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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:de3d49950da4482bd3889bf8962842fac809201089ea85f91e9397d60089adb2
+size 69546

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.547169811320755
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C218/C218_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.6843818456625109	1.1521259895315237	0.249269304774794	0.9999997484286478	0.5149519961474227	4	P25705	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.6775496465836246	0.5802652605207154	0.5617357505040981	1.0	0.7756321270103178	3	Q9H3G5,Q9HB40	2
+Glycosyl hydrolases family 31, active site [IPR030458]	0.5390309555854734	0.0552345580775643	0.9559515975835424	1.0	0.9743352821524568	2	Q14697	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K2", "MAPK1", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ATP5A1", "CPVL", "GANAB", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2f8e9886994899039497d595647466dabc9f70675250cf598f4c569780e63525
+size 70621

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	14	36	2.496208431134774	0.0125528818097004	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0004220978336843	0.3013443292367993	0.1621375830183236	0.0087211924770031	0.0010060220636706
+Beta tubulin, autoregulation binding site [IPR013838]	3	6	2.256764425540956	0.0240227987418444	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	0.0003231317436263	1.0	1.0	1.0	0.0004821022681723

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.32258064516129
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C218/C218_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.5114181115313954	2.496208431134774	0.0125528818097004	0.3240271591844893	0.1005432673635467	36	Q6NUK1,Q9BPX6,P80303,Q9Y680,O95302,P43304,Q8IXI1,Q14257,Q9BRK5,Q96AY3,O95202,Q9NWM8,O43852,Q02818	14
+Beta tubulin, autoregulation binding site [IPR013838]	0.8182949698412658	2.256764425540956	0.0240227987418444	0.5294239132962782	0.1005432673635467	6	P68371,Q9BVA1,P07437	3
+Peptidase M16, zinc-binding site [IPR001431]	0.6406973434957853	1.342431970862462	0.179455974307201	0.997826505623716	0.3973668002516595	5	Q10713	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.648384925975778	0.1998274173550186	0.8416155578154279	1.0	0.8876776500450982	2	O75600	1
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6362718707940855	0.1775926628543982	0.8590428871404177	1.0	0.8876776500450982	2	P34897	1
+Protein kinase, ATP binding site [IPR017441]	0.2489221383387435	0.0760370630745747	0.9393896114669332	1.0	0.9393896114669332	41	Q15418,P31751,Q13555,P51812,P05771	5

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K2", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["AKT2", "CALU", "CAMK2G", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GPD2", "LETM1", "MICU1", "NUCB1", "NUCB2", "PMPCA", "PRKCB", "RCN2", "RHOT2", "RPS6KA1", "RPS6KA3", "SDF4", "SHMT2", "SLC25A24", "TUBB", "TUBB2B", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "2": "Bromodomain, conserved site [IPR018359]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b7eef44a7c75b45ad4ac68305cca6c59e2c708e282b4e0bc937b6f5d2536e82b
+size 79908

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	3	6	2.256764425540956	0.0240227987418444	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	0.0058135215491787	1.0	1.0	1.0	0.0083885750898941
+Intermediate filament protein, conserved site [IPR018039]	7	8	2.1421113189847203	0.0321845252835319	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.5373208787031438	1.0	1.0	1.0	0.2029162289962234
+Syntaxin/epimorphin, conserved site [IPR006012]	2	7	2.0163499045147626	0.0437633999380073	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0152443958126454	0.0571215030354878	0.006013537610014	0.0027409769521145	0.0201496410307031

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 270,
+    "title": "Average number of proteins per term",
+    "value": 2.6259259259259258
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C218/C218_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,37 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.8182949698412658	2.256764425540956	0.0240227987418444	0.9985916466533472	0.3218452528353199	6	P68371,Q9BVA1,P07437	3
+Intermediate filament protein, conserved site [IPR018039]	0.7656776803776089	2.1421113189847203	0.0321845252835319	0.9998541213572344	0.3218452528353199	8	P48681,P20700,P07197,P08670,P07196,Q16352,Q03252	7
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7531993150600368	2.0163499045147626	0.0437633999380073	0.9999943421968412	0.3400747755705477	7	O60499,Q9P2W9	2
