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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:31ff37140e1e2ed1b8c7f038959f926da8726e872864fdba50e71e10337813e9
+size 64382

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2813,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.175438596491228
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C231/C231_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.8480427046263385	1.741356120287536	0.0816211746892254	0.9921972781853606	0.3578774582527578	3	Q9HB40,P10619	2
+Histidine acid phosphatase active site [IPR033379]	0.9156883671291384	1.1578186830325985	0.2469380373934928	0.9999999046434406	0.5335507017852347	2	Q9NPH0	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.5489149768765682	0.099119003357468	0.9210437838891808	1.0	0.9883667053021504	2	P18669	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.3319088319088326	0.0363203313734009	0.9710269385424636	1.0	0.9883667053021504	5	P61088,P68036,P61086,P60604	4

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CASP3", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR6", "NCEH1", "NEK9", "NME1", "PAK2", "PBK", "PGAM1", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRPF4B", "PTK2", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CTSA", "PGAM1", "SCPEP1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:dfcb5b331d710180ede518608bb5dc0c092ba5c59348eec800153aa3c6ea0166
+size 63515

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	11	35	1.993563235659723	0.046199806466824	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0019857800802031	0.3175327074700926	0.0413282647695778	0.0114639670330544	0.0014057503196826

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2813,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 3.838709677419355
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C231/C231_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4834955695056497	1.993563235659723	0.046199806466824	0.7692298710135685	0.3638122632879432	35	O43852,P41208,Q96AY3,Q9NWM8,P0DP25,Q6NUK1,Q14257,O95202,Q9Y680,Q9BPX6,P80303	11
+Peptidase M16, zinc-binding site [IPR001431]	0.5979581903984439	1.1217041945341606	0.2619882325147946	0.9999187240815742	0.5682030794633631	5	P22695	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPNS1", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2", "VRK1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "LETM1", "MICU1", "NUCB2", "RCN2", "SLC25A24", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Thioredoxin, conserved site [IPR017937]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:85b281bdbaca09f2765b172a9465b71af09ffea081c12a4b31c65e14477b0ef5
+size 66155

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	4	6	1.9983579969328051	0.0456778619387676	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0017772270293556	1.0	0.1191939669275513	0.0373951204607401	0.0027426851014433

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2813,
+    "annotations_size": 264,
+    "title": "Average number of proteins per term",
+    "value": 2.492424242424242
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C231/C231_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7710617577151713	1.9983579969328056	0.0456778619387676	0.9999956400689396	0.7321518839929796	6	Q86Y82,Q9P2W9,O15400,Q13190	4
+Sterol reductase, conserved site [IPR018083]	0.8718861209964379	1.8400049398329104	0.0657675120868463	0.999999984147018	0.7321518839929796	3	Q14739,O76062	2
+Tetraspanin, conserved site [IPR018503]	0.993240839558876	1.4562234246378565	0.1453308660172263	1.0	0.7959135972026082	2	O60637	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.9526858769121314	1.299688028935344	0.1937079149388298	1.0	0.8409293798514365	2	P11279	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.7413391406913463	1.2937844720419072	0.1957398777296224	1.0	0.8409293798514365	3	Q8N4Q0	1
