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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Cilium assembly 0.4696778063302116 2.7923131865387476 0.0052332676516335 0.999316371367614 0.3612680545623385 64 Q9H6D7,Q9H0F7,O43805,Q15154,Q9UPT5,P78371,A0AVF1,Q13509,O94927,O15078,Q96EX3,O95684,Q9Y366,Q9BUF5,O60645,O75935,P06493,Q13561,Q8NCM8,Q96FJ2,A6NIH7,P61163,P04350,P30153,Q92538,Q92973,Q10713,Q7Z4H7,Q96CS2 29
Ire1alpha activates chaperones 0.6238095094238547 2.7818205772578497 0.005405491521716 0.999462506548105 0.3612680545623385 24 Q9NWM8,P43307,O43731,Q9UBS4 4
Regulation of tp53 expression and degradation 0.7356986936631961 2.6871154668315396 0.0072072033575472 0.9999566868682128 0.3820739921597457 12 Q13362,P31751,P30153,P24941,P42771,P06493,P30154,P42345,Q13315,O96017 10
Copi dependent golgi to er retrograde traffic 0.4890190217620767 2.681281555560069 0.0073340780041311 0.9999637319822846 0.3820739921597457 52 Q8N6T3,P61923,O43731,Q9Y3B3,P24390,O15260,Q8NI77,Q13509,Q9NSK0,Q9BVK6,Q9NS87,P33176,O60333,Q9Y678,Q9P2W9,Q07866,P04350,Q92538,P52732 19
Golgi to er retrograde transport 0.4341195011278885 2.480431564923678 0.0131223450688939 0.9999999892416538 0.3836407111666756 75 Q8N6T3,Q15102,P61923,O43731,Q9Y3B3,P24390,O15260,Q8NI77,Q13509,Q9NSK0,Q9BVK6,Q9NS87,O75935,P33176,O60333,Q13561,Q9UJW0,Q9Y678,Q9P2W9,Q8TD16,Q96FJ2,Q07866,P04350,Q92538,P52732 25
Intra golgi and retrograde golgi to er traffic 0.3900500948833548 2.4742085322544347 0.0133531729338192 0.9999999922261876 0.3836407111666756 106 Q8N6T3,P61923,O60476,O00461,O43731,Q9Y3B3,P24390,O15260,Q13509,Q9NSK0,Q13190,O60499,Q8N2H4,O75935,P33176,Q16706,Q13561,Q9UJW0,Q9Y678,Q7Z6M1,Q9P2W9,Q8TD16,O95249,Q96FJ2,Q07866,P04350,Q92538 27
E2f mediated regulation of dna replication 0.7361189200048511 2.4719149915064125 0.013439146906764 0.9999999931124088 0.3836407111666756 11 P30153,Q14181,Q9Y619,P49643,P06493,P30154 6
Apc c cdc20 mediated degradation of cyclin b 0.6950663402274664 2.469405879530038 0.0135337615890331 0.9999999939714592 0.3836407111666756 12 Q13042,Q12834,P14635,Q9UJX4,P06493,Q9UJX3,Q9UJX2,Q9H1A4 8
Collagen formation 0.6865187678657673 2.4293834057409307 0.0151245286942338 0.9999999993592992 0.3849279775675934 13 P13674,O15460,Q32P28,O00469,O75718,P07237 6
Asparagine n linked glycosylation 0.3669768133968186 2.404670205505348 0.0161870663816714 0.9999999998569457 0.3849279775675934 115 P49257,Q8N6T3,P61923,O60476,Q9UBV2,O43731,Q9Y3B3,P24390,Q13509,Q13438,Q13190,Q9BT22,Q96PC5,Q2TAA5,O75935,Q16706,Q13561,Q9UJW0,Q9Y678,O95249,Q92734,P04350,Q92538,Q13724 24
Mitotic prometaphase 0.3885469566655058 2.348591544560099 0.018844566216412 0.9999999999966594 0.3849279775675934 102 Q9H6D7,P43034,Q12834,Q7Z5K2,Q7L7X3,O43805,Q15154,Q16537,Q9Y266,Q8NI77,Q13509,O94927,O15078,O95684,Q15005,Q9BSJ2,Q9BUF5,Q13362,P14635,O75935,Q96EA4,Q2NKX8,P06493,Q13561,Q96FJ2,Q29RF7,P67870,P61163,P04350,P30153,Q96BD8,Q7Z4H7,Q8WYP5,Q96CS2,P30154 35
Cyclin a b1 b2 associated events during g2 m transition 0.7327723989934416 2.327042185483368 0.0199630201015625 0.9999999999993148 0.3961233560152919 10 Q9Y570,P30153,Q99640,P24941,P06493,P63151,P30154 7
Unfolded protein response upr 0.501190863317852 2.2827583594547627 0.0224446060303855 0.9999999999999798 0.4101343080558462 40 Q92945,Q9UBS4,P43307,O43731,Q9NWM8,O95070 6
Collagen biosynthesis and modifying enzymes 0.6985884505421301 2.278103068676638 0.0227204374754648 0.9999999999999865 0.4101343080558462 11 P13674,O15460,Q32P28,O00469,O75718,P07237 6
Anchoring of the basal body to the plasma membrane 0.5171050441365661 2.25845801209663 0.0239171194762588 0.9999999999999976 0.4101343080558462 32 Q9H6D7,O43805,O94927,P04350,O15078,P30153,O75935,Q7Z4H7,O95684,Q13561,P06493 11
Heme degradation 0.9457374365847332 2.2318077472794022 0.0256276720798573 0.9999999999999998 0.4129373481037973 4 P30519,P09601 2
Transport to the golgi and subsequent modification 0.4066591084607908 2.188962321436701 0.0285995787112829 1.0 0.4271485465588386 79 P49257,Q8N6T3,P61923,O60476,O43731,Q9Y3B3,P24390,Q13509,Q9BVK6,Q13190,O95487,Q96PC5,O75935,O95486,Q16706,Q13561,Q9UJW0,Q9Y678,O95249,Q96FJ2,Q92734,P04350,Q92538 23
Recruitment of mitotic centrosome proteins and complexes 0.499653739428535 2.159487962246009 0.0308123302378282 1.0 0.4412198628901386 35 Q9H6D7,O43805,O94927,P04350,O15078,P30153,O75935,Q7Z4H7,O95684,Q13561,Q9BSJ2,P06493 12
Negative regulation of mapk pathway 0.6326837922152573 2.124061197280345 0.0336650266241886 1.0 0.4629774453564166 12 Q13362,Q7Z569,P30153,Q99956,Q16537,P28482,Q6UWU4,P30154 8
Recruitment of numa to mitotic centrosomes 0.4870006513177141 2.109805222608096 0.034875136441878 1.0 0.469495398624953 38 Q9H6D7,Q13509,O43805,O94927,P04350,O15078,P30153,O75935,Q7Z4H7,O95684,Q13561,Q9BSJ2,P06493 13
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.7721520181384274 2.0838974479464913 0.037169496546203 1.0 0.469495398624953 7 Q14181,P30154,P30153,P49643 4
Metabolism of porphyrins 0.7391640828844113 2.0807924591398304 0.0374529066912268 1.0 0.469495398624953 8 P30519,P09601,P50336 3
Mitotic g2 g2 m phases 0.3860963235627019 2.073486298115537 0.0381270449808408 1.0 0.469495398624953 90 Q9H6D7,O43805,P25787,Q13509,Q92530,O94927,O15078,O95684,Q9BSJ2,P49721,O75935,P06493,Q13561,Q9Y570,P04350,Q99640,Q9UL46,P30153,Q7Z4H7,P30154 20
Copi mediated anterograde transport 0.4116981953382 2.046365452879824 0.0407204284006534 1.0 0.469495398624953 55 Q9Y3B3,P24390,Q8N6T3,Q13509,P61923,P04350,O75935,Q92538,Q13190,O43731,Q13561,Q9Y678,Q9UJW0,O95249 14
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6772183429235007 2.0451618033490417 0.040838908845513 1.0 0.469495398624953 10 Q13042,Q12834,Q9UJX4,Q9UJX2,Q9UJX3,Q9H1A4 6
Regulation of plk1 activity at g2 m transition 0.4789997068553021 2.0016058335618205 0.0453271411138844 1.0 0.4824448080784625 36 Q9H6D7,O43805,O94927,P04350,O15078,P30153,O75935,Q7Z4H7,O95684,Q13561,P06493 11
Aurka activation by tpx2 0.48137772942451 1.9908409402739953 0.0464983768455531 1.0 0.4824448080784625 34 Q9H6D7,O43805,O94927,P04350,O15078,P30153,O75935,Q7Z4H7,O95684,Q13561,P06493 11
Phosphorylation of the apc c 0.6086402370371625 1.9873812421194923 0.0468801647692918 1.0 0.4824448080784625 12 Q13042,P14635,Q9UJX4,P06493,Q9UJX3,Q9UJX2,Q9H1A4 7
Separation of sister chromatids 0.3437948375654584 1.9777362634620417 0.0479584670431492 1.0 0.4827123965430018 113 P20618,P43034,Q12834,Q7Z5K2,Q7L7X3,Q14738,P25787,Q16537,Q9Y266,Q9UJX3,P61289,Q8NI77,Q13509,P63167,Q06323,Q92530,Q15005,Q9BUF5,Q13362,Q13042,Q14674,P49721,Q9UJX4,Q96EA4,Q2NKX8,Q96FJ2,Q29RF7,O00487,P04350,Q96DE5,Q9UL46,O00231,P30153,Q96BD8,Q9UJX2,Q7Z460,Q8WYP5,Q8NFH4,P30154,Q9H1A4 40
Phosphorylation of emi1 0.8779085126023535 1.9641499153329236 0.049512709058592 1.0 0.4932802258993279 4 Q12834 1
Er to golgi anterograde transport 0.3904187442459411 1.9475515324684585 0.0514686479426822 1.0 0.5034503661435609 75 P49257,Q8N6T3,P61923,O43731,Q9Y3B3,P24390,Q13509,Q9BVK6,Q13190,O95487,Q96PC5,O75935,O95486,Q13561,Q9UJW0,Q9Y678,O95249,Q96FJ2,Q92734,P04350,Q92538 21
Phase i functionalization of compounds 0.5979719810452019 1.9371182825508697 0.052730886263453 1.0 0.5086333404162239 15 Q6QHF9,O43169,Q16850,P07099 4
Signaling by hedgehog 0.3949989310326355 1.920462124773198 0.0547995528751632 1.0 0.5213464311205599 57 Q6PHR2,Q13509,Q92530,P25787,P49721,P04350,Q9UL46,Q13438,Q9UBV2,Q9Y366 10
Diseases of mitotic cell cycle 0.594470446775362 1.910390955357924 0.0560828945247087 1.0 0.5260092753115285 14 Q13042,P11802,P06400,Q9UJX4,P24941,Q9UJX2,Q9UJX3,Q9H1A4 8
G1 s specific transcription 0.6709066574116249 1.90249654169088 0.0571062705432035 1.0 0.5260092753115285 9 P06493,Q9Y619,P00374 3
Slc mediated transmembrane transport 0.5025153186272654 1.8829871545017496 0.0597021088043847 1.0 0.5260092753115285 23 Q15043,Q8TAD4,P08195,Q70HW3 4
Transport of inorganic cations anions and amino acids oligopeptides 0.6432263433466208 1.8684256764946048 0.0617027608817484 1.0 0.5260092753115285 10 Q9UBX3,P08195,Q9Y6M7,Q70HW3 4
Organelle biogenesis and maintenance 0.3598145944833713 1.8529557729953297 0.0638886980327781 1.0 0.534586756430897 98 Q9H6D7,P43034,Q9H0F7,O43805,P54619,Q15154,Q9UPT5,P78371,A0AVF1,Q13509,P63167,O94927,O15078,Q6UXV4,Q5XKP0,Q96EX3,O95684,Q9Y366,Q9BUF5,P00846,O60645,Q13505,O75935,Q16891,Q16539,O00411,P06493,Q8NCM8,Q13561,Q96FJ2,A6NIH7,O75964,P61163,P04350,P30153,Q92538,Q92973,Q10713,Q7Z4H7,P54646,Q96CS2 41
Striated muscle contraction 0.7410845331221984 1.838809545005842 0.0659432038469478 1.0 0.5356439189673132 6 P09493,P06753,P08670 3
Mitotic spindle checkpoint 0.3855801187998525 1.824951919945935 0.068008285185255 1.0 0.5445520716098835 64 P43034,Q12834,Q7L7X3,Q14738,Q16537,Q9Y266,Q9UJX3,Q8NI77,P63167,Q15005,Q13362,Q13042,Q9UJX4,Q96EA4,Q2NKX8,Q96FJ2,Q96DE5,P30153,Q96BD8,Q7Z460,Q9UJX2,Q8WYP5,Q8NFH4,P30154,Q9HBM1,Q9H1A4 26
Peptide hormone metabolism 0.5789718378638976 1.8234748131516112 0.0682315084014777 1.0 0.5445520716098835 15 O60645,Q96HE7,Q99626,P33176,Q8TAD4,Q96KP1,O00471,Q15005,O75787,Q9UPT5 10
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5795780343780599 1.819618649960693 0.0688170995293711 1.0 0.5445520716098835 12 Q13042,Q12834,Q9UJX4,Q9UJX2,Q9UJX3,Q9H1A4 6
Apc cdc20 mediated degradation of nek2a 0.5795780343780599 1.819618649960693 0.0688170995293711 1.0 0.5445520716098835 12 Q13042,Q12834,Q9UJX4,Q9UJX2,Q9UJX3,Q9H1A4 6
Resolution of sister chromatid cohesion 0.3832529838512545 1.8184189871750067 0.069000118504924 1.0 0.5445520716098835 69 P43034,Q12834,Q7Z5K2,Q7L7X3,Q14738,Q16537,Q9Y266,Q8NI77,Q13509,P63167,Q15005,Q9BUF5,Q13362,P14635,Q96EA4,Q2NKX8,P06493,Q96FJ2,Q29RF7,P04350,P30153,Q96BD8,Q7Z460,Q8WYP5,Q8NFH4,P30154,Q9HBM1 27
Platelet sensitization by ldl 0.7077247470855699 1.789270929589736 0.0735711934172247 1.0 0.5671578013011717 7 Q13362,P30153,Q16539,Q16537,P30154 5
