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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:80f34e0c5df072a1427b24b318076611610bd3372ffc0f7907185f3a30fbab78
+size 73396

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.709090909090909
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C265/C265_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.8768049155145907	1.7813892606306136	0.0748488814408108	0.9861421038114776	0.3782983538409338	3	P10619,Q9HB40	2
+Histidine acid phosphatase active site [IPR033379]	0.832616707616717	0.9269337164225346	0.3539609501266838	0.9999999999633368	0.6675236401456812	2	Q9NPH0	1
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7825552825552912	0.7487203579368381	0.4540257707423003	0.9999999999999964	0.7344534526713682	2	Q7LG56	1
+ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]	0.4496314496314607	0.045963610755451	0.9633392536495092	1.0	0.9890418260958608	2	P53597	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP7", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPK9", "MARK2", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME3", "NME6", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CTSA", "RRM2B", "SCPEP1", "SUCLG1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:8b2748b60bc394ef3d3c3f564a75d4340414622df052b03b32eee5b030fa40a4
+size 73012

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.6875
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C265/C265_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.7486645803831196	1.7676791952105868	0.0771145499884315	0.923311618893856	0.3690512782869502	5	O43847,Q10713	2
+EF-Hand 1, calcium-binding site [IPR018247]	0.5589169051908379	0.7714120494539793	0.4404627352338348	0.9999999914782556	0.7830448626379286	42	O95302,P43304,O43852,Q02818,P80303,P04632,Q6NUK1,Q14257,Q9Y680,Q96AY3,Q8IXI1,P41208,Q9NWM8	13

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1"], "leading_proteins": ["CALU", "CAPNS1", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GPD2", "NRDC", "NUCB1", "NUCB2", "PMPCA", "RCN2", "RHOT2", "SLC25A24"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Syntaxin/epimorphin, conserved site [IPR006012]", "1": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:9b001bf8d6f2411332b51b41a3a6ec1daf7fbd333c2be247ea67560ad006d1d4
+size 75913

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 280,
+    "title": "Average number of proteins per term",
+    "value": 2.7035714285714287
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C265/C265_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,27 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tetraspanin, conserved site [IPR018503]	0.9582181259600608	2.103721434579085	0.0354027535785621	0.999958610994312	0.6305306122251725	3	Q9H1Z9,O60637	2
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.9557603686635938	2.094117144244738	0.0362495462049761	0.9999676341695511	0.6305306122251725	3	Q8N4Q0,Q99536	2
+Syntaxin/epimorphin, conserved site [IPR006012]	0.707076923076911	1.7066362945286473	0.0878896747732365	0.9999999999934948	0.6305306122251725	8	Q13190,O15400,Q86Y82,O43752,Q9P2W9,O60499,Q13277	7
+Haem oxygenase conserved site [IPR018207]	0.9889434889434888	1.5142255710143118	0.129968638288084	1.0	0.6305306122251725	2	P09601	1
+Guanylate kinase, conserved site [IPR020590]	0.6149934194603737	1.2823500216470167	0.1997198879401285	1.0	0.7262541379641037	7	Q14168	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.9103194103194152	1.2157807499030302	0.2240684537787103	1.0	0.7381078477416341	2	Q16836	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.7016897081413165	1.070486577617985	0.2844003474708128	1.0	0.8050532913492006	3	P08238,P14625	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.5708415771669255	1.0575714834376395	0.2902508490391975	1.0	0.8050532913492006	8	P49721,P28072,P20618	3
+Intermediate filament protein, conserved site [IPR018039]	0.5267716493808179	0.8465031513515918	0.3972721165934783	1.0	0.8697363174943028	8	P07196,P08670,P07197	3
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.5573234743902509	0.77978894048293	0.4355151171519364	1.0	0.8758980002423795	4	Q9H3P7	1
+Sterol reductase, conserved site [IPR018083]	0.7850122850122943	0.7572532538023011	0.448898150995483	1.0	0.8758980002423795	2	Q14739	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.5221266133988962	0.6318750838392873	0.5274685057605906	1.0	0.9284875906011688	4	Q96SU4,Q9BXB4,Q9BZF1	3
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.4964495303720811	0.6234533762089874	0.5329866315829315	1.0	0.9284875906011688	5	P48735	1
