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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +6 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/basic/plot_0.png +3 -0
  12. interpro_binding_site/consensus.joblib +3 -0
  13. interpro_binding_site/df_merge.tsv +1 -0
  14. interpro_binding_site/metrics.json +7 -0
  15. interpro_binding_site/paths.json +1 -0
  16. interpro_binding_site/result.tsv +7 -0
  17. interpro_binding_site/selections.json +1 -0
  18. interpro_conserved_site/advanced/idx2term.json +1 -0
  19. interpro_conserved_site/basic/idx2term.json +1 -0
  20. interpro_conserved_site/basic/plot_0.png +3 -0
  21. interpro_conserved_site/consensus.joblib +3 -0
  22. interpro_conserved_site/df_merge.tsv +1 -0
  23. interpro_conserved_site/metrics.json +7 -0
  24. interpro_conserved_site/paths.json +1 -0
  25. interpro_conserved_site/result.tsv +24 -0
  26. interpro_conserved_site/selections.json +1 -0
  27. interpro_domain/advanced/idx2term.json +1 -0
  28. interpro_domain/basic/idx2term.json +1 -0
  29. interpro_domain/basic/plot_0.png +3 -0
  30. interpro_domain/basic/plot_1.png +3 -0
  31. interpro_domain/basic/plot_10.png +3 -0
  32. interpro_domain/basic/plot_11.png +3 -0
  33. interpro_domain/basic/plot_2.png +3 -0
  34. interpro_domain/basic/plot_3.png +3 -0
  35. interpro_domain/basic/plot_4.png +3 -0
  36. interpro_domain/basic/plot_5.png +3 -0
  37. interpro_domain/basic/plot_6.png +3 -0
  38. interpro_domain/basic/plot_7.png +3 -0
  39. interpro_domain/basic/plot_8.png +3 -0
  40. interpro_domain/basic/plot_9.png +3 -0
  41. interpro_domain/consensus.joblib +3 -0
  42. interpro_domain/df_merge.tsv +4 -0
  43. interpro_domain/metrics.json +7 -0
  44. interpro_domain/paths.json +1 -0
  45. interpro_domain/result.tsv +202 -0
  46. interpro_domain/selections.json +0 -0
  47. interpro_family/advanced/idx2term.json +1 -0
  48. interpro_family/basic/idx2term.json +1 -0
  49. interpro_family/basic/plot_0.png +3 -0
  50. interpro_family/basic/plot_1.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {}
interpro_active_site/consensus.joblib ADDED
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+ size 60235
interpro_active_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2719,
4
+ "annotations_size": 51,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.450980392156863
7
+ }
interpro_active_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C276/C276_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,6 @@
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine carboxypeptidase, serine active site [IPR018202] 0.9510309278350516 1.948317638065544 0.0513769679514899 0.9321145175664812 0.4781142883855629 3 Q9H3G5,Q9HB40 2
3
+ Histidine acid phosphatase active site [IPR033379] 0.9252852410747152 1.2643927555818952 0.2060890917953246 0.9999922667824992 0.4909958596169929 2 Q9NPH0 1
4
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.4862237318825198 0.6367670715597841 0.5242765776923579 1.0 0.8102456200700077 6 Q06124 1
5
+ Cysteine peptidase, cysteine active site [IPR000169] 0.405985000079467 0.2532959565773714 0.8000395204379576 1.0 0.9488840823799032 4 P07384 1
6
+ Peptidase S9, serine active site [IPR002471] 0.3599558336400521 0.029088722951933 0.9767938297741884 1.0 0.9767938297741884 2 P48147 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAPN1", "CAPN2", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKACA", "PTK2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CAPN1", "CPVL", "PREP", "PTPN11", "SCPEP1"]}
interpro_binding_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
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+ {}
interpro_binding_site/basic/idx2term.json ADDED
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+ {"0": "Beta tubulin, autoregulation binding site [IPR013838]"}
interpro_binding_site/basic/plot_0.png ADDED

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interpro_binding_site/consensus.joblib ADDED
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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 2719,
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+ "annotations_size": 30,
5
+ "title": "Average number of proteins per term",
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+ "value": 4.166666666666667
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+ }
interpro_binding_site/paths.json ADDED
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1
+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C276/C276_val_log2fc"}
interpro_binding_site/result.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Biotin-binding site [IPR001882] 0.7491002112617087 1.514605490292333 0.1298723409901776 0.9846011170532288 0.7284531886602095 4 P05165,Q96RQ3 2
3
+ Beta tubulin, autoregulation binding site [IPR013838] 0.6723184666420852 1.4329925843759317 0.1518599565652023 0.9928545917970651 0.7284531886602095 6 Q9BVA1,P04350,Q9BUF5,Q13885,P07437 5
4
+ Peptidase M16, zinc-binding site [IPR001431] 0.5579023382960809 0.8434238808224519 0.3989914206494684 0.9999997675015044 0.7601776714537772 5 Q10713,O43847 2
5
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.6886271623113773 0.4495185726105727 0.6530576132759347 0.999999999999984 0.8966830398434664 2 P34897 1
6
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4804438319140889 0.2557583845451542 0.7981374096458 1.0 0.8966830398434664 34 P80303,Q14257,Q15293 3
7
+ Hexokinase, binding site [IPR019807] 0.5322046374678027 0.1222523501194509 0.9026991679423388 1.0 0.9026991679423388 2 P52789 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "BPNT1", "CALM3", "CALU", "CAPN1", "CAPN2", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15L1", "FKBP10", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "LETM1", "MACF1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["HK2", "MCCC1", "NRDC", "NUCB2", "PCCA", "PMPCA", "RCN1", "RCN2", "SHMT2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ {}
interpro_conserved_site/basic/idx2term.json ADDED
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1
+ {"0": "Tubulin, conserved site [IPR017975]"}
interpro_conserved_site/basic/plot_0.png ADDED

