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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +9 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/advanced/plot_0.png +3 -0
  11. interpro_binding_site/basic/idx2term.json +1 -0
  12. interpro_binding_site/basic/plot_0.png +3 -0
  13. interpro_binding_site/basic/plot_1.png +3 -0
  14. interpro_binding_site/consensus.joblib +3 -0
  15. interpro_binding_site/df_merge.tsv +2 -0
  16. interpro_binding_site/metrics.json +7 -0
  17. interpro_binding_site/paths.json +1 -0
  18. interpro_binding_site/result.tsv +6 -0
  19. interpro_binding_site/selections.json +1 -0
  20. interpro_conserved_site/advanced/idx2term.json +1 -0
  21. interpro_conserved_site/advanced/plot_0.png +3 -0
  22. interpro_conserved_site/advanced/plot_1.png +3 -0
  23. interpro_conserved_site/basic/idx2term.json +1 -0
  24. interpro_conserved_site/basic/plot_0.png +3 -0
  25. interpro_conserved_site/basic/plot_1.png +3 -0
  26. interpro_conserved_site/basic/plot_2.png +3 -0
  27. interpro_conserved_site/consensus.joblib +3 -0
  28. interpro_conserved_site/df_merge.tsv +3 -0
  29. interpro_conserved_site/metrics.json +7 -0
  30. interpro_conserved_site/paths.json +1 -0
  31. interpro_conserved_site/result.tsv +36 -0
  32. interpro_conserved_site/selections.json +1 -0
  33. interpro_domain/advanced/idx2term.json +1 -0
  34. interpro_domain/advanced/plot_0.png +3 -0
  35. interpro_domain/advanced/plot_1.png +3 -0
  36. interpro_domain/basic/idx2term.json +1 -0
  37. interpro_domain/basic/plot_0.png +3 -0
  38. interpro_domain/basic/plot_1.png +3 -0
  39. interpro_domain/basic/plot_10.png +3 -0
  40. interpro_domain/basic/plot_2.png +3 -0
  41. interpro_domain/basic/plot_3.png +3 -0
  42. interpro_domain/basic/plot_4.png +3 -0
  43. interpro_domain/basic/plot_5.png +3 -0
  44. interpro_domain/basic/plot_6.png +3 -0
  45. interpro_domain/basic/plot_7.png +3 -0
  46. interpro_domain/basic/plot_8.png +3 -0
  47. interpro_domain/basic/plot_9.png +3 -0
  48. interpro_domain/consensus.joblib +3 -0
  49. interpro_domain/df_merge.tsv +10 -0
  50. interpro_domain/metrics.json +7 -0
interpro_active_site/advanced/idx2term.json ADDED
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interpro_active_site/basic/idx2term.json ADDED
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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3258,
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+ "annotations_size": 55,
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+ "title": "Average number of proteins per term",
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+ "value": 2.709090909090909
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interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C270/C270_val_log2fc"}
interpro_active_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.7527641277641383 1.7039581336792602 0.0883889090664651 0.9938407473881442 0.1473148484441085 2 Q7LG56 1
3
+ Serine carboxypeptidase, serine active site [IPR018202] 0.8248847926267249 1.6559589400486068 0.0977301342099918 0.9965045353692462 0.1535759251871301 3 P10619,Q9HB40 2
4
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.6050314355735551 0.7619502206008589 0.446089714847921 0.9999999999999922 0.5984130321130647 3 Q9UBT2 1
5
+ ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.4769656019656118 0.481533369299491 0.6301374692818207 1.0 0.7876718366022758 2 P53396 1
6
+ Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.3964987714987777 0.2220432481651197 0.8242802163810192 1.0 0.9645832319352352 2 Q9NQ88 1
7
+ Glycosyl hydrolases family 31, active site [IPR030458] 0.2985257985257971 0.0536972268876594 0.9571763922392328 1.0 0.9883655412164584 2 P10253 1
8
+ Peptidase family C14A, His active site [IPR016129] 0.2890049140049067 0.0458244552427025 0.9634501668169552 1.0 0.9883655412164584 2 P55210 1
9
+ Peptidase family C14A, cysteine active site [IPR033139] 0.2890049140049067 0.0458244552427025 0.9634501668169552 1.0 0.9883655412164584 2 P55210 1
interpro_active_site/selections.json ADDED
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+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP7", "CDK1", "CDK11B", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPK9", "MARK2", "MASTL", "MDH1", "MDH2", "NEK9", "NME1", "NME3", "NME6", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACLY", "CASP7", "CTSA", "GAA", "RRM2B", "SCPEP1", "TIGAR", "UBA2"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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+ Beta tubulin, autoregulation binding site [IPR013838] 0.9532595325953228 2.6547709058576268 0.0079362286322652 0.2250621291885986 0.0230872105665899 6 P07437,Q13885,P68371,Q9BUF5,Q9BVA1 5
