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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Glycosaminoglycan degradation 0.8665189859171867 2.4986736602204416 0.0124659047760531 0.99947475309374 1.0 6 P15586,P16278,P54802 3
Sphingolipid metabolism integrated pathway 0.8397270399050432 2.3611243431218183 0.0182196204960196 0.9999844174731228 1.0 7 Q06136,P27544,Q96G23,O95470,Q13510 5
Sphingolipid metabolism overview 0.8397270399050432 2.3611243431218183 0.0182196204960196 0.9999844174731228 1.0 7 Q06136,P27544,Q96G23,O95470,Q13510 5
Proteoglycan biosynthesis 0.8049087071645833 2.2228179679435955 0.0262280769935963 0.9999998874712585 1.0 6 Q8NCH0,Q8WVQ1,Q93063,Q8TB61 4
Degradation pathway of sphingolipids including diseases 0.7784058060675474 2.1014797345851934 0.0355988751123388 0.9999999996664658 1.0 6 P17900,P16278,P06865 3
Striated muscle contraction pathway 0.7576555544507358 2.0053713176254586 0.0449233656693681 0.9999999999990384 1.0 6 P67936,P08670,P09493 3
Sphingolipid pathway 0.7606683352548314 1.981910974866078 0.0474892053958837 0.9999999999998096 1.0 8 Q06136,O95470,Q13510,P04062 4
Cellular proteostasis 0.7175834384742366 1.817104439575434 0.0692011231152287 1.0 1.0 6 P61758,Q9UHV9,Q9NQP4,O60925 4
Sphingolipid metabolism in senescence 0.7134725145162479 1.6863995716598417 0.0917188638966703 1.0 1.0 12 Q06136,Q13510,P16278,P04062 4
Regulation of apoptosis by parathyroid hormonerelated protein 0.864187709955312 1.6454772152622466 0.0998714375940501 1.0 1.0 3 Q9BXK5 1
Tlr4 signaling and tolerance 0.6789821898422644 1.6326526138267432 0.1025420788685353 1.0 1.0 6 Q15629 1
Oxidation by cytochrome p450 0.736529367430935 1.554140588351382 0.1201508853889352 1.0 1.0 5 Q6UW02,O43169 2
Mitochondrial complex iii assembly 0.6724854770097385 1.5272086166137788 0.126709144355908 1.0 1.0 10 P22695,Q6DKK2,Q9UDW1 3
Metabolism of spingolipids in er and golgi apparatus 0.8289162527368165 1.5064807173401438 0.1319438135211532 1.0 1.0 3 Q06136 1
Influence of laminopathies on wnt signaling 0.6679281839012843 1.487009787293428 0.1370122260081538 1.0 1.0 11 O60725 1
Cannabinoid receptor signaling 0.703822226486773 1.4792867197997306 0.1390637006803186 1.0 1.0 4 Q8NCG7 1
Kennedy pathway from sphingolipids 0.7121912749409829 1.4484958585116818 0.1474784234006518 1.0 1.0 5 P48651,O95470,P35790 3
Nad metabolism 0.8142269123990333 1.4483856526120262 0.147509225066297 1.0 1.0 3 P43490 1
Nad biosynthetic pathways 0.7079354283629483 1.429962456961987 0.1527277945563141 1.0 1.0 5 P43490 1
S1p receptor signal transduction 0.6324902223528068 1.3886134962425538 0.1649503111425969 1.0 1.0 7 P31751,Q13510 2
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6494079087977099 1.308434603470952 0.1907259422298952 1.0 1.0 16 O75844,O60725 2
Genes related to primary cilium development based on crispr 0.6462938296985953 1.2934739130104558 0.1958472008828726 1.0 1.0 16 Q10713,Q96EX3,O95684,Q9Y366 4
Irinotecan pathway 0.9181790218394348 1.2649600560213403 0.2058856470413763 1.0 1.0 2 P33527 1
Progeriaassociated lipodystrophy 0.617370304587886 1.2602593148300083 0.2075758316893514 1.0 1.0 10 O75844,O60725 2