+Haem oxygenase conserved site [IPR018207]	0.9498399146211324	1.2887328132350353	0.1974909907226858	1.0	0.8409293798514365	2	P30519	1
+Thioredoxin, conserved site [IPR017937]	0.5833568565925795	1.241946381683009	0.2142563455967687	1.0	0.8613028717413548	12	Q9H3N1,Q99757,Q9H1E5,O43396,Q96JJ7	5
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5942901555969173	1.1979660908690386	0.2309302182306674	1.0	0.8613028717413548	8	P49721	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.5255405801770117	0.9288344615592464	0.3529748819956619	1.0	0.9850276332826798	12	Q53GQ0,Q8NBN7,Q06136	3
+ABC transporter-like, conserved site [IPR017871]	0.5047076797653964	0.7480289598307971	0.4544426898062599	1.0	0.992921559312754	8	P08183,Q03518,O75027	3
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.992921559312754	2	Q06481	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.992921559312754	2	Q06481	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.992921559312754	2	Q06481	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.5686551005404265	0.5897231932311416	0.5553762432246159	1.0	0.992921559312754	3	P27824	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.6798292422625472	0.3547879695618538	0.722748441749733	1.0	0.9992671501264128	2	P14174	1
+S100/Calbindin-D9k, conserved site [IPR001751]	0.6542155816435515	0.2899134582637078	0.7718824453831754	1.0	0.9992671501264128	2	P60903	1
+Intermediate filament protein, conserved site [IPR018039]	0.4046144178897806	0.2784203378637418	0.7806897091166842	1.0	0.9992671501264128	8	P07196,P48681,Q16352,P08670	4
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.6488794023479272	0.277246396861056	0.7815909158231455	1.0	0.9992671501264128	2	O60573	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.6321593738883049	0.2395453606254928	0.8106827273724653	1.0	0.9992671501264128	2	Q16836	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4519572953736651	0.2143815185422244	0.8302495527089608	1.0	0.9992671501264128	3	P07900,P14625	2
+Ribosomal protein S9, conserved site [IPR020574]	0.6036997509783094	0.1825695643273587	0.8551357670680235	1.0	0.9992671501264128	2	P82933	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4238105469733966	0.1489956516833808	0.8815570641207731	1.0	0.9992671501264128	3	Q96CW1	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.4067615658362943	0.115174246004788	0.9083070115229568	1.0	0.9992671501264128	3	O43175,Q13363	2
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.519388118107444	0.0679119365350361	0.9458557367110004	1.0	0.9992671501264128	2	P15880	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.3612099644128148	0.0464048041740413	0.9629876074627108	1.0	0.9992671501264128	3	P22059,Q9BZF1	2
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.4909284951974514	0.0458897234828129	0.9633981450222396	1.0	0.9992671501264128	2	P24534	1
+Cullin, conserved site [IPR016157]	0.3296765919131316	0.030991758968274	0.9752761119080344	1.0	1.0	5	Q93034,Q13620	2
+DnaJ domain, conserved site [IPR018253]	0.3374812163837126	0.024442567181896	0.980499594755905	1.0	1.0	9	Q9NVH1	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATP5C1", "ATP5O", "ATP7A", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BDH2", "BOP1", "BPNT1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG3", "DMD", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L5", "EPDR1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HINT2", "HLA-A", "HLA-B", "HLA-F", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMMP2L", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDSR", "KIF11", "KIF14", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "OSBP", "OSBPL11", "OSBPL8", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "REL", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SORD", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX16", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP10", "USP14", "USP28", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "AP2M1", "APLP2", "CANX", "CTBP1", "CUL4B", "CUL5", "DNAJC11", "EEF1B2", "EIF4E2", "HADH", "HMOX2", "HSD17B12", "HSP90AA1", "HSP90B1", "INA", "KDSR", "LAMP1", "LBR", "MIF", "MRPS9", "NEFL", "NES", "OSBP", "OSBPL8", "PHGDH", "PSMB2", "RDH13", "RPS2", "S100A10", "STX12", "STX18", "STX5", "STX7", "TAP1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TSPAN3", "TXN2", "TXNL1", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Band 