msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Protein localization	0.6077101592874667	3.691038276717813	0.0002233405218388	0.2647717227866972	0.0512566497620072	71	Q13505,Q15067,Q99595,O00116,Q9Y5J9,P21796,O60830,P46379,Q10713,Q13011,Q9Y584,O75521,Q2T9J0,P09601,O75874,Q5JRX3,P06576,Q9NS69,P05067,Q8N4H5,Q15388,Q8NBU5	22
Mitochondrial protein import	0.6719123382840052	3.3473579105902997	0.0008158580026007	0.6749885938145838	0.1404295586976552	35	Q13505,Q99595,Q9Y5J9,Q9Y584,Q5JRX3,Q15388,P21796,P06576,O60830,Q9NS69,Q10713	11
Glycosphingolipid metabolism	0.8361322673010358	3.0987944351716252	0.0019430978858336	0.9313166647501252	0.1554997011416702	14	P06865,P06280,P07602,P10619,Q13510,P04062	6
Sphingolipid metabolism	0.7173957366068304	3.0901782072907085	0.0020003643420385	0.9365345986373416	0.1554997011416702	24	P06865,Q96G23,P27544,P06280,P07602,P10619,Q13510,P04062	8
Glycosaminoglycan metabolism	0.7596133067302653	2.630720647873834	0.0085204040094897	0.9999923657457284	0.204789780381728	13	P06865,P54802,P15586,Q8NCH0,Q8TB61,O43505	6
Mrna splicing	0.4692964070755708	2.4863937060435344	0.0129045113344774	0.9999999829166504	0.2538501729653636	145	P62995,Q9BUJ2,O60828,P17844,Q8WYA6,Q07955,Q13243,P22626,P19388,O60508,P08621,O43390,Q13151,Q7RTV0,P07910,Q9BZJ0,O95400,O75494,Q8IWZ8,O75934,O43290,Q13242,Q8N684,Q15637,Q8IWX8,P09651,Q9Y3B4,Q9Y4Z0,Q5KU26,Q14103,Q08170,P61978,P26368,Q15427,O94992,P51991,Q8WWY3,Q9BXP5,P31943,Q92733,P67809,P52597,Q6UN15,Q15717,Q96I25,Q05048,Q9UKF6,Q92797,O43395,P52434,Q15287,P62304,P35637,P41223,Q16629,P55795,Q9UNP9,P52272,P84103,P38159	60
Unwinding of dna	0.8111084258534983	2.4743483161938338	0.0133479488484595	0.9999999907984756	0.2552795217267894	9	Q14566	1
Metabolism of porphyrins	0.7641886745220521	2.379826036861595	0.0173208128742696	0.9999999999644376	0.3019083459223967	10	P22830,P30519	2
Deubiquitination	0.4490798144187999	2.284749446186882	0.0223275234776916	0.9999999999999688	0.3454494362784424	80	P45880,P20618,O14964,Q93009,Q99436,P49721,Q15388,Q8NB78,P21796,P60900,Q7Z434,Q96FW1,P28074,P51784,P28072,Q96K76	16
Pink1 prkn mediated mitophagy	0.7879281847705359	2.215439981883285	0.0267298796028654	1.0	0.3755820838076092	8	P21796,Q13501,Q15388,Q9NS69	4
Mitophagy	0.7049177229063407	2.199520502106082	0.0278409329608808	1.0	0.3872420675467974	11	P21796,Q13501,Q15388,Q9NS69	4
Plasma lipoprotein clearance	0.6584813270984133	2.1628224989440663	0.0305548344376092	1.0	0.4082322961389796	14	Q6PIU2,P61916,O15118,Q8WTV0,P01130	5
The citric acid tca cycle and respiratory electron transport	0.41149345638495	2.1569010319784487	0.0310133765218869	1.0	0.4082322961389796	94	Q9Y6N1,Q9H9P8,P25705,O43837,O75306,P21796,P03886,Q9Y6M9,O96000,P11177,O75489,P48735,Q9NPL8,Q7L592,P20674,Q9BQ95,Q9UDW1,Q15120,P06576,Q13423,P00846,O95298,P53985,O75964,O43676	25
Ub specific processing proteases	0.4528843789319017	2.102302790525371	0.0355267602993751	1.0	0.4488105406627489	65	P45880,P20618,O14964,Q93009,Q99436,P49721,Q15388,P60900,P21796,Q96FW1,Q96K76,P28074,P28072,P51784	14
Diseases of glycosylation	0.6179045923041075	2.0772712365216255	0.0377765322596939	1.0	0.460338804615916	16	P06865,P10619,Q8NCH0,Q13724	4
Plasma lipoprotein assembly remodeling and clearance	0.6060195333218743	2.055861118806509	0.0397959047840892	1.0	0.476512703371225	17	Q6PIU2,P61916,O15118,Q8WTV0,P01130	5
Gpcr ligand binding	0.7205610125172222	2.047631337954392	0.0405961362976008	1.0	0.4819041351878996	9	P07602,P42892,Q9NRV9	3
Collagen biosynthesis and modifying enzymes	0.6685777028082502	2.0109309292345405	0.0443327528846129	1.0	0.5045140555546445	11	O75718,P13674	2
Cargo recognition for clathrin mediated endocytosis	0.5010490098093111	1.9982621445532975	0.045688247290994	1.0	0.5052394974611952	33	Q7L5N1,Q9UHD9,O14964,P98164,P01130,O43493,P02786,P09496,Q14108,O14656,P61201,P11717,Q96D71	13
Formation of atp by chemiosmotic coupling	0.682256840662744	1.973923728177586	0.0483904162461581	1.0	0.527795399274835	10	O75964,P00846	2
Assembly and cell surface presentation of nmda receptors	0.6610574759404452	1.9713986309212004	0.0486782975366042	1.0	0.527795399274835	11	Q9BVA1,Q14168,O14936,Q15334,P07196	5
Phase i functionalization of compounds	0.6175520951482962	1.931567624949909	0.053412895036849	1.0	0.5437363544755964	14	P07099,P30837,Q16850	3
Transport of small molecules	0.4249234963777972	1.9121179274923816	0.0558610698869139	1.0	0.553386282261011	147	Q9Y487,Q8NEW0,Q9HD20,P08183,P21796,P30519,Q8WTV0,P28072,Q10713,P45880,Q6PIU2,Q70HW3,Q9H2J7,O15118,Q8TB61,P09601,P20618,Q9C0H2,P30825,Q99436,Q9NQ11,Q96QD8,P53985,Q9UL46,P49721,P60900,P61916,Q8N4V1,Q93050,P28074,P01130	31
Organelle biogenesis and maintenance	0.397135283343395	1.883565023438459	0.059623836693321	1.0	0.5658227913405848	90	P48735,Q13505,P53350,Q96KP1,O95684,O00411,A6NIH7,O75964,O43805,O00471,Q9H6D7,P06576,O75935,P16220,P00846	15
Collagen formation	0.6201241660703272	1.8813675938954932	0.0599219319307648	1.0	0.5658227913405848	13	O75718,P13674	2
Rna polymerase ii transcription termination	0.4426353420553575	1.8701160593414037	0.061467702838942	1.0	0.5658227913405848	47	Q9BY77,Q01081,Q07955,Q13243,O60508,P33240,Q86V81,Q13242,Q8N684,Q5KU26,Q08170,P26368,O94992,Q6UN15,Q9UKF6,Q05048,Q92797,P82979,Q15287,P62304,Q16629,O43809,P84103	23
Tysnd1 cleaves peroxisomal proteins	0.8933576227451177	1.8614777100636544	0.0626767455071297	1.0	0.5658227913405848	5	O00116,Q2T9J0	2
Slc mediated transmembrane transport	0.5345859887183926	1.854732575831516	0.0636344244651847	1.0	0.5658227913405848	23	P53985,P30825,Q70HW3,Q9H2J7,Q8TB61,Q96QD8	6
Switching of origins to a post replicative state	0.4363843705095661	1.854092823174684	0.0637258812978545	1.0	0.5658227913405848	56	P20618,Q96DE5,Q9UJX3,Q14566,Q9UL46,Q9UJX6,Q99436,P49721,P60900,P28074,P33991,P28072	12
Notch2 intracellular domain regulates transcription	0.92485549132948	1.849204029919059	0.0644283570556387	1.0	0.5658227913405848	2	P16220	1
Purine salvage	0.7686902732592525	1.8439708102290555	0.0651873942908538	1.0	0.5658227913405848	6	P00813	1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.4443115368262302	1.843632751945828	0.0652366795222916	1.0	0.5658227913405848	45	P20618,Q96DE5,P53350,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,P60900,P28074,P28072	11
Peptide ligand binding receptors	0.7452467107781795	1.842341124850676	0.0654252678356464	1.0	0.5658227913405848	7	P07602,P42892,Q9NRV9	3
Class a 1 rhodopsin like receptors	0.7452467107781795	1.842341124850676	0.0654252678356464	1.0	0.5658227913405848	7	P07602,P42892,Q9NRV9	3
Keratan sulfate keratin metabolism	0.8865389698449088	1.834076078560251	0.0666427017795945	1.0	0.5658227913405848	5	P06865,P15586	2
Peroxisomal protein import	0.5470533850181339	1.8172445356076232	0.0691796784646987	1.0	0.567030974981668	20	Q13011,Q15067,O75874,O00116,Q08426,O75521,Q2T9J0	7
Interleukin 12 signaling	0.5199920567568944	1.7819902690982303	0.0747508186011094	1.0	0.567030974981668	24	P14174,Q13126,O14979,P52597	4
Sphingolipid de novo biosynthesis	0.6446431274780868	1.781223080336381	0.0748760145879507	1.0	0.567030974981668	10	Q96G23	1
Ldl clearance	0.6135456909998277	1.7783207805602006	0.0753511852717851	1.0	0.567030974981668	12	O15118,P61916,P01130,Q6PIU2	4
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.550211121037507	1.757303339834357	0.0788661188358186	1.0	0.567030974981668	18	O43852,Q8NBJ4,Q9BTY2,P05067	4
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.5242777921979205	1.7545363307573438	0.0793386503012321	1.0	0.567030974981668	22	P14174,Q13126,O14979,P52597	4
Cell surface interactions at the vascular wall	0.5629796652339817	1.7443896234442222	0.0810911731594736	1.0	0.567030974981668	16	Q92896,P53985,P14174,Q9Y624,P05026,P07947	6
Cristae formation	0.5322822848313176	1.7187078476185058	0.0856675823736858	1.0	0.567030974981668	20	Q16891,P36542,Q13505,Q9NX63,P25705,O75964,P06576,Q9BUR5,Q9Y512,P00846	10
