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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ce88fd256ba0b13cf80d9e90998d2c9249b5200a79e27b7bc2204231052f5b8c
+size 68810

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.327272727272727
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C237/C237_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9809523809523816	1.9561056560909156	0.0504527090071627	0.9420020090025556	0.2774898995393948	3	Q9HB40,Q9H3G5	2
+Cysteine peptidase, cysteine active site [IPR000169]	0.8749302512827557	1.5665510853835438	0.1172196588823728	0.9989482901910488	0.4278011739498909	3	P53634	1
+Tyrosine-protein kinase, active site [IPR008266]	0.6978245931328605	1.2572832946992871	0.2086510708861824	0.9999974281771862	0.4740915555489434	5	P07947,Q15375	2
+Nucleoside diphosphate kinase, active site [IPR023005]	0.6439986399183999	0.2635898483243453	0.7920959818241637	1.0	0.947071282615848	2	P22392	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.2452971955026267	0.0462445037568757	0.963115371527794	1.0	0.9994593478118616	5	Q13614	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.2145315459649525	0.0093151513817528	0.9925676920172076	1.0	1.0	6	P60604	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K2", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE2T", "UMPS", "VRK1", "YES1"], "leading_proteins": ["CPVL", "CTSC", "EPHA7", "MTMR2", "NME2", "SCPEP1", "UBE2G2", "YES1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:414aadb773ad08de18158f86b4d0ac4588f777441e401e157a548fcc0c1bc0b1
+size 66586

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.0625
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C237/C237_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+IQ motif, EF-hand binding site [IPR000048]	0.3852336206100753	0.3226619235082494	0.7469512915946248	1.0	1.0	9	Q92614,Q13576,P35579	3
+Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]	0.5800748044882783	0.1660780370736629	0.8680955379922541	1.0	1.0	2	P17174	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["GOT1", "IQGAP2", "MYH9", "MYO18A"]}

interpro_conserved_site/advanced/idx2term.json

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+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Thioredoxin, conserved site [IPR017937]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:cd31c82e153ceb13bd699d9609b9a42fa15eaaab40bc321f465b713a6e23283c
+size 78103

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 271,
+    "title": "Average number of proteins per term",
+    "value": 2.623616236162362
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C237/C237_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EGF-like calcium-binding, conserved site [IPR018097]	0.9765226267437892	2.2390475086252164	0.0251528251218755	0.9989958429441634	0.4285052329621669	4	P01130,P98164,Q07954	3
+Cadherin conserved site [IPR020894]	0.9407961891799896	2.108217035562364	0.0350122203848037	0.9999361131495912	0.4285052329621669	4	Q02487,P19022,Q14574	3
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.9328321186001856	2.0788242247206137	0.0376335094651856	0.9999694315460854	0.4285052329621669	4	O75874	1
+Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]	0.9806122448979602	1.954870105212204	0.0505984038922115	0.9999992256478932	0.4285052329621669	3	P01130,Q07954	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.9591836734693916	1.8768156937049796	0.0605433587643955	0.9999999553730936	0.4501000719255999	3	P55899,P04439	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7473781803371524	1.8410616611413528	0.0656125231666644	0.9999999897004208	0.4501000719255999	8	P28070,P28072,P20618,P49720,P49721	5
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8052397921303814	1.760056792025515	0.078398177813646	0.9999999997538268	0.4794469473351533	6	O60499,Q86Y82,Q13277	3
+Guanylate kinase, conserved site [IPR020590]	0.7359233835942816	1.4882360830376713	0.1366886445000972	1.0	0.5647729141774398	6	Q9NZW5,Q5T2T1	2
+Chromo domain, conserved site [IPR023779]	0.7248955196233309	1.3633173487351715	0.1727825167157408	1.0	0.5973006152427466	5	P83916,P45973	2
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.5973006152427466	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.5973006152427466	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.5973006152427466	2	P05067	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.9819789187351244	1.284971305887378	0.1988023112818449	1.0	0.6338285453809407	2	P04066	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.9789187351241078	1.273908791205398	0.2026957424370727	1.0	0.6387272814005434	2	P11279	1