7 domain [IPR001107]", "2": "Thioredoxin domain [IPR013766]", "3": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "4": "Importin-beta, N-terminal domain [IPR001494]", "5": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:e32d3892d5f55be40668e1c8e08156e2cae2069dd69ddc231e118a4c42f6bb35
+size 127949

interpro_domain/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+GOLD domain [IPR009038]	4	5	2.1587641680232843	0.0308684676892991	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0017772270293556	1.0	1.0	1.0	0.0027426851014433

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2813,
+    "annotations_size": 2301,
+    "title": "Average number of proteins per term",
+    "value": 2.060408518035637
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C231/C231_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,158 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+GOLD domain [IPR009038]	0.8226495726495665	2.1587641680232843	0.0308684676892991	1.0	0.5234654876705443	5	Q15363,Q9Y3B3,P49755,Q9Y3A6	4
+LEM domain [IPR003887]	0.7608754314888969	1.951922540677796	0.0509474016844522	1.0	0.5234654876705443	6	P42167,Q86XL3	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7568731152733961	1.9336122353827885	0.0531608217773391	1.0	0.5234654876705443	6	O15173,O43169,O00264	3
+EF-hand domain [IPR002048]	0.4830606351733008	1.8947245025861577	0.0581289098168873	1.0	0.5234654876705443	41	Q8NF37,P80303,O43852,Q9NWM8,Q8IYU8,Q8IXI1,Q6NUK1,O95202,O75340,P0DP25,Q9Y680,P41208,Q96AY3,Q9UBV8,Q8IXI2,Q14257,Q9UJS0,Q66K14,Q9BPX6,Q9BRK5	20
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7516983443596026	1.8409619040228256	0.0656271416231535	1.0	0.5234654876705443	5	P16615,P23634,P05023	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7516983443596026	1.8409619040228256	0.0656271416231535	1.0	0.5234654876705443	5	P16615,P23634,P05023	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7303403931578061	1.837317035614898	0.0661631064370109	1.0	0.5234654876705443	7	Q9HD20,P16615,P23634,P05023	4
+Immunoglobulin-like domain [IPR007110]	0.7176428453584358	1.836073468246881	0.0663467916537499	1.0	0.5234654876705443	9	P35613,Q08722	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.7239190491178409	1.8070773726785496	0.070750216139948	1.0	0.5234654876705443	7	Q86Y82,Q9UNK0,O15400,Q13190	4
+Immunoglobulin subtype [IPR003599]	0.8398904702490309	1.7657438317169336	0.0774388355960058	1.0	0.5234654876705443	4	P35613	1
+Immunoglobulin subtype 2 [IPR003598]	0.8398904702490309	1.7657438317169336	0.0774388355960058	1.0	0.5234654876705443	4	P35613	1
+Reticulon [IPR003388]	0.8390886436454422	1.7624995179104133	0.0779849377627841	1.0	0.5234654876705443	4	Q9NQC3,O75298,O95197	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.8216447134211475	1.6917064505264112	0.0907019579182368	1.0	0.5269908250485126	4	P08183,Q03518,O75027	3
+GMP phosphodiesterase, delta subunit [IPR008015]	0.8245551601423438	1.6435609563472555	0.1002669244208087	1.0	0.5415826128926783	3	A6NIH7,O43924	2
+Band 7 domain [IPR001107]	0.673017425388398	1.5641421464328034	0.1177841900778464	1.0	0.5663154418227804	7	Q14254,P35232,Q99623,O75955,Q9UJZ1	5
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.802491103202866	1.5512173271687448	0.1208496111201693	1.0	0.5663154418227804	3	Q96RQ1,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.802491103202866	1.5512173271687448	0.1208496111201693	1.0	0.5663154418227804	3	Q96RQ1,Q9Y282	2
