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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ca62ad06695b353327e6ac46a348b88d7e07c5bd9ac369942f208dd5d51f97da
+size 73548

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.327272727272727
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C240/C240_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.9414965986394572	2.0053118883361782	0.044929714676007	0.9202109435094772	0.1235567153590193	3	Q9H3G5,P10619	2
+Histidine acid phosphatase active site [IPR033379]	0.9156749404964328	1.7381201607635637	0.0821896431893343	0.991058456899552	0.1883512656422244	2	Q9NPH0	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.8586131283872194	1.51589495351218	0.1295459165749766	0.9995146861528376	0.2740394389086044	4	P21281	1
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.4472490534207723	0.3960258136791184	0.6920859852127281	1.0	0.7930151913895843	6	P68036,Q16763	2
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.4588435374149616	0.225951783369296	0.8212389217964713	1.0	0.8968392966996931	3	P00390,P09622	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K2", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE2T", "UMPS", "VRK1", "YES1"], "leading_proteins": ["ACP6", "ATP6V1B2", "CPVL", "CTSA", "DLD", "GSR", "UBE2L3", "UBE2S"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:d2bf8660feb735d3c5f91faaf82f745beabe132abe934aae4675d6a538114fb7
+size 69007

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	11	37	2.253009048203579	0.0242585784662248	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0116734382143932	0.0571768496395965	0.0413282647695778	0.0028924350901622	0.0003936097898921

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.0625
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C240/C240_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.5317388393320654	2.253009048203579	0.0242585784662248	0.5442656786920399	0.0970343138648992	37	P41208,Q02818,O43852,P0DP25,P80303,Q9BRK5,Q9NWM8,O95302,Q9Y680,Q6NUK1,O95202	11
+Beta tubulin, autoregulation binding site [IPR013838]	0.4555669050050963	0.4269199842881015	0.6694376091659717	0.9999999999999996	0.738689775631417	6	P04350,P07437,Q9BUF5,Q9BVA1,Q13885	5
+Peptidase M16, zinc-binding site [IPR001431]	0.4074200136146838	0.190599995297052	0.8488389938765737	1.0	0.905428260135012	5	O75439,P22695,Q10713,P14735	4

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CDK1", "CDK12", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "LYN", "MACF1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "FKBP14", "FKBP7", "FKBP9", "IDE", "LETM1", "NUCB1", "NUCB2", "PMPCA", "PMPCB", "SDF4", "SLC25A24", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:1a276e757e0027416564049b87cb6c22ae2d20221932a789a8697cce94111c33
+size 99324

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 271,
+    "title": "Average number of proteins per term",
+    "value": 2.623616236162362
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C240/C240_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9921795307718468	2.056646032229353	0.039720286903637	0.9999830257206648	0.1296891295287426	2	P30519	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8009692312575383	1.919255520626626	0.0549520041542055	0.99999977715775	0.1618694904977141	6	O60499,Q9P2W9,Q13190	3
+Tetraspanin, conserved site [IPR018503]	0.940156409384566	1.8406407160874303	0.0656742268994228	0.9999999898831076	0.174487406762192	2	O43657	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.6755808858107327	1.8035200173279748	0.0713065846253	0.9999999980347796	0.1814859750438356	10	Q9UBS8	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6936501858692368	1.6860355286005058	0.0917889564107987	0.9999999999953376	0.2182000630467233	8	P28072,P49721	2
+Sterol reductase, conserved site [IPR018083]	0.8085685141108527	1.286800769088097	0.1981637388193622	1.0	0.3533050869739945	2	Q14739	1
+Actin/actin-like conserved site [IPR020902]	0.7040816326530663	1.059635409415442	0.2893104979517034	1.0	0.4810008892325866	3	P61163,P61158	2
+Guanylate kinase, conserved site [IPR020590]	0.5957365601988177	1.0153566493733392	0.3099358496295274	1.0	0.5030350723341179	6	O14936,Q9NZW5,Q92796,Q00013	4
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.7432845970758295	1.0150475290023648	0.3100831717901497	1.0	0.5030350723341179	2	P04066	1
