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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Ferroptosis 0.6548834915292925 2.761681781123 0.0057504495182001 0.965340672864902 0.2074792856356592 21 P45880,Q9NZ45,Q9Y277,Q6P1A2,P09601,Q96QD8,P16435 7
Electron transport chain oxphos system in mitochondria 0.4931033656936826 2.744965903408754 0.0060517184960742 0.970953893770187 0.2074792856356592 57 P00846,O75306,P13073,P14406,O75880,P24539,Q7KZN9,O43676,P21912,P20674,O75964,Q9UDW1,O14949,P12236,O75438,O96000,P14927,P03886,Q9Y6M9,P00403,P22695,O14548 22
Sphingolipid metabolism in senescence 0.7709701938237902 2.6577700082256848 0.0078659552667113 0.9899881222472404 0.2074792856356592 12 Q13510,Q06136,P04062,P16278,Q96G23 5
Sphingolipid metabolism overview 0.8078311270362598 2.539725446585704 0.0110939519348636 0.9985024399587842 0.2309919277866247 9 Q13510,O95470,Q16739,Q06136,Q96G23,P27544 6
Sphingolipid metabolism integrated pathway 0.7784566878773361 2.4936556576251276 0.0126435133981706 0.9993997495586542 0.2457056103711154 10 Q13510,O95470,Q16739,Q06136,Q96G23,Q16880,P27544,O15269 8
Cholesterol metabolism with bloch and kandutschrussell pathways 0.5868337238686449 2.298193139834742 0.0215507989798149 0.9999969533753204 0.3221568155187719 21 P14324,Q15392,Q9BWD1,Q14739,P48449,Q15800,O76062,Q16850,P37268 9
Degradation pathway of sphingolipids including diseases 0.8527035125947424 2.261063697349171 0.0237553129690839 0.99999918207705 0.3345428326685843 6 P06280,P16278,O43681,P06865 4
Sphingolipid pathway 0.7165295323214388 2.1820608345833596 0.0291050432406834 0.9999999667785228 0.3713060378934167 10 Q13510,O95470,Q16739,Q06136,P04062,Q96G23 6
Glycosaminoglycan degradation 0.796941797047926 2.0196211469758234 0.0434226999207287 0.9999999999942484 0.4520613223890157 6 P15586,P16278,P54802,P06865 4
Metabolism of spingolipids in er and golgi apparatus 0.8589743589743536 1.958586063168523 0.0501612830591233 0.9999999999999069 0.4821207829589566 5 O95470,Q16739,Q10472,Q06136 4
Mitochondrial complex iv assembly 0.5972569376848959 1.7968438690419932 0.0723604097405921 1.0 0.52332865172351 13 Q9Y2R0,Q7KZN9,P13073,P00403,P14406 5
Prostaglandin and leukotriene metabolism in senescence 0.955887584489506 1.7618930263758326 0.0780873730852733 1.0 0.5355875118672279 2 P09960 1
Nephrotic syndrome 0.6035517578518041 1.7460852815491497 0.0807961339630904 1.0 0.5477226290753693 12 Q96D53,O75844,Q9BT22,Q14108 4
Familial partial lipodystrophy fpld 0.7239903684726947 1.6943012677344966 0.0902080498068811 1.0 0.5611755268889815 6 O60725 1
Endothelin pathways 0.652707785579216 1.6928651863849618 0.0904811312651188 1.0 0.5611755268889815 8 P00403,P42892,P63096 3
Nonalcoholic fatty liver disease 0.4102352951658357 1.681128713327518 0.0927379162687762 1.0 0.5669145640924736 49 Q9P0J0,P14406,O14949,O43676,P21912,P14927,Q86Y39,P20674,O75438,O96000,Q9Y6M9,P00403,O75306,P22695,P13073,Q9UDW1 16
Oxidation by cytochrome p450 0.7890892481868836 1.6690950800354971 0.0950985382000721 1.0 0.5715716265014648 5 O43169,Q6UW02,P16435 3
Overlap between signal transduction pathways contributing to lmna laminopathies 0.5853052172090047 1.641333839477526 0.1007281353176099 1.0 0.587245028901666 12 O60725,P42167,P42166,P55209,O75844 5
