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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Mitophagy 0.780566912383857 2.699345136822414 0.0069476082514208 0.9999377222878112 0.7322130752007788 12 O95140,Q15388,Q96E29,P21796,Q9NS69,Q8IWA4 6
Intraflagellar transport 0.7453441050224157 2.622964161263514 0.008716844135598 0.999994768307069 0.7322130752007788 13 Q9BUF5,Q9BVA1,Q9Y496,Q7Z4L5,Q13885,Q92973,P68371 7
Pink1 prkn mediated mitophagy 0.8131380169955169 2.573647452473523 0.0100632756019087 0.9999992079940436 0.7322130752007788 9 O95140,Q15388,Q96E29,P21796,Q9NS69,Q8IWA4 6
Metabolism of porphyrins 0.8065312191703402 2.542401907908293 0.0110093498619177 0.9999997901320572 0.7322130752007788 9 P09601,P22830,P30519 3
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.692549732186248 2.517465788697705 0.0118202448200368 0.999999932835824 0.7322130752007788 17 Q9BUF5,Q9BVA1,O15212,Q13885,P78371,Q99832,P68371,Q9UHV9,P04350 9
Formation of tubulin folding intermediates by cct tric 0.7196070856060762 2.485330665035435 0.0129431148150929 0.9999999861550573 0.7322130752007788 13 Q9BUF5,Q9BVA1,Q13885,P78371,Q99832,P68371,P04350 7
Nucleotide salvage 0.8263214815798408 2.4673180925395948 0.0136129368630233 0.999999994607456 0.7322130752007788 8 P00813 1
Mitochondrial protein import 0.7242815664926834 2.312625377476713 0.0207432450184128 0.9999999999997734 0.7322130752007788 37 Q9Y584,Q3ZCQ8,Q99595,Q8N4Q1,P06576,O43615,P62072,Q13505,Q15388,O75431,Q10713,P21796,Q9NS69,O60830 14
Mitochondrial calcium ion transport 0.6554272535752459 2.301559167790077 0.0213600450654567 0.9999999999999056 0.7322130752007788 17 P21796,Q10713,P45880,Q8IYU8 4
Formation of atp by chemiosmotic coupling 0.7140831603387996 2.260250934647995 0.0238056812785449 0.9999999999999972 0.7322130752007788 11 P00846,P06576 2
Purine salvage 0.8856339345496608 2.2510291806829223 0.0243836892330029 0.9999999999999988 0.7322130752007788 5 P00813 1
Activation of ampk downstream of nmdars 0.8052288133192267 2.2174639286993685 0.0265914053465265 1.0 0.7322130752007788 7 Q9BUF5,Q9BVA1,Q13885,P68371,P04350 5
Aggrephagy 0.6357531688310651 2.207377991635885 0.0272876626394924 1.0 0.7322130752007788 16 Q9BUF5,Q9BVA1,Q13885,P68371,O43237,P08670 6
Carboxyterminal post translational modifications of tubulin 0.8313937156472507 2.1894749534709934 0.0285623370570116 1.0 0.7322130752007788 6 Q13885,Q9BUF5,Q9BVA1,P68371 4
Gap junction trafficking and regulation 0.6971029860791018 2.171698327332398 0.0298784247879513 1.0 0.7322130752007788 11 Q9BUF5,Q9BVA1,P50570,Q13885,P68371 5
Assembly and cell surface presentation of nmda receptors 0.6921549109830284 2.1457329626602135 0.031894289744857 1.0 0.7322130752007788 11 Q9BUF5,Q14168,Q9BVA1,P07196,Q13885,P68371 6
Transport of connexons to the plasma membrane 0.8542883492161129 2.120631898160847 0.0339527916058592 1.0 0.7322130752007788 5 Q13885,Q9BUF5,Q9BVA1,P68371 4
Gap junction assembly 0.8542883492161129 2.120631898160847 0.0339527916058592 1.0 0.7322130752007788 5 Q13885,Q9BUF5,Q9BVA1,P68371 4
Disassembly of the destruction complex and recruitment of axin to the membrane 0.7026131557855433 2.114901501228004 0.0344383432224397 1.0 0.7322130752007788 10 Q16537,Q13362,P30154,O14641,P48729,P25054 6
Post chaperonin tubulin folding pathway 0.6996795865126619 2.099879267183536 0.0357394629989213 1.0 0.7322130752007788 10 Q13885,Q9BUF5,Q9BVA1,P68371 4
Selective autophagy 0.6752712509636064 2.0950363239215086 0.0361677636026314 1.0 0.7322130752007788 33 O95140,Q9BUF5,P04350,Q9BVA1,P50542,Q15388,Q13885,Q96E29,P68371,O43237,P21796,Q9NS69,P08670,Q8IWA4 14
Kinesins 0.6310347213255665 2.090960627744352 0.0365315935312586 1.0 0.7322130752007788 20 Q9BUF5,Q07866,Q9H0B6,Q9BVA1,Q9Y496,Q13885,Q9BW19,P68371,O95239,P04350 10
Class i peroxisomal membrane protein import 0.6669426849840937 2.0123152728314295 0.0441867134757012 1.0 0.7322130752007788 11 P40855,Q9Y3D6,P51648,O43808,Q9NR77,Q9Y5Y5 6
Cell cycle 0.29547481847718 2.0117583733563373 0.0442454139229506 1.0 0.7322130752007788 303 Q68CZ6,P11802,Q9BUF5,Q8WUX9,Q15003,O95684,Q96CS2,Q16537,P61163,P31350,Q08379,Q04917,Q13362,O60763,P30154,P49721,Q96EE3,P15927,P49005,Q8NFH5,Q13885,P33993,Q9UQE7,O94927,P41440,P57740,P31751,Q9BSJ2,Q96DE5,Q14203,P40937,Q9UQ84,Q9H6D7,P12270,O75419,P28070,Q86XL3,O43633,Q99436,P37198,Q9UJX5,Q9UJX3,Q9BRT9,P41208,Q8NBT2,P07437,P42166,P28072,Q9Y6D9,O00231,O75935,P20700,Q92973,Q14191,Q9UH99,Q00534,Q9BTX1,Q9Y619,Q9UL46,Q7Z4H7,P02545,P04350,Q9BVA1,Q13472,Q01105,P56282,Q06323,Q8N1F7,Q15154,P61289,P24941,P68371,O43237,P50402,Q14566,P62258 76
Striated muscle contraction 0.8223178604365265 1.985830015898607 0.0470522016691017 1.0 0.7322130752007788 5 P06753,Q9NYL9,P08670,P67936 4
Transcriptional regulation by ventx 0.6456049233834097 1.9839057392407309 0.0472663490061855 1.0 0.7322130752007788 12 P04637,Q9H1A4,Q96DE5,Q9HCE1,Q9UJX4,Q9UJX5,Q9UJX3 7
Beta catenin phosphorylation cascade 0.6920732675096997 1.982744265079748 0.0473960024515351 1.0 0.7322130752007788 9 Q16537,Q13362,P30154,P48729,P25054 5
Signaling by ctnnb1 phospho site mutants 0.6920732675096997 1.982744265079748 0.0473960024515351 1.0 0.7322130752007788 9 Q16537,Q13362,P30154,P48729,P25054 5
Sealing of the nuclear envelope ne by escrt iii 0.6562908201174413 1.9553962212494216 0.0505363217968188 1.0 0.7322130752007788 11 Q9BUF5,Q8WUX9,Q9BVA1,Q13885,P68371,P04350 6
Cristae formation 0.612407835977205 1.9353909052552416 0.0529423445148384 1.0 0.7322130752007788 22 O75964,Q13505,P00846,P06576 4
Epha mediated growth cone collapse 0.6800486380936094 1.9219652736963977 0.0546101274655064 1.0 0.7322130752007788 9 Q13464,P35580,Q7Z406,P35579,P60660,Q15375 6
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.628842935606475 1.8910870857556452 0.0586127201447463 1.0 0.7680478139721957 12 P09601,P46379,P51648 3
Nephrin family interactions 0.7239214727837301 1.8452767978289255 0.0649972838551296 1.0 0.8095477095065108 7 Q01082,P12814,Q13813 3
Interleukin 4 and interleukin 13 signaling 0.6199887931929541 1.841723673072157 0.0655155796223283 1.0 0.8095477095065108 12 P09601,P08670 2
O linked glycosylation 0.7851357448515394 1.8268665147939784 0.0677198420157503 1.0 0.8131473540743867 5 Q8NAT1,Q10472 2
Synthesis of pa 0.6823376104152832 1.7855384746022775 0.0741740164083353 1.0 0.8279311798853303 8 Q9NPH0 1
Apc c cdc20 mediated degradation of cyclin b 0.6233601903965603 1.777439182919038 0.0754960087871015 1.0 0.8279311798853303 11 Q9UJX3,Q9H1A4,Q96DE5,Q9UJX5,P06493 5
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6515583938189629 1.7765534026826435 0.0756417481273366 1.0 0.8279311798853303 9 Q96DE5,Q9UJX3,Q9H1A4,Q9UJX5 4
Sema4d induced cell migration and growth cone collapse 0.7055120296042775 1.7591324596649984 0.0785550127360954 1.0 0.8279311798853303 7 Q13464,P35580,Q7Z406,P35579,P60660 5
Ctla4 inhibitory signaling 0.6756193899857933 1.7525759841925737 0.0796748165871981 1.0 0.8279311798853303 8 P31751,Q13362,P30154,Q16537 4
Apoptotic cleavage of cellular proteins 0.5677887327742904 1.7263063542400932 0.0842923128159296 1.0 0.8413554759111179 19 P02545,Q9P289,Q13464,Q13813,P20700,Q16625,P08670 7
Release of apoptotic factors from the mitochondria 0.9180562058021892 1.7188680331328268 0.0856384040741755 1.0 0.8413554759111179 3 O60443 1
Cholesterol biosynthesis 0.5589509817877859 1.7163319436378603 0.0861013049382415 1.0 0.8413554759111179 17 Q9BWD1,Q15392,Q16850 3
Platelet sensitization by ldl 0.6948903683347513 1.709143486315195 0.087424374099799 1.0 0.8413554759111179 7 Q16539,Q13362,P30154,Q16537 4
Sphingolipid de novo biosynthesis 0.5927511259702755 1.6884932330938112 0.0913165868593535 1.0 0.8413554759111179 12 P27544,P51648,Q9Y5P4 3
Heme degradation 0.909543405152406 1.686435925913367 0.0917118666450331 1.0 0.8413554759111179 3 P09601 1
Regulation of tp53 expression and degradation 0.6176964260060931 1.6708587587746215 0.0947495791700485 1.0 0.8413554759111179 10 P31751,Q13362,P30153,P30154,P24941,P06493 6
Intra golgi traffic 0.5551145636651194 1.6697084898341594 0.0949770532069815 1.0 0.8413554759111179 18 Q8TBA6,P83436,O14662,O95249,O00461,O60476,Q9H9E3,O43752,Q99747 9
