05067,O15372,Q15392,Q06481 19 +Cellular response to extracellular stimulus 0.2964060290692882 0.1605771612146616 0.8724264441503267 1.0 1.0 43 Q9H773,P09601,P04062 3 +Modulation by host of symbiont catalytic activity 0.6332307692307567 0.160283936074509 0.872657412427716 1.0 1.0 2 Q9H1E3 1 +Exocytosis 0.3450177508171941 0.1598149065548945 0.8730268812792472 1.0 1.0 72 Q15907,Q99816,Q8IYI6,O15498,Q4J6C6,O43760,Q7L0J3,Q15833,O00560,P0DP25,P09601,Q9UPT5,P11279,P04083,Q7Z6M1 15 +Er overload response 0.3643363104404086 0.159235727581117 0.8734831564209926 1.0 1.0 5 Q96A33,Q9UM00,O76024,P49841 4 +Regulation of neuroblast proliferation 0.3643363104404039 0.1592357275811063 0.873483156421001 1.0 1.0 5 P35221,P21359,P35222,O60341 4 +Catechol containing compound metabolic process 0.3431916204559544 0.1567923519773792 0.8754085005379353 1.0 1.0 6 P58546,P21964,Q99497,P05091,P00492 5 +Positive regulation of lymphocyte mediated immunity 0.3440553561894534 0.1567395665147667 0.8754501028892536 1.0 1.0 19 P04439,Q9BY67,P01889,P11279,Q9UDY8,Q9NQT5 6 +Regulation of fatty acid transport 0.3632567105462972 0.1567340392072493 0.8754544592030713 1.0 1.0 5 Q9Y3D6 1 +Positive regulation of nad p h oxidase activity 0.5063096337334605 0.1564705228614498 0.8756621523856156 1.0 1.0 3 P04899,P08754 2 +Regulation of nad p h oxidase activity 0.5063096337334605 0.1564705228614498 0.8756621523856156 1.0 1.0 3 P04899,P08754 2 +Negative regulation of inclusion body assembly 0.5059593332566221 0.1558972016260872 0.8761140511193795 1.0 1.0 3 P25685 1 +L serine transport 0.629846153846158 0.1555620045211978 0.8763782762533048 1.0 1.0 2 Q15758 1 +Wound healing 0.3310578063367858 0.1548742349190068 0.8769204660925847 1.0 1.0 64 Q6UWU4,P53582,Q9UQN3,P46108,P42785,P09601,Q8WTV0,P04083,Q9BWH2 9 +Mitochondrial proton transporting atp synthase complex assembly 0.6289230769230745 0.1542932343460116 0.8773785316494784 1.0 1.0 2 Q15070 1 +Iron ion transport 0.3504266073372714 0.1531976289644513 0.8782424274143339 1.0 1.0 11 O15173,Q15907,Q15043,P02792 4 +Response to interleukin 4 0.3455533532177062 0.1506525469404986 0.8802498079307108 1.0 1.0 8 P49327,P11802,P33993 3 +Pointed end actin filament capping 0.6258461538461582 0.1501227598239211 0.8806677637250662 1.0 1.0 2 Q9NYL9 1 +Odontoblast differentiation 0.6249230769230815 0.1488892140925364 0.8816410522554197 1.0 1.0 2 P07437 1 +Response to insecticide 0.6249230769230814 0.1488892140925364 0.8816410522554197 1.0 1.0 2 P36551 1 +Ensheathment of neurons 0.3143819532860186 0.1471722093819989 0.8829960954161771 1.0 1.0 26 Q9UI10,P49770,P53634,Q92542,Q8IXJ6 5 +Vasculogenesis 0.3457804336315216 0.1463523684674809 0.8836432268064105 1.0 1.0 9 Q4VCS5,O95470 2 +Regulation of protein folding 0.374781042095892 0.1457910642828042 0.8840863302007425 1.0 1.0 4 O14737 1 +Response to dsrna 0.3476286264783267 0.1429337078548139 0.8863425368662785 1.0 1.0 14 Q9NUD5,P41440 2 +Regulation of lipid kinase activity 0.3425305064517562 0.1424287144680514 0.8867413827183594 1.0 1.0 8 P06400,Q05639 2 +Negative regulation of epithelial cell proliferation 0.3457955408500658 0.1421972260293216 0.8869242228340133 1.0 1.0 16 Q9Y6N7,Q9Y366,P57105,P06400 4 +Neurotransmitter gated ion channel clustering 0.6193846153846202 0.1416578347698673 0.8873502819599461 1.0 1.0 2 Q9NQX3 1 +Magnesium ion homeostasis 0.4967682363804292 0.141377882596909 0.8875714258928662 1.0 1.0 3 Q6P4Q7,Q8NE01 2 +Glucocorticoid metabolic process 0.3723911457710153 0.1412614060321884 0.8876634373512957 1.0 1.0 4 Q04917,P05023 2 +Cell cell junction maintenance 0.618461538461543 0.1404808268116833 0.8882801002512735 1.0 1.0 2 Q07157 1 +Adherens junction maintenance 0.618461538461543 0.1404808268116833 0.8882801002512735 1.0 1.0 2 Q07157 1 +Sertoli cell differentiation 0.4955370883348766 0.1395094361503898 0.8890475998883511 1.0 1.0 3 Q14151,P51659 2 +Negative regulation of ion transport 0.3417165323562887 0.1390479575191144 0.8894122524852652 1.0 1.0 18 P21796 1 +Positive regulation of protein k63 linked ubiquitination 0.6172307692307591 0.1389239789806313 0.8895102222169808 1.0 1.0 2 P61088 1 +Response to nutrient 0.3072156882240802 0.1385491560428886 0.8898064232746072 1.0 1.0 27 O43768,P16435,P30536,Q96C86,P42224,P04818,P09601 7 +Axoneme assembly 0.4937855139112457 0.1368821842515461 0.8911239211814281 1.0 1.0 3 Q15555 1 +Regulation of mitotic recombination 0.369458128078807 0.1358261948526578 0.8919586824637453 1.0 1.0 4 P18074,P49959,Q15554 3 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.3348928486608666 0.1356567577671565 0.8920926339180388 1.0 1.0 6 P30154,P21359 2 +Organic hydroxy compound catabolic process 0.3438206876765163 0.1353422642874181 0.8923412704025826 1.0 1.0 16 Q10713,Q8WTV0 2 +Regulation of cell division 0.2734083190522589 0.1353392730885757 0.8923436352756358 1.0 1.0 32 P67809,Q8WYP5,P0DP25,Q9H0H5,Q8IXJ6 5 +Vascular endothelial growth factor signaling pathway 0.4924397891890769 0.1348883920364601 0.8927001174822697 1.0 1.0 3 O14786 1 +Regulation of protein maturation 0.3449240321030392 0.1347204727187525 0.8928328858668808 1.0 1.0 12 Q9BXS4,Q92896 2 +Regulation of t cell proliferation 0.3422176836096929 0.134434752783491 0.8930588022988393 1.0 1.0 17 P30825,P49366,P04439,P10644,P04083,Q9HCL2 6 +Late endosome to golgi transport 0.4918436441982192 0.1340120124464895 0.893393075562072 1.0 1.0 3 O60493,Q8IWJ2 2 +Negative regulation of notch signaling pathway 0.4915785759355069 0.1336236918866859 0.8937001487806004 1.0 1.0 3 Q86U44 1 +Establishment of golgi localization 0.4912280701754429 0.1331114826063071 0.8941052141549461 1.0 1.0 3 P63104,P60953 2 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.4907718997636482 0.1324470358854394 0.8946307130875422 1.0 1.0 3 Q13043 1 +Negative regulation of neuron projection development 0.3377510262800823 0.1322863707749784 0.8947577871789971 1.0 1.0 19 Q96G23,P31150,Q15375,Q05086,Q9NQX7,O14786,Q8N0X7 7 +Positive regulation of striated muscle contraction 0.6113846153846209 0.1317231294534603 0.8952032902671048 1.0 1.0 2 P05023 1 +Regulation of skeletal muscle contraction by calcium ion signaling 0.6113846153846193 0.1317231294534589 0.8952032902671059 1.0 1.0 2 P28161 1 +Artery development 0.3420371649295274 0.131714531580185 0.8952100911238847 1.0 1.0 10 Q9Y6N7,O14786,P21359,Q96AY3 4 +Regulation of endoplasmic reticulum unfolded protein response 0.3360683743297109 0.1316288335944923 0.8952778780436295 1.0 1.0 7 P63244,Q92905 2 +Flavin containing compound metabolic process 0.6107692307692363 0.1309837238508062 0.8957881829529435 1.0 1.0 2 Q8NFF5 1 +Positive regulation of reactive oxygen species metabolic process 0.3435290057430185 0.1296836976295815 0.8968166810444405 1.0 1.0 14 P30536,P00403 2 +Regulation of ras protein signal transduction 0.2757969051121488 0.1282542302222435 0.8979477848774331 1.0 1.0 34 P52565,Q9Y6D6,Q8N6T3,Q9Y6N7,O75955,Q92538,P46108,P50570,Q5HYI8,P16949,Q9Y624,Q04721,P41440,O14786,Q15555 15 +Positive regulation of histone ubiquitination 0.3651477832512201 0.1280862993508421 0.8980806782707478 1.0 1.0 4 Q6PD62,Q5VTR2,O75150 3 +Positive regulation of cysteine type endopeptidase activity 0.2930088654940284 0.1267786678080422 0.8991155801055062 1.0 1.0 29 Q9Y3D6,Q9P0J0,P63244,Q9BXK5,Q9UDY8,Q96A26,O14737 7 +Dna damage response signal transduction resulting in transcription 0.3642241379310262 0.1264660724839531 0.89936300361725 1.0 1.0 4 Q9UNS2,O96017,P61254 3 +Response to bacterium 0.314824238497722 0.1262385020638863 0.8995431348983023 1.0 1.0 57 P30536,P01889,Q9UQB8,Q9NZ08,Q8WTV0,Q9BTY2,Q9UDY8,Q8IXJ6 8 +Inner ear receptor cell development 0.3360721182506045 0.1254207968333665 0.9001904246204357 1.0 1.0 8 P54802 1 +Regulation of peptidyl tyrosine phosphorylation 0.3148905356946315 0.1252407549564287 0.9003329534394302 1.0 1.0 25 Q99816,P05067,P63244,Q15375,Q9H223,O14786 6 +Embryonic placenta morphogenesis 0.4850723299476804 0.1243519537710583 0.9010366133247114 1.0 1.0 3 P62993,Q15363 2 +Regulation of peptide transport 0.3190421286618646 0.1235770406299088 0.9016501720440244 1.0 1.0 24 O43768,Q6ZWJ1,Q8N183,Q8NE86,P30626,P40939,P00367 7 +Artery morphogenesis 0.3477806144451654 0.1230216819814692 0.9020899286417654 1.0 1.0 5 O14786,Q96AY3 2 +Regulation of rac protein signal transduction 0.3289450300289807 0.1212621282374448 0.9034834158943852 1.0 1.0 6 P46108 1 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.3382554482178911 0.1212593557812116 0.9034856117905036 1.0 1.0 10 O43681,P46379 2 +Response to cocaine 0.3317588556121502 0.1208950827469393 0.9037741370036372 1.0 1.0 7 P50570,Q05086 2 +Imp salvage 0.6018461538461599 0.1206559988920581 0.9039635120889986 1.0 1.0 2 P07741 1 +Basement membrane assembly 0.4823022468451877 0.1205552773818254 0.9040432938700652 1.0 1.0 3 O60568,O75122 2 +Free ubiquitin chain polymerization 0.4820227679455454 0.1201772006953371 0.9043427780741125 1.0 1.0 3 Q13049 1 +Fatty acid derivative metabolic process 0.3292137712412794 0.1199798239981284 0.904499130608368 1.0 1.0 21 P50897,Q9UMR5 2 +Negative regulation of mitochondrion organization 0.3389742053764107 0.1188879908316919 0.9053640962071244 1.0 1.0 16 Q99536,O60313,P30536 3 +Embryonic skeletal joint morphogenesis 0.6000000000000064 0.1186104144547944 0.9055840140609686 1.0 1.0 2 O95747 1 +Lung associated mesenchyme development 0.6000000000000063 0.1186104144547944 0.9055840140609686 1.0 1.0 2 Q13308 1 +Nephron tubule formation 0.6000000000000064 0.1186104144547944 0.9055840140609686 1.0 1.0 2 O95747 1 +Embryonic skeletal joint development 0.6000000000000064 0.1186104144547944 0.9055840140609686 1.0 1.0 2 O95747 1 +Mesenchymal stem cell differentiation 0.6000000000000063 0.1186104144547944 0.9055840140609686 1.0 1.0 2 P49841 1 +Canonical wnt signaling pathway involved in osteoblast differentiation 0.6000000000000063 0.1186104144547944 0.9055840140609686 1.0 1.0 2 P49841 1 +Limb joint morphogenesis 0.6000000000000064 0.1186104144547944 0.9055840140609686 1.0 1.0 2 O95747 1 +Epidermis morphogenesis 0.5999999999999936 0.1186104144547806 0.9055840140609794 1.0 1.0 2 O60568 1 +Gamma aminobutyric acid signaling pathway 0.599692307692314 0.118272496676917 0.905851748893176 1.0 1.0 2 P04899 1 +Photoreceptor cell maintenance 0.4804133824555179 0.1180177400842894 0.9060536015603332 1.0 1.0 3 Q15555 1 +Retina homeostasis 0.4804133824555179 0.1180177400842894 0.9060536015603332 1.0 1.0 3 Q15555 1 +Positive regulation of lipid localization 0.3392567183719598 0.1179574822349751 0.906101346875574 1.0 1.0 12 Q8WTV0 1 +Protein targeting 0.4128943865488935 0.1179266651945209 0.9061257648930128 1.0 1.0 120 P43307,Q9Y3D6,P30536,Q99797,P55786,Q9NS69,Q99595,P20645,Q709C8,Q9H0F7,Q15629,P27105,O14737,O14925,P57105,O60725,Q9Y584,Q9H9H4,Q9P0J0,Q14108,Q8N4H5,O00560,P46379,O43615,Q6ZWJ1,Q10713,O95429,Q16543,O43681,Q7L5D6,Q9Y5M8,Q9Y5Y5,Q9NQG6,P13473 34 +Very long chain fatty acid catabolic process 0.3592088399631515 0.1179040875036586 0.9061436544819156 1.0 1.0 4 O14975 1 +Regulation of ubiquitin protein transferase activity 0.3083339815062742 0.1173181742794257 0.9066079234891916 1.0 1.0 26 P53350,P61088,P62841,Q8IWE4,Q9BTE7,P60866,Q92564,Q9UL15 8 +Positive regulation of protein deubiquitination 0.4798399507540827 0.1172555916941912 0.9066575148969972 1.0 1.0 3 P55072,Q15020 2 +Negative regulation of protein localization 0.298040416624531 0.1164606034164178 0.907287507503436 1.0 1.0 48 Q13438,P31150,P04035,O95429,Q10713,Q8N183,Q16836,P40939,Q9BXS4,Q16850 10 +Ribosomal small subunit export from nucleus 0.3323627934745158 0.1160040200320072 0.9076493557831868 1.0 1.0 8 Q96GA3,Q9BVS4,P62841 3 +Regulation of microtubule based movement 0.3577907531973789 0.1155552114827804 0.9080050610844064 1.0 1.0 4 P11279 1 +Asparagine metabolic process 0.3575836909690028 0.1152148914993608 0.9082747955704872 1.0 1.0 4 Q9NWL6 1 +Regulation of interleukin 1 mediated signaling pathway 0.5956923076923142 0.113957488541975 0.9092714930695992 1.0 1.0 2 Q86Y07 1 +Renal tubule development 0.3287852995781947 0.1136883367905272 0.9094848584653484 1.0 1.0 7 P35610,P42224 2 +Regulation of mitotic cytokinesis 0.5953846153846221 0.1136315342950406 0.9095298884960508 1.0 1.0 2 P37198 1 +Dopamine metabolic process 0.3430859254696647 0.1135978282492937 0.9095566090136497 1.0 1.0 5 P05091,P21964,Q99497,P00492 4 +5 phosphoribose 1 diphosphate metabolic process 0.4764542936288135 0.1128333588997965 0.910162670637455 1.0 1.0 3 P06737,Q14558 2 +Positive regulation of dendritic cell differentiation 0.5938461538461605 0.112014486047452 0.9108119206533044 1.0 1.0 2 P09429 1 +Regulation of protein tyrosine phosphatase activity 0.5938461538461605 0.112014486047452 0.9108119206533044 1.0 1.0 2 P04899 1 +Establishment of planar polarity of embryonic epithelium 0.4755309325946487 0.1116502640216787 0.9111007162166276 1.0 1.0 3 P43034,Q13308 2 +Keratinocyte proliferation 0.3247587083131232 0.1115141926047982 0.9112086117226345 1.0 1.0 6 Q6ZWJ1,Q04721 2 +Regulation of keratinocyte proliferation 0.3247587083131232 0.1115141926047982 0.9112086117226345 1.0 1.0 6 Q6ZWJ1,Q04721 2 +Roundabout signaling pathway 0.474688715431339 0.1105796896070587 0.9119496540418344 1.0 1.0 3 Q9Y6N7 1 +Cellular response to interferon beta 0.3274287528913741 0.1104551062551604 0.9120484519650204 1.0 1.0 7 Q9P0J0,P49427 2 +Response to interferon beta 0.3274287528913741 0.1104551062551604 0.9120484519650204 1.0 1.0 7 Q9P0J0,P49427 2 +Respiratory chain complex iv assembly 0.3543719211822537 0.1100224996367176 0.9123915311070864 1.0 1.0 4 Q15070,Q9Y2R0,O75880 3 +Mitochondrial cytochrome c oxidase assembly 0.3543719211822537 0.1100224996367176 0.9123915311070864 1.0 1.0 4 Q15070,Q9Y2R0,O75880 3 +Neuron cellular homeostasis 0.3270279855404561 0.1095064662870511 0.9128007932594592 1.0 1.0 7 Q9UQN3 1 +Coronary vasculature development 0.3264080027804818 0.1080448354202383 0.9139601268309054 1.0 1.0 7 O14786 1 +Negative regulation of i kappab kinase nf kappab signaling 0.3231669747381466 0.1078917059585764 0.914081596402384 1.0 1.0 6 Q14694,Q86UT6,O60826,Q13547,P42224 5 +Regulation of tumor necrosis factor mediated signaling pathway 0.3231669747381448 0.1078917059585723 0.9140815964023874 1.0 1.0 6 O14920,P0DMV9,Q99829,Q13049,P61086 5 +Glutamate biosynthetic process 0.4723933925580493 0.1077033011580989 0.9142310508035028 1.0 1.0 3 P00367 1 +Kidney epithelium development 0.3345880123520879 0.1075440691660819 0.9143573658841496 1.0 1.0 11 P42224,Q04721,P35610,Q15375 4 +Regulation of small gtpase mediated signal transduction 0.2912278948701919 0.1059855861416445 0.9155937883617844 1.0 1.0 45 P46108,P50570,P16949,Q9Y624,P52565,Q8N6T3,Q92538,Q4VCS5,Q04721,P41440,Q9H0H5,Q15555,Q9NUQ9,O14786,O94813,Q9Y6D6,Q9Y6N7,O75955,Q5HYI8 19 +Schwann cell differentiation 0.3280961297576026 0.105494083013215 0.9159837648636672 1.0 1.0 8 Q8IXJ6,P06493 2 +Negative regulation of sequestering of triglyceride 0.5873846153846226 0.1054525690629366 0.9160167044727812 1.0 1.0 2 Q96AD5 1 +Collagen biosynthetic process 0.3506773399014656 0.104249561943579 0.9169713034648548 1.0 1.0 4 P50454,Q92791,Q92769 3 +Mrna modification 0.3352943548848908 0.10415339053622 0.9170476216895732 1.0 1.0 14 Q9UJA5,Q9UBS4 2 +Positive regulation of extrinsic apoptotic signaling pathway 0.3350070414387782 0.1039858734935853 0.9171805591101092 1.0 1.0 13 Q9NQX7,P30153,P30154,P21359 4 +Intestinal epithelial cell differentiation 0.3502669675878279 0.1036214911995837 0.9174697319624764 1.0 1.0 4 Q9NQ88 1 +Regulation of calcium ion transmembrane transport 0.3299448146148566 0.1033553048713447 0.9176809836523974 1.0 1.0 19 P21796 1 +Response to peptide 0.3725154135866493 0.1031408443163983 0.917851188788311 1.0 1.0 95 P43490,Q92572,P46108,P09960,P33527,Q709C8,Q96A49,P49770,Q16836,Q9UQB8,Q16539,Q15043,P16435,Q9Y5X3,P06400,P04083,Q9BSK2,Q6ZWJ1,Q9UI10,P05067,P40939,P42224,Q06481 23 +Cilium organization 0.3110372462385495 0.1029705443780199 0.9179863488386002 1.0 1.0 57 Q15691,Q9H223,Q9Y496,Q9Y366,Q15019,Q92538,Q9H4M9,Q9Y277,Q66K14,P50570,Q8IVD9,Q8TC07,Q9H0F7,O43805,P61160,Q15555,Q96EX3,A6NIH7 18 +Regulation of skeletal muscle cell differentiation 0.3494458128078713 0.1023725949881689 0.9184609353986004 1.0 1.0 4 Q92841,Q9BRT2,Q9BYT8 3 +Positive regulation of fat cell differentiation 0.3267393498616086 0.1022246807241734 0.918578337986358 1.0 1.0 8 Q16539 1 +Fc receptor mediated stimulatory signaling pathway 0.3201912695839294 0.101244235699091 0.9193565820905274 1.0 1.0 6 Q06481 1 +Regulation of ruffle assembly 0.3262925475806593 0.1011557468267014 0.9194268253769222 1.0 1.0 8 P35080,P84095,P07737 3 +Fc gamma receptor signaling pathway 0.3363101045770793 0.1006604427144331 0.9198200139622206 1.0 1.0 5 Q06481 1 +Long chain fatty acyl coa metabolic process 0.3304078572293545 0.1004600883140294 0.919979067404804 1.0 1.0 10 Q9NZ01,Q9UKU0 2 +Electron transport chain 0.3239029039474038 0.1003359370929014 0.9200776277610272 1.0 1.0 65 O75380,P00403,O43676,Q9UDW1,O15460,O95168,O95182,P04062,O75306 9 +Response to potassium ion 0.5809230769230844 0.0992561012449345 0.9209349323705628 1.0 1.0 2 P55011 1 +Cellular response to potassium ion 0.5809230769230844 0.0992561012449345 0.9209349323705628 1.0 1.0 2 P55011 1 +Neuromuscular junction development 0.3298532810030554 0.0990366080783886 0.9211092039259284 1.0 1.0 10 P05067,P46109 2 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2877288550759074 0.0979463527264327 0.9219748927583552 1.0 1.0 29 O60506,Q969T7,P67809,Q9NQT5 4 +Cardiac septum morphogenesis 0.3242613998213896 0.0963447302293081 0.9232467867092482 1.0 1.0 8 Q9Y6N7,O14786,Q04721 3 +Response to oxygen levels 0.3198880270087399 0.0960854028296028 0.9234527445167792 1.0 1.0 63 Q8N511,P55786,P30519,Q9Y487,Q15904,P52789,P09601,Q96A26,O75306,Q8IXJ6 10 +Meiotic cell cycle checkpoint signaling 0.4622960911049603 0.095759005922485 0.9237119762165796 1.0 1.0 3 P33981,Q15645 2 +Negative regulation of epithelial cell differentiation 0.3430805091253026 0.093045868892524 0.9258671211468724 1.0 1.0 4 P42224 1 +Positive regulation of notch signaling pathway 0.3430415098111907 0.0929906492997627 0.9259109898117276 1.0 1.0 4 Q9Y6N7,Q8NBL1 2 +Voluntary musculoskeletal movement 0.3429802955664953 0.0929040223299539 0.9259798102136244 1.0 1.0 4 P78559,P18887,P42345 3 +Response to corticosteroid 0.2980542088946453 0.0924963067186633 0.9263037254548624 1.0 1.0 27 P04062,P0DP25,P16278 3 +Protein containing complex localization 0.2871860975288602 0.0917551822388212 0.9268925531768248 1.0 1.0 44 O43805,Q96EX3,P57105 3 +Regulation of protein localization to membrane 0.2871087275560758 0.0912871263713599 0.9272644469439224 1.0 1.0 44 Q9Y3D6,P63244,Q9BXS4,Q14651,Q9UNK0,P46109,Q9NQG6,P27105,O14737 9 +Osteoclast differentiation 0.3294282424794914 0.0881306021292469 0.9297728740211236 1.0 1.0 13 Q15904 1 +Protein exit from endoplasmic reticulum 0.318044654809025 0.0879549725459123 0.9299124640856676 1.0 1.0 22 Q13438,O15260,Q9UBV2,O15027,Q9NR31,Q9Y385,P49257 7 +Bile acid metabolic process 0.3231967450328629 0.08778898384727 0.9300443935751804 1.0 1.0 9 O15118 1 +Vesicle uncoating 0.3389778325123052 0.0873641367791542 0.9303820750528372 1.0 1.0 4 P11142,Q9UN37,Q99961 3 +Cellular response to virus 0.3105360985321551 0.0863315419430015 0.9312028652253416 1.0 1.0 24 Q16539,Q9NUD5,O43657 3 +Chromosome organization involved in meiotic cell cycle 0.3251317291910969 0.0862890203514079 0.9312366664116374 1.0 1.0 19 P46379 1 +Nephron epithelium development 0.319353330368499 0.0850478856677021 0.9322233213279204 1.0 1.0 8 P35610,P42224 2 +Centromere complex assembly 0.3239818829802637 0.0843462515037553 0.9327811400085608 1.0 1.0 10 P49321 1 +Nls bearing protein import into nucleus 0.3188869707481094 0.0839987481806349 0.9330574270596396 1.0 1.0 8 Q8NFH5 1 +Tangential migration from the subventricular zone to the olfactory bulb 0.4498977683859514 0.0826339515744162 0.9341426041323218 1.0 1.0 3 Q9Y6N7 1 +Hydrogen peroxide biosynthetic process 0.4494293504037492 0.0821704876182126 0.9345111415301623 1.0 1.0 3 P00403 1 +Morphogenesis of an endothelium 0.5606153846153936 0.0820666301376044 0.9345937288783042 1.0 1.0 2 P35222 1 +Positive regulation of megakaryocyte differentiation 0.4483731691901182 0.0811339759891306 0.9353354058135812 1.0 1.0 3 Q9GZP4 1 +Receptor internalization 0.3215382628969028 0.0808594061684092 0.9355537633941532 1.0 1.0 20 O75955,O00560,P41440 3 +Positive regulation of intracellular protein transport 0.3039926815109445 0.0808449814305562 0.9355652351126796 1.0 1.0 55 Q9C0E2,Q9Y3D6,Q9Y282,P08238,Q9NQG6,P55786,O00459,Q05D32,O95817,Q9NR31,Q16539,O94766,P27105,O14737 14 +Cerebral cortex neuron differentiation 0.3322044334975289 0.0785402619579984 0.9373983047070856 1.0 1.0 4 P43034,P50542,P00492 3 +Positive regulation of wound healing spreading of epidermal cells 0.4453678054786132 0.0782485911647447 0.9376303103157526 1.0 1.0 3 Q96AC1,P42345 2 +Deoxyribonucleoside monophosphate biosynthetic process 0.3128330255344824 0.0778552675414916 0.937943182681732 1.0 1.0 7 P27707 1 +Neurotransmitter reuptake 0.3315886699507277 0.077772035468198 0.9380093915181552 1.0 1.0 4 P05556,Q99497,O14656 3 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.3230674468740342 0.0776388385752521 0.938115346892715 1.0 1.0 5 P61086,Q13049,P0DMV9,Q99829 4 +Plasma membrane tubulation 0.3312807881773273 0.077390024328947 0.9383132764152512 1.0 1.0 4 P50570,Q9Y5X1,Q9Y371 3 +Water soluble vitamin metabolic process 0.3205059758425109 0.0771787047061863 0.9384813822914122 1.0 1.0 20 Q9H2D1,P33527,P41440 3 +Positive regulation of fibroblast proliferation 0.3080979341240437 0.0759134910669185 0.9394879235135802 1.0 1.0 6 P14174,P11802 2 +Cellular response to thyroid hormone stimulus 0.4413359089351076 0.0745246487694039 0.9405929288163226 1.0 1.0 3 Q9H0E9 1 +Positive regulation of phagocytosis 0.3173207566980414 0.0741864884929878 0.9408619968446376 1.0 1.0 9 P50570,Q06481 2 +Regulation of heart rate by chemical signal 0.5495384615384713 0.0740745288832503 0.9409510825741978 1.0 1.0 2 P09493 1 +Protein acylation 0.3027798600985837 0.0737012261029307 0.9412481231553078 1.0 1.0 55 Q01105,Q86UY6,O75486,Q14CX7,O75844,P46379 6 +Negative regulation of leukocyte chemotaxis 0.4403922598642694 0.0736770982337134 0.9412673222124848 1.0 1.0 3 O94813 1 +Lung morphogenesis 0.3103235747303508 0.0726573437825972 0.9420787935177726 1.0 1.0 7 O60568,O95487,P28482,O00203,P35222,P60953 6 +Mitochondrial adp transmembrane transport 0.4392120652508513 0.0726297887186271 0.9421007213439574 1.0 1.0 3 P12235,P12236 2 +Regulation of osteoclast differentiation 0.3196630034221976 0.0722013010649483 0.9424417097779888 1.0 1.0 5 Q04721 1 +Protein o linked glycosylation 0.3240697522674632 0.0711019477934885 0.9433166179813968 1.0 1.0 15 O60568,Q6ZXV5,O60502,Q7Z4H8,Q10472,O43505,Q8NBL1 7 +Monovalent inorganic anion homeostasis 0.4370575561711342 0.0707540038514071 0.943593539636961 1.0 1.0 3 Q9BXP2,P55011 2 +Cellular senescence 0.3186532368093462 0.0706462053796551 0.9436793356790693 1.0 1.0 20 Q16539,O60313,P67809,O75844 4 +Negative regulation of kinase activity 0.2750063389597015 0.0701782201814776 0.9440518093547512 1.0 1.0 39 Q99816,P04035,P06400,P10644,O95373,P04062 6 +Negative regulation of t cell receptor signaling pathway 0.4358264081255823 0.0697029275852508 0.9444301115757032 1.0 1.0 3 P17931,P15311 2 +Negative regulation of antigen receptor mediated signaling pathway 0.4358264081255823 0.0697029275852508 0.9444301115757032 1.0 1.0 3 P17931,P15311 2 +Mrna 3 end processing by stem loop binding and cleavage 0.5427692307692381 0.0696415273864181 0.9444789830857968 1.0 1.0 2 Q9P2I0 1 +Farnesyl diphosphate metabolic process 0.4333220236579908 0.067611045932265 0.9460952621399804 1.0 1.0 3 P37268 1 +Macrophage apoptotic process 0.538461538461549 0.0669913264223399 0.9465886082018886 1.0 1.0 2 P42771 1 +Regulation of macrophage apoptotic process 0.538461538461549 0.0669913264223399 0.9465886082018886 1.0 1.0 2 P42771 1 +Chondrocyte development 0.5372307692307748 0.0662579232190085 0.9471724819811908 1.0 1.0 2 Q9NX62 1 +Regulation of cartilage development 0.3157693563573364 0.0662210929888826 0.9472018038551748 1.0 1.0 5 Q92896 1 +Regulation of chondrocyte differentiation 0.3157693563573364 0.0662210929888826 0.9472018038551748 1.0 1.0 5 Q92896 1 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.3136545066535592 0.0660488340539313 0.947338946352258 1.0 1.0 9 Q9Y6N7,Q14517 2 +Atp transport 0.3102416623463347 0.0653175518602952 0.947921167821862 1.0 1.0 8 Q86VD7,Q08722,Q6KCM7 3 +Regulation of mrna export from nucleus 0.3150600554357839 0.0651589595305029 0.9480474372038884 1.0 1.0 5 Q9ULX6,Q96ST2,Q7KZ85,Q08J23 4 +Activation of gtpase activity 0.3213148069637328 0.0651536102993454 0.9480516962227448 1.0 1.0 17 Q66K14,Q8TC07,P46108,P46109 4 +Myeloid cell development 0.3209786713637049 0.0641270092362765 0.9488690958412822 1.0 1.0 17 P05067 1 +Natural killer cell differentiation 0.4284395198522673 0.0637080824136962 0.9492026689876116 1.0 1.0 3 Q5HYI8,O95251 2 +Cell differentiation involved in embryonic placenta development 0.4284395198522667 0.0637080824136959 0.949202668987612 1.0 1.0 3 Q13188,Q13043 2 +U4 snrna 3 end processing 0.305701078582429 0.0633970959534087 0.9494502996948656 1.0 1.0 7 Q96B26,Q06265,Q15024,Q5RKV6,Q9NQT5,Q13868 6 +Aerobic respiration 0.3499599712676087 0.0632638897829374 0.9495563699175418 1.0 1.0 85 P14406,O75874,Q9BSK2,O75380,P00403,O43676,Q9UDW1,P24539,P48735,O75964,O95182,O95168,Q9Y6M9,O75306 14 +Defense response to gram positive bacterium 0.3181491670468692 0.0623763452227047 0.9502631320478148 1.0 1.0 4 P04439 1 +Negative regulation by host of viral transcription 0.3125962426855528 0.0615345063772659 0.9509335343488574 1.0 1.0 5 P17980,Q9H1E3,Q13547,P52926 4 +Positive regulation of striated muscle cell differentiation 0.3171687485202088 0.06135356653542 0.9510776311885932 1.0 1.0 4 Q16539 1 +Negative regulation of adenylate cyclase activity 0.528000000000008 0.0610840290262652 0.951292288388133 1.0 1.0 2 P04899 1 +Negative regulation of lyase activity 0.528000000000008 0.0610840290262652 0.951292288388133 1.0 1.0 2 P04899 1 +Negative regulation of golgi to plasma membrane protein transport 0.5261538461538513 0.0601165379563906 0.9520628184007054 1.0 1.0 2 P41240 1 +Immunological synapse formation 0.5249230769230838 0.0594836524928385 0.9525668858406572 1.0 1.0 2 P17931 1 +Copii coated vesicle cargo loading 0.3103275638586262 0.0588977977304865 0.9530335121649138 1.0 1.0 9 O95486,Q15437 2 +Chorion development 0.5221538461538577 0.0580945834794778 0.9536732888653976 1.0 1.0 2 Q9Y6R4 1 +Extraembryonic membrane development 0.5221538461538577 0.0580945834794778 0.9536732888653976 1.0 1.0 2 Q9Y6R4 1 +Labyrinthine layer morphogenesis 0.5221538461538567 0.0580945834794773 0.953673288865398 1.0 1.0 2 P62993 1 +Branching involved in labyrinthine layer morphogenesis 0.5221538461538567 0.0580945834794773 0.953673288865398 1.0 1.0 2 P62993 1 +Regulation of type b pancreatic cell development 0.5218461538461655 0.0579431961296245 0.9537938753649068 1.0 1.0 2 P49841 1 +Regulation of gene expression by genomic imprinting 0.3137315270935882 0.0578724153027837 0.9538502556840848 1.0 1.0 4 Q8NB78,P49711,P38398 3 +Biological process involved in intraspecies interaction between organisms 0.3137315270935856 0.0578724153027812 0.9538502556840868 1.0 1.0 4 Q96RL7,Q9HCK8,Q15154 3 +Negative regulation of peptidase activity 0.2677404324383071 0.0578619053597057 0.953858627376901 1.0 1.0 36 P04080,P30086,Q9NVX2,P05067,Q15392,Q06481,P78318,Q96K76,Q92530 9 +Positive regulation of myeloid leukocyte differentiation 0.3132977139788294 0.0574445200917393 0.95419109962522 1.0 1.0 4 P06400 1 +Negative regulation of bicellular tight junction assembly 0.4192059095106232 0.0569403351175759 0.9545927236394094 1.0 1.0 3 O14920,O75116 2 +Negative regulation of myosin light chain phosphatase activity 0.4192059095106232 0.0569403351175759 0.9545927236394094 1.0 1.0 3 O14920,O75116 2 +Regulation of myosin light chain phosphatase activity 0.4192059095106232 0.0569403351175759 0.9545927236394094 1.0 1.0 3 O14920,O75116 2 +Negative regulation of vascular associated smooth muscle cell migration 0.5196923076923103 0.0568998119400236 0.9546250041220689 1.0 1.0 2 P09493 1 +Fibroblast migration 0.3189843745736775 0.0567997369544136 0.9547047234814616 1.0 1.0 16 Q06481,O95470 2 +Regulation of vesicle size 0.3121921182265909 0.0563655132799734 0.9550506296755764 1.0 1.0 4 Q12768,Q96CW1,P20339 3 +Positive regulation of neurotrophin trk receptor signaling pathway 0.5181538461538554 0.0561718557721738 0.9552049015923156 1.0 1.0 2 Q7L576 1 +Regulation of neurotrophin trk receptor signaling pathway 0.5181538461538554 0.0561718557721738 0.9552049015923156 1.0 1.0 2 Q7L576 1 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.5178461538461656 0.0560279788073654 0.9553195182982206 1.0 1.0 2 Q6P2E9 1 +B cell mediated immunity 0.3168607079846919 0.0542546522387346 0.956732278575809 1.0 1.0 18 Q9UQ84,Q96FV9,P13051 3 +Endocytosis 0.3973816135593471 0.0533052398367715 0.9574887053534512 1.0 1.0 117 O15118,Q08380,P50570,P50897,Q05086,Q9Y6I3,P20645,Q9H223,Q5VW38,Q99816,Q8N6T3,P57105,P0DP25,Q8WTV0,P41440,Q9NVZ3,Q7Z6M1,P51790,P11717,Q9Y5X3,Q9H4M9,P09496,Q14108,O00560,O15260,O75955,P05067,Q06481,O15126,Q9NX40,P61966 31 +Axis elongation 0.4121268082486961 0.0522712278736256 0.95831257879593 1.0 1.0 3 Q13308,Q13263 2 +Pseudouridine synthesis 0.3036964030999824 0.0521467569957987 0.9584117569265742 1.0 1.0 8 Q8IZ73 1 +Organism emergence from protective structure 0.5076923076923179 0.0515907104551535 0.9588548214669111 1.0 1.0 2 Q8IWS0 1 +Catecholamine uptake involved in synaptic transmission 0.5061538461538572 0.0509693249198103 0.959349963932466 1.0 1.0 2 O14656 1 +Dopamine transport 0.5061538461538572 0.0509693249198103 0.959349963932466 1.0 1.0 2 O14656 1 +Catecholamine uptake 0.5061538461538572 0.0509693249198103 0.959349963932466 1.0 1.0 2 O14656 1 +Ketone catabolic process 0.506153846153853 0.0509693249198089 0.959349963932467 1.0 1.0 2 Q6YP21 1 +Regulation of ubiquitin specific protease activity 0.5061538461538516 0.0509693249198083 0.9593499639324674 1.0 1.0 2 P55072 1 +Regulation of cellular amino acid metabolic process 0.5061538461538497 0.0509693249198072 0.9593499639324684 1.0 1.0 2 Q9UPY5 1 +Forebrain radial glial cell differentiation 0.5040000000000122 0.0501210411774491 0.9600259323743504 1.0 1.0 2 Q86U44 1 +Regulation of torc2 signaling 0.503384615384619 0.0498832576252795 0.9602154191720084 1.0 1.0 2 Q9Y4R8 1 +Sterol biosynthetic process 0.3077764087013513 0.0491770209243879 0.9607782237508118 1.0 1.0 22 P04035,P16435,P14324,Q15392,P37268,Q14739,Q16850 7 +Meiotic spindle assembly 0.4065866420437105 0.0489160537882117 0.9609861951044808 1.0 1.0 3 Q12768,O14965 2 +Neuromuscular synaptic transmission 0.5003076923077042 0.0487243761384292 0.9611389495946 1.0 1.0 2 Q8IUD2 1 +Dephosphorylation of rna polymerase ii c terminal domain 0.4053554939981572 0.0482048863866444 0.9615529559434794 1.0 1.0 3 Q9Y5B0,Q9NQG5 2 +Protein localization to axon 0.496615384615398 0.0473983586256921 0.9621957371787382 1.0 1.0 2 O14579 1 +Sertoli cell development 0.4953846153846201 0.0469716456932174 0.9625358260350044 1.0 1.0 2 P51659 1 +Response to arsenite ion 0.4935384615384665 0.0463456146821728 0.9630347830877763 1.0 1.0 2 P55072 1 +Intracellular mrna localization 0.4935384615384645 0.0463456146821723 0.9630347830877768 1.0 1.0 2 Q99729 1 +Negative regulation of cell size 0.4889230769230843 0.0448524632611206 0.964224907503342 1.0 1.0 2 P35241 1 +Positive t cell selection 0.488923076923076 0.0448524632611178 0.9642249075033442 1.0 1.0 2 P40763 1 +T helper cell lineage commitment 0.488923076923076 0.0448524632611178 0.9642249075033442 1.0 1.0 2 P40763 1 +T cell selection 0.488923076923076 0.0448524632611178 0.9642249075033442 1.0 1.0 2 P40763 1 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.488923076923076 0.0448524632611178 0.9642249075033442 1.0 1.0 2 P40763 1 +Negative regulation of gtpase activity 0.3064765002705027 0.0447336554893952 0.9643196073386442 1.0 1.0 10 Q4VCS5,Q9Y624,Q9Y6D6 3 +Medium chain fatty acyl coa metabolic process 0.4883076923076933 0.0446609641368518 0.9643775487385132 1.0 1.0 2 P51659 1 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.2983374384236356 0.0442011557091891 0.9647440608327836 1.0 1.0 4 P04818,P33316,P32321 3 +Dtmp metabolic process 0.2983374384236356 0.0442011557091891 0.9647440608327836 1.0 1.0 4 P04818,P33316,P32321 3 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.2983374384236356 0.0442011557091891 0.9647440608327836 1.0 1.0 4 P04818,P33316,P32321 3 +Phototransduction 0.3979686057248432 0.0441910794829292 0.9647520926500543 1.0 1.0 3 O96017,Q15555 2 +Cell cycle g2 m phase transition 0.2942805083366323 0.0441245588855197 0.9648051166863554 1.0 1.0 53 P53350,O43768,Q6NUQ1,P11802,Q96K76,Q9Y619,P05067,P50570,Q9UN37,O43823,P0DP25,Q9NWV8,Q9Y570,P08183,Q07666 15 +Convergent extension 0.4849230769230778 0.0436387367017158 0.9651923736719208 1.0 1.0 2 Q13308 1 +Negative regulation of dephosphorylation 0.3132480928092489 0.0432566366766812 0.9654969577630949 1.0 1.0 14 Q15257,O43768,O95429 3 +Regulation of dna directed dna polymerase activity 0.2990135635018571 0.043238525329418 0.9655113950197513 1.0 1.0 8 Q9BRX5,P40938,Q8WVB6,P35250,P40937,Q9BRT9,P12004 7 +Abscission 0.2966242419247977 0.0428651228277034 0.9658090511344644 1.0 1.0 4 Q9UN37,Q8N0X7 2 +Positive regulation of extracellular matrix assembly 0.4821538461538566 0.0428405320348509 0.9658286537413844 1.0 1.0 2 O75122 1 +Embryonic body morphogenesis 0.4821538461538566 0.0428405320348509 0.9658286537413844 1.0 1.0 2 O75122 1 +Positive regulation of basement membrane assembly involved in embryonic body morphogenesis 0.4821538461538566 0.0428405320348509 0.9658286537413844 1.0 1.0 2 O75122 1 +Regulation of extracellular matrix assembly 0.4821538461538566 0.0428405320348509 0.9658286537413844 1.0 1.0 2 O75122 1 +Positive regulation of ubiquitin dependent protein catabolic process 0.2711074914927658 0.0425670556676752 0.9660466574438658 1.0 1.0 30 P53350,O75832,P54725,P63244,P04062,Q8IXJ6 6 +Response to interferon gamma 0.2958769990632778 0.0417859676255158 0.9666693214556838 1.0 1.0 25 P19474,Q6ZWJ1,Q16543,P08238,P42224,O60506,Q9UNK0,Q13137,Q08722 9 +Interstrand cross link repair 0.2951823367815477 0.0417681543862537 0.966683521966622 1.0 1.0 4 Q9H1E3 1 +Establishment of planar polarity involved in neural tube closure 0.4753846153846133 0.04102765053578 0.9672738524756844 1.0 1.0 2 Q13308 1 +Negative regulation of necrotic cell death 0.2940270935960491 0.0409072010629412 0.9673698766364284 1.0 1.0 4 Q13546,P12235,P16989 3 +Negative regulation of programmed necrotic cell death 0.2940270935960491 0.0409072010629412 0.9673698766364284 1.0 1.0 4 Q13546,P12235,P16989 3 +Deoxyribonucleotide biosynthetic process 0.3012059114378148 0.0404339295318576 0.9677471805033566 1.0 1.0 9 P27707,P31350 2 +Hair follicle maturation 0.2956575300277144 0.0392927283611475 0.9686570040681566 1.0 1.0 5 P35222,P18074,P21359,Q08J23 4 +Membrane disassembly 0.2874306839186784 0.0389157464249827 0.9689575622471004 1.0 1.0 6 P53350,Q9ULX6,P43034,Q14203,Q99986 5 +Cardiac neural crest cell differentiation involved in heart development 0.465538461538477 0.0387175429849037 0.9691155866165436 1.0 1.0 2 P60953 1 +Outer ear morphogenesis 0.4655384615384655 0.0387175429849012 0.9691155866165456 1.0 1.0 2 O75569 1 +Trachea morphogenesis 0.4655384615384648 0.0387175429849012 0.9691155866165456 1.0 1.0 2 P35222 1 +Trachea development 0.4655384615384648 0.0387175429849012 0.9691155866165456 1.0 1.0 2 P35222 1 +Trachea formation 0.4655384615384648 0.0387175429849012 0.9691155866165456 1.0 1.0 2 P35222 1 +Primitive hemopoiesis 0.3859649122807066 0.0385417489101841 0.9692557453795144 1.0 1.0 3 Q13188,Q13043 2 +Positive regulation of tau protein kinase activity 0.3848716503564562 0.0380776822284762 0.9696257454047048 1.0 1.0 3 P08238 1 +Transepithelial chloride transport 0.4615384615384648 0.0378813973668931 0.9697822451531432 1.0 1.0 2 P55011 1 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.2813085944731377 0.0376699997765844 0.9699507957222966 1.0 1.0 28 P53350,O75832,P54725,P63244,P04062,Q8IXJ6 6 +Amino acid transport 0.3043435026432203 0.0369293895398282 0.9705413062604038 1.0 1.0 22 Q9Y619 1 +L serine biosynthetic process 0.4544615384615548 0.0365353343444673 0.970855504774587 1.0 1.0 2 O43175 1 +Vitamin b6 metabolic process 0.4544615384615432 0.0365353343444651 0.9708555047745888 1.0 1.0 2 O00764 1 +Peripheral nervous system myelin maintenance 0.4535384615384639 0.0363717071191437 0.970985973695038 1.0 1.0 2 P31751 1 +Endocardium development 0.4480000000000068 0.0354445915936179 0.9717252280832878 1.0 1.0 2 Q13043 1 +Peroxisome proliferator activated receptor signaling pathway 0.377962449984616 0.0353273646782127 0.9718187030876436 1.0 1.0 3 Q15648,Q15120 2 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2980617051530172 0.0344573871151993 0.9725124223090847 1.0 1.0 9 P67809 1 +Crd mediated mrna stabilization 0.2980617051530172 0.0344573871151993 0.9725124223090847 1.0 1.0 9 P67809 1 +Cellular anion homeostasis 0.436923076923085 0.0338505965659706 0.9729962888162512 1.0 1.0 2 P55011 1 +Cellular monovalent inorganic anion homeostasis 0.436923076923085 0.0338505965659706 0.9729962888162512 1.0 1.0 2 P55011 1 +Regulation of adherens junction organization 0.4366153846153817 0.0338109011887906 0.9730279430252216 1.0 1.0 2 P35241 1 +Nucleotide excision repair dna gap filling 0.3730378578024059 0.0335509885771525 0.973235205691265 1.0 1.0 3 Q07864,Q15054 2 +Positive regulation of transporter activity 0.3098899912265843 0.0333286992894139 0.97341246774464 1.0 1.0 18 P08183 1 +Forebrain morphogenesis 0.4264615384615421 0.032626296209472 0.9739725996472316 1.0 1.0 2 P21359 1 +Lateral ventricle development 0.4264615384615383 0.0326262962094717 0.973972599647232 1.0 1.0 2 Q00534 1 +Negative regulation of centriole replication 0.4206153846153858 0.032046040853228 0.9744353344433796 1.0 1.0 2 Q96PK6 1 +Protein k6 linked ubiquitination 0.4206153846153836 0.0320460408532277 0.9744353344433798 1.0 1.0 2 Q16763 1 +Connective tissue replacement 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +Regulation of connective tissue replacement 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +Positive regulation of connective tissue replacement 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +Positive regulation of tissue remodeling 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +Negative regulation of biomineralization 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 1.0 2 O75116 1 +Glutamate secretion 0.4123076923076942 0.0313342003653073 0.9750030158439632 1.0 1.0 2 P21359 1 +Glutamate secretion neurotransmission 0.4123076923076942 0.0313342003653073 0.9750030158439632 1.0 1.0 2 P21359 1 +Regulation of vitamin d receptor signaling pathway 0.4119999999999977 0.03131018484193 0.975022168062054 1.0 1.0 2 Q13573 1 +Vitamin d receptor signaling pathway 0.4119999999999977 0.03131018484193 0.975022168062054 1.0 1.0 2 Q13573 1 +Osteoblast proliferation 0.4110769230769205 0.031239092616445 0.9750788637172724 1.0 1.0 2 P06756 1 +Regulation of osteoblast proliferation 0.4110769230769205 0.031239092616445 0.9750788637172724 1.0 1.0 2 P06756 1 +Response to glycoside 0.4092307692307667 0.0311011289801429 0.975188889310456 1.0 1.0 2 P05023 1 +Positive regulation of isotype switching to iga isotypes 0.4089230769230754 0.0310786727116546 0.9752067981630972 1.0 1.0 2 P43246 1 +Negative regulation of innate immune response 0.3095103105762257 0.0307666564283584 0.9754556321398892 1.0 1.0 16 P46108,P01889 2 +Cellular response to antibiotic 0.3641120344721503 0.030693015447555 0.9755143614052612 1.0 1.0 3 P61160,P62829 2 +Negative regulation of neuroblast proliferation 0.3641120344721505 0.030693015447555 0.9755143614052612 1.0 1.0 3 P35221,P21359 2 +Mechanosensory behavior 0.3990769230769375 0.0304358054703573 0.9757194894384263 1.0 1.0 2 Q96SI9 1 +Observational learning 0.3990769230769239 0.0304358054703564 0.9757194894384272 1.0 1.0 2 P21359 1 +Epithelial cell maturation 0.3628808864265979 0.030333325827547 0.975801218627391 1.0 1.0 3 P04818,Q86UL3 2 +Negative regulation of signal transduction by p53 class mediator 0.2870567738625268 0.0301768160512461 0.9759260382203008 1.0 1.0 7 O75832,P14174 2 +Positive regulation of chemokine c c motif ligand 5 production 0.3923076923077 0.0300709480195864 0.9760104703706088 1.0 1.0 2 O00571 1 +Dump metabolic process 0.3904615384615353 0.0299811673392462 0.976082072704962 1.0 1.0 2 P32321 1 +Negative regulation of calcium ion dependent exocytosis 0.389846153846155 0.0299521138542287 0.9761052436260198 1.0 1.0 2 P04899 1 +Plasma membrane phospholipid scrambling 0.3852307692307621 0.02974751534143 0.9762684169094348 1.0 1.0 2 Q7Z3C6 1 +Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process 0.3655384615384663 0.0290989681200922 0.9767856587716032 1.0 1.0 2 P04899 1 +Positive regulation of chromatin binding 0.3649230769230695 0.0290836231714099 0.9767978970894816 1.0 1.0 2 P56545 1 +Regulation of long chain fatty acid import across plasma membrane 0.3603076923076953 0.0289764307314002 0.9768833882512524 1.0 1.0 2 P31751 1 +Regulation of t circle formation 0.3498461538461485 0.028779306211516 0.9770406052941948 1.0 1.0 2 Q15554 1 +Regulation of retrograde protein transport er to cytosol 0.3568818678478108 0.0286927824435761 0.9771096127750554 1.0 1.0 3 Q13438 1 +Positive regulation of synaptic vesicle endocytosis 0.3326153846153789 0.0285623809358237 0.9772136154988752 1.0 1.0 2 O14656 1 +Isopentenyl diphosphate biosynthetic process 0.3116923076922979 0.0284186068205638 0.9773282840974172 1.0 1.0 2 Q15126 1 +Response to dopamine 0.2982664722357531 0.0283372736727265 0.9773931524356014 1.0 1.0 10 Q92542 1 +Positive regulation of receptor catabolic process 0.2833846153846042 0.0283363570628251 0.9773938834909216 1.0 1.0 2 Q96J02 1 +Negative regulation of macrophage migration 0.2735384615384519 0.0283235546274284 0.9774040942581316 1.0 1.0 2 P14174 1 +Negative regulation of macrophage chemotaxis 0.2735384615384519 0.0283235546274284 0.9774040942581316 1.0 1.0 2 P14174 1 +Methylguanosine cap decapping 0.2801248808836311 0.0277177475645929 0.977887268631926 1.0 1.0 6 Q96C86 1 +Sphingomyelin metabolic process 0.2848783492454558 0.0274787896230484 0.9780778568877422 1.0 1.0 5 O15269,Q9NXE4,Q9P0L0,O15270 4 +Regulation of fibroblast migration 0.2922285653591783 0.0238941735227411 0.9809370218128636 1.0 1.0 9 Q06481 1 +Regulation of release of cytochrome c from mitochondria 0.2989869256339434 0.0237995974287525 0.981012461164803 1.0 1.0 11 O60313,Q96A26 2 +Positive regulation of synaptic vesicle recycling 0.3327177593105622 0.0237303705325076 0.9810676806410212 1.0 1.0 3 Q9Y263,O14656 2 +Negative regulation of lipid biosynthetic process 0.276956253850897 0.0231602011202396 0.981522484990022 1.0 1.0 6 P05023,Q8NF37,O60678,O75477,P38398 5 +Protein modification by small protein removal 0.2768913724424071 0.0225794693465668 0.981985720740904 1.0 1.0 45 P19474,Q96RU2,Q96FW1,Q9H8M7,O75486,P51784,Q15018,Q92905,Q9UBW8,O00303,Q96K76,Q9NWV8,Q9BT78,Q9Y6J9,P06493 15 +Dephosphorylation 0.3567474226028816 0.022253166659319 0.9822460072119918 1.0 1.0 94 O43768,Q9C0I1,Q05D32,Q9NPH0,P30154,Q96DE0,P0DP25,P29218,Q5TFE4,Q08623,Q969T7,P11117,Q9NQ88,Q86XL3,P78318,P04062,Q5MIZ7,Q10713,O95429,P63151 20 +Regulation of metallopeptidase activity 0.3120960295475587 0.0211272411314668 0.9831441544615996 1.0 1.0 3 P40763,Q96HY6 2 +Single strand break repair 0.3052691040577077 0.0205126480047592 0.983634422551068 1.0 1.0 3 P18887 1 +Small gtpase mediated signal transduction 0.3703242488011967 0.0204658802896564 0.9836717299570572 1.0 1.0 103 P80303,P46108,P50570,P16949,Q9Y624,P61225,P52565,Q6UWU4,P31150,Q8N6T3,Q92538,Q4VCS5,P57105,Q02818,Q04721,P41440,Q9H0H5,Q15555,Q9NUQ9,Q7Z569,Q9Y2I1,P06400,O00560,P09601,P46109,O14786,O94813,Q9Y6D6,Q96EY1,Q9Y6N7,O75955,P11233,Q15392,P84095,Q86VI3 35 +Regulation of adenylate cyclase activity 0.2558497536945716 0.020387299509958 0.9837344152689896 1.0 1.0 4 P04899,P21359,P08754 3 +Positive regulation of actin filament depolymerization 0.3000923361034213 0.0201132351150576 0.9839530421865328 1.0 1.0 3 P60981,Q9Y281 2 +Regulation of humoral immune response 0.296398891966764 0.0198598898814577 0.9841551420667234 1.0 1.0 3 Q07021,P35232 2 +Regulation of complement activation 0.296398891966764 0.0198598898814577 0.9841551420667234 1.0 1.0 3 Q07021,P35232 2 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.2923976608187191 0.0196126141539932 0.9843524011295448 1.0 1.0 3 Q9UN37,Q8WUM4 2 +Peptidyl serine dephosphorylation 0.2762055466909455 0.0192156655642448 0.9846690605971612 1.0 1.0 5 P63151 1 +Regulation of macrophage migration 0.2736226531240435 0.018764924980748 0.98502863470393 1.0 1.0 3 P28482,P14174 2 +Regulation of macrophage chemotaxis 0.2736226531240435 0.018764924980748 0.98502863470393 1.0 1.0 3 P28482,P14174 2 +Regulation of synaptic transmission gabaergic 0.2621051833039826 0.0184405843989201 0.9852873762712304 1.0 1.0 3 P21359 1 +Histone h2a monoubiquitination 0.2603878116343548 0.0184018708793109 0.9853182599503154 1.0 1.0 3 Q16531,P63208 2 +Protein k29 linked ubiquitination 0.2536164973838162 0.0182695550892191 0.9854238149311054 1.0 1.0 3 Q96J02,Q16763 2 +Negative regulation of telomerase activity 0.2484605911329955 0.0179155480618312 0.9857062254452282 1.0 1.0 4 Q96BK5,P27544,P04637 3 +Regulation of bone resorption 0.248460591132994 0.0179155480618309 0.9857062254452283 1.0 1.0 4 P02786,P41240,P21359 3 +Regulation of bone remodeling 0.248460591132994 0.0179155480618309 0.9857062254452283 1.0 1.0 4 P02786,P41240,P21359 3 +Cellular glucose homeostasis 0.2858065462336616 0.0172068036270105 0.9862716344841412 1.0 1.0 26 Q6ZWJ1,Q15907,Q9H1E3,Q8N183,P30626,P63244,P52789,Q15043,P62995 9 +Regulation of rna polymerase ii transcription preinitiation complex assembly 0.2459975369458046 0.0171788388635734 0.986293943839644 1.0 1.0 4 P62333,P09429,P04637 3 +Macrophage chemotaxis 0.2737911918694141 0.0171035698438495 0.9863539910061704 1.0 1.0 5 P17931,P28482,P14174,Q9BW27 4 +Macrophage migration 0.2737911918694141 0.0171035698438495 0.9863539910061704 1.0 1.0 5 P17931,P28482,P14174,Q9BW27 4 +Positive regulation of cell cycle phase transition 0.27073830529193 0.0168654166321322 0.9865439823707892 1.0 1.0 42 P31350,Q6ZWJ1,P11802,P05067,P06400,P30260,P14635,Q96FV9,P04083,Q9UJX4,Q13042,Q96HY6,Q9NYL9,P06493 14 +Response to chemokine 0.2717190388170112 0.0160177885823891 0.9872202002788236 1.0 1.0 6 O95747,Q9Y6N7,P55011,Q96T37,O94813 5 +Skeletal muscle organ development 0.2926624101839951 0.0156996088987471 0.9874740390128768 1.0 1.0 24 O75955,P06400,Q9BYT8,P51114,P41440,Q16539,Q9Y281 7 +Positive regulation of protein exit from endoplasmic reticulum 0.2396599161160739 0.0154678467948198 0.9876589359642522 1.0 1.0 4 Q9NR31 1 +Positive regulation of mitotic cell cycle 0.2653392848479896 0.0153794532944659 0.9877294553850416 1.0 1.0 39 P31350,P11802,Q96DY7,P05067,P06400,Q16513,P30260,P14635,P35241,P04083,Q9UJX4,P08243,Q13042,Q9NYL9,P06493 15 +Dna strand elongation involved in dna replication 0.299475146650202 0.0148383922569715 0.9881611103562332 1.0 1.0 13 P49916,P40938,P33993,P09884,P25205,P18858,P12004,P33991,P51530,Q07864,Q15054,P49005 12 +Response to tumor cell 0.2689541965038976 0.0131094710230578 0.9895404550644152 1.0 1.0 5 P04439 1 +Cellular response to starvation 0.2592218381039872 0.0128581973523178 0.9897409255479432 1.0 1.0 31 P04062 1 +Positive regulation of viral process 0.2756149577654609 0.0119747547784476 0.9904457563814876 1.0 1.0 28 P19474,Q9H9H4,Q99816,P07237,P54725,O43447,P52292,Q9UN37,O95793,P27105 10 +Positive regulation of mitochondrial fission 0.2845976150975392 0.0110959789211133 0.9911468713995252 1.0 1.0 9 Q9NQG6,Q8NE86,Q9Y3D6 3 +Regulation of cation transmembrane transport 0.2764283878850922 0.0108918263142432 0.9913097517686736 1.0 1.0 46 P05067,P27105,Q8TAD4,P21796 4 +Cellular response to external stimulus 0.2780867124029064 0.0107056466116773 0.99145829301752 1.0 1.0 47 Q9H773,P09601,P04062 3 +Ubiquitin dependent erad pathway 0.2591300917301973 0.0096376288947527 0.99231040374225 1.0 1.0 36 Q9UBU6,P46379 2 +Signal transduction in absence of ligand 0.2999703721605267 0.0089650883038721 0.9928469902741476 1.0 1.0 15 P49327,P42575,P30154,P21359,P30153,O95817 6 +Tube formation 0.2960541727077077 0.0088844562841943 0.9929113227555952 1.0 1.0 22 P07737,O95747,Q9Y366,O60313,Q13308,O15078,P11233,P63167,Q13043 9 +Negative regulation of phosphatase activity 0.2831427776295226 0.0087859910851742 0.992989883551304 1.0 1.0 9 P04899,O95429,O14920,Q15257,P49841 5 +Epithelial tube formation 0.2993328296587531 0.0083351362157899 0.9933496005068468 1.0 1.0 20 P07737,O95747,Q9Y366,O60313,Q13308,O15078,P11233,P63167,Q13043 9 +Nucleotide phosphorylation 0.2536632970921018 0.0080156488936093 0.993604505988796 1.0 1.0 33 P05067,Q9BRR6,P52789,Q9NQ88,P27144 5 +Protein demethylation 0.2653783081243124 0.0080095006845866 0.9936094113923826 1.0 1.0 6 Q9Y570 1 +Negative regulation of dna binding transcription factor activity 0.2834458437374235 0.0078032901359008 0.9937739384626988 1.0 1.0 26 P19474,P30626,P09601 3 +Response to axon injury 0.2957730341073776 0.0071907323795692 0.9942626750964773 1.0 1.0 13 P30536,Q96G23 2 +Positive regulation of cytoplasmic translation 0.2924405017782808 0.0056544036743997 0.9954884626483522 1.0 1.0 12 O60506,P67809,P16989 3 +Regulation of transporter activity 0.2633482276689236 0.0046935342644768 0.9962551152242888 1.0 1.0 39 P05067,P08183,P27105 3 +Regulation of ire1 mediated unfolded protein response 0.2558872378355603 0.0038175591423306 0.9969540358989082 1.0 1.0 5 Q92905 1 +Dna damage response signal transduction by p53 class mediator 0.2986393492833116 0.0036722887497255 0.9970699440894302 1.0 1.0 16 O75844,O75832,P14174,P42575 4 +Circulatory system process 0.318160745972244 0.0033002167774741 0.9973668127658144 1.0 1.0 72 Q6P179,P42892,Q9HB40,O75844,P42785,P10253,P33527,P0DP25,Q9NZ08,P09601,Q9UIQ6,P08183 12 +Neural tube formation 0.2988248374654801 0.0028754643711494 0.99770571453476 1.0 1.0 17 Q9Y366,P07737,O60313,P11233,Q13043 5 +Regulation of establishment of protein localization to mitochondrion 0.2966620842295902 0.0015360738180172 0.998774390898326 1.0 1.0 15 P55786,O95429 2 +Keratinocyte differentiation 0.2980469405241004 0.0009576458925824 0.9992359092443815 1.0 1.0 17 Q13510 1 +Pore complex assembly 0.2922172422570822 0.0001378868754673 0.999889982191276 1.0 1.0 13 Q9BTX1 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..62833507f19e508f690015a6b5325572e43553ba --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B 1 b cell differentiation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in bone marrow", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chorionic trophoblast cell differentiation", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Dipeptide transmembrane transport", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fate commitment", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane depolarization", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron fate specification", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide import across plasma membrane", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation in bone marrow", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylase activity", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 17 cell differentiation", "Positive regulation of t helper 17 type immune response", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine biosynthetic process", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinolinate metabolic process", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart morphogenesis", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non membrane spanning protein tyrosine kinase activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of ovarian follicle development", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of somitogenesis", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 17 cell differentiation", "Regulation of t helper 17 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C18orf32", "C19orf70", "C1QBP", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "C6orf89", "C9orf64", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC94", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG2", "COG3", "COG4", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM126A", "FAM162A", "FAM207A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM161A", "TMEM165", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRAP73", "WRN", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF131", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AASS", "ABCB1", "ABCB8", "ABCC1", "ABHD10", "ABHD12", "ABRAXAS2", "ACBD5", "ACOX1", "ACP2", "ACP6", "ACSL6", "ACTR2", "ADD1", "ADPGK", "AHCTF1", "AIFM1", "AIP", "AK4", "AKAP8", "AKAP8L", "AKT2", "ALDH2", "ALDH3A2", "AMOT", "ANAPC1", "ANAPC5", "ANAPC7", "ANKLE2", "ANP32B", "ANXA1", "AP1B1", "AP1M1", "AP1S1", "AP2M1", "AP3B1", "AP3S1", "APLP2", "APOL2", "APP", "APRT", "ARF4", "ARFGAP1", "ARFGEF1", "ARHGDIA", "ARL1", "ARL6", "ASAH1", "ASNA1", "ASNS", "ASNSD1", "ATG3", "ATG4B", "ATG9A", "ATP13A1", "ATP1A1", "ATP5F1", "ATP5L", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "AUP1", "AURKA", "B3GAT3", "B4GAT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BCCIP", "BCL2L13", "BICD2", "BRAP", "BRCA1", "BRD1", "BRD8", "C12orf57", "C12orf73", "C1QBP", "C6orf89", "CAB39", "CADM1", "CALCOCO2", "CALM3", "CAMLG", "CANT1", "CAPNS1", "CARM1", "CASP2", "CCDC134", "CCDC22", "CCDC47", "CCNB1", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDK1", "CDK4", "CDK6", "CDKN2A", "CELF2", "CEP290", "CERS1", "CERS2", "CFDP1", "CFL2", "CHAC2", "CHCHD3", "CHD8", "CHEK2", "CHKA", "CHMP2B", "CHST14", "CHTF18", "CIRBP", "CISD1", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLN5", "CLTA", "CNNM3", "CNNM4", "CNOT9", "COA3", "COMT", "COPE", "COPS3", "COPS4", "COPS5", "COPS7A", "COPS8", "COX2", "COX7A2", "CPNE1", "CPOX", "CPSF2", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CSGALNACT2", "CSK", "CSTB", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTPS1", 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0000000000000000000000000000000000000000..55628c2f36c0e4b560fc7023434da15498d89713 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56dc470342fb9cd095a454ec848f7123dc606092e954b2963fd229e7c5abd522 +size 93785 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6ede9bcb32ae01d796eb001435ee1560c6a512c8 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,16 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosomal lumen 23 36 4.507921165267893 6.546589008671333e-06 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 4.925391275506813e-22 9.304525347895863e-10 6.132250230249374e-14 3.867488965514064e-22 2.899939269601499e-17 +Vacuolar lumen 28 63 3.509017612367318 0.000449765120116 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 1.9938705143762078e-21 6.287420146239293e-08 2.338989253663816e-13 7.399322797138654e-22 2.8387988539414845e-16 +Azurophil granule lumen 15 40 3.0665632080199203 0.0021653502125027 12.118932038834952 41.25728155339806 -0.033426136567579 0.3776020138210581 4.31782609196223 3.0753988435553 1.7699755963815147 0.3570217435028845 1.8652012219655027e-08 0.0366902203239334 0.0003509404267833 2.84269602641998e-09 3.694948134523572e-08 +Tertiary granule 11 42 2.9314221094171025 0.0033741396774185 10.41504854368932 41.036407766990294 -0.0889487004392956 0.5196752089107607 4.251221040765739 3.0949590565759384 1.1107953602779526 0.3305399634314611 0.0016109914096904 0.0720814043883259 0.0121831039178989 2.217529471549688e-06 0.0016866105096048 +Azurophil granule 24 67 2.8330823941233905 0.0046101501353081 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 1.7975142168250225e-15 0.0176779282664691 0.0001223594295393 2.693910886407043e-17 8.289069328892468e-13 +Endoplasmic reticulum golgi intermediate compartment membrane 15 29 2.5135445180754803 0.0119524691554795 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 6.654825632767626e-05 0.0022960708364777 0.0161789595718159 6.375644196764208e-06 1.731244358485392e-06 +Azurophil granule membrane 9 23 2.484026884474228 0.0129906000184372 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 1.3624477940547097e-07 0.1991580424676108 0.0733374275738533 1.1854087112688965e-07 5.9679114156954766e-05 +Golgi lumen 1 5 2.418665134890497 0.0155775731583533 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.1192008340234222 1.0 1.0 0.1834336275650726 0.4689660168937119 +Trans golgi network membrane 12 31 2.370279264050521 0.0177746539919343 7.097087378640777 25.808252427184467 0.4300178223009387 0.4839581535123586 3.4857952056404495 4.861642003007495 1.0577526504941306 0.3235584371830635 0.0413592215141415 1.0 0.4960773916621825 0.007106566949162 0.0020278340379407 +Endocytic vesicle membrane 15 38 2.166084848649773 0.030304703780001 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.3523072033174336 1.0 0.3002915006964563 0.0017538115232115 0.0003861350109005 +Pore complex 2 8 2.101110092359905 0.0356313031720756 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0391020467975167 0.0029386578360865 0.0115435449528709 0.0635022977163126 0.0475092322455766 +Tertiary granule lumen 4 14 2.032279923028901 0.0421253257879581 5.080097087378641 15.28640776699029 -0.3079983292417204 0.4707564584893597 2.953670086665961 1.2697028582661334 0.9645881412270784 0.2886719366464021 0.0212502057537459 0.0102371045657047 0.0035907130786718 0.0009795417899813 0.0185489800864176 +Proteasome core complex beta subunit complex 4 7 2.016316727483837 0.0437668668574251 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0004925675778475 0.0424464003246627 0.0032139762811053 0.0010839430889874 2.9438380117440665e-05 +Proteasome core complex 6 15 2.016039743396961 0.0437958200760055 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 0.0002299143945716 0.0786913117950012 0.0005470061355849 4.060119731401367e-05 8.168923487379343e-06 +Endoplasmic reticulum golgi intermediate compartment 19 53 1.9791880208704404 0.0477948411330024 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 8.45679766511642e-05 0.0012207780133923 0.0025963332517603 2.5382317150750383e-05 4.633700550365833e-06 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5dc9de8e1f9d2e19eb9afa7301a18bd64bb5ad5a --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 907, + "title": "Average number of proteins per term", + "value": 28.960308710033075 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3d717154a71ffa2f39fc005bf8b249baadfd469c --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..51929da70bad613554f55c4446008a848177ad3d --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,254 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosomal lumen 0.8714527857551992 4.507921165267893 6.546589008671333e-06 0.0059201819168441 0.0059377562308658 36 P06280,Q9UM22,P04066,P50897,Q8IV08,P10253,P07602,P15586,Q9UMR5,P16278,P06865,Q13510,P10619,Q8NHP8,O14773,P61916,P17900,Q14108,P04062,P54802,O00462,O00584,P13473 23 +Vacuolar lumen 0.7753591285999972 3.509017612367318 0.000449765120116 0.3350402253276661 0.2039684819726402 63 P06280,Q9UM22,P04066,P50897,Q8IV08,P10253,P07602,P15586,Q9UMR5,P16278,P06865,Q13510,P10619,Q8NHP8,O14773,P02792,P61916,Q99536,P17900,P11117,Q14108,O00560,P04062,P54802,Q9BTY2,O00462,O00584,P13473 28 +Azurophil granule lumen 0.6614819899052137 3.0665632080199203 0.0021653502125027 0.8599984887157051 0.6546575475799977 40 P06280,P15586,Q92820,P61916,P16278,P04066,Q99536,P17900,P10619,O43681,O00560,P02792,O00754,O00584,Q9BTY2 15 +Tertiary granule 0.6470125392363207 2.9314221094171025 0.0033741396774185 0.953370381327736 0.765086171854647 42 O75874,P04080,Q13510,Q15833,P42785,P09960,P10253,Q92820,Q93050,P27105,P13473 11 +Azurophil granule 0.6855185618505839 2.8330823941233905 0.0046101501353081 0.9848699788575326 0.8362812345449057 67 P06280,P04066,P10253,P07602,P27105,P15586,P16278,P06865,P10619,P42785,Q92542,P02792,Q9NQX7,P61916,Q99536,P17900,O00560,Q92820,O15260,Q15833,Q9BTY2,O00462,O00584,P13473 24 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6263206926570432 2.5135445180754803 0.0119524691554795 0.9999816558189736 0.9274530526830472 29 Q9H0U4,Q9Y282,Q8N511,Q03518,Q96RQ1,P24390,O15498,O15260,Q9Y6N7,P53634,Q15904,O95070,Q9Y3B3,Q969X5,Q13190 15 +Azurophil granule membrane 0.7229339679109094 2.484026884474228 0.0129906000184372 0.9999929301707768 0.9274530526830472 23 O00462,O15260,P42785,P10253,Q92542,Q9NQX7,P07602,P27105,P13473 9 +Golgi lumen 0.934011190887038 2.418665134890497 0.0155775731583533 0.999999345936818 0.9274530526830472 5 O00461 1 +Trans golgi network membrane 0.5689896316493028 2.3702792640505215 0.0177746539919343 0.9999999138012338 0.9274530526830472 31 P11717,Q10567,O60499,P05067,O15127,Q8N2H4,P20645,Q9HC07,O15126,Q9BXS5,P61966,Q7Z6M1 12 +Endocytic vesicle membrane 0.5366964106181698 2.1660848486497732 0.030304703780001 0.9999999999992444 0.9274530526830472 38 P11717,Q15907,P04439,P10321,Q03518,O43493,Q9Y487,P01889,Q14108,Q06481,P20645,Q8WTV0,P11279,Q93050,P13473 15 +Pore complex 0.804451264137349 2.101110092359905 0.0356313031720756 0.9999999999999948 0.9274530526830472 8 P45880,P21796 2 +Tertiary granule lumen 0.7441799907291924 2.032279923028901 0.0421253257879581 1.0 0.9274530526830472 14 O75874,P04080,P09960,Q13510 4 +Proteasome core complex beta subunit complex 0.7903831227232498 2.016316727483837 0.0437668668574251 1.0 0.9274530526830472 7 P49721,P20618,P28070,P28072 4 +Proteasome core complex 0.7317839052413482 2.016039743396961 0.0437958200760055 1.0 0.9274530526830472 15 P49721,P28070,P28072,P60900,Q92530,P20618 6 +Dendritic shaft 0.8647568690996996 