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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:663ffe54fb398d00a48a82cdd150a278451e143af8ec65af9fd85d605a79d0c2
+size 73245

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.709090909090909
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C266/C266_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.660657721469513	0.8784798939563269	0.3796833441871987	0.999999999996076	0.7458065689391404	3	P10619	1
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.4092165898617408	0.1185790761248319	0.9056088432077938	1.0	0.9946603674581422	3	Q8TBC4,Q9UBT2	2

interpro_active_site/selections.json

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+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP7", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPK9", "MARK2", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME3", "NME6", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["CTSA", "UBA2", "UBA3"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:96035e5949a80823bd9fba64e57468acad45c3078bf728c94d343ae1a13dd542
+size 73208

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M16, zinc-binding site [IPR001431]	2	5	1.977950746824216	0.0479342632743327	1.730582524271845	5.0	0.6776547957610433	0.4740055886775391	1.2118895823030245	0.0	0.8079860258854747	0.314626832259423	0.0499801394438941	0.0238038053541035	0.047623940504538	0.0055694485300755	0.0010568895936515

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.6875
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C266/C266_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.7993196494896359	1.977950746824216	0.0479342632743327	0.7923452122931698	0.5112988082595488	5	O43847,Q10713	2
+Beta tubulin, autoregulation binding site [IPR013838]	0.6795570620299047	1.5967203874893403	0.110328049025232	0.9762667750426404	0.5581833893846877	6	Q9BUF5,Q9BVA1,P07437	3

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1"], "leading_proteins": ["NRDC", "PMPCA", "TUBB", "TUBB2B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Kinesin motor domain, conserved site [IPR019821]", "1": "Zinc finger, RING-type, conserved site [IPR017907]", "2": "Guanylate kinase, conserved site [IPR020590]", "3": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:863ac8b9b8833e213f8af7db36186eb14cd6133cc0c19a96a680f394fbfd83b3
+size 76236

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 280,
+    "title": "Average number of proteins per term",
+    "value": 2.7035714285714287
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C266/C266_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,32 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7107719058273276	1.7079279898553212	0.0876497048812983	0.9999999999929976	0.5326181677080168	8	P49721,Q99436,P28072,P28074	4
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8433179723502289	1.6038081003091973	0.1087563585351265	0.99999999999999	0.5326181677080168	3	Q99536,Q8N4Q0	2
+Tubulin, conserved site [IPR017975]	0.6795570620299047	1.5967203874893403	0.110328049025232	0.999999999999994	0.5326181677080168	6	Q9BUF5,Q9BVA1,P07437	3
+Haem oxygenase conserved site [IPR018207]	0.98433660933661	1.4523631779337451	0.1464006491314795	1.0	0.6210936629820344	2	P30519	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.6903640988306019	1.3534655689608348	0.1759069424909078	1.0	0.6461033402420776	4	P45984,P28482	2
+Oxysterol-binding protein, conserved site [IPR018494]	0.682108814407911	1.3175886244368122	0.1876413956878155	1.0	0.6461033402420776	4	Q9BZF1	1
+Kinesin motor domain, conserved site [IPR019821]	0.6387503168317316	1.3057300353905608	0.1916443801117648	1.0	0.6461033402420776	12	O95239,Q15058,Q9Y496,Q99661,Q96Q89,Q9BW19	6
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.8593366093366119	0.9878877225523258	0.3232076389552121	1.0	0.7604885622475579	2	P01889	1
+Intermediate filament protein, conserved site [IPR018039]	0.5324463511794509	0.8668588225190058	0.3860193676314014	1.0	0.8212726936459074	8	P08670,P48681,P07196	3
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.8191031941031996	0.8435804730551107	0.3989038797708693	1.0	0.8212726936459074	2	P25325	1
+Thioredoxin, conserved site [IPR017937]	0.5072250003266519	0.6822425561198212	0.4950855894920423	1.0	0.8943481616630441	12	Q9H1E5,P07237,Q9H3N1,O95881	4
+Clathrin adaptor complex, small chain [IPR000804]	0.5757296466973817	0.5637751762823969	0.5729071478617884	1.0	0.9380935754462032	3	P61923,P53680	2
+Tetraspanin, conserved site [IPR018503]	0.5612388623436759	0.5139723126203481	0.6072713484479191	1.0	0.9440430042672376	3	O60637	1
+DnaJ domain, conserved site [IPR018253]	0.4471118342000326	0.4668222822998452	0.6406270324564274	1.0	0.9440430042672376	9	Q8WXX5	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.4561447394678132	0.4570379426571342	0.6476437737501486	1.0	0.9440430042672376	12	Q14258,Q14527,O15344,Q9UPN9,P19474	5
+Serpin, conserved site [IPR023795]	0.5400921658986099	0.4441450223840895	0.6569377374980898	1.0	0.9440430042672376	3	P30740,P50454	2
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6931818181818182	0.4357339700330143	0.6630297560910703	1.0	0.9440430042672376	2	P13861	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.46614042827939	0.4261306528327829	0.6700126453862045	1.0	0.9440430042672376	4	Q9H3P7	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.4302526179380684	0.4138527125259819	0.6789819768996201	1.0	0.946280366167517	8	Q9P2W9,O43752	2