+Mini-chromosome maintenance, conserved site [IPR018525]	0.7425671199158932	1.9074078796833345	0.0564677898008898	0.9999998471317564	0.3400747755705477	6	Q14566	1
+Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]	0.7486857802431928	1.8516131198313737	0.0640813977105461	0.9999999828493163	0.3400747755705477	5	P30084	1
+AMP-binding, conserved site [IPR020845]	0.7046299094099419	1.646198540146502	0.0997228897389868	0.9999999999995196	0.3958797389040782	5	P33121,O95573	2
+Tetraspanin, conserved site [IPR018503]	0.9084483338943056	1.4638674284751103	0.1432301744520938	1.0	0.4938290416635728	3	O43657,O60637	2
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.6163414287860085	1.342715350985267	0.1793641620491177	1.0	0.5834737801597807	7	P51648	1
+Thioredoxin, conserved site [IPR017937]	0.5584246286883007	1.3279841649984572	0.1841833381631086	1.0	0.5868007510632957	12	Q9H3N1,Q9H1E5	2
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8522383036014753	1.241519251860311	0.214413990721171	1.0	0.6224922311259805	3	Q8WWV3,Q8N4Q0	2
+Guanylate kinase, conserved site [IPR020590]	0.6811447811447778	1.138275772030295	0.2550053474596758	1.0	0.6513613059600641	4	Q92796,Q00013,Q9NZW5	3
+Haem oxygenase conserved site [IPR018207]	0.949865410497984	1.1194294530717894	0.2629569716653592	1.0	0.6513613059600641	2	P30519	1
+ABC transporter-like, conserved site [IPR017871]	0.4807336540962892	0.7258249219138079	0.4679461067865116	1.0	0.870035620260493	9	Q03518,P28288,P08183,P33527	4
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.4713423451451495	0.6121160592722719	0.5404609731118726	1.0	0.9006248698573965	7	P51648	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8034993270524932	0.6071858579902839	0.5437275763519789	1.0	0.9006248698573965	2	P40939	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.484674974738968	0.6028324444475792	0.5466201607851193	1.0	0.9006248698573965	5	Q9BZF1,Q9BZF3,Q96SU4,Q9H4L5	4
+Proteasome beta-type subunit, conserved site [IPR016050]	0.4593805316012244	0.5820470676737899	0.5605349776194226	1.0	0.9006248698573965	8	P28074,P49721,Q99436	3
+Chromo domain, conserved site [IPR023779]	0.4546985517009079	0.470884132004059	0.6377234801862663	1.0	0.9565852202793996	5	O14646,Q13185,P83916,P45973	4
+Sterol reductase, conserved site [IPR018083]	0.7493270524899168	0.4423879546332406	0.6582084939099566	1.0	0.9764631503059796	2	Q14739	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	1.0	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	1.0	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	1.0	2	P05067	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.3635033375635654	0.2034909826046908	0.8387512930822429	1.0	1.0	11	Q9Y394,Q06136,Q6YN16,Q8NBN7,Q53GQ0,Q6IAN0,Q9BTZ2	7
+Actin, conserved site [IPR004001]	0.5469538875799288	0.1977173824199683	0.8432661889819657	1.0	1.0	3	O96019,P61163	2
+Bromodomain, conserved site [IPR018359]	0.363329962925514	0.1429422846066739	0.8863357631607494	1.0	1.0	7	P51532,Q9BXF3,Q8WWQ0,Q86U86,P25440,Q9NRL2	6
+Ras GTPase-activating protein, conserved site [IPR023152]	0.5592193808882964	0.0728449494799578	0.9419295014330724	1.0	1.0	2	Q13576	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.5393674293405218	0.0554981823596558	0.9557415779871392	1.0	1.0	2	P50570	1
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.5390309555854734	0.0552345580775643	0.9559515975835424	1.0	1.0	2	Q14697	1
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.5346567967698623	0.0518958013883662	0.9586117197764484	1.0	1.0	2	P52907	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.4564119824974575	0.0449969569815594	0.9641097344762368	1.0	1.0	3	P01889,P04439	2
+Histidine triad, conserved site [IPR019808]	0.4979811574697201	0.0298365427476572	0.9761974148330128	1.0	1.0	2	Q9BX68	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.4409289801413583	0.0289485434832615	0.9769056297256686	1.0	1.0	3	Q5T8D3,Q9H3P7	2
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.3950201884253023	0.0062701177490875	0.9949972026339184	1.0	1.0	2	P25325	1
+Ribosomal protein S9, conserved site [IPR020574]	0.3657469717361992	0.0047724861509522	0.9961921214386182	1.0	1.0	2	P82933	1
