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6addfa1 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Regulation of runx3 expression and activity 0.7119059983090579 2.863559587019679 0.0041891001389224 0.9969128499374772 0.4777722896967492 35 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Degradation of axin 0.7119059983090579 2.863559587019679 0.0041891001389224 0.9969128499374772 0.4777722896967492 35 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Cross presentation of soluble exogenous antigens endosomes 0.7125690408035228 2.846961538952449 0.0044138694715689 0.9977376504653802 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,Q9UBG0,P25788,O43242,P28066,P25787,O00487 25
Cyclin a cdk2 associated events at s phase entry 0.7156888659920162 2.8047569425858683 0.0050354535468264 0.9990426445586942 0.4777722896967492 39 Q15008,P25789,P11802,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,Q13616,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 28
Scf skp2 mediated degradation of p27 p21 0.7156888659920162 2.8047569425858683 0.0050354535468264 0.9990426445586942 0.4777722896967492 39 Q15008,P25789,P11802,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,Q13616,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 28
Regulation of ras by gaps 0.7044421710336637 2.7965106346367192 0.0051657710867101 0.999200643124692 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 24
Degradation of dvl 0.7044421710336637 2.7965106346367192 0.0051657710867101 0.999200643124692 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 24
Regulation of runx2 expression and activity 0.7153127316752779 2.7821086048729526 0.0054006963882662 0.9994225642419696 0.4777722896967492 40 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,Q13616,Q9UNE7,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 28
Asymmetric localization of pcp proteins 0.7014363673034749 2.777779219350378 0.0054731792920301 0.9994776997497564 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Degradation of gli1 by the proteasome 0.7102277837806888 2.7708743313031614 0.0055905998820324 0.9995560752591568 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 27
Regulation of pten stability and activity 0.7052251977542147 2.760186255536464 0.0057768415971326 0.999656998694507 0.4777722896967492 38 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q9UNE7,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 25
G1 s dna damage checkpoints 0.6984363395785695 2.7590450638942947 0.0057970540320959 0.9996664676949252 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Stabilization of p53 0.6984363395785695 2.7590450638942947 0.0057970540320959 0.9996664676949252 0.4777722896967492 36 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Tnfr2 non canonical nf kb pathway 0.7079151165154515 2.7564877715203724 0.0058425797297994 0.999686849511742 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,Q8TBC4,O00487 27
Dectin 1 mediated noncanonical nf kb signaling 0.7079151165154517 2.7564877715203724 0.0058425797297994 0.999686849511742 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,Q8TBC4,O00487 27
Negative regulation of notch4 signaling 0.7062453644506195 2.7460865825791947 0.0060310844590154 0.999758815398344 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 26
Auf1 hnrnp d0 binds and destabilizes mrna 0.7018988206875978 2.7189557886780316 0.0065488360729986 0.9998823039022944 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q14103,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 25
Cellular response to hypoxia 0.6917758578326695 2.6966014297828007 0.0070051060072116 0.9999374769533056 0.4777722896967492 37 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 24
Hedgehog on state 0.6979587336877893 2.6942927496827895 0.0070538179283303 0.999941560965113 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 25
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.7135274041317939 2.67073955325769 0.0075684345622593 0.9999713790796236 0.4777722896967492 45 Q15008,P25789,Q13200,Q96DE5,O00231,P28072,P28074,P48556,P55036,P25786,Q9UJX3,P20618,Q13309,P28070,P49721,Q9UJX4,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9UJX6,P25788,O43242,P28066,P25787,Q16763,Q9UJX2,P53350,O00487 32
Cdt1 association with the cdc6 orc origin complex 0.6886309648827997 2.635641632437559 0.0083978371000945 0.9999909491401796 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q9UJA3,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 25
Hedgehog ligand biogenesis 0.6872992312109245 2.627237610691423 0.0086081201522256 0.999993241393284 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,Q9UBV2,O00487 25
Uch proteinases 0.6957730429888623 2.619615628511283 0.008802892419401 0.9999948434898897 0.4777722896967492 42 P28070,P49721,P51665,P60900,Q99436,O00231,P28072,Q8NB78,Q9Y5K5,P28074,P48556,P55036,P49720,P25786,P25788,O00487,P20618,O15294 18
Metabolism of polyamines 0.6823955034059501 2.6167951561592453 0.0088759589570359 0.9999953412363406 0.4777722896967492 38 Q15008,P25789,Q13200,P61289,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 25
Runx1 regulates transcription of genes involved in differentiation of hscs 0.6847695345708256 2.6112528011167253 0.0090211180334898 0.9999961921632926 0.4777722896967492 39 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,O00487 25
Downstream signaling events of b cell receptor bcr 0.6752873054380794 2.551091194881145 0.0107386222831797 0.9999996506013684 0.5033793766349226 39 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 26
Interleukin 1 signaling 0.6790702754624824 2.5342533302254733 0.0112687232896118 0.999999832975102 0.5033793766349226 41 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 26
Clec7a dectin 1 signaling 0.6810546244504398 2.5265648185482186 0.0115184131069683 0.9999998820385952 0.5033793766349226 42 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,O43865,P25788,O43242,P28066,P25787,Q8TBC4,O00487 28
Orc1 removal from chromatin 0.6967272403682165 2.5061397608098943 0.0122057363200469 0.9999999547341978 0.5033793766349226 48 Q15008,P25789,P25205,Q13200,P33993,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,Q14566,P49721,Q13616,Q9UJA3,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,P49736,O43242,P28066,P33991,P25787,O00487 33
Transcriptional regulation by runx3 0.6685277935489976 2.4874338616615685 0.0128668375526381 0.999999981994842 0.5033793766349226 40 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 24
Signaling by notch4 0.6714344151646293 2.4652505654925383 0.0136917467821089 0.9999999943056682 0.5033793766349226 42 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 26
Fceri mediated nf kb activation 0.6632784716188832 2.4537878480478708 0.0141360352316035 0.999999996938045 0.5033793766349226 40 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 26
Interleukin 1 family signaling 0.6694118709310841 2.4320605940099456 0.0150131954657815 0.9999999991011692 0.5033793766349226 43 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q06124,P25788,O43242,P28066,P25787,O00487 27
Transcriptional regulation by runx2 0.6818387075268283 2.4117038561104835 0.0158781726546375 0.9999999997319066 0.5033793766349226 48 Q15008,P25789,P11802,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P17931,P20618,Q13309,P28070,P49721,Q13616,Q9UNE7,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,P07947,O43242,P28066,P25787,O00487 31
Signaling by the b cell receptor bcr 0.6629556275581828 2.410886150141641 0.0159138151924214 0.9999999997449492 0.5033793766349226 42 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,O43865,P25788,O43242,P28066,P25787,P62993,O00487 28
Apc c mediated degradation of cell cycle proteins 0.6939346768138069 2.4105589603983804 0.0159280965826456 0.9999999997499952 0.5033793766349226 52 Q15008,P25789,Q13200,Q96DE5,O00231,P28072,Q13257,P63208,P28074,P48556,P55036,P25786,Q9UJX3,P20618,Q13309,P28070,P49721,Q13616,Q9UJX4,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9UJX6,P25788,O43242,P28066,P25787,Q16763,Q9UJX2,P53350,O00487 35
Pcp ce pathway 0.6683187139788933 2.3648484302554964 0.0180374512824017 0.999999999986977 0.5033793766349226 46 Q15008,P25789,P53680,Q13200,P61289,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,O94973,P28066,P25787,O00487 27
Hedgehog off state 0.6739606049999078 2.361369355263881 0.0182075860494375 0.9999999999897414 0.5033793766349226 48 Q15008,P25789,Q13200,P61289,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,Q13616,Q9BVA1,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 29
Switching of origins to a post replicative state 0.6976225119491061 2.3573976590843064 0.0184035273081011 0.9999999999922066 0.5033793766349226 56 Q15008,P25789,P25205,Q13200,Q96DE5,P33993,O00231,P28072,P63208,P28074,P48556,P55036,P25786,Q9UJX3,P20618,Q13309,P28070,Q14566,P49721,Q13616,Q9UJX4,Q9UJA3,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9UJX6,P25788,P49736,O43242,P28066,P33991,P25787,Q16763,Q9UJX2,O00487 39
Regulation of hmox1 expression and activity 0.6593230019019566 2.347022410467636 0.0189241165160281 0.999999999996246 0.5033793766349226 44 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,Q13616,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 27
The role of gtse1 in g2 m progression after g2 checkpoint 0.6664028192084614 2.3326458226166373 0.0196667418495397 0.9999999999986768 0.5033793766349226 47 Q15008,P25789,Q13200,P61289,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q9BVA1,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,Q15691,P53350,O00487 28
Degradation of beta catenin by the destruction complex 0.6612995574442064 2.319673725375961 0.0203585342360619 0.9999999999994994 0.5033793766349226 46 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,P30153,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q13363,P25788,O43242,P28066,Q16537,P25787,O00487 29
Mapk6 mapk4 signaling 0.6585150967279686 2.2817800853273216 0.0225023271042303 0.9999999999999756 0.5033793766349226 47 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13153,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9HCE1,O14980,P25788,O43242,P28066,P25787,O00487 27