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.6126326011483632	1.7128079691436422	0.0867478735578037	1.0	0.567030974981668	11	P09601,P05067,P46379	3
Fgfr2 alternative splicing	0.5558262338284667	1.7001886673694588	0.0890954432237416	1.0	0.567030974981668	16	Q01085,P52597,P52434,P52272,P19388,P31483,P31943,P09651	8
Rhobtb1 gtpase cycle	0.533725496616162	1.687952474751637	0.0914203522985324	1.0	0.5712178352449779	19	P62995,Q5VTR2,P38159,O43396,P61201,P08670	6
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.4133051633484473	1.6771925413724598	0.0935048370873243	1.0	0.5712178352449779	64	Q9Y6N1,P25705,O75306,P03886,Q9Y6M9,O96000,O43674,O75489,Q9NPL8,Q7L592,P20674,Q9BQ95,O75880,Q9UDW1,P06576,P00846,O95298,O75964,O43676,P13073,P10606	21
Amino acid transport across the plasma membrane	0.7295050723035242	1.6717140063110651	0.094580730890236	1.0	0.5712178352449779	6	P30825,Q9H2J7	2
Processing of capped intron containing pre mrna	0.4303824337969155	1.6326319015476936	0.1025464375735218	1.0	0.5812213782660979	185	Q9BY77,P62995,P57740,Q99567,Q9BUJ2,O60828,P17844,Q8WYA6,Q07955,Q13243,P22626,P19388,O60508,P08621,O43390,Q13151,Q7RTV0,Q96EE3,Q8N1F7,Q9BZJ0,P07910,O95400,Q8NFH4,O75494,Q8IWZ8,O75934,O43290,Q13242,Q8N684,Q15637,Q8IWX8,P09651,Q9Y3B4,Q9Y4Z0,Q5KU26,Q14103,Q08170,P61978,Q12769,Q86U44,P26368,Q15427,P37198,O94992,P51991,Q8WWY3,Q9BXP5,P31943,Q92733,P67809,P52597,Q6UN15,Q15717,Q96I25,Q05048,Q9BTX1,Q9UKF6,Q92797,P82979,O43395,P52434,P62304,Q15287,P35637,P41223,Q16629,P55795,Q9UNP9,P52272,P84103,P38159	71
Rhobtb gtpase cycle	0.4822819464900643	1.6325271751574304	0.1025684785175466	1.0	0.5812213782660979	28	P62995,Q9NYL9,Q5VTR2,P38159,Q12792,P61201,P08670	7
Orc1 removal from chromatin	0.4151245234247158	1.6036894686200016	0.1087825184222364	1.0	0.594418761378649	48	Q14566,Q99436,P49721,P60900,P28074,P33991	6
Phosphorylation of the apc c	0.5911110327244108	1.595755924719015	0.1105432972322435	1.0	0.5990152741088558	11	P53350,Q9UJX3,Q96DE5,Q9UJX6	4
Metabolism of folate and pterines	0.652899475380003	1.5845069004749446	0.113078412591923	1.0	0.6039881246156056	8	Q9H2D1,P34897,P00374	3
Apc c mediated degradation of cell cycle proteins	0.4115469701568277	1.5815741612673473	0.1137468165205082	1.0	0.6039881246156056	52	P20618,Q96DE5,P53350,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,P60900,P28074,P28072	11
Peroxisomal lipid metabolism	0.624646110120028	1.5725503461685044	0.1158229727583122	1.0	0.6039881246156056	9	O75521,Q15067	2
Interferon gamma signaling	0.5657618036219042	1.571948728790881	0.1159624422700322	1.0	0.6039881246156056	13	P15260,P10321,P19474,O75925	4
Interleukin 12 family signaling	0.478239290578631	1.567733164187349	0.116943418516346	1.0	0.6039881246156056	27	P14174,Q13126,O14979,P52597	4
Activation of atr in response to replication stress	0.5208059981540651	1.5667740311850258	0.1171675194478105	1.0	0.6039881246156056	18	O60921,P33991,P30307,Q14566	4
Mitochondrial biogenesis	0.4459374453627564	1.5592764238489476	0.1189309693183771	1.0	0.6039881246156056	34	Q16891,P48735,Q13505,Q86X55,Q9NX63,P25705,P00367,O00411,O75964,Q04837,P06576,Q96RR1,Q9BUR5,P16220,Q9Y512,P00846	16
Peptide hormone metabolism	0.5434059447200332	1.5576578125533298	0.1193143861611762	1.0	0.6039881246156056	15	Q96KP1,P33176,Q99626,O00471	4
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.5723514054538292	1.492762608157156	0.1354993383094926	1.0	0.6471036584282167	11	Q9UJX3,Q96DE5,Q9UJX6	3
Apc cdc20 mediated degradation of nek2a	0.5723514054538292	1.492762608157156	0.1354993383094926	1.0	0.6471036584282167	11	Q9UJX3,Q96DE5,Q9UJX6	3
Transport of inorganic cations anions and amino acids oligopeptides	0.5623969001159916	1.4924869621112344	0.1355715326659199	1.0	0.6471036584282167	12	Q70HW3,P30825,Q9H2J7	3
Linoleic acid la metabolism	0.8415504930295825	1.4753744983400034	0.1401118875682239	1.0	0.6524004953337048	2	P33121	1
Glycerophospholipid biosynthesis	0.4738641929175701	1.4753573243145888	0.1401165023032629	1.0	0.6524004953337048	25	Q8IV08,P48651,Q6P1A2,Q8N2A8,Q9NPH0,Q8NCC3	6
Mucopolysaccharidoses	0.9385829244748618	1.4744063741637752	0.1403722092630652	1.0	0.6524004953337048	3	P54802	1
Synthesis of pa	0.6623085291745666	1.4645788263617372	0.1430358623039913	1.0	0.6524116448821732	7	Q9NPH0,Q8N2A8	2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.6250872749847584	1.4497819846653663	0.1471193248325153	1.0	0.6598804895582202	8	Q9UJX3,Q96DE5,Q9UJX6	3
Uch proteinases	0.4108675073538319	1.426880891041398	0.1536142297171099	1.0	0.6717887529593701	42	Q99436,P49721,P60900,Q8NB78,P28074	5
Pyruvate metabolism and citric acid tca cycle	0.4374126995917285	1.42666261764505	0.1536771657096598	1.0	0.6717887529593701	32	P48735,Q9H9P8,P53985,Q15120,P11177,P21796,Q13423	7
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.5901611093367303	1.3966820311704091	0.1625092100154543	1.0	0.6992974443477521	9	Q9UJX3,Q96DE5,Q9UJX6	3
Metabolism of lipids	0.3940114334481913	1.3909951610825222	0.1642268941086879	1.0	0.7032413000509392	159	Q8IV08,P48651,Q96G23,Q15067,P98164,Q6P1A2,O00116,O43772,P33121,Q16850,Q15165,P04062,Q10713,Q8NCC3,Q14914,P50897,Q14849,P38435,P27544,P06280,Q53GQ0,Q08426,Q8N8N7,O75521,Q9NZ01,Q8N9F7,Q9NPH0,Q15800,P06865,Q9UMR5,Q16836,P10619,P23786,Q13510,P43304,Q96ST3,P53992,Q8N2A8,O95772,Q99538,P17900,P42126,O15269,P07602,Q9BWD1,Q15392	46
Auf1 hnrnp d0 binds and destabilizes mrna	0.4121184803182964	1.3856022715337963	0.165868384236723	1.0	0.7032413000509392	40	P20618,Q14103,Q99436,P49721,P60900,P28074,P28072,P04792	8
Insulin processing	0.584781980818148	1.3690602075113525	0.1709804555888783	1.0	0.7208505922587513	9	Q96KP1,P33176,O00471	3
Signaling by notch2	0.9088984766472812	1.3593518363269192	0.1740351254319594	1.0	0.7208505922587513	3	P16220	1
Nucleotide salvage	0.6061321553828212	1.3572534493685555	0.174700692879316	1.0	0.7208505922587513	8	P00813	1
Transcriptional regulation by ventx	0.5478511138047626	1.3570712846354478	0.1747585614957993	1.0	0.7208505922587513	11	Q9UJX3,Q96DE5,Q9UJX6	3
Signaling by interleukins	0.3435014201164708	1.349167581698182	0.1772831449634786	1.0	0.7222452385050594	97	P52597,P16220,P14174,Q99436,P49721,P60900,P28072,P22626,P28074,O14979,Q13126,P09601,P08670	13
Interferon alpha beta signaling	0.561774941381485	1.3441786789681087	0.1788906144947648	1.0	0.7235967871756606	10	Q13325,Q9Y3Z3,P10321,P55265	4
Keratan sulfate degradation	0.8778378068380978	1.3377785375021367	0.1809686402566024	1.0	0.7235967871756606	4	P06865	1
Processing of intronless pre mrnas	0.4915205994873144	1.3328940339919804	0.1825665806926415	1.0	0.7244789095497619	17	P33240,Q6UN15,Q9UKF6,Q05048,Q5KU26,Q92797,O94992,Q8N684,O43809	9
Translation of sars cov 1 structural proteins	0.7596185273661613	1.3152706396039289	0.1884189619025797	1.0	0.7325129072043104	5	Q13724	1
Metabolism of steroid hormones	0.6497182692278589	1.314153864030242	0.188794430707913	1.0	0.7325129072043104	6	O95772,Q14849	2
Cilium assembly	0.3820801600536308	1.29372944717302	0.195758890109829	1.0	0.7428557952518208	56	P53350,Q96KP1,O95684,A6NIH7,O00471,O43805,Q9H6D7,O75935	8
Processing of capped intronless pre mrna	0.4749037978522448	1.2936749601516366	0.1957777179848412	1.0	0.7428557952518208	19	P33240,Q6UN15,Q9UKF6,Q5KU26,Q05048,Q92797,P62304,O94992,Q8N684,O43809	10
Intrinsic pathway of fibrin clot formation	0.8010880652839285	1.2935263182251484	0.1958290876371902	1.0	0.7428557952518208	2	P42785	1
Formation of fibrin clot clotting cascade	0.8010880652839285	1.2935263182251484	0.1958290876371902	1.0	0.7428557952518208	2	P42785	1
Transport of bile salts and organic acids metal ions and amine compounds	0.8637075660214498	1.284035479666216	0.1991295415104368	1.0	0.7451697350532895	4	P53985,Q9H2J7	2
Mitochondrial calcium ion transport	0.4894543465148754	1.2820610094977278	0.1998212452386967	1.0	0.7451697350532895	16	P21796	1
Striated muscle contraction	0.7511895988050004	1.2804569421440612	0.2003844786984721	1.0	0.7451697350532895	5	P08670	1
Selective autophagy	0.4331478544693442	1.2799099477227625	0.2005768086573056	1.0	0.7451697350532895	29	Q15388,P21796,P08670,Q9NS69	4