+C-type lectin, conserved site [IPR018378]	0.9710982658959546	1.2456783388419796	0.2128825091194199	1.0	0.6631167812800324	2	Q5KU26	1
+Sterol reductase, conserved site [IPR018083]	0.9364161849711006	1.1213591123248756	0.2621350330409355	1.0	0.7206015232833091	2	Q9UBM7	1
+Sugar transporter, conserved site [IPR005829]	0.9221353281196912	1.0706992014052783	0.2843047019919467	1.0	0.7408324446136303	2	Q7L0J3	1
+Tetraspanin, conserved site [IPR018503]	0.9098945936756252	1.027586175670185	0.3041445298281631	1.0	0.7703099774152542	2	O43657	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.680952380952374	0.8571148718095711	0.3913814029187323	1.0	0.8802128102371164	3	O00469,Q02809	2
+Calreticulin/calnexin, conserved site [IPR018124]	0.6703177576903475	0.8201792438587394	0.412113932647608	1.0	0.8802128102371164	3	P27824	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]	0.4397020553190662	0.5336549001674008	0.593580317385439	1.0	0.992641052048679	9	Q9UNP9	1
+Thioredoxin, conserved site [IPR017937]	0.4065208707190343	0.488297969314095	0.6253387996472439	1.0	0.992641052048679	13	Q96JJ7,P13667,Q9H3N1,Q9H1E5,Q14554,Q8IXB1,O95881	7
+Serpin, conserved site [IPR023795]	0.7126827609656584	0.4137988164474143	0.6790214508309222	1.0	0.992641052048679	2	P35237	1
+Kinesin motor domain, conserved site [IPR019821]	0.4093496266424397	0.4124409169128822	0.6800162778744365	1.0	0.992641052048679	9	Q9NQT8,O00139	2
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4931972789115662	0.3055889406163252	0.7599176420249787	1.0	0.992641052048679	3	P14625,P07900	2
+Clathrin adaptor complex, small chain [IPR000804]	0.6558993539612415	0.2863529595551778	0.7746077996113938	1.0	0.992641052048679	2	P61923	1
+Ribosomal S11, conserved site [IPR018102]	0.6167970078204759	0.2169820399302263	0.8282223415757064	1.0	0.992641052048679	2	P82912	1
+Ribosomal protein S2, conserved site [IPR018130]	0.5205712342740701	0.1110143314839105	0.9116049821000672	1.0	0.992641052048679	2	P08865	1
+Vinculin, conserved site [IPR000633]	0.5110506630397845	0.1049749389087492	0.9163956946806286	1.0	0.992641052048679	2	P18206	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.5100306018361237	0.1043677577779055	0.9168775084826196	1.0	0.992641052048679	2	P14174	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.4841890513430925	0.0913525319060434	0.9272124780225156	1.0	0.992641052048679	2	Q13576	1
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.4127847670860261	0.0732858453404725	0.941578655192391	1.0	0.992641052048679	2	Q16762	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRM", "STAM", "STMN1", "STOM", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["APP", "CANX", "CBX1", "CBX5", "CDH2", "COLEC12", "COPZ1", "DHCR7", "DNAJC10", "DSC2", "DSC3", "FCGRT", "FUCA1", "HLA-A", "HSP90AA1", "HSP90B1", "IDH1", "IQGAP2", "KIF13B", "KIF2A", "LAMP1", "LDLR", "LRP1", "LRP2", "MIF", "MPP6", "MPP7", "MRPS11", "PDIA4", "PDIA5", "PLOD1", "PLOD2", "PPIE", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB6", "RPSA", "SERPINB6", "STX10", "STX12", "STX3", "SV2A", "TMX1", "TMX3", "TMX4", "TSPAN6", "TST", "TXNDC12", "VCL"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Immunoglobulin-like domain [IPR007110]", "1": "Target SNARE coiled-coil homology domain [IPR000727]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Immunoglobulin-like domain [IPR007110]", "1": "Target SNARE coiled-coil homology domain [IPR000727]", "2": "TGS [IPR004095]", "3": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "4": "S1 domain [IPR003029]", "5": "Aminotransferase, class I/classII [IPR004839]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:eac424c9edba177c2d22a2e1e15104f9feffad96e8876f10dd5c5c12e1c6f362
+size 186786

interpro_domain/df_merge.tsv

@@ -0,0 +1,7 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Immunoglobulin-like domain [IPR007110]	9	11	2.8116238709723573	0.0049292106793219	4.480582524271845	12.427184466019416	0.4075261998509777	0.4433674298264088	2.6479725987944898	3.173316973839475	1.1756568118942026	0.3233613924696422	0.1978375242949675	0.0920007636937663	0.0038387330014102	0.0003552000776165	0.0200261755710175
+Fibronectin type III [IPR003961]	2	6	2.27786382045119	0.0227346924506794	2.2257281553398056	5.589805825242719	-0.3209057323720775	0.5133796044193292	1.3812257831232946	2.0501463270450144	0.914078257814304	0.3019356379166223	0.0147423963853305	0.0039642726692088	0.0276366046790147	0.2393919214191436	0.6715643009910249
+Immunoglobulin subtype [IPR003599]	4	6	2.216180204698883	0.0266791630271228	2.9684466019417477	8.483009708737864	0.1381371967634491	0.4928258967784709	2.271921156707309	2.9216637549507847	1.0756254869730633	0.312999744433737	0.5083206499759158	0.3564113417306869	0.0602097240353476	0.0817694862510833	0.3247656096882634