Tcr signaling 0.6485315159592647 2.2771527736532367 0.0227771041801116 0.9999999999999832 0.5033793766349226 44 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,Q13153,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,O00487 27
Beta catenin independent wnt signaling 0.6642582699692413 2.2596891025531267 0.0238405531141459 0.9999999999999964 0.5033793766349226 50 Q15008,P25789,P53680,Q13200,P61289,O00231,P28072,P28074,P48556,P55036,P25786,Q9UBI6,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9HCE1,P25788,O43242,O94973,P09471,P28066,P25787,O00487 30
Metabolism of folate and pterines 0.8427972488258608 2.258483357934996 0.023915540971128 0.9999999999999968 0.5033793766349226 8 P34896,Q9H2D1,P41440 3
C type lectin receptors clrs 0.6528395728462606 2.245023676474454 0.0247666126535743 0.999999999999999 0.5033793766349226 47 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,Q13153,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,O43865,P25788,O43242,P28066,P25787,Q8TBC4,O00487 29
Cargo trafficking to the periciliary membrane 0.6956638335558413 2.209009463233854 0.0271739826927122 1.0 0.5125832077789686 20 O43924,A6NIH7 2
Ras processing 0.9020746536577696 2.188964566478917 0.0285994155224895 1.0 0.5262100402063056 5 O43924 1
Defective cftr causes cystic fibrosis 0.6110844930965549 2.0922113803248448 0.0364196109231251 1.0 0.5855083610557255 41 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,Q9UBV2,O00487 25
Abc transporter disorders 0.6110844930965549 2.0922113803248448 0.0364196109231251 1.0 0.5855083610557255 41 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,P25788,O43242,P28066,P25787,Q9UBV2,O00487 25
Cyclin a b1 b2 associated events during g2 m transition 0.7944566880571257 2.0905580761474525 0.0365676972046422 1.0 0.5855083610557255 9 P30307,P30153,Q9Y570,P53350,O14980 5
Signaling by hedgehog 0.6443286272516418 2.0525644329232446 0.0401148400028472 1.0 0.6277060759536441 54 Q15008,P25789,Q13200,P61289,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,Q13616,Q9BVA1,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,P25788,O43242,P28066,P25787,Q9UBV2,O00487 30
Aurka activation by tpx2 0.5695838682131517 2.0242664431439654 0.0429427443787626 1.0 0.6358296667694213 31 O75935,O43805,P53350,O95684,Q9H6D7 5
Recruitment of mitotic centrosome proteins and complexes 0.5687416354354847 2.0185304221449454 0.0435360490873475 1.0 0.6377568041838039 31 O75935,O43805,P53350,O95684,Q9H6D7 5
Dna replication pre initiation 0.6521241902563266 2.0082563424529605 0.0446160585588204 1.0 0.6466980277420606 59 Q15008,P25789,Q14181,P09884,P25205,Q13200,P33993,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,Q14566,P49721,P56282,Q9UJA3,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9NR33,P25788,P49736,O43242,P28066,P33991,P25787,O00487 34
Hur elavl1 binds and stabilizes mrna 0.9123830911586972 1.998955487785735 0.045613170214773 1.0 0.6542639102681511 4 Q01105 1
Fc epsilon receptor fceri signaling 0.6172525967885257 1.9718923996823687 0.0486218911172435 1.0 0.6707616666228715 49 Q15008,P25789,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q13616,Q13153,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,O43865,P25788,O43242,P28066,P25787,P62993,O00487 29
Anchoring of the basal body to the plasma membrane 0.5605932470180154 1.9628751637822153 0.0496606812959283 1.0 0.6707616666228715 31 O75935,O43805,P53350,O95684,Q9H6D7 5
Resolution of d loop structures 0.7791832058175527 1.962656942748029 0.0496860493794719 1.0 0.6707616666228715 7 Q9UQ84 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.7791832058175527 1.962656942748029 0.0496860493794719 1.0 0.6707616666228715 7 Q9UQ84 1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.7696715769171023 1.9518102690380377 0.0509607346383513 1.0 0.679844736501315 8 P30307,O95628 2
Unwinding of dna 0.7509443942529771 1.9025745139679895 0.0570960873231531 1.0 0.7158311213183347 9 Q14566,P33991,P25205,Q9UJA3,Q9BRT9,P49736 6
Regulation of mrna stability by proteins that bind au rich elements 0.6327818194819934 1.900478552805578 0.0573703469122814 1.0 0.7158311213183347 58 Q15008,P25789,Q13200,O00231,P28072,Q92945,P28074,P48556,P55036,P25786,P20618,Q01105,P28070,P49721,Q14103,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9Y3B2,O14980,P25788,O43242,P28066,P25787,Q15024,Q92973,O00487 31
Diseases of mitotic cell cycle 0.7034768178375833 1.7960659362645677 0.072484031145759 1.0 0.7303110606981126 12 P11802,Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q00534,Q9UJX3,Q13309 8
Antigen processing cross presentation 0.5906722147238013 1.7943698707864668 0.0727541525967077 1.0 0.7303110606981126 49 Q15008,P25789,Q13200,O00231,P28072,Q9UIQ6,P28074,P48556,P55036,P25786,P20618,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q9UBG0,P25788,O43242,P28066,P25787,O00487 26
Cytoprotection by hmox1 0.6231425887486689 1.7805852156294772 0.0749802367813099 1.0 0.7303110606981126 61 O00231,P28072,Q96ST3,P63208,P28074,P48556,P55036,P25786,Q86X55,P20618,Q13309,P28070,P49721,Q13616,P49720,Q9Y6N1,P51665,P60900,Q99436,P30519,P25788,O00487 22
Dna strand elongation 0.5241460356754866 1.7760346121133552 0.0757272124273897 1.0 0.7303110606981126 28 Q14181,P09884,Q14566,P33991,P25205,P41440,Q9UJA3,Q9BRT9,P40938,P28340,P35249,P49736 12
Hdms demethylate histones 0.7316018919451283 1.7615248026997767 0.0781496188239714 1.0 0.7303110606981126 7 Q8NB78,P29375 2
Activation of atr in response to replication stress 0.6376973706935511 1.7606787736411598 0.0782927873819376 1.0 0.7303110606981126 18 P30307,Q14566,P33991,P25205,Q9UJA3,P40938,P35249,P49736 8
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.7162550317610111 1.750170880637548 0.0800888318896442 1.0 0.7303110606981126 9 Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q9UJX3,Q13309 6
Interleukin 12 family signaling 0.5170033154526363 1.7479804282130549 0.0804674165134271 1.0 0.7303110606981126 27 P14174,P78417,Q13126,P52597 4
Rab gefs exchange gtp for gdp on rabs 0.5595998413620381 1.7414747576944758 0.0816003941564538 1.0 0.7303110606981126 24 P50395 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.7252750373190029 1.7344941869775183 0.0828304362790854 1.0 0.7303110606981126 7 O60725 1
Downregulation of tgf beta receptor signaling 0.7179848484607543 1.680280709280954 0.0929027125326258 1.0 0.7322462621110208 6 O14980,Q9UNE7 2
Methylation 0.7172576288965571 1.6772070030969597 0.093502010091564 1.0 0.7322462621110208 6 P78417 1
Cholesterol biosynthesis 0.6598376697665067 1.6698053249816456 0.0949578865030118 1.0 0.7322462621110208 14 Q16850,P37268,P48449 3
Sulfur amino acid metabolism 0.6913794687919813 1.6696034793517012 0.0949978415681906 1.0 0.7322462621110208 10 Q13126,Q99707 2
Condensation of prophase chromosomes 0.7041493691252759 1.6686792138393154 0.0951809707242836 1.0 0.7322462621110208 8 Q01105,P53350 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.7036866661099341 1.6666545568132425 0.0955831138770828 1.0 0.7322462621110208 8 Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q9UJX3 5
Abc family proteins mediated transport 0.5715831882577905 1.6654015366731063 0.0958326730531133 1.0 0.7322462621110208 49 P28070,P49721,P51665,P60900,Q99436,O00231,P28072,P08183,O00487,P55036,P28074,P48556,P49720,P25786,P25788,Q9UBV2,P20618 17
Phase i functionalization of compounds 0.6588514495669808 1.664955186514961 0.0959216967797873 1.0 0.7322462621110208 14 P30837,O43169,Q96DG6,Q16850,P07099 5
Cyclin d associated events in g1 0.6966227516862222 1.6630008603453652 0.0963122632762982 1.0 0.7322462621110208 9 Q13616,P30153,Q00534,P63151,Q13309 5
Tysnd1 cleaves peroxisomal proteins 0.7653599146918554 1.6443855732176076 0.1000965832135847 1.0 0.7322462621110208 5 Q2T9J0 1
Cilium assembly 0.5884552956747102 1.643646091406186 0.1002493273703559 1.0 0.7322462621110208 56 O43924,A6NIH7,Q96KP1,O75935,O43805,P53350,O95684,Q9H6D7 8
Recruitment of numa to mitotic centrosomes 0.5238337423935047 1.6227151144814764 0.1046503188497049 1.0 0.7544685290892345 35 O75935,O43805,P53350,O95684,Q9H6D7 5
Signaling by vegf 0.538461578890321 1.6064048779082285 0.108184979819307 1.0 0.7601442009648832 24 Q9UQB8 1
Apc cdc20 mediated degradation of nek2a 0.6697229576209834 1.6025620951599688 0.1090313679552505 1.0 0.7601442009648832 11 Q96DE5,Q16763,Q9UJX4,Q13257,Q9UJX2,Q9UJX3 6
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.6697229576209834 1.6025620951599688 0.1090313679552505 1.0 0.7601442009648832 11 Q96DE5,Q16763,Q9UJX4,Q13257,Q9UJX2,Q9UJX3 6
Interleukin 12 signaling 0.5372617637926748 1.5986977584891418 0.109887775922282 1.0 0.7603792333918713 24 P14174,P78417,Q13126,P52597 4
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6927433943852355 1.5731633779425491 0.115680992775089 1.0 0.7941650817092124 6 P09884,P30153,P49643,Q14181 4
Activation of the pre replicative complex 0.5807723451246605 1.5686763449300722 0.1167233731892491 1.0 0.7941650817092124 20 Q14181,P09884,Q14566,Q9NRF9,P33991,P25205,P33993,P56282,O43913,P49643,Q9NR33,P27694,Q9UJA3,Q9Y619,P49736 15
Regulation of plk1 activity at g2 m transition 0.5159521636098671 1.5675749824936709 0.1169803543925795 1.0 0.7941650817092124 35 Q13616,P30153,O75935,P63208,O43805,Q68CZ6,P53350,O95684,Q9H6D7 9
Signaling by cytosolic fgfr1 fusion mutants 0.6810357780281311 1.5671597734748814 0.1170773504625781 1.0 0.7941650817092124 8 O95684,O15164,Q92614 3
Mitotic g1 phase and g1 s transition 0.6223727496518328 1.5584569890280808 0.1191249562594849 1.0 0.7962867221811202 73 Q15008,P25789,Q14181,P09884,P11802,P25205,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,Q14566,P49721,Q13616,P56282,P30153,Q9UJA3,P49720,P17980,P51665,P60900,Q99436,Q9NR33,Q00534,P31350,P63151,P25788,P49736,P28066,P33991,O00487 36
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.5554171487948619 1.5554896009225117 0.1198295093364274 1.0 0.7971267360205826 22 P14174,P78417,Q13126,P52597 4
Hdr through homologous recombination hrr 0.529969630647608 1.5517693599654636 0.1207174197923244 1.0 0.7991725339136092 24 P41440,P56282,Q14191,Q9UQ84,P40938,P28340,P35249 7
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.7408128080896831 1.543997951948376 0.1225888287751675 1.0 0.8038324629685986 5 Q15067,O95864 2