Dag and ip3 signaling 0.6551681125489084 1.6516838691816118 0.0985990127171034 1.0 0.8413554759111179 8 O43865,P13861,P52292 3
Metabolism of folate and pterines 0.626722373952866 1.648283769719071 0.0992944536906632 1.0 0.8413554759111179 9 P34897,Q9H2D1 2
Endosomal vacuolar pathway 0.7779324485342511 1.6425195315307215 0.1004823818127911 1.0 0.8413554759111179 4 Q9UIQ6 1
Recruitment of numa to mitotic centrosomes 0.6089968125794459 1.6368165425512058 0.1016688081602423 1.0 0.8413554759111179 36 Q68CZ6,Q9BUF5,O95684,Q96CS2,P61163,Q13885,O94927,Q9BSJ2,Q14203,Q9H6D7,Q99996,P41208,P07437,O75935,Q7Z4H7,P04350,Q9BVA1,Q15154,P68371,P62258 20
Synthesis of pe 0.8884834091832254 1.6059601661140834 0.1082826624666961 1.0 0.8413554759111179 3 P35790 1
Rho gtpases activate iqgaps 0.5775386567937377 1.6020715749442864 0.1091397828554983 1.0 0.8413554759111179 12 Q9BUF5,Q9BVA1,Q13576,Q13885,P68371,P04350 6
Negative regulation of nmda receptor mediated neuronal transmission 0.6986267163164215 1.5996452706519368 0.1096772994844217 1.0 0.8413554759111179 6 P07196 1
Iron uptake and transport 0.5421059674804692 1.588135722436964 0.112255652072019 1.0 0.8413554759111179 18 Q9Y487,P09601,Q93050,P30519 4
Heme biosynthesis 0.694329766420603 1.580059491653083 0.1140932429561034 1.0 0.8413554759111179 6 P22830 1
Anchoring of the basal body to the plasma membrane 0.5874131350089038 1.5783934156114974 0.1144752569301121 1.0 0.8413554759111179 32 Q68CZ6,O94927,Q99996,P41208,O95684,P07437,Q96CS2,P62258,P61163,Q7Z4H7,Q14203,P30153,Q15154,Q9H6D7,O75935,P68371,P06493,P04350 18
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.6403076923076919 1.577890566823602 0.1145907524909888 1.0 0.8413554759111179 8 P31946,P62258,P27348,P63104,P61981,Q04917,P06493 7
Activation of bad and translocation to mitochondria 0.6637957551522744 1.561703540473278 0.1183578443631736 1.0 0.8413554759111179 7 P31946,P27348,P63104,P31751,Q04917,P62258 6
Phase i functionalization of compounds 0.5545119369964512 1.5505540668295523 0.1210085870859387 1.0 0.8413554759111179 13 O43169,P07099,Q16850,P16435,P30837 5
Aurka activation by tpx2 0.5825062301109261 1.547863804004758 0.1216550908878648 1.0 0.8413554759111179 32 Q68CZ6,O94927,Q99996,P41208,O95684,P07437,Q96CS2,P62258,P61163,Q7Z4H7,Q14203,P30153,Q15154,Q9H6D7,O75935,P68371,P06493,P04350 18
Unwinding of dna 0.6062200414694743 1.5414546444413295 0.1232061734417562 1.0 0.8413554759111179 9 Q9BRT9,Q14566,P33993 3
Signaling by hippo 0.6853324844558277 1.538970016946607 0.1238116161952258 1.0 0.8413554759111179 6 O14641,Q4VCS5 2
Long term potentiation 0.7189325592542406 1.5387186625791367 0.1238729941953011 1.0 0.8413554759111179 5 P07196 1
Unblocking of nmda receptors glutamate binding and activation 0.7189325592542406 1.5387186625791367 0.1238729941953011 1.0 0.8413554759111179 5 P07196 1
Ras activation upon ca2 influx through nmda receptor 0.7189325592542406 1.5387186625791367 0.1238729941953011 1.0 0.8413554759111179 5 P07196 1
Recruitment of mitotic centrosome proteins and complexes 0.5836134699716554 1.5355431170538631 0.1246504744511221 1.0 0.8413554759111179 33 Q68CZ6,O95684,Q96CS2,P61163,P06493,O94927,Q9BSJ2,Q14203,Q9H6D7,Q99996,P41208,P07437,P30153,O75935,Q7Z4H7,P04350,Q15154,P68371,P62258 19
Activation of atr in response to replication stress 0.5336649677732854 1.534952673035213 0.1247954536745266 1.0 0.8413554759111179 18 P15927,P40937,O75419,Q9Y619,Q14566,P33993 6
Ire1alpha activates chaperones 0.5509085650246968 1.533496192035803 0.1251536441836553 1.0 0.8413554759111179 23 P02545,O43731,Q14203,P43307,Q9Y5M8,Q9NWM8 6
Interaction between l1 and ankyrins 0.7499639902172441 1.524611785445535 0.1273559560769039 1.0 0.8413554759111179 4 Q13813 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.6287768509850862 1.5203794747038806 0.1284156300388808 1.0 0.8413554759111179 8 Q9UQ84,Q14191 2
Resolution of d loop structures 0.6287768509850862 1.5203794747038806 0.1284156300388808 1.0 0.8413554759111179 8 Q9UQ84,Q14191 2
Endosomal sorting complex required for transport escrt 0.5757443521790679 1.5153250616520706 0.1296901046380523 1.0 0.8413554759111179 11 Q8WUX9,Q86VN1,Q9H9H4,O43633,Q9NZZ3 5
Homologous dna pairing and strand exchange 0.5189550382897711 1.510808938702799 0.1308371366427656 1.0 0.8413554759111179 15 P40937,Q9UQ84,P15927,Q14191 4
Hdr through single strand annealing ssa 0.5189550382897711 1.510808938702799 0.1308371366427656 1.0 0.8413554759111179 15 P40937,Q9UQ84,P15927,Q14191 4
Rhov gtpase cycle 0.5182154053246614 1.5061136006083151 0.1320380137825765 1.0 0.8451649822304091 15 Q01082,P06753,P67936,Q13813 4
Signaling by wnt in cancer 0.5719415308329692 1.4941828075900123 0.135127844956151 1.0 0.8532800472663836 11 Q16537,Q13362,P30154,P48729,P25054 5
Fcgr3a mediated il10 synthesis 0.6715963446193617 1.4760480698166418 0.1399309882018045 1.0 0.8632796852075314 6 P13861,O43865 2
Late endosomal microautophagy 0.5800586500101912 1.4686755817060495 0.1419208035971326 1.0 0.8646153777064051 10 Q8WUX9,Q9H9H4,Q99816,O43633,P08670 5
Diseases of mitotic cell cycle 0.526048837235725 1.4645584318118925 0.1430414300801086 1.0 0.8651035217041962 14 P11802,Q9H1A4,Q96DE5,P24941,Q00534,Q9UJX5,Q9UJX3 7
Akt phosphorylates targets in the nucleus 0.8513105088315993 1.463243421842031 0.1434007831167156 1.0 0.8651035217041962 3 O43524 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5777376489902739 1.4561241763607164 0.1453582953269552 1.0 0.8651035217041962 10 O60725,Q9HA64,P49366,Q9H2P9 4
Ion transport by p type atpases 0.5890191277854804 1.4512668850908814 0.1467055585927297 1.0 0.8671234931289429 9 Q9HD20 1
Caspase mediated cleavage of cytoskeletal proteins 0.6651802598601227 1.44658657582469 0.1480127482146653 1.0 0.8674671192834186 6 P08670 1
Regulation of localization of foxo transcription factors 0.6635916359163325 1.4392855655984924 0.1500696307913391 1.0 0.8758265427276055 6 P31946,P27348,P63104,P31751,O43524 5
Regulated necrosis 0.5214690172346104 1.4353079697989617 0.1511993576856345 1.0 0.8778965950243736 19 Q8WUX9,P04637,P41440,Q8WUM4,Q16543,O60443,O43633,Q9Y3E7,Q13546 9
Bbsome mediated cargo targeting to cilium 0.6340617180789216 1.4194200846557783 0.1557765803218043 1.0 0.8842557865020775 7 Q9NQ48,P78371,P49368 3
Apc cdc20 mediated degradation of nek2a 0.5545531938390881 1.3971972559316754 0.1623542616850499 1.0 0.8977380255676156 11 Q9H1A4,O60566,Q96DE5,Q9UJX5,Q9UJX3 5
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.5545531938390881 1.3971972559316754 0.1623542616850499 1.0 0.8977380255676156 11 Q9H1A4,O60566,Q96DE5,Q9UJX5,Q9UJX3 5
O linked glycosylation of mucins 0.7172524219478795 1.385895384912411 0.165778850255196 1.0 0.8977380255676156 4 Q10472 1
Copi independent golgi to er retrograde traffic 0.5501941137052214 1.3848309789665805 0.1661041559185581 1.0 0.8977380255676156 30 Q9BUF5,Q9NZ32,Q9BVA1,Q14203,Q13885,Q8TD16,O75935,Q10472,O43237,P68371 10
Association of tric cct with target proteins during biosynthesis 0.5121171223574039 1.3759332488072162 0.168842300278184 1.0 0.9026125711876845 19 O95302,P40763,P49368,Q9Y2T2,P48643,P78371,Q99832,Q15477 8
Pyroptosis 0.599486850950123 1.3734728820876396 0.1696053859467139 1.0 0.9026125711876845 8 O60443 1
Role of phospholipids in phagocytosis 0.7127372523138944 1.3667013565128054 0.1717189325073334 1.0 0.9048831052615198 4 O43865 1
Cyclin d associated events in g1 0.5572137839209813 1.3448119255445248 0.1786859780970884 1.0 0.9209844132422182 10 P11802,P30154,P30153,P24941,Q00534 5
Folding of actin by cct tric 0.5892266085752849 1.321797966466261 0.1862354356846134 1.0 0.933866498793964 8 P78371,Q99832,P49368 3
Phenylalanine and tyrosine metabolism 0.7011155133852351 1.317266696915396 0.1877492441659094 1.0 0.9351587098725848 4 P61457 1
Sema4d in semaphorin signaling 0.583753241830168 1.2942007325429488 0.1955960938273833 1.0 0.9378047373714156 8 Q13464,P35580,Q7Z406,P35579,P60660 5
Activation of the pre replicative complex 0.5057484836436984 1.2912556079192006 0.1966150583748369 1.0 0.9378047373714156 21 P15927,P56282,O75419,P33993,Q14566,Q9Y619 6
Sulfur amino acid metabolism 0.5442938070260186 1.274508516787848 0.2024832562471292 1.0 0.953387264160212 10 Q9UBX3,Q13126 2