Intraflagellar transport 0.5723434399843527 1.779140038700752 0.0752168058913527 1.0 0.5688374690331527 14 A0AVF1,Q13509,P04350,Q92973,Q96EX3,Q8NCM8,Q9Y366,Q96FJ2,Q9BUF5 9
Dna replication initiation 0.7276241731396236 1.7783063158659929 0.075353559612743 1.0 0.5688374690331527 6 Q14181,P56282 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.6027988487487581 1.7640312122327884 0.0777267243868511 1.0 0.5765698982440337 11 Q13042,P06400,Q9UJX4,Q9UJX2,Q9UJX3,Q9H1A4 6
Interleukin 4 and interleukin 13 signaling 0.5656020665422509 1.737998044390783 0.0822111583620064 1.0 0.580335191037544 12 P09601,Q07820,P08670 3
Apc c mediated degradation of cell cycle proteins 0.3772491549703169 1.7147476643065245 0.0863915005861375 1.0 0.5906992082422257 58 P20618,Q12834,P25787,P24941,Q9UJX3,P61289,Q06323,Q92530,Q13042,P49721,P14635,Q9UJX4,P06493,O00487,P06400,Q96DE5,Q9UL46,Q9UJX2,Q9H1A4 19
Heparan sulfate heparin hs gag metabolism 0.7581450913758261 1.7127694675371914 0.0867549593098733 1.0 0.5906992082422257 5 Q7LGA3 1
Zinc transporters 0.9458628114426344 1.701272175000081 0.088891890385069 1.0 0.596477467366478 2 Q8TAD4 1
Metal ion slc transporters 0.9458628114426344 1.701272175000081 0.088891890385069 1.0 0.596477467366478 2 Q8TAD4 1
Mitochondrial protein import 0.445560411965114 1.6755644201312558 0.0938235428994396 1.0 0.6205757194634363 33 Q9NS69,Q99595,Q9Y584,Q13505 4
Mastl facilitates mitotic progression 0.7473868029537778 1.6662220925770277 0.0956691872364308 1.0 0.6260545314728126 5 P30154,P06493 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3949830373962372 1.6504476893125402 0.0988514040537373 1.0 0.6386260475843778 51 Q13042,Q12834,P06400,Q92530,P25787,P49721,Q9UJX4,Q9UL46,Q9UJX2,Q9UJX3 10
Synthesis of pc 0.7383390577894378 1.626955907895935 0.1037464626162898 1.0 0.6492256737694598 5 P35790 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.6445095842808 1.6242815295800193 0.1043157374074601 1.0 0.6492256737694598 8 Q13362,P30154,P30153,Q16537 4
Beta catenin phosphorylation cascade 0.6445095842808 1.6242815295800193 0.1043157374074601 1.0 0.6492256737694598 8 Q13362,P30154,P30153,Q16537 4
Signaling by ctnnb1 phospho site mutants 0.6445095842808 1.6242815295800193 0.1043157374074601 1.0 0.6492256737694598 8 Q13362,P30154,P30153,Q16537 4
Hur elavl1 binds and stabilizes mrna 0.791918606457988 1.6155955252355052 0.1061817920237517 1.0 0.6543636137230472 4 Q01105 1
Visual phototransduction 0.6914708825885676 1.6142669773671026 0.1064695296626412 1.0 0.6543636137230472 6 P49356,P53582 2
Diseases associated with n glycosylation of proteins 0.6885603472499461 1.6009711625328529 0.1093833064139311 1.0 0.6663746167059226 6 Q13724,Q2TAA5 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5371569368601085 1.5676600204734743 0.1169604966435509 1.0 0.6977776472388515 13 P09601,Q13190,P51648 3
Oncogene induced senescence 0.6583675388041165 1.5581321451042551 0.1192019260110117 1.0 0.6977776472388515 7 Q9HCE1,P11802,P28482,P06400 4
Metabolism of cofactors 0.6778136015740518 1.5517734467338151 0.1207164415854205 1.0 0.6977776472388515 6 O75874 1
Cyclin d associated events in g1 0.5335249186415398 1.548576731737371 0.1214835029767522 1.0 0.6977776472388515 12 P06400,P30153,P24941,P42771,P11802,P30154 6
Kinesins 0.4573050017142084 1.5450233022829034 0.1223406270577167 1.0 0.6977776472388515 23 Q07866,Q8NI77,Q13509,P04350,Q9NSK0,P33176,O60333,P52732,Q9NS87 9
Regulation of tp53 activity 0.3763264315616826 1.5407319832306472 0.1233820293401188 1.0 0.6977776472388515 53 Q8TBX8,P24941,P54619,P42345,Q13315,Q14191,Q9UQ84,Q13362,P31751,Q92804,Q16539,O95696,P06493,P67870,O95983,P30153,P42771,P54646,P30154,Q8WXE1,O96017 21
Platelet homeostasis 0.5617564788329331 1.5360115334713411 0.1245355516803097 1.0 0.7003234060078956 11 Q13362,P16615,P30153,Q16539,P30626,Q16537,P30154 7
Signaling by wnt in cancer 0.5763602169556373 1.512285659472734 0.1304612076194153 1.0 0.7098902689225934 10 Q13362,P30154,P30153,Q16537 4
Golgi cisternae pericentriolar stack reorganization 0.5761131265209825 1.5109517232918863 0.1308007512976932 1.0 0.7098902689225934 10 Q9H8Y8 1
Activation of ampk downstream of nmdars 0.6483658900790654 1.5108114075513306 0.1308365074472166 1.0 0.7098902689225934 7 P04350,P54646,Q13509,P54619 4
Response to elevated platelet cytosolic ca2 0.4249533556488431 1.5071376308019444 0.1317753828834647 1.0 0.7122023611872859 34 Q8NBX0,P07602,Q8NBM8,Q9NTK5,O94919,O43852 6
Transport of bile salts and organic acids metal ions and amine compounds 0.764574069453753 1.5030334103082288 0.1328304286602202 1.0 0.7129940072660678 4 Q8TAD4 1
Interleukin 12 family signaling 0.4303549722475169 1.4981774847526934 0.1340871437511119 1.0 0.7163347795011328 29 O14979,P07237,Q9UL46,O00170,Q00169,P22626,P52597,Q13126 8
Rhobtb1 gtpase cycle 0.4588751998566509 1.4867478684399558 0.1370814148125017 1.0 0.721393168013033 20 P38159,O75116,Q8N684,P62995,P08670,O43396 6
Signaling by ptk6 0.5529568162177476 1.4866342209301726 0.1371114444603605 1.0 0.721393168013033 11 P46108,Q14185,P24941,P23246,Q07666,P11802 6
Complex i biogenesis 0.4242129892280908 1.4798733463411926 0.1389070499735643 1.0 0.721651105350657 31 Q9Y6M9,Q9NPL8,Q8TB37,O95182,O43676,Q8N183,O95168 7
Signaling by interleukins 0.3302916155861735 1.464025803033843 0.1431868983029967 1.0 0.721651105350657 100 P25787,O14979,Q07820,P22626,P46108,Q92530,P09601,O00170,Q00169,P07237,P52597,P42224,P49721,P08670,Q13126,P30153,Q9UL46,P40222,P30154 19
Signaling by notch3 0.6587133779462429 1.463962151260389 0.1432042900651073 1.0 0.721651105350657 6 P67809,Q13573,P42224 3
Raf independent mapk1 3 activation 0.7537878219483058 1.4584694434407492 0.1447111916808285 1.0 0.721651105350657 4 P06493,P28482 2
Ptk6 regulates proteins involved in rna processing 0.8861888649646266 1.4581767631392424 0.1447918269717862 1.0 0.721651105350657 2 P23246 1
Rho gtpases activate iqgaps 0.5462460091510892 1.4488806925715807 0.1473709039225914 1.0 0.721651105350657 11 Q86VI3,Q13576,Q13509,P04350 4
E2f enabled inhibition of pre replication complex formation 0.7503134648460668 1.44409889561198 0.1487111587085685 1.0 0.721651105350657 4 P06493 1
Abc family proteins mediated transport 0.3630466227339913 1.440881849654474 0.1496180646019447 1.0 0.721651105350657 54 Q92530,P25787,P49721,Q9UL46,Q9UBV2,Q9NUT2,P33527 7
Signaling by vegf 0.4195482443790398 1.440211775240099 0.1498074927677697 1.0 0.721651105350657 31 O43865,P46108,O75116,Q14185,Q7L576,Q96F07,Q9UQB8,Q13153 8
Interleukin 12 signaling 0.4324032846010993 1.4383813639376417 0.1503258773820504 1.0 0.721651105350657 26 O14979,Q9UL46,O00170,Q00169,P22626,P52597,Q13126 7
Rnd2 gtpase cycle 0.4652228509717449 1.4345551400400842 0.151413905689403 1.0 0.7226249356851279 19 P38159,Q07960,P51648,Q9Y266,Q8TAA9,O43396,Q07065 7
Biological oxidations 0.4021609633555884 1.4255665175924672 0.1539935068126694 1.0 0.7226249356851279 42 O43169,Q6QHF9,Q16850,Q99707,P07099,O15217 6
Condensation of prometaphase chromosomes 0.5751059325813546 1.4096686331120385 0.1586375507897564 1.0 0.7394213357280927 9 Q15003,P14635,P67870,P06493 4
Copi independent golgi to er retrograde traffic 0.4253849909699046 1.4051552604035558 0.1599751147091677 1.0 0.7417643952255806 27 P43034,P63167,Q13509,Q15102,P61163,P04350,O75935,Q13561,Q9UJW0,Q8TD16,Q96FJ2,Q9BUF5 12
Trna modification in the nucleus and cytosol 0.509351042617626 1.397906399328009 0.1621411767442144 1.0 0.7417643952255806 14 Q9UJA5,Q5VV42,P07814,Q2VPK5,Q9UET6,Q6YHU6 6
Tp53 regulates transcription of cell cycle genes 0.5088241359706231 1.3946801357221517 0.1631123176608233 1.0 0.7417643952255806 14 O95628 1
Mitotic g1 phase and g1 s transition 0.3465621072951301 1.394641207908199 0.1631240620834688 1.0 0.7417643952255806 75 P20618,P25787,P24941,Q9Y619,P56282,P49643,P63151,P61289,Q06323,Q92530,P04818,P31350,P11802,P63208,P31751,P00374,P49736,P49721,P14635,Q14181,P06493,P33991,O00487,P06400,O00231,Q9UL46,P30153,P42771,P30154,Q14566 30
Insulin processing 0.5538156308566481 1.390159285419983 0.1644805138441172 1.0 0.7417643952255806 10 O60645,Q96HE7,P33176,Q8TAD4,Q96KP1,O00471,Q9UPT5 7
Er quality control compartment erqc 0.876974481007519 1.3873881550685383 0.1653234348996324 1.0 0.7431529161022311 3 Q9UBV2 1
Prolonged erk activation events 0.6821860228076511 1.3812471883554964 0.1672029701780966 1.0 0.7491771792818587 5 P28482,P46108 2
Ctla4 inhibitory signaling 0.5950629360554169 1.3789836051597228 0.1678998088392713 1.0 0.7498804967130158 8 Q13362,P31751,P30153,Q16537,P30154 5
Hs gag biosynthesis 0.86281144263304 1.3628334993870517 0.172934990845988 1.0 0.7649894977231765 2 Q7LGA3 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4294655722110267 1.3580106427501648 0.1744603071208443 1.0 0.7690909286345847 24 O14979,Q9UL46,O00170,Q00169,P52597,Q13126 6
N glycan trimming in the er and calnexin calreticulin cycle 0.4980091504305789 1.3283681799643496 0.184056506057979 1.0 0.7927184868544349 14 Q13724,Q9UBV2 2
Signaling by fgfr1 in disease 0.5246509784583974 1.326915010323809 0.1845367984269776 1.0 0.7927184868544349 11 P42224,P19174,O95429,O95684,Q92614 5
Mitotic metaphase and anaphase 0.3141765722811829 1.3207332138200436 0.1865903353429074 1.0 0.7927184868544349 149 P20618,P43034,Q12834,Q7Z5K2,Q7L7X3,Q14738,P25787,Q16537,Q9Y266,Q9UJX3,Q99986,P63151,Q8NFH5,P61289,Q8NI77,Q13509,P63167,Q92530,P42166,Q15005,Q86XL3,Q86Y07,Q9BUF5,Q13362,Q13042,Q14674,P49721,P14635,Q9UQN3,P42167,Q9UJX4,Q96EA4,Q2NKX8,P06493,Q96FJ2,Q29RF7,Q9BTX1,P04350,Q96DE5,Q9UL46,P30153,Q92973,Q96BD8,Q9UJX2,Q8WYP5,P30154,Q9H1A4 47
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7195155185413643 1.3164698305024394 0.188016398015244 1.0 0.7927184868544349 4 Q99626 1
Incretin synthesis secretion and inactivation 0.7195155185413643 1.3164698305024394 0.188016398015244 1.0 0.7927184868544349 4 Q99626 1
