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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Electron transport chain oxphos system in mitochondria 0.5926890086533942 3.0777691416637443 0.0020855641366794 0.7039282807449416 0.3468266353896685 57 O14949,O96000,O75947,Q9UDW1,P03886,P13073,O75489,P00846,Q7KZN9,P24539,P56385,O75306,O43676,P21912,P31930,O75880,P14406,P03928,P36542,P06576,P20674,O75964,O43674,O14548,O75438,P00403,P14927,Q15526 28
Mitochondrial complex iv assembly 0.8174518384037192 3.052295201708865 0.0022709864021772 0.7343274459988491 0.3468266353896685 13 Q9Y2R0,P20674,P14406,P13073,O43819,Q7KZN9 6
Oxidative phosphorylation 0.537949041508585 2.7839060246171243 0.0053708593016104 0.9567020439381734 0.4851265967018203 34 P06576,O96000,O75947,P03886,O75964,O43674,O75489,P00846,O75438,P24539,Q86Y39,P56385 12
Nonalcoholic fatty liver disease 0.5361661229876974 2.683415475426619 0.0072874393855051 0.9859359503661168 0.4851265967018203 49 O14949,O75306,O43676,O96000,Q9UDW1,P08574,P20674,O43674,P14927,P13073,P14406,O75489,O75438,Q9NX14,Q9P0J0,P00403,Q86Y39 17
Mitochondrial complex i assembly model oxphos system 0.5517289665809167 2.5658131888952487 0.0102934248897215 0.9975997108557912 0.4851265967018203 30 Q9BQ95,O75306,O96000,O43676,P03886,Q8IUX1,O43674,Q9NPL8,Q9NW81,O75489,O75438,Q9NX14,Q9P0J0,Q9Y375 14
Sphingolipid metabolism overview 0.8059019072196599 2.4937593892050844 0.0126398193362493 0.9993984388560933 0.4851265967018203 9 Q16880,Q13510,O95470,Q16739,Q96G23,Q06136 6
Adipogenesis 0.6831590643038669 2.4638150695443897 0.0137467017319417 0.9996871924716236 0.4851265967018203 14 Q9NZ45,P14174 2
Ferroptosis 0.6026498189298651 2.442009569081982 0.0146057594759805 0.9998117905589048 0.4851265967018203 21 Q9NZ45,Q96QD8,P45880,P09601 4
Sphingolipid metabolism integrated pathway 0.7686871139943242 2.419355608057075 0.0155480321247538 0.9998922513507376 0.4851265967018203 10 Q16880,Q13510,O95470,Q16739,Q96G23,O15269,Q06136 7
Mitochondrial complex iii assembly 0.760205057815448 2.376902781636956 0.0174586888771084 0.999965284156525 0.4851265967018203 10 O14949,Q9NVA1,Q9UDW1,P08574,P31930,Q6DKK2,P14927 7
Metabolism of spingolipids in er and golgi apparatus 0.838675213675211 2.2655754170004987 0.0234773916379154 0.9999990344331444 0.4851265967018203 5 Q16880,O95470,Q10472,Q06136 4
Familial partial lipodystrophy fpld 0.8166910706221826 2.2636709234842356 0.0235943621186063 0.9999990995651014 0.4851265967018203 6 O60725,O75844,P20700 3
Sphingolipid pathway 0.7336719351391852 2.2427262959172714 0.0249144698505374 0.999999590832674 0.4851265967018203 10 Q16880,Q13510,O95470,Q16739,Q96G23,O15269,P04062,Q06136 8
Influence of laminopathies on wnt signaling 0.7641546219851637 2.195246558469412 0.0281459161385677 0.9999999409227468 0.4851265967018203 8 O60725,O75844 2
Oxidation by cytochrome p450 0.820755779025909 2.187001562684272 0.028742409918012 0.9999999586980854 0.4851265967018203 5 Q16850,O43169,Q6UW02 3
Ccl18 signaling pathway 0.6997294991751493 2.0680284353687464 0.0386373492970499 0.9999999998944972 0.5215737714214823 10 Q86UE4,P00403,P08670 3