Flt3 signaling 0.6576822678084779 1.2681228401554776 0.2047540861786116 1.0 0.960822384128688 5 O43524 1
Interconversion of nucleotide di and triphosphates 0.4888754396197448 1.2501752630914584 0.2112355310598859 1.0 0.9609025552452962 18 P15531,Q13232 2
Budding and maturation of hiv virion 0.5392407117566184 1.2469811770827597 0.2124043994311986 1.0 0.9609025552452962 10 Q8WUX9,Q9H9H4,Q99816,O43633,Q9Y3E7,Q9NZZ3 6
Glutathione synthesis and recycling 0.6843884449907822 1.2460822179271809 0.2127342123661106 1.0 0.9609025552452962 4 P48507,Q8WUX2,Q96KP4 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5359380935685553 1.228983630788592 0.2190779434145078 1.0 0.9784542231599722 10 Q96DE5,Q9UJX3,Q9H1A4,Q9UJX5 4
Biosynthesis of specialized proresolving mediators spms 0.7889400921658947 1.223039443132699 0.2213147989955526 1.0 0.981540458244791 3 Q14914,P34913 2
Synthesis of pc 0.6164265585988937 1.221735332519855 0.2218077302811045 1.0 0.981540458244791 6 P35790 1
Apoptotic factor mediated response 0.5929790950285245 1.2215207457062374 0.2218889156867274 1.0 0.981540458244791 7 O60443 1
Activation of bh3 only proteins 0.5305050275790654 1.1993697305557705 0.2303842120905077 1.0 1.0 10 P31946,P04637,P27348,P63104,P31751,Q04917,P62258 7
Nef mediated downregulation of mhc class i complex cell surface expression 0.6394980840885263 1.1875336575377833 0.2350171886865557 1.0 1.0 5 P04439,Q9BXS5,Q10567 3
Regulation of plk1 activity at g2 m transition 0.5425488464585037 1.185274106851309 0.2359090876972125 1.0 1.0 38 Q68CZ6,O95684,Q96CS2,P61163,P06493,O94927,Q14203,Q9H6D7,Q99996,P41208,P07437,P30153,O75935,Q13616,P04350,Q7Z4H7,Q15154,P68371,P62258 19
Metabolism of nucleotides 0.5629672209966036 1.1750915077642303 0.2399581078194943 1.0 1.0 46 P00813,Q13232,P15531,P36639,P22234,P55263 6
Diseases of dna repair 0.5015878397490771 1.1642253517076884 0.2443326988954848 1.0 1.0 12 Q9UQ84 1
Condensation of prometaphase chromosomes 0.5208860889327079 1.146937684749677 0.2514073763672528 1.0 1.0 10 P67870,O95347,Q15003,P06493,Q9BPX3,P14635,Q9NTJ3 7
Depolymerisation of the nuclear lamina 0.5182228820495149 1.1324243362494328 0.2574560782227324 1.0 1.0 10 P02545,P42166,P42167,P20700,P50402 5
Rnd3 gtpase cycle 0.4658863196785821 1.1255536286635213 0.2603545053608023 1.0 1.0 17 Q86UP2,Q13464,Q9NYL9,Q07065,Q8TAA9 5
Piwi interacting rna pirna biogenesis 0.5273509152869275 1.125474538229628 0.2603880008105772 1.0 1.0 9 Q8N2A8 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.7622522240119096 1.1206109734043277 0.2624534919980241 1.0 1.0 3 P54619 1
Listeria monocytogenes entry into host cells 0.5937691145434916 1.1170789475467886 0.2639605710263653 1.0 1.0 6 P62993,Q99961,P42566,P35222 4
Initiation of nuclear envelope ne reformation 0.4661195733811548 1.1046100390308804 0.269328599188511 1.0 1.0 18 P02545,Q14974,P42166,P30153,P42167,Q14739,P20700,Q86XL3,P50402 9
Hdr through homologous recombination hrr 0.4856610395457787 1.0994029747420353 0.2715923338165393 1.0 1.0 24 P41440,P15927,P56282,P49005,Q9UQ84,Q14191 6
Activation of nmda receptors and postsynaptic events 0.4834112166802379 1.0851331254674743 0.2778626978192711 1.0 1.0 24 Q9BUF5,Q14168,P07196,P52292,Q9BVA1,P10644,P13861,Q13885,P68371,P04350 10
Muscle contraction 0.4820076096994194 1.0762327466136477 0.2818231778626949 1.0 1.0 24 P16615,O43865,P08670,P67936 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6427544192569857 1.069298834715182 0.2849350355349824 1.0 1.0 4 Q00534,P24941 2
Egr2 and sox10 mediated initiation of schwann cell myelination 0.582825389952849 1.0666230172747293 0.2861421024001975 1.0 1.0 6 Q16850 1
Synthesis of pips at the golgi membrane 0.5382520325092776 1.0646288566593365 0.2870439160009623 1.0 1.0 8 Q10713,P42356 2
Collagen biosynthesis and modifying enzymes 0.4944617719255501 1.0599568884028967 0.2891642129342593 1.0 1.0 11 O15460,O75718 2
Protein localization 0.6165062936492851 1.058128013784774 0.2899970843784736 1.0 1.0 80 Q9Y5J9,Q3ZCQ8,P40855,P46379,P51648,Q13505,P09601,P21796,Q9NS69,O60830,Q99595,Q8N4Q1,P06576,O43615,P62072,Q10713,Q5JRX3,Q13011,Q15388,Q9NR77,O75431,Q9Y584,Q15067,Q9Y3D6,P50542,O15254 26
Cilium assembly 0.5793386396055304 1.0380834076884535 0.2992312254472518 1.0 1.0 62 Q68CZ6,Q9BUF5,O95684,Q96CS2,A0AVF1,P61163,Q13885,A6NIH7,P06493,O94927,O00471,Q9Y496,Q14203,Q9H6D7,Q10713,Q99996,P41208,P07437,Q9NQ48,P30153,O75935,Q92538,Q92973,Q9UPT5,Q7Z4H7,P04350,Q9BVA1,P49368,Q7Z4L5,Q15154,P78371,P68371,P62258 33
Rhou gtpase cycle 0.4478388115115673 1.0324969564368944 0.301839372706921 1.0 1.0 16 Q01082,Q9NZM3,Q13813 3
Signaling by flt3 fusion proteins 0.601593221085321 1.0200789065105622 0.3076910397416834 1.0 1.0 5 Q01082,Q14789 2
Pka mediated phosphorylation of creb 0.7333419277243495 1.010438885865439 0.3122850654646356 1.0 1.0 3 P13861 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.7333419277243494 1.010438885865438 0.3122850654646361 1.0 1.0 3 P13861 1
Ros and rns production in phagocytes 0.5051437866750346 1.0082165885996313 0.3133504958933191 1.0 1.0 9 Q9Y487,Q9Y5K8,Q93050,P38606 4
Flt3 signaling in disease 0.5657840437057313 0.988308608861566 0.3230015305225304 1.0 1.0 6 Q01082,Q14789 2
Insulin receptor recycling 0.4914798158066292 0.9870198743135844 0.3236328956625169 1.0 1.0 10 Q9Y487,Q9Y5K8,Q93050,P38606 4
Urea cycle 0.9204545454545484 0.979999435112322 0.327086397494742 1.0 1.0 2 Q9Y619 1
Autophagy 0.5409988849618703 0.9735978913505456 0.330256233739822 1.0 1.0 50 Q9BUF5,Q8WUX9,Q13885,Q96E29,P21796,Q9NS69,P08670,O43633,Q15388,P04350,Q8IWA4,O95140,O94826,P54619,Q9BVA1,P50542,Q9H9H4,Q99816,P68371,O43237 20
Lipophagy 0.6176780409320322 0.9636736631418388 0.3352095624668605 1.0 1.0 4 P54619 1
Cargo trafficking to the periciliary membrane 0.4520799202474378 0.9498417604584924 0.342192663037651 1.0 1.0 21 P49368,O00471,Q9NQ48,A6NIH7,P78371,Q9UPT5,Q10713 7
Ion homeostasis 0.4821793164326083 0.9367153302970156 0.3489050083585572 1.0 1.0 10 O43865 1
Interleukin 2 family signaling 0.7124423963133597 0.9316003261587722 0.3515431145102674 1.0 1.0 3 P40763,P42224 2
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.7124423963133596 0.9316003261587722 0.3515431145102674 1.0 1.0 3 P40763,P42224 2
Transport of inorganic cations anions and amino acids oligopeptides 0.4689167490633616 0.9172180524852124 0.3590283888738232 1.0 1.0 11 Q70HW3,Q9UBX3 2
Costimulation by the cd28 family 0.4370508862759383 0.914163662941892 0.360630854503472 1.0 1.0 14 P31751,Q13362,P30154,Q16537 4
Synthesis of pg 0.7048961163453484 0.9033531747245716 0.3663384832780607 1.0 1.0 3 Q8N2A8 1
Termination of translesion dna synthesis 0.4374534292501086 0.9000982654103215 0.3680679590534204 1.0 1.0 19 P15927,P41440,P56282,P49005 4
Miro gtpase cycle 0.6024413220675449 0.9000658083960368 0.3680852304436266 1.0 1.0 4 Q8IWA4 1
Copi dependent golgi to er retrograde traffic 0.5306715784149931 0.8940556277011233 0.3712921287211146 1.0 1.0 51 Q9BUF5,O43731,Q9P2W9,Q13885,Q9H0B6,Q9Y496,O95239,O15260,Q6NUQ1,Q07866,Q9BW19,Q92538,P24390,O14579,P04350,Q99747,Q9BVA1,P33176,Q9NZ43,Q9Y3B3,P68371,P52732 22
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4752692753566709 0.8940417185020874 0.3712995704079982 1.0 1.0 31 Q9BUF5,Q9NZ32,Q9BVA1,Q14203,Q13885,P31948,O75935,P68371,O43237,P04350 10
Insulin processing 0.4784418917750162 0.8683843749918796 0.38518394569958 1.0 1.0 9 Q9UPT5,O00471 2
Dna damage recognition in gg ner 0.4293010771097559 0.8666141256158288 0.3861534712673691 1.0 1.0 14 P61201,P41208,Q9UBW8,P54727,Q99627,Q9BT78 6
Downregulation of erbb2 signaling 0.5657068974879915 0.8634713213375278 0.3878783807420638 1.0 1.0 5 P31751 1
Sars cov 1 infection 0.4206122074746714 0.8588993192333703 0.3903960650422546 1.0 1.0 16 Q8WUX9,Q8TBF4,Q10472 3
Processing of smdt1 0.4484383966320378 0.8575203118232563 0.3911573942278223 1.0 1.0 12 Q10713,Q8IYU8 2
Signaling by kit in disease 0.5910715427076341 0.8529793243534298 0.3936707700126423 1.0 1.0 4 P40763,P42224 2
Cytochrome p450 arranged by substrate type 0.688800952932601 0.8435778447759787 0.398905348981188 1.0 1.0 3 Q16850 1
