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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Glycosphingolipid metabolism 0.8266400140301147 3.381282161148515 0.0007214841440388 0.6322448557018929 0.4065756481388693 17 O43681,P10619,P16278,P17900,Q9NZD2,P07602,Q13510,P04062,P06865,P06280 10
Glycosaminoglycan metabolism 0.7512791883743124 2.9846510236142265 0.0028390201549772 0.9805610818784598 0.4763534957291425 16 Q7LGA3,P16278,O43505,P54802,P06865,Q8NCH0,Q11206 7
Diseases associated with glycosaminoglycan metabolism 0.9563676835840084 2.4798609337967816 0.0131433632745172 0.9999999891323492 0.7882077841804974 4 Q8NCH0 1
Chondroitin sulfate dermatan sulfate metabolism 0.9563676835840084 2.4798609337967816 0.0131433632745172 0.9999999891323492 0.7882077841804974 4 Q8NCH0 1
Gpcr ligand binding 0.7324813892286676 2.4513928705694292 0.0142304539382276 0.9999999976411496 0.7882077841804974 11 P07602,P42892,Q9NRV9 3
Mitochondrial calcium ion transport 0.6619257898493454 2.4120142786230914 0.0158646602125152 0.999999999763413 0.7882077841804974 18 P21796,Q9H4I9,Q10713,P45880 4
Class a 1 rhodopsin like receptors 0.7734015612696011 2.4050201392230877 0.0161715745595611 0.9999999998464528 0.7882077841804974 8 P07602,P42892,Q9NRV9 3
Peptide ligand binding receptors 0.7734015612696011 2.4050201392230877 0.0161715745595611 0.9999999998464528 0.7882077841804974 8 P07602,P42892,Q9NRV9 3
Pink1 prkn mediated mitophagy 0.7673178490630157 2.3752613052844787 0.0175365305991985 0.9999999999775846 0.7882077841804974 8 P21796,Q9NS69 2
Sphingolipid metabolism 0.6857772677150915 2.333735096777788 0.0196095971378187 0.9999999999988004 0.7882077841804974 28 Q16739,O43681,P10619,P51648,P16278,P17900,Q9NZD2,P07602,Q13510,P04062,Q06136,O15269,P06865,Q96G23,P06280 15
Metabolism of porphyrins 0.7268843222186667 2.3321618056535947 0.019692180631752 0.9999999999989324 0.7882077841804974 10 P30519,P09601 2
Keratan sulfate keratin metabolism 0.7979091150364919 2.2735995410549745 0.0229900750883522 0.99999999999999 0.7882077841804974 7 P06865,Q11206,P16278 3
Ras processing 0.8637697286031022 2.2150402720955795 0.0267573004348602 1.0 0.7882077841804974 5 O43924 1
Heparan sulfate heparin hs gag metabolism 0.8231734840053515 2.158714558244187 0.0308723186351831 1.0 0.7882077841804974 6 P54802,Q7LGA3,P16278 3
Nucleotide salvage 0.7135419807099694 2.1076513036017444 0.0350611623816865 1.0 0.7882077841804974 8 P00813,P55263 2
Class i peroxisomal membrane protein import 0.6489878866048737 2.086200243327103 0.0369604882200038 1.0 0.7882077841804974 12 O75381,P51648,Q5T8D3,P40855,Q9Y5Y5,P28288 6
Heme degradation 0.8602770842531927 2.082593327554744 0.0372883079358077 1.0 0.7882077841804974 4 P30519 1
Interleukin 4 and interleukin 13 signaling 0.6469457653607087 2.074562793640977 0.0380270733895502 1.0 0.7882077841804974 12 P09601 1
Keratan sulfate degradation 0.8564070179280493 2.066251420514414 0.0388047458430285 1.0 0.7909320255652575 4 P06865 1
Mucopolysaccharidoses 0.8441531459545394 2.014339270083185 0.0439739256618403 1.0 0.819991250139303 4 P16278,P54802 2
Mitophagy 0.6353506256985103 2.0082140404434883 0.0446205516411131 1.0 0.819991250139303 12 P21796,Q9NS69 2
Amino acid transport across the plasma membrane 0.8355867104633852 1.97789848882078 0.0479401594786375 1.0 0.819991250139303 4 P30825 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5986329233035987 1.971160440687516 0.0487055271962026 1.0 0.819991250139303 20 O76024,Q02818,P05067,Q9BTY2,O43852,Q07065,O43493 7
Diseases of carbohydrate metabolism 0.654115101891336 1.944662890861224 0.0518155646155589 1.0 0.819991250139303 10 P08236,P16278,P10253,P54802,P46976 5
Iron uptake and transport 0.5829919933674632 1.9442269434349408 0.0518680900388539 1.0 0.819991250139303 17 Q93050,P30519,Q15904,P09601 4
Purine salvage 0.7974290218644275 1.927660105431524 0.0538974174075388 1.0 0.819991250139303 5 P00813 1
Stimuli sensing channels 0.6626519026587097 1.9156470747307304 0.0554100332998723 1.0 0.819991250139303 9 Q96PU5,Q9C0H2,P51790 3
Transport of inorganic cations anions and amino acids oligopeptides 0.618700529432351 1.9121421547641873 0.0558579631686977 1.0 0.819991250139303 12 Q70HW3,Q9UBX3,P08195,P30825 4
Cyclin d associated events in g1 0.631797196612824 1.901367577173252 0.0572538832713525 1.0 0.819991250139303 11 P30154,P63208,P63151 3
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.658205679916114 1.892054448276006 0.0584837266362257 1.0 0.819991250139303 9 P06493,Q9Y3B8,P62258,P63104,Q04917 5
O linked glycosylation 0.7632399611902965 1.8910313028545145 0.0586201657473277 1.0 0.819991250139303 6 Q10472,Q11206 2
Metabolism of cofactors 0.7627640266472753 1.8888769671822052 0.058908316419554 1.0 0.819991250139303 6 O75208,O75874 2
O linked glycosylation of mucins 0.7870440370317513 1.8819434546505664 0.0598436935121728 1.0 0.819991250139303 5 Q10472,Q11206 2
Purinergic signaling in leishmaniasis infection 0.8002271253599998 1.826225332855388 0.0678163269557181 1.0 0.819991250139303 4 P09601 1
The nlrp3 inflammasome 0.80022712536 1.826225332855388 0.0678163269557181 1.0 0.819991250139303 4 P09601 1
Inflammasomes 0.8002271253599998 1.826225332855388 0.0678163269557181 1.0 0.819991250139303 4 P09601 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5507227535589703 1.786388955455949 0.0740363026360431 1.0 0.819991250139303 15 Q9UHV9,Q9BUF5,Q99832,Q99471,P61758,P78371,P48643,Q13885,O15212 9
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5952870387141117 1.7754987303894163 0.0758155750014983 1.0 0.819991250139303 12 O43681,P51648,P46379,P05067,P09601 5
Diseases of glycosylation 0.5507242200946725 1.7611095554589231 0.0782198620350242 1.0 0.819991250139303 16 P10619,P16278,O43505,P06865,Q8NCH0,Q86SQ9 6
Synthesis of pa 0.6458413064201822 1.7592577453479112 0.0785337401004073 1.0 0.819991250139303 8 Q8N2A8,Q9HCL2,Q9NPH0 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.6322510297944175 1.7532354165205442 0.0795616060955908 1.0 0.819991250139303 9 Q14168,Q12959,P07196,Q92796 4
Hyaluronan uptake and degradation 0.7763143480460419 1.7225778119417148 0.0849649002881167 1.0 0.8342929683444268 4 P06865 1
Hyaluronan metabolism 0.7763143480460419 1.7225778119417148 0.0849649002881167 1.0 0.8342929683444268 4 P06865 1
Abc transporters in lipid homeostasis 0.9047235534415068 1.6852108600587712 0.0919478965202129 1.0 0.8668342150964856 3 P40855 1
Long term potentiation 0.7167224827767872 1.6784858143148116 0.0932522974870218 1.0 0.8668342150964856 6 Q14168,P07196,Q92796 3
Sialic acid metabolism 0.7157851677707698 1.6741639596313858 0.0940983804389277 1.0 0.8668342150964856 6 P10619,Q11206 2
Regulation of tp53 expression and degradation 0.6169033972972398 1.6703001472571055 0.0948599940699992 1.0 0.8668342150964856 9 P30154,Q93009,Q9UER7,P30153 4
Pregnenolone biosynthesis 0.7375555119809605 1.661616867097622 0.096589619217128 1.0 0.8668342150964856 5 O95772 1
Budding and maturation of hiv virion 0.5759643195305942 1.6614366929505588 0.0966257735534947 1.0 0.8668342150964856 12 Q8WUX9,Q96PU5,Q9H9H4,Q9NP79,Q99816 5
Metabolism of steroid hormones 0.6689580024362183 1.6561131278708072 0.0976989112893784 1.0 0.8668342150964856 7 O95772 1
Assembly and cell surface presentation of nmda receptors 0.6133027290879672 1.6507561203005907 0.0987883833409464 1.0 0.8668342150964856 9 Q92796,O14936,Q14168,Q12959,P07196 5
G2 m dna replication checkpoint 0.7593028589559557 1.6483672898518629 0.0992773240928106 1.0 0.8668342150964856 4 O95067,Q99640 2
Cyclin a b1 b2 associated events during g2 m transition 0.5703642914597391 1.628174146612097 0.1034879650679563 1.0 0.8668342150964856 12 Q99640,P30154,O95067,P30153,P63151 5
Pre notch processing in golgi 0.7053754149097924 1.626070028282062 0.1039347590599395 1.0 0.8668342150964856 6 Q15363,Q11206 2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.6075081482829422 1.6192369505221518 0.1053962905426937 1.0 0.8668342150964856 9 Q96J02,P05067,P09601 3