+Immunoglobulin subtype 2 [IPR003598]	4	6	2.216180204698883	0.0266791630271228	2.8106796116504853	8.04126213592233	0.1764352420775828	0.5005828106358552	2.0581551085254395	2.677802743524345	1.0491539805619012	0.3137632145774063	0.3916270572121257	0.2654506957294806	0.0247132014905158	0.022785720496239	0.108286865943572
+Target SNARE coiled-coil homology domain [IPR000727]	6	10	2.1886346693431333	0.0286234038576445	3.5024271844660193	8.266990291262136	0.5942034778060385	0.4012381903331891	1.9023475359698396	2.183694577914796	1.0582363712887182	0.3038263160802639	1.0	1.0	1.0	0.1187178452167528	0.0009781828033221
+Band 7 domain [IPR001107]	2	8	1.9921487706278136	0.0463547371853436	3.825242718446602	7.354368932038835	0.2848798017769268	0.3662852929750465	1.8717479731706237	0.7075565364256523	1.25010454777189	0.3076860385713043	1.0	1.0	1.0	0.0182345355868198	0.0074990795763075

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 2490,
+    "title": "Average number of proteins per term",
+    "value": 2.1244979919678717
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C237/C237_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,204 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Immunoglobulin-like domain [IPR007110]	0.9375741428049644	2.8116238709723573	0.0049292106793219	0.9999954668082124	0.4151448988483877	11	P55899,P35613,Q13740,P04439,Q92859,Q9Y624,P10321,P43121,P01889	9
+Fibronectin type III [IPR003961]	0.9421175615073676	2.27786382045119	0.0227346924506794	1.0	0.4151448988483877	6	Q15375,Q92859	2
+EGF-like calcium-binding domain [IPR001881]	0.9765226267437892	2.2390475086252164	0.0251528251218755	1.0	0.4151448988483877	4	P01130,P98164,Q07954	3
+EGF-like domain [IPR000742]	0.9765226267437892	2.2390475086252164	0.0251528251218755	1.0	0.4151448988483877	4	P01130,P98164,Q07954	3
+Immunoglobulin subtype [IPR003599]	0.9254116743465248	2.216180204698883	0.0266791630271228	1.0	0.4151448988483877	6	P43121,Q9Y624,P35613,Q92859	4
+Immunoglobulin subtype 2 [IPR003598]	0.9254116743465248	2.216180204698883	0.0266791630271228	1.0	0.4151448988483877	6	P43121,Q9Y624,P35613,Q92859	4
+Target SNARE coiled-coil homology domain [IPR000727]	0.8031461316550755	2.1886346693431333	0.0286234038576445	1.0	0.4151448988483877	10	O15400,Q5SQN1,O60499,Q86Y82,Q13277,Q9UNK0	6
+MHC class I-like antigen recognition-like [IPR011161]	0.9595100374276972	2.176958430550536	0.0294836691545281	1.0	0.4151448988483877	4	P55899,P10321,P04439	3
+Immunoglobulin C1-set [IPR003597]	0.9595100374276972	2.176958430550536	0.0294836691545281	1.0	0.4151448988483877	4	P55899,P10321,P04439	3
+Cadherin-like [IPR002126]	0.9407961891799896	2.108217035562364	0.0350122203848037	1.0	0.4151448988483877	4	Q02487,P19022,Q14574	3
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.9328321186001856	2.0788242247206137	0.0376335094651856	1.0	0.4236492329969705	4	O75874	1
+Band 7 domain [IPR001107]	0.7834372627612237	1.9921487706278136	0.0463547371853436	1.0	0.4236492329969705	8	P27105,O75955	2
+Cadherin prodomain [IPR014868]	0.9690476190476198	1.9127971712309892	0.0557740234451544	1.0	0.4335120613231118	3	Q02487,Q14574	2
+Cadherin, cytoplasmic domain [IPR000233]	0.9690476190476198	1.9127971712309892	0.0557740234451544	1.0	0.4335120613231118	3	Q02487,Q14574	2
+Ricin B, lectin domain [IPR000772]	0.8612784537699705	1.890542798569927	0.0586854022441634	1.0	0.4342143932667177	5	Q10472,Q86SF2,Q9UBG0	3
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.9591836734693876	1.8768156937049667	0.0605433587643973	1.0	0.4382353584981084	3	P10321,P04439	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.9591836734693876	1.8768156937049667	0.0605433587643973	1.0	0.4382353584981084	3	P10321,P04439	2
+Immunoglobulin V-set domain [IPR013106]	0.9547619047619064	1.8606585225820187	0.0627924147105245	1.0	0.4420033808899081	3	P43121,Q9Y624	2
+Fibronectin type II domain [IPR000562]	0.9536608647884236	1.8566327291689384	0.0633634241924241	1.0	0.4420033808899081	3	P11717	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.805582749434717	1.7613876929059469	0.0781728066317146	1.0	0.4580006788540459	6	O43169,Q8WUJ1	2
+Peptidase M28 [IPR007484]	0.9192537083064268	1.7303463633132894	0.0835684106782488	1.0	0.4685880164679802	3	P02786	1
+MRH domain [IPR044865]	0.9102506459235638	1.6971630431270086	0.0896658400164835	1.0	0.4773555977373259	3	P11717	1
+PWWP domain [IPR000313]	0.7494286558620845	1.690852289953786	0.0908650173832121	1.0	0.4774341543719861	7	P51858,Q7Z4V5	2
+Syntaxin, N-terminal domain [IPR006011]	0.9003401360544202	1.660578232660168	0.0967981837033291	1.0	0.4793277390584726	3	Q86Y82,Q13277	2
+Homeobox domain [IPR001356]	0.8974471085262232	1.6498882319826529	0.0989657980709828	1.0	0.4793277390584726	3	Q96G23	1