Tp53 regulates transcription of cell cycle genes 0.6405603888056615 1.5349638504053815 0.1247927079323061 1.0 0.8067584921257537 13 P30307,O95628 2
Sphingolipid de novo biosynthesis 0.6605207821235181 1.5288891944155558 0.126291915444866 1.0 0.8126353624653297 10 P27544,Q06136 2
Tcf dependent signaling in response to wnt 0.5705174589683235 1.522729805376167 0.1278263178957872 1.0 0.8161082140044381 56 O00231,P28072,P55036,P28074,P48556,P25786,P20618,P28070,P49721,P30153,P49720,P51665,P60900,Q99436,Q13363,O14980,P25788,Q16537,Q9UBL3,O00487 20
G alpha 12 13 signalling events 0.6734365660337269 1.4906852278212963 0.1360441562413821 1.0 0.8449109774675758 6 O75116,Q14344 2
Synthesis of dna 0.6326471378402004 1.4882024908059053 0.1366975005884081 1.0 0.8449109774675758 81 P09884,P25789,Q15008,Q14181,P25205,Q96DE5,P33993,O00231,P28072,P63208,P28074,P55036,P48556,P25786,Q9UJX3,P20618,Q13309,P28070,Q14566,P49721,Q13616,P41440,P56282,Q9UJX4,Q9UJA3,P62195,P49720,P40938,P17980,P28340,P35249,P60900,Q99460,P51665,Q99436,Q9NR33,Q9BRT9,Q9UJX6,P25788,O43242,P49736,P28066,P33991,P18858,Q16763,Q9UJX2,O00487 47
Nephrin family interactions 0.6681270875569432 1.4876994496142104 0.1368301728215464 1.0 0.8449109774675758 7 Q13813,P12814,O43707,P46940,O14936 5
Metabolism of cofactors 0.7246982473974093 1.4777848084498333 0.139465385827245 1.0 0.8565100614703312 5 O75874 1
Irs mediated signalling 0.7759632272140428 1.466434413043994 0.1425299768937771 1.0 0.8612978083853747 4 P62993,Q8NEB9 2
Inlb mediated entry of listeria monocytogenes into host cell 0.6672855442580897 1.4643217355285212 0.1431060610745111 1.0 0.8612978083853747 6 O14964 1
Deadenylation of mrna 0.6076706907929956 1.4515019175123012 0.1466401486826112 1.0 0.877928194504155 15 Q9H9A5,Q9HBH5,O95628,Q9UIV1,P23588 5
Estrogen dependent nuclear events downstream of esr membrane signaling 0.7693977335009512 1.440398891065812 0.1497545772447566 1.0 0.884308732964019 4 O14980 1
Assembly and cell surface presentation of nmda receptors 0.6346799618234812 1.4388535586665705 0.1501920179788727 1.0 0.884308732964019 11 P07196,Q13555,Q9BVA1,Q9BUF5,P04350,Q15334,Q14168,O14936 8
Mecp2 regulates transcription of neuronal ligands 0.7678770376776687 1.4343656731989332 0.1514679381154304 1.0 0.884308732964019 4 Q96ST3 1
Regulation of lipid metabolism by pparalpha 0.5861871862080912 1.430557354513224 0.1525571169947337 1.0 0.884308732964019 17 P37268,Q96ST3,Q15067,P11310,P23786 5
Fcgamma receptor fcgr dependent phagocytosis 0.4723306877476663 1.4300544424293968 0.1527013942089907 1.0 0.884308732964019 27 Q9UQB8,O43865 2
Hdr through single strand annealing ssa 0.6112890491340264 1.4291133420452642 0.1529716593404195 1.0 0.884308732964019 14 Q9UQ84,P40938,Q14191 3
Homologous dna pairing and strand exchange 0.6112890491340264 1.4291133420452642 0.1529716593404195 1.0 0.884308732964019 14 Q9UQ84,P40938,Q14191 3
Fgfr1 mutant receptor activation 0.644161598152229 1.427326921385697 0.1534856842254179 1.0 0.884308732964019 9 O95684,O15164,Q92614 3
Beta oxidation of decanoyl coa to octanoyl coa coa 0.7095205482294249 1.4152397346873025 0.1569982179942308 1.0 0.8875567064125313 5 P11310,Q16836 2
Beta oxidation of octanoyl coa to hexanoyl coa 0.7095205482294249 1.4152397346873025 0.1569982179942308 1.0 0.8875567064125313 5 P11310,Q16836 2
Ub specific processing proteases 0.5792913475656164 1.4149319703879242 0.1570884432057193 1.0 0.8875567064125313 65 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,O60493,P62195,P49720,Q15388,P17980,P51665,Q99460,P60900,Q99436,Q93009,Q86UV5,P25788,O43242,Q96K76,P28066,P14735,P45974,P25787,P51784,Q96FW1,O14964,O00487 35
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.6528682749757875 1.4023878314735263 0.1607994650945698 1.0 0.8951246179447846 6 P11310,Q16836 2
Striated muscle contraction 0.7050855316926736 1.3969364677205378 0.1624326770091082 1.0 0.8951246179447846 5 Q9NYL9,P08670 2
Carnitine metabolism 0.7043766665622471 1.3940100044923798 0.1633145835543246 1.0 0.8951246179447846 5 O43772 1
Rna polymerase iii transcription termination 0.6420673985314084 1.3738809648443582 0.169478640021035 1.0 0.9082499902006494 7 P52434,P05455,P19388 3
Ras activation upon ca2 influx through nmda receptor 0.6972159576261195 1.3644342463250396 0.1724309356867293 1.0 0.9097218331058476 5 Q14168,P07196 2
Long term potentiation 0.6972159576261195 1.3644342463250396 0.1724309356867293 1.0 0.9097218331058476 5 Q14168,P07196 2
Unblocking of nmda receptors glutamate binding and activation 0.6972159576261195 1.3644342463250396 0.1724309356867293 1.0 0.9097218331058476 5 Q14168,P07196 2
Negative regulation of nmda receptor mediated neuronal transmission 0.6972159576261195 1.3644342463250396 0.1724309356867293 1.0 0.9097218331058476 5 Q14168,P07196 2
Dna replication 0.6213480128417925 1.3476092766587875 0.1777840853216918 1.0 0.9284939696386444 85 P09884,P25789,Q15008,Q14181,P25205,Q96DE5,P33993,O00231,P28072,P63208,P28074,P55036,P48556,P25786,Q9UJX3,P20618,Q13309,P28070,Q14566,P49721,Q13616,P41440,P56282,Q9UJX4,Q9UJA3,P62195,P49720,P40938,P17980,P28340,P35249,P60900,Q99460,P51665,Q99436,Q9NR33,Q9BRT9,Q9UJX6,P25788,O43242,P49736,P28066,P33991,P18858,Q16763,Q9UJX2,O00487 47
Rab regulation of trafficking 0.4754738657504217 1.3448112283357028 0.1786862033073644 1.0 0.9284939696386444 32 P50395 1
Mitotic g2 g2 m phases 0.6170333593670794 1.3359139102108102 0.1815774137804879 1.0 0.933219057828986 84 O00231,P28072,O75935,P63208,P28074,P55036,P48556,P25786,O95684,P20618,P30307,P28070,P49721,Q13616,P30153,Q9BVA1,Q9Y570,P49720,Q68CZ6,Q9H6D7,P60900,P51665,Q99436,O43805,O14980,P63151,P25788,Q15691,P53350,O00487 30
Phosphorylation of the apc c 0.6113609670263482 1.3291475034131912 0.1837993106506403 1.0 0.9395442030205906 11 Q96DE5,Q16763,Q9UJX4,Q9UJX2,P53350,Q9UJX3 6
Regulation of mecp2 expression and activity 0.6163575291149138 1.3254615428764522 0.185018116518927 1.0 0.9395442030205906 10 Q14739,Q96ST3 2
Carboxyterminal post translational modifications of tubulin 0.632212011118364 1.3133760220073774 0.1890562731484899 1.0 0.9395442030205906 6 Q14166,Q9BVA1,P04350,Q9BUF5 4
Mapk family signaling cascades 0.6128481326832316 1.3085334422931816 0.1906924392665261 1.0 0.9395442030205906 84 P25789,O43924,O00231,P28072,O60725,P28074,P55036,P48556,P25786,P20618,P28070,P49721,P30153,Q13153,P49720,P17980,P49354,P60900,P51665,Q99436,P36404,Q96S59,Q06124,Q9HCE1,O14980,P25788,Q16537,P07196,Q14168,P62993,Q99956,O00487 32
Rhobtb gtpase cycle 0.4583888263738543 1.3079443308070051 0.1908921918686927 1.0 0.9395442030205906 28 Q5VTR2,Q16543,Q9NYL9,P61201,Q12792,O43396,P12814,P08670,P38159,O75116 10
Pten regulation 0.5437661241395687 1.2668535507838363 0.2052076599820571 1.0 0.960932665525443 60 Q15008,P25789,Q13200,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P28070,P49721,Q9UNE7,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q93009,Q9HC52,Q9HCE1,P25788,O43242,P28066,P25787,O00487,Q92769 29
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.6145057685988033 1.2529817825218472 0.2102123366451833 1.0 0.9732004876701088 7 P30307 1
Egfr downregulation 0.6165581085728075 1.2457800678070643 0.212845149138779 1.0 0.9732004876701088 6 O14964 1
Antigen processing ubiquitination proteasome degradation 0.5980333185675083 1.2445586901973538 0.2132940131534977 1.0 0.9732004876701088 82 Q15008,P25789,P68036,Q13200,Q05086,O00231,P28072,Q9UIQ6,P63208,P28074,P55036,P48556,P25786,Q9UJX3,P20618,Q96J02,Q13309,Q9C0C9,P28070,P49721,Q13616,Q9UBS8,P55786,Q9UNE7,Q9UJX4,P62195,P49720,P17980,P52888,P60900,Q99460,P51665,P19474,Q99436,Q9UJX6,Q9Y4B6,P25788,O43242,P28066,P25787,Q16763,Q92990,Q96BH1,Q9UJX2,Q8TBC4,O00487 46
Neddylation 0.5561126792320222 1.24155053473257 0.2144024419973713 1.0 0.9732004876701088 66 Q15008,P25789,Q9NV06,Q13200,Q92905,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q13309,P28070,P49721,Q13616,Q9H0A8,P62195,P49720,Q5TAQ9,P17980,P51665,Q99460,P60900,Q99436,Q99627,Q16531,P25788,O43242,P28066,P25787,Q9BW61,P61201,Q8TBC4,O00487 36
Rna polymerase iii transcription initiation from type 3 promoter 0.6152966946516212 1.2403302537344845 0.2148532667042215 1.0 0.9732004876701088 6 P52434,P19388 2
Rna polymerase iii chain elongation 0.6152966946516212 1.2403302537344845 0.2148532667042215 1.0 0.9732004876701088 6 P52434,P19388 2
Suppression of phagosomal maturation 0.6083436710523976 1.2259145942558851 0.2202308161560804 1.0 0.9790596620192632 7 O14964 1
G2 m checkpoints 0.5758690244338066 1.216257891823561 0.2238866966875812 1.0 0.9790596620192632 75 P25789,O00231,P28072,P28074,P48556,P55036,P25786,P20618,P30307,P28070,Q14566,P49721,Q9UJA3,Q9UQ84,P49720,P40938,P35249,P51665,P60900,Q99436,Q14191,P25788,P49736,O00487 24
Tgf beta receptor signaling activates smads 0.6006142619798642 1.2094975554185383 0.2264717496885815 1.0 0.9790596620192632 8 O14980,Q9UNE7 2
Cellular response to chemical stress 0.5668830064422367 1.208173962879921 0.2269803546833546 1.0 0.9790596620192632 72 O00231,P28072,Q96ST3,P63208,P55036,P28074,P25786,Q86X55,P20618,Q13309,P28070,P49721,Q13616,Q99757,P49720,Q9Y6N1,P51665,P60900,P30519,P25788 20
Regulation of bach1 activity 0.8635590336849265 1.2024356568399508 0.2291947812376111 1.0 0.9790596620192632 3 Q13616,Q13309 2
Signaling by tgfb family members 0.5170165926054899 1.200270030700434 0.2300344850412317 1.0 0.9790596620192632 20 Q9UPN9,O14980,Q9UNE7,O75909 4
S phase 0.6108182573136214 1.1978996576697742 0.2309560830568242 1.0 0.9790596620192632 90 P09884,P25789,Q15008,Q14181,P11802,P25205,Q96DE5,P33993,O00231,P28072,P63208,P28074,P55036,P48556,P25786,Q7Z5K2,Q9UJX3,P20618,Q13309,P28070,Q14566,P49721,Q13616,P41440,P56282,Q9UJX4,Q9UJA3,P62195,P49720,P40938,P17980,P28340,P35249,P60900,Q99460,P51665,Q99436,Q9NR33,Q9BRT9,Q9UJX6,P25788,O43242,P49736,P28066,P33991,P18858,Q16763,Q8WVM7,Q9UJX2,O00487 50
Phenylalanine and tyrosine metabolism 0.7082774619546726 1.197586617568341 0.2310779884940164 1.0 0.9790596620192632 4 P16930,P61457 2
Vitamin b5 pantothenate metabolism 0.705241660993881 1.1855397669126104 0.2358041012390459 1.0 0.9802354770709611 4 Q13057,P49327,Q9NRN7 3
Regulation of cholesterol biosynthesis by srebp srebf 0.5045736140580664 1.1834487693372004 0.2366313388124028 1.0 0.9802354770709611 21 P37268,Q16850,Q9Y6B6,Q86X55,P48449 5
