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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:4f17751a746cdc0079ff605da00dca4314ee05000852ff5a40afa9ef240f8401
+size 78020

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3021,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.5789473684210527
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C251/C251_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.6632152725871646	0.6577956269087238	0.5106694648111709	1.0	0.6615490794144715	4	P06576,P21281	2
+ATP:guanido phosphotransferase active site [IPR022415]	0.6472341835044804	0.6184343059369871	0.536289089740213	1.0	0.6792995136709366	2	P12532	1
+Malate dehydrogenase, active site [IPR001252]	0.619410400794975	0.5213268505997414	0.6021390993295139	1.0	0.7302538013145169	2	P40925	1
+Protein-tyrosine phosphatase, active site [IPR016130]	0.4331398318017068	0.4421266342299688	0.658397572006892	1.0	0.7626404253387735	7	Q8WUK0,O75319	2
+Thiolase, acyl-enzyme intermediate active site [IPR020615]	0.396051292571304	0.1144792257279697	0.9088579135909276	1.0	0.9774509636732618	5	P55084,P24752,P22307	3

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CASP7", "CDC34", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K4", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME6", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKG1", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRC", "SRPK1", "SUCLG1", "TALDO1", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "WNK2"], "leading_proteins": ["ACAT1", "ATP5B", "ATP6V1B2", "CKMT1A*", "DUSP11", "HADHB", "MDH1", "PTPMT1", "SCP2"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c240d8f353f9e0f51cfcdbec4f2effa07139659d7af47e8203c583edc26509c7
+size 70357

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3021,
+    "annotations_size": 30,
+    "title": "Average number of proteins per term",
+    "value": 4.733333333333333
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C251/C251_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4342650759069399	1.6925026867053616	0.090550168278976	0.9420087582937452	0.2091042432415495	34	Q9Y680,P31949,P80303,Q9NWM8,O75340	5
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.6363034117257462	0.5796012571732293	0.5621835450541806	0.9999999999826714	0.6983899665233042	2	O75600	1
+Peptidase M16, zinc-binding site [IPR001431]	0.5184318277339521	0.4247920967362243	0.6709882395338465	0.9999999999999968	0.725631359799746	5	O75439,P22695	2
+Beta tubulin, autoregulation binding site [IPR013838]	0.4273674881232965	0.4201322919120197	0.674388813786887	0.9999999999999976	0.725631359799746	7	Q9BVA1	1
+Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]	0.5869493209672187	0.416210556355904	0.6772559358130963	0.999999999999998	0.725631359799746	2	P50579	1
+2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]	0.564249671886898	0.3505998418618422	0.725888575191145	1.0	0.7509192157149776	4	P36957,O00330	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "CLK2", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EHD1", "EIF2AK2", "EPHA7", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K4", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PRKG1", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["DLST", "FKBP14", "FKBP7", "GCAT", "METAP2", "NUCB2", "PDCD6", "PDHX", "PMPCB", "S100A11", "TUBB2B", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ATPase, AAA-type, conserved site [IPR003960]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:d49fb3638e8075b85a62b7e91432b1cff4ae76f84ff6a9814def2c5bb27ca5e2
+size 102138

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3021,
+    "annotations_size": 270,
+    "title": "Average number of proteins per term",
+    "value": 2.6555555555555554
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C251/C251_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9672076846637973	1.9055282059943244	0.056711444561327	0.9999998574285252	0.1814531926150069	2	P30519	1
+Thioredoxin, conserved site [IPR017937]	0.5839942585954744	1.7671575952671286	0.0772018390957196	0.999999999620847	0.2148917170705598	13	Q9H1E5,Q9H3N1	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.9062603511096424	1.655966896324189	0.0977285228749518	0.9999999999991268	0.2430245716978025	2	O43175	1
+Adenylate kinase, conserved site [IPR033690]	0.7870695232076061	1.4636766468757605	0.143282319210938	1.0	0.308017573605946	5	P27144,Q9UIJ7	2
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.8449817820470393	1.4029980641655484	0.1606174162084257	1.0	0.318872811590257	2	P25325	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.9055666003976182	1.3241260523167098	0.1854611845663685	1.0	0.3429761632391746	3	Q08257,Q8N4Q0	2
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.8600832216860108	1.1586765880988106	0.246588037337974	1.0	0.3933077374680148	3	O60568	1
+Chromo domain, conserved site [IPR023779]	0.7105163528166445	1.1525505734713306	0.2490949003964093	1.0	0.3933077374680148	5	P83916,Q13185,P45973	3
+Fumarate lyase, conserved site [IPR020557]	0.7731036767141491	1.107466514934948	0.2680922818754361	1.0	0.4160052649791249	2	P07954	1
+Aldo/keto reductase, conserved site [IPR018170]	0.7661477310367729	1.0791700313050971	0.2805119366965094	1.0	0.4248054201201982	2	P14550	1
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.7509108976482325	1.0175041286662911	0.3089136692035088	1.0	0.4508469766753912	2	P52907	1
+Guanylate kinase, conserved site [IPR020590]	0.5718928842033255	0.917977735277187	0.358630522317557	1.0	0.4940318419680631	6	O14936,Q5T2T1	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.7164712229619127	0.8450186823421273	0.3981004082005954	1.0	0.5456198488028465	4	O43175	1
+Ribosomal S11, conserved site [IPR018102]	0.6975819807883474	0.8065639199609523	0.4199177676809675	1.0	0.572615137746774	2	P82912	1
+AMP-binding, conserved site [IPR020845]	0.4707787528537492	0.6979104447506795	0.485233202015324	1.0	0.623871259733988	8	O95573,Q6P1M0,Q96CM8,O60488	4
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.6575024842663217	0.6556428818299854	0.5120539276972877	1.0	0.64304446734078	2	P30046	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6901921802518374	0.573356775410381	0.5664031507651284	1.0	0.6951311395753849	3	P26583,P09429	2
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.6313348790990486	0.5622334612784858	0.5739569661432538	1.0	0.7012143930256947	2	P63167	1
+14-3-3 protein, conserved site [IPR023409]	0.5556649182530633	0.5515793028133877	0.5812366199536929	1.0	0.7052312359846755	5	P31946,P63104,Q04917	3