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interpro_conserved_site/consensus.joblib ADDED
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interpro_conserved_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2719,
4
+ "annotations_size": 256,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.55859375
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C276/C276_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Tetraspanin, conserved site [IPR018503] 0.9238795614879136 1.8472467490047584 0.0647113867978559 0.9999999635174126 0.7875475118861395 3 O43657 1
3
+ Guanylate kinase, conserved site [IPR020590] 0.7937290084010185 1.6908385041924603 0.0908676510203698 0.9999999999743824 0.7875475118861395 4 Q14168,Q9NZW5 2
4
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.7406634827037195 1.6866040452431124 0.0916795136097792 0.9999999999796196 0.7875475118861395 8 P20618,P28074,P49721 3
5
+ Sterol reductase, conserved site [IPR018083] 0.9963194700036804 1.5312835829579086 0.1256993211779402 0.9999999999999988 0.7875475118861395 2 Q9UBM7 1
6
+ Tubulin, conserved site [IPR017975] 0.6723184666420852 1.4329925843759317 0.1518599565652023 1.0 0.7875475118861395 6 Q9BVA1,P04350,Q9BUF5,Q13885,P07437 5
7
+ EGF-like calcium-binding, conserved site [IPR018097] 0.9227088700772916 1.2547536482244497 0.2095682038309836 1.0 0.8355843060043376 2 Q07954 1
8
+ Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9175561280824442 1.2354911605251988 0.2166477642377602 1.0 0.8355843060043376 2 Q9BTY2 1
9
+ Haem oxygenase conserved site [IPR018207] 0.8954729481045277 1.1532235873232597 0.2488186244270103 1.0 0.8507112236288034 2 P30519 1
10
+ Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.5661211916735979 0.957813343335424 0.3381568895151279 1.0 0.9495743198362598 7 P30837 1
11
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.6083588257801 0.953349415140089 0.3404130620946741 1.0 0.9495743198362598 4 P48735 1
12
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.6719112113456203 0.8926262099856208 0.3720573783400738 1.0 0.962087766212716 3 O15347 1
13
+ DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.5213618742688313 0.6735966492938421 0.5005677840078788 1.0 0.9707981265607348 13 Q14562,Q9H2U1,P18074 3
14
+ AMP-binding, conserved site [IPR020845] 0.4635224760501161 0.4771084950637315 0.6332848657647121 1.0 1.0 5 O95573,Q4G176,Q6P1M0,P33121 4
15
+ Ribosomal protein L3, conserved site [IPR019926] 0.6323150533676903 0.3025862355537492 0.7622052054526367 1.0 1.0 2 P39023 1
16
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4845360824742286 0.287583842976693 0.7736653140712322 1.0 1.0 3 P42345,P78527 2
17
+ Ribosomal protein L30, conserved site [IPR018038] 0.6083916083916143 0.2495112705429417 0.8029653239071657 1.0 1.0 2 P18124 1
18
+ Zinc finger, RING-type, conserved site [IPR017907] 0.3662616943723401 0.1913131241669148 0.8482802793983188 1.0 1.0 7 O15164,P38398,P19474 3
19
+ Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.3575680542644472 0.1667091381696344 0.8675989149443453 1.0 1.0 7 P30837 1
20
+ Thioredoxin, conserved site [IPR017937] 0.3535251025241901 0.1284768535652562 0.8977716145867802 1.0 1.0 10 O95881 1
21
+ RNA polymerase, beta subunit, conserved site [IPR007121] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 1.0 2 P30876 1
22
+ Ubiquitin interacting motif [IPR003903] 0.4895104895104976 0.0783371964278422 0.937559829890366 1.0 1.0 2 Q92783 1
23
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.343519882179678 0.0603095898039053 0.9519090642916216 1.0 1.0 3 Q9Y2T2,Q96CW1 2
24
+ ABC transporter-like, conserved site [IPR017871] 0.3115472289313566 0.0436623355908581 0.96517356241236 1.0 1.0 9 P08183 1
interpro_conserved_site/selections.json ADDED
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1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB6", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAP2", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC1", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPDR1", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KATNB1", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "LAMP1", "LARS", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NFKB2", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIN1", "PLEC", "PLOD1", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP24", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ACSF3", "ACSL1", "ACSL3", "ALDH1B1", "AP2M1", "AP3M1", "BRCA1", "DHCR7", "DHX36", "DHX8", "ERCC2", "FUCA2", "HMGB3", "HMOX2", "IDH2", "LRP1", "MPP2", "MPP6", "MTOR", "POLR2B", "PRKDC", "PSMB1", "PSMB2", "PSMB5", "RPL3", "RPL7", "SLC27A4", "STAM", "TRIM21", "TRIM24", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB6", "TXNDC12"]}
interpro_domain/advanced/idx2term.json ADDED
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1
+ {}
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "High mobility group box domain [IPR009071]", "3": "GOLD domain [IPR009038]", "4": "Chromo/chromo shadow domain [IPR000953]", "5": "Myosin head, motor domain [IPR001609]", "6": "PDZ domain [IPR001478]", "7": "S1 domain [IPR003029]", "8": "RNA-binding domain, S1 [IPR022967]", "9": "Importin-beta, N-terminal domain [IPR001494]", "10": "SH3 domain [IPR001452]", "11": "K Homology domain, type 1 [IPR004088]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 414d4102223ecfefebdd990dcf36ee03e7652d3d9cb473df17c4710cf732892d
  • Pointer size: 131 Bytes
  • Size of remote file: 133 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 29f58b353673197f060d17ba410f09b7620f827a26fdbf4f276c0404d7e8ae4b
  • Pointer size: 131 Bytes
  • Size of remote file: 138 kB
interpro_domain/basic/plot_10.png ADDED

Git LFS Details

  • SHA256: 1e9d53f1e9d00972cead0cebcd9dfe7b8841233dbeffd97beae1d7baf86bf666
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB
interpro_domain/basic/plot_11.png ADDED

Git LFS Details

  • SHA256: 2e82f5217fe6683bc17be885c4a85e8213239bea95f4d9b003a014c087abb37a
  • Pointer size: 131 Bytes
  • Size of remote file: 149 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 9f59c475982e14b9cf91c1d5172b4915d56e7a703a126d30c939128bf2671fa5
  • Pointer size: 131 Bytes
  • Size of remote file: 137 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: 99e7e7c0581372a637fe7726b8054a8561e002c581b3b4f64c41376b4647f99f
  • Pointer size: 131 Bytes
  • Size of remote file: 130 kB
interpro_domain/basic/plot_4.png ADDED

Git LFS Details

  • SHA256: b220493bd8b68b441650c36576c1d166c3a41112cb4f486ee3862710bede5e42
  • Pointer size: 131 Bytes
  • Size of remote file: 139 kB
interpro_domain/basic/plot_5.png ADDED