Methionine salvage pathway 0.8845568634861154 1.6066894869552144 0.1081225009629276 1.0 0.8668342150964856 3 Q13126 1
N glycan antennae elongation in the medial trans golgi 0.8843357265907799 1.6058267993964428 0.1083119705781445 1.0 0.8668342150964856 3 P04066 1
Synthesis of pips at the golgi membrane 0.6038487843750817 1.5992905728907516 0.1097560532339037 1.0 0.8668342150964856 9 Q8NEB9,Q10713 2
Ras activation upon ca2 influx through nmda receptor 0.7227673980689293 1.5950616964014854 0.1106984398698189 1.0 0.8668342150964856 5 Q14168,P07196,Q92796 3
Negative regulation of nmda receptor mediated neuronal transmission 0.7227673980689293 1.5950616964014854 0.1106984398698189 1.0 0.8668342150964856 5 Q14168,P07196,Q92796 3
Unblocking of nmda receptors glutamate binding and activation 0.7227673980689293 1.5950616964014854 0.1106984398698189 1.0 0.8668342150964856 5 Q14168,P07196,Q92796 3
Retrograde transport at the trans golgi network 0.5381197131807569 1.5802210172907631 0.1140562602310049 1.0 0.8818352364601993 20 Q9H9E3,Q8N2H4,O60499 3
Endosomal sorting complex required for transport escrt 0.5434464156956735 1.548871611660159 0.1214125864430035 1.0 0.9128417115088509 13 Q8WUX9,Q9H9H4,Q9BRG1,Q9NP79,Q99816,Q9UK41,Q92783 7
Transport of bile salts and organic acids metal ions and amine compounds 0.7107625243356452 1.5408236351201936 0.1233597154778829 1.0 0.9128417115088509 5 Q8TAD4 1
Hs gag degradation 0.8581829692940782 1.503586905012105 0.1326877649574029 1.0 0.9197957956473886 3 P16278,P54802 2
Heme biosynthesis 0.6776570862855353 1.4972172972524984 0.134336726004983 1.0 0.9197957956473886 6 P22830 1
Glycogen storage diseases 0.7245435469503617 1.4956882263616222 0.1347349198374572 1.0 0.9197957956473886 4 P46976,P10253 2
Vitamin b5 pantothenate metabolism 0.7242856643124173 1.4945510202336392 0.1350316571086005 1.0 0.9197957956473886 4 Q13057,Q9NRN7 2
Initiation of nuclear envelope ne reformation 0.5134743774948256 1.4912957749694309 0.1358838577179946 1.0 0.9197957956473886 17 P06493,P42166,Q8IXJ6,O95067,P50402,P63151,P30153,Q86XL3 8
Mitochondrial protein import 0.5781026260689973 1.4891447398778377 0.1364492586638219 1.0 0.9197957956473886 36 P62072,P21796,O43615,Q99595,Q10713,Q8N4H5,Q9NS69,Q13505,O14925,O60830 10
Slc mediated transmembrane transport 0.5367549050377128 1.4540676745161127 0.145927544614151 1.0 0.9334956599181652 25 Q8TAD4,P35613,Q9UBX3,O00400,Q70HW3,P30825 6
Traf6 mediated nf kb activation 0.7148367931778491 1.4528461972548743 0.1462664620275351 1.0 0.9334956599181652 4 P05067,Q7Z434 2
Tnf signaling 0.6643033284159527 1.434781646099468 0.1513493296362789 1.0 0.9334956599181652 6 O95429 1
Mrna decay by 3 to 5 exoribonuclease 0.5111803648542439 1.4327859981341189 0.1519190039792941 1.0 0.9334956599181652 14 Q96C86,Q969T7 2
Processing of smdt1 0.5230680324156345 1.422408478842954 0.1549077031339409 1.0 0.9334956599181652 13 Q9H4I9 1
Nuclear signaling by erbb4 0.7051941380002515 1.410219089526973 0.1584750007984572 1.0 0.9334956599181652 4 Q92542,P16949 2
Intra golgi traffic 0.4970211967183874 1.4069840326107832 0.1594321235959368 1.0 0.9334956599181652 16 O00461,O95249,Q8TBA6 3
Ripk1 mediated regulated necrosis 0.5563070943103867 1.3996777735427337 0.1616098325354202 1.0 0.9334956599181652 10 Q16543,O00560 2
Nephrin family interactions 0.5763258036060701 1.3896657058865074 0.1646304132275595 1.0 0.9334956599181652 8 O14936,P12814,O43707 3
Formation of atp by chemiosmotic coupling 0.5391993482332642 1.3682933118255876 0.1712202834502538 1.0 0.9334956599181652 11 O75964 1
Flt3 signaling 0.6920539070970939 1.3520450418098902 0.1763609067968952 1.0 0.9334956599181652 4 P51692 1
Trafficking and processing of endosomal tlr 0.8186957647708963 1.348675462649301 0.1774412302500194 1.0 0.9334956599181652 3 P07858 1
Signaling by fgfr1 in disease 0.5333200309736265 1.333775480282959 0.1822774490902388 1.0 0.9334956599181652 11 P51692,O95684,O95429 3
Fgfr1 mutant receptor activation 0.5333200309736265 1.333775480282959 0.1822774490902388 1.0 0.9334956599181652 11 P51692,O95684,O95429 3
Signaling by hippo 0.600633914421548 1.315265308838782 0.1884207528387942 1.0 0.942783983518299 7 O14641,Q9UDY2,P62258,P42574,Q4VCS5,P31946 6
Intrinsic pathway for apoptosis 0.4972557749355577 1.3099502443716315 0.1902126681457874 1.0 0.9434927040676264 20 Q9Y3B8 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.507770892107839 1.3087926814726487 0.1906045866803285 1.0 0.9434927040676264 23 P14174,P11233,P52597,O14979,Q13126 5
Formyl peptide receptors bind formyl peptides and many other ligands 0.8078454504655217 1.3060701743476064 0.1915286946073822 1.0 0.9446931342556288 3 Q9NRV9 1
Glycerophospholipid biosynthesis 0.5265221446125865 1.2977120489677474 0.1943863017233171 1.0 0.9486599091144986 29 Q8N2A8,Q96N66,Q9HCL2,Q9BZF1,Q8NCC3,P35790,Q9NQZ5,Q8IV08 8
Synthesis of pg 0.8019291551201059 1.282843980062481 0.1995467424100789 1.0 0.9565064252584142 3 Q8IV08 1
Signaling by erbb4 0.5924630060744719 1.274102603406562 0.2026270559115519 1.0 0.9565064252584142 7 Q96J02,P62993,Q92542,P16949 4
Glycogen synthesis 0.6515781686443248 1.271426561298011 0.2035769382741119 1.0 0.9565064252584142 5 Q96G03,P46976,P36871 3
Striated muscle contraction 0.6502610358401273 1.265408258831022 0.2057250161702981 1.0 0.9565064252584142 5 P28289,P08670,P67936 3
Pi metabolism 0.4824550022350016 1.2598426162307337 0.2077261428591506 1.0 0.9565064252584142 18 Q8NEB9,Q10713,Q9BTU6 3
Vitamin d calciferol metabolism 0.7929724596391226 1.2476968606957335 0.2121420913925495 1.0 0.9640293071149958 3 P04062,Q99538 2
Interleukin 12 signaling 0.5040382019598377 1.2380902701258971 0.2156825912340112 1.0 0.9741544191990272 25 P14174,P11233,P07237,P52597,O14979,Q9UL46,Q13126 7
Metabolism of fat soluble vitamins 0.6436524220565009 1.2352079535007303 0.2167531199700394 1.0 0.9741544191990272 5 Q6NUM9,Q8N0U8,P01130 3
Ire1alpha activates chaperones 0.5103487931944622 1.2349470555915758 0.2168502091178341 1.0 0.9741544191990272 27 O14773,Q06210,O76024,P51858,Q9Y5M8,Q9NWM8,O43909,Q14203,O95070,P43307,O43731,Q8N6T3 12
Ctla4 inhibitory signaling 0.5806771142312628 1.2146487742746213 0.2245000778235066 1.0 1.0 7 P30154 1
Regulated necrosis 0.4715408430113817 1.2114306007274227 0.2257304173712169 1.0 1.0 17 Q8WUM4,Q8WUX9,O00560,Q16543 4
Role of phospholipids in phagocytosis 0.6370574509498497 1.205068273829459 0.2281769462762695 1.0 1.0 5 Q8IV08 1
Cargo concentration in the er 0.4627170245365917 1.2022654314983934 0.2292607056177869 1.0 1.0 15 P49755,Q96PC5,P49257,O95487,Q15363,Q15436 6
Apoptotic factor mediated response 0.576845172291661 1.1953045720690954 0.2319680541037798 1.0 1.0 7 P28482,Q07812,P55210,Q9NR28 4
Synthesis of substrates in n glycan biosythesis 0.4685857020226727 1.1916086011177265 0.2334147508782982 1.0 1.0 17 Q86SQ9,Q86YN1,P10619,Q11206 4
Translation of replicase and assembly of the replication transcription complex 0.6337901875569703 1.1901380295373372 0.2339921452346003 1.0 1.0 5 Q8NEB9 1
Sphingolipid de novo biosynthesis 0.5069375732719741 1.178337032089574 0.2386622699411755 1.0 1.0 11 P51648,Q9Y5P4,Q06136,O15269,Q96G23 5
Signalling to ras 0.7739348870195939 1.1731000376796263 0.2407556914133994 1.0 1.0 3 P11233 1
Interleukin 12 family signaling 0.5040990334068857 1.1716176781971002 0.2413505872811185 1.0 1.0 28 P14174,P27824,P11233,Q99439,P07237,P52597,O14979,Q9UL46,Q13126 9
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.649411332355486 1.163043634509236 0.2448117991924414 1.0 1.0 4 P09429,P05067 2
Hedgehog ligand biogenesis 0.5326489595742406 1.1525030388796134 0.2491144217187311 1.0 1.0 38 P49721,P61289,P60900,P20618,P07237,P62195,P28070,P51665,P28072,O00231,Q99436,P28074,Q9UBV2,Q9UL46 14
Synthesis of dolichyl phosphate 0.9566455696202528 1.1500087987796774 0.2501402473169232 1.0 1.0 2 Q86SQ9 1
Gastrin creb signalling pathway via pkc and mapk 0.6238982395640644 1.1449522117862831 0.2522289538240128 1.0 1.0 5 P51812,P62993,Q15418 3