Rho gtpases activate rocks 0.4641026380361707 0.8396234902891274 0.4011195242365477 1.0 1.0 10 P35580,P35579,Q7Z406 3
Antigen presentation folding assembly and peptide loading of class i mhc 0.4271574309556311 0.8351731409304844 0.40362023008641 1.0 1.0 19 P04439,Q6P179,Q03519,Q9NZ08 4
E2f mediated regulation of dna replication 0.4534078323535438 0.8313913401387896 0.4057525895907385 1.0 1.0 11 P30154,P30153,Q9Y619 3
Interleukin 35 signalling 0.6854070660522227 0.8310648857997712 0.4059369750856738 1.0 1.0 3 P40763,P42224 2
Interleukin 27 signaling 0.6854070660522227 0.8310648857997712 0.4059369750856738 1.0 1.0 3 P40763,P42224 2
Interleukin 6 family signaling 0.6835637480798724 0.8242832303885697 0.4097786448389975 1.0 1.0 3 P40763,P42224 2
Interleukin 20 family signaling 0.6835637480798724 0.8242832303885697 0.4097786448389975 1.0 1.0 3 P40763,P42224 2
Interleukin 6 signaling 0.6835637480798724 0.8242832303885697 0.4097786448389975 1.0 1.0 3 P40763,P42224 2
Signaling by pdgfr in disease 0.5562866660923501 0.8229034020357218 0.41056292792558 1.0 1.0 5 P40763,P42224,O43815 3
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4375287877697716 0.8167001771901503 0.4140997900469578 1.0 1.0 23 Q13126,Q53EL6,P52597,P20700,P78417,Q9UL46 6
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4593684901106865 0.8143889228640989 0.4154221824090705 1.0 1.0 10 P07196 1
Darpp 32 events 0.4874858273157965 0.8114946383791265 0.4170816706805906 1.0 1.0 8 P10644,P30154,P13861 3
Hedgehog off state 0.5166887193686679 0.8080002216629759 0.4190904545377663 1.0 1.0 51 Q9BUF5,Q9BVA1,Q9Y496,P10644,P28072,P49721,Q7Z4L5,P13861,Q06323,Q13885,O00231,P61289,P28070,P68371,Q99436,P04350,Q9UL46 17
Phosphorylation of the apc c 0.4363802710098774 0.789008606722587 0.4301069761888123 1.0 1.0 12 Q9UJX3,Q9H1A4,Q96DE5,Q9UJX5,P06493 5
Recognition of dna damage by pcna containing replication complex 0.4153204071945921 0.782267843411919 0.4340571808150482 1.0 1.0 18 P15927,P41440,P56282,P49005 4
Cardiac conduction 0.4443492508312374 0.7817048502052425 0.4343880505939324 1.0 1.0 11 O43865 1
Inlb mediated entry of listeria monocytogenes into host cell 0.5733449675642965 0.7803741162457198 0.4351706987174029 1.0 1.0 4 P62993,P42566 2
Mismatch repair 0.4344038829577529 0.7778446346750707 0.4366606109323463 1.0 1.0 12 Q9UQ84,P15927 2
Interleukin 37 signaling 0.6700460829493037 0.7748855860864586 0.438407270078498 1.0 1.0 3 Q06124,P40763 2
Protein folding 0.4762142181641523 0.7723924474975433 0.4398820256671341 1.0 1.0 38 O95302,P40763,Q9BUF5,O15212,Q9BVA1,P49368,Q99471,Q9Y2T2,Q13885,P48643,P78371,Q99832,Q15477,P68371,Q9UHV9,P04350 16
Rho gtpases activate ktn1 0.4596910803244319 0.7715753109314349 0.4403660016666457 1.0 1.0 9 Q86UP2,Q07866,Q9H0B6 3
G1 s specific transcription 0.4497920557115087 0.7636517084542801 0.4450748260808859 1.0 1.0 10 O75419,P31350,Q9Y619 3
Metabolism of nitric oxide nos3 activation and regulation 0.5406376542766236 0.7562000521943155 0.4495292614968957 1.0 1.0 5 P35270 1
Translocation of slc2a4 glut4 to the plasma membrane 0.4671376946118531 0.752065544701969 0.4520116430812857 1.0 1.0 36 Q9BUF5,P54619,Q9UIQ6,Q9BVA1,O00471,Q9Y496,P31751,Q04917,Q13885,P68371,P35579,Q9UPT5,P04350 13
Dna strand elongation 0.4429921057169217 0.7326499404634654 0.4637719633094639 1.0 1.0 29 Q9BRT9,P41440,P15927,P49005,P40937,Q14566,P33993 7
Signaling by hedgehog 0.5199464456812383 0.7260938310695795 0.467781250558372 1.0 1.0 58 Q9BUF5,P49721,P13861,Q13885,P07237,Q9Y496,P10644,P28070,Q99436,P28072,Q6PHR2,O00231,P04350,Q9UL46,Q9BVA1,Q7Z4L5,Q13438,Q06323,P61289,P68371 20
Anti inflammatory response favouring leishmania parasite infection 0.4145421293226128 0.718452549102897 0.4724782955644881 1.0 1.0 13 P35579,P10644,P13861,O43865 4
Ptk6 regulates cell cycle 0.8427518427518429 0.7182482013943366 0.4726042623181543 1.0 1.0 2 P24941 1
Ripk1 mediated regulated necrosis 0.4319758537561073 0.7145238008904038 0.474903344093309 1.0 1.0 11 Q8WUM4,Q16543,P41440,Q13546 4
Negative regulation of met activity 0.5306698743418611 0.7142426787967492 0.4750771303285788 1.0 1.0 5 P62993,P42566 2
Rhobtb1 gtpase cycle 0.4109274853448636 0.7132161436695759 0.4757120181002792 1.0 1.0 20 P61201,Q13464,P78371,Q99832,Q9BT78,P08670 6
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6522273425499177 0.7107841872922467 0.4772179809110308 1.0 1.0 3 P30154,P30153 2
Pp2a mediated dephosphorylation of key metabolic factors 0.6522273425499177 0.7107841872922467 0.4772179809110308 1.0 1.0 3 P30154,P30153 2
Intrinsic pathway for apoptosis 0.4066061272142234 0.7071933306031657 0.4794463426205917 1.0 1.0 19 P31946,P40763,P04637,P27348,P63104,P31751,Q04917,O60443,Q07021,Q9NR28,P62258 11
Regulation of runx3 expression and activity 0.4554819821967943 0.6989885405459695 0.4845591923931134 1.0 1.0 35 P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q9UL46,P25788,Q06323,P61289,O75832,P43686 20
Translesion synthesis by polk 0.4369988696188433 0.6966394278092677 0.486028474691452 1.0 1.0 10 P15927,P41440 2
Pcna dependent long patch base excision repair 0.4042736228647201 0.692844237813692 0.4884073069130052 1.0 1.0 19 P15927,P41440,P56282,P49005 4
Negative regulation of notch4 signaling 0.4656936042384511 0.6914228728239056 0.4892998342327974 1.0 1.0 39 P49721,O00487,P62195,P51665,O43242,P17980,Q9Y6A5,Q9UNM6,P28070,P28074,Q99436,P63104,P28072,P62191,Q15008,O00231,Q13616,Q9UL46,P25788,Q06323,P61289,O75832,P43686 23
Glycerophospholipid biosynthesis 0.445172803322926 0.6903809574251486 0.4899546486895403 1.0 1.0 32 Q9NQZ5,P35790,Q53H12,Q8IV08,Q8N2A8,Q9NPH0,Q9HBU6 7
Rac2 gtpase cycle 0.4446822130025409 0.6874169663721671 0.4918200090441096 1.0 1.0 32 Q7L576,Q8IZP0,P42166,O15173,Q13505,P49257,Q14739,Q5T2T1,Q9NSV4,Q9Y6W5,P50402,Q8TAA9,Q86XL3 13
Rnd2 gtpase cycle 0.3932095400473619 0.6873762534019772 0.4918456578833612 1.0 1.0 16 Q86UP2,P51648,Q03001,Q15058,Q07065,Q8TAA9 6
Pka activation in glucagon signalling 0.8301597051597052 0.6777893784910426 0.4979052465319493 1.0 1.0 2 P13861 1
Interleukin 12 signaling 0.4200832153166883 0.6696301068931035 0.5030936167471607 1.0 1.0 25 Q13126,Q53EL6,P52597,P20700,P78417,P07237,Q9UL46 7
Constitutive signaling by akt1 e17k in cancer 0.4754976154706276 0.6647524421090153 0.5062088454718654 1.0 1.0 7 O43524 1
Translation of replicase and assembly of the replication transcription complex 0.4931108670055252 0.6626816564996815 0.5075344603931509 1.0 1.0 6 O43633,Q8WUX9 2
Processive synthesis on the c strand of the telomere 0.395410621674681 0.6621851100885985 0.5078525956421112 1.0 1.0 14 P15927,Q14191 2
Pyruvate metabolism 0.3917454550169409 0.6574190647958827 0.5109114963252925 1.0 1.0 17 P21796,P11177 2
Scf skp2 mediated degradation of p27 p21 0.461722521445252 0.6508791065351666 0.5151245296712346 1.0 1.0 40 P11802,P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q13616,Q9UL46,P25788,Q06323,P24941,P61289,O75832,P43686 23
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6337941628264152 0.6459057185227803 0.5183404159519267 1.0 1.0 3 P53611,P04637 2
Prolactin receptor signaling 0.6320475313903215 0.6398432500139066 0.5222745115078813 1.0 1.0 3 Q13616 1
Estrogen dependent nuclear events downstream of esr membrane signaling 0.4873014879305007 0.6376429337879188 0.5237061409252983 1.0 1.0 6 O43524 1
N glycan trimming in the er and calnexin calreticulin cycle 0.3910154447492328 0.6362637653725116 0.5246045179364758 1.0 1.0 14 Q04323,P54727,P62191,Q13438,Q9BUN8,Q9UBV2 6
Activation of smo 0.8169533169533205 0.6361172565051019 0.524699998759256 1.0 1.0 2 Q9Y496 1
Smooth muscle contraction 0.4251388832583849 0.635475011057392 0.5251186594661701 1.0 1.0 10 P67936 1
Platelet homeostasis 0.3999044973019041 0.6346720205831465 0.5256423454814507 1.0 1.0 13 Q16537,Q16539,Q13362,P30154,P16615 5
Rhobtb2 gtpase cycle 0.3979594219152247 0.6340314534120499 0.5260602953788949 1.0 1.0 20 Q16543,Q9NYL9,P78371,Q99832,P12814,Q96DH6 6
Negative regulation of the pi3k akt network 0.3885599647936664 0.6218585331952912 0.5340348937047652 1.0 1.0 14 Q16537,P31751,Q13362,P30154,O43815 5
Defective intrinsic pathway for apoptosis 0.3823781233453247 0.6210813311821529 0.5345461119029307 1.0 1.0 16 P02545,P04632,O43524,Q08379,P20700,P62258 6
