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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +1 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +6 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/advanced/plot_0.png +3 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +3 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +28 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
- interpro_domain/basic/plot_4.png +3 -0
- interpro_domain/basic/plot_5.png +3 -0
- interpro_domain/basic/plot_6.png +3 -0
- interpro_domain/basic/plot_7.png +3 -0
- interpro_domain/basic/plot_8.png +3 -0
- interpro_domain/basic/plot_9.png +3 -0
- interpro_domain/consensus.joblib +3 -0
- interpro_domain/df_merge.tsv +9 -0
- interpro_domain/metrics.json +7 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{}
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:411b0fe2dffd196989a461eb7ec03791027a89e19b37b456a3389f32b78ab3e3
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size 71506
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2719,
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"annotations_size": 51,
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"title": "Average number of proteins per term",
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"value": 2.450980392156863
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C274/C274_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CAPN2", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKACA", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": []}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/consensus.joblib
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oid sha256:5db856888671dd4a86ec4f77b887499a332b7a4adfabfd255bf0b59425429571
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size 66424
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2719,
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"annotations_size": 30,
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"title": "Average number of proteins per term",
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"value": 4.166666666666667
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C274/C274_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.8365844681634174 2.397321150802186 0.0165154413720247 0.3932268318925999 0.0340286792261927 2 P34897 1
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Peptidase M16, zinc-binding site [IPR001431] 0.660057464688079 1.576104314364473 0.1150017649332408 0.9743981034826428 0.1815817341051172 5 Q10713,O75439,P22695 3
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Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.4092749355907346 0.4682979011376147 0.6395715691646995 0.9999999999999494 0.7379671951900378 2 O75600 1
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Beta tubulin, autoregulation binding site [IPR013838] 0.3604865462587538 0.2345514601633529 0.814556887710449 1.0 0.8727395225469096 6 P07437,P68371,P04350,Q13885,Q9BUF5 5
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.2922340817077751 0.0914113552752935 0.9271657393218478 1.0 0.9591369717122564 2 Q9H0C8 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "BPNT1", "CALM3", "CALU", "CAPN1", "CAPN2", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15L1", "FKBP10", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["GCAT", "ILKAP", "PMPCA", "PMPCB", "SHMT2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2"]}
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interpro_conserved_site/advanced/idx2term.json
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}
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interpro_conserved_site/advanced/plot_0.png
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interpro_conserved_site/basic/idx2term.json
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{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Thioredoxin, conserved site [IPR017937]", "2": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "3": "Tubulin, conserved site [IPR017975]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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interpro_conserved_site/basic/plot_2.png
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interpro_conserved_site/basic/plot_3.png
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:9a3b0eefa1a00e66f64bc43f3d4845d0cd62305aad75ca88f102ce9b3d5838d6
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size 103930
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Proteasome beta-type subunit, conserved site [IPR016050] 6 8 2.399439357570335 0.0164201993969199 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0470522829573702 0.0921025797166938 3.77413242971045e-08 6.717153209388309e-08
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Intermediate filament protein, conserved site [IPR018039] 4 8 1.9739925780788703 0.0483825868761802 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.3582816735878424 0.0013736729067174
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 2719,
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"annotations_size": 256,
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"title": "Average number of proteins per term",
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"value": 2.55859375
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}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C274/C274_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Guanylate kinase, conserved site [IPR020590] 0.8965009208103073 2.6307880630503964 0.0085187141513689 0.8880980996409711 0.0454331421406344 4 Q9NZW5,Q14168,O14936 3