Vitamin d metabolism 0.9215795584178658 2.024327193016033 0.0429364974820134 0.999999999992265 0.5215737714214823 3 P38435 1
Mitochondrial immune response to sarscov2 0.6910400266983792 2.0227559669883974 0.0430983135335285 0.9999999999929912 0.5215737714214823 10 Q9BQ95,P35232,Q7Z434,Q86UT6,Q99623,O94826,Q9Y375 7
Degradation pathway of sphingolipids including diseases 0.762379764873525 2.0171292210656535 0.043682029925234 0.9999999999950892 0.5215737714214823 6 O43681,P06865,P17900,P16278,P06280 5
Glycosaminoglycan degradation 0.7623797648735248 2.0171292210656513 0.0436820299252342 0.9999999999950892 0.5215737714214823 6 P08236,P15586,P06865,P16278,P54802 5
Overlap between signal transduction pathways contributing to lmna laminopathies 0.6407492205075836 1.964178920560188 0.0495093464609557 0.9999999999998608 0.5305868940797362 12 P55209,P50402,P42167,O60725,O75844 5
Sphingolipid metabolism in senescence 0.6262121347910237 1.8816876456479203 0.0598784381361552 0.9999999999999998 0.5621593585703989 12 Q13510,Q16739,Q96G23,O15269,P04062,Q06136 6
Metapathway biotransformation phase i and ii 0.5272013770499104 1.8763680509566472 0.0606047585054809 1.0 0.5621593585703989 20 Q7LGA3,Q6UW02,Q16850,P34913,Q8NCH0,P21964 6
Omega3 omega6 fatty acid synthesis 0.7306733167082236 1.8700279711877332 0.0614799336961318 1.0 0.5621593585703989 6 Q15067,O95573,O15254,P33121,O95864 5
Omega9 fatty acid synthesis 0.7063166177197305 1.7554918964141553 0.079175205564268 1.0 0.5774009511650637 6 O95573,P33121,O00767,O95864 4
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8546337979659189 1.7537814887402776 0.0794679561391293 1.0 0.5774009511650637 3 P09601 1
Acquired partial lipodystrophy barraquersimons syndrome 0.8251384454130587 1.7417475694071114 0.0815526247314251 1.0 0.5774009511650637 4 O60725,P20700 2
Cellular proteostasis 0.7977368236513281 1.630471756302893 0.103001829773953 1.0 0.5774009511650637 4 P61758,O15212 2
S1p receptor signal transduction 0.667656051944234 1.5711320109850415 0.1161519884622863 1.0 0.5774009511650637 6 Q13510,P63096 2
Pathways of nucleic acid metabolism and innate immune sensing 0.6815259582022148 1.5538904319096043 0.1202105544136913 1.0 0.5774009511650637 5 Q7Z434 1
Camkk2 pathway 0.6007180589993144 1.539601363442708 0.1236575529369499 1.0 0.5774009511650637 10 Q9Y3D6,P09601 2
Proteoglycan biosynthesis 0.774909574611707 1.537109595660545 0.1242664735484262 1.0 0.5774009511650637 4 Q8NCH0 1
Cholesterol metabolism with bloch and kandutschrussell pathways 0.4700895965711961 1.4863472581128967 0.137187292657974 1.0 0.5774009511650637 21 O95573,O00767,P35610,Q14739,Q16850,P14324,P33121,Q15392,Q14534,O95864,Q15800 11
Intracellular trafficking proteins involved in cmt neuropathy 0.5830654082193598 1.442775718567028 0.1490836613290467 1.0 0.5792061677018835 10 Q15907,Q9NR77 2
Progeriaassociated lipodystrophy 0.590200530826894 1.3990352203945258 0.1618024216337916 1.0 0.6046846911057727 9 O60725,O75844,P20700 3
Mecp2 and associated rett syndrome 0.4658965801799616 1.3834494529807988 0.1665270960371734 1.0 0.6130357225496249 18 P31943,P67809,P35637 3