+Tubulin, conserved site [IPR017975]	0.4273674881232965	0.4201322919120197	0.674388813786887	1.0	0.7882466654651926	7	Q9BVA1	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.3116684910851965	0.2521200645468872	0.8009482615401602	1.0	0.9010667942326802	12	Q53GQ0,Q8NBN7	2
+Thiolase, conserved site [IPR020613]	0.3871418808435592	0.2226347233604102	0.8238198092946583	1.0	0.911603887334253	6	P55084,P24752,P22307	3
+Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]	0.4922159655515198	0.176942974663483	0.8595531822640021	1.0	0.9438310486404758	2	P11586	1
+Hexapeptide transferase, conserved site [IPR018357]	0.4471679364027988	0.1049515946005788	0.9164142184214426	1.0	0.9772162389275896	2	Q9Y5P6	1
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.4375621066578445	0.0931186236471062	0.9258093221885246	1.0	0.9791251168027753	2	P00491	1
+ATPase, AAA-type, conserved site [IPR003960]	0.2472633103644565	0.0830992385842171	0.9337726312756254	1.0	0.9791251168027753	19	Q9ULI0,Q9Y276,P62191,P62333,P43686,Q9Y4W6,Q96TA2,Q8NBU5	8
+Ribosomal protein L30, conserved site [IPR018038]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9978394072446328	2	Q6DKI1	1
+Malic enzyme, conserved site [IPR015884]	0.3448161642928243	0.0303577665423035	0.9757817267350744	1.0	0.9984757969162598	2	P23368	1
+Ribosomal protein L3, conserved site [IPR019926]	0.3345478635309813	0.0276530133604529	0.9779388992632334	1.0	0.9984757969162598	2	P39023	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.3690683409448957	0.0215996375332731	0.9827673226716976	1.0	0.9984757969162598	3	Q96CW1	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]	0.2280482146696141	0.0162469301870094	0.9870373955199524	1.0	0.9984757969162598	12	Q13356,Q9H2H8,O43447	3
+Phosphofructokinase, conserved site [IPR015912]	0.3442677269715005	0.0158154515868368	0.987381621394968	1.0	0.9984757969162598	3	P17858,P08237	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP3M1", "AP3S1", "APEX1", "APP", "ARIH2", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF7", "DCP2", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E2", "ENO1", "EP300", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGF1R", "ILVBL", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18B", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRKG1", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS21", "RPS24", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A3", "SLC27A4", "SLC37A4", "SLC4A2", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STX12", "STX18", "STX3", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACAT1", "ACSF2", "ACSL3", "ACSL4", "AFG3L2", "AK3", "AK4", "AKR1A1", "AP2M1", "ATAD1", "ATAD2B", "BCS1L", "CAPZA1", "CASK", "CBX1", "CBX3", "CBX5", "CRYZ", "DDT", "DYNLL1", "FH", "GMPPB", "HADHB", "HMGB1", "HMGB2", "HMOX2", "HSD17B12", "ME2", "MPP7", "MPST", "MRPS11", "MTHFD1", "PFKL", "PFKM", "PHGDH", "PLOD3", "PNP", "PPIH", "PPIL2", "PPIL3", "PSMC1", "PSMC4", "PSMC6", "RDH13", "RPL3", "RPL7L1", "SCP2", "SLC27A4", "TMX1", "TMX4", "TUBB2B", "YME1L1", "YWHAB", "YWHAH", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "RNA recognition motif domain [IPR000504]", "2": "Chromo/chromo shadow domain [IPR000953]", "3": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "4": "AAA ATPase, AAA+ lid domain [IPR041569]", "5": "Glutathione S-transferase, C-terminal [IPR004046]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:d2a99b93978e6b42a7cac47078f5a1b1f7de5c31215dcecdc1f31b2344799679
+size 447150

interpro_domain/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3021,
+    "annotations_size": 2546,
+    "title": "Average number of proteins per term",
+    "value": 2.1661429693637078
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C251/C251_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,197 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Actin-depolymerising factor homology domain [IPR002108]	0.7332799197053276	1.941966129237077	0.0521412008066257	1.0	0.1367779272169471	8	Q9Y281,Q6IBS0	2
+Ovarian carcinoma immunoreactive antigen domain [IPR009764]	0.965220271613118	1.897441196696257	0.0577697327898603	1.0	0.1437690192910399	2	Q56VL3	1
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.953958264325937	1.8515427554307864	0.0640915097392913	1.0	0.1549638972423891	2	P82663	1
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7650437164986097	1.7653965497447377	0.0774971428586206	1.0	0.1779149916303409	6	O43169,O15173,O95864	3
+Immunoglobulin V-set domain [IPR013106]	0.9306707508505476	1.6439585240893488	0.1001847699753684	1.0	0.2152493032550953	4	Q9BY67	1
+Reticulon [IPR003388]	0.9893969516235932	1.6296893253584863	0.1031671745876599	1.0	0.2205404084804215	3	O95197,Q16799	2
+NIPSNAP [IPR012577]	0.9476474486414872	1.477673297020509	0.1394952450619431	1.0	0.2753138712617884	3	Q9UFN0,O75323	2
+CD80-like, immunoglobulin C2-set [IPR013162]	0.940243797444272	1.450663612044635	0.146873552631471	1.0	0.2845814802128807	3	Q9BY67	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8545876117919863	1.4426937599083325	0.1491067578463862	1.0	0.2867264391819482	2	P98179	1
+L27 domain [IPR004172]	0.6896561422685162	1.436341256762228	0.1509052597691753	1.0	0.2888608880598687	6	O14936,Q5T2T1	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.6242891526691183	1.4284013607051722	0.1531763677528332	1.0	0.2910678926675804	8	P13674,O60568,Q6PK18	3
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.6242891526691183	1.4284013607051722	0.1531763677528332	1.0	0.2910678926675804	8	P13674,O60568,Q6PK18	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.921382991015786	1.381833385284401	0.1670228656007242	1.0	0.3091347024171393	3	Q96G23	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.6762458086415295	1.3772221668145144	0.1684435704728615	1.0	0.3108064913913558	6	P05023,P16615	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7639164371701652	1.36962297186558	0.1708046249151187	1.0	0.3135317772414508	5	Q92604,O15228,Q86UL3	3
+Band 7 domain [IPR001107]	0.6392715118449288	1.3526232896913633	0.1761760082187708	1.0	0.3187365475285256	7	O94905,O75477,Q99623,Q14254	4
+Glycosyl transferase, family 1 [IPR001296]	0.8513461316937146	1.3461259631099736	0.1782618968095137	1.0	0.321654705369966	4	Q9BT22	1
+Immunoglobulin-like domain [IPR007110]	0.5354723611765801	1.3402963236188132	0.1801490262499432	1.0	0.3243701703199119	11	Q9BY67,P15151	2
+CARG-binding factor, N-terminal [IPR012956]	0.8284200066247118	1.334597380236218	0.1820081559221762	1.0	0.3251879052476215	2	Q99729	1
+Immunoglobulin subtype [IPR003599]	0.5550921133983158	1.3331789979603288	0.1824730697728256	1.0	0.3257415248158207	10	Q9BY67,P15151	2