Iron uptake and transport 0.4478628820424241 1.3122415488705377 0.1894386470226434 1.0 0.7927184868544349 19 P30519,P09601,Q93050 3
Telomere c strand synthesis initiation 0.623575032860878 1.3014575522423322 0.1931018849829628 1.0 0.7938717989696608 6 Q14181 1
Suppression of apoptosis 0.8458935712088624 1.293947914285742 0.1956834125891804 1.0 0.7964672531489455 2 P23246 1
Cargo trafficking to the periciliary membrane 0.4265931725985779 1.2510141606989438 0.2109293110729959 1.0 0.8279267424499869 20 P78371,Q9H0F7,O60645,Q92538,Q10713,Q96KP1,O00471,Q9UPT5,A6NIH7 9
Initiation of nuclear envelope ne reformation 0.4503073260110733 1.2435104233050314 0.2136798023834494 1.0 0.8290537584095287 18 P14635,P30153,Q99986,P42166,P06493,P63151,Q86XL3,Q86Y07 8
Signaling by mapk mutants 0.8286681021224244 1.2240015321660025 0.2209516495405616 1.0 0.8411664306951127 2 P28482 1
Erk mapk targets 0.563525460254386 1.2210869632360584 0.2220530951776844 1.0 0.8411664306951127 8 P30154,P30153,P28482,Q16539 4
Mapk targets nuclear events mediated by map kinases 0.563525460254386 1.2210869632360584 0.2220530951776844 1.0 0.8411664306951127 8 P30154,P30153,P28482,Q16539 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6965220067713168 1.2210704486966544 0.2220593473765051 1.0 0.8411664306951127 4 P24941,P11802,P06400 3
Sphingolipid de novo biosynthesis 0.5225501556821697 1.2197685204737745 0.2225526380075426 1.0 0.8411664306951127 10 Q06136,Q96G23,P51648,O95470 4
Small interfering rna sirna biogenesis 0.6940597106802119 1.2108586150613163 0.225949595978306 1.0 0.8411664306951127 4 O75569,Q15631,Q9UPY3 3
Pexophagy 0.8243617348508241 1.2065563394928358 0.2276030496004537 1.0 0.8411664306951127 2 P50542 1
Nuclear events kinase and transcription factor activation 0.5033968764653616 1.2063964913617489 0.2276646482631679 1.0 0.8411664306951127 11 P50570,P30153,Q16539,P28482,P30154 5
Transcriptional regulation by ventx 0.4775010404701701 1.2022869821700255 0.2292523587897497 1.0 0.8411664306951127 14 Q13042,Q9HCE1,Q9UJX4,P42771,Q9UJX2,Q9UJX3,Q9H1A4 7
Bbsome mediated cargo targeting to cilium 0.557954319844391 1.193145075942844 0.2328125606295625 1.0 0.8411664306951127 8 Q9H0F7 1
Hedgehog ligand biogenesis 0.3816023818086207 1.1928373716901055 0.2329330707482917 1.0 0.8411664306951127 40 Q92530,P25787,P49721,Q9UL46,Q9UBV2 5
Gap junction assembly 0.6894310263203403 1.191667496379066 0.2333916477354436 1.0 0.8411664306951127 4 P04350,Q13509 2
Transport of connexons to the plasma membrane 0.6894310263203403 1.191667496379066 0.2333916477354436 1.0 0.8411664306951127 4 P04350,Q13509 2
Leishmania infection 0.3857376988463991 1.1896756213406583 0.2341739107660951 1.0 0.8411664306951127 37 O43865,P46108,P09601,Q14185,Q96F07,Q9UQB8 6
Rho gtpases activate formins 0.3323317782160348 1.1877319606814112 0.2349390277733332 1.0 0.8411664306951127 68 P43034,Q12834,Q7L7X3,Q14738,Q16537,Q9Y266,Q8NI77,Q13509,P63167,Q15005,Q9BUF5,Q13362,Q96EA4,Q2NKX8,Q96FJ2,P04350,P30153,Q96BD8,Q7Z460,Q8WYP5,Q8NFH4,P30154,Q9HBM1 23
Pre notch processing in golgi 0.637430825386281 1.1840215716954026 0.236404523766754 1.0 0.8419638038769779 5 Q9UBV2 1
Maturation of sars cov 2 spike protein 0.5152802198066673 1.180065767817193 0.2379740583388225 1.0 0.8432120217707201 10 P04844,Q13724,Q16706,P26572,Q14697 5
Role of phospholipids in phagocytosis 0.6865946453906193 1.1799116621921384 0.2380353510056552 1.0 0.8432120217707201 4 O43865,Q8IV08 2
Rho gtpases activate ktn1 0.5784066879786081 1.1769248838151187 0.2392254890682597 1.0 0.8432120217707201 7 Q9NSK0,P33176 2
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.685532666137141 1.1755110580278132 0.2397903157663314 1.0 0.8432120217707201 4 Q14185 1
Activation of nima kinases nek9 nek6 nek7 0.6823638042474636 1.1623833860472028 0.2450797687873014 1.0 0.8516977932038988 4 P14635,P53350,P06493 3
Pink1 prkn mediated mitophagy 0.551733312890038 1.1619419521720764 0.2452590446677789 1.0 0.8516977932038988 8 Q9NS69 1
Switching of origins to a post replicative state 0.3300066804834947 1.1571563818012929 0.2472084747383576 1.0 0.8562907017745105 57 P20618,P25787,P24941,Q9Y619,O43242,Q9UJX3,Q13200,P33992,P61289,Q06323,Q92530,P63208,P62333,Q13042,P49736,P49721,Q9UJX4,P33991,Q99436,O00487,O00231,Q9UL46,Q96DE5,P62195,P28074,P60900,Q9UJX2,Q14566,Q9H1A4 29
Fgfr1 mutant receptor activation 0.5106812870285004 1.1549485152869772 0.2481115103899354 1.0 0.8572808157502992 10 O95429,P42224,O95684 3
Intra golgi traffic 0.4239222230210695 1.1429957332138392 0.2530403625957342 1.0 0.8648481439291702 19 Q16706,O95249,O60476,Q13190 4
Runx3 regulates p14 arf 0.8077514610888972 1.1394689831608362 0.2545075979789706 1.0 0.8664486607666425 2 P25440 1
Unwinding of dna 0.546426896592165 1.1353305454124156 0.2562368485283455 1.0 0.869128042388874 8 P49736,Q9BRT9,Q14566 3
Traf6 mediated nf kb activation 0.5876193409300935 1.1345925539323465 0.2565460744272414 1.0 0.869128042388874 6 O15111,Q7Z434,P05067,P09429,Q14258 5
Cobalamin cbl vitamin b12 transport and metabolism 0.6214072369536057 1.1134549717171742 0.2655130768776785 1.0 0.880563133713568 5 Q99707 1
Ras processing 0.6694606506624465 1.108995098852977 0.2674322963187776 1.0 0.880563133713568 4 O60725,P49356 2
Carboxyterminal post translational modifications of tubulin 0.6202916582534949 1.108547685727859 0.2676253569004148 1.0 0.880563133713568 5 P04350,Q13509 2
Defective cftr causes cystic fibrosis 0.3688894013265353 1.1077668717285605 0.267962510745678 1.0 0.880563133713568 42 Q92530,P25787,P49721,Q9UL46,Q9UBV2 5
Abc transporter disorders 0.3688894013265353 1.1077668717285605 0.267962510745678 1.0 0.880563133713568 42 Q92530,P25787,P49721,Q9UL46,Q9UBV2 5
Ptk6 regulates cell cycle 0.7997539218701949 1.1073032146045234 0.2681628549754062 1.0 0.880563133713568 2 P11802 1
Notch4 intracellular domain regulates transcription 0.7957551522608519 1.0912588889237895 0.2751589820037012 1.0 0.8915989998226158 2 Q04721 1
N glycan trimming and elongation in the cis golgi 0.7945247616118251 1.086327705703244 0.2773340335779548 1.0 0.8915989998226158 2 O60476 1
Notch2 activation and transmission of signal to the nucleus 0.7920639803137591 1.0764734541183216 0.2817155668304913 1.0 0.8915989998226158 2 Q04721 1
Signaling by notch2 0.7920639803137591 1.0764734541183216 0.2817155668304913 1.0 0.8915989998226158 2 Q04721 1
Calnexin calreticulin cycle 0.5343874687634382 1.074998315742973 0.282375482393971 1.0 0.8915989998226158 8 Q9UBV2,Q13438 2
S phase 0.3101611886662544 1.0702322325175695 0.2845147892285653 1.0 0.894097380630039 93 Q7Z5K2,P25787,P24941,Q9Y619,P56282,P49643,Q9UJX3,P61289,Q92530,P11802,Q9Y2S7,Q13042,P31751,P49721,Q9BRT9,Q9UJX4,Q14181,Q29RF7,P06400,Q9UL46,Q9UJX2,Q14566,Q9H1A4 23
G2 m dna replication checkpoint 0.7923558371515993 1.0666392402547071 0.2861347737861455 1.0 0.8971584667922259 3 P06493 1
Aquaporin mediated transport 0.6506809882742184 1.0315652267296065 0.3022758373284657 1.0 0.9187333436526016 4 Q99797 1
Fcgamma receptor fcgr dependent phagocytosis 0.3710049874866466 1.026512563296197 0.3046500448415834 1.0 0.9223172502740364 32 O43865,P46108,Q14185,Q7L576,Q96F07,Q9UQB8,Q8IV08,Q13153 8
Activation of the ap 1 family of transcription factors 0.7791448784989279 1.024931060325633 0.3053957176849424 1.0 0.9223172502740364 2 P28482 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.779384615384618 1.0180539968028792 0.3086522958037432 1.0 0.9279611230982668 3 P54646,P54619 2
Activation of nmda receptors and postsynaptic events 0.3945798931128 1.016565967577464 0.3093599508177453 1.0 0.928079852453236 20 P52292,Q13509,P04350,P54619,P54646,P28482,P07196 7
Mitophagy 0.4444991424306065 1.013837378597756 0.310660356210803 1.0 0.929972488743115 12 Q9NS69,Q15388,Q8N4H5 3
Sting mediated induction of host immune responses 0.5602094240837807 1.0077127075969128 0.3135924026662455 1.0 0.933606655398549 6 P19474,P49959,P13010,P12956,Q9UJV9 5
Estrogen dependent nuclear events downstream of esr membrane signaling 0.7741753885135803 0.9986180511759882 0.3179797522906238 1.0 0.933606655398549 3 P31751 1
Synthesis of pe 0.7722524861462501 0.9914556532478368 0.3214631364771132 1.0 0.9343862738814418 3 P35790 1
Regulation of signaling by cbl 0.6394318547759452 0.9854045533603532 0.3244253939363182 1.0 0.9343862738814418 4 P46108 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.4323386915542472 0.9802307542785216 0.326972226842726 1.0 0.9343862738814418 16 P10321,P01889,Q6P179,Q9NZ08,O95487 5
Rho gtpase effectors 0.2779869041938475 0.9703244020247006 0.331884817658125 1.0 0.9343862738814418 122 Q12834,Q7L7X3,Q7L576,Q96F07,Q9UQB8,Q16537,Q13509,Q9NSK0,Q13362,O75116,P33176,Q96EA4,Q96FJ2,Q86VI3,Q13576,Q07866,P04350,P30153,P28482,Q8WYP5,P30154,Q13153 22
Selective autophagy 0.3640553132720557 0.9691617560223208 0.3324644891486097 1.0 0.9343862738814418 33 P67870,Q8N4H5,Q13509,P04350,P54619,P21796,Q15388,P08670,P54646,P50542,Q9NS69,Q13315,Q96FJ2 13
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.5874384236453143 0.9646378383040632 0.3347262402869375 1.0 0.9343862738814418 5 O15111,Q13546,Q14258,Q7Z434 4
Cell cycle checkpoints 0.291944217625782 0.9637609633858182 0.335165782060455 1.0 0.9343862738814418 148 P20618,P43034,Q12834,Q7L7X3,Q14738,P25787,P24941,O96017,Q16537,Q9Y619,Q9Y266,Q9UJX3,P61289,Q8NI77,P63167,Q06323,Q92530,Q15005,Q13315,Q14191,Q9UQ84,Q13362,Q13042,P49721,P49736,P14635,Q9UJX4,Q96EA4,Q2NKX8,P06493,Q8NFH4,Q96FJ2,O00487,Q99640,Q9UL46,Q96DE5,O00231,P30153,Q96BD8,P42771,Q9UJX2,Q9NWV8,Q8WYP5,Q7Z460,P30154,Q8WXE1,Q14566,Q9H1A4 48
Parasite infection 0.3800052539174064 0.9548445680977748 0.3396563053218715 1.0 0.9343862738814418 23 P46108,Q14185,Q7L576,Q96F07,Q9UQB8 5
Pp2a mediated dephosphorylation of key metabolic factors 0.761846153846142 0.9528165569006914 0.3406830238976637 1.0 0.9343862738814418 3 P30154,P30153 2
