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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:69d274e9787c798d4411001a2f0908a3244074e0b8512a3221c6c1182eb3d777
+size 67988

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.547169811320755
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C219/C219_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.8815185601812983	1.6411962161634217	0.1007566909314303	0.9964067089203524	0.3814360442404149	3	P10619	1
+Histidine acid phosphatase active site [IPR033379]	0.8277254374158889	1.0121079669312425	0.3114864335376843	0.999999997433374	0.64001089499178	2	P11117	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.4484735723945763	0.1322813603110349	0.8947617501248506	1.0	0.9733741229286232	3	P00390	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K2", "MAPK1", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1"], "leading_proteins": ["ACP2", "CTSA", "GSR"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:5ac8132114c36132972055ff04c76d8b60cb5b0ce94f85299c5bd2ae1835157c
+size 67283

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M16, zinc-binding site [IPR001431]	1	5	1.9662971281234565	0.0492642983757847	1.730582524271845	5.0	0.6776547957610433	0.4740055886775391	1.2118895823030245	0.0	0.8079860258854747	0.314626832259423	0.1060422385006095	1.0	1.0	0.1136393161191851	0.0210033734704291

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.32258064516129
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C219/C219_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.809082177349064	1.9662971281234565	0.0492642983757847	0.7911406690775719	0.1933907213699811	5	P22695	1
+EF-Hand 1, calcium-binding site [IPR018247]	0.5464905079699853	1.8577313579846817	0.063207173089218	0.8678855697303324	0.1933907213699811	36	Q9BPX6,Q96AY3,O43852,Q9Y680,Q6NUK1,Q15293,O75746,O95202,P80303,Q02818,P41208,O95302,Q14257	13
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.7304845222072686	0.6434293326590638	0.5199455552983239	0.9999999998681728	0.7377460791926201	2	O75600	1
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.6965006729475106	0.5266043224068313	0.59846838972473	0.9999999999994807	0.8066313078898535	2	P34897	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K2", "MAPK1", "MAPK14", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP7", "FKBP9", "GCAT", "LETM1", "MICU1", "NUCB1", "NUCB2", "RCN1", "RCN2", "SHMT2", "SLC25A12", "SLC25A24", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:2856449334177bb662ee5edc75c8a88684ed01ca33639a74f6b0fc03afa4a6bf
+size 75190

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	6	7	2.157086311672913	0.0309989399551042	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0324869352130368	1.0	0.0061398538588971	0.0371151708183716	0.0026822887756782

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 270,
+    "title": "Average number of proteins per term",
+    "value": 2.6259259259259258
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C219/C219_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,28 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7917087967643944	2.157086311672913	0.0309989399551042	0.999796975672517	0.53787168463378	7	Q13190,Q12846,Q86Y82,Q13277,O60499,Q9P2W9	6
+Tetraspanin, conserved site [IPR018503]	0.980814540558733	2.0349991804894563	0.0418509554396822	0.9999902964838132	0.53787168463378	3	O43657,O60637	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.682882977944012	1.770730656907431	0.0766055019255185	0.9999999995485952	0.5380887971772635	8	P49721,P28074	2
+Haem oxygenase conserved site [IPR018207]	0.954239569313596	1.5254926676865397	0.1271362610166257	1.0	0.6356813050831289	2	P30519	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8358776995837156	1.4574205019851931	0.1450003411429228	1.0	0.6465388098311698	3	Q8N4Q0	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.8349200870822289	1.4535544283633528	0.1460698792581531	1.0	0.6465388098311698	3	P78527	1
+Sterol reductase, conserved site [IPR018083]	0.9064602960969084	1.3299255206297629	0.1835428119364948	1.0	0.6882855447618556	2	Q9UBM7	1
+ABC transporter-like, conserved site [IPR017871]	0.5761797565061867	1.3053223550346118	0.1917831050006295	1.0	0.6966867515863817	9	P33527,Q03518,P08183	3
+Thioredoxin, conserved site [IPR017937]	0.5283759547082529	1.299727818000095	0.1936942725683825	1.0	0.6966867515863817	12	Q9H1E5,O43396	2