+Uncharacterised domain CHP00451 [IPR004521]	0.8204703544219959	1.3018009244055613	0.1929844477272906	1.0	0.3381544417850529	2	Q9ULC4	1
+EF-hand domain [IPR002048]	0.3738194541643952	1.2714692496136424	0.2035617603197603	1.0	0.3508925130494989	40	Q9Y680,P31949,P80303,Q9NWM8,O75340	5
+Exosome complex component, N-terminal domain [IPR025721]	0.8098708181517095	1.2581287459065091	0.2083451988274451	1.0	0.3537954337771332	2	Q9Y3B2	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8276741928770364	1.2570474518970152	0.2087364534365621	1.0	0.3537954337771332	4	P05023,P16615	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8276741928770364	1.2570474518970152	0.2087364534365621	1.0	0.3537954337771332	4	P05023,P16615	2
+Aminotransferase, class I/classII [IPR004839]	0.615393203948166	1.242567123185774	0.2140273912848842	1.0	0.3584958804021811	7	P00505,Q8TD30	2
+Adenylate kinase, active site lid domain [IPR007862]	0.8820410868124656	1.238413466497262	0.2155627898900061	1.0	0.3603564432435689	3	P27144,Q9UIJ7	2
+L27 domain, C-terminal [IPR014775]	0.7303908832273012	1.2332648729600122	0.2174769588803546	1.0	0.3630795654487757	5	O14936,Q5T2T1	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.7999337528983179	1.2172632740923166	0.2235040628001323	1.0	0.3707109732176787	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.7999337528983179	1.2172632740923166	0.2235040628001323	1.0	0.3707109732176787	2	Q9Y282	1
+LEM domain [IPR003887]	0.7229312326765722	1.2029476970924862	0.228996561092412	1.0	0.37711852816383	5	Q86XL3,P50402,P42167	3
+RNA recognition motif domain [IPR000504]	0.3221884239363743	1.1984008025065194	0.2307610202057979	1.0	0.3790435854477171	117	Q14103,P18615,Q9UKA9,Q9NW64,P08579,P98179,P55795,Q01844,A0AV96,P42696,Q9Y3B4,P38159,Q9BWF3,Q93062,P43243,Q9UKM9,Q8IZ69,O14979,Q07955,Q13148,Q12849,P35637,Q14011,Q9BY77,P22626,P31483,Q8IY67,Q13595,Q01085,Q8WUA2,Q8N684,Q96EP5,Q86U42,Q9GZT3,O95319,P09651,P33240,P62995,Q13151,P52272,P09012,Q13242,P23246,Q9BYG3,P26368,Q99729,Q13283,P51991,P31943,Q92804,O43251,Q15427,P23588,Q8WXF1	54
+Pumilio homology domain [IPR033133]	0.7919841006955974	1.1846386185879758	0.2361603610710994	1.0	0.3841944276594371	2	Q14671	1
+LEM-like domain [IPR013146]	0.790990394170261	1.1805653800742677	0.2377754234249502	1.0	0.3860817780866858	2	P42167	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.8600832216860108	1.1586765880988106	0.246588037337974	1.0	0.3963466812263144	3	O60568	1
+NADP-dependent oxidoreductase domain [IPR023210]	0.7984838092243223	1.1474844975282843	0.2511814365921632	1.0	0.4009454154004059	4	P48507,P14550	2
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5399087849888905	1.131100640083774	0.2580127349331373	1.0	0.4057445479553846	9	Q9NWM8,O00170,Q9Y680	3
+Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]	0.7780722093408449	1.1277264190535916	0.2594354766684215	1.0	0.4069764162648189	2	Q96HY7	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.7744286187479335	1.112865410149382	0.2657662377133092	1.0	0.414100882018412	2	P32322	1
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.7744286187479335	1.112865410149382	0.2657662377133092	1.0	0.414100882018412	2	P32322	1
+Fumarate lyase, N-terminal [IPR022761]	0.7731036767141491	1.107466514934948	0.2680922818754361	1.0	0.416001566153436	2	P07954	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.5574516865541885	1.1068371463233728	0.2683643447445518	1.0	0.416111828087472	8	O00303,O00487	2
+Peptidase M20, dimerisation domain [IPR011650]	0.7704537926465754	1.0966772474915711	0.2727825059440532	1.0	0.420656729335893	2	Q96KP4	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.7654852600198798	1.0764795120846604	0.2817128589072917	1.0	0.4275175407010058	2	Q8IWA4	1
+Peptidase M41 [IPR000642]	0.7608479629016277	1.0576686148798922	0.2902065486395146	1.0	0.433861346351265	2	Q96TA2	1
+Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]	0.7568731368002695	1.0415781661571066	0.2976072957976323	1.0	0.4395059020306102	2	P13804	1
+Legume-like lectin [IPR005052]	0.7558794302749308	1.0375605685471612	0.2994746836452324	1.0	0.4412398984726631	2	P49257	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.7555481947664833	1.036221826530974	0.3000986663387963	1.0	0.4413929546496681	2	O75431	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.7555481947664833	1.036221826530974	0.3000986663387963	1.0	0.4413929546496681	2	O75431	1
+MPN domain [IPR037518]	0.5101744762382253	0.9817090808276516	0.3262431904360543	1.0	0.4669000353289456	9	O00303,O00487	2
+PUA domain [IPR002478]	0.7515461981320117	0.9729608649288922	0.3305727527822686	1.0	0.4717703075020492	4	Q9Y221,Q9ULC4	2
+NECAP, PHear domain [IPR012466]	0.7353428287512473	0.95503682140606	0.3395590765574008	1.0	0.4800591333283864	2	Q9NVZ3	1
+Rhodanese-like domain [IPR001763]	0.656771857108604	0.9362247385587814	0.3491574885699664	1.0	0.4892898109301731	5	P25325,Q16762	2
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.7300430606161035	0.9339170151838236	0.3503467010822461	1.0	0.4901003851403288	2	Q9NWU2	1
+CRA domain [IPR013144]	0.7300430606161035	0.9339170151838236	0.3503467010822461	1.0	0.4901003851403288	2	Q9NWU2	1
+Cold-shock protein, DNA-binding [IPR002059]	0.6519969618709821	0.9172388232564272	0.3590175069677992	1.0	0.4983961683424301	5	P16989	1
+Cold shock domain [IPR011129]	0.6519969618709821	0.9172388232564272	0.3590175069677992	1.0	0.4983961683424301	5	P16989	1
+Chromo shadow domain [IPR008251]	0.7889330682571285	0.904175092884882	0.3659025650541778	1.0	0.5051995285400959	3	P83916,Q13185	2
+Chromo domain subgroup [IPR017984]	0.7889330682571285	0.904175092884882	0.3659025650541778	1.0	0.5051995285400959	3	P83916,Q13185	2
+Immunoglobulin subtype 2 [IPR003598]	0.4914471637484061	0.8884590790725115	0.3742938582596515	1.0	0.5134440534100608	9	Q13308,P35613,Q9BY67	3
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.7164712229619127	0.8450186823421273	0.3981004082005954	1.0	0.5345799785225296	4	O43175	1
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.7164712229619127	0.8450186823421273	0.3981004082005954	1.0	0.5345799785225296	4	O43175	1
+SMARCC, SWIRM-associated domain [IPR032448]	0.7052003974826164	0.8361065252016655	0.4030949778206625	1.0	0.5376801949379818	2	Q8TAQ2	1
+SMARCC, C-terminal [IPR032451]	0.7052003974826164	0.8361065252016655	0.4030949778206625	1.0	0.5376801949379818	2	Q8TAQ2	1
+SMARCC, N-terminal [IPR032450]	0.7052003974826164	0.8361065252016655	0.4030949778206625	1.0	0.5376801949379818	2	Q8TAQ2	1
