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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:3e1f5243d7494cb91bfecdf2b0f2548ff137c588f73fab6ae50ef0ae9aae9455
+size 70990

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3137,
+    "annotations_size": 58,
+    "title": "Average number of proteins per term",
+    "value": 2.689655172413793
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C279/C279_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,8 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cysteine peptidase, cysteine active site [IPR000169]	0.6346205028808265	1.2260216065834235	0.2201905442625578	0.9999994563331828	0.8254516455950358	5	P07384	1
+Peptidase S9, serine active site [IPR002471]	0.6609250398724199	0.3803807858058152	0.7036627753497242	1.0	0.927708592053748	2	P13798	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.2140041739665796	0.325751148923496	0.7446126418344536	1.0	0.9597229605866292	45	P48729,O15111,Q8TD19,P17612,P36507,P27361,P06493,O14757,P31749,O43293,Q13464,P10398,P49840	13
+Thiolase, active site [IPR020610]	0.3722587053031565	0.2493998063163547	0.8030515349533698	1.0	0.9909997665382012	5	P42765	1
+Thiolase, acyl-enzyme intermediate active site [IPR020615]	0.3575989782886254	0.216481144890485	0.8286127209119523	1.0	1.0	5	P55084,P42765,P09110,P22307	4
+L-lactate dehydrogenase, active site [IPR018177]	0.5212121212121301	0.1059917647107627	0.9155888861888732	1.0	1.0	2	P00338	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.2984360038301969	0.0754221775929394	0.9398788142954596	1.0	1.0	4	P38606,P21281,P25705	3

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CASP7", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "DAPK3", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME6", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TP53RK", "TPI1", "TPP2", "TTK", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACAA1", "ACAA2", "AKT1", "APEH", "ARAF", "ATP5A1", "ATP6V1A", "ATP6V1B2", "CAPN1", "CDK1", "CHEK1", "CHUK", "CSNK1A1", "DAPK3", "GSK3A", "HADHB", "LDHA", "MAP2K2", "MAPK3", "NEK9", "PRKACA", "ROCK1", "SCP2"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "IQ motif, EF-hand binding site [IPR000048]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "IQ motif, EF-hand binding site [IPR000048]", "1": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:bfe6f03030f1fbcd1aa694af18f51071b4d39b5fa1966b500a766d80e3688e9a
+size 70923

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+IQ motif, EF-hand binding site [IPR000048]	5	11	2.077002479510992	0.0378013303726314	4.902912621359223	10.79368932038835	-0.2273048691062784	0.5134620963427197	2.787853554074696	2.339749173467172	1.002129759133213	0.3214407723554939	1.0	0.1788224008957527	0.3263246311566628	0.0734338910721259	0.0122973883017787
+Beta tubulin, autoregulation binding site [IPR013838]	4	5	2.0570669701068	0.0396797843671568	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0	1.0	1.0	0.0190953097419897	0.0005820850870238

interpro_binding_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3137,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.612903225806452
+}

interpro_binding_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C279/C279_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+IQ motif, EF-hand binding site [IPR000048]	0.6501401037717061	2.0770024795109916	0.0378013303726314	0.6971641298698665	0.3075183288454652	11	P35580,Q13576,O94832,P35579,Q7Z406	5
+Beta tubulin, autoregulation binding site [IPR013838]	0.8282247765006296	2.0570669701067996	0.0396797843671568	0.7149649881924908	0.3075183288454652	5	P04350,P07437,Q13885,Q9BUF5	4
+Biotin-binding site [IPR001882]	0.774337695499522	1.5843473205045755	0.113114702844927	0.9757957789250618	0.5714808180682475	4	P05165,Q96RQ3,P11498	3
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.9023923444976084	1.2285077695041544	0.2192564145793845	0.9995346698768216	0.7596335134554203	2	P34897	1
+Protein kinase, ATP binding site [IPR017441]	0.2095644838505554	0.3190714871651314	0.7496723044475218	1.0	1.0	44	P48729,O15111,P17612,P36507,P27361,P06493,O14757,P31749,O43293,Q13464,P41240,P10398,P49840	13

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARAF", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DAPK3", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP2K2", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT1", "ARAF", "CDK1", "CHEK1", "CHUK", "CSK", "CSNK1A1", "DAPK3", "GSK3A", "IQGAP2", "MAP2K2", "MAPK3", "MCCC1", "MYH10", "MYH14", "MYH9", "MYO1D", "PC", "PCCA", "PRKACA", "ROCK1", "SHMT2", "TUBB", "TUBB2A", "TUBB4A", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Kinesin motor domain, conserved site [IPR019821]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Kinesin motor domain, conserved site [IPR019821]", "1": "Actinin-type actin-binding domain, conserved site [IPR001589]", "2": "Zinc finger, PHD-type, conserved site [IPR019786]", "3": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "4": "Bromodomain, conserved site [IPR018359]", "5": "Zinc finger, RING-type, conserved site [IPR017907]", "6": "WD40 repeat, conserved site [IPR019775]", "7": "Ubiquitin specific protease, conserved site [IPR018200]", "8": "Thiolase, conserved site [IPR020613]", "9": "FERM conserved site [IPR019747]", "10": "Tr-type G domain, conserved site [IPR031157]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:42acb68565ec17ca8dbad5fd53fc115cd95351af2c1d1beadb58475315da71c2
+size 78187