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.761846153846142 0.9528165569006914 0.3406830238976637 1.0 0.9343862738814418 3 P30154,P30153 2
Notch hlh transcription pathway 0.6313005229862896 0.9521705401695856 0.3410104990130822 1.0 0.9343862738814418 4 Q04721 1
Formation of tubulin folding intermediates by cct tric 0.4340976055550946 0.9514851855374832 0.341358135348659 1.0 0.9343862738814418 12 P78371,Q13509,P04350,Q99832,Q9BUF5 5
Regulation of pten localization 0.7603814211012045 0.9507451058629496 0.3417337848320896 1.0 0.9343862738814418 2 P46934 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4053230528947936 0.9367880180762808 0.3488676098782517 1.0 0.9464396682048664 18 P78371,Q13509,P04350,O60925,Q99471,Q9UHV9,P61758,Q99832,Q9BUF5 9
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5266180383966463 0.929760651401514 0.3524950236749631 1.0 0.94886741838086 7 P14635,P06493 2
E3 ubiquitin ligases ubiquitinate target proteins 0.4037552959218227 0.9261757069020408 0.3543546751568578 1.0 0.9507269158809192 18 O75150,Q9GZS3,Q6PD62,Q92541,P50542,Q9NS91 6
Costimulation by the cd28 family 0.4109168471528251 0.9060973788476332 0.3648843125771042 1.0 0.9507269158809192 17 Q13362,P42345,P31751,P30153,Q16537,P30154,Q13153 7
Erks are inactivated 0.5738347919413774 0.905565981078345 0.3651656216489085 1.0 0.9507269158809192 5 P30154,P30153,P28482 3
Protein ubiquitination 0.3656697947785492 0.9032554611593412 0.3663903288586778 1.0 0.9507269158809192 26 O75150,Q9GZS3,Q6PD62,Q93009,Q92541,P50542,Q9NS91,A0AVT1,P49427 9
Cytosolic iron sulfur cluster assembly 0.5355761946121089 0.8945736719228912 0.3710150310887474 1.0 0.9507269158809192 6 P18074,Q96T76,Q6FI81,Q9Y5Y2 4
Activation of the pre replicative complex 0.3973767648232712 0.8831048069798879 0.3771796472103395 1.0 0.9507269158809192 18 Q14181,Q9Y619,P56282,Q14566 4
Transcriptional regulation of pluripotent stem cells 0.7425407566902598 0.8811167145545042 0.3782546513500642 1.0 0.9507269158809192 2 Q99626 1
Interleukin 23 signaling 0.7425407566902584 0.8811167145544985 0.3782546513500673 1.0 0.9507269158809192 2 P07237 1
Interleukin 21 signaling 0.7425407566902581 0.881116714554496 0.3782546513500686 1.0 0.9507269158809192 2 P42224 1
Interleukin 9 signaling 0.7425407566902581 0.881116714554496 0.3782546513500686 1.0 0.9507269158809192 2 P42224 1
Diseases of signal transduction by growth factor receptors and second messengers 0.2867974966291999 0.8800250964246957 0.3788457142690091 1.0 0.9507269158809192 148 P20618,Q14738,P25787,P67936,Q16537,Q9UBV2,Q6UWU4,Q13573,Q9H6R7,P26641,P42345,P61289,P30876,Q92542,Q92530,Q7Z569,Q99956,Q13438,O95684,P52298,Q13362,P42224,P31751,P49721,P21359,P33176,Q7Z2W4,Q8IWJ2,Q6WCQ1,Q9NRY5,Q07866,P06753,Q92734,P19174,P51797,O95429,P30153,Q9UL46,Q96PU8,P51114,P28482,P30154,Q92614 43
Inositol phosphate metabolism 0.5155445956064955 0.8774431630504429 0.380245977494074 1.0 0.9507269158809192 7 Q9NPH2,Q9BW91,P29218,P19174 4
Transcriptional regulation by runx2 0.322939871207766 0.8742895550503138 0.3819605860471702 1.0 0.9507269158809192 51 P20618,P25787,O43242,Q13200,P49841,P61289,Q06323,Q92530,P11802,P63208,P62333,P42224,P31751,P49721,P14635,P06493,Q9UNE7,Q99436,O00487,P06400,O00231,Q9UL46,P62195,P28074,P28482,P60900 26
Rac2 gtpase cycle 0.3483227535668853 0.8715621969587088 0.3834472612062307 1.0 0.9507269158809192 39 P49257,Q14185,Q13505,Q07960,Q13153,O15173,Q8TAA9,Q86XL3,Q86Y07 9
Rhobtb gtpase cycle 0.3527232211314777 0.8703415684944191 0.3841137685654243 1.0 0.9507269158809192 30 P38159,O75116,Q8N684,P62995,P08670,Q96DH6,O43396 7
Plasma lipoprotein assembly 0.7351584127960726 0.8526111827791946 0.3938749590769252 1.0 0.9507895641451092 2 P07237 1
Chylomicron assembly 0.7351584127960726 0.8526111827791946 0.3938749590769252 1.0 0.9507895641451092 2 P07237 1
Extracellular matrix organization 0.3528665373050228 0.851400566058135 0.3945468774208791 1.0 0.9507895641451092 29 P13674,O15460,Q32P28,O00469,O75718,P07237 6
The phototransduction cascade 0.6061470683981343 0.8502812700184534 0.3951687273111968 1.0 0.9507895641451092 4 P49356 1
Rhoa gtpase cycle 0.3260381637890357 0.8461671052382542 0.3974595297295815 1.0 0.9507895641451092 49 Q86VI3,O75116,Q07960,Q13190,P30519,Q8TAA9,O15173 7
Irf3 mediated induction of type i ifn 0.5600369458127998 0.8461105593968093 0.3974910706211099 1.0 0.9507895641451092 5 Q9UJV9,P12956,P49959,P13010 4
Class i mhc mediated antigen processing presentation 0.2688242191352427 0.8391310994824425 0.401395746058736 1.0 0.9535312061244102 120 P20618,Q15369,Q9Y4B6,Q12834,Q13617,P01889,P25787,Q8IWV8,Q9ULT8,Q9UJX3,P52888,P61289,P19474,P46934,P10321,Q06323,Q92530,Q6P179,A0AVT1,P49427,O95487,Q13042,Q15345,P49721,Q9UJX4,O95486,Q9Y385,Q13049,Q9UNE7,Q9Y6B6,O00487,Q9UL46,Q9UJX2,Q9NZ08,Q9BSL1,Q9H1A4 36
Signaling by cytosolic fgfr1 fusion mutants 0.4867895430988188 0.8384593224820398 0.4017727842101113 1.0 0.9535312061244102 8 Q92614,P42224,O95684 3
Constitutive signaling by akt1 e17k in cancer 0.6020533182471833 0.833857636434898 0.404361211969972 1.0 0.9552002099086584 4 P42345,P31751 2
Dap12 interactions 0.5214803718020151 0.8304743565106865 0.4062706405195708 1.0 0.9556839973796084 6 P01889,P10321 2
Interleukin 2 family signaling 0.6005147597573463 0.8276984120771296 0.4078413186501093 1.0 0.9556839973796084 4 P42224,P40763 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6005147597573463 0.8276984120771296 0.4078413186501093 1.0 0.9556839973796084 4 P42224,P40763 2
M phase 0.3129069026986298 0.8157225089423883 0.4146588622074201 1.0 0.966983696473378 210 Q9H6D7,P20618,P43034,Q12834,Q7Z5K2,Q7L7X3,O43805,P25787,Q15154,Q16537,Q9Y266,Q9UJX3,Q99986,P63151,Q8NFH5,P61289,Q8NI77,Q13509,P35658,Q92530,O94927,O15078,P42166,O95684,Q15005,Q9BSJ2,Q86XL3,Q86Y07,Q9BUF5,Q01105,Q13362,Q13042,Q14674,P49721,P14635,Q9UQN3,P42167,O75935,Q9UJX4,Q96EA4,Q9H8Y8,Q2NKX8,P06493,Q13561,Q96FJ2,Q29RF7,P67870,P61163,Q9BTX1,P06400,P04350,Q96DE5,Q9UL46,P30153,Q92973,Q96BD8,Q7Z4H7,P42695,Q9UJX2,P28482,Q8WYP5,Q96CS2,P30154,Q9H1A4 64
Sensory perception 0.362381749691568 0.8070738644282156 0.4196239286471908 1.0 0.9716532569184226 22 P49356,P53582 2
Interleukin 3 interleukin 5 and gm csf signaling 0.5158533655337063 0.8050589591695753 0.420785657439936 1.0 0.9716532569184226 6 P46108 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.326644669599981 0.8010747852157074 0.4230883525266766 1.0 0.9716532569184226 47 P20618,P25787,O43242,P08238,Q13200,P61289,Q9BVA1,Q13509,Q06323,Q92530,P62333,Q9BUF5,P49721,P14635,P06493,Q99436,O00487,P04350,O00231,Q9UL46,P62195,P28074,P53350,P60900 24
Fceri mediated ca 2 mobilization 0.7186336661522212 0.7951651608820142 0.4265174347030847 1.0 0.9716647699010034 3 O43865 1
Cytoprotection by hmox1 0.2999460237078916 0.7948151631849798 0.42672102925818 1.0 0.9716647699010034 62 Q92530,P49721,P09601,Q9UL46,P30519,P33527 6
Antigen processing ubiquitination proteasome degradation 0.287540795254685 0.790332223265708 0.4293337728911581 1.0 0.976014092546348 96 P20618,Q15369,Q9Y4B6,Q12834,Q13617,P25787,Q8IWV8,Q9ULT8,Q9UJX3,P52888,P61289,P19474,P46934,Q06323,Q92530,A0AVT1,P49427,Q13042,Q15345,P49721,Q9UJX4,Q9Y385,Q13049,Q9UNE7,O00487,Q9UL46,Q9UJX2,Q9BSL1,Q9H1A4 29
Degradation of beta catenin by the destruction complex 0.3161957382569682 0.7730480730087108 0.4394939306890084 1.0 0.9902053489624548 50 P20618,Q14738,P25787,P56545,O43242,Q16537,Q13200,P49841,P61289,Q06323,Q92530,P63208,P62333,Q13362,P49721,Q04726,Q99436,O00487,O00231,Q9UL46,P30153,P62195,P28074,P60900,P30154 25
Signaling by pdgf 0.4528658323792552 0.7705704300479432 0.4409615938841484 1.0 0.9902053489624548 9 P46109,P19174,P42224,P46108 4
Downstream signal transduction 0.4528658323792552 0.7705704300479432 0.4409615938841484 1.0 0.9902053489624548 9 P46109,P19174,P42224,P46108 4
Condensation of prophase chromosomes 0.4033031003476006 0.7690823950052499 0.4418443986053666 1.0 0.9902053489624548 12 Q01105,P06493,P06400 3
Rac1 gtpase cycle 0.3157627936647431 0.7685804747213119 0.442142400267939 1.0 0.9902053489624548 50 Q86VI3,Q96N67,Q14185,Q07960,Q96F07,Q9UQB8,Q8TAA9,Q13153,Q86Y07 9
Darpp 32 events 0.4920468196137498 0.7676330875675903 0.4427051992121558 1.0 0.9902053489624548 7 P30154,P30153 2
Metabolism of polyamines 0.33596914678678 0.7509830269371218 0.4526628706315454 1.0 1.0 38 Q92530,Q6QHF9,P49721,Q9UL46 4
Rho gtpases activate wasps and waves 0.3949206285578517 0.7445956349794987 0.4565162075192097 1.0 1.0 16 Q7L576,Q96F07,Q9UQB8 3
Signaling by notch 0.2948829515835272 0.7376243859531334 0.4607427324238056 1.0 1.0 61 Q92530,P25787,P49721,Q9UL46,P67809,Q9UBV2 6
Signaling by receptor tyrosine kinases 0.2618163221129988 0.7351724483059907 0.4622344762767119 1.0 1.0 119 Q96N67,Q7L576,Q96F07,Q9UQB8,Q96P70,P42345,P09651,P50570,P46934,P30876,O43865,Q92542,P46108,Q9UI12,Q93050,Q9NZ52,P52597,P52298,P42224,P31751,P31943,O75116,Q16539,P46109,Q96S59,Q9Y487,Q14185,P30153,P28482,P30154,Q13153 31
Hedgehog off state 0.3125133844090984 0.735157127647286 0.4622438057370759 1.0 1.0 50 P20618,P25787,O43242,Q13200,P49841,P61289,Q9BVA1,Q13509,Q06323,Q92530,Q9Y366,P63208,P62333,Q9BUF5,P49721,Q8NCM8,Q99436,O00487,P04350,O00231,Q9UL46,P62195,P28074,P60900 24
Post chaperonin tubulin folding pathway 0.4456966349894682 0.7341180311580366 0.4628768050231628 1.0 1.0 9 P04350,Q15813,Q13509,Q9BUF5 4
Regulation of tp53 activity through acetylation 0.3964084990179003 0.7289233750244163 0.4660485353573258 1.0 1.0 12 O95696 1
Gastrin creb signalling pathway via pkc and mapk 0.5721760541705175 0.7157635315427263 0.4741373742472263 1.0 1.0 4 P28482,P62993,Q15418 3
Carnitine metabolism 0.4928359346286994 0.7024036057020506 0.482427497306005 1.0 1.0 6 P23786 1
Insulin receptor signalling cascade 0.4921396026573289 0.6993360385405115 0.4843420499441282 1.0 1.0 6 P31751 1
Nuclear envelope ne reassembly 0.306204430100614 0.6986349419169801 0.484780201116552 1.0 1.0 51 Q13509,Q9BTX1,P04350,Q9UQN3,P14635,P42167,P30153,Q86XL3,P42166,P06493,P63151,Q8WYP5,Q99986,Q8NFH5,Q86Y07,Q9BUF5 16