+Dynamin, N-terminal [IPR045063]	0.54936710098099	0.820954178381563	0.4116723689369708	1.0	0.5413831876619462	6	Q9H4M9	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.54936710098099	0.820954178381563	0.4116723689369708	1.0	0.5413831876619462	6	Q9H4M9	1
+DNA/RNA non-specific endonuclease [IPR001604]	0.7008943358728122	0.8193796094692669	0.4125698648385913	1.0	0.5417240205668147	2	Q9Y2C4	1
+Extracellular Endonuclease, subunit A [IPR020821]	0.7008943358728122	0.8193796094692669	0.4125698648385913	1.0	0.5417240205668147	2	Q9Y2C4	1
+FAD dependent oxidoreductase [IPR006076]	0.7032953338436525	0.7977704482147471	0.4250037134401183	1.0	0.5540498998558839	4	Q8NCN5,Q9H9P8	2
+Peptidase M16, N-terminal [IPR011765]	0.5167506615299795	0.7926129287264018	0.4280033738145761	1.0	0.5562514495823945	7	O75439,Q5JRX3,P22695	3
+Peptidase M16, C-terminal [IPR007863]	0.5167506615299795	0.7926129287264018	0.4280033738145761	1.0	0.5562514495823945	7	O75439,Q5JRX3,P22695	3
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.6929446836700963	0.7886999353410421	0.4302874057278716	1.0	0.5570223729176585	2	P49591	1
+Transketolase, C-terminal domain [IPR033248]	0.6886386220602918	0.772196864413651	0.4399978383866627	1.0	0.56321493038333	2	P29401	1
+Transketolase-like, pyrimidine-binding domain [IPR005475]	0.6890951276102042	0.7474727706266232	0.4547782332693006	1.0	0.5689462202810046	4	Q02218,P29401,Q96HY7	3
+Cold-shock (CSD) domain [IPR019844]	0.6874322977590381	0.741629658749002	0.4583117487717727	1.0	0.56920083530387	4	P16989	1
+Zinc finger, CHHC-type [IPR012996]	0.7370653562766745	0.7257259701204911	0.4680067778240706	1.0	0.5734937242270893	3	P31943	1
+Major facilitator superfamily domain [IPR020846]	0.7369888173178973	0.72546924707397	0.4681642046204115	1.0	0.5734937242270893	3	Q14728	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.669095727061949	0.6984273505929381	0.4849099767579394	1.0	0.5873518206801499	2	Q86UL3	1
+AMP-dependent synthetase/ligase [IPR000873]	0.4707787528537492	0.6979104447506795	0.485233202015324	1.0	0.587448279757972	8	O95573,Q6P1M0,Q96CM8,O60488	4
+Tim44-like domain [IPR007379]	0.6598211328254471	0.6641363953752638	0.5066030178307979	1.0	0.6064472611622892	2	Q9BRJ2	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.6632152725871646	0.6577956269087238	0.5106694648111709	1.0	0.6092616951308534	4	P06576,P21281	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.6632152725871646	0.6577956269087238	0.5106694648111709	1.0	0.6092616951308534	4	P06576,P21281	2
+Dehydrogenase, E1 component [IPR001017]	0.7133863485752175	0.6474606358636555	0.517333863165617	1.0	0.6166348387732495	3	Q02218,Q96HY7	2
+KOW [IPR005824]	0.5060916622986286	0.6401340281648783	0.5220854681255584	1.0	0.6220073008178155	6	P61353,P62701,Q96A35	3
+ATP:guanido phosphotransferase, catalytic domain [IPR022414]	0.6472341835044804	0.6184343059369871	0.536289089740213	1.0	0.6350660569667825	2	P12532	1
+ATP:guanido phosphotransferase, N-terminal [IPR022413]	0.6472341835044804	0.6184343059369871	0.536289089740213	1.0	0.6350660569667825	2	P12532	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7023413219488452	0.6118275826890549	0.5406518383855323	1.0	0.6384506403198354	3	O75396	1
+Longin domain [IPR010908]	0.7023413219488452	0.6118275826890549	0.5406518383855323	1.0	0.6384506403198354	3	O75396	1
+Thioredoxin domain [IPR013766]	0.3334155606849044	0.60470947127907	0.5453720538871889	1.0	0.6434278263191765	26	Q9H1E5,Q9H3N1	2
+Rpn11/EIF3F, C-terminal [IPR024969]	0.6450055117602072	0.5965393581215602	0.5508149690061508	1.0	0.6477621760831147	4	O00487	1
+Ulp1 protease family, C-terminal catalytic domain [IPR003653]	0.6406094733355505	0.5947991828635588	0.5519777138529316	1.0	0.6482173706040424	2	Q9H4L4	1
+SCP2 sterol-binding domain [IPR003033]	0.6914005630404387	0.5771473072094475	0.563839949127211	1.0	0.6588051906736482	3	P22307	1
+Thioesterase domain [IPR006683]	0.6323285856243881	0.5656922892074315	0.5716029778683169	1.0	0.6657370455867955	2	Q9NPJ3	1
+Zinc finger, RanBP2-type [IPR001876]	0.4637467667860502	0.5643830974324051	0.5724934395408989	1.0	0.6664692716374617	7	Q01844,Q92804	2
+14-3-3 domain [IPR023410]	0.5556649182530633	0.5515793028133877	0.5812366199536929	1.0	0.6747963677164168	5	P31946,P63104,Q04917	3
+Ribosomal protein S7 domain [IPR023798]	0.6270288174892443	0.5473323301127903	0.5841504363518357	1.0	0.6778701052651658	2	P46782	1
+Nuclear transport factor 2, eukaryote [IPR018222]	0.6281073914484518	0.5413112748081038	0.5882930504605057	1.0	0.681633361446076	4	Q9UN86,P61970,Q13283	3
+Nuclear transport factor 2 domain [IPR002075]	0.6281073914484518	0.5413112748081038	0.5882930504605057	1.0	0.681633361446076	4	Q9UN86,P61970,Q13283	3
+Proteasome component (PCI) domain [IPR000717]	0.3623727857988396	0.5351815732179659	0.5925243069754658	1.0	0.6857122207088799	16	Q9BT78	1
+Myb domain [IPR017930]	0.4148729311239656	0.5243560809287681	0.6000308975629236	1.0	0.6918245492317586	9	Q92922,Q15554,Q8TAQ2	3
+Sec23, C-terminal [IPR037550]	0.6144418681682775	0.5046234500315793	0.6138233361653729	1.0	0.7052320459733932	2	Q15436	1
+AP180 N-terminal homology (ANTH) domain [IPR011417]	0.6114607485922593	0.4947022734024923	0.6208102965411797	1.0	0.7108255360018253	2	Q13492	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.6122177447745418	0.4909983028215391	0.6234276479284677	1.0	0.7127286895491148	4	Q12931	1
+SWIB/MDM2 domain [IPR003121]	0.6084796290162406	0.4848586446212196	0.6277766196261501	1.0	0.7170566503221973	2	Q96GM5	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.6028486253726503	0.4664822180598545	0.6408703727924412	1.0	0.7287431751360229	2	Q9NVE7	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.5276237167785438	0.4550312562267565	0.6490867525040918	1.0	0.7374274305557419	5	Q6PK18	1
+F-BAR domain [IPR031160]	0.6470752967502282	0.4440047712129504	0.6570391343743378	1.0	0.7448003722693962	3	Q9UKS6	1
+FCH domain [IPR001060]	0.6470752967502282	0.4440047712129504	0.6570391343743378	1.0	0.7448003722693962	3	Q9UKS6	1
+Chromo/chromo shadow domain [IPR000953]	0.3963384807955109	0.4435010450807011	0.6574033634684568	1.0	0.7448816036451673	9	Q13185,P83916,Q9HC52,Q8TAQ2,P45973	5
+RNA-binding S4 domain [IPR002942]	0.6451292246521014	0.4384653782878842	0.6610489623300366	1.0	0.7480680783990576	3	Q9NV31,P62701	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.4273674881232965	0.4201322919120197	0.674388813786887	1.0	0.7587246663285082	7	Q9BVA1	1
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.4273674881232965	0.4201322919120197	0.674388813786887	1.0	0.7587246663285082	7	Q9BVA1	1
+Ribosomal protein L18e/L15P [IPR021131]	0.6355280710338115	0.4115566374657927	0.6806644201630245	1.0	0.7645545037443995	3	Q9P015	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.6352219520093825	0.4107104449015535	0.6812848671588183	1.0	0.7647933297117951	3	Q9NRG0	1