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	3	8	2.4428342950047024	0.014572426490647	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	0.0010343090391069	1.7486004913858212e-06	6.494328716879693e-05	5.5966724052351854e-05
+Guanylate kinase, conserved site [IPR020590]	1	6	2.4400553818681203	0.0146850104181921	2.3980582524271843	5.25	0.6064346340666176	0.4240795168052628	1.6195996498310523	1.4740884957165508	0.9685287933135084	0.3034897017004088	1.0	0.0526645480715484	0.0049445172385496	0.0282524409787331	0.0978216105640502
+Kinesin motor domain, conserved site [IPR019821]	7	16	2.2674919147963317	0.023360192258047	5.145631067961165	12.5752427184466	-0.317280064481527	0.6025720959635847	3.128813066275289	2.1523680093989204	0.789771860748748	0.3101534377819879	1.0	0.1541506060207377	0.2851312580635185	0.2012424218570439	0.0010817402901174

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3137,
+    "annotations_size": 284,
+    "title": "Average number of proteins per term",
+    "value": 2.6901408450704225
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C279/C279_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,49 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7881044584242505	2.4428342950047024	0.014572426490647	0.9845325862919064	0.5650354579322119	8	Q99436,P28072,P28074	3
+Guanylate kinase, conserved site [IPR020590]	0.8673537424935094	2.4400553818681203	0.0146850104181921	0.9850264254049372	0.5650354579322119	6	Q14168	1
+Kinesin motor domain, conserved site [IPR019821]	0.6116823215571499	2.2674919147963313	0.023360192258047	0.9987850011161996	0.5650354579322119	16	P52732,O60282,Q9Y496,O00139,Q14807,O60333,P33176	7
+Tubulin, conserved site [IPR017975]	0.7569573655556265	1.9557712132042424	0.0504921114258754	0.9999995929985704	0.5650354579322119	6	P04350,P07437,Q13885,Q9BUF5	4
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.851320545556009	1.8960234815028527	0.0579569395954084	0.999999956739222	0.5650354579322119	4	P48735	1
+Actinin-type actin-binding domain, conserved site [IPR001589]	0.540280820998953	1.7316764840520014	0.0833311798755862	0.9999999999814504	0.5893324786261962	14	O15020,P21333,Q01082,Q15149,O75369,P12814,O43707,P46939	8
+Zinc finger, PHD-type, conserved site [IPR019786]	0.5205334937308308	1.7059761572258263	0.0880125188720111	0.9999999999956664	0.5951322704678846	16	Q14839,Q9UIG0,O75151,O94880,O95696,Q9BTC0,Q9NRL2,O96028,Q92576,O15164,Q9ULU4,Q12830,Q13263	13
+Ras GTPase-activating protein, conserved site [IPR023152]	0.8640714741544305	1.580358155204674	0.1140248686997686	0.9999999999999988	0.6364276810644388	3	Q13576,P21359	2
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.9881977671451352	1.566441925088844	0.1172451944015828	0.9999999999999996	0.6364276810644388	2	Q16836	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.5918517438788857	1.4699012090024512	0.1415885120970021	1.0	0.6806963399000996	8	O94788	1
+ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]	0.4518923709573672	1.461752350321383	0.1438090858943872	1.0	0.6806963399000996	20	Q7L014,P60842,O00571,P26196,Q86XP3,P41208,P38919,Q92841,Q9H0S4,Q8TDD1,Q9NVP1,Q8N8A6,P17844,Q9GZR7	14
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.5696433966388159	1.356558847599748	0.1749214250795714	1.0	0.7642720726553582	8	O94788	1
+Ubiquitin interacting motif [IPR003903]	0.6555917774572033	1.317104196716262	0.1878037004974699	1.0	0.772593982106936	5	Q92783,Q9Y6I3	2
+Histidine triad, conserved site [IPR019808]	0.9030303030302946	1.2310040350789824	0.21832135512508	1.0	0.8274447962121173	2	Q9BX68	1
+Annexin repeat, conserved site [IPR018252]	0.5901604559334805	1.1918224602859162	0.2333308670033824	1.0	0.8274447962121173	6	P09525,P04083	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.7434970021604432	1.109401846894637	0.2672568659939911	1.0	0.8724247119803848	3	Q9UQ16	1