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.8670928667563944	1.1698806156884023	0.2420490156779937	1.0	0.709394430010203	2	P13473	1
+AMP-binding, conserved site [IPR020845]	0.6272912925618502	1.1490510409686518	0.250534934725316	1.0	0.709394430010203	5	P33121,O95573	2
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.5798905302049159	1.144951784894826	0.2522291306702944	1.0	0.709394430010203	7	P51648	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8263795423956999	1.0067721576903357	0.3140442772627803	1.0	0.782160480845064	2	Q9BTY2	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.7822550879680652	2	P05067	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.7822550879680652	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.7822550879680652	2	P05067	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.5730392622609715	0.902083591992588	0.3670124643066819	1.0	0.8122406996951157	5	Q9H4L5	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5221619643954643	0.8604377333904147	0.3895477933038145	1.0	0.8292137815454341	7	P51648	1
+Glycoside hydrolase family 27/36, conserved site [IPR000111]	0.7691790040376946	0.7852342324291097	0.4323162480260998	1.0	0.8327073520559155	2	P06280	1
+Polyprenyl synthetase, conserved site [IPR033749]	0.7631224764468356	0.7625242135457384	0.4457471972767242	1.0	0.8327073520559155	2	P14324	1
+Intermediate filament protein, conserved site [IPR018039]	0.4760959146120272	0.7244599633676639	0.4687833981944413	1.0	0.8327073520559155	8	P07197,Q03252,P20700,Q16352,P07196	5
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.6978465679677016	0.53106797343817	0.5953716766152657	1.0	0.9625769621923458	2	Q16836	1
+Ribosomal protein L3, conserved site [IPR019926]	0.6231493943472464	0.308753448348764	0.757509082872101	1.0	1.0	2	P09001	1
+Histidine triad, conserved site [IPR019808]	0.5417227456258492	0.1395100992628494	0.8890470759249913	1.0	1.0	2	Q96C86	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.5198519515477915	0.1085066492480931	0.9135938063210274	1.0	1.0	2	P50570	1
+S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]	0.5195154777927402	0.1080762343613641	0.9139352199457392	1.0	1.0	2	O43865	1
+Ribosomal protein S9, conserved site [IPR020574]	0.5016823687752489	0.0872074416147813	0.930506624341644	1.0	1.0	2	P82933	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Ferritin, conserved site [IPR014034]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FTL", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MKRN2", "MPI", "MPP1", "MPP6", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "NAGA", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCC1", "ACSL1", "ACSL3", "AHCYL1", "ALDH3A2", "APP", "DCPS", "DHCR7", "DNM2", "FDPS", "FUCA2", "GLA", "HADH", "HMOX2", "INA", "LAMP2", "LMNB1", "LMNB2", "MRPL3", "MRPS9", "NEFL", "NEFM", "OSBPL3", "PRKDC", "PSMB2", "PSMB5", "STX10", "STX12", "STX18", "STX3", "STX4", "STX5", "TAP1", "TMX4", "TSPAN3", "TSPAN6", "TXNL1", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Phospholipid/glycerol acyltransferase [IPR002123]", "2": "Band 7 domain [IPR001107]", "3": "Target SNARE coiled-coil homology domain [IPR000727]", "4": "Intermediate filament, rod domain [IPR039008]", "5": "Thioredoxin domain [IPR013766]", "6": "Rab-GTPase-TBC domain [IPR000195]", "7": "Importin-beta, N-terminal domain [IPR001494]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:0bded470113bddbd94d44066ae2c483969b65945cd360d8033cd275bd35fde88
+size 131905

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M16, C-terminal [IPR007863]	3	7	2.356393778873977	0.0184533443984205	2.6067961165048543	7.0	0.7914914082442276	0.4366893661235884	1.5075062759483802	0.0	0.8715475629418188	0.3304871916560691	0.0095447235363193	1.0	1.0	0.1554071649538126	0.0001655432264732
+Peptidase M16, N-terminal [IPR011765]	3	7	2.356393778873977	0.0184533443984205	2.6067961165048543	7.0	0.7914914082442276	0.4366893661235884	1.5075062759483802	0.0	0.8715475629418188	0.3304871916560691	0.0095447235363193	1.0	1.0	0.1554071649538126	0.0001655432264732
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	3	5	2.2495992247346304	0.0244743977182404	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0005542616025668	1.0	0.0714416582380786	0.000685273375659	0.0003184906810585
+Aminopeptidase N-like , N-terminal domain [IPR045357]	3	5	2.2495992247346304	0.0244743977182404	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0005542616025668	1.0	0.0714416582380786	0.000685273375659	0.0003184906810585