+ABC transporter-like, conserved site [IPR017871]	0.4425669703983765	0.4008635295740133	0.6885206023761357	1.0	0.9543849933926633	12	P08183	1
+Hexapeptide transferase, conserved site [IPR018357]	0.6667690417690464	0.3634667587873008	0.7162562400984716	1.0	0.9770380435395304	2	Q9Y5P6	1
+Guanylate kinase, conserved site [IPR020590]	0.4121808674254134	0.3586717306503921	0.7198406787914111	1.0	0.9770380435395304	7	Q14168,Q00013,O14936,Q12959,Q9NZW5,Q8N3R9	6
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.4130699488147945	0.3460713273020032	0.7292891110705781	1.0	0.9770380435395304	8	P51648	1
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.3480752937328111	0.1412412989132197	0.8876793212606251	1.0	1.0	7	P49748	1
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.5264127764127848	0.0971481400229855	0.9226087514184812	1.0	1.0	2	Q00796	1
+14-3-3 protein, conserved site [IPR023409]	0.3170356703567107	0.0736059857113876	0.941323908152958	1.0	1.0	6	P27348,P61981,P63104,Q04917,P62258	5
+Ubiquitin interacting motif [IPR003903]	0.326367547633685	0.0662974410373682	0.9471410205009004	1.0	1.0	4	P42566,P55036,Q9Y6I3	3
+Ribosomal protein S2, conserved site [IPR018130]	0.4941646191646313	0.0656913375542335	0.9476235691477316	1.0	1.0	2	P08865	1
+ATPase, AAA-type, conserved site [IPR003960]	0.3517986254052802	0.0384554794640729	0.9693245274472824	1.0	1.0	17	Q15645,Q8NB90,Q8NBU5	3
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.4090909090909128	0.0234064279859507	0.9813260776205964	1.0	1.0	2	Q9UBT2	1
+GHMP kinase, ATP-binding, conserved site [IPR006203]	0.2982186732186667	0.0130290973485858	0.9896045785017802	1.0	1.0	2	Q03426	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXO3", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK9", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PML", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX16", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP32", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ACADVL", "ACBD3", "ALDH3A2", "AP2S1", "ATAD1", "CASK", "COPZ1", "DLG1", "DNAJC9", "EPN1", "EPS15", "GMPPB", "HLA-B", "HLTF", "HMOX2", "KIF14", "KIF20B", "KIF2C", "KIF3A", "KIF4A", "KIFC1", "MAPK1", "MAPK9", "MID1", "MPP1", "MPP2", "MPP5", "MPP6", "MPST", "MVK", "NEFL", "NES", "OSBPL8", "P4HB", "PRKAR2A", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSMD4", "RPSA", "SERPINB1", "SERPINH1", "SORD", "SPATA5", "STX18", "STX6", "TMX1", "TMX4", "TRIM21", "TRIM25", "TRIM33", "TRIP13", "TSPAN3", "TUBB", "TUBB2B", "TUBB6", "TXNDC12", "UBA2", "VAT1", "VIM", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Major facilitator superfamily domain [IPR020846]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Major facilitator superfamily domain [IPR020846]", "1": "Kinesin motor domain [IPR001752]", "2": "SET domain [IPR001214]", "3": "AGC-kinase, C-terminal [IPR000961]", "4": "K Homology domain, type 1 [IPR004088]", "5": "Gelsolin-like domain [IPR007123]", "6": "K Homology domain [IPR004087]", "7": "Sterile alpha motif domain [IPR001660]", "8": "Zinc finger, RanBP2-type [IPR001876]", "9": "Actin-depolymerising factor homology domain [IPR002108]", "10": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "11": "14-3-3 domain [IPR023410]", "12": "Zinc finger, RING-type [IPR001841]", "13": "Pleckstrin homology domain [IPR001849]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b95ac4d5c990435e00f12396c61079a599628793be5879dded3e20d39f7380cc
+size 117934

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	4	6	2.7113266199966213	0.0067014577843744	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	4.748744011618872e-06	0.0014481500629001	3.899978627501455e-06	5.522373670119844e-06	0.0001575214550341
+Major facilitator superfamily domain [IPR020846]	5	7	2.484217567281126	0.0129836455222116	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	1.0	1.0	1.0	0.0056128198685199	0.0027845492980534
+Aminopeptidase N-like , N-terminal domain [IPR045357]	4	6	2.3260706351412472	0.0200147827875607	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0027720744927096	0.0378187125466048	0.0025156479029566	0.0007187465088185	1.3106068439724131e-05
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	4	6	2.3260706351412472	0.0200147827875607	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0027720744927096	0.0378187125466048	0.0025156479029566	0.0007187465088185	1.3106068439724131e-05
+Peptidase M16, C-terminal [IPR007863]	4	7	2.093355420398847	0.0363174388020848	2.6067961165048543	7.0	0.7914914082442276	0.4366893661235884	1.5075062759483802	0.0	0.8715475629418188	0.3304871916560691	0.0692722054591515	0.0331691185540615	0.0660385900079411	0.0004573905935078	5.11944457815466e-06
+Peptidase M16, N-terminal [IPR011765]	4	7	2.093355420398847	0.0363174388020848	2.6067961165048543	7.0	0.7914914082442276	0.4366893661235884	1.5075062759483802	0.0	0.8715475629418188	0.3304871916560691	0.0692722054591515	0.0331691185540615	0.0660385900079411	0.0004573905935078	5.11944457815466e-06
+Rab-GTPase-TBC domain [IPR000195]	2	6	2.0096668862848084	0.0444664569050057	2.3859223300970873	5.796116504854369	0.1134162291169182	0.5173474563284153	1.6097686843979655	1.411528286266865	0.9657620081719772	0.3151054488100016	1.0	1.0	1.0	1.0	0.2535314416198171

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3258,
+    "annotations_size": 2644,
+    "title": "Average number of proteins per term",
+    "value": 2.18910741301059