+Clathrin adaptor complex, small chain [IPR000804]	0.5502304147465363	0.492943079492152	0.6220528069181133	1.0	0.9737529445241592	3	P53680,P61923	2
+DnaJ domain, conserved site [IPR018253]	0.4494895926313955	0.4775937025426274	0.6329394139407034	1.0	0.9737529445241592	9	Q99543,Q96KC8,Q9Y2G8,Q9NVH1	4
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.6821253071253162	0.4284587591814526	0.6683171528319396	1.0	0.990085091516738	2	P04439	1
+Thioredoxin, conserved site [IPR017937]	0.4464775148461324	0.4260033043795394	0.6701054381970368	1.0	0.990085091516738	12	Q9H3N1,O95881,Q9H1E5	3
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6787469287469321	0.4189120088414127	0.6752804402796508	1.0	0.990085091516738	2	P10644	1
+14-3-3 protein, conserved site [IPR023409]	0.4163591635916417	0.37847943689704	0.7050744666650648	1.0	1.0	6	P62258,P61981,P31946,P63104,Q04917	5
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.6640049140049168	0.3784145676598991	0.7051226479703072	1.0	1.0	2	P25325	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.4921658986175029	0.3104554242135709	0.7562146522371938	1.0	1.0	3	O00429,P50570	2
+ABC transporter-like, conserved site [IPR017871]	0.3861823612690736	0.1867141851070482	0.8518847335840878	1.0	1.0	12	Q03518	1
+ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]	0.4496314496314607	0.045963610755451	0.9633392536495092	1.0	1.0	2	P53597	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.3370199692780261	0.0314577312361664	0.974904501034704	1.0	1.0	3	P26583,P09429	2
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.3308755760368587	0.026947050619591	0.9785019661593256	1.0	1.0	3	Q9Y2T2,Q9BXS5	2
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.3230958230958176	0.0206543429509978	0.983521390288522	1.0	1.0	2	O15160	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXO3", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK9", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PML", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX16", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP32", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACBD3", "AP1M1", "AP2S1", "AP3M1", "COPZ1", "DNAJC1", "DNAJC11", "DNAJC16", "DNAJC2", "DNM1L", "DNM2", "HADH", "HLA-A", "HMGB1", "HMGB2", "HMOX1", "HSP90AB1", "HSP90B1", "IDH2", "LBR", "MPP2", "MPST", "NEFL", "NEFM", "OSBPL11", "OSBPL8", "OSBPL9", "POLR1C", "PRKAR1A", "PSMB1", "PSMB2", "PSMB6", "STX10", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLG1", "TAP1", "TMX1", "TMX4", "TSPAN10", "TSPAN3", "TXNDC12", "VAT1", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Dynamin, N-terminal [IPR045063]", "1": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "2": "EF-hand domain [IPR002048]", "3": "RNA recognition motif domain [IPR000504]", "4": "Target SNARE coiled-coil homology domain [IPR000727]", "5": "14-3-3 domain [IPR023410]", "6": "RNA recognition motif domain, eukaryote [IPR003954]", "7": "K Homology domain, type 1 [IPR004088]", "8": "K Homology domain [IPR004087]", "9": "MPN domain [IPR037518]", "10": "AP complex, mu/sigma subunit [IPR022775]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:382401e00306c47e2b591b2a6d0fc597ce152d07287e04b5018fb3087090a291
+size 115058

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Polyketide synthase, enoylreductase domain [IPR020843]	4	6	2.6520787869917317	0.0079997872509343	1.6189320388349515	6.283980582524272	0.4837477775906041	0.3583565743712875	1.2357658783365448	1.1656223303878015	1.2317099658487027	0.2921137785685181	3.3521637524966083e-06	0.0012601973854463	0.0048484802924912	3.419148340727646e-06	9.477724444731584e-05
+Aminopeptidase N-like , N-terminal domain [IPR045357]	4	6	2.425886389862781	0.015271049995617	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	2.214766218704514e-05	1.0	0.075113296023457	2.2502069418558096e-05	1.2976991690069218e-05
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	4	6	2.425886389862781	0.015271049995617	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	2.214766218704514e-05	1.0	0.075113296023457	2.2502069418558096e-05	1.2976991690069218e-05
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	6	2.4097279626072643	0.0159644191838399	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0331187861076589	0.0573151884822011	0.0057815105752346	0.0333651833289618	0.0001560226497295
+Alcohol dehydrogenase, N-terminal [IPR013154]	2	5	2.3103027860388736	0.0208713968010434	1.3762135922330097	5.245145631067961	0.6000738304798152	0.3870290227769069	1.1994000251783288	0.9246362329357484	1.1062357688130569	0.3020782188917261	0.0010713621736615	0.0432957136582515	0.0841007109914387	0.0010839430889874	0.0076273123324074