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	2.201083051631313	0.027730144883822	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0121253085468692	1.0	1.0	0.0147337868082452	0.0033786658518103
+EF-hand domain [IPR002048]	17	42	2.136145217416636	0.0326675790987973	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	7.104324449043474e-05	0.3714211816184957	0.0135552020852883	0.0001297291955945	1.1064853280419176e-06

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2974,
+    "annotations_size": 2448,
+    "title": "Average number of proteins per term",
+    "value": 2.110294117647059
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C219/C219_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,193 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, C-terminal [IPR007863]	0.8359864504388674	2.356393778873977	0.0184533443984205	1.0	0.6779778731022903	7	P22695,Q10713,Q5JRX3	3
+Peptidase M16, N-terminal [IPR011765]	0.8359864504388674	2.356393778873977	0.0184533443984205	1.0	0.6779778731022903	7	P22695,Q10713,Q5JRX3	3
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8750239892934781	2.2495992247346304	0.0244743977182404	1.0	0.6779778731022903	5	P55786,Q9NZ08,Q9UIQ6	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8750239892934781	2.2495992247346304	0.0244743977182404	1.0	0.6779778731022903	5	P55786,Q9NZ08,Q9UIQ6	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8635904344897268	2.201083051631313	0.027730144883822	1.0	0.6779778731022903	5	Q9HD20,P16615,P05023,P35670	4
+EF-hand domain [IPR002048]	0.5739873535233393	2.136145217416636	0.0326675790987973	1.0	0.6779778731022903	42	O75071,Q8NF37,Q9BPX6,Q96AY3,O43852,Q9Y680,Q6NUK1,Q15293,Q8IYU8,O75746,O95202,P80303,Q02818,P41208,Q14257,O95302,Q9UJS0	17
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8956228956229024	2.0871358630392134	0.0368758550651615	1.0	0.6779778731022903	4	Q96CP7,Q15629,Q96G23	3
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9777852574890588	2.0231457674437183	0.0430581211096749	1.0	0.6779778731022903	3	O43924,Q13432	2
+GOLD domain [IPR009038]	0.7305443889425881	1.8741559528400653	0.0609089331699983	1.0	0.6779778731022903	7	Q7Z7H5,Q9Y3B3,Q9BVK6,Q15363	4
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7234623856447109	1.8408384505123552	0.0656452362777646	1.0	0.6779778731022903	7	Q92604,Q99943,Q9NUQ2,O15228,Q8NF37	5
+Reticulon [IPR003388]	0.9299899023897624	1.8347022532443784	0.0665498182572474	1.0	0.6779778731022903	3	O95197,Q9NQC3	2
+ERAP1-like C-terminal domain [IPR024571]	0.924604510265899	1.813311769069712	0.0697837491092032	1.0	0.6779778731022903	3	P55786,Q9UIQ6	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7699354063375482	1.7942473013655718	0.0727737053198591	1.0	0.6779778731022903	5	P33527,Q03518,P08183	3
+Band 7 domain [IPR001107]	0.6863162028455345	1.7875359029546611	0.073850914668831	1.0	0.6779778731022903	8	P27105,Q99623,Q9UJZ1,O75955,Q14254	5
+LEM domain [IPR003887]	0.7185100733984511	1.6958876483700276	0.0899071592490117	1.0	0.6779778731022903	6	Q86XL3,P42167	2
+Dynamin, N-terminal [IPR045063]	0.6887796020383015	1.6760823740531017	0.0937220587195897	1.0	0.6779778731022903	7	O95140,Q9H4M9,Q8IWA4,O60313	4
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6887796020383015	1.6760823740531017	0.0937220587195897	1.0	0.6779778731022903	7	O95140,Q9H4M9,Q8IWA4,O60313	4
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6094914216175654	1.6644214469969945	0.0960282370457965	1.0	0.6779778731022903	11	O95302,Q9Y680,Q96AY3,Q9NWM8	4
+Syntaxin, N-terminal domain [IPR006011]	0.7909090909090915	1.6509615513804852	0.0987464260674619	1.0	0.6779778731022903	4	Q86Y82,Q13277,Q12846	3
+MENTAL domain [IPR019498]	0.9771197846567978	1.6192176930653874	0.1054004324585071	1.0	0.6898937397284105	2	O95772	1
+Ricin B, lectin domain [IPR000772]	0.7267784065981169	1.6015587072252575	0.1092532281513305	1.0	0.6955479852712024	5	Q8N4A0,Q10472	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8630090878492023	1.5668047915031489	0.1171603270859922	1.0	0.6955479852712024	3	P16615,P05023	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8630090878492023	1.5668047915031489	0.1171603270859922	1.0	0.6955479852712024	3	P16615,P05023	2