Familial partial lipodystrophy fpld 0.6075771702865882 1.2486382099494795 0.2117974302315926 1.0 1.0 8 O60725 1
Inclusion body myositis 0.9138726545678284 1.2486078866906638 0.2118085263341389 1.0 1.0 2 P05067 1
Resistin as a regulator of inflammation 0.5919471917462331 1.20844158389095 0.2268774527272072 1.0 1.0 6 O14920,Q16539 2
Monoamine transport 0.8886496462626889 1.153180239698942 0.2488364124118449 1.0 1.0 2 O15127 1
Nephrotic syndrome 0.5960380674009074 1.1386604895976609 0.2548447881699798 1.0 1.0 11 Q14108 1
Neuroinflammation 0.6256138323481775 1.129123111853571 0.2588459028824401 1.0 1.0 4 P42345,Q16539 2
Hostpathogen interaction of human coronaviruses apoptosis 0.8800369117194711 1.120764801095082 0.2623879906277868 1.0 1.0 2 Q16539 1
Kisspeptinkisspeptin receptor system in the ovary 0.622750626506007 1.116314644877409 0.2642874750626656 1.0 1.0 4 Q15118 1
Mirnas involvement in the immune response in sepsis 0.6340210880575476 1.106651286750242 0.2684447242046928 1.0 1.0 5 Q16539 1
Ketogenesis and ketolysis 0.5697841088249593 1.099582909276866 0.271513891826421 1.0 1.0 6 P53985 1
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.5940744107329127 1.0940744418149588 0.2739223307286167 1.0 1.0 13 P55010,O75822,O15372,O00303,P60228 5
Signal transduction through il1r 0.5562129742704394 1.0330209632042702 0.3015940884641472 1.0 1.0 6 Q16539 1
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.6128841420059865 1.0143541848123911 0.310413777440343 1.0 1.0 5 P07099,P09601 2
Allograft rejection 0.5607517164372153 1.0022748741148062 0.3162108541974751 1.0 1.0 9 P10321,P01889,P08670 3
Vitamin a and carotenoid metabolism 0.5964834860365038 0.9992062397563256 0.3176947938003542 1.0 1.0 4 Q8WTV0 1
Zinc homeostasis 0.8366656413411351 0.9594338319340378 0.3373402383494084 1.0 1.0 2 Q8TAD4 1
Estrogen signaling pathway 0.5831271795318391 0.9400630162499066 0.347185237916237 1.0 1.0 4 Q16539 1
Amyotrophic lateral sclerosis als 0.5436216547791638 0.9365116351203074 0.3490098248251678 1.0 1.0 8 P07196,P07197 2
Adipogenesis 0.569025845580806 0.92268447403793 0.3561716592000814 1.0 1.0 16 O75844,P43490 2
Photodynamic therapyinduced ap1 survival signaling 0.5265254965473231 0.8710070734609486 0.3837502908981878 1.0 1.0 7 P07900,Q16539,Q07820 3
Cholesterol biosynthesis with skeletal dysplasias 0.5180093522051258 0.847017377029299 0.3969854357932418 1.0 1.0 6 Q15392 1
Ciliopathies 0.5666631748963339 0.8460501083696972 0.3975247914680491 1.0 1.0 20 Q9UBB4,Q9Y366,Q10713,O15078,Q9H0F7,Q96EX3,Q13049 7
Hijack of ubiquitination by sarscov2 0.5723522167487617 0.8391228981981141 0.4014003477888967 1.0 1.0 5 Q13617,Q8TBC4,Q15370,Q15369 4
Copper homeostasis 0.5649227544037629 0.8074079774356822 0.4194314723741326 1.0 1.0 5 P05067,Q8N668 2
1q211 copy number variation syndrome 0.5139525465826089 0.7937403887549878 0.4273465822984255 1.0 1.0 8 Q9NPH0,Q9Y624 2
Aryl hydrocarbon receptor pathway wp2873 0.5616910403445358 0.7936644221548597 0.4273908174901319 1.0 1.0 5 O00170,Q16543 2