Negative regulation of nmda receptor mediated neuronal transmission	0.7509254123680958	1.2793656719085045	0.2007683164159552	1.0	0.7451697350532895	5	Q14168,Q15334,P07196	3
Ras activation upon ca2 influx through nmda receptor	0.7509254123680958	1.2793656719085045	0.2007683164159552	1.0	0.7451697350532895	5	Q14168,Q15334,P07196	3
Unblocking of nmda receptors glutamate binding and activation	0.7509254123680958	1.2793656719085045	0.2007683164159552	1.0	0.7451697350532895	5	Q14168,Q15334,P07196	3
Long term potentiation	0.7509254123680958	1.2793656719085045	0.2007683164159552	1.0	0.7451697350532895	5	Q14168,Q15334,P07196	3
Vitamin d calciferol metabolism	0.8587955086764161	1.265360953349883	0.2057419656259071	1.0	0.7554844977783312	4	Q99538,P04062,P98164	3
Antigen presentation folding assembly and peptide loading of class i mhc	0.4933909195365248	1.2494136499178623	0.2115138184479614	1.0	0.7725584297157637	15	Q9NZ08,P01889,Q03518,P53992,Q6P179,P10321	6
Transport of mature transcript to cytoplasm	0.3735517290528554	1.2463003562031802	0.2126541471549803	1.0	0.7726246982385433	64	Q9BY77,P57740,Q99567,Q07955,Q13243,Q8N1F7,O60508,Q96EE3,Q86V81,Q8NFH4,Q13242,P12270,Q12769,Q08170,P26368,P37198,Q6UN15,Q9UKF6,Q9BTX1,Q92797,P82979,Q15287,Q16629,P84103	24
Neurotransmitter release cycle	0.6332734258456862	1.239716154671804	0.2150803997924253	1.0	0.7773378228718364	6	O14936	1
Regulation of mrna stability by proteins that bind au rich elements	0.3740703312730689	1.2223403949687712	0.2215789294118422	1.0	0.7904512585494993	59	P20618,Q14103,Q92945,Q99436,P49721,Q9Y3B2,P60900,P28074,P28072,P04792	10
Apc c cdc20 mediated degradation of cyclin b	0.5337073697077838	1.1932406180532285	0.2327751512613813	1.0	0.8136461088516497	10	Q9UJX3,Q96DE5,Q9UJX6	3
Chondroitin sulfate dermatan sulfate metabolism	0.8369616444290939	1.1824584558994986	0.2370238403817814	1.0	0.8159545705142827	4	P06865	1
Diseases associated with glycosaminoglycan metabolism	0.8369616444290939	1.1824584558994986	0.2370238403817814	1.0	0.8159545705142827	4	P06865	1
Signaling by erbb4	0.6200970816780087	1.1800083939001138	0.2379968764526139	1.0	0.8172610944519934	6	P61201,Q15334	2
Interleukin 1 signaling	0.3867784714870911	1.1726315009494532	0.2409436113668228	1.0	0.823273828417159	41	P20618,P05067,Q99436,P49721,P60900,P28072,P28074,Q13501	8
Respiratory electron transport	0.3695415946035653	1.1546974664212704	0.2482143374123468	1.0	0.8256342600048767	54	Q9Y6N1,O95298,Q9NPL8,Q7L592,P20674,Q9BQ95,P13073,O75880,Q9Y6M9,O75306,O96000,O43674,O75438,Q9UDW1,O43676,O75489,P03886,P10606	18
Alpha linolenic omega3 and linoleic omega6 acid metabolism	0.719877467665087	1.1511783257381298	0.2496588800487333	1.0	0.8256342600048767	5	P22307,O95864,P33121,Q15067	4
Tight junction interactions	0.768446106766404	1.1478540295560784	0.2510288284161794	1.0	0.8256342600048767	2	Q8NI35	1
Resolution of d loop structures through synthesis dependent strand annealing sdsa	0.5935415234634227	1.1444741983932398	0.2524270322890727	1.0	0.8256342600048767	7	Q9UQ84	1
Resolution of d loop structures	0.5935415234634227	1.1444741983932398	0.2524270322890727	1.0	0.8256342600048767	7	Q9UQ84	1
Phospholipid metabolism	0.3896848863049302	1.135426435761291	0.2561966885141655	1.0	0.8287863564308652	38	Q8IV08,P48651,Q6P1A2,Q8N2A8,Q9NPH0,Q10713,Q8NCC3	7
G2 m checkpoints	0.3546525149910794	1.127549089640158	0.2595103976733566	1.0	0.829108625513253	75	O60921,P20618,Q14566,Q9UL46,Q99436,P49721,P30307,Q9UQ84,P60900,Q14191,P28074,P33991,P28072	13
Diseases of mitotic cell cycle	0.4972740310089933	1.120190165374912	0.2626327339667944	1.0	0.8335796653280813	12	Q9UJX3,Q96DE5,Q9UJX6	3
Aurka activation by tpx2	0.4050573625461499	1.1171002735118294	0.2639514535833402	1.0	0.8336264944593109	31	O75935,P53350,Q9H6D7,O95684	4
Diseases of dna repair	0.5176359082293598	1.1064913099183251	0.2685139232891864	1.0	0.8409708233367286	10	Q9UQ84	1
Ptk6 regulates proteins involved in rna processing	0.8428571428571439	1.104605596248763	0.269330525120913	1.0	0.8409708233367286	3	Q07666,O75525	2
Synthesis of very long chain fatty acyl coas	0.6022837160566206	1.0992961264071626	0.2716389214126651	1.0	0.8443494238944467	6	P33121,Q9NZ01	2
Interleukin 4 and interleukin 13 signaling	0.5007276328624122	1.0934872292486388	0.2741799331179548	1.0	0.8453313911186422	11	P09601	1
Cargo trafficking to the periciliary membrane	0.4409269508233231	1.0904664920645255	0.2755077058364628	1.0	0.8453313911186422	20	Q96KP1,A6NIH7,O00471	3
Met activates pi3k akt signaling	0.754165249914993	1.0846674298481684	0.2780689782559247	1.0	0.8457261658818525	2	Q9NWH9	1
Nrcam interactions	0.7531451887113232	1.0801706819992196	0.2800661812942082	1.0	0.8457261658818525	2	Q15334	1
Ionotropic activity of kainate receptors	0.7531451887113232	1.0801706819992196	0.2800661812942082	1.0	0.8457261658818525	2	Q15334	1
Transcriptional regulation by runx3	0.3791423070870537	1.0780164452435967	0.2810264171963827	1.0	0.84676887632258	40	P20618,Q99436,P49721,P60900,P28074,P28072,Q06330	7
Pyruvate metabolism	0.4732231836170799	1.0748489932723913	0.282442341426812	1.0	0.8476237275291774	14	P11177,P21796,P53985	3
Heme degradation	0.8077405132954434	1.0719938071070374	0.2837228137285845	1.0	0.8480566201930592	4	P30519	1
Signaling by the b cell receptor bcr	0.3714812450971448	1.0504068970525828	0.2935310759837994	1.0	0.8480566201930592	42	P20618,O43865,Q9UL46,Q99436,P49721,P60900,P28074,P28072	8
Dna replication pre initiation	0.3580593530409507	1.0498844374287066	0.2937712475178571	1.0	0.8480566201930592	59	Q14566,Q99436,P49721,P60900,P28074,P33991	6
Hdms demethylate histones	0.5690336528899143	1.029996386279334	0.3030117019598028	1.0	0.8638656596245312	7	Q8NB78,P29375,Q8IUF8	3
Heparan sulfate heparin hs gag metabolism	0.7957238028491959	1.0268218477896418	0.3045043597454964	1.0	0.8644058943751386	4	P54802	1
Regulation of hmox1 expression and activity	0.363735391433874	1.0255909537243395	0.3050844333088724	1.0	0.8644058943751386	44	Q99436,P49721,P60900,P28074,P09601	5
Extracellular matrix organization	0.4081944180679361	1.0235562264675897	0.3060449296740546	1.0	0.8653467518709923	27	O75718,O15460,P13674,O14936	4
Iron uptake and transport	0.4426144281762496	1.0123854845746645	0.3113537759285274	1.0	0.8731856404349944	17	Q93050,P09601,P30519	3
Antigen processing cross presentation	0.3559304287011955	1.0043570149247063	0.3152065612026271	1.0	0.8768473429818536	49	P20618,Q9UIQ6,Q99436,P49721,P60900,P28072,P28074,P10321	8
Mrna editing	0.7347840870452254	0.9996777891083088	0.317466464190101	1.0	0.8795801231182477	2	P55265	1
Signaling by notch4	0.3657496035697137	0.995158118066266	0.3196593679180819	1.0	0.8812227310199341	42	P20618,Q99436,P49721,P60900,P28074,P28072,Q06330	7
Beta oxidation of very long chain fatty acids	0.7835885495607502	0.9814082304906284	0.3263914690264502	1.0	0.8864802954956007	4	O75521,Q15067	2
Interleukin 1 family signaling	0.3617489318356813	0.980303773916879	0.3269361924038585	1.0	0.8864802954956007	43	P20618,P05067,Q99436,P49721,P60900,P28072,P28074,Q13501	8
Anchoring of the basal body to the plasma membrane	0.3881389396663333	0.975150317784302	0.3294857021743258	1.0	0.8864802954956007	31	O75935,P53350,Q9H6D7,O95684	4
N glycan trimming in the er and calnexin calreticulin cycle	0.4492023022720501	0.9736317508319056	0.3302394154866181	1.0	0.8864802954956007	15	Q13724	1
G alpha i signalling events	0.4151947319478867	0.9703956833502018	0.3318492995121609	1.0	0.8864802954956007	22	P07602,P16220,O43865,Q9NRV9	4
Recruitment of mitotic centrosome proteins and complexes	0.3871901455391852	0.967179292914086	0.3334544118884315	1.0	0.8864802954956007	31	O75935,P53350,Q9H6D7,O95684	4
Diseases of carbohydrate metabolism	0.5067902196194919	0.9656741433812852	0.3342072617869243	1.0	0.8864802954956007	9	P15586,P54802,P10253	3
Flt3 signaling in disease	0.5719493266662846	0.9622880075174638	0.3359049513815613	1.0	0.8864802954956007	6	Q92614,P62993,Q01082	3