Constitutive signaling by egfrviii 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Signaling by erbb2 ecd mutants 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Signaling by egfr in cancer 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Constitutive signaling by overexpressed erbb2 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Signaling by erbb2 in cancer 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Constitutive signaling by ligand responsive egfr cancer variants 0.7658319679001961 1.141417639895448 0.2536961674446965 1.0 1.0 3 Q16543 1
Cristae formation 0.475391815101565 1.140381923935768 0.254127220301287 1.0 1.0 21 Q13505,O75964 2
Signaling by egfr 0.5099929495616266 1.1348728760270534 0.2564285861263964 1.0 1.0 10 P62993,Q92783 2
Late endosomal microautophagy 0.509567871249182 1.132434757635404 0.2574516990039597 1.0 1.0 10 Q8WUX9,P08670,Q9H9H4 3
Activation of nmda receptors and postsynaptic events 0.4725169389288899 1.121217360520273 0.2621953517707731 1.0 1.0 21 P52292,Q92796,O14936,Q14168,Q12959,P51812,P07196,P10644 8
Synthesis of pc 0.6160101755616219 1.1089516717155945 0.2674510311082256 1.0 1.0 5 P35790 1
Peptide hormone metabolism 0.4729451354518433 1.108223466375361 0.2677653187183475 1.0 1.0 13 Q8TAD4,P67812 2
Rab geranylgeranylation 0.4659028302744262 1.1007929615158352 0.2709867757812021 1.0 1.0 20 P53611,Q9BZG1,Q9H0U4,Q13637,P20339,P61106,Q969Q5,P61019,P61026,P62820,P61020,P20340 12
Signaling by kit in disease 0.5575496913819458 1.0978721392592166 0.2722603252566773 1.0 1.0 7 P51692 1
Depolymerisation of the nuclear lamina 0.5217492235007716 1.09406455660555 0.2739266658701285 1.0 1.0 8 P06493,P20700,P42166,P50402 4
Miscellaneous transport and binding events 0.5904382237720098 1.0872146565721987 0.2769419549332714 1.0 1.0 6 Q8N4V1 1
Metalloprotease dubs 0.610634324372058 1.0844408007116229 0.2781694016064306 1.0 1.0 5 Q92783 1
Nod1 2 signaling pathway 0.6092391305109539 1.078083406550539 0.2809965360486699 1.0 1.0 5 Q13685,Q96J02 2
Cross presentation of soluble exogenous antigens endosomes 0.5109837007405595 1.0699931433717775 0.2846223950278079 1.0 1.0 35 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Degradation of axin 0.5109837007405595 1.0699931433717775 0.2846223950278079 1.0 1.0 35 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Endosomal vacuolar pathway 0.7469560429297821 1.067846624903639 0.2855897024002625 1.0 1.0 3 Q9UIQ6 1
Downstream signaling events of b cell receptor bcr 0.5178255696595705 1.0554911553996569 0.2912007524671991 1.0 1.0 38 P49721,P62942,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 14
Platelet sensitization by ldl 0.6011723972463177 1.041363958236985 0.2977066632673333 1.0 1.0 5 P30154 1
Recruitment of mitotic centrosome proteins and complexes 0.496763547628052 1.0380175437334311 0.2992618874925252 1.0 1.0 32 Q15691,P21127,Q13409,Q9H6D7,Q9BSJ2,O75935,O43805,O94927,Q68CZ6,O95684,P30153,Q96CS2,P41208,P23258 14
Regulation of runx3 expression and activity 0.5090495461063178 1.0373523474994168 0.2995716778217976 1.0 1.0 36 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Diseases associated with glycosylation precursor biosynthesis 0.5102039223957241 1.031383815814082 0.3023608672755502 1.0 1.0 8 P10619 1
Cargo trafficking to the periciliary membrane 0.4517853306024292 1.0303875925994523 0.3028280952590592 1.0 1.0 19 P78371,O43924,Q10713 3
Interleukin 15 signaling 0.7365474833970493 1.0274592975192165 0.3042042419081632 1.0 1.0 3 P51692 1
Signal regulatory protein family interactions 0.6169364791142667 1.0197013915500397 0.3078701015220448 1.0 1.0 4 P62993 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4491729403260895 1.01294564219765 0.3110861256788215 1.0 1.0 19 P10619,P16278,Q86YN1,Q11206,O75340,Q9Y5P6,Q86SQ9 7
Keratan sulfate biosynthesis 0.7323450720063102 1.011197626422506 0.3119218516175213 1.0 1.0 3 Q11206 1
Golgi cisternae pericentriolar stack reorganization 0.4668436147830304 1.0022180753600192 0.3162382797198126 1.0 1.0 12 P06493,Q08379,Q9H0U4,Q9H8Y8,O95067,P61019,P62820 7
Attachment of gpi anchor to upar 0.592421624916105 1.001618973769704 0.3165276535742465 1.0 1.0 5 Q9H490,O43292 2
Synthesis of pips at the plasma membrane 0.5045650211865325 1.0007982274766845 0.3169243666769548 1.0 1.0 8 Q9BTU6 1
Interleukin 2 family signaling 0.5920743315122157 1.00004382680463 0.3172892987203495 1.0 1.0 5 P51692 1
Ncam signaling for neurite out growth 0.5715370451332876 0.9984037758696074 0.3180836034061292 1.0 1.0 6 P28482,P62993,Q13813 3
Metabolism of polyamines 0.5057190283493922 0.9958905623137466 0.319303321355332 1.0 1.0 37 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Protein protein interactions at synapses 0.4300831846113968 0.9825478622979668 0.3258300156612181 1.0 1.0 15 O14936,Q14168,O95197 3
Degradation of the extracellular matrix 0.4829597809879516 0.9799301182404856 0.3271206147994936 1.0 1.0 10 P07858,P04632,Q92542,P35613 4
Signaling by cytosolic fgfr1 fusion mutants 0.4908928898557094 0.9732655824979276 0.3304213234112261 1.0 1.0 9 P51692,O95684 2
Synaptic adhesion like molecules 0.4985725666549287 0.968329376137939 0.3328798981531906 1.0 1.0 8 Q92796,O95197 2
Rsk activation 0.6051603396297911 0.9680650297108504 0.3330118934381643 1.0 1.0 4 P51812,Q15418 2
Interleukin 1 signaling 0.5123717961240367 0.9628613125284828 0.3356171267032735 1.0 1.0 41 P49721,Q15008,P62191,P20618,P28074,P09429,P62195,P28072,P25787,P61289,P17980,P28070,P61088,P05067,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 21
Asymmetric localization of pcp proteins 0.4993683402930704 0.954486155422304 0.3398376139519479 1.0 1.0 37 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Post translational protein modification 0.2540343907139714 0.9490209607978608 0.3426099515051717 1.0 1.0 383 Q13564,P20618,P24390,P61019,P28074,Q9H490,Q96K76,Q9NXR7,P10619,Q9BT78,Q8NFH4,P62195,O43292,O15155,O43731,Q86SQ9,P04066,P21796,P53611,O15498,Q9BUN8,Q04323,O95487,P45880,P41208,Q92783,Q9Y5P6,Q7Z434,P27824,O15027,O43852,P54725,O14579,P37198,Q14527,O95249,O60725,P49721,Q86YN1,Q13637,Q92905,O60858,P38435,Q9BTY2,P11047,Q9UER7,O75935,Q9BT22,Q96PC5,Q16763,P28072,Q9GZS3,Q9Y6Y8,Q8N6T3,P06493,Q93009,Q9BUF5,P28070,Q969Q5,Q99436,Q92643,P35606,Q15363,O76024,O00231,Q9BTE7,Q9Y3B3,Q11206,Q02818,Q9Y277,Q07065,Q92734,O43681,P60604,Q9UBV2,Q8N1F7,Q13409,P61289,Q99627,P05067,Q9UL46,P63208,O75381,P62820,Q9H9E3,Q10472,P16278,O43505,P49257,P50542,O43493,P61978,P07237,Q9BTX1,Q5SRI9,Q9UNS2,P60900,O75340,P61020 99
Stabilization of p53 0.495160391796507 0.9466634167542792 0.3438103176537779 1.0 1.0 36 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Assembly of the hiv virion 0.7097182652738183 0.9241791027239448 0.3553930738773383 1.0 1.0 3 Q9H9H4,Q99816 2
Phase i functionalization of compounds 0.4325474360763957 0.9228540080092024 0.3560832911536746 1.0 1.0 14 O43169,Q16850 2
Defective cftr causes cystic fibrosis 0.5027921945612405 0.9193684962957543 0.3579028616237434 1.0 1.0 40 P49721,P61289,P60900,P20618,Q9BUN8,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UBV2,Q9UL46 14
Er quality control compartment erqc 0.7080998130915597 0.9179948082913932 0.3586215839019335 1.0 1.0 3 O60858 1
Signaling by notch1 0.4885135958244243 0.9139397236569662 0.3607485191222164 1.0 1.0 8 Q96J02,P63208 2
Negative regulation of notch4 signaling 0.4977219782771687 0.905359220832988 0.3652751120925943 1.0 1.0 39 P49721,Q15008,P62191,P63104,P20618,O75832,P28074,P62195,P28072,P25787,P61289,P17980,P28070,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 20
Cytochrome p450 arranged by substrate type 0.7027648865329967 0.8976526209716889 0.3693707759067774 1.0 1.0 3 Q16850 1
Folding of actin by cct tric 0.4852729521247212 0.8964558287769524 0.3700093614105038 1.0 1.0 8 P48643,Q99832,P78371,P49368 4
Bbsome mediated cargo targeting to cilium 0.548463580214615 0.8906715183875309 0.3731054188051614 1.0 1.0 6 P48643,P78371,P49368 3
