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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Oxidation by cytochrome p450 0.779828015425275 2.5530920540971698 0.0106771272929133 0.9982239735270992 0.7580817464246714 6 Q16850 1
Familial partial lipodystrophy fpld 0.775627476791027 2.4934397769561363 0.0126512043484166 0.9994534191021638 0.7580817464246714 8 P49354,P02545,O75844,O60725,Q03252,P31751 6
Striated muscle contraction pathway 0.7652421744106582 2.4897035676160897 0.0127849679143781 0.9994954105269488 0.7580817464246714 6 P28289,P09493,P08670,P67936 4
Statin inhibition of cholesterol production 0.7435789057358764 2.3945360324361293 0.0166414082405494 0.999949877720375 0.7580817464246714 6 Q8WTV0 1
Sphingolipid metabolism overview 0.7578193183454702 2.3541458425234443 0.0185653254372715 0.9999842157237632 0.7580817464246714 11 Q96G23,P27544,Q06136,Q16739 4
Sphingolipid metabolism integrated pathway 0.7578193183454702 2.3541458425234443 0.0185653254372715 0.9999842157237632 0.7580817464246714 11 Q96G23,P27544,Q06136,Q16739 4
Copper homeostasis 0.7334020058823573 2.349402552548752 0.0188035653536873 0.9999863221683016 0.7580817464246714 6 P05067,Q8N668,O43819 3
Allograft rejection 0.7089125487673378 2.1768331818234077 0.0294930163145068 0.9999999786591222 0.7580817464246714 9 P08183,Q9BY49,P08670,P10321 4
Mitochondrial complex iv assembly 0.6972697664569524 2.103261608967153 0.0354429074033995 0.9999999994331294 0.7580817464246714 10 Q8N8Q8,Q9Y2R0 2
Sphingolipid metabolism in senescence 0.6985459713969133 2.047723847349327 0.0405870658002893 0.9999999999758294 0.7580817464246714 13 Q96G23,O15121,Q06136,Q16739 4
Omega3 omega6 fatty acid synthesis 0.6641107938807143 2.03475225531917 0.0418758073443972 0.999999999989064 0.7580817464246714 6 O15254 1
Praderwilli and angelman syndrome 0.6609778791244603 1.998993726255182 0.0456090326765856 0.9999999999989072 0.7757048339404323 7 Q15154,Q7L576,P11802 3
Progeriaassociated lipodystrophy 0.6660255031916761 1.9595924902171211 0.0500434398349622 0.99999999999993 0.7757048339404323 10 P49354,P02545,O75844,O60725,Q03252 5
Metabolism of spingolipids in er and golgi apparatus 0.6434399561973831 1.9383950397233385 0.0525750451353304 0.9999999999999856 0.7757048339404323 6 Q16739,Q06136,O95470 3
Acquired partial lipodystrophy barraquersimons syndrome 0.8504043126684551 1.8570244081905247 0.0633076815638808 1.0 0.8276830462911419 5 O60725,P49354,P02545,Q03252 4
Sphingolipid pathway 0.6385672505907531 1.8105764963453712 0.0702064331770011 1.0 0.8276830462911419 11 Q96G23,Q06136 2
Genes related to primary cilium development based on crispr 0.6285992065332837 1.8050923019955167 0.0710602394846013 1.0 0.8276830462911419 9 Q10713,O95684 2
P53 transcriptional gene network 0.6136430678545047 1.7762182970501543 0.0756969436101377 1.0 0.8276830462911419 7 P30038,P04066 2
Influence of laminopathies on wnt signaling 0.6215844304830509 1.7718458253289324 0.0764201533091299 1.0 0.8276830462911419 9 O60725,P49354,P02545,O75844 4
Nanomaterial induced apoptosis 0.8276977875669774 1.7651240521641656 0.0775429191556145 1.0 0.8276830462911419 5 O95831,O43464 2