Assembly of the hiv virion 0.6939403260535353 0.6976168917935744 0.4854168148962348 1.0 1.0 2 Q9H9H4 1
Regulation of innate immune responses to cytosolic dna 0.5665402959207271 0.6938987769359846 0.487745690666872 1.0 1.0 4 Q13049 1
G beta gamma signalling through pi3kgamma 0.6920947400799886 0.6908706036988238 0.4896468611009266 1.0 1.0 2 P31751 1
Growth hormone receptor signaling 0.5656326767962876 0.6903915584561456 0.4899479838670841 1.0 1.0 4 P42224,P28482 2
Signaling by egfr in cancer 0.5635580178516504 0.6823897540132424 0.4949925328023212 1.0 1.0 4 P07900,P62993,P19174 3
Constitutive signaling by ligand responsive egfr cancer variants 0.5635580178516504 0.6823897540132424 0.4949925328023212 1.0 1.0 4 P07900,P62993,P19174 3
Constitutive signaling by egfrviii 0.5635580178516504 0.6823897540132424 0.4949925328023212 1.0 1.0 4 P07900,P62993,P19174 3
Cd163 mediating an anti inflammatory response 0.6890187634574036 0.6796690229270171 0.4967140544762989 1.0 1.0 2 Q16539 1
G alpha 12 13 signalling events 0.4342705246503185 0.676616000887904 0.4986496242443718 1.0 1.0 9 O75116,Q14344,Q9UBI6,Q92974 4
Synthesis of dna 0.2876404190301866 0.6750479236847003 0.4996453178720268 1.0 1.0 81 Q9Y2S7,P61289,Q13042,P49721,Q92530,P25787,Q9BRT9,P24941,Q9UL46,Q9UJX4,Q14181,Q9Y619,P56282,Q9UJX2,Q9UJX3,P49643,Q14566,Q9H1A4 18
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.6865579821593382 0.6707465772143184 0.5023819854752227 1.0 1.0 2 P12814 1
Signaling by erythropoietin 0.6831770441749182 0.6704883745964314 0.5025465148893791 1.0 1.0 3 P46109 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3557204197616366 0.6685531925333165 0.503780539578865 1.0 1.0 19 P07237,Q02818,Q07065,O43852 4
Mapk family signaling cascades 0.2839956962290261 0.6624099467796978 0.5077085307324682 1.0 1.0 87 P61289,Q13362,P49356,P49721,Q92530,P25787,Q7Z569,P21359,Q9UL46,P30153,Q9Y4G8,Q16537,P06493,Q96P70,Q13153,P28482,P30154,P07196 18
Netrin 1 signaling 0.3861635469640696 0.658792815841079 0.5100288212497732 1.0 1.0 13 Q14185,Q00169 2
Regulation of pyruvate dehydrogenase pdh complex 0.4293605411605892 0.6521625521625459 0.5142963148646709 1.0 1.0 9 Q15118 1
Met activates rap1 and rac1 0.4799573544847929 0.6460967258375135 0.5182167156671829 1.0 1.0 6 Q96N67,P46108 2
Diseases of dna repair 0.3829706595553765 0.6404415237609595 0.5218855945204193 1.0 1.0 13 Q13315,Q14191,Q9UQ84 3
Pre notch processing in the endoplasmic reticulum 0.6735384615384595 0.6375569811186571 0.5237621066017115 1.0 1.0 3 Q04721,Q8NBL1 2
Signaling by insulin receptor 0.3767306967391408 0.6333508154867177 0.526504576222343 1.0 1.0 16 Q9UI12,P31751,Q93050 3
G alpha i signalling events 0.3368467583637516 0.6327320713314666 0.5269086226418129 1.0 1.0 23 P52292,O43865,Q13555,Q14738,Q9NZJ7,Q9NRV9,P07602,P05067,P30153,P28482,P30154 11
Regulation of ras by gaps 0.3221114415539516 0.6295043808164225 0.5290189016058666 1.0 1.0 38 Q92530,P49721,P21359,Q9UL46 4
Cd28 dependent pi3k akt signaling 0.6695384615384503 0.6240291790083877 0.5326084224561296 1.0 1.0 3 P42345,P31751 2
Pyrimidine salvage 0.6694066071981052 0.6235846924582078 0.5329003661317571 1.0 1.0 3 Q08623 1
Cdc42 gtpase cycle 0.3227431161356758 0.620811524095218 0.5347236399526976 1.0 1.0 35 Q86VI3,Q96N67,Q07960,Q9UQB8,Q13153,Q8TAA9 6
Tp53 regulates transcription of caspase activators and caspases 0.6671244549013626 0.6159062601243377 0.5379563896568378 1.0 1.0 3 P42575 1
Cargo concentration in the er 0.3725517011360937 0.6082477479208778 0.5430231707606223 1.0 1.0 16 P49257,O95487,Q13190,Q96PC5 4
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4188689963293723 0.6005047516709272 0.5481698950973075 1.0 1.0 9 P14635,P06493 2
Rac3 gtpase cycle 0.3198095850481832 0.5993956537949959 0.5489090745558334 1.0 1.0 36 P49257,Q07960,Q9UQB8,O15173,Q8TAA9,Q13153,Q86Y07 7
Regulation of hmox1 expression and activity 0.3091615550831318 0.5934578167473589 0.5528748055875059 1.0 1.0 45 Q92530,P09601,P49721,Q9UL46 4
Post translational modification synthesis of gpi anchored proteins 0.4530702015089336 0.5910986710128562 0.5544543102834623 1.0 1.0 7 Q9ULX3,O43292 2
Uptake and function of diphtheria toxin 0.5379811308246283 0.5856548884842427 0.5581074549880827 1.0 1.0 4 P08238,Q16881 2
Hedgehog on state 0.312521336346238 0.582041188363864 0.5605389376841061 1.0 1.0 42 Q92530,Q6PHR2,P49721,Q9UL46 4
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3175013763362396 0.580578634658164 0.5615244752869903 1.0 1.0 30 O60884,P63167,Q13509,P61163,P31689,P04350,O75935,P54652,Q13561,Q9UJW0,Q96FJ2,Q9BUF5 12
Ros and rns production in phagocytes 0.4144641144405161 0.579082189999556 0.562533716726785 1.0 1.0 9 Q93050 1
Methylation 0.4612145591054007 0.5660038283189182 0.5713911780615788 1.0 1.0 6 Q99707,P21964 2
Deubiquitination 0.2732870923839824 0.5610146562131303 0.5747875459476488 1.0 1.0 92 P45880,Q12834,P49721,Q92530,P25787,Q9UL46,P06493,Q9NWV8 8
Platelet activation signaling and aggregation 0.2774819654024492 0.5573103397805157 0.5773154124010071 1.0 1.0 56 Q8NCG7,O43852,Q8NBX0 3
Orc1 removal from chromatin 0.2993237086246522 0.5563368717057863 0.5779805855532734 1.0 1.0 48 P20618,P25787,P24941,Q9Y619,O43242,Q13200,P33992,P61289,Q06323,Q92530,P63208,P62333,P49736,P49721,P33991,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900,Q14566 23
Cdt1 association with the cdc6 orc origin complex 0.3132833049228369 0.5539193226850414 0.5796340605010935 1.0 1.0 38 Q92530,P25787,P49721,Q9UL46 4
Signaling by alk in cancer 0.3142432473785382 0.5484675559765618 0.5833709007617651 1.0 1.0 33 Q9NR09,Q07866,P06753,P40763,Q92734,P19174,P33176,P67936,Q8IWJ2,P28482,P63208,Q9H6R7,P26641 13
Vxpx cargo targeting to cilium 0.4078355063786765 0.5471729956000778 0.5842598867819642 1.0 1.0 9 O60645,Q92538,Q96KP1,O00471,Q9UPT5 5
Displacement of dna glycosylase by apex1 0.5274406434357767 0.5469626079177139 0.584404421391532 1.0 1.0 4 P13051 1
Fcgr3a mediated il10 synthesis 0.4869294923109006 0.5443555116664334 0.5861968538241702 1.0 1.0 5 O43865 1
Signaling by hippo 0.4553219077535668 0.5413522038104228 0.5882648446631664 1.0 1.0 6 P31946,Q07157,Q13188,Q4VCS5 4
Synthesis of ip3 and ip4 in the cytosol 0.6484158720393813 0.5374289207892331 0.5909713707125437 1.0 1.0 2 P19174 1
Rnd1 gtpase cycle 0.3519398847126462 0.5330077134937421 0.5940282408000241 1.0 1.0 17 Q9BXS4,Q8TAA9,O43396,P51648 4
Tp53 regulates transcription of cell death genes 0.4514211790733151 0.5251890200486252 0.5994517970467172 1.0 1.0 6 P42575,Q92696 2
Interleukin 27 signaling 0.638912238249576 0.5234916876967235 0.6006321340229364 1.0 1.0 3 P42224 1
Interleukin 35 signalling 0.638912238249576 0.5234916876967235 0.6006321340229364 1.0 1.0 3 P42224 1
Senescence associated secretory phenotype sasp 0.3236826921390907 0.5162132999066095 0.6057054422201962 1.0 1.0 20 Q13042,Q9UJX3,Q9UJX4,P24941,Q96DE5,P42771,P28482,P11802,Q9UJX2,Q9H1A4 10
Mismatch repair 0.3583607389853067 0.514796043794864 0.6066955502103533 1.0 1.0 12 Q9UQ84 1
Synthesis of pips at the late endosome membrane 0.6356923076923054 0.5132651515467582 0.6077658572732341 1.0 1.0 3 O00443,Q13614 2
Glucagon like peptide 1 glp1 regulates insulin secretion 0.5167743921206568 0.5086161371201816 0.6110213155479174 1.0 1.0 4 Q9UBI6,P10644,P46940 3
Mhc class ii antigen presentation 0.2723127823570958 0.5018886770091298 0.6157458305939545 1.0 1.0 56 O43747,P50570,Q8NI77,Q13509,Q9NSK0,O95487,Q9NS87,Q9BXS5,Q9BUF5,O75935,P61966,O95486,P33176,Q13561,Q9UJW0,Q96FJ2,Q07866,P04350,P52732 19
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4448300766630462 0.4981766090936551 0.6183595676138387 1.0 1.0 6 Q99570,O00459,P31751,O14654 4
Rhog gtpase cycle 0.305822633559984 0.4972117855625818 0.6190397112982207 1.0 1.0 39 P49257,Q14185,Q07960,Q7L576,Q13190,O15173,Q8TAA9,Q86XL3,Q86Y07 9
Mitotic prophase 0.2729898985412678 0.4925515884586322 0.6223294619304722 1.0 1.0 61 Q01105,Q9BTX1,P35658,P06400,P30154,P30153,Q9H8Y8,P42695,P06493,P28482,Q99986,Q86Y07 12
Traf3 dependent irf activation pathway 0.6339587819132644 0.4897097297720368 0.6243393158349091 1.0 1.0 2 Q14258 1
Traf6 mediated irf7 activation 0.6339587819132644 0.4897097297720368 0.6243393158349091 1.0 1.0 2 Q14258 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.3954502586284167 0.4887266020306859 0.6250352676815021 1.0 1.0 9 Q13315,Q9UQ84 2
Resolution of d loop structures 0.3954502586284167 0.4887266020306859 0.6250352676815021 1.0 1.0 9 Q13315,Q9UQ84 2
Insulin receptor recycling 0.3836370721713988 0.4855522752487498 0.6272846406202324 1.0 1.0 10 Q93050 1
Translation of sars cov 2 structural proteins 0.3578707700510265 0.4802141597280953 0.6310751193610886 1.0 1.0 15 P04844,Q13724,Q16706,P26572,Q14697 5
Signaling by fgfr 0.3121304564370927 0.4783961356856278 0.632368283517244 1.0 1.0 25 P30876,P31943,P30153,P28482,P52597,P52298,P09651 7
Signaling by fgfr2 0.3121304564370927 0.4783961356856278 0.632368283517244 1.0 1.0 25 P30876,P31943,P30153,P28482,P52597,P52298,P09651 7
Respiratory electron transport 0.2783669555810054 0.4718428976086792 0.6370389289701668 1.0 1.0 53 Q9Y6M9,Q9NPL8,Q8TB37,O95182,Q9UDW1,O43676,Q8N183 7
Protein localization 0.2699400907625061 0.4678961907819842 0.6398588276742345 1.0 1.0 83 Q8N4H5,Q6QHF9,P09601,Q13505,Q9Y584,P51648,O75874,Q13190,P50542,Q9NS69,Q99595 11
Regulation of mrna stability by proteins that bind au rich elements 0.2700984107490438 0.4675921749428007 0.6400762618439351 1.0 1.0 59 Q01105,Q92945,Q92530,P49721,Q9UL46 5
Myd88 independent tlr4 cascade 0.3156637527321467 0.4637207894648283 0.642847800468693 1.0 1.0 20 Q14738,Q13546,P05067,P30153,Q16539,P28482,P63208,P30154 8
Rhoh gtpase cycle 0.3099290051466832 0.4627780003669069 0.6435235018432359 1.0 1.0 25 Q9Y6M7,O75116,Q99707,Q9BXS4,Q8TAA9 5