+Thioredoxin, conserved site [IPR017937]	0.4575669310343054	0.891985780594738	0.3724005540273714	1.0	0.5544996088124925	13	Q9H1E5,O43396,Q9H3N1,Q14554	4
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4829100347312546	0.8679193461894917	0.3854384872696732	1.0	0.5566963842054409	11	Q9Y394,Q06136	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.6725603536212272	0.7334906697401845	0.463259216435989	1.0	0.6277162382707651	2	Q9H3P7	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6180272108843484	0.7260517118774987	0.4678070698336891	1.0	0.6307249548503968	3	P26583,P09429	2
+DNA ligase, ATP-dependent, conserved site [IPR016059]	0.6314178850731099	0.5814042299681116	0.5609680472658627	1.0	0.7070806549258083	2	P49916	1
+Tubulin, conserved site [IPR017975]	0.4555669050050963	0.4269199842881015	0.6694376091659717	1.0	0.8063036974185328	6	P04350,P07437,Q9BUF5,Q9BVA1,Q13885	5
+ABC transporter-like, conserved site [IPR017871]	0.4188116020666106	0.4269162362612991	0.6694403391851287	1.0	0.8063036974185328	9	Q03518,O75027	2
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.523807537009024	0.401785775745327	0.6878416913623155	1.0	0.8175662208736294	3	Q16836	1
+14-3-3 protein, conserved site [IPR023409]	0.4187946884576051	0.2962263503646745	0.7670572267191984	1.0	0.8770991917337669	6	P27348,P31946,P63104,P62258,Q04917	5
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.5086705202312278	0.2224611316153297	0.8239549276507123	1.0	0.9265219310927096	2	P29692	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.4289115646258523	0.1628776064563722	0.8706148028197731	1.0	0.962622058871576	3	Q9Y2T2,Q9BXS5	2
+Inositol monophosphatase, conserved site [IPR020550]	0.4777286637198317	0.1623729758363383	0.8710121505771917	1.0	0.962622058871576	2	Q9NX62	1
+Clathrin adaptor complex, small chain [IPR000804]	0.4756885413124882	0.1588913164226196	0.8737545022725874	1.0	0.962622058871576	2	P53680	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.448146888813332	0.1176138127034708	0.9063736599585024	1.0	0.9632441641127614	2	P10644	1
+DnaJ domain, conserved site [IPR018253]	0.3262683760893635	0.0871615948618836	0.9305430659953596	1.0	0.9748437792239204	10	Q9NVH1,Q9Y2G8,Q96KC8	3
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.3301598095885709	0.039074243372978	0.9688311960928212	1.0	0.991004316732752	2	P25325	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.3261904761904832	0.0379472400635887	0.9697297480277732	1.0	0.991004316732752	3	O00429,P50570	2
+Ras GTPase-activating protein, conserved site [IPR023152]	0.2947976878612656	0.0341969430032062	0.972720104246908	1.0	0.991004316732752	2	Q13576	1
+Adenylate kinase, conserved site [IPR033690]	0.3654304185096941	0.0293179088426246	0.976611043850466	1.0	0.9912419209118962	4	P30085,P54819,P27144	3

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDX2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRM", "STAM", "STMN1", "STOM", "STX10", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB7", "ACBD3", "ACTR1A", "ACTR3", "AK2", "AK4", "AP1M1", "AP2S1", "AP3M1", "CASK", "CMPK1", "DHRS7", "DLG3", "DNAJC1", "DNAJC11", "DNAJC16", "DNM1L", "DNM2", "EEF1D", "FUCA1", "HADH", "HMGB1", "HMGB2", "HMOX2", "IMPAD1", "IQGAP2", "KDSR", "LBR", "LIG3", "MPP1", "MPP6", "MPST", "PDIA5", "PRKAR1A", "PSMB2", "PSMB6", "RNF14", "STX10", "STX18", "STX5", "TAP1", "TMX1", "TMX4", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TXNL1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Thioredoxin domain [IPR013766]", "2": "Dynamin, N-terminal [IPR045063]", "3": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "4": "Tubulin/FtsZ, GTPase domain [IPR003008]", "5": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "6": "Ubiquitin-associated domain [IPR015940]", "7": "14-3-3 domain [IPR023410]", "8": "Phosphoribosyltransferase domain [IPR000836]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:66779408051ed5f929b291a7b76daa5e0dda13cce00989b6c846131012b93c82
+size 425532

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Glutathione S-transferase, C-terminal-like [IPR010987]	4	12	2.457424549581949	0.0139937202337956	3.949029126213592	11.37621359223301	-0.0908035435769439	0.5323098181486043	2.6346872162188446	1.2313530457632356	0.9588413776865506	0.2992576122582335	0.0001327727267659	0.0027067874988798	1.391730242568295e-05	2.7582058036655703e-05	0.0007388687073799