+Ribosomal S11, conserved site [IPR018102]	0.3654104979811564	0.0047610139539868	0.9962012748234635	1.0	1.0	2	P82912	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.3213324360699821	0.0039180670805878	0.9968738427666144	1.0	1.0	2	P10644	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MKRN2", "MPI", "MPP1", "MPP6", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NAGA", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD3", "ACBD3", "ACBD5", "ACSL1", "ACSL3", "ACTL6A", "ACTR1A", "ALDH3A2", "APP", "BAZ1A", "BRD2", "CAPZA1", "CBX1", "CBX3", "CBX5", "CECR2", "CHD1", "DHRS4", "DHRS7", "DHRS7B", "DLG3", "DNM2", "ECHS1", "GANAB", "HADHA", "HINT2", "HLA-A", "HLA-B", "HMOX2", "HSD17B12", "HSDL2", "INA", "IQGAP2", "KDSR", "LBR", "LMNB1", "LMNB2", "MCM6", "MPP1", "MPP6", "MPST", "MRPS11", "MRPS9", "NEFL", "NEFM", "NES", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "PBRM1", "PHIP", "PRKAR1A", "PSMB2", "PSMB5", "PSMB7", "RDH13", "RTN4IP1", "SMARCA4", "STX10", "STX18", "TAP1", "TMX1", "TMX4", "TSPAN3", "TSPAN6", "TUBB", "TUBB2B", "TUBB4B", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Intermediate filament, rod domain [IPR039008]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "GOLD domain [IPR009038]", "3": "Phospholipid/glycerol acyltransferase [IPR002123]", "4": "Band 7 domain [IPR001107]", "5": "Target SNARE coiled-coil homology domain [IPR000727]", "6": "Sterile alpha motif domain [IPR001660]", "7": "Myb domain [IPR017930]", "8": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:0fdb6b1d5d087e5b8442e5d22d5c238d963003b6677ab773b829660b7fc915ef
+size 187322

interpro_domain/df_merge.tsv

@@ -0,0 +1,11 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-hand domain [IPR002048]	18	42	3.1688930162476163	0.001530207092343	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	6.746315084363306e-05	0.3651666660245503	0.2316260817293756	0.0073583221547536	0.000203459930077
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	5	2.3626116849436327	0.0181466726604115	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0034891506811043	1.0	1.0	0.0005834813758982	0.0046922603501138
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	5	2.3626116849436327	0.0181466726604115	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0034891506811043	1.0	1.0	0.0005834813758982	0.0046922603501138
+Tubulin/FtsZ, GTPase domain [IPR003008]	3	6	2.256764425540956	0.0240227987418444	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	0.0058135215491787	1.0	1.0	1.0	0.0083885750898941
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	3	6	2.256764425540956	0.0240227987418444	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	0.0046739564659834	1.0	1.0	1.0	0.0067689787549618
+Tim10-like [IPR004217]	3	5	2.245655817434681	0.0247260622459608	1.2005141388174807	2.5167095115681235	0.6297728943083764	0.3036466482483842	1.011959204869136	1.1903007636326162	1.51035532787006	0.2968335314780513	4.255111738942612e-05	1.0	1.0	0.1279696795450588	6.421040500142641e-05
+Intermediate filament, rod domain [IPR039008]	7	8	2.1421113189847203	0.0321845252835319	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.6102236109588419	1.0	1.0	1.0	0.2727350450315673
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	1.9878823580189264	0.0468247023310921	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0622606961952341	1.0	1.0	0.0871339734410158	0.0798668337702702
+Protein kinase, C-terminal [IPR017892]	3	6	1.9813790089790344	0.0475487859715939	2.0194174757281553	5.813106796116505	-0.2988592628930643	0.4464463186043645	1.2958528512612006	1.4996838042955702	1.115578313938598	0.314572943307665	0.0248033761897355	1.0	1.0	0.1232030911135247	0.0346518670939496
+ABC transporter type 1, transmembrane domain [IPR011527]	4	5	1.9755912778324236	0.0482010873032643	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	0.0227958344904956	0.0656212707428065	0.1285014195248721	0.0438593755968587	0.0299271429004367

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 2448,
+    "title": "Average number of proteins per term",
+    "value": 2.110294117647059
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C218/C218_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,185 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-hand domain [IPR002048]	0.5474401151328826	3.1688930162476163	0.001530207092343	0.97645439091092	0.3987771805318585	42	Q6NUK1,Q9BPX6,P80303,Q9Y680,O95302,P43304,Q9UJS0,Q8IXI1,Q14257,Q9BRK5,Q96AY3,O95202,Q8NF37,Q8IYU8,Q9NWM8,O43852,O75071,Q02818	18
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8622450909725108	2.3626116849436327	0.0181466726604115	1.0	0.3987771805318585	5	Q9NZ08,P55786	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8622450909725108	2.3626116849436327	0.0181466726604115	1.0	0.3987771805318585	5	Q9NZ08,P55786	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.8182949698412658	2.256764425540956	0.0240227987418444	1.0	0.3987771805318585	6	P68371,Q9BVA1,P07437	3
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.8182949698412658	2.256764425540956	0.0240227987418444	1.0	0.3987771805318585	6	P68371,Q9BVA1,P07437	3