Formation of tc ner pre incision complex 0.440513948589531 1.178944957385086 0.2384200942737422 1.0 0.9802354770709611 28 P52434,Q92905,Q9UNP9,Q93009,P61201,Q99627,P23193,P19388 8
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.5846650061030587 1.178677997033887 0.2385264203484769 1.0 0.9802354770709611 10 Q16763,Q93009,P68036,Q9NPD8 4
Downregulation of erbb2 signaling 0.7028289399001304 1.175968901748957 0.2396073032938388 1.0 0.9802354770709611 4 Q9UNE7 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6515623665942392 1.1756242765618805 0.2397450500986082 1.0 0.9802354770709611 5 P62993,Q8NEB9 2
Dna replication initiation 0.59299370252123 1.1754421796931402 0.2398178568182691 1.0 0.9802354770709611 8 P09884,Q14181,P56282,P49643,Q9NR33 5
Sensory processing of sound by outer hair cells of the cochlea 0.5787230441306834 1.1750774266842567 0.2399637407450567 1.0 0.9802354770709611 11 Q14651,Q00013,Q12792,Q13813,P15311,O14936 6
Insulin receptor signalling cascade 0.5998211029251515 1.1734641504797063 0.2406097249455228 1.0 0.9802354770709611 6 P62993,Q8NEB9 2
Diseases of dna repair 0.5821800883987944 1.167164747103032 0.2431438444236415 1.0 0.9848288470304222 10 Q9UQ84 1
Signaling by tgf beta receptor complex 0.5191198043496401 1.1601651203850378 0.2459815849689193 1.0 0.9858987229106224 19 Q9UPN9,O14980,Q9UNE7,O75909 4
Spry regulation of fgf signaling 0.6467857645787352 1.155886370064995 0.2477276384365108 1.0 0.9858987229106224 5 P62993,P30153 2
Negative regulation of fgfr2 signaling 0.6467857645787352 1.155886370064995 0.2477276384365108 1.0 0.9858987229106224 5 P62993,P30153 2
Negative regulation of fgfr3 signaling 0.6467857645787352 1.155886370064995 0.2477276384365108 1.0 0.9858987229106224 5 P62993,P30153 2
Negative regulation of fgfr1 signaling 0.6467857645787352 1.155886370064995 0.2477276384365108 1.0 0.9858987229106224 5 P62993,P30153 2
Negative regulation of fgfr4 signaling 0.6467857645787352 1.155886370064995 0.2477276384365108 1.0 0.9858987229106224 5 P62993,P30153 2
Signaling by fgfr1 in disease 0.5775385399788696 1.1456632784129557 0.2519345036288358 1.0 0.9903098986766448 10 O95684,O15164,Q92614 3
Translation of replicase and assembly of the replication transcription complex 0.5900284298704042 1.145467097878364 0.2520157173471657 1.0 0.9903098986766448 7 Q9UQN3,Q8WUX9,Q8NEB9 3
Post chaperonin tubulin folding pathway 0.5747277579233311 1.1326461935757175 0.2573628616909431 1.0 0.995473765585474 10 Q99426,P36404,Q9BVA1,Q9BUF5,P04350,Q15813 6
Polo like kinase mediated events 0.8433948310567478 1.1276828703053383 0.2594538744616592 1.0 0.9975486357960524 3 P30307 1
G2 m dna damage checkpoint 0.4389019236087992 1.125005429238949 0.2605867336227685 1.0 0.9975486357960524 30 P30307,Q9UQ84 2
Prolactin receptor signaling 0.842123171146649 1.1229830369658194 0.2614446988384609 1.0 0.9975486357960524 3 P63208,Q13616 2
Endosomal sorting complex required for transport escrt 0.5502090426623639 1.122802307486574 0.2615214651578612 1.0 0.9975486357960524 14 Q99816,Q9NZZ3,Q8WUX9,Q9NZ09,Q9UQN3,O14964 6
Telomere c strand synthesis initiation 0.633736466102352 1.1020319725513894 0.2704477719180556 1.0 1.0 5 P09884,P49643,Q14181 3
Transcriptional regulation by ventx 0.5625890633118743 1.0989233050055776 0.27180152041377 1.0 1.0 11 Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q9HCE1,Q9UJX3 6
Apc c cdc20 mediated degradation of cyclin b 0.5662008278594834 1.0931813276391462 0.2743141936576863 1.0 1.0 10 Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q9UJX3 5
O linked glycosylation 0.5770040014574285 1.0749967081008844 0.2823762021574563 1.0 1.0 6 Q10472,Q9UHI8 2
Gap junction assembly 0.6262003170674284 1.0709917986934785 0.2841731172820441 1.0 1.0 5 Q9BVA1,P04350,Q9BUF5 3
Transport of connexons to the plasma membrane 0.6262003170674284 1.0709917986934785 0.2841731172820441 1.0 1.0 5 Q9BVA1,P04350,Q9BUF5 3
Prevention of phagosomal lysosomal fusion 0.6752696579097475 1.0669577846698808 0.2859908993380222 1.0 1.0 4 O14964 1
Vitamin c ascorbate metabolism 0.8259993154166194 1.0635741121493825 0.2875216750456841 1.0 1.0 3 P78417 1
Ca2 pathway 0.6736283835139008 1.060489512392251 0.2889219586960445 1.0 1.0 4 P09471,Q9UBI6 2
Signaling by notch 0.5070314920386965 1.054395009389226 0.2917021061868903 1.0 1.0 58 Q15008,P25789,Q9H488,Q13200,O00231,P28072,P63208,P28074,P48556,P55036,P25786,P20618,Q96J02,P28070,P49721,Q13616,P62195,P49720,P17980,P16220,P51665,Q99460,P60900,Q99436,Q9HCE1,P25788,O43242,P28066,P25787,Q9UBV2,O00487,Q92769 32
Deubiquitination 0.5634318326141657 1.0505959047566975 0.2934442227412019 1.0 1.0 80 Q15008,P25789,Q15018,Q13200,O00231,P28072,Q8NB78,P28074,P55036,P48556,P25786,P20618,Q13309,P28070,P49721,O60493,P62195,P49720,Q15388,P17980,P60900,Q99460,P51665,Q99436,Q93009,Q86UV5,O95630,P25788,O43242,O15294,Q96K76,P28066,P14735,P45974,P25787,P51784,Q96FW1,Q9Y5K5,O14964,O00487 40
Transcriptional regulation by runx1 0.5184088728244004 1.0416426145039863 0.2975774036261092 1.0 1.0 63 Q15008,P25789,O14497,Q13200,O00231,P28072,Q96ST3,P28074,P48556,P55036,P25786,P17931,P20618,Q96J02,P28070,P49721,P62195,P49720,P17980,P51665,Q99460,P60900,Q99436,Q8TAQ2,Q06124,Q9HC52,Q9HCE1,Q00534,P25788,O43242,P28066,P25787,Q9UBL3,Q86U86,O00487 35
Platelet sensitization by ldl 0.5691243591560685 1.0410749695137616 0.2978407554279083 1.0 1.0 6 Q16537,P30153 2
Biological oxidations 0.466596017326863 1.0389024022267797 0.2988501290676979 1.0 1.0 44 Q9NUJ1,P30837,Q96KP4,O43169,O15217,Q96DG6,Q16850,P78417,P07099,Q99707,O00170 11
Dag and ip3 signaling 0.5603867546263419 1.0300019628208998 0.3030090841754562 1.0 1.0 8 O43865 1
Telomere c strand lagging strand synthesis 0.4683659569596543 1.022355655894395 0.3066126003313103 1.0 1.0 22 Q14181,P09884,P41440,Q14191,P40938,P28340,P35249 7
Cdc42 gtpase cycle 0.4142028937164719 1.0099530676262969 0.3125177759787116 1.0 1.0 27 Q9UQB8 1
Negative regulation of met activity 0.5562266831613875 0.99745998059703 0.3185412896538699 1.0 1.0 7 O14964 1
Regulation of ifng signaling 0.6075582920907577 0.9944881224467764 0.3199852850984537 1.0 1.0 5 O75925 1
Budding and maturation of hiv virion 0.5261231144225721 0.9741806915849734 0.3299668299391138 1.0 1.0 13 Q99816,Q9NZZ3,Q8WUX9,Q9NZ09,Q9UQN3,Q9Y3E7,Q9H9H4,Q8WUM4 8
Assembly of the hiv virion 0.7985709424974459 0.9634765369468588 0.335308433298551 1.0 1.0 3 Q99816,Q9NZ09 2
Regulation of runx1 expression and activity 0.7978904389247883 0.9610117172038904 0.3365462763951259 1.0 1.0 3 Q00534,Q06124 2
Rac3 gtpase cycle 0.417211652186524 0.948966273398088 0.342637765728937 1.0 1.0 31 Q9UQB8 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4962885815686804 0.948063787473504 0.3430969820361169 1.0 1.0 17 P61758,Q99471,Q9BVA1,Q9UHV9,P04350,O15212,Q9BUF5,Q13885,P78371 9
Metabolism of nitric oxide nos3 activation and regulation 0.5955703914300648 0.9455728681527326 0.3443664882223429 1.0 1.0 5 Q9Y314,P35270 2
Transcriptional regulation by mecp2 0.5137153345418646 0.940297370314598 0.3470650480972481 1.0 1.0 14 Q14739,Q96ST3 2
Separation of sister chromatids 0.5771404221238134 0.933560482521039 0.3505306577957974 1.0 1.0 93 Q15008,P25789,Q96DE5,Q13200,P61289,O00231,O43237,P28072,Q13257,P28074,P55036,P48556,Q9HBM1,Q7Z5K2,P25786,Q9UJX3,P20618,P28070,P49721,Q9P258,Q12769,P30153,Q9UJX4,Q9BVA1,P62195,P49720,P17980,P57740,P60900,Q99460,P51665,Q99436,Q9UJX6,O14980,O00139,P25788,O43242,P28066,Q16537,P25787,Q15691,Q16763,Q8WVM7,O43264,Q9UJX2,Q96EE3,P53350,O00487 48
Heme signaling 0.5398203045453217 0.9156441858576696 0.3598535480622542 1.0 1.0 6 P16220,O14980 2
Mitotic spindle checkpoint 0.4515389647777174 0.9155920020593546 0.359880927778875 1.0 1.0 45 P57740,Q16537,Q9P258,Q96DE5,Q15691,Q16763,Q12769,P30153,Q9UJX4,O14980,Q13257,O43264,Q9UJX2,Q96EE3,P53350,Q9HBM1,Q9UJX3,O00139 18
Ctla4 inhibitory signaling 0.5355015904350195 0.9074479618542416 0.3641699562246172 1.0 1.0 7 Q06124,Q16537,P30153 3
Activation of gene expression by srebf srebp 0.5008943537470251 0.9050356083655368 0.3654465230921135 1.0 1.0 15 Q16850,Q86X55,P37268,P48449 4
Mitotic telophase cytokinesis 0.5203922225824513 0.9010201854835737 0.367577587334893 1.0 1.0 11 Q7Z5K2 1
Signaling by wnt 0.5351835983298928 0.8987982450055939 0.3687601350760809 1.0 1.0 78 Q15008,P25789,P53680,Q13200,P61289,O00231,P28072,P63208,P28074,P55036,P48556,P25786,Q96QK1,P20618,Q9UBI6,P28070,P49721,Q13616,P30153,O60493,P62195,P49720,P17980,P60900,Q99460,P51665,Q99436,Q13363,Q9HCE1,O14980,P25788,O94973,O43242,P09471,P28066,Q16537,P25787,Q9UBL3,O00487 39
Hsf1 activation 0.5138230184966794 0.8909529367280566 0.3729544191198406 1.0 1.0 12 Q02790,P07900,P0DMV9,Q15185,P62258,P27694,Q92598,P15927 8
Retrograde neurotrophin signalling 0.5253390572724853 0.8889594360080203 0.3740248806104449 1.0 1.0 9 Q9UQ16,P09496,P53680,O94973 4
Listeria monocytogenes entry into host cells 0.5271549876300193 0.8831170423904343 0.3771730370993418 1.0 1.0 8 O14964 1
Signaling by erbb2 0.5218939147882264 0.8735772118111096 0.3823485408075271 1.0 1.0 9 P62993,Q9UNE7,P07947 3
Sema4d induced cell migration and growth cone collapse 0.5774250864532615 0.8721022661727135 0.3831525899851906 1.0 1.0 5 O75116,P35579 2
Signaling by erbb4 0.5287297847249445 0.8686059672080516 0.3850626895139017 1.0 1.0 6 P62993,P61201 2
Interconversion of nucleotide di and triphosphates 0.4665110773196733 0.8641158891883299 0.3875242312775366 1.0 1.0 19 P15531,Q9Y3D8,Q9H773,P22392,Q9NRF8,P17812 6
E2f mediated regulation of dna replication 0.5120306969486194 0.8622237911963838 0.3885643800827871 1.0 1.0 11 P09884,Q14181,O43913,P30153,P49643,Q9UJA3,P30154 7
Signaling by hippo 0.574040080445118 0.8584875118373928 0.3906233233315888 1.0 1.0 5 Q4VCS5,P62258,Q07157 3
Regulated necrosis 0.4721125068534255 0.8554685688097501 0.3922917976798814 1.0 1.0 18 P41440,Q8WUX9,Q9UNE7,Q9UQN3,Q9Y3E7,O15294 6
Rac1 gtpase cycle 0.4231988163728751 0.852723877874075 0.3938124461363206 1.0 1.0 38 Q9UQB8,Q14739 2
Glutathione conjugation 0.4893178954114026 0.8465741129188795 0.3972325480975558 1.0 1.0 15 O15217 1
Abortive elongation of hiv 1 transcript in the absence of tat 0.4986334202512107 0.8409154154716038 0.400395321754547 1.0 1.0 13 P52434,Q9H3P2,P19388,O00267,P18615 5