Tyrosine catabolism 0.6241156567210144 0.4582401765876245 0.6467798983382884 1.0 1.0 2 O43708 1
Factors involved in megakaryocyte development and platelet production 0.2865421861008705 0.4562001147412253 0.6482460829195862 1.0 1.0 49 Q07866,Q8NI77,Q13509,Q96N67,P04350,Q9NSK0,P24941,P33176,Q14185,O60333,P52732,Q9NS87,Q9H4M9 13
Maturation of sars cov 1 spike protein 0.4638014044320532 0.4561805999599818 0.648260114717268 1.0 1.0 5 Q13724,Q14697 2
Regulation of pten stability and activity 0.2985327672751993 0.4509020581331567 0.6520601401025363 1.0 1.0 41 P20618,P25787,O43242,Q13200,P61289,P46934,Q06323,Q92530,P62333,P31751,P49721,Q9UNE7,P67870,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900 20
G2 m checkpoints 0.268485081382922 0.4507396059107801 0.6521772336161931 1.0 1.0 83 P49721,Q92530,P25787,Q99640,Q9UL46,P06493,Q9NWV8,Q8WXE1,Q14566,Q9UQ84 10
Assembly and cell surface presentation of nmda receptors 0.4030991432829178 0.4476134193048091 0.6544322167142103 1.0 1.0 8 P07196,Q13509 2
Cyclin a cdk2 associated events at s phase entry 0.2957445404489212 0.4465644459293009 0.6551895713212659 1.0 1.0 43 P20618,P25787,P24941,O43242,Q13200,P61289,Q06323,Q92530,P11802,P63208,P62333,P31751,P49721,Q99436,O00487,P06400,O00231,Q9UL46,P62195,P28074,P60900 21
Signaling by the b cell receptor bcr 0.290806296303515 0.4282472102273356 0.668471148109897 1.0 1.0 45 O43865,Q92530,P25787,P49721,Q9UL46 5
Tcf dependent signaling in response to wnt 0.2675685296873448 0.4275797232397665 0.6689571310693785 1.0 1.0 64 Q13362,P67870,P31751,Q92530,P25787,P49721,P30153,Q9UL46,Q9HCK8,Q16537,P30154,Q70CQ2 12
Signaling by fgfr4 0.4268127734658924 0.4264545398825229 0.6697766668628797 1.0 1.0 6 P30153,P28482 2
Signaling by fgfr3 0.4268127734658924 0.4264545398825229 0.6697766668628797 1.0 1.0 6 P30153,P28482 2
Signaling by fgfr1 0.4268127734658924 0.4264545398825229 0.6697766668628797 1.0 1.0 6 P30153,P28482 2
Signaling by fgfr in disease 0.3060335703373704 0.417734109698842 0.6761415304718077 1.0 1.0 23 P42224,P30876,P19174,O95429,O95684,Q92614,P52298 7
Notch3 intracellular domain regulates transcription 0.6013562430977407 0.4089746166926657 0.6825582891348347 1.0 1.0 3 P42224 1
Negative regulation of the pi3k akt network 0.3377295262775236 0.4082983075944051 0.6830546816474607 1.0 1.0 16 Q13362,P31751,Q14738,P30153,Q16537,P28482,P30154 7
Synthesis of ip2 ip and ins in the cytosol 0.4866621764326316 0.4054490138033248 0.6851474891101692 1.0 1.0 4 P29218 1
Regulation by c flip 0.6062749923100685 0.4034997065033288 0.6865806506051426 1.0 1.0 2 Q13546 1
Caspase activation via extrinsic apoptotic signalling pathway 0.6062749923100685 0.4034997065033288 0.6865806506051426 1.0 1.0 2 Q13546 1
Caspase activation via death receptors in the presence of ligand 0.6062749923100685 0.4034997065033288 0.6865806506051426 1.0 1.0 2 Q13546 1
Diseases of glycosylation 0.3052982047868009 0.3979395132332214 0.6906747727899811 1.0 1.0 20 Q04721,Q2TAA5,Q13724,Q8NCH0,Q9BT22 5
Polymerase switching 0.3423266079165448 0.3965376790842665 0.6917084171931369 1.0 1.0 15 Q9Y2S7,Q14181,P49643 3
Akt phosphorylates targets in the cytosol 0.5966153846153863 0.3953223363477225 0.6926050170872651 1.0 1.0 3 P49841,P31751 2
Deactivation of the beta catenin transactivating complex 0.3639368601242497 0.3930959703317002 0.694248600246409 1.0 1.0 10 P31751 1
Negative regulation of fgfr2 signaling 0.4408266178667923 0.3736882669178702 0.7086362556071022 1.0 1.0 5 P30153 1
Negative regulation of fgfr4 signaling 0.4408266178667923 0.3736882669178702 0.7086362556071022 1.0 1.0 5 P30153 1
Negative regulation of fgfr1 signaling 0.4408266178667923 0.3736882669178702 0.7086362556071022 1.0 1.0 5 P30153 1
Negative regulation of fgfr3 signaling 0.4408266178667923 0.3736882669178702 0.7086362556071022 1.0 1.0 5 P30153 1
Spry regulation of fgf signaling 0.4408266178667923 0.3736882669178702 0.7086362556071022 1.0 1.0 5 P30153 1
Opioid signalling 0.3241926853509155 0.3728837826752228 0.7092349425183371 1.0 1.0 17 P52292,O43865,Q13555,Q14738,P30153,P28482,P30154 7
Diseases of immune system 0.5870769230769235 0.3684572223855417 0.7125323365084153 1.0 1.0 3 P09429,O15111 2
Adaptive immune system 0.2772149756014203 0.3646496933987644 0.7153729152809296 1.0 1.0 196 P20618,Q15369,Q9Y4B6,Q12834,Q13617,P01889,Q14738,P25787,O43747,Q8IWV8,Q16537,Q9ULT8,Q9UJX3,P42345,P52888,P61289,P50570,P46934,Q8NI77,O43865,P19474,Q13509,Q92530,P63167,P10321,Q9NSK0,Q6P179,A0AVT1,P49427,Q9NS87,O95487,Q9BXS5,Q9BUF5,Q13362,Q13042,P31751,P49721,Q9UJX4,O75935,P61966,O95486,P33176,Q9Y385,Q13049,Q9UDY8,Q13561,Q9UJW0,Q96FJ2,Q07866,P61163,P19174,P04350,P30153,Q9UL46,P52732,Q9UJX2,Q9NZ08,Q9BSL1,P30154,Q13153,Q9H1A4 61
Oncogenic mapk signaling 0.2920824689723411 0.3644984835247289 0.7154858060018867 1.0 1.0 28 Q9NRY5,Q7Z569,P21359,Q96PU8,Q99956,Q7Z2W4,P51114,Q6WCQ1,P28482,Q6UWU4 10
Nr1h2 and nr1h3 mediated signaling 0.437393524152473 0.361862552473369 0.717454744987085 1.0 1.0 5 O00767 1
Thromboxane signalling through tp receptor 0.5843076923076937 0.3608131380169636 0.7182391407677848 1.0 1.0 3 Q14344,Q9UBI6 2
Polymerase switching on the c strand of the telomere 0.3146471206198594 0.3602153979092309 0.7186860606851275 1.0 1.0 18 Q9Y2S7,Q14181,P49643 3
Dag and ip3 signaling 0.3821613699344401 0.3600436102400604 0.7188145211575079 1.0 1.0 8 P52292,O43865,P19174 3
G1 s dna damage checkpoints 0.2873735544368234 0.3593918852610254 0.7193019444184365 1.0 1.0 41 P20618,P25787,P24941,O43242,Q13200,P61289,Q06323,Q92530,P62333,Q13315,P49721,Q99436,O00487,O00231,Q9UL46,P62195,P42771,P28074,P60900,O96017 20
Recycling of eif2 gdp 0.3965674733824638 0.3568273675306978 0.7212210468588522 1.0 1.0 7 P49770 1
Cell cycle mitotic 0.3064316711439921 0.3567706500666485 0.7212635100687737 1.0 1.0 268 Q12834,Q7L7X3,Q15154,Q16537,Q9Y266,Q9UJX3,Q99986,Q8NFH5,P61289,O95684,Q15005,P11802,P31350,Q86XL3,Q01105,P49721,O75935,Q9H8Y8,Q2NKX8,P06493,Q29RF7,P42771,Q8WYP5,Q9H1A4,Q9H6D7,Q7Z5K2,P24941,P49005,P63151,Q8NI77,Q92530,P42166,Q9BUF5,Q9Y2S7,Q14674,P14635,P42167,P61163,Q9Y570,Q99640,Q9UL46,Q96DE5,Q92973,Q96BD8,Q9UJX2,P30154,Q14566,P20618,P43034,O43805,P25787,Q9Y619,Q13509,O94927,O15078,Q9BSJ2,Q86Y07,Q13362,Q9BRT9,Q14181,Q13561,Q9BTX1,P04350,P30153,Q7Z4H7,Q96CS2,P56282,P49643,P35658,Q13042,P31751,P00374,Q9UQN3,Q9UJX4,Q96EA4,Q96FJ2,P67870,P06400,P42695,P28482 80
Rho gtpase cycle 0.2618116146225943 0.3514044358233418 0.7252849550302118 1.0 1.0 166 P49257,Q96N67,Q7L576,Q96F07,Q9UQB8,P38159,Q07960,Q9BXS4,Q13190,P30519,Q86XL3,Q86Y07,Q9Y6M7,O75116,Q13505,P08670,O43396,O15173,Q86VI3,Q07065,Q14185,P51648,Q99707,P62995,Q13153,Q8TAA9 26
Transport of small molecules 0.2572237405021921 0.3512818732326037 0.7253768925749511 1.0 1.0 157 P45880,Q70HW3,Q8WTV0,P25787,Q9HD20,P08195,Q9UBV2,Q92530,P09601,Q13438,Q15043,Q9UI12,Q93050,P30519,P49721,Q9NUT2,Q9UL46,Q8TAD4,P33527 19
Signalling to erks 0.3644609211238888 0.3507454326274163 0.7257793378771908 1.0 1.0 9 P46109,P28482,P46108 3
Interferon gamma signaling 0.3291246576488881 0.3505658508853858 0.7259140795550814 1.0 1.0 13 P19474,P10321,P42224,Q12899,O15344,P01889 6
Ub specific processing proteases 0.2609506880949427 0.3493876672884186 0.7267982907457085 1.0 1.0 75 P45880,Q12834,Q92530,P25787,P49721,Q9UL46 6
Ikba variant leads to eda id 0.5868963395878303 0.3477030855988409 0.7280631791259178 1.0 1.0 2 O15111 1
Disorders of transmembrane transporters 0.2606320603383691 0.3459828417622134 0.7293556096391312 1.0 1.0 75 Q9BTX1,P35658,Q92530,P25787,P49721,O75477,Q9UL46,Q13438,P08195,Q9UBV2,Q8NFH5 11
Autophagy 0.2677771811550422 0.345890677112305 0.7294248752935901 1.0 1.0 52 P67870,Q8N4H5,Q13509,Q96FJ2,P04350,Q9UQN3,P54619,P21796,Q15388,P08670,P54646,P50542,Q9NS69,P42345,Q9H9H4,Q13315 16
Abacavir transport and metabolism 0.5859735466010576 0.3451474866624632 0.7299834951761766 1.0 1.0 2 P08183 1
Inactivation of csf3 g csf signaling 0.4321413049655062 0.3440438876777343 0.7308132808401007 1.0 1.0 5 Q15369,P42224,P40763 3
Role of lat2 ntal lab on calcium mobilization 0.5850507536142846 0.3426014070460625 0.7318983433988604 1.0 1.0 2 O00459 1
Interleukin 15 signaling 0.5850507536142846 0.3426014070460625 0.7318983433988604 1.0 1.0 2 P40763 1
Interleukin receptor shc signaling 0.5850507536142846 0.3426014070460625 0.7318983433988604 1.0 1.0 2 O00459 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.4314364004774511 0.341678161510528 0.7325931086484461 1.0 1.0 5 O43747,Q9BXS5 2
Rhod gtpase cycle 0.2851591884356332 0.3344580335088465 0.7380339536814149 1.0 1.0 30 Q9Y6M7,Q07960,O15173,Q8TAA9,Q86Y07 5
Class a 1 rhodopsin like receptors 0.3906145612130058 0.3342874736142889 0.7381626419040093 1.0 1.0 7 Q9NRV9,P07602 2
Peptide ligand binding receptors 0.3906145612130058 0.3342874736142889 0.7381626419040093 1.0 1.0 7 Q9NRV9,P07602 2
Hdr through homologous recombination hrr 0.2909015839784611 0.3329134818224297 0.7391995923663701 1.0 1.0 25 Q9Y2S7,P56282,Q8WXE1,Q13315,Q14191,Q9UQ84 6
Pre notch expression and processing 0.3221369736487293 0.3292986850216823 0.7419299379466229 1.0 1.0 12 Q04721,Q13573,Q9HCE1,Q9UBV2 4
Translation of sars cov 1 structural proteins 0.3877240111318774 0.3235218468406101 0.7463000649868339 1.0 1.0 7 Q13724,Q14697 2
Creb phosphorylation 0.5718240541372007 0.3071760373571567 0.7587093838043506 1.0 1.0 2 Q15418 1
Mapk6 mapk4 signaling 0.2731802480247911 0.3053078082659337 0.7601317295326795 1.0 1.0 47 Q92530,P25787,P49721,Q9UL46,P06493 5
Toll like receptor tlr1 tlr2 cascade 0.3041009186018043 0.3022072008086069 0.7624941152822158 1.0 1.0 18 Q14738,P30153,P05067,Q16539,P28482,P63208,P30154 7
Fgfr2 alternative splicing 0.2961509351439511 0.2980563805523253 0.7656601325484078 1.0 1.0 19 P52298,P52597,P30876,P31943 4
Rnd3 gtpase cycle 0.3033098203403184 0.2979750390227009 0.7657222147085319 1.0 1.0 18 O43396,Q8TAA9,Q07065 3