+Chromo shadow domain [IPR008251]	0.8833333333333353	1.5976772032626074	0.1101148347644995	1.0	0.4877312250469784	3	P83916,P45973	2
+Chromo domain subgroup [IPR017984]	0.8833333333333353	1.5976772032626074	0.1101148347644995	1.0	0.4877312250469784	3	P83916,P45973	2
+N-acetylgalactosaminyltransferase [IPR045885]	0.882993197278913	1.5964178311516066	0.1103955376926324	1.0	0.4877312250469784	3	Q10472,Q86SF2	2
+HDGF-related, PWWP domain [IPR035496]	0.8760371537505948	1.5706526992903351	0.1162633418003209	1.0	0.5004741144465947	3	Q7Z4V5	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7081503235803621	1.5209766328121557	0.128265701359298	1.0	0.5193196689181335	7	Q9NZW5,Q5T2T1	2
+Guanylate kinase-like domain [IPR008144]	0.7081503235803621	1.5209766328121557	0.128265701359298	1.0	0.5193196689181335	7	Q9NZW5,Q5T2T1	2
+Alpha/beta hydrolase fold-1 [IPR000073]	0.7376238013821659	1.494963054631438	0.1349240844846315	1.0	0.5366788664005313	6	P34913	1
+Tudor domain [IPR002999]	0.6657552769320516	1.4906140968505452	0.1360628410958821	1.0	0.537772181474201	8	Q12888,Q9Y2W6	2
+L27 domain, C-terminal [IPR014775]	0.7723479436580176	1.4715909469438313	0.1411313717245714	1.0	0.5456787509226443	4	Q9NZW5,Q5T2T1	2
+CBS domain [IPR000644]	0.7301561007057688	1.3839079280682312	0.1663866488885892	1.0	0.5942806559313865	5	P51798,P51790	2
+Myosin tail [IPR002928]	0.7492344334807833	1.3825466812761262	0.1668039074776843	1.0	0.5942806559313865	4	Q92614,P35579,Q9P2M7	3
+Tyrosine-protein kinase, catalytic domain [IPR020635]	0.7481536891549763	1.3783803108073458	0.168085899115971	1.0	0.5964210173267986	4	Q15375	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7014066776918002	1.3512299736999025	0.1766217757991737	1.0	0.6037752638354805	6	Q9UIQ6	1
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7014066776918002	1.3512299736999025	0.1766217757991737	1.0	0.6037752638354805	6	Q9UIQ6	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7196153378975169	1.3426424554926393	0.1793877761053197	1.0	0.60854981267336	5	Q9NQ11,P20020	2
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9948996939816388	1.3317660149774224	0.182937088801284	1.0	0.6093183638522469	2	P05067	1
+ERAP1-like C-terminal domain [IPR024571]	0.7351025890164292	1.3280619260159234	0.1841576501032342	1.0	0.6097773254748049	4	Q9UIQ6	1
+MD-2-related lipid-recognition domain [IPR003172]	0.9857191431485894	1.298503335388064	0.1941144309443137	1.0	0.6266838514717001	2	P61916	1
+Cold-shock protein, DNA-binding [IPR002059]	0.7259020330729479	1.2925948660214628	0.196151216191158	1.0	0.6294027426752365	4	P67809	1
+Cold-shock (CSD) domain [IPR019844]	0.7259020330729479	1.2925948660214628	0.196151216191158	1.0	0.6294027426752365	4	P67809	1
+Cold shock domain [IPR011129]	0.7259020330729479	1.2925948660214628	0.196151216191158	1.0	0.6294027426752365	4	P67809	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.9819789187351244	1.284971305887378	0.1988023112818449	1.0	0.6325922782441001	2	P04066	1
+Complement Clr-like EGF domain [IPR026823]	0.9802788167290049	1.2788244180831028	0.2009588931534711	1.0	0.6344274673611094	2	Q07954	1
+Glycosyltransferase 2-like [IPR001173]	0.701198589678496	1.270500131705461	0.2039065359692791	1.0	0.637848334878775	5	Q10472,Q86SF2	2
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.9731383883032994	1.25303694483906	0.2101922617010754	1.0	0.6470617216895674	2	P06865	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.9731383883032994	1.25303694483906	0.2101922617010754	1.0	0.6470617216895674	2	P06865	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.9710982658959546	1.2456783388419796	0.2128825091194199	1.0	0.6512007957092821	2	Q5KU26	1
+C-type lectin-like [IPR001304]	0.9710982658959546	1.2456783388419796	0.2128825091194199	1.0	0.6512007957092821	2	Q5KU26	1
+L27 domain [IPR004172]	0.694626299104258	1.2447560736271577	0.213221427243174	1.0	0.6514372439699427	5	Q9NZW5,O14936,Q5T2T1	3
+CUB domain [IPR000859]	0.9656579394763712	1.226076984060405	0.2201697061599186	1.0	0.6527070032909532	2	Q6UXD5	1
+CD80-like, immunoglobulin C2-set [IPR013162]	0.954437266235975	1.1857576291408238	0.235718028726259	1.0	0.6692564327575655	2	P43121	1
+Chromo domain [IPR023780]	0.6256489231861255	1.1765471790424131	0.2393762910612622	1.0	0.6748490798861978	7	P83916,P45973	2
+PSI domain [IPR016201]	0.9333560013600828	1.11047337265192	0.2667950960719434	1.0	0.718960810843224	2	P05556	1
+IPT domain [IPR002909]	0.9316558993539614	1.1044325688249572	0.2694055393297558	1.0	0.7235783526885874	2	O15031	1
+Chromo/chromo shadow domain [IPR000953]	0.5645473497588671	1.0815528272325123	0.2794512751270299	1.0	0.7298811806238628	9	P83916,P45973	2