Cd163 mediating an anti inflammatory response 0.8105036855036921 0.6160708828518692 0.537847738316533 1.0 1.0 2 P35579 1
Assembly of the hiv virion 0.808353808353807 0.6094355052643635 0.5422358098214244 1.0 1.0 2 Q9H9H4 1
Gap filling dna repair synthesis and ligation in gg ner 0.3904793762135933 0.6089310251818665 0.5425701586599607 1.0 1.0 19 P15927,P41440,P56282,P49005 4
Irs mediated signalling 0.5040189428126143 0.6046073178483714 0.5454399432026791 1.0 1.0 5 P62993,P31751 2
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3992959265186186 0.6026066525745202 0.5467703937033881 1.0 1.0 22 P15927,P41440,P56282,P49005 4
Rhobtb gtpase cycle 0.4238002435973038 0.5986509657171624 0.5494056620118182 1.0 1.0 30 P61201,Q13464,Q16543,Q9NYL9,P78371,Q99832,P12814,Q9BT78,Q96DH6,P08670 10
Basigin interactions 0.4603017415503926 0.5966383712972778 0.5507488469453747 1.0 1.0 7 P53985 1
Interleukin 23 signaling 0.8034398034398081 0.5943593622719526 0.5522717825148091 1.0 1.0 2 P07237 1
Copi mediated anterograde transport 0.4928838839342983 0.5922582079532557 0.5536776966766386 1.0 1.0 56 Q9BUF5,P61163,O43731,Q08379,P83436,O60763,O95249,Q13885,Q9H9E3,Q01082,Q9NZ32,Q14203,O75935,Q92538,P24390,O14579,P04350,Q99747,Q9BVA1,Q13813,Q9Y3B3,Q14789,P68371,O43237 24
Recycling pathway of l1 0.39960824429576 0.5851818888844214 0.5584254214268589 1.0 1.0 23 Q9BUF5,Q9BVA1,P50570,Q13885,P68371,O95239,P04350 7
Dna replication initiation 0.4568607292806729 0.5814440128123937 0.5609412414891299 1.0 1.0 7 P56282 1
Glycogen storage diseases 0.5227113419186096 0.5807287409084952 0.5614232880458667 1.0 1.0 4 O43826 1
Transcriptional regulation by runx3 0.4489658669656308 0.5755643331987707 0.5649096947932044 1.0 1.0 40 P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P04637,P35222,P28072,P62191,Q15008,O00231,Q9UL46,P25788,O43524,Q06323,P61289,O75832,P43686 23
G protein mediated events 0.4038741606437894 0.5659650141655279 0.57141756382032 1.0 1.0 11 O43865,P13861,P52292 3
Er quality control compartment erqc 0.6094316329506517 0.5628533131480985 0.5735347735320002 1.0 1.0 3 Q13438 1
Regulation of ifng signaling 0.6093405729927952 0.5625493853793819 0.5737417659802597 1.0 1.0 3 P42224 1
Regulation of ifna signaling 0.6093405729927952 0.5625493853793819 0.5737417659802597 1.0 1.0 3 P42224 1
Interleukin 12 family signaling 0.4101580145132144 0.5544355745649737 0.5792807853906266 1.0 1.0 28 Q13126,Q53EL6,P52597,P20700,P14174,P78417,P07237,Q9UL46 8
Synthesis of pips at the plasma membrane 0.4332871976687815 0.5533651631272745 0.5800133885623326 1.0 1.0 8 Q96T51 1
Cyclin a cdk2 associated events at s phase entry 0.4496356021017349 0.5474729960532302 0.5840538177129622 1.0 1.0 42 P11802,P31751,P28072,P49721,Q06323,P24941,O00231,P61289,P28070,Q9UL46 10
Sensory processing of sound by outer hair cells of the cochlea 0.3921728231166823 0.5457851108844456 0.5852136591098611 1.0 1.0 12 Q01082,Q12792,Q13813,P35579,P15311 5
Met activates ras signaling 0.6039938556067523 0.5447957008157501 0.5858940358542721 1.0 1.0 3 P62993,Q96S59 2
Rhod gtpase cycle 0.4016889271598141 0.5413046425022263 0.5882976211041333 1.0 1.0 26 Q9UEY8,P42166,O15173,P49257,Q14739,Q9NSV4,P20700,P12814,Q8TAA9,P50402 10
Ncam signaling for neurite out growth 0.4465381458047116 0.536436317031969 0.5916570375485353 1.0 1.0 7 Q13813 1
Signaling by insulin receptor 0.3696471600445662 0.524785001081615 0.59973265942341 1.0 1.0 17 Q9Y487,P31751,Q93050 3
Factors involved in megakaryocyte development and platelet production 0.4495401973190352 0.5158822786375739 0.6059366319267121 1.0 1.0 44 O95140,Q9BUF5,P52732,Q07866,Q9H0B6,Q9BVA1,P33176,Q9Y496,P10644,P13861,P24941,Q13885,Q9BW19,P68371,O95239,P04350,Q8IWA4 17
Signaling by ptk6 0.3935717835857064 0.5133368161963554 0.6077157349094662 1.0 1.0 11 Q07666,P11802,P24941 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4542236582788113 0.4995931452607158 0.6173615854783323 1.0 1.0 6 P62993,P31751 2
E3 ubiquitin ligases ubiquitinate target proteins 0.3652758436778606 0.4992413498426331 0.6176093675602454 1.0 1.0 17 P04439,P50542,O75150 3
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3783266101447574 0.4983723733012032 0.6182216052635181 1.0 1.0 21 P15927,P41440,P56282,P49005 4
Rho gtpases activate paks 0.3902931486646112 0.4968399132097026 0.6193019465355944 1.0 1.0 11 P35579,P35580 2
Dopamine neurotransmitter release cycle 0.7693488943489011 0.4935517425365954 0.6216227889677579 1.0 1.0 2 Q13136 1
Signaling by notch4 0.4352823262384144 0.481042368364056 0.6304863868382327 1.0 1.0 41 P49721,O00487,P62195,P51665,O43242,P17980,Q9Y6A5,Q9UNM6,P28070,P28074,Q99436,P63104,P28072,P62191,Q15008,O00231,Q13616,Q9UL46,P25788,Q06323,P61289,O75832,P43686 23
Translesion synthesis by polh 0.3704549831425885 0.4724224555386682 0.6366252792092766 1.0 1.0 13 P15927,P41440 2
Acyl chain remodelling of pc 0.5815410506885876 0.4723609989402607 0.6366691374610951 1.0 1.0 3 Q9NP80 1
Telomere c strand lagging strand synthesis 0.3833634320746049 0.4720351929396902 0.6369016688534908 1.0 1.0 24 P15927,P41440,P49005,Q14191 4
Post translational modification synthesis of gpi anchored proteins 0.414655821984363 0.4699754890552218 0.6383725295264198 1.0 1.0 8 Q9ULX3,Q92643,Q969N2 3
Fgfr1 mutant receptor activation 0.3845579351427526 0.4683007390428543 0.6395695400030867 1.0 1.0 11 P40763,P42224,O95684,Q16630,O95429,Q92614,O94905 7
Signaling by alk in cancer 0.4156730614212796 0.465982824515593 0.6412277946321487 1.0 1.0 35 Q86WB0,P40763,P67936,Q07866,O94979,P33176,P06753,P10644,Q14203,P12270,P35579,P49589,Q8IWJ2,O43815 14
Type i hemidesmosome assembly 0.7592137592137587 0.4649880138635152 0.6419400401617739 1.0 1.0 2 Q03001 1
Apoptotic cleavage of cell adhesion proteins 0.4673901204365429 0.461970346026783 0.6441025860246687 1.0 1.0 5 Q16625,P35222 2
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4104615384615453 0.4517157382755628 0.6514737788286686 1.0 1.0 8 Q07812,P04637,O14965,Q86X55,P14635,Q99873,P06493 7
Collagen formation 0.3567149359043723 0.441275877397653 0.6590132874831687 1.0 1.0 14 P13674,O15460,Q15149,Q03001,O75718,P07237 6
Mitochondrial biogenesis 0.4132909521450024 0.4365933466107402 0.6624062886957454 1.0 1.0 36 O75964,Q13505,P00846,P06576 4
Cytosolic iron sulfur cluster assembly 0.4583461420227634 0.4285766199694155 0.668231363118724 1.0 1.0 5 O75027,Q96T76,Q9Y5Y2,P28340 4
Glutathione conjugation 0.3620546886199767 0.428169053714566 0.6685280450142828 1.0 1.0 13 P28161,Q96KP4,P48507,Q99735,Q8WUX2,P78417 6
Vesicle mediated transport 0.3779760514702915 0.4275112918316104 0.6690069623528763 1.0 1.0 264 Q08379,Q04917,P83436,Q9UQ16,Q86VN1,O00461,Q8TD16,O43633,O15260,Q5JRA6,O75935,Q14671,P24390,O14579,Q96D71,P54619,O94979,Q9BVA1,Q9H9H4,Q99816,P52732,P62258,Q9UHD9,Q9BUF5,Q8WUX9,Q9UBW8,Q9UBC2,P61163,O43731,O95249,O60763,O60664,Q9H9E3,Q9NVZ3,Q9Y5X1,Q9H3P7,P49257,Q8WTV0,O43752,Q6NUQ1,Q96PC5,P82094,Q9BW19,Q99747,Q13813,Q14789,P68371,P35579,Q9P2W9,Q9Y3P9,Q01082,Q9H0B6,P31751,Q14203,Q8IWJ2,Q8TBA6,Q9NZM3,Q10472,Q9UPT5,P61201,Q9UIQ6,Q9Y3B3,O43237,Q9Y6Y8,P50570,Q13885,O15027,Q9NZ32,O00471,Q9Y496,Q99627,Q9Y5X3,Q9BT78,O95239,Q9NZZ3,Q07866,Q15907,P55327,P04350,P33176,Q10567,Q9NZ43,O60476,O14641,Q8TC07 85
Peroxisomal lipid metabolism 0.361803440615663 0.4268619589826119 0.6694798746136859 1.0 1.0 13 O15254,P51648 2
Nuclear envelope ne reassembly 0.4506238464094487 0.4205318920040892 0.6740969365228424 1.0 1.0 51 Q9BUF5,Q8WUX9,P42167,Q96EE3,Q13885,Q8NFH5,P06493,P57740,Q86XL3,O43633,P37198,P53990,Q14974,P42166,P30153,Q14739,P20700,Q92973,Q9BTX1,P04350,P02545,Q9BVA1,Q8N1F7,P68371,P50402 25
Polymerase switching 0.3508854060776728 0.4097651467427635 0.6819782355739574 1.0 1.0 14 P41440,P49005 2
Signaling by fgfr1 in disease 0.3639308266176317 0.4010019781536107 0.6884186675040516 1.0 1.0 12 P40763,P42224,O95684,Q16630,O95429,Q92614,O94905 7
Peroxisomal protein import 0.3640338312380669 0.3995854425987942 0.68946188031266 1.0 1.0 22 P50542,O15254,Q13011 3
Interleukin 9 signaling 0.7340294840294868 0.3971722539241762 0.69124044123074 1.0 1.0 2 P40763 1
Interleukin 21 signaling 0.7340294840294868 0.3971722539241762 0.69124044123074 1.0 1.0 2 P40763 1