+SUN domain [IPR012919]	0.79641488341303	1.5257187491843862	0.1270799230987369	1.0	0.5813338032807033	3	O94901	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6766560619500757	1.4939788630013235	0.1351811439903634	1.0	0.5936103288584469	5	P09960,Q9UIQ6	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6766560619500757	1.4939788630013235	0.1351811439903634	1.0	0.5936103288584469	5	P09960,Q9UIQ6	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7552189336965349	1.4188845508979693	0.1559326770607718	1.0	0.6436049613235708	4	Q15629	1
+Tim10-like [IPR004217]	0.7533985650280267	1.4113490781733884	0.158141709892976	1.0	0.6455191026681532	4	P62072,Q9Y5J9	2
+Syntaxin, N-terminal domain [IPR006011]	0.7393669250886674	1.3531889778521862	0.1759952655809746	1.0	0.669582831953602	4	Q86Y82,O15400	2
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.7548042704626415	1.350564328909308	0.1768350339242208	1.0	0.669582831953602	3	Q9BYT8,Q99797	2
+Marvel domain [IPR008253]	0.9494841693347578	1.2873638022700933	0.1979675148288999	1.0	0.6811693917773548	2	O43760	1
+Exportin-2, central domain [IPR013713]	0.7387995881126146	1.2830761889925029	0.1994653849212437	1.0	0.6820056238438285	3	O15397	1
+Dynamin, GTPase domain [IPR001401]	0.7345437398071526	1.265133062592274	0.2058236326283902	1.0	0.6940692818942392	3	O60313	1
+ERAP1-like C-terminal domain [IPR024571]	0.7273178929230582	1.234677732224652	0.2169504664888712	1.0	0.7111154179357447	3	Q9UIQ6	1
+NOPS [IPR012975]	0.7099644128113822	1.161627416084195	0.2453868407184511	1.0	0.7371215672234416	3	P23246,Q8WXF1	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5845271852488607	1.1307092021219762	0.2581775069362275	1.0	0.7502510512858216	7	O60313,O95140,Q8IWA4	3
+Dynamin, N-terminal [IPR045063]	0.5845271852488607	1.1307092021219762	0.2581775069362275	1.0	0.7502510512858216	7	O60313,O95140,Q8IWA4	3
+Thioredoxin domain [IPR013766]	0.4620628424183285	1.1230355115031865	0.2614224127693036	1.0	0.7544777521381966	25	Q9H3N1,Q9Y320,Q99757,Q9H1E5,O43396,O43819,Q6ZRP7,Q96J42,Q96JJ7	9
+Major sperm protein (MSP) domain [IPR000535]	0.6977682283824591	1.1104121507871894	0.2668214646078175	1.0	0.7544777521381966	3	O95292	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6740620292598327	1.0817263674798037	0.2793741332655537	1.0	0.774505880294023	4	O60749	1
+ADCK3-like domain [IPR034646]	0.8911419423692672	1.0646132126886072	0.2870509982056759	1.0	0.7886767960546592	2	Q8NI60	1
+ABC1 atypical kinase-like domain [IPR004147]	0.8911419423692672	1.0646132126886072	0.2870509982056759	1.0	0.7886767960546592	2	Q8NI60	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8826040554962667	1.032431687717989	0.3018699338767718	1.0	0.7971470830005252	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8826040554962667	1.032431687717989	0.3018699338767718	1.0	0.7971470830005252	2	Q13505	1
+Polyketide synthase, enoylreductase domain [IPR020843]	0.5661877505458199	1.025575141462683	0.3050918897933008	1.0	0.7995631417020332	6	Q99536,P49327,Q8N4Q0	3
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.876200640341517	1.0083902776636966	0.3132671384878374	1.0	0.8108297926439976	2	Q9NVI7	1
+Cyclic nucleotide-binding domain [IPR000595]	0.642772289590464	0.9522303235942928	0.3409801854796772	1.0	0.8353948073408916	4	P10644	1
+Peptidase M28 [IPR007484]	0.6490920432608425	0.9080548880599988	0.3638492230545671	1.0	0.8478106526317781	3	Q969V3	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.8470295268587702	0.900087200481633	0.3680738469905997	1.0	0.8492408106631661	2	Q15118	1
+Histidine kinase domain [IPR005467]	0.8470295268587702	0.900087200481633	0.3680738469905997	1.0	0.8492408106631661	2	Q15118	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8452508004268978	0.8935572197131255	0.3715588442560908	1.0	0.8507033837146916	2	Q8N2A8	1