Pathogenic escherichia coli infection 0.5542381999349947 0.788111746105458 0.4306313451290204 1.0 1.0 20 P04350,P07437,Q9BUF5,Q9BVA1 4
Mitochondrial complex iv assembly 0.5166104213174306 0.7732049970161116 0.4394010692957586 1.0 1.0 10 P14406 1
Tgfbeta receptor signaling 0.6396923076923053 0.7670222582055711 0.4430682818300147 1.0 1.0 3 P40763,P42224 2
Tgfbeta receptor signaling in skeletal dysplasias 0.6396923076923053 0.7670222582055711 0.4430682818300147 1.0 1.0 3 P40763,P42224 2
Heme biosynthesis 0.5406600711373564 0.7551795780524219 0.4501412403472487 1.0 1.0 4 P50336 1
Oxidative damage response 0.631906782483987 0.7381032304344469 0.460451720857159 1.0 1.0 3 O95429 1
Mitochondrial complex i assembly model oxphos system 0.5508606826604079 0.650884336139137 0.515121153572939 1.0 1.0 28 O43674,Q96CU9,Q8N183,O43676,O75380,O95168,Q9NPL8,O75306,Q9Y6M9,Q9P0J0,O95182 11
Metapathway biotransformation phase i and ii 0.5182956102868506 0.5944725634733456 0.5521960876549044 1.0 1.0 22 Q8NCH0,O15217,Q6UW02,Q16850,Q7LGA3 5
3q29 copy number variation syndrome 0.4803071738265004 0.5741324294348176 0.5658781898711793 1.0 1.0 12 O95684,Q96EX3 2
Complement and coagulation cascades 0.5853676573505259 0.5712912204611319 0.5678022520335742 1.0 1.0 3 P10909 1
Oxidative stress response 0.5072155421819617 0.568577315016705 0.5696430232556837 1.0 1.0 5 P09601 1
Hepatitis b infection 0.5080854817111874 0.5355342403782948 0.5922804872010277 1.0 1.0 23 Q15904,O14920,Q16539,P12004,P31946,Q9Y277,P31751,Q16531 8
Hostpathogen interaction of human coronaviruses interferon induction 0.457430629481623 0.5322627670322753 0.5945440159079902 1.0 1.0 8 Q16539 1
Intracellular trafficking proteins involved in cmt neuropathy 0.4641311403309653 0.5321180057162459 0.5946442673683059 1.0 1.0 10 Q15907,P07196 2
Congenital generalized lipodystrophy cgl 0.7090126115041613 0.5213438220420652 0.602127278709691 1.0 1.0 2 P31751 1
Pdgfrbeta pathway 0.4459501077918187 0.511288672453736 0.6091489356683975 1.0 1.0 6 P42224,P05771,P40763,P19174,P62993 5
Nanomaterial induced apoptosis 0.4774893796471385 0.4965034361381593 0.6195392636485915 1.0 1.0 4 Q9NR28 1
Relationship between inflammation cox2 and egfr 0.4746762771001126 0.4856703721963671 0.6272008932018311 1.0 1.0 4 Q9H7Z7 1
Serine metabolism 0.4382984083906602 0.4777338689398359 0.632839634957804 1.0 1.0 6 P00374 1
Id signaling pathway 0.6896339587819166 0.4628564785618629 0.6434672448946697 1.0 1.0 2 P06400 1
Mecp2 and associated rett syndrome 0.4876535798302293 0.4626714481392192 0.6435998868803372 1.0 1.0 22 P31943,P35637,Q05086,Q00013,P52597,P67809 6
Aryl hydrocarbon receptor pathway wp2586 0.4408490415962005 0.4598532029493558 0.6456215921304302 1.0 1.0 8 P06400,O00170,Q16543,P21359,P07900 5
Ferroptosis 0.4966818199871844 0.4463877115991447 0.6553172077532525 1.0 1.0 26 Q9NZ45,P09601,P45880,Q9UKU0,P02792 5
Hostpathogen interaction of human coronaviruses mapk signaling 0.430905902640431 0.4458559528185225 0.6557013013482895 1.0 1.0 6 Q16539 1
Ebsteinbarr virus lmp1 signaling 0.4289917593520259 0.4376939551199966 0.6616081520509678 1.0 1.0 6 O14920,P07900 2