1.9907498240037436 0.0465083981363323 1.0 0.9274530526830472 4 Q9UQB8 1 +Endoplasmic reticulum golgi intermediate compartment 0.5435443623978954 1.9791880208704404 0.0477948411330024 1.0 0.9274530526830472 53 P80303,P24390,P53634,Q15904,P07237,Q9Y282,Q8N511,Q03518,Q92538,O95070,Q02818,Q96RQ1,Q9Y3B3,Q13190,Q9H0U4,O15498,O15260,Q9Y6N7,Q969X5 19 +Glial cell projection 0.8206269255106056 1.9591781919793456 0.0500919221603137 1.0 0.9274530526830472 5 P05067 1 +Haus complex 0.8197333314131531 1.9554688649474017 0.0505277548014364 1.0 0.9274530526830472 5 Q96CS2,O94927,Q9H6D7 3 +Secondary lysosome 0.8516773267570011 1.937320256737021 0.0527062075936306 1.0 0.9274530526830472 4 P02792,P13473 2 +Autolysosome 0.8516773267570011 1.937320256737021 0.0527062075936306 1.0 0.9274530526830472 4 P02792,P13473 2 +Copi coated vesicle membrane 0.7243620531894828 1.936452869635351 0.0528122595698334 1.0 0.9274530526830472 14 P24390,O43731 2 +Golgi stack 0.4876882164642619 1.875174244905678 0.0607687561297556 1.0 0.9274530526830472 32 Q9BXS4,Q8N6G5,O00461,Q8NBN3 4 +Exocytic vesicle 0.4969946340830239 1.8496787401497592 0.0643598664543085 1.0 0.9274530526830472 38 P51790,Q15907,O60499,P05067,O43760,Q7L0J3,P50897,O15126,P0DP25,Q92542,P11279,Q9BT78 12 +Phagocytic vesicle membrane 0.6227497716108289 1.826987878036592 0.067701592013343 1.0 0.9274530526830472 22 Q15907,P04439,P10321,Q03518,Q9Y487,P01889,Q06481,P11279,Q93050,P13473 10 +Golgi associated vesicle 0.512145182799052 1.8154449501626508 0.0694555585931309 1.0 0.9274530526830472 30 Q8N511,P24390,O43731 3 +Phagocytic cup 0.8214285714285688 1.812831781939172 0.0698577704417939 1.0 0.9274530526830472 4 P50570,P63244,P04083 3 +Copi coated vesicle 0.6892508804581352 1.8046767119558744 0.0711252860832003 1.0 0.9274530526830472 15 P24390,O43731 2 +Membrane microdomain 0.5385249433710421 1.801789593461775 0.0715785156425725 1.0 0.9274530526830472 62 O15118,P21796,O75955,P05067,P30154,P46108,P50897,O00560,O14773,P09601,P41440,Q8WTV0,P27105,P13473 14 +Golgi medial cisterna 0.8060927643548172 1.7492562414904935 0.0802467362537053 1.0 0.9354151513007812 4 Q9BXS4 1 +Phagocytic vesicle 0.4825114801630711 1.6988647220532969 0.0893446753574103 1.0 0.9354151513007812 40 Q6ZWJ1,Q15907,P04439,P10321,Q03518,Q9Y487,P01889,P50570,Q06481,Q9UNK0,P11279,Q93050,P13473 13 +Golgi cisterna 0.576697136751143 1.691957871842951 0.0906540063884151 1.0 0.9354151513007812 24 Q9BXS4,Q8N6G5,O00461,Q8NBN3 4 +Pole plasm 0.7531454247070667 1.675550901176844 0.0938261928861936 1.0 0.9354151513007812 5 Q9HCE1,Q9Y2W6 2 +Proteasome complex 0.4914776774458441 1.674205079722438 0.0940903015158598 1.0 0.9354151513007812 46 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P54725,P54727,P28072,Q05086,P61289,P60900,P49721,P20618,Q99436,Q5VYK3 18 +Platelet alpha granule lumen 0.681943408058222 1.6598486695697958 0.0969448999143036 1.0 0.9354151513007812 12 Q9NTK5,P05067,Q8NBX0 3 +Endosome lumen 0.9522811106819312 1.608123219743525 0.1078081947049915 1.0 0.9446464003991668 3 Q9UIQ6 1 +Vacuolar proton transporting v type atpase v0 domain 0.7717240541703201 1.605787824610607 0.1083205366991542 1.0 0.9446464003991668 4 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.7717240541703201 1.605787824610607 0.1083205366991542 1.0 0.9446464003991668 4 Q9Y487 1 +Nuclear envelope lumen 0.7357950782051451 1.601583192970947 0.10924780983551 1.0 0.9446464003991668 5 Q9HB71,P05067 2 +Dendrite terminus 0.7673736938811333 1.5875413956896167 0.1123900792026799 1.0 0.9446464003991668 4 P08238,Q9Y366 2 +Blood microparticle 0.6021733836779639 1.5825493790762384 0.1135242090887642 1.0 0.9446464003991668 20 P04062,O00560,Q08380 3 +N terminal protein acetyltransferase complex 0.723586243344076 1.5493190386515665 0.1213050452599333 1.0 0.945016060580116 5 Q14CX7,Q5VZE5,Q9BXJ9 3 +Endoplasmic reticulum lumen 0.5109483368037894 1.5374377174907703 0.1241861559722095 1.0 0.945016060580116 65 O14657,O43493,O14975,O75718,P07237,Q6P179,Q9UBS4,Q02818,O95881,Q9NZ08,Q9NWM8,Q9Y680,P05067,O43681,O15460,Q06481,O43852,Q9BTY2,O00584,Q32P28 20 +Golgi associated vesicle membrane 0.5938701828539314 1.5350261400511616 0.1247774072252139 1.0 0.945016060580116 20 P24390,O43731 2 +Ficolin 1 rich granule membrane 0.6022920458733153 1.5297783497068356 0.1260716023486152 1.0 0.945016060580116 19 P42785,P10253,Q93050,P13473 4 +Cis golgi network 0.5966568822281142 1.4981929711966149 0.1340831212888655 1.0 0.9611123530856494 19 P24390,O43731 2 +Magnesium dependent protein serine threonine phosphatase complex 0.6562687290739512 1.4846106770941494 0.1376469854600528 1.0 0.9611123530856494 10 Q8TF05,Q6IN85,P63151,Q15257,P30154,P30153,Q5MIZ7 7 +Copii coated er to golgi transport vesicle 0.4464468992343766 1.4841998670353964 0.1377559050729155 1.0 0.9611123530856494 35 P04439,Q9Y282,P10321,Q96RQ1,P05067,Q15437,P01889,P53634,O15027,O95070,Q9Y3B3,Q969X5,O95486,Q9NR31,Q13190 15 +Recycling endosome 0.4587214060683544 1.4704624664832495 0.1414365439237581 1.0 0.9645334236003658 42 P51790,Q15907,P04439,P10321,P05067,Q9H4M9,P01889,O15127,O15126,O14773,Q9UNK0,Q9H223,P61225 13 +Protein phosphatase type 2a complex 0.6637146254504673 1.461934265187168 0.1437592241268268 1.0 0.9662304490475184 7 Q15257,P30154,P63151 3 +Platelet alpha granule 0.603143340978756 1.4414131317457817 0.1494680025721431 1.0 0.9789121305086418 17 Q9NTK5,Q8NBM8,P05067,Q8NBX0 4 +Postsynaptic density intracellular component 0.7256461507610591 1.411789061423682 0.1580120802227522 1.0 0.983218277839615 4 Q9UQB8 1 +Er ubiquitin ligase complex 0.6550349007701108 1.4095587644404877 0.1586700101552804 1.0 0.983218277839615 6 Q9UBU6,Q9UBV2 2 +Intrinsic component of golgi membrane 0.6188695947837485 1.381427952291347 0.1671474162700654 1.0 0.9977580455430664 13 Q9Y282,Q8N2H4,O95070,Q969X5,Q8N6G5 5 +Intrinsic component of vacuolar membrane 0.8922782325411668 1.3791492093023516 0.1678487541790354 1.0 0.9977580455430664 3 P13473 1 +Neuromuscular junction 0.5968072244279009 1.332089561992507 0.1828307598854037 1.0 1.0 15 P05067,P10644,O43760,Q15375,Q7L0J3,P57105,Q15650 7 +Respirasome 0.4430474657923391 1.32417298315623 0.1854456012996364 1.0 1.0 43 P14406,O75380,P00403,O43676,Q6DKK2,Q9UDW1,O95168,O95182,O75306 9 +Ciliary base 0.6685025290287626 1.3118484063278568 0.1895712885081035 1.0 1.0 5 P10644,Q9Y366,A0AVF1 3 +Myofilament 0.6266173752310557 1.2835783055821606 0.1992895445529077 1.0 1.0 6 P67936,P09493,P06753,Q13049,Q9NYL9 5 +Golgi cisterna membrane 0.5672333727676869 1.2473368791384865 0.2122740003911458 1.0 1.0 17 Q8N6G5,O00461,Q8NBN3 3 +Mhc class i protein complex 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 1.0 3 P01889,P10321 2 +Mhc protein complex 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 1.0 3 P01889,P10321 2 +Synaptic vesicle membrane 0.5753926461502048 1.2208454789865189 0.2221445306628711 1.0 1.0 15 Q15907,O60499,O43760,Q7L0J3,O15126,P0DP25 6 +Coated vesicle membrane 0.4577462212913872 1.211236775296307 0.2258046721332376 1.0 1.0 58 O43493,P24390,Q15437,O43731,Q9Y6I3,P20645,Q8N511,Q9NVZ3,P11717,P09496,Q14108,O15027,Q9Y3B3,Q13190,P04439,P10321,P01889,O95486,Q9NR31,P61966 20 +Cul2 ring ubiquitin ligase complex 0.642380730557258 1.1987476721827297 0.2306260751522473 1.0 1.0 5 Q8N668,Q15369,Q15370 3 +Proton transporting v type atpase complex 0.5843949448387509 1.1850159081117866 0.2360111571917935 1.0 1.0 12 Q9Y487,Q8N511,Q15904 3 +Centriolar satellite 0.4426543940598159 1.18315382633484 0.2367481886642868 1.0 1.0 29 Q86UY6,Q7Z4H7,Q03518,O75955,P54725,Q96R06,P11413,P41440,Q9UPT5,Q86VS8,Q00013 11 +Ciliary tip 0.5883134719432622 1.1825535835048837 0.2369861174715222 1.0 1.0 11 Q9Y366,Q9Y496,A0AVF1,Q15555,Q96FJ2,Q6PHR2,Q96EX3 7 +Endopeptidase complex 0.4464578402919184 1.1794304203729709 0.238226827806073 1.0 1.0 54 P28070,Q05086,P49721,Q99436,P25787,P28074,O00231,P54725,P61289,P42575,Q9UL46,P28072,P60900,Q92530,O75832,P54727,P04632,P20618,Q5VYK3 19 +Cytoplasmic ubiquitin ligase complex 0.5945760277239667 1.176604928490954 0.2393532297392475 1.0 1.0 9 Q9UBU6,Q9UBV2 2 +Caveola 0.5655273357687319 1.1695096354558985 0.2421983614276934 1.0 1.0 15 P09601,P41440,Q8WTV0 3 +Er membrane insertion complex 0.834572222488111 1.159513237081243 0.2462470440629072 1.0 1.0 3 P46379 1 +Epsilon dna polymerase complex 0.8309657643112254 1.1458678032842382 0.2518498550009949 1.0 1.0 3 Q9NRG0 1 +Mitotic spindle microtubule 0.5906390576332058 1.1327973975672243 0.2572993445899389 1.0 1.0 7 Q96CS2,O94927,Q9H6D7 3 +Striated muscle thin filament 0.6264243917462411 1.1297079225937188 0.2585993177694665 1.0 1.0 5 P06753,Q9NYL9,P67936,P09493 4 +Autophagosome 0.3976250297125752 1.1057990001775664 0.2688135278748647 1.0 1.0 33 P19474,O75787,P11279,Q9NRR5,Q9UQN3,P60520,Q13137,P02792,Q9P253,Q6PHR2,Q13772,P13473 12 +Specific granule 0.3992410279570343 1.1029842418658344 0.2700340084487487 1.0 1.0 34 Q92820,O14975,P30519,Q08722,Q15833,O15126,Q9BXS5,P27105,P61225 9 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6191477127844139 1.0982679848555177 0.2720874873940153 1.0 1.0 5 O75964 1 +Plasma membrane raft 0.5226177833478255 1.079090909863072 0.280547203117838 1.0 1.0 19 O75955,P09601,P41440,Q8WTV0 4 +Cornified envelope 0.6146987633712164 1.0790659005620662 0.2805583510200855 1.0 1.0 5 P04083 1 +Transport vesicle membrane 0.4149899781946262 1.0741084982383835 0.282774056136311 1.0 1.0 44 O60499,Q15907,P04439,P10321,O43760,Q15437,P01889,Q7L0J3,P09496,O15027,Q9Y3B3,O95486,P0DP25,O15126,Q9NR31,P61966,Q13190 17 +Nucleotide activated protein kinase complex 0.6398198261510673 1.04963622797699 0.2938853940762498 1.0 1.0 4 P54619,P10644 2 +Snare complex 0.5437275322273587 1.0294460498027298 0.3032701192343112 1.0 1.0 14 O60499,Q9P2W9,O15498,Q13190 4 +Ubiquitin conjugating enzyme complex 0.6347995398954049 1.0286285143642402 0.3036542734351641 1.0 1.0 4 Q9UNE7,P61088 2 +Specific granule membrane 0.526644153159944 1.027048314135382 0.3043977145742587 1.0 1.0 17 O14975,P30519,O15126,Q9BXS5,P27105,P61225 6 +Lumenal side of membrane 0.5624092578931286 1.0267429441630995 0.3045415220450154 1.0 1.0 9 P10619,P10321 2 +Mcrd mediated mrna stability complex 0.6010475207874317 1.0202724449783511 0.3075992678797841 1.0 1.0 5 O60506,P11940 2 +Platelet dense granule 0.7959850929629921 1.0144102434974869 0.3103870384690741 1.0 1.0 3 P13473 1 +Secretory granule membrane 0.4669233851459716 0.9968902515769764 0.3188177840035449 1.0 1.0 78 O00462,P10321,O15260,P30519,Q8TAD4,P01889,P42785,P10253,Q06481,Q92542,Q9NQX7,P07602,Q93050,P27105,P13473 15 +Postsynaptic density membrane 0.6268993336204427 0.9956545864466776 0.3194180026211759 1.0 1.0 4 P57105 1 +Integral component of synaptic vesicle membrane 0.5616167317713208 0.9946480530381951 0.3199074676464963 1.0 1.0 6 O60499,Q7L0J3 2 +Recycling endosome membrane 0.4585504520136138 0.9927121854560896 0.3208502348870818 1.0 1.0 25 Q15907,P04439,P10321,Q9H4M9,P01889,O15127,O15126,Q9H223 8 +Ficolin 1 rich granule 0.4798491470228099 0.9913079067264664 0.3215352533359332 1.0 1.0 86 P15586,O75874,P04080,P16278,Q13510,Q93050,P42785,P09960,P10253,P11279,P20618,P13473 12 +Outer mitochondrial membrane protein complex 0.5227977306403992 0.9750825885252368 0.3295192946086391 1.0 1.0 16 Q13505,Q9NS69 2 +Cop9 signalosome 0.5467255365053798 0.966835859668998 0.3336260948580376 1.0 1.0 10 Q9UBW8 1 +Micos complex 0.5853085610013754 0.9528086842757664 0.3406870134309163 1.0 1.0 5 Q6UXV4 1 +Cytolytic granule 0.6124420931960581 0.9356322754629032 0.3494625509090179 1.0 1.0 4 Q15833 1 +Ficolin 1 rich granule lumen 0.4398577918254727 0.9334292391352076 0.3505983895983182 1.0 1.0 67 P15586,O75874,P35573,P04080,P25787,Q9Y376,O00231,Q13510,P16278,P08238,P07900,Q8WVQ1,P09960,Q16539,P61160,P20618,Q99436 17 +Flotillin complex 0.5426758876772431 0.9110264861214394 0.3622814184041143 1.0 1.0 6 O75955,P41440 2 +Early endosome membrane 0.395081304806525 0.908136161341934 0.3638062872006138 1.0 1.0 44 P51790,P04439,Q99816,P10321,Q86YV9,Q9H4M9,P01889,Q8IV08,Q06481,Q9HC07,Q9H223,Q15043,P04083 13 +Clathrin coated vesicle 0.3929798068673284 0.9061606406544932 0.3648508323330188 1.0 1.0 43 P11717,O43493,P42892,P50570,P09496,Q14108,O15126,Q9Y6I3,P20645,P51809,Q9BXS5,P61966,Q9NVZ3,Q5VW38 14 +Prefoldin complex 0.535259334525756 0.8784563432872853 0.3796961194378851 1.0 1.0 6 Q9UHV9,Q9NQP4,P61758 3 +Transport vesicle 0.480045694643073 0.8752277857968603 0.3814499775275342 1.0 1.0 95 O43493,P24390,Q92572,Q15437,O43731,P50897,P20645,P0DP25,Q92542,Q9BT78,Q7Z6M1,P51790,O60499,P11717,Q15907,Q7L0J3,P09496,O15027,Q9Y3B3,Q13190,Q9H0U4,P04439,O15498,O00461,O15260,P10321,P05067,O43760,P01889,O95486,O15126,P11279,P61966 33 +Ciliary plasm 0.5059190525940448 0.8604465607066937 0.3895429292153145 1.0 1.0 15 Q10713,P10644,P04350,Q9H0F7,Q96EX3 5 +Dendritic growth cone 0.7533253622836772 0.8573425104882835 0.3912556212316798 1.0 1.0 3 P08238 1 +Main axon 0.5251795165021506 0.8458177186147129 0.3976544393913572 1.0 1.0 8 P05067 1 +Intrinsic component of mitochondrial outer membrane 0.5062511532073265 0.8202756982801094 0.4120589568703661 1.0 1.0 13 Q9BWH2,P57105 2 +Neuron projection terminus 0.50480365737667 0.8131720763072616 0.4161194067864193 1.0 1.0 13 Q9UQB8 1 +Dna polymerase complex 0.5030210019074195 0.8044331096381744 0.4211468858700775 1.0 1.0 13 P56282,Q9NRG0,Q15054,Q14181 4 +Ciliary transition zone 0.5143866220558768 0.7973607649089606 0.4252415390403052 1.0 1.0 8 Q15555,Q9Y366,A6NIH7 3 +Dopaminergic synapse 0.8892307692307697 0.7939629706016935 0.4272169887131636 1.0 1.0 2 P41440 1 +Coated vesicle 0.4594212558937192 0.7908794315772829 0.4290143520735225 1.0 1.0 89 O43493,P24390,P42892,Q15437,O43731,P53634,P50570,Q9Y6I3,P20645,P51809,Q9BXS5,Q5VW38,Q9Y282,Q8N511,O95070,Q9NVZ3,P11717,Q96RQ1,P09496,Q14108,O15027,Q9Y3B3,Q13190,P04439,P10321,P05067,P01889,O95486,Q969X5,O15126,Q9NR31,P61966,Q5VYK3 33 +Alpha dna polymerase primase complex 0.5425119037416867 0.7722543200383553 0.4399638147537019 1.0 1.0 5 Q14181 1 +Cytochrome complex 0.4818392348533958 0.7602549756308606 0.4471021892826297 1.0 1.0 16 P14406,Q9UDW1 2 +P body 0.3568905601469134 0.7456346515460763 0.4558881446480978 1.0 1.0 34 P19474,P25787,Q9Y2V2,P62312,Q9HCE1,Q92600,Q96C86,P62310,P60900,Q5T6F2 10 +Outer membrane 0.4495686462293367 0.7397551327496891 0.4594485879897809 1.0 1.0 87 Q13505,Q9NZ45,Q9UKU0,Q9Y3D6,P21796,Q99536,P30536,Q9NS69,P45880,Q8N4H5,P52789,Q8WWV3,P57105,P09601,O43169,Q6NUM9,Q9HCL2,Q9BWH2 18 +Escrt i complex 0.8710769230769244 0.7357110117180639 0.461906586790537 1.0 1.0 2 Q9H9H4 1 +Phagophore assembly site 0.5008337474308354 0.7322002875555177 0.4640463288588567 1.0 1.0 7 Q9H0U4,Q6PHR2 2 +Filopodium 0.3726805184025503 0.730709242538913 0.4649567689271596 1.0 1.0 30 P05067,Q9UQB8,Q96EX3 3 +Respiratory chain complex iv 0.4922984938322126 0.713792281424234 0.4753556332099635 1.0 1.0 10 P14406,P00403 2 +Respiratory chain complex iii 0.4920565999209713 0.6942080653645303 0.4875517353442409 1.0 1.0 7 P22695,Q9UDW1 2 +Intrinsic component of plasma membrane 0.4334374298193512 0.6917349682205751 0.4891037828379996 1.0 1.0 81 O15118,Q99797,Q15375,Q14517,P33527,P20645,P27105,O43657,O60637,Q8TAD4,P0DP25,Q92542,Q8WTV0,P41440,Q9UIQ6,Q9UNK0,Q15043,P11717,O00400,O00560,O14786,P04439,O15498,P10321,P05067,P01889,Q13641,P11279,Q8N2K0 29 +Messenger ribonucleoprotein complex 0.7052297917088544 0.6871716358282941 0.4919745761551644 1.0 1.0 3 P67809 1 +Protein phosphatase 4 complex 0.7051400430901841 0.686863181650643 0.49216895041692 1.0 1.0 3 Q5MIZ7,Q6IN85 2 +Nadh dehydrogenase complex 0.4194091837204858 0.684017250496157 0.4939642728470721 1.0 1.0 24 O75380,O43676,O95182,O95168,O75306 5 +Late endosome membrane 0.3523442695250545 0.677070333807266 0.4983613303178307 1.0 1.0 36 Q99816,O15118,Q9UQN3,Q8IV08,Q9BXS4,Q14108,Q9HC07,Q9UNK0,P11279,Q9H9H4,P13473 11 +Lipid droplet 0.3434856391930164 0.6653213307968152 0.5058449901224704 1.0 1.0 32 Q01105,Q8NBX0,Q9H4M9,Q9H6V9 4 +Histone pre mrna 3 end processing complex 0.847076923076912 0.6607032398350563 0.5088026456768935 1.0 1.0 2 P67809 1 +Spindle microtubule 0.357429352601589 0.6583606051655482 0.5103064431579178 1.0 1.0 40 P53350,Q96CS2,Q7Z4H7,Q9Y496,Q15691,Q9UQN3,Q96DB5,Q8NI77,Q8IX90,O94927,Q9H6D7,P0DP25,P52732,P06493 14 +Trans golgi network 0.4063184335193936 0.6519124933220339 0.5144576249377528 1.0 1.0 68 Q10567,O43493,P50570,P20645,Q9BXS5,Q92538,O15127,Q9UNK0,Q7Z6M1,P11717,O60499,Q4J6C6,P09496,Q9UIL1,P04062,Q9C005,P05067,Q8N2H4,Q9HC07,O15126,P61966,Q5VYK3 22 +Nata complex 0.6943674976915998 0.6501300409629842 0.5156082258886168 1.0 1.0 3 Q9BXJ9,P41227 2 +Escrt complex 0.476281241731819 0.6346534280844256 0.5256544741077134 1.0 1.0 9 Q9UQN3,Q9H9H4 2 +Lateral plasma membrane 0.4309342564770196 0.6302937866124191 0.5285023874428378 1.0 1.0 21 Q8TAA9,P33527,P04083 3 +Clathrin coated vesicle membrane 0.4095488568092494 0.6225771811543369 0.5335624102569301 1.0 1.0 24 P11717,O43493,P09496,Q14108,P20645,Q9Y6I3,P61966,Q9NVZ3 8 +Nuclear inner membrane 0.445545631297222 0.6203046255260032 0.535057250204729 1.0 1.0 18 O75844,Q9H1E5 2 +Gtpase complex 0.5035417308284619 0.6140018014448388 0.5392141367935208 1.0 1.0 5 P04899,Q14344,P63096,P08754 4 +Proton transporting two sector atpase complex 0.4073224227363388 0.6088148420577761 0.5426471746547366 1.0 1.0 24 Q8N511,Q9Y487,O75964,Q15904,Q96IX5,Q93050,P56378 7 +Golgi apparatus subcompartment 0.4387360358437817 0.5815427667040219 0.5608747035580108 1.0 1.0 93 Q10567,O43493,P50570,P20645,Q9BXS5,Q10472,Q92538,Q9BXS4,O15127,Q9UNK0,Q7Z6M1,P11717,O60499,Q8NBN3,Q4J6C6,P09496,P04062,Q8N6G5,Q9C005,P04439,Q10713,O00461,P05067,Q8N2H4,Q9HC07,O15126,P61966 27 +Cell trailing edge 0.4646485462044701 0.5776771110697951 0.563482135207773 1.0 1.0 6 O75955,P41440 2 +Pigment granule 0.3845616713859962 0.5762415359719159 0.5644519337607175 1.0 1.0 61 P55209,P07237,O00560,O14773,O43852,P41440,Q92542,Q92820,P11279,Q93050,P27105 11 +Autophagosome membrane 0.443827272266071 0.5499261334338081 0.5823700387757511 1.0 1.0 15 P11279,Q9UQN3,P13473 3 +Tertiary granule membrane 0.4494510249346466 0.5383045603905443 0.5903668034693423 1.0 1.0 12 O75787,P61225,P10253,P63167,P27105,Q08722 6 +Postsynaptic specialization membrane 0.4531446166184757 0.5319809811908897 0.5947391679886163 1.0 1.0 8 P57105 1 +Collagen containing extracellular matrix 0.3542125102554075 0.5225333119341992 0.6012990589721023 1.0 1.0 29 P04080,P07602,Q08380,P04083 4 +Nucleoid 0.3297986511619287 0.509084955571187 0.6106926765765572 1.0 1.0 35 P45880,P21796 2 +Cytoplasmic stress granule 0.345621090194703 0.5058253841111202 0.6129792369697886 1.0 1.0 44 Q01085,Q14157,Q14444,Q9NR56,Q9Y5A9,Q9HCE1,P67809,P11940,P54646,Q14011,Q9UN86,Q13310,O95793,P26196,Q9BWF3,Q13283,P61978 17 +Vacuolar membrane 0.4714579309184548 0.5026045722044215 0.6152423140465477 1.0 1.0 121 Q10567,O15118,P42892,Q9UQN3,Q8IV08,P10253,P20645,P07602,P27105,Q8N511,P10619,O75503,Q9BXS4,P42785,Q92542,Q8WTV0,Q9NQX7,Q9UIQ6,P41440,Q9UNK0,Q15043,Q13137,Q8IY95,Q9H2V7,Q86YV9,Q9Y487,P11117,Q14108,P04062,Q93050,P11279,O15260,Q8NCG7,O75955,Q9HC07,O00462,P13473 37 +Microtubule associated complex 0.3626549475947277 0.5008294566673723 0.6164911527470962 1.0 1.0 54 Q7Z4H7,Q96P70,Q9H6D7,Q9UJW0,O15344,Q9Y496,O94927,P52732,Q15555,Q96CS2,Q9NSK0,P49356,Q66K74,Q8IVD9,P61163,Q13561,Q8NI77,O95793,Q96EX3 19 +External encapsulating structure 0.3250640103344874 0.5004239717195607 0.6167765776169349 1.0 1.0 33 P04080,Q08380,P04083,P07602,Q32P28 5 +Intrinsic component of synaptic vesicle membrane 0.439348315242547 0.4807973368652841 0.6306605431887278 1.0 1.0 10 O60499,Q7L0J3 2 +Dendrite cytoplasm 0.4398637946074695 0.4794340673409966 0.6316298626118901 1.0 1.0 9 Q9UQB8 1 +Peptidase complex 0.3692347174534708 0.4715138347477156 0.6372738424328819 1.0 1.0 60 P28070,O75486,Q05086,P49721,Q99436,P25787,P28074,O00231,P54725,P61289,P42575,Q9UL46,P28072,P60900,Q92530,O75832,P54727,P04632,P20618,Q9Y6J9,Q5VYK3 21 +Potassium channel complex 0.6347274105034582 0.459340109180526 0.6459899491792993 1.0 1.0 3 Q9NUT2 1 +Intrinsic component of endoplasmic reticulum membrane 0.357171485331745 0.4587572149803613 0.6464085222575404 1.0 1.0 54 Q9Y282,P10321,P01889,O75844,Q969X5,Q86XL3,Q8TB61,Q9NZ01,Q15629,O95470 10 +Microvillus membrane 0.4873768472906308 0.4532547867784249 0.6503652857760804 1.0 1.0 4 P26038,P35222,P06756 3 +Phagophore assembly site membrane 0.485932611731227 0.4483175208186895 0.6539240575868945 1.0 1.0 4 Q9H0U4 1 +Intrinsic component of mitochondrial inner membrane 0.3243222641764159 0.4352093154195579 0.6634105015363527 1.0 1.0 31 Q13505,Q9NX63,Q8NE86,O14925,Q6UXV4,P50336,Q99595,Q15070,Q96NB2,Q9H9P8 10 +Cell pole 0.6263465681748264 0.4345786338371476 0.6638683065507709 1.0 1.0 3 Q9BTU6,P35241 2 +Mcm complex 0.4254143744687523 0.4233339854582844 0.6720516017563718 1.0 1.0 6 P33993 1 +Aryl hydrocarbon receptor complex 0.7587692307692291 0.4110576764664169 0.6810302432271591 1.0 1.0 2 P08238 1 +Clathrin coated endocytic vesicle membrane 0.4158637820955091 0.4081507720161234 0.6831629869770919 1.0 1.0 14 O43493,Q14108,P20645 3 +Endocytic vesicle 0.3915803547228776 0.4003369060944683 0.6889083885942431 1.0 1.0 79 O43493,P50570,P20645,Q9H223,Q03518,Q4VCS5,Q9UNK0,Q8WTV0,P51790,P11717,Q15907,Q9H4M9,Q9Y487,P09496,Q14108,Q93050,Q6ZWJ1,P04439,O00461,P10321,P01889,P11233,Q06481,P11279,Q5VYK3,P13473 26 +Cyclin dependent protein kinase holoenzyme complex 0.4182733855892041 0.3976940425781441 0.6908557293422408 1.0 1.0 11 P06493,P11802,P12004,Q9P287 4 +Sarcolemma 0.3719112420220617 0.3973568944371664 0.691104297681683 1.0 1.0 24 O75955,Q92542,P41440,P11279,P04083 5 +Chromaffin granule membrane 0.7513846153846075 0.3925219270973719 0.6946726131616581 1.0 1.0 2 P30626 1 +Golgi membrane 0.4827353535254217 0.3670183553479736 0.7136053264146185 1.0 1.0 142 Q10567,Q93063,P24390,O43731,P50570,Q8IV08,Q8IZA0,Q9BXS5,Q10472,Q6UWU4,Q9P2W9,Q9H7Z7,Q9Y282,Q8N6T3,Q92538,Q9BXS4,P52292,O95070,O43505,P51790,O60499,P11717,Q8NBN3,O00400,Q14108,Q9Y3E0,O15027,Q9Y3B3,Q9UIL1,Q8NCH0,Q8N6G5,Q13190,Q92896,Q9H0U4,P04439,Q10713,O15498,O00461,O15260,P10321,P01889,Q15392,Q8N2H4,Q969X5,Q9HC07,Q9H8Y8,Q8TB61,P61966 48 +Pericentriolar material 0.6020816725805651 0.3663069358038877 0.7141360547140403 1.0 1.0 3 Q86VS8 1 +Er to golgi transport vesicle membrane 0.3758690371240546 0.3573742702583545 0.7208116360408652 1.0 1.0 22 P04439,P10321,Q15437,P01889,O15027,Q9Y3B3,O95486,Q13190 8 +Lumenal side of endoplasmic reticulum membrane 0.4082271617553887 0.3569181590180738 0.7211530749107389 1.0 1.0 7 P10321,P01889 2 +Endoplasmic reticulum chaperone complex 0.4031486342785028 0.3386068814238777 0.734905897920894 1.0 1.0 7 Q9UBS4 1 +Vesicle lumen 0.441074323782157 0.3293665983189096 0.7418786112764448 1.0 1.0 117 P06280,P04066,Q08380,P15586,Q8NBM8,P16278,Q9NTK5,P10619,P02792,O75874,P61916,Q99536,P17900,O00560,Q8NBX0,P04080,P05067,Q9BTY2,O00584,P20618 20 +Inner mitochondrial membrane protein complex 0.3763933279559001 0.3268061516232763 0.7438145063747514 1.0 1.0 76 P14406,Q13505,O75380,P00403,O43676,Q9UDW1,O75306,O75964,Q99595,O95168,O95182,Q96IX5,Q9Y6M9,P56378,Q9Y584 15 +Late endosome 0.3502618574651793 0.3068755458140118 0.7589381031841889 1.0 1.0 62 P11717,Q8IY95,Q99816,P11279,O15118,Q9UQN3,Q15043,P10644,Q8IV08,Q9BXS4,Q14108,P20645,Q9HC07,Q9UNK0,P07602,Q9H9H4,P13473 17 +Cdc73 paf1 complex 0.412983252332495 0.2910211826564299 0.7710351189143432 1.0 1.0 5 Q92541 1 +Transcription factor tfiid complex 0.3889060092449958 0.2890029881750754 0.7725790908540586 1.0 1.0 7 P23193,P18074,P19447,P29083,Q9Y6J9,Q00403 6 +Eukaryotic translation initiation factor 2b complex 0.3852973951536053 0.2815494958863224 0.7782889704674691 1.0 1.0 6 Q9UI10 1 +Cd95 death inducing signaling complex 0.7024615384615427 0.2809554884607986 0.7787445402805193 1.0 1.0 2 P49327 1 +Myelin sheath 0.3881209942032745 0.2803455155106323 0.779212433868117 1.0 1.0 11 P04350,P31150,P0DP25,Q8IXJ6 4 +Sperm annulus 0.7018461538461551 0.2796843243007754 0.7797197059572092 1.0 1.0 2 Q15019 1 +Cell tip 0.6984615384615375 0.2727544673509874 0.7850419625903469 1.0 1.0 2 Q9BTU6 1 +Clathrin coated endocytic vesicle 0.3739998093899604 0.2702983636263167 0.7869307241596202 1.0 1.0 18 P11717,O43493,Q14108,P50570,P09496,P20645 6 +Intrinsic component of mitochondrial membrane 0.3188306268400419 0.2660110021325697 0.7902307357373322 1.0 1.0 47 Q13505,Q9Y3D6,P50336,Q99595,P57105,Q9BWH2 6 +Mhc class i peptide loading complex 0.4254332184597785 0.2626271539674111 0.7928379686920797 1.0 1.0 4 Q03518 1 +Crd mediated mrna stability complex 0.3687715656759922 0.2292810625778399 0.8186504713379357 1.0 1.0 6 P67809 1 +Site of polarized growth 0.304713188045904 0.2280468805154691 0.8196097951877845 1.0 1.0 42 Q8IYI6,Q13561,P08238,P05067,Q13509,P50570,P51114,P0DP25,Q9UPT5,Q96A49,Q8IXJ6,Q9UKA9 12 +Exocyst 0.3692897685477854 0.2253372678129979 0.8217169095684445 1.0 1.0 7 Q9UPT5 1 +Endoplasmic reticulum palmitoyltransferase complex 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Palmitoyltransferase complex 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Early endosome 0.3854136137694126 0.2029832204415155 0.8391481473511904 1.0 1.0 93 Q8IV08,Q9H223,Q5VW38,Q99816,Q13510,Q92542,P41440,Q9UNK0,Q9UIQ6,Q15043,P51790,P11717,Q9Y5X3,Q9H4M9,Q86YV9,P04083,O14786,P04439,P10321,O75955,P05067,P01889,Q06481,Q9HC07 24 +Multivesicular body 0.3651358371136506 0.2007402283649735 0.8409017022379826 1.0 1.0 13 P10644,P11279,Q9UQN3 3 +Anchored component of plasma membrane 0.6572307692307716 0.1969293094891097 0.8438828571157322 1.0 1.0 2 P36551 1 +Mmxd complex 0.5258888747750513 0.1908456840815222 0.8486464957011479 1.0 1.0 3 Q96T76 1 +Extrinsic component of postsynaptic membrane 0.3937210575498274 0.1848779785667249 0.8533247437889995 1.0 1.0 4 P52292,P46109 2 +Stereocilium bundle 0.371581026480947 0.1765209861891497 0.8598846629499644 1.0 1.0 5 Q14651 1 +Dynactin complex 0.3708620963603002 0.1747672292340628 0.8612625392697375 1.0 1.0 5 Q9UJW0,P61163 2 +Adherens junction 0.2948427241359904 0.1730119405913273 0.8626420419273526 1.0 1.0 41 O75955,O00560,Q9UQB8,P41440,P04083,P31949 6 +Mib complex 0.3547155774313825 0.1687554956271328 0.8659889655033499 1.0 1.0 10 Q13505,Q9Y512,Q6UXV4,Q9NX63 4 +Photoreceptor connecting cilium 0.347290924118376 0.1676756812535172 0.8668384288448192 1.0 1.0 6 O15078,Q15555,Q9Y366,Q15019 4 +Ccr4 not complex 0.3658414416046445 0.1627557208127524 0.8707107729761001 1.0 1.0 5 O95628 1 +Dense core granule 0.5092277719804026 0.1613035111821277 0.871854357951336 1.0 1.0 3 Q709C8 1 +Brisc complex 0.3825077353435123 0.161054839896034 0.8720502083644952 1.0 1.0 4 Q15018 1 +Intrinsic component of peroxisomal membrane 0.345883001696574 0.1573298492261992 0.8749848969082012 1.0 1.0 7 Q9Y3D6,O14975 2 +Anchored component of membrane 0.3442218798150941 0.1528589668852489 0.8785094952270658 1.0 1.0 7 P36551,Q9NQX3,P20339,Q9ULX3,P51149,P61020 6 +Retromer complex 0.3435090965155837 0.1400221003437187 0.8886425288566837 1.0 1.0 9 Q9Y5X3,O75436,Q9UBQ0,O60749,O60493,Q9UNH7,Q9UMY4,Q13596 8 +Extrinsic component of endosome membrane 0.3531788823210116 0.1343217023764481 0.8931481927344362 1.0 1.0 5 P04083 1 +T tubule 0.3319438194229728 0.1284401658041999 0.8978006466563488 1.0 1.0 6 P30626,P35241 2 +Centriolar subdistal appendage 0.4874975826833796 0.1277498135476157 0.8983469675108438 1.0 1.0 3 Q5SW79 1 +Schaffer collateral ca1 synapse 0.3413390481958668 0.1240551959810458 0.9012715724734732 1.0 1.0 15 Q9UQB8 1 +Mpp7 dlg1 lin7 complex 0.6036923076923137 0.1227326761756102 0.9023187876251388 1.0 1.0 2 Q5T2T1 1 +Wnt signalosome 0.6000000000000063 0.1186104144547944 0.9055840140609686 1.0 1.0 2 P49841 1 +Microbody membrane 0.2779904010901322 0.1178714614252021 0.9061695060640852 1.0 1.0 31 Q99614,O00116,Q9UKU0,Q9Y3D6,P04035,P50542,Q15067,P51648,Q9Y5Y5,Q5T8D3,O14975 11 +Intraciliary transport particle b 0.4775935869095128 0.114306669825253 0.9089946954012094 1.0 1.0 3 Q9Y366 1 +Intraciliary transport particle 0.4775935869095128 0.114306669825253 0.9089946954012094 1.0 1.0 3 Q9Y366 1 +Ikappab kinase complex 0.4770698676515894 0.1136275465534503 0.909533049778755 1.0 1.0 3 O14920,Q8IUD2 2 +Extrinsic component of endoplasmic reticulum membrane 0.5941538461538444 0.1123362017683137 0.9105568385950832 1.0 1.0 2 O14656 1 +Neuron spine 0.3037443722279641 0.0954646249707876 0.9239457870809944 1.0 1.0 26 Q9UQB8 1 +Outer kinetochore 0.3207951667717818 0.0951402561898784 0.9242034232640716 1.0 1.0 7 P53350,Q96EA4,Q8IX90 3 +Tubular endosome 0.3429802955664902 0.0929040223299466 0.92597981021363 1.0 1.0 4 O75436,Q9UNH7,Q9Y5X3 3 +Trans golgi network transport vesicle membrane 0.3300133910761151 0.089341424193896 0.9288105739301372 1.0 1.0 5 P61966 1 +Sin3 complex 0.3322044334975246 0.0785402619579931 0.93739830470709 1.0 1.0 4 Q9UBU8,Q92769,Q13547 3 +Postsynaptic recycling endosome 0.4404432132964039 0.0737226318258809 0.9412310901962198 1.0 1.0 3 P20338,Q4V328 2 +Dna replication preinitiation complex 0.3159863039811744 0.0711933456028194 0.94324387741956 1.0 1.0 9 P33993,Q9BRT9 2 +Ciliary basal body 0.3186604413912939 0.0706714238245334 0.943659264438366 1.0 1.0 20 O43805,Q96EX3,Q9Y366,P28070 4 +Chromaffin granule 0.4358366617989356 0.069711619417904 0.944423193325308 1.0 1.0 3 P30626 1 +Vacuole 0.5236512401602974 0.0653040110609447 0.9479319487989488 1.0 1.0 211 P06280,P19474,Q10567,O15118,Q9UM22,P04066,P42892,Q9UQN3,P50897,Q8IV08,P10253,P20645,P07602,Q6PHR2,P27105,P15586,Q9UMR5,Q9H7Z7,Q8IW92,Q8NCC3,Q8N511,Q13510,P16278,P06865,P10619,Q8NHP8,O75503,Q9BXS4,P42785,O14773,Q92542,Q8WTV0,P02792,Q9UIQ6,Q9NQX7,P41440,Q9UNK0,Q9UHG3,Q15043,Q13137,Q8IY95,P61916,Q99536,P17900,Q9H2V7,Q86YV9,Q9Y487,P11117,Q14108,O00560,P04062,O00754,Q93050,P54802,Q92820,P11279,O15260,Q8NCG7,O75955,O43681,Q15833,Q9HC07,Q9NX40,Q9BTY2,O00462,O00584,Q5BJF2,P13473 68 +Brca1 a complex 0.4281925938307409 0.0635167639920414 0.949355010462226 1.0 1.0 3 Q9NWV8 1 +Dynein complex 0.3181608243208287 0.0614592757694636 0.9509934462926096 1.0 1.0 12 Q13561,Q8IVD9,Q9UJW0,Q96FJ2,Q96EX3 5 +Axonal growth cone 0.3112399542532391 0.0595821832399932 0.9524884088698587 1.0 1.0 5 P08238 1 +Perikaryon 0.3167457365228561 0.0580123913898549 0.953738758249004 1.0 1.0 19 Q96A49,P05067,P63244,Q8IXJ6 4 +Extrinsic component of synaptic membrane 0.3036693425391834 0.0492377775941213 0.96072980559666 1.0 1.0 5 P52292,P46109 2 +Axon initial segment 0.496615384615393 0.0473983586256902 0.9621957371787396 1.0 1.0 2 P78559 1 +Basal cortex 0.4821538461538566 0.0428405320348509 0.9658286537413844 1.0 1.0 2 O75122 1 +Ribose phosphate diphosphokinase complex 0.476307692307704 0.0412636526899216 0.967085709328288 1.0 1.0 2 Q14558 1 +Cytoplasmic dynein complex 0.3047211121706647 0.0411106484005182 0.9672076855854066 1.0 1.0 10 Q8IVD9,Q96FJ2,Q96EX3,Q9UJW0 4 +Ribbon synapse 0.3890427823945878 0.0398922040984746 0.9681790663855636 1.0 1.0 3 P11142,P56545 2 +Death inducing signaling complex 0.3864358610549283 0.0387441579761534 0.9690943668475732 1.0 1.0 3 P49327 1 +Cul4a ring e3 ubiquitin ligase complex 0.445846153846155 0.0351084128886763 0.9719932930342188 1.0 1.0 2 Q92990 1 +Ap 3 adaptor complex 0.3765661658829617 0.0348086102671236 0.9722323547933168 1.0 1.0 3 Q92572 1 +Sperm head 0.3709461360490145 0.0328405196735294 0.973801765599836 1.0 1.0 3 P08238 1 +Trans golgi network transport vesicle 0.3033674041988452 0.032653261443963 0.9739510959605366 1.0 1.0 11 O43493,P11717,P61966 3 +Manchette 0.4175384615384721 0.0317676970278512 0.9746573076650352 1.0 1.0 2 Q96SI9 1 +Shelterin complex 0.4027692307692266 0.0306603114430686 0.9755404431504152 1.0 1.0 2 Q15554 1 +Lamellar body 0.4003076923076883 0.0305085429408864 0.9756614802722694 1.0 1.0 2 Q07065 1 +Protein complex involved in cell adhesion 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 +Integrin complex 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 +Cuticular plate 0.3750769230769194 0.0293721671648938 0.9765677706088198 1.0 1.0 2 Q9Y5X1 1 +Neuronal dense core vesicle 0.2726153846153745 0.0283226085183334 0.9774048488412485 1.0 1.0 2 Q96RL7 1 +Wash complex 0.2721674876847222 0.0274172637447931 0.9781269289473002 1.0 1.0 4 Q12768,P47756,P52907 3 +Distal axon 0.2895239023935553 0.0270076896287205 0.9784536008329912 1.0 1.0 52 P51790,Q8IYI6,P05067,Q13509,P50570,P51114,Q13641,P0DP25,Q9UPT5,Q96A49,Q8IXJ6,Q9UKA9 12 +Clathrin vesicle coat 0.3010150876663206 0.0226422487153165 0.9819356428546696 1.0 1.0 12 P61966,Q9Y6I3,Q9NVZ3 3 +Septin cytoskeleton 0.2515394088669841 0.0188964498491755 0.9849237116463596 1.0 1.0 4 Q16181,Q9UHD8,Q15019 3 +Signal recognition particle 0.275639051432088 0.0187128884727111 0.9850701465412754 1.0 1.0 5 P37108,Q9UHB9,P49458,P61011 4 +Elongator holoenzyme complex 0.2671591258848929 0.018568202851115 0.9851855689101724 1.0 1.0 3 Q6IA86,Q9H9T3 2 +Presynaptic active zone 0.3024441286950463 0.0128152501549796 0.9897751896304672 1.0 1.0 16 O75955,P05067,P41440 3 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ad5c46d0e318a4bf7f498ad4c85087cf6d95ec45 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Glycosylphosphatidylinositol n acetylglucosaminyltransferase gpi gnt complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner acrosomal membrane", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Smad protein complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC10", "ARMC9", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG9A", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C18orf32", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "C3orf58", "C6orf89", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP2", "CAST", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC94", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CMPK1", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG4", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCK", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM126A", "FAM162A", "FAM207A", "FAM208A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FNTB", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA3", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK3", "HP1BP3", "HPF1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MGAT1", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NF1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PAOX", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCOC", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAMM41", "TAOK1", "TAP1", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TKT", "TLE3", "TLN1", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC5", "TRIM21", "TRIM25", "TRIM28", "TRIM32", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGGT1", "UHRF1", "ULK3", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRAP53", "WRAP73", "WRN", "WRNIP1", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZCCHC11", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZNF131", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB8", "ABCC1", "ABHD12", "ABRAXAS2", "ACBD5", "ACOX1", "ACP2", "ACSL6", "ACTR1A", "ACTR2", "AGL", "AGPS", "ALDH3A2", "AMOT", "ANKLE2", "ANXA1", "AP1B1", "AP1M1", "AP1S1", "AP3S1", "APLP2", "APOOL", "APP", "ARFGAP1", "ARL6", "ASAH1", "ASNA1", "ATP5L", 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1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.000291319303006 1.3710267859167043e-06 2.305276824311179e-05 0.0008110696558398 0.0100261737850475 +Serine type exopeptidase activity 4 7 2.645267618354729 0.0081626331580191 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 2.528768762805071e-07 0.0007972103198291 9.525189028353195e-09 9.707603936113732e-07 2.9438380117440665e-05 +Ceramide binding 3 5 2.574413230411198 0.0100410268722144 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 7.323130554406388e-05 3.260682492863553e-07 5.5913743904608274e-06 0.0002086676392486 0.0028454446322632 +Glycolipid binding 3 10 2.516771249582556 0.0118435695557681 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 0.0002299143945716 6.765318543664244e-05 1.806422085995589e-05 0.0006430769062578 0.0081061493093791 +Serine type carboxypeptidase activity 3 5 2.4823609679706653 0.0130514988452705 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 5.758824600398199e-07 0.0002241871259369 4.151068855161726e-08 1.7035552164727766e-06 2.725609341406673e-05 +Steroid binding 7 21 2.4207225249249484 0.0154896956518448 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0002778921878684 0.0230489069918226 0.0012677167474155 2.144160894221409e-05 0.0005336859982491 +Phosphatidylcholine binding 3 9 2.405330484040204 0.0161578462715918 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0001784044088693 0.0026008925831016 1.391730242568295e-05 0.0005013179159177 0.0064441294348778 +Cargo receptor activity 3 7 2.240094140317177 0.025084811876844 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0016852344248444 1.0 0.0299460957191466 0.0044816860022438 0.0457284836366409 +Hexosaminidase activity 2 5 2.2238462112730017 0.0261587930524058 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 0.0004925675778475 1.0 0.0032139762811053 0.0010839430889874 0.0078439900678865 +Cholesterol binding 5 13 2.2173258575234285 0.0266008321580066 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0002080030833496 0.0090330503435184 0.0029806631250197 7.247226898647767e-05 0.0004908209100213 +Palmitoyl protein hydrolase activity 3 5 2.194939982141149 0.0281679032884372 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0201641140768861 0.0014481500629001 0.0057815105752346 0.0026887292270871 0.0020484591711739 +Vitamin transmembrane transporter activity 3 7 2.181763489136875 0.0291269924891948 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0049532633265819 0.0875404472016038 0.0143328298354406 0.0104402688493973 0.0122181482786312 +Amide transmembrane transporter activity 4 6 2.138073203181289 0.0325108024139724 1.9781553398058251 4.745145631067961 1.408683964326367 0.195466717632665 1.3391087077639925 1.811666809674734 1.0002201259794938 0.2223338014085611 0.0526852742365325 0.0919337377678228 0.1774332758731671 0.0846217526668656 0.0023126937267731 +Carboxypeptidase activity 3 12 2.12846394730641 0.0332986360677349 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 0.0009269285327108 0.0058373227860703 7.654983120717976e-05 0.00251045639703 0.0053941913939985 +Sterol binding 5 16 2.092780435689401 0.0363687590549213 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0005026455166155 0.0128452267182733 0.005026170722063 0.0002102890879582 0.0015605407457041 +Wide pore channel activity 2 5 2.0905923829365363 0.03656461914467 2.157766990291262 4.266990291262136 1.156945559067054 0.1661436788367006 1.073449599559222 0.4792567768515825 1.4176309163665306 0.2377490100494037 0.0089834073950196 0.0006219606051344 0.0025156479029566 0.0150927838189798 0.00542484368483 +Peptide antigen binding 4 5 2.0905224109885414 0.0365708973737799 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.2459935349754131 1.0 1.0 0.0052676758380378 0.000548875622046 +Organic acid transmembrane transporter activity 9 24 2.0764085131381416 0.037856184560945 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0086104278093836 0.2801168002074996 0.028249351231176 0.0061759775127424 0.0056294995695267 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 7 28 2.0680345719745388 0.0386367722876468 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0954554928929811 0.3624074851394556 0.2282562036879738 0.0770567400392524 0.0847202359897821 +Sulfur compound transmembrane transporter activity 4 9 2.054699230534089 0.0399080643229912 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.1010980461695073 0.1305522111527444 0.2467424796819782 0.0051006501172469 0.0123302080146435 +Metallopeptidase activity 16 42 2.039252363848329 0.0414248472319154 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0037108677560947 0.3208381238265493 0.0426450873703444 0.0007188477633907 6.264710393938845e-06 +Signal sequence binding 3 29 2.019318993431643 0.0434540750114653 5.560679611650485 26.50242718446602 0.435828138514089 0.5798441286349703 3.257360227950366 2.1761045475756564 0.8353222176818301 0.3288364338889158 0.0063238528581457 0.0009094910101507 0.0005845317815958 0.0159331781494728 0.0441585606865437 +Antigen binding 4 6 2.0143913085445617 0.0439684661576644 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.3515141317449456 1.0 1.0 0.017764157863851 0.0044460825905537 +Quaternary ammonium group binding 3 13 2.0130192488274123 0.0441126043841402 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0006569512931241 0.0049155620827658 5.34886142038437e-05 0.0017956484300789 0.0036228880175549 +Threonine type endopeptidase activity 4 8 2.011419511810239 0.0442811641003138 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0006940358493172 0.0470522829573702 0.0039921150854813 0.0015206572897169 5.650922597265324e-05 +Phosphatase regulator activity 13 27 2.0061528869323366 0.0448399386901243 5.890776699029126 21.42718446601942 0.2207502835350587 0.5696921397829399 3.3115291951500065 3.3518635354302604 0.8778999195679603 0.2968997706719961 0.434909530334173 1.0 0.538739338785351 0.1272831365513204 0.0146767072181177 +Voltage gated anion channel activity 4 7 2.0050168084198043 0.0449612501430063 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0140881930731448 0.0009934566258862 0.0039921150854813 0.0234889728544392 0.000939912047649 +Cytokine activity 0 5 2.000928646735632 0.0454000799054876 1.4368932038834952 5.75 0.9689346120623524 0.3423153019744804 1.105326054892273 0.6058973927039436 0.8855586242183912 0.2854448354224685 0.3636258308638302 0.1093006244161378 0.208984012191681 0.4479222530759854 0.7005145441184911 +Threonine type peptidase activity 4 9 1.9952112073209969 0.0460198492201564 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.0019925604751186 0.0652597674910206 0.0078714328443906 0.0042908003473226 0.0003811527509218 +Cytoskeletal anchor activity 1 6 1.991934643333184 0.046378229286526 1.4587378640776698 6.114077669902913 0.7031806656642005 0.4219849600096998 1.2250406607966715 1.3434833271306592 0.8879018057008594 0.290790264904966 0.0479915779418294 1.0 0.0143328298354406 0.0773660358903978 0.2376866166417752 +Organic anion transmembrane transporter activity 7 35 1.982399790595168 0.0474345130220215 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.2110082329624573 0.3371313972628795 0.1997425917545389 0.017553407397255 0.0227409192206126 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..21642470d10a643ab6752127c0cd79cf46a4e341 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 1389, + "title": "Average number of proteins per term", + "value": 16.809935205183585 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ef0c27978f739682ff37fc1bb244f575427a0b4d --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..69107490339935373d1c5c830ce57c1ddbeb3663 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,412 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Exopeptidase activity 0.6874584603056261 3.3602317868227995 0.0007787710617099 0.6611285431747455 0.5408565023575831 33 P53582,P55786,P10619,Q9HB40,Q9H3G5,O75844,P42785,P09960,O14773,Q9NZ08,Q92820,Q9UIQ6 12 +Hydrolase activity acting on glycosyl bonds 0.6547671788465501 2.840173483671156 0.0045089005449259 0.9981210172810602 0.6863181102873737 30 P06280,P54802,Q8IW92,P16278,P06865,P04066,P17900,Q9NUJ1,O75503,P10253,P04062,O00754,O00462,Q9BTY2 14 +Hydrolase activity hydrolyzing o glycosyl compounds 0.8029344855785885 2.7499173313536667 0.0059610301460275 0.9997526355160016 0.6863181102873737 21 P06280,P54802,Q8IW92,P16278,P04066,P06865,P17900,P10253,P04062,Q9BTY2,O00462 11 +Sphingolipid binding 0.952159870322738 2.6502182139661303 0.0080439797525795 0.9999865733413132 0.6863181102873737 6 P45880,P21796,Q9UM22 3 +Serine type exopeptidase activity 0.9433950693937856 2.645267618354729 0.0081626331580191 0.9999886287732948 0.6863181102873737 7 P10619,Q9HB40,P42785,O14773 4 +Ceramide binding 0.9737749593068628 2.574413230411198 0.0100410268722144 0.9999991828798072 0.6863181102873737 5 P45880,P21796,Q9UM22 3 +Glycolipid binding 0.8870695907318801 2.516771249582556 0.0118435695557681 0.9999999350021604 0.6863181102873737 10 P50897,P07602,Q9UM22 3 +Serine type carboxypeptidase activity 0.9501865670561672 2.4823609679706653 0.0130514988452705 0.9999999881136326 0.6863181102873737 5 P10619,Q9HB40,P42785 3 +Steroid binding 0.7408214930444146 2.4207225249249484 0.0154896956518448 0.9999999996172196 0.6863181102873737 21 P61916,O15118,P21796,P30536,P45880,Q14108,P04062 7 +Phosphatidylcholine binding 0.8690006690009449 2.4053304840402037 0.0161578462715918 0.9999999998509208 0.6863181102873737 9 Q00169,P45880,P21796 3 +Cargo receptor activity 0.8435337334267194 2.240094140317177 0.025084811876844 0.9999999999999996 0.6863181102873737 7 Q14108,Q8WTV0,O15260 3 +Hexosaminidase activity 0.8852542774655309 2.2238462112730017 0.0261587930524058 1.0 0.6863181102873737 5 P54802,P17900 2 +Cholesterol binding 0.7923869042890204 2.2173258575234285 0.0266008321580066 1.0 0.6863181102873737 13 O15118,P21796,P30536,P45880,Q14108 5 +Palmitoyl protein hydrolase activity 0.8781087578132153 2.1949399821411495 0.0281679032884372 1.0 0.6863181102873737 5 P50897,Q9UMR5,Q9NUJ1 3 +Vitamin transmembrane transporter activity 0.8295496898900598 2.181763489136875 0.0291269924891948 1.0 0.6863181102873737 7 Q9H2D1,P33527,P04062 3 +Amide transmembrane transporter activity 0.824686702843353 2.138073203181289 0.0325108024139724 1.0 0.6863181102873737 6 Q9H2D1,P33527,P41440,Q03518 4 +Carboxypeptidase activity 0.7817758247425833 2.12846394730641 0.0332986360677349 1.0 0.6863181102873737 12 P10619,Q9HB40,P42785 3 +Sterol binding 0.7376204501772365 2.092780435689401 0.0363687590549213 1.0 0.6863181102873737 16 O15118,P21796,P30536,P45880,Q14108 5 +Wide pore channel activity 0.8524962929653521 2.0905923829365363 0.03656461914467 1.0 0.6863181102873737 5 P45880,P21796 2 +Peptide antigen binding 0.8524792115799159 2.0905224109885414 0.0365708973737799 1.0 0.6863181102873737 5 Q15392,P01889,P10321,Q03518 4 +Organic acid transmembrane transporter activity 0.6388139577909974 2.0764085131381416 0.037856184560945 1.0 0.6863181102873737 24 Q9BQT8,Q96H78,Q9UBX3,Q9H2D1,P33527,P41440,Q9Y619,P08183,O14975 9 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.578321557378469 2.0680345719745388 0.0386367722876468 1.0 0.6863181102873737 28 P30519,O15460,Q32P28,P09601,Q16850,Q9NVH6,Q6UW02 7 +Porin activity 0.8813518104606566 2.0581749925596364 0.0395733382523593 1.0 0.6863181102873737 4 P45880,P21796 2 +Sulfatide binding 0.8805824503100416 2.055058278028077 0.039873376108396 1.0 0.6863181102873737 4 P50897 1 +Sulfur compound transmembrane transporter activity 0.7874238205119691 2.054699230534089 0.0399080643229912 1.0 0.6863181102873737 9 Q9UBX3,Q8TB61,P33527,Q70HW3 4 +Metallopeptidase activity 0.5289287528603904 2.0392523638483295 0.0414248472319154 1.0 0.6863181102873737 42 Q10713,Q6P179,Q99797,P55786,P42892,P22695,Q7Z2K6,P53582,Q9BYT8,O75844,P09960,Q9NZ08,O00303,Q9UIQ6,Q96KP4,O43847 16 +Signal sequence binding 0.5555364931547899 2.019318993431643 0.0434540750114653 1.0 0.6863181102873737 29 P24390,Q6UWU4,O43731 3 +Antigen binding 0.7950320909171967 2.0143913085445617 0.0439684661576644 1.0 0.6863181102873737 6 Q15392,P01889,P10321,Q03518 4 +Quaternary ammonium group binding 0.7487073360145955 2.0130192488274123 0.0441126043841402 1.0 0.6863181102873737 13 Q00169,P45880,P21796 3 +Threonine type endopeptidase activity 0.7836506869700209 2.011419511810239 0.0442811641003138 1.0 0.6863181102873737 8 P49721,P20618,P28070,P28072 4 +Phosphatase regulator activity 0.5845544556230595 2.0061528869323366 0.0448399386901243 1.0 0.6863181102873737 27 Q01105,O43768,Q9C0I1,P63151,Q15257,P30154,Q12972,Q86XL3,P0DP25,P78318,Q5MIZ7,O94766,Q9Y570 13 +Voltage gated anion channel activity 0.7877339166470197 2.0050168084198043 0.0449612501430063 1.0 0.6863181102873737 7 Q9Y277,P51797,P45880,P21796 4 +Threonine type peptidase activity 0.7738971251979366 1.9952112073209969 0.0460198492201564 1.0 0.6863181102873737 9 P49721,P20618,P28070,P28072 4 +Cytoskeletal anchor activity 0.7896907444504104 1.9919346433331837 0.046378229286526 1.0 0.6863181102873737 6 Q9UQB8 1 +Organic anion transmembrane transporter activity 0.5072485994839598 1.9823997905951676 0.0474345130220215 1.0 0.6863181102873737 35 Q8TB61,Q9UBX3,Q86VD7,Q9H2D1,P33527,P41440,Q9Y619 7 +Isocitrate dehydrogenase activity 0.8603626122065793 1.9728272463127532 0.0485152478193291 1.0 0.6871225153078545 4 P48735 1 +Transition metal ion transmembrane transporter activity 0.8208066490930517 1.9599240690379385 0.0500046659111252 1.0 0.6871225153078545 5 Q9HD20,Q9HC07,Q8TAD4 3 +Organic cation transmembrane transporter activity 0.7791340918453364 1.947392592954023 0.0514876854033135 1.0 0.6871225153078545 6 O43772,Q70HW3 2 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.779037835710524 1.9469854931029251 0.0515364739005024 1.0 0.6871225153078545 6 Q8NBM8,Q9UHG3,P07237,Q6ZRP7 4 +Beta n acetylhexosaminidase activity 0.8537773403777814 1.945915484956659 0.0516648925425529 1.0 0.6871225153078545 4 P17900 1 +Tap binding 0.8522167487684713 1.939528682828916 0.0524369954086627 1.0 0.6871225153078545 4 Q03518,P10321,P01889 3 +G protein alpha subunit binding 0.8493268969401259 1.9276925968827303 0.0538933734750575 1.0 0.6986408079270723 4 P80303 1 +Serine hydrolase activity 0.6607662375562071 1.912893222040854 0.0557617234656495 1.0 0.7041184899435203 20 P10619,Q9H3G5,Q9HB40,P42785,O14773 5 +Monooxygenase activity 0.7542633325593886 1.883235031797848 0.0596685234930332 1.0 0.7057178653910823 8 P30519,Q6UW02,P09601 3 +Modified amino acid transmembrane transporter activity 0.799110713705307 1.8695031550475256 0.0615528450984814 1.0 0.7057178653910823 5 Q9H2D1,P33527 2 +Peptide alpha n acetyltransferase activity 0.798864784883592 1.8684738895117532 0.0616960462740827 1.0 0.7057178653910823 5 Q86UY6,Q14CX7 2 +Gdp dissociation inhibitor activity 0.797635654276314 1.8633282855350783 0.0624160929108825 1.0 0.7057178653910823 5 P52565,P55010 2 +Molecular transducer activity 0.547812691764458 1.8557771713943432 0.0634853257650556 1.0 0.7057178653910823 28 P11717,O15173,O15118,P30536,Q15375,Q14108,Q4VCS5,P20645,Q8WTV0,O14786,Q15629 11 +Metalloaminopeptidase activity 0.7150971679314078 1.852799983549242 0.0639110326055165 1.0 0.7057178653910823 13 P53582,P55786,P09960,Q9NZ08,Q9UIQ6 5 +Tetrapyrrole binding 0.6676677772077411 1.8353037106224597 0.0664607015895133 1.0 0.7057178653910823 18 O15173,P30519,Q8WUJ1,P09601,O43169,Q6UW02 6 +Aminopeptidase activity 0.6952295689960765 1.8346471721396584 0.0665579844249328 1.0 0.7057178653910823 15 P53582,P55786,P09960,Q9NZ08,Q9UIQ6 5 +Protease binding 0.4812492523116142 1.8226763639988175 0.0683524221773486 1.0 0.7150580388681429 32 P04080,O75955,P54725,P46379,P41440,P07602,Q15650,Q9UDY8 8 +Lipid transfer activity 0.7436857320215888 1.8151680923994211 0.0694980815314609 1.0 0.7150580388681429 7 P30536,Q00169 2 +Voltage gated channel activity 0.7086914401454671 1.7874693134518254 0.0738616675400671 1.0 0.7380852964975059 12 Q9Y277,P51797,P45880,P21796 4 +Lipid transporter activity 0.6144119774931526 1.7777530090684224 0.0754444293088967 1.0 0.7396282559925788 22 O15118,P30536,P17900,Q00169,P33527,P08183 6 +Acid phosphatase activity 0.7770313924974914 1.776724715223983 0.0756135438091765 1.0 0.7396282559925788 5 Q9NPH0 1 +Anion transmembrane transporter activity 0.5166728801692431 1.7662417634785397 0.0773552971939153 1.0 0.7513741804360026 53 P21796,O00400,Q9BQT8,O43681,P45880,Q9Y277,Q9UBX3,Q8TB61,Q86VD7,Q9H2D1,P33527,P41440,Q15043,Q9Y619 14 +Protein phosphatase regulator activity 0.5877101049191622 1.7610987353616383 0.0782216930491976 1.0 0.7545134142037193 24 Q01105,O43768,P63151,Q15257,P30154,Q12972,Q86XL3,P0DP25,P78318,Q5MIZ7,O94766,Q9Y570 12 +Manganese ion transmembrane transporter activity 0.8012829136273395 1.7292572456780957 0.0837630648961149 1.0 0.7759374779621949 4 Q9HD20,Q9HC07 2 +Palmitoyltransferase activity 0.7640752124520203 1.7219451740891745 0.085079450642262 1.0 0.7759374779621949 5 P23786,O15498 2 +Peptidyl proline dioxygenase activity 0.7989532019704404 1.7195606681097406 0.0855123308570684 1.0 0.7759374779621949 4 O15460,Q32P28,P07237 3 +Procollagen proline dioxygenase activity 0.7989532019704404 1.7195606681097406 0.0855123308570684 1.0 0.7759374779621949 4 O15460,Q32P28,P07237 3 +Serine type endopeptidase inhibitor activity 0.7217255061333107 1.701620533330671 0.0888265258101044 1.0 0.7759374779621949 6 P05067,Q06481 2 +Lysophosphatidic acid binding 0.9759486099485976 1.698109942540188 0.0894870133920244 1.0 0.7759374779621949 3 P50897 1 +Organophosphate ester transmembrane transporter activity 0.6549503211494377 1.6723747637768052 0.0944504452438899 1.0 0.7759374779621949 16 Q9BSK2,Q86VD7,Q9H2D1,P41440,Q8TB61 5 +Nucleotide transmembrane transporter activity 0.6549503211494377 1.6723747637768052 0.0944504452438899 1.0 0.7759374779621949 16 Q9BSK2,Q86VD7,Q9H2D1,P41440,Q8TB61 5 +Inositol phosphate phosphatase activity 0.7458673541258285 1.644569250541623 0.1000586724066456 1.0 0.7759374779621949 5 Q10713 1 +Amino acid transmembrane transporter activity 0.6844740021990661 1.6425837202255107 0.1004690913349453 1.0 0.7759374779621949 11 Q9Y619 1 +Small molecule sensor activity 0.7770631174105115 1.628156693140113 0.1034916648944559 1.0 0.7759374779621949 4 O75306 1 +Scavenger receptor activity 0.9569098184056636 1.625744645942221 0.1040039882254901 1.0 0.7759374779621949 3 Q14108,Q8WTV0 2 +Nucleobase containing compound transmembrane transporter activity 0.6281537890366907 1.6223721776615143 0.1047236826731474 1.0 0.7759374779621949 18 Q9BSK2,Q86VD7,Q9H2D1,P41440,Q8TB61 5 +Phosphatidylserine binding 0.6791576953316957 1.6174757549529757 0.1057756250316477 1.0 0.7759374779621949 11 Q14108,Q8WTV0 2 +Alcohol binding 0.6519663846972776 1.6159888140768175 0.1060967316914016 1.0 0.7759374779621949 15 O15118,P21796,P30536,P45880,Q14108 5 +Glycosphingolipid binding 0.9528341530683972 1.6102291572059524 0.1073478383217994 1.0 0.7759374779621949 3 Q9UM22 1 +Ganglioside binding 0.9528341530683972 1.6102291572059524 0.1073478383217994 1.0 0.7759374779621949 3 Q9UM22 1 +Galactosidase activity 0.9495229301323488 1.597618315919688 0.1101279476535341 1.0 0.7759374779621949 3 P06280,Q8IW92 2 +Proline rich region binding 0.7312218193259785 1.5820255187884045 0.1136437450075145 1.0 0.7759374779621949 5 Q9UQB8 1 +Ephrin receptor binding 0.6855819100571919 1.577422180352324 0.1146984151265098 1.0 0.7759374779621949 8 O00560,P46108 2 +Single stranded dna exodeoxyribonuclease activity 0.7296697316033284 1.5753825041146918 0.1151681803754938 1.0 0.7759374779621949 5 Q8IV08 1 +Glucosidase activity 0.729196319338181 1.5733557338044435 0.1156364707978216 1.0 0.7759374779621949 5 P04062 1 +Metalloexopeptidase activity 0.5771180437165196 1.5550413868575748 0.1199362128644674 1.0 0.8009201907151213 22 P53582,P55786,O75844,P09960,Q9NZ08,Q9UIQ6 6 +Nad binding 0.4628935892382549 1.5485407685625032 0.1214921540815985 1.0 0.8074287177958868 31 O75874,P40939,P48735,O75306,Q8IXJ6 5 +Cullin family protein binding 0.6800230656629567 1.534744317447716 0.1248466452447023 1.0 0.8157716020135457 7 Q8IWE4,Q92564,Q9BTE7 3 +Phospholipid transporter activity 0.678826068724129 1.5294120043773851 0.1261623383642591 1.0 0.8157716020135457 7 Q00169 1 +Peptide binding 0.5245510974220301 1.5288662857110284 0.1262975956765655 1.0 0.8157716020135457 73 P24390,P55786,P42892,O43731,Q9UHV9,Q6UWU4,Q9H7Z7,Q6P179,Q03518,Q9BYT8,O14773,Q8WTV0,Q9NQX7,Q9UIQ6,Q9Y584,Q9NQP4,Q9NZ08,P10321,P30414,P01889,Q15392,Q92973 22 +Metalloendopeptidase activity 0.6344008573870573 1.526116992555117 0.1269807309084281 1.0 0.8157716020135457 15 Q10713,P42892,P22695,Q99797,O75844,O43847 6 +Sterol transporter activity 0.6736620502373242 1.5235610665127024 0.1276183951356886 1.0 0.8157716020135457 8 P30536,O15118 2 +Protein phosphatase activator activity 0.6732959167719873 1.521903476401128 0.1280332679906068 1.0 0.8157716020135457 8 Q15257,O94766,P0DP25,Q5MIZ7 4 +Nucleoside diphosphatase activity 0.7487932531451177 1.509429120274579 0.1311891560129658 1.0 0.8208186382973406 4 Q86VD7,Q96DE0 2 +Anion channel activity 0.6376527379585194 1.5069620359936229 0.13182038853917 1.0 0.8210695949816463 14 P21796 1 +Protein transmembrane transporter activity 0.648301886075832 1.4974852448679514 0.1342670420748692 1.0 0.8271796082037085 12 Q99595,Q9NS69 2 +Copper ion binding 0.6631398888146232 1.494954006619898 0.1349264459991479 1.0 0.8271796082037085 9 O60888 1 +Pentosyltransferase activity 0.6281438143046435 1.4939701535325332 0.1351834204911748 1.0 0.8271796082037085 15 P43490,Q13126 2 +Thiolester hydrolase activity 0.6257836410118858 1.481827347139946 0.1383862405402802 1.0 0.8401422218116679 15 P50897,Q9UMR5,Q9NUJ1 3 +Dicarboxylic acid transmembrane transporter activity 0.6617858036778332 1.4697032608750795 0.1416421391873714 1.0 0.8516923434253634 8 Q9BQT8,Q9UBX3,Q02978,O75746,P41440 5 +Epidermal growth factor receptor binding 0.6660959363349516 1.4583961074531282 0.1447313929820497 1.0 0.8597430189720101 6 Q92600,O00291,Q13596,O60749 4 +Growth factor receptor binding 0.612298500555398 1.449481171390642 0.1472032547821493 1.0 0.8597430189720101 16 P05067,O00560,Q92542 3 +Proteasome binding 0.6427431774520992 1.444277461500467 0.1486609430672838 1.0 0.8597430189720101 11 P54725,P54727,P46379,O95456,Q92530 5 +Peptidase activator activity 0.6420190869999867 1.4408141567141153 0.1496371929047326 1.0 0.8597430189720101 11 Q9UL46,P05067,P63244,P53634,Q9BXK5 5 +Macromolecule transmembrane transporter activity 0.6303347692073271 1.438398683104262 0.1503209660779725 1.0 0.8597430189720101 13 Q99595,Q9NS69 2 +Inorganic anion transmembrane transporter activity 0.5367484302832785 1.4380896958181797 0.15040860591087 1.0 0.8597430189720101 24 P21796,O43681,P45880,Q9Y277,Q9UBX3,P33527,Q15043 7 +Sh2 domain binding 0.6542117888274288 1.4352636312790958 0.151211987241933 1.0 0.8607928290124797 8 Q8NEM2,P46108,Q07666 3 +Glycosyltransferase activity 0.4632953840720454 1.4117285363595606 0.158029907589897 1.0 0.8752821250510097 48 Q6ZXV5,P43490,P06865,P04062,Q8N6G5,Q13126 6 +Exogenous protein binding 0.6119667092471208 1.4105685305052529 0.1583718761974735 1.0 0.8752821250510097 15 Q14108,O15118,Q8WTV0 3 +Phosphatase inhibitor activity 0.6505451740209001 1.4029076528003654 0.160644378526563 1.0 0.8752821250510097 7 Q01105,O43768,Q9Y570 3 +Phosphatidylcholine transporter activity 0.8968531147831209 1.396618205478827 0.1625284126727386 1.0 0.8752821250510097 3 Q00169 1 +Retromer complex binding 0.7200418346734336 1.3881097018078652 0.1651036427599428 1.0 0.8752821250510097 4 P20645 1 +Rna strand annealing activity 0.7191030812371519 1.384142221594514 0.166314910883754 1.0 0.8752821250510097 4 Q15056,P51114 2 +Xenobiotic transmembrane transporter activity 0.6818479038888162 1.3695683760768411 0.1708216769448562 1.0 0.8820494768639604 5 P33527,P08183 2 +Abc type transporter activity 0.633882735381134 1.3595899679556591 0.1739597145441536 1.0 0.8949260870438124 9 Q9HD20,P33527,Q9NUT2,P08183 4 +5 3 exonuclease activity 0.6342586013913656 1.3442401612624837 0.1788707385856338 1.0 0.9096093276304964 8 Q8IV08 1 +Phosphatidylinositol 3 5 bisphosphate binding 0.6389085835949262 1.3381441733541477 0.1808494434152323 1.0 0.9096093276304964 6 O00291,Q92538,Q9Y5X3 3 +Hormone binding 0.6360229713623531 1.3376181036162438 0.1810209599151864 1.0 0.9096093276304964 7 P30536,P42892 2 +High density lipoprotein particle binding 0.8780742009532349 1.324937315533429 0.1851919429612301 1.0 0.9096093276304964 3 Q9BQE5 1 +Protein lipid complex binding 0.8780742009532349 1.324937315533429 0.1851919429612301 1.0 0.9096093276304964 3 Q9BQE5 1 +Trna guanine methyltransferase activity 0.6331164839929011 1.3245297470058155 0.1853271704243559 1.0 0.9096093276304964 7 Q9UET6,O75648 2 +Endopeptidase activity 0.4893984567274667 1.3052342173028362 0.1918131060893042 1.0 0.9109303536977148 69 P28070,Q99797,P42892,P22695,P49721,O43847,P28074,Q6P179,P51784,Q9BXS4,O14773,Q92542,Q9UDY8,Q4J6C6,P28072,O75844,Q9NZ08,P60900,Q10713,P20618 20 +Snap receptor activity 0.6087162513715095 1.3043546838576672 0.1921126784465348 1.0 0.9109303536977148 12 O60499,Q9P2W9,O15498,Q13190 4 +Phosphatase activator activity 0.6219791061693841 1.3042698540797193 0.1921415899637786 1.0 0.9109303536977148 9 Q15257,O94766,P0DP25,Q5MIZ7 4 +C4 dicarboxylate transmembrane transporter activity 0.6303093154218804 1.299978477251093 0.1936083459207731 1.0 0.9109303536977148 6 Q9UBX3,Q02978,O75746 3 +Histone acetyltransferase binding 0.6275010105399209 1.299225425151144 0.1938665784520679 1.0 0.9109303536977148 7 Q15650,Q8IXJ6,P42224 3 +Modified amino acid binding 0.5424109619674267 1.288543074781119 0.1975569845583393 1.0 0.9118473577365253 21 Q9H7Z7,P00374,Q14108,P04818,Q06481,P41440,Q8WTV0 7 +Phosphatidylglycerol binding 0.8669661879856226 1.2825873710335869 0.199636676991703 1.0 0.9118473577365253 3 Q00169 1 +Acetylglucosaminyltransferase activity 0.6213160489568939 1.271332229315369 0.2036104812055814 1.0 0.9118473577365253 7 P37287,Q93063,O43505,P06865 4 +Quinone binding 0.6171782043875798 1.2526601134883202 0.2103294276740377 1.0 0.9247316939861864 7 Q8N0U8 1 +Mannosidase activity 0.6875458217059923 1.250700197682407 0.2110438783251411 1.0 0.9247316939861864 4 O00462 1 +Gated channel activity 0.57210068863977 1.2368386010587968 0.2161470081899619 1.0 0.9313293955106344 16 P21796 1 +Trna methyltransferase activity 0.6091655221423401 1.2293234580780226 0.2189505554908102 1.0 0.9313293955106344 8 Q9UET6,O75648 2 +Phosphotyrosine residue binding 0.6114464853673667 1.2267839775357017 0.2199037944774449 1.0 0.9313293955106344 7 P07737,P46108,P46109 3 +Ubiquitin conjugating enzyme binding 0.6081483816227253 1.224658707045786 0.2207038384565685 1.0 0.9317861143348743 8 Q8IWE4,Q92564 2 +Peptidase regulator activity 0.4222908435957123 1.2195868583805909 0.2226215307022911 1.0 0.9339976525876178 31 