+Intermediate filament protein, conserved site [IPR018039]	0.515146300468258	1.0799720558216674	0.2801546241034636	1.0	0.8939765533189175	8	Q16352,P07197,P08670,P07196	4
+Bromodomain, conserved site [IPR018359]	0.4405848014975196	0.8460146806034228	0.3975445546184293	1.0	1.0	10	P51532,Q9UIG0,Q8WWQ0,O95696,O15164,Q12830	6
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.5894193284105254	0.8319166785314387	0.4054559769461545	1.0	1.0	4	P56545,Q13363	2
+ABC transporter-like, conserved site [IPR017871]	0.4506479063394879	0.8280080200731044	0.4076659579246733	1.0	1.0	9	P61221,O15439	2
+AT hook, DNA-binding motif [IPR017956]	0.7936204146730466	0.8140592613575505	0.4156110024883253	1.0	1.0	2	Q6ZRS2	1
+GTP1/OBG, conserved site [IPR006074]	0.7811802232854885	0.7689120683687624	0.4419455125717095	1.0	1.0	2	Q9Y295	1
+Cadherin conserved site [IPR020894]	0.6380787297322404	0.7132407330731418	0.475696804696825	1.0	1.0	3	Q14574	1
+Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]	0.7629984051036748	0.7041913970599605	0.4813135878364842	1.0	1.0	2	P23229	1
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.4571507939913114	0.694470535458455	0.4873871725440457	1.0	1.0	7	P49748	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.6314613911933543	0.689663113672724	0.4904060674218153	1.0	1.0	3	O94813,P98164	2
+Sterol reductase, conserved site [IPR018083]	0.7496012759170658	0.6575870694884007	0.5108035055925282	1.0	1.0	2	Q14739	1
+DNA topoisomerase, type IIA, conserved site [IPR018522]	0.7205741626794362	0.5603017238685821	0.5752736517775945	1.0	1.0	2	Q02880	1
+Sugar transporter, conserved site [IPR005829]	0.7129186602870854	0.5355914870993613	0.5922409134825313	1.0	1.0	2	Q7L0J3	1
+HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]	0.7106858054226526	0.5284654774105559	0.5971763020372438	1.0	1.0	2	P17096	1
+Profilin conserved site [IPR027310]	0.6982456140350887	0.4894663647639041	0.6245115616863148	1.0	1.0	2	P07737	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.3184946381771703	0.4604908433808807	0.6451639424387776	1.0	1.0	13	P19474,Q5VTR2,P38398,Q96T88,O15164	5
+WD40 repeat, conserved site [IPR019775]	0.2396937223972733	0.3702256882891477	0.7112143378355567	1.0	1.0	49	Q9GZS3,Q8NI36,P43034,O43815,Q8WUA4,Q9BV38,Q9UNX4,Q9NV06,Q9UMS4,Q8WWQ0,Q9NWT1,Q9UFC0,Q9NVX2,Q12788,P61964	15
+Ubiquitin specific protease, conserved site [IPR018200]	0.2939275355541579	0.3689887905665918	0.7121360799883745	1.0	1.0	13	O94966,P54578,Q93009,Q86UV5,Q96K76	5
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.6363636363636427	0.3159237821254837	0.7520603601723199	1.0	1.0	2	Q9BTY2	1
+Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]	0.6312599681020791	0.3033319888943784	0.7616368702345016	1.0	1.0	2	P98164	1
+Thiolase, conserved site [IPR020613]	0.357713190673918	0.2729218097160358	0.784913321005507	1.0	1.0	6	Q9BWD1,P55084,P42765,P09110,P22307	5
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.5843700159489733	0.2015731665454871	0.8402504245954621	1.0	1.0	2	Q06481	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.5843700159489733	0.2015731665454871	0.8402504245954621	1.0	1.0	2	Q06481	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.5843700159489733	0.2015731665454871	0.8402504245954621	1.0	1.0	2	Q06481	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.5805422647527967	0.1944166545621473	0.8458496502591277	1.0	1.0	2	P30876	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.5767145135566266	0.1874375023788769	0.851317620972541	1.0	1.0	2	P01889	1
+Calreticulin/calnexin, conserved site [IPR018124]	0.4343239221526505	0.153358575619599	0.8781155102615161	1.0	1.0	3	P27797	1
+Ribosomal protein L30, conserved site [IPR018038]	0.5537480063795986	0.1492899027905047	0.881324882394374	1.0	1.0	2	Q6DKI1	1
+FERM conserved site [IPR019747]	0.2390597292923875	0.1252105156414142	0.9003568924846439	1.0	1.0	8	P35241,P15311,Q9Y4F1,P26038,Q9Y490,O43491	6