Sting pathway in kawasakilike disease and covid19 0.5368466743791133 0.4124639666522661 0.6799993864746878 1.0 1.0 3 O14920 1
Apoptosis modulation by hsp70 0.44598337950139 0.3796948029116702 0.7041719784523364 1.0 1.0 4 P42575,O95831,P49327 3
Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.4349705731284549 0.3671439996055121 0.7135116085421676 1.0 1.0 13 O14920,Q15118,Q9UDY8,O95433 4
Ccl18 signaling pathway 0.4241227511513676 0.3629633764549649 0.7166322426881959 1.0 1.0 10 P08670,P07196 2
Supression of hmgb1 mediated inflammation by thbd 0.5184503547139436 0.357577959471952 0.7206591749488855 1.0 1.0 3 O14920 1
Transcription factors regulate mirnas related to cardiac hypertrophy 0.5099504850013723 0.3333752036310972 0.7388510782878392 1.0 1.0 3 P31751 1
Hostpathogen interaction of human coronaviruses autophagy 0.5080000000000156 0.3279300266473176 0.7429645699917371 1.0 1.0 3 P42345,Q9NT62 2
Novel intracellular components of rigilike receptor rlr pathway 0.4228395061728239 0.3196056913664687 0.7492672594221226 1.0 1.0 13 O43318,O14920,Q3LXA3,Q13546,Q16539,Q14258,O15111,O00571,Q92841,Q86UT6,Q13573,Q7Z434 12
Disorders of folate metabolism and transport 0.3978476488560611 0.2985375880986449 0.7652928921172193 1.0 1.0 7 P00374 1
Regulatory circuits of the stat3 signaling pathway 0.4025341367103111 0.2916852704890604 0.7705272721799994 1.0 1.0 9 P42345,Q8WTS6,Q16539,P16949 4
Vitamin d in inflammatory diseases 0.4178468287983961 0.2851926445894097 0.7754965552434014 1.0 1.0 4 Q16539 1
Autophagy 0.3887861983980367 0.2646835892425158 0.7912532206340384 1.0 1.0 7 Q99570,P42345,Q9Y4P8,P54646,P54619,Q9NT62 6
Synaptic signaling pathways associated with autism spectrum disorder 0.3983146370906856 0.2640829285492983 0.7917160181298404 1.0 1.0 10 P31751,P42345,P54619,Q05086 4
Tcell receptor tcr signaling pathway 0.4106575593741051 0.2284102514193373 0.8193273206006966 1.0 1.0 17 Q9UDY8,O14920,Q16539,P46108,P08670 5
Il17 signaling pathway 0.4085015326444127 0.2197693637360901 0.8260507805152244 1.0 1.0 5 O14920 1
Spinal cord injury 0.407362078048255 0.2171449919210372 0.8280953518753202 1.0 1.0 17 P08670,Q08722,P04083 3
Electron transport chain oxphos system in mitochondria 0.5056576746504722 0.1944080096684861 0.8458564187583948 1.0 1.0 51 O14949,P22695,P14406,O43676,P24539,O75964,P00846,O75306,Q9Y6M9,Q9UDW1,O95182 11
Exrna mechanism of action and biogenesis 0.4495384615384603 0.1855820746704783 0.8527725117028255 1.0 1.0 3 Q9UPY3,Q9HAV4 2
Wnt signaling pathway and pluripotency 0.3937287260818359 0.1825481992660389 0.8551525322077429 1.0 1.0 16 Q9H0H5,P30153,Q16537,P63151,P30154 5
Type i interferon induction and signaling during sarscov2 infection 0.4455384615384595 0.1774289733629755 0.8591714508902808 1.0 1.0 3 P42224,Q7Z434 2
Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.3810957582206166 0.172560564908013 0.8629968514494473 1.0 1.0 13 P43490 1
Hippoyap signaling pathway 0.4430769230769236 0.1725179962443989 0.8630303145090601 1.0 1.0 3 Q13188,Q13043 2
Mirna biogenesis 0.3779624499846156 0.1710041843460994 0.8642204754284615 1.0 1.0 4 Q9UPY3,Q9HAV4,Q8WYQ5 3
