diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b74e901012e32a0a5c532c98df81186bd896748e --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f166defb09d8533f0671a7fd9eb960a371627d439135926c626413bc41bdd8d +size 86200 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..efc419be8a6b1b8bd602994ddec80a1ee712aba6 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cysteine peptidase, cysteine active site [IPR000169] 3 5 2.3995143899469378 0.0164168345457844 1.9927184466019416 4.106796116504855 -0.4055096631049736 0.4078826502023353 1.2157723137108922 1.0442874781746152 1.1544656254210668 0.3023405414752508 0.0031158708456652 0.0526645480715484 0.0047533286028597 0.0020298329670106 9.569573614901708e-05 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..273bc1c1ff1489c993d628f9b2a87ebf6c5c8eb8 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 59, + "title": "Average number of proteins per term", + "value": 2.7457627118644066 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..652dc866de0fe16686aa98aaa17911b227c8d8e7 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..deec888a800046e257bd70e7cf6e8c7df3e791e9 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cysteine peptidase, asparagine active site [IPR025661] 0.983475951608142 2.9059924759417184 0.0036609025190548 0.1945785364156051 0.020672404734601 2 P07858 1 +Cysteine peptidase, histidine active site [IPR025660] 0.983475951608142 2.9059924759417184 0.0036609025190548 0.1945785364156051 0.020672404734601 2 P07858 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.9802243211334112 2.88985650263711 0.0038541771539086 0.2037450013833707 0.020672404734601 3 Q9HB40,Q9H3G5 2 +Cysteine peptidase, cysteine active site [IPR000169] 0.8656617656628145 2.3995143899469378 0.0164168345457844 0.6234227062436161 0.0484296619100641 5 P53634,P07858,P17655 3 +Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.8017114192977288 2.1335491302584386 0.032879705869266 0.8608928981326678 0.0843435933168128 2 Q7LG56 1 +Nucleoside diphosphate kinase, active site [IPR023005] 0.7390687253029664 1.8441856109907555 0.0651560946276488 0.981223832051501 0.1423781327048622 3 O75414 1 +Tyrosine-protein kinase, active site [IPR008266] 0.5953230385847836 1.1525824474857698 0.2490818110984025 0.9999999542948838 0.3194744968436032 5 Q15375 1 +Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4405429330185889 0.4825018744006128 0.6294494671934632 1.0 0.687731825266932 2 P18669 1 +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.4117473435655258 0.3596396317286583 0.7191166420768127 1.0 0.7714160342278537 3 Q9UBT2,P22314 2 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.3546575392146016 0.1462878663972326 0.8836941440265229 1.0 0.8989302499580146 6 P68036,P60604 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9bd077710895a6ebfdcbc76a8a1622806160233f --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 18 (GH18) active site [IPR001579]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADA", "ADSS", "AKT1", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CASP7", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTBS", "CTSA", "CTSB", "CTSC", "DAPK3", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "NME6", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TP53RK", "TPI1", "TPP2", "TTK", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["CAPN2", "CPVL", "CTSB", "CTSC", "EPHA7", "NME6", "PGAM1", "RRM2B", "SCPEP1", "UBA1", "UBA2", "UBE2G2", "UBE2L3"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f0e3c40f3b1377b759eee53732c3a3aa39398e90 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df09c042b49f12b859d9a730b1cbc133574f26c35a3a908cf5a10451b9a96bd7 +size 77005 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3ebbb8c698f81d63992906f158809704a4f08f94 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.741935483870968 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..09edc6d5b31e89fefb97d61d0f44e773066489fb --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db0aec2f342a22bb8407b93642b86949432208f1 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.7409265269991161 1.859989145464012 0.0628870616853012 0.8664788835267917 0.2708293603380316 2 P50579 1 +Beta tubulin, autoregulation binding site [IPR013838] 0.6535735380980442 1.4298436710501838 0.1527618919201394 0.9941363244170692 0.338258474966023 5 Q13885,P04350,P68371,Q9BUF5 4 +Peptidase M16, zinc-binding site [IPR001431] 0.5690146715451876 1.0275701868298903 0.304152054153763 0.9999868796676726 0.4621716714050567 5 P22695 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5872ffacc72fbea82d62d426c24c1ac4301222f3 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Legume lectin, beta chain, Mn/Ca-binding site [IPR019825]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARAF", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DAPK3", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "LETM1", "LRP2", "MACF1", "MAP2K1", "MAP2K2", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["METAP2", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2d87a456c859f7d763df70f2e8915263713ecf7 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fdd309f058f27c4491a62bb47454402f297ccf0e --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6daa5cd8ece1efc3c6a4fbba680aab9d9a0680b65323f79c198d2b336ad033e2 +size 197197 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2d87a456c859f7d763df70f2e8915263713ecf7 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..feda66ddf11aa57d41690445d236fd5690d3613b --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34f7c18747050d6bb8c4529cae8a517cfc3ea7ec4be55f7471d40edcdb9d1a20 +size 144523 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e84a4441bd0bc1301d114a689174f1e2867adc3d --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:333d280d80804df84bea2fee972949c874ace73f480fa054bab9408f44f275b6 +size 126000 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c86acc7b8eef4e8080de08c2d5fd59f8874b69df --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Syntaxin/epimorphin, conserved site [IPR006012] 4 7 2.2172642791732105 0.0266050373514232 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 1.0 1.0 1.0 0.0033939033653995 0.0002457979454447 +Proteasome beta-type subunit, conserved site [IPR016050] 6 8 2.038113821304093 0.0415385512449792 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0748668240169799 1.0 0.0921025797166938 6.393058955734768e-05 5.436360967141595e-05 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bd8dcf2f6bf56d70ca710195052e207ca946f9e0 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 290, + "title": "Average number of proteins per term", + "value": 2.720689655172414 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4f7bbc4e5af558cd09d2e729d2ac13c4044aa292 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b3cfe4e558201b27d01d44d39a94ff56a66e9b4c --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,42 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.5995740168139485 0.0542659977417915 2 P05067 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.5995740168139485 0.0542659977417915 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.5995740168139485 0.0542659977417915 2 P05067 1 +Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415] 0.991147831218648 2.9371013021284593 0.0033129586355289 0.6180070033113748 0.0542659977417915 2 P98164 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9864266745352608 2.917971256658083 0.0035231682474297 0.6406731553819924 0.0542659977417915 2 P04066 1 +C-type lectin, conserved site [IPR018378] 0.9852463853644136 2.913181824584142 0.0035776621955889 0.6463269665424509 0.0542659977417915 2 Q5KU26 1 +Sulfatase, conserved site [IPR024607] 0.9843611684862776 2.909587930744343 0.0036190556700452 0.6505622642838453 0.0542659977417915 2 P34059 1 +EGF-like calcium-binding, conserved site [IPR018097] 0.9822904368358906 2.8982953765737274 0.0037519704859774 0.6638230991719871 0.0542659977417915 3 P98164,Q07954 2 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.979049867217468 2.887991751559385 0.003877100394259 0.6758485360522248 0.0542659977417915 2 P13473 1 +Tetraspanin, conserved site [IPR018503] 0.961345529654761 2.8155958390688927 0.0048686872846679 0.757163671137872 0.0542659977417915 2 O60637 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.934493951018 2.7045819002676157 0.00683904083361 0.8633230179496518 0.0561948934527885 2 P01889 1 +Heavy-metal-associated, conserved site [IPR017969] 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9037785105628016 0.0561948934527885 2 P35670 1 +Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.96247597027158 0.0572259443430667 2 P23229 1 +Cadherin conserved site [IPR020894] 0.8937426210153407 2.528804101724171 0.0114451888686133 0.9645007902636286 0.0572259443430667 3 Q14126,Q14574 2 +Ras GTPase-activating protein, conserved site [IPR023152] 0.8598795291684758 2.383179295958476 0.0171638324082079 0.9934002476324942 0.0711073056911472 3 P21359 1 +Sterol reductase, conserved site [IPR018083] 0.8436116848627789 2.317736282944104 0.0204636578498489 0.9975113688620348 0.072371472883612 2 Q9UBM7 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.8260573096944847 2.2172642791732105 0.0266050373514232 0.999598359607136 0.0845890000957934 7 O43752,Q13277,O15400,Q13190 4 +Proteasome beta-type subunit, conserved site [IPR016050] 0.7872809077831159 2.0381138213040932 0.0415385512449792 0.9999954642582746 0.1098698139088841 8 P28070,P49721,P49720,P20618,P28074,P28072 6 