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.5266347687400428	0.1123590508883949	0.9105387223281388	1.0	1.0	2	P52907	1
+Tr-type G domain, conserved site [IPR031157]	0.2638134781220177	0.1106870273182245	0.911864533463477	1.0	1.0	6	Q05639,P15170,P49411,P13639,Q8N442	5
+Fumarate lyase, conserved site [IPR020557]	0.4606060606060808	0.0553956241455127	0.9558232819125698	1.0	1.0	2	P30566	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BTRC", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ITGA6", "ITGAV", "IVD", "KDM5A", "KDSR", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PATZ1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RING1", "RIOK2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTCA", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCC4", "ABCE1", "ACAA1", "ACAA2", "ACADVL", "ACAT2", "ACTN1", "ACTN4", "ADSL", "ALDH1A2", "ANXA1", "ANXA4", "APLP2", "BAZ1A", "BAZ1B", "BPTF", "BRCA1", "BRD1", "CALR", "CAPZA1", "CETN2", "CHD4", "CTBP1", "CTBP2", "DCAF13", "DDX17", "DDX18", "DDX24", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX6", "DIDO1", "DNM3", "DRG1", "DSC3", "EEF1A2", "EEF2", "EIF4A1", "EIF4A3", "EPB41L2", "EPN1", "EZR", "FARP1", "FLNA", "FLNB", "FUCA2", "GSPT1", "GTF3C2", "GUF1", "HADH", "HADHB", "HINT2", "HLA-B", "HMGA1", "IDH2", "INA", "IQGAP2", "ITGA6", "KIF11", "KIF1B", "KIF22", "KIF2A", "KIF3A", "KIF5B", "KIF5C", "LBR", "LRP2", "LRWD1", "MPP2", "MSN", "NEFL", "NEFM", "NF1", "NLE1", "NSD2", "PAFAH1B1", "PAK1IP1", "PFN1", "PHF14", "PHF2", "PHF3", "PHIP", "PLEC", "POLR2B", "PRPF19", "PSMB5", "PSMB6", "PSMB7", "RDX", "RNF20", "RPL7L1", "SCP2", "SLIT2", "SMARCA4", "SPTBN1", "SPTBN2", "SRCAP", "STAM", "STRN", "SV2A", "TBL3", "TLN1", "TOP2B", "TRIM21", "TRIM24", "TRIM28", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUFM", "UHRF1", "USP14", "USP19", "USP47", "USP48", "USP7", "UTRN", "VIM", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "ZMYND8"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Pleckstrin homology domain [IPR001849]", "2": "WW domain [IPR001202]", "3": "Kinesin motor domain [IPR001752]", "4": "Calponin homology domain [IPR001715]", "5": "LIS1 homology motif [IPR006594]", "6": "RNA recognition motif domain, eukaryote [IPR003954]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Pleckstrin homology domain [IPR001849]", "2": "WW domain [IPR001202]", "3": "Kinesin motor domain [IPR001752]", "4": "Calponin homology domain [IPR001715]", "5": "LIS1 homology motif [IPR006594]", "6": "RNA recognition motif domain, eukaryote [IPR003954]", "7": "K Homology domain [IPR004087]", "8": "SH3 domain [IPR001452]", "9": "ATP-grasp fold [IPR011761]", "10": "Bromodomain [IPR001487]", "11": "K Homology domain, type 1 [IPR004088]", "12": "Zinc finger, RING-type [IPR001841]", "13": "Ubiquitin-like domain [IPR000626]", "14": "BRCT domain [IPR001357]", "15": "Zinc finger, PHD-type [IPR001965]", "16": "Double-stranded RNA-binding domain [IPR014720]", "17": "GTP binding domain [IPR006073]", "18": "Zinc finger, PHD-finger [IPR019787]", "19": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "20": "Helicase, C-terminal [IPR001650]", "21": "Forkhead-associated (FHA) domain [IPR000253]", "22": "DEAD/DEAH box helicase domain [IPR011545]", "23": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "24": "Protein kinase domain [IPR000719]", "25": "Small GTP-binding protein domain [IPR005225]", "26": "Domain of unknown function DUF1605 [IPR011709]", "27": "Helicase-associated domain [IPR007502]", "28": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "29": "Ubiquitin specific protease domain [IPR028889]", "30": "Thiolase, C-terminal [IPR020617]", "31": "Thiolase, N-terminal [IPR020616]", "32": "FERM central domain [IPR019748]", "33": "Band 4.1 domain [IPR019749]", "34": "FERM domain [IPR000299]", "35": "FERM, N-terminal [IPR018979]", "36": "FERM, C-terminal PH-like domain [IPR018980]"}