+FAD linked oxidase, N-terminal [IPR006094]	0.9586137281292066	1.5434157448633872	0.1227299359138367	1.0	0.6955479852712024	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9586137281292066	1.5434157448633872	0.1227299359138367	1.0	0.6955479852712024	2	Q15392	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.629921619146517	1.5079968638523913	0.1315553296750697	1.0	0.7163834355981007	8	P11310,O15254	2
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8483839185444095	1.5078817420436643	0.131584796320241	1.0	0.7163834355981007	3	P52888	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.8458981742169728	1.497856809896409	0.1341704570899837	1.0	0.7187073937774184	3	Q8N4A0	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9427994616419956	1.4786175276136746	0.1392425654904621	1.0	0.7232881460825312	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9427994616419956	1.4786175276136746	0.1392425654904621	1.0	0.7232881460825312	2	Q9Y282	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9253028263795464	1.406963626758186	0.1594381747119522	1.0	0.747695313824873	2	Q8N2A8	1
+Peptidase M28 [IPR007484]	0.8209357118815076	1.397072082757652	0.1623918959213708	1.0	0.747695313824873	3	Q969V3,Q7Z2K6	2
+CBS domain [IPR000644]	0.6240158576191688	1.3621503697613524	0.173150434876887	1.0	0.747695313824873	7	P51798,P51790,Q8NE01	3
+FAD dependent oxidoreductase [IPR006076]	0.7164983164983267	1.3332011625926108	0.1824657979380912	1.0	0.747695313824873	4	Q96CU9,Q9H9P8,Q8NCN5	3
+SET domain [IPR001214]	0.8047795355099163	1.331793054959539	0.182928200758444	1.0	0.747695313824873	3	Q9H7B4,Q03164	2
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5761797565061867	1.3053223550346118	0.1917831050006295	1.0	0.7506552209347974	9	P33527,Q03518,P08183	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.6277035498601766	1.2692250051975074	0.2043608251204096	1.0	0.7547671070090868	6	O15173,Q8WUJ1,O43169	3
+Target SNARE coiled-coil homology domain [IPR000727]	0.5689261223054896	1.2669758710251184	0.2051639177195778	1.0	0.7547671070090868	9	Q13190,Q12846,Q86Y82,Q13277,O60499	5
+Complex 1 LYR protein domain [IPR008011]	0.884589502018845	1.2408115614367132	0.2146753692395164	1.0	0.7629515664260762	2	Q9Y6M9	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8795423956931367	1.2203121683452818	0.2223465586810711	1.0	0.7714531386679321	2	O15254	1
+START domain [IPR002913]	0.8771870794078127	1.2107558569271577	0.2259889878534728	1.0	0.7714531386679321	2	Q14849	1
+Tudor domain [IPR002999]	0.6384726010815318	1.2001844745503996	0.230067703602846	1.0	0.775040473412722	5	Q9Y2W6,Q14739	2
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.6377521110168483	1.1968895130686747	0.2313496222003721	1.0	0.7754394415518205	5	P78527	1
+Major facilitator superfamily domain [IPR020846]	0.7624856810663424	1.1612287400786423	0.2455488899407212	1.0	0.7796416116405779	3	Q7L0J3	1
+AMP-dependent synthetase/ligase [IPR000873]	0.6272912925618502	1.1490510409686518	0.250534934725316	1.0	0.7864186451629988	5	P33121,O95573	2
+Glycosyltransferase 2-like [IPR001173]	0.6710499585454335	1.1380365452982422	0.2551052225890267	1.0	0.7864186451629988	4	Q8N4A0	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8586810228802156	1.135929520271329	0.2559860624015528	1.0	0.7868513729343796	2	Q9NVI7	1
+Glycosyl transferase, family 1 [IPR001296]	0.8499327052489937	1.1007439855148051	0.2710080968010724	1.0	0.801410248304377	2	Q9BT22	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8485868102288115	1.095343043611342	0.2733663766656873	1.0	0.801410248304377	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8485868102288115	1.095343043611342	0.2733663766656873	1.0	0.801410248304377	2	Q13505	1
+SUN domain [IPR012919]	0.7445304611241932	1.0892103164602278	0.2760611505907555	1.0	0.8020988702222082	3	Q9ULT8,O94901	2
+Fatty acid desaturase domain [IPR005804]	0.8347913862718799	1.0401928588736684	0.2982503085703234	1.0	0.8148624502010623	2	O15121	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.7310777831915096	1.0355172957057484	0.3004273934180557	1.0	0.8153506198308207	3	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.7310777831915096	1.0355172957057484	0.3004273934180557	1.0	0.8153506198308207	3	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.7310777831915096	1.0355172957057484	0.3004273934180557	1.0	0.8153506198308207	3	P16435	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.6417508417508418	1.0127966010335656	0.3111573245689127	1.0	0.8315645529963956	4	P07196,P07197,Q16352	3
+Acyltransferase, C-terminal domain [IPR032098]	0.8273889636608429	1.0107735914575335	0.3121248054674956	1.0	0.8324606219285203	2	Q9NUQ2	1