Rhobtb2 gtpase cycle	0.4259292735752809	0.9583843716311116	0.3378689729600235	1.0	0.8864802954956007	19	P62995,Q9NYL9,Q12792,O43396,P38159	5
Degradation of axin	0.3752865194475673	0.9574897770045958	0.3383201038909456	1.0	0.8864802954956007	35	P20618,Q99436,P49721,P60900,P28074,P28072	6
Regulation of runx3 expression and activity	0.3752865194475673	0.9574897770045958	0.3383201038909456	1.0	0.8864802954956007	35	P20618,Q99436,P49721,P60900,P28074,P28072	6
Transcriptional activation of mitochondrial biogenesis	0.4607448271809117	0.9553095101869136	0.3394211995679601	1.0	0.8864802954956007	13	P16220,P48735,P06576,O00411	4
Asymmetric localization of pcp proteins	0.3722700078769668	0.94420632164355	0.3450642254071474	1.0	0.8864802954956007	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Hedgehog ligand biogenesis	0.3661879573535131	0.9372058733079964	0.3486526692063774	1.0	0.8915850965451613	39	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Nicotinamide salvaging	0.7978121727999414	0.9338329966781462	0.3503900457835094	1.0	0.8915850965451613	3	Q9BQG2	1
Nicotinate metabolism	0.7978121727999414	0.9338329966781462	0.3503900457835094	1.0	0.8915850965451613	3	Q9BQG2	1
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol	0.7191431485889143	0.9319002378999988	0.3513880846743336	1.0	0.8915850965451613	2	P22307	1
Beta oxidation of pristanoyl coa	0.7191431485889143	0.9319002378999988	0.3513880846743336	1.0	0.8915850965451613	2	P22307	1
Transcriptional regulation by e2f6	0.5632597467401401	0.9232483912435276	0.3558777759530169	1.0	0.8926037829759456	6	Q13185,Q969R5	2
Cobalamin cbl vitamin b12 transport and metabolism	0.7930422389137275	0.9159921956508018	0.3596709882627538	1.0	0.8960176007677888	3	Q99707	1
Defects in cobalamin b12 metabolism	0.7930422389137275	0.9159921956508018	0.3596709882627538	1.0	0.8960176007677888	3	Q99707	1
G1 s dna damage checkpoints	0.3689558727133782	0.9144331513370076	0.3604892889073021	1.0	0.8960176007677888	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Stabilization of p53	0.3689558727133782	0.9144331513370076	0.3604892889073021	1.0	0.8960176007677888	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Sumoylation of chromatin organization proteins	0.3711991256935872	0.9091425891850532	0.3632748641367418	1.0	0.896450896990188	34	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P45973,P37198,Q969R5,Q9HC52,Q8N1F7,O75925	14
Sumoylation of rna binding proteins	0.3832170483301484	0.9033372811571964	0.3663469158920582	1.0	0.896450896990188	30	Q96EE3,P12270,P07910,P57740,Q12769,P61978,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q9HC52,Q8N1F7	13
Signaling by notch3	0.5409556023559672	0.8994311456611482	0.3684230556817638	1.0	0.896450896990188	7	Q06330	1
Mecp2 regulates transcription of neuronal ligands	0.7609829460171845	0.8975005828985056	0.3694518625084471	1.0	0.896450896990188	4	Q96ST3	1
Complex i biogenesis	0.3738364177905143	0.8867939993275757	0.375189818898747	1.0	0.8986449827351275	32	O95298,Q9NPL8,Q7L592,Q9BQ95,Q9Y6M9,O75306,O43674,O96000,O75438,O43676,O75489,P03886	12
Cross presentation of soluble exogenous antigens endosomes	0.3654336996414128	0.882797103526857	0.3773459057352917	1.0	0.8986449827351275	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Runx1 regulates transcription of genes involved in differentiation of hscs	0.360201194197115	0.8815574043704351	0.3780161983080554	1.0	0.8986449827351275	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Sting mediated induction of host immune responses	0.553926876851464	0.8814740660668001	0.3780612847654812	1.0	0.8986449827351275	6	P19474	1
The role of gtse1 in g2 m progression after g2 checkpoint	0.3439630829141486	0.8814338079732428	0.3780830657907794	1.0	0.8986449827351275	47	Q99436,P49721,P60900,P28074,P28072	5
Immunoregulatory interactions between a lymphoid and a non lymphoid cell	0.652022082113352	0.8738345011495645	0.3822083886086327	1.0	0.8986449827351275	5	P10321,Q5KU26	2
Endosomal vacuolar pathway	0.7538929056536121	0.8714058525765743	0.3835325913345471	1.0	0.8986449827351275	4	Q9UIQ6,P10321	2
Hedgehog on state	0.3589227247212351	0.8696778774698591	0.3844764652482886	1.0	0.8986449827351275	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Regulation of ras by gaps	0.3639678707698118	0.8696347991569287	0.3845000141048154	1.0	0.8986449827351275	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Degradation of dvl	0.3639678707698118	0.8696347991569287	0.3845000141048154	1.0	0.8986449827351275	36	P20618,Q99436,P49721,P60900,P28074,P28072	6
Cytoprotection by hmox1	0.3407403084919098	0.86949485543766	0.3845765207413594	1.0	0.8986449827351275	61	Q99436,P49721,P60900,P30519,P28072,P28074,P09601	7
Mitotic g2 g2 m phases	0.3240469842085188	0.8615122117240285	0.3889559983370632	1.0	0.8986449827351275	84	P20618,P53350,O95684,Q9UL46,Q99436,P49721,O43805,P60900,Q9H6D7,P30307,O75935,P28074,P28072	13
Signaling by notch	0.3408079498887171	0.8601824944611648	0.3896884527909168	1.0	0.8988291448795518	58	P28074,P67809,P20618,Q9UL46,Q99436,P49721,P60900,P16220,P28072,Q06330	10
Downstream signaling events of b cell receptor bcr	0.3570251589577277	0.8520503468323494	0.3941861489375844	1.0	0.9031519585475104	39	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Degradation of gli1 by the proteasome	0.3558922678223605	0.8415294818093978	0.4000513759833648	1.0	0.9135501570963406	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Regulation of runx2 expression and activity	0.3534541645593667	0.8364605977857529	0.4028958343585589	1.0	0.9154361647117436	40	P20618,Q99436,P49721,P60900,P28074,P28072	6
Inla mediated entry of listeria monocytogenes into host cells	0.6967018021081289	0.83626879447878	0.4030037042830625	1.0	0.9154361647117436	2	O60716	1
Mecp2 regulates neuronal receptors and channels	0.4992018421755586	0.8318713523522826	0.4054815635670281	1.0	0.9154361647117436	8	Q96ST3	1
Regulation of pten stability and activity	0.3563471925062054	0.8294310853659711	0.4068605176496638	1.0	0.9154361647117436	38	P20618,Q99436,P49721,P60900,P28074,P28072	6
Abc family proteins mediated transport	0.3386156407313601	0.8257357575541319	0.4089540035604575	1.0	0.916864095785507	49	Q99436,P49721,P08183,P60900,P28074	5
G beta gamma signalling through pi3kgamma	0.6909214552873189	0.8120012935905472	0.4167908892232144	1.0	0.9179491155356986	2	P61586	1
Sumoylation of ubiquitinylation proteins	0.3811463258652443	0.8106259165411311	0.4175805290513921	1.0	0.9179491155356986	27	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q8N1F7,O75925	11
Pregnenolone biosynthesis	0.7361763368727137	0.8067615303082406	0.4198038867520357	1.0	0.9179491155356986	4	O95772	1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1	0.634918653075641	0.8053056031042365	0.4206433492396702	1.0	0.9179491155356986	5	P35222,Q99626,P61009	3
Incretin synthesis secretion and inactivation	0.634918653075641	0.8053056031042365	0.4206433492396702	1.0	0.9179491155356986	5	P35222,Q99626,P61009	3
G protein mediated events	0.447818012210925	0.7976600893039366	0.42506777033699	1.0	0.9207615770245634	11	P16220	1
Abc transporter disorders	0.3473183341126407	0.7973022746168972	0.4252754996279029	1.0	0.9207615770245634	41	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Defective cftr causes cystic fibrosis	0.3473183341126405	0.7973022746168972	0.4252754996279029	1.0	0.9207615770245634	41	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Tgf beta receptor signaling in emt epithelial to mesenchymal transition	0.7322218441646866	0.7924542371499319	0.4280958652874129	1.0	0.921454777498238	4	Q9Y624,P62942,P61586	3
Tryptophan catabolism	0.686161169670185	0.7921426427724231	0.4282775081574443	1.0	0.921454777498238	2	Q6YP21	1
Recruitment of numa to mitotic centrosomes	0.3565376104561077	0.7910041863447295	0.4289415485667178	1.0	0.921454777498238	35	O75935,P53350,Q9H6D7,O95684	4