+EF-hand domain [IPR002048]	13	43	2.431840988700669	0.0150223006888989	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.0292898971178211	0.086158736226278	0.0732279741082547	0.0104482115740687	0.0003176274883727
+Glutathione S-transferase, N-terminal [IPR004045]	4	8	2.3737382386990427	0.0176090290783146	2.4635922330097086	7.354368932038835	0.1379245375050955	0.5007649291980636	1.692684060559357	0.9479949918991396	0.9964823876403148	0.2990443112345751	2.575935005420449e-05	0.0012601973854463	2.6194869200470976e-06	3.221304592468962e-06	9.569573614901708e-05
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	6	2.263219216600329	0.023622179202831	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0009918498188417	0.0573151884822011	0.0057815105752346	0.0001405335592956	0.0001575214550341
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	4	12	2.2613778190665883	0.0237358710881254	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0012731085823663	0.0619434524836269	0.0002366501305723	0.0001991597833083	0.0002457979454447
+Phospholipid/glycerol acyltransferase [IPR002123]	3	5	2.0371804349654226	0.0416319637338105	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	1.0	1.0	1.0	1.0	0.0062633876942655
+Glutathione S-transferase, C-terminal [IPR004046]	3	10	2.0157530089200115	0.0438258095417531	4.296116504854369	9.6747572815534	-0.2960680455131327	0.4436917435255134	2.7947045045907837	0.7413211044633136	1.0797286822508236	0.3119102433166901	0.0012731085823663	0.0017760204843955	0.0002366501305723	0.0001991597833083	0.0027630263410089

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2943,
+    "annotations_size": 2490,
+    "title": "Average number of proteins per term",
+    "value": 2.1244979919678717
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C240/C240_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,172 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.7558500400713104	2.457424549581949	0.0139937202337956	0.9999999999999994	0.0626697183132214	12	P28161,P78417,Q9H7Z7,O15217	4
+EF-hand domain [IPR002048]	0.5341290685825979	2.431840988700669	0.0150223006888989	1.0	0.0653942809709064	43	P41208,Q02818,O43852,P0DP25,P80303,Q9BRK5,Q9NWM8,Q9UJS0,O95302,Q9Y680,Q6NUK1,Q8NF37,O95202	13
+Glutathione S-transferase, N-terminal [IPR004045]	0.844129396646471	2.3737382386990427	0.0176090290783146	1.0	0.0706062518599089	8	P28161,P78417,Q9H7Z7,O15217	4
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8828177240134435	2.263219216600329	0.023622179202831	1.0	0.084027466021499	6	O00264,Q8WUJ1,O43169,O15173	4
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.7180451429876387	2.2613778190665883	0.0237358710881254	1.0	0.0841913376202741	12	Q9NWM8,O95302,Q9Y680,P62942	4
+Phospholipid/glycerol acyltransferase [IPR002123]	0.8769929756298007	2.0371804349654226	0.0416319637338105	1.0	0.1229698572920381	5	Q9NUQ2,O15228,Q8NF37	3
+Glutathione S-transferase, C-terminal [IPR004046]	0.7178510673807291	2.0157530089200115	0.0438258095417531	1.0	0.1271549079817336	10	P28161,P78417,O15217	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9336734693877564	1.9748409197291728	0.048286203722764	1.0	0.1348237153103101	3	Q96G23,Q15629	2
+GOLD domain [IPR009038]	0.8097472700398083	1.9567292853778393	0.0503793048821124	1.0	0.1376997466042369	6	Q9H3P7,Q15363,Q9Y3B3,Q9BVK6	4
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8091700994411319	1.9542695057456376	0.050669353182096	1.0	0.1381891450420802	6	P09960,Q9NZ08	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8091700994411319	1.9542695057456376	0.050669353182096	1.0	0.1381891450420802	6	P09960,Q9NZ08	2
+FAD linked oxidase, N-terminal [IPR006094]	0.9666780006800416	1.951109450934145	0.0510440272029546	1.0	0.1386037379883937	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9666780006800416	1.951109450934145	0.0510440272029546	1.0	0.1386037379883937	2	Q15392	1
+MENTAL domain [IPR019498]	0.9625977558653532	1.934159061741881	0.0530935740556004	1.0	0.1427678179248867	2	O95772	1
+Reticulon [IPR003388]	0.912158106394468	1.890652617449485	0.0586707314128056	1.0	0.1503242485708923	3	O95197	1