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C266/C266_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,256 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.9328952146066825	2.7113266199966213	0.0067014577843744	0.9999999809898232	0.7412093339623087	6	O00264,O43169,O15173,Q8WUJ1	4
+Major facilitator superfamily domain [IPR020846]	0.8819444031721014	2.484217567281126	0.0129836455222116	0.999999999999999	0.7412093339623087	7	Q8NHS3,Q14728,Q9H2V7,P53985,O43826	5
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8417690436594923	2.3260706351412472	0.0200147827875607	1.0	0.7412093339623087	6	P55786,Q6P179,P09960,Q9NZ08	4
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8417690436594923	2.3260706351412472	0.0200147827875607	1.0	0.7412093339623087	6	P55786,Q6P179,P09960,Q9NZ08	4
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.8845929801381192	2.1770239776004296	0.0294787784738075	1.0	0.7412093339623087	4	P48147	1
+Peptidase M16, C-terminal [IPR007863]	0.7921685256678342	2.093355420398847	0.0363174388020848	1.0	0.7412093339623087	7	O43847,Q5JRX3,P22695,Q10713	4
+Peptidase M16, N-terminal [IPR011765]	0.7921685256678342	2.093355420398847	0.0363174388020848	1.0	0.7412093339623087	7	O43847,Q5JRX3,P22695,Q10713	4
+ERAP1-like C-terminal domain [IPR024571]	0.8626306084818692	2.0866806721666915	0.0369170095310651	1.0	0.7412093339623087	4	P55786,Q6P179,Q9NZ08	3
+BAG domain [IPR003103]	0.8509526736324531	2.038310867875259	0.0415188537006567	1.0	0.7412093339623087	4	O95817,O95429,Q9UL15	3
+Rab-GTPase-TBC domain [IPR000195]	0.7699161980248007	2.0096668862848084	0.0444664569050057	1.0	0.7412093339623087	6	Q9NVG8,Q8TC07	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7944841561041261	1.9569878603539568	0.0503488956389668	1.0	0.7412093339623087	5	P27544,Q96CP7,Q96G23	3
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.7929665941327556	1.950400114424091	0.0511284482409037	1.0	0.7412093339623087	5	Q99536,Q8N4Q0	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7475235734486776	1.908819481735053	0.0562853827920364	1.0	0.7412093339623087	6	Q99536,Q8N4Q0	2
+Death domain [IPR000488]	0.878278537940723	1.7420835062746445	0.0814938332462484	1.0	0.7412093339623087	3	Q13546	1
+MHC class I-like antigen recognition-like [IPR011161]	0.8596006144393228	1.6683443273915957	0.0952473931279165	1.0	0.7412093339623087	3	P01889,P10321	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8596006144393228	1.6683443273915957	0.0952473931279165	1.0	0.7412093339623087	3	P01889,P10321	2
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8596006144393228	1.6683443273915957	0.0952473931279165	1.0	0.7412093339623087	3	P01889,P10321	2
+Immunoglobulin C1-set [IPR003597]	0.8596006144393228	1.6683443273915957	0.0952473931279165	1.0	0.7412093339623087	3	P01889,P10321	2
+Zinc finger, CHHC-type [IPR012996]	0.8531490015360967	1.642799795160355	0.1004243626143877	1.0	0.7412093339623087	3	P31943,P52597	2
+PurM-like, C-terminal domain [IPR010918]	0.8454388879897126	1.6122265753878475	0.1069126442774186	1.0	0.7412093339623087	3	P49903	1
+CS domain [IPR007052]	0.6834138392385487	1.5973837493490797	0.1101801926072756	1.0	0.7412093339623087	7	Q9Y266,Q9UHD1,Q96RS6	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.6795570620299047	1.5967203874893403	0.110328049025232	1.0	0.7412093339623087	6	Q9BUF5,Q9BVA1,P07437	3
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.6795570620299047	1.5967203874893403	0.110328049025232	1.0	0.7412093339623087	6	Q9BUF5,Q9BVA1,P07437	3
+CTLH, C-terminal LisH motif [IPR006595]	0.7416274585427453	1.5753571296681417	0.1151740339719062	1.0	0.7412093339623087	4	Q9UL63	1
+Beta-adaptin appendage, C-terminal subdomain [IPR015151]	0.8269596564172079	1.538767460742064	0.1238610763580108	1.0	0.7412093339623087	3	Q10567	1
+Rhodanese-like domain [IPR001763]	0.7329377956738204	1.5378953841902403	0.1240741960872366	1.0	0.7412093339623087	4	Q99956,P25325	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7316469994431769	1.5323243513017142	0.1254424148533353	1.0	0.7412093339623087	4	O15460,P13674	2
+Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]	0.7264904732636767	1.5100535560456676	0.1310297590537392	1.0	0.7412093339623087	4	Q9NSV4,O60610,Q9Y613	3
+Formin, FH2 domain [IPR015425]	0.7264904732636767	1.5100535560456676	0.1310297590537392	1.0	0.7412093339623087	4	Q9NSV4,O60610,Q9Y613	3
+FAD dependent oxidoreductase [IPR006076]	0.72215705535552	1.491319515054222	0.1358776277302715	1.0	0.7412093339623087	4	Q9H9P8,Q96CU9	2
+Reticulon [IPR003388]	0.8090644027907937	1.467425438442605	0.1422603586209612	1.0	0.7412093339623087	3	Q16799	1
+Peptidase S9A, N-terminal domain [IPR023302]	0.9781941031941044	1.429308422459159	0.1529156062867871	1.0	0.7615787479925804	2	P48147	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.7964256429324934	1.4169490860190488	0.1564978137202919	1.0	0.7640515603027053	3	Q9ULX6	1
+Heat shock chaperonin-binding [IPR006636]	0.6694768062762733	1.4020034084856066	0.1609142288657872	1.0	0.7676217448929612	5	Q9NRR5	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.968980343980345	1.3947360631480314	0.1630954456144793	1.0	0.7676217448929612	2	O75431	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.968980343980345	1.3947360631480314	0.1630954456144793	1.0	0.7676217448929612	2	O75431	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6508501500603757	1.3946065112537611	0.1631345305134641	1.0	0.7676217448929612	10	O95302,Q14318,Q9Y680,Q9NWM8	4
+PTB/PI domain [IPR006020]	0.6579831453610359	1.3500173826831028	0.1770104071551179	1.0	0.7818535054947253	5	O00213,Q9Y3P9,Q8NEU8	3
+Mad3/Bub1 homology region 1 [IPR013212]	0.9527027027027029	1.3337116250698902	0.1822983834316458	1.0	0.7818535054947253	2	O43683	1