P04080,Q9UL46,P05067,P63244,P53634,Q9BXK5,Q06481,Q92530 8 +Growth factor binding 0.5841364392139595 1.208051567468504 0.22702742757573 1.0 0.9392192761534388 13 Q15375,O00560,O14786,Q92896,O43847 5 +Lysophospholipase activity 0.6434703630864553 1.2034653158182391 0.228796305477646 1.0 0.9392192761534388 5 Q8NCC3 1 +Oxidoreduction driven active transmembrane transporter activity 0.4329753693982673 1.202956730600883 0.2289930651518648 1.0 0.9392192761534388 30 O75380,P00403,O43676,Q9UDW1,O95168,O95182,O75306 7 +Iron ion binding 0.5155454489415451 1.180499472395692 0.2378016201707267 1.0 0.9601246466663672 22 O15460,Q6UW02,Q9UMS0,P02792,Q16850,Q9NVH6,Q32P28 7 +Peptidase activator activity involved in apoptotic process 0.8384118190212386 1.1740556578093635 0.2403727329013789 1.0 0.9601246466663672 3 Q9BXK5,P63244 2 +Phospholipid binding 0.5092765802031074 1.171229604017002 0.2415064987725139 1.0 0.9601246466663672 90 Q8NCC3,P21796,Q9UM22,Q00169,P45880,P50897,Q14108,O00560,O14773,Q8WTV0,Q9H0F7,P07602,P04083,Q9BWH2 14 +L amino acid transmembrane transporter activity 0.5924241866268765 1.1665712407385618 0.2433835631188656 1.0 0.9601246466663672 9 P30825,Q9Y619,O75746 3 +Er retention sequence binding 0.9959999999999998 1.154598292779908 0.2482549661260811 1.0 0.9626328373605644 2 P24390 1 +Sterol transfer activity 0.8324367031411126 1.1514315687549346 0.2495547327036731 1.0 0.9626328373605644 3 P30536 1 +Heparin binding 0.5759361528929507 1.143467483842075 0.2528445476789853 1.0 0.9626328373605644 12 O14786,P05067,Q06481,O14737 4 +Actin monomer binding 0.6558949617121896 1.117134945899363 0.2639366306372406 1.0 0.9731853681091176 4 P07737 1 +Hexosyltransferase activity 0.4043486495509455 1.1133581442225555 0.2655546437102394 1.0 0.9731853681091176 36 Q6ZXV5,Q93063,P06865,P37287,P04062,Q8N6G5,O43505,Q13126 8 +Protein transporter activity 0.5540176178676977 1.1096021499036486 0.2671705044425239 1.0 0.9731853681091176 15 Q99595,Q9NS69,Q9Y584 3 +Neutral amino acid transmembrane transporter activity 0.6199568832768758 1.1017622207952404 0.2705650587109267 1.0 0.9731853681091176 5 P08195,Q96NB2,Q15758,Q9H9B4 4 +Signaling receptor regulator activity 0.5261842043248787 1.0993529288291326 0.2716141539598684 1.0 0.9731853681091176 19 P05067,P43490 2 +Dna directed dna polymerase activity 0.580716928270499 1.098819032088978 0.2718470089973861 1.0 0.9731853681091176 8 P56282,Q9NRG0 2 +L ascorbic acid binding 0.583114214213043 1.098818326902223 0.2718473166496311 1.0 0.9731853681091176 7 P13674,O15460,Q32P28 3 +Mhc protein complex binding 0.5768205322846719 1.080956670033262 0.2797163883850821 1.0 0.9861067600682212 8 P08238,P07900,Q9NUQ9 3 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9741538461538436 1.078993888763519 0.2805904519777957 1.0 0.9866838931573628 2 P30519 1 +Phosphatidylinositol 3 kinase binding 0.8099751713789362 1.0667646090249794 0.2860781436261317 1.0 0.9896368091324232 3 P0DP25 1 +Amyloid beta binding 0.5590306765040103 1.060469514859841 0.2889310517346684 1.0 0.9896368091324232 12 Q9UHV9,Q9NQP4,Q9NQX7,Q8WTV0 4 +Folic acid binding 0.8082486919052031 1.060286019557756 0.2890144975254127 1.0 0.9896368091324232 3 P41440,P00374 2 +Sulfuric ester hydrolase activity 0.8072453027095636 1.0565229835660523 0.290729346045127 1.0 0.9896368091324232 3 P15586 1 +Phosphoric diester hydrolase activity 0.5650636546109209 1.03908809316957 0.298763768016407 1.0 0.9896368091324232 9 P09601 1 +Thiol oxidase activity 0.7989674532227133 1.025542390006892 0.3051073345669208 1.0 0.9896368091324232 3 P07237 1 +Electron transfer activity 0.4221331322471575 1.0246750220519074 0.3055165525607588 1.0 0.9896368091324232 51 P14406,O75380,P00403,O43676,Q9UDW1,O15460,O95168,O95182,O75306 9 +Peptidyl proline 4 dioxygenase activity 0.7987072945521716 1.0245706569166582 0.3055658158090315 1.0 0.9896368091324232 3 O15460,P07237 2 +Procollagen proline 4 dioxygenase activity 0.7987072945521716 1.0245706569166582 0.3055658158090315 1.0 0.9896368091324232 3 O15460,P07237 2 +Lipopolysaccharide binding 0.5654923224278873 1.0193625971460265 0.30803085618165 1.0 0.9896368091324232 7 Q8WTV0 1 +Phospholipase d activity 0.955999999999998 1.0167206258714925 0.3092863508211365 1.0 0.9896368091324232 2 P09601 1 +Chemoattractant activity 0.6302801012531052 1.0097517333599335 0.3126142500475475 1.0 0.9896368091324232 4 P14174,P26583 2 +Nedd8 specific protease activity 0.7943896089189197 1.0084616539957547 0.3132328875648222 1.0 0.9896368091324232 3 Q96FW1 1 +Transferase activity transferring alkyl or aryl other than methyl groups 0.4864832133227409 1.0025658743045025 0.3160703679975036 1.0 0.9896368091324232 22 P31153,O15217,P49366,O00116,Q96EY8,P49356,P19623,P14324,Q9NR45,P37268 10 +Acetylgalactosaminyltransferase activity 0.7912259282722719 0.996680741890381 0.3189195003435792 1.0 0.9896368091324232 3 Q8N6G5 1 +Galactoside binding 0.94923076923077 0.9936520581217134 0.3203922905292331 1.0 0.9896368091324232 2 P06280 1 +Beta galactosidase activity 0.9492307692307648 0.993652058121697 0.3203922905292411 1.0 0.9896368091324232 2 Q8IW92 1 +5 3 exodeoxyribonuclease activity 0.9461538461538468 0.9831963433300754 0.325510814144887 1.0 0.9896368091324232 2 Q8IV08 1 +Glucuronosyltransferase activity 0.7860880270852585 0.9775911595845572 0.3282765714328146 1.0 0.9896368091324232 3 Q93063,O43505 2 +Dipeptidyl peptidase activity 0.7847335578635917 0.972567919901162 0.3307680930672603 1.0 0.9896368091324232 3 P42785 1 +Abc type xenobiotic transporter activity 0.7830234466839403 0.9662314107116544 0.333928398588222 1.0 0.9896368091324232 3 P33527 1 +Efflux transmembrane transporter activity 0.7830234466839403 0.9662314107116544 0.333928398588222 1.0 0.9896368091324232 3 P33527 1 +Solute anion antiporter activity 0.5547585043451366 0.9643073556800916 0.3348918541636148 1.0 0.9896368091324232 6 Q02978,P41440 2 +Exodeoxyribonuclease activity 0.5487429479330088 0.9633039049369536 0.3353950342244316 1.0 0.9896368091324232 9 Q8IV08 1 +Nadplus binding 0.5529149642337557 0.9628308147390814 0.3356324339533683 1.0 0.9896368091324232 7 Q8IXJ6,P40939 2 +O methyltransferase activity 0.552615165021995 0.9614858158523976 0.3363079539733253 1.0 0.9896368091324232 7 O60725 1 +Glutamate receptor binding 0.553661498906738 0.9594601751433928 0.3373269730719581 1.0 0.9896368091324232 6 P0DP25,P41440 2 +Nitric oxide synthase regulator activity 0.781163434903049 0.9593468119592184 0.3373840601507176 1.0 0.9896368091324232 3 P08238,P0DP25 2 +Oligopeptide binding 0.6146984032991967 0.944969319981046 0.3446745393545878 1.0 1.0 4 Q9H7Z7 1 +Protein methyltransferase activity 0.4109977560229081 0.9430683599231998 0.3456459382346664 1.0 1.0 29 Q9BV86 1 +Solute cation symporter activity 0.5464943471995592 0.9423685633909792 0.346003976268546 1.0 1.0 8 O00400 1 +Scaffold protein binding 0.4798677812803769 0.9158485120079812 0.3597463551153699 1.0 1.0 21 P07602,Q9UQB8 2 +Mannose binding 0.5404827826860529 0.915042522314159 0.3601693073918537 1.0 1.0 8 O75503 1 +Protein phosphorylated amino acid binding 0.5278450962817699 0.9080280524063186 0.3638634007552537 1.0 1.0 12 P07737,P46108,Q92541,P46109 4 +Dynactin binding 0.5398118553062128 0.9041837276177938 0.3658979871960794 1.0 1.0 7 Q8TD16,Q9Y5X3 2 +Protein self association 0.5182186714232198 0.9000088954372486 0.368115516823182 1.0 1.0 14 Q9Y282,P46108 2 +Atpase coupled inorganic anion transmembrane transporter activity 0.6002056349049107 0.885222225202321 0.3760367875768544 1.0 1.0 4 P33527 1 +Sodium ion transmembrane transporter activity 0.5364304280651327 0.88359148308294 0.3769167782947269 1.0 1.0 6 Q9Y6M7,Q6P4Q7,P05023,P08195 4 +Signaling receptor complex adaptor activity 0.5337681842020172 0.8719222671048705 0.3832507852135047 1.0 1.0 6 P46108 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.5227719152143975 0.8676640151396409 0.3855782908422043 1.0 1.0 11 Q13510 1 +2 oxoglutarate dependent dioxygenase activity 0.5116960088814926 0.8671095704271689 0.3858819773104871 1.0 1.0 14 Q9NVH6,O15460,Q32P28 3 +Ubiquitin specific protease binding 0.527729016626394 0.8663385716251624 0.3863045198611226 1.0 1.0 9 P46379 1 +Mhc class ii protein complex binding 0.5275041585426105 0.8494103535551206 0.3956529939927922 1.0 1.0 7 P08238,P07900 2 +Acetyl coa c acetyltransferase activity 0.5608825973066307 0.849112460711638 0.395818717372935 1.0 1.0 5 P40939 1 +C acetyltransferase activity 0.5283283395006425 0.8481303438238914 0.3963653843639543 1.0 1.0 6 P40939 1 +Carbohydrate derivative transmembrane transporter activity 0.5116821812958617 0.8469864591765862 0.397002668968109 1.0 1.0 13 Q86VD7,Q8TB61,P41440 3 +Signaling adaptor activity 0.4982892274912889 0.845962499994624 0.3975736643124565 1.0 1.0 16 P63244,Q07666,P46108,P46109 4 +Folic acid transmembrane transporter activity 0.904923076923067 0.8452255447879027 0.3979849224659646 1.0 1.0 2 Q9H2D1 1 +Primary active transmembrane transporter activity 0.4045848953552298 0.8207364049224372 0.4117964295789704 1.0 1.0 55 Q9HD20,O75380,P00403,O43676,Q9UDW1,Q9NUT2,P33527,O95168,O95182,Q9Y6M9,O75306,P08183 12 +Ferric iron binding 0.8926153846153788 0.8049522723927034 0.4208472221519204 1.0 1.0 2 P02792 1 +Protein disulfide reductase nad p activity 0.5459956879855474 0.7867387543614132 0.4314348126382692 1.0 1.0 5 Q6DKJ4 1 +Protein serine threonine kinase activator activity 0.5093779099118376 0.7825381563164643 0.4338983703237429 1.0 1.0 9 P14635,P0DP25,Q9Y376,Q13043 4 +Voltage gated chloride channel activity 0.5715836481586032 0.7691624945444784 0.4417968523002227 1.0 1.0 4 P51797 1 +Cytokine binding 0.5089082002084501 0.7638737661325998 0.4449424722269612 1.0 1.0 6 O14786,Q92905,P06756 3 +Nucleoside kinase activity 0.5676711363342621 0.7535433171805942 0.4511234914332012 1.0 1.0 4 P27707 1 +Oxidoreductase activity acting on a sulfur group of donors 0.4193333143793721 0.7339946658679252 0.4629519890709592 1.0 1.0 25 Q8NBM8,P07237,Q9UHG3,O95881 4 +Dopamine receptor binding 0.5621111788636538 0.7314659094397743 0.4644946199753277 1.0 1.0 4 P50570 1 +Udp glycosyltransferase activity 0.4598266311315399 0.7259120138158344 0.4678927110961894 1.0 1.0 19 O60568,Q93063,P06865,P37287,Q8N6G5,P26572,O94766,Q7Z4H8,Q10472,O43505 10 +Monosaccharide binding 0.3814404262586582 0.7211227677826424 0.470833984091491 1.0 1.0 29 O75503,O00462,O15460,Q32P28 4 +Nadh dehydrogenase activity 0.4319874854844094 0.7158016356446654 0.4741138423169841 1.0 1.0 23 O75380,O43676,O95182,O95168,O75306 5 +Guanyl nucleotide exchange factor activity 0.3569771087029011 0.7153276432228658 0.4744066112285154 1.0 1.0 36 P80303,A4D1U4,Q9UI10,P49770,Q02818 5 +Zinc ion transmembrane transporter activity 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +Translation activator activity 0.5572660098522088 0.7123467684777466 0.4762500698330638 1.0 1.0 4 P11940,Q6PKG0,Q7Z478 3 +Prenyltransferase activity 0.4953524447264823 0.7058438993633022 0.4802852185459321 1.0 1.0 6 P49356,P37268 2 +Dioxygenase activity 0.4711779116753774 0.7053039999823077 0.4806210717368646 1.0 1.0 16 Q9NVH6,O15460,Q32P28 3 +Alpha glucosidase activity 0.7093809273041648 0.7014804795286378 0.4830032125890175 1.0 1.0 3 P10253 1 +Peptide n acetyltransferase activity 0.4813237121667638 0.6990534338513392 0.4845186382502402 1.0 1.0 13 Q86UY6,Q14CX7 2 +Peptide transmembrane transporter activity 0.7081519267506831 0.6972356674980363 0.4856553209852785 1.0 1.0 3 P33527 1 +Antiporter activity 0.4837361543055349 0.6963733558437125 0.4861950445659933 1.0 1.0 12 P41440,P51790,Q9UBX3,P51797 4 +Endopeptidase regulator activity 0.4033184181634041 0.6831976893105827 0.494481932560999 1.0 1.0 26 P04080,Q92530,Q06481,P05067 4 +Secondary active transmembrane transporter activity 0.4192456213258611 0.682992080480419 0.4946118468368554 1.0 1.0 24 P51790,Q8NE86,O00400,Q9UBX3,P51797,P41440,Q15043 7 +Amide binding 0.4702415805305552 0.6758533815527411 0.4991337385060812 1.0 1.0 105 P21796,Q9UM22,P00374,P24390,P42892,P55786,P45880,O43731,Q9UHV9,P07602,Q6UWU4,Q9H7Z7,Q6P179,Q03518,Q9BYT8,O14773,P41440,Q8WTV0,Q9NQX7,Q9UIQ6,Q9Y584,Q00169,Q9NZ08,Q9Y680,P10321,P30414,P40939,P01889,Q15392,Q92973 30 +Axon guidance receptor activity 0.8501538461538407 0.6701798694299983 0.5027431349652385 1.0 1.0 2 Q15375 1 +O acyltransferase activity 0.4641408249423369 0.6693513166354141 0.5032713989948006 1.0 1.0 16 P23786,Q9HCL2,Q8NCC3,Q96N66 4 +Ubiquitin protein transferase activator activity 0.5430299067761762 0.6568803986926194 0.5112578227173372 1.0 1.0 4 Q12834,Q9HC52 2 +Leucine binding 0.8436923076922985 0.6503294548187709 0.5154794347996305 1.0 1.0 2 P00367 1 +L ornithine transmembrane transporter activity 0.8421538461538305 0.6456319033001449 0.5185177709700621 1.0 1.0 2 Q9Y619 1 +Peptidase activity 0.4843325376073706 0.6423996908919203 0.5206137003602629 1.0 1.0 117 P28070,P42892,P55786,Q99797,Q9HB40,Q7Z2K6,P22695,P09960,P49721,O43847,Q6P179,P28074,P53582,P10619,P51784,Q9BYT8,Q9BXS4,P42785,O14773,Q92542,Q9UIQ6,Q9UDY8,Q9BT78,Q96FW1,Q4J6C6,Q9H3G5,P28072,O75844,Q9NZ08,P60900,Q96KP4,Q10713,O00303,Q9Y4P1,Q92820,P20618 36 +Nitric oxide synthase binding 0.8378461538461419 0.6325391746372966 0.5270346185602315 1.0 1.0 2 P0DP25 1 +Cyclin dependent protein serine threonine kinase regulator activity 0.5081890679312049 0.6324493028131565 0.5270933261282245 1.0 1.0 5 P14635,P11802 2 +Polyubiquitin modification dependent protein binding 0.4593078848750298 0.6252914454223454 0.5317797934962325 1.0 1.0 15 Q9NRR5,P54725,Q96P47,P54727,P46379,Q8WXE1,Q15018 7 +Glycosaminoglycan binding 0.4460259259803812 0.6228352651015547 0.5333927815393622 1.0 1.0 18 P15586,P05067,Q06481,O14786,O14737 5 +Nucleocytoplasmic carrier activity 0.4443427084896372 0.6139738564535981 0.53923260325326 1.0 1.0 18 Q9C0E2,Q96P70,Q92973 3 +2 acylglycerol 3 phosphate o acyltransferase activity 0.6833160504443173 0.6130818172574074 0.5398222422601509 1.0 1.0 3 Q96N66 1 +Fatty acid derivative binding 0.4657056689969157 0.6122979479037046 0.5403406471362424 1.0 1.0 12 Q00169 1 +Acyl coa binding 0.4657056689969157 0.6122979479037046 0.5403406471362424 1.0 1.0 12 Q00169 1 +Purine nucleotide transmembrane transporter activity 0.460664193289575 0.600906427021223 0.5479023122530524 1.0 1.0 13 Q86VD7,Q8TB61,P41440 3 +Chloride ion binding 0.8264615384615372 0.5983818230711316 0.5495851914561827 1.0 1.0 2 P53634 1 +Galactosyltransferase activity 0.6775797173897027 0.5941245361166784 0.5524288212309185 1.0 1.0 3 O43505 1 +Lysophosphatidic acid phosphatase activity 0.8224615384615238 0.5865403139597019 0.5575124786007872 1.0 1.0 2 Q9NPH0 1 +Nadph binding 0.4655753893663609 0.5819496739291257 0.5606005798423006 1.0 1.0 7 P04035,P00374 2 +Symporter activity 0.4573719664538205 0.5579325421645944 0.5768904489291444 1.0 1.0 10 Q15043,Q15758,O00400,Q96ES6 4 +Nadp binding 0.427254943035895 0.5495474801402851 0.5826297900039632 1.0 1.0 19 O75874,P35270,P04035,P00374,P16435,Q14739 6 +Aspartic type peptidase activity 0.6622179685745536 0.5443527683517126 0.5861987412518268 1.0 1.0 3 Q92542 1 +Sphingosine n acyltransferase activity 0.8070769230769184 0.5418200496950676 0.5879424779333546 1.0 1.0 2 Q96G23 1 +Phosphatidylinositol phosphate phosphatase activity 0.4526592466713778 0.5299686537279712 0.5961336644516784 1.0 1.0 8 Q10713 1 +Camp dependent protein kinase regulator activity 0.6550630154136603 0.5217001427526191 0.6018791252727744 1.0 1.0 3 P10644 1 +Succinate transmembrane transporter activity 0.7993846153846 0.5199769540469301 0.6030796378743666 1.0 1.0 2 Q9UBX3 1 +Sulfate transmembrane transporter activity 0.7993846153846 0.5199769540469301 0.6030796378743666 1.0 1.0 2 Q9UBX3 1 +Transferrin receptor binding 0.5062893844291702 0.5196973720161197 0.6032745188610913 1.0 1.0 4 O60749,Q13596 2 +Ubiquitin like protein binding 0.3329280255924022 0.519515725566622 0.6034011496117244 1.0 1.0 36 Q96FW1,Q99816,P54725,Q9H1I8,Q8IWE4,Q92564,Q8IXJ6 7 +S100 protein binding 0.4494566799809918 0.5167371749312054 0.6053396415907359 1.0 1.0 8 Q9HB71,P31949 2 +C acyltransferase activity 0.4446844769744791 0.5033515988337651 0.6147170946961513 1.0 1.0 10 P35610,P40939 2 +Coreceptor activity 0.5005677746862621 0.4992594729779216 0.6175966017250702 1.0 1.0 4 O14786,P06756 2 +Kinase activator activity 0.4323280618321951 0.4952094049572031 0.620452312486798 1.0 1.0 15 Q9Y376,P14635,P0DP25,Q9UDY8,Q13043 5 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3667218248774198 0.4942106686824711 0.621157405945979 1.0 1.0 27 O75380,O43676,O95182,O95168,O75306 5 +Alkali metal ion binding 0.4439093324748632 0.4934910578954749 0.6216656566235672 1.0 1.0 7 P29218 1 +Translation repressor activity 0.4428843098374443 0.4919154873335908 0.6227790893391145 1.0 1.0 9 Q14011,P00374 2 +Thioredoxin disulfide reductase activity 0.7873846153846178 0.4866362424931494 0.6265161350893695 1.0 1.0 2 Q6DKJ4 1 +Ribosomal large subunit binding 0.4414459541523349 0.4859618027719855 0.6269942483095059 1.0 1.0 9 Q9NTK5 1 +Misfolded protein binding 0.4293889237068048 0.4814218041789257 0.6302167430098338 1.0 1.0 15 P46379 1 +Mhc class ib protein binding 0.7830769230769101 0.4748955814100802 0.6348614010185889 1.0 1.0 2 Q03518 1 +Lrr domain binding 0.639196638761891 0.4727758022823477 0.6363731394519068 1.0 1.0 3 Q6P1K2 1 +Oxidoreductase activity acting on nad p h 0.3291932250953019 0.471952136046977 0.6369609532097729 1.0 1.0 31 O75380,O43676,O95182,O95168,O75306 5 +Nuclear import signal receptor activity 0.4350082254532409 0.4675312890328952 0.6401198115713491 1.0 1.0 11 Q96P70,Q92973 2 +Lipase activity 0.4114266536346798 0.4670891115842857 0.6404361240236842 1.0 1.0 19 Q8NCC3,Q8NCG7,Q8NHP8,Q8IV08,P09601 5 +Acetyl coa c acyltransferase activity 0.4343264691962168 0.4555786190013342 0.6486930210317801 1.0 1.0 7 P40939 1 +Serine transmembrane transporter activity 0.6300400123114837 0.4454200839436781 0.6560162008266699 1.0 1.0 3 Q96NB2,Q15758 2 +Long chain fatty acid coa ligase activity 0.4285936360111529 0.4353406524424001 0.6633151811978073 1.0 1.0 6 Q9UKU0 1 +Arachidonate coa ligase activity 0.4285936360111529 0.4353406524424001 0.6633151811978073 1.0 1.0 6 Q9UKU0 1 +Catalytic activity acting on a glycoprotein 0.7664615384615422 0.4308014035756043 0.6666127789276071 1.0 1.0 2 O43505 1 +Transmembrane receptor protein tyrosine kinase activity 0.4803851933412842 0.429545645779696 0.6675261830864829 1.0 1.0 4 O14786,Q15375 2 +Transmembrane receptor protein kinase activity 0.4803851933412842 0.429545645779696 0.6675261830864829 1.0 1.0 4 O14786,Q15375 2 +Dystroglycan binding 0.4539574992300601 0.4270986544553561 0.66930747296108 1.0 1.0 5 P18206,O75122,Q9H9S5,Q7Z460 4 +Cadherin binding involved in cell cell adhesion 0.4235508616477046 0.4193961075278123 0.6749266683777604 1.0 1.0 11 P31949,Q9UQB8,P04083 3 +Metallocarboxypeptidase activity 0.4703653558864079 0.396446912342729 0.6917753640091062 1.0 1.0 4 O75976 1 +Sulfotransferase activity 0.7433846153845942 0.3729188303076821 0.7092088567727566 1.0 1.0 2 Q8NCH0 1 +Acylglycerol o acyltransferase activity 0.4128531957545847 0.3721351118081417 0.7097922551946405 1.0 1.0 8 Q8NCC3 1 +Rna polymerase ii general transcription initiation factor activity 0.4369315283348658 0.3681603321006823 0.7127536866116997 1.0 1.0 5 P29083 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.4084697517327338 0.3611227798560645 0.7180076648174258 1.0 1.0 6 Q9Y217,Q10713,Q8WUK0 3 +Ionotropic glutamate receptor binding 0.4554320339126507 0.3491871673310797 0.7269487995871995 1.0 1.0 4 P41440 1 +L aspartate transmembrane transporter activity 0.4538094168022102 0.3442100386839834 0.7306883332945047 1.0 1.0 4 O75746 1 +Acidic amino acid transmembrane transporter activity 0.4290113951339893 0.3418592439711487 0.7324568222920176 1.0 1.0 5 Q15758,Q9H936,Q9UPY5,O75746 4 +Endopeptidase activator activity 0.4287949597651277 0.3411510769844811 0.7329898512028139 1.0 1.0 5 Q9UL46 1 +Atpase coupled transmembrane transporter activity 0.3553080292612421 0.3375094746562218 0.7357328709889313 1.0 1.0 25 Q9HD20,P33527,P08183,Q9NUT2 4 +Anaphase promoting complex binding 0.4508251103364037 0.3351402453223505 0.737519295175777 1.0 1.0 4 P53350,Q12834 2 +Cis trans isomerase activity 0.354621529540304 0.3335823564404438 0.7386947338782177 1.0 1.0 25 Q8WUA2,P30414,Q15257,Q96AY3,O43708,O00170,O43447,Q9Y237,Q9NWM8,Q9Y680,Q9Y3C6 11 +Oxidoreductase activity acting on the ch nh group of donors 0.4013872742510149 0.3304854456744355 0.7410331881035037 1.0 1.0 11 Q6QHF9 1 +Insulin like growth factor binding 0.7249230769230732 0.3296588174413605 0.7416577746299549 1.0 1.0 2 P11717 1 +Protein tyrosine kinase binding 0.3794955474146193 0.3288335767075914 0.742281482583214 1.0 1.0 20 P07900,O00459,P63244,P46108,P12004,P46109,Q07666,P56537 8 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters 0.7236923076922903 0.3268761716038363 0.7437615442668499 1.0 1.0 2 Q96QE5 1 +Eukaryotic initiation factor 4e binding 0.447044334975359 0.3238088684853812 0.746082741570328 1.0 1.0 4 Q9UNK9,O00571,Q6PKG0 3 +Toxic substance binding 0.7209230769230813 0.3206626770824303 0.7484660341632106 1.0 1.0 2 P34913 1 +Plus end directed microtubule motor activity 0.3964857229063667 0.3106492368734054 0.7560672921310978 1.0 1.0 9 Q8NI77,Q9Y496,P52732 3 +Pre mirna binding 0.4179242377579302 0.3063378223612797 0.7593474444532062 1.0 1.0 5 O75569,Q9HAV4,Q9UPY3,Q9H2U1 4 +Fatty acid ligase activity 0.3932797351473825 0.3039504137508357 0.7611656689612065 1.0 1.0 7 Q9UKU0 1 +Dynein light chain binding 0.5713572235794301 0.2879600002428582 0.773377357515808 1.0 1.0 3 Q96EX3 1 +Structural constituent of eye lens 0.5709048303765453 0.2868795005030994 0.774204587277028 1.0 1.0 3 Q99797 1 +Udp xylosyltransferase activity 0.7052307692307673 0.2867181171129419 0.7743281643096429 1.0 1.0 2 Q7Z4H8 1 +Nuclear localization sequence binding 0.3849674525833285 0.2855179878672632 0.7752473253643766 1.0 1.0 15 Q6UWU4,P52292,Q92973 3 +Active transmembrane transporter activity 0.3720449985330169 0.2850175173884338 0.7756307213676326 1.0 1.0 77 Q9HD20,O75380,P00403,Q03518,O43676,Q9UDW1,Q9NUT2,Q9UBX3,O95182,P33527,O95168,Q9Y6M9,P41440,O75306,P08183 15 +Acyltransferase activity 0.3359778277938531 0.2779007002286257 0.7810885863616832 1.0 1.0 56 Q96G23,Q86UY6,Q8NCC3,O15498,Q14CX7,Q15102,P40939,Q96N66,P23786,P35610,Q9BXJ9,Q9HCL2 12 +Transmembrane transporter binding 0.3024151100911655 0.2767777904089246 0.7819507358869853 1.0 1.0 31 P30536,P21796 2 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.4055043761311704 0.2684688623579984 0.7883384396224795 1.0 1.0 5 P50336,Q15067 2 +Passive transmembrane transporter activity 0.3045000374548756 0.2632975404381988 0.7923212552759107 1.0 1.0 39 P45880,P21796 2 +Mdm2 mdm4 family protein binding 0.3787964101066846 0.260512332893032 0.7944686033813178 1.0 1.0 6 P61289,P62841 2 +Protein phosphatase 2a binding 0.3809999690467515 0.2545043453535856 0.7991059474863247 1.0 1.0 11 Q9Y570,Q86XL3,P78318,P42224 4 +Phosphatidylinositol 3 4 bisphosphate binding 0.6849230769230774 0.2460893579584236 0.8056130609300618 1.0 1.0 2 O00291 1 +N acyltransferase activity 0.3616768480934623 0.2448431478852128 0.8065778833166999 1.0 1.0 20 Q86UY6,Q14CX7,Q9BXJ9 3 +Sodium ion binding 0.6836923076923082 0.2437498680186994 0.8074245488371643 1.0 1.0 2 O00764 1 +Rna polymerase ii ctd heptapeptide repeat phosphatase activity 0.6778461538461459 0.2328320563983044 0.8158918194971709 1.0 1.0 2 Q05D32 1 +Acetyltransferase activity 0.3032708130485537 0.2299919694275146 0.8180980099356852 1.0 1.0 30 Q86UY6,Q14CX7,Q15102,P40939,Q9BXJ9 5 +C palmitoyltransferase activity 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 1.0 2 Q15118 1 +Transcription coactivator binding 0.3871265783800428 0.2164675206453741 0.8286233397437897 1.0 1.0 5 Q15648,P62829,O14578,P42224 4 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3690498299608532 0.2141551289461386 0.830426086194761 1.0 1.0 10 Q92538,Q9BWH2 2 +Oxidoreductase activity acting on ch oh group of donors 0.3330596523029433 0.211519417468929 0.8324819820134197 1.0 1.0 60 O75874,P48735,P40939,P51648,Q8N0U8,Q8N4Q0,Q06136 7 +Lipid binding 0.4580392628194583 0.211087533715194 0.8328189677227782 1.0 1.0 141 P21796,Q9UM22,O15118,P30536,P45880,P50897,Q9H0F7,P07602,A6NIH7,Q9BQE5,Q8NCC3,O14773,Q8WTV0,P61916,Q00169,Q14108,O00560,P04062,P04083,Q9BWH2,O15173 21 +Rage receptor binding 0.5360433861167226 0.2104682418267515 0.8333022358763682 1.0 1.0 3 P26583 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.3673047973719675 0.2070471739014991 0.8359730171777155 1.0 1.0 12 Q9NZ01,Q15392,Q9H7Z7,Q8N4Q0 4 +Gtp dependent protein binding 0.3616825250349073 0.2022364093324806 0.839731910622673 1.0 1.0 7 Q86YV9 1 +Translation repressor activity mrna regulatory element binding 0.3607281672136757 0.1994045077861378 0.8419463345880738 1.0 1.0 7 P00374 1 +Gtpase inhibitor activity 0.3806590699106843 0.1993833368637647 0.8419628940612136 1.0 1.0 5 Q13576,O94813,P46940,O00410 4 +Clathrin binding 0.354524357152976 0.1993779854189045 0.8419670798656946 1.0 1.0 19 Q10567,Q9Y6I3,Q9BXS5,P61966,Q5VW38 5 +N acetyltransferase activity 0.3589558042152262 0.1971525743454917 0.8437081423310651 1.0 1.0 17 Q86UY6,Q14CX7 2 +Phosphatidylinositol binding 0.3203734487885314 0.194494617278837 0.8457886100464505 1.0 1.0 54 P07737,Q8IYI6,Q9Y5X3,Q92538,Q00169,O00560,Q06481,Q8WTV0,Q9H0H5,Q9BWH2 10 +Extracellular matrix binding 0.3779593581822457 0.1924464755072234 0.8473924905091281 1.0 1.0 5 O94813 1 +Tpr domain binding 0.3944439262118151 0.1864810688714377 0.8520675233189505 1.0 1.0 4 P08238,P07900 2 +Cyclase activity 0.650153846153849 0.1855460726761296 0.8528007468052328 1.0 1.0 2 O00442 1 +G protein activity 0.3590188632867033 0.181555891093255 0.8559312672411661 1.0 1.0 14 Q9H0U4,Q15907,P61225 3 +Adenylyltransferase activity 0.3560419235511745 0.1804560727707773 0.8567945370645063 1.0 1.0 8 P51003,O43252,O95396,Q15046,Q9NQX3,Q8NFF5,Q9H6E5 7 +Dna polymerase activity 0.3590897874328241 0.1802155361855409 0.8569833620046821 1.0 1.0 11 P56282,Q9NRG0 2 +Ubiquitin like modifier activating enzyme activity 0.3557336621455026 0.179552572664831 0.8575038409624269 1.0 1.0 8 Q9GZZ9,Q13564,Q8TBC4,A0AVT1,O95396,P22314,Q9UBE0 7 +Transferase activity transferring sulphur containing groups 0.3547565796904406 0.1722961206128102 0.8632047340505962 1.0 1.0 9 Q8NCH0 1 +Protein kinase a regulatory subunit binding 0.352695092866751 0.1707350389696451 0.8644321102181247 1.0 1.0 8 O43823,Q9Y6D6 2 +L serine transmembrane transporter activity 0.629846153846158 0.1555620045211978 0.8763782762533048 1.0 1.0 2 Q15758 1 +Receptor tyrosine kinase binding 0.3464376611575164 0.1496693402999119 0.8810254985589749 1.0 1.0 17 O00459,P63244,P46108,P12004,P46109,P56537 6 +Laminin binding 0.3765394088669838 0.1491815905546462 0.8814103460428584 1.0 1.0 4 P17931,P08865,O94813 3 +Phosphoprotein binding 0.3142816951885195 0.1466678276765904 0.8833942137270012 1.0 1.0 26 P11717,P07737,O15344,P06400,P46108,P46109,Q92541 7 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.3580943507149665 0.1450402629089016 0.8846790826763313 1.0 1.0 5 P11802,P06493 2 +Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor 0.3411812181421069 0.1448020236926759 0.8848671843916087 1.0 1.0 7 Q6DKJ4 1 +Type i transforming growth factor beta receptor binding 0.6184615384615434 0.1404808268116838 0.888280100251273 1.0 1.0 2 Q9UNH7 1 +Collagen binding 0.3420077634338616 0.1358907703299607 0.8919076320007537 1.0 1.0 9 O75718,Q32P28 2 +Fibronectin binding 0.4912588251280684 0.1331563680200601 0.8940697167637102 1.0 1.0 3 Q53GQ0 1 +Ubiquitin binding 0.3002979409540568 0.1327973691838566 0.8943536350194985 1.0 1.0 28 Q96FW1,Q99816,P54725,Q9H1I8,Q8IXJ6 5 +Microtubule minus end binding 0.3351002985758648 0.1291880102382652 0.8972088831513327 1.0 1.0 7 Q9H6D7 1 +Ligase activity forming phosphoric ester bonds 0.3639162561576281 0.1259290001250628 0.8997881266255798 1.0 1.0 4 O00442,Q9Y3I0,P49916 3 +Phosphatidylethanolamine binding 0.3299964818348939 0.1237604484089814 0.9015049485866375 1.0 1.0 6 P50995,P30086 2 +1 acylglycerophosphocholine o acyltransferase activity 0.6003076923076878 0.1189491919664847 0.9053156088268663 1.0 1.0 2 Q8NF37 1 +Solute sodium symporter activity 0.599692307692314 0.118272496676917 0.905851748893176 1.0 1.0 2 Q9Y6M7 1 +Cation chloride symporter activity 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 1.0 2 Q9BXP2 1 +Potassium chloride symporter activity 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 1.0 2 Q9BXP2 1 +Metal dependent deubiquitinase activity 0.3292105791736226 0.114709006422703 0.908675774962397 1.0 1.0 7 O00303,O15372 2 +Nucleoside triphosphatase regulator activity 0.3474747351503853 0.1145858342872022 0.9087734083463732 1.0 1.0 78 P80303,Q15437,P52565,P31150,Q8N6T3,P55010,P49770,Q92538,Q02818,Q9H0H5,Q96P47,O95373,O14786,Q8TC07,A4D1U4,Q9UI10,Q96EY1,Q66K14,Q86VI3 19 +C3hc4 type ring finger domain binding 0.4742997845490967 0.1100880538081764 0.9123395422498756 1.0 1.0 3 P11142,P31689 2 +Snare binding 0.2832351995492357 0.1083560692863395 0.9137132475230516 1.0 1.0 30 Q6ZWJ1,O60499,Q15833,O95486,Q9UNK0,P51809,Q13190 7 +Mismatch repair complex binding 0.3525246305418597 0.1071093516383943 0.9147022283151252 1.0 1.0 4 P52701,P43246,P12004 3 +Mutlalpha complex binding 0.3525246305418597 0.1071093516383943 0.9147022283151252 1.0 1.0 4 P52701,P43246,P12004 3 +Potassium ion binding 0.320192051014222 0.1012459599673121 0.919355213356694 1.0 1.0 6 O00764,P35610 2 +Molecular carrier activity 0.2872970839010708 0.0956369610858026 0.9238089090292596 1.0 1.0 29 Q9C0E2 1 +Nucleoside diphosphate kinase activity 0.3239360958579335 0.0790575654858754 0.936986835659556 1.0 1.0 5 P27144 1 +Mitogen activated protein kinase p38 binding 0.4414394611218733 0.0746182068395953 0.9405184875447744 1.0 1.0 3 Q16539 1 +Long chain fatty acyl coa binding 0.4376731301939104 0.0712851997969481 0.9431707741126834 1.0 1.0 3 O00154,P07108 2 +Ubiquitin like protein conjugating enzyme activity 0.3120908951578186 0.0691907203047906 0.9448378095305768 1.0 1.0 8 P61088,P49427 2 +Myosin binding 0.3163926586939278 0.0663977781134567 0.9470611391098313 1.0 1.0 10 P11233,Q15907,Q9Y6D6,Q86VI3 4 +Cobalamin binding 0.3214981048022556 0.0659712207583309 0.9474007380325824 1.0 1.0 4 Q96EY8,Q99707 2 +Neurotrophin receptor binding 0.5350769230769282 0.0649995075064509 0.9481743923800208 1.0 1.0 2 P19174 1 +Neurotrophin trk receptor binding 0.5350769230769282 0.0649995075064509 0.9481743923800208 1.0 1.0 2 P19174 1 +P type potassium transmembrane transporter activity 0.5258461538461653 0.0599574131059617 0.9521895530524044 1.0 1.0 2 P05023 1 +Phosphatidylinositol phosphate binding 0.2736330390904895 0.0557285896143867 0.9555580236687572 1.0 1.0 30 P07737,Q92538,O00560,Q9H0H5,Q9BWH2 5 +Pdz domain binding 0.317867194892501 0.0537733811077438 0.9571157176245236 1.0 1.0 15 P51790,Q9UQB8,Q9Y624,Q15067 4 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.2958594399033278 0.0530482683924708 0.957693449212137 1.0 1.0 6 Q9BXK5 1 +Lipase binding 0.5107692307692389 0.0528729038136183 0.957833173813035 1.0 1.0 2 Q96CS3 1 +Metallochaperone activity 0.506153846153856 0.05096932491981 0.959349963932466 1.0 1.0 2 O75880 1 +Copper chaperone activity 0.506153846153856 0.05096932491981 0.959349963932466 1.0 1.0 2 O75880 1 +Vascular endothelial growth factor receptor binding 0.5043076923077051 0.0502406927300014 0.9599305843723828 1.0 1.0 2 Q9Y5K6 1 +Glutathione disulfide oxidoreductase activity 0.4990769230769285 0.0482746368207742 0.9614973678654342 1.0 1.0 2 P78417 1 +Active ion transmembrane transporter activity 0.2786754883785339 0.0419483738620714 0.9665398535463976 1.0 1.0 44 P31930,P51790,Q9HD20,P00403,O00400,Q9UDW1,P51797,P33527,P41440,Q15043 10 +Ribose phosphate diphosphokinase activity 0.476307692307704 0.0412636526899216 0.967085709328288 1.0 1.0 2 Q14558 1 +Diphosphotransferase activity 0.476307692307704 0.0412636526899216 0.967085709328288 1.0 1.0 2 Q14558 1 +Dna translocase activity 0.4680000000000013 0.0392606408957247 0.9686825864213892 1.0 1.0 2 Q2NKX8 1 +Ion transmembrane transporter activity 0.3828326591668362 0.0389714296067665 0.9689131671736836 1.0 1.0 109 Q70HW3,P21796,P45880,O75964,Q9H2D1,P33527,O43772,P24539,Q8TAD4,Q9Y277,P41440,Q9Y619,Q9HD20,P00403,Q9UDW1,O00400,Q9UBX3,Q9Y487,Q93050,O43681,Q86VD7,Q9HC07,Q8TB61 23 +Kinesin binding 0.3001407172392343 0.0383869575963985 0.9693791596489256 1.0 1.0 9 O14657 1 +Notch binding 0.4618461538461522 0.0379437265572364 0.9697325493827408 1.0 1.0 2 Q13573 1 +S methyltransferase activity 0.4600000000000038 0.0375746157092534 0.9700268473547008 1.0 1.0 2 Q99707 1 +Mismatched dna binding 0.2850985221674781 0.0347741719893747 0.9722598159383548 1.0 1.0 4 P52701,P43246,P12004 3 +Dna insertion or deletion binding 0.2850985221674781 0.0347741719893747 0.9722598159383548 1.0 1.0 4 P52701,P43246,P12004 3 +Chemokine binding 0.3764235149276755 0.0347562927143999 0.9722740729175668 1.0 1.0 3 P09429,P06756 2 +Map kinase phosphatase activity 0.4356923076923073 0.0336932165144476 0.9731217883402814 1.0 1.0 2 Q99956 1 +Nedd8 transferase activity 0.4350769230769232 0.0336159176192913 0.9731834290173556 1.0 1.0 2 Q8TBC4 1 +Single stranded dna endodeoxyribonuclease activity 0.3693444136657483 0.0323136734855111 0.9742219050350512 1.0 1.0 3 P18887,P49959 2 +Cxcr chemokine receptor binding 0.3873846153846129 0.029840131265473 0.9761945528843692 1.0 1.0 2 Q96J02 1 +Phospholipid scramblase activity 0.3852307692307621 0.02974751534143 0.9762684169094348 1.0 1.0 2 Q7Z3C6 1 +C x3 c chemokine binding 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 +Cyclic nucleotide dependent protein kinase activity 0.3655384615384571 0.0290989681200919 0.9767856587716036 1.0 1.0 2 P54619 1 +Camp dependent protein kinase activity 0.3655384615384571 0.0290989681200919 0.9767856587716036 1.0 1.0 2 P54619 1 +Molybdopterin cofactor binding 0.3535384615384631 0.02884224052724 0.9769904118114836 1.0 1.0 2 Q9NQX3 1 +Cysteine type peptidase activity 0.2778423092183768 0.0278035567534335 0.977818829181639 1.0 1.0 45 Q96FW1,Q9H8M7,Q9Y4P1,P51784,Q9UDY8,Q92905,P53634,O15372,P04632,O00303,Q96K76,Q92820,Q9BT78 13 +Primary mirna binding 0.3493382579255203 0.0268778903533721 0.978557128087964 1.0 1.0 3 P40763,Q8WYQ5 2 +7s rna binding 0.2757239679605732 0.0214360838818722 0.9828977893971288 1.0 1.0 6 P37108,Q9UHB9,P61011,Q13868,P49458 5 +Glutathione oxidoreductase activity 0.2988611880578689 0.0200259876421647 0.984022641579744 1.0 1.0 3 Q16881,Q86SX6 2 +Tumor necrosis factor receptor superfamily binding 0.2506157635467879 0.0185950153357732 0.985164179335602 1.0 1.0 4 Q9NXR7,Q13546,P42224 3 +Cation transmembrane transporter activity 0.3242093364496559 0.0182199543524317 0.98546338400694 1.0 1.0 74 Q9HD20,Q9Y619,Q70HW3,P00403,Q9UDW1,P24539,Q8TAD4,O75964,Q9Y487,Q86VD7,Q9HC07,O43772,Q93050 13 +Phosphoserine residue binding 0.2750230982445296 0.0181712428937476 0.985502243694393 1.0 1.0 5 P46934,P62258,Q92541,Q13526 4 +Lamin binding 0.2883684229307717 0.0172764400013671 0.9862160809540934 1.0 1.0 9 Q9UH99 1 +Wd40 repeat domain binding 0.2444581280788096 0.0167393022735054 0.9866445928672224 1.0 1.0 4 Q16531,P40227,Q96K76 3 +Mitochondrial ribosome binding 0.2361453201970351 0.0146262919442107 0.9883303235566352 1.0 1.0 4 Q07021,Q92552,Q15070 3 +Signal recognition particle binding 0.266399753618723 0.0111246938300043 0.9911239616310868 1.0 1.0 5 Q9UHB9,P49458,O76094,Q9BUN8 4 +Carbohydrate binding 0.2747128449718538 0.0107849126996323 0.991395051480834 1.0 1.0 45 Q13438,P11717,P35573,O15460,P11413,O75503,P52789,P10253,O00754,O00462,Q32P28,Q10472 12 +Phosphatidylinositol bisphosphate binding 0.3004166966998902 0.0068496896052349 0.9945347811541398 1.0 1.0 17 O00560,P07737,Q92538 3 +Syntaxin binding 0.2984513052021814 0.0030287453405045 0.9975834145488848 1.0 1.0 19 Q15833,Q6ZWJ1,O60499 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ade3a08daf9316a66a577721876b856b9957a288 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Benzodiazepine receptor binding", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Bmp receptor binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein lipase activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Neuregulin binding", "Neurexin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol n acetylglucosaminyltransferase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor serine threonine kinase binding", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur amino acid transmembrane transporter activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL8A", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRIP", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD5", "C6orf89", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPV", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COG2", "COIL", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHDC", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRGQ", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "ITSN2", "IVD", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFS1", "NFU1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPCS2", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM38B", "TMEM43", "TMEM59", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", 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6.494328716879693e-05 5.650922597265324e-05 +Skin nodule 12 22 2.2381924219607905 0.0252085096268335 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.0296670659434343 0.0366902203239334 0.0231701844530087 0.0042402736300421 0.0033531788386621 +Exaggerated startle response 2 8 2.206041002098681 0.0273811289714354 2.987864077669903 8.699029126213592 0.0610274034602423 0.2634753902852135 1.4337635656228835 1.0620090089420118 1.617556501702403 0.2831541938798349 0.0024567571854954 1.0 0.1362380906066266 0.0052676758380378 0.0341598187242075 +Abnormal macrophage morphology 4 6 2.1856666124479496 0.028840005268202 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 0.0029825309032257 0.0742352733278267 0.144637307685789 2.923978855186412e-05 0.0007664910713946 +Foam cells 3 6 2.177828866718229 0.0294187799257761 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 0.0003329397892747 0.0378187125466048 0.075113296023457 2.2502069418558096e-05 0.0003389453461558 +Exercise induced muscle cramps 1 6 2.13757561335515 0.0325512027531027 1.3155339805825244 5.674757281553398 0.579896045951168 0.4229644702211388 0.9282259184279634 0.5176906236976432 0.9588843996375666 0.2865668825551565 0.0114093616288019 1.0 1.0 0.0190953097419897 0.0684923167064351 +Abnormal epiglottis morphology 1 5 2.135173120621607 0.0327468716448433 1.145631067961165 4.138349514563107 0.0455794526781296 0.4003298365054372 1.1096029814805428 0.7868982948153208 1.197451485181648 0.2907678047097171 0.0349220856805398 0.0742352733278267 0.144637307685789 0.0569248849368824 0.1829832713301316 +Abnormal morphology of the conjunctival vasculature 3 9 2.1280191310197902 0.0333354974337023 2.6359223300970873 7.330097087378641 0.3791669082255805 0.3264494094231241 1.4642904354684148 1.4524057679745994 1.3542312898692437 0.2989163062985944 0.0003636586048315 0.0875404472016038 0.1693528922958147 0.0010078083449561 0.0122181482786312 +Subcutaneous nodule 8 18 2.087791531012611 0.03681664385487 5.174757281553398 17.716019417475728 0.7715929851765809 0.3892857335439222 2.3624373807533945 1.5246949972287631 1.0645096840549642 0.3076166958299045 0.017902984385184 0.0276250495673642 0.0154029461510805 0.0019334595315902 0.0011118846580662 +Abnormal urine carbohydrate level 5 12 2.0827116432803874 0.0372775155091349 3.883495145631068 11.70631067961165 -0.1388020161424021 0.4168246977061866 1.9096127339504616 1.3287920569685254 1.2303643442685093 0.3136870898203888 0.0001759741669303 1.0 1.0 0.0006131602837479 0.0024174147434085 +Loss of speech 7 18 2.06735850132638 0.0387003855391485 5.453883495145631 19.1626213592233 0.4726173662677797 0.3013153148889984 2.223071754411353 1.8941045281154043 1.521023928928509 0.3006842241053739 0.0075253280215789 0.0172375696548913 0.0077496201950681 0.0033942963153933 0.0008418064991302 +Abnormal circulating ceruloplasmin concentration 3 5 2.0376715378942003 0.0415827924352507 0.7160194174757282 2.8859223300970873 1.0233092803757249 0.3046680125137628 0.7500392738012596 0.9922495153757964 1.1063683830556137 0.2687740636521534 0.1067523261322923 0.028497516818446 0.0568757538574934 0.1378997973237242 0.002085627724241 +Urinary glycosaminoglycan excretion 3 7 2.0277261517679888 0.0425882050260433 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.0001357736334811 0.0697581245313758 0.0090253131212995 0.0003832983840783 0.0050247198439474 +Abnormal liver physiology 2 6 2.020293390912111 0.0433529639477481 1.546116504854369 5.524271844660194 0.1136348692144798 0.4096579041009897 1.127894105242248 0.8656852069642818 1.118688697140881 0.2890142734073779 0.1869956416977375 0.0516364610584135 0.1018169846714528 0.2382253475836706 0.0981576275361481 +Neoplasm of the adrenal cortex 2 6 2.0185430649397245 0.0435347338056977 1.9029126213592231 5.502427184466019 0.279284275131131 0.3518731642920829 1.1804603603119783 0.9766665776615882 1.363400785954724 0.3120205744103949 0.0391020467975167 0.0786913117950012 0.0115435449528709 0.0635022977163126 0.0475092322455766 +Infantile axial hypotonia 4 11 2.016936366629484 0.043702154339015 3.0970873786407767 9.91747572815534 0.2141703344813526 0.3664899290512883 1.6385203075306134 1.5973234399272347 1.21609252960959 0.2741067096589152 0.1070428504887252 0.134742527043449 0.03403446937649 0.1658780833937837 0.0142164369771549 +Delusions 9 21 2.016736039396027 0.0437230668316548 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0269295908928681 0.0121686135974036 0.0046396659223567 0.0100334254948701 4.369045938117462e-06 +Neurofibrillary tangles 3 5 2.01399087512178 0.0440104915202876 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 0.0271332567802568 1.0 1.0 0.0042908003473226 0.003831161384841 +Psychomotor deterioration 3 8 2.013099447082935 0.0441041683994987 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 0.0015872334482998 0.0017062060788896 0.0067896670197663 0.0002086676392486 0.0028454446322632 +Fluctuations in consciousness 3 5 1.9973815899348395 0.0457837461781474 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0479915779418294 1.0 0.0143328298354406 0.0104402688493973 0.0122181482786312 +Emg chronic denervation signs 4 11 1.9864620913457676 0.0469820380880023 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 0.0729450524117466 0.0058373227860703 0.0224191931510111 0.0199432580741765 0.0053941913939985 +Abnormal midbrain morphology 2 8 1.9768803896523408 0.0480551519756851 2.155339805825242 7.762135922330097 0.7338155730112543 0.3990028707572332 1.3492700763379188 1.674109907241791 0.9359553327569134 0.2948227663961126 0.3218575272351821 1.0 0.4548903476361624 0.1927694592715518 0.5908939672340359 +Infectious encephalitis 6 8 1.9757715848128428 0.048180653083452 2.611650485436894 9.322815533980584 0.7677128854878532 0.4486742546959104 1.5963125573496535 1.613102851845623 0.7481836900008295 0.2981059590210475 1.0 1.0 1.0 0.0222629680099487 0.0010642832547548 +Clumsiness 6 19 1.971457556725126 0.048671563172592 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0128831683681083 0.0016453439849387 0.0012677167474155 0.0311941867040692 0.009294722463456 +Ovoid vertebral bodies 2 7 1.9696014702545264 0.0488840630223721 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0066154643028179 0.0963063052639835 0.0173819675279631 0.0138257504316944 0.0805733885782284 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8edcc85c73cb60841714d7f4ac86f256f8d98257 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 4613, + "title": "Average number of proteins per term", + "value": 23.935616735313246 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1874a3f7e1ec984dbd7e0925478d48b6b4b1928f --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37b6d390eb2b7aa910f54d8ba86705cc72ec6c6b --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1142 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Increased cerebral lipofuscin 0.9561662398517502 2.6658053229977736 0.0076804154170559 0.9999999999999996 1.0 6 O75503,P50897,P07602 3 +Cherry red spot of the macula 0.9132136781193688 2.5895043994183538 0.0096114194697196 1.0 1.0 9 P16278,Q13510,P17900,P10619,P07602 5 +Abnormality of lysosomal metabolism 0.8899403766212448 2.404195352489519 0.0162081093301256 1.0 1.0 6 P07602 1 +Dysostosis multiplex 0.8807339316942736 2.39335388225701 0.0166951297214563 1.0 1.0 7 P54802,P15586,P16278,P04066,P10619 5 +Pulmonary infiltrates 0.8727470107644284 2.3606829866844863 0.0182413165071313 1.0 1.0 7 Q9NZ08,Q9UDY8,P04062,Q13510 4 +Abnormal conjunctiva morphology 0.6010510085954459 2.340052032937618 0.0192810534297469 1.0 1.0 29 P06280,Q10567,P28070,P04066,Q13510,P10619,Q15437,P01889,P37287,Q9NZ08,Q14739,O00462 12 +Angiokeratoma 0.9498152709359604 2.3318026017334414 0.0197110781087688 1.0 1.0 4 P06280,O00462,P04066 3 +Oligosacchariduria 0.8713760035989746 2.3293334990427956 0.0198414050381319 1.0 1.0 6 O00462,P10253,P16278,P04066 4 +Abnormality of glycolipid metabolism 0.8514662405521991 2.2730080599707794 0.02302569423523 1.0 1.0 7 P06280,P17900,P07602,P06865 4 +Skin nodule 0.693950080780688 2.2381924219607905 0.0252085096268335 1.0 1.0 22 P06280,P49327,O75874,P34913,Q13510,Q15437,P48735,P01889,Q9NZ08,P52732,P21912,P35637 12 +Mediastinal lymphadenopathy 0.9199507389162558 2.2133609536678875 0.0268727703731079 1.0 1.0 4 Q9UDY8,O15460,P01889 3 +Exaggerated startle response 0.8290497390626194 2.206041002098681 0.0273811289714354 1.0 1.0 8 P17900,P16278 2 +Abnormal macrophage morphology 0.8362081788544029 2.1856666124479496 0.028840005268202 1.0 1.0 6 O15118,P61916,P16278,Q13510 4 +Foam cells 0.834306487527683 2.1778288667182295 0.0294187799257761 1.0 1.0 6 O15118,P16278,Q13510 3 +Abnormal protein o linked glycosylation 0.901496716564956 2.139458412155407 0.0323985605958512 1.0 1.0 4 Q8N511 1 +Exercise induced muscle cramps 0.8245665754278387 2.13757561335515 0.0325512027531027 1.0 1.0 6 P23786 1 +Abnormal epiglottis morphology 0.8634044336531301 2.135173120621607 0.0327468716448433 1.0 1.0 5 Q13510 1 +Abnormal morphology of the conjunctival vasculature 0.8042157254456224 2.1280191310197902 0.0333354974337023 1.0 1.0 9 P06280,O00462,P10619 3 +Erlenmeyer flask deformity of the femurs 0.898457883836333 2.1272373014100476 0.033400371286004 1.0 1.0 4 P07602 1 +Thickened ribs 0.895012315270934 2.113362977809398 0.0345697121811185 1.0 1.0 4 P15586,P54802,P16278 3 +Subcutaneous nodule 0.7155386130053618 2.087791531012611 0.03681664385487 1.0 1.0 18 P06280,O75874,Q13510,Q15437,P48735,P01889,Q9NZ08,P52732 8 +Abnormal urine carbohydrate level 0.7718197356229741 2.0827116432803874 0.0372775155091349 1.0 1.0 12 Q6PGP7,P16278,P04066,P10253,O00462 5 +Loss of speech 0.7116193215522298 2.06735850132638 0.0387003855391485 1.0 1.0 18 P61916,O15118,P17900,Q9UQN3,P50897,O00754,P07602 7 +Abnormal circulating ceruloplasmin concentration 0.8396121449528566 2.0376715378942003 0.0415827924352507 1.0 1.0 5 Q10567,O00400,Q8N511 3 +Urinary glycosaminoglycan excretion 0.7930612664587804 2.0277261517679888 0.0425882050260433 1.0 1.0 7 P54802,P15586,P04066 3 +Vacuolated lymphocytes 0.8734295482318389 2.026038523549152 0.0427608370693768 1.0 1.0 4 P16278,P04066 2 +Abnormal liver physiology 0.79643805504326 2.020293390912111 0.0433529639477481 1.0 1.0 6 Q10567,Q13510 2 +Neoplasm of the adrenal cortex 0.7960210076157764 2.0185430649397245 0.0435347338056977 1.0 1.0 6 O75874,P48735 2 +Infantile axial hypotonia 0.7651594811919644 2.016936366629484 0.043702154339015 1.0 1.0 11 O00754,P17900,Q13509,P07602 4 +Delusions 0.6676353025501254 2.016736039396027 0.0437230668316548 1.0 1.0 21 Q96DF8,Q9BQE5,Q9UI10,O43681,P50336,P29218,P04062,O00754,P07602 9 +Neurofibrillary tangles 0.8338690393986983 2.01399087512178 0.0440104915202876 1.0 1.0 5 P05067,P61916,O15118 3 +Psychomotor deterioration 0.7840384414356981 2.013099447082935 0.0441041683994987 1.0 1.0 8 P50897,P07602,P06865 3 +Saccadic smooth pursuit 0.8684370282945112 2.0057379051376207 0.0448842187674545 1.0 1.0 4 O14773 1 +Undetectable electroretinogram 0.8668476983136908 1.9992675516618423 0.0455794130351814 1.0 1.0 4 P50897 1 +Fluctuations in consciousness 0.8298489401172394 1.9973815899348393 0.0457837461781474 1.0 1.0 5 P04062,O75306,P00403 3 +Emg chronic denervation signs 0.7584808126061695 1.9864620913457671 0.0469820380880023 1.0 1.0 11 P07602,O43681,Q969X5,Q13510 4 +Abnormal midbrain morphology 0.7756938161639136 1.9768803896523408 0.0480551519756851 1.0 1.0 8 P04062,P02792 2 +Infectious encephalitis 0.775438857159192 1.9757715848128428 0.048180653083452 1.0 1.0 8 P01889,P42224,Q15833,Q9NZ08,Q14739,Q9H9P8 6 +Clumsiness 0.6825738769077371 1.971457556725126 0.048671563172592 1.0 1.0 19 Q13510,O43681,O75503,O14773,O00754,P07602 6 +Ovoid vertebral bodies 0.7794515965110679 1.9696014702545264 0.0488840630223721 1.0 1.0 7 P15586,P54802 2 +Chorioretinal degeneration 0.8578371474429624 1.9625139837319296 0.0497026741833224 1.0 1.0 4 Q9Y619 1 +Chorioretinal atrophy 0.8578371474429624 1.9625139837319296 0.0497026741833224 1.0 1.0 4 Q9Y619 1 +Meningitis 0.7769815570549258 1.9590138757102025 0.0501111618065222 1.0 1.0 7 Q8TAA9,O15460,Q9NZ08 3 +Abnormal circulating copper concentration 0.7807026768312855 1.9540242280154148 0.0506983519930341 1.0 1.0 6 Q10567,Q9Y487,Q15904 3 +Respiratory arrest 0.8191089531554314 1.9528762771772357 0.0508342573324067 1.0 1.0 5 P23786,P13473 2 +Bone pain 0.6297785371575405 1.9416065639114983 0.0521847476591232 1.0 1.0 23 O75874,P07602,Q14108,P48735 4 +Abnormal autonomic nervous system physiology 0.496764658955335 1.931757601817211 0.0533894314261718 1.0 1.0 33 P06280,P42892,O43681,Q13509,P50336,P0DP25,P41440,P04062,P07602 9 +Abnormal lower motor neuron morphology 0.7700221352303368 1.9291200242686848 0.0537159636412873 1.0 1.0 7 Q9UQN3,Q13510 2 +Endocarditis 0.8115056325365572 1.921253972910442 0.0546996967378552 1.0 1.0 5 P04062,Q9NZ08,P01889 3 +Congenital hepatic fibrosis 0.8108216347900914 1.918404600849703 0.0550597281306841 1.0 1.0 5 Q96EX3 1 +Lateral clavicle hook 0.8442521599008173 1.9068790651103904 0.0565362497173347 1.0 1.0 4 Q9Y619 1 +Macular degeneration 0.7166194174299655 1.8987627432705472 0.0575956778023507 1.0 1.0 14 P50897,P04062,Q13510 3 +Chondrosarcoma 0.8420566502463023 1.8978631647151372 0.0577141098171756 1.0 1.0 4 O75874,P48735,Q92804 3 +Arthritis 0.5139470963272689 1.8875936031387277 0.0590805295164931 1.0 1.0 44 P06280,P49327,Q93063,P28070,Q13510,Q9UBS4,Q8WVQ1,Q14739,Q96HY6,P21964,Q14108,Q96RL7,O75844,Q9NZ08,P04062,O00192,P10321,O15460,P01889 19 +Neoplasm of the parathyroid gland 0.8029503172605899 1.8855603406350652 0.0593542259757515 1.0 1.0 5 O75874,P48735 2 +Parathyroid adenoma 0.8029503172605899 1.8855603406350652 0.0593542259757515 1.0 1.0 5 O75874,P48735 2 +Decerebrate rigidity 0.8361726386171986 1.873667338379988 0.0609762903832336 1.0 1.0 4 P07602,P16278 2 +Decreased circulating copper concentration 0.8358343438641398 1.872274776617111 0.0611685985044392 1.0 1.0 4 Q10567,Q15904 2 +Abnormal pulmonary interstitial morphology 0.5341209304719026 1.8647987958331425 0.0622096121605044 1.0 1.0 29 Q13510,Q14108,P09601,P04062,Q8IZA0 5 +Biliary cirrhosis 0.7582891871982218 1.8588323270870757 0.0630509087365904 1.0 1.0 6 P09601,Q9UJW0,Q14739 3 +Hallucinations 0.5159074672418126 1.8549777883463852 0.0635993984869165 1.0 1.0 47 Q9BQE5,O60313,Q6DKK2,O43681,P05067,P50897,O75503,P50336,P04062,P35637,O00754,P07602 12 +Abnormality of the thoracic cavity 0.7411075253368646 1.8494694074914573 0.0643900612981966 1.0 1.0 9 Q9UDY8,O15460,P01889 3 +Cerebral palsy 0.7409583419925189 1.8488014604408705 0.0644864864106733 1.0 1.0 9 O75874,P35270,P48735 3 +Skin ulcer 0.4994991826771697 1.839110280784117 0.0658989671831946 1.0 1.0 31 O75874,Q03518,O15460,P48735,P01889,Q14739,Q8IZA0,P52732,P04062 9 +Multiple enchondromatosis 0.7528238261145831 1.8354815184254816 0.0664343750158535 1.0 1.0 6 P48735 1 +Punctate cataract 0.7883383922607496 1.824330247427539 0.0681021602311577 1.0 1.0 5 Q9H6K4,P02792 2 +Progressive spastic quadriplegia 0.7408565901038351 1.8242016170355215 0.0681215972350606 1.0 1.0 8 P17900,P07602 2 +Enlarged ovaries 0.8217364532019679 1.8141050717901164 0.0696615508892761 1.0 1.0 4 P10644,P21912,Q15437 3 +Abnormality of corneal stroma 0.6986269307159676 1.8106461314580111 0.070195646401266 1.0 1.0 14 P10619,P04062,Q13510 3 +Varicose veins 0.7452623351793186 1.8030872132302485 0.0713745189819754 1.0 1.0 6 O00192,P04062 2 +Venous insufficiency 0.7452623351793186 1.8030872132302485 0.0713745189819754 1.0 1.0 6 O00192,P04062 2 +Abnormal circulating acetylcarnitine concentration 0.7440149569081713 1.7977336176266072 0.072219231354395 1.0 1.0 6 P23786,P40939 2 +Abnormality of pulmonary circulation 0.5247755641030503 1.7966744726228712 0.0723873138363704 1.0 1.0 29 P00403,Q14108,O75844,Q9NZ08,Q9UMS0,Q8IZA0,P04062 7 +Hypersplenism 0.7317699100599592 1.7839995318995556 0.0744237412225543 1.0 1.0 8 Q14108,P07602 2 +Hepatic fibrosis 0.4806095891436904 1.7834883062183784 0.0745068498590633 1.0 1.0 34 Q10713,Q6PGP7,Q13510,Q15904,P04062,Q9H0F7,Q96EX3 7 +Weak voice 0.7358226533627157 1.7808998594095262 0.0749288116079949 1.0 1.0 7 P04062 1 +Hypoplastic vertebral bodies 0.7388419226626727 1.7755026606474715 0.0758149266275225 1.0 1.0 6 P10644,Q8TAA9,Q14739,P16278 4 +Joint subluxation 0.7383453525005481 1.7733662288258845 0.0761680412098031 1.0 1.0 6 Q9UHX1 1 +Pericarditis 0.775793039728966 1.7714993565845043 0.0764776995828306 1.0 1.0 5 P49327,Q9NZ08,O15460,P01889 4 +Oculomotor apraxia 0.5756422366790359 1.7647707682750835 0.0776022993611103 1.0 1.0 25 P35270,Q10713,P05067,Q13509,O14773,P04062,Q9NQT5 7 +Mucosal telangiectasiae 0.714380734801168 1.7544854179004317 0.0793473663841188 1.0 1.0 10 P06280,P10619,Q15437,Q14739,Q8IZA0 5 +Exostoses 0.7707920570579057 1.750374463684725 0.0800537194507082 1.0 1.0 5 P48735 1 +Photophobia 0.4813571955814262 1.739198347374064 0.0819998800633523 1.0 1.0 37 P04080,Q10567,Q8WWY3,Q86YV9,P01889,P40939,P51648,Q8WWV3,Q9NZ08,Q9H0F7,P07602 11 +Hemoptysis 0.8035714285714258 1.7387761513779751 0.0820741450789541 1.0 1.0 4 P31153,Q9NZ08,P01889 3 +Pulmonary embolism 0.8035714285714259 1.7387761513779751 0.0820741450789541 1.0 1.0 4 P37287,Q9NZ08,P01889 3 +Multifocal cerebral white matter abnormalities 0.7670123350828706 1.7343845028819946 0.0828498828957196 1.0 1.0 5 Q9Y619 1 +Periventricular white matter hyperintensities 0.7145393883295048 1.729848543335346 0.0836573388149291 1.0 1.0 9 O75503,P07602 2 +Occipital encephalocele 0.8003745536507658 1.7254772810338943 0.0844414946431384 1.0 1.0 4 Q6ZXV5,Q10713 2 +Progressive psychomotor deterioration 0.7184400840518615 1.7247537447673975 0.0845718608668484 1.0 1.0 8 P07602,O43681,Q10713,P16278 4 +Hypoketotic hypoglycemia 0.720982398779494 1.7159279251945505 0.0861752349022961 1.0 1.0 7 P23786,P40939 2 +Trichorrhexis nodosa 0.797578877800098 1.713837589150467 0.0865585577904255 1.0 1.0 4 Q6PGP7,Q15477 2 +Abnormal anterior horn cell morphology 0.7221483716753505 1.703451683367662 0.0884835726780912 1.0 1.0 6 Q13510 1 +Intracellular accumulation of autofluorescent lipopigment storage material 0.974257649807694 1.691690946590334 0.0907049155247659 1.0 1.0 3 O75503 1 +Goiter 0.6997285687313803 1.6869822425221692 0.0916067665081601 1.0 1.0 10 O75874,P48735 2 +Occipital meningocele 0.7161094246359474 1.6772735524299656 0.0934890018295471 1.0 1.0 6 O00192,Q10713 2 +Perseveration 0.7121279483272129 1.6769839185290731 0.0935456265683341 1.0 1.0 7 Q9UQN3,P61916 2 +Hypertensive crisis 0.7138785386293958 1.667588139015818 0.0953975144125656 1.0 1.0 6 O00192,P01889 2 +Neuronal loss in basal ganglia 0.7852600433189352 1.6624437566398225 0.0964238316188803 1.0 1.0 4 O75306 1 +Aortic dissection 0.7828166124269902 1.6522303125789997 0.0984876092685929 1.0 1.0 4 O15460,P01889 2 +Abnormal circulating cholesterol concentration 0.4607005230847533 1.63653451121842 0.1017277689968212 1.0 1.0 33 P61916,Q8N511,Q9NVI7,Q7Z5J4,Q15904,Q15392,P37268,P07602 8 +Abnormal arachnoid mater morphology 0.6983321559144028 1.6348004062039576 0.1020908956052539 1.0 1.0 8 Q9UHX1,Q15904 2 +Central hypoventilation 0.7053823173030981 1.6306303991818256 0.1029683307644218 1.0 1.0 6 Q8N183,O75306 2 +Agitation 0.4590473532008536 1.622829067651307 0.1046259500992723 1.0 1.0 33 P42892,P05067,Q9UQN3,P10644,Q709C8,Q92804,P04062,P52732,P35637 9 +Paresthesia 0.5650957664455311 1.618704532919755 0.1055108511132432 1.0 1.0 24 P06280,P54802,P05067,O15460,Q9H6K4,Q9NZ08 6 +Memory impairment 0.460452719421359 1.6175477158820526 0.1057601045606728 1.0 1.0 34 Q9UI10,P00403,O43681,Q9UQN3,P05067,P01889,Q9NZ08,P07602 8 +Parkinsonism 0.4711949789240192 1.6150157135057144 0.1063072920534169 1.0 1.0 31 P05067,Q9UQN3,P04062,Q709C8,P07602,P02792,P35637 7 +Unexplained fevers 0.7015388594469104 1.6138754499882644 0.1065544446971338 1.0 1.0 6 P07602 1 +Acetabular dysplasia 0.6921164153954337 1.6068600457242153 0.108085072704279 1.0 1.0 8 Q9Y584,P16278 2 +Unusual infection by anatomical site 0.6643366873834577 1.6062253095509704 0.1082244142975172 1.0 1.0 13 Q8TAA9,O15460,P01889,Q15833,Q9NZ08,Q14739,Q9H9P8 7 +Abnormal cartilage morphology 0.6553108869879699 1.5956473083593177 0.1105675589294845 1.0 1.0 14 O75874,P48735 2 +Recurrent aspiration pneumonia 0.6951497082669371 1.5859745101561615 0.1127450919133425 1.0 1.0 6 Q13510 1 +Abnormal visual fixation 0.7312252631453847 1.58204025546836 0.1136403809957464 1.0 1.0 5 Q13510 1 +Schizophrenia 0.5902581042812766 1.5714119793364227 0.1160869852052584 1.0 1.0 21 Q9BQE5,O43681,P04062,P07602,O00192,Q9UET6 6 +Atlantoaxial abnormality 0.7633098678345176 1.570481355870158 0.1163031685226689 1.0 1.0 4 Q8NCH0,Q9NWM8 2 +Elevated pulmonary artery pressure 0.5569735591953537 1.5671779429061865 0.1170731046207285 1.0 1.0 24 P00403,Q14108,O75844,Q9UMS0,Q8IZA0,P04062 6 +Abnormal substantia nigra morphology 0.9413790049009764 1.566583056810115 0.1172121807353465 1.0 1.0 3 P04062 1 +Small earlobe 0.6901449961649908 1.564078258753406 0.117799191047113 1.0 1.0 6 P98175,O00192 2 +Chronic pulmonary obstruction 0.6825986727248844 1.5639613758157649 0.1178266393009845 1.0 1.0 8 P06280,O00192,P09601 3 +Impaired mastication 0.6863233912503632 1.5627780685941384 0.1181048043988926 1.0 1.0 7 O15460,P01889 2 +Sea blue histiocytosis 0.940289319790705 1.5624285541270668 0.1181870647355007 1.0 1.0 3 P16278,O15118 2 +Heparan sulfate excretion in urine 0.937042800083307 1.5500485814646066 0.1211298560170943 1.0 1.0 3 P15586 1 +Proportionate short stature 0.4498630494330405 1.5464373486355565 0.1219989799789835 1.0 1.0 33 Q7RTS9,P16278,P10619,P10644,P40939,Q15392,Q14739,P52732,Q9Y619,P21912 10 +Abnormality of the parathyroid morphology 0.6827523500476633 1.531671057970586 0.1256036278452164 1.0 1.0 6 O75874,P48735 2 +Biliary tract neoplasm 0.7528516543129926 1.5265138627985828 0.1268819406848413 1.0 1.0 4 P07602 1 +Neoplasm of the gallbladder 0.7528516543129926 1.5265138627985828 0.1268819406848413 1.0 1.0 4 P07602 1 +Breech presentation 0.6697974320169229 1.5256084161343202 0.1271074148906334 1.0 1.0 9 Q9Y619,O75718,Q969X5 3 +Supranuclear gaze palsy 0.5919699423271602 1.5241285036093368 0.1274766136412537 1.0 1.0 20 P07602,P04062,O15118,P02792 4 +Abnormal pericardium morphology 0.6694463292159339 1.5239933156961496 0.1275103809649491 1.0 1.0 9 Q14108,Q9NZ08,O15460,P04062 4 +Cerebral inclusion bodies 0.6393372502016125 1.5154452273101706 0.1296596912211951 1.0 1.0 14 P04062,P05067,P61916,O15118 4 +Confusion 0.6085091925090904 1.5151732040692432 0.1297285470684492 1.0 1.0 18 P05067,P40939,P01889,Q9NZ08,Q9Y619 5 +Abnormal sputum 0.7149746595312406 1.5123574994425524 0.1304429407067613 1.0 1.0 5 P31153,Q9NZ08,P01889 3 +Neck flexor weakness 0.7489370432879515 1.5100346395724078 0.1310345855712831 1.0 1.0 4 Q9Y281,P35637 2 +Decreased activity of mitochondrial complex i 0.4573530387907072 1.5083375327583737 0.1314681618259734 1.0 1.0 39 Q70HW3,O75380,O43676,Q9UBX3,Q9Y6M9,O75306,Q9Y584,O75648 8 +Osteolysis 0.4990409883062442 1.5080874003383071 0.1315321594966134 1.0 1.0 28 O75874,O75844,Q14108,P48735 4 +Abnormal tissue metabolite concentration 0.5890885792828516 1.5075894314129343 0.1316596393057758 1.0 1.0 20 P06280,P06865,P17900,O43681,P37287,P07602 6 +Bilateral talipes equinovarus 0.7118054053445946 1.4987362350139906 0.1339420725307616 1.0 1.0 5 Q15392 1 +Low frustration tolerance 0.6712108673955759 1.4954437083679946 0.1347986806494052 1.0 1.0 7 P04062 1 +Biliary tract abnormality 0.4840687841954111 1.4954393722462904 0.1347998115522362 1.0 1.0 29 Q14108,P09601,P04062,Q9H0F7,P07602 5 +Hyperorality 0.7452954560263432 1.4946950321436143 0.1349940514077401 1.0 1.0 4 Q9UQN3 1 +Abnormality of the parathyroid gland 0.5654219832085243 1.4844389682563968 0.1376925031897122 1.0 1.0 22 Q96DF8,O75874,P00403,P10644,P48735,P40939,O00192 7 +Ascites 0.5439673395065298 1.4842847584980887 0.137733392036059 1.0 1.0 24 P61916,O15118,Q13510,Q01844,P10644,Q14108,P04062 7 +Neuronal loss in central nervous system 0.639442318484782 1.48352909221015 0.1379338929199263 1.0 1.0 13 O15118,Q9UQN3,P04062,P35637,P07602 5 +Fasciculations 0.4521293419416571 1.481516142485963 0.1384690865698528 1.0 1.0 38 P06280,P07737,Q13510,Q9BQT8,Q9UQN3,Q92734,P51114,Q969X5,P35637,P07602,Q9NQT5 11 +Abnormal csf protein level 0.6541739028896529 1.4747840373520968 0.1402706141020571 1.0 1.0 10 P07602,P00403,P02792 3 +Pharyngitis 0.91630705682219 1.4709112647470457 0.1413151158363437 1.0 1.0 3 O15460 1 +Abnormal macular morphology 0.5181920017112353 1.4669309062491276 0.1423948520060625 1.0 1.0 26 Q8WWY3,Q13510,Q86YV9,P50897,P51648,P04062 6 +Panhypogammaglobulinemia 0.7042193187155676 1.4660939925269718 0.1426226821307619 1.0 1.0 5 Q6PGP7 1 +Abnormal larynx physiology 0.6416707404650063 1.4652689340044385 0.1428475587570625 1.0 1.0 12 Q9UQN3,P35637,Q92804,Q13510 4 +Hypocholesterolemia 0.6642266154308598 1.4642251102734043 0.1431324514787024 1.0 1.0 7 P07602,Q9NVI7 2 +Enchondroma 0.656201458480027 1.4629431745938075 0.1434829287713812 1.0 1.0 9 P48735 1 +Abnormal blood transition element cation concentration 0.6350453376575023 1.4617556054204657 0.1438081935748485 1.0 1.0 13 Q10567,Q6PGP7,Q15477,Q9Y487,Q15904,P37287 6 +Lipoma 0.6665895461612219 1.4605724016152184 0.1441328247585094 1.0 1.0 6 Q8TAA9,Q15437 2 +Pituitary adenoma 0.645082393729199 1.4554612671475244 0.1455416056536556 1.0 1.0 11 O75874,P48735,Q9UBS4 3 +Abnormality of fundus pigmentation 0.6993514764029731 1.4451219791240892 0.1484236263417853 1.0 1.0 5 Q9Y619 1 +Abnormal pulmonary thoracic imaging finding 0.5871455954040431 1.444741592349224 0.1485304824647979 1.0 1.0 19 P04062,Q9UDY8,Q9NZ08,Q13510 4 +Frontotemporal dementia 0.6471592514042337 1.441837333350566 0.1493482681878664 1.0 1.0 10 P05067,Q9UQN3 2 +Insidious onset 0.7294842030006089 1.4279984320277308 0.153292309832087 1.0 1.0 4 P04062 1 +Calvarial hyperostosis 0.6951923962169574 1.427188631584008 0.1535255304541178 1.0 1.0 5 P10644 1 +Inflammation of the large intestine 0.6331023861364503 1.423551359400678 0.1545763847038321 1.0 1.0 12 Q6PGP7,Q15477,P01889,P42224,Q15833,P08183 6 +Increased intracranial pressure 0.6063756139576371 1.4182753490431803 0.156110390754198 1.0 1.0 16 P10644,Q15437,P01889,Q9NZ08,P07602,P21912 6 +Primitive reflex 0.6536134588923652 1.4166766686409749 0.1565774814537759 1.0 1.0 7 P17900,P40939 2 +Cholestatic liver disease 0.6561481055198917 1.4144796659454677 0.1572211136085519 1.0 1.0 6 P40939 1 +Brain imaging abnormality 0.434842637454602 1.4038113746486025 0.1603750259160425 1.0 1.0 34 P00403,Q9UQN3,Q7Z5J4,Q05086,P35610,Q9BU61,Q969X5,P07602,O75306 9 +Everted upper lip vermilion 0.6531490039566831 1.4012193846976986 0.1611484793012634 1.0 1.0 6 Q7Z5J4,P04062,P41227 3 +Aplasia hypoplasia of the patella 0.7216748768472852 1.3950107920247188 0.1630125852016219 1.0 1.0 4 Q9Y5S9,Q9Y619,Q96AY3 3 +Abnormality of the pulmonary veins 0.6515888227534005 1.3943176980919894 0.1632216888434823 1.0 1.0 6 Q15392 1 +Osteoarthritis 0.6321293466463099 1.393447885572361 0.163484393849397 1.0 1.0 11 Q14108,O75844,P04062 3 +Abnormal meningeal morphology 0.5296738355782766 1.3927020753951445 0.1637099007663278 1.0 1.0 24 P31153,Q8TAA9,Q9UHX1,Q10713,Q9UBS4,Q15904,O00192 7 +Abnormal urine cytology 0.4431201288979765 1.3899609752847804 0.1645407279842436 1.0 1.0 39 P06280,O15460,Q9UBS4,Q14108,P09601,P04062 6 +Exercise intolerance 0.4360110041855866 1.3801555199248603 0.1675387659162521 1.0 1.0 36 P00403,P23786,P40939,Q9H2D1,P13473 5 +Abnormal circulating ferritin concentration 0.6419081686262671 1.3791822653814598 0.1678385646047573 1.0 1.0 8 Q15833,P02792 2 +Abnormal endocardium morphology 0.6122644040323831 1.378592566701866 0.1680204096821103 1.0 1.0 14 P06280,P10644,P01889,Q9NZ08,P04062 5 +Arteriosclerosis 0.5986351193780725 1.377417089160942 0.1683833323618218 1.0 1.0 16 O75844,O15118,P16278,Q13510 4 +Abnormal heart sound 0.7160203670295407 1.3711118251511172 0.1703400992450445 1.0 1.0 4 P10253 1 +Nasogastric tube feeding in infancy 0.6312823080928861 1.367051160588335 0.1716092701120852 1.0 1.0 10 P07602,Q9UHX1,O75648 3 +Breathing dysregulation 0.7142293818380635 1.3635403088459277 0.1727122897444637 1.0 1.0 4 Q10713 1 +Corneal erosion 0.7124647974403697 1.3560796808609126 0.1750738171052199 1.0 1.0 4 P51648,P01889 2 +Astrocytoma 0.6260695311521314 1.342440325287108 0.1794532670594257 1.0 1.0 10 P48735 1 +Emg neuropathic changes 0.5411921772155558 1.337252358021608 0.1811402764774923 1.0 1.0 22 Q13510,O43681,Q969X5,O14773,P07602 5 +Abnormal vascular physiology 0.4575633787173598 1.3329516571917852 0.1825476687756444 1.0 1.0 50 P06280,P00403,P05067,O15460,P01889,P42224,Q14108,O75844,Q9NZ08,Q9NWM8,Q14739,Q8IZA0,Q9UMS0,Q15056,P04062 15 +Ventricular hypertrophy 0.4321986115842366 1.3315750996696465 0.1829998517761137 1.0 1.0 37 P06280,P23786,P40939,O75844,P10253,Q9H0F7,O43772 7 +Corneal opacity 0.4661680804247388 1.3259438789131377 0.1848582873007869 1.0 1.0 55 P06280,O00754,P16278,Q13510,P04066,Q15056,P10619,Q9NVI7,P51648,O75844,P04062,P52732,Q06136 13 +Cataplexy 0.7053295484059063 1.325906530671768 0.184870659545675 1.0 1.0 4 O15118 1 +Movement abnormality of the tongue 0.7050239821273544 1.3246142320914944 0.1852991330564704 1.0 1.0 4 P10253 1 +Neoplasm of the pituitary gland 0.6070083266926162 1.322330968678456 0.1860579647223561 1.0 1.0 13 O75874,P48735,Q9UBS4 3 +Arterial thrombosis 0.6326204897285919 1.3222955846645097 0.1860697424773381 1.0 1.0 7 P37287,Q9NZ08,O15460,P01889 4 +Abnormal serum iron concentration 0.6706994701680027 1.3213553747953186 0.1863828981710567 1.0 1.0 5 Q6PGP7,Q15477 2 +Abnormal vitamin b12 level 0.6702168956519312 1.319267239736694 0.1870797859824182 1.0 1.0 5 P49327,Q96EY8,P41440 3 +Enlarged kidney 0.6313673638675621 1.3166502085906766 0.1879559007208082 1.0 1.0 7 P23786 1 +Postaxial foot polydactyly 0.6226852923884444 1.307554797759792 0.1910243571006886 1.0 1.0 9 Q10713,Q96EX3 2 +Abnormality of the 5th toe 0.6226852923884444 1.307554797759792 0.1910243571006886 1.0 1.0 9 Q10713,Q96EX3 2 +Tics 0.6671328428505441 1.305920481540693 0.1915796006682233 1.0 1.0 5 Q9UHX1,P46109 2 +Joint swelling 0.6289627462565157 1.3058142944288016 0.1916157177731814 1.0 1.0 7 P06400,P14174,Q13510 3 +Bifid tongue 0.6658886241852149 1.300535092734033 0.1934176367753626 1.0 1.0 5 Q6DKJ4,Q96EX3 2 +Respiratory failure requiring assisted ventilation 0.6656456141312819 1.2994832147845443 0.1937781501831417 1.0 1.0 5 P10253,O75648 2 +Abnormal cervical spine morphology 0.6638503826534565 1.2917120168728162 0.1964568943431039 1.0 1.0 5 P04066 1 +Dementia 0.4666040354222059 1.2836813755801255 0.1992534636322087 1.0 1.0 58 P04080,P61916,O15118,P06865,Q13510,O60313,P00403,Q9UQN3,P17900,P05067,Q9Y487,O43681,Q14108,P04062,P02792,P07602,P35637 17 +Brittle hair 0.5935082004308111 1.2832523678256809 0.1994036744923621 1.0 1.0 14 O75844,Q9NVI7,Q6PGP7,Q9Y487 4 +Aplasia hypoplasia of the sacrum 0.8671150190475347 1.2831544384317852 0.1994379746486023 1.0 1.0 3 Q8TAA9 1 +Abnormal biliary tract morphology 0.5016455569883383 1.2796558555674438 0.2006661963966372 1.0 1.0 25 Q10713,O43681,Q14108,P09601,P04062,P07602 6 +Multiple prenatal fractures 0.6218500461970885 1.273741302129488 0.2027551137791903 1.0 1.0 7 Q15650,O75718,Q32P28 3 +Respiratory failure 0.4705543785378513 1.2706733031347022 0.2038448969333977 1.0 1.0 61 P61916,Q70HW3,Q13510,Q8N183,Q9UQN3,P23786,P40939,P10253,Q9UMS0,Q92804,P07602,Q9Y619,O75306 13 +Abnormal circulating proline concentration 0.6922114888683346 1.2704276948578197 0.2039323233302039 1.0 1.0 4 O96000 1 +Multifactorial inheritance 0.6007455884251722 1.2652791767949798 0.2057712683886059 1.0 1.0 12 P42892,P10321 2 +Patchy changes of bone mineral density 0.86161985426971 1.2622247539208358 0.2068679238158655 1.0 1.0 3 Q13126 1 +Abnormal branching pattern of the aortic arch 0.6896551724137878 1.2596184423578258 0.2078070393231206 1.0 1.0 4 Q96DF8,O00459,Q9H7D7 3 +Paranoia 0.6186361740319014 1.2592401340539876 0.2079436092907491 1.0 1.0 7 Q96DF8,P50336 2 +Tetany 0.61994805535871 1.2539341672487458 0.2098659348706064 1.0 1.0 6 O00192 1 +Happy demeanor 0.6881609622528393 1.253300876318429 0.2100962296490121 1.0 1.0 4 Q15907,Q05086 2 +Chronic hepatic failure 0.6877416960933734 1.2515283011137086 0.2107417948778929 1.0 1.0 4 P40939 1 +Progressive neurologic deterioration 0.5528995066218232 1.2511105967975378 0.2108941299131355 1.0 1.0 19 P54802,Q10713,P16278,P04062,P07602 5 +Pituitary growth hormone cell adenoma 0.6870266358011684 1.2485052694391792 0.2118460798852903 1.0 1.0 4 Q9UBS4 1 +Neuroinflammation 0.6858973826849021 1.2437314525559455 0.2135984160650967 1.0 1.0 4 Q9NZ08,P01889 2 +Abnormal renal vascular morphology 0.6524268961025906 1.2422489429584138 0.2141447268331795 1.0 1.0 5 P21912,P42224 2 +Abnormal placenta morphology 0.6046892626752152 1.2412789879138348 0.2145027041130371 1.0 1.0 10 O75844,Q6PGP7 2 +Flattened epiphysis 0.6849748325496268 1.2398317277546564 0.2150376402657472 1.0 1.0 4 Q8WVQ1 1 +Long toe 0.6139194854575218 1.2379499094565267 0.215734634587704 1.0 1.0 7 Q9UHX1,P23786 2 +Nuclear cataract 0.6154424428391978 1.233896701290168 0.2172413988929515 1.0 1.0 6 P02792 1 +Dyschromatopsia 0.6098989095006028 1.232686666366787 0.2176926883705996 1.0 1.0 8 Q9H6K4,Q9H061 2 +Angiofibromas 0.6822231991055661 1.2282018906233616 0.2193711891632257 1.0 1.0 4 Q15437 1 +Adenoma sebaceum 0.6822231991055661 1.2282018906233616 0.2193711891632257 1.0 1.0 4 Q15437 1 +Colitis 0.6045175489130225 1.222952555420921 0.2213476166185035 1.0 1.0 9 P49327,Q6PGP7,Q15477,P42224,Q15833 5 +Abdominal distention 0.4930139492725411 1.2222557777853973 0.2216109167358855 1.0 1.0 25 Q9Y366,Q01844,O43681,P04062,P07602,Q96EX3,O75648 7 +Retinal dysplasia 0.6094895775698218 1.2179469558268528 0.2232441308002961 1.0 1.0 7 Q10713,P52732 2 +Mutism 0.580577101366072 1.2173573161043447 0.2234682957139853 1.0 1.0 14 P02792,Q9UQN3,Q13510 3 +Micrographia 0.8487622097340355 1.2133260503867016 0.2250051869025622 1.0 1.0 3 P04062 1 +Bilateral tonic clonic seizure with generalized onset 0.5984271939586584 1.211602914889549 0.2256644182415255 1.0 1.0 10 Q05086,P04062,Q13510 3 +Increased bone mineral density 0.4806069301591548 1.2102073983094928 0.2261993199299441 1.0 1.0 26 P54802,Q14108,Q15392,Q14739,P04062,Q15056,Q13126 7 +Gastritis 0.6445901894372699 1.2083139130867808 0.226926538800984 1.0 1.0 5 Q6PGP7,Q15477 2 +Inappropriate behavior 0.566455390240312 1.2068584336510804 0.2274866678148792 1.0 1.0 16 P17900,Q9UQN3,P07602 3 +Cortical cataract 0.8459398900201021 1.2026087176518514 0.2291277725759801 1.0 1.0 3 Q9H6K4 1 +Psychosis 0.4326224201356167 1.200182773778247 0.2300683639897727 1.0 1.0 30 P61916,P00403,O15118,Q6DKK2,Q9UQN3,P50336,P02792 7 +Abnormal large intestine physiology 0.5513427616120421 1.199573441501684 0.2303050462687259 1.0 1.0 18 P06280,Q8TAA9,O43681,P46109,P07602,O00192 6 +Abnormal retinal artery morphology 0.5261862712394363 1.191851217137011 0.2333195890796808 1.0 1.0 21 P16278,Q13510,P17900,P10619,P07602 5 +Vasculitis 0.6035439288959362 1.191092229910882 0.2336173798630869 1.0 1.0 7 Q9NZ08,O15460 2 +Frontal lobe dementia 0.6733431625074899 1.1906915831493714 0.2337746833581229 1.0 1.0 4 P02792 1 +Vertebral compression fracture 0.555686803942989 1.1846811351496604 0.2361435440283399 1.0 1.0 17 Q14108,O75718,Q32P28,P04062 4 +Gangrene 0.5913186375467632 1.177902510538224 0.238835474115401 1.0 1.0 10 P49327,P10644,O15460,P01889,Q9NZ08,P52732 6 +Truncus arteriosus 0.5913141626475219 1.1778812933794207 0.2388439337350414 1.0 1.0 10 Q9UHX1,O00192,P46109 3 +Venous thrombosis 0.5670207355224521 1.1772824736894554 0.2390827798899364 1.0 1.0 15 O75874,P10644,P48735,P01889,Q9NZ08,P52732 6 +Macular atrophy 0.6003872862529736 1.176832597546947 0.2392623289948576 1.0 1.0 7 Q8WWY3,P04062 2 +Laryngeal dystonia 0.6360929981573007 1.1715302485731245 0.2413857065532707 1.0 1.0 5 P04350,Q96RL7,P02792 3 +Parkinsonism with favorable response to dopaminergic medication 0.5851935640708932 1.1675021812794697 0.2430076279416866 1.0 1.0 11 P07602 1 +Severe lactic acidosis 0.6676991179089011 1.1668727589923438 0.2432617584004224 1.0 1.0 4 Q70HW3 1 +Zonular cataract 0.5805223533894099 1.1659946895718525 0.2436165925512323 1.0 1.0 12 Q99797,Q9H6K4,P02792 3 +Pericardial effusion 0.6673629344900258 1.1654546712129812 0.2438349983453516 1.0 1.0 4 Q14108 1 +Abnormality of iron homeostasis 0.5996801582559715 1.1637606309296007 0.2445210307436554 1.0 1.0 6 Q6PGP7,Q15477 2 +Abnormal metabolic brain imaging by mrs 0.5696964760284786 1.1618561309130764 0.2452939092230828 1.0 1.0 14 P00403,P35610,Q9BU61,P07602,O75306 5 +Cavernous hemangioma 0.8347183748845811 1.160066512722085 0.2460217269730142 1.0 1.0 3 P50570,Q15437 2 +Abnormal placental size 0.6322290626361352 1.1548112289753587 0.2481677377515008 1.0 1.0 5 O75844 1 +Abnormal choroid morphology 0.4013329948891115 1.1539452722360923 0.2485226068687422 1.0 1.0 32 P04439,Q10713,P50542,P41227,P40939,Q12768,P21359,Q99622,Q9Y5Y5,P52732,Q9Y619,O43505 12 +Abdominal aortic aneurysm 0.8328716528162523 1.1530771996279694 0.2488786991567018 1.0 1.0 3 O15460,P01889 2 +Pancreatic cysts 0.6317114950978547 1.152572226165808 0.2490860085061002 1.0 1.0 5 Q9Y5S9,O15078,Q9UBS4 3 +Alkalosis 0.6316834899384675 1.1524510790638094 0.2491357615984299 1.0 1.0 5 Q9Y619 1 +Oral ulcer 0.5946090133275669 1.1507296543348595 0.2498434727688006 1.0 1.0 7 Q9NZ08,P01889 2 +Motor neuron atrophy 0.5348638233503792 1.1486761956154703 0.25068952502536 1.0 1.0 19 Q13510,Q9UQN3,Q92734,P35637,Q92804 5 +Abnormality of head blood vessel 0.4915262646791553 1.1465406863947802 0.251571502528241 1.0 1.0 24 P16278,Q13510,P17900,P10619,P07602 5 +Arthralgia 0.4129152165867774 1.1430223135275008 0.2530293267940369 1.0 1.0 31 P06280,P28070,Q13510,O15460,P01889,Q9NZ08,P02792 7 +Abnormal erythrocyte sedimentation rate 0.5947850869829197 1.1419772114290525 0.2534634922381569 1.0 1.0 6 O15460,P01889 2 +Orthostatic hypotension due to autonomic dysfunction 0.5863032476933986 1.138030955075053 0.2551075567848997 1.0 1.0 9 P07602,P04062 2 +Central apnea 0.5859855565132355 1.1365497551094093 0.2557265546502485 1.0 1.0 9 P07602 1 +Pulmonary fibrosis 0.53936677752939 1.1330833640301088 0.2571792468108897 1.0 1.0 18 P09601,Q8IZA0 2 +Diffuse white matter abnormalities 0.5881420580825022 1.1328744601000087 0.2572669766885795 1.0 1.0 8 O75306,P16278 2 +Aplasia hypoplasia involving the vertebral column 0.5455075136277285 1.129410086751966 0.258724879729725 1.0 1.0 17 Q6NUQ1,Q8TAA9,Q7RTS9,P16278,P04066,P10644,Q14739,Q04721,Q96HY6 9 +Limb ataxia 0.4688262292931931 1.1293128722446446 0.2587658726724973 1.0 1.0 26 P04080,Q10713,Q8IV08,Q14108,O14773,P04062,P41440 7 +Loss of voice 0.826205911310685 1.1278806547303253 0.2593703248613872 1.0 1.0 3 Q13510 1 +Abnormal aortic valve morphology 0.4155612525029435 1.12667140907251 0.2598814349776468 1.0 1.0 41 P06280,P31153,Q9UHX1,P21964,Q6PGP7,Q7Z5J4,Q15477,P01889,Q6DKJ4,O75844,P37268,P04062,P41227,Q15056,O00192,P61978 16 +Tricuspid atresia 0.6253514533996007 1.1250698840177102 0.2605594218551825 1.0 1.0 5 O00192 1 +Multiple suture craniosynostosis 0.6253514533996007 1.1250698840177102 0.2605594218551825 1.0 1.0 5 O00192 1 +Avascular necrosis 0.5058573476698981 1.1211630095159486 0.2622184819453563 1.0 1.0 22 P01889,Q14108,O75844,Q9NZ08,P04062,Q9Y619 6 +Decreased activity of mitochondrial complex iv 0.5366108649604555 1.1177809494153024 0.2636605598065615 1.0 1.0 18 Q70HW3 1 +Diminished motivation 0.4862097279442335 1.1121327572366406 0.2660810742650392 1.0 1.0 24 P06865,P17900,Q9UQN3,P04062,Q709C8,P35637 6 +Limited extraocular movements 0.6204373754948085 1.1038373697035668 0.2696636910932999 1.0 1.0 5 O75306 1 +Vertebral hypoplasia 0.5715038310951841 1.101465578946414 0.2706940774387645 1.0 1.0 11 Q6NUQ1,Q8TAA9,P16278,P10644,Q14739,Q04721 6 +Lymphangioma 0.980615384615384 1.1012870288426269 0.2707717547353598 1.0 1.0 2 P48735 1 +Hemangiomatosis 0.980615384615384 1.1012870288426269 0.2707717547353598 1.0 1.0 2 P48735 1 +Visceral angiomatosis 0.980615384615384 1.1012870288426269 0.2707717547353598 1.0 1.0 2 P48735 1 +Distal peripheral sensory neuropathy 0.6514964983864244 1.098635218988102 0.2719272093157685 1.0 1.0 4 P40939 1 +Ventricular arrhythmia 0.4082064276012349 1.0971060596124136 0.2725950316241821 1.0 1.0 39 P00403,P42892,P23786,P10253,P0DP25,O43772,O75306,P13473 8 +Vegetative state 0.8179485443910091 1.0967427092664477 0.2727538807099057 1.0 1.0 3 P07602 1 +Progressive peripheral neuropathy 0.8179485443910091 1.0967427092664477 0.2727538807099057 1.0 1.0 3 P07602 1 +Intractable diarrhea 0.6506157872879847 1.09493353789375 0.2735457547132707 1.0 1.0 4 Q6PGP7 1 +Ventricular tachycardia 0.5614904889041966 1.0947384755354743 0.2736312272400716 1.0 1.0 13 O43772,P23786 2 +Hypoparathyroidism 0.5612695982621927 1.0936335962275776 0.2741157083787868 1.0 1.0 13 Q96DF8,P40939,O00192,P00403 4 +Furrowed tongue 0.5836796395505993 1.0925767778865847 0.2745796632511752 1.0 1.0 6 P21912,Q15437,P61978 3 +Abnormal intraocular pressure 0.6171087277606695 1.0894654108674928 0.2759487000082561 1.0 1.0 5 Q15043,Q8NCH0 2 +Abnormality of exocrine pancreas physiology 0.5299283256130238 1.0806826837840828 0.2798382883782617 1.0 1.0 18 Q9UHX1,P09601 2 +Abnormal pelvis bone ossification 0.8132836636709306 1.0791924851745174 0.2805019289893722 1.0 1.0 3 Q96EX3 1 +Abnormal platelet volume 0.575333678704992 1.0741425073573392 0.2827588155115732 1.0 1.0 8 Q6PGP7,Q15477 2 +Paraparesis 0.4391873348248191 1.0714919515039585 0.2839482876905537 1.0 1.0 28 Q6DKK2,Q9Y619,P04062,Q13510 4 +Abnormality of the fetal cardiovascular system 0.6447044334975305 1.0701118915431582 0.2845689471198638 1.0 1.0 4 Q12768,P26196,P16435 3 +Personality changes 0.5463083719704417 1.0694932467394307 0.2848474702661452 1.0 1.0 15 P04062,Q9UI10,Q9UQN3,P00403 4 +Asymmetric septal hypertrophy 0.9707692307692286 1.067341912727812 0.2858174682679824 1.0 1.0 2 P15586 1 +Abnormal aortic valve physiology 0.4028449813553697 1.0520032861528912 0.2927980419499678 1.0 1.0 39 P31153,O00754,Q6ZXV5,Q9UHX1,P16278,Q6PGP7,Q15477,P01889,O75844,Q9NZ08,P04062,P46109,Q15056 13 +Minicore myopathy 0.80547860880271 1.0499012625957287 0.2937635110367136 1.0 1.0 3 P51114,Q15650 2 +Cirrhosis 0.4025690728966316 1.0496825168617334 0.2938641044886045 1.0 1.0 39 P11717,Q10567,Q10713,Q6PGP7,Q15477,Q15904,Q14108,P37287,Q14739,P04062 10 +Pedal edema 0.5697443802460106 1.0485395938170718 0.294390070179217 1.0 1.0 8 Q14108,P04062 2 +Hepatosplenomegaly 0.4062269089615377 1.0483870924405922 0.2944602980027135 1.0 1.0 41 P16278,Q13510,P10619,Q15833,Q14739,P04062,O00754 7 +Beaking of vertebral bodies 0.5696235745206553 1.0479864642131922 0.2946448432673993 1.0 1.0 8 Q6NUQ1,Q7RTS9,P16278,P04066 4 +Abnormal aortic valve cusp morphology 0.4762540758651751 1.047712145589115 0.2947712500142354 1.0 1.0 24 P31153,Q9UHX1,Q6PGP7,Q7Z5J4,Q15477,Q6DKJ4,P37268,P41227,Q15056,P61978 10 +Xerostomia 0.5516361585291222 1.0454734858552397 0.2958041886247375 1.0 1.0 13 Q9UQN3,P35637,Q14739,Q92804 4 +Orchitis 0.8033240997229932 1.0418329655938507 0.2974891274694824 1.0 1.0 3 Q9NZ08,P01889 2 +Pleuritis 0.8033240997229932 1.0418329655938507 0.2974891274694824 1.0 1.0 3 Q9NZ08,P01889 2 +Prominent sternum 0.636891466569811 1.0373775468837394 0.2995599382517238 1.0 1.0 4 Q7RTS9,P16278 2 +Global brain atrophy 0.5220900134567408 1.0371962921249278 0.2996443857584943 1.0 1.0 18 Q9UHX1,P35637,P07602,Q9H9P8,O75306 5 +Coronal craniosynostosis 0.5707342849079998 1.035068299158452 0.3006370159104437 1.0 1.0 6 P07237 1 +Visual loss 0.4233313955092378 1.0345766079377263 0.3008666829973681 1.0 1.0 51 Q10713,P00403,O60313,Q13509,O15460,P01889,P40939,P50897,O75503,O14773,P52732,P07602,O75306 13 +Follicular thyroid carcinoma 0.8012619193976324 1.034117820029147 0.3010810864641784 1.0 1.0 3 Q15437 1 +Agnosia 0.5656479155859367 1.0297899180293135 0.303108634506593 1.0 1.0 8 P05067 1 +Abnormal serum interleukin level 0.7990106374183554 1.025703701526158 0.3050312690731633 1.0 1.0 3 Q15833 1 +Preaxial hand polydactyly 0.5606182594046736 1.0184170215380288 0.3084798163976563 1.0 1.0 9 Q9UHX1 1 +Glioma 0.5402121651313923 1.0115543538986445 0.3117511802177808 1.0 1.0 14 P48735 1 +Bradykinesia 0.4510308928822495 1.0071001818403418 0.3138866338413495 1.0 1.0 26 P35270,Q6DKK2,Q96IX5,P04062,Q709C8,P02792 6 +Cardiorespiratory arrest 0.9529230769230776 1.006223916737887 0.3143078697713726 1.0 1.0 2 P13473 1 +Dyslexia 0.5619608655520667 1.0034707121280688 0.3156338011418937 1.0 1.0 7 Q9H6K4 1 +Thoracolumbar kyphosis 0.5968491200114246 1.0022378282238098 0.3162287417877545 1.0 1.0 5 P04062 1 +Abnormal greater sciatic notch morphology 0.6283530971438218 1.0017139187883135 0.3164817823138808 1.0 1.0 4 Q7RTS9 1 +Pleural effusion 0.5566459943533393 0.9999627715678312 0.3173285245796842 1.0 1.0 9 P49327,P01889,Q9NZ08,Q14739,P52732,P14174 6 +Glomerulopathy 0.5536003952762635 0.99927248047422 0.3176627127878051 1.0 1.0 10 P06280,Q14108,Q9NZ08 3 +Abnormal brain lactate level by mrs 0.5586859511845238 0.9979612974645048 0.3182981262262676 1.0 1.0 8 Q9BU61,P00403,O75306 3 +Mitral stenosis 0.6271389234069094 0.9966529311129702 0.3189330039916727 1.0 1.0 4 O75844 1 +Fatigable weakness of respiratory muscles 0.5457647712618265 0.9954683366331536 0.3195085366864307 1.0 1.0 12 P07737,Q9UQN3,P35637,Q9Y281,Q92804 5 +Hypoglycemic seizures 0.5594991780591878 0.9924010434469388 0.321001930165268 1.0 1.0 7 P00367,P40939 2 +Abnormal arterial physiology 0.4482547239543162 0.9880573212328396 0.323124576006492 1.0 1.0 26 P06280,P05067,O15460,P01889,O75844,Q9NZ08,Q9NWM8,Q14739 8 +Mild short stature 0.6245383919234064 0.985822697984383 0.3242201254316947 1.0 1.0 4 P10644,Q14739 2 +Progressive spasticity 0.5246546992532688 0.9849126294135828 0.3246669892446643 1.0 1.0 16 P17900,O43681,P07602 3 +Abnormal chorioretinal morphology 0.3934881885167323 0.9842583059960704 0.3249885241559735 1.0 1.0 31 P04439,Q10713,P50542,P41227,P40939,Q12768,Q99622,Q9Y5Y5,P52732,Q9Y619,O43505 11 +Angina pectoris 0.6239392857303423 0.9833295215017244 0.3254452850973379 1.0 1.0 4 O75844 1 +Micromelia 0.4659377304127611 0.9810364102983176 0.3265747866707844 1.0 1.0 24 O75874,Q9UHX1,O75718,P10644,P48735,Q15392,Q96EX3 7 +Subcutaneous hemorrhage 0.3882608009801792 0.9774276131071624 0.3283574981130495 1.0 1.0 36 P49327,P31153,P21964,P10644,Q86YV9,Q14108,Q15833,Q6UN15,Q9NWM8,P04062,P49257,O00192,Q8NCH0,Q13126 14 +Abnormal saccadic eye movements 0.4461670233121558 0.9737445352929398 0.3301833986152303 1.0 1.0 26 Q10713,Q8IV08,O14773,P04062,O75306 5 +Vitritis 0.7848515078117992 0.9730051970173595 0.3305507191633956 1.0 1.0 3 P06400 1 +Vascular calcification 0.5894573033967608 0.9705515859571336 0.3317716247333804 1.0 1.0 5 P04062 1 +Abnormal larynx morphology 0.3914860031656916 0.9679149413092168 0.3330868516517438 1.0 1.0 31 P07602,Q9UHX1,Q13510 3 +Acne 0.5265666019974404 0.9669935658380736 0.333547250147491 1.0 1.0 15 P49327,P21964,P01889,Q9NZ08,Q92542,O00192 6 +Fair hair 0.6199673740141172 0.9668189616661672 0.3336345436753252 1.0 1.0 4 P10644 1 +Woolly hair 0.5865945920670551 0.9583052326776812 0.3379088659843225 1.0 1.0 5 Q6PGP7 1 +High frequency sensorineural hearing impairment 0.5864269269843353 0.9575884479819144 0.3382703265975029 1.0 1.0 5 O75844,Q13510 2 +Progressive visual loss 0.4787790526371649 0.9555099130667484 0.3393198946935949 1.0 1.0 22 P50897,O75503,O14773 3 +Generalized hyperkeratosis 0.5850581372690205 0.9517387305519132 0.3412295018369287 1.0 1.0 5 O75844,P04066 2 +Macroglossia 0.378498431023228 0.9434534782364464 0.3454490002934003 1.0 1.0 33 Q10713,P16278,P04066,Q15437,Q05086,P10253,O00754,O75648 8 +Barrel shaped chest 0.5487630237954949 0.9378384366219203 0.348327444916674 1.0 1.0 6 Q32P28,Q14739,P04066 3 +Ureteral duplication 0.5454698002014129 0.9377069054332968 0.3483950541022653 1.0 1.0 8 O75844,P23786 2 +Morning myoclonic jerks 0.9313846153846104 0.933291836871225 0.3506693087526775 1.0 1.0 2 Q14108 1 +Nephropathy 0.4899807643005881 0.9328264326255152 0.3509095912600783 1.0 1.0 20 P06280,Q14108,Q96EX3,P00403 4 +Shoulder girdle muscle atrophy 0.6111453201970376 0.9302715395987224 0.3522305096032543 1.0 1.0 4 P06753,Q9H9S5,Q13049 3 +Abnormal ossification involving the femoral head and neck 0.6101779840802529 0.926275371130946 0.3543028918105351 1.0 1.0 4 Q14739 1 +Psoriasiform dermatitis 0.927076923076923 0.9188309633575026 0.3581839942471458 1.0 1.0 2 P10321 1 +Recurrent pharyngitis 0.9270769230769228 0.9188309633575026 0.3581839942471458 1.0 1.0 2 O15460 1 +Gastrointestinal infarctions 0.9270769230769228 0.9188309633575026 0.3581839942471458 1.0 1.0 2 O15460 1 +Glossitis 0.9270769230769228 0.9188309633575026 0.3581839942471458 1.0 1.0 2 O15460 1 +Mental deterioration 0.4839254853326891 0.918478379634705 0.358368472862228 1.0 1.0 94 O15118,O60313,Q9UQN3,P50897,P07602,Q9BQE5,P16278,Q13510,P06865,O75503,P02792,O75306,P61916,P00403,P17900,Q9Y487,Q14108,P04062,O95470,P54802,P04080,Q10713,P05067,O43681,P10644,P35637 26 +Spinal cord lesion 0.5361534065658806 0.9170949183704148 0.3590929036808292 1.0 1.0 10 O00400,Q93063,Q7Z5J4,Q04721 4 +Aortic regurgitation 0.4374565420870905 0.9141196099958268 0.3606539993793518 1.0 1.0 26 P31153,Q9UHX1,Q6ZXV5,Q6PGP7,Q15477,P01889,O75844,Q9NZ08,P46109,O00754 10 +Pathologic fracture 0.5055293021142805 0.9129014094781472 0.3612943961732973 1.0 1.0 17 O15269,Q14108,P04062,Q13126 4 +Premature loss of primary teeth 0.7675115033315516 0.9090666101891428 0.3633149662885215 1.0 1.0 3 P04080 1 +Iron accumulation in brain 0.6055730212804686 0.9072846507263216 0.3642562889716556 1.0 1.0 4 P02792 1 +Meningocele 0.5269053590573906 0.903458512797053 0.3662825973561752 1.0 1.0 12 Q8TAA9,Q10713,O00192 3 +Abnormality of extrapyramidal motor function 0.4463845652491944 0.9016156958820952 0.3672610502267717 1.0 1.0 73 P35270,P16278,P06865,P98175,P17900,Q6DKK2,Q9UQN3,P05067,Q9H6K4,P35610,Q96IX5,Q709C8,P02792,Q15056,P07602,Q9H9P8,P04062,P35637 18 +Retinal degeneration 0.4178877646044552 0.8998072023028847 0.3682228608418096 1.0 1.0 57 Q10713,Q13510,P50897,P51648,O75503,O14773,P04062,Q9H0F7 8 +Reduced forced vital capacity 0.5718301718769028 0.895408732687257 0.3705686341696541 1.0 1.0 5 O95817,Q9BQT8,Q9H9S5 3 +Hyperintensity of cerebral white matter on mri 0.4763879484315647 0.8952274930362836 0.3706654907740467 1.0 1.0 21 O75503,P07602,P17900 3 +Degeneration of the lateral corticospinal tracts 0.5385675430924448 0.8929702689731535 0.3718730944561224 1.0 1.0 6 O00400,P35637 2 +Hydrops fetalis 0.3929496274738424 0.890422881538754 0.3732388605323922 1.0 1.0 44 Q13510,P10619,P40939,P04062,Q96EX3 5 +Gingival bleeding 0.5271115323690561 0.8883260865868758 0.3743653713549697 1.0 1.0 11 Q14108,P04062 2 +Left ventricular hypertrophy 0.4426555132651946 0.8872277883833039 0.374956274348559 1.0 1.0 25 P06280,P10253,P40939,Q9H0F7 4 +Tongue fasciculations 0.5260001317062821 0.8830301573635538 0.3772199777884268 1.0 1.0 11 P51114,Q9NQT5,Q13510 3 +Macrogyria 0.5359896103180914 0.8816581787663694 0.377961683257912 1.0 1.0 6 Q15392 1 +Abnormal neuron morphology 0.4416608418606595 0.8806478729621227 0.3785084387206743 1.0 1.0 25 Q13510,Q9UQN3,Q92734,P35637,Q92804 5 +Tritanomaly 0.7589969295306287 0.8779522830613627 0.3799696143431863 1.0 1.0 3 Q9H6K4 1 +Anomalous trichromacy 0.7589969295306287 0.8779522830613627 0.3799696143431863 1.0 1.0 3 Q9H6K4 1 +Bloody diarrhea 0.7588056202451898 0.8772555368175243 0.380347856874351 1.0 1.0 3 Q6PGP7 1 +Fatigable weakness of swallowing muscles 0.5246626315381693 0.8766606716588156 0.380670974247475 1.0 1.0 11 Q9UQN3,P07737,P35637,Q92804 4 +Hyperconvex nail 0.5316862198694252 0.8751851536795675 0.3814731698979055 1.0 1.0 8 Q9Y619 1 +Bone cyst 0.7580794090489401 0.8746116538064851 0.3817852446505654 1.0 1.0 3 P21912,Q15437 2 +Rhizomelia 0.5207378908316976 0.8735176676493629 0.3823809805514084 1.0 1.0 12 Q9Y366,O75718,O00116,Q7RTS9,Q15392,Q14739 6 +Poor eye contact 0.3834190590737503 0.8732180112011442 0.3825442594218962 1.0 1.0 40 Q15907,Q9UHX1,O75380,O43676,Q8N183,Q9P0J0,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 11 +Aortic valve stenosis 0.5290211891994974 0.8722743763430596 0.38305871281664 1.0 1.0 9 O75844,P04062 2 +Neoplasm of fatty tissue 0.5284580572049685 0.8696870400297496 0.3844714566281211 1.0 1.0 9 Q8TAA9,Q15437 2 +Keratoconjunctivitis 0.5295060530649438 0.8653334686835059 0.386855786094525 1.0 1.0 8 Q9NZ08,Q14739,P01889 3 +Crumpled long bones 0.910461538461538 0.8634993626813446 0.3878629696861946 1.0 1.0 2 O75718 1 +Vertebral arch anomaly 0.7532049876727085 0.8569061365684566 0.3914967610881192 1.0 1.0 3 P10644 1 +Narrow vertebral interpedicular distance 0.7532049876727085 0.8569061365684566 0.3914967610881192 1.0 1.0 3 P10644 1 +Abnormality of the alveolar ridges 0.5621429510888899 0.8544254575522052 0.3928692954363582 1.0 1.0 5 P98175,Q15392 2 +Corneal neovascularization 0.5297525418305572 0.8543522269561469 0.39290985744225 1.0 1.0 6 O00192,P21964 2 +Diabetes insipidus 0.5091382015103227 0.8542379930343096 0.3929731360215185 1.0 1.0 14 P06280,O15460,Q9H0F7 3 +Abnormal posterior segment imaging 0.562000254671895 0.8538236906550778 0.3932026859129771 1.0 1.0 5 Q8WWY3,Q9H0F7 2 +Aplasia hypoplasia involving the carpal bones 0.5619680719144514 0.85368798050694 0.3932778956332403 1.0 1.0 5 Q9Y5S9,Q7RTS9 2 +Carpal bone hypoplasia 0.5619680719144514 0.85368798050694 0.3932778956332403 1.0 1.0 5 Q9Y5S9,Q7RTS9 2 +Tissue ischemia 0.4825242242188683 0.8523414135407351 0.3940246267986222 1.0 1.0 19 P06280,P05067,O15460,O75844,Q9NZ08 5 +Symptomatic seizures 0.5246214226532331 0.8520803682913377 0.3941694872256915 1.0 1.0 9 P00367,P40939 2 +Prenatal maternal abnormality 0.5126195824821973 0.8516055145106778 0.394433077886561 1.0 1.0 13 P31153,P49366,Q8TAA9,P40939,Q14739,O43772 6 +Respiratory distress 0.3933674094541891 0.8479898484695703 0.3964436242920484 1.0 1.0 47 Q9UHX1,Q13510,P23786,P10253,Q969X5,P04062,P07602,Q9Y619,O75306,P62857,O75648 11 +Thickened cortex of long bones 0.7499492040926372 0.8451206097229683 0.3980435023646342 1.0 1.0 3 O00754 1 +Bell shaped thorax 0.5597831338650598 0.8444815279403738 0.3984003813154737 1.0 1.0 5 Q8WVQ1,Q96EX3 2 +Airway obstruction 0.5005816293632853 0.8330734122014223 0.4048033275056957 1.0 1.0 15 P06280,P21964,O75844,P09601,O00192 5 +Velopharyngeal insufficiency 0.5247841027883015 0.8326697360218551 0.4050310172966669 1.0 1.0 6 Q96DF8 1 +Hyperacusis 0.5219727578271234 0.8313848998244178 0.4057562266770556 1.0 1.0 8 P17900,Q7Z5J4 2 +Sound sensitivity 0.5219727578271234 0.8313848998244178 0.4057562266770556 1.0 1.0 8 P17900,Q7Z5J4 2 +Abnormal retinal vascular morphology 0.3985781027328166 0.8307345344733343 0.4061236125787042 1.0 1.0 51 P16278,Q13510,P17900,P10619,Q9H0F7,P07602,O75306 7 +Abnormality of the phalanges of the hallux 0.5868312658509258 0.8306281663907638 0.4061837179043264 1.0 1.0 4 Q6DKJ4 1 +Bruising susceptibility 0.4051321579065591 0.8227984837451234 0.4106225990766852 1.0 1.0 28 P49327,P31153,P10644,Q86YV9,Q14108,Q15833,Q6UN15,Q9NWM8,P04062,P49257,Q8NCH0,Q13126 12 +Uncombable hair 0.897846153846146 0.8220099534481915 0.4110712320485026 1.0 1.0 2 Q6PGP7 1 +Weak cry 0.517686501027405 0.8203554056661385 0.4120135296224556 1.0 1.0 9 Q15650,Q13510 2 +Hemivertebrae 0.5093585777352716 0.818532587620188 0.4130531421255476 1.0 1.0 12 Q9Y619 1 +Poor wound healing 0.5208560019966857 0.8155751801483088 0.4147431497358846 1.0 1.0 6 P04062 1 +Abnormality of the gastric mucosa 0.5014302317128069 0.815564290262262 0.4147493802953073 1.0 1.0 14 Q6PGP7,Q15477,P04062,Q14739 4 +Anorexia 0.4132321361240038 0.8118133910635533 0.4168987169935974 1.0 1.0 27 P06280,P10644,O15460,P01889,Q14108,Q9NZ08,P04062 7 +External ophthalmoplegia 0.4913077485729257 0.8094691683032473 0.4182453303667701 1.0 1.0 16 P00403,Q8N183,O60313,Q13509,P50570 5 +Syringomyelia 0.5178668581875756 0.8067911142393858 0.4197868393813908 1.0 1.0 7 Q93063,Q7Z5J4 2 +Vascular neoplasm 0.3658917827247853 0.805165348153433 0.4207242698378968 1.0 1.0 35 O75874,P10619,P48735 3 +Hepatic failure 0.3953844567234378 0.804611546617206 0.421043876903469 1.0 1.0 51 Q9Y619,Q10713,O15118,Q13510,Q6PGP7,O15460,P23786,P01889,P40939,P04062,O43772 11 +Megaloblastic anemia 0.5158489342752404 0.80390550364398 0.421451551319794 1.0 1.0 8 P41440 1 +Soft skin 0.5154394502127568 0.802072122658066 0.4225112396917005 1.0 1.0 8 Q9NWM8,Q13126 2 +Abnormal tongue physiology 0.4790373390627295 0.8000775447911865 0.4236658704184521 1.0 1.0 18 Q13510,Q9BQT8,P51114,P10253,Q9NQT5 5 +Hyperlipidemia 0.3611957542312551 0.7974097414619624 0.4252131035307744 1.0 1.0 33 P06280,P28070,Q7Z5J4,P23786,Q15833,O75844,O95470 7 +Equinovarus deformity 0.5484316903394647 0.7968936284464385 0.4255128116312974 1.0 1.0 5 P40939 1 +Hypoventilation 0.5010236234483995 0.7946543671213693 0.4268145837297128 1.0 1.0 13 O75380,Q8N183,Q9BU61,O75306,P61978 5 +Ileus 0.5773631794650027 0.7923536486474656 0.4281544981071965 1.0 1.0 4 P50336 1 +Temporal pattern 0.5145872693708892 0.792350879439581 0.4281561123385629 1.0 1.0 7 O60313,P04062,P12694 3 +Molar tooth sign on mri 0.5472878130636369 0.7921225063820724 0.428289248139464 1.0 1.0 5 O15078,Q10713,P36405 3 +Bacterial endocarditis 0.8886153846153753 0.7919690690884789 0.4283787117856437 1.0 1.0 2 P04062 1 +Cerebral calcification 0.380415052283896 0.790595783572302 0.4291799081080052 1.0 1.0 30 P05067,P23786,O00584 3 +Orthostatic hypotension 0.4964283990442908 0.7905713448060606 0.4291941739514997 1.0 1.0 14 P07602 1 +Abnormal left ventricle morphology 0.3906454978318698 0.7897689254661249 0.4296627299187312 1.0 1.0 29 P06280,P10253,P40939,Q9H0F7 4 +Diaphragmatic eventration 0.7343798091720553 0.7892482880063708 0.4299669041504796 1.0 1.0 3 Q15650,P08243 2 +Nonprogressive 0.5145893509901271 0.7883992964414335 0.4304631822228408 1.0 1.0 6 Q69YN2,Q9BUF5,Q10713,Q06210 4 +Type ii lissencephaly 0.7336485448438064 0.7866451885105274 0.4314895984907494 1.0 1.0 3 Q13509 1 +Young adult onset 0.5078991913535826 0.7853957216946117 0.4322215884057958 1.0 1.0 10 P07602 1 +Eeg with spike wave complexes 0.4945316954518599 0.781117405198541 0.4347334459092411 1.0 1.0 14 O75503,Q14108 2 +Hypotension 0.4425409833427933 0.7807275052369232 0.4349627797821125 1.0 1.0 23 P49366,O43681,P04062,P07602,O43772 5 +Abnormal mitral valve physiology 0.3702031995075558 0.7787230622733947 0.436142867792942 1.0 1.0 39 P06280,O00754,P01889,P40939,O75844,Q9NZ08,P04062,Q15056,O75306 9 +Breast carcinoma 0.4255749993311032 0.7747530850866238 0.4384855762436119 1.0 1.0 25 O75874,P48735 2 +Keratitis 0.507590538611452 0.774433067632538 0.438674735061219 1.0 1.0 9 Q9NZ08,Q14739,P01889 3 +Cutaneous photosensitivity 0.4414289815680014 0.7738590194585443 0.4390141661382079 1.0 1.0 23 Q06136,P04080,Q14108,P50336 4 +Abnormality of the tarsal bones 0.3671927320691299 0.7706871562421498 0.4408923866601333 1.0 1.0 31 Q7RTS9,Q93063,Q9UHX1,P98175,P40939,O75844,Q969X5,Q14739,Q9UPT5 9 +Restlessness 0.3692222980257955 0.7705859836886632 0.440952371735966 1.0 1.0 39 P42892,P05067,Q9UQN3,P10644,Q709C8,Q92804,P04062,P52732,P35637 9 +Abnormal mitochondria in muscle tissue 0.4481111885570498 0.7696774333459919 0.441491259601932 1.0 1.0 22 O75380,P00403,O43676,Q8N183,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 9 +Hand polydactyly 0.3671545476115998 0.7688623493993421 0.4419750306062255 1.0 1.0 38 Q9UHX1,Q10713,P98175,Q7Z5J4,Q14739,Q9H0F7,O00192,Q96EX3,Q15067 9 +Delayed ability to stand 0.571396563098464 0.7684141185855817 0.4422411951187055 1.0 1.0 4 P10253 1 +Abnormality of chromosome segregation 0.5098315965650106 0.7678524220160916 0.4425748663175961 1.0 1.0 6 Q15437,Q7Z5J4,Q14739 3 +Cns demyelination 0.4938646007729418 0.7597250380812265 0.4474189591075794 1.0 1.0 13 P51648,Q9H9P8,Q9UI10,P07602 4 +Sleep wake cycle disturbance 0.5067475313864801 0.7579785070031134 0.4484638496822699 1.0 1.0 7 Q7Z5J4 1 +Disproportionate short stature 0.385890579515558 0.754239498361982 0.4507054241200419 1.0 1.0 29 Q9UHX1,O75718,Q9Y366,P16278,P10644,Q6DKJ4,Q15392,Q14739,Q32P28,Q96EX3 10 +Macrovesicular hepatic steatosis 0.505218188970515 0.7512991026588358 0.4524726691372569 1.0 1.0 7 P23786 1 +Focal t2 hyperintense brainstem lesion 0.4642825517828168 0.7505565823070072 0.4529195591935122 1.0 1.0 19 O75380,O43676,Q8N183,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 8 +Tachycardia 0.4132519351902611 0.7497579674884082 0.4534004880816047 1.0 1.0 26 P42892,O43772,P23786,P0DP25 4 +Fatigable weakness of bulbar muscles 0.4949393226811081 0.7494586624464042 0.4535808049338217 1.0 1.0 12 P07737,P50995,P06753,Q9UQN3,Q92804,P35637 6 +Juvenile onset 0.3719876971727888 0.7475915373201149 0.4547065707766062 1.0 1.0 42 P06280,P54802,P04080,Q93063,P16278,O15118,Q13510,Q9UI10,P49770,O14773,P41440 11 +Cholecystitis 0.5012229053199129 0.745653920174981 0.4558765017746116 1.0 1.0 9 P07602 1 +Flaring of rib cage 0.7220306298279322 0.7455662493639326 0.4559294773234625 1.0 1.0 3 P16278 1 +Thoracic kyphosis 0.4833344141033633 0.7452848844656474 0.4560995169326811 1.0 1.0 15 O00754,P51648,Q9UHX1,P04062 4 +Epiphyseal dysplasia 0.5044751158536955 0.7448164556415616 0.4563826855553372 1.0 1.0 6 Q7RTS9,Q9HC07 2 +Echolalia 0.4990462635783939 0.744642736210483 0.4564877253309725 1.0 1.0 10 Q9UQN3,Q9UHX1 2 +Neoplasm of the adrenal gland 0.4870736381698527 0.7440805726879423 0.456827731675606 1.0 1.0 14 P48735 1 +Porokeratosis 0.7214527546937544 0.7435371748065918 0.4571565234413905 1.0 1.0 3 P14324,Q15126 2 +Vertical supranuclear gaze palsy 0.4900013970095754 0.7409605791355179 0.4587173426946132 1.0 1.0 13 O15118,P02792 2 +Severe short stature 0.4358742126181302 0.7396424647734202 0.4595169677392983 1.0 1.0 23 P10619,Q9Y619,P16278,Q15392 4 +Atrophic scars 0.5027856040270717 0.7375731456902722 0.4607738791233082 1.0 1.0 6 Q8NCH0,Q9NWM8 2 +Abnormal pleura morphology 0.4550174393972324 0.7322867792139228 0.4639935470645855 1.0 1.0 20 P49327,P31153,Q93063,Q92917,O15460,P01889,Q9NZ08,Q8NCH0,Q14739,P52732,P14174 11 +Proximal tubulopathy 0.4270780544154031 0.7322842105686082 0.4639951145399381 1.0 1.0 24 O75380,P00403,O43676,Q8N183,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 9 +Alveolar ridge overgrowth 0.8698461538461433 0.7318063637676248 0.4642867643123325 1.0 1.0 2 Q15392 1 +Bone marrow foam cells 0.7177609087294777 0.7306074100845441 0.465018984585555 1.0 1.0 3 O15118 1 +Hypokinesia 0.4842783451897156 0.7302598677496689 0.4652313542548285 1.0 1.0 14 P04062 1 +Joint stiffness 0.3967994373640302 0.7288409948062948 0.4660989317381891 1.0 1.0 57 P15586,O75874,P54802,Q8TAA9,P16278,O15460,P48735,P51648,O75844 9 +Increased serum pyruvate 0.3567111718683762 0.7285741712094629 0.4662621827603119 1.0 1.0 35 Q70HW3,O75380,O43676,Q8N183,P22695,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 10 +Vertebral wedging 0.7171437365343207 0.7284516189158121 0.4663371747237597 1.0 1.0 3 Q8WVQ1,Q96AY3 2 +Antineutrophil antibody positivity 0.7169402160287675 0.7277410816977713 0.4667720972083464 1.0 1.0 3 P49327 1 +Impaired t cell function 0.4924356453289024 0.7248143318989678 0.4685659421865495 1.0 1.0 11 Q96DF8,O00192,P21964 3 +Cough 0.4329742752191883 0.7218461257208166 0.4703890870416867 1.0 1.0 23 P10644,O15460,P01889,Q92734,P35610,P04062,P41440 7 +Abnormal thoracic spine morphology 0.3815211522059509 0.7217222303242352 0.4704652716979365 1.0 1.0 29 Q9UHX1,Q13509,O75844,P51648,P04062 5 +Decreased facial expression 0.371437460496162 0.7211244705024201 0.4708329365710861 1.0 1.0 30 P35270,Q05086,Q969X5,P04062,P02792 5 +Bilateral sensorineural hearing impairment 0.4252139361064379 0.7205171802194209 0.4712066256871534 1.0 1.0 24 P07602,O43681,Q13509,P00403 4 +Abnormality of the autonomic nervous system 0.3990111426989494 0.7181871125214203 0.4726419231300975 1.0 1.0 59 P06280,O15269,Q10713,P42892,O43681,Q13509,P50336,P0DP25,Q709C8,Q9H0F7,P41440,P07602,Q96EK5,P04062,O00192,Q15067 16 +Fibrous tissue neoplasm 0.4736112955624059 0.7177979787058949 0.4728818598639792 1.0 1.0 16 P10644,Q15437,Q15392,P21912,Q13126 5 +Abnormal circulating glutamine family amino acid concentration 0.4972448423251357 0.7166250947389319 0.4736054559534102 1.0 1.0 7 O96000 1 +Cardiac valve calcification 0.5574787798482383 0.7131839249070042 0.4757319521731928 1.0 1.0 4 O75844 1 +Mitral valve calcification 0.5574787798482383 0.7131839249070042 0.4757319521731928 1.0 1.0 4 O75844 1 +Spastic paraparesis 0.4452623082416913 0.7126519517282129 0.4760611555480472 1.0 1.0 21 Q6DKK2,Q9Y619,P04062 3 +Abnormal cardiac test 0.4673769610077553 0.7096264850829781 0.4779357911732937 1.0 1.0 17 P10253,P40939 2 +Vaginal atresia 0.711109903338448 0.7074640236507802 0.479278162217635 1.0 1.0 3 Q9H0F7 1 +Abnormality of immune serum protein physiology 0.4949160776744673 0.7065482152441112 0.4798472797561852 1.0 1.0 7 Q15833,P42224 2 +Abnormality of thalamus morphology 0.4712612602181096 0.7057314420778715 0.4803551638798906 1.0 1.0 16 Q9UPT5,Q13509,O75306,P02792 4 +Atlantoaxial instability 0.8615384615384629 0.7056086359272074 0.4804315522641686 1.0 1.0 2 Q9NWM8 1 +Abnormality of the glenoid fossa 0.861538461538448 0.7056086359271616 0.4804315522641971 1.0 1.0 2 Q9Y619 1 +Resting tremor 0.4438079485973943 0.7042320273534477 0.4812882888202008 1.0 1.0 21 P07602,P04062,P02792 3 +Abnormal delivery 0.4299786113441312 0.7035148957628269 0.4817349271068107 1.0 1.0 23 O75718,Q9Y487,O75844,Q969X5,Q9Y619 5 +Abnormal globus pallidus morphology 0.4931091723558204 0.7030124404614313 0.4820479966761573 1.0 1.0 8 O75306 1 +Subcapsular cataract 0.4940751375370804 0.7004154642788097 0.4836678814683179 1.0 1.0 6 Q9H6K4 1 +Migraine 0.436353817584382 0.6994685733692346 0.4842592462791555 1.0 1.0 22 P49327,P00403,O60313,P05067,P01889,O00170,Q9NZ08,P60866 8 +Amyotrophic lateral sclerosis 0.4813389265562692 0.6991265937040175 0.4844729202529856 1.0 1.0 13 Q9UQN3,P35637,Q92804 3 +Anarthria 0.4937471838853313 0.6990228725067318 0.4845377368961889 1.0 1.0 6 P02792 1 +Eeg with polyspike wave complexes 0.4924645711466813 0.6959663853931773 0.4864498812739586 1.0 1.0 7 Q14108 1 +Underdeveloped supraorbital ridges 0.4772862777651535 0.6958498986588704 0.4865228362127634 1.0 1.0 14 Q6PGP7,P16435,P98175,Q9Y5Y5,P52732,P50542 6 +Rhabdomyolysis 0.4730654979178265 0.6936164759046494 0.4879227584849386 1.0 1.0 15 O43772,P23786,P40939 3 +Aspiration pneumonia 0.4281894356040889 0.6925934425920948 0.488564726647505 1.0 1.0 23 P04062,Q13510 2 +Paroxysmal involuntary eye movements 0.4414686082112137 0.6907151375713161 0.4897445745425455 1.0 1.0 21 O75380,O43676,Q8N183,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 8 +Fetal distress 0.4039782387128871 0.6875974207031733 0.4917063329291469 1.0 1.0 26 O75380,O43676,Q8N183,Q9NVI7,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 9 +Coarse hair 0.4522333549889416 0.6841590337749706 0.4938747476569078 1.0 1.0 19 P15586,P54802 2 +Papule 0.4521415250437179 0.6836561215568355 0.4941923371010814 1.0 1.0 19 O75844,Q9NZ08,P01889 3 +Disproportionate short trunk short stature 0.4892321806126936 0.6820565504023524 0.4952031933748977 1.0 1.0 7 Q9UHX1,P16278 2 +Communicating hydrocephalus 0.5201797402608948 0.6806241371041639 0.4961093500226354 1.0 1.0 5 P07237 1 +Nocturnal hypoventilation 0.7032933210218554 0.6805249067268968 0.4961721567377957 1.0 1.0 3 Q9Y281,P61978 2 +Ambiguous genitalia 0.4325647576774656 0.6770162694198881 0.4983956318672689 1.0 1.0 22 Q15392,Q96EX3 2 +Gastrointestinal inflammation 0.4449867372819293 0.6757490002609547 0.4992000196521835 1.0 1.0 20 Q15833,Q6PGP7,P08183,P01889 4 +Retinal thinning 0.8516923076922973 0.6749342908330224 0.4997175131615283 1.0 1.0 2 P51648 1 +Abnormal serum interferon level 0.4879888486524512 0.6746525766515492 0.4998965208169288 1.0 1.0 6 Q15833 1 +Abnormality of the vasculature of the eye 0.4194489004503383 0.6745273666347155 0.499976093057398 1.0 1.0 74 P06280,Q10567,P28070,P04066,Q9H0F7,P07602,Q96DF8,P16278,P06865,Q13510,P10619,Q14739,Q15056,O75306,P17900,Q9NZ08,O00192,Q8WWY3,P01889,O00462 20 +Eyelid myoclonus 0.4813526598291459 0.673544824519985 0.5006007418150626 1.0 1.0 11 Q01105,P00374,Q13510 3 +Abnormal corneal epithelium morphology 0.4727260680656743 0.6735420840783128 0.5006024846226287 1.0 1.0 14 P01889,P51648,O75844,Q9NZ08,Q14739,Q96EK5 6 +Abnormal acetabulum morphology 0.4319547800284741 0.6734106704957938 0.5006860620018512 1.0 1.0 22 Q6NUQ1,O75718,Q7RTS9,Q9Y366,P16278,Q96AY3,Q8WVQ1,Q969X5,Q9Y584 9 +Petechiae 0.4828734256679214 0.6710520251349111 0.5021873876487573 1.0 1.0 10 Q15833,P04062 2 +Aplasia hypoplasia of the sternum 0.5465865322329637 0.6706326902466586 0.5024545519328871 1.0 1.0 4 Q9Y619 1 +Abnormality of small intestinal villus morphology 0.4861925208353435 0.667082877348259 0.504719196646155 1.0 1.0 6 Q6PGP7,Q15477 2 +Abnormal pharynx morphology 0.3529040072770376 0.6664718309216787 0.5051095629580602 1.0 1.0 37 P15586,P54802,Q7RTS9,P16278,Q13510,Q03518,Q86YV9,O15460,P01889,Q15833,P13051 11 +Muscle fibrillation 0.4675553371674217 0.6661168244741232 0.5053364314525794 1.0 1.0 15 Q13510,Q9BQT8,Q92734,P51114,Q9NQT5 5 +Postaxial hand polydactyly 0.4590090618145546 0.6658959947825082 0.5054775807469651 1.0 1.0 17 Q10713,Q96EX3,Q9H0F7 3 +Ragged red muscle fibers 0.4539502297006245 0.6648171401486165 0.5061674583345694 1.0 1.0 18 Q9H2D1,Q70HW3,P00403 3 +Epistaxis 0.4672405964189349 0.6645512296535211 0.5063375718378194 1.0 1.0 15 P04062,P10644,O15460,P01889 4 +Immune dysregulation 0.8479999999999912 0.6635416812525359 0.5069836937200833 1.0 1.0 2 Q15833 1 +Decreased serum iron 0.8476923076923104 0.6625950986269087 0.5075899101360462 1.0 1.0 2 Q15477 1 +Abnormal brainstem mri signal intensity 0.4300884530273395 0.6623946635412093 0.5077183228423241 1.0 1.0 22 O75380,O43676,Q8N183,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 8 +Cervical myelopathy 0.6969686472737564 0.658945654894545 0.5099306670468009 1.0 1.0 3 P16278 1 +Spondyloepimetaphyseal dysplasia 0.4826911227032914 0.652375002845299 0.514159286047573 1.0 1.0 6 Q7RTS9,Q96HY6,Q9NR45 3 +Eeg with generalized slow activity 0.4800844543258983 0.6513756945750776 0.514803996431086 1.0 1.0 9 O75503 1 +Follicular hyperkeratosis 0.4822905148378099 0.6506962805074457 0.5152425646921688 1.0 1.0 6 Q9NWM8 1 +Open mouth 0.3620439337021181 0.6491236968113754 0.5162584261954319 1.0 1.0 30 Q96DF8,Q10713,P10644,Q86XL3,P04062 5 +Absent hypoplastic paranasal sinuses 0.6938416036693296 0.6483520294515004 0.5167572893414372 1.0 1.0 3 P04066 1 +Osteochondroma 0.8415384615384639 0.6437560368311358 0.5197336460812323 1.0 1.0 2 P10644 1 +Horizontal nystagmus 0.405327813432826 0.6434606283997397 0.5199252540996253 1.0 1.0 25 P07602,O14773,Q9H061 3 +Atelectasis 0.4747355758984742 0.643236461584311 0.5200706776406694 1.0 1.0 11 O00192,Q13510 2 +Hemiparesis 0.4723252750191201 0.642946563855575 0.5202587738341995 1.0 1.0 12 Q9NZ08,P00403,P01889 3 +Lewy bodies 0.4798751131387961 0.6420842114674051 0.5208185066793001 1.0 1.0 7 P04062 1 +Increased circulating lactate dehydrogenase concentration 0.4540987139743472 0.6404294988363601 0.5218934100394077 1.0 1.0 17 P06400,P23786,P37287,Q96RL7,P10253,P41440 6 +Supernumerary tooth 0.4798307578550127 0.6404076144400462 0.5219076338102684 1.0 1.0 6 Q9UHX1 1 +Abnormality of the wrist 0.3422951838372258 0.6401389909281865 0.5220822419933013 1.0 1.0 33 Q7RTS9,Q93063,P16278,Q13510,Q9Y5S9,P16435,Q13509,Q6DKJ4,Q8WVQ1,O75844,Q9H6K4,Q969X5,Q04721 13 +Protrusio acetabuli 0.6909255002070144 0.6385196031624395 0.5231354974083664 1.0 1.0 3 O75718 1 +Mask like facies 0.4678664736234469 0.6348316573191495 0.5255382139805476 1.0 1.0 13 O75787,Q9GZZ9,Q9H9S5,P38606,Q05086,P04062,Q13049 7 +Abnormality of the foot musculature 0.8378461538461528 0.6325391746373303 0.5270346185602095 1.0 1.0 2 O14979 1 +Cardiomegaly 0.3469055027792412 0.6324422742481597 0.5270979175850687 1.0 1.0 36 P54802,P04066,P23786,P04062,P13473 5 +Middle age onset 0.4697561289107302 0.6310193094460952 0.5280278989634826 1.0 1.0 12 P07602,P02792 2 +Vestibular dysfunction 0.3496566903871292 0.6306738309175477 0.5282538131998287 1.0 1.0 31 P06280,P49327,P10644,O15460,Q02978,P01889,O00170,Q6UN15,Q9NZ08,P0DP25,P41440,Q15043,P21912 13 +Platybasia 0.4770916819601476 0.6302840356696939 0.5285087659913255 1.0 1.0 7 O00192,P21964 2 +Abnormal protein glycosylation 0.4474319837435988 0.6302531506519096 0.5285289695872077 1.0 1.0 18 Q8N511,Q15904 2 +Conjunctival hamartoma 0.8344615384615305 0.62231575469555 0.5337342636690807 1.0 1.0 2 Q15437 1 +Diffuse cerebral atrophy 0.4453929328844417 0.619500416889549 0.5355867473620703 1.0 1.0 18 P07602,P16278 2 +Abnormality of the calcaneus 0.4730982019296024 0.6161654194656278 0.5377853489367146 1.0 1.0 8 Q14739,P40939 2 +Axonal degeneration 0.473056831283803 0.6159881668625559 0.5379023296631829 1.0 1.0 8 Q6DKK2,Q9BQT8,Q92734 3 +Broad ribs 0.5040268264183896 0.6159211620187904 0.5379465539221839 1.0 1.0 5 P16278 1 +Episodic tachypnea 0.473568909927323 0.6154130844740625 0.5382819525373186 1.0 1.0 7 Q10713 1 +Scarring 0.3759737182749001 0.6141238537231036 0.5391334865735393 1.0 1.0 28 Q8WWY3,P04439,P53634,P50336,Q9NWM8,Q92542,Q9H0F7,Q8NCH0 8 +Genu varum 0.4603242234869236 0.6134849094422787 0.5395557578659307 1.0 1.0 14 Q7RTS9,Q9Y619,Q9Y5S9,Q8WVQ1,Q99622,Q9Y281 6 +Abnormal superior cerebellar peduncle morphology 0.6832871652816279 0.6129858779228148 0.5398856774947824 1.0 1.0 3 O15078,Q10713 2 +Branchial anomaly 0.4718102204534541 0.6106519350638131 0.5414300325291901 1.0 1.0 8 Q9UHX1,P46109 2 +Ventricular preexcitation 0.4726702008736991 0.6106486508445172 0.5414322072291893 1.0 1.0 6 P10253,O75306,P13473 3 +Slow saccadic eye movements 0.4693617494318002 0.6106077703350319 0.5414592772981277 1.0 1.0 10 P04062 1 +Akinesia 0.467260665273268 0.6093062637616083 0.5423214560317717 1.0 1.0 11 P04062,Q709C8 2 +Increased c peptide level 0.8295384615384462 0.6075481682001622 0.5434871864785729 1.0 1.0 2 P40939 1 +Neurodegeneration 0.3996981559823812 0.6075071824577047 0.5435143775311673 1.0 1.0 25 P17900,Q6DKK2,Q9UQN3,Q92804,P02792 5 +Transient ischemic attack 0.471190951748729 0.6054165316818862 0.5449022693707541 1.0 1.0 7 O75844 1 +Cessation of head growth 0.4709622546874227 0.6044569445240081 0.5455398862132372 1.0 1.0 7 Q05086,Q9UI10 2 +Inflammatory abnormality of the eye 0.3431786777154125 0.6020638561112852 0.5471316324805922 1.0 1.0 36 P04080,Q10567,P28070,P01889,P51648,Q9NZ08,Q14739,Q9UDY8 8 +Aspiration 0.4651608365016412 0.5998379582614842 0.5486142333375743 1.0 1.0 11 P17900 1 +Abnormal fundus autofluorescence imaging 0.679252129315746 0.5996314711266209 0.548751868425406 1.0 1.0 3 Q9H0F7 1 +Abnormal gallbladder morphology 0.3456527635427005 0.5991482243603361 0.5490740457117691 1.0 1.0 31 O43681,Q15437,P04062,Q15056,P07602 5 +Hypocalcemia 0.4457101326211913 0.5973002686144899 0.5503069251711261 1.0 1.0 17 Q96DF8,Q4J6C6,P10644,P40939,O00192 5 +Perimembranous ventricular septal defect 0.4691562650937972 0.5968906332195394 0.5505804013819511 1.0 1.0 7 Q9UHX1 1 +Hypohidrosis 0.4660900057287896 0.5961374629568759 0.5510833990037334 1.0 1.0 10 P06280,P04080 2 +Basal ganglia calcification 0.469102052598089 0.5959325282234111 0.5512203018254156 1.0 1.0 6 P00403 1 +Anterior uveitis 0.6768236380424775 0.5916404036715 0.5540914121014584 1.0 1.0 3 P14174,P01889 2 +Hepatitis 0.4523725539147382 0.591308023318902 0.5543140546858911 1.0 1.0 15 P49327,P11717,Q15477,P42224,Q9Y619,Q13043 6 +Short nail 0.4970655439889173 0.5885222789370963 0.556181784357549 1.0 1.0 5 O75844 1 +Submucous cleft of soft and hard palate 0.423327802895825 0.5871833886514117 0.5570805474948273 1.0 1.0 21 O75844,Q9Y619,Q15392 3 +Ecchymosis 0.4575508631405819 0.5863495798296047 0.5576406194800345 1.0 1.0 13 Q15833,Q8NCH0,P04062 3 +Abnormal blistering of the skin 0.4283636116337448 0.5835298401010764 0.5595366751839692 1.0 1.0 20 Q06136,Q9NZ08,P50336 3 +Abnormal lumbar spine morphology 0.4643684967780047 0.5828363612768487 0.5600034645288696 1.0 1.0 9 P04062 1 +Aplasia hypoplasia involving the sinuses 0.4953908279303506 0.5819785383799347 0.5605811370135745 1.0 1.0 5 P04066 1 +Red green dyschromatopsia 0.6738234677235766 0.5818173813841884 0.5606896950629827 1.0 1.0 3 Q9H6K4 1 +Optic disc coloboma 0.5230787362711985 0.5811960223306557 0.5611083481889687 1.0 1.0 4 Q10713,P78318 2 +Abnormal exteroceptive sensation 0.367641844731156 0.5811083694917699 0.5611674182201662 1.0 1.0 51 P06280,P54802,P05067,O15460,Q9H6K4,Q9NZ08,P07602,Q8NCH0 8 +Broad palm 0.4647378861783506 0.5805633152671873 0.5615348026474525 1.0 1.0 8 P10644,Q7Z5J4,Q14739 3 +Hepatoblastoma 0.4646643881766033 0.5802523368092454 0.5617444644283347 1.0 1.0 8 Q6PGP7 1 +Hyperextensible skin 0.453198470542592 0.5794344977573735 0.5622960323525106 1.0 1.0 14 Q9UHX1,Q8NCH0,P04062 3 +Abnormal aortic arch morphology 0.4527173594635689 0.5771487332513838 0.5638389858735948 1.0 1.0 14 Q96DF8,Q9UHX1,P21964,O00459,P30153,O00192 6 +Abnormal morphology of the abdominal musculature 0.4600350446647634 0.5768498822050065 0.564040869176268 1.0 1.0 11 O00462 1 +Generalized muscle weakness 0.3521728394047766 0.574448419794215 0.56566439530057 1.0 1.0 30 Q9UQN3,P40939,P10253,Q92804,P21912,P35637 6 +Lambdoidal craniosynostosis 0.671078300874706 0.5728778716339813 0.566727388371677 1.0 1.0 3 P16435 1 +Caudate atrophy 0.6708623010795325 0.5721764774812176 0.5672024216930924 1.0 1.0 3 P02792 1 +Spinal muscular atrophy 0.4585710728112311 0.5703179957523155 0.568462037459724 1.0 1.0 11 Q13510 1 +Seborrheic dermatitis 0.4614523412956408 0.5702926854754574 0.5684792011319397 1.0 1.0 9 P37287,O00192,P21964 3 +Head banging 0.6702769020519188 0.5702770497653503 0.5684898043085866 1.0 1.0 3 Q7Z5J4 1 +Aortic valve calcification 0.6689896531364423 0.5661079870253375 0.5713203741136426 1.0 1.0 3 O75844 1 +Peripheral pulmonary artery stenosis 0.4602202965510109 0.5650109125624735 0.572066341740948 1.0 1.0 9 Q6PGP7,Q15477 2 +Asthenia 0.5184035652002529 0.5638541949111224 0.572853365327195 1.0 1.0 4 O00754 1 +Impaired social interactions 0.36532329952756 0.5628109041483311 0.5735636543966918 1.0 1.0 51 Q15907,Q9UHX1,O75380,O43676,Q8N183,Q9P0J0,Q13509,Q9BU61,Q8TB37,Q709C8,Q9Y6M9,Q96CU9,O75306,Q15067 14 +Generalized joint laxity 0.4547151171943687 0.5620545076027721 0.5740788821933944 1.0 1.0 12 Q9UHX1,Q9Y487 2 +Aplasia hypoplasia of the ribs 0.3924854143588341 0.5618847868546039 0.5741945194430174 1.0 1.0 25 Q9Y619,Q9UHX1,Q96EX3 3 +Facial hypotonia 0.4566265574014374 0.561666075179444 0.5743435523508003 1.0 1.0 11 O00754,P10253 2 +Macular purpura 0.4453773864763574 0.5573898732249761 0.5772610829370115 1.0 1.0 15 Q15833,Q8NCH0,P04062 3 +Cardiovascular calcification 0.4584598003046694 0.5541341907569909 0.5794870123570899 1.0 1.0 8 O75844 1 +Abnormal qt interval 0.4583181123327903 0.5535409354804168 0.5798930579307335 1.0 1.0 8 P40939 1 +Myositis 0.4574607685841613 0.5532202871999422 0.5801125768490072 1.0 1.0 9 Q9NZ08,P28070,P01889 3 +Status epilepticus 0.3621657172518501 0.5519020376680885 0.5810154722405363 1.0 1.0 50 Q01105,Q13510,P42892,Q15392,P07602 5 +Heat intolerance 0.4861940808112412 0.5463950783838305 0.5847943924585577 1.0 1.0 5 Q05086,P61978 2 +Preaxial polydactyly 0.4459940897139118 0.5453935093717212 0.5854829035237219 1.0 1.0 14 Q9UHX1 1 +Poor suck 0.3744171490119631 0.5452482826669824 0.5855827683175425 1.0 1.0 27 P22695,P40939,Q05086,O75306,O75648 5 +Vertigo 0.3896745664045058 0.5442540208805462 0.5862666823651452 1.0 1.0 25 P06280,P49327,P10644,O15460,Q02978,P01889,O00170,Q6UN15,Q9NZ08,P0DP25,P21912 11 +Abnormality of the larynx 0.3592580690947713 0.5429851204615994 0.5871400472838189 1.0 1.0 49 P07737,P21964,Q9UHX1,Q13510,Q9UQN3,Q7Z5J4,Q14739,Q92804,P07602,O00192,Q96EX3,P35637 12 +Acute phase response 0.3737258860784258 0.5406319447493986 0.5887612949613557 1.0 1.0 27 P10644,O15460,P01889,Q15833,P41440,P02792 6 +Arthrogryposis multiplex congenita 0.3391366088245157 0.5400489492354006 0.5891632757225045 1.0 1.0 38 O75844,Q15392,Q969X5,P04062,Q15650,Q8NCH0 6 +Toxemia of pregnancy 0.454453749479247 0.5363919136355408 0.5916877188856564 1.0 1.0 6 O43772,P49366 2 +Abnormal cerebral artery morphology 0.4373971736751609 0.5356880762642778 0.5921741457291805 1.0 1.0 16 P05067,P10644,P42224,Q9UBS4,P10253 5 +Pes valgus 0.4488558701007721 0.5356332052482731 0.5922120751753313 1.0 1.0 12 Q15650,Q9UHX1 2 +Thin ribs 0.448668666078648 0.5347935336358369 0.5927926349859725 1.0 1.0 12 O75844,Q9Y619 2 +Lymphedema 0.4499892484798185 0.5323496622860384 0.5944838421040206 1.0 1.0 11 P06280,P52732 2 +Slender long bone 0.447867181159796 0.5312018479895106 0.5952789125184137 1.0 1.0 12 Q9Y619,Q32P28,Q9Y487 3 +Antiphospholipid antibody positivity 0.8030769230769241 0.5304170298092511 0.5958228212022447 1.0 1.0 2 P42224 1 +Fibroadenoma of the breast 0.8030769230769237 0.5304170298092502 0.5958228212022454 1.0 1.0 2 P10644 1 +Ankyloglossia 0.4523554951971791 0.5275526224008372 0.5978098837042709 1.0 1.0 7 Q6DKJ4,O75844 2 +Abnormal thrombosis 0.3713810103060521 0.5250177722542801 0.5995708363187164 1.0 1.0 27 O75874,O15460,P48735,P01889,Q9NZ08,P52732 6 +Gastrointestinal obstruction 0.4351111890808983 0.524524719554036 0.5999136312070596 1.0 1.0 16 P50336,P42892,Q93063,Q01844 4 +Large placenta 0.6559188438521741 0.5243910906664176 0.6000065519647524 1.0 1.0 3 O75844 1 +Purpura 0.4161478116023975 0.5172349127909115 0.6049921832040395 1.0 1.0 20 P21964,P10644,Q15833,Q6UN15,P04062,O00192,Q8NCH0 7 +Weakness of muscles of respiration 0.33394626633943 0.5131595175595673 0.6078397412044492 1.0 1.0 37 Q7RTS9,Q13510,P50570,P50336,P10253,Q969X5,Q8TD16,Q15650,Q15067 9 +Hypoplasia of the odontoid process 0.4481885879645096 0.5106764178462413 0.6095776562048207 1.0 1.0 7 P16278 1 +Cerebral hemorrhage 0.4430186368110869 0.5095888091586656 0.6103395656191464 1.0 1.0 12 P05067 1 +Flat forehead 0.4759836605411381 0.5076385319709036 0.6117068630412941 1.0 1.0 5 Q8NCH0 1 +Ovarian neoplasm 0.3970314354978035 0.5065625155045399 0.6124618150516963 1.0 1.0 23 O75874,P48735 2 +Thenar muscle atrophy 0.6501202645412028 0.506260487447797 0.6126737972405492 1.0 1.0 3 O60568 1 +Duplication involving bones of the feet 0.3969107582854367 0.505860758067075 0.6129544021700981 1.0 1.0 23 Q10713,Q14739,Q9H0F7,O00192,Q96EX3 5 +Abnormal atrioventricular valve physiology 0.3562515880138331 0.5056476494374349 0.6131040249046098 1.0 1.0 50 P06280,O00754,P10644,P01889,Q15904,P40939,O75844,Q9NZ08,P04062,Q9H0F7,Q15056,O75306 12 +Capillary malformation 0.4396905413474593 0.504276065850017 0.614067393990013 1.0 1.0 13 Q9UHX1,Q9Y5S9,Q6DKJ4,P41227,Q15056 5 +Stuttering 0.7935384615384453 0.5036194893998688 0.614528794333753 1.0 1.0 2 P00403 1 +Bone fracture 0.4463903934123037 0.5034365246951517 0.6146573975322562 1.0 1.0 7 Q13126 1 +Skin rash 0.4182803842301002 0.502474567276857 0.6153337380433737 1.0 1.0 19 Q06136,Q15833,P28070,Q14739 4 +Generalized hypopigmentation 0.4444641536526761 0.5024154176262626 0.6153753361164254 1.0 1.0 10 Q6PGP7,Q15477 2 +Abnormal periventricular white matter morphology 0.3373656408235568 0.4973261545351083 0.618959070858625 1.0 1.0 40 Q9UHX1,P17900,O43681,O75503,P07602,O75648 6 +Hamartomatous polyposis 0.6469535970248133 0.4964616529597815 0.619568736071697 1.0 1.0 3 Q15437 1 +Shuffling gait 0.4414989540661316 0.4953706763979354 0.6203384898468509 1.0 1.0 11 O75844 1 +Positive romberg sign 0.4427155369198536 0.4950002376765395 0.6205999527368338 1.0 1.0 10 Q8IV08,Q9H6K4 2 +Abnormal circulating sulfur amino acid concentration 0.4440670798119924 0.4946576170969776 0.6208418237215119 1.0 1.0 8 Q6PGP7 1 +Moderately reduced visual acuity 0.6460606830563735 0.4937120148082374 0.6215095787417471 1.0 1.0 3 O60313 1 +Chorioretinal dysplasia 0.443418577752096 0.4925765773336247 0.6223118014449955 1.0 1.0 6 P52732 1 +Abnormality of the radioulnar joints 0.7886153846153843 0.4900132328519918 0.6241245349716762 1.0 1.0 2 P16435 1 +Radioulnar dislocation 0.7886153846153843 0.4900132328519918 0.6241245349716762 1.0 1.0 2 P16435 1 +Recurrent fever 0.4379386190685432 0.4871645930171984 0.6261416947193033 1.0 1.0 12 Q15833,Q13510 2 +Torsade de pointes 0.7864615384615208 0.4841100291629573 0.6283077840049638 1.0 1.0 2 P0DP25 1 +Uveitis 0.4394696589242741 0.4813073893797262 0.6302980460283212 1.0 1.0 10 P49327,Q9UDY8,P14174,P01889 4 +Hypomimic face 0.4314297441304744 0.4779247440200299 0.6327037691886539 1.0 1.0 14 P35270,P04062,P02792 3 +Schwannoma 0.6406983618479467 0.4773254649353021 0.6331303804369244 1.0 1.0 3 P10644 1 +Kinetic tremor 0.3219605642969522 0.4757787544137513 0.634232007290825 1.0 1.0 33 P04080,O43681,Q14108,P41440,P07602 5 +Malignant neoplasm of the central nervous system 0.3852975772431246 0.4754110069078267 0.6344940506479322 1.0 1.0 24 P48735 1 +Abnormality of the gallbladder 0.3305640050896113 0.4721964375615778 0.6367865822892773 1.0 1.0 38 P04066,O43681,Q15437,P04062,Q15056,P07602 6 +Hamartoma 0.4165633288293952 0.4711972993463296 0.6374998471105862 1.0 1.0 18 O75874,P48735 2 +Depressed nasal ridge 0.4117669031434427 0.4688334265415851 0.6391887050723868 1.0 1.0 19 O00754,Q6PGP7,P16278 3 +Arm dystonia 0.4654729082361794 0.4686490908746848 0.6393204816420961 1.0 1.0 5 P02792 1 +Abnormality of salivation 0.3370912379757432 0.467119197903602 0.640414599647642 1.0 1.0 42 P15586,P31150,P07737,Q9UQN3,P01889,Q05086,Q14739,Q92804,Q9UET6,P35637 10 +Abnormal activity of mitochondrial respiratory chain 0.3632239444199985 0.4651852048666059 0.6417988329093047 1.0 1.0 57 Q70HW3,O75380,O43676,Q9UBX3,Q9UMS0,Q9Y6M9,O75306,Q9Y584,O75648 9 +Abnormal social behavior 0.3802403901472422 0.4643642613858513 0.6423867906726017 1.0 1.0 67 Q15907,Q9UHX1,O75380,O43676,Q8N183,Q9P0J0,O43681,Q13509,P05067,Q9BU61,Q8TB37,Q709C8,Q9Y6M9,Q15056,P07602,Q96CU9,O75306,Q15067 18 +Aphthous ulcer 0.4347987333050384 0.459054648904083 0.6461949226195167 1.0 1.0 6 Q9NZ08 1 +Abnormal circulating long chain fatty acid concentration 0.4349878276194426 0.4580309966186554 0.6469301722211653 1.0 1.0 8 P50542,P23786,Q9Y5Y5 3 +Central scotoma 0.4345812672978116 0.4578049081650694 0.6470926092692579 1.0 1.0 9 Q9H6K4,Q8WWV3,O75306,Q9H061 4 +Postaxial polydactyly 0.3755006335129511 0.4568225768663506 0.6477985768443957 1.0 1.0 25 Q9Y366,Q10713,P98175,O00459,Q14739,P30153,Q9H0F7,Q96EX3,P61978 9 +Decreased muscle mass 0.4086213968224014 0.4527592443379106 0.6507221138082611 1.0 1.0 19 Q8TAA9,Q9Y487,P04066 3 +Neoplasm of the endocrine system 0.3298077100703282 0.4522562909415933 0.651084360161232 1.0 1.0 39 O75874,P42892,Q15437,P48735,Q9UBS4 5 +Deep plantar creases 0.460490287018221 0.4505140795123281 0.6523398044144351 1.0 1.0 5 Q9Y487,P61978 2 +Psychotic mentation 0.4604098757616653 0.4502233314956513 0.6525494146173036 1.0 1.0 5 P48637,P00403 2 +Abnormalities of placenta or umbilical cord 0.4160727327266745 0.4496825514655118 0.652939354433743 1.0 1.0 17 O75844,Q6PGP7 2 +Limited wrist movement 0.4601687656537886 0.4493519060149263 0.6531778194051845 1.0 1.0 