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9452567154029268	1.8619363094794896	0.0626120682730615	1.0	0.1553710357300349	2	A6NIH7	1
+Glutaredoxin, PICOT-like [IPR033658]	0.9343760625637576	1.8164781242819024	0.0692970606511309	1.0	0.1670374453255721	2	O76003	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.812330417121702	1.7717746611110707	0.0764319703545088	1.0	0.1783398196402351	5	P16615,Q9HD20,Q9NQ11	3
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9190751445086752	1.7523867005486573	0.079707336736452	1.0	0.1834728655872837	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9190751445086752	1.7523867005486573	0.079707336736452	1.0	0.1834728655872837	2	Q9Y282	1
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7607876998965193	1.746038822050293	0.0808042061403604	1.0	0.1852693124212684	6	Q8N4Q0	1
+Glutaredoxin [IPR002109]	0.9148225760968852	1.733720313704633	0.082967720426915	1.0	0.1884941823567686	4	P35754,O76003	2
+IPT domain [IPR002909]	0.9020741244474682	1.6809769108943513	0.0927673994291082	1.0	0.2040554987442399	2	Q96KP1	1
+Zinc finger, RING-type [IPR001841]	0.5272739267368185	1.6398097592995098	0.1010447283823259	1.0	0.2135835090594155	20	Q9UBS8,O95628	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.6396919512448533	1.6198352259418451	0.1052676771026248	1.0	0.2184304299879465	10	O60499,Q13190,Q13277,Q5SQN1	4
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.8401360544217729	1.605206485246458	0.1084483707317436	1.0	0.2233552052291494	3	P61289,Q9UL46	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.8401360544217729	1.605206485246458	0.1084483707317436	1.0	0.2233552052291494	3	P61289,Q9UL46	2
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8772526351581127	1.5764344271293722	0.1149257195433495	1.0	0.230778259405597	2	Q8N2A8	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.8586131283872194	1.51589495351218	0.1295459165749766	1.0	0.2512222213953985	4	P21281	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.8586131283872194	1.51589495351218	0.1295459165749766	1.0	0.2512222213953985	4	P21281	1
+LEM domain [IPR003887]	0.7066703739058621	1.5088540193435027	0.1313360924487745	1.0	0.2543079148899175	6	P50402,P42166,Q86XL3	3
+Choline/carnitine acyltransferase domain [IPR039551]	0.8585515130907893	1.4975336035186717	0.1342544686363567	1.0	0.2583412881796972	2	P23786	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.5337195687333365	1.3839556962317747	0.1663720209339394	1.0	0.2970223706457053	14	Q9UHX1	1
+EB1, C-terminal [IPR004953]	0.8310098605916345	1.3813146983573636	0.1671822208080295	1.0	0.2977709083061471	2	Q15691	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.711684666901918	1.3482821829916427	0.1775676404330894	1.0	0.308552075576839	5	Q03518,O75027	2
+LEM-like domain [IPR013146]	0.821829309758592	1.3426170652578626	0.1793960016618132	1.0	0.3104211564544232	2	P42166	1
+ERAP1-like C-terminal domain [IPR024571]	0.7950148526896113	1.2676107555064406	0.2049369890925243	1.0	0.3363830605407947	4	Q9NZ08,Q9UIQ6	2
+Peptidase M28 [IPR007484]	0.7442737558032149	1.2203292621593764	0.2223400811853522	1.0	0.3558012867297731	3	Q969V3	1
+Band 7 domain [IPR001107]	0.5935598856472797	1.2050205517869226	0.2281953680998842	1.0	0.363535807145689	8	Q99623,O75955,P27105	3
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7397959183673561	1.2023598593872244	0.2292241341904788	1.0	0.3647080473701548	3	P16615,P05023	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7397959183673561	1.2023598593872244	0.2292241341904788	1.0	0.3647080473701548	3	P16615,P05023	2
+Thioredoxin domain [IPR013766]	0.4362230858801775	1.1828567452414522	0.2368659268081734	1.0	0.374711663120935	26	Q9BS26,Q9H1E5,Q9Y2G8,Q9H3N1,O76003	5
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.7144440146518661	1.1009083551701828	0.270936545305624	1.0	0.4103937773448315	3	P21912	1
+MD-2-related lipid-recognition domain [IPR003172]	0.7592655559333659	1.0808966245367433	0.2797431003072574	1.0	0.4188576787522977	2	P17900	1
+CTP synthase GATase domain [IPR033828]	0.7558653519211231	1.066838885808315	0.2860445957319726	1.0	0.4264589947961131	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.7558653519211231	1.066838885808315	0.2860445957319726	1.0	0.4264589947961131	2	Q9NRF8	1
+Syntaxin, N-terminal domain [IPR006011]	0.7013605442176792	1.0488216555161056	0.2942602086192987	1.0	0.4340686726670934	3	O15400,Q13277	2