O linked glycosylation of mucins	0.7300689823315718	0.7846855761036068	0.4326379417296002	1.0	0.9250659095677944	4	O43505	1
Signaling by flt3 fusion proteins	0.6293667390115677	0.7832452406818314	0.4334831127775633	1.0	0.925436040766984	5	Q92614,P62993,Q01082	3
Role of phospholipids in phagocytosis	0.752262283364898	0.7661562895126554	0.4435833132114406	1.0	0.931977492316029	3	Q8IV08	1
Clec7a dectin 1 signaling	0.341737456716937	0.7637382883595405	0.4450232188720062	1.0	0.931977492316029	42	P20618,O43865,Q99436,P49721,P60900,P28074,P28072	7
Hdr through single strand annealing ssa	0.4203089947935287	0.7548598149073509	0.4503330995577801	1.0	0.931977492316029	14	Q9UQ84	1
Homologous dna pairing and strand exchange	0.4203089947935287	0.7548598149073509	0.4503330995577801	1.0	0.931977492316029	14	Q9UQ84	1
Tnfr2 non canonical nf kb pathway	0.346078806763564	0.7505483740415656	0.4529245007767009	1.0	0.931977492316029	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Dectin 1 mediated noncanonical nf kb signaling	0.346078806763564	0.7505483740415656	0.4529245007767009	1.0	0.931977492316029	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Cell cycle checkpoints	0.3168803676496696	0.7489833194479565	0.4538672592996888	1.0	0.931977492316029	120	Q9UJX3,P30307,P28072,Q96EE3,Q96DE5,P53350,Q14566,Q8NFH4,Q9UJX6,Q9UQ84,Q9HBM1,Q14191,O60921,P20618,Q99436,P33991,Q9UL46,P49721,P60900,P28074,Q9UJX4	21
Syndecan interactions	0.6206088430879273	0.7486569753791138	0.45406398199312	1.0	0.931977492316029	5	Q9Y296,O14936	2
Non integrin membrane ecm interactions	0.6206088430879273	0.7486569753791138	0.45406398199312	1.0	0.931977492316029	5	Q9Y296,O14936	2
Activation of the pre replicative complex	0.3920404874798178	0.7481514586281658	0.4543688062434059	1.0	0.931977492316029	20	Q14566	1
Unfolded protein response upr	0.3457758726391245	0.7477456954515845	0.4546135629757075	1.0	0.931977492316029	39	Q9Y3B2,P43307,Q9NWM8,O14773	4
Bile acid and bile salt metabolism	0.7186117727118049	0.7435986432268102	0.4571193243037177	1.0	0.931977492316029	4	P22307,Q96SU4,P51659	3
Synthesis of bile acids and bile salts	0.7186117727118049	0.7435986432268102	0.4571193243037177	1.0	0.931977492316029	4	P22307,Q96SU4,P51659	3
Regulation of plk1 activity at g2 m transition	0.3509948874145541	0.7419462188512015	0.4581199211640361	1.0	0.931977492316029	35	O75935,P53350,Q9H6D7,O95684	4
Disorders of transmembrane transporters	0.322738965276479	0.7414658955938264	0.4584110028790817	1.0	0.931977492316029	74	Q96EE3,P20618,P53985,Q9BTX1,Q8NFH4,Q9UL46,Q99436,P49721,P60900,P28074,Q9UBV2,P28072	12
Mapk family signaling cascades	0.3133506828221445	0.7391850761487012	0.4597946217279314	1.0	0.931977492316029	85	P30086,Q99436,P49721,O60725,P60900,P07196,P28074,P28072,P04792	9
Ion transport by p type atpases	0.462497754095773	0.7384479799394061	0.4602422674548605	1.0	0.931977492316029	9	Q9HD20	1
Cyclin a cdk2 associated events at s phase entry	0.3445031098400483	0.7359752186453803	0.4617457791755259	1.0	0.931977492316029	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Scf skp2 mediated degradation of p27 p21	0.3445031098400483	0.7359752186453803	0.4617457791755259	1.0	0.931977492316029	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Regulation of ifng signaling	0.6173584713311862	0.7358907015436889	0.4617972164907973	1.0	0.931977492316029	5	O75925	1
Synthesis of dna	0.3162188268812507	0.7282418327199451	0.4664655622279534	1.0	0.9326688453310452	81	P20618,Q96DE5,Q14566,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,P60900,P28074,P33991,P28072	12
Metabolism of cofactors	0.6152740067624807	0.7277249985715913	0.4667819443538592	1.0	0.9326688453310452	5	O75874,P00374	2
Negative regulation of notch4 signaling	0.3430128667905528	0.7222040232842957	0.4701690501216506	1.0	0.9328510269238316	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Dex h box helicases activate type i ifn and inflammatory cytokines production	0.6664399863991908	0.7112214933756302	0.4769469915685433	1.0	0.9328510269238316	2	Q9H2U1	1
Degradation of beta catenin by the destruction complex	0.3271031934703118	0.7109407316998749	0.4771209639661022	1.0	0.9328510269238316	46	P28074,P60900,Q99436,P49721	4
Biological oxidations	0.3315404614074759	0.7072550337689858	0.4794080038809138	1.0	0.9328510269238316	44	O15217,P30837,Q16850,Q99707,P78417,Q9NUJ1,P07099,Q8TB61,P05091	9
Trna modification in the nucleus and cytosol	0.4562333971841125	0.7067874469477854	0.4796985766877766	1.0	0.9328510269238316	9	Q08J23	1
Mitotic g1 phase and g1 s transition	0.3204070657006397	0.7064656486994231	0.4798986077963749	1.0	0.9328510269238316	73	Q14566,Q99436,P49721,P60900,P28074,P33991,P28072	7
Integration of provirus	0.5099954865659844	0.6881484058972479	0.4913593304216803	1.0	0.934628686823087	6	P12956	1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.4684537462777606	0.683763244472755	0.4941246797437961	1.0	0.934628686823087	8	P09601	1
Ksrp khsrp binds and destabilizes mrna	0.4134265993844001	0.678724778821667	0.4973122628421618	1.0	0.9347851086344284	13	Q9Y3B2	1
Mapk6 mapk4 signaling	0.3241440426151279	0.678074843748235	0.4977242400210437	1.0	0.9347851086344284	48	Q99436,P49721,P60900,P28074,P04792	5
Fcgr3a mediated il10 synthesis	0.4667281921439201	0.6755620285278678	0.4993187566452641	1.0	0.9347851086344284	8	P16220,O43865	2
Synthesis of pg	0.7265752741696299	0.6749293443310289	0.4997206559888854	1.0	0.9347851086344284	3	Q8IV08	1
Clathrin mediated endocytosis	0.3238079187287358	0.67222441870846	0.5014408377990036	1.0	0.9347851086344284	53	Q7L5N1,Q9UHD9,O14964,P98164,O14976,O43493,Q9UKS6,Q14108,P61201,P11717,P01130	11
Calnexin calreticulin cycle	0.4657580919931725	0.6709575849064291	0.5022475503184092	1.0	0.9347851086344284	8	Q9GZP9,Q14697,Q9NYU2,P27824,P27797,Q9UBV2,P30101	7
Antigen processing ubiquitination proteasome degradation	0.3103693523312026	0.6667173764837597	0.5049526773416293	1.0	0.9347851086344284	82	P20618,P19474,P55786,Q9UJX3,Q9UL46,Q9UIQ6,Q99436,P49721,Q9UJX6,Q9UBS8,P60900,P28074,P28072	13
Dna replication	0.3074982114052027	0.665036504345307	0.5060271449820308	1.0	0.9347851086344284	85	P20618,Q96DE5,Q14566,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,P60900,P28074,P33991,P28072	12
Dag and ip3 signaling	0.4636153550489125	0.6608037629983402	0.508738169278937	1.0	0.9347851086344284	8	P16220	1
Assembly of the hiv virion	0.7222458353380116	0.6598501873432784	0.5093499730131796	1.0	0.9347851086344284	3	Q9NZ09	1
Listeria monocytogenes entry into host cells	0.4624753341849592	0.6554109347647269	0.5122032131198135	1.0	0.9372845896459862	8	Q9NWH9,P62993,O14964,O60716	4
Cyclin a b1 b2 associated events during g2 m transition	0.4454899872657067	0.6529078015228249	0.5138157191389081	1.0	0.9372845896459862	9	P53350,P30307	2
Cdt1 association with the cdc6 orc origin complex	0.3354670275659499	0.6526830258950942	0.5139606476240217	1.0	0.9372845896459862	39	P20618,Q99436,P49721,P60900,P28074,P28072	6
Hedgehog off state	0.3215532052932741	0.6517110112263979	0.5145876178448552	1.0	0.9372845896459862	48	P28074,P60900,Q99436,P49721	4
Fceri mediated nf kb activation	0.333257431975843	0.6475144489080402	0.5172990462104012	1.0	0.9408101217382514	40	P20618,Q99436,P49721,P60900,P28074,P28072	6
Rnd3 gtpase cycle	0.3958135192149189	0.6437090799540144	0.5197641008477083	1.0	0.9408101217382514	15	O75976,P38159,O43396,Q9NYL9	4
Antigen activates b cell receptor bcr leading to generation of second messengers	0.715124269911128	0.6352529049137806	0.5252634836322088	1.0	0.943888339822131	3	O43865	1
Atf4 activates genes in response to endoplasmic reticulum stress	0.4112561858761528	0.6299927591494073	0.5286993216841815	1.0	0.943888339822131	12	Q9Y3B2	1
Transport of mature mrnas derived from intronless transcripts	0.3358513534852793	0.6297548476154933	0.5288549914752911	1.0	0.943888339822131	37	Q96EE3,P12270,Q6UN15,Q9UKF6,P57740,Q86V81,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,Q92797,P37198,Q8N1F7	14