5 O75844 1 +Abnormal circulating progesterone level 0.4318591971973811 0.4477754188791578 0.6543152853411356 1.0 1.0 6 P49770,Q9UI10 2 +Decreased circulating progesterone 0.4318591971973811 0.4477754188791578 0.6543152853411356 1.0 1.0 6 P49770,Q9UI10 2 +Postural instability 0.4156510126818502 0.4476460831782622 0.6544086392315964 1.0 1.0 17 O75503,P41440,P04062 3 +Erythema 0.4029702154497712 0.4474656670902006 0.6545388717295884 1.0 1.0 20 Q06136,P51648,P00403 3 +Pelvic kidney 0.4322298293826264 0.4470550952798257 0.6548352802279549 1.0 1.0 8 Q9UHX1 1 +Elevated circulating alanine aminotransferase concentration 0.4311301456292545 0.4465754898493989 0.6551815958053486 1.0 1.0 10 Q15904 1 +Corpus callosum atrophy 0.4214160456360921 0.444466258254907 0.6567055185783639 1.0 1.0 15 O75503,O60313,Q9H9P8,O00754 4 +Thyroid adenoma 0.4843275189533935 0.4428544052964162 0.6578710483677914 1.0 1.0 4 P10644 1 +Bifid uvula 0.3207783434445369 0.4380303653591694 0.6613642715456605 1.0 1.0 35 Q9Y619,Q6PGP7 2 +Hypopigmented skin patches 0.3575821128817092 0.4347083828603366 0.6637741128648664 1.0 1.0 27 P21964,Q15437,P53634,Q8IZA0,O00192,P07602,P21912 7 +Polyhydramnios 0.3487104101868547 0.4342049873775592 0.6641395917261319 1.0 1.0 51 O75844,Q6PGP7,Q70HW3,P04062 4 +Hypoplastic heart 0.625698482632316 0.4326880253591246 0.6652414303881506 1.0 1.0 3 Q12768 1 +Fulminant hepatic failure 0.625398423279216 0.4318138826583041 0.6658766887679299 1.0 1.0 3 P40939 1 +Myelopathy 0.4807197004295711 0.4306687816764967 0.6667092211890737 1.0 1.0 4 P16278 1 +Myoglobinuria 0.4260557350622997 0.4298036293546637 0.6673384925698991 1.0 1.0 11 P23786,P40939 2 +Amaurosis fugax 0.4274563746004514 0.4290567977617898 0.6678818912072457 1.0 1.0 9 O15460 1 +Urinary retention 0.4269070285456565 0.4289586638194647 0.6679533069359038 1.0 1.0 6 Q8TAA9 1 +Hyperinsulinemic hypoglycemia 0.4269050821389267 0.428951314904944 0.6679586551360015 1.0 1.0 6 P40939 1 +Abnormal cry 0.425676695384362 0.4282244444685792 0.6684877210836864 1.0 1.0 11 Q15650,Q13510 2 +Abnormality of skull ossification 0.4177962466805357 0.427915855336266 0.6687123831488822 1.0 1.0 15 P54802,O75718,O75844,Q14739,Q32P28 5 +Neurogenic bladder 0.4262587514219245 0.4266045594198162 0.6696673762560155 1.0 1.0 10 P50336,Q8TAA9 2 +Short ribs 0.4251200753755396 0.4259081805465292 0.6701747537317995 1.0 1.0 11 Q9Y619 1 +Increased blood pressure 0.3865639921361685 0.4240316910432333 0.6715427013802349 1.0 1.0 74 P06280,Q8TAA9,Q93063,P42892,Q9H0F7,P21912,P31153,Q9UBS4,P35610,Q15056,P21964,P00403,P50336,O75844,Q9UMS0,P04062,O00192,Q10713,P10644,P01889,P42224,P37287 22 +Abnormal facial expression 0.3169080841112158 0.4219905376907087 0.6730319241016489 1.0 1.0 34 P35270,Q05086,Q969X5,P04062,P02792,Q15043 6 +Ulnar deviation of the wrist 0.4522143599932517 0.4209227327927254 0.6738115047023228 1.0 1.0 5 P16278 1 +Fatty replacement of skeletal muscle 0.4251610637308921 0.419264593557093 0.6750227696699804 1.0 1.0 8 Q9H9S5,P22626,Q96AD5,P51114,P55072,Q8NFF5 6 +Elevated circulating parathyroid hormone level 0.4749666526139809 0.4115140198704106 0.6806956631579621 1.0 1.0 4 P10644 1 +Elevated circulating growth hormone concentration 0.758769230769224 0.4110576764664035 0.6810302432271689 1.0 1.0 2 P10644 1 +Pituitary prolactin cell adenoma 0.758769230769224 0.4110576764664035 0.6810302432271689 1.0 1.0 2 P10644 1 +Arterial rupture 0.617898888479486 0.4102158935837766 0.6816475829397746 1.0 1.0 3 Q9NWM8 1 +Glomus jugular tumor 0.7578461538461567 0.4087180284725859 0.6827466017692609 1.0 1.0 2 P21912 1 +Abnormal spinal meningeal morphology 0.7578461538461565 0.4087180284725856 0.6827466017692612 1.0 1.0 2 P31153 1 +Proportionate tall stature 0.7578461538461501 0.4087180284725699 0.6827466017692727 1.0 1.0 2 O00170 1 +Fasting hyperinsulinemia 0.4739021112052753 0.4080078366273612 0.6832679215445303 1.0 1.0 4 P00367,P40939 2 +Vitreous floaters 0.6165834014693132 0.4064777763525448 0.6843915828138099 1.0 1.0 3 P04439 1 +Vertebral fusion 0.4188961897531666 0.4053601120386417 0.6852128264837902 1.0 1.0 12 Q9UHX1 1 +Abnormal atrioventricular conduction 0.4167412533741772 0.4031490399942377 0.6868385859683439 1.0 1.0 13 P06280,O43772 2 +Skin erosion 0.4205305140232978 0.4025256823660718 0.6872971913292603 1.0 1.0 7 O75844 1 +Ankyloblepharon 0.4467175406553899 0.4016538418294526 0.6879387990363321 1.0 1.0 5 O75569,P41227 2 +Dysgraphia 0.4163865938610043 0.4016310019891136 0.6879556104278666 1.0 1.0 13 P05067,Q9UQN3 2 +Pneumothorax 0.4192540647741521 0.4003598974137417 0.6888914569222961 1.0 1.0 6 Q8NCH0,Q93063 2 +Palmar telangiectasia 0.7544615384615394 0.4001945203786811 0.6890132502596815 1.0 1.0 2 Q14739 1 +Cupped ear 0.4175834080779914 0.3998644616347587 0.6892563489508072 1.0 1.0 12 Q15392 1 +Neonatal hypoglycemia 0.4184035008577539 0.3982253312080361 0.6904640951919434 1.0 1.0 11 P40939 1 +Abnormal circulating carbohydrate concentration 0.3243800092491785 0.3967733569919798 0.691534599515458 1.0 1.0 40 Q70HW3,O75380,O43676,Q8N183,P22695,Q9BU61,Q8TB37,Q9Y6M9,Q96CU9,O75306 10 +Hyporeflexia of upper limbs 0.7529230769230795 0.3963491088350813 0.6918475036283567 1.0 1.0 2 Q15067 1 +Wide cranial sutures 0.4191266795593329 0.3959495015436539 0.6921422820022838 1.0 1.0 8 O75844,O75718 2 +Abnormal epidermal morphology 0.3972799331557961 0.3958234990415429 0.69223523996257 1.0 1.0 19 Q06136,O75844,P01889 3 +Dilatation of the cerebral artery 0.4165440441733516 0.395527599733971 0.6924535569971528 1.0 1.0 12 P42224,P10644,P10253,Q9UBS4 4 +Wide nose 0.3205410888848594 0.3946946702551569 0.6930682366225496 1.0 1.0 38 Q6PGP7,P04066,Q15477,P52732,Q96EX3 5 +Disproportionate short limb short stature 0.3772904793951476 0.3943049114322026 0.693355937622055 1.0 1.0 23 Q9Y366,O75718,P10644,Q6DKJ4,Q15392,Q14739,Q32P28,Q96EX3 8 +Deviation of the 2nd finger 0.4692708708405717 0.3928969617079907 0.6943955857098625 1.0 1.0 4 Q9H6K4 1 +Smooth muscle antibody positivity 0.7486153846153855 0.3856793026983868 0.6997341931725565 1.0 1.0 2 P49327 1 +Metaphyseal sclerosis 0.4413304588851255 0.3830839347719708 0.7016575309127968 1.0 1.0 5 Q9Y3A5,Q9H1A4,Q14807,P61011 4 +Abnormal cardiac ventricular function 0.4039963591055513 0.3779713475395331 0.7054518791625926 1.0 1.0 16 O75844,P10253 2 +Triangular mouth 0.4137102153858826 0.3770320712898484 0.7061497712422149 1.0 1.0 7 Q6DKJ4,Q10713 2 +Oromandibular dystonia 0.4638265128343408 0.3754372036155728 0.7073353405350549 1.0 1.0 4 Q15043,P35637 2 +Extramedullary hematopoiesis 0.4635193738781347 0.3744622478228637 0.7080604387351344 1.0 1.0 4 P98175 1 +Bulbar signs 0.4114100108765752 0.3699508954598228 0.711419078359099 1.0 1.0 11 O43681,Q92734,P04062,P35637,P07602 5 +Hydrocele testis 0.4117738498673716 0.3698889404124947 0.7114652422242909 1.0 1.0 7 Q9UBX3 1 +Oral pharyngeal dysphagia 0.4035462205315211 0.3549504489413106 0.7226267131874529 1.0 1.0 14 Q01105,Q7Z5J4,Q13510 3 +Abnormal circulating lipid concentration 0.3879571457402326 0.3508179041274107 0.7257249643099875 1.0 1.0 81 P06280,P28070,Q7Z5J4,Q15904,P07602,O43772,Q8N511,Q9NVI7,Q92734,P37268,Q14739,P61916,O75844,O95470,P23786,P40939,Q15833,Q15392,O75648 19 +Progressive external ophthalmoplegia 0.4055654280301242 0.3446987737376585 0.7303208401185239 1.0 1.0 10 P00403 1 +Nephrolithiasis 0.3826259829041321 0.3441714055139567 0.7307173852633477 1.0 1.0 20 Q4J6C6,Q8NCH0,Q9UBS4 3 +Thin skin 0.3680659463108747 0.3438715394282379 0.7309428963339579 1.0 1.0 23 O75844,Q9Y619,Q13126 3 +Decreased plasma carnitine 0.4034852529850493 0.3421639914846072 0.732227482140414 1.0 1.0 12 O43772,P23786,P40939 3 +Protuberant abdomen 0.4039888518317457 0.3416146535497858 0.7326409080336407 1.0 1.0 7 Q9Y366,P04062 2 +Abnormal pulmonary valve morphology 0.4018790307650278 0.3408706658963963 0.7332009489188458 1.0 1.0 13 Q6DKJ4,P10644,O00192 3 +Wrist flexion contracture 0.4037612111323628 0.3407988940978291 0.73325498306024 1.0 1.0 7 Q969X5 1 +Thoracic scoliosis 0.4001070796056126 0.3404512356846079 0.7335167399972962 1.0 1.0 14 O75844,Q9UHX1 2 +Color vision defect 0.3923706588695043 0.3387130592832754 0.7348259017342966 1.0 1.0 17 O60313,Q9H6K4,Q8WWV3,Q9H061 4 +Thoracic hypoplasia 0.3041258099450057 0.3382320978481431 0.7351882891635411 1.0 1.0 33 O75718,Q9UHX1,Q9Y366,P16435,Q8WVQ1,Q14739,P04062,P41227,O94766,Q9Y281,Q96EX3 11 +Ectopia lentis 0.4275810336322709 0.3371898124269289 0.7359738165830474 1.0 1.0 5 Q03518 1 +Apraxia 0.3606711525601645 0.3330461490733851 0.739099447781671 1.0 1.0 66 P35270,Q10713,Q6DKK2,Q9UQN3,Q13509,Q7Z5J4,P05067,O14773,P04062,P35637,Q9Y619,Q9NQT5,O75648 13 +Scotoma 0.4011183847296439 0.3327274594728607 0.7393400197817404 1.0 1.0 12 O60313,Q9H6K4,Q8WWV3,Q9H061,O75306 5 +Genu valgum 0.3069288892661546 0.3324769725280575 0.7395291249546292 1.0 1.0 35 Q7RTS9,Q93063,O00754,P16278,Q13509,Q04721,Q9Y281,Q15056,Q9Y619,Q8N0X7 10 +Brain neoplasm 0.4260014463602987 0.3320625737029736 0.7398420100124374 1.0 1.0 5 P06400 1 +Retinal coloboma 0.402235054287929 0.3320026395037979 0.739887265914833 1.0 1.0 10 Q9UHX1 1 +Diplopia 0.3708046974289032 0.3309172510543154 0.7407069909621316 1.0 1.0 22 O14773,O15460,P04062 3 +Myalgia 0.3260963831614828 0.3306738939830769 0.7408908235662885 1.0 1.0 46 P06280,Q93063,O60313,O15460,P23786,P01889,P46020,P50570,P40939,Q9NZ08,Q14739,O00192 12 +Restless legs 0.3997833584079229 0.3304968817024817 0.7410245484267477 1.0 1.0 6 P02792 1 +Temporal optic disc pallor 0.7252307692307594 0.330356498057222 0.7411306075543309 1.0 1.0 2 O60313 1 +Morning glory anomaly 0.7252307692307594 0.330356498057222 0.7411306075543309 1.0 1.0 2 O60313 1 +Neoplasm of the breast 0.3100054390898805 0.3302513203369838 0.7412100720084596 1.0 1.0 31 O75874,P49327,P10644,Q15437,P48735,P21912 6 +Thickened calvaria 0.4018148825806901 0.3301847331246888 0.7412603817751036 1.0 1.0 9 O00754,P16278 2 +Splenomegaly 0.3994081256215591 0.3294150776251341 0.7418419728894303 1.0 1.0 90 O15118,P04066,Q15437,Q15904,P10253,P07602,P15586,P16278,Q13510,P61916,Q15477,Q14108,Q9NZ08,P04062,P54802,Q6PGP7,Q10713,P01889,Q15833,Q15392 20 +Cutaneous syndactyly 0.4015164194726132 0.3290807109556022 0.7420946834385238 1.0 1.0 9 Q9Y619 1 +Cardiac arrest 0.3257680404595992 0.3268729550579327 0.7437639771894247 1.0 1.0 29 O43772,O15460,P0DP25,P04062 4 +Knee flexion contracture 0.3399158559173637 0.3238950969314167 0.7460174561514248 1.0 1.0 27 O00459,Q96AY3,P23786,Q969X5,Q06210,P37268,Q86XL3,O95817,Q8TD16,P21912 10 +Gonadal neoplasm 0.332789301620529 0.3237315230976991 0.746141302984785 1.0 1.0 28 O75874,P48735,Q01844 3 +Mixed hearing impairment 0.3991031329376467 0.3215767825901366 0.7477733350841027 1.0 1.0 8 O00754,Q9NWM8,P62857 3 +Abnormal lung lobation 0.3948605195580595 0.3186518072273898 0.7499905631664405 1.0 1.0 14 Q9UHX1,P21964,Q14739,O00192 4 +Dicarboxylic aciduria 0.3632828077590384 0.3183114751862271 0.7502486807155428 1.0 1.0 23 P40939,P23786,P48735 3 +Hypercholesterolemia 0.3960800709816527 0.3173650139428788 0.7509666509136874 1.0 1.0 13 Q8N511 1 +Thick lower lip vermilion 0.3224085724312071 0.3165169081573129 0.7516101935032813 1.0 1.0 45 P06280,P15586,Q9Y619,P04066 4 +Abnormality of the pharynx 0.3293521268176388 0.3163926228892571 0.7517045156777094 1.0 1.0 49 P15586,P54802,Q7RTS9,P16278,Q13510,Q03518,Q86YV9,Q7Z5J4,P01889,O15460,Q15833,O00192,P13051 13 +Tibial torsion 0.7178461538461567 0.313836416061531 0.753645284653278 1.0 1.0 2 Q9Y5S9 1 +Retrocollis 0.7175384615384478 0.3131583111911029 0.7541603894061966 1.0 1.0 2 P35637 1 +Visual field defect 0.3198656152113209 0.3107415414822234 0.7559971139881949 1.0 1.0 44 Q8WWY3,P04439,P00403,O60313,O15460,P01889,Q9H6K4,Q8WWV3,Q9H061,Q9H0F7,O75306 11 +Premature birth 0.3162809599886882 0.3101596204823456 0.756439575531314 1.0 1.0 42 O43676,O75844 2 +Abnormal glycosylation 0.3617067033375494 0.309983555216634 0.7565734618679045 1.0 1.0 23 Q8N511,Q15904 2 +Abnormal sacrum morphology 0.3067220407712435 0.3069157143173687 0.7589075276738331 1.0 1.0 31 P49366,Q8TAA9,P04066,P01889,Q6DKJ4,Q14739 6 +Diastema 0.4405250504608364 0.3046977581346855 0.7605963572237759 1.0 1.0 4 Q9BSJ2 1 +Bilateral ptosis 0.3924748389097758 0.3029939605590256 0.7618944641754481 1.0 1.0 13 O60313,Q13509,O75306 3 +Progressive cerebellar ataxia 0.3045940379607599 0.3021380225852401 0.7625468482389683 1.0 1.0 36 Q8N183,Q9Y487,O14773,P41440,Q9Y619,O75306 6 +Decreased calvarial ossification 0.43938558914063 0.3014142046721106 0.7630986639179831 1.0 1.0 4 O75844 1 +Abnormality of adrenal morphology 0.3292049215622966 0.3012271356123984 0.7632412989900417 1.0 1.0 28 O75874,P48735 2 +Encephalocele 0.3926757052265421 0.2997005351154764 0.764405590395987 1.0 1.0 12 Q6ZXV5,Q10713 2 +Secundum atrial septal defect 0.4385682376993578 0.2990694185792291 0.7648870794416669 1.0 1.0 4 Q15650 1 +Aphasia 0.3057253450324248 0.2974699437403238 0.7661077514072492 1.0 1.0 37 P00403,P05067,Q9UQN3,Q7Z5J4,Q9H9P8,O75648 6 +Frequent falls 0.3074442345338248 0.2971161451591364 0.7663778385983764 1.0 1.0 38 P07602,P04062,Q13510 3 +Abnormal vitreous humor morphology 0.3900869053905427 0.2930130151647696 0.7695122034344299 1.0 1.0 7 P06400 1 +Lethal skeletal dysplasia 0.435868001821299 0.2913862411479867 0.7707559362068814 1.0 1.0 4 Q96EX3 1 +Optic disc pallor 0.329167468337576 0.2902885398569753 0.7715955054414707 1.0 1.0 51 Q8WWY3,P04439,Q8IYI6,Q10713,O75380,O43676,O60313,Q8N183,O75306,Q9H6K4,Q8WWV3,Q9BU61,Q8TB37,Q9H061,O00754,Q9Y6M9 16 +Congestive heart failure 0.3444996546688074 0.2900581397081685 0.771771759406217 1.0 1.0 60 P06280,Q70HW3,P16278,P00403,P10644,P40939,P42224,P10253,Q9BU61,Q15056,Q15650,P21912,O75306 13 +Microretrognathia 0.3858157356242643 0.2890002060037498 0.7725812199114894 1.0 1.0 15 Q9UHX1,Q8WVQ1,P41227,Q15650,Q8NCH0 5 +Postural tremor 0.3808674664906808 0.2877783410264209 0.7735164176988722 1.0 1.0 17 Q14108,O75306,O14773 3 +Abnormal eyelid physiology 0.38994676288199 0.2872081207849434 0.7739529686656215 1.0 1.0 9 P04350,P02792 2 +Neck muscle weakness 0.3829431296226632 0.2858991075444518 0.7749553973067735 1.0 1.0 16 P07602,Q15650 2 +Limited knee extension 0.7039999999999912 0.2841483995510589 0.7762966573913881 1.0 1.0 2 Q7RTS9 1 +Dysgenesis of the hippocampus 0.7039999999999782 0.2841483995510317 0.776296657391409 1.0 1.0 2 Q13509 1 +Abnormal patella morphology 0.3333078874150774 0.2841412930427926 0.77630210322326 1.0 1.0 27 Q6ZXV5,P21964,Q9Y5S9,Q96AY3,Q8WVQ1,Q15056,Q9Y619,O00192 8 +Abnormal metatarsal morphology 0.319043487497132 0.2831941356160479 0.7770280235337248 1.0 1.0 29 Q7RTS9,Q9Y366,P16435,P10644,Q13509,Q8WVQ1,Q15392,O94766,O43505 9 +Calf muscle pseudohypertrophy 0.7030769230769227 0.2822300837911898 0.7777670920242279 1.0 1.0 2 Q13049 1 +Metatarsus valgus 0.7030769230769134 0.2822300837911707 0.7777670920242425 1.0 1.0 2 O43505 1 +Emotional lability 0.3278902604484071 0.2812314537782726 0.7785328811573171 1.0 1.0 51 Q9UI10,Q9P0J0,Q8N183,P49770,Q9UQN3,Q13509,O43681,P10644,P02792,P07602,Q96CU9,O75306,Q92804,P35637 14 +Increased urine alpha ketoglutarate concentration 0.4094893315077095 0.2803891612255121 0.7791789517726413 1.0 1.0 5 P00367 1 +High myopia 0.3865488933378763 0.2775668758617708 0.7813448625238468 1.0 1.0 8 Q9Y487 1 +Tapered finger 0.2993017245483808 0.2765798452748688 0.7821027423368541 1.0 1.0 35 Q06136,P42892,P23786 3 +Prominent antihelix 0.7003076923076808 0.2765214568807802 0.7821475816667898 1.0 1.0 2 P98175 1 +Abnormality of the nasolabial region 0.3851815019819095 0.2764827018287398 0.7821773439839914 1.0 1.0 7 Q9Y487 1 +Prominent nasolabial fold 0.3851815019819095 0.2764827018287398 0.7821773439839914 1.0 1.0 7 Q9Y487 1 +Red eye 0.3749711161809516 0.2745677059158956 0.7836483800002436 1.0 1.0 18 Q10567,Q9NZ08,P28070,P01889 4 +Misalignment of incisors 0.5656771459007287 0.2745543582590518 0.7836586359460831 1.0 1.0 3 Q9BSJ2 1 +Focal segmental glomerulosclerosis 0.3716685752369393 0.2742114634786258 0.783922119061927 1.0 1.0 19 Q14108,O95470 2 +Coxa valga 0.3596084289820353 0.274094539960556 0.7840119697024484 1.0 1.0 22 O75844,Q9Y619,P04066 3 +Retinal atrophy 0.3314396128559579 0.2730913172724051 0.7847830209564572 1.0 1.0 27 Q8WWY3,Q10713,P51648,P04062,O75648 5 +Low levels of vitamin d 0.3851372186247408 0.2703553825261747 0.786886861949704 1.0 1.0 9 P46783,P62913,Q9NSD9,Q10471,P61011,Q9Y3A5,Q01968,Q13043 8 +Thromboembolism 0.4057950100494188 0.2693307239301022 0.7876751911182327 1.0 1.0 5 P10644 1 +Increased vertebral height 0.4278047062506855 0.2690310226123379 0.7879058098520242 1.0 1.0 4 O00754,Q04721 2 +Ascending tubular aorta aneurysm 0.5626433519651093 0.2675385707491101 0.7890545209259052 1.0 1.0 3 O75844 1 +Abnormal oral physiology 0.332380082468876 0.2646588447533302 0.7912722843344697 1.0 1.0 55 P15586,P55795,P31150,P07737,Q13228,Q9UQN3,Q13509,O15460,P10644,P01889,P35637,Q05086,Q6UN15,Q14739,Q92804,Q9UET6,Q8N0X7 17 +Vertebral segmentation defect 0.3082168308530477 0.2621581012009598 0.7931995543496226 1.0 1.0 30 Q9Y619,Q9UHX1 2 +Turricephaly 0.3825287000711402 0.26139761908468 0.793785892925088 1.0 1.0 12 O00192,P07237,P16435,P21964 4 +Abnormal circulating fatty acid anion concentration 0.3812139389024682 0.2593786971461481 0.7953430646325619 1.0 1.0 13 O43772,P23786,P40939 3 +Widely patent fontanelles and sutures 0.402408075330226 0.2593613074452519 0.7953564806641196 1.0 1.0 5 O75844 1 +Narrow iliac wing 0.4240757732357227 0.2589971436560429 0.7956374443540084 1.0 1.0 4 P50542,Q9NR45 2 +Elevated circulating aspartate aminotransferase concentration 0.3817404153986826 0.2584890296868958 0.7960295143621328 1.0 1.0 12 P40939 1 +Upper limb asymmetry 0.6907692307692319 0.2573953910355674 0.7968735604814825 1.0 1.0 2 Q15555 1 +Intracranial hemorrhage 0.3513406121768664 0.2564592976171397 0.797596205458893 1.0 1.0 23 O75844,P05067,P04062 3 +Abnormality of visual evoked potentials 0.3559475309544418 0.2560535467682198 0.797909490754392 1.0 1.0 22 P07602 1 +Joint contracture of the hand 0.3221283338658575 0.2528731424425182 0.8003662443245698 1.0 1.0 50 O75844,Q9Y619,Q8IZA0,Q15392 4 +Abnormality of the vertebral endplates 0.3760517041273229 0.2518128480745004 0.8011857259400423 1.0 1.0 6 Q7RTS9 1 +Adducted thumb 0.3398788038797422 0.2516617422828441 0.8013025306053234 1.0 1.0 25 P42892,Q86XL3 2 +Speech articulation difficulties 0.399445642131196 0.2507762440718088 0.8019871092709983 1.0 1.0 5 P30038,P21359,Q8N3U4,P08754 4 +Inguinal freckling 0.5544849168258601 0.2491786179591474 0.8032226182792002 1.0 1.0 3 P21359 1 +Abnormal electroretinogram 0.2954487865685066 0.249042710446866 0.8033277438116038 1.0 1.0 35 P50897,O14773,P40939 3 +Profound global developmental delay 0.3767908138606313 0.2467857952735021 0.8050740042743239 1.0 1.0 14 P56589,O60313,P37268,Q9Y5Y5,P50542 5 +Ectopic calcification 0.3313919565568833 0.2460369924460017 0.8056535966402603 1.0 1.0 56 P00403,O60313,P05067,P06400,P10644,P23786,P42224,O75844,Q14739,P04062,Q9Y5Y5,O00584 12 +Hypopigmented macule 0.3963658761934063 0.2419866969492229 0.8087904712435656 1.0 1.0 5 Q9H488,Q15149,P21359,Q8NBL1 4 +Abnormal talus morphology 0.3526450898273061 0.2400223963536628 0.8103128942534763 1.0 1.0 22 O75844,Q9UHX1,Q969X5,Q9UPT5 4 +Microcornea 0.3048100045783795 0.2399198628672868 0.8103923821700239 1.0 1.0 30 Q7Z5J4,O15347,Q9NWM8,P52732,Q15555,Q8NCH0,O43505 7 +Expressive language delay 0.3767777394109599 0.2395594842461601 0.8106717770972891 1.0 1.0 11 Q9UHX1,Q13509,Q7Z5J4 3 +Muscle stiffness 0.3603772618281488 0.238955922182767 0.8111397616943512 1.0 1.0 20 P07602,Q15392,P23786,P46020 4 +Abnormality of skin adnexa physiology 0.3078308498773975 0.2375991194257505 0.81219203355605 1.0 1.0 43 P06280,O15269,P04080,P35270,P04066,O15460,P01889,Q15650,Q9UDY8 9 +Abnormal systemic blood pressure 0.3855582192957535 0.2349748028876822 0.8142282901273825 1.0 1.0 90 P06280,Q8TAA9,Q93063,P42892,Q9H0F7,P07602,O43772,P21912,P31153,Q9UBS4,P35610,Q15056,P49366,P21964,P00403,P50336,O75844,Q9UMS0,P04062,O00192,Q10713,O43681,P10644,P01889,P42224,P37287 26 +Recurrent fractures 0.2898304329387356 0.2343299293611126 0.8147288523836913 1.0 1.0 33 O75874,O75718,P48735,Q32P28,Q13126 5 +Gowers sign 0.3719989112554518 0.2337818160445891 0.8151543671314727 1.0 1.0 15 Q13510,Q9Y281,Q8TD16,Q5T8D3,Q13049 5 +Heart block 0.3512765084973338 0.2334485015270128 0.8154131546060097 1.0 1.0 22 P06280,O43772,P23786 3 +Abnormal visual electrophysiology 0.324450192964051 0.2334475739349938 0.8154138748223616 1.0 1.0 53 P40939,P50897,O75503,O14773,P07602 5 +Difficulty standing 0.36803316689173 0.2270407477854999 0.8203920572434666 1.0 1.0 6 Q92734 1 +Penetrating foot ulcers 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Trophic changes related to pain 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Impaired distal tactile sensation 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Emg slow motor conduction 0.6735384615384465 0.224994346217289 0.8219836725779712 1.0 1.0 2 O15269 1 +Abnormal size of the clitoris 0.3631768097831168 0.2239153646185545 0.8228231600231966 1.0 1.0 18 Q9Y619,P16435,P51809,Q9Y5Y5,P50542 5 +High narrow palate 0.2865249395515566 0.2235584680469828 0.82310088339776 1.0 1.0 32 Q9Y619,P23786 2 +Drowsiness 0.3668046377802143 0.2233320643883853 0.8232770736267556 1.0 1.0 6 O00754 1 +Systemic lupus erythematosus 0.3895903911302733 0.2231461787870318 0.8234217388447171 1.0 1.0 5 P29144,P49327,P12955,Q9UJV9 4 +Eeg with multifocal slow activity 0.3695333656278586 0.2215719948182335 0.8246470855031351 1.0 1.0 8 P38606,Q05639,O95319 3 +Emg axonal abnormality 0.669846153846138 0.2184168878369344 0.8271043085742573 1.0 1.0 2 Q92734 1 +Raynaud phenomenon 0.36510327804377 0.2182348293177223 0.8272461491506311 1.0 1.0 6 O75844 1 +Abnormal endocrine physiology 0.3862511483617712 0.2141169592578898 0.830455850897627 1.0 1.0 5 P50336,P16435 2 +Fatiguable weakness of proximal limb muscles 0.4062110671712505 0.2137062000151384 0.8307761761257297 1.0 1.0 4 Q92734 1 +Urinary incontinence 0.2988807460443404 0.2118839513786387 0.8321975712855303 1.0 1.0 40 Q8TAA9,O43681,Q9UQN3,P07602,Q9UET6 5 +Abnormally ossified vertebrae 0.3851842541116838 0.2112683321343052 0.8326778924933071 1.0 1.0 5 Q96EX3 1 +Absent or minimally ossified vertebral bodies 0.3851842541116838 0.2112683321343052 0.8326778924933071 1.0 1.0 5 Q96EX3 1 +Hyperkeratosis 0.3313002216952802 0.211000361461933 0.8328869892993163 1.0 1.0 59 P06280,O15269,Q10567,P04066,Q15437,P53634,P51648,O75844,Q9NWM8,P04062,Q06136,Q15650,P61966 13 +Entropion 0.367279330816374 0.2108736761974866 0.8329858455925048 1.0 1.0 9 O75844 1 +Hypoglycemic coma 0.3671725500640977 0.2105334174192019 0.8332513727413893 1.0 1.0 9 P40939 1 +Impaired visuospatial constructive cognition 0.3659770074364477 0.2104406043230859 0.8333238044384228 1.0 1.0 8 P00403 1 +Abnormality of vitamin a metabolism 0.3846627656298091 0.2098823740941499 0.8337594792774718 1.0 1.0 5 Q9Y3A5,Q13043,Q9NSD9,P61011 4 +Poor coordination 0.3680669661513262 0.2096571743695851 0.8339352524971182 1.0 1.0 11 Q9Y619 1 +Duplication of phalanx of hallux 0.6643076923076976 0.208795124488745 0.8346081775510941 1.0 1.0 2 Q8WVQ1 1 +Cloverleaf skull 0.6643076923076867 0.2087951244887265 0.8346081775511085 1.0 1.0 2 P16435 1 +Shield chest 0.383979210576421 0.2080721014361198 0.8351726702486317 1.0 1.0 5 P04066 1 +Stillbirth 0.3675993767430993 0.2080611398092894 0.8351812290785754 1.0 1.0 12 O75844 1 +Prolonged neonatal jaundice 0.3565298267661618 0.2078218643586922 0.8353680600313573 1.0 1.0 19 O15118,Q15904 2 +Abnormality of the odontoid process 0.3651091930005136 0.2077556798770138 0.8354197398101946 1.0 1.0 8 P16278 1 +Abnormality of alkaline phosphatase level 0.3365820561790694 0.207021139561545 0.8359933491271043 1.0 1.0 24 P06400,Q14739,Q8N511 3 +Oligohydramnios 0.284103752424277 0.2067564714380489 0.8362000523032624 1.0 1.0 32 Q9UHX1,P49366,P23786,Q969X5,Q15650 5 +Poor head control 0.3472640502977607 0.2063057527323427 0.8365520851626 1.0 1.0 69 Q10713,O75380,P00374,P06865,O43676,Q8N183,Q9P0J0,P17900,Q15650,Q9BU61,Q9NWM8,Q8TB37,Q9Y6M9,P07602,Q96CU9,P21912,O75306,Q9NQT5 18 +Abnormal vena cava morphology 0.362137718518722 0.2035923857687709 0.8386720438018136 1.0 1.0 7 P98175,Q7Z5J4 2 +Anencephaly 0.3624637647943057 0.2033606234485713 0.8388531746459482 1.0 1.0 16 Q8TAA9,O43505,O00192,Q92917 4 +Aplasia hypoplasia involving the skeletal musculature 0.3648988480274727 0.203333534593862 0.8388743461474384 1.0 1.0 9 O43505,Q9Y487 2 +Generalized myoclonic seizure 0.3045387711485255 0.203148999714091 0.8390185738957263 1.0 1.0 44 P16278,Q13510,P04062,P07602,Q9Y619 5 +Hypopigmentation of the skin 0.3141350599052614 0.1983180351124578 0.8427962419402273 1.0 1.0 50 Q6PGP7,Q96C86,Q86YV9,Q15437,Q15477,P53634,P50336,Q05086,Q8IZA0,O00192,P07602,P21912 12 +Opisthotonus 0.3346784855708105 0.1975622832954855 0.8433875466743146 1.0 1.0 24 P07602,P35637,P04062,P11117 4 +Abnormality of circulating adrenocorticotropin level 0.357942181399911 0.1972837142650161 0.8436055230346147 1.0 1.0 6 O00170,P10644,P16435 3 +Hashimoto thyroiditis 0.5291597609575617 0.1970333930575475 0.8438014060890775 1.0 1.0 3 Q15437 1 +Increased urine proteinogenic amino acid derivative level 0.6572307692307724 0.1969293094891109 0.8438828571157313 1.0 1.0 2 P48637 1 +Microcytic anemia 0.3627262718759165 0.1965354465300952 0.8441910913071828 1.0 1.0 9 Q9UBX3 1 +Abnormality of the crus of the helix 0.5281625115420171 0.1951334144869586 0.8452885043712797 1.0 1.0 3 Q9H5V9,Q7LGA3 2 +Abnormality of cartilage of external ear 0.5281625115420171 0.1951334144869586 0.8452885043712797 1.0 1.0 3 Q9H5V9,Q7LGA3 2 +Skeletal muscle hypertrophy 0.2981210818031199 0.1949092031438744 0.8454640293028153 1.0 1.0 41 O00754,Q10713,P16278,P04066,Q15437,P50570,Q05086,P10253,Q15056,O75648 10 +Aganglionic megacolon 0.3467063671184759 0.1939187515308164 0.8462395007975376 1.0 1.0 21 Q10713,P42892,Q96EK5,Q9H0F7,O00192 5 +Short palpebral fissure 0.3173868263670872 0.1929373610609943 0.8470080248151337 1.0 1.0 27 O75844,Q9Y619 2 +Diminished movement 0.3382628805162062 0.1923358147446223 0.84747916596918 1.0 1.0 23 P04062,Q709C8,P13473 3 +Acute coronary syndrome 0.3523905455501901 0.1904890023512044 0.8489259602639683 1.0 1.0 19 P06280,P01889,O75844,Q9NZ08,Q15056 5 +Multifocal seizures 0.3533579790511452 0.1843086585813377 0.8537713217225065 1.0 1.0 6 Q9UGM6,Q9HA77,Q6PJG6,Q10471,Q96S52 5 +Abnormal circulating albumin concentration 0.2959236355972242 0.1836861014743396 0.8542597128014093 1.0 1.0 30 Q6PGP7,O95470 2 +Episodic pain 0.3586146925234476 0.1782802085039623 0.8585029211443052 1.0 1.0 13 P23786,Q02978,P37287,P21359,P21912 5 +Nonimmune hydrops fetalis 0.3085521568369745 0.1782647236522274 0.858515081490546 1.0 1.0 28 P10619 1 +Panniculitis 0.3530756728360676 0.177245597268337 0.8593154811760726 1.0 1.0 7 P28070,P52732 2 +Abnormal hair laboratory examination 0.3567199872783016 0.174884678511562 0.8611702495137545 1.0 1.0 10 Q6PGP7,Q15477 2 +Gastrointestinal hemorrhage 0.3079477396905286 0.1748580106212295 0.8611912045473831 1.0 1.0 28 P49327,Q9UHX1,P21964,P01889,Q9NZ08,Q14739,O00192,P49257,P21912,P60866 10 +Dermal atrophy 0.3295472737428968 0.172537584766621 0.8630149160179943 1.0 1.0 24 O75844,Q15392,Q8NCH0,Q9NWM8 4 +Joint hemorrhage 0.6412307692307742 0.1718821234639184 0.8635302008294445 1.0 1.0 2 P49257 1 +Profound hearing impairment 0.3876231527093527 0.1716784617092935 0.8636903194571037 1.0 1.0 4 P35241,Q15046,P55011 3 +Spastic diplegia 0.3288036422666023 0.1689695596796549 0.8658205849443179 1.0 1.0 24 P07602,P51648,Q13509 3 +Optic nerve hypoplasia 0.3490288964010919 0.1668339708517123 0.8675006883920973 1.0 1.0 18 Q9UHX1,Q9Y6N7,Q9NVI7,Q13509,P37268 5 +Abnormality of vitamin e metabolism 0.3845443349753614 0.165235107161396 0.8687589335181709 1.0 1.0 4 Q9Y3A5,P61011,Q13043 3 +Abnormality of vitamin k metabolism 0.3845443349753614 0.165235107161396 0.8687589335181709 1.0 1.0 4 Q9Y3A5,P61011,Q13043 3 +Metaphyseal chondrodysplasia 0.3845443349753612 0.1652351071613952 0.8687589335181716 1.0 1.0 4 Q9Y3A5,O95831,P61011 3 +Omphalocele 0.3534441466761669 0.1623267588743898 0.8710485435892577 1.0 1.0 14 Q6DKJ4,Q96EX3 2 +Wormian bones 0.3474444729404229 0.1607103122876728 0.8723215669848807 1.0 1.0 18 O75844,O75718,Q32P28,Q9Y487 4 +Neoplasm of the larynx 0.3643363104404103 0.1592357275811212 0.8734831564209893 1.0 1.0 5 O96017,P52701,P42771,P43246 4 +Mandibular prognathia 0.2873443274191309 0.1579136986533843 0.8745248035409756 1.0 1.0 38 Q9UHX1,P16278,Q9NVI7,P10644,Q7Z5J4,Q05086,P52732,O00754 8 +Limb girdle muscle weakness 0.3105233270806233 0.1558752525235202 0.8761313524712766 1.0 1.0 27 O14979,O60313,Q8TD16,P07602,Q13126 5 +Recurrent paroxysmal headache 0.3503359266431177 0.1556193584413409 0.8763330650185219 1.0 1.0 10 P21912,P10644,Q02978,P00403 4 +Typical absence seizure 0.3492587507570869 0.1544243392822695 0.877275163862894 1.0 1.0 16 Q13510 1 +Duplication of the distal phalanx of hand 0.6283076923076847 0.1534519113581661 0.8780419102525787 1.0 1.0 2 Q8WVQ1 1 +Retinal detachment 0.3511098076990752 0.1534400227518395 0.87805128496883 1.0 1.0 13 P04439,Q7Z5J4,P52732,Q8NCH0,O43505 5 +Cyanosis 0.3454867814468364 0.1532220808196139 0.8782231452969431 1.0 1.0 18 O75844,P04066 2 +Aplasia hypoplasia of the capital femoral epiphysis 0.3402608839719825 0.1491899772846025 0.8814037284536356 1.0 1.0 6 Q8WVQ1,Q7LGA3,Q7RTS9 3 +Flat occiput 0.3460168345464835 0.148132132563012 0.8822384910617735 1.0 1.0 17 O00754,Q05086,Q13509,P52732 4 +Chest pain 0.3358176344074671 0.1469885352233589 0.8831410695934543 1.0 1.0 21 P31153,Q93063,P10644,P01889,P50336,P37287,P21912 7 +Metaphyseal irregularity 0.3471586512637059 0.1463129134899978 0.8836743720717344 1.0 1.0 10 Q7RTS9,Q96HY6,Q9NR45 3 +Limitation of movement at ankles 0.3584546955705003 0.1458420324404719 0.8840460935418579 1.0 1.0 5 O75844 1 +Aplasia hypoplasia of metatarsal bones 0.3463014810517258 0.1438347826438392 0.885630935871186 1.0 1.0 10 Q9Y366,P10644,Q7RTS9 3 +Stereotypical body rocking 0.6209230769230818 0.1436373996050334 0.8857868062589376 1.0 1.0 2 Q9H7D7 1 +Incoordination 0.3390887842813872 0.1430787836777837 0.886227960703827 1.0 1.0 70 Q01105,Q13510,Q6DKK2,P40939,O75503,O14773,P04062,Q9H0F7,P07602,Q9Y619 10 +Congenital malformation of the right heart 0.3444840628313637 0.1427275824059602 0.8865053321213652 1.0 1.0 9 O15460,P01889 2 +Limb tremor 0.3371771095525749 0.1413532325504115 0.8875908982392264 1.0 1.0 6 Q05086 1 +Coxa vara 0.3450701155157279 0.1396691954875775 0.8889213662328919 1.0 1.0 16 O75718,Q7RTS9,Q93063,Q96AY3,Q9Y487,Q8WVQ1,P50542,Q96HY6 8 +Abnormal circulating free fatty acid concentration 0.4941511693991754 0.1374276384367676 0.8906927859877596 1.0 1.0 3 P40939 1 +Renal tubular atrophy 0.3697660098522067 0.1363903220299282 0.8915127240865344 1.0 1.0 4 Q9NQH7,Q96AX1,P57740 3 +Hyperkeratotic papule 0.4933825792551599 0.1362829558700055 0.8915975974119121 1.0 1.0 3 Q6PD74,Q8NBL1 2 +Stage 5 chronic kidney disease 0.3007182963416724 0.1350562951913765 0.8925673648838401 1.0 1.0 28 P23786,O95470 2 +Abnormality of the gingiva 0.2975846434648236 0.1350138961500087 0.8926008873941085 1.0 1.0 46 O00754,P16278,P10644,Q6DKJ4,Q14108,P37287,Q15392,Q14739,P04062,Q15056 10 +Reduced vital capacity 0.6107692307692363 0.1309837238508062 0.8957881829529435 1.0 1.0 2 P06753 1 +Elevated tissue non specific alkaline phosphatase 0.6107692307692231 0.1309837238507905 0.8957881829529559 1.0 1.0 2 Q13043 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.4890735610957262 0.1299948809785485 0.8965704767127356 1.0 1.0 3 Q9NS87,Q9BXW9 2 +Attenuation of retinal blood vessels 0.3377493906997638 0.1297634968557581 0.8967535439573058 1.0 1.0 8 Q9H0F7 1 +Variable expressivity 0.3531073772680686 0.1293209250778088 0.8971037146428062 1.0 1.0 80 P35270,Q70HW3,P00403,Q13510,P17900,Q13509,Q9NQT5,Q9H061,P07602,P52732,O95470 11 +Poor motor coordination 0.3431786579946443 0.1285678061443875 0.8976996418123475 1.0 1.0 14 O75503,Q10713 2 +Exodeviation 0.3312349623386219 0.128125016098182 0.8980500392197495 1.0 1.0 21 Q9UHX1,Q8IYI6,Q13509,P40939,Q05086 5 +Dysphasia 0.338322380164559 0.1265716426501722 0.899279442279106 1.0 1.0 18 Q9H9P8,Q9UQN3,Q7Z5J4,O00192 4 +Blindness 0.3509205800882929 0.1257720235115344 0.8999123878883017 1.0 1.0 79 O43676,P50897,Q9Y6M9,Q9H0F7,P07602,Q96CU9,P16278,P06865,Q8N183,P49770,P52732,O75306,O43505,P17900,Q9H6K4,Q9NZ08,Q9BU61,Q8WWY3,O75380,Q9UI10,P01889,Q8TB37 22 +Retinal hemorrhage 0.3305386898771874 0.1250565801202972 0.9004787574103066 1.0 1.0 6 P50570,Q9Y487 2 +Broad based gait 0.3147891104576877 0.1247642529502274 0.9007101882217621 1.0 1.0 25 P98175,Q7Z5J4,Q05086,O14773,P04062 5 +Fatigue 0.353903191850717 0.1243572346094086 0.9010324322786114 1.0 1.0 81 P06280,Q70HW3,Q4J6C6,Q9UQN3,O15460,P10644,P01889,Q9NZ08,P04062,P02792,P07602,Q9UDY8,Q92804,P35637 14 +Acidemia 0.3414260955142466 0.1242970061602979 0.9010801176584248 1.0 1.0 12 P48735 1 +Abnormality of bladder morphology 0.3372438835343698 0.1230634590307187 0.9020568467506014 1.0 1.0 9 Q15056,Q9NWM8 2 +Specific learning disability 0.3290647975674799 0.1216993908387699 0.903137095692867 1.0 1.0 66 Q96DF8,P31150,Q10713,P00403,Q9UQN3,Q13509,P10644,P00367,P04350,Q9H6K4,Q96EK5,Q9H0F7,O00754,Q9Y619,O00192,P52732,O43505,P35637 18 +Recurrent bronchopulmonary infections 0.3467816445950124 0.1209849175105952 0.9037029815174628 1.0 1.0 5 Q9Y2Q5,Q96AX1,P18074,P19447 4 +Uric acid nephrolithiasis 0.6018461538461599 0.1206559988920581 0.9039635120889986 1.0 1.0 2 P07741 1 +Macroscopic hematuria 0.6018461538461599 0.1206559988920581 0.9039635120889986 1.0 1.0 2 P07741 1 +Polycystic kidney dysplasia 0.3382442778419402 0.1204620910836755 0.9041171078520048 1.0 1.0 17 P23786,O00192,Q6PGP7,Q15477 4 +Hydroxyprolinuria 0.6006153846153904 0.1192888298834733 0.9050465327714984 1.0 1.0 2 O00469 1 +Severely reduced visual acuity 0.5999999999999992 0.1186104144547868 0.9055840140609746 1.0 1.0 2 O15078 1 +Hypoplasia of the musculature 0.3454436259516377 0.1182835338301022 0.9058430039033344 1.0 1.0 5 Q9Y487 1 +Restrictive ventilatory defect 0.3387528080825311 0.1164987249634757 0.907257296550064 1.0 1.0 12 P16278 1 +Broad chin 0.5963076923076986 0.1146119475055479 0.90875270937865 1.0 1.0 2 P55011 1 +Olivopontocerebellar hypoplasia 0.3568349753694462 0.1139899633912402 0.9092457496366576 1.0 1.0 4 Q9UNW1,P30153,Q9H9S5 3 +Optic nerve dysplasia 0.477166115449966 0.1137521165899412 0.9094342975416604 1.0 1.0 3 O43505 1 +Bladder diverticulum 0.3286633265396587 0.1133962220221969 0.909716434783332 1.0 1.0 7 Q9NWM8 1 +Upper limb spasticity 0.3299175982411532 0.1099385120686741 0.912458139432746 1.0 1.0 8 P37287,Q12768,Q8N0X7,P35637 4 +Progressive sensorineural hearing impairment 0.3321893011336062 0.1099280040447818 0.9124664731127206 1.0 1.0 9 O60313,P00403 2 +Neoplasm of the male external genitalia 0.3354554964390309 0.1099150630694875 0.9124767363255532 1.0 1.0 11 P10644,P51809,Q01844 3 +Slurred speech 0.3337925874198083 0.1092812413565771 0.9129794247070864 1.0 1.0 10 P16278 1 +Abnormality of the inner ear 0.3336399316064459 0.1088784818588585 0.9132988741542698 1.0 1.0 10 Q9Y619 1 +Neonatal death 0.336437787554953 0.1081601725770129 0.913868637239728 1.0 1.0 13 Q9NVI7,Q14739,P04062 3 +Cutaneous melanoma 0.3525246305418613 0.1071093516383969 0.9147022283151232 1.0 1.0 4 P11802,P42771,P19447 3 +Talipes valgus 0.3388376463881655 0.1053945768980333 0.9160627191076812 1.0 1.0 5 O00754 1 +Increased susceptibility to fractures 0.3078974211931521 0.1042785478989182 0.9169483013867374 1.0 1.0 55 O15269,O75874,O75718,P07237,P10644,P48735,Q14108,Q14739,P04062,Q15650,Q32P28,Q13126 12 +Short thorax 0.3268693341610443 0.102536374836154 0.9183309420452356 1.0 1.0 8 Q9Y366,Q96EX3 2 +Decreased circulating acth level 0.4680333159267948 0.102404775776842 0.9184353930813864 1.0 1.0 3 P10644 1 +Hyperthyroidism 0.3301943388561834 0.0999113014488052 0.9204147439898588 1.0 1.0 10 O00192 1 +Abnormal enchondral ossification 0.2748863170640461 0.0993688656260709 0.920845402019906 1.0 1.0 31 Q7RTS9,O00116,P50542,P10644,Q8WVQ1,Q14739,Q9Y5Y5,Q96EX3,Q9Y619,Q96HY6 10 +Bilateral cryptorchidism 0.3256338208067074 0.0936318047856185 0.9254016440240668 1.0 1.0 9 P38606,P37268,P78318,P48449 4 +Toe walking 0.3160253677282593 0.0934465140278416 0.9255488393001172 1.0 1.0 23 P07602,O43681,P40939 3 +Abnormal tricuspid valve morphology 0.3289595008075852 0.0891979378759185 0.9289246041835586 1.0 1.0 12 Q6DKJ4,O00192,P21964 3 +Abnormal shape of the occiput 0.2659544078079206 0.0885366697668997 0.9294501405015696 1.0 1.0 32 P56589,Q9Y366,Q13509,P37287,Q12768,Q05086,Q04721,Q9Y5Y5,P52732,O00754,P50542 11 +Mildly elevated creatine kinase 0.314333099526645 0.0865012681863403 0.9310679479852088 1.0 1.0 23 P40939,Q92734,P50570,Q969X5,Q15650,O75648 6 +T cell lymphoma 0.3380541871921096 0.0861202769344891 0.931370804843942 1.0 1.0 4 P49327,P52701,Q07864 3 +Abnormality of hepatobiliary system physiology 0.3506020044303508 0.0854110075018362 0.9319346424209788 1.0 1.0 83 Q6PGP7,Q10713,Q8N511,Q13510,O15118,O43772,O15460,P23786,P40939,P01889,Q15833,P04062,Q9Y619,O75306 14 +Profound sensorineural hearing impairment 0.4524469067405404 0.0851969631580405 0.932104804853802 1.0 1.0 3 P35241,P55011 2 +Abnormality of the anterior fontanelle 0.2704690519804281 0.0843206683360453 0.9328014799641052 1.0 1.0 35 Q9Y619,Q32P28,Q9Y487 3 +Irregular vertebral endplates 0.3365147783251153 0.0840758050222488 0.9329961613152606 1.0 1.0 4 O15228,Q9NR45,Q14807 3 +Congenital malformation of the left heart 0.3365147783251125 0.0840758050222452 0.9329961613152636 1.0 1.0 4 Q12768,O60826,Q8N3U4 3 +Chronic neutropenia 0.3258392362180439 0.0822105502841108 0.9344792839330244 1.0 1.0 5 Q9Y3C6,Q9Y3A5,Q7Z2Z2,P61011 4 +Abnormality of circulating fibrinogen 0.3180663571580988 0.0821629303862864 0.9345171510084604 1.0 1.0 8 Q15833 1 +Abnormal ureter morphology 0.2958251436558281 0.0817414440635452 0.9348523210157048 1.0 1.0 27 O75844,P23786 2 +Abdominal pain 0.3498819498356959 0.0811962146383863 0.9352859098591144 1.0 1.0 83 P06280,Q70HW3,P42892,O15460,P23786,P01889,Q14108,P50336,Q9NZ08,P04062,Q9UDY8 11 +Chronic kidney disease 0.26985568435157 0.0806198141439215 0.9357443080882182 1.0 1.0 35 P23786,O95470,Q9UBS4 3 +Polar cataract 0.4467673105471511 0.0795804865014268 0.9365709155020115 1.0 1.0 3 P50542 1 +Shallow acetabular fossae 0.5572307692307703 0.079524839388873 0.9366151752006048 1.0 1.0 2 Q9ULC3 1 +Serositis 0.3228834007287397 0.0785240490050557 0.9374112009430716 1.0 1.0 19 Q9NZ08,O15460 2 +Hyperhidrosis 0.2642713623152456 0.0783350774394517 0.93756151541888 1.0 1.0 32 P35270,P04066,O15460,Q9UDY8,P51797,P01889,P21912,P61978 8 +Monocytosis 0.5550769230769301 0.0779534824490779 0.9378650559625464 1.0 1.0 2 P61011 1 +Abnormal monocyte morphology 0.5550769230769301 0.0779534824490779 0.9378650559625464 1.0 1.0 2 P61011 1 +Aplasia hypoplasia of the spleen 0.3227594702802581 0.0771388975457886 0.938513049404888 1.0 1.0 5 O15078,P08865,Q7L590,Q8TD19 4 +Unconjugated hyperbilirubinemia 0.3307715696961947 0.0767612703466237 0.9388134615795094 1.0 1.0 4 P37287 1 +Abnormal femoral neck morphology 0.2775993170394874 0.0753625059050428 0.9399262902951148 1.0 1.0 40 O75718,Q93063,Q7RTS9,P16278,P04066,Q9Y5S9,P50542,Q96AY3,Q9Y487,Q8WVQ1,O75844,Q9NR45,P46109,O00754,Q9Y619,Q96HY6 16 +Abnormal lactate dehydrogenase level 0.3175226459509455 0.0750494819609716 0.94017534195859 1.0 1.0 21 P06400,P23786,P10253,P41440,O43505 5 +Proximal femoral metaphyseal abnormality 0.4416743613419564 0.074830841232156 0.9403493028490506 1.0 1.0 3 Q9NUQ7,P61011 2 +Aplasia hypoplasia of the vagina 0.4411323628907385 0.0743410657319144 0.9407390016862602 1.0 1.0 3 P51809 1 +Irregular femoral epiphysis 0.4373653431825228 0.0710191290725698 0.9433825311323544 1.0 1.0 3 Q9NUQ7,P50542 2 +Eeg with abnormally slow frequencies 0.320451207247001 0.0702749143940774 0.9439748485461372 1.0 1.0 19 O75503,Q05086,Q9UQN3,Q05639 4 +Exaggerated cupid s bow 0.3049686964124304 0.0698017638725316 0.944351443237099 1.0 1.0 6 Q6DKJ4,P61978 2 +Agenesis of permanent teeth 0.5415384615384718 0.0688709881529137 0.9450923117695798 1.0 1.0 2 Q9ULC3 1 +Abnormal number of permanent teeth 0.5415384615384718 0.0688709881529137 0.9450923117695798 1.0 1.0 2 Q9ULC3 1 +Flattened femoral epiphysis 0.5412307692307781 0.068680030182323 0.945244314269124 1.0 1.0 2 Q9NUQ7 1 +Abnormal circulating dicarboxylic acid concentration 0.2814212065116759 0.0675803816505629 0.9461196728646613 1.0 1.0 43 P22695,P23786,P48735,P37268,Q14739,P41440,Q9H9P8,O75648 8 +Autism 0.2829794237010745 0.0667068567231976 0.946815075597476 1.0 1.0 44 Q93063,P21964,Q15056,P10644,Q05639,Q15437,Q7Z5J4,Q05086,O00192,P21912,Q9NVH6,Q9UET6 12 +Focal tonic seizure 0.5369230769230858 0.0660762048105655 0.9473171552510192 1.0 1.0 2 Q9H936 1 +Stomatitis 0.3194921537452768 0.0647428495514448 0.9483787453602376 1.0 1.0 12 P49327,P10644,P01889,Q9NZ08 4 +Aplasia hypoplasia affecting the fundus 0.3088699383179809 0.0646796889527149 0.948429034821722 1.0 1.0 23 Q9UHX1,Q9Y6N7,Q9NVI7,Q86YV9,Q13509,P37268 6 +Neonatal onset 0.3198240004366323 0.0635400994723868 0.94933642897675 1.0 1.0 18 P40939 1 +Tonic seizure 0.2918696838034622 0.0631096511450573 0.9496791891183716 1.0 1.0 27 P07602 1 +Biconcave vertebral bodies 0.3055225686323727 0.0630476684091052 0.949728545895408 1.0 1.0 7 Q9NR45,Q96AY3,Q04721 3 +Cerebellar cortical atrophy 0.427516158818103 0.062995620541395 0.9497699916979736 1.0 1.0 3 O75845,O75312 2 +X linked recessive inheritance 0.2973299984472173 0.0615253293519011 0.9509408427081364 1.0 1.0 53 P06280,Q9Y4W2,O15344,P98175,Q15904,P11413,P46020,P37287,P78318,Q9H0F7,Q14320,Q9NVH6,Q9UET6 13 +Hypoplastic helices 0.5280000000000111 0.0610840290262668 0.9512922883881316 1.0 1.0 2 Q9UDR5 1 +Cerebral white matter atrophy 0.3077081992375101 0.0601594128910561 0.9520286709565712 1.0 1.0 23 O75503,O60313,Q9H9P8,O00754 4 +Neoplasm of the skeletal system 0.2799192749123512 0.0588209928754966 0.9530946875122508 1.0 1.0 43 O75874,P06400,P10644,P48735,Q92804,P62857,Q13126 7 +Macroorchidism 0.3137315270935895 0.0578724153027851 0.9538502556840835 1.0 1.0 4 Q9BZI7,P21359,P38159 3 +Lumbar hyperlordosis 0.3188774296914548 0.0577742777166001 0.953928427354575 1.0 1.0 17 Q7RTS9,Q9H9S5,P04066,P06753,Q96J02,Q06210,P41227,Q96HY6 8 +Neurofibromas 0.3128594073338479 0.057014780420692 0.9545334212205454 1.0 1.0 4 P21912 1 +Urticaria 0.3120599833414211 0.0566819586581916 0.9547985458123188 1.0 1.0 10 P51648,P21912 2 +Posterior embryotoxon 0.3098157079660081 0.0566249950496719 0.9548439233154242 1.0 1.0 22 Q96DF8,P56589,P21964,Q04721,Q9Y5Y5,Q15056,P50542,O00192 8 +Abnormal aldolase level 0.4114771056642674 0.0518644342498189 0.958636713473517 1.0 1.0 3 O43505 1 +Female infertility 0.4107576662584661 0.0514181520123246 0.9589923206905736 1.0 1.0 3 Q15645 1 +Abnormal urine alpha ketoglutarate concentration 0.2993813673163668 0.0513968325869251 0.9590093086687856 1.0 1.0 7 P00367 1 +Limb dysmetria 0.4093693009792684 0.0505692413203803 0.9596687733236802 1.0 1.0 3 Q12768 1 +Dyscalculia 0.3084068608713331 0.0487914955054567 0.961085459707457 1.0 1.0 10 Q9UQN3 1 +Acromesomelia 0.497538461538465 0.0477233684918973 0.961936709955678 1.0 1.0 2 Q9NS87 1 +Localized osteoporosis 0.496000000000005 0.047184059034435 0.9623665324186108 1.0 1.0 2 P82650 1 +Abnormal choroid plexus morphology 0.2969350597994763 0.0469559995847245 0.9625482960638698 1.0 1.0 7 Q8IYI6 1 +Spina bifida occulta 0.3132469782449103 0.0467765199141286 0.9626913429381398 1.0 1.0 19 Q9UHX1 1 +Reticular hyperpigmentation 0.4932307692307828 0.0462428966048418 0.963116652479212 1.0 1.0 2 P09884 1 +Erythematous papule 0.4932307692307767 0.0462428966048399 0.9631166524792134 1.0 1.0 2 Q8NBL1 1 +Abnormal tongue morphology 0.3227342909832401 0.0458411469968027 0.9634368627050196 1.0 1.0 70 O00754,Q10713,P16278,P04066,P98175,O15460,Q15437,P01889,Q6DKJ4,O75844,Q05086,P10253,Q96EX3,Q9Y5Y5,P46109,Q15056,Q9NQT5,O75648 18 +Dysuria 0.3001271446376666 0.0453180312217397 0.963853815366325 1.0 1.0 8 O00170,P01889,Q8N0X7 3 +Calcific stippling 0.3998153277931725 0.045154592067564 0.963984087586138 1.0 1.0 3 P50542,P51659 2 +Abnormality of hair texture 0.2910905073337875 0.0451058180193682 0.9640229640354714 1.0 1.0 51 P15586,P54802,P04080,Q6PGP7,Q9NVI7,Q9Y487,O75844 7 +Short proximal phalanx of finger 0.4889230769230815 0.0448524632611195 0.9642249075033428 1.0 1.0 2 Q9NS87 1 +Renal hypoplasia 0.2669762783630688 0.0435442029445671 0.9652677290674004 1.0 1.0 37 Q9UHX1,Q6PGP7,Q96EX3 3 +Thick corpus callosum 0.396121883656515 0.0432535030394213 0.9654994557059632 1.0 1.0 3 O00459,Q7LBC6 2 +Acute hepatic failure 0.3132220713414773 0.0431913672293544 0.96554898662156 1.0 1.0 14 P40939,P01889 2 +Abnormality of hair pigmentation 0.2959929012986927 0.0422573115704985 0.9662935752988252 1.0 1.0 25 Q6PGP7,P10644,Q15477,Q05086,P37268,Q13126 6 +Bulbar palsy 0.3051222635650086 0.0419329713129661 0.9665521321985776 1.0 1.0 10 O43681 1 +Motor regression 0.4738461538461517 0.0406419457097935 0.967581343924526 1.0 1.0 2 P51659 1 +Palmar pits 0.3890427823945871 0.0398922040984746 0.9681790663855636 1.0 1.0 3 Q9H488,Q8NBL1 2 +Hypergranulosis 0.389042782394587 0.0398922040984743 0.9681790663855638 1.0 1.0 3 Q6PD74,Q8NBL1 2 +Abnormality of upper limb metaphysis 0.3887349953831995 0.0397542020864056 0.9682890887840944 1.0 1.0 3 Q9H1A4,P26373 2 +Short columella 0.388119421360424 0.0394801827342639 0.9685075530843028 1.0 1.0 3 P49711,P41227 2 +Agammaglobulinemia 0.3865804863034831 0.0388066204387509 0.9690445664653252 1.0 1.0 3 O14920,Q9NRZ9 2 +Verrucae 0.3865804863034827 0.0388066204387506 0.9690445664653256 1.0 1.0 3 P16615,Q13043 2 +Streak ovary 0.295041576840157 0.0385699026556298 0.9692332986310236 1.0 1.0 5 O75616,P82650,P51809,P57740 4 +Pierre robin sequence 0.2964407236402641 0.0385265912259033 0.969267830485968 1.0 1.0 8 Q96DF8 1 +Erythroid hyperplasia 0.290640394088659 0.0384736689006792 0.9693100251088888 1.0 1.0 4 P37287,O75533,Q86SX6 3 +Ovarian carcinoma 0.2944256236525993 0.037852957268873 0.9698049208048604 1.0 1.0 5 Q5HYI8,P42771,P04637,P38398 4 +Extrahepatic cholestasis 0.2944256236525993 0.037852957268873 0.9698049208048604 1.0 1.0 5 Q5HYI8,P42771,P04637,P38398 4 +Functional intestinal obstruction 0.2944256236525993 0.037852957268873 0.9698049208048604 1.0 1.0 5 Q5HYI8,P42771,P04637,P38398 4 +Peritoneal abscess 0.2944256236525993 0.037852957268873 0.9698049208048604 1.0 1.0 5 Q5HYI8,P42771,P04637,P38398 4 +Abnormal heart valve morphology 0.32940406067351 0.0377520332149617 0.9698853890330086 1.0 1.0 75 P06280,Q7Z5J4,Q6DKJ4,P31153,Q6ZXV5,P16278,Q9UBS4,P37268,Q15056,P55795,P21964,Q15477,O75844,P04062,O00192,Q8NCH0,Q9UHX1,Q6PGP7,P10644,P01889 20 +Abnormal vagina morphology 0.3113224086876344 0.0375228666611112 0.9700681080241168 1.0 1.0 18 Q96EX3 1 +Delayed social development 0.3801304917004335 0.0361571315870425 0.9711570676583736 1.0 1.0 3 Q13509 1 +Decreased methylcobalamin 0.4516923076923114 0.036052384108925 0.9712405895985036 1.0 1.0 2 Q99707 1 +Progressive visual field defects 0.4498461538461591 0.035743428082443 0.9714869420576342 1.0 1.0 2 P35222 1 +Congenital bilateral hip dislocation 0.4464615384615408 0.0352031148624674 0.9719177784711746 1.0 1.0 2 Q9Y4R8 1 +Proximal femoral metaphyseal irregularity 0.4415384615384786 0.0344748511077509 0.9724984963329416 1.0 1.0 2 P61011 1 +Suicidal ideation 0.3751923668821228 0.034309959749033 0.9726299828155492 1.0 1.0 3 P42858,Q14203 2 +Progressive pes cavus 0.2841511524102057 0.0341758474527576 0.972736926228034 1.0 1.0 4 O00400 1 +Anophthalmia 0.3009087305779572 0.0334619581661385 0.9733062018173452 1.0 1.0 10 Q9H9S5,P41227,O15078,O75569,P52732,O43505 6 +Cone cone rod dystrophy 0.4332307692307669 0.0333894869843431 0.9733639931608457 1.0 1.0 2 Q6P4Q7 1 +Pancreatic fibrosis 0.4270769230769208 0.0326914939111396 0.9739206071427672 1.0 1.0 2 O15078 1 +Abnormality of amino acid metabolism 0.4230769230769187 0.0322819083718192 0.9742472367130552 1.0 1.0 2 P18074 1 +Flat nasal alae 0.4230769230769187 0.0322819083718192 0.9742472367130552 1.0 1.0 2 P18074 1 +Abnormal chromosome morphology 0.4209230769230776 0.0320748714257805 0.9744123427939446 1.0 1.0 2 Q6NZY4 1 +Reduced forced expiratory volume in one second 0.420923076923078 0.0320748714257805 0.9744123427939446 1.0 1.0 2 Q96J02 1 +Pulmonary artery stenosis 0.3097041412694648 0.031276807222543 0.97504878651255 1.0 1.0 16 Q15056,Q6PGP7,Q15477,Q04721 4 +Myoclonic seizure 0.3002952071702967 0.0310575466133043 0.975223646217736 1.0 1.0 58 Q01105,Q8IYI6,P16278,Q13510,Q96N66,O75503,P37287,Q8WWV3,P04062,Q9UPT5,P07602,Q9Y619,P21912,Q9UBB6 14 +Choroid plexus carcinoma 0.364112034472151 0.0306930154475553 0.975514361405261 1.0 1.0 3 O96017,P42771 2 +Choriocarcinoma 0.364112034472151 0.0306930154475553 0.975514361405261 1.0 1.0 3 O96017,P42771 2 +Abnormality of fontanelles 0.2834127500785446 0.0304892406078004 0.9756768741446062 1.0 1.0 48 O75718,P98175,Q9Y487,P37287,O75844,Q32P28,Q9Y619,Q8NCH0 8 +Acute kidney injury 0.2876501385894633 0.0303495678175513 0.9757882653581142 1.0 1.0 5 P37287,P07741,P00338,P00492 4 +Deviated nasal septum 0.3960000000000008 0.03026277147572 0.9758574870230728 1.0 1.0 2 P21359 1 +Fragile nails 0.3021016441420131 0.0300529152838423 0.976024851912138 1.0 1.0 11 Q9Y487,P02792 2 +Gastrointestinal stroma tumor 0.3613091564319792 0.0298857294282278 0.97615818703336 1.0 1.0 3 P21912 1 +Rotary nystagmus 0.2767857142857029 0.0298490617746687 0.9761874305416034 1.0 1.0 4 Q5T8D3,Q14738,Q9Y4R8 3 +Nocturnal seizures 0.3750769230769213 0.0293721671648941 0.9765677706088196 1.0 1.0 2 Q9NQX3 1 +Midline defect of the nose 0.37353846153846 0.0293233226342589 0.9766067261260752 1.0 1.0 2 P21359 1 +Abnormal circulating dehydroepiandrosterone concentration 0.3639999999999945 0.0290610830282845 0.9768158739230486 1.0 1.0 2 Q13423 1 +Adrenocorticotropic hormone deficiency 0.3639999999999973 0.0290610830282845 0.9768158739230486 1.0 1.0 2 O00170 1 +Ketotic hypoglycemia 0.3621538461538406 0.0290176780958826 0.9768504914491634 1.0 1.0 2 Q13423 1 +Cholangitis 0.3541538461538392 0.0288533995324436 0.9769815119175196 1.0 1.0 2 Q96J02 1 +Truncal titubation 0.3565215905596323 0.0285999942228485 0.977183616693158 1.0 1.0 3 Q5T8D3 1 +Long penis 0.3363076923076865 0.0285996811932559 0.9771838663525116 1.0 1.0 2 O00170 1 +Hyperplasia of the maxilla 0.3326153846153762 0.0285623809358237 0.9772136154988752 1.0 1.0 2 Q9H7D7 1 +Homocystinuria 0.327384615384606 0.0285165545747009 0.9772501647571508 1.0 1.0 2 Q99707 1 +Thin lower lip vermilion 0.3166153846153746 0.0284438746632213 0.9773081314225832 1.0 1.0 2 Q7LGA3 1 +Abnormal atrioventricular valve morphology 0.2589948890188109 0.0277190176375337 0.9778862556495518 1.0 1.0 34 P55795,Q9UBS4,Q6DKJ4,O75844,P04062,Q15056,O00192 7 +Cardiac diverticulum 0.2724753694581189 0.027572917043049 0.9780027825188872 1.0 1.0 4 P52701,P60866,P43246 3 +Ulnar deviation of finger 0.279728897104136 0.0271383654765597 0.9783493747947802 1.0 1.0 6 P46109,Q9Y3E5,Q9H2M9,P28482,Q15042 5 +Mild microcephaly 0.279433538422669 0.0267080445147767 0.9786925968274008 1.0 1.0 6 Q05086 1 +Abnormal mean corpuscular hemoglobin concentration 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Increased mean corpuscular hemoglobin concentration 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Bronchospasm 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Abnormal bronchus physiology 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Numerous pigmented freckles 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Defective dna repair after ultraviolet radiation damage 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Concave nail 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Tiger tail banding 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Low set nipples 0.3465681748230271 0.0262759573598791 0.979037231536494 1.0 1.0 3 P18074,P19447 2 +Sudden death 0.295370400112205 0.0257050318130568 0.9794926103779852 1.0 1.0 24 O15460,P0DP25,P40939 3 +Overriding aorta 0.2887714458725621 0.0252443875594423 0.9798600320722304 1.0 1.0 8 Q7Z5J4 1 +Iron deficiency anemia 0.2653940886699423 0.0242167960827757 0.980679680722448 1.0 1.0 4 P49327,Q10471,O76031 3 +Excessive salivation 0.2730584385978439 0.0238329107348542 0.98098588852945 1.0 1.0 29 P15586,P55795,P31150,P01889,Q05086,Q9UET6,Q8N0X7 7 +Short palm 0.294584934475704 0.0227766603635368 0.981828425526432 1.0 1.0 24 Q9UHX1,P10644,Q7Z5J4,Q9Y619,Q96EX3 5 +Abnormal b cell subset distribution 0.326206117530699 0.0227716104828968 0.9818324537034636 1.0 1.0 3 P17812 1 +Decreased specific antibody response to vaccination 0.3228685749461427 0.0223321263228012 0.9821830221681236 1.0 1.0 3 P50851,P17812 2 +Repetitive compulsive behavior 0.3136349646044989 0.0212808383954133 0.9830216291237202 1.0 1.0 3 Q01082,Q9H7D7 2 +Abnormality of corneal thickness 0.3051425910465086 0.0211150389923192 0.9831538881886716 1.0 1.0 15 Q9H0F7,Q8WWY3,Q10567 3 +Epidermoid cyst 0.30040012311481 0.0201354965266152 0.98393528374631 1.0 1.0 3 Q9H488,Q8NBL1 2 +Chronic oral candidiasis 0.3000923361034219 0.0201132351150576 0.9839530421865328 1.0 1.0 3 P02786,O00203 2 +Elevated circulating follicle stimulating hormone level 0.254743229469817 0.0199910927917049 0.9840504780695648 1.0 1.0 4 P16435 1 +Macular thickening 0.2741193041877562 0.0192312535007554 0.9846566255211348 1.0 1.0 6 Q8WWY3 1 +Psychotic episodes 0.264696829793788 0.0185033741714644 0.985237285827659 1.0 1.0 3 Q99497,Q5JRX3 2 +Laryngeal stenosis 0.2579255155432499 0.0183501493441932 0.9853595207976192 1.0 1.0 3 Q14807,Q96HY6 2 +Talipes equinovalgus 0.2579255155432496 0.0183501493441932 0.9853595207976192 1.0 1.0 3 O94766,Q9Y3E5 2 +Decreased fertility in females 0.2789148554481925 0.0177197318232865 0.9858624394000112 1.0 1.0 7 O00170,Q15645,P51809 3 +Gonadal dysgenesis 0.2955877815488992 0.0172109244827831 0.9862683470037644 1.0 1.0 11 P51659,P57740,Q96GM8,P26639,P18074,P19447,P51809,P82650,Q96RR1,Q9UNW1 10 +Pectus carinatum 0.2585214140342334 0.0156425623815031 0.9875195499595282 1.0 1.0 35 P55795,Q7RTS9,P16278,Q9NVI7,Q96AY3,Q6DKJ4,Q04721,O00754,Q9Y619 9 +Pulmonary hypoplasia 0.2810992661284275 0.0154344270224764 0.9876855979018356 1.0 1.0 27 Q8TAA9,P98175,O75844,Q15650,Q96EX3 5 +Neoplasm of the tongue 0.2355295566502378 0.0144862814465112 0.9884420239365376 1.0 1.0 4 P49327,Q8NCM8,P08754 3 +Papilloma 0.2905505254327087 0.0141953305001384 0.9886741453336592 1.0 1.0 10 P21912,Q15437,Q13043 3 +Facial hemangioma 0.2694795195565106 0.0135281884681046 0.9892063965129556 1.0 1.0 5 Q12768,O60826,P16435,Q9UBM7 4 +Progressive night blindness 0.301426148493105 0.012318798185886 0.9901712697100024 1.0 1.0 15 Q8WWY3,Q10713,Q9H0F7 3 +Delayed ability to sit 0.3021019727576483 0.0111298065887811 0.9911198824923342 1.0 1.0 17 P10253,Q10713 2 +Abnormal oral frenulum morphology 0.2948290660273452 0.0102246418754007 0.9918420582511542 1.0 1.0 12 Q6DKJ4,O75844 2 +Myoclonus 0.3616890937157586 0.0071654175574799 0.9942828728818314 1.0 1.0 99 Q01105,P04080,Q10713,P00403,Q13510,P05067,Q9UBX3,P50897,O75503,Q14108,O14773,P04062,P02792,P07602 14 +Spinal cord compression 0.2580843855866921 0.005234005822879 0.9958238866300916 1.0 1.0 5 O60333,P51530,Q9UNW1,Q93063 4 +Papilledema 0.2996759680142881 0.004992091725463 0.9960169036299256 1.0 1.0 17 P04062 1 +Abnormal uvula morphology 0.2667108651585189 0.0044064462328737 0.9964841759604426 1.0 1.0 41 Q9Y619,Q6PGP7 2 +Abnormality of the endometrium 0.2800891156228219 0.0040713436672453 0.9967515467204916 1.0 1.0 9 Q15437 1 +Abnormal tricuspid valve physiology 0.2976084096686949 0.0033023748829829 0.9973650908561316 1.0 1.0 20 P40939,Q15904 2 +Enlarged thorax 0.2979051522340838 0.0019502217044792 0.9984439491982248 1.0 1.0 16 Q7RTS9,P04066,O75844,Q14739,Q32P28 5 +Atonic seizure 0.288767262725604 0.0017584543906279 0.9985969571139146 1.0 1.0 24 Q13510 1 +Premature loss of teeth 0.2922149172115479 0.0001333687159346 0.9998935871609772 1.0 1.0 13 O75844 1 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9339fd4b6643c5557e19de6ada486b9f8ad75a13 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal haptoglobin level", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of olfactory lobe morphology", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of venous physiology", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Biconvex vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Budd chiari syndrome", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Conjunctival icterus", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Coronary artery stenosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal symphalangism", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spondylometaphyseal dysplasia", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATRIP", "ATXN10", "AURKA", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCKDHA", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BUB1B", "BUB3", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CAPN5", "CARS", "CARS2", "CASK", "CAST", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CD320", "CD3EAP", "CDC42", "CDC73", "CDH2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CELF2", "CENPE", "CENPF", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIT", "CIZ1", "CLASP1", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COG2", "COG4", "COG5", "COG7", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRAT", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CUL7", "CUX1", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPYSL5", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAH", "FAM126A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALNS", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGA2", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IKBKB", "IMPA1", "IMPAD1", "INF2", "INTS1", "IRS4", "ISCU", "ITCH", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "L2HGDH", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LMAN1", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LZTFL1", "MACF1", "MAGED2", "MALT1", "MAN2B1", "MANBA", "MAP1B", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED23", "MESD", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NEMF", "NF1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PCNT", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "ROBO1", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RREB1", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCP2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLTM", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRC", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STX16", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAOK1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMMDC1", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1A", "TOR1AIP1", "TP53", "TP53RK", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", 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sha256:8933daa77a7bbf53a233efc5999bc1703b89c7949f2d92dff69dfd5fe632f62d +size 142862 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..db3e422d088fb916bca54cf2a2cbb25244cc8a34 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6060e5404dd86cd91eda49747389a3532318a6acda6c16dd9cdef23bf479c8c +size 76423 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..38497f621fc1a488176908d0b59ec420e0c8a477 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 35 49 3.742985441396719 0.0001818467686407 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 4.280275547332214e-18 4.04168772494706e-07 1.6368462204970788e-10 2.1317644776983746e-21 2.0370784953650445e-18 +Other glycan degradation 6 8 2.458444205438924 0.0139540457356219 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 1.02651962512247e-07 1.0 0.1277572387780678 5.090864628783262e-07 1.6398016817489326e-06 +Glycosaminoglycan degradation 3 6 2.447075314875302 0.0144020740564194 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 5.144643156630706e-05 0.0561990347849709 0.0057815105752346 0.0001472775053537 0.0020484591711739 +Sphingolipid metabolism 7 10 2.3404174495555696 0.0192621961794345 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 5.102185784534777e-06 0.0063255491406275 9.045443106927394e-05 2.394767280194813e-05 1.6075753810838207e-05 +Proteasome 14 35 1.990603125816315 0.0465245363433219 10.895631067961164 35.30825242718446 0.6639562464102341 0.4930746972205201 6.290791570409542 1.0118856061679289 1.2857516091435552 0.3675316845524202 0.0057740732300209 0.1715759324473242 0.006299868694297 0.0024377113202794 0.000499223363328 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3cda605d1d60be4e87178addfcf55d2b388abd5b --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 16.519553072625698 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2cb55dc848e1dbf6784e9f58c963a597edc62542 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..89e7b134a8717cd568ba22f554d2f5e5ae63abdd --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,70 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.7805578210830445 3.7429854413967183 0.0001818467686407 0.0320293685274498 0.032550571586694 49 P06280,Q10567,O15118,P04066,Q92572,Q15904,P53634,P50897,P10253,P20645,P07602,P15586,Q9UMR5,Q8NCC3,P16278,P06865,Q13510,P10619,O75503,O14773,P11717,P61916,P17900,Q9Y487,P11117,Q14108,P04062,O00754,Q93050,P54802,P11279,O43681,O00462,P61966,P13473 35 +Other glycan degradation 0.8894569630570728 2.4584442054389237 0.0139540457356219 0.9191666012887468 0.6783019306387728 8 P16278,P04066,P06865,P04062,Q9BTY2,O00462 6 +Glycosaminoglycan degradation 0.9006497632600902 2.447075314875302 0.0144020740564194 0.9254820699698324 0.6783019306387728 6 P54802,P15586,P16278 3 +Sphingolipid metabolism 0.8457975998619203 2.3404174495555696 0.0192621961794345 0.9692410166692588 0.6783019306387728 10 P06280,P16278,Q13510,O43681,P04062,Q06136,O95470 7 +Glycosphingolipid biosynthesis ganglio series 0.8806187793740927 2.055205469087836 0.0398591631144824 0.9993114197812556 0.6783019306387728 4 P16278,P06865 