+Major facilitator superfamily domain [IPR020846]	0.6387188654247897	1.026639616932581	0.3045901920098917	1.0	0.7668650941401721	5	Q7L0J3	1
+Kinesin-like [IPR022164]	0.8962937776266595	0.9800683205436452	0.3270523954672322	1.0	0.7852996516730979	2	Q9NQT8	1
+Amino acid transporter, transmembrane domain [IPR013057]	0.8854131247874929	0.9423835334508296	0.3459963146402267	1.0	0.8075631082241281	2	Q96QD8	1
+EF-hand, Ca insensitive [IPR014837]	0.6979989247372899	0.9170970869297126	0.3590917674242722	1.0	0.8120821083911355	3	P12814	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]	0.511333379365246	0.911471942575155	0.3620467624125951	1.0	0.8120821083911355	11	Q9UNP9,Q96BP3	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8741924515470934	0.9038638500470914	0.3660675998739604	1.0	0.8120821083911355	2	Q96RQ1	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8741924515470934	0.9038638500470914	0.3660675998739604	1.0	0.8120821083911355	2	Q96RQ1	1
+EH domain-containing protein, N-terminal [IPR031692]	0.869092145528733	0.8864796481325515	0.3753591163161176	1.0	0.820455437194153	2	Q9H223	1
+Domain of unknown function DUF5600 [IPR040990]	0.869092145528733	0.8864796481325515	0.3753591163161176	1.0	0.820455437194153	2	Q9H223	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.6886653920533059	0.8841435979671287	0.3766187006879185	1.0	0.820455437194153	3	P20020	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.6886653920533059	0.8841435979671287	0.3766187006879185	1.0	0.820455437194153	3	P20020	1
+Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]	0.5822479337645603	0.8786690871604628	0.379580724395435	1.0	0.8254637587289373	6	Q8NC60	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.680952380952374	0.8571148718095711	0.3913814029187323	1.0	0.8284361912893662	3	O00469,Q02809	2
+RNA-binding domain, S1 [IPR022967]	0.5112321134591538	0.8120680988932616	0.4167525569979671	1.0	0.8498885069000313	8	Q7KZ85,Q9Y3B2,Q8N5C6	3
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.663265306122452	0.7959150705872533	0.4260814010583695	1.0	0.8560437848404634	3	Q10567,P63010	2
+Legume-like lectin [IPR005052]	0.8384903094185681	0.7840470311327075	0.4330125142749663	1.0	0.8597381864577174	2	Q12907	1
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.5100231740445073	0.6992825013358243	0.4843755005114496	1.0	0.892742410269067	7	Q15375	1
+F-BAR domain [IPR031160]	0.8075484529071781	0.6843742914023685	0.4937388456903999	1.0	0.8945030709744003	2	Q9UNF0	1
+FCH domain [IPR001060]	0.8075484529071781	0.6843742914023685	0.4937388456903999	1.0	0.8945030709744003	2	Q9UNF0	1
+YqgF/RNase H-like domain [IPR006641]	0.7766065963957833	0.5895886648855453	0.5554664528844007	1.0	0.9364278497509632	2	Q8N5C6	1
+HHH domain 9 [IPR041692]	0.7766065963957833	0.5895886648855453	0.5554664528844007	1.0	0.9364278497509632	2	Q8N5C6	1
+Myotubularin-like phosphatase domain [IPR010569]	0.7742264535872219	0.5825296931334506	0.560209946909815	1.0	0.9364278497509632	2	Q13614	1
+Domain of unknown function DUF1899 [IPR015048]	0.7633458007480436	0.5507212592642121	0.5818247688640055	1.0	0.9427607253865355	2	Q9BR76	1
+Major sperm protein (MSP) domain [IPR000535]	0.5863945578231211	0.5473008603365178	0.584172052886627	1.0	0.9427607253865355	3	O95292,Q8NHP6	2
+SCP2 sterol-binding domain [IPR003033]	0.5775144818171122	0.5209592795593467	0.6023951384387545	1.0	0.9499454684689668	3	P51659	1
+Myosin, N-terminal, SH3-like [IPR004009]	0.5102942309385349	0.5087727639588077	0.6109115123364732	1.0	0.9508157249675692	4	Q92614,P35579	2
+Tim44-like domain [IPR007379]	0.7443046582794988	0.4969905761231653	0.6191956969139654	1.0	0.957043628377265	2	Q9BRJ2	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.4933650901667228	0.4569031675470725	0.6477406471665399	1.0	0.973207697168199	4	P14625,Q12931,P07900	3
+Stromalin conservative domain [IPR020839]	0.7242434546072785	0.4432843730913142	0.6575600574496483	1.0	0.9736886362582354	2	Q8WVM7	1
+STAG [IPR013721]	0.7242434546072785	0.4432843730913142	0.6575600574496483	1.0	0.9736886362582354	2	Q8WVM7	1
+ISWI, HAND domain [IPR015194]	0.7147228833730022	0.4189210437352204	0.6752738370604363	1.0	0.9800001278292636	2	O60264	1
+SLIDE domain [IPR015195]	0.7147228833730022	0.4189210437352204	0.6752738370604363	1.0	0.9800001278292636	2	O60264	1
+Serpin domain [IPR023796]	0.7126827609656584	0.4137988164474143	0.6790214508309222	1.0	0.9800001278292636	2	P35237	1
+Kinesin motor domain [IPR001752]	0.4093496266424397	0.4124409169128822	0.6800162778744365	1.0	0.9800001278292636	9	Q9NQT8,O00139	2
+Dehydrogenase, E1 component [IPR001017]	0.7099625977558662	0.407024288835651	0.683990149035133	1.0	0.9800001278292636	2	P08559	1