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Haem oxygenase conserved site [IPR018207] 0.8616120721383891 2.502884554817699 0.0123185718462912 0.9581280462858472 0.0543716274594924 2 P30519 1
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Proteasome beta-type subunit, conserved site [IPR016050] 0.8469707402230665 2.399439357570335 0.0164201993969199 0.9855702797142591 0.0593613591660233 8 P28070,Q99436,P28074,P20618,P28072,P49721 6
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Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.8395565149173263 2.3906403955082216 0.016819017314871 0.9869932675482164 0.0593613591660233 4 P48735 1
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| 6 |
+
Chromo domain, conserved site [IPR023779] 0.7713197772831922 2.093557601821134 0.0362994077750955 0.9999225209613888 0.097410946550186 4 Q13185,P83916 2
|
| 7 |
+
Intermediate filament protein, conserved site [IPR018039] 0.7514976031716787 1.9739925780788703 0.0483825868761802 0.9999969354312366 0.1106232732097935 8 P07197,P20700,Q03252,P08670 4
|
| 8 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.7296738047023092 1.918875943779893 0.0550000357525046 0.9999994865019814 0.1173334096053433 3 Q16836 1
|
| 9 |
+
Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.6981285629812294 1.7343588338435407 0.0828544344630488 0.9999999997577872 0.1521395188378595 7 P05091,P51649,P30837 3
|
| 10 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.6761296954839143 1.6318085885602136 0.1027198154828872 0.9999999999991096 0.1801114572850625 7 P19474 1
|
| 11 |
+
Thioredoxin, conserved site [IPR017937] 0.5787629469666136 1.1440535199720971 0.2526014420461506 1.0 0.3233298458190728 10 O95881,Q8IXB1,O43396,Q9H3N1,P07237 5
|
| 12 |
+
DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.5163783584836292 0.9432928936110192 0.3455311097528228 1.0 0.3978848075977614 2 O15160 1
|
| 13 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.5110456553755538 0.9030745899186156 0.3664863089239352 1.0 0.4151349340023336 3 Q9Y2T2,Q9BXS5 2
|
| 14 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.5135118914463082 0.8716326075993119 0.38340883606257 1.0 0.428614244681301 6 P49736 1
|
| 15 |
+
Annexin repeat, conserved site [IPR018252] 0.4877641771281426 0.7523857863064463 0.4518190917749791 1.0 0.5007172618804964 6 P09525 1
|
| 16 |
+
IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.4405594405594469 0.5999835905904339 0.5485171715919557 1.0 0.6026626434658398 2 P20839 1
|
| 17 |
+
Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.4447955651999828 0.549078114492064 0.5829518437564243 1.0 0.6377592820583103 7 P05091,P51649,P30837 3
|
| 18 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.4089068825911003 0.4668017994815134 0.6406416882879313 1.0 0.6978905200072784 2 Q13363 1
|
| 19 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.4281553255297695 0.419441428487692 0.6748935521902402 1.0 0.7289989424502172 13 Q92620,O43143,Q9H2U1,Q08211,O60231,O94762,Q14562,Q7Z478 8
|
| 20 |
+
ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.4293717669972567 0.3809431008271222 0.7032454696243571 1.0 0.7532671139072611 19 Q9UHI6,Q8N8A6,P17844,Q92841 4
|
| 21 |
+
ABC transporter-like, conserved site [IPR017871] 0.3971838119381105 0.3335875071053839 0.7386908466552411 1.0 0.7846674553682229 9 O75027,Q9NUQ8,P08183 3
|
| 22 |
+
Kinesin motor domain, conserved site [IPR019821] 0.3930899559966166 0.2900552995476271 0.7717739321760542 1.0 0.809730027201106 12 Q9NQT8 1
|
| 23 |
+
Tubulin, conserved site [IPR017975] 0.3604865462587538 0.2345514601633529 0.814556887710449 1.0 0.8476689563165648 6 P07437,P68371,P04350,Q13885,Q9BUF5 5
|
| 24 |
+
DNA ligase, ATP-dependent, conserved site [IPR016059] 0.3323518586676566 0.1941143418154126 0.8460863520703674 1.0 0.8689308309303633 2 P18858 1
|
| 25 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.3323442653151932 0.1226146264559905 0.9024122716087036 1.0 0.9147132002947412 9 Q96K76,Q9UPU5 2
|
| 26 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.3134438305709098 0.1206176288628431 0.9039939049787872 1.0 0.9147132002947412 4 Q13363,P56545,O43175 3
|
| 27 |
+
DnaJ domain, conserved site [IPR018253] 0.3202578334103335 0.1003241715713413 0.9200869681597408 1.0 0.9273317474365892 8 Q99543,Q96KC8,P31689 3
|
| 28 |
+
Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.2569955817378521 0.0209158827877462 0.9833127567632314 1.0 0.9871688852211264 3 Q16539,P28482 2
|
interpro_conserved_site/selections.json
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB6", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPDR1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KATNB1", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LARS", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB2", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIN1", "PLEC", "PLOD1", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCF3", "ALDH1B1", "ALDH2", "ALDH5A1", "ANXA4", "AP1M1", "AP3M1", "CASK", "CBX1", "CBX3", "CTBP1", "CTBP2", "DDX17", "DDX20", "DDX5", "DDX51", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DNAJA1", "DNAJC1", "DNAJC10", "DNAJC2", "HADH", "HMOX2", "IDH2", "IMPDH1", "KIF13B", "LIG1", "LMNB1", "LMNB2", "MAPK1", "MAPK14", "MCM2", "MPP2", "MPP6", "NEFM", "P4HB", "PHGDH", "POLR1C", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "RECQL5", "TMX1", "TRIM21", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNL1", "USP24", "USP47", "VIM"]}
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interpro_domain/advanced/idx2term.json