2 +Proteasome 0.5082717054597939 1.990603125816315 0.0465245363433219 0.999802118879337 0.6783019306387728 35 P62333,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 14 +Renin angiotensin system 0.833212805194768 1.8614781427880545 0.062676684453073 0.9999907059245992 0.6783019306387728 4 P10619 1 +Glutathione metabolism 0.6576261818485292 1.836021623459292 0.0663544586717572 0.9999954018521428 0.6783019306387728 19 O75874,O15217,O95881,P19623,P48735 5 +Allograft rejection 0.8035714285714257 1.738776151377974 0.0820741450789543 0.9999997799299832 0.6783019306387728 4 P04439,P01889,P10321 3 +Graft versus host disease 0.8035714285714257 1.738776151377974 0.0820741450789543 0.9999997799299832 0.6783019306387728 4 P04439,P01889,P10321 3 +Autoimmune thyroid disease 0.8035714285714257 1.738776151377974 0.0820741450789543 0.9999997799299832 0.6783019306387728 4 P04439,P01889,P10321 3 +Porphyrin and chlorophyll metabolism 0.700194169201362 1.7165307879448877 0.0860649379125826 0.9999998991105729 0.6783019306387728 11 P30519,P09601 2 +Calcium signaling pathway 0.6407641403042614 1.598629810525069 0.1099028818597709 0.9999999991101972 0.7566390712653459 16 P0DP25,P45880,P21796,P46020 4 +Glycosphingolipid biosynthesis globo series 0.927079363611728 1.512035415781277 0.1305248531506322 0.9999999999866022 0.8056534039297645 3 P06280 1 +Riboflavin metabolism 0.6626827579060077 1.4433401106990276 0.1489246858661921 0.9999999999997088 0.8322101779406826 6 Q9NPH0 1 +Vibrio cholerae infection 0.5664358167008086 1.4311166418311427 0.1523967885116426 0.99999999999986 0.8322101779406826 21 P24390,Q9Y487,O43731,Q15904 4 +Galactose metabolism 0.6281469505693549 1.427540282323646 0.1534242227488409 0.9999999999998872 0.8322101779406826 13 P06280,P10253,P16278 3 +Folate biosynthesis 0.8805786395814105 1.3344920579437989 0.1820426479750048 0.9999999999999998 0.9584009996331136 3 Q92820,P35270 2 +Snare interactions in vesicular transport 0.6087162513715095 1.3043546838576672 0.1921126784465348 1.0 0.982519126912278 12 O60499,Q9P2W9,O15498,Q13190 4 +Regulation of autophagy 0.6081646940438903 1.2015181422814236 0.2295502732843051 1.0 1.0 6 Q6PHR2,Q9NT62,P60520,Q9Y4P1 4 +Type i diabetes mellitus 0.6415129382375409 1.19499067776945 0.2320906723733795 1.0 1.0 5 P04439,P10321,P01889 3 +Ether lipid metabolism 0.6700267594376381 1.1766933366701011 0.2393179283772557 1.0 1.0 4 O00116,Q15102 2 +Abc transporters 0.5892296360519 1.1378638646222805 0.2551773322045028 1.0 1.0 8 P33527,Q9NUT2,P08183 3 +Cell adhesion molecules cams 0.5849596173617947 1.1317665491790665 0.257732594554259 1.0 1.0 9 P04439,P10321,P01889,Q9Y624,Q92896 5 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8236858112278502 1.1183682946314295 0.2634097296682767 1.0 1.0 3 Q8N6G5 1 +Parkinsons disease 0.4287702229672969 1.0037082919143232 0.3155192391360384 1.0 1.0 56 P14406,O75380,P21796,P00403,O43676,Q9UDW1,P45880,P24539,O95168,O95182,Q9Y6M9,O75306 12 +Arachidonic acid metabolism 0.6204481426584131 0.9688156814448824 0.332637161067618 1.0 1.0 4 P09960,Q9H7Z7 2 +Cardiac muscle contraction 0.478322232829423 0.9066861115508338 0.3645728099060692 1.0 1.0 21 P14406,Q9UDW1,P67936,P00403 4 +Biosynthesis of unsaturated fatty acids 0.5333402129785878 0.903893405912611 0.3660519260418193 1.0 1.0 10 Q9NZ01,Q53GQ0,P40939 3 +O glycan biosynthesis 0.7440787289247666 0.8239563508695306 0.4099643599040781 1.0 1.0 3 O43505 1 +Glycosaminoglycan biosynthesis heparan sulfate 0.7436134195136987 0.8222837096740171 0.4109154459405384 1.0 1.0 3 O94766,Q93063 2 +Pancreatic cancer 0.4817850294941364 0.7374569576868942 0.4608445090552124 1.0 1.0 15 P11802,O14920,P40763,P06400,O00459,P42771,P42224,P11233,Q00534 9 +Antigen processing and presentation 0.476685189784913 0.7336226875345302 0.4631787296786502 1.0 1.0 16 P04439,P10321,Q9UL46,P08238,Q03518,P01889,P61289 7 +Oxidative phosphorylation 0.3797861773458273 0.5525790047387522 0.5805517218439471 1.0 1.0 60 P14406,O75380,P00403,O43676,Q9UDW1,Q9Y487,O75964,Q15904,O95168,O95182,Q9Y6M9,Q93050,O75306 13 +Glycerolipid metabolism 0.4352835174446195 0.484444180153603 0.628070670382632 1.0 1.0 13 P06280,Q9HCL2 2 +Bladder cancer 0.4653160811096104 0.4680747743245697 0.6397311179437932 1.0 1.0 5 P06400 1 +Alzheimers disease 0.3670273778418862 0.4678318357922852 0.6399048522150763 1.0 1.0 59 P14406,O75380,P00403,O43676,Q9UDW1,P05067,O95168,P0DP25,Q92542,Q9Y6M9,O95182,O75306 12 +Notch signaling pathway 0.4287146769452756 0.433769635616314 0.6644557334159291 1.0 1.0 7 P56545,Q04721,Q92542 3 +Steroid biosynthesis 0.4273200021962813 0.4309345064234109 0.6665159924615938 1.0 1.0 10 Q16850,Q15392,P37268 3 +Long term depression 0.4266688734105884 0.4251501821321125 0.6707271979023486 1.0 1.0 8 P30154,P30153 2 +Limonene and pinene degradation 0.4156366411691942 0.3826461873490902 0.701982119305933 1.0 1.0 8 P40939 1 +Proximal tubule bicarbonate reclamation 0.3945694617891067 0.3054351333503015 0.7600347668379086 1.0 1.0 8 Q9UBX3 1 +Fc epsilon ri signaling pathway 0.3914462769636019 0.2944767577668566 0.7683936210913327 1.0 1.0 8 Q16539 1 +Huntingtons disease 0.3748011327356609 0.2815497377854621 0.7782887849601356 1.0 1.0 79 P14406,O75380,P21796,P00403,O43676,P61218,Q9UDW1,P45880,P24539,O95182,O95168,Q9Y6M9,O75306 13 +Starch and sucrose metabolism 0.3846453725802469 0.2724582835114402 0.7852696632493172 1.0 1.0 13 P10253 1 +Prostate cancer 0.3812943653762713 0.2705751981358961 0.7867177734971087 1.0 1.0 15 O15111,P08238,P07900,O14920,P06400,O00459,P49841,P62993,P42345,P31751,P14625,P35222,P24941 13 +Gnrh signaling pathway 0.3826739440975216 0.2605177145600927 0.7944644526987399 1.0 1.0 10 P0DP25 1 +Small cell lung cancer 0.380085758027502 0.2524161999228113 0.8007193797341097 1.0 1.0 12 P11802,O14920,P06400,O00459,Q00534,P31751,P06756 7 +P53 signaling pathway 0.3781057282614251 0.2442289897610083 0.8070534761587616 1.0 1.0 11 P49327,P11802,P31350,P06493 4 +Histidine metabolism 0.3700421686891941 0.233155723477659 0.8156404859270374 1.0 1.0 6 P51648 1 +Chronic myeloid leukemia 0.3611868367472881 0.215634702548427 0.8292725033831561 1.0 1.0 18 P06400,P11802,P46108,P46109 4 +Gap junction 0.3617012693900441 0.1910251774582713 0.8485058676055841 1.0 1.0 14 P04899,P63096,Q07157,Q9BUF5,Q13509,P07437,P04350,P06493 8 +Non small cell lung cancer 0.3619280414555957 0.1888135625255958 0.8502389416826222 1.0 1.0 12 P11802,P06400,P42771,O00459,Q00534,Q13043 6 +Steroid hormone biosynthesis 0.523433319200665 0.1862837906138679 0.8522222181969585 1.0 1.0 3 Q53GQ0 1 +Progesterone mediated oocyte maturation 0.3342341361633085 0.1734230996440144 0.8623188693049888 1.0 1.0 23 P53350,P63096,P08238,P07900,O00459,P30260,P14635,Q16539,Q9UJX4,Q13042,P06493 11 +Ecm receptor interaction 0.3447303038315819 0.1168558598275724 0.9069742771836518 1.0 1.0 5 Q7L0J3,Q08722 2 +Natural killer cell mediated cytotoxicity 0.3367441423096493 0.1085414999355539 0.9135661627614762 1.0 1.0 14 P49327,P04439,P10321,P01889 4 +Toll like receptor signaling pathway 0.3319833916230673 0.1005173062048211 0.9199336440550934 1.0 1.0 11 Q16539,O00459,P42224 3 +Chemokine signaling pathway 0.3171149595647587 0.0979640151410316 0.921960867639146 1.0 1.0 23 P04899,P63096,O14920,O00459,P40763,P46108,P49841,P42224,Q13153,P31751,P46109,P41240 12 +Leishmania infection 0.3180398340163148 0.0890226667394587 0.9290638961835702 1.0 1.0 7 Q16539,P42224 2 +Thyroid cancer 0.3153514180024769 0.0761826777964331 0.9392737637512728 1.0 1.0 8 P06753,P28482,Q92734,P04637,P35222,Q16204,Q13772 7 +Pentose and glucuronate interconversions 0.3272783251231413 0.0725505973936018 0.9421637406257236 1.0 1.0 4 P15121,Q16851,Q7Z4W1 3 +Tyrosine metabolism 0.3071569201586471 0.0590056573248782 0.95294760207157 1.0 1.0 8 Q7Z4G4,P14174,P21964 3 +Lysine degradation 0.2822970518988809 0.0422696922527681 0.9662837057620284 1.0 1.0 28 Q8WTS6,P40939,P51648,P35610,Q9NVH6 5 +Jak stat signaling pathway 0.2936773596387153 0.0412187456341041 0.9671215095167098 1.0 1.0 7 P40763,O00459,P42224 3 +Prion diseases 0.4655384615384651 0.0387175429849012 0.9691155866165456 1.0 1.0 2 P31948 1 +Primary bile acid biosynthesis 0.4375384615384614 0.0339306942748662 0.9729324167824572 1.0 1.0 2 P51659 1 +Viral myocarditis 0.2967129228448317 0.0193646325581308 0.984550224244926 1.0 1.0 11 P10321,P01889 2 +Fatty acid metabolism 0.2737776106645513 0.0039787613508257 0.9968254161229564 1.0 1.0 28 Q9UKU0,P23786,P40939 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5c6914697a64dadf41bcffa8fa2f54b190eb2d00 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAR", "ADH5", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APIP", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AURKA", "B3GAT3", "B4GAT1", "BAIAP2", "BCAS2", "BCKDHA", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BRD8", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CAMKK2", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CBR1", "CCDC6", "CCNB1", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "COMT", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPOX", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CXADR", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DARS", "DARS2", "DBI", "DBT", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GFPT1", "GGA3", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPA1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "KEAP1", "KIDINS220", "L2HGDH", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LDHA", "LDHB", "LIG1", "LIG3", "LIPA", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LYPLA1", "M6PR", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGAT1", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MSH2", "MSH3", "MSH6", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCOA4", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NF1", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NNT", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NTHL1", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC3", "OXA1L", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PAOX", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS1", "PDSS2", "PECR", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PI4KA", "PIGA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTDSS1", "PTGES2", "PTPN1", "PTPN11", "PUF60", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QPRT", "RAB11B", "RAB13", "RAB23", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RCOR1", "RDH11", "RDX", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RIPK1", "RNASEH2A", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC33A1", "SLIT2", "SLK", "SLTM", "SMAP2", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SPCS2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK3", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "TAB1", "TAF6L", "TALDO1", "TAOK1", "TAP1", "TARS", "TARS2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TK1", "TKFC", "TKT", "TLN1", "TMLHE", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIM32", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TTC37", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UGDH", "UGP2", "ULK3", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USP39", "USP8", "UXS1", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS37B", "VPS45", "VPS4A", "WARS", "WARS2", "WASF2", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX3", 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0.2864106402914596 0.1192008340234222 1.0 0.2685353106225043 0.0424141111811751 0.2048311214647369 +Diseases of carbohydrate metabolism 3 9 2.02475834928082 0.0428921838414542 3.5024271844660193 9.050970873786408 0.3053509571481614 0.2820635836848948 1.390848707873377 1.194576753712748 1.470873952821233 0.2708232247081553 0.0007837622690909 0.1049896535105009 0.0206800818926893 0.0021324559374895 0.0239311550263785 +Degradation of axin 15 36 2.019364303370354 0.043449368887146 11.135922330097088 36.5 0.6371703324335989 0.5044883973483546 6.515923056292238 1.1005294401076644 1.2875505119575097 0.3689236351245595 0.0120022024615916 0.2068720246529641 0.0111977735740575 0.0060702567763488 0.0020807979317993 +Cross presentation of soluble exogenous antigens endosomes 15 36 2.019364303370354 0.043449368887146 11.097087378640778 36.91019417475728 0.6471378136535638 0.507052502601231 6.457500437861876 1.2421375880066114 1.2717860238430438 0.3672755762882163 0.0069073239944113 0.1795501084992132 0.0072464589525271 0.0030498705228987 0.0007113894889706 +Mitochondrial protein import 6 33 2.0153530333875715 0.0438676718163428 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 0.0047281830929855 0.0028071579475431 0.0025290933815156 0.0005499789048842 0.0021158970815754 +Regulation of ras by gaps 16 38 1.979730109603432 0.0477338633679944 11.558252427184469 38.29611650485437 0.5949031665539309 0.5179046122727133 6.637200606991292 1.5039380235434 1.2829290056167597 0.3733028763215757 0.0214251144559834 0.2406936845278361 0.0177960185678587 0.0124412460735711 0.0062070298083063 +The role of gtse1 in g2 m progression after g2 checkpoint 23 47 1.9793101506704047 0.0477810974460122 14.79611650485437 48.84466019417476 0.6226477470486884 0.5168095546238419 7.820323564061835 1.8499922936255029 1.3076695437390702 0.3722860732713196 0.0360715155291877 0.2766173679843171 0.0271898890726632 0.0236138009368106 0.0050990578248913 +Degradation of dvl 15 37 1.963732465508496 0.0495611255518004 11.50728155339806 37.79611650485437 0.5954952616194853 0.5106657090472662 6.536116642578212 1.2295647923796569 1.2774118860610646 0.3695881914917919 0.0138043868233178 0.2145132052152406 0.0125141686162342 0.0072215435094453 0.0027178195947894 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..abfe86951fd3350e48da501bf9f2123d0075ad8a --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 1388, + "title": "Average number of proteins per term", + "value": 19.738472622478387 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c9e437015cb9edb8f278ff31c1b3fb26403c7a3d --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..35e9f3661eccd8dd57e3bc087191e1d888af1ce9 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,401 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolism 0.7703827613892084 2.8432456362408183 0.0044656638923052 0.9979952234656976 1.0 24 P06280,P16278,Q13510,P06865,P17900,P10619,P04062,Q06136,P07602,O95470 10 +Response to elevated platelet cytosolic ca2 0.5839887858698332 2.596188082510263 0.0094264449729344 0.9999980466472 1.0 34 Q8NBM8,Q9NTK5,P05067,Q08380,Q15833,O43852,P07602,Q8NBX0,P13473 9 +Glycosphingolipid metabolism 0.8458863568249706 2.508986718278728 0.0121078036814359 0.9999999546202522 1.0 14 P06280,P16278,Q13510,P17900,P10619,P04062,P07602 7 +Metabolism of porphyrins 0.8481549268355971 2.286681596426848 0.0222144146583878 0.9999999999999712 1.0 8 P30519,P33527,P09601 3 +Metabolism of polyamines 0.5513619739522548 2.28054325202185 0.022575488598076 0.9999999999999828 1.0 38 P62333,O75832,P28070,P28074,P25787,O00231,Q9UL46,Q92530,Q6QHF9,P19623,P28072,P61289,P60900,P49721,P20618,Q99436 16 +Heme degradation 0.9344408060197088 2.2710080226010496 0.0231464922939834 0.9999999999999925 1.0 4 P30519,P09601 2 +Keratan sulfate degradation 0.884758922787638 2.2218452299772578 0.026293766860173 1.0 1.0 5 P15586,P16278 2 +Class a 1 rhodopsin like receptors 0.8291487065317015 2.180085118268934 0.029251152675811 1.0 1.0 7 P42892,P05067,P07602,P04083 4 +Peptide ligand binding receptors 0.8291487065317015 2.180085118268934 0.029251152675811 1.0 1.0 7 P42892,P05067,P07602,P04083 4 +Hedgehog ligand biogenesis 0.5378301164897866 2.142071795330041 0.0321877051203274 1.0 1.0 40 Q13438,P62333,O75832,P07237,P28070,P25787,P28074,O00231,Q9UL46,Q9UBV2,P49720,Q92530,P28072,P61289,P60900,P49721,P20618,Q99436 18 +Mucopolysaccharidoses 0.9001340265663847 2.133979944060429 0.0328444225924313 1.0 1.0 4 P54802,P15586 2 +Gpcr ligand binding 0.8018945591399649 2.117919106769252 0.0341819191495356 1.0 1.0 9 P42892,P05067,P07602,P04083 4 +Keratan sulfate keratin metabolism 0.8050072789426721 2.056184338873416 0.0397647512608767 1.0 1.0 6 P15586,P16278,P06865 3 +Cdt1 association with the cdc6 orc origin complex 0.5218542897716968 2.0489060988588848 0.0404712978594608 1.0 1.0 38 P62333,O75832,Q9Y619,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 16 +Chondroitin sulfate dermatan sulfate metabolism 0.8423227350111793 2.048828714781521 0.0404788668587423 1.0 1.0 5 Q8N6G5,P06865 2 +Ras processing 0.8757782391858138 2.035575840138137 0.0417929658622526 1.0 1.0 4 O60725 1 +Diseases of carbohydrate metabolism 0.7806049957222174 2.0247583492808197 0.0428921838414542 1.0 1.0 9 P54802,P15586,P10253 3 +Degradation of axin 0.5139626556789034 2.019364303370354 0.043449368887146 1.0 1.0 36 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Cross presentation of soluble exogenous antigens endosomes 0.5139626556789034 2.019364303370354 0.043449368887146 1.0 1.0 36 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Mitochondrial protein import 0.5071504021896759 2.0153530333875715 0.0438676718163428 1.0 1.0 33 Q13505,P21796,Q9NS69,Q99595,Q8N4H5,Q9Y584 6 +Regulation of ras by gaps 0.5131706351559333 1.979730109603432 0.0477338633679944 1.0 1.0 38 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P21359,P61289,P60900,P49721,P20618,Q99436 16 +The role of gtse1 in g2 m progression after g2 checkpoint 0.5315478403467465 1.9793101506704052 0.0477810974460122 1.0 1.0 47 P53350,P28070,P49720,P04350,P14635,P49721,Q99436,P25787,P28074,O00231,P61289,Q9UL46,P08238,P07900,Q13509,P28072,P60900,Q92530,P06493,P62333,O75832,Q15691,P20618 23 +Degradation of dvl 0.5090943246503812 1.9637324655084956 0.0495611255518004 1.0 1.0 37 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Trans golgi network vesicle budding 0.5059724417331516 1.9553872853944585 0.0505373757015139 1.0 1.0 36 P15586,P11717,Q10567,Q9Y5X3,O43493,P05067,Q92572,Q92538,P50570,P09496,P20645,P02792,Q9BXS5,P61966 14 +Transport of inorganic cations anions and amino acids oligopeptides 0.7553699139908893 1.9411228287393791 0.0522433806676951 1.0 1.0 10 Q9UBX3,P30626,Q70HW3 3 +Endosomal vacuolar pathway 0.8522167487684703 1.9395286828289129 0.0524369954086632 1.0 1.0 4 Q9UIQ6,P01889,P10321 3 +Nef mediated downregulation of mhc class i complex cell surface expression 0.8142916513413361 1.932852016755788 0.0532544303105075 1.0 1.0 5 Q10567,P04439,P61966 3 +Lysosome vesicle biogenesis 0.7219094865209107 1.9245292221633956 0.0542882814825123 1.0 1.0 14 P15586,Q10567,P05067,P50570,P09496,P20645,Q9BXS5,P61966 8 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7267208472338258 1.9084982045910015 0.0563268549992286 1.0 1.0 13 P05067,O43681,Q7L5D6,P51648,P46379,P09601,Q13190 7 +Pink1 prkn mediated mitophagy 0.7536722248491005 1.880639424610132 0.0600209849404822 1.0 1.0 8 Q9NS69,P21796 2 +Abc transporter disorders 0.5076195866734082 1.8694063735870856 0.06156629852108 1.0 1.0 42 Q13438,P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q9UBV2,P49720,Q92530,P28072,P61289,P60900,P49721,P20618,Q99436 17 +Defective cftr causes cystic fibrosis 0.5076195866734083 1.8694063735870856 0.06156629852108 1.0 1.0 42 Q13438,P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q9UBV2,P49720,Q92530,P28072,P61289,P60900,P49721,P20618,Q99436 17 +Auf1 hnrnp d0 binds and destabilizes mrna 0.5032950834692027 1.8674343180378048 0.0618409611279859 1.0 1.0 40 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P11940,P28072,P61289,P60900,P49721,P20618,Q99436 16 +Slc mediated transmembrane transport 0.6162122815898952 1.860054466201043 0.0628778204308446 1.0 1.0 23 Q70HW3,O00400,P30626,Q9UBX3,Q8TAD4,Q15043,Q8TB61 7 +Cellular response to hypoxia 0.500193454577664 1.858939320269721 0.0630357398633569 1.0 1.0 39 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Hedgehog on state 0.504562240128333 1.844825221081276 0.0650629673317313 1.0 1.0 42 P62333,O75832,Q9Y496,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P20618,P28072,Q96J02,P61289,P60900,P49721,Q6PHR2,Q99436 18 +Glycosaminoglycan metabolism 0.6878586722473873 1.8417259437647189 0.0655152473105333 1.0 1.0 16 P54802,P15586,P16278,P06865,Q8NCH0,Q8N6G5 6 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.7482470524711388 1.8349957765155651 0.0665063152474341 1.0 1.0 7 P30153,P06400,P30154,Q14181 4 +Purinergic signaling in leishmaniasis infection 0.8261753545809949 1.83244904642248 0.0668845465210534 1.0 1.0 4 P09601 1 +Aquaporin mediated transport 0.8256132424207274 1.8301275205264311 0.0672308725977877 1.0 1.0 4 Q99797 1 +G1 s specific transcription 0.7352152103064039 1.823054749282238 0.0682950991631381 1.0 1.0 9 P00374,P04818,Q9Y619,P31350,P06493 5 +Regulation of runx3 expression and activity 0.4934964308579077 1.8213551635890135 0.0685528860607802 1.0 1.0 38 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Asymmetric localization of pcp proteins 0.4893380418170754 1.8042533332754855 0.071191601915022 1.0 1.0 37 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Inflammasomes 0.7777205972671308 1.7796319105933236 0.0751362203095697 1.0 1.0 5 P09601 1 +The nlrp3 inflammasome 0.7777205972671308 1.7796319105933236 0.0751362203095697 1.0 1.0 5 P09601 1 +Diseases associated with glycosaminoglycan metabolism 0.7669818500097191 1.7342554545340876 0.0828727674655884 1.0 1.0 5 Q8NCH0,Q93063,P06865 3 +Dap12 interactions 0.7249377327198354 1.7155232193523575 0.0862493420530154 1.0 1.0 6 P10321 1 +Regulation of pten stability and activity 0.4852045094681795 1.7043895819423671 0.0883083289442434 1.0 1.0 41 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Glycogen breakdown glycogenolysis 0.7176546605438869 1.701307037933547 0.0888853470978545 1.0 1.0 7 P10253,P46020 2 +Mastl facilitates mitotic progression 0.758238373883592 1.6971893999888694 0.0896608585031 1.0 1.0 5 O43768,P14635,P30154,P06493 4 +Degradation of gli1 by the proteasome 0.4795681781642618 1.6913223359499467 0.0907752563395867 1.0 1.0 39 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,Q96J02,P61289,P63208,P60900,P49721,P20618,Q99436 17 +Signaling by notch4 0.4846351670449996 1.667058455005232 0.0955027820254719 1.0 1.0 43 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P20618,P28072,Q04721,P61289,P63208,Q92542,P49721,P60900,Q99436 18 +Sphingolipid de novo biosynthesis 0.6902564930129088 1.643138406737621 0.1003543000525932 1.0 1.0 10 Q06136,Q96G23,P51648,O95470 4 +Heparan sulfate heparin hs gag metabolism 0.7440714505697386 1.6369139332976483 0.1016484541909341 1.0 1.0 5 P54802,O94766,Q93063,P16278 4 +Scf skp2 mediated degradation of p27 p21 0.4755603383203136 1.6255334790985134 0.1040489362143903 1.0 1.0 41 P62333,O75832,P11802,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P63208,P60900,P49721,P20618,Q99436 17 +Cyclin a cdk2 associated events at s phase entry 0.4787872346278953 1.6192913036146164 0.1053846009141201 1.0 1.0 43 P62333,O75832,P11802,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P06400,P28072,P61289,P63208,P60900,P49721,P20618,Q99436 18 +Fceri mediated nf kb activation 0.4824931753439417 1.6171734119643342 0.1058408538484174 1.0 1.0 45 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P49427,P61289,Q9UDY8,P61088,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P20618 20 +Sialic acid metabolism 0.77222382607006 1.607882858926834 0.1078608366355537 1.0 1.0 4 P10619 1 +Stabilization of p53 0.4712533539465501 1.6066050388997462 0.1081410364580901 1.0 1.0 40 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Signaling by hedgehog 0.5041154158476957 1.603499856660612 0.1088243407516529 1.0 1.0 57 Q13438,P28070,Q9UBV2,P49720,P04350,P63208,P49721,Q6PHR2,Q99436,P07237,P25787,P28074,O00231,Q9Y496,Q96J02,P61289,Q9UL46,Q13509,P28072,P60900,Q92530,P62333,O75832,Q9Y366,P10644,P20618 26 +Cargo recognition for clathrin mediated endocytosis 0.4557281215579868 1.5952691686367833 0.1106520570189999 1.0 1.0 33 P11717,O14657,O43493,P09496,Q14108,Q9UBW8,P20645,Q9Y6I3,P51809,Q9BT78,Q9NVZ3 11 +Negative regulation of notch4 signaling 0.4694660093441232 1.5919006467195802 0.1114070302350025 1.0 1.0 40 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P63208,P60900,P49721,P20618,Q99436 16 +Inositol phosphate metabolism 0.6920902211390092 1.5883885071606605 0.1121985146881721 1.0 1.0 7 P29218,Q9BW91 2 +E2f mediated regulation of dna replication 0.6726996068846903 1.5869102815983611 0.1125329659582687 1.0 1.0 11 P06400,P30154,P14635,P30153,Q14181,Q9Y619,P06493 7 +Regulation of signaling by cbl 0.7664011252633259 1.5834598577896246 0.1133166891535792 1.0 1.0 4 P46108,P46109 2 +Transcriptional regulation by runx3 0.4721676117845975 1.5813189066259754 0.1138051387737084 1.0 1.0 42 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +G1 s dna damage checkpoints 0.4683700607393029 1.566447076135618 0.117243989335493 1.0 1.0 41 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P60900,P49721,P20618,Q99436 15 +Hedgehog off state 0.4855379177976588 1.5621654849916904 0.1182490092794674 1.0 1.0 50 P28070,P49720,P04350,P63208,P49721,Q99436,Q9Y496,P25787,P28074,O00231,Q96J02,P61289,Q9UL46,Q13509,P28072,P60900,Q92530,P62333,O75832,Q9Y366,P10644,P20618 22 +Regulation of runx2 expression and activity 0.4696084740604446 1.5602809913699325 0.1186934933815431 1.0 1.0 42 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P42224,P61289,P63208,P60900,P49721,P20618,Q99436 17 +Heme signaling 0.7251578644385055 1.55605620223135 0.1196947285164804 1.0 1.0 5 P09601 1 +Unfolded protein response upr 0.4646916017391675 1.5525485554926748 0.1205310240649728 1.0 1.0 40 P43307,Q92945,Q8N6T3,O43731,Q9UBS4,O95070,O14773,Q9NWM8,Q9Y5M8 9 +Mitophagy 0.6575538864616319 1.542324866385992 0.1229946692177781 1.0 1.0 12 Q9NS69,P21796 2 +Interleukin 1 signaling 0.4730599132176568 1.539975009668006 0.1235664450610671 1.0 1.0 45 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P61289,P61088,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P05067,P20618 19 +Signaling by notch3 0.6782310677425392 1.511815239413945 0.1305808714519569 1.0 1.0 6 P67809,Q92542 2 +Orc1 removal from chromatin 0.4748217172402399 1.5063751398056433 0.1319708988362622 1.0 1.0 48 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,P33993,P55036,P61289,Q9Y619,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P20618 19 +Binding and uptake of ligands by scavenger receptors 0.6695455521914804 1.4880054551590232 0.1367494549978816 1.0 1.0 7 Q8WTV0 1 +Dectin 1 mediated noncanonical nf kb signaling 0.458074231246566 1.4814351625678217 0.1384906505598326 1.0 1.0 41 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P63208,P60900,P49721,P20618,Q99436 16 +Tnfr2 non canonical nf kb pathway 0.4580742312465659 1.4814351625678193 0.1384906505598333 1.0 1.0 41 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P61289,P63208,P60900,P49721,P20618,Q99436 16 +Formyl peptide receptors bind formyl peptides and many other ligands 0.9173884330850396 1.475040344667782 0.1402016971048549 1.0 1.0 3 P05067 1 +Iron uptake and transport 0.5910332636671817 1.4666098991675165 0.1424822055955721 1.0 1.0 19 P30519,Q9Y487,Q15904,P09601,P02792 5 +Dna replication initiation 0.6670328379699996 1.4625266092488591 0.1435969580577651 1.0 1.0 6 P56282,Q14181 2 +Mapk6 mapk4 signaling 0.4665628885772517 1.4545276085360228 0.1458000848312866 1.0 1.0 47 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,Q9HCE1,P28072,P61289,P60900,P49721,P20618,Q99436,P06493 17 +Rhoa gtpase cycle 0.4700759614062497 1.4516052560903077 0.146611396447633 1.0 1.0 49 O15173,Q8TAA9,O15498,Q8NBN3,O75955,P30519,Q15904,Q14739,P41440,Q86VI3,Q13190,P27105 12 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4500680032751712 1.4478458771169938 0.14766015901716 1.0 1.0 39 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,Q96J02,P61289,P60900,P49721,P20618,Q99436 16 +Metabolism of nitric oxide nos3 activation and regulation 0.6965652953521229 1.4331098246906926 0.151826454182185 1.0 1.0 5 P50570,P35270 2 +Regulation of hmox1 expression and activity 0.4596470615691347 1.4295642055304283 0.1528421350296986 1.0 1.0 45 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P28072,P09601,P61289,P63208,P60900,P49721,P20618,Q99436 17 +Downstream signaling events of b cell receptor bcr 0.4539930007328523 1.415067185551408 0.1570487982365698 1.0 1.0 43 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P20618,P28072,P61289,P63208,P60900,P49721,Q9UDY8,Q99436 17 +Cyclin a b1 b2 associated events during g2 m transition 0.6391532128288008 1.4041607962907108 0.1602709730055234 1.0 1.0 10 P53350,P63151,P30154,P14635,Q9Y570,P06493 6 +Ire1alpha activates chaperones 0.5307139589732196 1.3993818359110717 0.1616985108644586 1.0 1.0 24 P43307,Q8N6T3,O43731,Q9UBS4,O95070,O14773,Q9NWM8 7 +Transcriptional regulation by runx2 0.4667418748842374 1.3927497639321187 0.1636954744082164 1.0 1.0 51 P11802,P28070,P49720,P14635,P63208,P49721,Q99436,P25787,P28074,O00231,P61289,Q9UL46,P06400,P28072,P60900,Q92530,P06493,P62333,O75832,P42224,P20618 21 +Metabolism of folate and pterines 0.6396432501750545 1.3688419346986331 0.1710486894436829 1.0 1.0 8 Q9H2D1,P41440 2 +Interleukin 1 family signaling 0.456137822677466 1.3685977489031966 0.1711250480722876 1.0 1.0 47 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P61289,P61088,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P05067,P20618 19 +Synaptic adhesion like molecules 0.7130534100169964 1.3585683974433311 0.1742833950744855 1.0 1.0 4 O75955,P41440 2 +Regulation of innate immune responses to cytosolic dna 0.7121352944645795 1.3546864765065487 0.1755174683344464 1.0 1.0 4 P19474 1 +Notch3 activation and transmission of signal to the nucleus 0.8846626579367634 1.350077065518584 0.176991264112114 1.0 1.0 3 P67809 1 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6033120087881981 1.3331296612461496 0.1824892570719094 1.0 1.0 14 P42575,P61088,P08238,P05067,Q15750,Q9Y2Z0,Q96J02,P09601,Q16539 9 +Signaling by the b cell receptor bcr 0.4433726177580568 1.2947524940902126 0.195405624765214 1.0 1.0 45 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P20618,P28072,P61289,P63208,P60900,P49721,Q9UDY8,Q99436 17 +Clec7a dectin 1 signaling 0.4504155996895168 1.2896835260179762 0.1971605617190923 1.0 1.0 49 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P49427,P61289,Q9UDY8,P61088,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P20618 20 +Regulation of mrna stability by proteins that bind au rich elements 0.4690480401609747 1.2884938173733254 0.197574119650312 1.0 1.0 59 Q01105,Q92945,P28070,Q9UL46,Q92530,P20618,P28072,Q92973,Q16539,P49721,P60900,Q9NQT5 12 +Constitutive signaling by egfrviii 0.6960886147866405 1.286823843249283 0.1981556943958513 1.0 1.0 4 Q16543 1 +Signaling by egfr in cancer 0.6960886147866405 1.286823843249283 0.1981556943958513 1.0 1.0 4 Q16543 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.6960886147866405 1.286823843249283 0.1981556943958513 1.0 1.0 4 Q16543 1 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4529513280520331 1.279294760909659 0.2007932768341884 1.0 1.0 51 P53350,O75832,Q13042,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P06400,P30260,P28072,Q9UJX4,P61289,P60900,P49721,P20618,Q99436 18 +Antigen processing cross presentation 0.4522035526320824 1.2731293879956207 0.2029721321127793 1.0 1.0 51 O75832,P04439,P28070,P28074,P25787,Q03518,O00231,Q9UL46,Q92530,P10321,P01889,P28072,P60900,Q9UIQ6,P49721,P20618,Q99436 17 +Visual phototransduction 0.6211577400197789 1.2593125628312418 0.2079174573374698 1.0 1.0 6 P53582,Q6NUM9 2 +Ripk1 mediated regulated necrosis 0.6037775450486572 1.257121729981772 0.2087095596906623 1.0 1.0 11 P49327,Q16543,P07900,O75955,O00560,P41440 6 +Diseases associated with glycosylation precursor biosynthesis 0.615775914209394 1.2463305340615671 0.2126430724238055 1.0 1.0 7 P10619 1 +Activation of nima kinases nek9 nek6 nek7 0.6859605911329995 1.243998651124817 0.2135000593715437 1.0 1.0 4 P53350,P14635,P06493 3 +Carboxyterminal post translational modifications of tubulin 0.6527440685411087 1.2436224395495508 0.2136385535095053 1.0 1.0 5 P04350,Q13509 2 +Mrna decay by 3 to 5 exoribonuclease 0.5793578146590194 1.2414679816350231 0.2144329191625753 1.0 1.0 15 Q9NQT5,Q969T7,Q6PGP7,Q15477 4 +Leishmania infection 0.4214293945985149 1.2410503134538755 0.2145871628608344 1.0 1.0 37 P05067,P46108,Q9UQB8,P09601,Q16539 5 +Interleukin 3 interleukin 5 and gm csf signaling 0.6157878344293305 1.2354329876521242 0.2166694020970836 1.0 1.0 6 P46108,P46109 2 +Phosphorylation of emi1 0.6828817733990092 1.2309851316701368 0.2183284252424664 1.0 1.0 4 P53350,P14635,P06493 3 +Rho gtpases activate iqgaps 0.5978498557221936 1.2285483662728025 0.219241184741626 1.0 1.0 11 Q86VI3,Q13509 2 +Gap junction assembly 0.6820227361151002 1.2273547331785528 0.2196892922280757 1.0 1.0 4 P04350,Q13509 2 +Transport of connexons to the plasma membrane 0.6820227361151002 1.2273547331785528 0.2196892922280757 1.0 1.0 4 P04350,Q13509 2 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5470032611306243 1.217641192874808 0.2233603534308552 1.0 1.0 19 P07237,P05067,Q06481,O43852,Q02818,Q9BTY2 6 +Cargo trafficking to the periciliary membrane 0.5367185226122655 1.2045224878880725 0.2283876956337653 1.0 1.0 20 Q9UPT5,Q10713,Q92538,Q9H0F7,A6NIH7 5 +Complex i biogenesis 0.4202170823157095 1.202662531229509 0.2291069389517095 1.0 1.0 31 O75380,O43676,Q8N183,Q9P0J0,O95168,Q9BU61,O95182,Q9Y6M9,O75306 9 +Metabolism of fat soluble vitamins 0.845632696030865 1.201442589743926 0.229579563671721 1.0 1.0 3 Q8N0U8 1 +Negative regulation of mapk pathway 0.5866966141504228 1.196320046820744 0.2315716886519434 1.0 1.0 12 Q6UWU4,P30086,P30154,Q7Z569 4 +Inactivation of cdc42 and rac1 0.674191538240211 1.1942735396720303 0.2323709846191941 1.0 1.0 4 Q9Y6N7 1 +Collagen biosynthesis and modifying enzymes 0.5893007794309011 1.1873164269553054 0.2351028309517993 1.0 1.0 11 O75718,O15460,Q32P28 3 +Pyrimidine salvage 0.8412823120759716 1.184937019977876 0.2360423489799417 1.0 1.0 3 Q08623 1 +Tcr signaling 0.4408277694794807 1.1792152620003884 0.2383124703218824 1.0 1.0 51 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,P49427,P61289,Q9UDY8,P61088,Q9UL46,O00459,P28072,P60900,Q92530,P62333,O75832,P20618 20 +Degradation of beta catenin by the destruction complex 0.4360490558647604 1.1552072113679674 0.2480055823332327 1.0 1.0 50 P62333,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P49720,P30154,P28072,P30153,P61289,P63208,P60900,P49721,P20618,Q99436 18 +Abc family proteins mediated transport 0.4433342414975501 1.1537157647937777 0.2486167185026797 1.0 1.0 54 Q13438,P28070,Q9UBV2,P49720,P33527,P49721,Q99436,P08183,P56589,P25787,P28074,O00231,Q9NUT2,P61289,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P20618 21 +Retrograde transport at the trans golgi network 0.4817992382076227 1.14756918670731 0.2511464562042966 1.0 1.0 25 P11717,O60499,O43493,Q8N2H4,P20645,Q9UIL1,Q7Z6M1 7 +Switching of origins to a post replicative state 0.4478235068775035 1.1450306107058936 0.2521964773442313 1.0 1.0 57 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,P33993,P30260,P55036,P61289,Q9Y619,Q9UJX4,Q13042,Q9UL46,P33992,P28072,P60900,Q92530,P62333,O75832,P20618 23 +Metabolism of cofactors 0.5936207349746045 1.136796230677595 0.2556234794547336 1.0 1.0 6 O75874,P35270 2 +Copi dependent golgi to er retrograde traffic 0.4352112307285692 1.1173877684973177 0.2638285626839072 1.0 1.0 52 Q9H0H5,Q9P2W9,Q9H0U4,O15260,Q8N6T3,P24390,Q9NSK0,Q92538,Q13509,O43731,P04350,Q9Y3B3,P52732 13 +Fc epsilon receptor fceri signaling 0.4381169414254427 1.1107526967013504 0.2666748126789255 1.0 1.0 54 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P49427,P61289,Q9UDY8,P61088,Q9UL46,O00459,P28072,P60900,Q92530,P62333,O75832,P20618 21 +Metabolism of steroid hormones 0.6219632993028243 1.1104286836259591 0.2668143436622048 1.0 1.0 5 P30536 1 +Synthesis of ip2 ip and ins in the cytosol 0.649564433171606 1.0905158072992156 0.2754859940291796 1.0 1.0 4 P29218 1 +Pcp ce pathway 0.4190568137097994 1.060921999426754 0.2887253505491252 1.0 1.0 47 P62333,O75832,P07737,P28070,P25787,P28074,O00231,Q9UL46,Q92530,P28072,P09496,P61289,P60900,P49721,P20618,Q99436 16 +Nr1h2 and nr1h3 mediated signaling 0.6078113802128083 1.0493766110650729 0.2940048185215009 1.0 1.0 5 Q9HCE1,P49327,Q8NB78 3 +Cytochrome p450 arranged by substrate type 0.8048979210616889 1.0477259142444035 0.2947649045153961 1.0 1.0 3 Q16850 1 +Josephin domain dubs 0.8033973760175799 1.0421072453484184 0.297361959808011 1.0 1.0 3 P54725 1 +Oncogene induced senescence 0.5624869288416388 1.0058372005310958 0.3144938891795323 1.0 1.0 7 Q9HCE1,P06400 2 +C type lectin receptors clrs 0.4210898586386867 1.0008260923608896 0.316910892656467 1.0 1.0 52 P28070,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,Q15750,P49427,P61289,Q9UDY8,P61088,Q9UL46,P28072,P60900,Q92530,P62333,O75832,P20618 20 +Mitotic g1 phase and g1 s transition 0.4617317157918738 0.9968442588977344 0.3188401114950472 1.0 1.0 75 P11802,P28070,P00374,P49720,P14635,Q14181,P30153,P63208,P49721,Q99436,P25787,P28074,P49642,O00231,P30154,P33993,P55036,P61289,Q9Y619,Q9UL46,P56282,P06400,P28072,P60900,Q92530,P31350,P06493,P62333,O75832,P63151,P04818,P12004,P20618 33 +Interleukin 12 signaling 0.4493145922086903 0.9953261175786124 0.3195776791685709 1.0 1.0 26 P07237,O14979,Q9UL46,Q00169,P11233,P51809,P52597,P14174,Q13126 9 +Hs gag degradation 0.949230769230767 0.9936520581217024 0.3203922905292384 1.0 1.0 2 P54802 1 +Synthesis of leukotrienes lt and eoxins ex 0.7876692819147331 0.9834604011876928 0.3253808953578434 1.0 1.0 3 P09960 1 +Noncanonical activation of notch3 0.9443076923076924 0.9769322670239232 0.3286026860498812 1.0 1.0 2 P67809 1 +Beta catenin independent wnt signaling 0.415880912853901 0.9730457711570848 0.3305305541264176 1.0 1.0 51 O75832,P07737,P28070,P25787,P28074,O00231,Q9UL46,Q92530,Q9HCE1,P28072,P09496,P61289,P60900,P49721,P20618,Q99436 16 +Interleukin 12 family signaling 0.4149204965453454 0.9727685072193738 0.3306683680496205 1.0 1.0 29 P07237,O14979,Q9UL46,Q00169,P42224,P11233,P51809,P52597,P14174,Q13126 10 +The phototransduction cascade 0.6211502027317779 0.9717323463250258 0.3311837204364338 1.0 1.0 4 P53582 1 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.58930987568665 0.9699205458946866 0.3320860979735136 1.0 1.0 5 P10321,P01889 2 +Amino acid transport across the plasma membrane 0.6197660098522101 0.965982806566268 0.3340527845129171 1.0 1.0 4 P08195,Q15758,P30825 3 +Interleukin 2 family signaling 0.619694748457412 0.9656869178895252 0.3342008675900212 1.0 1.0 4 O00459,P42224 2 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.619694748457412 0.9656869178895252 0.3342008675900212 1.0 1.0 4 O00459,P42224 2 +Beta oxidation of butanoyl coa to acetyl coa 0.7824835045792841 0.9642320881883586 0.3349295801414316 1.0 1.0 3 P40939 1 +Biological oxidations 0.3979502979432088 0.9632542257505512 0.3354199584795183 1.0 1.0 42 O15217,Q9NUJ1,Q6QHF9,O43169,Q8TB61 5 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7811634349030488 0.959346811959218 0.3373840601507178 1.0 1.0 3 P35270,P00374 2 +Mitochondrial calcium ion transport 0.5197154458771361 0.958777588435494 0.3376708018154168 1.0 1.0 16 Q10713,P45880,P21796 3 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6173029556650178 0.9557622383739136 0.3391923703025035 1.0 1.0 4 Q00534,P06400,P11802 3 +Cytoprotection by hmox1 0.4326893456883632 0.9472579331052404 0.3435073610403121 1.0 1.0 62 P00403,P30519,P28072,P33527,P09601,P60900,P49721,P20618 8 +Transport of bile salts and organic acids metal ions and amine compounds 0.6117174238418546 0.9326360532561452 0.35100791186558 1.0 1.0 4 Q8TAD4 1 +Telomere c strand synthesis initiation 0.5472054519099586 0.9309715439891252 0.351868284074798 1.0 1.0 6 Q14181,P49642 2 +Synthesis of pa 0.541391889488979 0.9292881600076676 0.352739769535533 1.0 1.0 9 Q9HCL2 1 +Dna replication pre initiation 0.4230950639006264 0.927593166529231 0.3536186437357469 1.0 1.0 58 P28070,P49720,Q14181,P49721,Q99436,P25787,P28074,P49642,O00231,P33993,P55036,P61289,Q9Y619,Q9UL46,P56282,P28072,P60900,Q92530,P62333,O75832,P20618 21 +Uch proteinases 0.3978321843423789 0.9155350154635348 0.3599108289144022 1.0 1.0 45 P62333,O75832,P28070,P28074,P25787,O00231,Q9UL46,Q92530,P28072,Q8NB78,P61289,P60900,P49721,P20618,Q99436 15 +Small interfering rna sirna biogenesis 0.6056201691829562 0.9074788039962192 0.364153653279843 1.0 1.0 4 Q15631 1 +Platelet sensitization by ldl 0.5393445223232894 0.9020978323242996 0.367004900284972 1.0 1.0 7 P30154 1 +Cdc42 gtpase cycle 0.3772646918904265 0.9007448950915924 0.3677239723854197 1.0 1.0 35 Q8TAA9,O15498,Q9UQB8,Q14739,Q86VI3,P27105 6 +Signaling by notch 0.4247987584689247 0.8976702543555056 0.3693613721945215 1.0 1.0 61 P28070,Q9UBV2,P49720,P63208,P49721,Q99436,P25787,P28074,O00231,P67809,Q96J02,Q04721,P61289,Q92542,Q9UL46,P28072,P60900,Q92530,P62333,O75832,Q9HCE1,P42224,P20618 23 +Signalling to erks 0.5320113641174363 0.8860253788134113 0.3756038515927447 1.0 1.0 9 Q16539,P46108,P46109 3 +Rnd1 gtpase cycle 0.4988048033606627 0.8767267147733869 0.3806350927952351 1.0 1.0 17 Q9BXS4,Q8TAA9 2 +Prolonged erk activation events 0.5656338630971323 0.8691650908025215 0.384756838481606 1.0 1.0 5 P46108 1 +Platelet activation signaling and aggregation 0.4104668657784882 0.8539820317108019 0.3931149452996427 1.0 1.0 56 Q8NBM8,Q9NTK5,Q8NCG7,P05067,P46108,Q08380,Q15833,O43852,P07602,Q8NBX0,P13473 11 +Glycogen metabolism 0.5203793040126822 0.8433018218134604 0.3990596641913908 1.0 1.0 10 P10253 1 +Erks are inactivated 0.5584950163219047 0.839060617723238 0.401435294317181 1.0 1.0 5 P30154 1 +Selective autophagy 0.3654750114712549 0.8333979215982587 0.4046203465095346 1.0 1.0 33 P21796 1 +Beta oxidation of hexanoyl coa to butanoyl coa 0.5869271189256016 0.8310173301059529 0.4059638393116298 1.0 1.0 4 P40939 1 +Beta oxidation of lauroyl coa to decanoyl coa coa 0.5869271189256016 0.8310173301059529 0.4059638393116298 1.0 1.0 4 P40939 1 +O linked glycosylation 0.7440787289247667 0.8239563508695306 0.4099643599040781 1.0 1.0 3 O43505 1 +O linked glycosylation of mucins 0.7440787289247666 0.8239563508695306 0.4099643599040781 1.0 1.0 3 O43505 1 +Rac3 gtpase cycle 0.3688978830884016 0.8145847054311751 0.4153100681015831 1.0 1.0 36 O15173,Q8TAA9,O15498,Q9UQB8,Q14739 5 +Signaling by vegf 0.3725714577735874 0.8141166014601752 0.4155781561813592 1.0 1.0 31 Q16539,Q9UQB8,P46108 3 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.7406450719760913 0.8116308809830453 0.4170034660594601 1.0 1.0 3 P30154 1 +Pp2a mediated dephosphorylation of key metabolic factors 0.7406450719760913 0.8116308809830453 0.4170034660594601 1.0 1.0 3 P30154 1 +Downstream signal transduction 0.5156339051536145 0.8109923075462246 0.4173700883267257 1.0 1.0 9 P42224,P46108,P46109 3 +Signaling by pdgf 0.5156339051536145 0.8109923075462246 0.4173700883267257 1.0 1.0 9 P42224,P46108,P46109 3 +Apc c mediated degradation of cell cycle proteins 0.4083469745173648 0.8076645163160987 0.4192837356963266 1.0 1.0 58 P53350,P28070,P49720,P14635,P63208,P49721,Q99436,P25787,P28074,O00231,P30260,P61289,Q9UJX4,Q13042,Q9UL46,P06400,P28072,P60900,Q92530,P06493,P62333,O75832,P20618 23 +Interleukin 4 and interleukin 13 signaling 0.5069398595232618 0.8068948819331164 0.419727047761115 1.0 1.0 12 P09601,P04083 2 +Enos activation 0.7354391417581552 0.7930227387758634 0.4277645747786505 1.0 1.0 3 P35270 1 +Uptake and actions of bacterial toxins 0.5147314306738728 0.789014056892787 0.430103790762774 1.0 1.0 6 P08238,Q16881,Q7L0J3 3 +Nuclear signaling by erbb4 0.5691885347571211 0.7595929851481729 0.447497913517026 1.0 1.0 4 Q92542 1 +Insulin processing 0.5020603553745369 0.7584841056853202 0.4481612246498758 1.0 1.0 10 Q8TAD4,Q9UPT5 2 +Extracellular matrix organization 0.3863775600132304 0.7578717581747209 0.4485277588020429 1.0 1.0 29 O75718,P07237,P05067,O15460,P04632,Q9Y624,Q92542,Q32P28,Q08722 9 +Assembly of the hiv virion 0.8710769230769244 0.7357110117180639 0.461906586790537 1.0 1.0 2 Q9H9H4 1 +G alpha i signalling events 0.4348280499428895 0.7332168096283356 0.4634262044817319 1.0 1.0 23 P07602,P05067,P30154,P04083 4 +Tysnd1 cleaves peroxisomal proteins 0.5618259362864372 0.7303371706813212 0.4651841127633038 1.0 1.0 4 Q15067 1 +Signaling by erbb4 0.4996418353652023 0.7270216272626422 0.4672127071577394 1.0 1.0 7 P16949,Q92542 2 +Interferon alpha beta signaling 0.4968294617498963 0.7258908028151659 0.4679057151633443 1.0 1.0 9 P04439,P10321,P01889 3 +Golgi associated vesicle biogenesis 0.3609245933040069 0.720328084573548 0.4713230169198374 1.0 1.0 31 P11717,Q10567,Q9Y5X3,O43493,Q92572,P50570,P09496,P02792,Q9BXS5,P61966 10 +Metal ion slc transporters 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +Zinc transporters 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +Regulated necrosis 0.4618155021865561 0.7068760122729184 0.4796435321014658 1.0 1.0 18 P49327,Q16543,P07900,O75955,Q9UQN3,O00560,P41440 7 +Signalling to ras 0.5544490027640613 0.7012848145223299 0.4831252885989845 1.0 1.0 4 Q16539 1 +Cobalamin cbl vitamin b12 transport and metabolism 0.5248580190065835 0.6996279954891497 0.4841596544352962 1.0 1.0 5 Q96EY8,P33527,Q99707 3 +Collagen formation 0.4807792791466261 0.6964362413156633 0.4861556733893235 1.0 1.0 13 O75718,O15460,Q32P28 3 +Plasma lipoprotein clearance 0.4767891423613765 0.693412627531308 0.4880506399626123 1.0 1.0 14 O15118,Q8WTV0 2 +Unwinding of dna 0.4905833639443763 0.6919378149078933 0.4889763817467121 1.0 1.0 8 P33993,Q9BRT9 2 +Glycerophospholipid biosynthesis 0.3564237677182812 0.6843673622905657 0.4937432200431719 1.0 1.0 31 P35790,P40939,Q8IV08,Q9NPH0,Q9HCL2 5 +Transport of vitamins nucleosides and related molecules 0.4860369891536801 0.672080912160701 0.501532187472371 1.0 1.0 8 Q8TB61 1 +Rhog gtpase cycle 0.3555535729960968 0.6580195638771337 0.5105255599974241 1.0 1.0 39 Q8TAA9,Q86XL3,O15498,Q13190 4 +Insulin receptor recycling 0.4775001962039095 0.6468897645278764 0.5177032907071515 1.0 1.0 10 Q9Y487,Q15904 2 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4714034576103768 0.6280690812810442 0.52995868654483 1.0 1.0 11 O60725,P49366,Q9HA64 3 +Plasma lipoprotein assembly remodeling and clearance 0.4508191353272155 0.623508743793563 0.532950258150215 1.0 1.0 17 O15118,P61916,P07237,Q8WTV0 4 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4093761871920964 0.6215082943348803 0.5342652388673264 1.0 1.0 24 O14979,Q9UL46,Q00169,P11233,P52597,P14174,Q13126 7 +Intraflagellar transport 0.4611938978560099 0.6176647783950237 0.5367963340487876 1.0 1.0 14 Q9Y366,Q9Y496,Q9BUF5,Q13509,P04350,A0AVF1,Q92973,Q96FJ2,Q96EX3 9 +Cellular response to chemical stress 0.4069461052480579 0.616789774505849 0.5373733974858201 1.0 1.0 71 P07237,P28070,Q9UL46,P00403,Q92530,P30519,P28072,P33527,P09601,P60900,P49721,P20618 12 +Diseases of glycosylation 0.4329846601108661 0.6089552124053345 0.5425541260090587 1.0 1.0 20 P10619,P16278,P06865 3 +Rhoc gtpase cycle 0.3402966419004994 0.6085836855307513 0.5428004209402291 1.0 1.0 34 Q8TAA9,O75955,Q14739,P41440,Q86VI3,P27105,Q13190 7 +Post chaperonin tubulin folding pathway 0.4698926853119743 0.6067542683859504 0.544014001563538 1.0 1.0 9 P04350,Q99426,Q9BUF5,Q13509 4 +Phase ii conjugation of compounds 0.3891989473708422 0.5899305637805655 0.5552372023350132 1.0 1.0 26 P31153,O15217,Q9NUJ1,Q8TB61,Q96KP4 5 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.5244496749064231 0.5863113254300515 0.5576663216525533 1.0 1.0 4 O14975,P51659 2 +Intra golgi traffic 0.4340805779400463 0.5858499055843867 0.55797638349032 1.0 1.0 19 O15498,O00461 2 +Platelet homeostasis 0.4615774125601277 0.5837480109387306 0.5593898606871897 1.0 1.0 11 Q16539,P30154 2 +Striated muscle contraction 0.4654092961368484 0.5807864260135065 0.5613844046251666 1.0 1.0 6 P06753,Q9NYL9,P67936,P09493 4 +Transferrin endocytosis and recycling 0.4608258761172943 0.5803847297188665 0.5616552004582291 1.0 1.0 11 Q9Y487,Q15904 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.6712834718374913 0.5735443741796281 0.5662761629241511 1.0 1.0 3 Q16539,P54619 2 +Phase i functionalization of compounds 0.4466642341599877 0.5636008377689958 0.5730258165467801 1.0 1.0 15 P16435,P07099,P08238,Q6QHF9,O00170,O43169,Q16850 7 +Phosphorylation of the apc c 0.4547977453232179 0.5624290042728021 0.5738237622863247 1.0 1.0 12 P53350,Q9H1A4,P30260,P14635,Q9UJX4,Q96DE5,Q9UJX3,Q13042,P06493 9 +Deadenylation dependent mrna decay 0.342775308818239 0.5546255388050518 0.5791508168505839 1.0 1.0 39 O95628,Q969T7,Q6PGP7,P62312,Q92600,Q96C86,Q15477,P23588,P62310,Q9NQT5 10 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.4835229644747544 0.5361769624822064 0.5918362536382784 1.0 1.0 5 Q16850 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.436691130183043 0.532235190752456 0.5945631126956572 1.0 1.0 16 Q6P179,Q9NZ08,P10321,P01889 4 +Fcgamma receptor fcgr dependent phagocytosis 0.3271115387392709 0.531503446673191 0.59506995351049 1.0 1.0 32 Q9UQB8,P46108 2 +Signaling by interleukins 0.4417039754990019 0.5204152115148795 0.6027742101334703 1.0 1.0 100 P28070,P49720,P46108,O00170,P30153,P51809,P63208,P49721,Q99436,Q13126,P07237,P25787,O00231,P28074,Q15750,P30154,P61289,Q16539,P61088,Q9UL46,P07900,O00459,Q00169,P28072,P09601,P52597,P04083,P60900,P46109,Q92530,P14174,P62333,O75832,O14979,P05067,P42224,P11233,Q15833,P20618 39 +Adp signalling through p2y purinoceptor 12 0.5033866995073801 0.5092938751607504 0.6105462504340462 1.0 1.0 4 P04899,P63096,P08754 3 +Gaba b receptor activation 0.5033866995073801 0.5092938751607504 0.6105462504340462 1.0 1.0 4 P04899,P63096,P08754 3 +Apc c cdc20 mediated degradation of cyclin b 0.44268576286214 0.5081123792277374 0.6113745342121382 1.0 1.0 12 Q12834,Q9H1A4,P30260,P14635,Q9UJX4,Q96DE5,Q9UJX3,Q13042,P06493 9 +Golgi cisternae pericentriolar stack reorganization 0.4443226621123968 0.5018144228083111 0.615798066781927 1.0 1.0 10 P53350,Q9H0U4,Q9H8Y8,P06493 4 +Signaling by ptk6 0.4422973763875238 0.4988217334845061 0.6179049752677601 1.0 1.0 11 P46108,Q07666 2 +Energy dependent regulation of mtor by lkb1 ampk 0.4440677966101729 0.4941247294741072 0.6212180940656302 1.0 1.0 7 Q9Y376,P54619,P54646,Q15382,Q6IAA8,P42345 6 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6458515204787949 0.4930687775680064 0.6219639911651846 1.0 1.0 3 Q9HCE1 1 +Dap12 signaling 0.4978448275861976 0.489632709518855 0.62439382604968 1.0 1.0 4 P62993,P19174,O00459 3 +Ub specific processing proteases 0.3968509374169167 0.488150683552889 0.6254431132532035 1.0 1.0 75 Q96FW1,P28070,P28074,P21796,Q9UL46,Q92530,P45880,Q9Y277,P28072,P60900,P49721,P20618 12 +Autophagy 0.3573067991858469 0.4865847435993507 0.62655263734618 1.0 1.0 52 P21796,Q9NS69,Q9UQN3,Q8N4H5,Q9H9H4,P13473 6 +Diseases associated with o glycosylation of proteins 0.7870769230769267 0.4857935479007231 0.6271135493450686 1.0 1.0 2 O43505 1 +Signaling by notch2 0.7870769230769055 0.4857935479006661 0.627113549345109 1.0 1.0 2 Q92542 1 +Notch2 activation and transmission of signal to the nucleus 0.7870769230769055 0.4857935479006661 0.627113549345109 1.0 1.0 2 Q92542 1 +Activation of the pre replicative complex 0.4194675661354941 0.4857752630069583 0.6271265148277085 1.0 1.0 18 P33992,P49642,P56282,P33993,Q14181,Q9Y619 6 +Pre notch processing in golgi 0.4698448525274316 0.4847491630884623 0.6278542879202529 1.0 1.0 5 Q9UBV2 1 +Er quality control compartment erqc 0.6404991682782777 0.476720979199165 0.6335608218103355 1.0 1.0 3 Q9UBV2 1 +Uptake and function of diphtheria toxin 0.4938025827661388 0.4754644467360401 0.634455968544489 1.0 1.0 4 P08238,Q16881 2 +Ksrp khsrp binds and destabilizes mrna 0.431237569120987 0.4663999896084932 0.6409292189395135 1.0 1.0 13 Q16539,Q92945 2 +Adora2b mediated anti inflammatory cytokines production 0.4363776886314111 0.463624486468081 0.6429168077431977 1.0 1.0 7 P10644 1 +Vxpx cargo targeting to cilium 0.4326687850487004 0.4500391819660214 0.6526821885145306 1.0 1.0 9 Q92538,Q9UPT5 2 +Alpha oxidation of phytanate 0.4584260982549884 0.4430701814886252 0.6577149724451519 1.0 1.0 5 P51648 1 +Interferon gamma signaling 0.4250974732642689 0.4393316574946611 0.6604212387352566 1.0 1.0 13 P19474,P04439,P10321,P01889 4 +Amyloid fiber formation 0.4298275708331525 0.4380704774664159 0.661335194682529 1.0 1.0 7 P05067 1 +Diseases of mitotic cell cycle 0.4225247835015813 0.4376849709267674 0.6616146656316935 1.0 1.0 14 P11802,P06400,Q9H1A4,P30260,Q00534,Q9UJX4,Q16763,Q96DE5,Q9UJX3,Q13042 10 +Rhob gtpase cycle 0.365067767906897 0.435675719305224 0.6630720247495876 1.0 1.0 26 Q8TAA9,O75955,P41440,Q86VI3,P27105 5 +Sulfur amino acid metabolism 0.4265726821509447 0.4319598259725084 0.6657706119205624 1.0 1.0 11 Q13126 1 +Trna modification in the nucleus and cytosol 0.4209224721696508 0.4305344868006836 0.6668068856475915 1.0 1.0 14 Q9UET6,Q9UJA5,O75648 3 +Copi mediated anterograde transport 0.3549144589830426 0.4284880669262343 0.6682958196068107 1.0 1.0 55 Q9H0U4,O15498,Q8N6T3,P24390,Q92538,Q13509,O43731,P04350,Q9Y3B3,Q9UJW0,Q13190,P61163 12 +Constitutive signaling by akt1 e17k in cancer 0.4772167487684636 0.4189645439843864 0.6752420449302399 1.0 1.0 4 P31751,P49841,P42345 3 +Metalloprotease dubs 0.423915263443968 0.4177074248152701 0.676161043075 1.0 1.0 6 Q15018 1 +Rho gtpases activate ktn1 0.4242873898178302 0.4167824950584709 0.6768375074163 1.0 1.0 7 Q9NSK0,P84095,P33176 3 +Lipophagy 0.4762931034482659 0.4158997007563243 0.6774833984981845 1.0 1.0 4 P11142,P54619,P54646 3 +Kinesins 0.3787793031398661 0.4025760282207076 0.6872601475166573 1.0 1.0 23 Q9H0H5,Q9Y496,Q9NSK0,P33176,Q13509,Q8NI77,Q9BUF5,P04350,P52732 9 +Activated tak1 mediates p38 mapk activation 0.4690402371843154 0.3921505921911393 0.6949469479291535 1.0 1.0 4 Q16539,P61088 2 +Nod1 2 signaling pathway 0.4155696606347183 0.3822746003549686 0.7022576926108257 1.0 1.0 9 Q16539,P42575,P61088,Q15750 4 +Synthesis of dna 0.3920766477456149 0.3802751879363939 0.7037411516942071 1.0 1.0 81 P28070,P49720,Q14181,P63208,P49721,Q99436,P25787,O00231,P49642,P28074,P33993,P30260,P55036,P61289,P41440,Q9Y619,Q9UJX4,Q13042,Q9UL46,P33992,P56282,P28072,Q9BRT9,P60900,Q92530,Q15054,P62333,O75832,P12004,P20618 30 +Hs gag biosynthesis 0.7433846153846202 0.3729188303077451 0.7092088567727097 1.0 1.0 2 Q93063 1 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4115287304754492 0.370425981947903 0.711065117702717 1.0 1.0 11 P06400,Q9H1A4,P30260,Q9UJX4,Q96DE5,Q9UJX3,Q13042 7 +Endosomal sorting complex required for transport escrt 0.4109407248058029 0.368074622762566 0.7128175927355065 1.0 1.0 11 Q9UQN3,Q9H9H4 2 +Cholesterol biosynthesis 0.4043118508304015 0.3676437336039767 0.7131389004697533 1.0 1.0 15 P04035,Q15392,P37268,Q14739,Q16850 5 +Met activates rap1 and rac1 0.4085061832077342 0.361253120825975 0.7179102348203652 1.0 1.0 6 P46108 1 +Transcriptional activation of mitochondrial biogenesis 0.4071768853178157 0.3570307952022863 0.7210687517748764 1.0 1.0 12 P48735 1 +Darpp 32 events 0.4071724887931991 0.3530897213196978 0.7240211784486505 1.0 1.0 7 P30154 1 +Piwi interacting rna pirna biogenesis 0.4070625784951002 0.3504527281022629 0.7259989608772415 1.0 1.0 10 Q9Y2W6,P61218 2 +Signaling by insulin receptor 0.3977077469324248 0.3497855159836588 0.726499669802894 1.0 1.0 16 Q9Y487,Q15904 2 +Translocation of slc2a4 glut4 to the plasma membrane 0.3044838005457722 0.3409144147819673 0.7331680127660025 1.0 1.0 33 Q8IYI6,Q9Y496,Q13509,P04350,Q9UPT5,Q9UIQ6 6 +Cilium assembly 0.3579115218057412 0.3373730071684728 0.7358357302598675 1.0 1.0 64 P53350,Q7Z4H7,P04350,P30153,Q9H6D7,Q9UPT5,O43805,Q9H0F7,A6NIH7,Q9Y496,Q92538,O94927,Q96CS2,Q8IYI6,P07900,Q13509,P61163,P06493,Q15691,Q10713,Q13561,Q15019,Q9Y366,A0AVF1,Q92973,Q96EX3 26 +Synthesis of very long chain fatty acyl coas 0.4032144433680225 0.3353771581625249 0.7373405963667936 1.0 1.0 9 Q9NZ01,Q9UKU0 2 +Suppression of phagosomal maturation 0.4009244992295717 0.330687469024695 0.7408805685526405 1.0 1.0 7 Q9UI12,Q14974,O14964,P52294,P20339,Q9H267 6 +Beta catenin phosphorylation cascade 0.4004056684092019 0.3262644354843014 0.7442242936248735 1.0 1.0 8 P30154,P30153,Q16537 3 +Signaling by ctnnb1 phospho site mutants 0.4004056684092019 0.3262644354843014 0.7442242936248735 1.0 1.0 8 P30154,P30153,Q16537 3 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.4004056684092019 0.3262644354843014 0.7442242936248735 1.0 1.0 8 P30154,P30153,Q16537 3 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3991708803262011 0.3204502530291664 0.7486270358674234 1.0 1.0 10 Q12834,Q9H1A4,P30260,Q9UJX4,Q96DE5,Q9UJX3,Q13042 7 +Neddylation 0.3785505652596617 0.3189307783565877 0.7497790043615493 1.0 1.0 78 Q9Y6G5,P28070,Q9NWX5,P49720,Q9UBW8,P49721,Q99436,P25787,O00231,P28074,Q92905,Q8IWE4,P61289,Q9BT78,Q9H0A8,Q9UL46,P28072,Q9BTE7,P60900,Q92530,Q92564,P62333,O75832,P20618 24 +Netrin 1 signaling 0.3948394859336972 0.3123984061825429 0.754737761486302 1.0 1.0 13 Q16539,Q00169 2 +Negative regulators of ddx58 ifih1 signaling 0.3929121725731824 0.3026842654303665 0.7621304900028489 1.0 1.0 7 Q14258,Q86UT6,Q13526,Q15366,Q96J02,P61086 6 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7110769230769266 0.299109782360646 0.7648562825354932 1.0 1.0 2 P49327 1 +Neutrophil degranulation 0.5120682118720968 0.2922333054525378 0.7701082484262378 1.0 1.0 172 P06280,P04066,P30519,P09960,P10253,P07602,P27105,P15586,P16278,Q13510,P10619,P42785,Q92542,P02792,Q9NQX7,O75874,P61916,Q99536,P17900,O00560,Q93050,P04080,Q92820,P10321,O15260,P01889,Q9BTY2,O00462,O00584,P20618,P13473 31 +Ion channel transport 0.3126304704207698 0.2914847556256651 0.7706806012063725 1.0 1.0 30 Q9HD20,P30626,Q9Y487,Q15904,Q93050,P27105 6 +P38mapk events 0.5702340884016157 0.2852815517837411 0.7754284454091764 1.0 1.0 3 Q16539 1 +Pre notch processing in the endoplasmic reticulum 0.5667243930276766 0.2769996081730011 0.7817804070111736 1.0 1.0 3 Q04721 1 +Synthesis of substrates in n glycan biosythesis 0.3850913972983991 0.2741722479894478 0.7839522541395045 1.0 1.0 13 P10619 1 +Protein localization 0.3778380243326046 0.2581245062076409 0.7963108190592767 1.0 1.0 83 O75874,Q13505,Q10713,P21796,P05067,Q9NS69,Q6QHF9,Q99595,P51648,P46379,Q8N4H5,P09601,Q13190,Q9Y584 14 +Fatty acyl coa biosynthesis 0.3648343989427702 0.2436792747341133 0.8074792259534145 1.0 1.0 19 P50897,Q9UMR5,Q9UKU0 3 +Role of abl in robo slit signaling 0.3968348400949087 0.2433161037129647 0.8077605302349227 1.0 1.0 5 Q9Y6N7 1 +Rhoh gtpase cycle 0.338200016264973 0.2426479981173387 0.808278095032313 1.0 1.0 25 Q9BXS4,Q8TAA9 2 +Notch4 intracellular domain regulates transcription 0.6821538461538501 0.2408455190326167 0.8096748487330396 1.0 1.0 2 Q04721 1 +Intra golgi and retrograde golgi to er traffic 0.4110233998011666 0.2387729032664736 0.8112816826223503 1.0 1.0 106 O43493,P24390,O43731,P04350,P20645,Q9UJW0,Q10472,Q9P2W9,Q9Y496,Q8N6T3,Q92538,P52732,Q9H0H5,Q7Z6M1,P11717,O60499,Q9NSK0,Q13509,Q9Y3B3,Q9UIL1,Q8TD16,Q13190,P61163,Q9H0U4,O15498,O00461,O15260,Q15102,Q8N2H4 29 +Golgi to er retrograde transport 0.3614929739279365 0.2354303312521766 0.8138747466385685 1.0 1.0 75 P24390,O43731,P04350,Q9UJW0,Q10472,Q9P2W9,Q9Y496,Q8N6T3,Q92538,Q9H0H5,P52732,Q9NSK0,Q13509,Q9Y3B3,Q8TD16,P61163,Q9H0U4,O15260,Q15102 19 +Mapk targets nuclear events mediated by map kinases 0.3726755282314159 0.2315762254837331 0.81686717489918 1.0 1.0 8 P30154 1 +Erk mapk targets 0.3726755282314159 0.2315762254837331 0.81686717489918 1.0 1.0 8 P30154 1 +Signaling by kit in disease 0.3925220133765034 0.2312134237389881 0.8171490018934215 1.0 1.0 5 P42224 1 +Stimuli sensing channels 0.3739766194891447 0.2298049552884598 0.8182433340063064 1.0 1.0 11 P27105,P30626,P51797 3 +Transcriptional regulation by ventx 0.3697874745636291 0.2203931229637394 0.8255650008312925 1.0 1.0 14 Q9HCE1,Q9H1A4,P42771,P30260,Q9UJX4,Q16763,Q96DE5,Q9UJX3,Q13042 9 +Rac2 gtpase cycle 0.2979329347551597 0.2173509124559152 0.8279348828956745 1.0 1.0 39 Q13505,O15173,Q8TAA9,Q86XL3,Q14739 5 +Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.369938336997524 0.2159728864507875 0.8290088822841191 1.0 1.0 11 Q10567,P04439,P61966 3 +Raf activation 0.3676312943065417 0.2124437662261559 0.8317608444178157 1.0 1.0 14 Q6UWU4 1 +Ldl clearance 0.3686861478322643 0.211815170834932 0.8322512324442706 1.0 1.0 12 P35610,P61916,O15118 3 +Respiratory electron transport 0.3204446723219582 0.2063079011319798 0.8365504070820609 1.0 1.0 53 O75380,P00403,O43676,Q8N183,P22695,Q9P0J0,Q9UDW1,O96000,O95168,Q9BU61,O95182,Q9Y6M9,Q8TB37,P21912,O75306 15 +Signaling by hippo 0.3589650378526652 0.2002257947896008 0.8413039943049405 1.0 1.0 6 Q4VCS5 1 +Integrin cell surface interactions 0.3807783001393592 0.1996923594189616 0.8417211897231907 1.0 1.0 5 Q9Y624,Q08722 2 +Adenylate cyclase inhibitory pathway 0.5281625115420171 0.1951334144869586 0.8452885043712797 1.0 1.0 3 P04899,P63096 2 +Pyruvate metabolism and citric acid tca cycle 0.287534020780536 0.1941134026751664 0.8460870874106596 1.0 1.0 35 P21796 1 +Interleukin 21 signaling 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 1.0 2 P42224 1 +Interleukin 9 signaling 0.6523076923076779 0.1889593853201696 0.8501246490919454 1.0 1.0 2 P42224 1 +Parasite infection 0.3373298947662188 0.1879190850430026 0.8509400815612551 1.0 1.0 23 Q9UQB8 1 +Cyclin d associated events in g1 0.3611537830444307 0.1862312125051478 0.8522634480494036 1.0 1.0 12 P11802,P63151,P06400,P30154,P30153 5 +Anchoring of the basal body to the plasma membrane 0.2796705918884375 0.1765814662147604 0.8598371531200688 1.0 1.0 32 P53350,Q96CS2,Q7Z4H7,Q15691,Q13561,Q15019,P07900,P61163,P04350,O94927,Q9H6D7,O43805,P06493 13 +Gpvi mediated activation cascade 0.3693062724644911 0.1710008316068313 0.8642231116994707 1.0 1.0 5 P84095 1 +Ros and rns production in phagocytes 0.3511317900788402 0.1616432195208694 0.8715868205857409 1.0 1.0 9 Q9Y487 1 +Adrenaline noradrenaline inhibits insulin secretion 0.5032317636195798 0.1514832568225476 0.8795945175422217 1.0 1.0 3 P04899,P63096 2 +The role of nef in hiv 1 replication and disease pathogenesis 0.3503386178581069 