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	4	10	2.1879005824881306	0.0286768448705856	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0002054625318554	0.0619434524836269	0.0002366501305723	9.149704100094396e-06	0.0002434795729679
+TRAM/LAG1/CLN8 homology domain [IPR006634]	3	5	2.1513242542006155	0.031450615171225	1.691747572815534	3.3592233009708736	1.3447142040916915	0.1822595206051251	1.014281444620711	0.9789470163478144	1.2723870690026748	0.2262567589818981	0.0233125205204954	1.0	1.0	0.0234889728544392	0.0009048869233579

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 2644,
+    "title": "Average number of proteins per term",
+    "value": 2.18910741301059
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C265/C265_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,202 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Polyketide synthase, enoylreductase domain [IPR020843]	0.9167894281844264	2.6520787869917313	0.0079997872509343	0.9999999994014404	0.7204777103011879	6	Q8N4Q0,Q8WWV3,Q14914,Q99536	4
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8633280115329767	2.425886389862781	0.015271049995617	1.0	0.7204777103011879	6	Q9UIQ6,Q9NZ08,Q6P179,P09960	4
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8633280115329767	2.425886389862781	0.015271049995617	1.0	0.7204777103011879	6	Q9UIQ6,Q9NZ08,Q6P179,P09960	4
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8595649260937231	2.4097279626072643	0.0159644191838399	1.0	0.7204777103011879	6	O00264,Q8WUJ1,O15173,O43169	4
+FAD dependent oxidoreductase [IPR006076]	0.9196934508385464	2.346594053393253	0.0189458838711673	1.0	0.7204777103011879	4	Q96CU9,Q9H9P8	2
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.8734895537507057	2.3103027860388736	0.0208713968010434	1.0	0.7204777103011879	5	Q8N4Q0,Q99536	2
+ERAP1-like C-terminal domain [IPR024571]	0.893669330055317	2.2396188208566823	0.0251156797915295	1.0	0.7204777103011879	4	Q6P179,Q9NZ08,Q9UIQ6	3
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.816393141253122	2.1879005824881306	0.0286768448705856	1.0	0.7204777103011879	10	O95302,P62942,Q96AY3,Q9Y680	4
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8361784738674786	2.1513242542006155	0.031450615171225	1.0	0.7204777103011879	5	P27544,Q96CP7,Q15629	3
+Reticulon [IPR003388]	0.9508448540706596	2.0748836727856026	0.0379973172652374	1.0	0.7204777103011879	3	O95197,Q16799	2
+Zinc finger, CHHC-type [IPR012996]	0.898924731182795	1.8697801632353972	0.0615143521236247	1.0	0.7204777103011879	3	P31943,P55795	2
+Major facilitator superfamily domain [IPR020846]	0.7339709423824927	1.841684687371164	0.0655212853267006	1.0	0.7204777103011879	7	Q7L0J3,Q8NHS3,P53985,Q9H2V7	4
+L27 domain, C-terminal [IPR014775]	0.7621226804926653	1.8276153346970516	0.0676073027141455	1.0	0.7204777103011879	5	Q14168	1
+Peptidase M16, N-terminal [IPR011765]	0.7275647905450755	1.8122180332425395	0.0699525137265721	1.0	0.7204777103011879	7	Q5JRX3,O43847,Q10713	3
+Peptidase M16, C-terminal [IPR007863]	0.7275647905450755	1.8122180332425395	0.0699525137265721	1.0	0.7204777103011879	7	Q5JRX3,O43847,Q10713	3
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7914119758095672	1.8075725520772723	0.0706730533743893	1.0	0.7204777103011879	4	O15460,P13674	2
+SWIRM domain [IPR007526]	0.7885696878994696	1.7953122452623036	0.0726039651368692	1.0	0.7204777103011879	4	Q92922	1
+Dynamin, N-terminal [IPR045063]	0.6926302383274557	1.6390325326057795	0.1012064845244933	1.0	0.7204777103011879	8	O00429,O95140,Q9H223,O60313,Q8IWA4	5
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.6926302383274557	1.6390325326057795	0.1012064845244933	1.0	0.7204777103011879	8	O00429,O95140,Q9H223,O60313,Q8IWA4	5
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7177989548109532	1.629049205011203	0.1033026029454569	1.0	0.7204777103011879	5	P16615,P98194,P05023,Q9HD20	4
+Rab-GTPase-TBC domain [IPR000195]	0.6729964590979268	1.569734100985536	0.1164769842813289	1.0	0.7228678592861638	6	O60343,Q4KMP7,Q8TC07	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.6696376395654953	1.5421172610898322	0.1230451011427964	1.0	0.7303604455122539	7	O15460,P13674	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.6696376395654953	1.5421172610898322	0.1230451011427964	1.0	0.7303604455122539	7	O15460,P13674	2
+CS domain [IPR007052]	0.6612203533724121	1.502371165036365	0.1330012789331909	1.0	0.7334876671083769	7	Q9HB71	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7175783650891226	1.485430705118974	0.1374297669141064	1.0	0.7334876671083769	4	P16615,P98194,P05023	3