Heme signaling	0.4962451722751533	0.629257207986601	0.5291806814398585	1.0	0.943888339822131	6	P09601	1
Chylomicron assembly	0.6426385583135052	0.616949920864799	0.5372677579616933	1.0	0.9546034873719376	2	Q9Y6B6	1
Lysosome vesicle biogenesis	0.4019396409272796	0.6130826611503298	0.5398216842934143	1.0	0.9554427497069812	13	P15586,O14964	2
Pcp ce pathway	0.3167702129376692	0.606838693953862	0.5439579664817296	1.0	0.9590654543474284	46	P28074,P60900,Q99436,P49721	4
Formyl peptide receptors bind formyl peptides and many other ligands	0.7056685250922297	0.6030140212803972	0.5464993616266023	1.0	0.9607067847802933	3	Q9NRV9	1
Metabolism of polyamines	0.3312656242305007	0.6007719656749418	0.5479918787692006	1.0	0.9607067847802933	38	P28074,P60900,Q99436,P49721	4
Cellular response to hypoxia	0.3325444701928771	0.6001934876826537	0.5483772932732829	1.0	0.9607067847802933	37	P20618,Q99436,P49721,P60900,P28074,P28072	6
Regulation of pyruvate dehydrogenase pdh complex	0.4881155073515785	0.5949281611277949	0.5518914922165183	1.0	0.9625815511675044	6	P09622,Q15120,P11177,Q8NCN5	4
Ethanol oxidation	0.7031495524320397	0.5945107873410574	0.5521705294447714	1.0	0.9625815511675044	3	P30837	1
Fgfr1 mutant receptor activation	0.4335992617793698	0.5940090372727038	0.5525060684946734	1.0	0.9625815511675044	9	Q92614,O15164,O95684	3
Class i peroxisomal membrane protein import	0.4733118683987892	0.5933564405770113	0.5529426339676804	1.0	0.9625815511675044	7	Q8NBU5	1
Polo like kinase mediated events	0.7008206802727874	0.5866823035708867	0.5574170950512114	1.0	0.9638794541375876	3	P53350	1
Signaling by cytosolic fgfr1 fusion mutants	0.4471723368593674	0.5837199440736235	0.559408746777184	1.0	0.9638794541375876	8	Q92614,O15164,O95684	3
Regulation of kit signaling	0.6998841179661561	0.5835431373503925	0.5595277264825762	1.0	0.9638794541375876	3	P07947	1
Piwi interacting rna pirna biogenesis	0.4190099212995951	0.5817018392780553	0.5607675324247026	1.0	0.9638794541375876	10	Q9Y2W6,P52434,Q8N2A8,P19388	4
Slc transporter disorders	0.3340117183959427	0.5771641482841359	0.5638285734772266	1.0	0.9656616239777874	33	Q96EE3,P12270,O00400,P57740,Q12769,P53985,Q99567,P08195,Q8NFH4,P78406,Q9BTX1,Q9NRG9,P37198,Q8N1F7	14
Arachidonic acid metabolism	0.4428204878194922	0.5635968853469312	0.5730285070153847	1.0	0.9702975605743446	8	Q14914,Q8N8N7	2
Activation of kainate receptors upon glutamate binding	0.6911564625850417	0.5545478591417322	0.5792039615798976	1.0	0.9735447757973996	3	Q15334,Q92796	2
Thromboxane signalling through tp receptor	0.6911564625850298	0.5545478591416936	0.579203961579924	1.0	0.9735447757973996	3	Q13685,Q14344	2
Class i mhc mediated antigen processing presentation	0.2894373622228901	0.5502274500411518	0.5821633781476883	1.0	0.9762835586394693	104	P20618,Q9NZ08,P19474,P55786,Q9UJX3,Q9UL46,Q9UIQ6,Q99436,P49721,Q9UJX6,Q9UBS8,P60900,P53992,P28074,P10321,P28072	16
Coenzyme a biosynthesis	0.6205372322339414	0.5334447064676093	0.5937257772836968	1.0	0.9796956264383976	2	Q13057	1
C type lectin receptors clrs	0.3090143542531098	0.5271385650606851	0.5980973674786212	1.0	0.9796956264383976	47	P20618,O43865,Q99436,P49721,P60900,P28074,P28072	7
Mitochondrial translation	0.3097706606525643	0.5263850631424748	0.5986206916955608	1.0	0.9796956264383976	55	Q9NQ50,Q9BYD6,Q8TAE8,Q9NYK5,Q7Z7F7,P82663,P82933,Q9H9J2,Q92552,Q9NRX2,Q96RP9,Q96DV4,Q9Y3D3,Q92665,Q8N5N7,Q15070,Q96EL3,P52815,Q13084,Q9Y2Q9,Q96A35,P82673,P82912,Q9H2W6	24
Methionine salvage pathway	0.6824328899069116	0.5260532974716037	0.5988511763396613	1.0	0.9796956264383976	3	Q13126	1
Nuclear envelope breakdown	0.3214933201474527	0.5252496958063692	0.5994096221491203	1.0	0.9796956264383976	39	Q96EE3,P57740,Q12769,Q99567,P53350,Q8NFH4,Q9BTX1,Q8NC56,P37198,P50402,Q8N1F7,P42166,P02545	13
Rna polymerase ii transcribes snrna genes	0.3595767428023064	0.5251937459051427	0.5994485121195807	1.0	0.9796956264383976	20	O00267,Q9NQG5,P52434,Q96SY0,P19388,Q9BXP5,Q96CB8	7
Cargo concentration in the er	0.3805321436250252	0.5216325612688016	0.6019261876921917	1.0	0.9796956264383976	14	Q9Y6B6,P53634,Q12907,Q96PC5,Q13190,P53992	6
Ire1alpha activates chaperones	0.3514110795753642	0.5189483309236937	0.6037967730197222	1.0	0.9796956264383976	23	Q9NWM8,O14773	2
Trans golgi network vesicle budding	0.324367156962277	0.5091219592406044	0.6106667405610393	1.0	0.9796956264383976	35	O14964,P05067,Q9H3P7,P15586,O14976,Q14671,O75976,P11717	8
Beta catenin independent wnt signaling	0.3076260492780833	0.5077973108281503	0.6115954959022969	1.0	0.9796956264383976	50	P28074,P60900,Q99436,P49721	4
Nephrin family interactions	0.4521508502868233	0.5023498677896447	0.6154214366813888	1.0	0.9796956264383976	7	Q13813,P12814,O14936,O43707	4
Inlb mediated entry of listeria monocytogenes into host cell	0.4649570850591999	0.4995427519774255	0.6173970765966796	1.0	0.9796956264383976	6	Q9NWH9,O14964	2
Mitochondrial fatty acid beta oxidation of saturated fatty acids	0.4635552882443143	0.4938985311989423	0.621377841948225	1.0	0.9796956264383976	6	Q16836	1
Neutrophil degranulation	0.3344277302547876	0.4899466974348705	0.6241716175411787	1.0	0.9796956264383976	169	Q8WVQ1,P14174,P30519,Q96JM3,Q92820,P06280,P15586,P04066,O00264,Q9NQX7,Q9BTY2,P10321,P20618,O15260,P10619,Q13510,Q99436,P10253,P42785,P17900,P07602,O00560,O00584,P61916,Q93050,P12956	26
Class b 2 secretin family receptors	0.6062563753825301	0.4819091797262089	0.6298704647098705	1.0	0.9796956264383976	2	Q9UBI6	1
Transcriptional regulation by runx2	0.3032780409383199	0.4678939832305504	0.6398604064183919	1.0	0.9796956264383976	48	Q96PK6,P20618,Q99436,P49721,P60900,P28074,P28072	7
Epha mediated growth cone collapse	0.4214069163367895	0.4666533159894453	0.6407479351344565	1.0	0.9796956264383976	8	Q15375	1
Sumoylation of sumoylation proteins	0.3380581399415482	0.4619546563545193	0.644113837583135	1.0	0.9796956264383976	26	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q8N1F7	10
Regulation of glucokinase by glucokinase regulatory protein	0.3380581399415482	0.4619546563545193	0.644113837583135	1.0	0.9796956264383976	26	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q8N1F7	10
Interaction between l1 and ankyrins	0.6612244897959194	0.4590016019256051	0.6462330157188025	1.0	0.9796956264383976	3	Q13813,Q12955	2
Sialic acid metabolism	0.6340915320990999	0.4589193053429012	0.6462921148298335	1.0	0.9796956264383976	4	P10619	1
2 ltr circle formation	0.5430991301943979	0.4588111650348755	0.6463697763211513	1.0	0.9796956264383976	5	P12956	1
Signaling by hedgehog	0.3029288871778876	0.4561014143047388	0.6483170532037006	1.0	0.9796956264383976	54	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Regulation of mecp2 expression and activity	0.3934704838291317	0.4536053605299403	0.6501128945596668	1.0	0.9796956264383976	10	Q96ST3	1
Vxpx cargo targeting to cilium	0.403919782154124	0.4514864743927067	0.6516389711754473	1.0	0.9796956264383976	9	Q96KP1	1
Perk regulates gene expression	0.3679374716173592	0.4505906962517858	0.6522845733529161	1.0	0.9796956264383976	14	Q9Y3B2	1
Sulfur amino acid metabolism	0.3928011225146784	0.4503306257661769	0.652472059307613	1.0	0.9796956264383976	10	Q13126,Q99707	2
Organic anion transporters	0.5940156409384645	0.4394350488490423	0.6603463351971821	1.0	0.9796956264383976	2	Q9UBX3	1
Viral messenger rna synthesis	0.3168282699715586	0.4380143151638884	0.6613759063139151	1.0	0.9796956264383976	34	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P52434,P37198,P19388,Q8N1F7,P19387	13
S phase	0.2846643241914287	0.4339984487432377	0.6642895675311413	1.0	0.9796956264383976	90	P20618,Q96DE5,Q14566,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,Q9UJX4,Q7Z5K2,P60900,P28074,P33991,P28072	14
Cellular response to chemical stress	0.2970088554953311	0.4301192362263546	0.6671089077402554	1.0	0.9796956264383976	72	Q99436,P49721,P60900,P30519,P28072,P28074,P09601	7
Miro gtpase cycle	0.651020408163259	0.4279657106099538	0.668676085017156	1.0	0.9796956264383976	3	Q8IXI1,Q8IWA4	2