0.150950361295176 0.8800148730374138 1.0 1.0 13 Q10567,P04439,P61966 3 +Tryptophan catabolism 0.6261538461538505 0.1505357446397698 0.8803419518888667 1.0 1.0 2 Q6YP21 1 +Pten regulation 0.3275245781496172 0.1430264998486018 0.8862692524961817 1.0 1.0 63 O95983,O75832,P28070,P25787,P28074,O00231,Q9UL46,Q9HC52,Q92530,Q9HCE1,P28072,P60900,P49721,P20618,Q99436 15 +Tnf signaling 0.3399282693417859 0.1415301575197343 0.887451137562189 1.0 1.0 7 O95429 1 +Recycling of eif2 gdp 0.339351864502977 0.1400344567759708 0.8886327660351954 1.0 1.0 7 Q9UI10 1 +Pentose phosphate pathway 0.3351817621688232 0.1363721216793917 0.8915271114399064 1.0 1.0 6 O95336,P37837,P11413,Q96G03,P52209 5 +Cd28 dependent pi3k akt signaling 0.4890735610957262 0.1299948809785485 0.8965704767127356 1.0 1.0 3 P31751,O00459 2 +Irak1 recruits ikk complex 0.488483341186054 0.1291506545259458 0.8972384410831855 1.0 1.0 3 P61088 1 +Fgfr2 alternative splicing 0.3350595526872264 0.1221397247244712 0.902788361599947 1.0 1.0 19 P61218,P52298,P52597 3 +Regulation of pten localization 0.597538461538468 0.1159310875342688 0.907707157514874 1.0 1.0 2 P46934 1 +Notch hlh transcription pathway 0.357758620689643 0.115502355388167 0.9080469536434244 1.0 1.0 4 Q13573,Q04721,Q13547 3 +Diseases of immune system 0.4770698676515896 0.1136275465534503 0.909533049778755 1.0 1.0 3 O14920,P09429 2 +Akt phosphorylates targets in the cytosol 0.4770698676515895 0.1136275465534503 0.909533049778755 1.0 1.0 3 P31751,P49841 2 +Met promotes cell motility 0.3300972617738871 0.1103803195800601 0.9121077604475548 1.0 1.0 8 P46108 1 +Constitutive signaling by overexpressed erbb2 0.3545464221512114 0.1103004488719831 0.912171101288972 1.0 1.0 4 Q16543 1 +Eph ephrin mediated repulsion of cells 0.3351095388109669 0.108967664835416 0.9132281373006512 1.0 1.0 11 Q92542 1 +Polo like kinase mediated events 0.353173899251711 0.1081271485674069 0.9138948329582544 1.0 1.0 4 P53350 1 +Regulation of commissural axon pathfinding by slit and robo 0.4662461806300963 0.100295101118395 0.920110046624736 1.0 1.0 3 Q9Y6N7 1 +Signaling by erbb2 in cancer 0.3352114160057272 0.0986366451275207 0.9214267732764638 1.0 1.0 5 Q16543 1 +Signaling by erbb2 ecd mutants 0.3352114160057272 0.0986366451275207 0.9214267732764638 1.0 1.0 5 Q16543 1 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.3316907914998471 0.0922905785974393 0.9264671736136928 1.0 1.0 5 P05141,P12235,P36404,P12236 4 +S phase 0.3675088860183199 0.0919667743153542 0.9267244379396826 1.0 1.0 93 P11802,P28070,P49720,Q14181,P63208,P49721,Q99436,P25787,O00231,P49642,P28074,P33993,P30260,P55036,P61289,P41440,Q9Y619,Q9UJX4,Q13042,Q9UL46,P33992,P56282,P06400,P28072,Q9BRT9,P60900,Q92530,Q15054,P62333,O75832,P12004,P20618 32 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.3284172307953256 0.0917529506566745 0.9268943262424848 1.0 1.0 18 Q9UHV9,Q9BUF5,P61758,Q13509,P04350,Q9NQP4,Q99471 7 +G2 m dna replication checkpoint 0.4566842781216507 0.0896115461500304 0.9285959088235316 1.0 1.0 3 P06493 1 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.4527546937519286 0.0855111143469884 0.9318550598654174 1.0 1.0 3 P28482,P31751 2 +Mitotic g2 g2 m phases 0.3614420640293624 0.0839686367745152 0.933081367906118 1.0 1.0 90 P53350,Q7Z4H7,P28070,P49720,P04350,P14635,Q9H6D7,P30153,O43805,P49721,Q9Y570,Q99436,P25787,O00231,P28074,P30154,O94927,P61289,Q96CS2,Q9UL46,P08238,P07900,Q13509,P28072,P60900,Q92530,P61163,P06493,P62333,O75832,Q15691,Q13561,P63151,Q9BSJ2,P20618 35 +Phospholipid metabolism 0.2939134555878699 0.0810649546405255 0.935390296074846 1.0 1.0 49 P35790,Q10713,Q8NCC3,P40939,Q8IV08,Q9NPH0,Q9HCL2 7 +Deubiquitination 0.3637638070560762 0.0792047223928164 0.9368697884692812 1.0 1.0 92 P28070,P21796,P45880,Q9NWV8,P49721,Q99436,P25787,O00231,P28074,P51784,P54725,Q9Y277,Q8NB78,P61289,Q96K76,Q96FW1,Q9UL46,P28072,P60900,Q92530,P06493,O75832,P54727,P20618,Q15018 25 +Fgfr2 mutant receptor activation 0.3246917846498965 0.0779352903728264 0.937879527113992 1.0 1.0 12 P52298 1 +Signaling by fgfr2 iiia tm 0.3246917846498965 0.0779352903728264 0.937879527113992 1.0 1.0 12 P52298 1 +Ikk complex recruitment mediated by rip1 0.3230674468740347 0.077638838575253 0.9381153468927144 1.0 1.0 5 O14920,Q6SZW1,O15111,P61088 4 +Polymerase switching 0.3259902473231013 0.0766516720547095 0.9389006514792168 1.0 1.0 15 P41440,Q15054,Q14181,P12004 4 +Tcf dependent signaling in response to wnt 0.3180122888217312 0.0751938097981918 0.9400605094781008 1.0 1.0 64 P28070,Q9UL46,Q92530,P30154,P28072,P60900,P49721,P20618 8 +Dna replication 0.3535308748925706 0.0746818741696351 0.9404678297105882 1.0 1.0 86 P28070,P49720,Q14181,P63208,P49721,Q99436,P25787,O00231,P49642,P28074,P33993,P30260,P55036,P61289,P41440,Q9Y619,Q9UJX4,Q13042,Q9UL46,P33992,P56282,P28072,Q9BRT9,P60900,Q92530,Q15054,P62333,O75832,P12004,P20618 30 +Transcriptional regulation by runx1 0.3244483776156759 0.0743442528620226 0.9407364657419132 1.0 1.0 68 O75832,P28070,P25787,P28074,O00231,Q9UL46,Q9HC52,Q92530,Q9HCE1,P20618,P28072,P60900,P49721,Q9HCL2,Q99436,Q9C005 16 +Methylation 0.3053903277803615 0.0706146191388611 0.9437044750687892 1.0 1.0 6 P31153,P21964 2 +Ticam1 rip1 mediated ikk complex recruitment 0.3229679802955554 0.0675989866519045 0.9461048620905184 1.0 1.0 4 O14920,O15111,P61088 3 +Signaling by wnt in cancer 0.3162780150587985 0.0661357085691856 0.9472697817449334 1.0 1.0 10 P56545,P30154,P30153,Q16537 4 +Defects in cobalamin b12 metabolism 0.3214981048022556 0.0659712207583309 0.9474007380325824 1.0 1.0 4 Q96EY8,Q99707 2 +Transport of small molecules 0.4561238474459345 0.0651007402012334 0.9480937910893013 1.0 1.0 157 Q70HW3,P21796,O15118,P28070,Q99797,P30519,Q9UBV2,P45880,Q15904,P33527,P49721,P08183,P27105,P07237,P28074,Q9NUT2,Q8TAD4,Q9Y277,P35610,Q8WTV0,P02792,Q9HD20,P61916,Q9UL46,O00400,Q9UBX3,Q9Y487,P28072,P09601,P60900,Q92530,Q93050,Q10713,P10644,P30626,Q8TB61,P20618 37 +Interleukin 15 signaling 0.5350769230769338 0.0649995075064543 0.948174392380018 1.0 1.0 2 P40763 1 +Signaling by fgfr4 in disease 0.5350769230769282 0.0649995075064509 0.9481743923800208 1.0 1.0 2 P19174 1 +Phenylalanine metabolism 0.5141538461538476 0.0543453923256221 0.956659985118416 1.0 1.0 2 Q7L266 1 +Rora activates gene expression 0.4121268082486972 0.0522712278736265 0.9583125787959292 1.0 1.0 3 P50416,Q86X55 2 +Microrna mirna biogenesis 0.3152207471441862 0.0508459779208225 0.9594482531533332 1.0 1.0 13 O15514,P19388,P61218,P62826,Q8WYQ5,P62487,Q9UPY3,P19387,O75569,P62875,Q9HAV4,P30876 12 +G beta gamma signalling through pi3kgamma 0.5030769230769236 0.0497651228958572 0.960309560126003 1.0 1.0 2 P31751 1 +Signaling by fgfr2 in disease 0.3151739347961507 0.0481310822903809 0.96161177481836 1.0 1.0 14 P52298 1 +Nef and signal transduction 0.4975384615384656 0.0477233684918973 0.961936709955678 1.0 1.0 2 Q13177 1 +Gap junction trafficking and regulation 0.3087594759134972 0.0441137257572047 0.964813751863911 1.0 1.0 11 P50570,P04350,Q13509 3 +Disorders of transmembrane transporters 0.3304285270127188 0.0434485011636134 0.9653440158419728 1.0 1.0 75 P28070,Q9UL46,Q92530,Q9UBV2,O00400,Q9BTX1,P28072,Q8NFH5,P60900,P49721,P20618 11 +Ikba variant leads to eda id 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +Runx3 regulates p14 arf 0.4732307692307687 0.0404903049334568 0.9677022362468648 1.0 1.0 2 P42771 1 +Signal attenuation 0.4655384615384765 0.0387175429849037 0.9691155866165436 1.0 1.0 2 P62993 1 +Signaling by mapk mutants 0.46553846153846 0.0387175429849004 0.9691155866165464 1.0 1.0 2 Q99956 1 +Mapk family signaling cascades 0.348713769838941 0.0384335613072011 0.9693420026874406 1.0 1.0 87 Q6UWU4,Q96P70,Q9UL46,P28070,Q9HCE1,Q92530,P20618,P30154,P49356,P28072,O60725,P49721,P60900 13 +Notch3 intracellular domain regulates transcription 0.384746357062616 0.0380250133674312 0.9696677386636294 1.0 1.0 3 P42224 1 +Serine biosynthesis 0.4544615384615548 0.0365353343444673 0.970855504774587 1.0 1.0 2 O43175 1 +Hiv transcription initiation 0.3112894342914247 0.0354845963081025 0.971693329005884 1.0 1.0 16 P61218,Q92804 2 +Galactose catabolism 0.4353846153846121 0.0336544519977791 0.9731527004186452 1.0 1.0 2 Q96G03 1 +Atf4 activates genes in response to endoplasmic reticulum stress 0.3061728395061759 0.0336392789505734 0.973164799907826 1.0 1.0 12 Q92945,Q96B26,P08243,Q06265,Q15024,Q9Y2L1,Q9Y3B2,Q5RKV6,O95453,Q9NQT5,Q13868 11 +Synthesis of ip3 and ip4 in the cytosol 0.420307692307698 0.0320173940921254 0.9744581795288908 1.0 1.0 2 P19174 1 +Inactivation of csf3 g csf signaling 0.2887138229453713 0.0314815658484584 0.9748854931799824 1.0 1.0 5 Q15369,Q15370,P42224 3 +Pi5p regulates tp53 acetylation 0.364112034472151 0.0306930154475553 0.975514361405261 1.0 1.0 3 Q8TBX8,Q13526 2 +G alpha z signalling events 0.2873421619956863 0.0300249667790212 0.9760471415339764 1.0 1.0 5 P04899,Q9UBI6,P63096,P08754 4 +Laminin interactions 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 +Regulation of tp53 activity through association with co factors 0.3640000000000027 0.0290610830282848 0.9768158739230484 1.0 1.0 2 P31751 1 +G alpha 12 13 signalling events 0.294480419364802 0.0278914887816151 0.977748696772547 1.0 1.0 9 Q13464,Q92888,Q12802,Q9UBI6,Q9H8V3,Q14155,Q14344,O75116 8 +Response of eif2ak1 hri to heme deficiency 0.3487226839027439 0.0267412435687508 0.9786661172724278 1.0 1.0 3 P05198,P08243 2 +Perk regulates gene expression 0.3063619518221068 0.0265375939343107 0.9788285485256832 1.0 1.0 14 Q92945,Q96B26,P08243,P20042,Q06265,Q15024,P05198,Q9Y2L1,Q9Y3B2,Q5RKV6,O95453,Q9NQT5,Q13868 13 +Anti inflammatory response favouring leishmania parasite infection 0.301523290340341 0.0236997888611266 0.9810920744239012 1.0 1.0 12 Q16539 1 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.3219452139119777 0.0222163879861454 0.9822753450944766 1.0 1.0 3 P18887,P49916 2 +Protein folding 0.2616185997498491 0.0137958433642768 0.9889928587337296 1.0 1.0 37 P51784,Q13509,Q15477,P04350,Q9NQP4,P04062,Q9UHV9 7 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3023477198612959 0.0121591088315249 0.9902986738378206 1.0 1.0 18 P10619 1 +Toll like receptor tlr1 tlr2 cascade 0.3009541369458985 0.0084169343914511 0.9932843372948104 1.0 1.0 18 P05067,P30154 2 +Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.2886918704564712 0.00459616932044 0.9963328003718492 1.0 1.0 11 Q92973 1 +Condensation of prometaphase chromosomes 0.2790625963614003 0.0025269890985261 0.9979837565588144 1.0 1.0 9 Q15003,Q9NTJ3,O95347,P19784,P67870,P14635,Q9BPX3,P06493 8 +Sema3a pak dependent axon repulsion 0.2726989663598766 0.0010520659656673 0.9991605729639002 1.0 1.0 8 P08238,O14786 2 +Death receptor signalling 0.2912536413723529 0.0008384836014317 0.9993309869583232 1.0 1.0 23 P52565,P49327,P42575,O95429,P63244,Q92542 6 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..564fb074e4326928ee74553c7f6cfb1f0d72b917 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through pi3k", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodeling of dag and tag", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pou5f1 oct4 sox2 nanog repress genes related to differentiation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANO10", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APIP", "APLP2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRIP", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAZ1B", "BCAP31", "BCAS2", "BCKDHA", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD8", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "C6orf89", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CENPE", "CENPF", "CENPI", "CENPU", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIT", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLNS1A", "CLSPN", "CLTA", "CLTC", "CLU", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "COG2", "COG3", "COG4", "COG5", "COG7", "COLGALT1", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUX1", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHHADH", "EHMT2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTB", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHDC", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAGED2", "MAIP1", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MARC1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL14", "METTL3", "MFAP1", "MFGE8", "MFN1", "MFN2", "MGAT1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "MYO9B", "NAA35", "NADK2", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA2", "PNPLA6", "POFUT1", "POGLUT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCOC", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SPAG9", "SPC25", "SPCS2", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX16", "STX18", "STX5", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE1", "SYNE2", "SYS1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126B", "TMEM59", "TMEM87A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TTC26", "TTC37", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR2", "UBR4", "UBTF", "UBXN7", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDCP", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WRN", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZCCHC11", "ZFYVE16", "ZMYM2", "ZNF131", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ABHD10", "ABRAXAS2", "ACOX1", "ACP6", "ACSL6", "ACTR1A", "AIP", "AKAP13", "AKT2", "ALDH3A2", "AMOT", "ANAPC1", "ANAPC16", "ANAPC5", "ANAPC7", "ANKLE2", "ANXA1", "AP1B1", "AP1M1", "AP1S1", "AP3S1", "APLP2", "APP", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARL2", "ARL6", "ASAH1", "ASB6", "ASNA1", "ASNS", "ASRGL1", "ATP13A1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1H", "B3GAT3", "B4GAT1", "BABAM1", "BAG4", "BAG6", "BAIAP2", "BICD2", "BRAP", "C6orf89", "CAB39", "CALU", "CAPNS1", "CARM1", "CASP2", "CBX8", "CCNB1", "CD47", "CDC16", "CDC20", "CDC27", "CDC34", "CDC37", "CDK1", "CDK4", "CDK6", "CDKN2A", "CERS2", "CHKA", "CHMP2B", "CHST14", "CHUK", "CLCN6", "CLTA", "CNDP2", "CNOT4", "CNOT9", "COMMD10", "COMMD4", "COMT", "COPS4", "COPS5", "COPS7A", "COX2", "CPT1A", "CRK", "CRKL", "CRTAP", "CSGALNACT2", "CSNK2A2", "CSNK2B", "CSTB", "CTBP2", "CTSA", "CYB5B", "CYP51A1", "DAGLB", "DCPS", "DCTN2", "DCTN4", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DGCR8", "DHCR24", "DHFR", "DHPS", "DICER1", "DIS3", "DNAJB11", "DNM2", "DPY30", "DUSP9", "DYNLL2", "ECE1", "ECT2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF4B", "ELOB", "ELOC", "ENSA", "EPHX1", "EPN1", "ERAP1", "ERAP2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "F11R", "FASN", "FDFT1", "FKBP14", "FLOT1", "FN3KRP", "FNTB", "FTL", "FTSJ1", "FUCA1", "FUCA2", "G6PD", "GAA", "GALNT1", "GBA", "GBF1", "GET4", "GGH", "GINS4", "GLA", "GLB1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNS", "GOLIM4", "GORASP2", "GPAM", "GRB2", "GSK3B", "GSTA4", "HADHA", "HAUS1", "HAUS4", "HAUS5", "HAUS6", "HDAC1", "HEXA", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGCR", "HMOX1", "HMOX2", "HNRNPDL", "HNRNPF", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA8", "ICMT", "IDH1", "IDH2", "IFT52", "IGF2R", "IKBKB", "IMPA1", "IPO9", "IQGAP3", "ITCH", "ITGAV", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIF11", "KIF18A", "KIF3A", "KIF5B", "KLC4", "KPNA1", "KPNB1", "KYAT3", "LAMP2", "LAMTOR1", "LBR", "LGALS3BP", "LIG3", "LNPEP", "LSM3", "LSM6", "LTA4H", "M6PR", "MALT1", "MANBA", "MAPK1", "MAPK14", "MAPRE1", "MAT2A", "MBD3", "MCM5", "MCM7", "METAP1", "MIF", "MIPEP", "MMAB", "MOV10", "MTAP", "MTOR", "MTR", "MTX1", "NAGLU", "NCAPG", "NCAPH", "NCBP2", "NCSTN", "NDC1", "NDUFA13", "NDUFA7", "NDUFAF2", "NDUFAF3", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NDUFS6", "NECAP2", "NEDD4", "NF1", "NLRX1", "NOTCH2", "NPC1", "NPC2", "NRP1", "NT5C3B", "NUBPL", "NUCB1", "NUDT9", "NUP35", "OLA1", "OS9", "OTUB1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PAFAH1B3", "PAK2", "PAOX", "PARN", "PCBP2", "PCNA", "PCYOX1L", "PEBP1", "PEX3", "PFDN2", "PFDN4", "PFDN5", "PFN1", "PGD", "PGLS", "PGM2", "PGRMC2", "PHGDH", "PHKA1", "PIK3R2", "PIN1", "PIP4K2C", "PITPNA", 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0000000000000000000000000000000000000000..83b7c74d84256d87f9c8314f5fbc2902aaa5cab3 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycosaminoglycan degradation 3 6 2.447075314875302 0.0144020740564194 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 5.144643156630706e-05 0.0561990347849709 0.0057815105752346 0.0001472775053537 0.0020484591711739 +Degradation pathway of sphingolipids including diseases 4 6 2.3668431808064576 0.0179405327739683 3.645631067961165 6.432038834951456 0.0687547082162972 0.1728701573933007 1.3368036576958324 0.5554170290527195 1.9109030412897592 0.2451148181788838 1.3684212150481574e-05 1.0 0.0841007109914387 3.972711663948022e-05 2.9438380117440665e-05 +Sphingolipid metabolism in senescence 6 12 2.0949415182319857 0.0361761915123384 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.0007837622690909 0.0053672672920639 0.0013656945298514 0.0021324559374895 7.964767423511622e-05 +Sphingolipid metabolism overview 4 7 2.065562902466933 0.0388697703378642 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.0035723772978945 0.0029386578360865 0.0005470061355849 0.0075942890928168 0.0010425648425055 +Sphingolipid metabolism integrated pathway 4 7 2.065562902466933 0.0388697703378642 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0049532633265819 0.0036723611473879 0.0007685743700876 0.0104402688493973 0.0018062694339333 +Sphingolipid pathway 5 8 2.061808885079134 0.0392259348282419 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.0006569512931241 0.0049155620827658 5.34886142038437e-05 0.0017956484300789 0.0005081510641661 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a94ea5eb87495951011391b898f4c7c903a7548b --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 602, + "title": "Average number of proteins per term", + "value": 10.6578073089701 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b03996702624fcf586eeb54e40cf7101be23272b --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e2e7a79ad4fb8861e346d06656b5de37cec12442 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,186 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycosaminoglycan degradation 0.9006497632600902 2.447075314875302 0.0144020740564194 0.999838835974505 1.0 6 P54802,P15586,P16278 3 +Degradation pathway of sphingolipids including diseases 0.8806568191669346 2.3668431808064576 0.0179405327739683 0.9999815095458904 1.0 6 P06280,P17900,P16278,P06865 4 +Sphingolipid metabolism in senescence 0.7744762456750035 2.0949415182319857 0.0361761915123384 0.999999999767413 1.0 12 O15269,Q96G23,P16278,Q13510,P04062,Q06136 6 +Sphingolipid metabolism overview 0.8019664565960146 2.0655629024669335 0.0388697703378642 0.9999999999568574 1.0 7 Q06136,Q96G23,O95470,Q13510 4 +Sphingolipid metabolism integrated pathway 0.8019664565960146 2.0655629024669335 0.0388697703378642 0.9999999999568574 1.0 7 Q06136,Q96G23,O95470,Q13510 4 +Sphingolipid pathway 0.7953117738124196 2.061808885079134 0.0392259348282419 0.9999999999654852 1.0 8 Q96G23,Q13510,P04062,Q06136,O95470 5 +Cannabinoid receptor signaling 0.8533419908781867 1.944134146852326 0.0518792764468118 0.9999999999999882 1.0 4 Q16539,Q8NCG7 2 +Proteoglycan biosynthesis 0.7756167723248494 1.9325054248528628 0.0532971531285415 0.9999999999999952 1.0 6 Q8WVQ1,Q8TB61,Q8NCH0,Q93063 4 +Ferroptosis 0.5871242854444739 1.9269432618678184 0.0539867012423771 0.9999999999999968 1.0 26 Q9NZ45,Q9UKU0,P45880,Q9Y277,P37268,P09601,P02792 7 +Mitochondrial complex i assembly model oxphos system 0.5464647836408124 1.846301448817243 0.0648484475106443 1.0 1.0 28 O75380,O43676,Q8N183,Q9P0J0,O96000,O95168,Q9BU61,O95182,Q9Y6M9,Q8TB37,Q96CU9,O75306 12 +Vitamin a and carotenoid metabolism 0.8226989813475922 1.8180849528382184 0.069051149456246 1.0 1.0 4 Q8WTV0 1 +Cytosine methylation 0.7859097319430433 1.814121157170297 0.069659074958869 1.0 1.0 5 P48735 1 +Neuroinflammation 0.8138762993586256 1.7815601906704834 0.0748209811559132 1.0 1.0 4 P00403 1 +Nad biosynthetic pathways 0.765193824480367 1.7266841568381914 0.08422440252675 1.0 1.0 5 P43490 1 +Proteasome degradation 0.4845215604124709 1.682441821732731 0.0924831974234428 1.0 1.0 42 P62333,O75832,P04439,P28070,P25787,P28074,O00231,Q9UL46,P10321,P49720,P01889,P28072,P61289,P60900,P49721,P20618,Q99436 17 +Allograft rejection 0.6964584468292196 1.6477081071127522 0.0994125836183354 1.0 1.0 9 P04439,P10321,P01889,P42224,P08183 5 +Sarscov2 and covid19 pathway 0.7745098054851659 1.6174626134437244 0.1057784595760857 1.0 1.0 4 O14786,Q8WTV0 2 +S1p receptor signal transduction 0.6945598197272811 1.5993410518809992 0.1097448426275207 1.0 1.0 7 Q13510 1 +Il10 antiinflammatory signaling pathway 0.7464437121272072 1.4995328547531583 0.1337354519975164 1.0 1.0 4 P09601 1 +Metapathway biotransformation phase i and ii 0.5656367373116131 1.4857381886833023 0.1373483852725268 1.0 1.0 22 Q6UW02,O15217,Q8NCH0,Q86UY6 4 +Glutathione metabolism 0.7010363454511778 1.4523830543774738 0.1463951254194055 1.0 1.0 5 O75874,P11413 2 +Cholesterol biosynthesis with skeletal dysplasias 0.6517042376599809 1.3948283322788002 0.1630676129698454 1.0 1.0 6 Q16850,Q15392 2 +Rala downstream regulated genes 0.6467323843639933 1.3728200186726984 0.1698083057854342 1.0 1.0 6 P11233,Q8IYI6 2 +Nad metabolism 0.8864904033081317 1.3570533116725405 0.1747642717764592 1.0 1.0 3 P43490 1 +Ketogenesis and ketolysis 0.642126435035061 1.3524120299966174 0.1762435431386921 1.0 1.0 6 O43772,P23786 2 +Metabolism of spingolipids in er and golgi apparatus 0.8803482303849486 1.3336129359719702 0.1823307412474144 1.0 1.0 3 Q06136 1 +Statin inhibition of cholesterol production 0.6608530387342616 1.278735483288657 0.2009902199240159 1.0 1.0 5 P04035,P37268,Q8WTV0 3 +1q211 copy number variation syndrome 0.6003094324298637 1.1886993654159317 0.2345579904290167 1.0 1.0 8 Q9Y624,Q9NPH0 2 +Oxidation by cytochrome p450 0.6367112287363415 1.174205826566786 0.2403125928002558 1.0 1.0 5 Q6UW02,O43169 2 +Endothelin pathways 0.5873295983619704 1.1178510752199402 0.2636306034013009 1.0 1.0 7 P42892 1 +Hijack of ubiquitination by sarscov2 0.6161231780096048 1.0852119265408944 0.2778278030981442 1.0 1.0 5 Q8TBC4,Q15369,Q15370 3 +7oxoc and 7betahc pathways 0.5602558236590943 1.0307268329743424 0.3026689378844993 1.0 1.0 10 O14975,P61916,O15118 3 +Irinotecan pathway 0.954769230769231 1.0125197837775135 0.3112895922694325 1.0 1.0 2 O15118 1 +Familial partial lipodystrophy fpld 0.5608201375194178 1.0077128984518304 0.3135923110160006 1.0 1.0 8 O60725 1 +Alzheimers disease and mirna effects 0.4715411727492348 1.0063347192374603 0.3142545845538538 1.0 1.0 80 P28070,P21796,Q9NSK0,P05067,Q13509,P45880,Q9Y277,P28072,P0DP25,Q92542,Q96IX5,P60900,P49721,P20618 14 +Prostaglandin and leukotriene metabolism in senescence 0.7933332880838541 1.0045259545789749 0.3151251674211841 1.0 1.0 3 P09960 1 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.5423404323821307 0.9990717821577184 0.3177599194296614 1.0 1.0 13 P43490 1 +Influence of laminopathies on wnt signaling 0.5467567343858575 0.9823377709492472 0.3259334724611242 1.0 1.0 11 O60725 1 +Adipogenesis 0.5233664227251438 0.9780924917511375 0.3280285809877585 1.0 1.0 16 O75844,P43490 2 +Inclusion body myositis 0.9443076923076896 0.976932267023912 0.3286026860498867 1.0 1.0 2 P05067 1 +Nonalcoholic fatty liver disease 0.4143000395155543 0.975218317624126 0.3294519777689548 1.0 1.0 50 P14406,O75380,P00403,O43676,Q9UDW1,O95168,O95182,O75306 8 +Aryl hydrocarbon receptor pathway wp2586 0.5524068347605555 0.969302836597551 0.3323941144215634 1.0 1.0 8 P07900,P06400,Q16543,O00170 4 +Fgfr3 signaling in chondrocyte proliferation and terminal differentiation 0.617472292883332 0.9564644827892992 0.3388376201379337 1.0 1.0 4 Q16539 1 +Alzheimers disease 0.4613750317800604 0.9388862087971042 0.3477891706774056 1.0 1.0 79 P28070,P21796,Q9NSK0,P05067,Q13509,P45880,Q9Y277,P28072,P0DP25,Q92542,P60900,P49721,P20618 13 +Photodynamic therapyinduced ap1 survival signaling 0.5473297638883294 0.9377964709988844 0.3483490150284629 1.0 1.0 7 Q16539,P49327,P06400 3 +Estrogen receptor pathway 0.7700665367460764 0.9184415464475552 0.3583877481444073 1.0 1.0 3 Q9HCL2 1 +Glycogen synthesis and degradation 0.494170991941759 0.9179033356329676 0.3586694751852206 1.0 1.0 19 P35573,P63151,Q15257,P30154,P46020,P52789,P0DP25 7 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.5693931620181568 0.8850752230981266 0.3761160616727859 1.0 1.0 5 P09601 1 +Oxidative stress response 0.5681280697992045 0.8797169140145846 0.3790126842433419 1.0 1.0 5 P09601 1 +Cellular proteostasis 0.535259334525756 0.8784563432872853 0.3796961194378851 1.0 1.0 6 Q9UHV9,Q9NQP4,P61758 3 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.5613824809302607 0.8512191533779484 0.3946476250678463 1.0 1.0 5 Q15118 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.5211758601007357 0.8470135106695867 0.3969875908229041 1.0 1.0 10 P54619,O00459,P49841,P54646,Q05086,P21359 6 +Mitochondrial complex iv assembly 0.5211177674451676 0.8467427594546811 0.3971385195518606 1.0 1.0 10 P14406 1 +Monoamine transport 0.9043076923076878 0.8432007151323201 0.399116198546289 1.0 1.0 2 O15127 1 +Oxidative damage response 0.7484410122666353 0.8396725243547402 0.4010920233145205 1.0 1.0 3 O95429 1 +Il7 signaling pathway 0.5569651894042784 0.8326291251390305 0.4050539277249574 1.0 1.0 5 P40763,O00459,P42224 3 +Translation factors 0.3682887174204491 0.7938321510129349 0.4272931528850974 1.0 1.0 37 Q9UI10,P49770,P55010,Q05639,O15372,O75821,P23588,O00303,Q15056,O75153,P56537 11 +Genes related to primary cilium development based on crispr 0.487184372201295 0.7879945455313065 0.4306998963723125 1.0 1.0 16 Q9Y366,Q9Y496,Q10713,Q9C0F1,Q9H0F7,Q96EX3 6 +Nrf2 pathway 0.4508015803202854 0.7858433097836902 0.4319592899504818 1.0 1.0 22 O15217,P09601 2 +Cerebral organic acidurias including diseases 0.5447532017176722 0.7815676431811991 0.4344687089126862 1.0 1.0 5 P48735 1 +Serotonin htr1 group and fos pathway 0.5406400069496553 0.7644908887943391 0.4445747642311435 1.0 1.0 5 Q16539 1 +Progeriaassociated lipodystrophy 0.498962530126487 0.7442587329807674 0.4567199618102524 1.0 1.0 10 O60725 1 +Purinergic signaling 0.5653224419075251 0.7441997531404865 0.4567556373666503 1.0 1.0 4 P63096,Q96RD7 2 +Eicosanoid synthesis 0.8713846153846017 0.7366880989848712 0.4613120457748025 1.0 1.0 2 P09960 1 +Methionine de novo and salvage pathway 0.4980726546286286 0.7314749353256307 0.4644891087839919 1.0 1.0 9 P19623,Q13126 2 +Il9 signaling pathway 0.5322104338394631 0.7297084885861513 0.4655683913169075 1.0 1.0 5 P42224 1 +Nucleotide metabolism 0.4895459967590476 0.7238317995237314 0.4691690041629639 1.0 1.0 12 P19623,P31350 2 +Interferon type i signaling pathways 0.4789364103434417 0.7230936960048018 0.4696223220184419 1.0 1.0 15 O00459,P63244,P46108,P42224,P46109,Q16539 6 +Zinc homeostasis 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +P53 transcriptional gene network 0.4931825747448079 0.709548536417142 0.4779841428988076 1.0 1.0 9 Q9NQ88,P04066 2 +Target of rapamycin tor signaling 0.4916683079247178 0.7027804006781009 0.4821926132315359 1.0 1.0 9 P04035 1 +Apoptosis modulation by hsp70 0.5510948909618005 0.688167697094599 0.4913471834876897 1.0 1.0 4 P49327,P42575 2 +Electron transport chain oxphos system in mitochondria 0.3800305526154467 0.680007910451897 0.4964994521346777 1.0 1.0 51 P14406,O75380,P00403,O43676,Q9UDW1,O75964,O95168,O95182,Q9Y6M9,O75306 10 +Epo receptor signaling 0.4782819562867004 0.6339461955340812 0.5261159362628782 1.0 1.0 6 Q15118 1 +Vitamin d receptor pathway 0.4503078638911745 0.6208775392723913 0.5346802004445173 1.0 1.0 17 P04080,P08183,P49427 3 +Camkk2 pathway 0.4694337770182883 0.61092710680998 0.5412478385097428 1.0 1.0 10 P09601 1 +Autophagy 0.4711864406779724 0.605397600620307 0.5449148449129537 1.0 1.0 7 Q9NT62,Q7Z3C6,Q9Y4P8,P54619,P54646,P42345 6 +Kennedy pathway from sphingolipids 0.4998304390758836 0.5993669062023403 0.5489282404761417 1.0 1.0 5 O95470 1 +Spinal cord injury 0.4439217494772236 0.588171978071644 0.5564168641204148 1.0 1.0 17 P11802,P06400,P04083,O94813,P14174,Q08722 6 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4661121380160207 0.5836624267576271 0.5594474509336902 1.0 1.0 6 P18206,Q07157,P12814,P19174,P06756 5 +G1 to s cell cycle control 0.3879646215355487 0.5818671280939703 0.5606561837605168 1.0 1.0 26 P11802,P49642,P33992,P56282,P06400,P33993,P14635,Q14181,P12004,Q9Y619,P06493 11 +Ciliopathies 0.4208673036839636 0.5426793123060905 0.5873506204550658 1.0 1.0 20 Q10713,Q96EX3,Q9H0F7 3 +Notch signaling 0.4556054365525525 0.5410187697222117 0.5884946454955946 1.0 1.0 6 Q04721,Q92542 2 +Familial hyperlipidemia type 4 0.8030769230769097 0.5304170298092098 0.5958228212022734 1.0 1.0 2 Q9UBV2 1 +Fluoropyrimidine activity 0.4423538671222325 0.5066412560998413 0.6124065553037836 1.0 1.0 12 Q92820,P00374,Q06203,P31350 4 +Hepatitis c and hepatocellular carcinoma 0.4445978758712915 0.499031860999683 0.6177569387132744 1.0 1.0 9 Q16539 1 +Tryptophan metabolism 0.4308760872772842 0.4883875128964329 0.625275385004622 1.0 1.0 15 Q15392,P40939 2 +Nuclear receptors metapathway 0.3573188391102884 0.4732191790485793 0.6360568160150146 1.0 1.0 53 O15217,P23786,P09601,Q9HCL2,P08183,P27105 6 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.4227356226214473 0.4649563038467548 0.6419627487164203 1.0 1.0 16 P55209,O75844,O60725 3 +Tcell receptor tcr signaling pathway 0.4188835617533215 0.4633073933994507 0.6431440470388272 1.0 1.0 17 P49327,P46108,P46109,Q16539,Q9UDY8 5 +Burn wound healing 0.4335459703933675 0.4542379063573269 0.6496576026004364 1.0 1.0 6 P31949 1 +Dna replication 0.3433882013134494 0.4462775011361152 0.6553968061608211 1.0 1.0 29 P49642,P33992,P56282,P33993,Q14181,P41440,P12004,Q9Y619,Q15054 9 +Small cell lung cancer 0.4247309638107596 0.430021319725224 0.667180132713963 1.0 1.0 12 P11802,O14920,P06400,O00459,Q00534,P31751,P63208,P06756 8 +Nephrotic syndrome 0.4200628053343332 0.4050175478754163 0.685464612258937 1.0 1.0 11 Q14108 1 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.4658251231527024 0.3818077626102932 0.7026039604796608 1.0 1.0 4 Q96KB5,P42345,P06730 3 +Osteopontin signaling 0.4658251231526994 0.381807762610284 0.7026039604796677 1.0 1.0 4 O14920,O15111,P06756 3 +Regucalcin in proximal tubule epithelial kidney cells 0.4658251231526994 0.381807762610284 0.7026039604796677 1.0 1.0 4 Q8NE86,Q13283,P42345 3 +Type ii interferon signaling ifng 0.4123547924596479 0.3751083347094726 0.7075798986641586 1.0 1.0 6 P01889,Q03518 2 +Tgfbeta receptor signaling in skeletal dysplasias 0.6001846722068365 0.3611970104457762 0.7179521768198369 1.0 1.0 3 P40763,P42224 2 +Tgfbeta receptor signaling 0.6001846722068365 0.3611970104457762 0.7179521768198369 1.0 1.0 3 P40763,P42224 2 +Modulators of tcr signaling and t cell activation 0.4069421664916099 0.3560802529157078 0.7217804652040933 1.0 1.0 12 O96000,Q9UDY8 2 +Endochondral ossification 0.433143809654438 0.355489133796433 0.7222231840074849 1.0 1.0 5 Q9Y376,P42224 2 +Endochondral ossification with skeletal dysplasias 0.433143809654438 0.355489133796433 0.7222231840074849 1.0 1.0 5 Q9Y376,P42224 2 +Thermogenesis 0.3438871388389362 0.348260968161189 0.7276442040770401 1.0 1.0 27 O43772,Q9UKU0,P23786 3 +Hepatitis b infection 0.3666458227123012 0.3362386272864363 0.7366909264816175 1.0 1.0 23 P49327,O00459,Q9Y277,Q15904,P42224,P12004,Q16539 7 +Initiation of transcription and translation elongation at the hiv1 ltr 0.3980591553137132 0.3245277920804546 0.7455384847882129 1.0 1.0 6 Q8IXH7,P18615 2 +Methylation pathways 0.5828804369437848 0.3162146724100087 0.7518395717378477 1.0 1.0 3 P31153 1 +3q29 copy number variation syndrome 0.3964326981715421 0.3142727604054621 0.7533138849501086 1.0 1.0 12 P61088,Q96EX3,P63167,O94888,Q96FJ2,P52298 6 +Map3k1 role in promoting and blocking gonadal determination 0.4194641207268306 0.3111773327850209 0.7556658140178214 1.0 1.0 5 Q9Y6R4,P28482,P35222,P49841 4 +Interactions between loxl4 and oxidative stress pathway 0.7147692307692134 0.3070925782148748 0.7587729066810307 1.0 1.0 2 Q16543 1 +Liver x receptor pathway 0.7110769230769266 0.299109782360646 0.7648562825354932 1.0 1.0 2 P49327 1 +Regulatory circuits of the stat3 signaling pathway 0.3909887344229754 0.2909032352007511 0.7711253269380514 1.0 1.0 9 Q8WTS6,Q16539 2 +Urea cycle and associated pathways 0.3886826240588539 0.2880862510511346 0.7732807167695095 1.0 1.0 13 Q9Y619 1 +Ebola virus infection in host 0.3079748509795888 0.2755570210867114 0.7828883241521889 1.0 1.0 40 P04439,P61916,Q99816,O15118,P10321,O00459,P01889,P42224,P09496,P41440,Q9P253 11 +Mitochondrial complex iii assembly 0.3849469983421488 0.2685382903568101 0.788285005379799 1.0 1.0 10 Q6DKK2,Q9UDW1 2 +Bladder cancer 0.3811069608548779 0.2630116950707915 0.7925415650145222 1.0 1.0 7 P06400,P11802 2 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3798642492569459 0.2589510764111718 0.7956729885552187 1.0 1.0 7 Q15118 1 +Mitochondrial long chain fatty acid betaoxidation 0.3798511247681644 0.2542371376401938 0.7993123612500785 1.0 1.0 13 P23786,P40939 2 +Fatty acid betaoxidation 0.3594209899840699 0.2521924435582172 0.8008923185232484 1.0 1.0 21 Q9UKU0,P23786,P40939 3 +Head and neck squamous cell carcinoma 0.3712640506106776 0.2469591953524212 0.8049398034789659 1.0 1.0 17 Q14517,P06400,P11802,Q04721 4 +B cell receptor signaling pathway 0.3653254869385982 0.2458432616858751 0.8058035665591974 1.0 1.0 19 Q16539,Q9UDY8,P46108 3 +Mirna biogenesis 0.417795566502453 0.2425446784597652 0.8083581416998855 1.0 1.0 4 Q9HAV4,Q8WYQ5,Q9UPY3 3 +Folate metabolism 0.3727289526444209 0.2313729690067468 0.8170250630721063 1.0 1.0 14 P41440,Q8WTV0 2 +Leukocyteintrinsic hippo pathway functions 0.3668556765821122 0.2234856736871876 0.8231575319293232 1.0 1.0 6 Q16539 1 +Mirna regulation of prostate cancer signaling pathways 0.3645608628659418 0.210867531512745 0.8329906405405834 1.0 1.0 7 P62993,Q8NCF5,P28482,P49841,P35222,P42345 6 +Exrna mechanism of action and biogenesis 0.5318559556786745 0.2022290843520175 0.8397376368109841 1.0 1.0 3 Q9HAV4,Q8WYQ5 2 +Striated muscle contraction pathway 0.3508934072704839 0.1774771364098522 0.8591336226500921 1.0 1.0 6 P28289,P67936,P09493,O43707,P06753 5 +Melanoma 0.3551615032497959 0.1711771352888886 0.8640844855274379 1.0 1.0 15 P06400,P11802,P0DP25,O00459 4 +Signal transduction through il1r 0.3479327022430052 0.1694056605827893 0.8654775713562541 1.0 1.0 6 Q9BQ95,Q16539,Q15750 3 +Mecp2 and associated rett syndrome 0.3359061340019244 0.1626142079038745 0.8708221996107879 1.0 1.0 22 Q03518,P67809,Q05086,P52597,P35637,P31943 6 +22q112 copy number variation syndrome 0.2809314667394246 0.1616102050756957 0.8716128204742128 1.0 1.0 34 Q96DF8,Q9NQ50,P21964,P00367,O00192,P46109,Q92973,Q9UDY8,Q9BW71 9 +Urea cycle and metabolism of amino groups 0.3484982695069373 0.1588233473531256 0.8738080537594581 1.0 1.0 8 P19623 1 +Serine metabolism 0.3427078070588815 0.155527018894904 0.8764058550957192 1.0 1.0 6 P00374 1 +Ethanol effects on histone modifications 0.3491519879737179 0.1476466814094586 0.8826216123702977 1.0 1.0 12 P41440,P04818,Q9H9T3,P00374 4 +Unfolded protein response 0.3642241379310253 0.1264660724839517 0.8993630036172511 1.0 1.0 4 P05198,P42575,Q9Y3I0 3 +Leptininsulin signaling overlap 0.6027692307692369 0.1216904422046646 0.9031441829948356 1.0 1.0 2 P40763 1 +Pentose phosphate metabolism 0.345935967025633 0.1192739915861195 0.9050582880940068 1.0 1.0 5 P11413 1 +Constitutive androstane receptor pathway 0.3273564029456249 0.117525442105728 0.9064436838609982 1.0 1.0 6 Q15257,P08183 2 +Supression of hmgb1 mediated inflammation by thbd 0.4770698676515896 0.1136275465534503 0.909533049778755 1.0 1.0 3 O14920,P09429 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.3242866294434233 0.1130426336235381 0.9099967550737572 1.0 1.0 22 P04035,Q15392,P35610,P37268,Q14739,Q16850 6 +Aryl hydrocarbon receptor pathway wp2873 0.3419760933572518 0.1114250129273223 0.9112793261130048 1.0 1.0 5 P07900,Q16543 2 +Hostpathogen interaction of human coronaviruses autophagy 0.470606340412439 0.1055055067287184 0.915974700641396 1.0 1.0 3 Q9NT62,P42345 2 +Sting pathway in kawasakilike disease and covid19 0.4675284702985575 0.1018051726121648 0.9189113198352004 1.0 1.0 3 O14920,O15111 2 +Tolllike receptor signaling pathway 0.3319833916230673 0.1005173062048211 0.9199336440550934 1.0 1.0 11 Q16539,O00459,P42224 3 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.4656817482302295 0.0996362584357138 0.9206331069727678 1.0 1.0 3 P19174,P06756 2 +Tolllike receptor signaling related to myd88 0.4656817482302288 0.099636258435713 0.9206331069727683 1.0 1.0 3 O14920,O15111 2 +Mapk and nfkb signaling pathways inhibited by yersinia yopj 0.4656817482302288 0.099636258435713 0.9206331069727683 1.0 1.0 3 O14920,O15111 2 +Pentose phosphate pathway in senescent cells 0.3350785340314144 0.0983932739429537 0.9216200153814368 1.0 1.0 5 O95336,P04637,P37837,P11413 4 +Chemokine signaling pathway 0.3171149595647587 0.0979640151410316 0.921960867639146 1.0 1.0 23 P04899,P63096,O14920,O00459,P40763,P46108,P49841,P42224,Q13153,P31751,P46109,P41240 12 +Il2 signaling pathway 0.3205631893091589 0.0946196702576642 0.9246169253265863 1.0 1.0 7 P46109 1 +Kit receptor signaling pathway 0.3309630352641595 0.0914212247288296 0.9271578974727248 1.0 1.0 15 Q16539,P46108,P46109 3 +Hostpathogen interaction of human coronaviruses interferon induction 0.3211863560194886 0.0892124085389736 0.9289131041123406 1.0 1.0 8 Q16539 1 +Sudden infant death syndrome sids susceptibility pathways 0.2936883198313809 0.0716034290672496 0.942917511081676 1.0 1.0 27 P42892,P40939 2 +Mevalonate arm of cholesterol biosynthesis pathway 0.3179381737739015 0.0699571492105506 0.944227766010489 1.0 1.0 10 P35610,P04035,P37268 3 +Fragile x syndrome 0.2765333592824433 0.0690509187475348 0.9449490888878244 1.0 1.0 40 P05067,P10644,P50570,P51648,Q9NZ01,Q15118 6 +P38 mapk signaling pathway 0.3111654461341722 0.0672440266577558 0.94638743621478 1.0 1.0 8 Q16539 1 +Vitamin b12 disorders 0.3214981048022556 0.0659712207583309 0.9474007380325824 1.0 1.0 4 Q96EY8,Q99707 2 +Congenital generalized lipodystrophy cgl 0.5350769230769339 0.0649995075064543 0.948174392380018 1.0 1.0 2 P31751 1 +Parkinsons disease pathway 0.3034033313411233 0.0515766517856215 0.9588660237484156 1.0 1.0 8 Q16539,P42575 2 +Netrinunc5b signaling pathway 0.3089407262396853 0.0499273672348385 0.9601802685947892 1.0 1.0 10 P30154 1 +Mevalonate pathway 0.3034343641855792 0.0489315715131251 0.9609738285601191 1.0 1.0 5 P04035 1 +Il4 signaling pathway 0.308126805604776 0.0481980000649068 0.9615584440540892 1.0 1.0 10 Q16539,P42224 2 +Autosomal recessive osteopetrosis pathways 0.400430901815948 0.0454815982986088 0.9637234421493712 1.0 1.0 3 O14920,P51798 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.3124743233391981 0.044160152805407 0.9647767445029648 1.0 1.0 13 P55010,O00303,O15372,O75821 4 +Photodynamic therapyinduced nfkb survival signaling 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +Canonical nfkb pathway 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +Altered glycosylation of muc1 in tumor microenvironment 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 1.0 2 O14920 1 +Folatealcohol and cancer pathway hypotheses 0.4738461538461626 0.040641945709796 0.967581343924524 1.0 1.0 2 Q99707 1 +Pdgfrbeta pathway 0.2874306839186771 0.0389157464249808 0.9689575622471018 1.0 1.0 6 P62993,P40763,P42224,P19174,P19525 5 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.4655384615384616 0.0387175429849004 0.9691155866165464 1.0 1.0 2 P40763 1 +Steroid biosynthesis 0.4443076923076922 0.0348763019313357 0.9721783774336724 1.0 1.0 2 P51659 1 +Metastatic brain tumor 0.3641120344721503 0.030693015447555 0.9755143614052612 1.0 1.0 3 Q00534,P60953 2 +Mammary gland development pathway involution stage 4 of 4 0.3640000000000004 0.0290610830282848 0.9768158739230484 1.0 1.0 2 P40763 1 +Aflatoxin b1 metabolism 0.3495384615384556 0.0287743613983188 0.9770445490510382 1.0 1.0 2 P07099 1 +Il1 signaling pathway 0.299069200747129 0.0239621203197071 0.9808828236305928 1.0 1.0 11 Q16539,O00459,Q15750,P61088 4 +Nephrogenesis 0.319120692103211 0.0218774581945424 0.9825457062263264 1.0 1.0 3 Q04721 1 +Retinoblastoma gene in cancer 0.28006552141211 0.0213968827424895 0.9829290602087584 1.0 1.0 47 P11802,P00374,P27707,P56282,P06400,P33993,P04818,P14635,P06493,P16949,P12004,Q9Y619,P26583,P31350,Q15054 15 +Alpha 6 beta 4 signaling pathway 0.2861430642832754 0.0209536020072283 0.9832826677745372 1.0 1.0 8 Q16539 1 +Nanoparticle triggered autophagic cell death 0.308402585410901 0.0207816510643511 0.9834198349084022 1.0 1.0 3 Q9NT62,Q9Y371 2 +Canonical and noncanonical notch signaling 0.3040935672514669 0.0204171691283278 0.9837105877212944 1.0 1.0 3 O15111,Q04721 2 +Robo4 and vegf signaling pathways crosstalk 0.2483841181902181 0.0181868358331743 0.9854898043843928 1.0 1.0 3 P63000,O94813 2 +Vitamin dsensitive calcium signaling in depression 0.2718344840825251 0.0154501267402235 0.9876730728329136 1.0 1.0 5 P11413 1 +Rac1pak1p38mmp2 pathway 0.3003889919827072 0.0067799517995975 0.9945904225804924 1.0 1.0 17 P46108 1 +Biomarkers for pyrimidine metabolism disorders 0.2698419634204269 0.005264300554425 0.9957997152645246 1.0 1.0 7 P31350 1 +Development of ureteric collection system 0.2545875210335957 0.0030061814269201 0.9976014178652036 1.0 1.0 5 Q9Y6N7 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a5092625b08cdb52a26752b047833f8649d2cb6a --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amplification and expansion of oncogenic pathways as metastatic traits", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANXA1", "ANXA2", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARL2", "ARL3", "ARL5B", "ARL6", "ARMC9", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GAT3", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BLM", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD1", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "C1QBP", "C6orf89", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP2", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CIT", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMPK1", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRAT", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUX1", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DBI", "DCAF1", "DCAF7", "DCK", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAT1", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FOXRED1", "FSCN1", "FTL", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNS", "GALNT1", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID4", "GID8", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF15", "KIF1B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC4", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSS", "LTA4H", "LZTFL1", "MACF1", "MALT1", "MANF", "MAP1B", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "METTL3", "MFAP1", "MFGE8", "MFN2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "MYO9B", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOA4", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "OSBPL3", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICK1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA2", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PURA", "PUS1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QKI", "QPRT", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD4", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STK3", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX16", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TALDO1", "TAOK1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRIP4", "TRRAP", "TSG101", "TSPO", "TTC19", "TTC26", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2J1", "UBE2L3", "UBE2N", "UBE3A", "UBR2", "UBR5", "UBTF", "UBXN7", "UCHL5", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNG", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDCP", "WDHD1", "WDR1", "WDR26", "WDR34", "WDR5", "WFS1", "WIPI2", "WNK1", "WRN", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACP6", "ACSL6", "ACTN1", "ACTN4", "AGL", "AIP", "AKT2", "ALDH3A2", "ANXA1", "APP", "ARL6", "ARVCF", "ASAH1", "ATG3", "ATG9A", "ATP5L", "ATP6AP1", "BAG4", "CAB39", "CALM3", "CANT1", "CASP2", "CCNB1", "CD47", "CDC34", "CDC37", "CDC42", "CDK1", "CDK4", "CDK6", "CEP44", "CERS2", "CHST14", "CHUK", "CISD1", "CLCN7", "CLTA", "CLUH", "COMT", "COX2", "COX7A2", "CPT2", "CRK", "CRKL", "CSK", "CSTB", "CTNNB1", "CYB5B", "CYP20A1", "CYP51A1", "DAGLB", "DCK", "DGCR8", "DHCR24", "DHFR", "DICER1", "DNM2", "DYNLL1", "DYNLL2", "ECE1", "ECSIT", "EEF1A2", "EIF2AK2", "EIF2B2", "EIF2B4", "EIF2S1", "EIF3F", "EIF3G", "EIF3H", "EIF4B", "EIF4E", "EIF4H", "EIF5", "EIF6", "ELOB", "ELOC", "ELP3", "EPHX1", "ESS2", "EXOC8", "EXT2", "F11R", "FASN", "FAT1", "FDFT1", "FOXRED1", "FTL", "FUCA1", "FUS", "G3BP1", "G6PD", "GBA", "GGH", "GLA", "GLB1", "GLUD1", "GM2A", "GNAI1", "GNAI2", "GNS", "GPAM", "GRB2", "GSK3B", "GSTA4", "HADHA", "HEXA", "HIRIP3", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMGB1", "HMGB2", "HMGCR", "HMOX1", "HNRNPF", "HNRNPH1", "HSD17B4", "HSP90AA1", "ICMT", "IDH1", "IDH2", "IFT52", "IKBKB", "ITGAV", "KDSR", "KIF3A", "KLC4", "LBR", "LTA4H", "MALT1", "MAP3K4", "MAPK1", "MAPK14", "MAT2A", "MCM5", "MCM7", "MCU", "MIF", "MMAB", "MRPL40", "MTAP", "MTOR", "MTR", "NAA40", "NAGLU", "NAMPT", "NAP1L1", "NCBP2", "NCSTN", "NDUFA13", "NDUFA7", "NDUFAF2", "NDUFAF3", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NDUFS6", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NOTCH2", "NPC1", "NPC2", "NRP1", "NUBPL", "PAK1", "PANX1", "PBK", "PCNA", "PDK1", "PFDN2", "PFDN4", "PGLS", "PHKA1", "PIK3R2", "PLCG1", "PMPCA", "POLA2", "POLD3", "POLE2", "PPAT", "PPP2R1B", "PPP2R2A", "PRIM1", "PRKAA2", "PRKAG1", "PRKAR1A", "PSMA2", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC6", "PSMD10", "PSMD11", "PSME2", "PSME3", "PTPA", "RAC1", "RACK1", "RALA", "RB1", "ROBO1", "RRM2", "RTCB", "S100A11", "SCAMP2", "SCARB1", "SCARB2", "SEL1L", "SETD7", "SGPL1", "SH3GLB1", "SKP1", "SLC19A1", "SLC25A15", "SLC25A20", "SLC27A2", "SLC30A5", "SLC35B2", "SLIT2", "SOAT1", "SPTLC1", "SRM", "STAT1", "STAT3", "STMN1", "STOM", "TAB1", "TALDO1", "TAP1", "TECR", "TIGAR", "TJP1", "TMOD1", "TNPO1", "TP53", "TPM1", "TPM3", "TPM4", "TSG101", "TTC19", "TUBB3", "TYMS", "UBA3", "UBE2N", "UBE3A", "UBXN7", "UQCR10", "USMG5", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS18", "WDR34", "WIPI2", "XPO5", "YBX1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e77640fd2d486c182953c84dda188669948fded5 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "golgi"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6b0723a6b843b90443a67b132b395a9f6c9e5b46 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e565bf73e723bd01fae676377da3739ce9cfa02fb86f2d6c975d3790a48d538 +size 141081 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..218a6a10322ff41b2a92592ed43687f175aeb865 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e0c467f4fe532f3209b91acc5d46c457c8b535271d2320190fd55a43be7316e3 +size 71624 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5d91e824b42e6db88f8ab206fd51a7bc19b1411a --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 97.05882352941177 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bf5296eabf8762b1fdda72d81914cfcdfc25344a --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4de274d90347411623e54e6581184ee1fa4fb040 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mitochondria 0.6560852124032508 1.5079665952497314 0.1315630767485647 0.9091027465975986 1.0 11 P21796 1 +golgi 0.3989840916236972 0.6349120991716216 0.5254857455277349 0.999996865000508 1.0 65 Q9H0U4,Q15907,Q8NBN3,Q8N6T3,Q92538,Q15437,Q8TAD4,Q15904,Q9Y487,Q8IXU6,O15127,Q9Y3E0,O15126,Q8IZA0,Q96A49,Q13190,Q5VW38 17 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5c3ea9958c05335d6fa99a20603df21c33751f07 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", 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file mode 100644 index 0000000000000000000000000000000000000000..2db40500b0ab9e38dbdae0af7c63a80eac50c87f --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +membrane trafficking regulatory protein 8 22 2.531864322419159 0.0113457883373868 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0004289450550452 0.0266825716175236 0.0001546792596973 4.636915257467212e-06 0.0002097833953999 +metalloprotease 13 28 2.4385845129317065 0.014744910436397 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.0032183297593839 1.0 0.0965403494275516 0.0003166514040067 1.3828829712021432e-06 +glycosidase 2 5 2.238396080832645 0.0251952373889858 2.349514563106796 4.621359223300971 -0.2307336370526829 0.2597902373581335 1.0699672244692364 0.6012366681705257 1.6034021241460206 0.2766391836749902 0.0002109803919781 1.0 1.0 0.0004683577123997 0.00351763180786 +protein modifying enzyme 7 27 2.0152790971470385 0.0438754138340087 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.0226867864895969 0.0315268496209905 0.0186371594327644 0.0133513277547448 0.0069005748974321 +transporter 11 56 2.0121685097128497 0.0442021767804936 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 1.0960687324197555e-05 0.1084777994315797 0.0001363362205479 2.730098665052329e-05 5.118639683450527e-05 +phospholipase 1 7 1.9767818647635065 0.0480662924765069 2.0266990291262137 7.405339805825243 0.812358854363279 0.2972812642592555 1.2910317153343125 1.5290934655146406 1.1524828353366978 0.2736190413418742 0.1070428504887252 0.134742527043449 0.2540772386550496 0.1658780833937837 0.435660416614262 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9dcfa6a4b6e9cc850dee34fd736e55fbe61a9706 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 158, + "title": "Average number of proteins per term", + "value": 14.0 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1119e9a11833db5c1790996d89a7b7ad645086f9 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2cd9ad2bd4b2a4d42c05bf8b6c7ec8bfeb04e893 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,56 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +membrane trafficking regulatory protein 0.7467259387939928 2.531864322419159 0.0113457883373868 0.8351767455027505 0.5810272940323916 22 P24390,O43760,O43731,Q14108,Q15833,O00560,Q8WTV0,P13473 8 +metalloprotease 0.6331764730016841 2.4385845129317065 0.014744910436397 0.9043483326598604 0.5810272940323916 28 Q10713,Q6P179,Q99797,P55786,P42892,P22695,P53582,Q9BYT8,O75844,Q9NZ08,Q9UIQ6,Q96KP4,O43847 13 +glycosidase 0.8888594202899729 2.238396080832645 0.0251952373889858 0.9822586161679848 0.5810272940323916 5 Q9BTY2,P04066 2 +protein modifying enzyme 0.5859165220049258 2.0152790971470385 0.0438754138340087 0.9991657642802668 0.5810272940323916 27 Q9UMR5,O75718,O15460,P50897,O60725,O00462,Q9Y570 7 +transporter 0.5536884597165863 2.0121685097128497 0.0442021767804936 0.9992096237854402 0.5810272940323916 56 Q9C0E2,Q9Y619,Q96P70,Q9HD45,Q00169,O95373,Q567V2,Q99595,Q9H2D1,O43772,Q9Y584 11 +phospholipase 0.7811283144322271 1.9767818647635065 0.0480662924765069 0.999583265524349 0.5810272940323916 7 Q8NHP8 1 +serine protease 0.708136592554903 1.9447886117072812 0.0518004253238078 0.999776044632366 0.5810272940323916 16 P10619,Q9H3G5,Q9HB40,P42785,O14773 5 +oxygenase 0.7496676840467582 1.821972546606622 0.0684591513385139 0.9999863886628664 0.619106783309731 6 P30519,Q6UW02,P09601 3 +transmembrane signal receptor 0.7172850971829406 1.6823745582177425 0.0924962316401427 0.9999997811971064 0.7307202299571277 6 O15173,Q15375 2 +protease inhibitor 0.6923197750192489 1.6288279239193832 0.1033494515877944 0.9999999673059656 0.7775815881367389 9 P04080,Q92530,P05067 3 +galactosidase 0.9495229301323488 1.597618315919688 0.1101279476535341 0.9999999901427528 0.7787576296332281 3 P06280,Q8IW92 2 +mitochondrial carrier protein 0.6731128805683548 1.540851058829264 0.1233530394264077 0.9999999990746468 0.7787576296332281 9 Q9BSK2,Q70HW3 2 +voltage-gated ion channel 0.9076638965835648 1.4379046491687717 0.1504611103996798 0.9999999999935292 0.7787576296332281 3 P45880,P21796 2 +esterase 0.6471507806208504 1.421097589237288 0.1552883907561431 0.99999999999737 0.7787576296332281 9 Q9NUJ1,Q969T7 2 +G-protein 0.6474911940932836 1.3891934571815294 0.164773930750542 0.9999999999995584 0.7787576296332281 7 Q9NTK5 1 +oxidase 0.6111871932464521 1.373126903424574 0.1697128986982816 0.999999999999827 0.7787576296332281 14 P14406,Q6QHF9 2 +GTPase-activating protein 0.6169842404790492 1.372044397991357 0.1700496169341401 0.9999999999998376 0.7787576296332281 13 Q8N6T3,Q86VI3,Q8TC07,Q9H0H5 4 +oxidoreductase 0.4439759745639859 1.2679410482979885 0.2048190037631267 0.9999999999999998 0.7787576296332281 47 O75380,P00403,O43676,O95168,Q8N0U8,Q8N4Q0,O95182,O43169,O75306 9 +ATP-binding cassette (ABC) transporter 0.6140837657623139 1.2675213971509598 0.2049689176720921 0.9999999999999998 0.7787576296332281 9 P33527,Q9NUT2,P08183,Q03518 4 +primary active transporter 0.5255663864144151 1.241826775523709 0.2143004814234914 1.0 0.7787576296332281 22 Q9NS69,O60888 2 +secondary carrier transporter 0.5661724766485097 1.2415831755275395 0.2143903924462851 1.0 0.7787576296332281 17 O00400,Q9UBX3,Q96H78,Q15043,Q8TB61,O14975 6 +major histocompatibility complex protein 0.8519544475223157 1.2254556297058945 0.22040359797372 1.0 0.7787576296332281 3 P01889,P10321 2 +tubulin 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.7787576296332281 5 P04350,Q9BUF5,Q13509 3 +G-protein modulator 0.6731554470853963 1.1898990780743497 0.2340860608825081 1.0 0.7844836555823425 4 P52565 1 +SNARE protein 0.582747148787743 1.1372614973114292 0.2554289853255287 1.0 0.7875259558541624 10 O60499,Q9P2W9,Q13190,Q9UNK0 4 +G-protein coupled receptor 0.9784615384615372 1.0938491192636686 0.2740211571899404 1.0 0.8017656080742703 2 Q5VW38 1 +kinase modulator 0.5780055054362518 1.0673564530178166 0.2858109048275248 1.0 0.8171413935218109 6 P10644,O00459 2 +transfer/carrier protein 0.5396636765171982 0.9656401626924714 0.3342242709833829 1.0 0.9264462248311316 12 P17900,O15127,Q9Y5M8 3 +transferase 0.3943725363860795 0.8995056495922332 0.3683833879189357 1.0 0.9454400937157308 30 O15217,Q8NCH0,P43490,P19623 4 +calmodulin-related 0.5040223312815606 0.850709630638627 0.3949306720584697 1.0 0.9454400937157308 15 P80303,Q14257,P30626,P0DP25,Q02818,O43852 6 +heterotrimeric G-protein 0.5036968576709651 0.7414785039310147 0.4584033607486808 1.0 0.9513855913348248 6 P04899,P63096,Q8NHH9,Q14344,P08754 5 +reductase 0.3729579402652644 0.7328499697976069 0.4636499400808955 1.0 0.9513855913348248 30 Q9H7Z7,P35270,P04035,P00374,O95881,Q9UDW1,Q15392,Q06136,P31350 9 +protease 0.3614580268232799 0.7064381816019846 0.4799156835633882 1.0 0.9527258897892856 39 P28070,P20618,P28072,P60900,P49721,Q9BT78 6 +damaged DNA-binding protein 0.6862452671067512 0.6228356337519623 0.5333925392590335 1.0 0.9799537349177592 3 P54725 1 +cysteine protease 0.3829857248873524 0.6029368549930263 0.5465506970807401 1.0 0.9841065909378528 27 Q96FW1,Q13510,P51784,P53634,Q9Y4P1,Q92820,Q9UDY8 7 +translation factor 0.4931772469909062 0.5733587920059672 0.5664017856349273 1.0 0.9897126796565252 5 P51114,Q05639,P51116 3 +kinase activator 0.6668706266816083 0.5592681022149314 0.5759787612881728 1.0 0.9897126796565252 3 P46020 1 +small GTPase 0.4525427192408693 0.5435876400495864 0.5867252670730936 1.0 0.9911147258645858 11 P11233,Q3YEC7,P61225 3 +phosphatase 0.4039922562504212 0.429320552245878 0.6676899621382335 1.0 1.0 19 Q9C0I1,P11117,P29218,Q9NPH0,Q9H773 5 +acyltransferase 0.3907395408802674 0.3846495631065083 0.7004970680386844 1.0 1.0 20 Q8NCC3,P49356,P23786,P35610,Q9HCL2 5 +DNA-directed DNA polymerase 0.4147341950025363 0.3792285581339278 0.7045181463208279 1.0 1.0 8 P56282 1 +phosphatase modulator 0.4062856988908017 0.3533372712598643 0.7238356067917093 1.0 1.0 6 P30154,P30153 2 +ATP synthase 0.3724895342069468 0.3396696367802954 0.7341053299545566 1.0 1.0 22 Q9Y487,O75964,Q15904,Q96IX5,Q5MIZ7,Q93050 6 +lyase 0.3989943714316245 0.335795188459923 0.7370253187692621 1.0 1.0 14 Q9UHG3 1 +membrane traffic protein 0.3530485773011653 0.2909716459777731 0.7710730049491274 1.0 1.0 65 Q9UPT5,P43307,Q10567,P11717,O43493,O60313,Q9UQN3,Q9H4M9,Q92734,P50570,Q8N2H4,P20645,Q9NX40,Q709C8,Q9H223,A6NIH7 16 +calcium-binding protein 0.4099788468673957 0.2818686820521908 0.7780442043425002 1.0 1.0 5 P50995,P04083 2 +Hsp90 family chaperone 0.4152658367644439 0.2360783280961267 0.8133718903580061 1.0 1.0 4 P08238 1 +nucleic acid metabolism protein 0.3898064571799301 0.2237362972796547 0.8229625006621071 1.0 1.0 5 Q96FV9 1 +non-motor microtubule binding protein 0.3476687348358304 0.2163199984620346 0.8287383215693074 1.0 1.0 22 Q15691,Q9UH99,Q9BZD4,Q9BSJ2,Q66K74,Q9UN37,Q3KQU3,Q15555,P13693,Q4ZIN3 10 +extracellular matrix protein 0.3991241109945085 0.1970555693943672 0.8437840521208779 1.0 1.0 4 O43290 1 +acetyltransferase 0.3623502935206228 0.190742473962297 0.8487273601562659 1.0 1.0 11 Q14CX7,Q5VZE5,Q96N66,Q9BXJ9,P41227 5 +cyclase 0.6501538461538495 0.1855460726761305 0.8528007468052321 1.0 1.0 2 P48449 1 +amino acid transporter 0.3912228864116217 0.1794003265279312 0.857623375014015 1.0 1.0 4 O14925 1 +translation initiation factor 0.2871003417269373 0.0708962264448541 0.9434803466809484 1.0 1.0 46 Q9UJA5,Q9Y262,Q9UI10,P49770,P55010,O15372,Q92905,P56537,P23588,O00303,Q15056,O75153,O75821 13 +integrin 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..762a726273f2e692facf078cd64223d122e950ee --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "storage protein", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD6", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANKS1A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APIP", "APLP2", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARIH1", "ARL1", "ARL5B", "ARL6", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATL2", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BCAP31", "BCAS2", "BCKDHA", "BCLAF1", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCDC94", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC16", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CEP170", "CEP250", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIT", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT4", "CNOT7", "CNP", "COA3", "COG4", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBT", "DCAKD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FAT1", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GID8", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOSR1", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDAH", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MALT1", "MAN1A2", "MANBA", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "MFAP1", "MFGE8", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA4", "NCOA5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NF1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PAFAH1B3", "PAIP1", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAOX", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTCD1", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD18", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC39A14", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC7A11", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG9", "SPCS2", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TARBP1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM259", "TMEM38B", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TP53RK", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRIM21", "TRIM26", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TST", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR2", "UBR4", "UBR5", "UBTF", "UCHL5", "UFL1", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNG", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS53", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR82", "WIZ", "WNK1", "WRN", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", 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0000000000000000000000000000000000000000..33a40069cde0bc3b3b6ac2e4ab7fabf164f8ad33 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce0e2c49abb92ffa8e5612df10841a7a9728d04396c960af92c468deaf44d8c9 +size 202881 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5290f1635e1ba7d3ab218ff7ffbcab8542e66011 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 6 28 2.668372118719072 0.0076219787939038 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0036052848215439 0.4014813083941581 0.003645938876645 0.014982846631896 0.0748588950516411 +SLC25 family of mitochondrial transporters 7 24 2.3406506941693817 0.0192501680679446 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 5.560848899895417e-05 0.0135379522122687 2.656375344257793e-05 2.3646312886132144e-06 5.453694042240354e-05 +Mitochondrial amino acid transporter subfamily 2 6 2.3404664049760178 0.0192596710696582 1.75 5.106796116504855 1.5314439851709 0.1644824524943633 1.357512359363716 0.7195281808878056 0.8276270779181836 0.2049815877367878 0.0003329397892747 1.0 0.0025156479029566 0.0007358710981923 0.00542484368483 +Metalloprotease 16 40 2.318026106089793 0.0204479022957988 10.080097087378642 37.81310679611651 1.0846602244748076 0.3802793741361127 4.2814674000125414 2.184793664748831 0.9789887795730944 0.3416347995760264 0.0115198261969022 1.0 0.1579906452537346 0.0019675889741868 9.701072169351205e-06 +SLC superfamily of solute carriers 18 50 2.149970662660327 0.0315575354413764 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.0538542088458706 0.2177059049323894 0.0319499068250687 0.0050289456262941 0.0014625688035412 +Membrane trafficking regulatory protein 6 23 2.1284604773530504 0.0332989234833731 4.560679611650485 20.218446601941743 0.5159227056829229 0.4386866271320015 2.6094874555832708 