+ERM family, FERM domain C-lobe [IPR041789]	0.5343537414965961	0.4021712530181744	0.6875579969870087	1.0	0.9800001278292636	3	P26038,P35241	2
+EB1, C-terminal [IPR004953]	0.705882352941177	0.3969819337705918	0.6913807830776273	1.0	0.981496651021043	2	Q15691	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.7035022101326137	0.3911908436715726	0.6956561758412478	1.0	0.9836365007636044	2	P31949	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.3883338292075206	0.385132642604084	0.7001391445338556	1.0	0.9870130345847492	12	P62942	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.6909214552873189	0.3614190168833417	0.7177862339975951	1.0	0.9878356513543284	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6909214552873189	0.3614190168833417	0.7177862339975951	1.0	0.9878356513543284	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6909214552873189	0.3614190168833417	0.7177862339975951	1.0	0.9878356513543284	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.6909214552873189	0.3614190168833417	0.7177862339975951	1.0	0.9878356513543284	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6909214552873189	0.3614190168833417	0.7177862339975951	1.0	0.9878356513543284	2	A0FGR8	1
+MIRO domain [IPR020860]	0.6892213532812033	0.3575059552776145	0.7207130687192473	1.0	0.9879515994531	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.6892213532812033	0.3575059552776145	0.7207130687192473	1.0	0.9879515994531	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.6892213532812033	0.3575059552776145	0.7207130687192473	1.0	0.9879515994531	2	Q8IXI1	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.4157192118676884	0.3518267329881141	0.7249682087329392	1.0	0.9879515994531	7	Q9H223	1
+Dynamin, N-terminal [IPR045063]	0.4157192118676884	0.3518267329881141	0.7249682087329392	1.0	0.9879515994531	7	Q9H223	1
+IBR domain [IPR002867]	0.6837810268616177	0.3451640902590417	0.7299710134992698	1.0	0.9879515994531	2	Q9UBS8	1
+TRIAD supradomain [IPR044066]	0.6837810268616177	0.3451640902590417	0.7299710134992698	1.0	0.9879515994531	2	Q9UBS8	1
+DDT domain [IPR018501]	0.4453895882953362	0.3249457366631771	0.7452221407011501	1.0	0.9879515994531	4	Q12830,Q9NRL2,Q9UIG0	3
+WHIM2 domain [IPR028941]	0.4453895882953362	0.3249457366631771	0.7452221407011501	1.0	0.9879515994531	4	Q12830,Q9NRL2,Q9UIG0	3
+EH domain [IPR000261]	0.441746997150086	0.3159534264640521	0.7520378589144798	1.0	0.9879515994531	4	Q9H4M9,Q9H223	2
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.4028627038926147	0.3106199722653178	0.7560895420995193	1.0	0.9879515994531	7	P11310	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.4028627038926147	0.3106199722653178	0.7560895420995193	1.0	0.9879515994531	7	P11310	1
+Phospholipid/glycerol acyltransferase [IPR002123]	0.4251191286589411	0.2960205990935707	0.7672143502171118	1.0	0.9879515994531	5	Q92604,O15228,Q8NF37,Q99943	4
+Choline/carnitine acyltransferase domain [IPR039551]	0.6599795987759292	0.2944844554018174	0.768387739882249	1.0	0.9879515994531	2	P50416	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.4874638231184377	0.2935856425616271	0.7690745481298746	1.0	0.9879515994531	3	Q96G23	1
+Lamin tail domain [IPR001322]	0.4874149659863863	0.2934849521869934	0.7691514997852307	1.0	0.9879515994531	3	P02545,Q03252	2
+WSTF/Acf1/Cbp146 [IPR013136]	0.6490989459367607	0.2731705771257783	0.7847220961679728	1.0	0.9879515994531	2	Q9UIG0	1
+Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]	0.6456987419245224	0.266754142347077	0.789658464237113	1.0	0.9879515994531	2	Q13243	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.6439986399183999	0.2635898483243453	0.7920959818241637	1.0	0.9879515994531	2	P22392	1
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.6412784767086075	0.2585880728572282	0.7959530868013174	1.0	0.9879515994531	2	Q8N983	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.4571428571428616	0.2363961413201468	0.8131252901356969	1.0	0.9879515994531	3	O00505,P52294	2
+Fxr1, tudor domain [IPR041560]	0.4568027210884392	0.2358156522373354	0.8135757219145467	1.0	0.9879515994531	3	Q06787,P51116	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.4568027210884392	0.2358156522373354	0.8135757219145467	1.0	0.9879515994531	3	Q06787,P51116	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.4568027210884392	0.2358156522373354	0.8135757219145467	1.0	0.9879515994531	3	Q06787,P51116	2
+Agenet-like domain [IPR008395]	0.4568027210884392	0.2358156522373354	0.8135757219145467	1.0	0.9879515994531	3	Q06787,P51116	2
+ZU5 domain [IPR000906]	0.6266575994559731	0.232999353318619	0.8157619079278329	1.0	0.9879515994531	2	Q07157	1