Proteoglycan biosynthesis 0.8989217655697217 1.6195051669673604 0.1053386156683595 1.0 0.598973068687384 4 Q8TB61 1
Ketogenesis and ketolysis 0.6976949222317355 1.574654608309791 0.1153361906048633 1.0 0.6226018437281048 6 P23786 1
Progeriaassociated lipodystrophy 0.610414808223806 1.5459607038788867 0.1221140584686764 1.0 0.6468401520800577 9 O60725 1
S1p receptor signal transduction 0.686202526284521 1.5220183638308211 0.1280044794070689 1.0 0.6468401520800577 6 Q13510,P63096 2
Mitochondrial complex iii assembly 0.5814585608462806 1.4643420322571068 0.1431005180824738 1.0 0.6838328036236249 10 O14949,P14927,Q9BRT2,P22695,P08574,Q9UDW1 6
Heme biosynthesis 0.738842736147717 1.4569291721670996 0.1451359324186736 1.0 0.6879207203259082 5 P22830,P06132 2
Eicosanoid synthesis 0.8779793667733936 1.437311952909638 0.1506293740180564 1.0 0.6888774703825657 2 P09960 1
Ciliopathies 0.520645503228604 1.4215334914650315 0.1551617242505121 1.0 0.6888774703825657 14 O43924,Q13432 2
Calcium regulation in cardiac cells 0.4226447324214783 1.3703000922602229 0.1705932442819346 1.0 0.7011699187433849 25 P16615,Q14012,P63218,P20020,Q9UBI6,P04899,P62942,P23634,P63096,P10644,Q13555,P0DP25 12
Adipogenesis 0.5075150362230028 1.3390129633514205 0.1805664527771044 1.0 0.7210290545825474 14 Q9NZ45,O00767,P43490,O14654,P14174,P42224,O75844 7
Omega3 omega6 fatty acid synthesis 0.64239979299029 1.3198226599575011 0.1868942341614403 1.0 0.7228252082461972 6 Q15067,O15254 2
Kennedy pathway from sphingolipids 0.8203888527356615 1.3151882699837494 0.1884466363931258 1.0 0.7228252082461972 4 O95470 1
Vitamin d metabolism 0.9030213020337304 1.3013559968951058 0.1931366281455977 1.0 0.7336664003170349 3 P38435 1
Angiopoietinlike protein 8 regulatory pathway 0.4222441831668941 1.286849653969957 0.1981466961992988 1.0 0.7361101234751545 24 Q15418,P42345,P41440,O00767,O14654,O75955,P51812,Q9UPT5,Q14254 9
Mitochondrial immune response to sarscov2 0.5486379007957941 1.28344126404932 0.199337525020518 1.0 0.7361101234751545 10 Q86UT6,Q99623,Q9Y6M9,Q7Z434,Q9BQ95 5
Urea cycle and related diseases 0.8392031305585238 1.2757255225758268 0.2020525631228134 1.0 0.7361101234751545 2 Q9Y619 1
Influence of laminopathies on wnt signaling 0.5705301366828873 1.269319978124832 0.2043269637721692 1.0 0.7361101234751545 8 O60725,O75844 2
Hostpathogen interaction of human coronaviruses interferon induction 0.6920198127176723 1.257222860802797 0.2086729474549415 1.0 0.7452539027389754 5 Q7Z434,P42224 2
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8902146708855008 1.2536944744541152 0.2099530770956232 1.0 0.7452539027389754 3 P09601 1
Dna replication 0.4158374760613057 1.234010209457849 0.2171990999169017 1.0 0.7521093561440072 24 P33991,Q9Y619 2
Ccl18 signaling pathway 0.5359173343652937 1.2129328203034928 0.2251555062525581 1.0 0.7721509420308317 10 P00403,Q86UE4,P07196 3
Cholesterol biosynthesis with skeletal dysplasias 0.6716796207334444 1.1702203153939403 0.2419123193869179 1.0 0.798404608659013 5 Q14739,Q15392 2
Mitochondrial long chain fatty acid betaoxidation 0.4926497633380144 1.1670523294521713 0.2431892374477273 1.0 0.798404608659013 13 P23786 1