2.7661001804550924 1.1256129588723178 0.3307884378613797 0.0103585479452413 0.0204708743585679 0.0099655953739765 0.0001129805864544 0.0065667902134515 +Mitochondrial nucleotide transporter subfamily 3 11 2.0902112865047084 0.0365988241229582 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0024567571854954 0.0022827689145391 0.0003712110430798 0.0003832983840783 0.0050247198439474 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..93f71ec9455ea834a323c730d675c679c47551d3 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 2053, + "title": "Average number of proteins per term", + "value": 3.13346322454944 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..73de3a24ffa9025809aa17fd3914d8ca44d4574f --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a5a7c673318b1c8053348fe8ce261275900c1906 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,66 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6683126414560113 2.6683721187190717 0.0076219787939038 0.999999849282904 0.3167870113320186 28 Q567V2,Q14108,Q9UQB8,P57105,Q8WTV0,A6NIH7 6 +SLC25 family of mitochondrial transporters 0.6829024793083565 2.3406506941693817 0.0192501680679446 1.0 0.3167870113320186 24 Q9BSK2,Q70HW3,O43772,Q96H78,Q9UBX3,Q9H2D1,Q9Y619 7 +Mitochondrial amino acid transporter subfamily 0.8741262066901214 2.3404664049760178 0.0192596710696582 1.0 0.3167870113320186 6 Q9Y619,Q96H78 2 +Metalloprotease 0.5604442240826802 2.318026106089793 0.0204479022957988 1.0 0.3167870113320186 40 P31930,Q10713,Q6P179,Q99797,P55786,P42892,P22695,Q7Z2K6,P53582,Q9BYT8,O75844,Q9NZ08,O00303,Q9UIQ6,Q96KP4,O43847 16 +SLC superfamily of solute carriers 0.5594116293194717 2.149970662660327 0.0315575354413764 1.0 0.3167870113320186 50 Q9BSK2,Q9Y619,Q70HW3,Q9H2V7,O00400,Q9BQT8,Q8TB61,Q96H78,Q8TAD4,Q8IXU6,Q9UBX3,Q86VD7,Q9H2D1,Q9HC07,P41440,Q15043,O43772,O14975 18 +Membrane trafficking regulatory protein 0.6612716551422461 2.1284604773530504 0.0332989234833731 1.0 0.3167870113320186 23 P24390,O43760,O43731,Q15833,O00560,P13473 6 +Mitochondrial nucleotide transporter subfamily 0.7813064419629394 2.0902112865047084 0.0365988241229582 1.0 0.3167870113320186 11 Q9BSK2,Q9H2D1,Q70HW3 3 +Protease inhibitor 0.7482570082932116 1.908977472309035 0.0562649978330316 1.0 0.3306527265991443 10 P04080,Q92530,P05067,P27105 4 +G-protein 0.5146592114271037 1.8344543924035828 0.0665865718985927 1.0 0.3426313230528767 30 O15397,Q96P70,Q9NTK5,O60313,O95373,P50570,P11233,P61225 8 +Phosphatase inhibitor 0.7831801775215437 1.8026365635354864 0.0714453108035666 1.0 0.3483364429737184 5 Q01105,P55209 2 +Esterase 0.7029703933275139 1.760291862748327 0.0783583331598598 1.0 0.35590632295839 12 P50897,Q9UMR5,Q969T7 3 +Reductase 0.6625678793491019 1.7117959420584683 0.086934280165329 1.0 0.3678704545834368 16 Q9H7Z7,O95881,P00374,Q9UDW1,Q15392,O95168,P31350 7 +SNARE protein 0.6870747093506594 1.6048602617770975 0.1085245604880487 1.0 0.3936412061518798 9 O60499,Q9P2W9,Q13190,Q9UNK0 4 +Galactosidase 0.9495229301323488 1.597618315919688 0.1101279476535341 1.0 0.3964224071478296 3 O00462,Q8IW92 2 +Phosphatase modulator 0.6666241059247812 1.4749482687658686 0.1402264518650851 1.0 0.4324625536464089 7 Q01105,P55209,Q99733,Q15257 4 +Cysteine protease 0.434021901226656 1.281279048737879 0.2000956691938122 1.0 0.5193380642919048 41 Q96FW1,Q9Y4P1,Q06203,Q13510,P51784,Q66K14,Q8NHP8,P53634,Q8TC07,Q96K76,Q92820,Q9UDY8 12 +Acyltransferase 0.6061326333768268 1.2304797953576865 0.2185174884947665 1.0 0.5405016914213923 9 P14324,P49356,P35610 3 +Tubulin 0.6471144881000066 1.219244243142241 0.2227515040706205 1.0 0.5450641690786459 5 P04350,Q9BUF5,Q13509 3 +Extracellular structure 0.600081040429242 1.1876515032994532 0.2349707377213719 1.0 0.5570485596299939 8 O75718,Q32P28,O43290 3 +ATP-binding cassette transporter family 0.5892296360519 1.1378638646222805 0.2551773322045028 1.0 0.5809428595175842 8 P33527,Q9NUT2,P08183 3 +Small GTPase 0.4983483268653866 1.129991973872611 0.2584796064735266 1.0 0.5837828735865238 23 Q96P70,O60313,P61225,O95373,P50570,P11233,O15397 7 +ABCB subfamily 0.6226060928329152 1.1132057761887244 0.265620062476005 1.0 0.5915450274518723 5 Q9NUT2,P08183 2 +Oxidase 0.5352003558181112 1.0734553441398764 0.2830668643780885 1.0 0.6089863378090762 17 P14406,O15260 2 +Serine protease 0.4595859615681592 1.0658348536129305 0.2864983023893632 1.0 0.6133274398387515 26 Q92945,Q9Y6M1,P10619,Q9H3G5,Q9HB40,P42785,O14773,Q96AE4 8 +Extracellular matrix glycoprotein 0.6151540600283754 0.9468563744793924 0.3437119705967166 1.0 0.6701113139129592 4 Q32P28 1 +Immune response 0.5491910362129615 0.939726139366839 0.3473580535403435 1.0 0.6732012210751646 6 Q9NX40 1 +Signaling 0.5024680298189383 0.928630016382778 0.3530808605456548 1.0 0.6773997765388562 18 O15173,P43490 2 +Calcium-binding protein 0.4841495122826462 0.8991101160544269 0.3685940103057401 1.0 0.6891835183585469 20 P43307,P80303,O43852,Q02818 4 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.5907021718755863 0.8463693007516129 0.3973467587730463 1.0 0.713694571969435 4 Q9BQT8,Q9UBX3 2 +SLC35 family of nucleotide sugar transporters 0.897538461538463 0.8210041204816343 0.4116439211718949 1.0 0.7260826813173022 2 Q8TB61 1 +Calmodulin 0.4813838314754629 0.7578970448985513 0.4485126195056654 1.0 0.7527144835921307 16 P80303,O43852,Q02818 3 +Intracellular calcium-sensing protein 0.4813838314754629 0.7578970448985513 0.4485126195056654 1.0 0.7527144835921307 16 P80303,O43852,Q02818 3 +Heterotrimeric G-protein 0.5036968576709651 0.7414785039310147 0.4584033607486808 1.0 0.7607939366346335 6 P04899,P63096,Q8NHH9,Q14344,P08754 5 +Chloride channel family 0.7173992908854291 0.7293440734190008 0.4657912188625173 1.0 0.7635509118116118 3 P51797 1 +Phosphatase 0.3539377374588291 0.721048498710226 0.4708796759903471 1.0 0.7666264669374961 34 Q08623,Q9C0I1,P63151,O43681,P30154,P11117,P29218,Q9NPH0 8 +Eraser 0.491242638509494 0.6884040227828497 0.4911983912697486 1.0 0.7800131870907375 6 Q8IXJ6 1 +Protease 0.4713597131318001 0.6023455223842487 0.5469441648221363 1.0 0.80938603408362 112 P42892,P55786,Q99797,Q9HB40,Q7Z2K6,P22695,P53634,O43847,Q6P179,Q13510,P53582,P10619,P51784,Q9BYT8,Q8NHP8,P42785,O14773,Q96K76,Q9UIQ6,Q9UDY8,Q96FW1,P34913,Q9H3G5,O75844,Q9NZ08,Q96I24,Q96AE4,Q8TC07,Q96KP4,P61978,P31930,Q92945,Q06203,Q10713,Q9Y6M1,Q66K14,O00303,Q9Y4P1,Q92820,Q8N2K0,Q5BJF2 41 +Aspartic protease 0.6410652753631945 0.4784397246279381 0.6323372654362973 1.0 0.8512710858627661 3 Q5BJF2 1 +V-type ATPase 0.4321198012533145 0.4466187325887815 0.6551503678561597 1.0 0.862194682826087 8 Q9Y487 1 +Damaged DNA-binding protein 0.4793715379901753 0.4261492205933617 0.6699991163555006 1.0 0.8709203958496554 4 P54725 1 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.6195752539242876 0.4150015033199467 0.6781408026157678 1.0 0.8756119923082839 3 P08195,P30825 2 +DNA-directed DNA polymerase 0.4143677119532192 0.3789271528872866 0.7047419600920184 1.0 0.8898125732281142 10 P56282,Q9NRG0 2 +Unclassified protein 0.3839251809919477 0.2900418928656347 0.7717841885339118 1.0 0.9070239773198222 16 Q9NVE7,Q9BRR6,P30085,P52789,Q9HA64,P27144 6 +Kinase activator 0.4353698682536372 0.2899795285966742 0.7718318988688404 1.0 0.9070239773198222 4 Q16543 1 +Translation initiation factor 0.3593135375727242 0.2726310524779569 0.7851368394282447 1.0 0.9148047283463032 22 Q9UJA5,Q9Y262,P55010,P23588,Q15056,O75153 6 +Hsp90 family chaperone 0.4152658367644439 0.2360783280961267 0.8133718903580061 1.0 0.9194482997404164 4 P08238 1 +CAMKL family 0.6710769230769226 0.2205949202222164 0.8254078567088756 1.0 0.9194482997404164 2 P54619 1 +PDHK family 0.6698461538461362 0.218416887836931 0.82710430857426 1.0 0.9194482997404164 2 Q15118 1 +CDK4 subfamily 0.660307692307693 0.2020291458187105 0.839893938890506 1.0 0.9194482997404164 2 P11802 1 +Antibacterial response protein 0.6569230769230792 0.1964243422707687 0.8442780449822276 1.0 0.9194482997404164 2 P40222 1 +Translation factor 0.3161050400198683 0.1859056963131259 0.852518715064086 1.0 0.9214417915047204 27 P55010,O75153,Q9UJA5 3 +Microtubule family cytoskeletal protein 0.3081761267608213 0.1702073558376298 0.8648470670089499 1.0 0.9214417915047204 49 P04350,Q96FJ2,Q9Y496,P52732,Q15555,Q13509,Q66K74,Q8IVD9,Q9UN37,Q3KQU3,P13693,P60520,Q15691,Q13561,Q9UH99,Q9BSJ2,Q8NI77,Q9BUF5,Q96EX3 19 +DMPK family 0.3808497536945718 0.1577000094002411 0.8746931930859685 1.0 0.9222490226392588 4 Q13464,O14578,O75116 3 +SLC56 Sideroflexins 0.6298461538461552 0.1555620045211939 0.8763782762533079 1.0 0.9222490226392588 2 Q96NB2 1 +CDK1 subfamily 0.6169230769230686 0.1385369956032053 0.8898160332300793 1.0 0.925895750745744 2 P06493 1 +PAKA subfamily 0.6141538461538486 0.1350941655040149 0.8925374231440713 1.0 0.9263798431318392 2 Q13153 1 +Glycosyltransferase 0.3390233451355398 0.1190521654691868 0.9052340275515915 1.0 0.9312463078620562 16 P35573,Q93063,Q8N128,Q8N6G5,Q10472 5 +SLC12 family of cation-coupled chloride transporters 0.5996923076923134 0.1182724966769164 0.9058517488931764 1.0 0.9312463078620562 2 Q9BXP2 1 +VRK family 0.557846153846163 0.0799803600054091 0.936252876367466 1.0 0.9501370020674283 2 Q86Y07 1 +Exoribonuclease 0.3086648165279085 0.0554072629406892 0.9558140097381516 1.0 0.9685519062154122 9 Q96B26,Q9Y3B2,Q6L8Q7,Q9Y2L1,Q15024,Q13868,Q9UNK9,Q9NQT5 8 +Intracellular chloride channel (clic) family 0.4904615384615521 0.0453389434925643 0.963837146921194 1.0 0.9762001295654718 2 O00299 1 +IKK family 0.4769230769230748 0.0414229170402747 0.9669587433179888 1.0 0.9783964021842438 2 O14920 1 +MST subfamily 0.4480000000000068 0.0354445915936179 0.9717252280832878 1.0 0.9827349227857092 2 Q13043 1 +ROCK subfamily 0.4190769230769241 0.0319046271886932 0.9745481085567996 1.0 0.9850032995420208 2 O75116 1 +Lysine demethylase 0.3650353955063154 0.0309680998104116 0.9752949801281972 1.0 0.9850032995420208 3 Q8NB78,Q7LBC6 2 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..150d2d0847606818cde3d556c36d4478becaf862 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 8", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-CoA-binding protein", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Ankyrin repeat and SAM domain-containing protein 1A", "Ankyrin repeat and SOCS box protein 6", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKK family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase kinase 2", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-3", "Calreticulin", "Calumenin", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-acetyltransferase", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chloride transport protein 6", "Choline dehydrogenase, mitochondrial", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "Citron rho-interacting kinase", "ClC-3/CLCN3 subfamily", "ClC-6/CLCN6 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-C", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cystine/glutamate transporter", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 4", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Estradiol 17-beta-dehydrogenase 8", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferritin light chain", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "GC-rich sequence DNA-binding factor 2", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gamma-tubulin complex component 4", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "High mobility group protein HMGI-C", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein CDX-2", "Homeobox protein cut-like 1", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 1", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF18A", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(3)malignant brain tumor-like protein 2", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MCU family", "MHC class II regulatory factor RFX1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Meta subfamily", "Metalloendopeptidase OMA1, mitochondrial", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase kinase kinase 4", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 12", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetylgalactosamine-6-sulfatase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] 1 subunit C2", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 4", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PEK family", "PH-interacting protein", "PHD finger protein 23", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "PRKCA-binding protein", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Patatin-like phospholipase domain-containing protein 2", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Phosphotriesterase-related protein", "Pirin", "Plant homeodomain", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein Hook homolog 3", "Protein LSM14 homolog B", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c beta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene tyrosine-protein kinase src", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoblastoma-associated protein", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STE group", "STE11 family", "STE20 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 3", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase tao1", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-dependent HCO3- transporters", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sorting nexin-1", "Sorting nexin-2", "Speckle targeted PIP5K1A-regulated poly(A) polymerase", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Syntaxin-10", "Syntaxin-12", "Syntaxin-16", "Syntaxin-18", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation protein SPT3 homolog", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Very long-chain acyl-CoA synthetase", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 82", "WEE family", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD12", "ABHD6", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "ANAPC1", "ANGEL1", "ANKS1A", "ANO6", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOL2", "APP", "ARCN1", "ARFIP1", "ARG2", "ARHGDIA", "ARIH1", "ARPC1A", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCLAF1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDX2", "CEBPZ", "CENPE", "CEP170", "CEP250", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHDH", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CIT", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT4", "CNOT7", "CNP", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUX1", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAP3", "DARS", "DARS2", "DBI", "DBN1", "DBT", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FTL", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GCAT", "GCFC2", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HPRT1", "HSD17B10", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LTN1", "M6PR", "MACF1", "MAGED2", "MALT1", "MAN1A2", "MANBA", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL14", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOCS3", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL19", "MRPL22", "MRPL38", "MRPL39", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA4", "NCOA5", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK9", "NF1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OMA1", "OPA1", "ORC3", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PAICS", "PAIP1", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKAG1", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUDP", "PUM1", "PURA", "PUS1", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAI1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMN1*", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SPAG9", "SPCS2", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK26", "STK3", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAOK1", "TAP1", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TK1", "TKT", "TLE3", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM165", "TMEM259", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRIP4", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TST", "TTK", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UGGT1", "ULK3", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP34", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VRK1", "VRK2", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR82", "WIZ", "WNK1", "WRN", "WRNIP1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCC1", "ABHD12", "ACP2", "ACP6", "ADPGK", "AGL", "AK4", "ANGEL1", "APP", "ASAH1", "ASNA1", "ATG4B", "ATL2", "ATP6V0A2", "BAIAP2", "CALU", "CDC37", "CDK1", "CDK4", "CHRAC1", "CIT", "CLCN6", "CLIC1", "CLUH", "CMPK1", "CNDP2", "COX7A2", "CPVL", "CRTAP", "CSGALNACT2", "CSTB", "CTSA", "CTSC", "DCTN2", "DHCR24", "DHFR", "DIS3", "DNM2", "DYNLL2", "ECE1", "EIF3F", "EIF3L", "EIF4B", "EIF4H", "EIF5", "EPHX2", "ERAP1", "ERAP2", "ERMP1", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC7", "EXOSC8", "EXT2", "FAM177A1", "FDPS", "FN3KRP", "FNTB", "FUBP1", "FUBP3", "GABARAPL2", "GALNT1", "GGH", "GLB1L2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "HK2", "HNRNPK", "HSP90AB1", "IGF2BP2", "IKBKB", "IMPA1", "IPO7", "IPO8", "IPO9", "KDELR1", "KDELR3", "KDM1B", "KDM3B", "KHSRP", "KIF11", "KIF18A", "KIF3A", "LAMP2", "LNPEP", "MALT1", "MANBA", "MAP1S", "MAP7D1", "MAPRE1", "MAPRE2", "METAP1", "MIPEP", "MPV17L2", "MTMR12", "NAMPT", "NAP1L1", "NAP1L4", "NDUFB4", "NLN", "NPEPPS", "NRDC", "NT5C3B", "NUCB1", "NUCB2", "NUDCD3", "OCIAD1", "OLA1", "OPA1", "OTUB1", "P3H1", "PAK1", "PANK4", "PDE12", "PDK1", "PGRMC2", "PLBD2", "PMPCA", "POLE2", "PPAT", "PPP2R1B", "PPP2R2A", "PPT1", "PPT2", "PRCP", "PRKAG1", "PSMF1", "PTGES2", "PTPA", "PUDP", "RAD23A", "RALA", "RAP2B", "ROCK1", "ROCK2", "RRM2", "SART1", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SET", "SFXN2", "SIRT2", "SLC12A9", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A42", "SLC25A44", "SLC27A2", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC7A1", "SOAT1", "SPNS1", "SSR1", "STK4", "STOM", "STX10", "STX18", "STX5", "STX8", "STXBP2", "SUN2", "SURF4", "SYNGR2", "SYNJ2BP", "TBC1D15", "TBC1D9B", "TMEM165", "TMEM97", "TPP1", "TPT1", "TRMT6", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TXLNA", "TXNDC12", "UNC119B", "UQCR10", "UQCRC1", "UQCRC2", "USP11", "USP47", "VPS4A", "VRK2", "WDR34", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2c9a89814544d67cab453c74790749979179bf3 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..cf129848083a3e152def9925074f783fc5058705 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37bfd709aeca576aa3a96267477add7c647914e8196c0fa10529c546261d5672 +size 130246 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bad6ca16e26c48d5fac757582aea001c9216d96b --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff32802c2bcb83a9516dfc80a396fd2a8f028689985ded7537036566081fbc24 +size 80970 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..44bf3521f1b521d96db98d3ac624f79740a18e9c --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 812.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7f29f3f0650aadb76152177d21b94c60c1ee52ea --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8b699b09ff97a9a4eaf4ee015b0ce0ce3560b112 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.3621480347151341 0.1357461317537537 0.8920219773643101 0.9998640618108002 1.0 85 P06280,P11802,P00374,O43676,P04350,P10253,Q9Y6M9,P49721,P28074,Q8N183,P48735,O95168,P0DP25,P29218,O75306,P21964,P04035,Q9Y2I1,Q9P0J0,Q13509,Q7L0J3,O96000,Q9BU61,P31350,Q06203,O75380,P04818,P14324,O95182,P20618 30 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b7bb5b044d5b74adaed93b41b6541680b1fbd89e --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf22", "C5orf51", "C6orf89", "C8orf33", "C9orf64", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC167", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG4", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM126A", "FAM136A", "FAM162A", "FAM177A1", "FAM207A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FAU", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FN3KRP", "FNTB", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", 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0000000000000000000000000000000000000000..eefa4b8df772479210c91f228e9d41b54d5c5ce0 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..897d092f26cc8601f50dbca0baa36b6f08b14da4 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,46 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Sphingolipid metabolism 0.8709507005371524 2.4135400378553995 0.0157983920399733 0.9332744841175948 0.6182805265185923 9 Q13510,P17900,P04062,Q06136,P07602 5 +Vision 0.7611735428546764 1.871134061124963 0.0613265015227599 0.9999787443384576 0.6182805265185923 6 P50897,Q9H6K4,Q9H0F7 3 +Sensory transduction 0.7611735428546764 1.871134061124963 0.0613265015227599 0.9999787443384576 0.6182805265185923 6 P50897,Q9H6K4,Q9H0F7 3 +Adaptive immunity 0.6997622883674933 1.778866984698564 0.075261572006396 0.9999983280861025 0.6182805265185923 13 Q96FW1,Q6P179,P10321,P01889,Q9NZ08,P04083 6 +Respiratory chain 0.4559975738316351 1.614510095469882 0.1064168288527707 0.9999999950688662 0.6958023424988853 32 O75380,P00403,O43676,Q6DKK2,Q9UDW1,O95168,O95182,O75306 8 +Sterol metabolism 0.5586424432601121 1.507490326765188 0.1316850214703218 0.9999999999624042 0.7593225472899082 23 P61916,P04035,O15118,Q15392,P35610,P37268,Q14739,P04062,Q16850 9 +Cholesterol metabolism 0.5597647117096164 1.45017711571616 0.1470091348719546 0.999999999998178 0.7593225472899082 22 P61916,P04035,O15118,Q15392,P35610,P37268,Q14739,P04062,Q16850 9 +ER-Golgi transport 0.463537362350139 1.3664327864543016 0.1718031638990471 0.999999999999988 0.7891683629147703 51 Q9P2W9,Q9Y282,O15498,Q8N6T3,P24390,Q15437,O43731,O95070,Q969X5 9 +Electron transport 0.4474336377849525 1.32846561607284 0.1840243352394157 0.999999999999999 0.7891683629147703 45 Q9H1E5,P00403,O75380,O43676,Q6DKK2,Q9UDW1,O95168,O95182,O43169,O75306 10 +Amino-acid transport 0.6237176294762933 1.29601299664183 0.194971007308355 1.0 0.7891683629147703 8 Q96NB2,P30825,Q96H78 3 +Notch signaling pathway 0.6159463359486936 1.24709981666429 0.2123609001759223 1.0 0.8310807158500226 7 Q9NVX2,Q9UBV2,Q92542,P05067 4 +Steroid metabolism 0.5059239791298995 1.239654416449569 0.2151032441023588 1.0 0.8310807158500226 24 P61916,P04035,O15118,Q15392,P35610,P37268,Q14739,P04062,Q16850 9 +Glyoxylate bypass 0.980615384615384 1.1012870288426269 0.2707717547353598 1.0 0.944259048551632 2 P48735 1 +DNA excision 0.6422880144409956 1.0599783931126037 0.2891544292618562 1.0 0.944259048551632 4 Q9UQ84 1 +Autophagy 0.3997007417824336 1.03500843877408 0.3006649702195125 1.0 0.9465378692095766 31 Q9H0U4,Q9NRR5,Q9BXS4,Q9NQ88,Q13137,Q9Y4P1,Q9P253,Q6PHR2,Q8IXJ6,P13473 10 +Lipid degradation 0.4970400923926869 0.7936231000849214 0.4274148803646389 1.0 1.0 14 Q9H6V9,Q8NCG7,Q8NCC3,Q8NHP8 4 +Meiosis 0.4748226055177336 0.7240284350335278 0.4690482782190845 1.0 1.0 16 Q9UH99,Q9UQ84 2 +Zinc transport 0.8646153846153755 0.7152787727149932 0.4744368025166738 1.0 1.0 2 Q8TAD4 1 +Cilium biogenesis/degradation 0.4108891782252919 0.5882068347013002 0.5563934703769906 1.0 1.0 23 Q9H4M9,A6NIH7,Q9H0F7 3 +Sterol biosynthesis 0.438960238137816 0.5125700649446783 0.6082520975222079 1.0 1.0 14 P04035,Q15392,P37268,Q14739,Q16850 5 +Immunity 0.4048881597895484 0.5110740826626535 0.6092991831336056 1.0 1.0 78 Q96FW1,P10321,Q6P179,Q9NUD5,P01889,Q8IV08,Q9UQ84,P46379,Q9NZ08,P04083,O00584,Q9UDY8,Q8IXJ6 13 +Cholesterol biosynthesis 0.4404965823586749 0.5079225729157322 0.6115076436871394 1.0 1.0 13 P04035,Q15392,P37268,Q14739,Q16850 5 +Translocation 0.3510592245773533 0.4927596547420134 0.6221824210620994 1.0 1.0 48 Q99595,Q9NS69,Q15629,Q9Y584 4 +Aromatic hydrocarbons catabolism 0.7516923076923101 0.3932858995762307 0.6941083314303833 1.0 1.0 2 P34913 1 +Detoxification 0.7516923076923101 0.3932858995762307 0.6941083314303833 1.0 1.0 2 P34913 1 +Inflammatory response 0.4159414037539996 0.3851451361602958 0.7001298886848777 1.0 1.0 10 Q8IV08 1 +Oogenesis 0.4092267695327857 0.3638343306121033 0.7159817249282527 1.0 1.0 6 Q86U44,Q15645,Q96RD7,Q9Y5A9 4 +Asparagine biosynthesis 0.7360000000000021 0.3552774766245478 0.7223817273247293 1.0 1.0 2 Q9NWL6 1 +Lipid transport 0.3752439408893095 0.3293220433727239 0.7419122843320187 1.0 1.0 21 Q9BQE5,O15118 2 +Antiport 0.3926071928516588 0.2985344529828072 0.7652952845551311 1.0 1.0 8 P41440,P51797 2 +Gastrulation 0.7052307692307612 0.2867181171129288 0.7743281643096529 1.0 1.0 2 P63244 1 +Steroid biosynthesis 0.3648323713212614 0.2592795959408558 0.7954195213233857 1.0 1.0 20 P04035,P14324,Q15392,P37268,Q14739,Q16850 6 +Biomineralization 0.6775384615384624 0.2322663798638153 0.8163311234224824 1.0 1.0 2 Q6P4Q7 1 +Tricarboxylic acid cycle 0.3600377617076057 0.2227959653263274 0.8236943082961616 1.0 1.0 19 P48735 1 +Symport 0.3626001232285911 0.2108182282716247 0.833029114095075 1.0 1.0 6 Q9Y6M7,Q9H936,Q00325,Q15758,P55011 5 +Spermatogenesis 0.3155709570505255 0.1531777268042834 0.8782581218101149 1.0 1.0 26 Q9Y2W6,Q86U44,Q15019,Q9Y5A9,Q16181,Q9BY67,P46379,Q9H0H5,Q9H8Y8,Q15645 10 +Angiogenesis 0.338648007426478 0.1161959964734414 0.907497209613184 1.0 1.0 12 Q9BXJ9 1 +Pyrimidine biosynthesis 0.34238612141623 0.1122253086924786 0.9106447624908214 1.0 1.0 5 P30085 1 +Chemotaxis 0.3371547785911395 0.1022303774139955 0.9185738163738186 1.0 1.0 5 Q9Y6N7,O94813 2 +Fertilization 0.5061538461538514 0.0509693249198083 0.9593499639324674 1.0 1.0 2 Q08431 1 +DNA synthesis 0.3881194213604239 0.0394801827342637 0.968507553084303 1.0 1.0 3 P35232,P04183 2 +Serine biosynthesis 0.4544615384615548 0.0365353343444673 0.970855504774587 1.0 1.0 2 O43175 1 +Methionine biosynthesis 0.3431825176977577 0.0255844183693986 0.979588814342884 1.0 1.0 3 Q9BV20,Q99707 2 +Ion transport 0.2966824203029243 0.0026503895458259 0.9978852975770832 1.0 1.0 59 Q14847,P21796,P45880,P24539,O75964,Q15904,Q8TAD4,Q9NUT2,Q9Y277,Q9Y487,Q9H0H5,Q15043,Q93050 13 +Exocytosis 0.2981787720717654 0.002590402896168 0.9979331598343696 1.0 1.0 16 P11233,Q15833,Q8IYI6,Q9UPT5 4 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..356c8e9ad4f377d2aa0ab9de6caa4b9e8ce3cbc7 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Iron storage", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ACTR8", "ADA", "ADAR", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APIP", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8A", "ARMC10", "ARMC9", "ARMT1", "ARVCF", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRIP", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CAMK2G", "CAMLG", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP2", "CBR4", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC94", "CCNB1", "CCNC", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPU", "CENPV", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CLU", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "COG2", "COG3", "COG5", "COG7", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRAT", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DCAF1", "DCAF7", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FOXRED1", "FTL", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCC2", "GCFC2", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GHITM", "GID8", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HERC2", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGXB4", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH2", "INA", "INCENP", "INTS13", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1B", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "L3MBTL2", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MALT1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL14", "METTL3", "MFAP1", "MFGE8", "MFN2", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMS19", "MOCS3", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MRE11", "MRI1", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R2", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "PPAT", "PPCDC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP5C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN3", "RMND1", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMU1", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SPAG5", "SPATA5", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STK26", "STK3", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNGR2", "SYS1", "TACC3", "TAF6L", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARDBP", "TARS", "TARS2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TDRKH", "TECR", "TEFM", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TK1", "TLE3", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM14C", "TMEM206", "TMEM214", "TMEM38B", "TMEM59", "TMF1", "TMLHE", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TP53RK", "TPI1", "TPR", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TUBB2B", "TUFM", "TUT1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VPS13A", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WIPI2", "WRAP53", "WRAP73", "WRN", "WRNIP1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YIF1A", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "ZC3H11A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZMYM2", "ZNF131", "ZNF280C", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB8", "ANXA1", "APOL2", "APP", "ARFGAP1", "ARL6", "ASAH1", "ASNSD1", "ATG4B", "ATP5F1", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "BAG6", "CADM1", "CALCOCO2", "CLCN6", "CMPK1", "CNNM4", "COX2", "CYB5B", "CYP51A1", "DAGLB", "DHCR24", "EHD1", "EPHX2", "ERAP1", "ERAP2", "ERGIC1", "ERGIC3", "EXO1", "EXOC7", "EXOC8", "FDFT1", "FDPS", "GBA", "GM2A", "GORASP2", "HLA-B", "HLA-C", "HMGCR", "IDH2", "KDELR1", "KDELR3", "KDSR", "LAMP2", "LASP1", "LBR", "LDAH", "MALT1", "METTL3", "MFGE8", "MRI1", "MTR", "NAA15", "NCSTN", "NDUFA7", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NLE1", "NPC1", "NPC2", "OPA3", "OTUB1", "PANX1", "PHB", "PHGDH", "PLA2G15", "PLBD2", "PLD3", "PPT1", "PSAP", "RAB1B", "RACGAP1", "RACK1", "RALA", "RNASET2", "ROBO1", "SEC23B", "SEL1L", "SEPT2", "SEPT7", "SFXN2", "SIRT2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A22", "SLC25A3", "SLC25A44", "SLC30A5", "SLC39A14", "SLC4A7", "SLC7A1", "SLIT2", "SOAT1", "STX18", "STXBP2", "SUN2", "TDRKH", "TIGAR", "TIMM17A", "TIMM22", "TK1", "TMEM59", "TMX4", "TOMM22", "TRAM1", "TRIP13", "TTC19", "UBQLN4", "ULK3", "UNC119B", "UQCR10", "VDAC1", "VDAC2", "VDAC3", "VPS18", "YIF1A", "YKT6", "YTHDF2", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8e32e944730f352ea306a3ee2df634996bd5d0b4 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Amyotrophic lateral sclerosis", "1": "Proto-oncogene"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..59046e7b4dd4e4be7ca2b0a69fa687838a04cfb7 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:420332e0331d787ea50013af77aa3689b7a90d5f5858cd31cd23dc05d3277a81 +size 142420 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..03621a057f8c4cfb9f85fa94ed7b55b693b87325 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:751012afc22d7e3acce48cd0be4831ce29e4a1eeabeaffa207787a927478a672 +size 144237 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5999d597efb7abb6131bc988ed6bf3daf6715356 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71c600fb0ffc06c71a2a3c84ea7499f0357e9fe8555e802b0e04f5e817cce25a +size 76039 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7cec94d5dec32ebe21338aeee4e94336c947a43a --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Gangliosidosis 3 5 2.4471328659135345 0.0143997744876611 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 5.758824600398199e-07 0.0238038053541035 0.0009157120850054 1.7035552164727766e-06 2.725609341406673e-05 +Mucopolysaccharidosis 2 5 2.187492734003832 0.0287065730703623 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0009412478616896 0.0516364610584135 0.0048484802924912 0.0020533662966424 0.0143213925416526 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6bd11173027dfc6023d764541bc574bbaed96a41 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 117, + "title": "Average number of proteins per term", + "value": 22.128205128205128 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c15f04732a8b50ea068dcf4f7037412890b347d5 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c83641502b1ffeee6ff5219ee9079c1edad2309f --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Gangliosidosis 0.9412258516136192 2.4471328659135345 0.0143997744876611 0.8167715447345656 0.4735647217009471 5 P17900,P16278,P07602 3 +Neuronal ceroid lipofuscinosis 0.97871635271638 2.4450413972421656 0.01448355163284 0.8185848216935996 0.4735647217009471 4 P50897,O75503 2 +Mucopolysaccharidosis 0.8762714209275055 2.187492734003832 0.0287065730703623 0.9668866882224372 0.4735647217009471 5 P54802,P15586 2 +Glycogen storage disease 0.6863206353755482 1.6248747371263406 0.1041892521262577 0.9999974337235026 0.9635808728149728 10 P10253,P13473 2 +Ichthyosis 0.5979363908988499 1.177811604822545 0.2388717211618709 0.9999999999999865 1.0 8 P51648,Q10567,P04062 3 +Ehlers-Danlos syndrome 0.8282646448644604 1.135657237911224 0.2561000437659388 0.9999999999999992 1.0 3 Q8NCH0 1 +Gaucher disease 0.9738461538461518 1.077933878666419 0.2810632650874387 1.0 1.0 2 P07602 1 +Niemann-Pick disease 0.939999999999998 0.9623441982378808 0.3358767341135167 1.0 1.0 2 O15118 1 +Amyotrophic lateral sclerosis 0.5295341740654103 0.9162459204006628 0.3595379254091397 1.0 1.0 12 P07737,Q9NRR5,Q9UQN3,P35637,Q9H9T3 5 +Ciliopathy 0.4806578654612575 0.7541400815790286 0.4507651119692917 1.0 1.0 16 Q96EX3,Q9H0F7 2 +Craniosynostosis 0.7205380512376365 0.7403282656422426 0.4591008339676505 1.0 1.0 3 P07237 1 +Lissencephaly 0.478513255776172 0.6444574577675796 0.5192788359348528 1.0 1.0 9 Q6ZXV5,O43505 2 +Hirschsprung disease 0.8261538461538315 0.5974679173308728 0.5501950206983524 1.0 1.0 2 P42892 1 +Proto-oncogene 0.3425851356690459 0.5243167768583992 0.6000582299513222 1.0 1.0 41 Q01105,Q92733,Q01844,P46108,Q92804,Q06136,P35637 7 +Spinocerebellar ataxia 0.4467374574514243 0.5079526771763865 0.61148653098105 1.0 1.0 9 O14773 1 +Parkinson disease 0.4207781060424891 0.4025834512517017 0.6872546858123378 1.0 1.0 9 P04062 1 +Schizophrenia 0.7384615384615416 0.3611087392074725 0.7180181604890405 1.0 1.0 2 P21964 1 +Congenital disorder of glycosylation 0.3790510639121527 0.3266690089527211 0.7439182426328566 1.0 1.0 20 Q8N511,Q15904 2 +Nephronophthisis 0.7141538461538441 0.3057537651139969 0.7597921336592308 1.0 1.0 2 O15078 1 +Parkinsonism 0.3906933533286204 0.2959636319897537 0.7672578552641929 1.0 1.0 13 P04062,Q709C8 2 +Rhizomelic chondrodysplasia punctata 0.5628364637065638 0.2679821298172513 0.7887130741488482 1.0 1.0 3 O00116 1 +Nemaline myopathy 0.6827692307692359 0.2420045872399161 0.8087766087644206 1.0 1.0 2 Q9Y281 1 +Dystonia 0.3581131015953738 0.1865690587236956 0.8519985282981344 1.0 1.0 8 Q15043,P35270 2 +Obesity 0.350930635222574 0.1656890424917053 0.8684016696863499 1.0 1.0 8 Q9Y4W2,Q13049,Q9H0F7 3 +Hereditary nonpolyposis colorectal cancer 0.4855384615384642 0.0438207359949662 0.9650472980256376 1.0 1.0 2 P43246 1 +Joubert syndrome 0.3841181902123786 0.0377625425789844 0.9698770097486478 1.0 1.0 3 O15078,P36405 2 +Cockayne syndrome 0.4230769230769187 0.0322819083718192 0.9742472367130552 1.0 1.0 2 P18074 1 +Xeroderma pigmentosum 0.4230769230769187 0.0322819083718192 0.9742472367130552 1.0 1.0 2 P18074 1 +Meckel syndrome 0.3667692307692239 0.0291304375479862 0.9767605604407048 1.0 1.0 2 O15078 1 +Amelogenesis imperfecta 0.3153846153846074 0.0284371432277251 0.9773135001593136 1.0 1.0 2 Q6P4Q7 1 +Leukodystrophy 0.3067402852887076 0.026780113541238 0.9786351146245148 1.0 1.0 19 P07602,P49770,Q9UI10 3 +Cushing syndrome 0.3466995083915248 0.0263037493723325 0.979015064380654 1.0 1.0 3 P10644 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3db4510277311291a928b938c175d91fb73b667c --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD12", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ANAPC1", "ANK3", "ANKLE2", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA7", "AP1B1", "AP1S1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARMC9", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATM", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCKDHA", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRI3BP", "BUB1B", "C12orf57", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CAMLG", "CANT1", "CANX", "CAPN1", "CAPN5", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCNB1", "CCT5", "CD320", "CDC16", "CDC20", "CDC27", "CDC34", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDX2", "CENPE", "CENPF", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIT", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "COA3", "COA7", "COG2", "COG5", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRAT", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DARS", "DARS2", "DBI", "DBN1", "DBT", "DCK", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "ECT2", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "EPB41", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM126A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FAT1", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FNTB", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALNS", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATB", "GATC", "GBA", "GCDH", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNPAT", "GNS", "GOLGA5", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GPRASP2", "GPT2", "GRB2", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HMBS", "HMGA1", "HMGA2", "HMGB3", "HMGCL", "HMGCR", "HMGXB4", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IFT52", "IGBP1", "IGF2R", "IKBKB", "ILF3", "ILK", "IMPA1", "IMPAD1", "IMPDH2", "INF2", "INTS1", "IPO7", "IRS4", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KTN1", "L2HGDH", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MALT1", "MAN2B1", "MAP1A", "MAP1B", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MARS", "MARS2", "MATR3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED23", "MESD", "METTL14", "MFGE8", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCOA4", "NCSTN", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NF1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OMA1", "OPA1", "OPA3", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAK1", "PANX1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PCNT", "PDAP1", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP2R1A", "PPP2R5D", "PPP5C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD54B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RFT1", "RHEB", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "ROCK1", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC3A2", "SLC7A11", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TK1", "TKFC", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM38B", "TMEM43", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM25", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRMT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TSR2", "TTC19", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFSP2", "UGDH", "UGP2", "UMPS", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRQ", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WDCP", "WDR1", "WDR26", "WDR34", "WDR36", "WDR5", "WFS1", "WIPI2", "WNK1", "WRAP53", "WRN", "XPNPEP3", "XPO1", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", 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sha256:61635e07cc6e242c598964c4c8e07502d6a3043006cbba17124112ae4683c51d +size 130776 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..00fc2878e0942dfa4e552732f5c670cb25e98fee --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bbcbae37cd5ff07d22b30cfffd9d43ff452520dd4bb82ac368d40431015ca6c +size 78122 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..535bb1347e109899720239f8e07cf9146bd1f538 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 16 36 2.971049659545879 0.002967837868107 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.3230307979925663 0.1182182962859897 0.0958446637688343 0.2674523655880978 0.3402864129139207 +Carboxypeptidase 3 6 2.4609600488720407 0.0138565794929115 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0001357736334811 0.0022827689145391 1.0516191954151127e-05 0.0003832983840783 0.000548875622046 +Glycosidase 9 20 2.416931000667512 0.0156519838076396 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 4.480398511166854e-09 0.187449079081247 0.0082729445560879 5.946855875018689e-08 4.77131294925026e-06 +Metalloprotease 11 27 2.3543269328271 0.0185562824461937 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0043925419926 0.2443632781182481 0.0186371594327644 0.0027943802514918 9.700192435637282e-05 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cf22a0eaef418a82a37623c42ba5dcf9159d5fe9 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 39.175257731958766 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1de38bf3b41132810fd7919bfffea8a7024c7fc2 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..16fbd347948a5202776ae15aead4202034deaf60 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,27 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6392452376544753 2.971049659545879 0.002967837868107 0.2504695321032751 0.2234973679945575 36 P11717,P30825,O15173,P11279,O15118,Q9Y6N7,P24390,Q9NS69,O43731,Q15375,Q14108,Q9Y5M8,P20645,Q14739,Q8WTV0,O14786 16 +Carboxypeptidase 0.904129523430968 2.4609600488720407 0.0138565794929115 0.7416622317947887 0.2234973679945575 6 P10619,Q9HB40,P42785 3 +Glycosidase 0.7538727907895963 2.416931000667512 0.0156519838076396 0.7835183815100466 0.2234973679945575 20 P06280,P54802,Q8IW92,P16278,P04066,P10253,P04062,Q9BTY2,O00462 9 +Metalloprotease 0.6374256805088602 2.3543269328271 0.0185562824461937 0.8374661823224867 0.2234973679945575 27 Q6P179,Q99797,P55786,P42892,Q9BYT8,O75844,P09960,Q9NZ08,Q9UIQ6,Q96KP4,O43847 11 +Porin 0.8813518104606566 2.0581749925596364 0.0395733382523593 0.9800919763807936 0.2952779854214503 4 P45880,P21796 2 +Serine protease inhibitor 0.7587410877666791 1.5512845771038153 0.1208335012048245 0.9999962424940751 0.5946809814613436 4 P05067,Q06481 2 +Aminopeptidase 0.6404450383139707 1.4593072590272194 0.1444805583626656 0.9999997331306604 0.5946809814613436 12 P53582,P55786,Q9NZ08,Q9UIQ6 4 +Protease inhibitor 0.6609852093330413 1.4497166081721902 0.1471375624234252 0.999999802638804 0.5946809814613436 7 P04080,P05067 2 +Host cell receptor for virus entry 0.6119667092471208 1.4105685305052529 0.1583718761974735 0.9999999454665188 0.6143417563444951 15 Q14108,O15118,Q8WTV0 3 +Monooxygenase 0.8949992391976752 1.3895389533608802 0.1646689243809986 0.999999973679878 0.6143417563444951 3 Q6UW02 1 +Glycosyltransferase 0.3973043832466006 1.0865623677792695 0.2772302639066841 0.999999999999979 0.7320720988140417 34 P43490,Q93063,Q06203,P37287,P04062,Q10472,O43505,Q13126 8 +Threonine protease 0.7950138504155143 1.0107884953005115 0.3121176706363413 0.9999999999999998 0.7320720988140417 3 P28074,P28072 2 +Protease 0.4786928575722713 1.008978301998473 0.3129850403598357 1.0 0.7320720988140417 84 Q96FW1,Q4J6C6,P42892,P10619,Q9H3G5,Q9HB40,P55786,P53582,P28072,Q99797,O75844,P42785,P09960,O14773,Q9NZ08,Q9UIQ6,Q9UDY8,O43847 18 +Heparin-binding 0.5512265522048352 0.9552577805931676 0.3394473523417303 1.0 0.7320720988140417 7 P05067 1 +Guanine-nucleotide releasing factor 0.4690414865242151 0.7769811600426583 0.4371698857298542 1.0 0.8481095783159174 19 P80303,Q02818 2 +Transducer 0.5040073982737334 0.7511177167485195 0.4525818142680875 1.0 0.8593170044642189 8 P04899,P63096,O14654,P02786,P19174,Q14344,P08754 7 +Calcium channel 0.6949830717143762 0.6522131047341309 0.5142637071801601 1.0 0.9069741744813732 3 Q8NE86,Q96RD7 2 +Dioxygenase 0.4639782512401836 0.6310805563407857 0.5279878537245817 1.0 0.914550389487222 14 Q9NVH6,O15460 2 +Serine protease 0.4669591682675771 0.594028286642417 0.5524931938753372 1.0 0.9239972380328916 9 O14773 1 +Endonuclease 0.4141341379179075 0.4810057116476147 0.6305124393257642 1.0 0.9839277308711338 19 Q9UQ84,O00584,Q15631 3 +Translocase 0.3864817065985818 0.4141804040536517 0.6787419918831958 1.0 0.9839277308711338 22 Q9HD20,P00403,P33527,O75306,P08183 5 +Acyltransferase 0.3161674821085981 0.3750402291400331 0.7076305480589493 1.0 0.9839277308711338 37 Q86UY6,Q8NCC3,P23786,Q96N66,P35610,Q9HCL2 6 +Rotamase 0.365652363214103 0.3044712877517054 0.760768864075619 1.0 0.9839277308711338 22 Q8WUA2,P30414,Q15257,Q96AY3,O43447,Q9Y237,Q9NWM8,Q9Y680,Q9Y3C6 9 +Muscle protein 0.3575138520905173 0.1899773489856829 0.8493268801739275 1.0 1.0 7 P46020 1 +Protein phosphatase inhibitor 0.4880207433252889 0.1284918419477205 0.897759753892492 1.0 1.0 3 O43768 1 +Integrin 0.3763076923076852 0.0294126706425174 0.9765354674659548 1.0 1.0 2 P06756 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..76ba19f984bf10d8ba485095babc92e1d69cdbb6 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "ANKHD1", "ANKRD17", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APIP", "APLP2", "APP", "APRT", "AQR", "ARFGAP1", "ARFGEF1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BCKDHA", "BCLAF1", "BCS1L", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BSG", "BTAF1", "BTF3", "BUB1B", "BZW1", "BZW2", "C12orf43", "CAD", "CADM1", "CALD1", "CALR", "CAMK2D", "CAMK2G", "CAMKK2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX2", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPU", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHKA", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CIT", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CROT", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF7", "DCD", "DCK", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ESD", "ESPL1", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFRD1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "IVD", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC4", "KRR1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1S", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MATR3", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA4", "NCOA5", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NF1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "ORC3", "OTUB1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PCYOX1L", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDSS1", "PDSS2", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICK1", "PIGA", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMF1", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP5C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKCB", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD50", "RAD54B", "RAI1", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO4", "RFC1", "RFC3", "RFX1", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIPK1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIN3A", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SPATA5", "SPCS2", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSRP1", "STAT1", "STAT3", "STAU1", "STK26", "STK3", "STK4", "STMN1", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TMCO1", "TMEM109", "TMEM126B", "TMEM206", "TMEM38B", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TTF2", "TTK", "TUFM", "TUT1", "TWF1", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBR2", "UBR4", "UBR5", "UBTF", "UCHL5", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXS1", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WRAP53", "WRN", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZFR", "ZMPSTE24", "ZNF131", "ZNF280C", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCC1", "APLP2", "APP", "ATP13A1", "B4GAT1", "CNDP2", "COX2", "CPT2", "CPVL", "CSTB", "CTSA", "CYP20A1", "ECE1", "ENSA", "EPHA7", "ERAP1", "ERAP2", "EXO1", "EXT2", "FKBP10", "FKBP14", "FKBP7", "FUCA1", "FUCA2", "GAA", "GALNT1", "GBA", "GLA", "GLB1", "GLB1L2", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GPAM", "IGF2R", "IRS4", "ITGAV", "KDELR1", "KDELR3", "LAMP1", "LBR", "LNPEP", "LTA4H", "M6PR", "MALT1", "MANBA", "MBOAT7", "MCU", "METAP1", "MIPEP", "MTAP", "NAA40", "NAGLU", "NAMPT", "NDUFS2", "NKTR", "NLN", "NPC1", "NPEPPS", "NRDC", "NRP1", "NUCB1", "NUCB2", "OTUB1", "P4HA2", "PANX1", "PGRMC2", "PHKA1", "PIGA", "PIN4", "PLA2G15", "PLCG1", "PPAT", "PPIH", "PPIL1", "PPIL4", "PRCP", "PREPL", "PSMB5", "PSMB6", "PTPA", "RNASET2", "ROBO1", "SCARB1", "SCARB2", "SCPEP1", "SLC7A1", "SOAT1", "SRPRB", "TFRC", "TMLHE", "TOMM22", "TPP1", "TSN", "VDAC1", "VDAC2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5af2af629ddf16c6e41884874fb2f96fa2805f00 --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted secreted proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..47eb245e92d4d8c65ed17ba9d1c4bc76e96eb258 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0551252866d6c3d91022f984519b221f1ff0aa7d0d8ad68a42fcbfd3b07e0811 +size 195751 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..809a95ab06761925b37d237c57e393c846191dcc --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted secreted proteins", "1": "CD markers"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7e3ecb4705f74a37297d0d8fd8fe1c9565281b89 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:871a6778e9444ff409f8019d9d8918f10e7a321972f5f3962a72c720c5f3cd64 +size 135535 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..31a8c5c6c7e89ef8238b101b01c8fc544804f720 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db5662c99fd7dbf9b339061fde5325a05fcb5e018f43e2aca54eeff95d647e08 +size 139454 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..54581fd0fee99ec3398853116b2f312da47ea726 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8baa9bd5034e9933377e8481c32f89627ad3a963cce2405f8085cb90faf10b60 +size 84022 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..aa573be29f6a44b5e5fb6b9ca36845b5b11c0f94 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted secreted proteins 17 55 2.866444718966121 0.0041511065135495 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.0044974317184791 0.001720850770709 0.0156096381318318 0.0024776005259076 0.040950561109388 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4e3aaada17125d2852d23e36b64510252a281efe --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 521.7 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3c27f65648bf112d2e2008de68bfc86e51222e13 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ea585ccea0fc8bf15afeaa35dc1ef422ea1f073f --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted secreted proteins 0.6657125221922842 2.866444718966121 0.0041511065135495 0.0798282351889068 0.0415110651354955 55 Q8NBM8,P80303,P43490,O75718,Q8IW92,Q9UM22,P61916,P05067,Q9HB40,Q08380,Q8WUJ1,Q9NZ08,Q02818,P04083,Q9BTY2,O00584,O60888 17 +Candidate cardiovascular disease genes 0.5596318265888248 1.0138326994559512 0.3106625893149735 0.9994130015286912 0.8876073980427814 9 P06865 1 +CD markers 0.4790220521915836 0.7456830469658462 0.4558589025243462 0.9999948211830092 0.9117178050486924 16 P11717,P11279,Q9Y624,O14786,P08183,P13473 6 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c5b1c6c0de266a536e4fdc413ac935a8960132b5 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL5B", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC10", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ARVCF", "ASAH1", "ASB6", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCKDHA", "BCL2L13", "BCLAF1", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C3orf58", "C5orf22", "C5orf51", "C6orf89", "C8orf33", "C9orf64", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBR4", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC138", "CCDC167", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC16", "CDC20", "CDC23", "CDC27", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHDH", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "CORO1C", "COTL1", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUL7", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBI", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHHADH", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM126A", "FAM136A", "FAM162A", "FAM177A1", "FAM207A", "FAM208A", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAT1", "FBL", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FN3KRP", "FNTB", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IER3IP1", "IFRD1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPA1", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF15", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED24", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL3", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL22", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIGA", "PIGK", "PIGS", "PIGT", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABGGTA", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD54B", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLC7A11", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSNA1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM161A", "TMEM165", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC26", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRAP73", "WRN", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF131", "ZNF280C", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCB1", "ANXA1", "APP", "CRTAP", "CUTA", "CYB5D2", "EPDR1", "ERAP1", "F11R", "FUCA2", "GLB1L2", "HEXA", "IGF2R", "LAMP1", "LAMP2", "LGALS3BP", "NAMPT", "NPC2", "NRP1", "NUCB1", "NUCB2", "PCYOX1L", "RNASET2", "SCPEP1"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f920012874c7b40925a2fe87432ecd2087476240 --- /dev/null +++ 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sha256:4cb0ef338cd22eb730b1ec6b12ce0d6420b118e09b7719fae2f387eb62bbf72e +size 144587 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..205d8fad537c2ccc8b952fcd87a9a6f0c4f453d5 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1fe41b660d8052511f3d497bcf3619d81e75753ac4d634017e0b6ffa31884d62 +size 72684 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..631df74a7374e48df7a6ec3ac2eeecd28ac09f1f --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3252, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 150.57575757575756 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7660813a59175dbf2682ac250fca609017767c24 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C211/C211_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4400d7cbbb36919341b8fea56ba82e881476c62f --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Focal adhesion sites 0.457430519711531 1.2051859988960194 0.2281315061796038 0.999805495627138 1.0 28 Q14847,Q9Y487,Q9H1I8,O60888,P08183 5 +Lysosomes 0.4704457213646278 0.647060554331923 0.5175927533207196 0.999999999964301 1.0 13 Q8WTV0 1 +Mitotic spindle 0.3480826979564577 0.2660602846156649 0.7901927811691263 1.0 1.0 24 Q8NEM2,Q8IX90,Q13509,Q15477,Q96R06,P52732 6 +Centriolar satellite 0.2996585007536805 0.206995932620415 0.8360130350100787 1.0 1.0 30 Q9Y4W2,Q15907,Q7Z4H7,O15344,Q86UY6,Q03518,P11413,O43169,Q86VS8,Q00013 10 +Golgi apparatus 0.5002034011512801 0.1977002965355642 0.843279557691994 1.0 1.0 174 Q8IYR2,Q10567,P80303,Q93063,O43493,P24390,Q9HB40,Q9HD45,P50897,Q8N4Q0,Q8IZA0,Q96A49,Q5VW38,P16278,Q6P179,Q8N6T3,Q9UBU6,Q92538,O60637,Q8TAD4,A1L0T0,O15127,O95070,Q02818,Q15043,O43290,P11717,O60499,Q7RTS9,Q8NBN3,Q96RQ1,Q9H2V7,Q14CX7,Q8IXU6,Q969S3,Q9NWM8,P09601,O95456,Q93050,Q8NCH0,Q92896,Q13190,Q9C005,Q9H0U4,A4D1U4,P04439,O00461,O15260,O75955,P05067,O75071,O43760,Q9BSL1,Q9HC07,Q9H8Y8,P61966 56 +Cell Junctions 0.3062595910826269 0.1688522399242996 0.8659128666908522 1.0 1.0 48 P43490,Q9UJA5,O43657,Q4VCS5,O15126,P33527,Q9BW91,O00192,Q6UW02 9 +Endosomes 0.3004502858964877 0.0214735982545905 0.982867864146572 1.0 1.0 12 Q8IY95,O75436,P09496,O60749,P02786,Q13596,Q9P2R3 7 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f6f9a42c308fcce4a56df3b13720773ff8333b42 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGEF1", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASNSD1", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATM", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATRIP", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCCIP", "BCL2L13", "BCLAF1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRD8", "BRI3BP", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf22", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK2D", "CAMK2G", "CAMKK2", "CAMLG", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP2", "CAST", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC167", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC94", "CCDC97", "CCNB1", "CCNC", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD3EAP", "CD47", "CDC123", "CDC20", "CDC27", "CDC34", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDS2", "CDV3", "CDX2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPF", "CENPI", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG3", "COG5", "COG7", "COIL", "COLGALT1", "COMMD1", "COMMD10", "COMMD4", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COTL1", "COX4I1", "COX5B", "COX6B1", "COX6C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRAT", "CRK", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBT", "DCAF1", "DCAF7", "DCAKD", "DCK", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT2", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "EPB41", "EPB41L2", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM126A", "FAM136A", "FAM162A", "FAM177A1", "FAM207A", "FAM208A", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FN3KRP", "FNTB", "FOCAD", "FOXRED1", "FSCN1", "FTL", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT2", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA3", "GHITM", "GID4", "GID8", "GIGYF2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HGS", "HIBCH", "HINT2", "HIP1", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMGXB4", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFRD1", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRGQ", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL2", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LZIC", "LZTFL1", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A2", "MAN2A1", "MAN2B1", "MANBA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K4", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED14", "MED16", "MED21", "MED23", "MED4", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL17", "METTL7B", "METTL9", "MFAP1", "MFGE8", "MFN1", "MFN2", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA4", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4", "NEFL", "NEFM", "NELFCD", "NELFE", "NEMF", "NES", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OMA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAOX", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PICK1", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2L", "POLR3A", "POLR3B", "POLRMT", "POP1", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP4R3B", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA2", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTER", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "QRSL1", "QSOX2", "R3HCC1", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB6A", "RAB7A", "RAB9A", "RABEPK", "RABGAP1", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM8A", "RBMX", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RHBDD2", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF20", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROBO1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD2", "RRAS2", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A11", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRC", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSFA2", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK3", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STRN3", "STT3B", "STUB1", "STX10", "STX12", "STX16", "STX18", "STX5", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TKFC", "TKT", "TLE3", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM126A", "TMEM126B", "TMEM161A", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIM32", "TRIM33", "TRIP11", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TSR2", "TST", "TTC1", "TTC19", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP4", "TUFM", "TUT1", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UACA", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBLCP1", "UBP1", "UBQLN4", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13C", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "WAPL", "WARS", "WARS2", "WASF2", "WASHC4", "WASHC5", "WBP11", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR33", "WDR34", "WDR36", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR70", "WDR77", "WDR82", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRN", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF131", "ZNF280C", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "AMOT", "ANKFY1", "AP1B1", "AP1S1", "APP", "ARFGAP1", "ARVCF", "ASCC2", "ATP6V0A1", "ATP6V0A2", "CHST14", "CLTA", "CUTA", "CYB5B", "CYP20A1", "DPY30", "DYM", "EFCAB14", "ERAP2", "ERGIC2", "EXT2", "FAM8A1", "FKBP14", "FLOT1", "G6PD", "GBF1", "GLB1", "GLG1", "GOLIM4", "GORASP2", "GPR107", "HAUS6", "HLA-A", "HMOX1", "HOOK3", "IGF2R", "ILVBL", "KDELR1", "KIAA0319L", "KIAA1147", "KIF11", "LAS1L", "LASP1", "MID1", "MPP1", "NAA25", "NAA40", "NAMPT", "NUCB1", "NUCB2", "NUDT9", "PPT1", "PSMG1", "RAB11B", "RAB1B", "SART1", "SCAMP1", "SCAMP2", "SCARB1", "SCPEP1", "SHCBP1", "SKA3", "SKIV2L", "SLC30A5", "SLC35F2", "SLC39A14", "SMYD4", "SNX1", "SNX2", "SPAG5", "SPNS1", "STX10", "STX5", "SURF4", "SYAP1", "SYNGR2", "TAP1", "TFRC", "TGOLN2", "TM9SF3", "TMEM165", "TMEM192", "TMEM87A", "TRMT6", "TSPAN3", "TSPAN6", "TUBB3", "UBAC1", "VPS26A", "YIF1A", "ZADH2", "ZNF622"]} \ No newline at end of file