+GOLD domain [IPR009038]	0.5852047909102718	0.4096142686662748	0.6820889282733935	1.0	0.7653584889308329	4	Q9BVK6	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.4417001332915579	0.3945448382755925	0.6931788300655228	1.0	0.7757509016909104	6	Q6P1M0	1
+Disulphide isomerase [IPR005788]	0.5083276013406195	0.3924531837615053	0.6947233963420749	1.0	0.7768296197518334	5	P30101,P13667	2
+Aminoacyl-tRNA synthetase, class II [IPR006195]	0.3530654251680445	0.3804051969747661	0.7036446574568811	1.0	0.7826471375645344	11	Q9BW92,Q15046,P49591,Q9Y285	4
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]	0.33255616428437	0.3593887363705519	0.7193042997419941	1.0	0.796893545409239	14	Q9H2H8,O43447,Q8WUA2,Q96BP3,Q13356	5
+2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]	0.564249671886898	0.3505998418618422	0.725888575191145	1.0	0.8019620777818767	4	P36957,O00330	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5647565419013038	0.3503850815636227	0.7260497208512278	1.0	0.8019620777818767	2	Q92945	1
+ENTH  domain [IPR013809]	0.611663353214046	0.3478979187348887	0.7279168483670684	1.0	0.8033273931263788	3	Q13492,Q14677	2
+NOPS [IPR012975]	0.591782637508294	0.2986921312015607	0.7651749615226326	1.0	0.8375474858282987	3	P23246,Q8WXF1	2
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.5432458065476697	0.2955440796063398	0.7675782846279684	1.0	0.8397282353659837	4	Q9BW92	1
+Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]	0.5428949983438354	0.291024482484594	0.7710325951996557	1.0	0.8407062044446781	2	Q9UGN5	1
+WGR domain [IPR008893]	0.5428949983438354	0.291024482484594	0.7710325951996557	1.0	0.8407062044446781	2	Q9UGN5	1
+NOSIC [IPR012976]	0.583631785532226	0.2795984898921524	0.7797855658038113	1.0	0.8487960883011986	3	Q9Y2X3	1
+Nop domain [IPR002687]	0.583631785532226	0.2795984898921524	0.7797855658038113	1.0	0.8487960883011986	3	Q9Y2X3	1
+Tubulin binding cofactor C-like domain [IPR012945]	0.5322954620735476	0.2643587009897597	0.7915035316505472	1.0	0.8582487187318114	2	Q15814	1
+CTLH, C-terminal LisH motif [IPR006595]	0.576090262254024	0.262515905086938	0.79292372473892	1.0	0.859211313588717	3	Q9NWU2	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.3605546314203762	0.2528130402964539	0.8004126902797246	1.0	0.865611781780289	8	Q5T2T1	1
+Guanylate kinase-like domain [IPR008144]	0.3605546314203762	0.2528130402964539	0.8004126902797246	1.0	0.865611781780289	8	Q5T2T1	1
+Zinc finger, PARP-type [IPR001510]	0.5223583968201528	0.240675457009717	0.8098066623656808	1.0	0.8728906699335408	2	P09874	1
+EF hand associated, type-2 [IPR013567]	0.5163961576681158	0.227091614609081	0.820352504303103	1.0	0.881645198799367	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.5163961576681158	0.227091614609081	0.820352504303103	1.0	0.881645198799367	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.5163961576681158	0.227091614609081	0.820352504303103	1.0	0.881645198799367	2	Q8IXI1	1
+Phox homology [IPR001683]	0.3260116236347981	0.2253516242135048	0.8217057419937945	1.0	0.8827269278971313	10	O00443	1
+Thiolase, N-terminal [IPR020616]	0.3871418808435592	0.2226347233604102	0.8238198092946583	1.0	0.883512374121856	6	P55084,P24752,P22307	3
+Thiolase, C-terminal [IPR020617]	0.3871418808435592	0.2226347233604102	0.8238198092946583	1.0	0.883512374121856	6	P55084,P24752,P22307	3
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.3478265287320407	0.2122711874901119	0.831895472276591	1.0	0.8909785375947902	8	Q8WUK0,O75319	2
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.5520212060967518	0.2118980750368202	0.8321865523960765	1.0	0.8909785375947902	3	Q99797,P52888	2
+Zinc finger, GATA-type [IPR000679]	0.4350132625994686	0.1920055893092522	0.8477378272506746	1.0	0.9061043275315774	5	O94776,Q86YP4,Q9BTC8,Q13330	4
+Peripheral subunit-binding domain [IPR004167]	0.5369070483386064	0.1832602923443363	0.8545937888399247	1.0	0.91207796685189	3	O00330	1
+CARP motif [IPR006599]	0.5324718356527454	0.175328702159125	0.8608213600029297	1.0	0.91547668444756	3	Q01518,Q15814	2
+C-CAP/cofactor C-like domain [IPR017901]	0.5324718356527454	0.175328702159125	0.8608213600029297	1.0	0.91547668444756	3	Q01518,Q15814	2
+ZU5 domain [IPR000906]	0.4845975488572497	0.1628099734667622	0.8706680553581869	1.0	0.9236859008832522	2	Q07157	1
+Methyl-CpG DNA binding [IPR001739]	0.4824152472912518	0.1627474730813683	0.8707172671326808	1.0	0.9236859008832522	4	P51608	1
+Chromo domain [IPR023780]	0.3453520953904235	0.1581163149170606	0.8743651448847185	1.0	0.9265081779937676	7	P83916,Q13185,P45973	3
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4048583648647913	0.1300924008532316	0.8964933222692291	1.0	0.9482642287068788	5	P43686,P62191,P62333	3
+Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]	0.46306724080823	0.1272023941765521	0.8987802104971594	1.0	0.9500020657010976	2	P47897	1
+ELM2 domain [IPR000949]	0.4411667219091705	0.0974433301063434	0.922374335981508	1.0	0.9694782021475464	4	Q9UKL0,Q13330,Q9BTC8	3
+AAA ATPase, AAA+ lid domain [IPR041569]	0.2601144443895864	0.0968704348947476	0.9228292878942548	1.0	0.9694782021475464	17	Q9ULI0,P62191,P62333,P43686,Q9Y4W6,Q96TA2,Q8NBU5	7
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.3321780960565452	0.0966272042764798	0.923022451691144	1.0	0.9694782021475464	6	Q15428,Q12874	2
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.3176552056132558	0.0958892061527949	0.9236085673182548	1.0	0.9695150847476628	7	O14818,P60900,P28066	3
+Nucleoside phosphorylase domain [IPR000845]	0.4375621066578445	0.0931186236471062	0.9258093221885246	1.0	0.9699861092007436	2	P00491	1
+Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]	0.4345809870818274	0.0896856577821316	0.928537013439994	1.0	0.9720621859449936	2	Q86YP4	1
+Glycosyl transferase CAP10 domain [IPR006598]	0.4703663642244305	0.0869111450156703	0.9307421406026912	1.0	0.9735700451826014	3	Q8NBL1	1
+Dual specificity protein phosphatase domain [IPR020422]	0.3755792186376963	0.0825096807340031	0.9342414204722432	1.0	0.9760273518762128	5	Q8WUK0	1
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.3755792186376963	0.0825096807340031	0.9342414204722432	1.0	0.9760273518762128	5	Q8WUK0	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.4166942696257134	0.0713708426341894	0.9431026146229096	1.0	0.9832675089393644	2	Q9Y6M7	1
+Band 3 cytoplasmic domain [IPR013769]	0.4166942696257134	0.0713708426341894	0.9431026146229096	1.0	0.9832675089393644	2	Q9Y6M7	1