+SUN coiled coil domain 2 [IPR040994]	0.8420490928495232	0.8818272333755796	0.3778702421311908	1.0	0.8566299774816454	2	O94901	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.6184307271824935	0.8524230850127889	0.3939793119093742	1.0	0.8608156447494201	4	P07196,Q16352	2
+Peptidase M16, N-terminal [IPR011765]	0.5282438659924261	0.8522778588386859	0.394059891897482	1.0	0.8608156447494201	7	P22695,Q10713	2
+Peptidase M16, C-terminal [IPR007863]	0.5282438659924261	0.8522778588386859	0.394059891897482	1.0	0.8608156447494201	7	P22695,Q10713	2
+CBS domain [IPR000644]	0.526012081128169	0.8412900615759675	0.4001854569373178	1.0	0.862197318738547	7	P51790,P51798	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.5258561480916459	0.8296195456263027	0.4067539223213301	1.0	0.870873030792127	6	Q92604,Q8NF37,Q6UWP7	3
+BRICHOS domain [IPR007084]	0.8231945926716522	0.813426584408632	0.4159735225488208	1.0	0.871761020040237	2	Q9Y287	1
+ELMO domain [IPR006816]	0.8196371398078994	0.8006611981492061	0.4233278114583563	1.0	0.8759687897173362	2	Q8IZ81	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.6185535734667076	0.7839830458430979	0.433050058593551	1.0	0.8818125529413814	3	O00203	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5047076797653964	0.7480289598307971	0.4544426898062599	1.0	0.8914515168322286	8	P08183,Q03518,O75027	3
+FAD linked oxidase, N-terminal [IPR006094]	0.7965136961935316	0.7189305930224879	0.4721836855591648	1.0	0.9040852515062104	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.7965136961935316	0.7189305930224879	0.4721836855591648	1.0	0.9040852515062104	2	Q15392	1
+Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]	0.7940234791889079	0.710268557311645	0.4775376141452463	1.0	0.9040852515062104	2	Q9NZ45	1
+Iron-binding zinc finger, CDGSH type [IPR018967]	0.7940234791889079	0.710268557311645	0.4775376141452463	1.0	0.9040852515062104	2	Q9NZ45	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.7936677339025294	0.7090335030008647	0.4783036864423591	1.0	0.9040852515062104	2	Q06481	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.7922447527570297	0.7040993024708591	0.4813709344906729	1.0	0.9052334211977088	2	P23634	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.4965318879778665	0.6461382033976109	0.5181898559592133	1.0	0.9288039054232016	5	Q8N4Q0	1
+HDGF-related, PWWP domain [IPR035496]	0.5602170728314786	0.6203096946131637	0.5350539135160055	1.0	0.9365390412109114	4	Q9Y3E1,Q7Z4V5	2
+Legume-like lectin [IPR005052]	0.7655638562789082	0.6135044208483266	0.5395428605397721	1.0	0.9391042401806112	2	Q12907	1
+Zinc finger, CHHC-type [IPR012996]	0.5727341380632379	0.6050852205821741	0.545122373807277	1.0	0.941670258152226	3	P31943	1
+Fatty acid desaturase domain [IPR005804]	0.7623621487015353	0.6028982382643058	0.5465763880472496	1.0	0.941670258152226	2	O15121	1
+Chromo shadow domain [IPR008251]	0.5711743772241973	0.599198328360016	0.5490406373848264	1.0	0.941670258152226	3	P83916,P45973	2
+Chromo domain subgroup [IPR017984]	0.5711743772241973	0.599198328360016	0.5490406373848264	1.0	0.941670258152226	3	P83916,P45973	2
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.4750534568781127	0.5940159407045504	0.5525014512326867	1.0	0.9419110219259746	7	Q7L5N1,P51665,O00303,Q92905,O15372,O00487	6
+Fzo/mitofusin HR2 domain [IPR006884]	0.7577374599786603	0.5876871233453608	0.5567423201527715	1.0	0.9440413254764386	2	Q8IWA4	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.5629893238434114	0.5685683405014519	0.5696491151558014	1.0	0.9531941684824584	3	Q06203,Q06210	2
+Tim44-like domain [IPR007379]	0.7488438278192859	0.5588110488295861	0.5762906811241706	1.0	0.9554057879306402	2	O43615	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.7445748843827866	0.545133463737753	0.5856617288755377	1.0	0.9600013750038532	2	Q15067	1