+TGS [IPR004095]	0.6213698119843893	1.3236899247919167	0.1856060459283652	1.0	0.7818535054947253	6	Q9BW92	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7724854609979381	1.3212251543177795	0.1864263013923304	1.0	0.7818535054947253	3	P51114	1
+Agenet-like domain [IPR008395]	0.7724854609979381	1.3212251543177795	0.1864263013923304	1.0	0.7818535054947253	3	P51114	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7724854609979381	1.3212251543177795	0.1864263013923304	1.0	0.7818535054947253	3	P51114	1
+Fxr1, tudor domain [IPR041560]	0.7724854609979381	1.3212251543177795	0.1864263013923304	1.0	0.7818535054947253	3	P51114	1
+Glycosyl transferase, family 1 [IPR001296]	0.7702334074038708	1.31221784895546	0.1894466411462367	1.0	0.785104889013558	3	Q2TAA5	1
+Kinesin motor domain [IPR001752]	0.6387503168317316	1.3057300353905608	0.1916443801117648	1.0	0.7877996941068285	12	O95239,Q15058,Q9Y496,Q99661,Q96Q89,Q9BW19	6
+Rho GTPase-activating protein domain [IPR000198]	0.6740115660962025	1.2823830989643592	0.1997082900357971	1.0	0.7880938926909717	4	Q9H0H5,Q68EM7	2
+SPRY-associated [IPR006574]	0.6634116402438808	1.2362901737883811	0.2163507222991847	1.0	0.7923390887603565	4	Q14258,P19474	2
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.9216830466830483	1.2177835771329204	0.2233062267972814	1.0	0.7967903693009608	2	P13674	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6045713935892179	1.208226657944241	0.2269600904698792	1.0	0.8001099722698142	8	P08183	1
+Arf GTPase activating protein [IPR001164]	0.7417089676706783	1.1982150645160226	0.2308333021760247	1.0	0.8030018342986573	3	Q8IYB5	1
+SUN domain [IPR012919]	0.7413210445468473	1.1966667212434532	0.2314364830608606	1.0	0.8030018342986573	3	O94901,Q9UH99	2
+Ubiquitin-associated domain [IPR015940]	0.6158393264414131	1.1807210994383202	0.2377135367520035	1.0	0.809311863766106	13	Q9NRR5,Q04323,Q9UHD9	3
+HR1 rho-binding domain [IPR011072]	0.7327188940092128	1.1623555066139248	0.2450910885096049	1.0	0.8208533288896669	3	Q13464,Q16513	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.7308874695311132	1.1550569442826064	0.2480671082113619	1.0	0.8239817011442725	3	Q9UL46	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.7308874695311132	1.1550569442826064	0.2480671082113619	1.0	0.8239817011442725	3	Q9UL46	1
+ADCK3-like domain [IPR034646]	0.902334152334156	1.145870408656947	0.2518487768188944	1.0	0.827198718421243	2	Q96D53	1
+ABC1 atypical kinase-like domain [IPR004147]	0.902334152334156	1.145870408656947	0.2518487768188944	1.0	0.827198718421243	2	Q96D53	1
+Formin, GTPase-binding domain [IPR010473]	0.7262672811059867	1.136656174815202	0.255682046769806	1.0	0.832541048841585	3	Q9NSV4,O60610	2
+Formin, FH3 domain [IPR010472]	0.7262672811059867	1.136656174815202	0.255682046769806	1.0	0.832541048841585	3	Q9NSV4,O60610	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5818212744722285	1.1180510416163758	0.2635451944682434	1.0	0.8446613365186543	7	O15460,P13674	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5818212744722285	1.1180510416163758	0.2635451944682434	1.0	0.8446613365186543	7	O15460,P13674	2
+LEM domain [IPR003887]	0.5753022978051137	1.1056126850784918	0.2688941969475635	1.0	0.8446613365186543	6	Q86XL3,P42166	2
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.8891277641277677	1.0970381184825462	0.272624729236703	1.0	0.8446613365186543	2	O15027	1
+Ataxin-2, C-terminal [IPR009818]	0.7154304789343024	1.0935718416254092	0.2741428045841814	1.0	0.8446613365186543	3	Q8WWM7	1
+Potentiating neddylation domain [IPR005176]	0.8845208845208863	1.0800609931973757	0.2801150203745175	1.0	0.8458680434174651	2	Q96GG9	1
+Tankyrase 1-binding protein, C-terminal [IPR032764]	0.884213759213762	1.078930330178124	0.2806187867886924	1.0	0.8458680434174651	2	Q9C0C2	1
+RQC domain [IPR018982]	0.7093701996927756	1.0695321041659005	0.2848299706458732	1.0	0.8499756988015101	3	Q14191,P46063	2
+ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]	0.7093701996927756	1.0695321041659005	0.2848299706458732	1.0	0.8499756988015101	3	Q14191,P46063	2
+Butyrophylin-like, SPRY domain [IPR003879]	0.5901522968340601	1.0426770543300945	0.2970978885096325	1.0	0.8767040370752994	5	Q14258,P19474	2
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.8703931203931232	1.0282113113550573	0.3038504387653646	1.0	0.8867335100393202	2	Q15120	1
+Histidine kinase domain [IPR005467]	0.8703931203931232	1.0282113113550573	0.3038504387653646	1.0	0.8867335100393202	2	Q15120	1
+Threonyl/alanyl tRNA synthetase, SAD [IPR012947]	0.5844755314370439	1.0170615397791316	0.309124154917638	1.0	0.8951926057142351	5	Q9BW92	1
+B-box, C-terminal [IPR003649]	0.6109549498954921	1.0089863174959637	0.3129811961700928	1.0	0.8952247749267409	4	Q9UPN9	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8574938574938613	0.9811912677699312	0.3264984295249307	1.0	0.8952247749267409	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8574938574938613	0.9811912677699312	0.3264984295249307	1.0	0.8952247749267409	2	Q9Y282	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8547297297297356	0.9711603068457844	0.3314684565040122	1.0	0.8979534825784922	2	Q8N2A8	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.5674913030114819	0.940706048934469	0.3468555182935517	1.0	0.9127273571191808	5	Q9HD20	1
+GYF domain [IPR003169]	0.8381449631449676	0.911348476947592	0.3621117916620322	1.0	0.9256324501469794	2	Q6Y7W6	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.5789370932345919	0.8721553229044812	0.383123648788185	1.0	0.9334461498949388	4	P08670,P07196	2