Fceri mediated nf kb activation 0.4972217220876144 0.8833004946391282 0.3770739366286306 1.0 1.0 40 P49721,Q15008,P62191,P20618,P28074,P62195,P28072,P25787,P61289,P17980,P28070,P61088,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 19
Phospholipid metabolism 0.513094717843368 0.8773793331332913 0.3802806346907204 1.0 1.0 46 Q8N2A8,Q9BTU6,Q96N66,Q8IV08,Q10713,Q9HCL2,Q9BZF1,Q8NCC3,P35790,Q9NQZ5,Q99829,Q8NEB9 12
Beta catenin phosphorylation cascade 0.5131671627103429 0.8748053712479871 0.3816798141718376 1.0 1.0 7 P30154 1
Signaling by ctnnb1 phospho site mutants 0.5131671627103429 0.8748053712479871 0.3816798141718376 1.0 1.0 7 P30154 1
Stat5 activation 0.6965365432836153 0.8739926282327166 0.3821222683030081 1.0 1.0 3 P51692 1
Signaling by flt3 itd and tkd mutants 0.6965365432836153 0.8739926282327166 0.3821222683030081 1.0 1.0 3 P51692 1
Stat5 activation downstream of flt3 itd mutants 0.6965365432836153 0.8739926282327166 0.3821222683030081 1.0 1.0 3 P51692 1
Fgfr2 alternative splicing 0.4245508285414602 0.8728129339362046 0.3827650486361222 1.0 1.0 18 P35269,P31943,P52272,P52597 4
Disassembly of the destruction complex and recruitment of axin to the membrane 0.4805610433425104 0.8710749862824484 0.3837132109161847 1.0 1.0 8 P30154 1
Pp2a mediated dephosphorylation of key metabolic factors 0.6949653222630459 0.868039907885197 0.3853724858699197 1.0 1.0 3 P30154 1
Maturation of protein 3a 0.8772151898734172 0.867022810070737 0.385929511847999 1.0 1.0 2 Q11206 1
Interleukin 1 family signaling 0.5031483512998306 0.8664788483200184 0.386227620814044 1.0 1.0 43 P49721,Q15008,P62191,P20618,P28074,P09429,P62195,P28072,P25787,P61289,P17980,P28070,P61088,P05067,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 21
G1 s dna damage checkpoints 0.4880368364543087 0.8616952897437075 0.3888552182754732 1.0 1.0 38 P49721,Q15008,P62191,P61289,P60900,Q99436,P20618,P17980,P28070,P62195,P51665,P28072,O00487,O00231,P25787,P28074,Q9UL46 17
Degradation of gli1 by the proteasome 0.4904694279320488 0.8584510648676656 0.3906434406731585 1.0 1.0 39 P49721,P61289,Q96J02,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 14
Intraflagellar transport 0.4759501828558775 0.8462914947432564 0.397390151408324 1.0 1.0 8 A0AVF1 1
Cellular response to hypoxia 0.485263031132861 0.8437924879964582 0.3987853739644911 1.0 1.0 38 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q9Y241,Q99436,P28074,Q9UL46 13
Piwi interacting rna pirna biogenesis 0.4582160712676987 0.8389690954181521 0.4014866521979623 1.0 1.0 10 Q9Y2W6 1
Small interfering rna sirna biogenesis 0.5743947382796752 0.8346308130989909 0.4039256075697894 1.0 1.0 4 Q99598,Q15631 2
Notch3 activation and transmission of signal to the nucleus 0.6861054904734045 0.8346026061490053 0.4039414943053936 1.0 1.0 3 P67809 1
Signaling by notch4 0.494136126552438 0.8265846915447997 0.408472497068806 1.0 1.0 42 P49721,Q15008,P62191,P63104,P20618,O75832,Q92542,P28074,P62195,P28072,P25787,P61289,P17980,P28070,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 21
Caspase mediated cleavage of cytoskeletal proteins 0.5032340664140279 0.8253910398740923 0.4091496202241023 1.0 1.0 7 P08670,P55210,Q13813 3
Plasma lipoprotein remodeling 0.8639240506329108 0.8211347438003483 0.4115695216963659 1.0 1.0 2 Q9BU23 1
Regulation of ras by gaps 0.4750038667024351 0.8160614881439366 0.4144649690015578 1.0 1.0 36 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46 12
Fceri mediated ca 2 mobilization 0.5700450858734916 0.815989267967406 0.414506273829756 1.0 1.0 4 O43865 1
Cyclin a cdk2 associated events at s phase entry 0.4890783157055404 0.8123509849746745 0.4165902627953621 1.0 1.0 41 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 13
Scf skp2 mediated degradation of p27 p21 0.4890783157055404 0.8123509849746745 0.4165902627953621 1.0 1.0 41 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 13
Hiv transcription initiation 0.4038849957027614 0.807501036697775 0.419377877481665 1.0 1.0 15 Q92804,P35269 2
Activation of kainate receptors upon glutamate binding 0.5653578975413518 0.7959766893318204 0.4260455845166979 1.0 1.0 4 Q92796 1
Prolactin receptor signaling 0.5653371810612906 0.7958884192200926 0.4260968929893034 1.0 1.0 4 P63208 1
Sulfur amino acid metabolism 0.4499069372574067 0.7920164933002724 0.4283510593099664 1.0 1.0 10 Q9UBX3,Q13126 2
Cell surface interactions at the vascular wall 0.4116133848327221 0.7873637101708423 0.4310689840950901 1.0 1.0 18 P08195,P14174,P35613 3
Dectin 1 mediated noncanonical nf kb signaling 0.479125645204838 0.7855350468922021 0.4321399302694317 1.0 1.0 39 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 13
Tnfr2 non canonical nf kb pathway 0.4791256452048381 0.7855350468922018 0.432139930269432 1.0 1.0 39 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 13
Spry regulation of fgf signaling 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Signaling by fgfr1 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Negative regulation of fgfr1 signaling 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Signaling by fgfr3 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Signaling by fgfr4 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Negative regulation of fgfr2 signaling 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Negative regulation of fgfr3 signaling 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Negative regulation of fgfr4 signaling 0.5255299578792502 0.7848555057291318 0.4325382920700906 1.0 1.0 6 P30153 1
Regulation of runx2 expression and activity 0.4836156569765792 0.7773920793026219 0.4369274841259134 1.0 1.0 41 P49721,Q15008,P62191,P20618,P28074,P62195,P28072,P25787,P61289,P17980,P28070,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487,P49841 19
Transcriptional regulation by runx3 0.4864439359363159 0.7773389924454791 0.4369587957512566 1.0 1.0 42 P49721,P25440,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46 13
Regulation of pten stability and activity 0.4776579588722146 0.7761487989286048 0.4376611334047746 1.0 1.0 39 P49721,Q15008,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46 13
Tcr signaling 0.488190460901083 0.7705803183280034 0.4409557308592349 1.0 1.0 43 P49721,Q15008,P62191,P20618,P28074,Q13153,P62195,P28072,P25787,P61289,P17980,P28070,P61088,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487 20
Cytosolic iron sulfur cluster assembly 0.5199240314010163 0.7592547621453716 0.4477001730693164 1.0 1.0 6 O75027 1
Degradation of dvl 0.4688035004418635 0.7571565971569987 0.448956049639057 1.0 1.0 37 P49721,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46 12
Signalling to erks 0.4583229741747509 0.7521611638285769 0.4519541454203541 1.0 1.0 8 P31946,P62993,P46108,P11233 4
G1 s specific transcription 0.434100390418143 0.7508333634296825 0.4527529477863403 1.0 1.0 11 P06493,P00374,Q9Y619 3
Auf1 hnrnp d0 binds and destabilizes mrna 0.4760134281684177 0.7472047830685109 0.4549399573337069 1.0 1.0 40 P49721,P61289,Q14103,P60900,P20618,P28070,P62195,P11940,P51665,P28072,O00231,Q99436,P28074,Q9UL46 14
Regulation of hmox1 expression and activity 0.4866340978423606 0.7430375741350035 0.4574589322293754 1.0 1.0 44 P49721,Q15008,P61289,P60900,Q8TCT9,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208,P09601 16
Synthesis of pips at the early endosome membrane 0.5322602874842912 0.7330658367624135 0.4635182755418794 1.0 1.0 5 Q8NEB9 1
Sealing of the nuclear envelope ne by escrt iii 0.4544707714354895 0.7317496951154153 0.4643213583135517 1.0 1.0 8 Q8WUX9,Q9BUF5,Q13885 3
Toll like receptor cascades 0.4197804405822407 0.7278166853736112 0.4667258092198456 1.0 1.0 23 P30154,P05067,Q99538,P07858,Q8NEB9,P63208 6
Selective autophagy 0.438154581669437 0.7190531635006815 0.4721081638477526 1.0 1.0 29 P21796,Q13409,P08670,Q9NS69,Q8N4H5 5
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.481527122819854 0.7185742804565523 0.4724032650807386 1.0 1.0 7 P62993,Q8NEB9 2