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7175783650891226	1.485430705118974	0.1374297669141064	1.0	0.7334876671083769	4	P16615,P98194,P05023	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6814382409145452	1.4638941389591844	0.1432228750581508	1.0	0.7378079548736197	5	O15228,Q8NF37,Q9NUQ2	3
+Syntaxin, N-terminal domain [IPR006011]	0.706207744314691	1.4352556444175562	0.1512142623360404	1.0	0.7470467704903312	4	Q86Y82,O15400,Q13277	3
+CBS domain [IPR000644]	0.6665267306310205	1.3956917511819769	0.1628073393760709	1.0	0.7632315696991695	5	Q8NE01	1
+GOLD domain [IPR009038]	0.6381846825964934	1.3930590401309182	0.163601937879692	1.0	0.7640795957854509	7	Q7Z7H5,P49755,Q9H3P7	3
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6361100811124318	1.3711399380852582	0.1703313370599319	1.0	0.7805130939106761	8	Q03518	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9453316953316956	1.348376719171285	0.1775372479561734	1.0	0.7913012457337052	2	Q8IV08	1
+Tim10-like [IPR004217]	0.7588325652841736	1.302923960283719	0.1926007229303405	1.0	0.7942423738446056	3	P62072,Q9Y5J9	2
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7554531490015327	1.2891359188511888	0.1973508381892172	1.0	0.7942423738446056	3	Q5BKZ1,Q9ULX6	2
+NOPS [IPR012975]	0.7517165545406499	1.2738925212436376	0.2027015092396296	1.0	0.7957308377214964	3	Q8WXF1	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.9103194103194152	1.2157807499030302	0.2240684537787103	1.0	0.8136310707956571	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.9103194103194152	1.2157807499030302	0.2240684537787103	1.0	0.8136310707956571	2	Q16836	1
+Potentiating neddylation domain [IPR005176]	0.9093980343980348	1.2123041260184626	0.2253959850630464	1.0	0.8136310707956571	2	Q96GG9	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.9023341523341526	1.1856782635744356	0.2357493817190015	1.0	0.824499160403492	2	O15460	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9011056511056568	1.1810530543478426	0.2375816477532897	1.0	0.8254451868685366	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9011056511056568	1.1810530543478426	0.2375816477532897	1.0	0.8254451868685366	2	Q9Y282	1
+BAG domain [IPR003103]	0.6422619909124797	1.1518035205126351	0.2494018208971953	1.0	0.8305168451091152	4	Q9UL15,O95429	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7209957718460256	1.1487648752202249	0.25065294658005	1.0	0.8305168451091152	3	P51114	1
+Fxr1, tudor domain [IPR041560]	0.7209957718460256	1.1487648752202249	0.25065294658005	1.0	0.8305168451091152	3	P51114	1
+Agenet-like domain [IPR008395]	0.7209957718460256	1.1487648752202249	0.25065294658005	1.0	0.8305168451091152	3	P51114	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7209957718460256	1.1487648752202249	0.25065294658005	1.0	0.8305168451091152	3	P51114	1
+Peptidase M28 [IPR007484]	0.7142321451504863	1.1212980445580785	0.2621610176378377	1.0	0.8435434210096592	3	P02786	1
+ADCK3-like domain [IPR034646]	0.8842137592137611	1.1176413619244143	0.2637201959076285	1.0	0.8435434210096592	2	Q8NI60	1
+ABC1 atypical kinase-like domain [IPR004147]	0.8842137592137611	1.1176413619244143	0.2637201959076285	1.0	0.8435434210096592	2	Q8NI60	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7121566221608655	1.1128779686250017	0.2657608433059932	1.0	0.8435434210096592	3	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7121566221608655	1.1128779686250017	0.2657608433059932	1.0	0.8435434210096592	3	P04439	1
+Immunoglobulin C1-set [IPR003597]	0.7121566221608655	1.1128779686250017	0.2657608433059932	1.0	0.8435434210096592	3	P04439	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7121566221608655	1.1128779686250017	0.2657608433059932	1.0	0.8435434210096592	3	P04439	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8756142506142515	1.0855103187473965	0.2776956959904999	1.0	0.8566177353782224	2	O60506	1
+Guanylate kinase-like domain [IPR008144]	0.5690435304154442	1.0489215858498862	0.2942142097833791	1.0	0.865839671962164	8	Q14168	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.5690435304154442	1.0489215858498862	0.2942142097833791	1.0	0.865839671962164	8	Q14168	1
+Band 7 domain [IPR001107]	0.5687083449885884	1.0473092691276855	0.2949569624205739	1.0	0.865839671962164	8	O75955,P27105,Q99623	3
+CARG-binding factor, N-terminal [IPR012956]	0.8642506142506164	1.0432365915868942	0.2968387301515016	1.0	0.865839671962164	2	Q99729	1
+Fibronectin type II domain [IPR000562]	0.6926853825110677	1.0341298561880226	0.3010754603559347	1.0	0.8690704765570579	3	Q9UBG0	1