+Tim10-like [IPR004217]	0.835697376795575	2.2456558174346815	0.0247260622459608	1.0	0.3987771805318585	5	Q9Y5J9,Q9Y5J6,Q9Y5J7	3
+Intermediate filament, rod domain [IPR039008]	0.7656776803776089	2.1421113189847203	0.0321845252835319	1.0	0.3987771805318585	8	P48681,P20700,P07197,P08670,P07196,Q16352,Q03252	7
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9016835016835032	2.066947200695997	0.0387391294120103	1.0	0.3987771805318585	4	Q15629,Q96G23,Q96CP7	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7783765577635562	1.9878823580189264	0.0468247023310921	1.0	0.3987771805318585	5	Q9HD20,P16615,P20020,P05023	4
+Protein kinase, C-terminal [IPR017892]	0.7583608605008944	1.9813790089790344	0.0475487859715939	1.0	0.3987771805318585	6	Q15418,P31751,P51812	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7756820478275509	1.9755912778324232	0.0482010873032643	1.0	0.3987771805318585	5	P28288,P33527,P08183,Q03518	4
+LEM domain [IPR003887]	0.7503369200904281	1.94387017888924	0.0519111081960248	1.0	0.4025491187325755	6	Q86XL3,P42167	2
+Ricin B, lectin domain [IPR000772]	0.7648657394459446	1.9260990569647525	0.0540920063665228	1.0	0.4025491187325755	5	Q8N4A0,Q10472	2
+MCM N-terminal domain [IPR027925]	0.7425671199158932	1.9074078796833345	0.0564677898008898	1.0	0.4025491187325755	6	Q14566	1
+MCM OB domain [IPR033762]	0.7425671199158932	1.9074078796833345	0.0564677898008898	1.0	0.4025491187325755	6	Q14566	1
+MCM, AAA-lid domain [IPR041562]	0.7425671199158932	1.9074078796833345	0.0564677898008898	1.0	0.4025491187325755	6	Q14566	1
+MCM domain [IPR001208]	0.7425671199158932	1.9074078796833345	0.0564677898008898	1.0	0.4025491187325755	6	Q14566	1
+GOLD domain [IPR009038]	0.716975985364709	1.8420376476304388	0.0654696431947374	1.0	0.4162907690785313	7	Q9Y3B3,Q9BVK6,Q7Z7H5,Q15363,P49755	5
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7017189079878534	1.7676894863538617	0.0771128285877105	1.0	0.4270864352550121	7	Q9NUQ2,Q86UL3,Q9HCL2,O15228,Q92604,Q8NF37	6
+Peptidase M16, N-terminal [IPR011765]	0.6994628996741423	1.756650659912853	0.0789773723421696	1.0	0.4305937806094236	7	Q5JRX3,P22695,Q10713	3
+Peptidase M16, C-terminal [IPR007863]	0.6994628996741423	1.756650659912853	0.0789773723421696	1.0	0.4305937806094236	7	Q5JRX3,P22695,Q10713	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8225589225589236	1.739945751676995	0.0818685439863879	1.0	0.4372656722744494	4	P08670,P07197,P07196	3
+Reticulon [IPR003388]	0.9737462133961612	1.7212322461553409	0.0852086885802954	1.0	0.4454996558251332	3	Q9NQC3,O95197	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.698942235926198	1.7001743038768236	0.0890981441367284	1.0	0.4532999823733394	6	O43169,O15173,O00264	3
+AMP-dependent synthetase/ligase [IPR000873]	0.7046299094099419	1.646198540146502	0.0997228897389868	1.0	0.4758706317369194	5	P33121,O95573	2
+FAD dependent oxidoreductase [IPR006076]	0.7851288996785557	1.5822478218694391	0.1135930071611199	1.0	0.5104200960073955	4	Q9H9P8,P43304	2
+ERAP1-like C-terminal domain [IPR024571]	0.9259508582968676	1.5330538387641075	0.125262590074207	1.0	0.5262888600750775	3	Q9NZ08,P55786	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.7685886551509116	1.5120642580507515	0.1305175163468632	1.0	0.5384243239742463	4	Q32P28	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.7685886551509113	1.5120642580507508	0.1305175163468634	1.0	0.5384243239742463	4	Q32P28	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9104678559407532	1.4718550984705003	0.141060011029676	1.0	0.5614281048750751	3	A6NIH7,Q13432	2
+N-acetylgalactosaminyltransferase [IPR045885]	0.8887707918333427	1.386003089738964	0.1657459600334729	1.0	0.6001056501224741	3	Q8N4A0	1
+Zinc finger, CHHC-type [IPR012996]	0.8731066980814524	1.3240149769063194	0.1854980707342806	1.0	0.6342168675384342	3	P55795,P52597	2
+Band 7 domain [IPR001107]	0.6000341280679218	1.3088750430716998	0.190576681707643	1.0	0.6419681199838223	8	O75477,P35232,O75955,Q99623,P27105	5
+AGC-kinase, C-terminal [IPR000961]	0.5873590775765137	1.2959519436797704	0.1949920418322732	1.0	0.6535677111912992	9	Q15418,P31751,P51812	3
+Tudor domain [IPR002999]	0.6296295765937928	1.289356891935572	0.1972740407415754	1.0	0.6537896910937031	5	Q14739,Q16637	2
+Complex 1 LYR protein domain [IPR008011]	0.9835127860026924	1.2441588138043842	0.2134411186188551	1.0	0.6771120555381555	2	Q9Y6M9	1
+Syntaxin, N-terminal domain [IPR006011]	0.6905723905723896	1.1786245493524918	0.2385477117326737	1.0	0.7112847726206887	4	Q12846,Q86Y82,O15400	3