Alzheimers disease 0.3381422858259679 1.1521230083632985 0.2492705296371342 1.0 0.798404608659013 77 P16615,Q92542,P45880,P28072,P12236,O95197,Q9Y277,O14654,Q9NQC3,P20618,P21796,P28070,P04350,P49721,P68371,P07437,P05067 17
Camkk2 pathway 0.5235969232130218 1.1445220537027998 0.2524071971960961 1.0 0.798404608659013 10 O76024,Q14012,P09601,Q9Y3D6 4
Statin inhibition of cholesterol production 0.775909895972453 1.1423690076756443 0.2533006680743694 1.0 0.798404608659013 4 Q8WTV0,P37268 2
Spinal cord injury 0.4510003784319594 1.1332288557288417 0.2571181593700267 1.0 0.8016036733300832 18 Q08722,P62942,Q9NQC3 3
Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.5247682046613005 1.087391510358136 0.2768638215058701 1.0 0.8406854580100117 9 Q15118 1
Mitochondrial complex i assembly model oxphos system 0.3817583853897554 1.0755178168056374 0.2821429597646609 1.0 0.8415721219312085 30 Q9P0J0,O43676,Q8IUX1,O75438,Q9NW81,P03886,O96000,O75306,Q96CU9,Q9BQ95 10
Sars coronavirus and innate immunity 0.786197082888656 1.0570815929043704 0.2904743511613348 1.0 0.8415721219312085 2 Q7Z434 1
Alzheimers disease and mirna effects 0.3286976305724663 1.0560204894681318 0.2909588539682515 1.0 0.8415721219312085 79 P16615,Q92542,P45880,P28072,P12236,O95197,Q9Y277,O14654,Q9NQC3,P20618,P21796,P28070,P04350,P49721,P68371,P07437,P05067 17
Pathways of nucleic acid metabolism and innate immune sensing 0.6412648258836593 1.0403145997519638 0.298193763412395 1.0 0.8439173013078947 5 O00584 1
Oxidative phosphorylation 0.3695039787838601 1.0304149223465462 0.3028152712256853 1.0 0.848756265021993 34 P03886,O75964,P00846,P24539 4
Pkcgamma calcium signaling pathway in ataxia 0.7773034507292839 1.0208634607048637 0.3073191328316009 1.0 0.85725863368815 2 Q15118 1
Cholesterol biosynthesis pathway 0.4964191093783468 0.993567882285966 0.3204332870069879 1.0 0.8686494000745335 10 P37268,Q15800,P48449,Q16850 4
Sting pathway in kawasakilike disease and covid19 0.7627178939879113 0.961880273596782 0.3361097486400011 1.0 0.8686494000745335 2 Q86UT6 1
G protein signaling pathways 0.4686026891370449 0.9559230813563584 0.3391110968295936 1.0 0.8709329050733615 12 O43823,P63218,Q9UBI6,Q92667,P04899,P63096 6
Inclusion body myositis 0.8045997387614587 0.9386210553123072 0.3479253385255632 1.0 0.8775796250491955 3 Q92542 1
Vitamin d receptor pathway 0.4857083383342623 0.9342248492694608 0.3501879201689131 1.0 0.8775796250491955 10 P08183,Q96KA5,Q5VV42,Q92604 4
G1 to s cell cycle control 0.3945836881519797 0.931121874140021 0.351790524744989 1.0 0.8775796250491955 22 P33991 1
Nocgmppkg mediated neuroprotection 0.7173637572502518 0.9171371939089006 0.3590707530417254 1.0 0.8775796250491955 4 P07196 1
Myometrial relaxation and contraction pathways 0.424440848178777 0.9045879859147956 0.3656837024371202 1.0 0.8775796250491955 17 P16615,P63218,Q9UBI6,P78417,Q13555,P19174,P0DP25 7
Metapathway biotransformation phase i and ii 0.4047988813603288 0.9019669940852008 0.367074401146886 1.0 0.8775796250491955 20 Q7LGA3,Q6UW02,P07099,Q16850,Q8NCH0,P21964 6
Purinergic signaling 0.7803413252361888 0.8515208149280663 0.3944801057097509 1.0 0.8803109219914925 3 P63096 1
Neuroinflammation 0.7796381950528 0.849018124285873 0.3958712072378745 1.0 0.8803109219914925 3 P00403 1