Novel intracellular components of rigilike receptor rlr pathway 0.5824804224363136 1.3577918511299203 0.1745297413889186 1.0 0.6273838315977907 9 Q86UT6 1
Vitamin b12 disorders 0.7569991470196222 1.3511334013598764 0.1766527035862022 1.0 0.6279788182363164 3 Q96EY8 1
Vitamin d receptor pathway 0.558587985641637 1.3075299770599236 0.1910327808336709 1.0 0.6623546277337217 10 Q92604,Q5VV42,Q96KA5,P04080 4
Cholesterol biosynthesis with skeletal dysplasias 0.6276086295016754 1.299855296562236 0.1936505690849201 1.0 0.6623546277337217 5 Q16850,Q15392 2
Inclusion body myositis 0.7409252669039161 1.2844167584539607 0.1989961723237079 1.0 0.662941534084124 3 Q92542,P05067 2
Statin inhibition of cholesterol production 0.7103993727800144 1.2709238220481929 0.2037557506569423 1.0 0.6673573181629066 4 Q8WTV0,Q14534 2
Zinc homeostasis 0.7256227758007123 1.220932305027038 0.2221116517868 1.0 0.6961886719984108 3 Q8NEW0,Q8TAD4 2
Nanomaterial induced apoptosis 0.6083273397616744 1.208362284004024 0.2269079405616474 1.0 0.7074188735157244 5 Q9NR28 1
Arachidonate epoxygenase epoxide hydrolase 0.9302739238705088 1.2046777233292196 0.2283277390389801 1.0 0.70805889287088 2 P34913 1
Prostaglandin and leukotriene metabolism in senescence 0.9210245464247616 1.1695546270651522 0.2421802456735253 1.0 0.7095029307922879 2 P09960 1
Purinergic signaling 0.7005349041754619 1.1170990170528152 0.2639519907484833 1.0 0.7206858211576037 3 P63096 1
Endothelin pathways 0.546818474671876 1.097895960796332 0.272249921946456 1.0 0.7206858211576037 8 P42892,P00403,P63096 3
Mitochondrial long chain fatty acid betaoxidation 0.4758198156477538 1.083971104468228 0.2783776108536497 1.0 0.7264857565648328 13 O95573,Q16836,P23786,P33121,P49748,P22307 6
Copper homeostasis 0.5427233561625122 1.0765180745666765 0.2816956218138586 1.0 0.7264857565648328 8 O75880,O43819 2
Cytosolic dnasensing pathway 0.5105657071616607 1.0402106326477574 0.2982420527139129 1.0 0.7398941137540904 10 Q86UT6 1
Eicosanoid synthesis 0.8815368196371427 1.0209456354941426 0.3072801962521541 1.0 0.7402659273347348 2 P09960 1
Kennedy pathway from sphingolipids 0.6471864251493269 1.00943978601099 0.3127637657273017 1.0 0.7457459678686412 4 Q9UG56,O95470 2
7oxoc and 7betahc pathways 0.5247617080427913 0.9828097678231512 0.3257010735351833 1.0 0.7565088680119995 8 P22307,O15118,P34913,O14734 4
Vitamin b12 metabolism 0.5356550249382036 0.9799329908901336 0.3271191967099871 1.0 0.7567876654044544 7 Q8WTV0,Q96EY8 2
Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.5183725077442303 0.9495311549086716 0.3423505343530424 1.0 0.7862204158345257 8 P31943,P61020,P20339 3
Nephrotic syndrome 0.4600948874900641 0.9017442037582072 0.367192765544071 1.0 0.798017155494767 12 Q14108,O75844,Q96D53 3
Nocgmppkg mediated neuroprotection 0.6191122526161769 0.8944462888642751 0.3710831553460612 1.0 0.798017155494767 4 P07196 1
G protein signaling pathways 0.4575315152224441 0.8864643774729618 0.3753673417055756 1.0 0.798017155494767 12 P63096,P04899,O43823 3
Mrna protein and metabolite inducation pathway by cyclosporin a 0.6427046263345214 0.8808468748998958 0.3784007047190805 1.0 0.798017155494767 3 P08195,Q9UPY5 2