Metabolism of nitric oxide nos3 activation and regulation 0.4162561576354571 0.2922833405529506 0.7700699952746639 1.0 1.0 5 P50570,O75608,P07900,P35270 4
Rhoc gtpase cycle 0.2808887914465408 0.2919450106305633 0.7703286683012021 1.0 1.0 34 Q86VI3,O75116,Q07960,Q13190,Q8TAA9 5
Sensing of dna double strand breaks 0.4152399247068257 0.2890865109945317 0.7725151757889126 1.0 1.0 5 Q13315 1
Interleukin 20 family signaling 0.555965875936971 0.2868753513890663 0.7742077643303664 1.0 1.0 3 P42224 1
Interleukin 6 family signaling 0.555965875936971 0.2868753513890663 0.7742077643303664 1.0 1.0 3 P42224 1
Interleukin 6 signaling 0.555965875936971 0.2868753513890663 0.7742077643303664 1.0 1.0 3 P42224 1
Gpcr ligand binding 0.3485039541602934 0.2854000044508278 0.775337704126134 1.0 1.0 9 Q9NZJ7,Q9NRV9,P07602,P05067 4
Irs mediated signalling 0.4138745769029592 0.28481395993949 0.7757866765114287 1.0 1.0 5 Q99570,O00459,P31751 3
Runx2 regulates bone development 0.4467321016444701 0.2828754639586987 0.7772723036489178 1.0 1.0 4 P06400 1
Ephrin signaling 0.3757913103338187 0.2803897607000172 0.7791784918984435 1.0 1.0 7 O00560 1
Cross presentation of soluble exogenous antigens endosomes 0.2786501412921666 0.275299367122354 0.783086250654434 1.0 1.0 36 Q92530,P49721,Q9UL46 3
Degradation of axin 0.2786501412921666 0.275299367122354 0.783086250654434 1.0 1.0 36 Q92530,P49721,Q9UL46 3
Ikk complex recruitment mediated by rip1 0.4107142857142758 0.2750246422102993 0.7832973063074895 1.0 1.0 5 O14920,O15111,Q13546,Q6SZW1 4
Fc epsilon receptor fceri signaling 0.2549915726413871 0.2747462860024145 0.7835111679449527 1.0 1.0 54 P61289,O43865,Q92530,P25787,P49721,Q9UL46,Q9UDY8,P28482,Q13153 9
Cellular response to hypoxia 0.2772476570204748 0.2712703883067672 0.7861830795701505 1.0 1.0 39 P20618,Q15369,Q13617,P25787,O43242,Q13200,P61289,Q06323,Q92530,P62333,Q15370,P49721,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900 19
Stabilization of p53 0.2764598874509208 0.2695179140244851 0.7875311586767617 1.0 1.0 40 P20618,P25787,O43242,Q13200,P61289,Q06323,Q92530,P62333,Q13315,P49721,Q99436,O00487,O00231,Q9UL46,P62195,P42771,P28074,P60900,O96017 19
Acyl chain remodelling of pg 0.5542909873885083 0.2634220086972264 0.7922253289750609 1.0 1.0 2 Q8NF37 1
Diseases of mismatch repair mmr 0.546153846153846 0.2632116960176197 0.7923874164465716 1.0 1.0 3 P43246,P52701 2
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2509429462078728 0.2625480536957662 0.7928989427705795 1.0 1.0 63 Q9Y6M9,Q9NPL8,P00846,Q8TB37,O95182,Q9UDW1,O43676,Q8N183 8
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.380778753309835 0.2608425003088993 0.7942139681305611 1.0 1.0 6 P07196 1
Toll like receptor cascades 0.2794163582412645 0.2598291372560636 0.7949955743608967 1.0 1.0 25 P50570,Q14738,Q13546,P05067,P30153,Q16539,P28482,P63208,P30154 9
Cellular response to chemical stress 0.2521526343302913 0.2596119311271551 0.7951631321117498 1.0 1.0 71 Q92530,P49721,P09601,Q9UL46,P30519,P33527 6
Glutathione conjugation 0.3090986662236863 0.2561993352337856 0.7977969219111136 1.0 1.0 13 O15217 1
Trna processing 0.2474275422592357 0.2545515760038017 0.799069464009925 1.0 1.0 56 Q9UJA5,Q5VV42,Q9BVC5,P35658,Q9BTX1,P07814,Q2VPK5,Q9UET6,Q6YHU6,O15091,Q969Y2,Q8NFH5 12
Degradation of dvl 0.2753469922696778 0.2527167728485249 0.8004870856588902 1.0 1.0 37 Q92530,P49721,Q9UL46 3
Regulation of runx2 expression and activity 0.2723003264503036 0.2496089464320051 0.802889779302939 1.0 1.0 42 P20618,P25787,O43242,Q13200,P49841,P61289,Q06323,Q92530,P63208,P62333,P42224,P49721,Q9UNE7,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900 20
Polo like kinase mediated events 0.4329938554568219 0.2451667547942828 0.8063273167887837 1.0 1.0 4 P14635,Q99640 2
Signaling by notch4 0.2706324008887601 0.2440558130635272 0.8071875939343292 1.0 1.0 43 P20618,P25787,O43242,Q13573,Q13200,Q04721,P61289,Q92542,Q06323,Q92530,P63208,P62333,P49721,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900 20
Intrinsic pathway for apoptosis 0.2926447036476307 0.2426848246369478 0.8082495642558396 1.0 1.0 18 P63167,P31751,P40763,P42771,P28482,Q96FJ2 6
Dna replication pre initiation 0.2468900357910529 0.2414914891604616 0.8091742119930152 1.0 1.0 58 Q92530,P25787,P49721,Q9UL46,Q14181,Q9Y619,P56282,Q14566 8
Mitochondrial calcium ion transport 0.3041925208897181 0.2379121940549326 0.8119491975456123 1.0 1.0 16 P45880,Q8IYU8,Q10713,P21796,Q9Y4W6 5
Glycerophospholipid biosynthesis 0.2718493750473327 0.2379117544249426 0.8119495385314808 1.0 1.0 31 P67870,Q9UG56,Q9HCL2,Q9NPH0,P48651,Q8IV08,P35790 7
Dna replication 0.2473251691845926 0.2249313538923228 0.8220326773361106 1.0 1.0 86 Q9Y2S7,P61289,Q13042,P49721,Q92530,P25787,Q9BRT9,P24941,Q9UL46,Q9UJX4,Q14181,Q9Y619,P56282,Q9UJX2,Q9UJX3,P49643,Q14566,Q9H1A4 18
Dna strand elongation 0.271194671227335 0.2246585193841487 0.82224493643157 1.0 1.0 28 Q9Y2S7,Q14181,Q9BRT9,Q14566 4
Lysosome vesicle biogenesis 0.303772021000915 0.2211560258129461 0.8249709477880685 1.0 1.0 14 P50570,P11142,O43747,P05067,P61966,Q10567,P20645,Q9BXS5 8
Hs gag degradation 0.534604737004015 0.2188835552124668 0.8267407569070624 1.0 1.0 2 P54802 1
Asymmetric localization of pcp proteins 0.2703771558808917 0.2180635826167641 0.8273795714552623 1.0 1.0 37 Q92530,P49721,Q9UL46 3
Scf skp2 mediated degradation of p27 p21 0.2674018519398909 0.2085765445483339 0.8347788225833681 1.0 1.0 41 P20618,P25787,P24941,O43242,Q13200,P61289,Q06323,Q92530,P11802,P63208,P62333,P49721,Q99436,O00487,O00231,Q9UL46,P62195,P28074,P60900 19
Purine salvage 0.363412380659068 0.2064984884516515 0.836401545340375 1.0 1.0 6 P27707,P00813,P55263,P00492,P00491 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.2676092523578074 0.2058637664093948 0.8368973294043098 1.0 1.0 40 Q92530,P49721,Q9UL46 3
Activation of atr in response to replication stress 0.2850507398499513 0.2054564514511565 0.8372155189751469 1.0 1.0 18 Q8WXE1,Q14566 2
Rhobtb2 gtpase cycle 0.2716849297446227 0.2054430840429546 0.8372259618860358 1.0 1.0 20 P62995,P38159,O43396,Q96DH6 4
Repression of wnt target genes 0.4148968913511903 0.199410601022924 0.8419415685927691 1.0 1.0 4 Q13547,P56545,Q04726 3
Raf activation 0.2978115513289796 0.1958201617124592 0.8447509288117254 1.0 1.0 14 Q13362,Q7Z569,P30153,Q16537,Q6UWU4,P30154 6
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3071658282656951 0.1955189597996492 0.8449866963239423 1.0 1.0 11 P78371,Q99832,P67870 3
Interleukin 17 signaling 0.2995348879281566 0.1925054180201521 0.8473463243167298 1.0 1.0 15 P30154,P30153,P28482,Q16539 4
Depolymerisation of the nuclear lamina 0.3142024632382693 0.1893290035163817 0.8498349648672217 1.0 1.0 10 P14635,P42166,P06493 3
Ticam1 rip1 mediated ikk complex recruitment 0.4105878731917564 0.189202223946112 0.8499343246887245 1.0 1.0 4 O14920,O15111,Q13546 3
Signaling by braf and raf1 fusions 0.2683784534963764 0.1876222529772582 0.851172780678187 1.0 1.0 21 Q9NRY5,Q96PU8,Q7Z2W4,P51114,Q6WCQ1,P28482 6
Phase ii conjugation of compounds 0.2660244298653629 0.1850457893063646 0.8531931210238257 1.0 1.0 26 Q99707,O15217 2
Regulation of tp53 activity through phosphorylation 0.265097108197134 0.1845678409959749 0.8535680116980573 1.0 1.0 34 P67870,Q92804,P24941,P54619,Q16539,P54646,Q8WXE1,Q13315,Q14191,Q9UQ84 10
Runx2 regulates osteoblast differentiation 0.5094674642590973 0.1843204001748546 0.8537621110739764 1.0 1.0 3 P06400 1
Pka mediated phosphorylation of creb 0.5164564749308082 0.182299586005621 0.8553476235605106 1.0 1.0 2 P10644 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.5164564749308082 0.182299586005621 0.8553476235605106 1.0 1.0 2 P10644 1
Pka activation in glucagon signalling 0.5164564749308082 0.182299586005621 0.8553476235605106 1.0 1.0 2 P10644 1
Rhob gtpase cycle 0.2654553617285163 0.1817498622779672 0.8557790331548647 1.0 1.0 26 O75116,Q86VI3,Q8TAA9 3
Signaling by notch1 0.3195147947562622 0.1791175592580494 0.8578453946772835 1.0 1.0 9 P63208,Q13573,Q92542 3
Heme biosynthesis 0.3987336481468598 0.1625275430775902 0.8708904403754916 1.0 1.0 4 P50336 1
Rhov gtpase cycle 0.2757117887686974 0.1623321766624811 0.8710442774005676 1.0 1.0 18 Q13153,P06753,O43396,Q8TAA9 4
Toll like receptor 9 tlr9 cascade 0.2625600861403234 0.1599864639155648 0.8728917370994778 1.0 1.0 20 Q14738,P30153,P05067,Q16539,P28482,P63208,P30154 7
Degradation of gli1 by the proteasome 0.2609066410740595 0.157855017169751 0.8745710446472359 1.0 1.0 39 Q92530,P49721,Q9UL46 3
Hemostasis 0.2287905558810891 0.1552599422585224 0.8766163940564102 1.0 1.0 131 Q8NBX0,Q96N67,P08195,Q9H4M9,O94919,O43852,Q8NCG7,Q13509,P46108,Q9NSK0,Q96JJ7,Q8NBM8,Q13362,P07602,P33176,Q07866,P04350,Q14185,P30153,P52732,Q9NTK5,P30154,P42785 23
Signaling by csf3 g csf 0.3353036741218906 0.151933139759967 0.8792396699568665 1.0 1.0 7 Q15369,P42224,P40763 3
Processive synthesis on the lagging strand 0.2868056943509746 0.1517377556208479 0.8793937772716827 1.0 1.0 14 Q9Y2S7,Q14181 2
Clec7a dectin 1 signaling 0.249639175241528 0.1471908166032595 0.8829814089383659 1.0 1.0 49 O43865,Q92530,P25787,P49721,Q9UL46 5
Met promotes cell motility 0.3208962188740152 0.1445188293973587 0.8850907888192145 1.0 1.0 8 Q96N67,P46108 2
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.4912334666256666 0.1387250698066174 0.8896674068042769 1.0 1.0 2 P17931 1
Anti inflammatory response favouring leishmania parasite infection 0.2765878318754703 0.1373678325340019 0.8907400558978562 1.0 1.0 12 Q9UBI6,Q16539,O43865,P19174 4
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3179903361821625 0.1361301534321202 0.8917183904153168 1.0 1.0 8 Q13573,P28482 2
Gap junction trafficking and regulation 0.2901754150811833 0.1351154986251362 0.8925205564175431 1.0 1.0 11 P04350,P50570,Q13509,Q9BUF5 4
Dna damage reversal 0.3852177838557261 0.1346878201038615 0.8928587035844788 1.0 1.0 4 Q6P6C2,Q9H1I8 2