Caloric restriction and aging 0.7736020930098921 0.8275901342479144 0.4079026573855202 1.0 0.8803109219914925 3 P43490 1
Thermogenesis 0.364163129912854 0.807906443496424 0.4191444417072598 1.0 0.8848727999415863 24 P23786,O43772 2
Joubert syndrome 0.4190500927971084 0.804680808097456 0.4210038972835188 1.0 0.8848727999415863 15 O43924,Q13432 2
Vitamin a and carotenoid metabolism 0.6833866744309992 0.7892234323681966 0.4299814287922716 1.0 0.8913439372787351 4 Q8WTV0 1
Cytosolic dnasensing pathway 0.4539863185271449 0.7599346511853726 0.4472936477600786 1.0 0.8935224202173894 10 Q86UT6 1
Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.4933372233565378 0.7300559926647463 0.4653559595150724 1.0 0.8966518881669963 7 Q15118,Q13418 2
Fatty acid betaoxidation 0.3860216927705152 0.721622760518313 0.4705264417174266 1.0 0.8966518881669963 19 P23786 1
Reninangiotensinaldosterone system raas 0.7409252669039144 0.7136035274613536 0.4754723757129835 1.0 0.8966518881669963 3 Q14012,P0DP25 2
Omega9 fatty acid synthesis 0.5101416472772393 0.7091772646743675 0.4782144802634391 1.0 0.8966518881669963 6 O00767 1
Novel intracellular components of rigilike receptor rlr pathway 0.4532943195407928 0.7058207731847335 0.4802996019385572 1.0 0.8966518881669963 9 Q86UT6 1
T cell receptor and costimulatory signaling 0.729181494661931 0.673611952356423 0.5005580522918307 1.0 0.906289889708501 3 Q15118,P19174 2
Eicosanoid metabolism via lipooxygenases lox 0.4962331280003598 0.6471963604950042 0.517504866520583 1.0 0.9198333450655484 6 Q15067,P09960 2
Steroid biosynthesis 0.6773390252579227 0.6327022155546241 0.5269281227790961 1.0 0.9309063502430698 2 Q99829 1
Envelope proteins and their potential roles in edmd physiopathology 0.3821238657867305 0.6219345935329554 0.533984876956163 1.0 0.9348744242205498 17 P42167,P50402,Q14739,P42166 4
Interactions between loxl4 and oxidative stress pathway 0.6712913553895486 0.6108559035273915 0.5412949799925688 1.0 0.9368488094643236 2 Q9BQ95 1
Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7088967971530392 0.6059979966421873 0.5445160835300464 1.0 0.9368488094643236 3 Q15118,P42345 2
Gastric cancer network 2 0.4081075756084987 0.6054154618855724 0.5449029800121461 1.0 0.9368488094643236 12 Q14739 1
Cellular proteostasis 0.6313409456859099 0.6006757844613234 0.5480559508116816 1.0 0.9369988836457782 4 Q9UHV9,P61758 2
Type i interferon induction and signaling during sarscov2 infection 0.7003511613596904 0.5781318530037312 0.5631751032232362 1.0 0.942540878322212 3 Q7Z434 1
Tryptophan metabolism 0.3714486402733987 0.5088034643781092 0.6108899908396621 1.0 0.9782044212819188 15 P51648,Q15392 2
Serotonin htr1 group and fos pathway 0.409586709174757 0.483293959338652 0.6288870285446722 1.0 0.9815559780001778 9 P63096 1
Pdgfrbeta pathway 0.4271015647740747 0.3582035050127388 0.7201910244236622 1.0 1.0 6 P42224,P19174 2
Genes related to primary cilium development based on crispr 0.352702033845318 0.3109258410831499 0.7558569991227624 1.0 1.0 12 Q10713,Q96J42,O95684 3
Mevalonate pathway 0.5866905983156763 0.2563315374585005 0.797694847158317 1.0 1.0 3 Q9BWD1 1