+EF hand associated, type-2 [IPR013567]	0.7371042333689128	0.5214963406351015	0.6020210541111992	1.0	0.9614718366302624	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.7371042333689128	0.5214963406351015	0.6020210541111992	1.0	0.9614718366302624	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.7371042333689128	0.5214963406351015	0.6020210541111992	1.0	0.9614718366302624	2	Q8IXI1	1
+Importin-beta, N-terminal domain [IPR001494]	0.4417558702815485	0.4989329690620784	0.6178266069595197	1.0	0.9730451900163276	13	Q96P70,O15397,Q8TEX9,O43592,Q14974,P55060	6
+Choline/carnitine acyltransferase domain [IPR039551]	0.7296335823550392	0.4982550359569841	0.6183042956577114	1.0	0.9730542852839952	2	P23786	1
+Armadillo repeat-containing domain [IPR006911]	0.7271433653504145	0.4905990809713359	0.6237100365583206	1.0	0.9734525138820824	2	Q8N2F6	1
+Tudor domain [IPR002999]	0.4491562826963265	0.4784613646431273	0.6323218665476449	1.0	0.973985896243036	8	Q14739,Q9Y2W6	2
+RNA-binding S4 domain [IPR002942]	0.5348754448398512	0.4671290415046348	0.6404075573972399	1.0	0.977892297099392	3	P46781,P62701	2
+CNNM, transmembrane domain [IPR002550]	0.7157595161864162	0.4562057328640055	0.6482420433195879	1.0	0.9793860418111436	2	Q6P4Q7	1
+Ion transporter-like, CBS domain [IPR044751]	0.7157595161864162	0.4562057328640055	0.6482420433195879	1.0	0.9793860418111436	2	Q6P4Q7	1
+GYF domain [IPR003169]	0.7090003557452923	0.4362733778132021	0.6626383949101069	1.0	0.9829004979433206	2	O95400	1
+Acyltransferase, C-terminal domain [IPR032098]	0.5253616746065973	0.43430581866159	0.6640663790604515	1.0	0.9829004979433206	3	Q92604	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5005339978640057	0.4001533660241337	0.6890435599901257	1.0	0.9860557695363305	4	Q7L5N1,P51665,O00303	3
+Arf GTPase activating protein [IPR001164]	0.6961935254357946	0.399562353015402	0.6894788896181805	1.0	0.9860557695363305	2	Q15057	1
+CARG-binding factor, N-terminal [IPR012956]	0.6926360725720451	0.3896198303337667	0.6968176862630062	1.0	0.9860557695363305	2	Q14103	1
+CTP synthase GATase domain [IPR033828]	0.6670224119530492	0.3215256274355698	0.7478120945233417	1.0	0.9923375655378904	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.6670224119530492	0.3215256274355698	0.7478120945233417	1.0	0.9923375655378904	2	Q9NRF8	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.6666666666666742	0.3206248724188671	0.7484946864970974	1.0	0.9923375655378904	2	Q14011	1
+Replication factor C, C-terminal [IPR013748]	0.4882562277580081	0.3150506244967987	0.7527232167412596	1.0	0.9923375655378904	3	P35250,P35249	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.4845413290957988	0.3039675911776451	0.7611525820938327	1.0	0.9923375655378904	3	Q32P28	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.6542155816435515	0.2899134582637078	0.7718824453831754	1.0	0.9923375655378904	2	P60903	1
+Intermediate filament, rod domain [IPR039008]	0.4046144178897806	0.2784203378637418	0.7806897091166842	1.0	0.9923375655378904	8	P07196,P48681,Q16352,P08670	4
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.4077635327635289	0.2728548836025272	0.7849647686073475	1.0	0.9923375655378904	5	Q9NVA2,Q16181,Q14141,Q9UHD8	4
+YTH domain [IPR007275]	0.4563901744393024	0.2567234051279906	0.7973923022648604	1.0	0.9923375655378904	4	Q9Y5A9,Q9H6S0,Q7Z739	3
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.6321593738883049	0.2395453606254928	0.8106827273724653	1.0	0.9923375655378904	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.6321593738883049	0.2395453606254928	0.8106827273724653	1.0	0.9923375655378904	2	Q16836	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.3876488096822929	0.2151147074065588	0.8296778874673802	1.0	0.9923375655378904	11	P62942,Q96AY3,Q9NWM8,Q00688,Q13451,Q9Y680	6
+SCP2 sterol-binding domain [IPR003033]	0.4476868327402147	0.2037161059623588	0.8385753553827924	1.0	0.9923375655378904	3	P22307,P51659	2