+Ion transporter-like, CBS domain [IPR044751]	0.8267160161507443	1.008105685700303	0.313403728400436	1.0	0.8324606219285203	2	Q8NE01	1
+CNNM, transmembrane domain [IPR002550]	0.8267160161507443	1.008105685700303	0.313403728400436	1.0	0.8324606219285203	2	Q8NE01	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8263795423956999	1.0067721576903357	0.3140442772627803	1.0	0.8324606219285203	2	Q9BTY2	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7223157186132496	1.0007010985648883	0.3169713361455895	1.0	0.8324606219285203	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7223157186132496	1.0007010985648883	0.3169713361455895	1.0	0.8324606219285203	3	P10321,P01889	2
+Zinc finger, CHHC-type [IPR012996]	0.7209693705822927	0.9953636909624848	0.3195594112062614	1.0	0.8327998361130154	3	P55795,P52597	2
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.8179676985195159	0.9735295145617024	0.3302901986836264	1.0	0.8365580950480455	2	P05067	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.4666384513706116	0.9710048428050204	0.3315458670031757	1.0	0.8365580950480455	13	Q14498	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.8172947510094195	0.9708783373382625	0.3316088667296286	1.0	0.8365580950480455	2	Q8IWA4	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]	0.8088829071332533	0.937848606897946	0.348322217575534	1.0	0.8492956062001069	2	Q13423	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]	0.8088829071332533	0.937848606897946	0.348322217575534	1.0	0.8492956062001069	2	Q13423	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8051816958277282	0.9233831755030936	0.3558075563124405	1.0	0.8497460660268026	2	Q32P28	1
+Post-SET domain [IPR003616]	0.8045087483176363	0.920757748165596	0.3571769188275029	1.0	0.8497460660268026	2	Q03164	1
+Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]	0.7971063257065989	0.8919765372394419	0.3724055085380033	1.0	0.8544394237306485	2	Q96RL7	1
+VPS13, repeated coiled region [IPR031642]	0.7971063257065989	0.8919765372394419	0.3724055085380033	1.0	0.8544394237306485	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.7971063257065989	0.8919765372394419	0.3724055085380033	1.0	0.8544394237306485	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]	0.7971063257065989	0.8919765372394419	0.3724055085380033	1.0	0.8544394237306485	2	Q96RL7	1
+Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]	0.7971063257065989	0.8919765372394419	0.3724055085380033	1.0	0.8544394237306485	2	Q96RL7	1
+Extended PHD (ePHD) domain [IPR034732]	0.796096904441459	0.8880662673743249	0.3745051064532629	1.0	0.8544394237306485	2	Q03164	1
+Immunoglobulin-like domain [IPR007110]	0.4836853298074379	0.8750384852766881	0.3815529658338255	1.0	0.8632763404985396	10	P35613,P10586,P10321,Q08722	4
+Pleckstrin homology domain 8 [IPR041680]	0.7886944818304173	0.8595027451769138	0.3900632061151432	1.0	0.8716185131170555	2	Q9H4L5	1
+Marvel domain [IPR008253]	0.7833109017496742	0.8388587071427025	0.4015486019935161	1.0	0.8776705157858282	2	O43760	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.6794398605980092	0.8328100158714555	0.4049518850746558	1.0	0.8800553823322832	3	Q9NUQ9	1
+Tim44-like domain [IPR007379]	0.777590847913864	0.8170512864171755	0.413899119794032	1.0	0.8826212290526823	2	Q9BRJ2	1
+Major sperm protein (MSP) domain [IPR000535]	0.6745203635139652	0.8138834641458971	0.4157117145007118	1.0	0.8826212290526823	3	Q9P0L0,Q8NHP6	2
+EF hand associated, type-2 [IPR013567]	0.7759084791386273	0.8106632514237474	0.4175590824882302	1.0	0.8827155733429946	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.7759084791386273	0.8106632514237474	0.4175590824882302	1.0	0.8827155733429946	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.7759084791386273	0.8106632514237474	0.4175590824882302	1.0	0.8827155733429946	2	Q8IXI1	1
+Aldehyde dehydrogenase domain [IPR015590]	0.4820765864216921	0.8056135150171063	0.4204657304113564	1.0	0.8877073378336308	9	P51649,P51648,Q02252	3
+Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]	0.7691790040376946	0.7852342324291097	0.4323162480260998	1.0	0.8944932188472833	2	P06280	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.6608090641174438	0.7615967402498639	0.4463007209656537	1.0	0.8998317528042191	3	Q9UGJ1	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.6608090641174438	0.7615967402498639	0.4463007209656537	1.0	0.8998317528042191	3	Q9UGJ1	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7607671601615176	0.7537396897943502	0.4510055444965641	1.0	0.901139468443276	2	Q8NF37	1