+Ricin B, lectin domain [IPR000772]	0.4155754000821899	0.067025612281671	0.9465613133916058	1.0	0.9856626191799708	4	Q10472	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.4051010268300887	0.0614790746835575	0.9509776788611906	1.0	0.9885346927850382	2	Q15067	1
+Metastasis-associated protein MTA1, R1 domain [IPR035170]	0.4410205434062231	0.0591896869645298	0.9528010238519604	1.0	0.9893276536407386	3	Q13330,Q9BTC8	2
+Peptidase S9A, N-terminal domain [IPR023302]	0.4011262007287306	0.0584228353778837	0.9534118258343484	1.0	0.9895582994595398	2	Q4J6C6	1
+CID domain [IPR006569]	0.3075687395250658	0.0572797753914432	0.954322330797638	1.0	0.990099696092415	6	Q96P16,Q9NQG5	2
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.3981450811527094	0.0562383340752954	0.9551519432946995	1.0	0.9905567607447272	2	O95394	1
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.3517904509283815	0.0527449210684155	0.9579351469798044	1.0	0.9914239366709684	5	Q9Y295,Q9BZE4,A4D1E9,P55039	4
+Ribosomal protein L30, N-terminal [IPR012988]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9946601160321346	2	Q6DKI1	1
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9946601160321346	2	Q6DKI1	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9946601160321346	2	Q6DKI1	1
+Lamin tail domain [IPR001322]	0.4155069582504914	0.041494891729588	0.9669013651577854	1.0	0.9955941703720272	3	P02545,Q03252	2
+Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]	0.4118621603711014	0.0394020544133019	0.9685698419981232	1.0	0.9962158484057476	3	Q9UGN5,P09874	2
+Dbl homology (DH) domain [IPR000219]	0.3643590592911675	0.0372702906160587	0.9702694936817792	1.0	0.9962158484057476	2	Q9H8V3	1
+ATP-citrate lyase/succinyl-CoA ligase [IPR005811]	0.3722240636393705	0.0314184778011728	0.9749358052707788	1.0	0.9972625794372852	4	P53597,Q9P2R7,P53396	3
+Malic enzyme, NAD-binding [IPR012302]	0.3448161642928243	0.0303577665423035	0.9757817267350744	1.0	0.9973264858560816	2	P23368	1
+Malic enzyme, N-terminal domain [IPR012301]	0.3448161642928243	0.0303577665423035	0.9757817267350744	1.0	0.9973264858560816	2	P23368	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.2840712093793561	0.029168171998926	0.9767304654931748	1.0	0.9976133358563832	6	Q9UNK0,O15400	2
+Ubiquitin conjugation factor E4, core [IPR019474]	0.3309042729380697	0.0268246602776001	0.9785995842355788	1.0	0.9976133358563832	2	O95155	1
+3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]	0.3289168598873907	0.0263996160474716	0.9789386003940272	1.0	0.9976133358563832	2	P31937	1
+Zinc finger, LIM-type [IPR001781]	0.2728784883005875	0.0262440535506779	0.9790626783178764	1.0	0.9976133358563832	7	Q9UHB6,Q16527	2
+Methyltransferase type 11 [IPR013216]	0.36348575215374	0.0200580581743388	0.9839970581359958	1.0	0.998354797166588	3	Q6UX53,Q6FI81	2
+Copine, C2B domain [IPR037768]	0.3503974010008928	0.0199157821772293	0.9841105552853532	1.0	0.998354797166588	4	Q99829	1
+Copine, C-terminal [IPR010734]	0.3503974010008928	0.0199157821772293	0.9841105552853532	1.0	0.998354797166588	4	Q99829	1
+WH1/EVH1 domain [IPR000697]	0.2669758198078967	0.0197557305710191	0.9842382328704384	1.0	0.998354797166588	2	P50552	1
+VASP tetramerisation [IPR014885]	0.2669758198078967	0.0197557305710191	0.9842382328704384	1.0	0.998354797166588	2	P50552	1
+Mu homology domain [IPR028565]	0.344702427935431	0.0175027800991907	0.9860355149884408	1.0	0.9993815370862142	4	Q96CW1	1
+Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]	0.3427245608220056	0.0167165441343482	0.9866627486946976	1.0	0.9996193227921608	4	P62888,Q9NX24,P62424	3
+Phosphofructokinase domain [IPR000023]	0.3442677269715005	0.0158154515868368	0.987381621394968	1.0	0.9999497247699238	3	P17858,P08237	2
+6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]	0.3290258449304122	0.0134327533198951	0.9892825358257908	1.0	1.0	3	P31937,P52209	2
+Glutathione S-transferase, C-terminal [IPR004046]	0.2381268681501093	0.011723057953794	0.990646567294274	1.0	1.0	10	P21266,P78417,O43708,Q13155,P26641,P07814,O43324,P28161,P26640	9
+Replication factor C, C-terminal [IPR013748]	0.30583167660702	0.0110523587429225	0.9911816731321812	1.0	1.0	3	P40937,P35249	2
+Glycosyltransferase 2-like [IPR001173]	0.300629764666883	0.0052570236211458	0.9958055213368971	1.0	1.0	4	Q86SF2,O60762,Q10472	3
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.2900232018561456	0.0036231748680743	0.9971091310366064	1.0	1.0	4	P48147,Q4J6C6,Q86TI2	3
+SWIRM domain [IPR007526]	0.2889464450635991	0.0034785873804624	0.9972244944332598	1.0	1.0	4	Q8TAQ2	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:efc1f49715ad41ca5915988b1181c13f8bf52e2934539e87b8d7119c44b5651d
+size 529499

interpro_family/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3021,
+    "annotations_size": 2341,
+    "title": "Average number of proteins per term",
+    "value": 1.2785134557881248
+}

interpro_family/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C251/C251_val_log2fc"}

interpro_family/result.tsv

@@ -0,0 +1,110 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase [IPR002051]	0.9672076846637973	1.9055282059943244	0.056711444561327	1.0	0.1165596942213051	2	P30519	1
+Haem oxygenase-like [IPR016053]	0.9672076846637973	1.9055282059943244	0.056711444561327	1.0	0.1165596942213051	2	P30519	1
+OCIA domain-containing protein 1/2 [IPR040187]	0.965220271613118	1.897441196696257	0.0577697327898603	1.0	0.1178579347541904	2	Q56VL3	1
+Short-chain dehydrogenase/reductase SDR [IPR002347]	0.535527106276485	1.8756140610465544	0.0607082942045744	1.0	0.1219897997707371	19	Q53GQ0,Q96LJ7,Q9Y394,P35270,Q3SXM5,Q8NBN7	6
+Cleft lip and palate transmembrane 1 [IPR008429]	0.953627028817491	1.8501909944762376	0.0642860264683302	1.0	0.1271060709141563	2	Q96KA5	1
+Cleft lip and palate transmembrane protein 1-like protein [IPR030434]	0.953627028817491	1.8501909944762376	0.0642860264683302	1.0	0.1271060709141563	2	Q96KA5	1
+Nuclear pore protein POM121 [IPR026090]	0.950314673733026	1.8366678771992744	0.0662589401780029	1.0	0.1295332163823319	2	A8CG34	1
+Mitochondrial carrier UCP-like [IPR002030]	0.9436899635640956	1.8095922755493976	0.0703590386914991	1.0	0.1351193679875304	2	Q9H2D1	1
+Adenylate kinase 3/4, mitochondrial [IPR028586]	0.9324279562769144	1.7634783758533277	0.0778198412471984	1.0	0.1446991647018995	2	P27144	1
+Integral membrane protein EMC3/TMCO1-like [IPR002809]	0.9125538257701246	1.6818656545154933	0.092594893993581	1.0	0.1649654846567528	2	Q9P0I2	1
+Derlin [IPR007599]	0.9118913547532314	1.6791406040909729	0.0931246444397055	1.0	0.1655313535560749	2	Q9BUN8	1
+THRAP3/BCLAF1 family [IPR029199]	0.8936734017886738	1.6041035648800488	0.1086912262452377	1.0	0.1864474104065399	2	Q9NYF8	1