+Immunoglobulin I-set [IPR013098]	0.6118818925649331	0.1980023608956823	0.8430432165738675	1.0	0.9923375655378904	2	Q8WX93	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6093916755603085	0.1932237416283897	0.846783745957912	1.0	0.9923375655378904	2	Q96AE4	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.60085378868731	0.1773828841647944	0.8592076505900548	1.0	0.9923375655378904	2	O00154	1
+PIH1, N-terminal [IPR012981]	0.5869797225186872	0.1534422944555705	0.87804949362399	1.0	0.9923375655378904	2	Q9NWS0	1
+PIH1D1/2/3, CS-like domain [IPR041442]	0.5869797225186872	0.1534422944555705	0.87804949362399	1.0	0.9923375655378904	2	Q9NWS0	1
+Ras GTPase-activating domain [IPR001936]	0.4177935943060518	0.1365529747039295	0.8913841489461034	1.0	0.9923375655378904	3	P46940,Q14C86	2
+PA domain [IPR003137]	0.569548203486315	0.1265198243071859	0.8993204576105391	1.0	0.9923375655378904	2	Q8TCT8	1
+Heat shock chaperonin-binding [IPR006636]	0.3607549857549865	0.1141177615171085	0.9091444425483546	1.0	0.9923375655378904	5	P54727,Q9BSL1,P31948,Q9NRR5	4
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.5542511561721924	0.1057497891985119	0.9157808757240448	1.0	0.9923375655378904	2	Q7Z4V5	1
+G-protein, beta subunit [IPR001632]	0.5499822127356934	0.1004201098526228	0.9200108051091233	1.0	0.9923375655378904	2	Q13112	1
+Ribosomal protein S7 domain [IPR023798]	0.5478477410174436	0.0978303512329184	0.9220670061787596	1.0	0.9923375655378904	2	P46782	1
+Thioesterase domain [IPR006683]	0.5407328352899448	0.0895547991263339	0.928641005082074	1.0	0.9923375655378904	2	O00154	1
+Ribosomal protein S4/S9, N-terminal [IPR001912]	0.5346851654215695	0.0829455577747507	0.9338948289570256	1.0	0.9923375655378904	2	P46781	1
+DnaJ domain [IPR001623]	0.3488876255064853	0.0779788419520023	0.9378448834116316	1.0	0.9923375655378904	16	Q9NVH1,Q96KC8,Q9UGP8	3
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.520811099252948	0.0692113619917206	0.9448213792349718	1.0	0.9923375655378904	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.520811099252948	0.0692113619917206	0.9448213792349718	1.0	0.9923375655378904	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.520811099252948	0.0692113619917206	0.9448213792349718	1.0	0.9923375655378904	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.520811099252948	0.0692113619917206	0.9448213792349718	1.0	0.9923375655378904	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.520811099252948	0.0692113619917206	0.9448213792349718	1.0	0.9923375655378904	2	A0FGR8	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.519388118107444	0.0679119365350361	0.9458557367110004	1.0	0.9923375655378904	2	P15880	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.519388118107444	0.0679119365350361	0.9458557367110004	1.0	0.9923375655378904	2	P15880	1
+Cyclin-like [IPR013763]	0.5176093916755716	0.0663154928537574	0.9471266488628544	1.0	0.9923375655378904	2	Q00403	1
+Serine aminopeptidase, S33 [IPR022742]	0.5144076840981987	0.0635190263279491	0.9493532090169878	1.0	0.9923375655378904	2	Q8N2K0	1
+Peptidase M20, dimerisation domain [IPR011650]	0.5140519388118238	0.0632143746294717	0.949595798374234	1.0	0.9923375655378904	2	Q8IYS1	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.3690391459074782	0.0560463367441746	0.9553048937636196	1.0	0.9923375655378904	3	Q9UL46,P61289	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.3690391459074782	0.0560463367441746	0.9553048937636196	1.0	0.9923375655378904	3	Q9UL46,P61289	2
+Thioredoxin-like fold [IPR012336]	0.4948416933475733	0.0484917552355732	0.9613243350824454	1.0	0.9932249615864076	2	Q6DKJ4	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.4909284951974514	0.0458897234828129	0.9633981450222396	1.0	0.9932249615864076	2	P24534	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.4909284951974514	0.0458897234828129	0.9633981450222396	1.0	0.9932249615864076	2	P24534	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.483813589469954	0.0414806615730317	0.9669127094127292	1.0	0.9932249615864076	2	O60506	1