Signaling by fgfr in disease 0.4617984259163435 0.8379217864486905 0.402074631955988 1.0 1.0 19 O95684,O15164,P62993,Q92614 4
Rho gtpases activate rocks 0.5072138926441817 0.8229408117809635 0.4105416527806054 1.0 1.0 10 O75116,P35580,P35579,Q13153 4
Translesion synthesis by polk 0.507802132729378 0.811020595682084 0.4173538433229065 1.0 1.0 9 P40938,P41440 2
Small interfering rna sirna biogenesis 0.7555833776822858 0.8100977181568624 0.4178840156479979 1.0 1.0 3 Q15631 1
Negative regulation of mapk pathway 0.5004188057111962 0.8086997797673738 0.4186878548914399 1.0 1.0 11 Q99956,P30153 2
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5142915268591575 0.8078703699971151 0.4191652099559069 1.0 1.0 6 P30153 1
Beta catenin phosphorylation cascade 0.5142915268591575 0.8078703699971151 0.4191652099559069 1.0 1.0 6 P30153 1
Signaling by ctnnb1 phospho site mutants 0.5142915268591575 0.8078703699971151 0.4191652099559069 1.0 1.0 6 P30153 1
Ncam signaling for neurite out growth 0.5119035034409406 0.7978887081932771 0.4249350766947524 1.0 1.0 6 P16220 1
Mecp2 regulates neuronal receptors and channels 0.50586963829333 0.7904403001495026 0.4292706744360091 1.0 1.0 8 Q96ST3 1
Heme biosynthesis 0.5100262309181552 0.7900559132581724 0.4294951152830388 1.0 1.0 6 P36551 1
Signaling by wnt in cancer 0.5056825695527727 0.7896324835662952 0.4297424318587843 1.0 1.0 8 Q13363,P30153 2
Phase ii conjugation of compounds 0.3889902285541652 0.7888539562077546 0.4301973694926158 1.0 1.0 29 Q9NUJ1,P78417,Q99707,O15217 4
Late endosomal microautophagy 0.4910976102413195 0.7840383615122686 0.433017601193157 1.0 1.0 12 Q99816,Q8WUX9,Q9NZ09,Q9UQN3,Q9Y3E7,P08670 6
Oncogene induced senescence 0.5070864047277024 0.7778153359280471 0.4366778856436157 1.0 1.0 6 Q00534,Q9HCE1 2
Regulation of tp53 activity through phosphorylation 0.3816155582445107 0.7764942679399522 0.4374572039690418 1.0 1.0 27 Q92804,Q9UQ84,Q14191 3
Interleukin 3 interleukin 5 and gm csf signaling 0.5044612277025937 0.7746152748736786 0.438567028605104 1.0 1.0 7 Q06124,P62993 2
Transcription of the hiv genome 0.4094106144028404 0.7688297394134225 0.4419943916904838 1.0 1.0 24 P52434,P19447,Q8IXH7,O43148,Q92804,Q9H3P2,P23193,P19388,O75909,P19387,O00267,P18615 12
Ripk1 mediated regulated necrosis 0.4911418430095574 0.7662909558151618 0.4435031985231075 1.0 1.0 11 P41440,Q16543,Q9UNE7,Q8WUM4,O15294 5
Fbxw7 mutants and notch1 in cancer 0.8632653061224469 0.761176987045162 0.4465513617051115 1.0 1.0 2 Q13616 1
Map3k8 tpl2 dependent mapk1 3 activation 0.8632653061224469 0.761176987045162 0.4465513617051115 1.0 1.0 2 Q13616 1
Aquaporin mediated transport 0.5490805633792822 0.759214121458027 0.4477244799604198 1.0 1.0 5 Q9UBI6 1
Platelet homeostasis 0.4925742544129104 0.7573039463148192 0.4488677871858737 1.0 1.0 10 Q16537,P30153,Q9UBI6 3
Neurotransmitter release cycle 0.50114079882867 0.7531604925350001 0.4513534769044338 1.0 1.0 6 O14936,P11142 2
Sensory processing of sound 0.4687890128711814 0.7441266938441957 0.4567998314352297 1.0 1.0 15 Q14651,Q00013,Q12792,Q13813,P15311,P47756,O14936,P52907 8
Intracellular signaling by second messengers 0.5134131954579344 0.7428770570582989 0.457556117211467 1.0 1.0 79 Q15008,P25789,Q13200,O00231,Q13555,P28072,P28074,P55036,P48556,P25786,P20618,P28070,P49721,P30153,Q9UNE7,P62195,P49720,P17980,P16220,P60900,Q99460,P51665,Q99436,Q93009,Q8TBX8,Q06124,Q9HC52,Q9HCE1,O43865,P25788,O43242,P28066,Q16537,P25787,P62993,O00487,Q92769 37
Dual incision in tc ner 0.3994854401500986 0.7268574468090077 0.4673132872402932 1.0 1.0 36 P52434,P41440,P56282,Q9UNP9,Q93009,Q9NR33,P23193,P40938,P19388,P28340,P35249 11
Rhobtb1 gtpase cycle 0.4409900859712405 0.7234757511766405 0.4693876466200533 1.0 1.0 19 Q5VTR2,P61201,O43396,P08670,P38159,O75116 6
Role of phospholipids in phagocytosis 0.7289547645633448 0.718092459756767 0.472700279082024 1.0 1.0 3 O43865 1
Polymerase switching 0.4675345487021487 0.7141029200147331 0.4751635404836296 1.0 1.0 14 Q14181,P41440,P40938,P28340,P35249 5
Constitutive signaling by overexpressed erbb2 0.7273208804904683 0.7125400095351786 0.4761304451420147 1.0 1.0 3 P62993 1
Gab1 signalosome 0.7232143531664171 0.6986366924440617 0.4847791068551939 1.0 1.0 3 P62993 1
Flt3 signaling 0.7232143531664171 0.6986366924440617 0.4847791068551939 1.0 1.0 3 P62993 1
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.4843828361481525 0.6986052906749444 0.4847987364277899 1.0 1.0 8 Q9UPN9 1
Metabolism of porphyrins 0.4787817258668472 0.6963142074862493 0.4862320775930326 1.0 1.0 10 P30519,P36551 2
Signaling by flt3 itd and tkd mutants 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr2 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Frs mediated fgfr1 signaling 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr1 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Stat5 activation 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Frs mediated fgfr4 signaling 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr3 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Frs mediated fgfr3 signaling 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr4 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Frs mediated fgfr2 signaling 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Tie2 signaling 0.8418367346938762 0.6915419783953543 0.4892250097658714 1.0 1.0 2 P62993 1
Termination of translesion dna synthesis 0.4348714398745255 0.6902883701519218 0.4900128599821614 1.0 1.0 19 P41440,P56282,P40938,P28340,P35249 5
Fcgr3a mediated il10 synthesis 0.4820167623403386 0.6886240682457748 0.4910598709503229 1.0 1.0 8 P16220,O43865 2
Regulation of insulin secretion 0.469651131266857 0.6850895795116335 0.4932873954596575 1.0 1.0 12 O43865 1
Diseases associated with o glycosylation of proteins 0.8397959183673438 0.6850144018622152 0.4933348330283802 1.0 1.0 2 Q9UHI8 1
Hiv elongation arrest and recovery 0.4399275667288509 0.6834814397347069 0.4943026743602365 1.0 1.0 18 P52434,Q9H3P2,P23193,O75909,P19388,O00267,P18615 7
Beta oxidation of butanoyl coa to acetyl coa 0.7184508281579114 0.6826048818080127 0.494856548480594 1.0 1.0 3 Q16836 1
Thrombin signalling through proteinase activated receptors pars 0.5725100525473734 0.673811228428088 0.5004313353048175 1.0 1.0 4 Q14344 1
Polymerase switching on the c strand of the telomere 0.4488657636545448 0.6711449743724645 0.5021281785301626 1.0 1.0 16 P09884,Q14181,P41440,P40938,P28340,P35249 6
Metabolic disorders of biological oxidation enzymes 0.5263282512151712 0.6708721786018469 0.5023019612553372 1.0 1.0 5 P48507 1
Pcna dependent long patch base excision repair 0.4294613182020849 0.6611579446765311 0.5085110283183392 1.0 1.0 19 P41440,P56282,P40938,P28340,P35249 5
Trna modification in the nucleus and cytosol 0.473258567635501 0.6609864541613579 0.5086210006034169 1.0 1.0 9 Q08J23,Q9UBP6 2
Leishmania infection 0.3864312758729184 0.6563861965432288 0.5115756695602096 1.0 1.0 35 Q9UQB8,P61160,P62993,O43865,P16220,Q9UBI6 6
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4075355575452176 0.6560516759547345 0.511790875499381 1.0 1.0 22 P41440,P56282,P40938,P28340,P35249 5
G protein mediated events 0.4665955059557882 0.6560160498498918 0.5118137974979104 1.0 1.0 11 O43865 1
Signaling by fgfr4 0.476778449176748 0.6537879607831686 0.5132484239573181 1.0 1.0 6 P62993,P30153 2
Signaling by fgfr3 0.476778449176748 0.6537879607831686 0.5132484239573181 1.0 1.0 6 P62993,P30153 2
Signaling by fgfr1 0.476778449176748 0.6537879607831686 0.5132484239573181 1.0 1.0 6 P62993,P30153 2
Raf independent mapk1 3 activation 0.4764307753007659 0.6523917840384894 0.5141484631351478 1.0 1.0 6 Q99956 1
Flt3 signaling in disease 0.4753671929087224 0.6481249498601939 0.5169041380193897 1.0 1.0 6 P62993,Q92614 2
Thromboxane signalling through tp receptor 0.7077010056238242 0.6468252178521592 0.5177450693368231 1.0 1.0 3 Q14344 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.411722146930809 0.6378842185512162 0.5235490514918788 1.0 1.0 21 P41440,P56282,P40938,P28340,P35249 5
Met activates ptpn11 0.7039675628854272 0.6345350666636252 0.5257316893247226 1.0 1.0 3 P62993 1
Signaling by fgfr2 0.4028058380061542 0.62851149679619 0.5296689176129479 1.0 1.0 22 P52434,P31943,P52597,P30153,Q06124,P62993,P19388 7
Signaling by fgfr 0.4028058380061542 0.62851149679619 0.5296689176129479 1.0 1.0 22 P52434,P31943,P52597,P30153,Q06124,P62993,P19388 7
Translesion synthesis by polh 0.4565766671304836 0.6260165238224286 0.5313041032178223 1.0 1.0 12 P40938,P41440 2
Vxpx cargo targeting to cilium 0.4646769425391248 0.6246763468009928 0.5321835002742361 1.0 1.0 9 Q92538,P18085,Q96KP1,Q9UPT5 4
Linoleic acid la metabolism 0.8183673469387869 0.6176927337413034 0.5367779026883408 1.0 1.0 2 O95864 1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.6964108177920746 0.6098864294676278 0.5419370426270054 1.0 1.0 3 P16220 1
Camk iv mediated phosphorylation of creb 0.6964108177920746 0.6098864294676278 0.5419370426270054 1.0 1.0 3 P16220 1
Lagging strand synthesis 0.4190030645332336 0.605491003346765 0.5448528006665785 1.0 1.0 19 Q14181,P41440,P40938,P28340,P35249 5
Opioid signalling 0.4297500539585149 0.602067273493651 0.5471293577945417 1.0 1.0 17 P30153,O43865 2
Met activates ras signaling 0.5491512383449578 0.5901651309089885 0.5550799467795784 1.0 1.0 4 P62993 1
Notch1 intracellular domain regulates transcription 0.4597732069272559 0.5863554049455837 0.5576367057811444 1.0 1.0 6 P63208,Q13616,Q92769 3
Pyroptosis 0.4577263984763138 0.5823149987182924 0.5603545245179378 1.0 1.0 7 Q9UQN3,Q8WUX9 2
Oncogenic mapk signaling 0.3792300683056444 0.5802899537271275 0.5617191010778138 1.0 1.0 24 O15164,Q9NRY5,Q96PU8,Q99956 4
Sealing of the nuclear envelope ne by escrt iii 0.4421678634042689 0.5770215699274616 0.5639248844525808 1.0 1.0 13 Q8WUX9,Q9BVA1,Q9UQN3,Q9Y3E7,Q9UN37 5
Recognition of dna damage by pcna containing replication complex 0.4169736401846453 0.5649521680374879 0.5721062987672347 1.0 1.0 18 P41440,P56282,P40938,P28340,P35249 5
Dual incision in gg ner 0.3842950584420894 0.5641650279128838 0.5726418259800155 1.0 1.0 23 P41440,P56282,Q9NR33,P40938,Q86WJ1,P28340,P35249 7