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.6843818456625109	1.1521259895315237	0.249269304774794	1.0	0.7246647061142883	4	P25705	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.6843818456625109	1.1521259895315237	0.249269304774794	1.0	0.7246647061142883	4	P25705	1
+MENTAL domain [IPR019498]	0.9465006729475128	1.1070333774026055	0.2682794978195009	1.0	0.7529378923783794	2	O95772	1
+Thioredoxin domain [IPR013766]	0.400388819966244	1.0815585295072037	0.2794487401299921	1.0	0.7660588083294745	24	Q9H3N1,Q9H1E5,Q96JJ7,Q9Y320	4
+START domain [IPR002913]	0.9357335127860034	1.0674818697608175	0.2857542963388564	1.0	0.7729574778315143	2	Q14849	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.9286675639300154	1.0416310104854296	0.2975827856069273	1.0	0.7863576018368057	2	Q15418	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5166945513579093	1.020579444304568	0.3074537324375597	1.0	0.8000525243114086	11	Q96AY3,Q9NWM8,Q9Y680,O95302	4
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.789296533153818	0.9947742592902508	0.3198460681892805	1.0	0.8113815284221334	3	Q9ULX6,O43823	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.9145356662180402	0.990211814627736	0.3220705989743109	1.0	0.8128010646825549	2	Q32P28	1
+Glycosyl transferase, family 1 [IPR001296]	0.91318977119785	0.9853361127666516	0.3244589996944236	1.0	0.8136063240629295	2	Q9BT22	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9121803499327106	0.98168192314018	0.3262565737107787	1.0	0.8137160345442253	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9121803499327106	0.98168192314018	0.3262565737107787	1.0	0.8137160345442253	2	Q9Y282	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7788623359138203	0.9544186127155462	0.3398717884283404	1.0	0.8243624191853539	3	P16615,P05023	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7788623359138203	0.9544186127155462	0.3398717884283404	1.0	0.8243624191853539	3	P16615,P05023	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.9004037685060567	0.9392219329054162	0.3476168103712047	1.0	0.8294015124646288	2	Q9NVI7	1
+ELMO domain [IPR006816]	0.8977119784656797	0.9295637721061748	0.3525969921360146	1.0	0.8362742874005243	2	Q96JJ3	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8943472409152097	0.9175171609129308	0.3588717045466973	1.0	0.8414792162920501	2	O15254	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.7653988556041577	0.902693346166192	0.3666886688364428	1.0	0.8446600848771398	3	Q9UKG9,P23786	2
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8896366083445544	0.9007023584966944	0.3677465943627787	1.0	0.8446600848771398	2	Q8N2A8	1
+Lamin tail domain [IPR001322]	0.7643890945809471	0.8988314395129108	0.3687424510985215	1.0	0.8446600848771398	3	Q03252,P20700	2
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8876177658142732	0.8935146305737017	0.3715816407033134	1.0	0.8446600848771398	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8876177658142732	0.8935146305737017	0.3715816407033134	1.0	0.8446600848771398	2	Q13505	1
+SET domain [IPR001214]	0.7622544475766019	0.8906759135703541	0.3731030602058247	1.0	0.8446600848771398	3	Q03164	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.4984576379797122	0.8195662438924991	0.4124634236667397	1.0	0.8572078048535395	9	O60499,O15400,Q13190,Q9UNK0,Q12846,Q86Y82	6
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8647375504710645	0.8129110556150566	0.4162690554100592	1.0	0.8572078048535395	2	O60506	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5059262978458352	0.7830889193181009	0.4335748976248337	1.0	0.8732596186097183	7	O60313,Q8IWA4	2
+Dynamin, N-terminal [IPR045063]	0.5059262978458352	0.7830889193181009	0.4335748976248337	1.0	0.8732596186097183	7	O60313,Q8IWA4	2
+Immunoglobulin-like domain [IPR007110]	0.4763957597623519	0.7443408749361423	0.4566702786294305	1.0	0.8900707341439857	10	Q08722,P35613	2
+Major sperm protein (MSP) domain [IPR000535]	0.7206327835745507	0.7344378359534104	0.4626819341015884	1.0	0.8935393366252142	3	Q9P0L0,Q8NHP6	2
+Aldehyde dehydrogenase domain [IPR015590]	0.4822632811919883	0.7338724495707297	0.4630264795870344	1.0	0.8935393366252142	9	P51649,P51648	2
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4807336540962892	0.7258249219138079	0.4679461067865116	1.0	0.8973014059236554	9	Q03518,P28288,P08183,P33527	4
+Acyltransferase, C-terminal domain [IPR032098]	0.8344549125168286	0.709088248471672	0.478269715020934	1.0	0.8978560294258027	2	Q9NUQ2	1
+Fatty acid desaturase domain [IPR005804]	0.8331090174966396	0.7045616344573461	0.4810830811383999	1.0	0.9003756747911338	2	O15121	1
+Immunoglobulin C1-set [IPR003597]	0.5764865866621245	0.6989415408822428	0.4845885653092574	1.0	0.9034827173473436	4	P10321,P04439	2