Cholesterol biosynthesis with skeletal dysplasias 0.8223014362741878 1.743184250871762 0.0813014355683421 1.0 0.8276830462911419 5 Q14739,Q16850 2
Ciliopathies 0.6518468992137179 1.7318373952091892 0.0833025179389044 1.0 0.8276830462911419 18 Q10713,Q13432,O43924 3
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6286342964095244 1.7226900492014514 0.0849445907661152 1.0 0.8276830462911419 13 P49354,P55209,O75844,P02545,O60725 5
Ketogenesis and ketolysis 0.5850545777219127 1.6602360883960814 0.0968669672906084 1.0 0.8276830462911419 6 P53985,O43772 2
Folate metabolism 0.612205041605686 1.6446416256034853 0.1000437374146623 1.0 0.8276830462911419 13 P00374,P34896,P41440,P22102,Q99707,Q8WTV0 6
Degradation pathway of sphingolipids including diseases 0.5750460098009047 1.6117105518947223 0.1070249404336822 1.0 0.8276830462911419 6 P16278,P06865,P06280 3
Joubert syndrome 0.6240296298153589 1.6007942191074145 0.1094225044249306 1.0 0.8276830462911419 18 Q10713,Q13432,O43924,O15078 4
Apoptosis modulation and signaling 0.5874874311910527 1.567062050454678 0.1171001885009477 1.0 0.8473104491482761 11 O95831,O43464,Q9NR28 3
Cholesterol biosynthesis pathway 0.5948491606750541 1.5615638638115958 0.1183907679369959 1.0 0.8473104491482761 13 P37268,Q16850 2
Adipogenesis 0.5925893000898969 1.5507015250273972 0.1209732288941578 1.0 0.8481979389378371 13 P14174,P02545,P43490 3
Triacylglyceride synthesis 0.7740758946009125 1.5456132132774711 0.1221980081520612 1.0 0.8481979389378371 5 Q9NUQ2,Q9HCL2 2
Methionine de novo and salvage pathway 0.5686802492823588 1.517420685118033 0.1291605046803501 1.0 0.884234487473592 9 Q9UHY7,Q13126,Q99707 3
Nephrotic syndrome 0.568550948330283 1.4960035979670443 0.1346527175771537 1.0 0.884234487473592 10 Q14108,P02545,O75844 3
Ccl18 signaling pathway 0.555078241241858 1.4510516546353445 0.1467654771569027 1.0 0.9107324124191256 9 P07196,P08670 2
Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.5262980445043743 1.3512364751244923 0.1766196938296031 1.0 0.969639188799613 7 P35222,P35221,P05556,Q13043,Q13177,P27348 6
Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.515776615220983 1.2782455330227611 0.2011628659751974 1.0 0.976603454928959 8 Q9UHD1,Q9Y6K9,P11802,P62993 4
Irinotecan pathway 0.8895994614607794 1.197643554973896 0.2310558122812755 1.0 0.976603454928959 2 O15118 1
Complement system in neuronal development and plasticity 0.5029730003962908 1.1941621664398177 0.2324145393148895 1.0 0.976603454928959 9 O43464,Q5KU26,Q16611,Q9NR28 4
Glycosaminoglycan degradation 0.6781213353694826 1.1476568085893093 0.2511102680580834 1.0 0.976603454928959 5 P54802,P16278,P06865 3
Type ii interferon signaling ifng 0.4765864214048924 1.12444273438734 0.2608252514363722 1.0 0.976603454928959 6 Q03518,P01889 2
Eicosanoid metabolism via lipooxygenases lox 0.6663618435535592 1.098894511396585 0.2718140809732627 1.0 0.9838669188602764 5 P09960,O15254 2
Type i collagen synthesis in the context of osteogenesis imperfecta 0.4947813370886807 1.093253991358745 0.2742822974079679 1.0 0.9857229226608868 12 Q32P28,P13674,Q96AY3 3
Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4853244231176912 1.0270806980636535 0.3043824666991495 1.0 1.0 13 O15372,O75822,P55010,O00303 4
Cholesterol metabolism with bloch and kandutschrussell pathways 0.5268524615269724 1.021016407528619 0.307246665216291 1.0 1.0 24 P48449,P37268,Q16850,Q15800,Q14739,Q9BWD1,Q15392 7
Vitamin d receptor pathway 0.4822391119726072 1.0119396698232597 0.3115669002397767 1.0 1.0 13 Q92604,Q96KA5,P09493,P08183 4
Sterol regulatory elementbinding proteins srebp signaling 0.550583573616778 1.0090539209463507 0.3129487751535953 1.0 1.0 31 Q8WTV0,Q16850,Q9HCL2 3
Myometrial relaxation and contraction pathways 0.4954525063637822 0.9996472843533616 0.3174812316872193 1.0 1.0 17 P78417,Q05682,Q13555,P16615,P10644,P13861 6
Zinc homeostasis 0.8668091983789556 0.9933775477806848 0.3205259989878761 1.0 1.0 3 Q6NXT4 1
Mitochondrial complex i assembly model oxphos system 0.5258271245476365 0.962227514475284 0.3359353308500377 1.0 1.0 27 P03886,Q96CU9,O43676,O75438,O96000,P51970,O75380,Q8IUX1,O43674 9
Glycogen synthesis and degradation 0.4905875574726374 0.9572568921100169 0.3384376077426045 1.0 1.0 18 Q16537,P63151,P30154,P46976 4
Eicosanoid synthesis 0.8306967351060192 0.9505699831862932 0.3418227122494341 1.0 1.0 2 P09960 1
Metapathway biotransformation phase i and ii 0.4950670563489952 0.941761925999882 0.3463145422615992 1.0 1.0 20 P78417,Q86UY6,Q16850,Q7LGA3,P07099 5
Spinal cord injury 0.4796230711658926 0.9416897639167428 0.3463514972117556 1.0 1.0 16 Q08722,P14174,P62942,P08670 4
Congenital generalized lipodystrophy cgl 0.8283406260518247 0.9408945265964186 0.3467589128054671 1.0 1.0 2 P31751 1
Wnt signaling pathway and pluripotency 0.463637870454227 0.9208663449771124 0.3571202115086951 1.0 1.0 13 Q16537,P63151 2
Dna mismatch repair 0.4889060698725815 0.9121667258892204 0.3616809570435275 1.0 1.0 20 P41440 1
Estrogen receptor pathway 0.8411530668776219 0.8983139354789448 0.3690182051989348 1.0 1.0 3 Q9HCL2 1
Tlr4 signaling and tolerance 0.8319865319865382 0.8647861811493031 0.387156157195925 1.0 1.0 3 Q15629,Q9Y6K9 2
Pilocytic astrocytoma 0.8044429485021858 0.8439811845229027 0.3986799198214708 1.0 1.0 2 P62993 1
Cellular proteostasis 0.7935331761535865 0.8345685114297939 0.4039606976532304 1.0 1.0 4 P61758,Q9UHV9,O15212 3
Arrhythmogenic right ventricular cardiomyopathy 0.4435890808900324 0.823394831824681 0.4102835010902184 1.0 1.0 13 P12814,P50402,P02545,P35221,O43707 5
Nucleotide excision repair 0.4802504149017882 0.7995846730377408 0.4239514705661225 1.0 1.0 24 P54725 1
Mitochondrial complex iii assembly 0.42107306701499 0.789536325508196 0.4297986073272466 1.0 1.0 9 P22695,Q9UDW1 2
Erbb signaling pathway 0.4316363495071056 0.7475316835108489 0.4547426850995273 1.0 1.0 14 Q13555 1
Fas ligand pathway and stress induction of heat shock proteins 0.4256571778568742 0.737216332600852 0.4609908027259304 1.0 1.0 13 P20700,P02545,Q9UNN5,Q9UER7,Q13813,Q03252 6
Urea cycle and related diseases 0.7650622685964241 0.6903149067585322 0.4899961755574435 1.0 1.0 2 Q9Y619 1