+L27 domain [IPR004172]	0.5630832000117995	1.033403937312704	0.3014149046723342	1.0	0.8690704765570579	7	Q14168	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6907004607447389	1.0261312448384026	0.3048297244291345	1.0	0.8690704765570579	3	Q9UL46	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6907004607447389	1.0261312448384026	0.3048297244291345	1.0	0.8690704765570579	3	Q9UL46	1
+Rhodanese-like domain [IPR001763]	0.6136521363609293	1.025194675095807	0.3052713402789806	1.0	0.8690704765570579	4	Q99956,P25325	2
+Zinc finger, RanBP2-type [IPR001876]	0.5666077734052999	1.0244638317359855	0.3056162457229048	1.0	0.8690704765570579	9	Q01844,P35637,Q92804	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.856572481572485	1.014807437950275	0.3101976275056706	1.0	0.8691259510885148	2	P98179	1
+CHCH [IPR010625]	0.8544226044226104	1.0068683890443952	0.3139980245393929	1.0	0.8693306564211047	2	Q8N4Q1	1
+Syntaxin 6, N-terminal [IPR015260]	0.8538083538083598	1.0046018566052064	0.3150886029254653	1.0	0.8696182318736226	2	O43752	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8492014742014764	0.9876286215055098	0.3233345636139124	1.0	0.8804290280073991	2	Q9NVI7	1
+CNNM, transmembrane domain [IPR002550]	0.8452088452088489	0.9729565639411578	0.3305748904791361	1.0	0.8860441147877675	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.8452088452088489	0.9729565639411578	0.3305748904791361	1.0	0.8860441147877675	2	Q8NE01	1
+Exportin-2, central domain [IPR013713]	0.6731292614858396	0.9556221126031896	0.3392631856154435	1.0	0.88785133794759	3	O95373	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8399877149877182	0.953826195831843	0.3401716270635693	1.0	0.88785133794759	2	Q92945	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5870716721379664	0.9084769919155504	0.3636262643608923	1.0	0.8971888709211966	4	P51665	1
+CTLH, C-terminal LisH motif [IPR006595]	0.5869636664921605	0.908005457875606	0.3638753380714279	1.0	0.8971888709211966	4	Q9UL63,Q9NWU2	2
+OCRE domain [IPR041591]	0.6589861751152019	0.8993354774900424	0.3684739957153828	1.0	0.9007207434346728	3	P98175,P52756	2
+Legume-like lectin [IPR005052]	0.8197174447174445	0.8802265194536907	0.3787366098663485	1.0	0.9118251672990768	2	P49257	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.8148034398034409	0.8625625227294104	0.3883780433323092	1.0	0.9118251672990768	2	O95140	1
+Heat shock chaperonin-binding [IPR006636]	0.5475902306562759	0.8501237730694394	0.3952562757800706	1.0	0.9118251672990768	5	Q9UHD9,Q9NRR5	2
+Intermediate filament, rod domain [IPR039008]	0.5267716493808179	0.8465031513515918	0.3972721165934783	1.0	0.9118251672990768	8	P07196,P08670,P07197	3
+PTB/PI domain [IPR006020]	0.5458610553183978	0.8423058163989741	0.39961679618846	1.0	0.9118251672990768	5	O60343,Q9Y3P9,Q8NEU8	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.5688599034131269	0.8293819986984083	0.4068882843785935	1.0	0.9131878708838014	4	P07196,P08670	2
+LEM domain [IPR003887]	0.5172465881215699	0.8289154963949564	0.4071522259556821	1.0	0.9131878708838014	6	Q86XL3,P50402	2
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8052825552825642	0.8285601660224838	0.4073533362393715	1.0	0.9131878708838014	2	Q13505	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8052825552825642	0.8285601660224838	0.4073533362393715	1.0	0.9131878708838014	2	Q13505	1
+RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]	0.800982800982805	0.8133058925244896	0.416042699464197	1.0	0.9167327535817356	2	Q96DH6	1
+RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]	0.800982800982805	0.8133058925244896	0.416042699464197	1.0	0.9167327535817356	2	Q96DH6	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.5648831194761681	0.812236375292737	0.4166560108722061	1.0	0.9167327535817356	4	P08238,P14625	2
+MIT domain [IPR007330]	0.7997542997543062	0.8089596892073194	0.4185383335493453	1.0	0.9167327535817356	2	Q6PHR2	1
+Death domain [IPR000488]	0.6345276310483567	0.8032823463196145	0.4218115592492482	1.0	0.9167327535817356	3	Q96FV9	1
+START domain [IPR002913]	0.7979115479115548	0.802450745513582	0.422292269075903	1.0	0.9167327535817356	2	Q9NQZ5	1
+Chromo shadow domain [IPR008251]	0.6297411603224395	0.7847147071914717	0.4326208578141033	1.0	0.9167327535817356	3	P83916	1
+Chromo domain subgroup [IPR017984]	0.6297411603224395	0.7847147071914717	0.4326208578141033	1.0	0.9167327535817356	3	P83916	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.5573234743902509	0.77978894048293	0.4355151171519364	1.0	0.9197300077873164	4	Q9H3P7	1
+Glutamine amidotransferase type 2 domain [IPR017932]	0.6273425499231893	0.7754420839662265	0.4380784757159808	1.0	0.9200746252604032	3	P08243,Q06203	2