Citric acid cycle tca cycle	0.3478744273454326	0.4226129208451559	0.6725776979679678	1.0	0.9796956264383976	18	P48735,Q13423	2
Regulation of tp53 activity through phosphorylation	0.3302878148988937	0.4185949022585299	0.6755122158088196	1.0	0.9796956264383976	27	Q9UQ84,Q92804	2
Met activates ptpn11	0.6477622200813066	0.418235704678588	0.6757747931203755	1.0	0.9796956264383976	3	Q9NWH9	1
Cell death signalling via nrage nrif and nade	0.3918206753359664	0.3957605618275735	0.6922816734359099	1.0	0.9888712285490124	9	Q13501	1
Transport of the slbp dependant mature mrna	0.3193013345423049	0.38565227646577	0.6997542114868542	1.0	0.9923393915730157	30	Q96EE3,P12270,P57740,Q86V81,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q8N1F7	11
Inflammasomes	0.6057067281735631	0.3734719231419657	0.708797238209514	1.0	0.9942130235214152	4	P09601	1
Purinergic signaling in leishmaniasis infection	0.6057067281735631	0.3734719231419657	0.708797238209514	1.0	0.9942130235214152	4	P09601	1
The nlrp3 inflammasome	0.6057067281735629	0.3734719231419651	0.7087972382095145	1.0	0.9942130235214152	4	P09601	1
Dna damage recognition in gg ner	0.3485578709029467	0.3676496058544468	0.7131345212763371	1.0	0.9942130235214152	15	Q16531,P61201	2
Miscellaneous transport and binding events	0.5139665555083297	0.3608538778411682	0.7182086838140791	1.0	0.9942130235214152	5	Q8N4V1	1
Sensory processing of sound by outer hair cells of the cochlea	0.3641790355850698	0.3563680662138321	0.7215649410864868	1.0	0.9942130235214152	11	Q12792	1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.3952468818347575	0.3540753410850816	0.7232824215141382	1.0	0.9942130235214152	8	O95628	1
Beta oxidation of decanoyl coa to octanoyl coa coa	0.5115483026261349	0.3530809264776002	0.7240277716528298	1.0	0.9942130235214152	5	Q16836	1
Beta oxidation of octanoyl coa to hexanoyl coa	0.5115483026261349	0.3530809264776002	0.7240277716528298	1.0	0.9942130235214152	5	Q16836	1
Formation of tc ner pre incision complex	0.3183733716821793	0.3448833618077503	0.7301820594309112	1.0	0.9942130235214152	28	Q16531,Q93009,Q7L5N1,P61201	4
Extra nuclear estrogen signaling	0.3614719511608399	0.3432756764145301	0.7313910777155725	1.0	0.9942130235214152	11	P04792	1
Cholesterol biosynthesis	0.3481723399365455	0.343181888691616	0.7314616289806735	1.0	0.9942130235214152	14	Q16850	1
Separation of sister chromatids	0.2746569362844656	0.3418032595446225	0.7324989564135116	1.0	0.9942130235214152	93	Q96EE3,P20618,Q96DE5,P53350,Q8NFH4,Q9UJX3,Q9UL46,Q9UJX6,Q99436,P49721,P60900,Q9HBM1,P28074,Q9UJX4,P28072	15
Dna strand elongation	0.317263153318058	0.336677228639558	0.7363602311204174	1.0	0.9942130235214152	28	Q14566	1
Sumoylation of transcription cofactors	0.3585922789708216	0.3294688112740783	0.7418013642001697	1.0	0.9959640672050472	11	O75925	1
Activation of nmda receptors and postsynaptic events	0.3242823695678364	0.3285853985905099	0.7424690860251935	1.0	0.9959640672050472	23	P16220,Q14168,P07196	3
O linked glycosylation	0.4201359167185127	0.328363881751385	0.7426365485277127	1.0	0.9959640672050472	6	O43505	1
Sensory processing of sound	0.3401032844354119	0.3213134805145723	0.7479728416420737	1.0	0.9959640672050472	15	Q12792	1
Tcr signaling	0.2905824062859644	0.3148454539453055	0.7528789981975501	1.0	0.9959640672050472	44	P28074,P60900,Q99436,P49721	4
Signaling by fgfr2	0.3234712146421761	0.3147903409122288	0.752920846018025	1.0	0.9959640672050472	22	P52597,P31943,P09651,P52272	4
Signaling by fgfr	0.3234712146421761	0.3147903409122288	0.752920846018025	1.0	0.9959640672050472	22	P52597,P31943,P09651,P52272	4
Synthesis secretion and deacylation of ghrelin	0.6108843537414981	0.3147649110549569	0.7529401553815935	1.0	0.9959640672050472	3	P67812,P61009	2
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip	0.6108843537414981	0.3147649110549569	0.7529401553815935	1.0	0.9959640672050472	3	P67812,P61009	2
Negative regulation of met activity	0.4044315990579387	0.3117531000582666	0.7552281695410479	1.0	0.998031851687162	7	Q9NWH9,O14964	2
Metabolism of fat soluble vitamins	0.4121998616871555	0.3003949567013833	0.7638759101300341	1.0	1.0	6	P01130,P98164	2
Transcriptional regulation by runx1	0.2869142862803916	0.2934373100809551	0.7691879106014865	1.0	1.0	63	P20618,Q9UBL3,Q9UL46,Q99436,P49721,Q96ST3,P60900,P28074,P28072	9
Cell cell junction organization	0.3801812389890394	0.2929380281497892	0.7695695209514379	1.0	1.0	8	Q8NI35,Q9Y624,O60716,P19022,P35222	5
Rhoa gtpase cycle	0.2922912977528593	0.278506223067691	0.780623788626966	1.0	1.0	40	O15173,Q9H0H5,Q8NBN3,Q07021,P27105,P49257,Q13190,P30519,P02786,O75955,Q96CS3,P42166	12
Atf6 atf6 alpha activates chaperones	0.5372322339340481	0.2666611781962547	0.7897300471288222	1.0	1.0	2	P27797	1
Atf6 atf6 alpha activates chaperone genes	0.5372322339340481	0.2666611781962547	0.7897300471288222	1.0	1.0	2	P27797	1
Glycogen storage diseases	0.5632101066175428	0.2587815764441299	0.7958037736516843	1.0	1.0	4	P10253	1
Hcmv late events	0.289758422707465	0.2395970981245255	0.8106426146200678	1.0	1.0	38	Q96EE3,P12270,P57740,Q12769,P61978,Q99567,Q8NFH4,P78406,Q9BTX1,Q99816,Q9UQN3,P37198,Q9NZ09,Q8N1F7	14
Rnd2 gtpase cycle	0.3296753367759293	0.232404266123936	0.8162240357424198	1.0	1.0	13	O43396,P38159	2
Neurexins and neuroligins	0.3632259615053727	0.2280389043747797	0.8196159958837519	1.0	1.0	8	Q14168	1
Integrin cell surface interactions	0.4690265486725586	0.2269548510649602	0.8204588497099643	1.0	1.0	5	Q08722,P06756,Q9Y624,P35613	4
Interactions of vpr with host cellular proteins	0.2901709832649559	0.2188356128352412	0.8267781041355047	1.0	1.0	33	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P17096,P37198,Q8N1F7	11
Depolymerisation of the nuclear lamina	0.3501220241228413	0.2185160263986625	0.8270270727545301	1.0	1.0	9	P50402,P42166,P02545	3
Activated notch1 transmits signal to the nucleus	0.5144508670520286	0.2102181771794836	0.8334973931930403	1.0	1.0	2	Q92542	1
Ion channel transport	0.3029237807164259	0.20347268411316	0.8387655940161816	1.0	1.0	25	Q9Y487,Q9C0H2,Q9HD20,P27105,P05026,P51790,Q93050,Q9NQ11,Q12797	9
Translation of sars cov 2 structural proteins	0.3167221770465301	0.2002263228174049	0.8413035813607914	1.0	1.0	15	Q10472,Q13724	2
Signal amplification	0.370912806539512	0.1948224007585859	0.8455319850290428	1.0	1.0	7	P04899,P63096,Q14344,Q9UBI6,P08754,Q13685	6
Uptake and function of anthrax toxins	0.5018701122067334	0.1825011107209712	0.8551894827672428	1.0	1.0	2	Q8WUM4	1
P75ntr negatively regulates cell cycle via sc1	0.5005100306018367	0.1796543479296497	0.8574239352742172	1.0	1.0	2	Q13547	1
Rnd1 gtpase cycle	0.3212490857346292	0.1771556401624873	0.8593861384861337	1.0	1.0	12	O75976,O43396,P38159	3
Fc epsilon receptor fceri signaling	0.2729586369996281	0.1750740494789441	0.8610214488417305	1.0	1.0	49	P20618,O43865,Q99436,P49721,P60900,P28074,P28072	7
Signaling by ptk6	0.3363034527709721	0.1661306666520527	0.8680541209846615	1.0	1.0	9	P23246,Q07666,O75525	3
Processing of dna double strand break ends	0.3002224788865717	0.1653711805393511	0.8686518359398363	1.0	1.0	22	Q9UQ84	1
Signaling by retinoic acid	0.3343051361473989	0.1588621809619184	0.8737774574555874	1.0	1.0	9	P11177,Q9HBH5	2
Gaba synthesis release reuptake and degradation	0.4886093165589963	0.1559962129580449	0.8760360063001633	1.0	1.0	2	P51649	1
Eph ephrin mediated repulsion of cells	0.3143961544075407	0.1483936380348896	0.8820321206001167	1.0	1.0	12	Q15375,P07947	2
Anti inflammatory response favouring leishmania parasite infection	0.3058865578276966	0.1482929993225133	0.8821115400084127	1.0	1.0	15	P16220,O43865	2
Repression of wnt target genes	0.5346938775510165	0.1465996516351658	0.8834480286670523	1.0	1.0	3	Q13363,Q13547	2
Pi3k akt signaling in cancer	0.3376935127805118	0.1394602348025482	0.889086476843244	1.0	1.0	8	Q9NWH9,P16220	2
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids	0.5085956360143093	0.1394544805505783	0.8890910236424974	1.0	1.0	4	P42126	1