Pdgfrbeta pathway 0.387259858442858 0.6822972513071105 0.4950510107791519 1.0 1.0 6 P19525,P19174,P42224,P05771,P62993 5
Regulation of sister chromatid separation at the metaphaseanaphase transition 0.399708964524274 0.6682970228331319 0.5039440133734563 1.0 1.0 10 O60566 1
Male infertility 0.4287040479962679 0.6457579795219406 0.5184361052502864 1.0 1.0 19 P41440,P08183 2
Omega9 fatty acid synthesis 0.3724300640377533 0.6116312370455547 0.5407817661715915 1.0 1.0 6 O95864,P49327,O00767,O95573,P33121 5
Nocgmppkg mediated neuroprotection 0.7255313600273903 0.6089333696016368 0.5425686046364586 1.0 1.0 4 Q13555 1
Histone modifications 0.7239883380935639 0.6040303788900822 0.5458234450633803 1.0 1.0 4 Q9H7B4 1
Small cell lung cancer 0.3784730133272599 0.5691211337186262 0.5692739371956872 1.0 1.0 10 Q9Y6K9,P11802,Q16611,P31751 4
Vitamin a and carotenoid metabolism 0.7026730695356079 0.5375420707322079 0.5908932326584888 1.0 1.0 4 Q8WTV0,P09455 2
Primary focal segmental glomerulosclerosis fsgs 0.3967205879251947 0.5179581595083084 0.6044874621292968 1.0 1.0 18 Q14108 1
Ferroptosis 0.421616720410392 0.5163855436726122 0.6055851604809912 1.0 1.0 25 P37268,P45880 2
Calcium regulation in cardiac cells 0.4096566696369149 0.4955570006330421 0.6202069966922195 1.0 1.0 23 P62942,Q13555,P16615,Q14012,P10644,P13861 6
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.7191919191919252 0.4823843542637673 0.6295329334689543 1.0 1.0 3 P09601,Q9Y6K9 2
Eicosanoid metabolism via cyclooxygenases cox 0.5070888233222498 0.4729117760421181 0.6362761230606226 1.0 1.0 5 O15254 1
Cysteine and methionine catabolism 0.3413179146372035 0.468921137058155 0.6391260072007499 1.0 1.0 6 Q99707,P25325,P23526 3
1q211 copy number variation syndrome 0.3483076745225652 0.4506362476657048 0.6522517373993297 1.0 1.0 9 P55196,P54646,Q16625,Q9NPH0,P54619 5
Proteoglycan biosynthesis 0.6702315716138401 0.4414089681307819 0.6589169508956545 1.0 1.0 4 Q9NX62 1
Parkinsons disease pathway 0.3308855560338563 0.407421786901518 0.683698227979318 1.0 1.0 7 O43464 1
Apoptosis 0.3418176160755847 0.4070259696531321 0.6839889145497486 1.0 1.0 10 Q9NR28 1
Ebola virus infection in host 0.4318701858007638 0.3989307189453965 0.6899442536476743 1.0 1.0 36 P07858,Q9H269,P41440,O15118 4
Physicochemical features and toxicityassociated pathways 0.3385531058632521 0.3633434852566385 0.7163483131884849 1.0 1.0 12 P07196,P07197,P62993 3
Splicing factor nova regulated synaptic proteins 0.34366367715273 0.3405128438077356 0.733470352110333 1.0 1.0 15 P11171,Q13555,Q06481 3
Oxidative phosphorylation 0.3991297093600255 0.3244051067809406 0.7456313539782768 1.0 1.0 32 P00846,P03886,O75438,O96000,P51970,O75380,O75964,O43674 8
Familial hyperlipidemia type 1 0.6506226859643073 0.3132691594939832 0.7540761788864729 1.0 1.0 2 Q9UBV2 1
Familial hyperlipidemia type 5 0.6506226859643073 0.3132691594939832 0.7540761788864729 1.0 1.0 2 Q9UBV2 1
Cardiac hypertrophic response 0.3107442016863899 0.3103048312285513 0.7563291575782545 1.0 1.0 8 P31751 1