Myometrial relaxation and contraction pathways 0.3844886779167411 0.1440248505184663 0.8854808463396298 1.0 1.0 17 P63104,P78417,Q04917,P10644,P31946,P0DP25,P62258 7
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3696139488544531 0.1373295994376106 0.8907702751089355 1.0 1.0 13 P08670 1
Regulation of wnt bcatenin signaling by small molecule compounds 0.4236923076923093 0.1367008931635063 0.8912672235185732 1.0 1.0 3 P35222,P49841 2
Translation factors 0.4436919203050995 0.135095518394834 0.8925363534988873 1.0 1.0 37 O75821,P62495,P23588,P55010,Q15056,O75822,O15372,O00303,P60228,O75153,Q05639 11
Tolllike receptor signaling pathway 0.3567967928552638 0.1185078139473778 0.9056653040923212 1.0 1.0 11 O14920,Q16539 2
Modulators of tcr signaling and t cell activation 0.3584462787789122 0.1142393068435744 0.9090480934989776 1.0 1.0 12 O14920,O96000,P62993,Q9UDY8 4
Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.3541479670095462 0.1110610241597772 0.9115679556959472 1.0 1.0 11 O14920,Q16539 2
Primary focal segmental glomerulosclerosis fsgs 0.3763112600337591 0.1027078900876667 0.918194811381418 1.0 1.0 19 Q14108,P08670 2
Vitamin d receptor pathway 0.3690737002096265 0.1001141577888497 0.920253695513249 1.0 1.0 17 P09493,P08183,P49427,Q5VV42,Q96KA5,P04080 6
Nonalcoholic fatty liver disease 0.4707396035517855 0.1000175951118647 0.9203303566092762 1.0 1.0 50 O14949,P22695,O43674,P14406,O14920,O43676,O75380,O95168,Q96J02,Q86Y39,O75306,Q9Y6M9,Q9P0J0,Q9UDW1,O95182 15
Oxidative phosphorylation 0.4137880841110415 0.0946187008043263 0.9246176953836308 1.0 1.0 32 Q15904,O43674,P24539,O95168,O75964,P00846,O75787,O75306,Q9Y6M9,Q86Y39,O95182 11
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.3575023817547568 0.0900529710420403 0.9282451209795896 1.0 1.0 5 Q15118 1
Parkinubiquitin proteasomal system pathway 0.4210528855884464 0.0893545825883583 0.9288001168734497 1.0 1.0 35 P04350,P07437,Q9BUF5,Q9BVA1 4
Nucleotidebinding oligomerization domain nod pathway 0.3391044311609932 0.0875536022821993 0.9302314805090446 1.0 1.0 9 O14920,Q9P0J0 2
Nucleotide metabolism 0.3481579060264246 0.0864309633273786 0.931123833843535 1.0 1.0 12 P31350,P00374 2
Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.3270711425931595 0.0810328068591778 0.935415862184318 1.0 1.0 6 P12814,Q07157,P18206,P19174,P06756 5
Arachidonate epoxygenase epoxide hydrolase 0.4936942479237243 0.0798146911617239 0.9363846397446962 1.0 1.0 2 P20674 1
Initiation of transcription and translation elongation at the hiv1 ltr 0.3258392362180498 0.0779021195878156 0.9379059133498184 1.0 1.0 6 Q8WX92,O00267,Q92769,P18615,Q8IXH7 5
7oxoc and 7betahc pathways 0.3359495551217567 0.0714923476219189 0.943005914688559 1.0 1.0 10 P61916 1
Il9 signaling pathway 0.3477469514287893 0.0702013334592638 0.9440334129989028 1.0 1.0 5 P40763,P42224,P62993 3
Cardiac hypertrophic response 0.3353769849159951 0.0700783658719082 0.944131285894258 1.0 1.0 10 O14920,P31751,Q16539 3
Glycogen synthesis and degradation 0.3621887672321704 0.0662569911924249 0.9471732240002726 1.0 1.0 19 P0DP25,P63151,P30154,P52789 4