+Intermediate filament, rod domain [IPR039008]	0.4760959146120272	0.7244599633676639	0.4687833981944413	1.0	0.9094674569579102	8	P07197,Q03252,P20700,Q16352,P07196	5
+Sterile alpha motif domain [IPR001660]	0.4717817160300109	0.7027691159145656	0.4821996469529177	1.0	0.9178149679395384	8	Q9Y6Y8,Q9Y3Z3,Q13586	3
+SUN coiled coil domain 2 [IPR040994]	0.7442799461641989	0.6930434067003521	0.4882823116028825	1.0	0.9197017906287068	2	O94901	1
+Fibronectin type II domain [IPR000562]	0.6410896639032511	0.6877748734554782	0.491594561394634	1.0	0.9197017906287068	3	Q9UBV2	1
+Exportin-2, central domain [IPR013713]	0.6398519017165863	0.6832020287247823	0.4944791908916519	1.0	0.9197017906287068	3	O15397,P55060	2
+EH domain-containing protein, N-terminal [IPR031692]	0.7321668909825014	0.6494180887119475	0.516068175210455	1.0	0.926890618784506	2	Q9H4M9	1
+Domain of unknown function DUF5600 [IPR040990]	0.7321668909825014	0.6494180887119475	0.516068175210455	1.0	0.926890618784506	2	Q9H4M9	1
+Lamin tail domain [IPR001322]	0.6282826730748525	0.6408459995918997	0.5216227432362257	1.0	0.928069813946994	3	P20700	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7288021534320309	0.6374584293460573	0.5238262796061237	1.0	0.9285494080201238	2	O60506	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.6263884214069243	0.6339804819466968	0.5260935599479108	1.0	0.9301612673059076	3	Q9BUJ2,Q1KMD3	2
+CARG-binding factor, N-terminal [IPR012956]	0.7264468371467017	0.6291295999204245	0.5292642134622989	1.0	0.9301612673059076	2	Q99729	1
+FAD/NAD(P)-binding domain [IPR023753]	0.509010158318951	0.6194704709972318	0.5356064690650515	1.0	0.9325139558733004	5	P00390,O95831	2
+FKBP3, basic tilted helix bundle domain [IPR041200]	0.7217362045760487	0.6125808525099887	0.5401535220326463	1.0	0.9329301431856176	2	Q9ULT8	1
+SCP2 sterol-binding domain [IPR003033]	0.6182613134012398	0.6047615423954877	0.545337449982142	1.0	0.9332970237560116	3	P51659	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6115785930662962	0.5810378763803271	0.5612149263407047	1.0	0.9448790506754092	3	P33121,Q6P1M0	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.534542730286468	0.5729960091340423	0.5666473961437555	1.0	0.9512072877904986	4	Q32P28	1
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5345427302864679	0.5729960091340413	0.5666473961437561	1.0	0.9512072877904986	4	Q32P28	1
+ELMO domain [IPR006816]	0.7086137281292105	0.5672858261163563	0.5705200052699928	1.0	0.9565113089160124	2	Q8IZ81	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.6978465679677016	0.53106797343817	0.5953716766152657	1.0	0.9677754743387584	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.6978465679677016	0.53106797343817	0.5953716766152657	1.0	0.9677754743387584	2	Q16836	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.6965006729475106	0.5266043224068313	0.59846838972473	1.0	0.968513049748168	2	P34897	1
+Protein kinase, C-terminal [IPR017892]	0.4619522478963813	0.4984273139563536	0.6181828889499428	1.0	0.9784126279849044	6	P51812	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.6867429340511453	0.49468603592721	0.6208217600558412	1.0	0.9784126279849044	2	P22033	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.4757294206464393	0.4809480350978892	0.6305534318594361	1.0	0.9784126279849044	5	Q8N4Q0	1
+Peptidase M41 [IPR000642]	0.6732839838492612	0.4520061468390396	0.6512645542404214	1.0	0.9784126279849044	2	Q9Y4W6	1
+FCP1 homology domain [IPR004274]	0.5654135037754974	0.4259769021414586	0.6701246768926168	1.0	0.9784126279849044	3	Q05D32	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6635262449528964	0.4221038414477002	0.6729492241465602	1.0	0.9784126279849044	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.6635262449528964	0.4221038414477002	0.6729492241465602	1.0	0.9784126279849044	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6635262449528964	0.4221038414477002	0.6729492241465602	1.0	0.9784126279849044	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6635262449528964	0.4221038414477002	0.6729492241465602	1.0	0.9784126279849044	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.6635262449528964	0.4221038414477002	0.6729492241465602	1.0	0.9784126279849044	2	A0FGR8	1
+L27 domain, C-terminal [IPR014775]	0.6507402422611075	0.38433489459361	0.7007302481702056	1.0	0.9784126279849044	2	Q9NZW5	1