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+ Peptidase M16, zinc-binding site [IPR001431] 0.700228379894323 1.4166409263971058 0.1565879364593287 0.9957019261473736 0.2253546038246659 5 Q10713,O43847 2
5
+ Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.4241400491400487 0.3002601381932416 0.7639787362924237 1.0 0.814910652045252 2 P50579 1
6
+ PPM-type phosphatase, divalent cation binding [IPR000222] 0.3834101382488412 0.1056625389494809 0.915850103499796 1.0 0.945393655225596 3 Q9H0C8,P49593 2
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1"], "leading_proteins": ["CALU", "CAPNS1", "DST", "FKBP10", "FKBP14", "FKBP7", "ILKAP", "LETM1", "MACF1", "METAP2", "NRDC", "NUCB1", "NUCB2", "PMPCA", "PPM1F", "RCN2", "RHOT2", "SDF4", "SLC25A24", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "USP32"]}
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+ Tubulin, conserved site [IPR017975] 5 6 2.6547709058576268 0.0079362286322652 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 5.260528369818471e-07 0.0847528009868792 0.0006327439593496 2.765770662469611e-06 0.0001413957013589
3
+ Proteasome beta-type subunit, conserved site [IPR016050] 6 8 2.21371823158531 0.0268481679764545 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.1682230743467367 0.0479914252810258 0.0921025797166938 0.0231366382468947 5.383729574080712e-05
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3258,
4
+ "annotations_size": 280,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.7035714285714287
7
+ }
interpro_conserved_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C270/C270_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,36 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Tubulin, conserved site [IPR017975] 0.9532595325953226 2.6547709058576268 0.0079362286322652 0.8925799759858645 0.0249679103037559 6 P07437,Q13885,P68371,Q9BUF5,Q9BVA1 5
3
+ Haem oxygenase conserved site [IPR018207] 0.9603808353808356 2.616145184956576 0.0088928735837199 0.918008716129406 0.0262076343439782 2 P09601 1
4
+ Sterol reductase, conserved site [IPR018083] 0.95485257985258 2.59286683004159 0.009517961736269 0.9312853711886449 0.0271941763893401 2 Q14739 1
5
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.7847306335103772 2.21371823158531 0.0268481679764545 0.9995095787503068 0.0587547911031541 8 P20618,P28070,P28072,P49721,Q99436,P28074 6
6
+ Tetraspanin, conserved site [IPR018503] 0.961597542242703 2.201352965268538 0.027711045991412 0.9996174409187129 0.0597991701988686 3 Q9H1Z9,O60637 2
7
+ Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.8624078624078666 2.195099288398643 0.028156476259036 0.9996635065789689 0.0601817813170236 2 Q00796 1
8
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.953804642361844 2.170947105827918 0.0299351709553499 0.99979852901508 0.0630214125375787 3 Q8WWV3 1
9
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.701670072375569 1.81782984050742 0.069090144246994 0.9999999980314976 0.1174353440194663 8 Q9P2W9,O60499,O43752 3
10
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.7906125885376569 1.813023325530605 0.0698282237759193 0.9999999984235356 0.1177825461280567 5 O75874 1
11
+ Hexapeptide transferase, conserved site [IPR018357] 0.7493857493857571 1.6885465194500755 0.0913063669340115 0.9999999999977256 0.1412474184614542 2 Q9Y5P6 1
12
+ DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.6944103194103206 1.4362310247863126 0.1509366136084977 1.0 0.2123731246752732 2 P09884 1
13
+ Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.6722972972972974 1.3342675778074229 0.1821161792719003 1.0 0.2463407255851792 2 P01889 1
14
+ Ubiquitin specific protease, conserved site [IPR018200] 0.5353681718552997 1.3165044214532162 0.1880047953877499 1.0 0.2518724531510525 12 Q9UPU5,P51784,Q96RU2 3
15
+ Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842] 0.6191646191646217 1.0899736989561253 0.2757247298802967 1.0 0.3525247687967264 2 P60891 1
16
+ Thiosulphate sulfurtransferase, conserved site [IPR001307] 0.6121007371007421 1.0577380008519297 0.2901749053780282 1.0 0.3641995462088992 2 P25325 1
17
+ Clathrin adaptor complex, small chain [IPR000804] 0.6685099846390117 1.014965136105172 0.3101224468203813 1.0 0.3859301560431412 3 P61923,P61966 2
18
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.6632872503840193 0.9937783972408264 0.3203307655423195 1.0 0.3933886594379362 3 P26583,P09429 2
19
+ Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.6051528227487192 0.843727326380088 0.3988217938105118 1.0 0.4813366477023418 4 P28482 1
20