+Nuclear transport factor 2 domain [IPR002075]	0.3984348417829161	0.2216257099615521	0.8246052665114953	1.0	0.9879515994531	4	Q9UN86,Q9UBU9,Q13283	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3984348417829161	0.2216257099615521	0.8246052665114953	1.0	0.9879515994531	4	Q9UN86,Q9UBU9,Q13283	3
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.4455782312925211	0.2174274179115792	0.8278752658415176	1.0	0.9879515994531	3	Q5BKZ1,O43823	2
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.4448979591836787	0.2163609079159915	0.828706435531239	1.0	0.9879515994531	3	P00387,P16435	2
+TGS [IPR004095]	0.3775961865849394	0.2007411273871795	0.8409009992301928	1.0	0.9879515994531	6	Q9Y295,Q9BW92,P26639,Q9NTK5,P55039	5
+Myosin head, motor domain [IPR001609]	0.3526642105603846	0.1704592942194338	0.864648944322975	1.0	0.9879515994531	7	Q92614,P35579	2
+FAD/NAD(P)-binding domain [IPR023753]	0.3679288461551065	0.1702200092991688	0.8648371162073007	1.0	0.9879515994531	5	Q16881,O95831	2
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.4108843537414983	0.1699500337129031	0.8650494322051541	1.0	0.9879515994531	3	Q9BUJ2,Q1KMD3	2
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.5814348860931746	0.1677212116140577	0.8668026081200217	1.0	0.9879515994531	2	O94979	1
+FF domain [IPR002713]	0.5783747024821582	0.1640497011242028	0.8696920179316414	1.0	0.9879515994531	2	O14776	1
+Small-subunit processome, Utp12 [IPR007148]	0.404081632653059	0.1622602897495389	0.8711008844114181	1.0	0.9879515994531	3	Q15061,Q9UNX4	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5732743964637913	0.1581345036109362	0.8743508127097124	1.0	0.9879515994531	2	Q96AE4	1
+Ribosomal protein S10 domain [IPR027486]	0.5617137028221745	0.1456548508885004	0.8841938649224668	1.0	0.9879515994531	2	P60866	1
+Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]	0.347375186104094	0.1420915920430898	0.8870076593695317	1.0	0.9879515994531	4	Q6PI48	1
+C-CAP/cofactor C-like domain [IPR017901]	0.5572934376062667	0.1412166268323224	0.8876988113892619	1.0	0.9879515994531	2	Q01518	1
+CARP motif [IPR006599]	0.5572934376062667	0.1412166268323224	0.8876988113892619	1.0	0.9879515994531	2	Q01518	1
+Beta-Casp domain [IPR022712]	0.3775510204081636	0.1370333205861489	0.8910044575194722	1.0	0.9879515994531	3	Q5TA45,Q9UKF6	2
+Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]	0.3775510204081636	0.1370333205861489	0.8910044575194722	1.0	0.9879515994531	3	Q5TA45,Q9UKF6	2
+OCRE domain [IPR041591]	0.5518531111866767	0.1360013865519758	0.8918201848403462	1.0	0.9879515994531	2	P98175	1
+MoaB/Mog domain [IPR001453]	0.5419925195511756	0.1272266529760398	0.8987610107656152	1.0	0.9879515994531	2	Q8NFF5	1
+YTH domain [IPR007275]	0.3337131750734544	0.1265893664540948	0.899265413569363	1.0	0.9879515994531	4	Q96MU7	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.5382522951377192	0.1241208170678279	0.9012196159740128	1.0	0.9879515994531	2	P55010	1
+Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]	0.5294117647058946	0.1172494972804383	0.9066623442240968	1.0	0.9879515994531	2	P13804	1
+Disulphide isomerase [IPR005788]	0.3311776718856402	0.1132168807525335	0.9098586128103678	1.0	0.9879515994531	5	P07237,P13667,P30101,Q8NBS9	4
+Putative WW-binding domain and destruction box [IPR033461]	0.5215912954777401	0.1117022978126366	0.911059457343943	1.0	0.9879515994531	2	Q8TF05	1
+Vps4 oligomerisation, C-terminal [IPR015415]	0.3370748299319785	0.1115022537452207	0.911218078515583	1.0	0.9879515994531	3	O75351,Q9UN37	2
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.3172815468164574	0.1109516143678454	0.9116547158825856	1.0	0.9879515994531	4	Q13614	1
+Domain of unknown function DUF1747 [IPR013719]	0.5202312138728455	0.1107868014706991	0.9117854118190252	1.0	0.9879515994531	2	Q08945	1
+Thioredoxin domain [IPR013766]	0.3457796210948145	0.1080116088181008	0.9139864835812754	1.0	0.9879515994531	26	Q6ZRP7,Q9H3N1,Q9Y2G8	3
+3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]	0.5103706222373328	0.1045693125660899	0.9167175661939508	1.0	0.9879515994531	2	Q49A26	1
+Nop domain [IPR002687]	0.3187074829932026	0.1041443308353601	0.9170548111869008	1.0	0.9879515994531	3	Q9Y2X3,Q8WWY3	2
+NOSIC [IPR012976]	0.3187074829932026	0.1041443308353601	0.9170548111869008	1.0	0.9879515994531	3	Q9Y2X3,Q8WWY3	2
+Translation initiation factor, beta propellor-like domain [IPR013979]	0.3045253487580797	0.1009251940333134	0.9196098432713102	1.0	0.9879515994531	4	Q9BY44,Q96J01,P55884	3
+Methioninyl-tRNA synthetase core domain [IPR033911]	0.5032301938116426	0.1005097102845491	0.919939674184443	1.0	0.9879515994531	2	P56192	1
+Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]	0.5032301938116426	0.1005097102845491	0.919939674184443	1.0	0.9879515994531	2	P56192	1