+L27 domain [IPR004172]	0.6507402422611075	0.38433489459361	0.7007302481702056	1.0	0.9784126279849044	2	Q9NZW5	1
+Dehydrogenase, E1 component [IPR001017]	0.6473755047106392	0.3746739968305212	0.7079029333492532	1.0	0.9784126279849044	2	Q02218	1
+Acyl transferase [IPR014043]	0.6456931359354022	0.3698882733578895	0.7114657392649173	1.0	0.9784126279849044	2	P49327	1
+Armadillo repeat-containing domain [IPR006911]	0.62954239569314	0.3255103650372964	0.7447948392397334	1.0	0.9784126279849044	2	Q8N2F6	1
+NOPS [IPR012975]	0.5277684281386567	0.3137062999051259	0.7537441155204267	1.0	0.9784126279849044	3	P23246,Q15233	2
+Immunoglobulin subtype 2 [IPR003598]	0.4287166741242949	0.3021746916810126	0.7625188960996243	1.0	0.9784126279849044	5	P35613	1
+Immunoglobulin subtype [IPR003599]	0.4287166741242949	0.3021746916810126	0.7625188960996243	1.0	0.9784126279849044	5	P35613	1
+Thioesterase domain [IPR006683]	0.605652759084798	0.2653544152100222	0.7907364491181672	1.0	0.9784126279849044	2	O00154	1
+Chromo shadow domain [IPR008251]	0.5045439246045009	0.2522379492947929	0.8008571468580947	1.0	0.9784126279849044	3	P45973,P83916	2
+Chromo domain subgroup [IPR017984]	0.5045439246045009	0.2522379492947929	0.8008571468580947	1.0	0.9784126279849044	3	P45973,P83916	2
+R3H domain [IPR001374]	0.5031975765735397	0.2488748369863926	0.8034576001687959	1.0	0.9784126279849044	3	O15226,Q9H6S0	2
+Immunoglobulin C1-set [IPR003597]	0.4300671759601578	0.2210428354766958	0.825059079900035	1.0	0.9784126279849044	4	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.4300671759601578	0.2210428354766958	0.825059079900035	1.0	0.9784126279849044	4	P10321,P01889	2
+Glutamine amidotransferase [IPR017926]	0.4276094276094291	0.2143346025889752	0.8302861360045071	1.0	0.9784126279849044	4	Q9NRF8,P17812,P49915	3
+Thioredoxin domain [IPR013766]	0.3243123535116098	0.213150534125023	0.8312095496495291	1.0	0.9784126279849044	24	O43396,Q9H1E5,Q9Y320,O43819,Q9H3N1	5
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.4769218243904882	0.1878941663232009	0.8509596158929569	1.0	0.9784126279849044	3	P10586	1
+Peptidase M16, middle/third domain [IPR032632]	0.5693135935397129	0.1873621297635481	0.8513767128406038	1.0	0.9784126279849044	2	O43847	1
+EF-hand, Ca insensitive [IPR014837]	0.4718949848535755	0.1772659838580234	0.8592994685721695	1.0	0.9784126279849044	3	Q13813,P12814	2
+Cyclic nucleotide-binding domain [IPR000595]	0.3893486319943604	0.174085849060076	0.8617979942032776	1.0	0.9784126279849044	5	Q6P4Q7,Q8IY17	2
+Uncharacterised domain CHP00451 [IPR004521]	0.5592193808883001	0.1687098979837417	0.8660248329218576	1.0	0.9784126279849044	2	Q9ULC4	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.4097643097642944	0.1683158741921363	0.866334786220609	1.0	0.9784126279849044	4	P10586,Q13614,P18031	3
+Methyltransferase type 11 [IPR013216]	0.3847158677580716	0.1605982634238094	0.8724098227311643	1.0	0.9784126279849044	5	Q6UX53	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.5541722745625934	0.1598801712665991	0.8729754686155853	1.0	0.9784126279849044	2	Q92922	1
+SMARCC, N-terminal [IPR032450]	0.5541722745625934	0.1598801712665991	0.8729754686155853	1.0	0.9784126279849044	2	Q92922	1
+SMARCC, C-terminal [IPR032451]	0.5541722745625934	0.1598801712665991	0.8729754686155853	1.0	0.9784126279849044	2	Q92922	1
+Ribosomal protein S7 domain [IPR023798]	0.5437415881561285	0.1426776181509821	0.8865447939752364	1.0	0.9784126279849044	2	P46782	1
+Longin domain [IPR010908]	0.4496802423426279	0.1344151407703419	0.8930743096768046	1.0	0.9784126279849044	3	O75396,P51809	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.4496802423426279	0.1344151407703419	0.8930743096768046	1.0	0.9784126279849044	3	O75396,P51809	2
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5383580080753811	0.1343469509213914	0.8931282282619204	1.0	0.9784126279849044	2	Q8WUM0	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.4484735723945763	0.1322813603110349	0.8947617501248506	1.0	0.9784126279849044	3	P00390	1
+Domain of unknown function DUF4217 [IPR025313]	0.4466509592729674	0.1290963530539815	0.8972814077034874	1.0	0.9784126279849044	3	Q9NVP1,Q8NHQ9	2
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.3725159986527436	0.1268347348386	0.8990712033136581	1.0	0.9784126279849044	5	P43243,Q14966,Q15428,P09234	4
+CCAAT-binding factor [IPR005612]	0.4436216762032738	0.1239037024719182	0.9013915213921532	1.0	0.9784126279849044	3	Q03701,Q9BVI4	2