Dna damage recognition in gg ner 0.4309603991587929 0.5616045735959423 0.5743854636076575 1.0 1.0 15 Q92905,P61201,Q99627 3
Extra nuclear estrogen signaling 0.4465187935131035 0.5579629349118164 0.5768696944972409 1.0 1.0 10 P16220,O14980 2
Vldlr internalisation and degradation 0.4452053803235248 0.5331046113143003 0.5939611671521345 1.0 1.0 7 P53680,O94973 2
Wnt5a dependent internalization of fzd4 0.4452053803235248 0.5331046113143003 0.5939611671521345 1.0 1.0 7 P53680,O94973 2
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.4452053803235248 0.5331046113143003 0.5939611671521345 1.0 1.0 7 P53680,O94973 2
Resolution of sister chromatid cohesion 0.4123807265726949 0.5322592833995434 0.5945464283352095 1.0 1.0 52 Q16537,Q12769,P30153,Q8WVM7,O43264,Q96EE3,P53350,Q9HBM1,Q7Z5K2,O14980,O00139 11
Ngf stimulated transcription 0.5319859154937703 0.5308438324786423 0.5955270027028559 1.0 1.0 4 P50570,P16220 2
Formation of the early elongation complex 0.4199360622012973 0.5304053893810184 0.5958308901642739 1.0 1.0 16 P52434,Q8IXH7,Q9H3P2,P19388,P19387,O00267,P18615 7
G protein beta gamma signalling 0.4880842269300058 0.5288475858776885 0.596911184227459 1.0 1.0 5 Q9UBI6 1
Rhobtb2 gtpase cycle 0.40197978493571 0.517044344542081 0.6051252035828285 1.0 1.0 19 Q16543,Q9NYL9,Q12792,O43396,P12814,P38159 6
Antigen activates b cell receptor bcr leading to generation of second messengers 0.6669259492791468 0.5169334211176718 0.605202636345979 1.0 1.0 3 O43865 1
Activation of kainate receptors upon glutamate binding 0.6644612968592463 0.5094178416860456 0.6104593729824335 1.0 1.0 3 Q9UBI6 1
Dna damage bypass 0.3672784628796987 0.5082954965682837 0.6112461278194126 1.0 1.0 24 P41440,P56282,P40938,P28340,P35249 5
Ca dependent events 0.4369585652075067 0.5013749992117998 0.616107231398404 1.0 1.0 7 P16220 1
Interferon gamma signaling 0.4248969521241475 0.5007105854733735 0.6165748213542637 1.0 1.0 13 P19474,Q12899,Q06124,O75925 4
Negative regulation of the pi3k akt network 0.4264635177029046 0.4947930232460075 0.620746229645778 1.0 1.0 12 Q16537,P30153,Q8TBX8,P62993 4
Class i mhc mediated antigen processing presentation 0.5299799539118704 0.4882522182320858 0.625371201571304 1.0 1.0 104 Q15008,P25789,P68036,Q13200,Q05086,O00231,P28072,Q9UIQ6,P63208,P28074,P55036,P48556,P25786,Q9UJX3,P20618,Q96J02,Q13309,Q9C0C9,P28070,P49721,Q13616,Q9UBS8,P55786,Q9UNE7,Q9UJX4,P62195,P49720,O95486,P17980,Q9NZ08,P52888,P60900,Q99460,P51665,P19474,Q99436,Q9UBG0,Q9UJX6,Q9Y4B6,P25788,O43242,P28066,P25787,Q16763,Q92990,Q96BH1,Q9UJX2,Q9Y6B6,Q8TBC4,O00487 50
O linked glycosylation of mucins 0.5191531793558423 0.4878799281760068 0.6256348924935302 1.0 1.0 4 Q10472 1
Disorders of transmembrane transporters 0.4579805897095932 0.4756138868340083 0.6343494802011322 1.0 1.0 74 Q15008,P25789,Q13200,P61289,O00231,P28072,P28074,P48556,P55036,P25786,P20618,Q9NRG9,P28070,P49721,Q12769,P62195,P49720,P17980,O00400,P57740,P51665,Q99460,P60900,Q99436,P25788,O43242,P12270,P28066,Q5SRE5,P25787,P11166,Q96EE3,Q9UBV2,O00487 34
Raf activation 0.4260062841187151 0.4677586388538339 0.6399572019069184 1.0 1.0 9 Q16537,P30153 2
Sars cov 1 infection 0.4104285503976493 0.4675311936730326 0.6401198797801553 1.0 1.0 15 Q9UQN3,Q8WUX9,Q10472,Q8NEB9 4
Rhou gtpase cycle 0.4055797082777448 0.4634946814434078 0.643009826244981 1.0 1.0 16 Q9NNW5,Q13177,Q13153,Q13813,Q03001,P62993,O43396,P46940,O14964,Q00610 10
Processing of dna double strand break ends 0.3733864277256568 0.4626231975149269 0.6436344779705645 1.0 1.0 22 Q9UQ84 1
Sumoylation of transcription cofactors 0.4209787081523545 0.4619769519991139 0.644097848698109 1.0 1.0 11 O75925,Q96ST3 2
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3433023848637833 0.459757520875388 0.6456902770131787 1.0 1.0 30 P31689,Q02790,P07900,Q13561,Q13409,P31948,O43237,Q14203,Q9BVA1,P61163,P04350,O75935,Q9BUF5,Q9UJW0,P47756,Q13885,P52907,P11142 18
Fceri mediated ca 2 mobilization 0.5098240874342788 0.4574715664597393 0.6473321348862804 1.0 1.0 4 O43865 1
Signaling by interleukins 0.5088448750429707 0.4574689078422057 0.6473340454061765 1.0 1.0 97 Q13126,O00231,P28072,P63208,P28074,P55036,P48556,P04083,P25786,P20618,P28070,P49721,Q13616,P52597,P30153,P14174,P49720,P08670,P16220,P60900,P51665,Q99436,Q06124,O00170,P25788,P07947,O14979,P78417,P62993,O00487 30
Regulation of tp53 activity 0.3794876802522495 0.4555524578027112 0.6487118371905913 1.0 1.0 44 Q13625,P30153,Q8TBX8,Q14191,Q92804,Q9UQ84 6
Signaling by egfr 0.4205632252982906 0.4525818155197769 0.6508498954452215 1.0 1.0 10 P62993,O14964 2
G beta gamma signalling through cdc42 0.5067411697596051 0.4475854428577518 0.6544524109862466 1.0 1.0 4 Q9UBI6 1
Muscle contraction 0.3492561663051394 0.4462421677556899 0.6554223261712115 1.0 1.0 25 P04083,Q9NYL9,Q13153,O43865,P08670,P06753 6
Nef mediated cd4 down regulation 0.4225183404949564 0.4461176565844029 0.6555122592505567 1.0 1.0 6 P53680 1
Nef mediated cd8 down regulation 0.4225183404949564 0.4461176565844029 0.6555122592505567 1.0 1.0 6 P53680 1
Synthesis of very long chain fatty acyl coas 0.4208700091740565 0.4401990930404963 0.6597929165682359 1.0 1.0 6 Q53GQ0,Q9NZ01 2
Circadian clock 0.4147362107023743 0.4369092799042361 0.6621771416579507 1.0 1.0 11 P16220,Q86X55,Q13616 3
Phenylalanine metabolism 0.6397497120782412 0.4365119655367821 0.6624653196689476 1.0 1.0 3 P61457 1
Interaction between l1 and ankyrins 0.6355903368492611 0.4247063306509826 0.671050768277613 1.0 1.0 3 Q13813,Q12955 2
Attenuation phase 0.4121978385740712 0.4200453597987565 0.674452317529505 1.0 1.0 10 Q02790,P07900,P0DMV9,Q92598,P11142 5
Uptake and actions of bacterial toxins 0.4143100511073108 0.4174595495511935 0.6763423055851843 1.0 1.0 7 P07900,P13639,Q7L0J3,Q8WUM4,P36507,P08238 6
Synthesis of pips at the early endosome membrane 0.4544097605255949 0.4129756414619638 0.6796244603124366 1.0 1.0 5 Q8NEB9 1
Cell cell junction organization 0.4111315327900765 0.4078205421751905 0.6834054311320612 1.0 1.0 8 P19022 1
Fgfr2 alternative splicing 0.3929217545741321 0.4065272242101653 0.6843552578490661 1.0 1.0 16 P52434,P31943,P19388,P52597 4
Pi metabolism 0.3993463637917971 0.4048689910705082 0.6855738128559636 1.0 1.0 14 Q8NEB9,Q8N9F7,Q8TBX8 3
Purine salvage 0.4107056976338969 0.4043234346719858 0.6859748948089062 1.0 1.0 6 P00813,P07741,P55263 3
Metabolism of water soluble vitamins and cofactors 0.3475966834958925 0.4032997383102793 0.686727734229335 1.0 1.0 35 Q9H2D1,P41440,P34896,P78417,P11166,Q99707,Q9NRN7 7
Costimulation by the cd28 family 0.3953741918161916 0.4015671604031655 0.6880026022002907 1.0 1.0 15 Q16537,P30153,Q06124,P62993,P07947 5
Signaling by flt3 fusion proteins 0.4484758290311584 0.3936649262715933 0.6938284394257801 1.0 1.0 5 Q92614 1
Global genome nucleotide excision repair gg ner 0.3554065587875735 0.38722985533591 0.6985860495474585 1.0 1.0 39 P41440,Q92905,P56282,P61201,Q9NR33,Q99627,P40938,Q86WJ1,O75925,P28340,P35249 11
Formation of incision complex in gg ner 0.399971531714091 0.3866938868078473 0.6989828423892439 1.0 1.0 12 P19447,P32780,Q86WJ1,O75925,Q16531 5
Signaling by braf and raf1 fusions 0.3645941225027548 0.3845024956858852 0.7006060465164152 1.0 1.0 21 O15164,O43252,Q53H12,Q13555,Q96PU8,P30086,P46940,Q9NRY5,P51114 9
Homology directed repair 0.3456022367649434 0.3750624563614414 0.7076140177662344 1.0 1.0 36 P41440,P56282,Q14191,Q9UQ84,P40938,P28340,P35249 7
Regulation of signaling by cbl 0.4820690027251768 0.3716449007666077 0.7101572538047765 1.0 1.0 4 P62993 1
Citric acid cycle tca cycle 0.3758441735965402 0.3665747177651092 0.7139362696164402 1.0 1.0 18 P21912 1
Metabolism of steroids 0.3542660483050008 0.3647763047914201 0.7152783941557903 1.0 1.0 40 Q14739,P37268,Q16850,Q53GQ0,Q9Y6B6,Q86X55,P48449 7
Transcriptional regulation of granulopoiesis 0.3972948700728582 0.3580155876727331 0.7203316484160658 1.0 1.0 7 P35659,P16220 2
Cell cycle checkpoints 0.5391877297572136 0.3460247556852722 0.7293241102738057 1.0 1.0 120 Q15008,P25789,P25205,Q96DE5,P33993,O00231,P28072,Q13257,P28074,P55036,P48556,Q9HBM1,P25786,Q9UJX3,P20618,P30307,P28070,Q14566,P49721,Q9P258,P62258,P30153,Q9UJX4,Q12769,Q9UJA3,P62195,Q9UQ84,P49720,P40938,P17980,P35249,P57740,P60900,Q99460,P51665,Q99436,Q14191,Q9UJX6,O14980,O00139,P25788,O43242,P49736,P28066,P33991,Q16537,Q15691,Q16763,O43264,Q9UJX2,Q96EE3,P53350,O00487 53
Piwi interacting rna pirna biogenesis 0.3922448537049753 0.345777846488832 0.7295096753124735 1.0 1.0 10 P52434,Q9Y2W6,P07900,P62875,Q8N2A8,P19388,P19387 7
Extension of telomeres 0.3249461923433048 0.3449777196848251 0.730111120820268 1.0 1.0 30 Q14181,P09884,Q9NX24,P41440,Q8WVB6,Q14191,Q5H9R7,P40938,P28340,P35249 10
Copi independent golgi to er retrograde traffic 0.3170015793279901 0.3446712301189969 0.7303415492689733 1.0 1.0 27 O43237,Q14203,Q9BVA1,P61163,P04350,Q10472,O75935,Q9NP72,Q8TD16,Q15042,P47756,P52907 12
Beta oxidation of hexanoyl coa to butanoyl coa 0.4717368028405285 0.3416637366113014 0.7326039654847425 1.0 1.0 4 Q16836 1
Beta oxidation of lauroyl coa to decanoyl coa coa 0.4717368028405285 0.3416637366113014 0.7326039654847425 1.0 1.0 4 Q16836 1
Infection with mycobacterium tuberculosis 0.3875089620373478 0.3388431575548701 0.7347278874286911 1.0 1.0 12 O14964 1
Response of mtb to phagocytosis 0.3875089620373478 0.3388431575548701 0.7347278874286911 1.0 1.0 12 O14964 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.3799474079174673 0.3371477042835104 0.7360055575574402 1.0 1.0 15 Q9Y6B6 1
Glycerophospholipid biosynthesis 0.329071540713223 0.3293859517245593 0.7418639848095494 1.0 1.0 25 P48651,Q6P1A2,Q8NCC3,Q8IV08,Q99829 5
Transcription coupled nucleotide excision repair tc ner 0.3661131620316779 0.3293666176049635 0.741878596700833 1.0 1.0 47 P52434,P41440,Q92905,P56282,Q9UNP9,Q93009,P61201,Q9NR33,Q99627,P23193,P40938,P19388,P28340,P35249 14
Formation of rna pol ii elongation complex 0.3170585281471622 0.3290834455583321 0.7420926165438746 1.0 1.0 28 P52434,Q8IXH7,Q9H3P2,P23193,P19388,O75909,O00267,P18615,Q7KZ85 9
Metalloprotease dubs 0.4271292893140783 0.3273800739822557 0.7433804355085512 1.0 1.0 5 O95630,Q15018 2
Protein folding 0.3348605700199284 0.3263410877577522 0.7441663047507872 1.0 1.0 35 Q99471,P36404,Q9BVA1,Q15477,O15212,Q15813,Q9UBI6 7