+ DnaJ domain, conserved site [IPR018253] 0.4701498689412859 0.8042474528031651 0.4212540784468204 1.0 0.5040647092526056 9 O60884,Q96KC8,Q9Y2G8 3
21
+ Dynamin, GTPase region, conserved site [IPR019762] 0.6097761180443304 0.7804282669416007 0.4351388350482814 1.0 0.5164717027514311 3 P50570 1
22
+ Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.5411547911548004 0.742080410421786 0.4580386179801727 1.0 0.5366142804788635 2 P29692 1
23
+ Malic enzyme, conserved site [IPR015884] 0.4803439803439914 0.4943162808265788 0.6210828288212291 1.0 0.6928414026691002 2 P48163 1
24
+ ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.4769656019656118 0.481533369299491 0.6301374692818207 1.0 0.6990348606485808 2 P53396 1
25
+ 14-3-3 protein, conserved site [IPR023409] 0.447109471094715 0.4263593610502028 0.6698460091393896 1.0 0.7355171865059965 6 P63104,Q04917,P62258,P61981,P27348 5
26
+ Oxysterol-binding protein, conserved site [IPR018494] 0.4809799714520438 0.3776037779607316 0.7057249577315203 1.0 0.7613566184669971 4 Q9BXB4 1
27
+ ABC transporter-like, conserved site [IPR017871] 0.357124707583512 0.3202331438149375 0.7487915999019383 1.0 0.7941729089869043 12 Q03518,P08183,P28288 3
28
+ Guanylate kinase, conserved site [IPR020590] 0.3849012723087656 0.2307410749811358 0.8175159612145086 1.0 0.8509459819333175 7 Q14168 1
29
+ Profilin conserved site [IPR027310] 0.395884520884523 0.2204526702684002 0.8255186292614036 1.0 0.8560933933081223 2 P07737 1
30
+ Phosphofructokinase, conserved site [IPR015912] 0.4353302611367031 0.2079709572520172 0.8352516442919451 1.0 0.8629906287887256 3 P08237,P17858 2
31
+ 4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.3442874692874657 0.1111952697318675 0.9114615025797874 1.0 0.932547809337392 2 P21912 1
32
+ Zinc finger, RING-type, conserved site [IPR017907] 0.3071831357360686 0.1098042227925108 0.912564641994448 1.0 0.932547809337392 12 P19474 1
33
+ Intermediate filament protein, conserved site [IPR018039] 0.3108401782900553 0.0633088408332679 0.9495205759207296 1.0 0.9667845863920156 8 P48681,P07196,P08670,P07197 4
34
+ Glycosyl hydrolases family 31, conserved site [IPR030459] 0.2985257985257971 0.0536972268876594 0.9571763922392328 1.0 0.9710485138658884 2 P10253 1
35
+ Thioredoxin, conserved site [IPR017937] 0.2843171926951067 0.0353989870259506 0.9717615924433324 1.0 0.9787526830364496 12 Q9H1E5,Q9H3N1,O95881,O43396 4
36
+ Ubiquitin interacting motif [IPR003903] 0.3085433312845762 0.0198110450527562 0.98419410693538 1.0 0.987721684379593 4 Q9Y6I3,P55036,Q92783 3
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDYL", "CETN2", "CHAF1B", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DBI", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMBP", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXO3", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ITGAV", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MAPK9", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PML", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX16", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP32", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCD3", "ACLY", "AP1S1", "COPZ1", "DNAJA2", "DNAJC1", "DNAJC16", "DNM2", "EEF1D", "EPN1", "GAA", "GMPPB", "HLA-B", "HMGB1", "HMGB2", "HMOX1", "IDH1", "LBR", "MAPK1", "ME1", "MPP2", "MPST", "NEFL", "NEFM", "NES", "OSBPL11", "PFKL", "PFKM", "PFN1", "POLA1", "PRPS1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD4", "RTN4IP1", "SDHB", "SORD", "STAM", "STX10", "STX18", "STX6", "TAP1", "TMX1", "TMX4", "TRIM21", "TSPAN10", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "TXNDC12", "TXNL1", "USP11", "USP24", "USP28", "VIM", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]"}
interpro_domain/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: 9cb10ff5fd2b4f73da0d4cc9aa07e46868b72b83d4995238fe67f6f48ec5f421
  • Pointer size: 131 Bytes
  • Size of remote file: 182 kB
interpro_domain/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 41e308b59d63e08edb9bf07103b634c2dad741fd2318bd407f0ac6975f8a2d13
  • Pointer size: 131 Bytes
  • Size of remote file: 183 kB
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "Importin-beta, N-terminal domain [IPR001494]", "3": "Ubiquitin-associated domain [IPR015940]", "4": "EF-hand domain [IPR002048]", "5": "Proteasome component (PCI) domain [IPR000717]", "6": "K Homology domain, type 1 [IPR004088]", "7": "14-3-3 domain [IPR023410]", "8": "TGS [IPR004095]", "9": "Glutathione S-transferase, C-terminal-like [IPR010987]", "10": "Glutathione S-transferase, C-terminal [IPR004046]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 141 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