+MHC class I-like antigen recognition-like [IPR011161]	0.5764865866621245	0.6989415408822428	0.4845885653092574	1.0	0.9034827173473436	4	P10321,P04439	2
+FAD-binding domain, PCMH-type [IPR016166]	0.8297442799461725	0.6932808561503899	0.4881333145487558	1.0	0.9041648139087408	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8297442799461725	0.6932808561503899	0.4881333145487558	1.0	0.9041648139087408	2	Q15392	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.7075153705090145	0.686538850044824	0.4923733743558665	1.0	0.9061500839536564	3	P33121	1
+Tim44-like domain [IPR007379]	0.8277254374158871	0.6865373305862752	0.4923743321670892	1.0	0.9061500839536564	2	O43615	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.4919090504849737	0.6847627827149853	0.4934936240610412	1.0	0.90628086399207	6	Q9H7Z7,P78417	2
+CBS domain [IPR000644]	0.4809097611573684	0.6588877273986217	0.5099678672864192	1.0	0.9132416526094764	7	P51790,Q8NE01	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.6960619320094116	0.6453641221075958	0.5186912479664152	1.0	0.916789581373446	3	P10321,P04439	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.6960619320094116	0.6453641221075958	0.5186912479664152	1.0	0.916789581373446	3	P10321,P04439	2
+CARG-binding factor, N-terminal [IPR012956]	0.8075370121130567	0.6201987401298512	0.5351269508735126	1.0	0.9253799790159551	2	Q99729	1
+Guanylate kinase-like domain [IPR008144]	0.4875211796505166	0.6156902178010223	0.538098994752366	1.0	0.9253799790159551	5	Q00013,Q9NZW5,Q92796	3
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4875211796505166	0.6156902178010223	0.538098994752366	1.0	0.9253799790159551	5	Q00013,Q9NZW5,Q92796	3
+Peptidase M41 [IPR000642]	0.8058546433378176	0.6147658476453008	0.5387093666575131	1.0	0.9253799790159551	2	Q9Y4W6	1
+Sterile alpha motif domain [IPR001660]	0.4656102494942473	0.6130971858470674	0.5398120808718869	1.0	0.9253799790159551	8	Q9Y3Z3,Q6SZW1,Q9UQR0,Q9Y6Y8,Q8IXK0,Q15375,Q13586	7
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8034993270524932	0.6071858579902839	0.5437275763519789	1.0	0.9253799790159551	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8034993270524932	0.6071858579902839	0.5437275763519789	1.0	0.9253799790159551	2	P40939	1
+DZF domain [IPR006561]	0.5468013468013407	0.5809023064773644	0.5613062977772889	1.0	0.9352598588687632	4	Q12905,Q96KR1,Q96SI9	3
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.6727826919902362	0.5638222697110123	0.5728750943221401	1.0	0.9395977270300748	3	Q1KMD3	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.6701447324133133	0.554783347342951	0.5790428588087795	1.0	0.9422970749578896	3	P00387,P16435	2
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.6701447324133133	0.554783347342951	0.5790428588087795	1.0	0.9422970749578896	3	P00387,P16435	2
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.6701447324133133	0.554783347342951	0.5790428588087795	1.0	0.9422970749578896	3	P00387,P16435	2
+NOPS [IPR012975]	0.6691349713900951	0.5513350558497699	0.581404011556558	1.0	0.9423900910139834	3	P23246,Q15233	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.7836473755047144	0.5445723677201739	0.5860476636331502	1.0	0.9432246420604548	2	Q8IWA4	1
+SCP2 sterol-binding domain [IPR003033]	0.6659579528463895	0.540528440880533	0.5888326525835863	1.0	0.9439831915681856	3	Q6YN16	1
+Armadillo repeat-containing domain [IPR006911]	0.7806191117092898	0.5352328169019314	0.5924888763119158	1.0	0.9443918364772916	2	Q8N2F6	1
+Marvel domain [IPR008253]	0.7752355316285439	0.5187758789546428	0.6039170405237333	1.0	0.9495111851008986	2	O43760	1
+CNNM, transmembrane domain [IPR002550]	0.7715343203230214	0.5075733575156821	0.6117525788586453	1.0	0.9532370512992816	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.7715343203230214	0.5075733575156821	0.6117525788586453	1.0	0.9532370512992816	2	Q8NE01	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7617765814266508	0.4784918444770337	0.632300177574133	1.0	0.9623997728457896	2	Q8NF37	1
+Myb domain [IPR017930]	0.4430592991913561	0.4566300908216681	0.6479369470621048	1.0	0.9712869997995958	6	Q13330,Q8TAQ2,Q96KC8,Q92922,Q99543	5
+Diacylglycerol kinase, catalytic domain [IPR001206]	0.6391582812757729	0.4521616518420217	0.6511525320897993	1.0	0.9712869997995958	3	Q53H12	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.7500000000000084	0.4443097120217184	0.6568186804959355	1.0	0.9712869997995958	2	Q9HCL2	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.7500000000000084	0.4443097120217184	0.6568186804959355	1.0	0.9712869997995958	2	Q9HCL2	1
+Fibronectin type II domain [IPR000562]	0.6360770859872549	0.4423480149700771	0.6582373907955594	1.0	0.9712869997995958	3	Q9UBV2	1