Non integrin membrane ecm interactions 0.4261194299186319 0.3243755166482818 0.7456537533981451 1.0 1.0 5 Q9Y296,P12814 2
Syndecan interactions 0.4261194299186319 0.3243755166482818 0.7456537533981451 1.0 1.0 5 Q9Y296,P12814 2
Polb dependent long patch base excision repair 0.4259371849556423 0.3238346192312651 0.7460632449335165 1.0 1.0 5 Q9NX46 1
Rna polymerase ii transcribes snrna genes 0.3569174503148207 0.3218399609249638 0.7475739391656617 1.0 1.0 20 Q9BXP5,Q9H814,Q96SY0,P19388,O75909,O00267,Q9NQG5 7
Phospholipid metabolism 0.3417053440301411 0.321052603821205 0.7481705271112287 1.0 1.0 38 P48651,Q9NPH0,Q8TBX8,Q9Y217,Q6P1A2,Q13614,Q8N9F7,Q8IV08,Q8NCC3,Q99829,O14735,O15228,Q8NEB9 13
Hiv transcription elongation 0.3500530878282923 0.3131075950993021 0.7541989189676586 1.0 1.0 21 P52434,P19447,Q8IXH7,Q9Y5B9,P32780,Q9H3P2,P23193,P19388,P19387,O00267,P18615 11
Formation of tubulin folding intermediates by cct tric 0.3786275179242124 0.3126427856240579 0.7545520682232103 1.0 1.0 13 P50990,P40227,P68371,Q99832,P17987,Q9BVA1,P48643,P04350,Q9BUF5,P50991,Q13885,P78371 12
Synthesis of pips at the late endosome membrane 0.4609904226274732 0.3117269865852091 0.7552480168635256 1.0 1.0 4 Q8NEB9 1
Nucleotide excision repair 0.3805569391637765 0.3116550036359525 0.7553027277266351 1.0 1.0 54 P52434,P41440,Q92905,P56282,Q9UNP9,Q93009,P61201,Q9NR33,Q99627,P23193,P40938,P19388,Q86WJ1,O75925,P28340,P35249 16
Coenzyme a biosynthesis 0.7047619047619056 0.3102141683709446 0.7563980968455919 1.0 1.0 2 Q13057 1
Metabolism of vitamins and cofactors 0.3567579575825973 0.3048515277448489 0.760479234735056 1.0 1.0 45 Q9H2D1,P41440,P34896,P78417,P11166,P01130,Q99707,Q9NRN7,P35270,O75874 10
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3783691572842016 0.3004042222711663 0.763868843426946 1.0 1.0 11 P50990,P40227,Q99832,P17987,P48643,P67870,P50991,P19784,Q9UBI6,P78371 10
Signalling to ras 0.5863091556945155 0.2965280508536199 0.7668268482008422 1.0 1.0 3 P62993 1
Bbsome mediated cargo targeting to cilium 0.3777247956403257 0.296222784062009 0.7670599500713806 1.0 1.0 6 P50990,P17987,P48643,P50991,P78371 5
Folding of actin by cct tric 0.3779822767552779 0.2939943732148625 0.7687622030049188 1.0 1.0 8 P50990,P40227,Q99832,P17987,P48643,P50991,P78371 7
Pexophagy 0.6952380952380925 0.2891941841313097 0.7724327821939152 1.0 1.0 2 P50542 1
Mitotic prometaphase 0.4410454344376628 0.2864805305975164 0.7745101032051256 1.0 1.0 81 O75935,O95684,Q7Z5K2,Q9HBM1,Q12769,P30153,Q9BVA1,Q68CZ6,Q9H6D7,Q9NTJ3,O43805,O14980,O00139,Q16537,Q15691,Q8WVM7,O43264,Q96EE3,P53350 19
Pi3k akt signaling in cancer 0.3716474485727426 0.2739478407252671 0.7841247057599854 1.0 1.0 8 P16220,P62993 2
Signaling by scf kit 0.3707157377140465 0.2725282914506935 0.7852158407811007 1.0 1.0 7 Q06124,P62993 2
Class b 2 secretin family receptors 0.6850340136054489 0.2676250949929735 0.7889879123538388 1.0 1.0 2 Q9UBI6 1
Regulation of tp53 expression and degradation 0.3676124604589772 0.2631985278733126 0.792397565401979 1.0 1.0 7 P30153 1
Deadenylation dependent mrna decay 0.3258443860721154 0.2598868160693946 0.7949510812003111 1.0 1.0 36 Q9Y4Z0,Q15477,Q9HBH5,O95628,Q9Y3B2,Q9UIV1 6
Tp53 regulates transcription of dna repair genes 0.3095243679783204 0.2592931075528162 0.79540909698395 1.0 1.0 26 P52434,P19447,Q8IXH7,Q9NYV4,Q9H3P2,P23193,P19388,O75909,P19387,O00267,P18615,P43246 12
G alpha i signalling events 0.3321569304405922 0.2530726199875497 0.8002120964015855 1.0 1.0 22 P04083,P30153,Q9NRV9,O43865,P16220 5
Gap filling dna repair synthesis and ligation in gg ner 0.3431574735910631 0.2422358929446901 0.8085973845219887 1.0 1.0 19 P41440,P56282,P40938,P28340,P35249 5
Organelle biogenesis and maintenance 0.4525388982941607 0.2386832198362345 0.8113512293683756 1.0 1.0 90 O43924,A6NIH7,P30153,Q96KP1,Q13505,O75935,O43805,P48735,P53350,O95684,Q9H6D7 11
Kinesins 0.3510231614637386 0.235301021830863 0.8139751020794641 1.0 1.0 16 Q9BVA1,Q9NQT8,Q14807,O00139,P52732,O95239 6
Intraflagellar transport 0.3590811459614191 0.23474946538356 0.8144031924796158 1.0 1.0 9 Q9BW83,Q9BVA1,Q92973,P04350,Q9BUF5 5
Urea cycle 0.6646258503401326 0.2275299314932654 0.8200116975280338 1.0 1.0 2 P78540 1
Rna polymerase iii transcription 0.355312411524502 0.2261158759589975 0.8211112971074173 1.0 1.0 12 P52434,P05455,O14802,P19388 4
Signaling by insulin receptor 0.3500948578059398 0.2235108704014168 0.823137923755584 1.0 1.0 15 Q9Y487,P62993,Q8NEB9 3
Glutathione synthesis and recycling 0.3511156460141706 0.21987793840856 0.8259662184647607 1.0 1.0 6 P48507,Q96KP4 2
Mrna decay by 3 to 5 exoribonuclease 0.348831393715091 0.2190639160180637 0.8266002589121244 1.0 1.0 15 Q9Y3B2,Q15477 2
Cdc6 association with the orc origin complex 0.4232926321787178 0.2177518545662044 0.8276224588479804 1.0 1.0 4 Q9UJA3,O43913 2
Protein methylation 0.3512776831345717 0.216542976253228 0.8285645295094173 1.0 1.0 7 O60678,P55072,P13639,P15880,O60870,P11142 6
Gaba synthesis release reuptake and degradation 0.6571428571428537 0.2138667487849049 0.8306509709151437 1.0 1.0 2 P11142 1
Fatty acid metabolism 0.3571950277622654 0.2125699364772992 0.8316624227225362 1.0 1.0 52 P11310,Q14914,Q8N8N7,O43772 4
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3845917810172092 0.2123875768028402 0.8318046769804557 1.0 1.0 5 Q9UBI6 1
Initiation of nuclear envelope ne reformation 0.341851802501679 0.2112236465391796 0.8327127597228412 1.0 1.0 17 Q14739,P30153 2
Resolution of abasic sites ap sites 0.3064769005400124 0.2100445052348766 0.8336329375846077 1.0 1.0 25 P41440,P56282,P40938,P28340,P35249 5
Uptake and function of anthrax toxins 0.6530612244897902 0.2066519738934971 0.8362816669632955 1.0 1.0 2 Q8WUM4 1
Downstream signal transduction 0.3451865009608404 0.2043590027965087 0.8380729651188552 1.0 1.0 6 P62993 1
Signaling by pdgf 0.3451865009608404 0.2043590027965087 0.8380729651188552 1.0 1.0 6 P62993 1
Uptake and function of diphtheria toxin 0.413886997957794 0.1971871093072014 0.8436811178579307 1.0 1.0 4 P13639,P08238,P07900 3
Senescence associated secretory phenotype sasp 0.3374670675696486 0.1952081049956066 0.8452300342510253 1.0 1.0 17 P11802,Q96DE5,Q16763,Q9UJX4,Q9UJX2,Q00534,Q9UJX3 7
Gpcr ligand binding 0.3444462669085084 0.1926667037404401 0.847220001407136 1.0 1.0 9 Q9NRV9,Q9BYT8,P04083 3
Crmps in sema3a signaling 0.3753117703145096 0.1906940355271204 0.8487653119031777 1.0 1.0 5 Q9BPU6 1
Ret signaling 0.4107548947345602 0.1906069794757066 0.8488335216192682 1.0 1.0 4 P62993 1
Synthesis of pg 0.5327522798894077 0.1853128018761969 0.8529836974868628 1.0 1.0 3 Q8IV08 1
Signaling by notch1 0.3402212716215478 0.1838680357584652 0.8541169810240463 1.0 1.0 8 P63208,Q13616,Q96J02 3
Signaling by kit in disease 0.3717051204127263 0.1826125163284239 0.8551020628787238 1.0 1.0 5 P62993 1
Processive synthesis on the lagging strand 0.3402459528776093 0.1814278172073647 0.856031786197609 1.0 1.0 13 P09884,P12004,Q14181,P18858,P28340 5
Formyl peptide receptors bind formyl peptides and many other ligands 0.5304735815348827 0.181290449897581 0.856139601705957 1.0 1.0 3 Q9NRV9 1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3407567830612483 0.1804465107798827 0.8568020432189081 1.0 1.0 11 O43765 1
Rhov gtpase cycle 0.3370368027803073 0.17911393508347 0.8578482403343111 1.0 1.0 15 Q9NNW5,Q13177,Q00610,Q13153,Q13813,Q03001,O43396,P46940,P06753,P67936 10
Intrinsic pathway for apoptosis 0.3344315682551957 0.1765447934906694 0.8598659611637851 1.0 1.0 16 Q9NR28 1
Synthesis of bile acids and bile salts 0.4032915567962907 0.1754742334123997 0.860707015405695 1.0 1.0 4 Q96SU4 1
Bile acid and bile salt metabolism 0.4032915567962907 0.1754742334123997 0.860707015405695 1.0 1.0 4 Q96SU4 1
Host interactions of hiv factors 0.438884912291746 0.1720936860711061 0.86336387649641 1.0 1.0 90 Q15008,P25789,P53680,Q10567,O00231,P28072,P63208,P28074,P55036,P48556,P25786,P20618,P28070,Q9NRG9,P49721,Q12769,P62195,P49720,P17980,P57740,P60900,Q99460,Q9BXS5,P51665,Q99436,O14980,P25788,O94973,O43242,P12270,P28066,Q5SRE5,Q96EE3,O00487 34
Condensation of prometaphase chromosomes 0.3362567054437465 0.1707568581411563 0.8644149529725256 1.0 1.0 9 Q9NTJ3 1
Trafficking of glur2 containing ampa receptors 0.3312358747303047 0.1701329929376797 0.8649055471287432 1.0 1.0 6 P53680 1
Anti inflammatory response favouring leishmania parasite infection 0.3340219250410786 0.1693692521909046 0.8655062072766155 1.0 1.0 15 P16220,Q9UBI6,O43865 3
Tp53 regulates transcription of death receptors and ligands 0.5221503412917305 0.1671030245769938 0.867288986209763 1.0 1.0 3 Q13625 1
Tp53 regulates transcription of cell death genes 0.5221503412917305 0.1671030245769938 0.867288986209763 1.0 1.0 3 Q13625 1
Ion transport by p type atpases 0.334200740569925 0.1654473206536958 0.8685919103400181 1.0 1.0 9 Q9HD20,Q9NQ11 2
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3332505481744282 0.1607917228107679 0.8722574446498745 1.0 1.0 10 P07196 1
Hsf1 dependent transactivation 0.3332944785006072 0.1595461217406925 0.8732386237601084 1.0 1.0 12 Q02790,P07900,P0DMV9,Q13555,Q92598,P11142 6
Signaling by egfr in cancer 0.3946891559038608 0.158996389224442 0.8736717186262963 1.0 1.0 4 P62993 1
Signaling by erbb2 ecd mutants 0.3946891559038608 0.158996389224442 0.8736717186262963 1.0 1.0 4 P62993 1
Signaling by erbb2 in cancer 0.3946891559038608 0.158996389224442 0.8736717186262963 1.0 1.0 4 P62993 1
Constitutive signaling by ligand responsive egfr cancer variants 0.3946891559038608 0.158996389224442 0.8736717186262963 1.0 1.0 4 P62993 1
Constitutive signaling by egfrviii 0.3946891559038608 0.158996389224442 0.8736717186262963 1.0 1.0 4 P62993 1
Synthesis of pa 0.3280059307537618 0.1576745196967314 0.8747132796391917 1.0 1.0 7 O15228,Q9NPH0,Q8N2A8 3
Integration of energy metabolism 0.3095164392392478 0.154340739754818 0.877341076456855 1.0 1.0 22 P11166,O43865 2
Mitotic metaphase and anaphase 0.5147712233032371 0.1525905016569771 0.8787212158573832 1.0 1.0 127 Q15008,P25789,Q96DE5,Q13200,P61289,O00231,O43237,P28072,Q13257,P28074,P55036,P48556,Q9HBM1,Q7Z5K2,P42166,Q9UJX3,P25786,P20618,P28070,P49721,Q9P258,Q12769,P30153,Q9UJX4,Q9BVA1,Q9UQN3,P62195,P49720,P17980,P57740,P60900,Q99460,P51665,Q8WUX9,Q99436,Q9Y3E7,Q9UJX6,Q9UN37,O14980,O00139,P25788,O43242,P63151,Q14739,P28066,Q5SRE5,Q16537,P25787,Q15691,P50402,Q16763,Q92973,Q8WVM7,O43264,Q9UJX2,Q96EE3,P53350,O00487 58