Git LFS Details

  • SHA256: 908118c2065e3ee5d5a23397f0c179054cd2f28e52c24e526a16fd13b6f48eaf
  • Pointer size: 131 Bytes
  • Size of remote file: 134 kB
interpro_domain/basic/plot_6.png ADDED

Git LFS Details

  • SHA256: e54bb79fd6c67c0dfdb7650c4559698ed06575e8d8505820b4a435bcf0a58808
  • Pointer size: 131 Bytes
  • Size of remote file: 140 kB
interpro_domain/basic/plot_7.png ADDED

Git LFS Details

  • SHA256: 5922ea2c5f65fa950c37c0dce1a5a37411439327605110feee6a7446c63c0d86
  • Pointer size: 131 Bytes
  • Size of remote file: 130 kB
interpro_domain/basic/plot_8.png ADDED

Git LFS Details

  • SHA256: a22e0c63d586598ff1ae53ea98ba4e680dab105156d2a6d2b86fd2cd9fc7c6a4
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_domain/basic/plot_9.png ADDED

Git LFS Details

  • SHA256: b89011585195aee360be848596c9227c1f2cc15a39b5de8544eb53d5d537457d
  • Pointer size: 131 Bytes
  • Size of remote file: 146 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:50b568864cb608d6301e3ba576dc1db4741979fa0518762224244e0cce4e63a9
3
+ size 92921
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Alcohol dehydrogenase, N-terminal [IPR013154] 0 6 2.0377886898303963 0.0415710699556359 1.3762135922330097 5.245145631067961 0.6000738304798152 0.3870290227769069 1.1994000251783288 0.9246362329357484 1.1062357688130569 0.3020782188917261 0.0035266423776777 0.0424464003246627 0.0824659877424542 0.1937573006043177 0.0658357498291143
3
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 2 5 2.003841833226931 0.0450870060376487 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 1.0 0.0378187125466048 0.0024164244761899 0.0141813596379722 0.005094370489711
4
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 2 5 2.003841833226931 0.0450870060376487 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 1.0 0.0378187125466048 0.0024164244761899 0.0141813596379722 0.005094370489711
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2719,
4
+ "annotations_size": 2332,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.0806174957118353
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C276/C276_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,202 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8415688802043391 2.003841833226931 0.0450870060376487 1.0 0.7926277900753033 5 Q9UIQ6,P55786 2
3
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8415688802043391 2.003841833226931 0.0450870060376487 1.0 0.7926277900753033 5 Q9UIQ6,P55786 2
4
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7837739987730088 1.9011447519178537 0.0572830552614991 1.0 0.7926277900753033 6 Q8WUJ1 1
5
+ GMP phosphodiesterase, delta subunit [IPR008015] 0.9274668630338736 1.8606464236424691 0.062794124401508 1.0 0.7926277900753033 3 O43924,A6NIH7 2
6
+ CBS domain [IPR000644] 0.8345084746731173 1.849855686672325 0.0643343522116177 1.0 0.7926277900753033 4 P51790 1
7
+ EGF-like domain [IPR000742] 0.9123172063888532 1.8039667041043776 0.0712365267818735 1.0 0.7926277900753033 3 Q07954 1
8
+ ERAP1-like C-terminal domain [IPR024571] 0.9009572901325482 1.7613137864729835 0.0781853079025687 1.0 0.7926277900753033 3 Q9UIQ6,P55786 2
9
+ Guanylate kinase-like domain [IPR008144] 0.7493758700910876 1.758808359785695 0.0786100643920215 1.0 0.7926277900753033 6 Q00013,Q14168,Q9NZW5 3
10
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.7493758700910876 1.758808359785695 0.0786100643920215 1.0 0.7926277900753033 6 Q00013,Q14168,Q9NZW5 3
11
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.8030186865496022 1.7272470072840118 0.084123311883975 1.0 0.7926277900753033 4 P13674,Q32P28 2
12
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.8030186865496022 1.7272470072840118 0.084123311883975 1.0 0.7926277900753033 4 P13674,Q32P28 2
13
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.879970544918999 1.682197792035747 0.092530492141128 1.0 0.7926277900753033 3 P52888,Q9BYT8 2
14
+ MRH domain [IPR044865] 0.8788063023401818 1.6777975153723337 0.0933866345735818 1.0 0.7926277900753033 3 P11717 1
15
+ SET domain [IPR001214] 0.723857222032619 1.651906021957854 0.0985537102856164 1.0 0.7926277900753033 6 Q03164,Q9H7B4 2
16
+ L27 domain [IPR004172] 0.8561657241539795 1.5920146802615252 0.1113814060487816 1.0 0.7950746618090171 3 Q9NZW5 1
17
+ L27 domain, C-terminal [IPR014775] 0.8561657241539795 1.5920146802615252 0.1113814060487816 1.0 0.7950746618090171 3 Q9NZW5 1
18
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.7665920173373151 1.5839197894319024 0.113211973375277 1.0 0.8005115852845155 4 Q15629,Q96CP7 2
19
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8432388947826948 1.5428742199927263 0.1228612969377547 1.0 0.8322374483977558 3 Q32P28 1
20
+ Peptidase M28 [IPR007484] 0.8409425625920475 1.534134187396084 0.1249966442844687 1.0 0.8322374483977558 3 P02786,Q969V3 2
21
+ Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.8319204249903323 1.4997673660821609 0.1336746734237679 1.0 0.8322374483977558 3 Q06124 1
22
+ Cyclic nucleotide-binding domain [IPR000595] 0.716216621749954 1.498471186681286 0.1340108732574241 1.0 0.8322374483977558 5 Q6P4Q7,P10644 2