Infection with mycobacterium tuberculosis 0.2882184750363112 0.1286569212293939 0.89762912390367 1.0 1.0 11 Q9UI12,P23246 2
Response of mtb to phagocytosis 0.2882184750363112 0.1286569212293939 0.89762912390367 1.0 1.0 11 Q9UI12,P23246 2
Ubiquinol biosynthesis 0.482313134420191 0.1253302464676818 0.9002621077450668 1.0 1.0 2 Q86YH6 1
Mitochondrial trna aminoacylation 0.2670788253477553 0.1252576092386934 0.9003196107352329 1.0 1.0 18 Q5JPH6,Q15046,Q9UGM6,Q6PI48,Q9HA77,Q9NSE4,Q9Y2Z4,P47897,P26640,Q96GW9,Q5JTZ9,P41250,Q5ST30,Q15031,Q9BW92,Q9H2U2,Q5T160 17
Rap1 signalling 0.4780067671485787 0.1192347925136892 0.9050893428176277 1.0 1.0 2 P31946 1
Cytosolic sensors of pathogen associated dna 0.2536343952984893 0.1188233336795793 0.9054153220444616 1.0 1.0 20 Q9NW08,P49959,P13010,P12956,P78527,Q08211,P62875,O15111,P19474,Q13546,O14802,Q9UJV9,O14920,P35222,Q13049,P61218,Q9H2U1,Q9NZI8,P19388 19
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.2436327225784899 0.1161915476728017 0.9075007353614636 1.0 1.0 50 Q15056,P46783,P08708,P62266,O75821,Q14240,Q9Y262,P23588,P23396,P62847,O00303,O15372,P62841 13
Deadenylation of mrna 0.2751414628387007 0.1154416509401295 0.9080950669474512 1.0 1.0 16 O95628 1
Negative regulation of notch4 signaling 0.2534235476680668 0.1126983101562511 0.9102697410154434 1.0 1.0 40 Q92530,P49721,Q9UL46 3
Activation of smo 0.4712396185789066 0.1101376234100119 0.9123002304781797 1.0 1.0 2 P48729 1
Protein folding 0.2535306070076535 0.1100481124180403 0.9123712184080176 1.0 1.0 37 P78371,P67870,Q13509,P40763,P04350,Q9UBI6,O60925,P36404,Q99471,Q15813,Q9UHV9,Q9Y2T2,P61758,Q99832,Q9BUF5 15
Phenylalanine and tyrosine metabolism 0.3700420912382189 0.1067525449278892 0.914985295914526 1.0 1.0 4 O43708,P61457 2
Wax and plasmalogen biosynthesis 0.3699803870710971 0.1066461655356501 0.9150696926014916 1.0 1.0 4 O00116 1
Stat3 nuclear events downstream of alk signaling 0.3699599876885249 0.1066110093575902 0.9150975841629116 1.0 1.0 4 Q13547,Q96ST3,P40763 3
Transcriptional regulation by runx3 0.2513480767302027 0.1060682119163669 0.9155282320516572 1.0 1.0 42 P20618,P61289,Q06323,O00487,Q92530,P25787,P49721,Q9UL46,P25440,P42771,Q13573 11
G protein beta gamma signalling 0.3440921681898378 0.1050648290213558 0.9163243671759924 1.0 1.0 5 Q13153 1
C type lectin receptors clrs 0.2378757090709987 0.1011243630734141 0.9194517382419976 1.0 1.0 52 O43865,Q92530,P25787,P49721,Q9UL46,Q9UDY8 6
Regulation of runx3 expression and activity 0.2519311395030175 0.1008329624819559 0.9196830599049322 1.0 1.0 38 Q92530,P49721,Q9UL46 3
Rhof gtpase cycle 0.2598107804390263 0.0962393111602733 0.9233305099085076 1.0 1.0 18 Q8TAA9,Q07960 2
Signaling by met 0.2483494875578744 0.0960758572127971 0.9234603257431696 1.0 1.0 20 Q96N67,P46108,Q96P70 3
G protein mediated events 0.2767348728352526 0.092927748659136 0.9259609608842952 1.0 1.0 11 O43865,P28482 2
Dap12 signaling 0.3613419513696581 0.0923275535344603 0.926437797306526 1.0 1.0 4 O00459,P62993,P19174 3
Downstream signaling events of b cell receptor bcr 0.2482452690410269 0.0910963709164936 0.9274160162437606 1.0 1.0 43 Q92530,P25787,P49721,Q9UL46 4
Sumoylation of transcription factors 0.336514778325114 0.0905027203506742 0.9278877322992816 1.0 1.0 5 Q12888,P42771,Q13330,P04637 4
Mtor signalling 0.2657950888808127 0.088961210593626 0.9291127373098308 1.0 1.0 13 P31751,P23588,P54619,P54646,P42345 5
Synthesis of udp n acetyl glucosamine 0.359170011311872 0.0889062526494794 0.9291564143376104 1.0 1.0 4 Q06210 1
Circadian clock 0.2822690857886077 0.0879586037497495 0.9299095779898 1.0 1.0 10 Q7Z5J4,P43490,P50416,Q86X55 4
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.2881941645137522 0.0855261373547575 0.9318431169911264 1.0 1.0 9 A0AVT1,P49427 2
Met activates ras signaling 0.35363675426379 0.0805124533685884 0.9358296920336848 1.0 1.0 4 Q96P70 1
Apoptotic factor mediated response 0.3133269502491476 0.0803209560348648 0.9359819915536584 1.0 1.0 6 P42771,P28482 2
Interferon alpha beta signaling 0.2844068421937625 0.0758459229409875 0.93954168009713 1.0 1.0 9 P10321,P42224 2
Lipophagy 0.3455560745718843 0.0690778410111867 0.9449276591989232 1.0 1.0 4 P54646 1
Translocation of slc2a4 glut4 to the plasma membrane 0.2449421138656849 0.0685119762789078 0.9453780867859832 1.0 1.0 33 Q8IYI6,Q13509,P31751,O60645,P04350,Q86YS7,P54619,O60343,Q96KP1,P35579,P54646,O00471,Q9UPT5,Q9BUF5 14
Signaling by erbb4 0.2993776341692462 0.0647046058809581 0.9484091955472556 1.0 1.0 7 P46934 1
Enos activation 0.4255384615384645 0.063821873048879 0.9491120615876458 1.0 1.0 3 P07900,P35270 2
Neddylation 0.2308178423849125 0.0631958379003116 0.949610559031206 1.0 1.0 78 P20618,Q15369,Q13617,P25787,Q9Y6G5,Q92564,Q9Y5A7,P61289,Q96GG9,Q06323,Q92530,Q9H0A8,Q99627,Q9UBW8,Q15345,P49721,Q7L5N1,O00487,Q9UL46 19
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4226662827860933 0.0611251058433443 0.9512595749592034 1.0 1.0 3 P52292 1
Signaling by notch1 pest domain mutants in cancer 0.2973555150612778 0.0605980355791953 0.9516793380315473 1.0 1.0 7 Q13573,Q92542 2
Activation of bh3 only proteins 0.2707279961775296 0.0579425303324319 0.9537944057031876 1.0 1.0 10 P31751,Q96FJ2 2
Class b 2 secretin family receptors 0.415564441710248 0.0559512305225845 0.9553806586620548 1.0 1.0 2 Q9UBI6 1
Notch1 intracellular domain regulates transcription 0.2942082563154716 0.0543782049862352 0.9566338430592412 1.0 1.0 7 Q13547,Q92769,P63208,Q13573,Q04726,P24863 6
Irak1 recruits ikk complex 0.4104615384615435 0.0506109109492173 0.9596355682891275 1.0 1.0 3 O14920,O15111 2
Tnfr2 non canonical nf kb pathway 0.2413663243085841 0.0449546062730399 0.9641434912934312 1.0 1.0 41 Q92530,P49721,Q9UL46 3
Dectin 1 mediated noncanonical nf kb signaling 0.2413663243085841 0.0449546062730399 0.9641434912934312 1.0 1.0 41 Q92530,P49721,Q9UL46 3
Attachment of gpi anchor to upar 0.3251482556407046 0.0444186717143776 0.9645706784611692 1.0 1.0 4 Q96S52,O43292 2
Signaling by kit in disease 0.3023862137477605 0.0372773332004632 0.9702638784145192 1.0 1.0 5 P42224,P40763 2
Interleukin 37 signaling 0.3780375269148007 0.036641797030835 0.9707706166807216 1.0 1.0 2 P40763 1
Signaling by leptin 0.3780375269148007 0.036641797030835 0.9707706166807216 1.0 1.0 2 P40763 1
Fceri mediated mapk activation 0.2841067666656366 0.0358207752780155 0.9714252674199542 1.0 1.0 7 Q13153,P28482 2
Foxo mediated transcription 0.2657213316892735 0.03342371295922 0.9733367000177504 1.0 1.0 9 Q13547,Q92769,P63104,P31751,P61981,P04179,P31946,Q96ST3 8
Nef and signal transduction 0.3611196554906217 0.0312293426451857 0.975086639275058 1.0 1.0 2 Q13177 1
Oas antiviral response 0.3793846153846101 0.0301612838530365 0.9759384254828972 1.0 1.0 3 P21333,P61221 2
Tie2 signaling 0.3781538461538454 0.0295200394924883 0.9764498367015078 1.0 1.0 3 O00459,P62993 2
Downstream signaling of activated fgfr4 0.3781538461538427 0.0295200394924872 0.9764498367015086 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr3 0.3781538461538427 0.0295200394924872 0.9764498367015086 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr1 0.3781538461538427 0.0295200394924872 0.9764498367015086 1.0 1.0 3 P62993,P19174 2
Downstream signaling of activated fgfr2 0.3781538461538427 0.0295200394924872 0.9764498367015086 1.0 1.0 3 P62993,P19174 2
Rho gtpases activate rocks 0.2562502204473738 0.0254283845037245 0.9797132708643116 1.0 1.0 10 O75116 1
Fbxw7 mutants and notch1 in cancer 0.2937557674561675 0.0217570982460714 0.982641716717982 1.0 1.0 2 P63208 1
Regulation of beta cell development 0.3601082966037426 0.0213986540475046 0.9829276472353464 1.0 1.0 3 P31751 1
Phospholipid metabolism 0.2298414122368265 0.0191000084531522 0.9847613246873356 1.0 1.0 49 P67870,Q9UG56,Q9C0I1,Q9HCL2,Q9NPH0,P48651,Q10713,Q8IV08,P35790 9
Map3k8 tpl2 dependent mapk1 3 activation 0.2939365958756591 0.0174198434669792 0.9861016787594384 1.0 1.0 4 O14920,O15111,P63208 3
Fceri mediated nf kb activation 0.2337828963753408 0.0170852953514357 0.9863685698112614 1.0 1.0 45 Q92530,P25787,P49721,Q9UL46 4
Deadenylation dependent mrna decay 0.2363059403676268 0.0163586415855864 0.986948274563916 1.0 1.0 39 Q9Y450,Q96F86,O95628,Q5TAX3,Q14240,Q9GZS3,P23588,Q9Y2L1,P26196,Q6PGP7,Q96C86 11
Mrna decay by 3 to 5 exoribonuclease 0.2469021922362742 0.0148193904960322 0.988176269901061 1.0 1.0 15 Q9Y450,Q9GZS3,Q9Y2L1,Q6PGP7,Q96C86 5
Tcr signaling 0.2256710526018291 0.0118954885111723 0.9905089972079252 1.0 1.0 51 P20618,P25787,O43242,Q13200,P61289,Q06323,Q92530,O00459,P63208,P62333,P49427,Q13177,P49721,Q9UDY8,Q99436,O00487,P19174,O00231,Q9UL46,P62195,P28074,P60900,Q13153 23
Folding of actin by cct tric 0.2619414483821164 0.0118329612359456 0.9905588832443508 1.0 1.0 8 P78371,P50991,P48643,P50990,P49368,P17987,Q99832 7
Role of abl in robo slit signaling 0.2786330049260967 0.0115004363023565 0.990824181697974 1.0 1.0 5 O75122,Q9Y6N7,O94813,Q7Z460 4
Formyl peptide receptors bind formyl peptides and many other ligands 0.3170832938629967 0.0098455564666978 0.9921445094148872 1.0 1.0 3 Q9NRV9 1
Rora activates gene expression 0.3125886683717893 0.0091198618063805 0.9927235039348152 1.0 1.0 3 Q86X55 1
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.2421968732234022 0.0085815107631766 0.9931530290916126 1.0 1.0 11 Q9UI12,O43747,Q9BXS5 3
Interleukin 7 signaling 0.3083076923076872 0.0084935383800509 0.9932232183397928 1.0 1.0 3 O00459,P40763 2
Activation of bad and translocation to mitochondria 0.2655576093653788 0.0072090246667033 0.9942480803412794 1.0 1.0 7 P63104,Q04917,P31751,P61981,P31946,P62258 6
Piwi interacting rna pirna biogenesis 0.2466139129278734 0.0069287243527736 0.9944717220457756 1.0 1.0 10 Q9Y2W6 1
Prolactin receptor signaling 0.2938461538461505 0.0067889809245826 0.9945832185468684 1.0 1.0 3 P63208,Q06124 2
Regulation of bach1 activity 0.2938461538461474 0.006788980924582 0.9945832185468688 1.0 1.0 3 P63208,Q13309 2