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  • Size of remote file: 146 kB
interpro_domain/basic/plot_10.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 142 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 138 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_domain/basic/plot_4.png ADDED

Git LFS Details

  • SHA256: 3ea113e826dbf34ec349cba262ab47a2a36df4d42085042b04845f52093e2156
  • Pointer size: 131 Bytes
  • Size of remote file: 137 kB
interpro_domain/basic/plot_5.png ADDED

Git LFS Details

  • SHA256: 502a2423589a34df9b9939a88bdc756a69d7e05c6712ae4e475c72c72dab976a
  • Pointer size: 131 Bytes
  • Size of remote file: 152 kB
interpro_domain/basic/plot_6.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 149 kB
interpro_domain/basic/plot_7.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 122 kB
interpro_domain/basic/plot_8.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 127 kB
interpro_domain/basic/plot_9.png ADDED

Git LFS Details

  • SHA256: 9c6177b073bb53ca546cef6a61f9bd8f784e0ca4d9f9702775c18372e1f61275
  • Pointer size: 131 Bytes
  • Size of remote file: 151 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:7f85c40207891170bbedbdf350ac673106f1fd5c53ec16c54ad1961790612479
3
+ size 706304
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,10 @@
 
 
 
 
 
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Tubulin/FtsZ, GTPase domain [IPR003008] 5 6 2.6547709058576268 0.0079362286322652 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 5.260528369818471e-07 0.0847528009868792 0.0006327439593496 2.765770662469611e-06 0.0001413957013589
3
+ Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 5 6 2.6547709058576268 0.0079362286322652 3.6140776699029127 5.883495145631068 0.537603280896448 0.3771225437200781 1.6631634011190108 1.117390952728082 1.2199662970774952 0.3090115161057067 3.5607901969703626e-07 0.0802348466038066 0.0005309775927247 1.8818469985730976e-06 9.825976589410204e-05
4
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 4 6 2.541498243713184 0.0110378500750343 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 7.089439467684663e-06 0.0385773062479974 0.0743799864466655 4.228937316679017e-07 1.2976991690069218e-05
5
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 4 6 2.541498243713184 0.0110378500750343 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 7.089439467684663e-06 0.0385773062479974 0.0743799864466655 4.228937316679017e-07 1.2976991690069218e-05
6
+ Polyketide synthase, enoylreductase domain [IPR020843] 3 6 2.345413434474917 0.0190059914665516 1.6189320388349515 6.283980582524272 0.4837477775906041 0.3583565743712875 1.2357658783365448 1.1656223303878015 1.2317099658487027 0.2921137785685181 0.0008848372099536 0.0526645480715484 0.0047533286028597 9.701143498590324e-05 0.0013678067399173
7
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 6 2.258046397482075 0.0239427669397143 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0193723615965321 1.0 0.0056684159955205 0.00262770885776 0.0019736987849612
8
+ Major facilitator superfamily domain [IPR020846] 4 7 2.112704682712999 0.0346260522526207 1.8883495145631068 4.121359223300971 0.8776223597987594 0.2728824130413255 1.233496960525634 1.4580976091979958 1.2936014196902064 0.266909732326598 0.0168922283757233 1.0 1.0 0.0352396407582777 0.0136556200878641
9
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 4 5 2.0891340974478685 0.0366956537519742 1.691747572815534 3.3592233009708736 1.3447142040916915 0.1822595206051251 1.014281444620711 0.9789470163478144 1.2723870690026748 0.2262567589818981 0.0006522488756469 0.0479914252810258 0.0921025797166938 6.292953854873037e-05 5.383729574080712e-05
10
+ Alcohol dehydrogenase, N-terminal [IPR013154] 3 5 2.064626673738212 0.0389583374274802 1.3762135922330097 5.245145631067961 0.6000738304798152 0.3870290227769069 1.1994000251783288 0.9246362329357484 1.1062357688130569 0.3020782188917261 0.010952878324973 0.0432957136582515 0.0031504918831051 0.0010588751859522 0.0005644670723367
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3258,
4
+ "annotations_size": 2644,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.18910741301059
7
+ }