23
+ PA domain [IPR003137] 0.9720279720279724 1.4398863172413654 0.1498995648194969 1.0 0.8594402046655165 2 Q8TCT8 1
24
+ Tubulin/FtsZ, GTPase domain [IPR003008] 0.6723184666420852 1.4329925843759317 0.1518599565652023 1.0 0.863102272530425 6 Q9BVA1,P04350,Q9BUF5,Q13885,P07437 5
25
+ Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6723184666420852 1.4329925843759317 0.1518599565652023 1.0 0.863102272530425 6 Q9BVA1,P04350,Q9BUF5,Q13885,P07437 5
26
+ U-box domain [IPR003613] 0.6881423401315505 1.3825640935264765 0.166798565195434 1.0 0.867820549055376 5 O95155,Q7Z6E9 2
27
+ SH2 domain [IPR000980] 0.6667757698122394 1.3737845037361 0.1695085933467512 1.0 0.867820549055376 8 P42224,Q06124 2
28
+ RecF/RecN/SMC, N-terminal [IPR003395] 0.6543757335544549 1.3559930923590624 0.1751013658876683 1.0 0.867820549055376 6 Q8IY18 1
29
+ Tudor domain [IPR002999] 0.6616548316892872 1.3518601778266586 0.1764200487800939 1.0 0.867820549055376 8 Q9Y2W6,Q14739 2
30
+ Sterile alpha motif domain [IPR001660] 0.7082526675904333 1.3518176431950737 0.1764336586197106 1.0 0.867820549055376 4 Q13136 1
31
+ Immunoglobulin-like domain [IPR007110] 0.6585302257046518 1.3384710310403212 0.1807429375669049 1.0 0.8697675627683108 8 P10586,P10321,Q08722 3
32
+ Fxr1, tudor domain [IPR041560] 0.77098674521355 1.2670109383784551 0.2051513787282337 1.0 0.911701023413244 3 P51116,Q06787 2
33
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.77098674521355 1.2670109383784551 0.2051513787282337 1.0 0.911701023413244 3 P51116,Q06787 2
34
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.77098674521355 1.2670109383784551 0.2051513787282337 1.0 0.911701023413244 3 P51116,Q06787 2
35
+ Agenet-like domain [IPR008395] 0.77098674521355 1.2670109383784551 0.2051513787282337 1.0 0.911701023413244 3 P51116,Q06787 2
36
+ EGF-like calcium-binding domain [IPR001881] 0.9227088700772916 1.2547536482244497 0.2095682038309836 1.0 0.918630181722526 2 Q07954 1
37
+ Alpha-L-fucosidase, C-terminal [IPR031919] 0.9175561280824442 1.2354911605251988 0.2166477642377602 1.0 0.9229356793827171 2 Q9BTY2 1
38
+ Reticulon [IPR003388] 0.7583624890758807 1.218799422322485 0.2229203308281668 1.0 0.9229356793827171 3 O95197 1
39
+ Peptidase M16, C-terminal [IPR007863] 0.6250059029601326 1.2118001010747543 0.2255889096261358 1.0 0.9229356793827171 7 Q10713,Q5JRX3 2
40
+ Peptidase M16, N-terminal [IPR011765] 0.6250059029601326 1.2118001010747543 0.2255889096261358 1.0 0.9229356793827171 7 Q10713,Q5JRX3 2
41
+ RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8895841001104168 1.1313795374996345 0.2578953802759116 1.0 0.9646739183250552 2 P98179 1
42
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.6512106368132519 1.1236402899872844 0.2611656565990365 1.0 0.9646739183250552 4 Q9HCE1 1
43
+ NOPS [IPR012975] 0.7319587628865987 1.1182331439680258 0.2634674321728572 1.0 0.9646739183250552 3 Q8WXF1,P23246 2
44
+ Brix domain [IPR007109] 0.7301178203240066 1.1112413552594942 0.2664644747433584 1.0 0.9646739183250552 3 Q9H7B2,Q8TDN6 2
45
+ High mobility group box domain [IPR009071] 0.6176030582199017 1.11116477520987 0.2664974302746259 1.0 0.9646739183250552 11 Q00059,O96028,O75717,O15347,P17480,Q969G3 6
46
+ GOLD domain [IPR009038] 0.6014884111172358 1.1102711473207636 0.2668822022617059 1.0 0.9646739183250552 7 Q9Y3A6,Q9H3P7,O76054,Q9Y3B3,Q15363 5
47
+ Extended PHD (ePHD) domain [IPR034732] 0.8737578211262433 1.072916553468804 0.283308558203033 1.0 0.9655099678082488 2 Q03164 1
48
+ Biotin carboxylase, C-terminal [IPR005482] 0.6097686951383522 1.0569695808219703 0.2905254705497262 1.0 0.9655099678082488 5 Q96RQ3,P05165 2
49
+ Biotin carboxylation domain [IPR011764] 0.6097686951383522 1.0569695808219703 0.2905254705497262 1.0 0.9655099678082488 5 Q96RQ3,P05165 2
50
+ Biotin carboxylase-like, N-terminal domain [IPR005481] 0.6097686951383522 1.0569695808219703 0.2905254705497262 1.0 0.9655099678082488 5 Q96RQ3,P05165 2
51
+ Peptidase S8/S53 domain [IPR000209] 0.8689731321310287 1.0553201949603244 0.2912789079536646 1.0 0.9655099678082488 2 O14773 1
52
+ FAD linked oxidase, N-terminal [IPR006094] 0.8675009201325012 1.0499139787023788 0.2937576640579831 1.0 0.9655099678082488 2 Q15392 1
53
+ FAD-binding domain, PCMH-type [IPR016166] 0.8675009201325012 1.0499139787023788 0.2937576640579831 1.0 0.9655099678082488 2 Q15392 1
54
+ Fibronectin type II domain [IPR000562] 0.849098270150904 0.9826896294343944 0.325760216312805 1.0 0.979155958739114 2 P11717 1
55
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.846889952153112 0.9746706058499908 0.3297236780318366 1.0 0.979155958739114 2 P10321 1
56
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.846889952153112 0.9746706058499908 0.3297236780318366 1.0 0.979155958739114 2 P10321 1
57
+ MHC class I-like antigen recognition-like [IPR011161] 0.846889952153112 0.9746706058499908 0.3297236780318366 1.0 0.979155958739114 2 P10321 1
58
+ Immunoglobulin C1-set [IPR003597] 0.846889952153112 0.9746706058499908 0.3297236780318366 1.0 0.979155958739114 2 P10321 1
59