Response to elevated platelet cytosolic ca2 0.4474336806474867 0.7178443187638742 0.4728532834464234 1.0 1.0 32 Q12846,Q9Y6I9,P07602,P05067,O43852,Q08380,Q8NBM8,Q9NUQ9 8
Glycogen metabolism 0.4427864034013246 0.7085666582410833 0.4785934330133936 1.0 1.0 9 P06737,P10253,Q96G03,P46976,P36871 5
Myd88 independent tlr4 cascade 0.3878553912747433 0.7019742347833867 0.4826952316302138 1.0 1.0 15 P09429,P51812,P05067,P30154,P30153,P63208,Q15418 7
Reduction of cytosolic ca levels 0.5402515894340668 0.6903492002279228 0.4899746145943688 1.0 1.0 4 P23634,P30626 2
E3 ubiquitin ligases ubiquitinate target proteins 0.3845031955164921 0.6801315097443171 0.496421194525861 1.0 1.0 15 P50542,Q14527,O75381,Q9GZS3 4
Translation of sars cov 1 structural proteins 0.4441101787438456 0.6772066543391797 0.4982748463250823 1.0 1.0 8 Q10472,Q11206 2
Epha mediated growth cone collapse 0.4347309222505671 0.6651566587479224 0.5059502985132216 1.0 1.0 9 Q15375,O75116,Q13464,P60660 4
Signaling by insulin receptor 0.3892107920451424 0.6644148166240931 0.5064248523375765 1.0 1.0 17 Q93050,Q8NEB9 2
Anchoring of the basal body to the plasma membrane 0.4385154946351733 0.6613274424030645 0.5084023462070801 1.0 1.0 32 Q15691,Q13409,Q9H6D7,O75935,O43805,O94927,Q68CZ6,O95684,P30153,Q96CS2,P41208,P23258 12
Organic anion transporters 0.8148734177215181 0.657336880606593 0.5109643273542026 1.0 1.0 2 Q9UBX3 1
Insulin receptor recycling 0.425446192919238 0.6556221664462771 0.512067259578395 1.0 1.0 10 Q93050 1
Hedgehog on state 0.4582981165972886 0.6536471469209805 0.5133391617745444 1.0 1.0 39 P49721,P61289,Q96J02,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46 13
Neurexins and neuroligins 0.4307483921355732 0.6438391313933377 0.5196797557948867 1.0 1.0 9 O14936,Q14168 2
Signaling by fgfr 0.4090337811788495 0.6375945533353621 0.5237376421264082 1.0 1.0 24 P35269,P52597,P31943,Q01085,P30153,P52272 6
Signaling by fgfr2 0.4090337811788495 0.6375945533353621 0.5237376421264082 1.0 1.0 24 P35269,P52597,P31943,Q01085,P30153,P52272 6
Signaling by the b cell receptor bcr 0.4667620224686793 0.6355738937768427 0.5250541896287086 1.0 1.0 43 P49721,P62942,P61289,P60900,P62993,P20618,P28070,P62195,O43865,P51665,P28072,O00231,Q99436,P28074,Q9UL46,P63208 16
Basigin interactions 0.4643192267457086 0.6354432775929473 0.52513934999953 1.0 1.0 7 P35613 1
Growth hormone receptor signaling 0.4621236133121802 0.6249590978169572 0.5319979034405338 1.0 1.0 7 P27361,P07948,P18031,P28482,P40763,P51692 6
Polo like kinase mediated events 0.5055784880158541 0.6185043998414936 0.5362428984012122 1.0 1.0 5 Q99640 1
Cargo recognition for clathrin mediated endocytosis 0.4313224746992607 0.6162257344628883 0.537745545990449 1.0 1.0 32 Q9UNS2,Q14108,Q9BT78,P62993,Q96D71,Q99627,Q92905,Q92783,Q9UMX0,O14657,O43493 11
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5209555418236986 0.6113833244566512 0.5409458396371893 1.0 1.0 4 P30154 1
Signaling by wnt in cancer 0.422103796822477 0.5979376687605131 0.549881524256977 1.0 1.0 9 P30154 1
Formation of tubulin folding intermediates by cct tric 0.4065946153619801 0.5944587207981943 0.5522053436380623 1.0 1.0 11 Q9BUF5,Q99832,P49368,P78371,P48643,Q13885 6
Activated notch1 transmits signal to the nucleus 0.7939873417721509 0.590888964550977 0.5545948205492406 1.0 1.0 2 Q96J02 1
Noncanonical activation of notch3 0.7939873417721508 0.590888964550977 0.5545948205492406 1.0 1.0 2 P67809 1
Degradation of beta catenin by the destruction complex 0.470424137029158 0.5908860441528017 0.5545967774355538 1.0 1.0 47 P49721,P61289,P60900,P20618,P28070,P62195,P30154,P51665,P28072,O00231,P30153,Q99436,P28074,Q9UL46,P63208 15
Response of eif2ak1 hri to heme deficiency 0.6182336182336138 0.5883052457512544 0.5563274251901609 1.0 1.0 3 P05198,P08243 2
The role of gtse1 in g2 m progression after g2 checkpoint 0.4662684511902255 0.5818292331962638 0.5606817111372213 1.0 1.0 46 P49721,Q15008,P62191,P20618,P28074,Q15691,P62195,P28072,P25787,P06493,P61289,Q9BUF5,P17980,P28070,Q99436,Q9UL46,P60900,P51665,O00231,O00487,O95067,Q13885 22
Death receptor signalling 0.3898320633829328 0.5801306132905009 0.561826540769683 1.0 1.0 21 O95429,P62258,Q9NQC3,Q96BN8,Q92542,Q8TCT8,Q92974 7
Glycogen breakdown glycogenolysis 0.4792820064656385 0.5781784195082391 0.5631436670745813 1.0 1.0 6 P46976,P10253 2
Hedgehog off state 0.46556759183196 0.5775370290418075 0.5635767318374516 1.0 1.0 46 P49721,Q15008,P62191,P20618,P28074,Q96J02,P62195,P28072,P25787,P10644,P61289,Q9BUF5,P17980,P28070,Q99436,Q9UL46,P63208,P60900,P51665,O00231,O00487,P49841,Q13885 23
G alpha i signalling events 0.4026499981808114 0.5767261736830218 0.5641244483692822 1.0 1.0 25 O43865,P07602,P30154,P05067,P30153,Q9NRV9 6
Aurka activation by tpx2 0.4245019088058208 0.5739193789087914 0.5660223587130524 1.0 1.0 32 Q15691,Q13409,Q9H6D7,O75935,O43805,O94927,Q68CZ6,O95684,P30153,Q96CS2,P41208,P23258 12
Uch proteinases 0.4523314660443318 0.5638590474564763 0.5728500626121034 1.0 1.0 42 P49721,Q15008,P61289,P60900,P20618,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UL46,Q9Y265 14
Recruitment of numa to mitotic centrosomes 0.4317897712265579 0.5625588368861554 0.5737353284223663 1.0 1.0 35 Q15691,P06493,Q13409,Q9H6D7,Q9BSJ2,O75935,O43805,P62258,Q13561,Q9BUF5,O94927,Q68CZ6,Q14203,O95684,P30153,Q96CS2,P41208,P23258 18
Transferrin endocytosis and recycling 0.3999004521956861 0.5572741990942081 0.5773401009760009 1.0 1.0 11 Q93050 1
Insulin processing 0.4201403909143989 0.5535370303937434 0.579895731156574 1.0 1.0 8 Q8TAD4 1
Ca2 pathway 0.4899155585908401 0.5532846372182398 0.5800685190792336 1.0 1.0 5 Q9HCE1 1
Aryl hydrocarbon receptor signalling 0.6071541627097136 0.5503047689960563 0.5821103537898786 1.0 1.0 3 O00170,Q15185 2
Mastl facilitates mitotic progression 0.4717731998688522 0.5458386095767048 0.5851768807154731 1.0 1.0 6 P30154,P30153 2
Runx2 regulates bone development 0.5044331855604658 0.5457007233551747 0.5852716746329722 1.0 1.0 4 P28482,Q96PK6,P12931 3
Dna damage reversal 0.5043907009270627 0.545534435111981 0.5853860038394034 1.0 1.0 4 Q9H1I8 1
Shc related events triggered by igf1r 0.7775316455696191 0.5402320770642631 0.5890369937622362 1.0 1.0 2 P62993 1
Toll like receptor tlr1 tlr2 cascade 0.3623831500991049 0.5386734913763351 0.590112167991447 1.0 1.0 15 P09429,P51812,P05067,P30154,P30153,P63208,Q15418 7
Transcriptional regulation by runx2 0.4677822030071622 0.5269471961947566 0.5982302578280874 1.0 1.0 50 P49721,Q15008,P62191,P20618,P28074,P62195,P28072,P25787,P06493,P61289,P17980,P28070,Q99436,Q9UL46,P63208,Q96PK6,P60900,P51665,O00231,O00487,P49841 21
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3980994564172793 0.5080032049121217 0.6114510956185937 1.0 1.0 10 Q96DE5 1
Rac2 gtpase cycle 0.4192672743255313 0.5047722045096563 0.6137188404732412 1.0 1.0 34 O15173,P49257,Q8TAA9,Q68EM7,Q13505,P50402,Q86XL3 7
Clec7a dectin 1 signaling 0.4500744335415788 0.5001739796585103 0.6169525783701086 1.0 1.0 45 P49721,Q15008,P62191,P20618,P28074,P62195,P28072,P25787,P61289,P17980,P28070,P61088,Q99436,Q9UL46,P63208,P60900,O43865,P51665,O00231,O00487 20
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.7617088607594924 0.4931018088986951 0.6219406527990878 1.0 1.0 2 Q15404 1
Abc transporter disorders 0.438964654798249 0.4833017399739465 0.6288815047877321 1.0 1.0 42 P49721,Q15008,P61289,P60900,P20618,Q9BUN8,P28070,P62195,P51665,P28072,O00231,Q99436,P28074,Q9UBV2,Q9UL46 15
Signal attenuation 0.5866630113033796 0.4821765552377652 0.6296805300604309 1.0 1.0 3 P62993 1
Signaling by erythropoietin 0.4860671962927994 0.4752121404822442 0.6346357746432396 1.0 1.0 4 P51692 1
Apc c cdc20 mediated degradation of cyclin b 0.377034750882204 0.4734364656889283 0.6359018189103331 1.0 1.0 12 Q16763,Q96DE5,Q9UJX3 3