Hiv transcription initiation 0.3277313344646917 0.1442267272471784 0.885321436294715 1.0 1.0 12 P52434,P19447,Q92804,P32780,P62875,P19388,P19387 7
Interleukin 17 signaling 0.3271994589838383 0.1432156036030463 0.8861199069596999 1.0 1.0 13 P16220,P30153,Q13616 3
Rho gtpases activate formins 0.3366227839501719 0.1355873085654161 0.8921475390901819 1.0 1.0 50 P57740,Q16537,Q9P258,Q15691,Q12769,P30153,O43237,Q9NSV4,Q13257,Q9BVA1,O43264,Q96EE3,P53350,Q9HBM1,O14980,O00139 16
Cytosolic sensors of pathogen associated dna 0.3191801024397467 0.1331212959633825 0.8940974532954695 1.0 1.0 17 P52434,P19474,P19388,Q9H2U1 4
Signaling by met 0.3219749253410878 0.1324162253584011 0.8946550817016554 1.0 1.0 15 Q06124,O14964,P62993 3
Transcriptional activation of mitochondrial biogenesis 0.3231526493909488 0.1320822143076881 0.8949192635784273 1.0 1.0 13 Q96RR1,P48735,P16220,Q86X55,P06576 5
Toll like receptor 9 tlr9 cascade 0.3138302214525549 0.1310107694289451 0.8957667880646216 1.0 1.0 19 Q8NEB9,P16220,P30153,Q13616 4
Cell cell communication 0.2944374951302555 0.1297618298272805 0.8967548629022861 1.0 1.0 24 P19022,Q06124,P62993,Q13813,P12814,O43707,P46940,O14936,Q8NI35 9
Microrna mirna biogenesis 0.3216629107852435 0.1294761471388467 0.896980897893759 1.0 1.0 11 P52434,P62875,P30876,Q9HAV4,P19388,Q9UPY3,P19387 7
Base excision repair 0.2802411319652629 0.128392317648178 0.8978385104696649 1.0 1.0 28 P41440,P56282,P40938,P28340,P35249 5
Signaling by notch1 pest domain mutants in cancer 0.3138628436271733 0.1265319651929874 0.8993108478145395 1.0 1.0 7 Q13616 1
Cell surface interactions at the vascular wall 0.3166740054967363 0.1203853085431835 0.9041779288438708 1.0 1.0 16 P14174,Q06124,P62993 3
Regulation of kit signaling 0.4856325504553114 0.1141887090463085 0.9090882022391712 1.0 1.0 3 P62993 1
Cd28 dependent vav1 pathway 0.3029815754118689 0.1110819647692048 0.9115513502532088 1.0 1.0 6 P62993 1
Signal regulatory protein family interactions 0.4786790517382911 0.1058043810173039 0.91573756075486 1.0 1.0 3 P62993 1
Mrna capping 0.3121870048160622 0.1036364700092602 0.9174578446021447 1.0 1.0 14 P52434,P19447,O43148,P32780,P62875,P19388,P19387,O00267 8
Rna polymerase iii transcription initiation from type 1 promoter 0.3101085693412427 0.1021685972459685 0.918622853058592 1.0 1.0 11 P52434,O14802,P19388 3
Type i hemidesmosome assembly 0.5741496598639366 0.1000326113901136 0.9203184351393978 1.0 1.0 2 Q03001 1
Assembly of collagen fibrils and other multimeric structures 0.5741496598639366 0.1000326113901136 0.9203184351393978 1.0 1.0 2 Q03001 1
Oxidative stress induced senescence 0.3084014262438719 0.0959645072807797 0.9235487615102078 1.0 1.0 12 Q00534,Q9HC52,Q9HCE1 3
Adora2b mediated anti inflammatory cytokines production 0.3017396953935455 0.0921593786412575 0.9265714117929504 1.0 1.0 9 P16220 1
Mapk1 erk2 activation 0.4648296101591251 0.0906524561414411 0.9277687495114224 1.0 1.0 3 Q06124 1
Scavenging by class f receptors 0.3427501701838 0.0815099900305008 0.9350363804207013 1.0 1.0 4 P27797,Q92598,P07900 3
Sensory perception 0.2861565773119794 0.0802669070362245 0.9360249776235364 1.0 1.0 23 Q14651,Q00013,P01130,Q12792,Q13813,P15311,P29375,P47756,O14936,P52907,P49354 11
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.2976178058193602 0.079692163615306 0.936482092160474 1.0 1.0 10 P53680,Q10567,O94973 3
Iron uptake and transport 0.3007353443630557 0.0787194605995783 0.9372557661928504 1.0 1.0 17 P21399,P30519,P63208,Q13616 4
Downstream signaling of activated fgfr1 0.4485193424031911 0.0753411614582384 0.939943272419786 1.0 1.0 3 P62993 1
Downstream signaling of activated fgfr2 0.4485193424031911 0.0753411614582384 0.939943272419786 1.0 1.0 3 P62993 1
Downstream signaling of activated fgfr3 0.4485193424031911 0.0753411614582384 0.939943272419786 1.0 1.0 3 P62993 1
Downstream signaling of activated fgfr4 0.4485193424031911 0.0753411614582384 0.939943272419786 1.0 1.0 3 P62993 1
Oas antiviral response 0.448111602585919 0.074992050116498 0.9402210371705276 1.0 1.0 3 Q6L8Q7,P21333 2
Activation of ampk downstream of nmdars 0.2836082325569342 0.0720670877133091 0.9425485182966192 1.0 1.0 7 P54619,Q9BVA1,P04350,Q9BUF5 4
Signalling to erks 0.2868207756244725 0.0709332423625783 0.943450886421246 1.0 1.0 8 P62993 1
Molybdenum cofactor biosynthesis 0.4382443007825887 0.0670229138429146 0.94656346160365 1.0 1.0 3 Q9NZB8,Q9NQX3 2
Cell junction organization 0.2970899844753543 0.0666362985686358 0.9468712478751122 1.0 1.0 15 P19022,P12814 2
Rap1 signalling 0.4310990132698259 0.061808758916973 0.9507151282193989 1.0 1.0 3 P63104,P31946 2
Dna damage reversal 0.3223281143635175 0.060921363306623 0.9514218355860063 1.0 1.0 4 Q8N3C0,Q6P6C2,Q9H1I8 3
Wnt ligand biogenesis and trafficking 0.2969373904775968 0.0604593230548631 0.9517898120545404 1.0 1.0 5 Q96QK1 1
Pyruvate metabolism and citric acid tca cycle 0.2751519261131052 0.0604056733821348 0.9518325402053582 1.0 1.0 32 P48735,P21912 2
Signal amplification 0.2755688775401416 0.0603577403700554 0.951870715559448 1.0 1.0 7 Q14344 1
Nod1 2 signaling pathway 0.3192648059904768 0.0582718592869907 0.9535320824502976 1.0 1.0 4 Q13685,Q15750,Q96J02 3
Signaling by gpcr 0.2904971267085338 0.0521605372792289 0.9584007767943368 1.0 1.0 39 Q9BYT8,P30153,Q9NRV9,P62993,Q14344,O43865,P04083,O75116,P16220 9
Notch hlh transcription pathway 0.3114363512593652 0.0519908014320417 0.95853602289639 1.0 1.0 4 Q06330,Q92769,Q13573 3
Abc transporters in lipid homeostasis 0.5027210884353658 0.0514885662082009 0.9589362126116288 1.0 1.0 2 P40855 1
Bmal1 clock npas2 activates circadian gene expression 0.4140063471742783 0.0511032668479304 0.9592432328280484 1.0 1.0 3 Q86X55 1
Telomere maintenance 0.2926125938072322 0.0507520586488038 0.9595230932641284 1.0 1.0 40 Q14181,P09884,Q9NX24,P12004,P52434,P18858,P41440,Q8WVB6,Q14191,Q5H9R7,P40938,P19388,P19387,P28340,P35249 15
Signaling by mras complex mutants 0.4969387755101971 0.0491100117373333 0.9608316248235652 1.0 1.0 2 P31946 1
Erbb2 regulates cell motility 0.4942176870748177 0.0480560279687792 0.961671590286466 1.0 1.0 2 O60610 1
Fanconi anemia pathway 0.2839632277834465 0.0477469024180484 0.9619179539806124 1.0 1.0 5 P15927,Q9NPD8,Q16658,P27694 4
Mitochondrial protein import 0.2791149008859712 0.0461463797468579 0.9631935796670426 1.0 1.0 35 Q9NS69,O60830,Q13505,Q99595,Q15388,Q5JRX3,Q9Y512 7
Cargo recognition for clathrin mediated endocytosis 0.2740562870726414 0.0457542463137969 0.9635061267419892 1.0 1.0 33 P53680,Q9UHD9,Q92905,O14656,P01130,P61201,Q99627,P62993,O14964 9
Signaling by ntrk2 trkb 0.2815028624456031 0.0455893697089869 0.9636375421071788 1.0 1.0 5 P62993 1
Negative regulators of ddx58 ifih1 signaling 0.2554495912806555 0.0430951900189565 0.9656256535478912 1.0 1.0 6 Q14258,Q15366,P61086,Q13526,Q96J02 5
Aggrephagy 0.2853018253493453 0.0424884456727111 0.9661093224512596 1.0 1.0 14 Q13409,Q9BVA1,O43237,Q9BUF5,P04350,P08670,Q13885 7
Sema4d in semaphorin signaling 0.2575766913647708 0.0381657164761673 0.969555555258612 1.0 1.0 7 O75116,P35579 2
Epha mediated growth cone collapse 0.2605487382710133 0.0346109701852296 0.9723899537991592 1.0 1.0 8 P07947,O75116,P35579 3
Signaling by nuclear receptors 0.3151809014088355 0.0339468085360974 0.9729195668648608 1.0 1.0 51 O14980,Q9HBH5,Q8WVM7,Q8NB78,P19388,P16220,Q86X55,Q15120 8
Synthesis of diphthamide eef2 0.4299319727891099 0.0327619851959444 0.9738643933466212 1.0 1.0 2 Q9H2P9 1
E2f enabled inhibition of pre replication complex formation 0.2631108261237466 0.0318305880727451 0.9746071532354366 1.0 1.0 5 Q9UJA3,O43913 2
Notch4 intracellular domain regulates transcription 0.3680272108843538 0.0284219008675373 0.9773256568894207 1.0 1.0 2 Q13573 1
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.3680272108843538 0.0284219008675373 0.9773256568894207 1.0 1.0 2 Q13573 1
Regulation of beta cell development 0.3680272108843538 0.0284219008675373 0.9773256568894207 1.0 1.0 2 Q13573 1
Runx3 regulates notch signaling 0.3680272108843538 0.0284219008675373 0.9773256568894207 1.0 1.0 2 Q13573 1
Fructose metabolism 0.3612244897959218 0.0282335237827973 0.9774758997627324 1.0 1.0 2 P15121 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.3190476190476211 0.0276278219385747 0.9779589914332124 1.0 1.0 2 P54619 1
Cd163 mediating an anti inflammatory response 0.3190476190476232 0.0276278219385747 0.9779589914332124 1.0 1.0 2 P35579 1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.3170068027210905 0.0276144205771394 0.977969680094487 1.0 1.0 2 P49327 1
P75ntr negatively regulates cell cycle via sc1 0.3112244897959247 0.0275812677428189 0.9779961221575396 1.0 1.0 2 Q92769 1
Apoptosis 0.383702556091494 0.0254140184016187 0.9797247296522332 1.0 1.0 81 P28070,P49721,Q13625,P60900,O00231,P28072,P28074,P49720,Q9NR28,P20618,P25786,P08670,P25788 13
Adrenaline noradrenaline inhibits insulin secretion 0.3255993142422573 0.0249229011664843 0.9801164604169108 1.0 1.0 3 Q9UBI6 1
Lipophagy 0.2675652626152804 0.0215554235318907 0.9828025921292628 1.0 1.0 3 P54619 1
Toll like receptor tlr1 tlr2 cascade 0.2751602387123354 0.0188426498323405 0.9849666302076884 1.0 1.0 16 P16220,P30153,Q13616 3
Cd28 co stimulation 0.2507522597040256 0.0173106397879266 0.9861887975524972 1.0 1.0 9 P62993,P07947 2
Activation of rac1 0.207694926796051 0.0103238705790125 0.9917628893792432 1.0 1.0 5 O94813,Q16512,Q13177,Q13153 4
Ephrin signaling 0.2076949267960502 0.0103238705790125 0.9917628893792432 1.0 1.0 5 O00560,Q16512,Q13177,Q13153 4
Regulation of tp53 activity through acetylation 0.248379392698736 0.0020343814964515 0.9983767995328572 1.0 1.0 11 Q14839,O94776,Q9HAF1,Q86YP4,Q13547,Q8TBX8,O95983,Q13526,Q8WXI9,Q92769 10
Signaling by moderate kinase activity braf mutants 0.2473558512453073 0.0009856756288869 0.999213544761099 1.0 1.0 11 P41240,P31946,Q13555,P36507,P30086,P28482,P46940,P35232,Q9Y490,P18206 10
Programmed cell death 0.4083510078301049 4.238188440633643e-05 0.9999661841487846 1.0 1.0 95 P28070,P49721,Q13625,P60900,P41440,Q8WUX9,O00231,Q9UNE7,P28072,Q9UQN3,P28074,P49720,Q9NR28,P20618,P25786,P08670,P25788,O15294 18