+ Isopropylmalate dehydrogenase-like domain [IPR024084] 0.6083588257801 0.953349415140089 0.3404130620946741 1.0 0.979155958739114 4 P48735 1
60
+ Legume-like lectin [IPR005052] 0.8395288921604729 0.948022698124684 0.3431178990855206 1.0 0.979155958739114 2 Q12907 1
61
+ 4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.6638958386337924 0.8630508603323658 0.3881095038563122 1.0 0.9940868840161676 3 Q16134 1
62
+ CTP synthase GATase domain [IPR033828] 0.8126610231873412 0.8519787842847345 0.3942258673987528 1.0 0.9960496149624528 2 Q9NRF8 1
63
+ CTP synthase, N-terminal [IPR017456] 0.8126610231873412 0.8519787842847345 0.3942258673987528 1.0 0.9960496149624528 2 Q9NRF8 1
64
+ Zinc finger, RanBP2-type [IPR001876] 0.5434762324148645 0.8444343037214027 0.398426760122835 1.0 0.9960496149624528 8 Q92804 1
65
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.5329224512793989 0.832357709199831 0.4052070655719983 1.0 0.9960496149624528 6 Q06124 1
66
+ Domain of unknown function DUF1605 [IPR011709] 0.5388968807776319 0.776916430944162 0.4372080765347537 1.0 0.9960496149624528 11 Q9H2U1,Q14562,Q92620 3
67
+ Helicase-associated domain [IPR007502] 0.5388968807776319 0.776916430944162 0.4372080765347537 1.0 0.9960496149624528 11 Q9H2U1,Q14562,Q92620 3
68
+ Chromo/chromo shadow domain [IPR000953] 0.522492625368739 0.7719006192447144 0.4401732905445177 1.0 0.9960496149624528 7 Q13185,P45973,P83916,Q14839,Q8TAQ2,O14646 6
69
+ Peptidase C2, calpain, domain III [IPR022683] 0.7828487302171541 0.7481770932633743 0.454353345901934 1.0 0.9960496149624528 2 P07384 1
70
+ Calpain subdomain III [IPR033883] 0.7828487302171541 0.7481770932633743 0.454353345901934 1.0 0.9960496149624528 2 P07384 1
71
+ Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.7828487302171541 0.7481770932633743 0.454353345901934 1.0 0.9960496149624528 2 P07384 1
72
+ Peptidase C2, calpain, catalytic domain [IPR001300] 0.7828487302171541 0.7481770932633743 0.454353345901934 1.0 0.9960496149624528 2 P07384 1
73
+ Exportin-2, central domain [IPR013713] 0.6299705449189996 0.7400285679325721 0.4592826601036064 1.0 0.9960496149624528 3 O15397,O95373 2
74
+ Myosin head, motor domain [IPR001609] 0.5103244837758192 0.720879210289037 0.4709838349407431 1.0 0.9960496149624528 7 Q7Z406,O00159,P35580,Q9UM54,O94832,O43795 6
75
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7707029812292999 0.7069093466085864 0.4796228152389257 1.0 0.9960496149624528 2 P51116 1
76
+ Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.5222204118440826 0.7000798048963538 0.4838774670526788 1.0 0.9960496149624528 5 Q8NC60 1
77
+ ZU5 domain [IPR000906] 0.7684946632315084 0.6994777840778533 0.4842534919983201 1.0 0.9960496149624528 2 Q07157 1
78
+ Protein-tyrosine phosphatase, catalytic [IPR003595] 0.5219735271376517 0.6991037153103625 0.4844872168366534 1.0 0.9960496149624528 5 Q06124 1
79
+ CARG-binding factor, N-terminal [IPR012956] 0.7673905042326125 0.6957706148478896 0.4865724945675147 1.0 0.9960496149624528 2 Q99729 1
80
+ Glycosyltransferase 2-like [IPR001173] 0.6096068738134752 0.668289136522725 0.5039490464388647 1.0 0.9960496149624528 3 Q10472 1
81
+ AMP-binding enzyme, C-terminal domain [IPR025110] 0.6082474226804137 0.6635673303476589 0.5069672726602141 1.0 0.9960496149624528 3 P33121,Q6P1M0 2
82
+ Peptidase S9A, N-terminal domain [IPR023302] 0.7574530732425501 0.6626734911585525 0.5075396910474168 1.0 0.9960496149624528 2 Q4J6C6 1
83
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.6060792012527786 0.6560552105477744 0.5117886013552924 1.0 0.9960496149624528 3 P16615 1
84
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.6060792012527786 0.6560552105477744 0.5117886013552924 1.0 0.9960496149624528 3 P16615 1
85
+ RBM1CTR [IPR012604] 0.7541405962458625 0.6517520515657735 0.5145611379139161 1.0 0.9960496149624528 2 P38159 1
86
+ CCAAT-binding factor [IPR005612] 0.6020392065351343 0.6421211541819891 0.5207945216662739 1.0 0.9960496149624528 3 Q9BVI4 1
87
+ APC10/DOC domain [IPR004939] 0.7478836952521197 0.6312815026138574 0.5278564792966742 1.0 0.9960496149624528 2 Q5T447 1
88
+ Post-SET domain [IPR003616] 0.5148683387228262 0.5972103242908001 0.5503669670653601 1.0 0.9960496149624528 4 Q03164 1
89
+ Immunoglobulin subtype 2 [IPR003598] 0.5123942228523072 0.5883023428895485 0.5563293732910903 1.0 0.9960496149624528 4 P10586,Q13308 2
90
+ N-acetylgalactosaminyltransferase [IPR045885] 0.7338976812661058 0.5863188096418901 0.5576612931527907 1.0 0.9960496149624528 2 Q10472 1
91
+ Myosin, N-terminal, SH3-like [IPR004009] 0.5097605893186088 0.5788608574232603 0.5626830635201485 1.0 0.9960496149624528 4 P35580,Q7Z406,Q9UM54 3
92
+ BTB/POZ domain [IPR000210] 0.5062165914651898 0.566224093976995 0.5712414530295515 1.0 0.9960496149624528 4 Q08380 1
93
+ LEM domain [IPR003887] 0.4678696008032633 0.5624179415566858 0.5738312978159024 1.0 0.9960496149624528 6 Q86XL3 1
94
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.4855961537854876 0.5585073703521756 0.5764979730542741 1.0 0.9960496149624528 5 P08183 1
95
+ PTB/PI domain [IPR006020] 0.7243283032756754 0.5562330907884372 0.5780515205749344 1.0 0.9960496149624528 2 Q9UKG1 1