+SCP2 sterol-binding domain [IPR003033]	0.6270018299205306	0.7741267045136334	0.4388558668781082	1.0	0.9203963377283132	3	Q6YN16	1
+Alpha/beta hydrolase fold-1 [IPR000073]	0.5083532027670539	0.7730838102955124	0.4394727817917676	1.0	0.9207337837222136	7	Q9NUJ1	1
+Ricin B, lectin domain [IPR000772]	0.5254155571766896	0.7505543059345939	0.4529209296241698	1.0	0.930930147218616	5	Q10472	1
+Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]	0.6201235938837591	0.7476712669211499	0.4546584663975772	1.0	0.930930147218616	3	P11940	1
+SUN coiled coil domain 2 [IPR040994]	0.7754914004914005	0.7243328747854839	0.4688613989023071	1.0	0.9364299545281874	2	O94901	1
+Acyltransferase, C-terminal domain [IPR032098]	0.7730343980344015	0.71590225572578	0.4740517055114992	1.0	0.936765851548882	2	Q9NUQ2	1
+Glutamine amidotransferase [IPR017926]	0.5395056329783743	0.7041837805315326	0.4813183304542108	1.0	0.938214431763296	4	P17812	1
+EF-hand domain [IPR002048]	0.5444140920316782	0.6979991018486795	0.4851777557526611	1.0	0.940121252278421	48	Q8IYU8,Q8NF37,O95302,O43852,P43304,Q02818,P80303,P04632,Q6NUK1,Q14257,Q9Y680,Q03001,O75071,Q8IXI1,P41208,Q9NWM8,Q96AY3	17
+MD-2-related lipid-recognition domain [IPR003172]	0.7592137592137695	0.6690124877263518	0.5034875120603954	1.0	0.9441283559487132	2	P17900	1
+EH domain-containing protein, N-terminal [IPR031692]	0.757985257985256	0.6648903206978297	0.5061206471074284	1.0	0.9464974482066753	2	Q9H223	1
+Domain of unknown function DUF5600 [IPR040990]	0.757985257985256	0.6648903206978297	0.5061206471074284	1.0	0.9464974482066753	2	Q9H223	1
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.7570638820638796	0.6618038081416545	0.5080969652547238	1.0	0.9464974482066753	2	Q9NWU2	1
+CRA domain [IPR013144]	0.7570638820638796	0.6618038081416545	0.5080969652547238	1.0	0.9464974482066753	2	Q9NWU2	1
+SUN domain [IPR012919]	0.5881733468577682	0.6276300545457271	0.530246315533033	1.0	0.9543089015568852	3	O94901	1
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.4964495303720811	0.6234533762089874	0.5329866315829315	1.0	0.9573482703160808	5	P48735	1
+LEM-like domain [IPR013146]	0.7407862407862459	0.6080322552646141	0.5431660812301073	1.0	0.963846388437855	2	P42167	1
+EB1, C-terminal [IPR004953]	0.7349508599508656	0.5891245965690078	0.5557776945896782	1.0	0.9744537297712924	2	Q15555	1
+EF-hand, Ca insensitive [IPR014837]	0.5741935483870899	0.5768682476458451	0.5640284617381597	1.0	0.9791800740877836	3	O43707,Q13813	2
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.5079901659496032	0.574338199754743	0.5657389642010344	1.0	0.97986267537157	4	P18031,Q9H3S7,P10586	3
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.5079901659496032	0.574338199754743	0.5657389642010344	1.0	0.97986267537157	4	P18031,Q9H3S7,P10586	3
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.4609795965785676	0.5555421497367681	0.57852388823436	1.0	0.983716368121411	7	O00303,Q92905,P51665	3
+RNA recognition motif domain [IPR000504]	0.2700209198747445	0.5553192099450052	0.5786763416028327	1.0	0.983716368121411	121	Q9P2K5,Q01085,P31942,O43347,P22626,O43390,P98179,Q9UHX1,Q8TBF4,Q9BWF3,P23246,P31943,P55795,Q15056,Q96DH6,Q14103,P35637,Q01844,P52597,P51991,Q14011,Q99729,Q8WXF1,P26368,P38159,P62995,O14979,P09012,Q92804,P52756,O60506	31
+Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]	0.723894348894351	0.5538764148549024	0.5796634272061869	1.0	0.983716368121411	2	Q93100	1
+GH15-like domain [IPR011613]	0.723894348894351	0.5538764148549024	0.5796634272061869	1.0	0.983716368121411	2	Q93100	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.4715294391713057	0.5496372029377032	0.5825682364455229	1.0	0.9848532079040682	11	Q13190,O15400,Q86Y82,O43752,O60499,Q13277	6
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.4556402111443212	0.5458997505356208	0.585134849857311	1.0	0.986599047847528	6	Q8N4Q0,Q14914	2
+PABP, RNA recognition motif 2 [IPR045305]	0.7189803439803427	0.5384650561518374	0.5902560233778456	1.0	0.9877448897538124	2	P11940	1
+Phox homology [IPR001683]	0.4581050861804105	0.4894774006844352	0.6245037503758668	1.0	1.0	11	Q92543,Q9Y5X3	2
+HR1 rho-binding domain [IPR011072]	0.5490015360983029	0.4887564250827012	0.6250141511510856	1.0	1.0	3	Q13464,O75116	2
+Copine, C2B domain [IPR037768]	0.5483870967741858	0.4866676860191375	0.6264938484650728	1.0	1.0	3	Q99829,O75131	2
+Copine, C-terminal [IPR010734]	0.5483870967741858	0.4866676860191375	0.6264938484650728	1.0	1.0	3	Q99829,O75131	2
+Arf GTPase activating protein [IPR001164]	0.5456221198156606	0.4773066624520024	0.6331437674128242	1.0	1.0	3	Q8N6T3,Q8IYB5	2
+GRAM domain [IPR004182]	0.6962530712530759	0.4693997056195866	0.6387839587574371	1.0	1.0	2	Q969T9	1