Proton coupled monocarboxylate transport 0.732800982800994 0.393986516493898 0.6935909940909455 1.0 1.0 2 P53985 1
Degradation of cysteine and homocysteine 0.44639789532331 0.3857720794773844 0.6996654750556544 1.0 1.0 5 Q9UBX3 1
Dna damage bypass 0.3670677107249985 0.381460133308928 0.702861847889575 1.0 1.0 24 P15927,P41440,P56282,P49005 4
Cdt1 association with the cdc6 orc origin complex 0.408760604330044 0.380817225939076 0.7033388762479371 1.0 1.0 38 P28072,P49721,Q06323,O00231,P61289,P28070,Q9Y619,Q9UL46 8
Wnt mediated activation of dvl 0.5497777645991764 0.3766286832174843 0.7064495687078898 1.0 1.0 3 O14641 1
Regulation of runx1 expression and activity 0.4636922942252785 0.3710437560427089 0.7106049415714115 1.0 1.0 4 Q00534 1
Transferrin endocytosis and recycling 0.3630838924042934 0.3655385688442281 0.7147094219012209 1.0 1.0 11 Q9Y487,Q93050 2
Dual incision in gg ner 0.353583262793287 0.360287497724468 0.7186321477961981 1.0 1.0 21 P15927,P41440,P56282,P49005 4
Polymerase switching on the c strand of the telomere 0.3369328095891909 0.3588060364548905 0.7197401965332304 1.0 1.0 16 P41440,P49005 2
Plasma lipoprotein remodeling 0.7186732186732283 0.3582194610948231 0.7201790844608609 1.0 1.0 2 P07237 1
Rho gtpases activate cit 0.3593538608301287 0.3484321882848694 0.7275156324730463 1.0 1.0 11 P35579,P35580 2
Interleukin 15 signaling 0.7122235872235909 0.3424386814368314 0.73202078253509 1.0 1.0 2 P40763 1
Regulation of tp53 activity through phosphorylation 0.3796292400218581 0.3340633905135721 0.7383317247832126 1.0 1.0 31 P54619,Q13472,Q16539,P15927,P24941,P40937,Q9UQ84,Q14191 8
Golgi to er retrograde transport 0.488611157660877 0.3303290872336122 0.7411513168657191 1.0 1.0 76 Q9BUF5,O43731,Q9P2W9,Q13885,Q9NZ32,Q9H0B6,Q9Y496,Q14203,Q8TD16,O95239,O15260,Q6NUQ1,Q07866,Q9BW19,O75935,P24390,Q10472,O14579,Q99747,P04350,Q9BVA1,P33176,Q9NZ43,Q9Y3B3,P68371,O43237,P52732 27
Aquaporin mediated transport 0.4292527201347134 0.3272401590504909 0.7434862489225871 1.0 1.0 5 Q99797,P13861 2
Regulation of tp53 activity through association with co factors 0.704545454545467 0.3241161311890621 0.7458501146692595 1.0 1.0 2 P31751 1
Raf activation 0.3539221106293888 0.3239605867142842 0.7459678736405828 1.0 1.0 11 Q13362,P30154,Q16537 3
Signaling by braf and raf1 fusions 0.3528300942562847 0.3225724706282194 0.7470190453389933 1.0 1.0 23 Q53H12,P02545,Q9NRY5 3
Rhoa gtpase cycle 0.4112944621239239 0.3214838793657308 0.7478437268379696 1.0 1.0 43 Q86UP2,Q96HY6,O75116,P41440,P42166,O15173,Q92974,Q13464,Q8NBN3,P42167,P49257,P30519,Q14739,Q8WVM8,Q9NSV4,Q8TAA9,Q9H2G2 17
Interferon gamma signaling 0.3391975052766202 0.3137392606035689 0.7537190795514146 1.0 1.0 13 P19474 1
Constitutive signaling by overexpressed erbb2 0.5249347446896386 0.3082318522216098 0.7579059169942801 1.0 1.0 3 Q16543 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.4227116259467725 0.299195541412614 0.7647908510133499 1.0 1.0 49 Q9BUF5,Q9BVA1,P28072,P49721,Q06323,Q13885,O00231,P61289,P28070,P68371,Q9UL46 11
Ptk6 regulates proteins involved in rna processing 0.6879606879606941 0.2863229304774035 0.7746307969870916 1.0 1.0 2 Q07666 1
Orc1 removal from chromatin 0.4161521626225777 0.2790126980916174 0.7802350799228734 1.0 1.0 48 P49721,O00487,P62195,P33993,O43242,P49736,P25205,P17980,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,P33991,Q15008,O00231,Q13616,Q9Y619,Q9UL46,P25788,Q06323,P24941,P61289,O75832,Q14566,P43686 27
Signaling by leptin 0.683353808353814 0.2762706729371392 0.7823401792668858 1.0 1.0 2 P40763 1
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.6833538083538092 0.2762706729371296 0.7823401792668931 1.0 1.0 2 Q6SZW1 1
Pi 3k cascade fgfr1 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Stat5 activation 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr4 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Frs mediated fgfr4 signaling 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Tie2 signaling 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr2 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Frs mediated fgfr2 signaling 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Frs mediated fgfr3 signaling 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr3 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Met activates ptpn11 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Frs mediated fgfr1 signaling 0.6833538083538091 0.2762706729371287 0.7823401792668938 1.0 1.0 2 P62993 1
Hedgehog ligand biogenesis 0.3941124985499259 0.2758888880065847 0.782633408908024 1.0 1.0 40 P28072,P49721,Q13438,Q06323,O00231,P61289,P28070,P07237,Q9UL46 9
Notch3 activation and transmission of signal to the nucleus 0.5119673811826615 0.2750774491034634 0.78325673651173 1.0 1.0 3 P67809 1
Switching of origins to a post replicative state 0.4374159587982066 0.2739815660998955 0.7840987879382928 1.0 1.0 57 P49721,O00487,P62195,P33993,O43242,P49736,P25205,P17980,Q96DE5,Q9UNM6,P28070,P28074,Q99436,Q9UJX5,Q9UJX3,P28072,P62191,Q15008,P33991,O00231,Q13616,Q9Y619,Q9UL46,P25788,Q9H1A4,Q06323,P24941,P61289,O75832,Q9UJX4,Q14566,P43686 32
Peptide hormone metabolism 0.3231321921094335 0.2685706680716576 0.7882600866862695 1.0 1.0 14 Q9UPT5,P67812,O00471 3
Egfr downregulation 0.3640305058797891 0.265640903390129 0.7905157806525098 1.0 1.0 8 Q9Y6I3,P62993,Q9UBC2,P42566 4
Rna polymerase iii transcription 0.3454433497536824 0.265196270400664 0.7908582678665264 1.0 1.0 10 P62875,Q12789,Q9Y5Q9,Q9UKN8,Q9Y5Q8,O15160,P19388,Q8WUA4,P05455 9
Cross presentation of soluble exogenous antigens endosomes 0.3834909218953726 0.2649664079730813 0.7910353397154157 1.0 1.0 37 P28072,P49721,Q06323,O00231,P61289,Q9UBG0,P28070,Q9UL46 8
Ca dependent events 0.3768028226110255 0.2631912773646104 0.7924031535308387 1.0 1.0 7 P13861,P52292 2
Hedgehog on state 0.3968023690200506 0.2619809357713802 0.7933361400632681 1.0 1.0 42 Q9Y496,P28072,P49721,Q06323,Q6PHR2,O00231,P61289,P28070,Q99436,Q9UL46 10
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5054158574875666 0.2590350458798433 0.7956082003733085 1.0 1.0 3 P24941 1
Slc mediated transmembrane transport 0.3366015460248188 0.2564518258333277 0.7976019742219762 1.0 1.0 22 P53985,Q70HW3,Q9UBX3 3
Rna polymerase iii transcription initiation from type 1 promoter 0.3453370267774757 0.2469917230082194 0.804914629751653 1.0 1.0 9 P62875,Q12789,Q9Y5Q9,Q9UKN8,Q9Y5Q8,O15160,Q8WUA4,P19388 8
Rap1 signalling 0.6661547911547929 0.2405144102266489 0.8099314933361716 1.0 1.0 2 P63104 1
Lagging strand synthesis 0.3256472479701436 0.2342766523688439 0.8147702103146766 1.0 1.0 20 P15927,P41440,P49005 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3254000094337769 0.2330893506222735 0.8156920241516068 1.0 1.0 20 Q02818,Q86UP2,Q07065,O43852 4
Regulation of hmox1 expression and activity 0.3954347971119366 0.2290932710372165 0.818796423336166 1.0 1.0 44 P28072,P49721,Q06323,P09601,P61289,P28070,Q9UL46 7
Ion channel transport 0.348923089055357 0.2258763281316874 0.8212976094673077 1.0 1.0 28 Q9Y487,Q9HD20,Q93050,P16615 4
Retrograde transport at the trans golgi network 0.3262429674909153 0.2218372799268773 0.824440557233753 1.0 1.0 21 P83436,P82094,O60664,O14662,Q9H9E3,O43752,Q8IWJ2,Q99747 8
Uptake and function of diphtheria toxin 0.409342347879536 0.2120876989015191 0.8320386162693514 1.0 1.0 4 P08238,P13639,Q16881 3
Inla mediated entry of listeria monocytogenes into host cells 0.6492628992629019 0.2081925204545281 0.835078648455432 1.0 1.0 2 P35222 1
Synthesis of ip2 ip and ins in the cytosol 0.6477272727272788 0.2053942952374693 0.8372640770085202 1.0 1.0 2 Q9NPH2 1
Asymmetric localization of pcp proteins 0.3731218787495375 0.2018484379097418 0.8400352128490092 1.0 1.0 38 P28072,P49721,Q06323,O00231,P61289,O14641,P28070,Q9UL46 8
Membrane trafficking 0.3823792937735621 0.1982308234461744 0.8428644723517367 1.0 1.0 257 Q08379,Q04917,P83436,Q9UQ16,Q86VN1,O00461,Q8TD16,O43633,O15260,Q5JRA6,O75935,Q14671,P24390,O14579,Q96D71,P54619,O94979,Q9BVA1,Q9H9H4,Q99816,P52732,P62258,Q9UHD9,Q9BUF5,Q8WUX9,Q9UBW8,Q9UBC2,P61163,O43731,O95249,O60763,O60664,Q9H9E3,Q9NVZ3,Q9Y5X1,Q9H3P7,P49257,O43752,Q6NUQ1,Q96PC5,P82094,Q9BW19,Q99747,Q13813,Q14789,P68371,P35579,Q9P2W9,Q9Y3P9,Q01082,Q9H0B6,P31751,Q14203,Q8IWJ2,Q8TBA6,Q9NZM3,Q10472,Q9UPT5,P61201,Q9UIQ6,Q9Y3B3,O43237,Q9Y6Y8,P50570,Q13885,O15027,Q9NZ32,O00471,Q9Y496,Q99627,Q9Y5X3,Q9BT78,O95239,Q9NZZ3,Q07866,Q15907,P55327,P04350,P33176,Q10567,Q9NZ43,O60476,O14641,Q8TC07 84