96
+ Glutamine amidotransferase [IPR017926] 0.5032383400859347 0.5556670369481181 0.5784384946105285 1.0 0.9960496149624528 4 Q9NRF8 1
97
+ Sorting nexin, N-terminal [IPR005329] 0.7213838792786199 0.547093512221472 0.5843144892549259 1.0 0.9960496149624528 2 Q13596 1
98
+ Class II aldolase/adducin N-terminal [IPR001303] 0.7202797202797242 0.543680857047236 0.5866611077359449 1.0 0.9960496149624528 2 Q9UEY8 1
99
+ Immunoglobulin I-set [IPR013098] 0.569732221823172 0.5340050798416254 0.5933380195262823 1.0 0.9960496149624528 3 P10586 1
100
+ Radical SAM [IPR007197] 0.7140228192859812 0.5244971210173234 0.5999328217105777 1.0 0.9960496149624528 2 Q5VV42 1
101
+ Elp3/MiaB/NifB [IPR006638] 0.7140228192859812 0.5244971210173234 0.5999328217105777 1.0 0.9960496149624528 2 Q5VV42 1
102
+ Thioredoxin-like fold [IPR012336] 0.7110783952889256 0.5155624106653262 0.606160069531031 1.0 0.9960496149624528 2 Q6DKJ4 1
103
+ Ricin B, lectin domain [IPR000772] 0.5582982984209484 0.4973494800160491 0.6189426248541159 1.0 0.9960496149624528 3 Q10472 1
104
+ AMP-dependent synthetase/ligase [IPR000873] 0.4635224760501161 0.4771084950637315 0.6332848657647121 1.0 0.9960496149624528 5 O95573,Q4G176,Q6P1M0,P33121 4
105
+ Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4754524773849041 0.4602287652992998 0.6453520258518597 1.0 0.9960496149624528 4 Q13596 1
106
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.6886271623113773 0.4495185726105727 0.6530576132759347 1.0 0.9960496149624528 2 P34897 1
107
+ PDZ domain [IPR001478] 0.4886002183164641 0.434369407271607 0.6640202096054295 1.0 0.9960496149624528 21 Q6ZWJ1,Q8TEU7,O43464,Q14168,Q9NZW5,Q9HD26,Q00013 7
108
+ ELMO domain [IPR006816] 0.6820022083180023 0.4307777088787007 0.6666300092384336 1.0 0.9960496149624528 2 Q96JJ3 1
109
+ SNF2, N-terminal [IPR000330] 0.4476668031712637 0.4279493535565365 0.6686879940125343 1.0 0.9960496149624528 10 P46100 1
110
+ SAC3/GANP/THP3, conserved domain [IPR005062] 0.6808980493191066 0.4276891604331302 0.6688774426839033 1.0 0.9960496149624528 2 A6NKF1 1
111
+ PITH domain [IPR010400] 0.6797938903202108 0.4246107417162891 0.6711204611658279 1.0 0.9960496149624528 2 O43396 1
112
+ Chromo domain subgroup [IPR017984] 0.5287187039764375 0.4071984967168554 0.6838622056184644 1.0 0.9960496149624528 3 Q13185,P83916 2
113
+ Chromo shadow domain [IPR008251] 0.5287187039764375 0.4071984967168554 0.6838622056184644 1.0 0.9960496149624528 3 Q13185,P83916 2
114
+ Ribosomal L28e/Mak16 [IPR029004] 0.6621273463378774 0.3767789019352675 0.7063379210363017 1.0 0.9960496149624528 2 P46779 1
115
+ S1 domain [IPR003029] 0.4131957242904508 0.3549003663086748 0.7226642340427181 1.0 0.9960496149624528 6 Q7KZ85,P62487,Q14690,Q8TCS8,Q14562 5
116
+ RNA-binding domain, S1 [IPR022967] 0.4131957242904508 0.3549003663086748 0.7226642340427181 1.0 0.9960496149624528 6 Q7KZ85,P62487,Q14690,Q8TCS8,Q14562 5
117
+ Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.653662127346343 0.3548490457258205 0.722702683036101 1.0 0.9960496149624528 2 P16435 1
118
+ FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.653662127346343 0.3548490457258205 0.722702683036101 1.0 0.9960496149624528 2 P16435 1
119
+ Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.653662127346343 0.3548490457258205 0.722702683036101 1.0 0.9960496149624528 2 P16435 1
120
+ Myosin tail [IPR002928] 0.5095729013254804 0.3529477022026947 0.7241276480186392 1.0 0.9960496149624528 3 Q7Z406,P35580 2
121
+ WW domain [IPR001202] 0.4125772871166175 0.3036071521901568 0.7614272019931061 1.0 0.9960496149624528 10 Q6ZWJ1,Q8N1G2,P46939 3
122
+ Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479] 0.3975941492753713 0.30086202774586 0.7635197069603166 1.0 0.9960496149624528 6 Q96RQ3,P05165 2
123
+ PTBP1, RNA recognition motif 2-like [IPR021790] 0.4220994475138202 0.2964834237640115 0.7668609241518387 1.0 0.9960496149624528 4 P14866,Q8WVV9,P26599 3
124
+ Syntaxin, N-terminal domain [IPR006011] 0.4768041237113418 0.2687834256228872 0.7880963485816848 1.0 0.9960496149624528 3 Q12846,O15400 2
125
+ OCRE domain [IPR041591] 0.6124401913875657 0.2580686984339576 0.7963538885507568 1.0 0.9960496149624528 2 P52756 1
126
+ Ubiquitin-associated domain [IPR015940] 0.3967236832112617 0.2518882047407608 0.8011274769534302 1.0 0.9960496149624528 10 Q9UPU5 1
127
+ Ribosomal protein L30, N-terminal [IPR012988] 0.6083916083916143 0.2495112705429417 0.8029653239071657 1.0 0.9960496149624528 2 P18124 1
128
+ Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.6083916083916143 0.2495112705429417 0.8029653239071657 1.0 0.9960496149624528 2 P18124 1
129
+ Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.6083916083916143 0.2495112705429417 0.8029653239071657 1.0 0.9960496149624528 2 P18124 1
130
+ PWWP domain [IPR000313] 0.3776516174519193 0.2146278612241975 0.8300574699920131 1.0 0.9960496149624528 8 Q7Z4V5 1
131
+ Ribosome receptor lysine/proline rich [IPR007794] 0.5877806404122257 0.2087120935267089 0.8346729987820081 1.0 0.9960496149624528 2 Q9P2E9 1
132