+Methionyl/Leucyl tRNA synthetase [IPR015413]	0.5032301938116426	0.1005097102845491	0.919939674184443	1.0	0.9879515994531	2	P56192	1
+Chromatin target of PRMT1 protein, C-terminal [IPR025715]	0.501870112206743	0.0997768718647899	0.9205214699841322	1.0	0.9879515994531	2	Q86V81	1
+Translation elongation factor EFG/EF2, domain IV [IPR005517]	0.2952380952381006	0.097671855132707	0.9221928650230936	1.0	0.9879515994531	3	Q96RP9,Q15029	2
+CLASP N-terminal domain [IPR024395]	0.4960897653859242	0.096801661428137	0.9228839045041964	1.0	0.9879515994531	2	Q7Z460	1
+RasGAP protein, C-terminal [IPR000593]	0.4841890513430925	0.0913525319060434	0.9272124780225156	1.0	0.9879515994531	2	Q13576	1
+CELF1/2, RNA recognition motif 1 [IPR034196]	0.4807888473308556	0.0899534350244076	0.9283242182149992	1.0	0.9879515994531	2	O95319	1
+CELF1/2, RNA recognition motif 3 [IPR034199]	0.4807888473308556	0.0899534350244076	0.9283242182149992	1.0	0.9879515994531	2	O95319	1
+CELF1/2, RNA recognition motif 2 [IPR034198]	0.4807888473308556	0.0899534350244076	0.9283242182149992	1.0	0.9879515994531	2	O95319	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.3126702997275228	0.0863947749139633	0.931152600416483	1.0	0.9879515994531	7	O14818,P25789,P25787,P60900,P25788,P25786	6
+NUC153 [IPR012580]	0.4705882352941341	0.086146395456272	0.9313500424393228	1.0	0.9879515994531	2	Q9H501	1
+Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]	0.4665079904794268	0.0847786099648247	0.9324373990822504	1.0	0.9879515994531	2	Q9H4A4	1
+SUN coiled coil domain 2 [IPR040994]	0.4654879292757651	0.0844498232384079	0.9326987955145454	1.0	0.9879515994531	2	Q9UH99	1
+LEM domain [IPR003887]	0.3144487249639213	0.0844042918481013	0.9327349950638346	1.0	0.9879515994531	6	Q8NC56,P50402	2
+SMARCC, N-terminal [IPR032450]	0.4532471948317023	0.0808911382401124	0.9355285275306529	1.0	0.9879515994531	2	Q8TAQ2	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.4532471948317023	0.0808911382401124	0.9355285275306529	1.0	0.9879515994531	2	Q8TAQ2	1
+SMARCC, C-terminal [IPR032451]	0.4532471948317023	0.0808911382401124	0.9355285275306529	1.0	0.9879515994531	2	Q8TAQ2	1
+2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]	0.4416865011900855	0.0781291102864708	0.9377253513029462	1.0	0.9879515994531	2	P21912	1
+Thioesterase domain [IPR006683]	0.4372662359741577	0.0772106953708259	0.9384559333724114	1.0	0.9879515994531	2	Q9NPJ3	1
+Pumilio homology domain [IPR033133]	0.434886093165602	0.0767453827471202	0.938826100765792	1.0	0.9879515994531	2	Q14671	1
+ENTH  domain [IPR013809]	0.4345460727643706	0.0766805287484517	0.9388776947343644	1.0	0.9879515994531	2	Q14677	1
+Acyltransferase, C-terminal domain [IPR032098]	0.424685481128874	0.0749664321984101	0.9402414199364484	1.0	0.9879515994531	2	Q92604	1
+Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]	0.4178850731043925	0.0739581291049547	0.9410437021081242	1.0	0.9879515994531	2	Q9UN37	1
+Zinc finger, UBR-type [IPR003126]	0.4168650119007149	0.0738181351699397	0.9411550966152776	1.0	0.9879515994531	2	Q5T4S7	1
+Ribosomal protein L11, C-terminal [IPR020783]	0.4087045222713387	0.0727958613840605	0.9419685643578152	1.0	0.9879515994531	2	Q9Y3B7	1
+Ribosomal protein L11, N-terminal [IPR020784]	0.4087045222713387	0.0727958613840605	0.9419685643578152	1.0	0.9879515994531	2	Q9Y3B7	1
+Thioredoxin-like fold [IPR012336]	0.386603196191776	0.0707704701069729	0.9435804343180724	1.0	0.9879515994531	2	Q6DKJ4	1
+Butyrophylin-like, SPRY domain [IPR003879]	0.2300102075535853	0.0707590579764059	0.943589517110632	1.0	0.9879515994531	4	Q12899,Q8WW59,Q14258	3
+LEM-like domain [IPR013146]	0.3134988099285898	0.0684357739562011	0.9454387450725452	1.0	0.9879515994531	2	P42166	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.3039782386943163	0.0683620203825201	0.9454974544163604	1.0	0.9879515994531	2	Q9H993	1
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.2821965957106548	0.0473607298420314	0.9622257269245548	1.0	0.9987253272372412	6	O94973	1
+OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]	0.2334921715452749	0.0425191427201939	0.9660848518649424	1.0	1.0	5	P14868,Q15046,Q6PI48,O43776	4
+S1 domain [IPR003029]	0.2704359673024554	0.026154753044609	0.9791339053632886	1.0	1.0	7	Q14562,Q7KZ85,Q8TCS8,P05198,Q8N5C6,Q14690	6
+Aminotransferase, class I/classII [IPR004839]	0.1961184882533198	0.0053655944280932	0.9957188955881876	1.0	1.0	6	P17174,O15269,P00505,Q6YP21,O75600	5

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]", "1": "Syntaxin [IPR045242]", "2": "Proteasome, subunit alpha/beta [IPR001353]", "3": "Small GTPase [IPR001806]", "4": "Proteasome alpha-type subunit [IPR023332]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:0c05a61735a5e624f747cd0da6af0651dd7671e0839d195e1ec0dd3b8a17a181
+size 209234