+Intermediate filament, rod domain [IPR039008]	0.5324463511794509	0.8668588225190058	0.3860193676314014	1.0	0.9334461498949388	8	P08670,P48681,P07196	3
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8200245700245744	0.8468346215812631	0.397087307651552	1.0	0.9362878522886072	2	Q92945	1
+Tudor domain [IPR002999]	0.5314428281077613	0.8445131995855295	0.3983826905539649	1.0	0.9362878522886072	9	Q9Y2W6,Q92667,Q16637	3
+Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]	0.6423767395322415	0.8082370132252742	0.4189541541659256	1.0	0.9527415169600988	3	Q13310	1
+BSD domain [IPR005607]	0.807739557739565	0.8036754866398003	0.4215844148222563	1.0	0.9543400623202446	2	Q9NW68	1
+LIS1 homology motif [IPR006594]	0.5219389164610375	0.8002026115897243	0.4235934169488211	1.0	0.9555198986755346	9	Q9UL63,O95684	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.8015970515970592	0.7822922346906526	0.4340428494104213	1.0	0.958737923008483	2	O95140	1
+SET domain [IPR001214]	0.5171166932270972	0.7778326166214958	0.4366676967988538	1.0	0.9592788877600928	9	Q15910,Q15047,O15047,Q9H7B4,Q96L73	5
+RING-type zinc-finger, LisH dimerisation motif [IPR027370]	0.7997542997542995	0.7759043563485718	0.437805460245747	1.0	0.9592788877600928	2	Q9UPN9	1
+THIF-type NAD/FAD binding fold [IPR000594]	0.5080925731927821	0.7718041336450061	0.4402304431153445	1.0	0.9592788877600928	7	A0AVT1,Q9UBE0	2
+BAT2, N-terminal [IPR009738]	0.7890049140049173	0.7389048969596719	0.4599647485649722	1.0	0.9737097811832564	2	Q9Y520	1
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.7886977886977874	0.7378546170391839	0.4606027996126909	1.0	0.9737097811832564	2	Q9NSV4	1
+Zinc finger, GRF-type [IPR010666]	0.7816339066339131	0.7138085787863757	0.4753455541864604	1.0	0.9775405042796268	2	Q13472	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.773341523341526	0.6858623708591748	0.4927999009322834	1.0	0.980085450371876	2	P51114	1
+RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]	0.7690417690417671	0.6714979371106401	0.5019033731861984	1.0	0.9802897904538086	2	O43347	1
+RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]	0.7690417690417671	0.6714979371106401	0.5019033731861984	1.0	0.9802897904538086	2	O43347	1
+AWS domain [IPR006560]	0.6039938556067522	0.6647557200331378	0.5062067485510595	1.0	0.9802897904538086	3	O96028,Q96L73	2
+STAT transcription factor, all-alpha domain [IPR013800]	0.7662776412776505	0.662311008180514	0.507771923348832	1.0	0.9802897904538086	2	P40763	1
+STAT transcription factor, protein interaction [IPR013799]	0.7662776412776505	0.662311008180514	0.507771923348832	1.0	0.9802897904538086	2	P40763	1
+STAT transcription factor, DNA-binding [IPR013801]	0.7662776412776505	0.662311008180514	0.507771923348832	1.0	0.9802897904538086	2	P40763	1
+AGC-kinase, C-terminal [IPR000961]	0.4906222062949545	0.6566443278669336	0.5114096391504253	1.0	0.9802897904538086	9	Q16513,Q96GX5,P31751,Q13464,P51812	5
+tRNA/rRNA methyltransferase, SpoU type [IPR001537]	0.7632063882063937	0.6521479050743163	0.5143057628071082	1.0	0.9802897904538086	2	Q9HC36	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.7625921375921423	0.6501210096447829	0.5156140591449083	1.0	0.9802897904538086	2	Q5T9A4	1
+Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]	0.7585995085995103	0.6369936047817446	0.5241290092664013	1.0	0.9802897904538086	2	P46926	1
+Pre-PUA domain [IPR041366]	0.7573710073710177	0.6329711776967241	0.5267524649170812	1.0	0.9802897904538086	2	Q9ULC4	1
+HECT domain [IPR000569]	0.479803485500513	0.6254856846540169	0.5316523409931873	1.0	0.9802897904538086	8	Q05086	1
+Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]	0.4700709347963878	0.6180417751907351	0.5365478014557987	1.0	0.98176282058757	6	Q10567	1
+Peptidase M16, middle/third domain [IPR032632]	0.752764127764139	0.6179590873583896	0.536602307894817	1.0	0.98176282058757	2	O43847	1
+SUN coiled coil domain 2 [IPR040994]	0.7444717444717475	0.5912337484367628	0.5543638131634108	1.0	0.9826622089397729	2	Q9UH99	1
+Iron-binding zinc finger, CDGSH type [IPR018967]	0.7429361179361245	0.5863278771677567	0.5576552008839712	1.0	0.9826622089397729	2	Q9NZ45	1
+Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]	0.7429361179361245	0.5863278771677567	0.5576552008839712	1.0	0.9826622089397729	2	Q9NZ45	1
+Post-SET domain [IPR003616]	0.4621633985518616	0.5832162495790078	0.5597477335380687	1.0	0.9826622089397729	6	O96028,O15047,Q15047,Q96L73	4
+LEM-like domain [IPR013146]	0.7374078624078735	0.5687827113021229	0.5695036087738001	1.0	0.9863604623561878	2	P42166	1
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.4636999453819803	0.5545309427350412	0.5792155352839741	1.0	0.9879278122982956	8	Q13464,Q9H0H5,Q92974	3
+ROCK, Rho binding domain [IPR015008]	0.7324938574938551	0.5533435648168926	0.5800281751896081	1.0	0.9879278122982956	2	Q13464	1
+WH2 domain [IPR003124]	0.7260442260442361	0.5333117737915751	0.5938177788202097	1.0	0.988490655295422	2	Q9Y6W5	1
+Dbl homology (DH) domain [IPR000219]	0.4669071275500464	0.5092275357378342	0.6105927442702366	1.0	0.9913819926985772	5	Q6XZF7	1
+K Homology domain, type 1 [IPR004088]	0.4988057367082113	0.5055932030537704	0.6131422540835643	1.0	0.9926681396168	22	P61978,P51116,Q9UNW9,P51114,Q92667,Q96AE4,Q15365,Q92945,Q9Y2W6	9
+SH2 domain [IPR000980]	0.45830756049464	0.4977977489460728	0.618626602727306	1.0	0.9937112622181028	10	Q06124,P42224,P40763,P46109	4
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4572048168407289	0.4930984053409076	0.6219430575734579	1.0	0.994000381553352	10	P49748,Q15067	2