+ TOG domain [IPR034085] 0.3709708712698893 0.2051168626240937 0.8374808220604553 1.0 0.9960496149624528 7 Q86Y56,O00410 2
133
+ Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364] 0.3782688766114301 0.187023858057591 0.8516419269528797 1.0 0.9960496149624528 4 P14868,O43776,Q15046 3
134
+ Cold-shock (CSD) domain [IPR019844] 0.371867113144368 0.1732445123010214 0.8624592368269755 1.0 0.9960496149624528 4 P16989 1
135
+ KOW [IPR005824] 0.3651436993367785 0.1729566747205847 0.8626854828716906 1.0 0.9960496149624528 5 O00267,P61254,P62701,P61353 4
136
+ MIRO domain [IPR020860] 0.5660655134339412 0.1708285551502258 0.8643585753337064 1.0 0.9960496149624528 2 Q8IXI1 1
137
+ EF hand associated, type-1 [IPR013566] 0.5660655134339412 0.1708285551502258 0.8643585753337064 1.0 0.9960496149624528 2 Q8IXI1 1
138
+ EF hand associated, type-2 [IPR013567] 0.5660655134339412 0.1708285551502258 0.8643585753337064 1.0 0.9960496149624528 2 Q8IXI1 1
139
+ GUCT [IPR012562] 0.5623849834376217 0.1649313105414195 0.868998047625609 1.0 0.9960496149624528 2 Q9BQ39 1
140
+ DDT domain [IPR018501] 0.56017666543983 0.1614657966820939 0.8717265481447796 1.0 0.9960496149624528 2 Q9NRL2 1
141
+ WSTF/Acf1/Cbp146 [IPR013136] 0.56017666543983 0.1614657966820939 0.8717265481447796 1.0 0.9960496149624528 2 Q9NRL2 1
142
+ WHIM2 domain [IPR028941] 0.56017666543983 0.1614657966820939 0.8717265481447796 1.0 0.9960496149624528 2 Q9NRL2 1
143
+ Importin-beta, N-terminal domain [IPR001494] 0.3731184594673272 0.152453939309486 0.8788289168069872 1.0 0.9960496149624528 13 Q8TEX9,O15397,O95373,Q9HAV4,O00410,Q92973 6
144
+ Peptidase M20, dimerisation domain [IPR011650] 0.5454545454545524 0.1397521056071765 0.8888558560077968 1.0 0.9960496149624528 2 Q96KP4 1
145
+ Saccharopine dehydrogenase-like, C-terminal [IPR032095] 0.5406698564593373 0.1332116887829386 0.8940259669238917 1.0 0.9960496149624528 2 Q8NBX0 1
146
+ Saccharopine dehydrogenase, NADP binding domain [IPR005097] 0.5406698564593373 0.1332116887829386 0.8940259669238917 1.0 0.9960496149624528 2 Q8NBX0 1
147
+ Spt5 C-terminal domain [IPR024945] 0.5391976444608095 0.131249740394306 0.8955777491041559 1.0 0.9960496149624528 2 O00267 1
148
+ mRNA splicing factor Cwf21 domain [IPR013170] 0.539197644460809 0.1312497403943054 0.8955777491041563 1.0 0.9960496149624528 2 O15042 1
149
+ RNA-binding S4 domain [IPR002942] 0.402061855670105 0.1246446511608087 0.9008048775070154 1.0 0.9960496149624528 3 Q9NV31,P62701 2
150
+ Macro domain [IPR002589] 0.4009572901325496 0.123045969321812 0.9020706962634896 1.0 0.9960496149624528 3 Q9P0M6,O75367 2
151
+ Hexokinase, C-terminal [IPR022673] 0.5322046374678027 0.1222523501194509 0.9026991679423388 1.0 0.9960496149624528 2 P52789 1
152
+ Hexokinase, N-terminal [IPR022672] 0.5322046374678027 0.1222523501194509 0.9026991679423388 1.0 0.9960496149624528 2 P52789 1
153
+ Cold shock domain [IPR011129] 0.3424056373315506 0.1211319925998115 0.9035864893150076 1.0 0.9960496149624528 5 P16989 1
154
+ Cold-shock protein, DNA-binding [IPR002059] 0.3424056373315506 0.1211319925998115 0.9035864893150076 1.0 0.9960496149624528 5 P16989 1
155
+ Mu homology domain [IPR028565] 0.3436464088397842 0.1196558235902611 0.9047557965142904 1.0 0.9960496149624528 4 Q9Y2T2,P48444,Q96CW1 3
156
+ Suppressor of forked [IPR008847] 0.5230033124770042 0.111213570459008 0.9114469907200312 1.0 0.9960496149624528 2 Q12996 1
157
+ SMARCC, SWIRM-associated domain [IPR032448] 0.5215311004784764 0.109530491275778 0.9127817387081985 1.0 0.9960496149624528 2 Q8TAQ2 1
158
+ SMARCC, N-terminal [IPR032450] 0.5215311004784764 0.109530491275778 0.9127817387081985 1.0 0.9960496149624528 2 Q8TAQ2 1
159
+ SMARCC, C-terminal [IPR032451] 0.5215311004784764 0.109530491275778 0.9127817387081985 1.0 0.9960496149624528 2 Q8TAQ2 1
160
+ Gamma tubulin complex component protein, N-terminal [IPR041470] 0.5193227824806846 0.1070483515111283 0.914750621144894 1.0 0.9960496149624528 2 Q96CW5 1
161
+ Gamma tubulin complex component, C-terminal [IPR040457] 0.5193227824806846 0.1070483515111283 0.914750621144894 1.0 0.9960496149624528 2 Q96CW5 1
162
+ RNA polymerase Rpb2, domain 3 [IPR007645] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 0.9960496149624528 2 P30876 1
163
+ RNA polymerase Rpb2, domain 2 [IPR007642] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 0.9960496149624528 2 P30876 1
164
+ RNA polymerase, beta subunit, protrusion [IPR007644] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 0.9960496149624528 2 P30876 1
165
+ DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 0.9960496149624528 2 P30876 1
166
+ RNA polymerase Rpb2, domain 7 [IPR007641] 0.5178505704821569 0.1054217629049062 0.9160411479831324 1.0 0.9960496149624528 2 P30876 1
167
+ Exportin-1/Importin-beta-like [IPR013598] 0.3325966850828764 0.1018896126778137 0.9188442949345524 1.0 0.9960496149624528 4 Q9HAV4,O14980,Q9Y5L0 3
168
+ LEM-like domain [IPR013146] 0.5145380934854694 0.1018437280071139 0.918880716145658 1.0 0.9960496149624528 2 P42166 1
169
+ G-patch domain [IPR000467] 0.3487146275389919 0.092010630756157 0.9266895933012904 1.0 0.9960496149624528 13 Q8IWZ8,Q8N1G2,Q5T3I0 3