Adrenaline noradrenaline inhibits insulin secretion	0.5210884353741451	0.1237701553517121	0.901497262658846	1.0	1.0	3	P63096,Q9UBI6	2
Dissolution of fibrin clot	0.4688881332879973	0.121712767071531	0.9031265017551916	1.0	1.0	2	P35237	1
Platelet adhesion to exposed collagen	0.4685481128867853	0.1211748799490162	0.903552520378943	1.0	1.0	2	P07948	1
Met interacts with tns proteins	0.468548112886783	0.1211748799490125	0.9035525203789458	1.0	1.0	2	Q9NWH9	1
Met activates ptk2 signaling	0.468548112886783	0.1211748799490125	0.9035525203789458	1.0	1.0	2	Q9NWH9	1
Elastic fibre formation	0.4685481128867778	0.1211748799490044	0.9035525203789524	1.0	1.0	2	P06756	1
Laminin interactions	0.4685481128867778	0.1211748799490044	0.9035525203789524	1.0	1.0	2	P06756	1
Molecules associated with elastic fibres	0.4685481128867778	0.1211748799490044	0.9035525203789524	1.0	1.0	2	P06756	1
Signal regulatory protein family interactions	0.519387755102028	0.1210740068762142	0.90363241720301	1.0	1.0	3	Q08722,P62993	2
Abc transporters in lipid homeostasis	0.4678680720843418	0.1201044499549408	0.9044004073569694	1.0	1.0	2	P40855	1
Circadian clock	0.3085419623183557	0.1139054111429437	0.9093127760168196	1.0	1.0	11	P16220	1
Mrna splicing minor pathway	0.2794140278381272	0.1076267618706529	0.9142917673914328	1.0	1.0	31	Q13435,P67809,P52434,P62304,Q15427,Q9Y333,P19387,Q07955,P19388,Q16629,Q9Y3B4	11
Transcriptional regulation of granulopoiesis	0.3399078982859574	0.1030588756141442	0.9179162436767508	1.0	1.0	7	P16220	1
Sensory perception	0.2886676884934054	0.1004377544318853	0.9199967975898776	1.0	1.0	23	O14936,P98164,P29375,Q12792,P01130	5
Tcf dependent signaling in response to wnt	0.2655583091632878	0.0887977096813364	0.9292426779116696	1.0	1.0	56	P20618,Q9UL46,Q99436,P49721,P60900,P28074,P28072	7
Molybdenum cofactor biosynthesis	0.4948979591836698	0.086086980949549	0.931397272899288	1.0	1.0	3	Q9NZB8,Q9Y697	2
Constitutive signaling by aberrant pi3k in cancer	0.4052706429751471	0.08221872851292	0.9344727806662972	1.0	1.0	5	Q9NWH9	1
Carboxyterminal post translational modifications of tubulin	0.3336738168198799	0.0754201098426805	0.9398804594357404	1.0	1.0	6	Q9BVA1,Q13885,Q14166,P68371,P04350	5
Retrograde transport at the trans golgi network	0.2952852796022735	0.0743409208887725	0.9407391169354592	1.0	1.0	12	O60499,P11717	2
Traf6 mediated nf kb activation	0.4675897478480807	0.0730221783009024	0.94178846889009	1.0	1.0	4	Q7Z434	1
Attachment of gpi anchor to upar	0.4819727891156345	0.0704499562532239	0.9438355306491736	1.0	1.0	3	Q96S52,Q969N2	2
G alpha s signalling events	0.3972089857045606	0.0681305195368333	0.9456817357164562	1.0	1.0	5	P04899,P63096,Q9UBI6,Q9Y3E5	4
Glutamate and glutamine metabolism	0.3252724795640327	0.0659923295660296	0.947383932263422	1.0	1.0	7	O94925,P00367,P54886,Q96C36,P32322,P04181	6
Formation of incision complex in gg ner	0.2923539327571638	0.0638394844848772	0.9490980382918348	1.0	1.0	12	O75925	1
Alpha oxidation of phytanate	0.460700918679825	0.0638360759638603	0.949100752362217	1.0	1.0	4	Q9UJ83,O43808,P51648	3
Mitotic spindle checkpoint	0.2600831475027844	0.0620607822288612	0.9505144280143356	1.0	1.0	45	Q96EE3,Q96DE5,P53350,Q9UJX3,Q8NFH4,Q9UJX6,Q9HBM1,Q9UJX4	8
Sema4d mediated inhibition of cell attachment and migration	0.4697179578164303	0.057351081016824	0.9542655305128468	1.0	1.0	3	Q9NWH9	1
Mhc class ii antigen presentation	0.2595558915030771	0.0573001905902317	0.954306068535158	1.0	1.0	49	P33176,P53634,Q9H0H5,P10619,P53992,Q14807,O75935,Q99538	8
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1	0.4141448486909218	0.056702646393746	0.9547820658921864	1.0	1.0	2	Q13547	1
Nuclear import of rev protein	0.2731627556839068	0.0543044551617641	0.9566926000872892	1.0	1.0	30	Q96EE3,P12270,P57740,Q12769,Q99567,Q8NFH4,P78406,Q9BTX1,P37198,Q8N1F7	10
Sulfide oxidation to sulfate	0.410404624277458	0.0537054709946476	0.957169823871425	1.0	1.0	2	Q9UBX3	1
Association of tric cct with target proteins during biosynthesis	0.2813727328149062	0.0530210848125422	0.9577151080897276	1.0	1.0	18	P04062,P51784	2
Autophagy	0.2592362192659176	0.0508313710519682	0.9594598926971378	1.0	1.0	50	Q15388,P21796,Q9NZ09,Q9NS69,Q13501,P08670	6
Ptk6 regulates rho gtpases ras gtpase and map kinases	0.393063583815028	0.0418380421726284	0.9666278082819744	1.0	1.0	2	P61586	1
Signalling to ras	0.4488350882432513	0.0386757960475035	0.9691488709235252	1.0	1.0	3	P11233	1
Ion homeostasis	0.2908917333970864	0.0357732943983283	0.97146312741559	1.0	1.0	10	O43865,Q12797	2
Cardiac conduction	0.2908917333970864	0.0357732943983283	0.97146312741559	1.0	1.0	10	O43865,Q12797	2
P75 ntr receptor mediated signalling	0.2806405500269822	0.0354441085042383	0.9717256132908008	1.0	1.0	14	Q13501	1
Tak1 activates nfkb by phosphorylation and activation of ikks complex	0.4433114169563333	0.0344568033698271	0.9725128877940896	1.0	1.0	3	P05067	1
Ovarian tumor domain proteases	0.2995016124636648	0.0312165346609513	0.9750968535878968	1.0	1.0	8	Q96FW1	1
Activation of ppargc1a pgc 1alpha by phosphorylation	0.3702822169330267	0.0306716193595392	0.975531424979796	1.0	1.0	2	P54619	1
Activated tak1 mediates p38 mapk activation	0.3702822169330177	0.0306716193595356	0.9755314249797988	1.0	1.0	2	Q15750	1
Adp signalling through p2y purinoceptor 1	0.3702822169330156	0.0306716193595348	0.9755314249797996	1.0	1.0	2	Q9UBI6	1
P38mapk events	0.3702822169330133	0.0306716193595339	0.9755314249798002	1.0	1.0	2	P11233	1
Vitamin b5 pantothenate metabolism	0.4284892433855564	0.028063631285471	0.9776114006709888	1.0	1.0	4	Q9NRN7	1
Type i hemidesmosome assembly	0.3451207072424319	0.0228908288238079	0.9817373560187004	1.0	1.0	2	Q03001	1
Assembly of collagen fibrils and other multimeric structures	0.3451207072424319	0.0228908288238079	0.9817373560187004	1.0	1.0	2	Q03001	1
Ca2 pathway	0.4225927186117759	0.0227331212064759	0.981863155755078	1.0	1.0	4	P09471,P35222,Q9UBI6	3
Transcriptional regulation by mecp2	0.2769313868086301	0.0221027520962939	0.9823659911580428	1.0	1.0	14	Q96ST3	1
Aquaporin mediated transport	0.364533696392104	0.0207754116151911	0.983424812193974	1.0	1.0	5	P13861,Q99797,P10644,Q9UBI6	4
Glucagon like peptide 1 glp1 regulates insulin secretion	0.3645336963921042	0.0207754116151911	0.983424812193974	1.0	1.0	5	P13861,P10644,Q9UBI6,P46940	4
Regulation of ifna signaling	0.4129251700680257	0.0160293787041448	0.9872109538867228	1.0	1.0	3	P42224,Q06124	2
Slbp dependent processing of replication dependent histone pre mrnas	0.4112244897959238	0.01521522044675	0.9878604789072568	1.0	1.0	3	P62318,P62304	2
Postmitotic nuclear pore complex npc reformation	0.274050233279506	0.015142064719549	0.9879188420089522	1.0	1.0	22	Q96EE3,P57740,Q12769,Q9BTX1,Q8NFH4,Q8N1F7	6
Retrograde neurotrophin signalling	0.2873210633946797	0.0134033624985238	0.989305984197424	1.0	1.0	9	P53680,O95782,P50570,Q9UQ16,O94973,Q96CW1,P09496,P63010	8
Tp53 regulates transcription of cell cycle genes	0.2750207336198164	0.0128401660165075	0.9897553112847944	1.0	1.0	13	O95628	1
Ros and rns production in phagocytes	0.2913811944219204	0.0123219980593008	0.9901687167741736	1.0	1.0	8	Q93050	1
Neddylation	0.2581058758441317	0.0084941355441082	0.9932227418889984	1.0	1.0	66	Q7L5N1,P20618,Q99436,P49721,Q16531,P60900,P28074,P61201,P28072	9
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation	0.3908163265306044	0.0069780352659838	0.9944323785805798	1.0	1.0	3	P10809,P06748	2
Assembly of the orc complex at the origin of replication	0.2955396663261813	0.0058817488072567	0.99530707049481	1.0	1.0	6	O43913,Q9Y619,P52294,P16104,P62805	5
G alpha z signalling events	0.3970738346376333	0.0035893891679956	0.997136087949782	1.0	1.0	4	P04899,P63096,Q9UBI6	3
Adp signalling through p2y purinoceptor 12	0.3970738346376333	0.0035893891679956	0.997136087949782	1.0	1.0	4	P04899,P63096,Q9UBI6	3
Gaba b receptor activation	0.3970738346376333	0.0035893891679956	0.997136087949782	1.0	1.0	4	P04899,P63096,Q9UBI6	3
Gaba receptor activation	0.3970738346376333	0.0035893891679956	0.997136087949782	1.0	1.0	4	P04899,P63096,Q9UBI6	3