+Gelsolin-like domain [IPR007123]	0.4345018450184542	0.4651278222242052	0.6418399229271254	1.0	1.0	6	P53992,Q13045,O94855,Q15436,O95487	5
+Cold-shock protein, DNA-binding [IPR002059]	0.5440860215053688	0.4570523461628277	0.6476334211765753	1.0	1.0	3	O75534,P67809	2
+Cold shock domain [IPR011129]	0.5440860215053688	0.4570523461628277	0.6476334211765753	1.0	1.0	3	O75534,P67809	2
+Cold-shock (CSD) domain [IPR019844]	0.5440860215053688	0.4570523461628277	0.6476334211765753	1.0	1.0	3	O75534,P67809	2
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4717271051014163	0.4460276658276956	0.655577261716018	1.0	1.0	4	O00487,P51665,O00303	3
+Serpin domain [IPR023796]	0.5400921658986099	0.4441450223840895	0.6569377374980898	1.0	1.0	3	P30740,P50454	2
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6931818181818182	0.4357339700330143	0.6630297560910703	1.0	1.0	2	P13861	1
+Zinc-finger CCCH domain [IPR041686]	0.6919533169533277	0.4322436390953618	0.6655643454881288	1.0	1.0	2	O95639	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.46614042827939	0.4261306528327829	0.6700126453862045	1.0	1.0	4	Q9H3P7	1
+L27 domain, C-terminal [IPR014775]	0.441613601212119	0.4113008608488439	0.6808519384386722	1.0	1.0	5	Q14168	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4425669703983765	0.4008635295740133	0.6885206023761357	1.0	1.0	12	P08183	1
+Exosome complex component, N-terminal domain [IPR025721]	0.6793611793611789	0.3971787597181731	0.6912356440537408	1.0	1.0	2	Q9Y3B2	1
+GRAM domain [IPR004182]	0.6787469287469365	0.3955022263133005	0.6924722789132225	1.0	1.0	2	Q969T9	1
+WW domain [IPR001202]	0.4552298457022656	0.3951551854445005	0.6927283637544983	1.0	1.0	16	Q96J02,O00213,Q6ZWJ1,O95817	4
+B-box-type zinc finger [IPR000315]	0.4203539830814007	0.3906879856979962	0.6960278804948432	1.0	1.0	7	Q9UPN9,P19474	2
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.4551461974164306	0.3879277325007095	0.6980695145345877	1.0	1.0	4	Q06124	1
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.4551461974164306	0.3879277325007095	0.6980695145345877	1.0	1.0	4	Q06124	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.4343682754380731	0.3844647587936743	0.7006340109369422	1.0	1.0	5	Q15436,P53992,O95487,O94855	4
+Sec23/Sec24, helical domain [IPR006900]	0.4343682754380731	0.3844647587936743	0.7006340109369422	1.0	1.0	5	Q15436,P53992,O95487,O94855	4
+Sec23/Sec24, trunk domain [IPR006896]	0.4343682754380731	0.3844647587936743	0.7006340109369422	1.0	1.0	5	Q15436,P53992,O95487,O94855	4
+Sec23/Sec24 beta-sandwich [IPR012990]	0.4343682754380731	0.3844647587936743	0.7006340109369422	1.0	1.0	5	Q15436,P53992,O95487,O94855	4
+DNA mismatch repair protein MutS, core [IPR007696]	0.5179012450013574	0.3750617389582691	0.7076145512938572	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.5179012450013574	0.3750617389582691	0.7076145512938572	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.5179012450013574	0.3750617389582691	0.7076145512938572	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.5179012450013574	0.3750617389582691	0.7076145512938572	1.0	1.0	3	P43246	1
+K Homology domain [IPR004087]	0.4677704602856521	0.3711091018176329	0.7105562720702645	1.0	1.0	22	P61978,P51116,Q9UNW9,P51114,Q96I24,Q92667,Q96AE4,Q15365,Q92945,Q9Y2W6,Q15366	11
+Glutamine amidotransferase [IPR017926]	0.4480639213275998	0.364029351927127	0.7158360912648338	1.0	1.0	4	P17812,P49915,Q9NRF8	3
+Amidohydrolase-related [IPR006680]	0.4480639213275998	0.364029351927127	0.7158360912648338	1.0	1.0	4	Q9BPU6,Q16555,Q14195	3
+EF-hand, Ca insensitive [IPR014837]	0.5084485407065968	0.34709722041639	0.7285182816361857	1.0	1.0	3	P12814,O43707	2
+Sec24-like, trunk domain [IPR041742]	0.4342347879532911	0.3190981680740621	0.7496520727740092	1.0	1.0	4	P53992,O95487,O94855	3
+Sterile alpha motif domain [IPR001660]	0.4217872556870148	0.3189263947789579	0.7497823285186125	1.0	1.0	12	Q9Y6Y8,Q9P246,Q5PRF9,Q6SZW1,Q92625,Q9Y3Z3	6
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.4323340743468539	0.313111245568376	0.7541961456465296	1.0	1.0	4	P51784,Q8NFA0	2
+NSD, Cys-His rich domain [IPR041306]	0.6464987714987727	0.312239480681602	0.754858529640924	1.0	1.0	2	Q96L73	1
+DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]	0.4929100157979326	0.30320916274976	0.7617304666440119	1.0	1.0	3	P49005	1
+GAR domain [IPR003108]	0.6250000000000041	0.2622998647777081	0.7930902662682269	1.0	1.0	2	Q03001	1
+BAR domain [IPR004148]	0.4152629388316723	0.2615228426941551	0.7936893363665449	1.0	1.0	4	Q6XZF7,Q68EM7	2
+SUI1 domain [IPR001950]	0.6228501228501278	0.2575665318384738	0.7967414620880158	1.0	1.0	2	P41214	1
+CTP synthase GATase domain [IPR033828]	0.6216216216216262	0.2548835316858474	0.7988130560936864	1.0	1.0	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.6216216216216262	0.2548835316858474	0.7988130560936864	1.0	1.0	2	Q9NRF8	1
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.6207002457002502	0.252881704211601	0.8003596279869376	1.0	1.0	2	Q9NP81	1
+Zinc finger, RanBP2-type [IPR001876]	0.3915050784856934	0.2517143130608598	0.8012618929287809	1.0	1.0	9	P98175,P49790,P35637,Q8TAT6,P49792,O95218,Q01844,P52756	8
+La-type HTH domain [IPR006630]	0.3882440748884492	0.2293908305256206	0.8185651623574128	1.0	1.0	5	Q6PKG0	1
+SCP2 sterol-binding domain [IPR003033]	0.4599078341013731	0.2194235580452347	0.8263201204742736	1.0	1.0	3	P22307,P51659	2
+DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]	0.4586789554531396	0.2165682742933439	0.828544812387229	1.0	1.0	3	P09884,P28340	2
+DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]	0.4586789554531396	0.2165682742933439	0.828544812387229	1.0	1.0	3	P09884,P28340	2
+Nuclear transport factor 2 domain [IPR002075]	0.3899815611555038	0.1929132742173323	0.8470268889849055	1.0	1.0	4	Q13283,P61970,Q9UN86	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3899815611555038	0.1929132742173323	0.8470268889849055	1.0	1.0	4	Q13283,P61970,Q9UN86	3
+U-box domain [IPR003613]	0.3605288593156908	0.1920459367477674	0.8477062227476411	1.0	1.0	6	P19474	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.5850737100737167	0.1825017278326995	0.8551889985152807	1.0	1.0	2	Q9BSJ2	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.5850737100737167	0.1825017278326995	0.8551889985152807	1.0	1.0	2	Q9BSJ2	1
+Protein kinase, C-terminal [IPR017892]	0.3571893653881996	0.1816789279365621	0.8558347038153653	1.0	1.0	6	P31751,P51812	2
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.5687960687960762	0.1550081168594953	0.8768149183240133	1.0	1.0	2	O43747	1
+EB1, C-terminal [IPR004953]	0.5672604422604497	0.1525669239706651	0.8787398104214781	1.0	1.0	2	Q15555	1
+Cyclin-like [IPR013763]	0.3599754073163336	0.1504197763795005	0.8804334394852007	1.0	1.0	5	P14635,O95067,P06400,O75909	4
+Dynamin, N-terminal [IPR045063]	0.3544138026056809	0.1465032526209705	0.8835241224037795	1.0	1.0	8	O95140,O00429,Q8IWA4	3
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.3544138026056809	0.1465032526209705	0.8835241224037795	1.0	1.0	8	O95140,O00429,Q8IWA4	3
+Domain of unknown function DUF1899 [IPR015048]	0.4172043010752589	0.1321230320344568	0.8948869786805653	1.0	1.0	3	Q9ULV4,P57737	2
+Cyclin, N-terminal [IPR006671]	0.35986478180701	0.1244964021500988	0.900922248887884	1.0	1.0	4	O95067,P14635,O75909	3
+Cyclin, C-terminal domain [IPR004367]	0.35986478180701	0.1244964021500988	0.900922248887884	1.0	1.0	4	O95067,P14635,O75909	3
+HDGF-related, PWWP domain [IPR035496]	0.4115749900891368	0.12248590071752	0.9025142115109366	1.0	1.0	3	O75475	1
+Actin-depolymerising factor homology domain [IPR002108]	0.3458461538461462	0.1223224943209171	0.9026436178774392	1.0	1.0	8	Q14019,Q16643,P60981,Q9UJU6,Q12792,P60983,Q9Y281	7
+WHEP-TRS domain [IPR000738]	0.3586355255070714	0.1220256921815525	0.9028786708981114	1.0	1.0	4	P07814,P23381,P56192	3
+SPRY domain [IPR003877]	0.3568447525077364	0.1161338581215633	0.9075464554524884	1.0	1.0	11	Q96S59,Q14258	2
+B30.2/SPRY domain [IPR001870]	0.3568447525077364	0.1161338581215633	0.9075464554524884	1.0	1.0	11	Q96S59,Q14258	2
+RAP domain [IPR013584]	0.4058371735791001	0.1131151106800997	0.9099392952904684	1.0	1.0	3	Q7L8L6,Q9NYY8	2
+FAST kinase leucine-rich [IPR010622]	0.4058371735791001	0.1131151106800997	0.9099392952904684	1.0	1.0	3	Q7L8L6,Q9NYY8	2
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.4058371735791001	0.1131151106800997	0.9099392952904684	1.0	1.0	3	Q7L8L6,Q9NYY8	2
+YTH domain [IPR007275]	0.4024577572964565	0.107808885802707	0.9141472941251672	1.0	1.0	3	Q9Y5A9,Q9H6S0	2
+FFD box [IPR025761]	0.5328624078624145	0.1047009007592592	0.9166131471897794	1.0	1.0	2	Q8ND56	1
+TFG box [IPR025768]	0.5328624078624145	0.1047009007592592	0.9166131471897794	1.0	1.0	2	Q8ND56	1
+Methyl-CpG DNA binding [IPR001739]	0.3444250972558254	0.0953225737224078	0.924058613054451	1.0	1.0	4	Q9UIF9	1
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.3288219009535487	0.0900972301588745	0.928209950282538	1.0	1.0	7	P25789,P25788,P25786,P60900,P25787,O14818	6
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.3326989746019416	0.0880088318628175	0.9298696565718272	1.0	1.0	8	P49748	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.3326989746019416	0.0880088318628175	0.9298696565718272	1.0	1.0	8	P49748	1
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.5144348894348967	0.0842640654544818	0.9328464823694568	1.0	1.0	2	Q5VWZ2	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5138206388206428	0.0836425594068786	0.9333406279610544	1.0	1.0	2	Q9BSJ8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5138206388206428	0.0836425594068786	0.9333406279610544	1.0	1.0	2	Q9BSJ8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5138206388206428	0.0836425594068786	0.9333406279610544	1.0	1.0	2	Q9BSJ8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5138206388206428	0.0836425594068786	0.9333406279610544	1.0	1.0	2	Q9BSJ8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5138206388206428	0.0836425594068786	0.9333406279610544	1.0	1.0	2	Q9BSJ8	1
+OCRE domain [IPR041591]	0.385560675883248	0.0836196867991858	0.9333588139523544	1.0	1.0	3	P98175,P52756	2
+CARG-binding factor, N-terminal [IPR012956]	0.5052211302211365	0.0753327463035584	0.9399499677146994	1.0	1.0	2	Q14103	1
+PITH domain [IPR010400]	0.5046068796068857	0.0747667625527093	0.940400287412603	1.0	1.0	2	O43396	1
+14-3-3 domain [IPR023410]	0.3170356703567107	0.0736059857113876	0.941323908152958	1.0	1.0	6	P27348,P61981,P63104,Q04917,P62258	5
+Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]	0.4996928746928806	0.0703685499611059	0.9439003226715554	1.0	1.0	2	Q9Y6A5	1
+Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]	0.4984643734643825	0.0693046379922814	0.944747134032846	1.0	1.0	2	P07814	1
+Domain of unknown function DUF3517 [IPR021905]	0.496007371007383	0.0672189969524749	0.9464073619463458	1.0	1.0	2	Q9UPU5	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.3136843701347875	0.0660420915129719	0.9473443144010908	1.0	1.0	6	Q99956,Q06124	2
+SANT domain [IPR017884]	0.3266120919130227	0.0622637763897201	0.950352774735818	1.0	1.0	9	Q92922	1