Fc epsilon receptor fceri signaling 0.4554292665738911 0.4687298226855537 0.6392627672583182 1.0 1.0 49 P49721,Q15008,P62191,P62993,P20618,P28074,Q13153,P62195,P28072,P25787,P61289,P17980,P28070,P61088,Q99436,Q9UL46,P63208,P60900,O43865,P51665,O00231,O00487 22
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3761732862935263 0.4686817595877733 0.6392971268348542 1.0 1.0 12 Q96J02,P05067,Q7Z434 3
Sema4d induced cell migration and growth cone collapse 0.4517968793162393 0.4620289459593541 0.644060562887284 1.0 1.0 6 O75116,P60660,Q13464 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.3821181216392771 0.4607239594463557 0.6449966630299515 1.0 1.0 11 Q96DE5 1
Nrcam interactions 0.5747746438208265 0.4440805398888746 0.6569843553875279 1.0 1.0 3 Q92796 1
Ionotropic activity of kainate receptors 0.5747746438208265 0.4440805398888746 0.6569843553875279 1.0 1.0 3 Q92796 1
Dna damage recognition in gg ner 0.356668280290305 0.4393540654994092 0.6604050046051588 1.0 1.0 18 Q9UNS2,Q9BT78,Q99627,Q92905,P54725,P41208,Q9Y265 7
Abc family proteins mediated transport 0.4576180956529402 0.4364248981509827 0.6625284776150164 1.0 1.0 52 P49721,P61289,P40855,P60900,P20618,P28288,P28070,P62195,O75027,P28072,O00231,P08183,P28074,Q9UBV2,Q9UL46 15
Rhoa gtpase cycle 0.444033848899798 0.4328384274214198 0.665132154172539 1.0 1.0 47 Q9UDY2,Q15904,Q96HY6,O15173,O15498,Q5T8D3,P30519,P49257,Q8NBN3,Q8TAA9,P27105,P28288,Q9H0H5 13
Costimulation by the cd28 family 0.3449185392936056 0.4313403924220139 0.6662208845120166 1.0 1.0 15 P30154,P62993,P30153 3
Raf independent mapk1 3 activation 0.4589800443459021 0.4302910972021164 0.6669839024231623 1.0 1.0 5 P27361,P06493,P28482,Q99956 4
N glycan trimming and elongation in the cis golgi 0.7386075949367075 0.4273873653327076 0.6690972084924647 1.0 1.0 2 Q5SRI9 1
Irs mediated signalling 0.45582800953931 0.4182713264912696 0.6757487514278684 1.0 1.0 5 Q8NEB9 1
Coenzyme a biosynthesis 0.7332278481012646 0.4126548756827538 0.6798594899496422 1.0 1.0 2 Q13057 1
Copi dependent golgi to er retrograde traffic 0.4344596968234428 0.4085695264204179 0.6828555979187294 1.0 1.0 45 P24390,Q9H0H5,P49755,Q9NSK0,Q9P2W9,O43731,Q8N6T3,Q12981,O15260,Q9BUF5,P52732,P35606,Q15363,P33176,Q07866,Q86Y91,O14579,P62820,Q9Y3B3 19
Diseases of mitotic cell cycle 0.3438486258415904 0.4041534552848819 0.6860998782757766 1.0 1.0 16 Q9UER7,Q96DE5,Q9UJX3 3
Signaling by notch3 0.4126856560409487 0.3991813817879697 0.6897595607267655 1.0 1.0 7 P67809 1
Blood group systems biosynthesis 0.728164556962024 0.3989972268086946 0.6898952476492652 1.0 1.0 2 Q11206 1
Protein folding 0.3965659985438805 0.3890891550651301 0.6972101956544787 1.0 1.0 33 O95302,Q9UHV9,P67870,Q9BUF5,P04062,Q99471,P48643,P78371,P61758,Q99426,Q9Y2T2,O15212 12
Other interleukin signaling 0.4478155775412205 0.3882017254419072 0.6978667563881782 1.0 1.0 5 Q12846,Q13277 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.4616846105129581 0.386568425128966 0.699075737144256 1.0 1.0 4 P62993,P40763,O00459 3
Metabolism of nitric oxide nos3 activation and regulation 0.4466265441875242 0.3838008429933657 0.7011260632125138 1.0 1.0 5 P35270,Q9Y314,P07900,P50570 4
Signaling by notch1 pest domain mutants in cancer 0.4073958664128458 0.3765020433418939 0.706543696687693 1.0 1.0 7 P63208 1
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.3722242402962185 0.3755785267506556 0.7072302571083462 1.0 1.0 10 Q16763,Q93009,P60604,P45974 4
Pyroptosis 0.4064402958167298 0.3724424193382767 0.7095634758097376 1.0 1.0 7 P09429,Q8WUX9,Q07812 3
Ion channel transport 0.3773039961387526 0.3674962298011713 0.7132489035929432 1.0 1.0 28 Q96PU5,Q15904,Q9C0H2,P51790,Q93050,P35670,Q9HD20 7
Regulation of plk1 activity at g2 m transition 0.4074299453734496 0.3665762361782049 0.7139351368241582 1.0 1.0 38 Q15691,Q13409,Q9H6D7,O75935,O43805,O94927,Q68CZ6,O95684,O95067,P30153,Q96CS2,P41208,P63208,P23258 14
Notch4 activation and transmission of signal to the nucleus 0.7148734177215177 0.3641423280109352 0.7157517302364413 1.0 1.0 2 Q92542 1
N glycan trimming in the er and calnexin calreticulin cycle 0.3332434458728733 0.3624463383750925 0.7170185169956458 1.0 1.0 15 O60858,Q9UBV2,Q9BUN8,Q04323 4
Rac3 gtpase cycle 0.3914133032653093 0.359825907703963 0.71897732755476 1.0 1.0 33 O15173,O15498,P49257,Q8TAA9,Q68EM7,P50402,Q9H0H5,Q9UQB8 8
Deadenylation of mrna 0.3361474759083495 0.3591789259170967 0.7194612408663053 1.0 1.0 16 P11940,P23588,Q9UKZ1,Q14240 4
Signaling by hedgehog 0.4410954781181001 0.3565124044269036 0.7214568641797094 1.0 1.0 51 P49721,P61289,Q96J02,Q9BUF5,P20618,P60900,P07237,P62195,P28070,P51665,P28072,O00231,Q99436,P28074,Q9UBV2,Q9UL46,P63208,P10644 18
G alpha 12 13 signalling events 0.4011428718417794 0.350152156117848 0.7262245104608347 1.0 1.0 7 Q92888,Q92974,Q13464 3
Protein ubiquitination 0.3605868082729 0.3454683769983256 0.7297422800218851 1.0 1.0 24 Q93009,O75381,P60604,Q9GZS3,Q14527 5
Sars cov 1 infection 0.3337249344979492 0.3452776858766824 0.7298856204382722 1.0 1.0 16 Q8WUX9,Q8NEB9,Q11206 3
Creb phosphorylation 0.7069620253164544 0.3441070362281963 0.7307657915326169 1.0 1.0 2 P51812 1
Calnexin calreticulin cycle 0.375402334086629 0.3371363955113633 0.7360140821479435 1.0 1.0 8 O60858,Q9UBV2 2
Copii mediated vesicle transport 0.3811885111585518 0.3367633302987544 0.736295318175997 1.0 1.0 31 P49755,O15498,O15027,P49257,Q9H0U4,O95487,O15155,P62820,Q9Y6Y8,Q92734,Q15363,Q15436 12
Apc cdc20 mediated degradation of nek2a 0.3579075711058427 0.3359224319526965 0.7369293607694918 1.0 1.0 11 Q96DE5 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3579075711058427 0.3359224319526965 0.7369293607694918 1.0 1.0 11 Q96DE5 1
Insulin receptor signalling cascade 0.3974923972708821 0.3350111622717546 0.7376166660159269 1.0 1.0 7 Q8NEB9 1
Signaling by braf and raf1 fusions 0.3449469478838254 0.331787722466038 0.7400495556980966 1.0 1.0 20 P51114,Q9NRY5 2
Kinesins 0.3305087013715861 0.3270157668497628 0.7436559600447672 1.0 1.0 16 P33176,Q07866,Q86Y91,Q9BUF5,Q9NSK0,P52732,Q9H0H5 7
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3491353988133325 0.3250520380138879 0.7451416875935504 1.0 1.0 12 P67870,Q99832,P49368,P78371,P48643 5
Nade modulates death signalling 0.5345430292729265 0.3243471130292957 0.745675254841855 1.0 1.0 3 P62258 1
Arachidonic acid metabolism 0.3929275614752449 0.3163407073971795 0.7517439163137005 1.0 1.0 7 P09960,Q15165 2
Toll like receptor 9 tlr9 cascade 0.3349291148810497 0.3134666437865785 0.7539261589830146 1.0 1.0 18 P09429,P51812,P05067,P30154,P30153,Q8NEB9,P63208,Q15418 8
Metabolism of folate and pterines 0.3644248875777284 0.310817492240916 0.7559393710008109 1.0 1.0 9 Q9H2D1 1
Cilium assembly 0.4476370909959708 0.3105052160191022 0.7561767935656847 1.0 1.0 57 Q13409,Q9H6D7,A6NIH7,O75935,O43805,Q10713,O94927,Q68CZ6,O43924,P78371,Q96CS2,A0AVF1,P23258 13
Antigen presentation folding assembly and peptide loading of class i mhc 0.3233432092396616 0.3062046757400569 0.7594488125631307 1.0 1.0 15 P10321,Q9NZ08,O95487,Q03518 4
Cdc42 gtpase cycle 0.3723576575869887 0.3051390995524056 0.7602602131760279 1.0 1.0 30 O15498,P42166,Q9UQB8,P27105,Q8TAA9,Q68EM7,P42167,Q13153,Q9H0H5,Q86YQ8,P02786 11
C type lectin receptors clrs 0.4261135206210868 0.3024651885131438 0.7622974669565636 1.0 1.0 49 P49721,Q15008,P62191,P20618,P28074,Q13153,P62195,P28072,P25787,P61289,P17980,P28070,P61088,Q99436,Q9UL46,P63208,P60900,O43865,P51665,O00231,O00487 21
Cobalamin cbl vitamin b12 transport and metabolism 0.4210824408127195 0.2934687793888509 0.7691638599034405 1.0 1.0 5 P33527,Q99707,O14678 3
Thrombin signalling through proteinase activated receptors pars 0.4062103929024006 0.2865038286983933 0.7744922614480576 1.0 1.0 6 P27361,Q14344,Q9UBI6,P12931,P28482 5
Maturation of sars cov 2 nucleoprotein 0.417801710484641 0.2824957767616584 0.7775633844250605 1.0 1.0 5 P48729,Q96SB4,Q99873,P49841 4
Phosphorylation of the apc c 0.3333670895254141 0.279876548565629 0.7795722200191364 1.0 1.0 13 Q16763,Q96DE5,Q9UJX3 3