+Pleckstrin homology domain 8 [IPR041680]	0.7462987886944857	0.4337833486270812	0.664445774455436	1.0	0.9754998209428654	2	Q9H4L5	1
+SUN coiled coil domain 2 [IPR040994]	0.7452893674293435	0.4309310196775921	0.6665185277971442	1.0	0.9754998209428654	2	Q9UH99	1
+Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]	0.7365410497981215	0.4065504581037286	0.684338190215865	1.0	0.9754998209428654	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.7365410497981215	0.4065504581037286	0.684338190215865	1.0	0.9754998209428654	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]	0.7365410497981215	0.4065504581037286	0.684338190215865	1.0	0.9754998209428654	2	Q96RL7	1
+VPS13, repeated coiled region [IPR031642]	0.7365410497981215	0.4065504581037286	0.684338190215865	1.0	0.9754998209428654	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]	0.7365410497981215	0.4065504581037286	0.684338190215865	1.0	0.9754998209428654	2	Q96RL7	1
+Rhodanese-like domain [IPR001763]	0.4937359933133642	0.3846429715639705	0.7005019523078453	1.0	0.979013590391858	4	Q8NCN5,Q99956	2
+Glycosyltransferase 2-like [IPR001173]	0.4929300872463021	0.3818504867160566	0.7025722681334969	1.0	0.979013590391858	4	Q8N4A0	1
+FCP1 homology domain [IPR004274]	0.6104621955785217	0.3638817989644276	0.7159462766202136	1.0	0.979013590391858	3	Q3ZCQ8	1
+Bromodomain [IPR001487]	0.3967030331823893	0.3618043641834612	0.7174982306393896	1.0	0.979013590391858	11	Q03164	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.7190444145356653	0.3596971408051579	0.719073630437502	1.0	0.979013590391858	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.7190444145356653	0.3596971408051579	0.719073630437502	1.0	0.979013590391858	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.7190444145356653	0.3596971408051579	0.719073630437502	1.0	0.979013590391858	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.7190444145356653	0.3596971408051579	0.719073630437502	1.0	0.979013590391858	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.7190444145356653	0.3596971408051579	0.719073630437502	1.0	0.979013590391858	2	A0FGR8	1
+NIPSNAP [IPR012577]	0.7113055181695884	0.3398266886608082	0.7339870480923045	1.0	0.979013590391858	2	Q9BPW8	1
+EF hand associated, type-2 [IPR013567]	0.6914535666218105	0.2913934647387405	0.770750412181735	1.0	0.979013590391858	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.6914535666218105	0.2913934647387405	0.770750412181735	1.0	0.979013590391858	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.6914535666218105	0.2913934647387405	0.770750412181735	1.0	0.979013590391858	2	Q8IXI1	1
+Glycosyl hydrolase, family 13, catalytic domain [IPR006047]	0.6867429340511447	0.2804575207410211	0.7791265117131705	1.0	0.979013590391858	2	P08195	1
+L27 domain, C-terminal [IPR014775]	0.6806864064603018	0.2667207662758694	0.789684163785644	1.0	0.979013590391858	2	Q9NZW5	1
+L27 domain [IPR004172]	0.6806864064603018	0.2667207662758694	0.789684163785644	1.0	0.979013590391858	2	Q9NZW5	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6796769851951592	0.2644671020528499	0.7914200113726271	1.0	0.979013590391858	2	Q92945	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.669919246298791	0.2432164800597453	0.8078377008708548	1.0	0.979013590391858	2	P00387	1
+SAM domain [IPR041418]	0.6588156123822431	0.220233110892121	0.8256896108452043	1.0	0.979013590391858	2	Q9NZI7	1
+CP2 transcription factor [IPR007604]	0.6588156123822431	0.220233110892121	0.8256896108452043	1.0	0.979013590391858	2	Q9NZI7	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.65847913862719	0.2195568382770333	0.8262163091989077	1.0	0.979013590391858	2	P05067	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.5513695218754847	0.2077940013652023	0.8353898166058855	1.0	0.979013590391858	3	Q9BSJ2	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.5513695218754847	0.2077940013652023	0.8353898166058855	1.0	0.979013590391858	3	Q9BSJ2	1
+Chromo domain subgroup [IPR017984]	0.5449343655334766	0.1931876444556257	0.8468120147649763	1.0	0.979013590391858	3	P83916,P45973	2
+Chromo shadow domain [IPR008251]	0.5449343655334766	0.1931876444556257	0.8468120147649763	1.0	0.979013590391858	3	P83916,P45973	2
+Brix domain [IPR007109]	0.3812731559447609	0.1881725338057688	0.8507414027086984	1.0	0.979013590391858	5	Q96G21,Q9H7B2,Q9H9Y2,Q9NQ55	4
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6362718707940855	0.1775926628543982	0.8590428871404177	1.0	0.979013590391858	2	P34897	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3698583951449679	0.1775694547551385	0.8590611148411433	1.0	0.979013590391858	8	Q6P2Q9,Q92905,O15372,O95630,P51665,O00303,Q7L5N1	7