Caloric restriction and aging 0.6362989323843403 0.8551286765701287 0.3924799156758651 1.0 0.8031076688930883 3 P43490,P42345 2
Interactions between loxl4 and oxidative stress pathway 0.8363571682675219 0.8549121137702741 0.3925998038328133 1.0 0.8031076688930883 2 Q9BQ95 1
Oxysterols derived from cholesterol 0.5048972950389474 0.8251611373425193 0.4092801137712993 1.0 0.8192401694336006 7 P22307,P34913,O14734 3
Glycerolipids and glycerophospholipids 0.6003348096337978 0.8183924674884269 0.4131331214639426 1.0 0.8192401694336006 4 Q9UG56 1
Spinal cord injury 0.3823703988233018 0.7758539068208959 0.4378352506941407 1.0 0.8341763109630197 18 P14174,P08670 2
Type i collagen synthesis in the context of osteogenesis imperfecta 0.4185193573668236 0.7293126604026728 0.4658104296324103 1.0 0.8544833170121137 13 O75718,Q32P28,P13674 3
Eicosanoid metabolism via lipooxygenases lox 0.4832762830519397 0.6731393332742179 0.5008586524504852 1.0 0.8590068512994572 6 P09960 1
Regulation of apoptosis by parathyroid hormonerelated protein 0.5622696824239994 0.6675236352611104 0.5044377177151866 1.0 0.8590068512994572 4 Q9BXK5 1
Heme biosynthesis 0.4886385628043465 0.6478051643619014 0.5171109747498814 1.0 0.8738426037077707 5 P36551 1
Sarscov2 and covid19 pathway 0.5811155913038084 0.6399693876593189 0.5221925014142201 1.0 0.8772750394882631 3 Q8WTV0 1
Sarscov2 b117 variant antagonises innate immune activation 0.7741017431519075 0.6377192446412804 0.523656455818037 1.0 0.8772750394882631 2 Q7Z434 1
Preimplantation embryo 0.446150352800808 0.5379778579204019 0.5905923351282072 1.0 0.9161740801123068 7 Q99729 1
Tgfbeta receptor signaling 0.525453898184411 0.527897376283342 0.5975705658542636 1.0 0.9161740801123068 4 P35222,P62942,P42224 3
Tgfbeta receptor signaling in skeletal dysplasias 0.525453898184411 0.527897376283342 0.5975705658542636 1.0 0.9161740801123068 4 P35222,P62942,P42224 3
Fatty acid betaoxidation 0.3461191473603725 0.5265591227195923 0.5984997849135647 1.0 0.9161740801123068 19 O95573,Q16836,P35610,P23786,P33121,P49748 6
Calcium regulation in cardiac cells 0.3332755432756975 0.5129791361238206 0.60796591525099 1.0 0.9175063883800608 25 P16615,P04899,Q9Y3B8,P63096 4
Cholesterol biosynthesis pathway 0.4091665910077228 0.489135954282876 0.6247454483359958 1.0 0.9283046707767812 10 Q16850 1
Ppar signaling pathway 0.3427516379022849 0.489091098760897 0.6247772029909826 1.0 0.9283046707767812 16 Q15067,Q13418,O95573,O00767,O15254,P23786,P33121,O95864,P22307 9
Ketogenesis and ketolysis 0.4421291441861054 0.4824951320437007 0.6294542556867047 1.0 0.9283046707767812 6 P23786,P53985 2
Mitochondrial gene expression 0.4953675821587704 0.420435628284414 0.6741672453149019 1.0 0.9599257418200712 4 O00411,Q9P2K5 2
Glycerophospholipid biosynthetic pathway 0.4121916879981243 0.3823902753009422 0.7021719025062882 1.0 0.9657544893450384 7 O95674,Q9BTU6,O00116 3
Autosomal recessive osteopetrosis pathways 0.6844539309854214 0.365052416273718 0.7150722796011177 1.0 0.9657544893450384 2 P51798 1
Amyotrophic lateral sclerosis als 0.3657946643376134 0.3639498931204539 0.7158954264906439 1.0 0.9657544893450384 12 P07196,Q9BUN8,P20339 3