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.7432845970758295	1.0150475290023648	0.3100831717901497	1.0	0.4531144939891273	2	P04066	1
+BAG domain [IPR003103]	0.6900675699517127	1.0040675776245724	0.315346041893235	1.0	0.4573160421165726	3	Q9UL15	1
+Legume-like lectin [IPR005052]	0.7358041482488986	0.9844375927676065	0.3249004019280814	1.0	0.4687149483203492	2	P49257	1
+Tim44-like domain [IPR007379]	0.7320639238354343	0.9691899963680038	0.3324504013459797	1.0	0.4757479881330398	2	O43615	1
+SCP2 sterol-binding domain [IPR003033]	0.6802721088435391	0.9654343202568624	0.334327318330704	1.0	0.4773365955524387	3	P22307,P51659	2
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.5578665604890398	0.9354586067380264	0.3495520059009658	1.0	0.4914649885338254	7	Q8N4Q0	1
+Zinc finger, CHHC-type [IPR012996]	0.6710884353741454	0.9293975500187174	0.3526830970315042	1.0	0.4932857145739831	3	P55795,P52597	2
+PITH domain [IPR010400]	0.7215232913974912	0.9264449328007616	0.3542148022724023	1.0	0.4932857145739831	2	O43396	1
+CRIB domain [IPR000095]	0.7164229853791232	0.905891005721707	0.3649935454148534	1.0	0.5035091014310166	2	Q13177	1
+p21 activated kinase binding domain [IPR033923]	0.7164229853791232	0.905891005721707	0.3649935454148534	1.0	0.5035091014310166	2	Q13177	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.7150629037742264	0.9004251545872031	0.3678940392526058	1.0	0.5070809666509368	2	Q9H993	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.6605442176870658	0.8882743212812045	0.3743932090258584	1.0	0.5133475167810503	3	Q06203,P08243	2
+L27 domain [IPR004172]	0.6026939747176272	0.8872494635643485	0.3749446071620124	1.0	0.5136510181744505	5	O14936,Q9NZW5	2
+SUN coiled coil domain 2 [IPR040994]	0.7058823529411771	0.8637082464061155	0.3877481824106403	1.0	0.5209331062152217	2	O94901	1
+CBS domain [IPR000644]	0.5911916425025482	0.8395619882313325	0.4011540194749687	1.0	0.5335862759042053	5	P51790,P51798	2
+Glutamine amidotransferase [IPR017926]	0.6764081651863276	0.8114032043497713	0.4171341595792344	1.0	0.5478143195008683	4	Q9NRF8,P49915	2
+EF hand associated, type-2 [IPR013567]	0.6786807208432525	0.7570030011219454	0.4490480644674943	1.0	0.5707788993553643	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.6786807208432525	0.7570030011219454	0.4490480644674943	1.0	0.5707788993553643	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.6786807208432525	0.7570030011219454	0.4490480644674943	1.0	0.5707788993553643	2	Q8IXI2	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.6725603536212272	0.7334906697401845	0.463259216435989	1.0	0.5828779428628664	2	Q9H3P7	1
+EH domain-containing protein, N-terminal [IPR031692]	0.6671200272016344	0.7127638390654663	0.475991905431874	1.0	0.5905430216867794	2	Q9H223	1
+Domain of unknown function DUF5600 [IPR040990]	0.6671200272016344	0.7127638390654663	0.475991905431874	1.0	0.5905430216867794	2	Q9H223	1
+VHS domain [IPR002014]	0.5975093271369857	0.6504936766546857	0.5153733849549833	1.0	0.6247861843510232	3	O14964	1
+L27 domain, C-terminal [IPR014775]	0.6305625266002037	0.6443508835739139	0.5193479267413952	1.0	0.6266290383752255	4	O14936	1
+Dynamin, N-terminal [IPR045063]	0.4848796125171544	0.6070496353830817	0.5438179726244634	1.0	0.6448127389690066	7	Q8IWA4,Q9H4M9,Q9H223,O00429,O60313	5
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.4848796125171544	0.6070496353830817	0.5438179726244634	1.0	0.6448127389690066	7	Q8IWA4,Q9H4M9,Q9H223,O00429,O60313	5
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.5792454086598757	0.5851882950259824	0.5584211144122389	1.0	0.6577429398706125	3	Q99797	1
+DNA ligase, ATP-dependent, central [IPR012310]	0.6314178850731099	0.5814042299681116	0.5609680472658627	1.0	0.6598065364629183	2	P49916	1
+DNA ligase, ATP-dependent, N-terminal [IPR012308]	0.6314178850731099	0.5814042299681116	0.5609680472658627	1.0	0.6598065364629183	2	P49916	1
+DNA ligase, ATP-dependent, C-terminal [IPR012309]	0.6314178850731099	0.5814042299681116	0.5609680472658627	1.0	0.6598065364629183	2	P49916	1
+Tudor domain [IPR002999]	0.4579630596139267	0.5596223556961674	0.5757370529301546	1.0	0.6702933141877775	8	Q92667,Q9Y2W6,Q16637,Q14739	4