Regulation of pten stability and activity 0.3777782432135125 0.1974861087678747 0.843447150983105 1.0 1.0 40 P31751,P28072,P49721,Q06323,O00231,P61289,P28070,Q9UL46 8
Rac3 gtpase cycle 0.3512120370906814 0.1944809419553176 0.8457993169519264 1.0 1.0 31 Q7L576,Q8IZP0,P42166,O15173,P49257,Q14739,Q5T2T1,Q9UQB8,Q9NSV4,Q9Y6W5,Q8TAA9,P50402 12
Synthesis secretion and deacylation of ghrelin 0.4755392041754874 0.1922580512641023 0.8475400756126119 1.0 1.0 3 P67812 1
Organelle biogenesis and maintenance 0.497559769512936 0.1904177803167296 0.8489817658874481 1.0 1.0 98 Q68CZ6,Q9BUF5,O95684,Q96CS2,Q13505,Q13885,A6NIH7,P00846,Q16891,O94927,P06576,O00471,Q9Y496,Q14203,Q9H6D7,Q10713,P41208,P07437,P17152,Q9NQ48,O75935,O75964,O75431,Q92973,Q9UPT5,Q7Z4H7,P04350,P54619,Q9BVA1,P49368,Q16539,Q7Z4L5,Q15154,P78371,P68371,P62258 36
Cellular response to hypoxia 0.373216592472512 0.1893701088218477 0.8498027502848085 1.0 1.0 39 P28072,P49721,Q06323,P61289,P28070,Q9Y241,Q9UL46 7
Rhog gtpase cycle 0.3571640342242633 0.1813956294486483 0.8560570491693675 1.0 1.0 34 Q86UP2,Q7L576,P34897,P42166,O15173,Q13576,P49257,Q5T2T1,Q9NSV4,P50402,Q8TAA9,Q86XL3 12
Unfolded protein response upr 0.3714296056453726 0.1812651659220328 0.8561594466376268 1.0 1.0 39 P02545,O43731,Q14203,P43307,Q9Y5M8,Q9NWM8 6
Degradation of axin 0.362398250304108 0.1789236674197318 0.8579976387424486 1.0 1.0 36 P28072,P49721,Q06323,O00231,P61289,P28070,Q9UL46 7
Acyl chain remodelling of pe 0.6320638820638858 0.1782030784424523 0.8585634921735084 1.0 1.0 2 Q9NP80 1
Signaling by erbb2 0.3208128078817605 0.1728098176147746 0.8628009198089128 1.0 1.0 10 O60610,P07900,P62993,P31751,Q9UNE7,Q93034,Q16543,P19174,P61586 9
Mrna decay by 5 to 3 exoribonuclease 0.3237692870890833 0.1708496183712503 0.864342012784235 1.0 1.0 9 Q86TB9 1
Wax and plasmalogen biosynthesis 0.3915181315304272 0.1690582018912912 0.8657508616845602 1.0 1.0 4 Q6IAN0,O00116,O15228 3
Calnexin calreticulin cycle 0.3347692307692323 0.1673553143177857 0.867090483244314 1.0 1.0 8 P27824,P14314,P30101,Q14697,Q9NYU2,Q13438,Q9UBV2 7
Receptor mediated mitophagy 0.4626728110598999 0.1668650027194076 0.8674762707980899 1.0 1.0 3 P67870,Q96HS1 2
Bmal1 clock npas2 activates circadian gene expression 0.6240786240786282 0.165292465088747 0.8687137892351784 1.0 1.0 2 P43490 1
Diseases of mismatch repair mmr 0.461443932411665 0.164548585215867 0.8692993024750604 1.0 1.0 3 P20585,P43246 2
Metabolism of polyamines 0.3615416841461276 0.16241139315686 0.8709818995104013 1.0 1.0 37 P28072,P49721,Q06323,O00231,P61289,P28070,Q9UL46 7
Integrin signaling 0.3722717491546309 0.1623202807385991 0.8710536447441684 1.0 1.0 5 P62993,P18031,Q9Y490,P46108 4
Platelet aggregation plug formation 0.3722717491546309 0.1623202807385991 0.8710536447441684 1.0 1.0 5 P62993,P18031,Q9Y490,P46108 4
Degradation of dvl 0.364285583675295 0.1619883846282174 0.8713150007875212 1.0 1.0 38 P28072,P49721,Q06323,O00231,P61289,O14641,P28070,Q9UL46 8
Neurotransmitter release cycle 0.3550991012304988 0.1601783165431897 0.8727406097322461 1.0 1.0 6 O14936,Q13136,O75915 3
Postmitotic nuclear pore complex npc reformation 0.3218098085321774 0.1586806767736164 0.8739204629700494 1.0 1.0 24 P57740,Q96EE3,Q8N1F7,Q8NFH5,Q92973,P37198,Q9BTX1 7
G1 s dna damage checkpoints 0.3650306416799679 0.1529257592442715 0.8784568218948219 1.0 1.0 39 P28072,P49721,Q06323,P24941,O00231,P61289,P28070,Q9UL46 8
Defective cftr causes cystic fibrosis 0.3726500589796194 0.1498439117300678 0.8808877638932344 1.0 1.0 42 P49721,O00487,P62195,P51665,O43242,P17980,Q9BUN8,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q9UBV2,O94905,Q9UL46,P25788,Q13438,Q06323,P61289,O75832,P43686 24
Abc transporter disorders 0.3726500589796194 0.1498439117300678 0.8808877638932344 1.0 1.0 42 P49721,O00487,P62195,P51665,O43242,P17980,Q9BUN8,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q9UBV2,O94905,Q9UL46,P25788,Q13438,Q06323,P61289,O75832,P43686 24
Biological oxidations 0.3697748219946147 0.1493219584497282 0.8812995891773121 1.0 1.0 41 O43169,Q99735,P07099,Q9NUJ1,Q16850,P16435,P21964,P30837,P48507,P78417 10
Mapk3 erk1 activation 0.3810694529809498 0.1461361987873303 0.8838138706512442 1.0 1.0 4 Q06124,Q02750,P06493 3
Stabilization of p53 0.3571222049399421 0.1432570240399867 0.8860871955240308 1.0 1.0 37 P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P04637,P28072,P62191,Q15008,O00231,Q9UL46,P25788,Q06323,P61289,O75832,P43686 21
Signaling by cytosolic fgfr1 fusion mutants 0.314085346135975 0.1400594473529508 0.8886130210231269 1.0 1.0 9 P40763,P42224,O95684,Q16630,Q92614 5
Er to golgi anterograde transport 0.4577598892813228 0.1386142094737753 0.8897550141770718 1.0 1.0 80 Q9BUF5,P61163,O43731,Q08379,P83436,O95249,O60763,Q13885,Q9H9E3,O15027,Q01082,Q9NZ32,Q5H9R7,Q14203,P49257,Q5JRA6,Q96PC5,O75935,Q92538,P24390,O14579,P35606,Q99747,P04350,O94979,Q9BVA1,Q13813,Q9Y3B3,Q14789,P68371,O43237,Q9Y6Y8 32
Methylation 0.3309831697094136 0.1252445735115273 0.9003299304751808 1.0 1.0 7 P78417 1
Inositol phosphate metabolism 0.3556716876729343 0.124152168213782 0.9011947933739044 1.0 1.0 5 Q9NPH2,Q01968,Q9BW91,Q9UNW1 4
Rhof gtpase cycle 0.2894413724083626 0.1168130681086907 0.9070081877989526 1.0 1.0 17 Q9UEY8,P42166,P42167,Q13459,Q9Y6M7,Q9NSV4,P20700,P12814,Q8TAA9 9
Neurotransmitter receptors and postsynaptic signal transmission 0.3506606487992463 0.1162332419657312 0.9074676920144245 1.0 1.0 37 Q9BUF5,Q14168,P07196,P52292,Q9BVA1,P10644,P13861,Q13885,P68371,P04350 10
Oncogene induced senescence 0.3265099201473493 0.1139876736510631 0.9092475647542836 1.0 1.0 7 P11802,Q00534 2
Constitutive signaling by egfrviii 0.3643213951742936 0.1130395424912256 0.909999205732766 1.0 1.0 4 Q16543 1
Signaling by erbb2 ecd mutants 0.3643213951742936 0.1130395424912256 0.909999205732766 1.0 1.0 4 Q16543 1
Signaling by egfr in cancer 0.3643213951742936 0.1130395424912256 0.909999205732766 1.0 1.0 4 Q16543 1
Constitutive signaling by ligand responsive egfr cancer variants 0.3643213951742936 0.1130395424912256 0.909999205732766 1.0 1.0 4 Q16543 1
Signaling by erbb2 in cancer 0.3643213951742936 0.1130395424912256 0.909999205732766 1.0 1.0 4 Q16543 1
Global genome nucleotide excision repair gg ner 0.3497186760834417 0.1123936144761765 0.9105113181584864 1.0 1.0 37 P61201,P41208,P41440,P15927,Q99627,P56282,P49005,P40937 8
Myogenesis 0.3232394760532687 0.1060209574061756 0.9155657242933531 1.0 1.0 7 O60271,Q16539,P35221 3
Regulation of runx2 expression and activity 0.359355374214214 0.1057046888135084 0.915816660061838 1.0 1.0 41 P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q13616,Q9UL46,P42224,P25788,Q06323,P61289,O75832,P43686 22
Rna polymerase iii transcription termination 0.3449123885644171 0.1019881165307227 0.9187661075318244 1.0 1.0 5 P62875,O15160,P05455,P19388 4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2874282319618328 0.0983465637509451 0.9216571048369766 1.0 1.0 13 P78371,Q99832 2
Degradation of gli1 by the proteasome 0.3513160683265293 0.0959855845182357 0.9235320215831576 1.0 1.0 39 P49721,O00487,P62195,P51665,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P28072,P62191,Q15008,O00231,Q13616,Q9UL46,P25788,Q06323,P61289,O75832,P43686 21
Abc family proteins mediated transport 0.383913550755479 0.0866845556368758 0.9309222530183288 1.0 1.0 52 O15439,P40855,P28072,P49721,Q13438,Q06323,P61289,P28070,P08183,Q9UL46 10
G2 m dna replication checkpoint 0.4110599078340912 0.0860547837507678 0.9314228675661302 1.0 1.0 3 P14635,P06493 2
Role of abl in robo slit signaling 0.345605383768493 0.0814003826461692 0.9351235448146018 1.0 1.0 4 Q7Z460 1
Rna polymerase iii chain elongation 0.3448063921327632 0.0801743712252903 0.936098573329884 1.0 1.0 4 P62875,O15160,P19388 3
Rna polymerase iii transcription initiation from type 3 promoter 0.3448063921327632 0.0801743712252903 0.936098573329884 1.0 1.0 4 P62875,O15160,P19388 3