+Sulfotransferase [IPR005331]	0.8916859887379927	1.5959075402339338	0.1105094378206552	1.0	0.1882842750641586	2	Q8NCH0	1
+Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]	0.8678370321298491	1.4974454764514746	0.1342773827011465	1.0	0.2161588219124382	2	Q99595	1
+Adenylate kinase/UMP-CMP kinase [IPR000850]	0.7870695232076061	1.4636766468757605	0.143282319210938	1.0	0.2269444582359986	5	P27144,Q9UIJ7	2
+Nuclear pore complex protein [IPR026054]	0.8802415415337524	1.4548658169284283	0.1457064128011067	1.0	0.2296961026043036	4	A8CG34	1
+Sodium/potassium-transporting ATPase subunit beta [IPR000402]	0.8572374958595578	1.4536449812752907	0.1460447591929072	1.0	0.2300403568831389	2	P05026	1
+Mitochondrial carrier protein [IPR002067]	0.5491540405651953	1.4157964928799351	0.1568350967235279	1.0	0.2421840114972156	11	Q9HC21,Q9BQT8,O43808	3
+Cytochrome P450 [IPR001128]	0.8476316661146105	1.413947789663234	0.1573772327331863	1.0	0.2425412125269185	2	Q16850	1
+Sulfurtransferase TST/MPST-like [IPR045078]	0.8449817820470393	1.4029980641655484	0.1606174162084257	1.0	0.2459158739986426	2	P25325	1
+Ribosomal protein L25/L23 [IPR013025]	0.8446505465385927	1.401629415977577	0.161025938146802	1.0	0.2462384019425836	2	Q16540	1
+P-type ATPase [IPR001757]	0.6762458086415295	1.3772221668145144	0.1684435704728615	1.0	0.2539126841448608	6	P05023,P16615	2
+Bcl2-like [IPR002475]	0.837363365352771	1.371524397533789	0.1702115433698969	1.0	0.2553309932032432	2	Q9BXK5	1
+Bcl-2 family [IPR026298]	0.837363365352771	1.371524397533789	0.1702115433698969	1.0	0.2553309932032432	2	Q9BXK5	1
+TB2/DP1/HVA22-related protein [IPR004345]	0.9052352551358652	1.3229175720326247	0.1858627909987309	1.0	0.2714315619014529	3	Q00765,Q9H6H4	2
+Eukaryotic porin/Tom40 [IPR027246]	0.8442161087172656	1.3192864890458784	0.1870733530010351	1.0	0.2723499498603378	4	Q9Y277,O96008,P21796	3
+Adenylate kinase subfamily [IPR006259]	0.8820410868124656	1.238413466497262	0.2155627898900061	1.0	0.3029006549414791	3	P27144,Q9UIJ7	2
+Endoplasmic reticulum vesicle transporter [IPR045888]	0.7999337528983179	1.2172632740923166	0.2235040628001323	1.0	0.3095994148018401	2	Q9Y282	1
+Ribosomal protein L22/L17 [IPR001063]	0.7972838688307415	1.2063810646273276	0.2276705936982452	1.0	0.3138140128736399	2	Q9NWU5	1
+Histidine phosphatase superfamily, clade-1 [IPR013078]	0.7946339847631694	1.1955060416827643	0.2318893771486312	1.0	0.3178296439724506	2	P18669	1
+Translin family [IPR002848]	0.7936402782378319	1.1914298449469631	0.233484882397237	1.0	0.3194553534143378	2	Q15631	1
+Prefoldin alpha-like [IPR004127]	0.7913216296787047	1.181922999528889	0.2372362551051887	1.0	0.3232654675210983	2	Q99471	1
+Sec1-like protein [IPR001619]	0.5987045253833586	1.1656179852111934	0.2437689328965815	1.0	0.328533720155957	7	Q8WU76,Q96AX1	2
+2-oxoglutarate dehydrogenase E1 component [IPR011603]	0.7780722093408449	1.1277264190535916	0.2594354766684215	1.0	0.3447689807581041	2	Q96HY7	1
+Major facilitator superfamily [IPR011701]	0.7923651102752645	1.124591027787534	0.260762377463972	1.0	0.3462252757101822	4	Q14728,Q96ES6	2
+Glutathione Transferase family [IPR040079]	0.5145373952279496	1.1185106073957745	0.2633489787349143	1.0	0.3483050617053302	10	Q9H7Z7,O75431,O43708	3
+Pyrroline-5-carboxylate reductase [IPR000304]	0.7744286187479335	1.112865410149382	0.2657662377133092	1.0	0.3507095617175066	2	P32322	1
+Fumarate lyase family [IPR000362]	0.7731036767141491	1.107466514934948	0.2680922818754361	1.0	0.3527847284263046	2	P07954	1
+Porin, eukaryotic type [IPR001925]	0.843936381709752	1.1002984221057448	0.2712021194226262	1.0	0.3553533122044143	3	Q9Y277,P21796	2
+Peptidase M20 [IPR002933]	0.7704537926465754	1.0966772474915711	0.2727825059440532	1.0	0.3564710328782833	2	Q96KP4	1
+Aldo-keto reductase [IPR020471]	0.7661477310367729	1.0791700313050971	0.2805119366965094	1.0	0.3626054355640687	2	P14550	1
+Mitofusin family [IPR027094]	0.7654852600198798	1.0764795120846604	0.2817128589072917	1.0	0.3637560963607114	2	Q8IWA4	1
+Peptidase, FtsH [IPR005936]	0.7608479629016277	1.0576686148798922	0.2902065486395146	1.0	0.370432677407363	2	Q96TA2	1
+F-actin-capping protein subunit alpha [IPR002189]	0.7509108976482325	1.0175041286662911	0.3089136692035088	1.0	0.386927180099205	2	P52907	1
+TAF15/EWS/TLS family [IPR034870]	0.8124585818422886	0.9874212288940408	0.3234361815015405	1.0	0.3997698526373318	3	Q92804,Q01844	2
+Dephospho-CoA kinase [IPR001977]	0.7429612454455166	0.9855305069112604	0.3243635540407057	1.0	0.4007045277093889	2	Q8WVC6	1
+Synaptobrevin [IPR001388]	0.7409738323948378	0.9775610895725207	0.3282914498180584	1.0	0.4036942285982262	2	O75396	1
+Erlin1/2 [IPR033294]	0.7326929446836753	0.9444669474657426	0.3449310844287727	1.0	0.4186022128811596	2	O75477	1
+Prohibitin [IPR000163]	0.7230871149387272	0.9063231633191816	0.3647648287531515	1.0	0.4348067466068974	2	Q99623	1
+NSF attachment protein [IPR000744]	0.7191122888373693	0.8906236720776093	0.373131095302555	1.0	0.4418310035929597	2	P54920	1
+Luc7-related [IPR004882]	0.7741522437374941	0.8525136562022357	0.3939290627583869	1.0	0.4587999681181013	3	Q9Y383	1
+Paraneoplastic encephalomyelitis antigen [IPR002343]	0.7068565750248488	0.8425593350411691	0.3994749420006225	1.0	0.4638744242179847	2	O95319	1
+Transmembrane emp24 domain-containing protein [IPR015720]	0.7641291123710756	0.817815189323674	0.4134627234896713	1.0	0.4753410975293233	3	Q9BVK6	1
+Ribosomal protein L15 [IPR030878]	0.6985756873136866	0.8104038466357031	0.4177081077836129	1.0	0.4781776250275592	2	Q9P015	1
+Ribosomal protein S11 [IPR001971]	0.6975819807883474	0.8065639199609523	0.4199177676809675	1.0	0.4797596359888458	2	P82912	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]	0.6218328427328326	0.7986865490201853	0.4244721882054367	1.0	0.4830770017447386	5	Q96BP3,Q13356,Q9H2H8	3
+Serine-tRNA ligase, type1 [IPR002317]	0.6929446836700963	0.7886999353410421	0.4302874057278716	1.0	0.486730045942383	2	P49591	1
+Isocitrate dehydrogenase NAD-dependent [IPR004434]	0.7398939695162494	0.7352293305503488	0.4621998389566295	1.0	0.5120727983897159	3	O43837,P50213	2
+Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]	0.6700894335872882	0.7021303611877523	0.482597869639459	1.0	0.5262047567889957	2	Q13868	1
+G-protein alpha subunit, group I [IPR001408]	0.7243207422134081	0.6833027426097805	0.4944155615054473	1.0	0.5360939460325392	3	P63096,P04899	2
+Ras GTPase-activating protein-binding protein [IPR039539]	0.661146074859233	0.6690043897637	0.5034926777313973	1.0	0.5436699070891149	2	Q13283	1
+Macrophage migration inhibitory factor [IPR001398]	0.6575024842663217	0.6556428818299854	0.5120539276972877	1.0	0.5508815462956574	2	P30046	1