+Arginyl-tRNA synthetase, catalytic core domain [IPR035684]	0.6188371302278192	0.5373508009783808	0.591025320750791	1.0	0.6851271176301068	2	P54136	1
+DALR anticodon binding [IPR008909]	0.6188371302278192	0.5373508009783808	0.591025320750791	1.0	0.6851271176301068	2	P54136	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.6137368242094581	0.5198705899688082	0.6031537749824594	1.0	0.6965922540381836	2	P18031	1
+Ribosomal protein S10 domain [IPR027486]	0.6082964977898747	0.5014796881805299	0.616033569350843	1.0	0.7085097402695607	2	P82664	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4364011090813989	0.4645947921011928	0.6422216624730706	1.0	0.7315333666779258	8	P11310,Q15067	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.4555669050050963	0.4269199842881015	0.6694376091659717	1.0	0.7530774162795801	6	P04350,P07437,Q9BUF5,Q9BVA1,Q13885	5
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.4555669050050963	0.4269199842881015	0.6694376091659717	1.0	0.7530774162795801	6	P04350,P07437,Q9BUF5,Q9BVA1,Q13885	5
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4188116020666106	0.4269162362612991	0.6694403391851287	1.0	0.7530774162795801	9	Q03518,O75027	2
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.523807537009024	0.401785775745327	0.6878416913623155	1.0	0.7704569552371415	3	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.523807537009024	0.401785775745327	0.6878416913623155	1.0	0.7704569552371415	3	Q16836	1
+Ubiquitin-associated domain [IPR015940]	0.3720754336699942	0.3941036630864188	0.6935045066719219	1.0	0.7750566524295716	13	Q04323,Q9UHD9,Q13501,Q14157,Q9NZ09	5
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5510167018130234	0.3826527669335611	0.7019772401612765	1.0	0.7831197706100261	4	O00303	1
+B-box, C-terminal [IPR003649]	0.5142506425122446	0.3729352198492728	0.7091966582508664	1.0	0.7897583537766804	3	O15164	1
+Longin domain [IPR010908]	0.5115646258503371	0.364995560553895	0.7151147201488142	1.0	0.7956370210770989	3	P51809,O75396	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.5115646258503371	0.364995560553895	0.7151147201488142	1.0	0.7956370210770989	3	P51809,O75396	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5627337640258517	0.359104021236746	0.7195172734696942	1.0	0.7998205405980083	2	Q92945	1
+Peptidase M16, N-terminal [IPR011765]	0.4134509475092491	0.3187511290834863	0.7499152399066105	1.0	0.8269658757163242	7	P22695,Q10713	2
+Peptidase M16, C-terminal [IPR007863]	0.4134509475092491	0.3187511290834863	0.7499152399066105	1.0	0.8269658757163242	7	P22695,Q10713	2
+Cyclin, C-terminal domain [IPR004367]	0.5416524991499535	0.3012634092171083	0.7632136407243304	1.0	0.8365686091032036	2	P14635	1
+Cyclin, N-terminal [IPR006671]	0.5416524991499535	0.3012634092171083	0.7632136407243304	1.0	0.8365686091032036	2	P14635	1
+Cyclin-like [IPR013763]	0.5416524991499535	0.3012634092171083	0.7632136407243304	1.0	0.8365686091032036	2	P14635	1
+BAR domain [IPR004148]	0.488775510204077	0.3008143969203576	0.763556029445589	1.0	0.8365686091032036	3	Q9Y371,Q99961	2
+14-3-3 domain [IPR023410]	0.4187946884576051	0.2962263503646745	0.7670572267191984	1.0	0.8395483492443094	6	P27348,P31946,P63104,P62258,Q04917	5
+MIT domain [IPR007330]	0.4799319727891147	0.2775309849589308	0.7813724172977916	1.0	0.8533409294173251	3	Q8N0X7,Q9UN37	2
+Chromo shadow domain [IPR008251]	0.4768707482993185	0.269693859757924	0.787395784774855	1.0	0.8579037653904165	3	Q13185,P45973	2
+Chromo domain subgroup [IPR017984]	0.4768707482993185	0.269693859757924	0.787395784774855	1.0	0.8579037653904165	3	Q13185,P45973	2
+Extended synaptotagmin, C2A domain [IPR037733]	0.5273716422985443	0.2653281526901409	0.7907566787504066	1.0	0.8590681195848657	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5273716422985443	0.2653281526901409	0.7907566787504066	1.0	0.8590681195848657	2	Q9BSJ8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5273716422985443	0.2653281526901409	0.7907566787504066	1.0	0.8590681195848657	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5273716422985443	0.2653281526901409	0.7907566787504066	1.0	0.8590681195848657	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5273716422985443	0.2653281526901409	0.7907566787504066	1.0	0.8590681195848657	2	Q9BSJ8	1
+Phosphoribosyltransferase domain [IPR000836]	0.4051753489955694	0.2521235384382089	0.8009455764848432	1.0	0.8674878144616179	6	P07741,P11908,P00492,O60256,Q06203	5