+GCF, C-terminal [IPR022783]	0.6956388206388318	0.4675865055396446	0.6400803169327931	1.0	1.0	2	Q9Y5B6	1
+Zinc finger, CCHC-type [IPR001878]	0.443159805666808	0.463534480791403	0.6429813053694484	1.0	1.0	8	O95639,Q9NUD5,Q8TBF4	3
+Marvel domain [IPR008253]	0.693796068796076	0.4621646085551699	0.6439632809997602	1.0	1.0	2	Q16625	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.6928746928747039	0.4594636807208733	0.6459012275365721	1.0	1.0	2	P51114	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6787469287469321	0.4189120088414127	0.6752804402796508	1.0	1.0	2	P10644	1
+Ubiquitin system component CUE [IPR003892]	0.4665027658266777	0.4141808735099523	0.6787416481000514	1.0	1.0	4	Q9Y679,Q9H4L7,Q9H0E2	3
+Glycosyl transferase, family 1 [IPR001296]	0.5159330889626266	0.3810790513585664	0.7031445913075083	1.0	1.0	3	Q9BT22	1
+14-3-3 domain [IPR023410]	0.4163591635916417	0.37847943689704	0.7050744666650648	1.0	1.0	6	P62258,P61981,P31946,P63104,Q04917	5
+Importin-beta, N-terminal domain [IPR001494]	0.4351186678731722	0.3775134465302545	0.7057920734896184	1.0	1.0	12	O95373,Q92973,Q8TEX9,Q14974	4
+Nuclear transport factor 2 domain [IPR002075]	0.4520590043023997	0.3622364372811741	0.7171753528027569	1.0	1.0	4	Q9UN86,P61970,Q13283	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.4520590043023997	0.3622364372811741	0.7171753528027569	1.0	1.0	4	Q9UN86,P61970,Q13283	3
+GYF domain [IPR003169]	0.6532555282555308	0.3501309463513294	0.7262404271923868	1.0	1.0	2	O95400	1
+Lamin tail domain [IPR001322]	0.4992319508448459	0.3307992234844429	0.7407961474664058	1.0	1.0	3	Q03252,P20700	2
+CSN8/PSMD8/EIF3K [IPR033464]	0.4967741935483785	0.3236582577297737	0.7461967765987161	1.0	1.0	3	Q9UBQ5,Q99627	2
+GTPase effector domain [IPR020850]	0.4921658986175029	0.3104554242135709	0.7562146522371938	1.0	1.0	3	O00429,P50570	2
+Dynamin GTPase effector [IPR003130]	0.4921658986175029	0.3104554242135709	0.7562146522371938	1.0	1.0	3	O00429,P50570	2
+Dynamin stalk domain [IPR000375]	0.4921658986175029	0.3104554242135709	0.7562146522371938	1.0	1.0	3	O00429,P50570	2
+RNA recognition motif domain, eukaryote [IPR003954]	0.4166512866405362	0.2664311662628388	0.7899071651694212	1.0	1.0	15	P38159,Q01085,P11940,Q01130,Q14011,Q9UHX1,Q8TBF4	7
+K Homology domain, type 1 [IPR004088]	0.4344632204356545	0.2650616529735874	0.7909619675274451	1.0	1.0	22	P61978,Q96AE4,P51114,Q06787,Q92945,Q96I24,Q9Y2W6	7
+RAP domain [IPR013584]	0.4721966205837083	0.2561818824588702	0.797810397643816	1.0	1.0	3	Q9NYY8,Q969Z0	2
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.4721966205837083	0.2561818824588702	0.797810397643816	1.0	1.0	3	Q9NYY8,Q969Z0	2
+FAST kinase leucine-rich [IPR010622]	0.4721966205837083	0.2561818824588702	0.797810397643816	1.0	1.0	3	Q9NYY8,Q969Z0	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.4685301156788076	0.2467581574118582	0.805095394778095	1.0	1.0	3	P21912	1
+DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]	0.4663315514776029	0.2411907559966482	0.8094072750965922	1.0	1.0	3	P49005	1
+ELMO domain [IPR006816]	0.6016584766584824	0.2305296207860266	0.8176802491704696	1.0	1.0	2	Q8IZ81	1
+Exosome complex component, N-terminal domain [IPR025721]	0.6007371007371063	0.2286528288183003	0.8191387606224896	1.0	1.0	2	Q9Y3B2	1
+Elp3/MiaB/NifB [IPR006638]	0.4543778801843223	0.2120377771744723	0.8320775624092962	1.0	1.0	3	Q5VV42,Q9NZB8	2
+Radical SAM [IPR007197]	0.4543778801843223	0.2120377771744723	0.8320775624092962	1.0	1.0	3	Q5VV42,Q9NZB8	2
+CRAL-TRIO lipid binding domain [IPR001251]	0.5850737100737168	0.1982048312990784	0.8428848076448079	1.0	1.0	2	P21359	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3861823612690736	0.1867141851070482	0.8518847335840878	1.0	1.0	12	Q03518	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.3930547019053502	0.1776690526401211	0.8589828909373018	1.0	1.0	4	O60884,Q96EY1,P25685	3
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5715601965602041	0.174172161922709	0.8617301626940856	1.0	1.0	2	O75694	1
+ROCK, Rho binding domain [IPR015008]	0.5654176904176984	0.1639377416741593	0.8697801554610818	1.0	1.0	2	O75116	1
+K Homology domain [IPR004087]	0.3954650566978425	0.1137387313149547	0.9094449085804844	1.0	1.0	22	P61978,Q96AE4,P51114,Q06787,Q92945,Q96I24,Q9Y2W6	7
+Myb domain [IPR017930]	0.3432727230132519	0.0952408969570811	0.9241234865345996	1.0	1.0	8	Q92922	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.3929339477726509	0.0936956973905889	0.925350888227748	1.0	1.0	3	O60884,Q96EY1	2
+eRF1 domain 1/Pelota-like [IPR005140]	0.5042997542997542	0.0850784163280572	0.9321990493572628	1.0	1.0	2	P62495	1