Interleukin 17 signaling 0.3390170495232226 0.2746055560273521 0.7836192972953797 1.0 1.0 12 P61088,P51812,P30154,P30153,P63208,Q15418 6
Negative regulators of ddx58 ifih1 signaling 0.38243348095411 0.2745936356840546 0.7836284564386025 1.0 1.0 7 Q96J02 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4201871351012861 0.2707608680268564 0.7865749587420798 1.0 1.0 49 P49721,P61289,P60900,P20618,Q9UJX3,P62195,P28070,Q16763,P28072,P51665,O00231,Q99436,P28074,Q9UL46,Q96DE5 15
Arms mediated activation 0.6749999999999985 0.2689508339053594 0.7879675178334766 1.0 1.0 2 P31946 1
Mapk6 mapk4 signaling 0.4137159892759392 0.2644646861380482 0.791421872747806 1.0 1.0 47 P49721,Q15008,P62191,P20618,P28074,Q13153,Q9HCE1,P62195,P28072,P25787,P06493,P61289,P17980,P28070,Q9NZI8,Q99436,Q9UL46,P60900,P51665,O00231,O00487 21
Transcriptional regulation by ventx 0.3224533692123388 0.2603950670823488 0.7945590476482547 1.0 1.0 14 Q96DE5,Q9HCE1,Q9UJX3 3
Nicotinamide salvaging 0.5100248407307162 0.2594341012573953 0.7953003211551535 1.0 1.0 3 P43490 1
Chylomicron assembly 0.669936708860758 0.257938518193289 0.7964543571941347 1.0 1.0 2 P07237 1
Pentose phosphate pathway 0.3778368153914973 0.2568533780014631 0.7972919622797401 1.0 1.0 7 P11413,P52209 2
Runx2 regulates osteoblast differentiation 0.5042735042734973 0.2451940527199269 0.8063061811079364 1.0 1.0 3 P28482,P12931 2
Cdt1 association with the cdc6 orc origin complex 0.3870332582594087 0.2407713778564464 0.8097323142667583 1.0 1.0 39 P49721,P61289,P60900,P20618,Q9Y619,P28070,P28072,O00231,P28074,Q9UL46 10
Mtor signalling 0.3248695296491015 0.2375877472431074 0.8122008547178261 1.0 1.0 13 Q9Y376,P23588,P62942,P06730 4
Protein localization 0.4780879183222794 0.2340360821947326 0.8149569668604022 1.0 1.0 78 O75874,Q99595,Q13505,P50542,O14925,P09601,P62072,O43681,P40855,Q10713,Q9NS69,Q8N4H5,O60830,P21796,O43615,Q9Y5Y5,Q15067,P05067,Q9Y5J9,P28288,Q9Y5J7,O75381,P51648,P46379 24
Negative regulation of mapk pathway 0.3418900532976074 0.2333931045775532 0.8154561670960649 1.0 1.0 10 Q99956,P31946,P28482,P30154,P30153 5
Plasma lipoprotein assembly remodeling and clearance 0.3233587865581924 0.2330555651368125 0.8157182587358087 1.0 1.0 19 Q9BU23,Q8WTV0,P07237,O15118,Q6PIU2,P01130 6
Association of tric cct with target proteins during biosynthesis 0.3160153218451569 0.2298896075658737 0.8181775520373484 1.0 1.0 17 O95302,Q99832,P04062,P78371,P48643,Q9Y2T2 6
Ephrin signaling 0.4006805159562438 0.2278030675935463 0.8197993417994063 1.0 1.0 5 O00560 1
Signaling by pdgfr in disease 0.3887832699619603 0.2267832499207112 0.8205922890133686 1.0 1.0 6 P42224,P62993,P40763,O00459,Q6UN15 5
Dag and ip3 signaling 0.3692869215422346 0.2247999091254742 0.8221349367757602 1.0 1.0 7 P52292,O43865 2
Thromboxane signalling through tp receptor 0.4059531348955002 0.2112991504141445 0.8326538458298616 1.0 1.0 4 Q13685,Q14344,Q9UBI6 3
Mtorc1 mediated signalling 0.3336825936542945 0.1979911890270689 0.843051957412807 1.0 1.0 10 P23588,P62942,P06730 3
Interferon gamma signaling 0.3334390862944053 0.196963399203034 0.8438561798853099 1.0 1.0 10 P19474,P42224,O15344,Q14258,P18031,Q06124,P10321,P29372,P01889 9
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.4817413045408219 0.1932564368452828 0.8467581414973735 1.0 1.0 3 Q9HCE1 1
Signaling by mapk mutants 0.6335443037974665 0.1864166236313585 0.8521180571449205 1.0 1.0 2 P28482 1
Recycling of eif2 gdp 0.3866301474510338 0.1863637250407937 0.8521595372822386 1.0 1.0 5 P49770 1
Signaling by scf kit 0.3349609069460378 0.1835979636373291 0.8543288607483486 1.0 1.0 9 P51692 1
Innate immune system 0.3091676245919906 0.18158904744641 0.8559052448149373 1.0 1.0 271 Q9BXS5,P49721,O75874,P16278,Q99439,P30519,P20618,P27105,Q9BTY2,P28074,P07858,P61158,Q99829,Q07065,O95298,P09601,P14174,P10619,O43681,P10253,O00571,Q96J02,P12956,P46976,P07602,P62195,P28072,Q99538,Q8IV08,Q8NEB9,P04066,P09960,O15260,P08236,P61289,P17900,Q13510,P28070,P30154,P05067,P10321,Q969Q5,Q9UL46,P63208,P06280,P42785,P60900,Q93050,P61020,O43865,O00264,Q9H7Z7,O00231,P78371,O00560,Q9UQB8 56
Transport and synthesis of paps 0.6306962025316437 0.1813977261965485 0.8560554035056223 1.0 1.0 2 Q8TB61 1
Dap12 interactions 0.3836709508045433 0.1780548335980703 0.8586799127093792 1.0 1.0 5 P10321 1
Orc1 removal from chromatin 0.4040248558879848 0.1755228785025426 0.8606687953782386 1.0 1.0 50 P49721,P61289,P60900,P20618,P33991,Q14566,Q9Y619,P28070,P28072,O00231,P28074,Q9UL46,P63208 13
Signaling by fgfr in disease 0.3209578331609592 0.1714232980990743 0.8638909366823853 1.0 1.0 22 P51692,P35269,O95684,O95429 4
Activation of caspases through apoptosome mediated cleavage 0.6237341772151881 0.1694881516525695 0.8654126911517086 1.0 1.0 2 P55210 1
Nicotinate metabolism 0.3884865264106692 0.1658481134221099 0.8682764813565913 1.0 1.0 4 P43490 1
Prevention of phagosomal lysosomal fusion 0.3882203926535761 0.1651943918490427 0.86879097927996 1.0 1.0 4 P20339,P51149,Q9H267 3
Cholesterol biosynthesis 0.2984891944063744 0.159366625417347 0.8733800318837732 1.0 1.0 16 Q15392,Q16850,P14324 3
Synthesis of udp n acetyl glucosamine 0.464161106794586 0.1571722585728154 0.8751090909963717 1.0 1.0 3 Q06210 1
Interleukin 6 signaling 0.4586894586894508 0.1467586009979906 0.8833225623990013 1.0 1.0 3 P40763,P42224 2
Interleukin 6 family signaling 0.4586894586894508 0.1467586009979906 0.8833225623990013 1.0 1.0 3 P40763,P42224 2
Suppression of apoptosis 0.3718720304086194 0.1464326710909705 0.883579837476224 1.0 1.0 5 P27361,P28482,P49840,P23246 4
Mapk targets nuclear events mediated by map kinases 0.3284962084659197 0.1429091485462549 0.8863619332439323 1.0 1.0 8 P30154,P30153 2
Erk mapk targets 0.3284962084659197 0.1429091485462549 0.8863619332439323 1.0 1.0 8 P30154,P30153 2
Post chaperonin tubulin folding pathway 0.3280067994942348 0.1411173093151844 0.887777269632676 1.0 1.0 8 Q9BUF5,Q99426 2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4552073440962292 0.1403354584267822 0.8883949497459591 1.0 1.0 3 P24941,P11802 2
Rnd1 gtpase cycle 0.2940650407812148 0.1385432373737131 0.889811100582675 1.0 1.0 16 Q8TAA9,P38159,P51648,O75976 4
Diseases associated with n glycosylation of proteins 0.4532038135870924 0.1367118253076117 0.8912585820565602 1.0 1.0 3 O75340 1
Apc c mediated degradation of cell cycle proteins 0.4104505191289325 0.1340163559946497 0.8933896408939339 1.0 1.0 56 P06493,P49721,P61289,P60900,P20618,Q9UJX3,P62195,P28070,Q16763,P28072,P51665,O00231,Q99436,P28074,Q9UL46,Q96DE5,P63208 17
Translocation of slc2a4 glut4 to the plasma membrane 0.3380780114442685 0.1328065026613515 0.8943464115384314 1.0 1.0 30 Q12846,Q9Y3B8,Q9UIQ6 3
Oncogene induced senescence 0.3567807351077123 0.1303156954278225 0.8963166628029238 1.0 1.0 6 P27361,P28482,P11802,Q00534,Q9HCE1 5
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5943037974683525 0.1247725838474818 0.9007035926648168 1.0 1.0 2 P61088 1
Activated tak1 mediates p38 mapk activation 0.5943037974683525 0.1247725838474818 0.9007035926648168 1.0 1.0 2 P61088 1
Enos activation 0.4463437796771047 0.124704085101776 0.9007578232068214 1.0 1.0 3 P07900,P35270 2
Carboxyterminal post translational modifications of tubulin 0.3706392737767255 0.1246698104003003 0.900784958704429 1.0 1.0 4 Q9BUF5,Q13885 2
G protein beta gamma signalling 0.3704876504116572 0.1243433807720995 0.9010434009088713 1.0 1.0 4 Q13153,P60953,Q9UBI6 3
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.3545234244463529 0.1242154050282472 0.9011447252538304 1.0 1.0 6 P30154 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.3608262902055702 0.1190758348528158 0.9052152755047324 1.0 1.0 5 P10321 1
Autophagy 0.3855610294116385 0.1138736158263733 0.9093379810130492 1.0 1.0 48 Q8WUX9,P21796,Q13409,Q8IWA4,Q7Z3C6,Q9H9H4,P67870,Q9BUF5,P08670,Q8N4H5,Q9UK41,Q9NS69,Q9Y4P8,Q99816,Q15382,P50542,Q8NEB9,Q13885 18
Erks are inactivated 0.3502878097392782 0.1130319863694339 0.9100051962524884 1.0 1.0 6 P30154 1