Tolllike receptor signaling pathway 0.3103081806531014 0.3086082874594381 0.7576195159178294 1.0 1.0 8 Q9Y6K9,P31751 2
Amyotrophic lateral sclerosis als 0.3209629430888366 0.3079341302840179 0.7581324546167694 1.0 1.0 11 P07196,Q9UER7 2
Tcell receptor tcr signaling pathway 0.3304611328631979 0.3030946495046477 0.7618177315686001 1.0 1.0 14 Q9Y6K9,Q9UJU6,P08670,P62993 4
Head and neck squamous cell carcinoma 0.3293797217335603 0.2989750906112303 0.7649590515905897 1.0 1.0 14 P31751 1
Intracellular trafficking proteins involved in cmt neuropathy 0.3025609651910101 0.2656216996338014 0.7905305718842488 1.0 1.0 9 P07196 1
G protein signaling pathways 0.3168623791933879 0.2655894487892081 0.7905554124918814 1.0 1.0 13 O43823,Q02952,Q92888 3
Disorders of folate metabolism and transport 0.2899391075976422 0.2458295399406833 0.8058141890411512 1.0 1.0 7 P22102,Q99707 2
Resistin as a regulator of inflammation 0.4347513658592117 0.2443247688087529 0.8069793019126208 1.0 1.0 5 P31751 1
Proteasome degradation 0.4018123349036105 0.2134821092081814 0.8309509422717523 1.0 1.0 42 P49720,P01889,P28070,P49721,P10321,P20618,P28074,Q99436,Q9UL46,P28072,P28066 11
Neural crest differentiation 0.2744436952124105 0.192530424264346 0.8473267385594285 1.0 1.0 7 P56545,P35222,Q13547,P05556,P19022,Q9NR77 6
Angiopoietinlike protein 8 regulatory pathway 0.3283417433874306 0.1734780180931801 0.862275704932612 1.0 1.0 24 P41440 1
Nucleotide excision repair in xeroderma pigmentosum 0.3555969280644167 0.1727270199494551 0.8628660041541782 1.0 1.0 32 P54725 1
Modulators of tcr signaling and t cell activation 0.2821283752442458 0.1715637922931588 0.8637804748786979 1.0 1.0 11 O96000,Q9Y6K9 2
Sarscov2 innate immunity evasion and cellspecific immune response 0.2741541747167526 0.1579231492230407 0.8745173565164965 1.0 1.0 10 P35613 1
Vitamin d metabolism 0.5836797143420678 0.1549088548072292 0.8768931727919791 1.0 1.0 3 P04062 1
Apoptosisrelated network due to altered notch3 in ovarian cancer 0.2910791514868021 0.1451518362494407 0.8845909922065218 1.0 1.0 16 P08670 1
Pathways of nucleic acid metabolism and innate immune sensing 0.3921718901840724 0.1404989933254647 0.888265747811638 1.0 1.0 5 Q9Y3Z3,O00584 2
Hepatitis c and hepatocellular carcinoma 0.2630984851099281 0.1357916154274839 0.8919860195834555 1.0 1.0 9 P31350,P62993 2
Tp53 network 0.5624368899360329 0.1292099489969425 0.8971915240431778 1.0 1.0 2 P42771 1
Regulation of actin cytoskeleton 0.3478355506902852 0.1290081227960582 0.8973512214806969 1.0 1.0 34 P35580,P12814,Q9UJX6,Q9UQB8,O14974,Q92888,Q9NSV4 7
Mirnas involvement in the immune response in sepsis 0.5581974796775376 0.1157733827714726 0.9078321461071412 1.0 1.0 3 Q9Y6K9 1
15q112 copy number variation syndrome 0.379665553545293 0.1151147220426495 0.908354190975843 1.0 1.0 5 Q7L576,Q9UGJ1 2
Transcriptional activation by nrf2 in response to phytochemicals 0.5577205632693883 0.1151119171717401 0.9083564141603386 1.0 1.0 3 P09601 1
Dna damage response only atm dependent 0.2764885294854086 0.1139385878210399 0.9092864760757516 1.0 1.0 15 P31751 1
Mecp2 and associated rett syndrome 0.291264483432319 0.1063834063971982 0.9152781581377548 1.0 1.0 20 P52597,Q03518,P35637 3