+AP complex, mu/sigma subunit [IPR022775]	0.4292035398230132	0.2494811218621987	0.8029886419081593	1.0	0.8689446842030929	5	P53680,P48444,Q9Y2T2,P61923	4
+Domain of unknown function DUF1899 [IPR015048]	0.5158109486569296	0.2382560820597705	0.811682482017845	1.0	0.8749304676296251	2	Q9ULV4	1
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.4588435374149616	0.225951783369296	0.8212389217964713	1.0	0.8821764086597125	3	P00390,P09622	2
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.5086705202312278	0.2224611316153297	0.8239549276507123	1.0	0.8839499223827116	2	P29692	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.5086705202312278	0.2224611316153297	0.8239549276507123	1.0	0.8839499223827116	2	P29692	1
+Rab-GTPase-TBC domain [IPR000195]	0.3893818838457766	0.2043504387896325	0.8380796570091871	1.0	0.895954116470713	6	Q9NVG8,Q9Y3P9,Q8TC07	3
+STAT transcription factor, protein interaction [IPR013799]	0.4909894593675735	0.1864520508598406	0.8520902773082784	1.0	0.9082640370280878	2	P42224	1
+STAT transcription factor, DNA-binding [IPR013801]	0.4909894593675735	0.1864520508598406	0.8520902773082784	1.0	0.9082640370280878	2	P42224	1
+STAT transcription factor, all-alpha domain [IPR013800]	0.4909894593675735	0.1864520508598406	0.8520902773082784	1.0	0.9082640370280878	2	P42224	1
+Thioredoxin-like fold [IPR012336]	0.4896293777626784	0.1838667014709834	0.8541180277869682	1.0	0.9092577551045536	2	Q6DKJ4	1
+EH domain [IPR000261]	0.4722457999832884	0.1807031243494976	0.8566006062857716	1.0	0.9107324977162986	4	Q9H223,Q96D71	2
+Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]	0.4340136054421649	0.1727598451936505	0.8628402012678196	1.0	0.9161927936703071	3	Q14558,O60256	2
+Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]	0.4797687861271695	0.1659139422342279	0.868224675251247	1.0	0.9207323004155048	2	Q9UN37	1
+TIP49, P-loop domain [IPR010339]	0.4685481128867722	0.1471709487666986	0.8829970904076079	1.0	0.9328225520216138	2	Q9Y230	1
+RuvB-like, AAA-lid domain [IPR041048]	0.4685481128867722	0.1471709487666986	0.8829970904076079	1.0	0.9328225520216138	2	Q9Y230	1
+Heat shock chaperonin-binding [IPR006636]	0.4520012611131292	0.1408212774213279	0.8880111336142378	1.0	0.9377216805341188	4	P54727,Q9UHD9	2
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.4139455782312915	0.1359833003617342	0.8918344827073503	1.0	0.9387103809329284	3	O00203,Q10567	2
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.448146888813332	0.1176138127034708	0.9063736599585024	1.0	0.9506615051797266	2	P10644	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3403521358124579	0.1111359977199649	0.9115085034900154	1.0	0.9535194458925592	8	Q92905,O00303	2
+FAD dependent oxidoreductase [IPR006076]	0.4300782579108495	0.1036570747269757	0.9174414924848762	1.0	0.9571324362814484	4	Q9H9P8,P43304,Q96CU9	3
+CELF1/2, RNA recognition motif 1 [IPR034196]	0.43556613396804	0.1021976492464846	0.9185997936170374	1.0	0.9571324362814484	2	Q92879	1
+CELF1/2, RNA recognition motif 2 [IPR034198]	0.43556613396804	0.1021976492464846	0.9185997936170374	1.0	0.9571324362814484	2	Q92879	1
+CELF1/2, RNA recognition motif 3 [IPR034199]	0.43556613396804	0.1021976492464846	0.9185997936170374	1.0	0.9571324362814484	2	Q92879	1
+Mu homology domain [IPR028565]	0.4290575025518884	0.1020797393965677	0.9186933826155268	1.0	0.9571324362814484	4	P48444,Q9BXS5,Q9Y2T2	3
+Replication factor C, C-terminal [IPR013748]	0.3914965986394568	0.1014839648524251	0.9191662860318714	1.0	0.9572246140607946	3	P35249,P40937	2
+Pre-PUA domain [IPR041366]	0.432845970758246	0.099135468252568	0.9210307111891628	1.0	0.957964273542613	2	Q9ULC4	1
+Methylglyoxal synthase-like domain [IPR011607]	0.4318259095545799	0.0980114455046318	0.9219232049300788	1.0	0.958492183831272	2	P31939	1
+GRAM domain [IPR004182]	0.386054421768705	0.094159901588383	0.9249821371023526	1.0	0.9604693583756704	3	Q969T9,Q66K14	2
+Nucleotidyl transferase domain [IPR005835]	0.3853741496598653	0.0932723781998921	0.9256871754051996	1.0	0.9608007781404532	3	Q9NR50,Q9Y5P6	2