+SUN domain [IPR012919]	0.5341071219051207	0.1697577163315452	0.865200681662879	1.0	0.979013590391858	3	Q9UH99	1
+EF-hand, Ca insensitive [IPR014837]	0.5001682935038647	0.1058822389051771	0.9156757861436292	1.0	0.9874427331732298	3	P12814,Q13813	2
+SGS domain [IPR007699]	0.5679676985195243	0.0816591107253328	0.9349177946339506	1.0	0.9920584140719164	2	Q9Y2Z0	1
+Dehydrogenase, E1 component [IPR001017]	0.5629205921938182	0.0764838038435488	0.9390341988899162	1.0	0.9955633256312322	2	Q02218	1
+RasGAP protein, C-terminal [IPR000593]	0.5592193808882964	0.0728449494799578	0.9419295014330724	1.0	0.9978883808429754	2	Q13576	1
+FYVE zinc finger [IPR000306]	0.3737373737373708	0.0606346205451729	0.9516502010308516	1.0	1.0	4	Q96T51,Q9P2R3,O14964	3
+Zinc finger, FYVE-related [IPR017455]	0.3737373737373708	0.0606346205451729	0.9516502010308516	1.0	1.0	4	Q96T51,Q9P2R3,O14964	3
+Zinc finger, ZZ-type [IPR000433]	0.542059219380899	0.0576426036762921	0.9540333132439748	1.0	1.0	2	P46939	1
+GTPase effector domain [IPR020850]	0.5393674293405218	0.0554981823596558	0.9557415779871392	1.0	1.0	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.5393674293405218	0.0554981823596558	0.9557415779871392	1.0	1.0	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.5393674293405218	0.0554981823596558	0.9557415779871392	1.0	1.0	2	P50570	1
+Glycoside hydrolase family 31, N-terminal domain [IPR025887]	0.5390309555854734	0.0552345580775643	0.9559515975835424	1.0	1.0	2	Q14697	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.5326379542395733	0.0504094915291674	0.9597960728576314	1.0	1.0	2	Q9NRG7	1
+Fumarylacetoacetase-like, C-terminal [IPR011234]	0.5201884253028385	0.0419788287778801	0.9665155754248916	1.0	1.0	2	P16930	1
+PABP, RNA recognition motif 2 [IPR045305]	0.5158142664872236	0.0393051951787292	0.9686470646650988	1.0	1.0	2	Q13310	1
+PB1 domain [IPR000270]	0.5100942126514233	0.0360239059000917	0.9712632971711554	1.0	1.0	2	Q13501	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.504374158815625	0.0329770233300003	0.9736929104002872	1.0	1.0	2	Q969Z0	1
+RAP domain [IPR013584]	0.504374158815625	0.0329770233300003	0.9736929104002872	1.0	1.0	2	Q969Z0	1
+FAST kinase leucine-rich [IPR010622]	0.504374158815625	0.0329770233300003	0.9736929104002872	1.0	1.0	2	Q969Z0	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.5026917900403793	0.0321240117741615	0.9743731546630828	1.0	1.0	2	P31949	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.4409289801413583	0.0289485434832615	0.9769056297256686	1.0	1.0	3	Q5T8D3,Q9H3P7	2
+Sec23, C-terminal [IPR037550]	0.4838492597577377	0.0238165393719365	0.9809989472804472	1.0	1.0	2	Q15437	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.4754374158815682	0.0207854733543376	0.9834167858208428	1.0	1.0	2	Q8WUM0	1
+MoaB/Mog domain [IPR001453]	0.4747644683714823	0.0205594892162802	0.983597056551604	1.0	1.0	2	Q8NFF5	1
+Sorting nexin, N-terminal [IPR005329]	0.470390309555853	0.0191474782653595	0.9847234561822964	1.0	1.0	2	O60749	1
+Acyl transferase [IPR014043]	0.4579407806191163	0.0156355714032519	0.9875251272710476	1.0	1.0	2	Q8IVS2	1
+SMARCC, N-terminal [IPR032450]	0.4468371467025742	0.0130724556158916	0.98956998655574	1.0	1.0	2	Q8TAQ2	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.4468371467025742	0.0130724556158916	0.98956998655574	1.0	1.0	2	Q8TAQ2	1
+SMARCC, C-terminal [IPR032451]	0.4468371467025742	0.0130724556158916	0.98956998655574	1.0	1.0	2	Q8TAQ2	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4197239986536469	0.0111700201068774	0.9910877987415088	1.0	1.0	3	P14866,P26599	2
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.4205921938088827	0.00874694775059	0.9930210344281584	1.0	1.0	2	P54725	1
+XPC-binding domain [IPR015360]	0.4205921938088827	0.00874694775059	0.9930210344281584	1.0	1.0	2	P54725	1
+Hyaluronan-mediated motility receptor, C-terminal [IPR031794]	0.3617092866756379	0.0046415506580506	0.996296591689462	1.0	1.0	2	O75330	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.3395020188425309	0.004138233386793	0.9966981768956216	1.0	1.0	2	Q9Y305	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.3213324360699821	0.0039180670805878	0.9968738427666144	1.0	1.0	2	P10644	1
+Man1/Src1, C-terminal [IPR018996]	0.3001345895020114	0.0037860927858501	0.996979142237485	1.0	1.0	2	Q9Y2U8	1
+Hemimethylated DNA-binding domain [IPR011722]	0.2748990578734789	0.0037205296059273	0.9970314537180268	1.0	1.0	2	Q9Y2S7	1
+Ras GTPase-activating domain [IPR001936]	0.406597105351708	0.0023734393858258	0.9981062711360118	1.0	1.0	3	Q13576,P46940	2
+Peptidase M28 [IPR007484]	0.403904409289784	0.0007603519227724	0.9993933269984996	1.0	1.0	3	Q969V3,Q7Z2K6	2