+Man1/Src1, C-terminal [IPR018996]	0.4795446460334529	0.0390272975497945	0.9688686248906871	1.0	0.9932249615864076	2	Q8NC56	1
+NLE [IPR012972]	0.4727854855923307	0.0354238883682834	0.9717417365000236	1.0	0.995094675427928	2	Q9NVX2	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.4688722874422065	0.0334888587772017	0.9732847502578108	1.0	0.9960173976372352	2	P51116	1
+Cullin protein, neddylation domain [IPR019559]	0.3296765919131316	0.030991758968274	0.9752761119080344	1.0	0.9973823704446164	5	Q93034,Q13620	2
+Protein kinase, C-terminal [IPR017892]	0.3441281138790116	0.0282973738925428	0.977424975092799	1.0	0.9991358808034344	3	Q16513,P51812	2
+NudC N-terminal domain [IPR025934]	0.44681607968696	0.0244632879761813	0.9804830668961771	1.0	1.0	2	Q9Y266	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.4457488438278315	0.0241007669154618	0.9807722315911518	1.0	1.0	2	P22033	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.4315190323728282	0.0198394297030618	0.9841714637114224	1.0	1.0	2	P13674	1
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.4293845606545841	0.0192860565959803	0.9846129070858198	1.0	1.0	2	O95372	1
+Peptidase S9A, N-terminal domain [IPR023302]	0.4272500889363364	0.0187534409821085	0.9850377959970376	1.0	1.0	2	Q4J6C6	1
+MAGE homology domain [IPR002190]	0.426182853077206	0.0184947442907048	0.9852441702981928	1.0	1.0	2	Q9UNF1	1
+Nuclear transport factor 2 domain [IPR002075]	0.351370594517624	0.0176817688787183	0.9858927247025476	1.0	1.0	4	Q9UN86,Q13283,P61970	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.351370594517624	0.0176817688787183	0.9858927247025476	1.0	1.0	4	Q9UN86,Q13283,P61970	3
+Zinc finger, C3HC4 RING-type [IPR018957]	0.4009249377445844	0.0136810353817398	0.9890844536059704	1.0	1.0	2	O75150	1
+Exportin-1/Importin-beta-like [IPR013598]	0.348166607333576	0.0130041716356099	0.9896244646585756	1.0	1.0	4	O43592,Q9Y5L0,Q9HAV4	3
+Zinc finger, TFIIB-type [IPR013137]	0.3930985414443379	0.0126231287563657	0.9899284679289724	1.0	1.0	2	Q00403	1
+MRG domain [IPR026541]	0.3902525791533383	0.0122805505778415	0.9902017845776848	1.0	1.0	2	Q9UBU8	1
+B-box-type zinc finger [IPR000315]	0.3785129847029652	0.0110771227511271	0.9911619155218558	1.0	1.0	2	Q12899	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.3440056919245921	0.0090079860814612	0.99281276418176	1.0	1.0	2	P51812	1
+PSI domain [IPR016201]	0.2895766631092258	0.0080359743780598	0.9935882891208648	1.0	1.0	2	P05556	1
+AGC-kinase, C-terminal [IPR000961]	0.3442506229975118	0.0074974664125937	0.9940179433482031	1.0	1.0	4	Q16513,P51812,Q96GX5	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "2": "Small GTPase [IPR001806]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:90e5e693a9377582542586dcf9788135db234bb24726bf44d0e7ba03bf9509dc
+size 156694

interpro_family/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Transmembrane emp24 domain-containing protein [IPR015720]	4	5	2.1587641680232843	0.0308684676892991	2.6432038834951457	5.099514563106796	0.3626508447128717	0.2724944971681708	1.287119696753696	0.8431907483703972	1.4713835809049645	0.2794327521776852	0.0002066895764441	1.0	1.0	1.0	0.0003260526470588
+Mitochondrial carrier protein [IPR002067]	10	12	2.0809419597155294	0.0374392188940009	5.686893203883495	11.07766990291262	0.8032246115450145	0.31892620527414	3.2338505495684404	1.5403272908315857	1.3918146051602212	0.3274613788058813	0.0001425043748612	1.0	1.0	0.3842390641974681	2.6826951775292525e-05
+Syntaxin [IPR045242]	4	6	1.973608075389262	0.0484263248015992	2.674757281553398	5.815533980582524	0.7134969984167514	0.3462495636510407	1.4434464182805606	1.4295601388514203	1.142372356309129	0.3001529293380739	0.0024042626838217	1.0	1.0	0.2877500137996227	0.0036942631899424

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2813,
+    "annotations_size": 2237,
+    "title": "Average number of proteins per term",
+    "value": 1.2874385337505587
+}