+Brix domain [IPR007109]	0.3704951162007394	0.1214935695592635	0.903300107724313	1.0	0.9784126279849044	5	Q96G21,Q9H7B2,Q9H9Y2,Q9NQ55	4
+PTB/PI domain [IPR006020]	0.5242261103634032	0.1142286076904592	0.9090565746700556	1.0	0.9784126279849044	2	O60343	1
+Metastasis-associated protein MTA1, R1 domain [IPR035170]	0.5205248990578857	0.1093716368683052	0.9129077292683944	1.0	0.9784126279849044	2	Q13330	1
+ELM2 domain [IPR000949]	0.5205248990578857	0.1093716368683052	0.9129077292683944	1.0	0.9784126279849044	2	Q13330	1
+Dynamin GTPase effector [IPR003130]	0.5198519515477915	0.1085066492480931	0.9135938063210274	1.0	0.9784126279849044	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.5198519515477915	0.1085066492480931	0.9135938063210274	1.0	0.9784126279849044	2	P50570	1
+GTPase effector domain [IPR020850]	0.5198519515477915	0.1085066492480931	0.9135938063210274	1.0	0.9784126279849044	2	P50570	1
+S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]	0.5195154777927402	0.1080762343613641	0.9139352199457392	1.0	0.9784126279849044	2	O43865	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.3540160842871238	0.1017762471791729	0.9189342797351868	1.0	0.979097438215431	6	P78417	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.3773068329591791	0.0973729823271652	0.9224301997313517	1.0	0.979097438215431	4	P21912	1
+YTH domain [IPR007275]	0.4227532817233147	0.0915385175075481	0.9270647021481768	1.0	0.979097438215431	3	Q9H6S0,Q7Z739	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.3717171717171698	0.0868739376474894	0.9307717159248124	1.0	0.9800562563845044	4	Q9Y5X3,Q9UNH7,Q13596	3
+Ribosomal L28e/Mak16 [IPR029004]	0.4976446837146789	0.0829977061372205	0.9338533635596208	1.0	0.982050424873035	2	P46779	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.4932705248990701	0.0786440218993479	0.93731577153823	1.0	0.982050424873035	2	Q99584	1
+Histone deacetylase domain [IPR023801]	0.4905787348586906	0.0760698745323327	0.9393635073155496	1.0	0.982050424873035	2	Q92769	1
+FAST kinase leucine-rich [IPR010622]	0.485868102288023	0.0717538509590724	0.9427977997002516	1.0	0.982050424873035	2	Q969Z0	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.485868102288023	0.0717538509590724	0.9427977997002516	1.0	0.982050424873035	2	Q969Z0	1
+RAP domain [IPR013584]	0.485868102288023	0.0717538509590724	0.9427977997002516	1.0	0.982050424873035	2	Q969Z0	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4049141703130211	0.0684869898956807	0.9453979763179858	1.0	0.982050424873035	3	Q8WVV9,P14866	2
+Ubiquitin conjugation factor E4, core [IPR019474]	0.481493943472419	0.0679566300219184	0.9458201586601872	1.0	0.982050424873035	2	Q14139	1
+DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]	0.4609690444145368	0.0526879232411815	0.9579805615183036	1.0	0.982050424873035	2	Q14181	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.4320323014804813	0.0374228710412491	0.9701478369873248	1.0	0.9895507937270712	2	Q9NVE7	1
+MRH domain [IPR044865]	0.370918882531129	0.0354815287596455	0.9716957750151314	1.0	0.9896522723835248	3	P14314,P20645	2
+Glycosyl hydrolase, family 13, catalytic domain [IPR006047]	0.426648721399731	0.0352700504522868	0.9718644047426446	1.0	0.9896522723835248	2	P08195	1
+Condensin complex subunit 1, C-terminal [IPR032682]	0.4162180349932743	0.0316230401750592	0.9747726691739588	1.0	0.9913986170591008	2	P42695	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.4125168236877502	0.0304829637149344	0.9756818800537213	1.0	0.9914774771156122	2	Q92945	1
+Ribosomal protein L18e/L15P [IPR021131]	0.3581285762369515	0.026390849879338	0.9789455923481378	1.0	0.9938756394676984	3	P46776,Q9P015	2
+CS domain [IPR007052]	0.3129073098863951	0.0243904789381418	0.9805411427747746	1.0	0.9941237260756094	8	Q9P035	1
+G-protein, beta subunit [IPR001632]	0.3536339165545118	0.0202638191687339	0.9838329179775194	1.0	0.9961703475479796	2	Q13112	1
+Pumilio homology domain [IPR033133]	0.3516150740242308	0.0201015325407231	0.9839623776025386	1.0	0.9961703475479796	2	Q14671	1
+Rab-GTPase-TBC domain [IPR000195]	0.3210916442048523	0.0194660456682483	0.9844693235395504	1.0	0.996271560159082	6	Q9Y3P9,Q8TC07,Q9UPU7,O60343,Q9NVG8	5
+Importin-beta, N-terminal domain [IPR001494]	0.293617017321403	0.0179273160159432	0.9856968374840532	1.0	0.9971015942813892	14	Q14974,Q92973,Q8TEX9,O43592,Q96P70	5

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Syntaxin [IPR045242]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}