+Zinc finger, CCHC-type [IPR001878]	0.3213121052273227	0.0611046316236426	0.9512758805436456	1.0	1.0	8	O95639,Q8TBF4,Q9BWF3,Q6NZY4	4
+Radical SAM [IPR007197]	0.366513056835628	0.0608994695676078	0.9514392718872992	1.0	1.0	3	Q5VV42,Q9NZB8	2
+Elp3/MiaB/NifB [IPR006638]	0.366513056835628	0.0608994695676078	0.9514392718872992	1.0	1.0	3	Q5VV42,Q9NZB8	2
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.3141715339686565	0.052890237955125	0.9578193624940636	1.0	1.0	5	Q9UHD8,Q14141,Q9UH03,Q16181	4
+NOPS [IPR012975]	0.357296466973877	0.0515531030497206	0.9588847879582048	1.0	1.0	3	Q8WXF1,Q15233	2
+Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]	0.4674447174447219	0.0468669506666318	0.9626192686835248	1.0	1.0	2	P26599	1
+Aminopeptidase P, N-terminal [IPR007865]	0.4637592137592178	0.044727197560377	0.9643247548683088	1.0	1.0	2	Q9NQH7	1
+Domain of unknown function DUF4749 [IPR031847]	0.4603808353808355	0.042855592331164	0.9658166483891868	1.0	1.0	2	Q96HC4	1
+Zinc finger, RING-type [IPR001841]	0.372760557768362	0.0427350168076889	0.9659127656809738	1.0	1.0	22	Q14258,Q14527,O75150,Q96T51,O15344,Q9UPN9,Q86UK7,P19474,O94822	9
+Myb domain [IPR017930]	0.3113903240053973	0.0398318868311075	0.9682271543812616	1.0	1.0	8	Q92922	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.4527027027027072	0.0389095160693755	0.9689625295894664	1.0	1.0	2	Q9BRX2	1
+eRF1 domain 2 [IPR005141]	0.4527027027027072	0.0389095160693755	0.9689625295894664	1.0	1.0	2	Q9BRX2	1
+eRF1 domain 3 [IPR005142]	0.4527027027027072	0.0389095160693755	0.9689625295894664	1.0	1.0	2	Q9BRX2	1
+Vicinal oxygen chelate (VOC) domain [IPR037523]	0.4523955773955802	0.0387602886816191	0.9690815060670944	1.0	1.0	2	Q9HC38	1
+DnaJ domain [IPR001623]	0.3426550526793183	0.0368058844728443	0.9706397820984268	1.0	1.0	15	Q8WXX5,Q99543	2
+Peptidase S8/S53 domain [IPR000209]	0.4471744471744524	0.0363211042702308	0.9710263222666438	1.0	1.0	2	O14773	1
+ELMO domain [IPR006816]	0.4401105651105638	0.0333039896130143	0.9734321722751004	1.0	1.0	2	Q96JJ3	1
+Signal recognition particle SRP54, helical bundle [IPR013822]	0.4358108108108095	0.0316188352964121	0.9747760225048216	1.0	1.0	2	P08240	1
+Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]	0.4358108108108095	0.0316188352964121	0.9747760225048216	1.0	1.0	2	P08240	1
+RasGAP protein, C-terminal [IPR000593]	0.4293611793611824	0.0292937295625617	0.9766303278420956	1.0	1.0	2	Q13576	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4219901719901822	0.0269161946139605	0.97852657676302	1.0	1.0	2	Q9Y305	1
+Sorting nexin, N-terminal [IPR005329]	0.4216830466830487	0.0268232835082322	0.978600682343472	1.0	1.0	2	Q13596	1
+Jumonji, helical domain [IPR041070]	0.4213759213759262	0.0267308501740012	0.9786744070382738	1.0	1.0	2	Q9Y2K7	1
+IBR domain [IPR002867]	0.4103194103194127	0.0237075709361792	0.9810858669704844	1.0	1.0	2	Q9Y4X5	1
+TRIAD supradomain [IPR044066]	0.4103194103194127	0.0237075709361792	0.9810858669704844	1.0	1.0	2	Q9Y4X5	1
+Ariadne domain [IPR045840]	0.4103194103194127	0.0237075709361792	0.9810858669704844	1.0	1.0	2	Q9Y4X5	1
+HD domain [IPR006674]	0.4060196560196543	0.0226821320402416	0.9819038287359954	1.0	1.0	2	Q9Y3Z3	1
+HD/PDEase domain [IPR003607]	0.4060196560196543	0.0226821320402416	0.9819038287359954	1.0	1.0	2	Q9Y3Z3	1
+GINS subunit, domain A [IPR021151]	0.4017199017198988	0.021734208434992	0.9826599758272072	1.0	1.0	2	Q9BRT9	1
+Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]	0.3119293700383747	0.0210672821773506	0.9831919841398168	1.0	1.0	10	Q10567	1
+FKBP3, basic tilted helix bundle domain [IPR041200]	0.3759213759213726	0.0174445984415041	0.9860819301483172	1.0	1.0	2	Q9ULT8	1
+Nucleotidyl transferase domain [IPR005835]	0.3062980030721872	0.0166563096218437	0.9867108021918476	1.0	1.0	3	Q96IJ6,Q9Y5P6	2
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]	0.3657862407862429	0.0162980206667821	0.9869966366116454	1.0	1.0	2	Q13423	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]	0.3657862407862429	0.0162980206667821	0.9869966366116454	1.0	1.0	2	Q13423	1
+Pleckstrin homology domain [IPR001849]	0.3718440811732559	0.013766824882844	0.9890160099334396	1.0	1.0	25	O14654,Q9BZF1,Q92974,Q9Y5P4,Q8NEU8,Q9BXB4,O75116,P31751,Q96SU4,Q6WCQ1,Q96JJ3,Q13464,Q96TA1	13
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.319717444717439	0.0135143978519642	0.9892173988268608	1.0	1.0	2	P82663	1
+Thioredoxin-like fold [IPR012336]	0.3129606879606811	0.0133262523834786	0.9893675036731944	1.0	1.0	2	Q8NBF2	1
+Glycosyl transferase CAP10 domain [IPR006598]	0.3111179361179364	0.0132812211267687	0.9894034302382222	1.0	1.0	2	Q7Z4H8	1
+THUMP domain [IPR004114]	0.3065110565110522	0.0131791965697858	0.98948482693294	1.0	1.0	2	Q9NXG2	1
+GHMP kinase, C-terminal domain [IPR013750]	0.2982186732186667	0.0130290973485858	0.9896045785017802	1.0	1.0	2	Q03426	1
+GHMP kinase N-terminal domain [IPR006204]	0.2982186732186667	0.0130290973485858	0.9896045785017802	1.0	1.0	2	Q03426	1
+NIPSNAP [IPR012577]	0.2853194103194029	0.012863953481674	0.9897363332010194	1.0	1.0	2	Q9BPW8	1
+Ubiquitin-like domain [IPR000626]	0.3344905182800186	0.0096097554958301	0.992332642467058	1.0	1.0	16	P46379,Q9NRR5	2
+Syntaxin, N-terminal domain [IPR006011]	0.2639827904118046	0.0045022157738826	0.99640776368036	1.0	1.0	4	Q13277,O14662,Q86Y82	3
+Ras GTPase-activating domain [IPR001936]	0.2615242778119271	0.0031063101070433	0.9975215271103894	1.0	1.0	4	Q14C86,P46940,Q13576	3
+Extended PHD (ePHD) domain [IPR034732]	0.2583717357910817	0.0029217164752889	0.9976688108499951	1.0	1.0	3	O94880,Q03164	2