Vxpx cargo targeting to cilium 0.2888608657252574 0.0746844789012628 0.9404657572232328 1.0 1.0 10 Q9UPT5,O00471 2
Transcriptional regulation by e2f6 0.3178829011804744 0.0745860132898831 0.9405441029009662 1.0 1.0 6 Q15910 1
Transport to the golgi and subsequent modification 0.4488198281461029 0.0668274001853612 0.9467191099688907 1.0 1.0 84 Q9BUF5,P61163,O43731,Q08379,P83436,O95249,O60763,Q13885,Q9H9E3,O15027,Q01082,Q9NZ32,Q5H9R7,Q14203,P49257,Q5JRA6,Q96PC5,O75935,Q92538,P24390,O14579,P35606,Q99747,P04350,O94979,Q9BVA1,Q13813,O60476,Q9Y3B3,Q14789,P68371,O43237,Q9Y6Y8 33
Class a 1 rhodopsin like receptors 0.3040070730781027 0.0637261977088083 0.9491882443841028 1.0 1.0 7 Q9NZJ7,Q9NRV9 2
Peptide ligand binding receptors 0.3040070730781027 0.0637261977088083 0.9491882443841028 1.0 1.0 7 Q9NZJ7,Q9NRV9 2
Adherens junctions interactions 0.3119435212818507 0.0633981131629977 0.9494494897084476 1.0 1.0 6 P35221,P35222 2
Degradation of beta catenin by the destruction complex 0.3748701912087401 0.0614778183474008 0.9509786793798456 1.0 1.0 51 Q16537,P30154,Q13362,P49721,O00487,P62195,O43242,P17980,Q9UNM6,P28070,P28074,Q99436,P35222,P28072,P62191,P30153,Q15008,O00231,P48729,P25054,Q13616,Q9UL46,P25788,Q14738,Q06323,P61289,O75832,P43686 28
Cargo concentration in the er 0.2695739810504239 0.0546198033739573 0.9564413614973216 1.0 1.0 16 P49257 1
Formation of xylulose 5 phosphate 0.3812596006144285 0.0542537758610845 0.956732976795637 1.0 1.0 3 Q00796,Q7Z4W1 2
Gab1 signalosome 0.3720430107526772 0.0464274324353588 0.9629695721609686 1.0 1.0 3 Q06124,P62993 2
Semaphorin interactions 0.279771085962445 0.0448637800226039 0.9642158871142872 1.0 1.0 20 P35580,P35579,Q7Z406 3
Reproduction 0.2986171076613901 0.0441813264312752 0.9647598668664144 1.0 1.0 26 P11802,P02545,Q13472,P15927,P24941,P20700,Q9UH99,Q9UQE7 8
Meiosis 0.2986171076613901 0.0441813264312752 0.9647598668664144 1.0 1.0 26 P11802,P02545,Q13472,P15927,P24941,P20700,Q9UH99,Q9UQE7 8
Signaling by scf kit 0.2970401416858642 0.0383097632931939 0.9694407065196632 1.0 1.0 6 P40763,P62993,P42224 3
Aryl hydrocarbon receptor signalling 0.4917076167076231 0.0382933679654093 0.9694537785066868 1.0 1.0 2 Q15185 1
Mitotic g2 g2 m phases 0.4499878741143541 0.0351778535681582 0.9719379215917072 1.0 1.0 89 Q68CZ6,Q9BUF5,O95684,Q96CS2,P61163,P30154,P49721,Q13885,O94927,Q9BSJ2,Q14203,Q9H6D7,P28070,Q99436,Q99996,P41208,P07437,P28072,P30153,O00231,O75935,Q7Z4H7,Q9UL46,P04350,Q9BVA1,Q06323,P24941,Q15154,P61289,P68371,P62258 31
Leishmania infection 0.3347425821324832 0.0346263982717359 0.9723776513413028 1.0 1.0 39 Q7L576,P10644,P13861,P09601,Q9UQB8,O14641,Q9Y6W5,O43865,P35579 9
Signaling by ntrk3 trkc 0.3554531490015297 0.0345068658140925 0.972472967482358 1.0 1.0 3 P62993,Q07812 2
Generation of second messenger molecules 0.355453149001526 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q8N8S7,Q13177 2
Downstream signaling of activated fgfr1 0.3554531490015257 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr4 0.3554531490015257 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr2 0.3554531490015257 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q06124,P62993 2
Downstream signaling of activated fgfr3 0.3554531490015257 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q06124,P62993 2
Ret signaling 0.3554531490015257 0.0345068658140903 0.9724729674823598 1.0 1.0 3 Q06124,P62993 2
Transmission across chemical synapses 0.348760457935955 0.0344825727314072 0.9724923390295744 1.0 1.0 44 Q9BUF5,Q14168,P07196,P52292,Q9BVA1,P10644,P13861,Q13885,P21964,P68371,Q13136,P04350 12
Acyl chain remodelling of ps 0.4818796068796082 0.0342792010500178 0.9726545102787624 1.0 1.0 2 Q6P1A2 1
Pi3k akt signaling in cancer 0.2688163789663924 0.0328661345705844 0.9737813388956156 1.0 1.0 12 O43524 1
Regulation of ras by gaps 0.3310896360728958 0.0319648962766769 0.974500045296414 1.0 1.0 38 P28072,P49721,Q06323,O00231,P61289,P28070,Q9UL46 7
Signaling by egfr 0.2700858109698725 0.0317325856499513 0.9746853083744532 1.0 1.0 11 Q9UBC2,Q06124,P62993,P42566,Q9Y6I3 5
Sars cov 2 infection 0.297915050066857 0.0313675839538642 0.9749763926809528 1.0 1.0 27 Q8WUX9,P48729,Q8TBF4,Q10472,O43633 5
Erbb2 regulates cell motility 0.4726658476658534 0.0309968609447626 0.9752720430745908 1.0 1.0 2 O60610 1
Formation of incision complex in gg ner 0.2677003059555156 0.0300088190026771 0.9760600197923608 1.0 1.0 12 P41208 1
Retrograde neurotrophin signalling 0.2697181278337365 0.0285550519320477 0.977219460813628 1.0 1.0 9 Q9UQ16,P53680,P50570 3
Coenzyme a biosynthesis 0.4609950859950934 0.0274450090769083 0.9781047997025044 1.0 1.0 2 Q9NVE7 1
Tp53 regulates transcription of genes involved in cytochrome c release 0.4591523341523402 0.0269414280680282 0.978506450678252 1.0 1.0 2 P04637 1
Mitochondrial trna aminoacylation 0.2611027630346371 0.0266113315100499 0.978769735223168 1.0 1.0 16 Q9H2U2,Q9BW92,Q5JTZ9,Q9NSE4 4
Oncogenic mapk signaling 0.2964305987393472 0.026508876154042 0.9788514539409884 1.0 1.0 27 P02545,Q99956,Q6WCQ1,Q53H12,Q9NRY5,P51114,Q96PU8 7
Regulation of tp53 activity through methylation 0.4514742014742045 0.0249987140483715 0.980055989329903 1.0 1.0 2 P04637 1
Negative regulators of ddx58 ifih1 signaling 0.2872078720787234 0.0240448969076321 0.9808167964932264 1.0 1.0 6 Q7Z434,Q14258,P61086,Q96J02,Q15366 5
Cd209 dc sign signaling 0.4361179361179403 0.0217973091844173 0.9826096406379904 1.0 1.0 2 Q13177 1
Role of lat2 ntal lab on calcium mobilization 0.4361179361179387 0.0217973091844171 0.9826096406379904 1.0 1.0 2 P62993 1
Regulation of kit signaling 0.4361179361179387 0.0217973091844171 0.9826096406379904 1.0 1.0 2 P62993 1
P130cas linkage to mapk signaling for integrins 0.4241400491400631 0.0198478434316397 0.984164751848886 1.0 1.0 2 Q9Y490 1
Cobalamin cbl vitamin b12 transport and metabolism 0.3247715535693255 0.0188648905453392 0.9849488878398382 1.0 1.0 3 Q96EY8 1
Defects in cobalamin b12 metabolism 0.3247715535693255 0.0188648905453392 0.9849488878398382 1.0 1.0 3 Q96EY8 1
Protein ubiquitination 0.2838695277652286 0.0165767088347668 0.9867743056633418 1.0 1.0 24 P04439,P50542,O75150 3
Pd 1 signaling 0.371928746928747 0.015235689153881 0.987844149134706 1.0 1.0 2 Q06124 1
Resolution of abasic sites ap sites 0.2895735262479888 0.0146525558510761 0.9883093702362435 1.0 1.0 26 P15927,P41440,P56282,P49005 4
Signaling by fgfr4 in disease 0.355343980343977 0.014615160295737 0.9883392043778308 1.0 1.0 2 P62993 1
Synthesis of ip3 and ip4 in the cytosol 0.3553439803439803 0.014615160295737 0.9883392043778308 1.0 1.0 2 Q01968 1
Signalling to ras 0.3119715794223041 0.0143850773877026 0.9885227646793436 1.0 1.0 3 Q16539 1
Miscellaneous transport and binding events 0.2836508912108207 0.0143020735689015 0.988588985332426 1.0 1.0 4 Q9UEY8,Q9H0U3,P35612 3
Shc1 events in erbb2 signaling 0.3200245700245661 0.0139536655905692 0.9888669469362984 1.0 1.0 2 P62993 1
Met activates ptk2 signaling 0.3080466830466816 0.0138508288464914 0.9889489908578462 1.0 1.0 2 P11047 1
Ubiquinol biosynthesis 0.2800982800982715 0.0137286750597346 0.9890464462119204 1.0 1.0 2 O75208 1
Protein protein interactions at synapses 0.2591383201649697 0.0104613199235968 0.9916532265916748 1.0 1.0 17 Q14168,P41440,Q13136 3
Rhoc gtpase cycle 0.2936960200316336 0.0080714260795356 0.993560003672946 1.0 1.0 28 O75116,P41440,P42166,O75955,Q13464,P42167,P49257,Q13459,Q14739,Q9NSV4,Q8TAA9,Q07021,Q9H2G2 13
Metabolic disorders of biological oxidation enzymes 0.2734407373096171 0.0080191006257267 0.993601751993544 1.0 1.0 4 P48507 1
Signaling by pdgf 0.2699192616668492 0.0077296541712473 0.9938326896900946 1.0 1.0 7 P40763,P62993,P42224 3
Downstream signal transduction 0.2699192616668492 0.0077296541712473 0.9938326896900946 1.0 1.0 7 P40763,P62993,P42224 3
Phospholipid metabolism 0.3517293839210095 0.0075300105519691 0.9939919776148268 1.0 1.0 48 Q9NQZ5,P35790,Q53H12,Q8IV08,Q10713,Q96T51,Q8N2A8,Q9NPH0,Q9HBU6 9
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3509012498830188 0.0048150481848314 0.9961581622391092 1.0 1.0 48 P28072,Q96DE5,P49721,Q06323,O00231,P61289,P28070,Q99436,Q9UJX5,Q9UL46 10