170
+ Plectin/S10, N-terminal [IPR005326] 0.5012881854987197 0.0886402821851396 0.9293677935137892 1.0 0.9960496149624528 2 P46783 1
171
+ Ataxin-2, C-terminal [IPR009818] 0.372238586156114 0.0868244491401079 0.9308110534036556 1.0 0.9960496149624528 3 Q9H074,Q14694 2
172
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.3355269612318142 0.0856676740216639 0.9317306000222204 1.0 0.9960496149624528 10 P62942,O95302 2
173
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.4976076555024002 0.0852792564549877 0.9320393823995196 1.0 0.9960496149624528 2 Q92945 1
174
+ CAP Gly-rich domain [IPR000938] 0.3197053406998202 0.0834330102871079 0.9335072415909664 1.0 0.9960496149624528 4 Q15813,Q14203,Q99426 3
175
+ EF-hand, Ca insensitive [IPR014837] 0.3630338733431538 0.0773202446230413 0.9383687862362426 1.0 0.9960496149624528 3 O43707,Q13813 2
176
+ B-box-type zinc finger [IPR000315] 0.3145003251578375 0.0766624714023017 0.9388920601263382 1.0 0.9960496149624528 4 P19474 1
177
+ Aldehyde dehydrogenase domain [IPR015590] 0.3271078688646994 0.0748539512614495 0.9403309152835704 1.0 0.9960496149624528 9 P30837 1
178
+ Lsm14-like, N-terminal [IPR025609] 0.479941111520067 0.070906312325725 0.9434723195139412 1.0 0.9960496149624528 2 Q96F86 1
179
+ DFDF domain [IPR025762] 0.479941111520067 0.070906312325725 0.9434723195139412 1.0 0.9960496149624528 2 Q96F86 1
180
+ FDF domain [IPR019050] 0.479941111520067 0.070906312325725 0.9434723195139412 1.0 0.9960496149624528 2 Q96F86 1
181
+ EF-hand domain [IPR002048] 0.4252304300460687 0.0657446454392694 0.9475811273582792 1.0 0.9960496149624528 39 P80303,Q14257,Q15293 3
182
+ Ribosomal protein S7 domain [IPR023798] 0.47147589252853 0.0649979057950727 0.9481756676640228 1.0 0.9960496149624528 2 P46782 1
183
+ Forkhead-associated (FHA) domain [IPR000253] 0.3202125101566966 0.0605100907556084 0.9517493793171758 1.0 0.9960496149624528 9 Q15058 1
184
+ Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.4608023555392061 0.058385871526113 0.9534412684627248 1.0 0.9960496149624528 2 P47897 1
185
+ Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.4600662495399399 0.0579627630801618 0.953778289392277 1.0 0.9960496149624528 2 Q13243 1
186
+ B-box, C-terminal [IPR003649] 0.4585940375414146 0.0571288819739562 0.9544425294994648 1.0 0.9960496149624528 2 O15164 1
187
+ SUN domain [IPR012919] 0.4457121825542942 0.0505069882267557 0.9597183807143248 1.0 0.9960496149624528 2 Q9UH99 1
188
+ AP complex, mu/sigma subunit [IPR022775] 0.3026235956042772 0.0504393690458427 0.95977226433566 1.0 0.9960496149624528 5 P53680 1
189
+ FCP1 homology domain [IPR004274] 0.4446080235553984 0.0499933996111214 0.9601276480936816 1.0 0.9960496149624528 2 Q3ZCQ8 1
190
+ Core histone macro-H2A, macro domain [IPR035796] 0.4412955465587109 0.0485012975262465 0.9613167303840976 1.0 0.9960496149624528 2 Q9P0M6 1
191
+ ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284] 0.4357747515642338 0.0461718645598886 0.9631732673790576 1.0 0.9960496149624528 2 O94762 1
192
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.3115472289313566 0.0436623355908581 0.96517356241236 1.0 0.9960496149624528 9 P08183 1
193
+ UAS [IPR006577] 0.4221567905778502 0.0412091098745394 0.9671291912137084 1.0 0.9969426765044604 2 Q96CS3 1
194
+ NUC153 [IPR012580] 0.4188443135811648 0.0401580457804312 0.9679671252465244 1.0 0.9969426765044604 2 Q9BSC4 1
195
+ ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.4059624585940462 0.0365908085196106 0.9708112723628372 1.0 0.9969426765044604 2 Q14240 1
196
+ Phox homology [IPR001683] 0.3076585043477867 0.0365294169788973 0.9708602229996596 1.0 0.9969426765044604 9 Q9UMY4,Q13596 2
197
+ Ribosomal protein S4/S9, N-terminal [IPR001912] 0.4019138755980944 0.035627465512669 0.9715794079075186 1.0 0.9969426765044604 2 Q9NV31 1
198
+ SPRY-associated [IPR006574] 0.2805596465390302 0.0293050454510683 0.9766213029439264 1.0 0.9969426765044604 3 Q14258,P19474 2
199
+ PSI domain [IPR016201] 0.3592197276407883 0.0290183933270795 0.9768499210174496 1.0 0.9969426765044604 2 O15031 1
200
+ SH3 domain [IPR001452] 0.3645624438246375 0.0199759019561402 0.9840625961828612 1.0 1.0 28 P46108,Q9UQB8,Q14168,Q96PC5,Q9NZW5,Q00013 6
201
+ K Homology domain, type 1 [IPR004088] 0.3416595153838448 0.0106319108894912 0.9915171222636674 1.0 1.0 23 Q07666,Q15637,Q8IWZ3,P51116,Q9Y2W6,O75179,Q06787 7
202
+ C2 domain [IPR000008] 0.2886199216870004 0.0054137759014717 0.9956804528928253 1.0 1.0 9 Q99829,A0FGR8 2
interpro_domain/selections.json ADDED
The diff for this file is too large to render. See raw diff
 
interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Tubulin [IPR000217]", "1": "Beta tubulin [IPR002453]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 8de4bc830bdeba56a05345efb760073292b18557450666a5f91bc346f70130ae
  • Pointer size: 131 Bytes
  • Size of remote file: 124 kB
interpro_family/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: f1db2341254a302028f67090b1a7f988fe8aeaaf2e7333f6e03ad41165c34508
  • Pointer size: 131 Bytes
  • Size of remote file: 127 kB