Insulin signaling 0.280983029846342 0.2351642378819862 0.8140812617320086 1.0 1.0 34 Q14254,Q15418,P41440,P42345,O14654,O75955,Q9H4M9,P51812,Q12846,P10586,P18031 11
Bdnftrkb signaling 0.3805180377223442 0.2343754475447668 0.8146935178794834 1.0 1.0 7 P19174,P62993,Q15418,P42345 4
Intracellular trafficking proteins involved in cmt neuropathy 0.348366435329034 0.2319050227938331 0.8166117832446873 1.0 1.0 10 Q9NR77 1
Epo receptor signaling 0.3745605034048122 0.2122499602978703 0.8319120318499356 1.0 1.0 7 Q15118,P42224 2
Cancer immunotherapy by pd1 blockade 0.5275702596940717 0.1939767575309886 0.8461940810382067 1.0 1.0 2 P04439 1
Glycerophospholipid biosynthetic pathway 0.3671341215397633 0.1854925682527526 0.852842708797751 1.0 1.0 7 Q8WUK0,O00116 2
Synaptic signaling pathways associated with autism spectrum disorder 0.3728545056056233 0.1681331091590682 0.8664785627567295 1.0 1.0 6 Q05086,Q15382,P42345 3
Chemokine signaling pathway 0.2998922310078389 0.1333738749000866 0.8938977056083501 1.0 1.0 16 P63218,Q9UBI6,P04899,P42224,P63096 5
Thyroid stimulating hormone tsh signaling pathway 0.2953616108322862 0.112792329170729 0.9101951999686796 1.0 1.0 16 P42224,P04899,P63096,Q15418 4
Robo4 and vegf signaling pathways crosstalk 0.4567769477054584 0.0839050722390919 0.9331319067206224 1.0 1.0 2 O94813 1
Translation inhibitors in chronically activated pdgfra cells 0.2876017204252611 0.076431422898202 0.939075870857006 1.0 1.0 15 P23588,Q15118,Q15418 3
Oligodendrocyte specification and differentiation leading to myelin components for cns 0.4382781928139532 0.0657715966286288 0.9475596698630872 1.0 1.0 2 P09543 1
Circadian rhythm genes 0.2561384694383669 0.0516636347996244 0.9587967137491252 1.0 1.0 37 Q06210,Q15233,Q05086,Q9NRV9,P43490,Q9Y2W1,Q8WXF1,P54802,P00813,P04818,P23246 11
Vitamin b12 disorders 0.4587188612099541 0.0479999094553672 0.9617163147694644 1.0 1.0 3 Q99707,Q96EY8 2
Ethanol effects on histone modifications 0.2953748537113402 0.036566757141624 0.970830449751962 1.0 1.0 10 P41440,O94788,P04818 3
Glucocorticoid receptor pathway 0.3965824136703475 0.0254993472704097 0.9796566691218928 1.0 1.0 4 P07900,Q15185,Q86UP2 3
Il10 antiinflammatory signaling pathway 0.3951217121986564 0.0239401612584177 0.9809003394018208 1.0 1.0 4 P42224,P09601 2
Primary focal segmental glomerulosclerosis fsgs 0.2719650095607523 0.0177897751719334 0.9858065617014432 1.0 1.0 16 P08670,Q14108 2
Praderwilli and angelman syndrome 0.3344524429750949 0.0170412510849763 0.9864037069359062 1.0 1.0 5 Q05086 1
Pdgf pathway 0.2841303933198573 0.0158626732739124 0.9873439486658052 1.0 1.0 11 P00403,P19174,P42224 3
Mrna protein and metabolite inducation pathway by cyclosporin a 0.4070272729389877 0.0120794888144017 0.9903621967549854 1.0 1.0 3 P08195 1
Photodynamic therapyinduced ap1 survival signaling 0.3095831848949008 0.0095793205634428 0.99235692491203 1.0 1.0 6 Q16539,Q07820,P04637,P07900,P49327 5
Nad metabolism 0.3980671946662948 0.008009643758599 0.9936092972394988 1.0 1.0 3 P43490 1
Nad biosynthetic pathways 0.3980671946662948 0.008009643758599 0.9936092972394988 1.0 1.0 3 P43490 1
Mecp2 and associated rett syndrome 0.2675208512439481 0.0074879687145184 0.9940255212021444 1.0 1.0 18 Q05086,P31943,P35637,P42345,Q13451 5