Fatty acid transporters 0.3723045822102445 0.1012999452687453 0.9193123596409856 1.0 1.0 5 Q6P1M0,Q01469,O95573,P33121 4
Translation factors 0.3401142862649439 0.0892658722484774 0.9288706157618672 1.0 1.0 36 P55010,O75822,P23588,O15372,O00303,O75153 6
Dna replication 0.309055522172511 0.0890868281951419 0.9290129053478512 1.0 1.0 27 P41440 1
Glucocorticoid receptor pathway 0.2345803842264961 0.0886327064983015 0.9293738143397474 1.0 1.0 6 Q86UP2,Q13616,P07900,Q15185,P27105 5
Mrna protein and metabolite inducation pathway by cyclosporin a 0.5277684281386559 0.0857064845612539 0.9316997471651368 1.0 1.0 2 P08195 1
Hippoyap signaling pathway 0.5274318411309206 0.0853576161289471 0.9319770875679758 1.0 1.0 2 Q13043 1
Serotonin and anxietyrelated events 0.5109390777515865 0.0698596071614424 0.9443054033595883 1.0 1.0 2 P05771 1
Unfolded protein response 0.5033670033669948 0.0558468769356841 0.9554637907946936 1.0 1.0 3 P05198,P04637 2
Mitochondrial complex ii assembly 0.4823291820935602 0.0497212616095438 0.9603445130988464 1.0 1.0 2 P21912 1
Steroid biosynthesis 0.4772803769774261 0.046949955989264 0.9625531128429596 1.0 1.0 2 P51659 1
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3311994609164463 0.0393956414869486 0.9685749548032848 1.0 1.0 5 P61201,P18031,P06753,P22466 4
Cancer immunotherapy by pd1 blockade 0.477970618947996 0.0380161911737624 0.9696747726698516 1.0 1.0 3 Q06124 1
Measles virus infection 0.2682034253876894 0.036172309539856 0.9711449653209924 1.0 1.0 22 P54652,P0DMV9,P63244,P04637,Q9Y6K9,P40763,Q7Z434,P19525,P51151,P42224,P49327,P11142,P24941,P67870,P05198,P26038,P11802,Q00534,Q16611,O15372 20
Complement and coagulation cascades 0.4382362840794302 0.0318069078699826 0.974626037741551 1.0 1.0 2 P10909 1
Leptininsulin signaling overlap 0.3867384718949835 0.0234196672104845 0.9813155171426136 1.0 1.0 2 O14654 1
Micrornas in cardiomyocyte hypertrophy 0.2352154334526259 0.022248239635898 0.9822499374348752 1.0 1.0 15 Q9Y6K9,P31751 2
Interleukin1 induced activation of nfkb 0.3106698081454017 0.0208183880750608 0.9833905293548236 1.0 1.0 2 Q13501 1
Relationship between inflammation cox2 and egfr 0.4342755457853011 0.0186891662013958 0.9850890708658282 1.0 1.0 3 P31751 1
Vitamin b12 disorders 0.4117731631101181 0.0121378235028599 0.9903156558197426 1.0 1.0 4 Q99707 1
Electron transport chain oxphos system in mitochondria 0.3489961703308891 0.0074379458155113 0.994065432589482 1.0 1.0 49 P00846,P03886,O43676,Q9UDW1,P14406,O75438,O96000,P51970,O75964,O43674 10
Pyrimidine metabolism and related diseases 0.189079878665324 0.0043868981635667 0.996499772912385 1.0 1.0 6 Q05682,P04818,P31350,P11172,P27708 5
Hepatitis b infection 0.2462175947581862 0.0032923830080176 0.9973730631755592 1.0 1.0 21 Q15750,Q9Y6K9,P31751 3
Il10 antiinflammatory signaling pathway 0.3869989895587724 0.0026347269224174 0.9978977944988484 1.0 1.0 4 P42224,P09601,P53004 3
Tyrobp causal network in microglia 0.3792522734927571 0.000356730387664 0.9997153703373504 1.0 1.0 4 P61916,Q15758,Q15418 3