Tryptophan metabolism 0.3316044778095918 0.3459218598156259 0.7294014399185564 1.0 0.9657544893450384 15 Q15392,Q16836 2
Apoptosis modulation and signaling 0.3409378997720158 0.3380714658727927 0.7353093328122438 1.0 0.9657544893450384 14 O95831,Q9NR28 2
Mitochondrial complex ii assembly 0.6641764496620499 0.312620696790754 0.7545688519797322 1.0 0.9754169353037294 2 P21912 1
Fluoropyrimidine activity 0.3545319851358796 0.3060504769999088 0.7595662133829855 1.0 0.9762923869425896 12 P00374,Q99808,P31350 3
Amino acid metabolism pathway excerpt histidine catabolism extension 0.6606189967983003 0.3038394675461052 0.7612501965538467 1.0 0.9762923869425896 2 P00367 1
Ciliopathies 0.3338690409127413 0.298902462158702 0.7650144684131677 1.0 0.9762923869425896 14 Q10713,Q15555 2
Joubert syndrome 0.3225108361552091 0.2931393282054146 0.7694156569012811 1.0 0.9782454406445033 15 O43924,Q13432,P41208,Q15382,Q10713 5
Myometrial relaxation and contraction pathways 0.297912873752775 0.2106466646102032 0.8331629961152323 1.0 0.9888462089170892 17 P16615,Q9Y3B8 2
Apoptosis 0.3575046137955772 0.2093084242325924 0.8342074758410758 1.0 0.9888462089170892 9 Q9NR28 1
Genes related to primary cilium development based on crispr 0.3306073258839574 0.1909679848025066 0.8485506759461143 1.0 0.9888462089170892 12 Q96J42,Q10713 2
Initiation of transcription and translation elongation at the hiv1 ltr 0.3639708272488128 0.1851793991338405 0.8530883267503784 1.0 0.9888462089170892 7 Q8IXH7 1
Il18 signaling pathway 0.2818187812099215 0.1710101587112644 0.8642157777672765 1.0 0.9888462089170892 53 Q9UMR5,Q16836,Q9HC07,P09601 4
Pkcgamma calcium signaling pathway in ataxia 0.5962290999644355 0.1683870129331139 0.8662788244040267 1.0 0.9888462089170892 2 P23634 1
Immune response to tuberculosis 0.555318392031316 0.1066256724995082 0.9150859509765752 1.0 1.0 2 Q03518 1
Biomarkers for pyrimidine metabolism disorders 0.3456845690212941 0.1050878042512257 0.9163061365157648 1.0 1.0 6 P31350 1
Aryl hydrocarbon receptor pathway wp2873 0.3236174293660049 0.0406600541039012 0.9675669074495408 1.0 1.0 6 Q15185 1
Cardiac progenitor differentiation 0.4692280327285789 0.0331968586194762 0.9735176032019124 1.0 1.0 2 Q6ZN17 1
Serotonin htr1 group and fos pathway 0.3066924567524268 0.027725288462714 0.9778812541771864 1.0 1.0 9 P63096 1
Steroid biosynthesis 0.4553539665599551 0.0271010075188504 0.9783791711731616 1.0 1.0 2 P51659 1
Oligodendrocyte specification and differentiation leading to myelin components for cns 0.4475275702597057 0.0241901139103172 0.9807009637811028 1.0 1.0 2 P09543 1
Pilocytic astrocytoma 0.4098185699039605 0.0144937838901339 0.9884360384809918 1.0 1.0 2 P62993 1
Mammary gland development pathway involution stage 4 of 4 0.3980789754535902 0.0126299458876824 0.9899230290787197 1.0 1.0 2 P04637 1
Tp53 network 0.3980789754535902 0.0126299458876824 0.9899230290787197 1.0 1.0 2 P04637 1
Envelope proteins and their potential roles in edmd physiopathology 0.2571745034389793 0.0060817582390413 0.9951474889124898 1.0 1.0 17 P50402,O94901,P42166,P42167 4