+eRF1 domain 2 [IPR005141]	0.5042997542997542	0.0850784163280572	0.9321990493572628	1.0	1.0	2	P62495	1
+eRF1 domain 3 [IPR005142]	0.5042997542997542	0.0850784163280572	0.9321990493572628	1.0	1.0	2	P62495	1
+HECT domain [IPR000569]	0.3369555942760176	0.0775099152042909	0.938217903812456	1.0	1.0	8	Q05086	1
+ALIX V-shaped domain [IPR025304]	0.4938574938574976	0.0755463933285149	0.9397799864338624	1.0	1.0	2	Q9H3S7	1
+BRO1 domain [IPR004328]	0.4938574938574976	0.0755463933285149	0.9397799864338624	1.0	1.0	2	Q9H3S7	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.3711807571813423	0.0646340630903867	0.9484653629782864	1.0	1.0	3	Q1KMD3	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.4794226044226173	0.0640660081953362	0.9489176677519786	1.0	1.0	2	Q14240	1
+Survival motor neuron [IPR010304]	0.4785012285012328	0.0633970097573538	0.9494503683312968	1.0	1.0	2	Q16637	1
+CoA-binding [IPR003781]	0.4496314496314607	0.045963610755451	0.9633392536495092	1.0	1.0	2	P53597	1
+Peptidase M41 [IPR000642]	0.4431818181818167	0.0429230521088224	0.965762872756856	1.0	1.0	2	Q9Y4W6	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4394963144963265	0.0413110412483475	0.9670479309422596	1.0	1.0	2	Q9Y305	1
+Putative WW-binding domain and destruction box [IPR033461]	0.4305896805896834	0.0377702687315895	0.9698708495654756	1.0	1.0	2	Q9ULX3	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.3251382913337465	0.0342688856618162	0.9726627359349476	1.0	1.0	4	Q8WVV9,Q9UKA9,P14866	3
+BTB/POZ domain [IPR000210]	0.3397849462365506	0.0336228885710221	0.9731778701449808	1.0	1.0	3	Q08380,Q96CX2	2
+Stromalin conservative domain [IPR020839]	0.4103194103194078	0.0313869679240788	0.9749609341219992	1.0	1.0	2	Q8WVM7	1
+STAG [IPR013721]	0.4103194103194078	0.0313869679240788	0.9749609341219992	1.0	1.0	2	Q8WVM7	1
+Ariadne domain [IPR045840]	0.393120393120398	0.0275020761126101	0.9780592839765684	1.0	1.0	2	Q9Y4X5	1
+TRIAD supradomain [IPR044066]	0.393120393120398	0.0275020761126101	0.9780592839765684	1.0	1.0	2	Q9Y4X5	1
+IBR domain [IPR002867]	0.393120393120398	0.0275020761126101	0.9780592839765684	1.0	1.0	2	Q9Y4X5	1
+Mad3/Bub1 homology region 1 [IPR013212]	0.3820638820638803	0.0256060334263457	0.979571573670907	1.0	1.0	2	O60566	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.3676289926289952	0.0237058404442518	0.9810872473153393	1.0	1.0	2	Q13641	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.3676289926289952	0.0237058404442518	0.9810872473153393	1.0	1.0	2	Q13641	1
+RuvB-like, AAA-lid domain [IPR041048]	0.3510442260442306	0.0221638355533589	0.9823172655471164	1.0	1.0	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.3510442260442306	0.0221638355533589	0.9823172655471164	1.0	1.0	2	Q9Y230	1
+Ubiquitin conjugation factor E4, core [IPR019474]	0.34582309582309	0.0217926205802226	0.982613380714477	1.0	1.0	2	O95155	1
+Thioredoxin-like fold [IPR012336]	0.3292383292383269	0.0208964064290858	0.9833282932534932	1.0	1.0	2	Q6DKJ4	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.3230958230958176	0.0206543429509978	0.983521390288522	1.0	1.0	2	O15160	1
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.3230958230958176	0.0206543429509978	0.983521390288522	1.0	1.0	2	O15160	1
+FF domain [IPR002713]	0.3101965601965534	0.0202668662772215	0.9838304872358868	1.0	1.0	2	O75400	1
+Extended PHD (ePHD) domain [IPR034732]	0.3188940092165829	0.0192816651229463	0.9846164103229228	1.0	1.0	3	O94880,Q03164	2
+MPN domain [IPR037518]	0.3205049261083621	0.0145876406020227	0.988361159576004	1.0	1.0	10	O43402,Q92905,Q8TAT6,Q15018,O00303,O15372,O00487,Q7L5N1,P51665	9
+AP complex, mu/sigma subunit [IPR022775]	0.2985854858548656	0.0071289062628596	0.9943120039360576	1.0	1.0	6	P53680,Q96CW1,Q9Y2T2,P61923,P61966	5
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.3033189920098377	0.0051055370372998	0.9959263885208104	1.0	1.0	4	P51784,Q86UV5,Q8NFA0	3
+Cold-shock (CSD) domain [IPR019844]	0.2804915514592858	0.0031680696406656	0.997472250374528	1.0	1.0	3	P67809,Q9Y2V2	2
+Cold shock domain [IPR011129]	0.2804915514592858	0.0031680696406656	0.997472250374528	1.0	1.0	3	P67809,Q9Y2V2	2
+Cold-shock protein, DNA-binding [IPR002059]	0.2804915514592858	0.0031680696406656	0.997472250374528	1.0	1.0	3	P67809,Q9Y2V2	2
+MRH domain [IPR044865]	0.299631223110022	0.0009380065462368	0.999251579168576	1.0	1.0	4	P14314,P20645,Q13438	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Major facilitator superfamily [IPR011701]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Major facilitator superfamily [IPR011701]", "1": "Syntaxin [IPR045242]", "2": "Proteasome, subunit alpha/beta [IPR001353]", "3": "14-3-3 protein [IPR000308]"}