Smad2 smad3 smad4 heterotrimer regulates transcription 0.3647878404053164 0.1123614555838053 0.9105368157320852 1.0 1.0 4 P50750,P28482,P27361 3
Rnd2 gtpase cycle 0.2945031955606012 0.1101216919804622 0.912312865067487 1.0 1.0 18 Q8TAA9,Q07065,P51648 3
Generation of second messenger molecules 0.4362139917695415 0.1081035394760399 0.9139135605147544 1.0 1.0 3 Q13153,Q8N8S7 2
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3293033475264571 0.1073979608908407 0.9144732721249168 1.0 1.0 29 Q13409,O75935,O60884,Q13561,Q9BUF5,Q02790,Q15185,Q14203,P31948,P54652 10
Defects in cobalamin b12 metabolism 0.3611587969025658 0.1050268802023495 0.9163544793552116 1.0 1.0 4 Q99707,O14678 2
Darpp 32 events 0.3163503449304881 0.1000895303454949 0.9202732471667792 1.0 1.0 8 P30154,P30153 2
Antigen processing cross presentation 0.3873508126134467 0.0984126583366849 0.9216046235741892 1.0 1.0 50 P49721,P61289,Q12846,P60900,P20618,P28070,P10321,P28072,O00231,Q9UIQ6,P28074,Q9UL46,Q03518 13
Synthesis of bile acids and bile salts 0.3437896070975857 0.0965504519133634 0.9230834062178316 1.0 1.0 6 P22059,O14734,Q9BXW6,P22307,P51659 5
Bile acid and bile salt metabolism 0.3437896070975857 0.0965504519133634 0.9230834062178316 1.0 1.0 6 P22059,O14734,Q9BXW6,P22307,P51659 5
Unfolded protein response upr 0.3667913128717966 0.0912213228735975 0.9273167323858252 1.0 1.0 43 O14773,Q92945,Q9NWM8,P43307,O43731 5
Raf activation 0.3136924446752796 0.0911902808977758 0.9273413974970848 1.0 1.0 8 P30154 1
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3134642309697429 0.0904342661700569 0.9279421277758118 1.0 1.0 8 Q96PU5 1
Biological oxidations 0.3548734082628052 0.0886839769536902 0.9293330668936856 1.0 1.0 39 P07099,P21964,Q16850,O43169,Q9NUJ1 5
Fcgr3a mediated il10 synthesis 0.3256126323400014 0.0828864158253697 0.9339418554720832 1.0 1.0 7 O43865 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3533789119602694 0.0823405645884533 0.9343758980431928 1.0 1.0 39 P49721,P61289,Q96J02,P60900,P20618,P28070,P28072,O00231,P28074,Q9UL46 10
Phase ii conjugation of compounds 0.3073491975465641 0.0809749690121714 0.9354618589547572 1.0 1.0 24 Q9NUJ1,P21964 2
Plasma lipoprotein clearance 0.277233193733172 0.079288411924157 0.9368032232283112 1.0 1.0 15 Q8WTV0,P09496,O15118,Q6PIU2,P01130 5
Interaction between l1 and ankyrins 0.4156378600822953 0.0784959337148752 0.9374335646697332 1.0 1.0 3 Q01082,Q13813 2
P75 ntr receptor mediated signalling 0.2826068451104562 0.0768027403469251 0.9387804706984866 1.0 1.0 14 Q92974,Q9NQC3,Q92542,P62258 4
Lipophagy 0.4124723013611864 0.0744218606054862 0.94067471478718 1.0 1.0 3 P11142,O60664 2
Ptk6 regulates cell cycle 0.5481012658227825 0.0723807359617512 0.9422989150542558 1.0 1.0 2 P24941 1
Aggrephagy 0.2864255218297664 0.0702914962130374 0.9439616508057171 1.0 1.0 13 P08670 1
Negative regulation of the pi3k akt network 0.2731763919546965 0.0626712988171533 0.9500282526770174 1.0 1.0 15 P30154,Q8TBX8,P30153 3
Binding and uptake of ligands by scavenger receptors 0.3133768723737397 0.0504329866039057 0.959777350314549 1.0 1.0 7 Q8WTV0 1
Regulation of commissural axon pathfinding by slit and robo 0.519936708860757 0.0501504528996616 0.9600024946902104 1.0 1.0 2 O94813 1
Fcgr activation 0.519936708860757 0.0501504528996616 0.9600024946902104 1.0 1.0 2 P07948 1
Platelet aggregation plug formation 0.3229725324470113 0.0493822467788108 0.9606146759175018 1.0 1.0 6 P62993 1
Integrin signaling 0.3229725324470113 0.0493822467788108 0.9606146759175018 1.0 1.0 6 P62993 1
Rab gefs exchange gtp for gdp on rabs 0.2991741991875242 0.0480011178321576 0.9617153517343592 1.0 1.0 24 P31150,P62258,Q15042,Q9H0U4,Q13637,P20339,P50395,P61026,P61106,P62820,P61020,Q7Z392,P20340,Q15286 14
G2 phase 0.511075949367086 0.0444949992386274 0.964509838060532 1.0 1.0 2 P24941 1
Rho gtpases activate ktn1 0.2982008085910697 0.0428556007983049 0.9658166416395868 1.0 1.0 8 P33176,Q07866 2
Estrogen dependent nuclear events downstream of esr membrane signaling 0.3820829376384909 0.041518324232833 0.9668826848233842 1.0 1.0 3 P27361,P28482 2
Negative feedback regulation of mapk pathway 0.5041139240506305 0.0404619332360673 0.9677248550502078 1.0 1.0 2 P28482 1
Signaling by nodal 0.5041139240506305 0.0404619332360673 0.9677248550502078 1.0 1.0 2 P28482 1
Signaling by activin 0.5041139240506305 0.0404619332360673 0.9677248550502078 1.0 1.0 2 P28482 1
Activation of the ap 1 family of transcription factors 0.5041139240506305 0.0404619332360673 0.9677248550502078 1.0 1.0 2 P28482 1
Non integrin membrane ecm interactions 0.3184019414152068 0.0401887956220282 0.967942610213104 1.0 1.0 6 O14936,P11047 2
Unwinding of dna 0.2902075179301333 0.0379551451057894 0.969723445257202 1.0 1.0 10 Q14566 1
Apoptotic cleavage of cell adhesion proteins 0.3069349275088081 0.034721743361575 0.9723016226842331 1.0 1.0 7 Q16625 1
Bicarbonate transporters 0.4911392405063265 0.0338459000632782 0.9730000339372248 1.0 1.0 2 Q9Y6M7 1
Cell extracellular matrix interactions 0.3057291719075879 0.0318874840643269 0.9745617798349916 1.0 1.0 7 Q15404,Q13418 2
Signaling by pdgf 0.2907975674168172 0.0297864777126639 0.9762373432048292 1.0 1.0 9 P51692 1
Downstream signal transduction 0.2907975674168172 0.0297864777126639 0.9762373432048292 1.0 1.0 9 P51692 1
Synthesis of pips at the er membrane 0.4806962025316428 0.0293065602737165 0.9766200948092256 1.0 1.0 2 Q9NTJ5 1
Synthesis of diphthamide eef2 0.3596074707185794 0.0238492769330891 0.9809728339031968 1.0 1.0 3 Q9H2P9,P13639 2
Interleukin 37 signaling 0.4585443037974656 0.0217055680841298 0.9826828221314272 1.0 1.0 2 P40763 1
Mapk1 erk2 activation 0.4585443037974656 0.0217055680841298 0.9826828221314272 1.0 1.0 2 P28482 1
Runx3 regulates notch signaling 0.4481012658227818 0.018949744123788 0.9848811965801276 1.0 1.0 2 Q06330 1
Notch4 intracellular domain regulates transcription 0.4481012658227818 0.018949744123788 0.9848811965801276 1.0 1.0 2 Q06330 1
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.4481012658227818 0.018949744123788 0.9848811965801276 1.0 1.0 2 Q06330 1
Ub specific processing proteases 0.4092256159148387 0.0176062875963343 0.9859529406786778 1.0 1.0 67 P21796,P49721,Q93009,P61289,P60900,P20618,P28070,P28072,Q9Y277,O00231,P45880,P28074,Q9UL46,Q96K76 14
Maturation of sars cov 1 nucleoprotein 0.4174050632911363 0.0132555137472782 0.989423939953973 1.0 1.0 2 P49841 1
Akt phosphorylates targets in the cytosol 0.4174050632911363 0.0132555137472782 0.989423939953973 1.0 1.0 2 P49841 1
Smooth muscle contraction 0.2783998966144512 0.0132409892985007 0.9894355277704374 1.0 1.0 11 P67936,P18206,P06753,Q13153,P60660 5
Apoptotic cleavage of cellular proteins 0.2763660686125841 0.011739487274451 0.9906334594949744 1.0 1.0 20 Q9UDY2,Q13813,Q9UJU6,P08670,P49354,Q16625,P55210,P20700 8
Tgf beta receptor signaling activates smads 0.2840379021596654 0.0107989637275108 0.991383841035463 1.0 1.0 9 Q96PU5 1
Condensation of prometaphase chromosomes 0.2804358296534791 0.0091462702531268 0.992702433921656 1.0 1.0 10 P06493,Q15003,O95067 3
Serine biosynthesis 0.2898734177215155 0.0077134935310201 0.9938455836310328 1.0 1.0 2 O43175 1
Signaling by notch 0.390200492325065 0.0071491081163098 0.9942958855998344 1.0 1.0 60 P67809,P49721,P61289,Q96J02,P60900,P20618,P28070,P28072,O00231,Q11206,P28074,Q9UBV2,Q9UL46,P63208,Q9HCE1,Q15363 16
Gap junction assembly 0.3255545829592627 0.0060339400324644 0.9951856416211776 1.0 1.0 3 Q9BUF5 1
Transport of connexons to the plasma membrane 0.3255545829592627 0.0060339400324644 0.9951856416211776 1.0 1.0 3 Q9BUF5 1
Signaling by erbb2 0.2793077393255587 0.0060012920009787 0.995211690509798 1.0 1.0 10 Q16543 1
Lysosome vesicle biogenesis 0.2669867999880367 0.003343326703917 0.99733241621086 1.0 1.0 13 Q9BXS5,P05067,P09496 3
Copi independent golgi to er retrograde traffic 0.2931690194689118 0.0024962455715326 0.9980082862669768 1.0 1.0 26 Q13409,Q10472,O75935,Q13561,Q15042,Q9BUF5,Q14203,Q8TD16,P20340 9