Epo receptor signaling 0.3204307315762263 0.0645449046376506 0.9485363528986952 1.0 1.0 6 P40763,Q15118,P62993 3
Regucalcin in proximal tubule epithelial kidney cells 0.3268698060941883 0.0643864074769687 0.9486625528312134 1.0 1.0 4 P42345,Q13283,Q8NE86 3
4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.3268698060941876 0.0643864074769673 0.9486625528312144 1.0 1.0 4 P06730,Q96KB5,P42345 3
Embryonic stem cell pluripotency pathways 0.3323684747354663 0.0627622627720261 0.9499558165419903 1.0 1.0 10 P42345,O00459,P40763,P62993,P61160,P31751 6
Rala downstream regulated genes 0.3195686613895236 0.0624744670099464 0.9501849945853118 1.0 1.0 6 P16989,Q8IYI6,P11233 3
Interleukin1 il1 structural pathway 0.3256385734242922 0.061817830363111 0.9507079040670948 1.0 1.0 8 Q16539 1
Sars coronavirus and innate immunity 0.4500153798831172 0.0493734224858114 0.9606217081065802 1.0 1.0 2 P42224 1
Folate metabolism 0.3387078021909551 0.0480122149666395 0.9617065076991198 1.0 1.0 14 Q8WTV0 1
Osx and mirnas in tooth development 0.4450938172869952 0.0469083851563707 0.9625862450642824 1.0 1.0 2 P35222 1
Type i collagen synthesis in the context of osteogenesis imperfecta 0.3336673083517584 0.0437782192466461 0.9650811889590138 1.0 1.0 13 Q32P28,O75718,O15460 3
Il7 signaling pathway 0.3269704433497442 0.0334190670486151 0.9733404048483868 1.0 1.0 5 P40763,P42224,P49841,O00459 4
Hedgehog signaling pathway wp4249 0.3249230769230686 0.0291301250231955 0.9767608096936332 1.0 1.0 3 P48729,Q9Y496 2
15q133 copy number variation syndrome 0.3246153846153808 0.0289636498474701 0.9768935816428466 1.0 1.0 3 Q9BXW9,P50454 2
Extracellular vesicles in the crosstalk of cardiac cells 0.374653952629958 0.0267006236723497 0.9786985156921904 1.0 1.0 2 P40763 1
Tca cycle nutrient use and invasiveness of ovarian cancer 0.326668717317746 0.0226997102714305 0.9818898069469432 1.0 1.0 2 P40763 1
Mammary gland development pathway involution stage 4 of 4 0.3011381113503519 0.0219320031617068 0.9825021960788732 1.0 1.0 2 P40763 1
Alzheimers disease and mirna effects 0.5265644253390028 0.0187472924037131 0.9850427009904948 1.0 1.0 80 Q9BUF5,P20618,P04350,Q92542,Q9NSK0,P21796,Q9BVA1,P49721,Q96IX5,P45880,Q13509,P0DP25,Q9Y277,P05067,P07437,O95197,P28072 17
Mirna regulation of prostate cancer signaling pathways 0.3016019716574313 0.0167240402160213 0.9866567685228556 1.0 1.0 7 P42345,P49841,Q8NCF5,P28482,P62993,P35222 6
Type ii diabetes mellitus 0.2893521535724953 0.0151963964755531 0.9878754965269856 1.0 1.0 4 O14920 1
Cancer immunotherapy by pd1 blockade 0.2704349270458834 0.0104087899322066 0.9916951371788874 1.0 1.0 3 P04439 1
Glucocorticoid receptor pathway 0.3012329487858451 0.004044160956098 0.996773235207481 1.0 1.0 9 P27105,P07900 2
Alzheimers disease 0.5166275171652771 0.0031611478232437 0.997477773158127 1.0 1.0 79 Q9BUF5,P20618,P04350,Q92542,Q9NSK0,P21796,Q9BVA1,P49721,P45880,Q13509,P0DP25,Q9Y277,P05067,P07437,O95197,P28072 16
Parkinsons disease pathway 0.2967713219453838 0.0018332132180564 0.998537308295924 1.0 1.0 8 Q16539 1