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{"0": "RNA recognition motif domain [IPR000504]"}
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interpro_domain/advanced/plot_0.png
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interpro_domain/basic/idx2term.json
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{"0": "RNA recognition motif domain [IPR000504]", "1": "G-patch domain [IPR000467]", "2": "K Homology domain, type 1 [IPR004088]", "3": "K Homology domain [IPR004087]", "4": "Tudor domain [IPR002999]", "5": "PDZ domain [IPR001478]", "6": "Helicase-associated domain [IPR007502]", "7": "Domain of unknown function DUF1605 [IPR011709]", "8": "DnaJ domain [IPR001623]", "9": "RNA-binding domain, S1 [IPR022967]", "10": "S1 domain [IPR003029]", "11": "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "12": "Tubulin/FtsZ, GTPase domain [IPR003008]", "13": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]"}
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interpro_domain/basic/plot_1.png
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interpro_domain/basic/plot_10.png
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interpro_domain/basic/plot_11.png
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interpro_domain/basic/plot_12.png
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interpro_domain/basic/plot_13.png
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interpro_domain/basic/plot_2.png
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interpro_domain/basic/plot_3.png
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interpro_domain/basic/plot_5.png
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interpro_domain/basic/plot_6.png
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interpro_domain/basic/plot_7.png
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interpro_domain/basic/plot_8.png
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interpro_domain/basic/plot_9.png
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interpro_domain/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:5e3f6e3dc36efca925e6f2582bb5ec2c4a95a188102cd430622916e0f1573be9
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size 485386
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interpro_domain/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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| 2 |
+
RNA recognition motif domain [IPR000504] 40 108 4.655562380025966 3.230975608836673e-06 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 1.0 0.0508202511523996 1.0125487367068977e-08 7.646827374385677e-14 1.6674649533530572e-18
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| 3 |
+
Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 6 2.6571535739867653 0.0078803535474489 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0003168921885558 2.2261381171916983e-05 0.0001778916397324 5.632723326964323e-06 0.0001620848202149
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| 4 |
+
Zinc finger, RanBP2-type [IPR001876] 4 8 2.224913479508802 0.0260870469451679 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 1.0 1.0 0.0010099703116007 0.0136772183990335 0.0028896459807526
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| 5 |
+
LEM domain [IPR003887] 4 6 2.213983217962729 0.0268299334006427 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 1.0 1.0 0.0563150378970086 0.0002693258491638 1.5702078168631558e-06
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| 6 |
+
Guanylate kinase-like domain [IPR008144] 3 6 2.2088646889809582 0.0271840539222694 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 0.1349531130589082 0.005208827916976 0.004988841333209
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| 7 |
+
Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 3 6 2.2088646889809582 0.0271840539222694 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 0.1596960736798767 0.0088528623379573 0.0099569143851569
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| 8 |
+
FAD/NAD(P)-binding domain [IPR023753] 0 5 2.181590442772832 0.0291397728671056 1.305825242718447 4.980582524271845 0.3254034663776002 0.5017462024465073 1.2360542642688364 0.4721482103218573 0.9364120623905048 0.2987345213731214 0.0245475710802424 0.0516364610584135 0.1008375048293403 0.2373820829012167 0.4236908718837023
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| 9 |
+
Intermediate filament, rod domain [IPR039008] 4 8 1.9739925780788703 0.0483825868761802 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.4185863086244521 0.0035916782285116
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interpro_domain/metrics.json
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{
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| 2 |
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"type_of_task": "ranksum",
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| 3 |
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"signature_size": 2719,
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| 4 |
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"annotations_size": 2332,
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| 5 |
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"title": "Average number of proteins per term",
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| 6 |
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"value": 2.0806174957118353
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| 7 |
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}
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