+Plakophilin/Delta catenin [IPR028435]	0.7147117296222638	0.651776114606862	0.5145456123564327	1.0	0.5533078909170459	3	Q99959,O00192	2
+Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]	0.6561775422325357	0.6508042124940984	0.5151728806054283	1.0	0.5537280594569824	2	O95478	1
+ATP:guanido phosphotransferase [IPR000749]	0.6472341835044804	0.6184343059369871	0.536289089740213	1.0	0.5753679005874605	2	P12532	1
+Dynein light chain, type 1/2 [IPR001372]	0.6313348790990486	0.5622334612784858	0.5739569661432538	1.0	0.6132511445647454	2	P63167	1
+14-3-3 protein [IPR000308]	0.5556649182530633	0.5515793028133877	0.5812366199536929	1.0	0.6207458609998153	5	P31946,P63104,Q04917	3
+Ribosomal protein S5/S7 [IPR000235]	0.6270288174892443	0.5473323301127903	0.5841504363518357	1.0	0.6235732656177143	2	P46782	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]	0.6809145129224621	0.544531777228438	0.5860755872835122	1.0	0.6253431858845497	3	Q9H2H8,O43447	2
+Protein transport protein Sec23 [IPR037364]	0.6144418681682775	0.5046234500315793	0.6138233361653729	1.0	0.6519784164987014	2	Q15436	1
+Heat shock protein Hsp90 family [IPR001404]	0.6122177447745418	0.4909983028215391	0.6234276479284677	1.0	0.6615793852223676	4	Q12931	1
+Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]	0.6545574590512927	0.4655604197359113	0.641530179646514	1.0	0.6795575341866468	3	P62906	1
+Protein disulphide isomerase [IPR005792]	0.6481113320079488	0.4469652344447703	0.6549001616806331	1.0	0.6930928022126411	3	P30101,P13667	2
+Beta tubulin [IPR002453]	0.4273674881232965	0.4201322919120197	0.674388813786887	1.0	0.7105059464784439	7	Q9BVA1	1
+Tubulin [IPR000217]	0.4273674881232965	0.4201322919120197	0.674388813786887	1.0	0.7105059464784439	7	Q9BVA1	1
+Heterogeneous nuclear ribonucleoprotein C [IPR017347]	0.582974494865861	0.4040349324806654	0.6861870315177159	1.0	0.7219612767563923	2	Q9UKM9	1
+Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]	0.5116480462489706	0.4029723162062056	0.6869685902889393	1.0	0.7224588813416024	5	P63096,P04899	2
+Prefoldin beta-like [IPR002777]	0.5455448824114073	0.2979118931348866	0.765770410476786	1.0	0.7995845365415504	2	Q9UHV9	1
+Mitochondrial Rho GTPase [IPR021181]	0.5163961576681158	0.227091614609081	0.820352504303103	1.0	0.8505071800591515	2	Q8IXI1	1
+Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]	0.5537051740296124	0.2152413175252466	0.8295791790434974	1.0	0.8589318258031081	3	Q9NQG5	1
+Peptidase M3A/M3B [IPR045090]	0.5520212060967518	0.2118980750368202	0.8321865523960765	1.0	0.861250538974012	3	Q99797,P52888	2
+Formate-tetrahydrofolate ligase, FTHFS [IPR000559]	0.4922159655515198	0.176942974663483	0.8595531822640021	1.0	0.8868285586954733	2	P11586	1
+26S proteasome regulatory subunit P45-like [IPR005937]	0.3678914124242762	0.1726167568569253	0.8629526795550642	1.0	0.8892613706184296	6	P43686,P62191,P62333,P17980	4
+Histidine phosphatase superfamily, clade-2 [IPR000560]	0.5306670378633158	0.1721629350737424	0.8633094362713367	1.0	0.8892613706184296	3	Q9UNW1	1
+Peptidase M24, methionine aminopeptidase [IPR001714]	0.4650546538589096	0.130222821572662	0.8963901393144034	1.0	0.920776356355866	2	P50579	1
+UDPGP family [IPR002618]	0.4554488241139557	0.1161191864634299	0.9075580830756856	1.0	0.9301620453088884	2	Q16222	1
+Proteasome alpha-type subunit [IPR023332]	0.3176552056132558	0.0958892061527949	0.9236085673182548	1.0	0.9439295410382146	7	O14818,P60900,P28066	3
+Syntaxin [IPR045242]	0.436906796168803	0.091856669594115	0.9268119185076844	1.0	0.9466259603955014	4	Q9UNK0,O15400	2
+Transcriptional repressor p66 [IPR040386]	0.4345809870818274	0.0896856577821316	0.928537013439994	1.0	0.9479743342621132	2	Q86YP4	1
+HAD-superfamily hydrolase, subfamily IIA [IPR006357]	0.4651675823523146	0.0813801834397063	0.9351396081565432	1.0	0.9542989636854698	3	Q9H0R4	1
+Bicarbonate transporter, eukaryotic [IPR003020]	0.4166942696257134	0.0713708426341894	0.9431026146229096	1.0	0.9608058260266096	2	Q9Y6M7	1
+Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]	0.4150380920834809	0.0698658988937185	0.9443003955196124	1.0	0.9611335764832228	2	Q9UKU0	1
+Aminoacyl-tRNA synthetase, class Ic [IPR002305]	0.4443339960238508	0.0619057567101654	0.9506378831015476	1.0	0.966669017027376	3	P23381,P54577	2
+Peroxisomal acyl-coenzyme A oxidase [IPR034171]	0.4051010268300887	0.0614790746835575	0.9509776788611906	1.0	0.966669017027376	2	Q15067	1
+Acyl-CoA oxidase [IPR012258]	0.4051010268300887	0.0614790746835575	0.9509776788611906	1.0	0.966669017027376	2	Q15067	1
+Mesoderm induction early response protein/metastasis-associated protein [IPR040138]	0.4410205434062231	0.0591896869645298	0.9528010238519604	1.0	0.9676820810574576	3	Q13330,Q9BTC8	2
+Peptidase S9A, prolyl oligopeptidase [IPR002470]	0.4011262007287306	0.0584228353778837	0.9534118258343484	1.0	0.9678825170330484	2	Q4J6C6	1
+Ribosomal protein L7/L30 [IPR039699]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9762547848167008	2	Q6DKI1	1
+Ribosomal protein L7, eukaryotic [IPR005998]	0.3792646571712575	0.0444093689577451	0.9645780936698116	1.0	0.9762547848167008	2	Q6DKI1	1
+Malic oxidoreductase [IPR001891]	0.3448161642928243	0.0303577665423035	0.9757817267350744	1.0	0.9858890903266332	2	P23368	1
+Ribosomal protein L3 [IPR000597]	0.3345478635309813	0.0276530133604529	0.9779388992632334	1.0	0.9868804292349764	2	P39023	1
+Ubiquitin conjugation factor E4 [IPR045132]	0.3309042729380697	0.0268246602776001	0.9785995842355788	1.0	0.9870321528201164	2	O95155	1
+HnRNP R/Q splicing factor [IPR006535]	0.3807157057654006	0.025334187235304	0.9797884052053936	1.0	0.987380394569878	3	O43390,A0AV96	2
+Clathrin adaptor, mu subunit [IPR001392]	0.3690683409448957	0.0215996375332731	0.9827673226716976	1.0	0.9895304526341694	3	Q96CW1	1
+Copine [IPR045052]	0.3503974010008928	0.0199157821772293	0.9841105552853532	1.0	0.9900666795836708	4	Q99829	1
+Tricarboxylate/iron carrier [IPR004686]	0.3627716186490319	0.0198716834193746	0.9841457340415216	1.0	0.9900666795836708	3	Q96NB2	1
+ATP-dependent 6-phosphofructokinase [IPR022953]	0.3442677269715005	0.0158154515868368	0.987381621394968	1.0	0.9916174927866238	3	P17858,P08237	2
+ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]	0.3442677269715005	0.0158154515868368	0.987381621394968	1.0	0.9916174927866238	3	P17858,P08237	2
+ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]	0.3442677269715005	0.0158154515868368	0.987381621394968	1.0	0.9916174927866238	3	P17858,P08237	2

interpro_homologous_superfamily/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Thioredoxin-like superfamily [IPR036249]"}