+BSD domain [IPR005607]	0.4229853791227454	0.0888142736931096	0.9292295137544822	1.0	0.962566679505841	2	Q96A49	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.4223053383202992	0.0881465273922169	0.929760216758658	1.0	0.9626167656180002	2	P13674	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.3782312925170082	0.084324300084584	0.9327985925315154	1.0	0.9641629287685652	3	P01889,P10321	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.3782312925170082	0.084324300084584	0.9327985925315154	1.0	0.9641629287685652	3	P01889,P10321	2
+MoaB/Mog domain [IPR001453]	0.4121047262835746	0.0787873652634207	0.9372017538648793	1.0	0.96743706549461	2	Q9NQX3	1
+Peptidase M16, middle/third domain [IPR032632]	0.4070044202652183	0.0745551091561149	0.9405686923688604	1.0	0.9701806313166786	2	P14735	1
+Dynamin, GTPase domain [IPR001401]	0.3979105996832103	0.0603650108724452	0.95186492509622	1.0	0.9770365077465382	4	O00429	1
+Myotubularin-like phosphatase domain [IPR010569]	0.3859231553893232	0.0599704817173441	0.9521791445387986	1.0	0.9770365077465382	2	Q9Y217	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.3974140864239498	0.0597982656117089	0.9523163069481316	1.0	0.9770365077465382	4	Q16181,Q15019,Q9NVA2	3
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.3513605442176908	0.0564800126047249	0.9549594177356888	1.0	0.9793447076449197	3	Q9H0H5,Q92974	2
+Ras GTPase-activating domain [IPR001936]	0.3449107512052637	0.0510817342478705	0.9592603909474168	1.0	0.9820923674658956	3	Q13576	1
+Guanylate kinase-like domain [IPR008144]	0.3211978523902887	0.0498105158773011	0.9602733866286588	1.0	0.9820923674658956	7	O14936,Q9NZW5,Q92796,Q00013	4
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.3211978523902887	0.0498105158773011	0.9602733866286588	1.0	0.9820923674658956	7	O14936,Q9NZW5,Q92796,Q00013	4
+Major facilitator superfamily domain [IPR020846]	0.3364332982195605	0.0496521801051417	0.960399564168456	1.0	0.9820923674658956	5	Q7L0J3	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.386185777475333	0.0477691019051615	0.961900261540792	1.0	0.9828197173724136	4	Q06124,Q9Y217,P18031	3
+Major sperm protein (MSP) domain [IPR000535]	0.3370748299319763	0.0451408765295858	0.9639950198547348	1.0	0.984152514884518	3	Q8NHP6,Q9P0L0	2
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.3515810948656895	0.0446448210897764	0.9643904161920578	1.0	0.984152514884518	2	Q9NSV4	1
+Formyl transferase, N-terminal [IPR002376]	0.3349200952057081	0.0401030066991988	0.9680110047323862	1.0	0.9863672682145244	2	Q96DP5	1
+Peptidase M20, dimerisation domain [IPR011650]	0.3318599115946989	0.0394292703775257	0.9685481436622176	1.0	0.9863672682145244	2	Q8IYS1	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.3159933965999017	0.0393195199784948	0.968635643957072	1.0	0.9863672682145244	7	P11310	1
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.3159933965999017	0.0393195199784948	0.968635643957072	1.0	0.9863672682145244	7	P11310	1
+Dynamin GTPase effector [IPR003130]	0.3261904761904832	0.0379472400635887	0.9697297480277732	1.0	0.9863672682145244	3	O00429,P50570	2
+GTPase effector domain [IPR020850]	0.3261904761904832	0.0379472400635887	0.9697297480277732	1.0	0.9863672682145244	3	O00429,P50570	2
+Dynamin stalk domain [IPR000375]	0.3261904761904832	0.0379472400635887	0.9697297480277732	1.0	0.9863672682145244	3	O00429,P50570	2
+JmjC domain [IPR003347]	0.3732028569923968	0.0356752260908042	0.9715413246895416	1.0	0.9878064101580069	4	Q8IUF8	1
+RasGAP protein, C-terminal [IPR000593]	0.2947976878612656	0.0341969430032062	0.972720104246908	1.0	0.988501589924399	2	Q13576	1
+UAS [IPR006577]	0.2900374022441279	0.03382207225174	0.9730190349014868	1.0	0.988501589924399	2	Q96CS3	1
+Cold shock domain [IPR011129]	0.3683383762560291	0.0316216013127962	0.9747738166460804	1.0	0.9890736770369764	4	Q9Y2V2	1
+Cold-shock protein, DNA-binding [IPR002059]	0.3683383762560291	0.0316216013127962	0.9747738166460804	1.0	0.9890736770369764	4	Q9Y2V2	1
+Cold-shock (CSD) domain [IPR019844]	0.3683383762560291	0.0316216013127962	0.9747738166460804	1.0	0.9890736770369764	4	Q9Y2V2	1
+Beta-Casp domain [IPR022712]	0.3010204081632719	0.025475611292054	0.9796756015421992	1.0	0.9920261276291484	3	Q9UKF6,Q5TA45	2
+Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]	0.3010204081632719	0.025475611292054	0.9796756015421992	1.0	0.9920261276291484	3	Q9UKF6,Q5TA45	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Small GTPase superfamily, ARF/SAR type [IPR006689]", "1": "Mitochondrial carrier protein [IPR002067]"}