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.7716140454411362 1.9990114997876371 0.045607109624919 0.9999986790490796 0.1140177740622977 2 O60573 1 +Histidine triad, conserved site [IPR019808] 0.7671879610504525 1.9790730423751943 0.0478077830954026 0.999999323696067 0.1180876473842712 2 Q9BX68 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.7696176891809451 1.9769307667905005 0.0480494565218758 0.999999371692879 0.1180876473842712 4 Q8N4Q0 1 +Tubulin, conserved site [IPR017975] 0.6943209065199312 1.6151929971341814 0.1062689066034392 0.9999999999999928 0.2054532194333158 6 P23258,Q13885,Q9BUF5 3 +Ubiquitin interacting motif [IPR003903] 0.6792675723567475 1.5513962212937784 0.120806760228842 1.0 0.2255769245973565 5 O14964,Q92783,P42566,Q9Y6I3 4 +14-3-3 protein, conserved site [IPR023409] 0.6515615639859479 1.4124563950241285 0.1578156212857457 1.0 0.2660844777492225 6 P31946,P62258,Q04917 3 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.6400118028917113 1.3917275581506592 0.1640049138925383 1.0 0.2714556287886196 2 P11216 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.6358807907937473 1.372293427121995 0.1699721109794996 1.0 0.2753738110841054 2 P28340 1 +Cullin, conserved site [IPR016157] 0.6039269850572064 1.1848846972188567 0.2360630386224949 1.0 0.3440114633192136 6 Q13619,Q13620 2 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.5101799940985541 0.784516729360972 0.4327369695294853 1.0 0.5060230692078659 2 Q9UBT2 1 +Phosphofructokinase, conserved site [IPR015912] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.5522972884037871 3 P08237,Q01813 2 +Aldo/keto reductase, conserved site [IPR018170] 0.4791974033638324 0.6460738908538882 0.5182315032712097 1.0 0.598304540967408 2 P14550 1 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.4786072587784054 0.6434902875601908 0.5199060149096097 1.0 0.598304540967408 2 P12268 1 +Dynein light chain, type 1/2, conserved site [IPR019763] 0.4762466804367167 0.6331789606256825 0.5266167833734925 1.0 0.6036318860802878 2 Q96FJ2 1 +Ribosomal protein L3, conserved site [IPR019926] 0.4668043670699419 0.5923226654511534 0.5536345411397807 1.0 0.6321024288603796 2 P39023 1 +GTP1/OBG, conserved site [IPR006074] 0.4547064030687548 0.5409771307590003 0.5885233457389152 1.0 0.6666866025948649 2 P55039 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4510035419126305 0.5145823820315548 0.6068448789784309 1.0 0.6818904247221975 3 P08238,P07900 2 +S100/Calbindin-D9k, conserved site [IPR001751] 0.4476246680436708 0.5115032837024763 0.6089986896656867 1.0 0.6818904247221975 2 P60903 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.4386068476977546 0.4638062365109973 0.642786574759256 1.0 0.7142073052880623 3 P21912,O00217 2 +Guanylate kinase, conserved site [IPR020590] 0.4324830966463481 0.4084478410859581 0.6829449163140724 1.0 0.7473736820040792 6 Q8N3R9,Q14168 2 +DnaJ domain, conserved site [IPR018253] 0.4176503935851051 0.3160975512261646 0.7519284653656282 1.0 0.8076268702075265 10 Q99543,O60884,Q9UBS4 3 +Profilin conserved site [IPR027310] 0.3502508114488002 0.1701337181734154 0.8649049767887156 1.0 0.8960951888449695 2 P35080 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.3023467883291554 0.0197306019516567 0.9842582787006224 1.0 0.9910934056360434 8 Q9UNP9 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4eb28b0f6da5e462d6fa7a46418b3488c10d9d8e --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site [IPR020611]", "Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site [IPR014783]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7A", "ATP7B", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD4", "BTRC", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXD11", "HOXD13", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ITGA6", "ITGAV", "IVD", "KDM5A", "KDSR", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRP2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAM", "PATZ1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["AKR1A1", "APP", "ATP7B", "COLEC12", "CUL4A", "CUL4B", "DHCR7", "DNAJA2", "DNAJB11", "DNAJC2", "DRG2", "DSC3", "DSG2", "DYNLL2", "EIF4E2", "EPN1", "EPS15", "FUCA1", "GALNS", "HGS", "HINT2", "HLA-B", "HSP90AA1", "HSP90AB1", "IMPDH2", "ITGA6", "LAMP2", "LRP1", "LRP2", "MPP2", "MPP5", "NDUFS8", "NF1", "PFKM", "PFKP", "PFN2", "POLD1", "PPIE", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PYGB", "RPL3", "S100A10", "SDHB", "STAM", "STX3", "STX5", "STX6", "STX7", "TSPAN3", "TUBB2A", "TUBB6", "TUBG1", "UBA2", "YWHAB", "YWHAE", "YWHAH", "ZADH2"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..77ea1800f5e8b49fc487ea07eb190d776febe0bf --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Immunoglobulin-like domain [IPR007110]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..19fe2e81cd838528239ea14a03264bfd7bf0b163 --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a1986475f88ef150ca3372bdd19d3ec4007c7c42ca05891bce68130d3fae662 +size 195485 diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..74242d58f788f8397dae0bad0050fe3b8c76ced4 --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Immunoglobulin-like domain [IPR007110]", "1": "Target SNARE coiled-coil homology domain [IPR000727]", "2": "LIS1 homology motif [IPR006594]", "3": "EF-hand domain [IPR002048]", "4": "von Willebrand factor, type A [IPR002035]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ef665bac6d7670a7b9597649d35a3848a33dcda2 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a380bbfa5f771edb9af81bfc531ec9d20c90d64f8b6ca784120b5ac226da5c5b +size 136515 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a42eed86943ab2d647307952283752f13ed9bf1f --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba9c8dcafeccc8b71de94361761867d382e5090fcd3f7f7b744363a737464c11 +size 138561 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..c94bb312abe70b1f8668cd67df0a1f44d1413439 --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d67e1336aa524716c4a3eddb46293c5ad8fcfd3f6d266a676fe02e99f36acfae +size 137860 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5ee3530ba77a0eba1e163f5a5f5ea71faa21d9b7 --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:988bf7a550f398432976608e3e40998f1067f85b41671a7ef0c9f728bb29f479 +size 139784 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..a72835e98498422eeefac5edbb930820d95ca017 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:924565e87711084bbd20aedec1f5dc3651b7ec55e55c5c6ed5e4891fd4809a73 +size 147522 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..290bed766bb254fd5bcad45a90dbd44eeb1a5f66 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a47682a3365f9acc8295d3c1668a0357e0b89760bdaa53d65a41cf529ba5100f +size 502797 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..36d131d0d2cc8c7ae4cad44296d133f662532875 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EGF-like domain [IPR000742] 3 5 2.875378173992592 0.0040354384043617 1.812807881773399 3.940886699507389 -0.2515571357977262 0.397990648527913 1.5407225921455587 2.4527963737747185 1.3250723622342764 0.3076599741691995 0.0209998346349405 0.0060673937801388 0.0060698672163979 0.1135382716428265 0.5077964068323771 +Ricin B, lectin domain [IPR000772] 3 5 2.649326682357421 0.0080652328516972 1.4174757281553398 4.121359223300971 0.4009585995426035 0.4855340701643459 1.119329478938434 0.8894364404712861 0.9609441077042546 0.3172385378622441 0.1101969479300293 1.0 0.1349531130589082 0.0003774704498572 0.0048822579474643 +Aminopeptidase N-like , N-terminal domain [IPR045357] 3 6 2.48325259861364 0.0130188732853997 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0603501083335805 0.0385773062479974 0.0743799864466655 0.014977467250991 0.0003286021100258 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 6 2.48325259861364 0.0130188732853997 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0603501083335805 0.0385773062479974 0.0743799864466655 0.014977467250991 0.0003286021100258 +Immunoglobulin subtype 2 [IPR003598] 4 10 2.268579068740088 0.0232939356731132 2.8106796116504853 8.04126213592233 0.1764352420775828 0.5005828106358552 2.0581551085254395 2.677802743524345 1.0491539805619012 0.3137632145774063 0.0156421300540138 0.2849410889163232 0.0275216398495969 0.0246198078338957 0.1114390039799233 +Fibronectin type III [IPR003961] 3 7 2.130791912907537 0.0331062888974305 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.425452185951316 0.295480255529908 0.497470817800254 0.5185914106235352 0.4545916116320574 +Immunoglobulin-like domain [IPR007110] 8 15 2.036116462428891 0.0417386620312951 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.0571855146636762 0.4279811411777856 0.0948939281427919 0.0017059946057754 0.0476335979538943 +Immunoglobulin V-set domain [IPR013106] 3 5 2.015755057831676 0.0438255951852522 1.8814814814814815 3.639506172839506 -0.1240957684542258 0.411362008796823 1.3951513136318474 1.5958030613003984 1.3078070990153907 0.3212718057023477 0.0283352543336475 1.0 0.0420348553288257 0.0089321887950908 0.0807266025333323 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..96bd7ff901ca0d82011bea06fc245a4feaf7ffb2 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 2702, + "title": "Average number of proteins per term", + "value": 2.2005921539600295 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a8a75878c058642e83540535627b3625033d2f85 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..18afbd3e15cbdb66c89865f450f5258655eac8bc --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,257 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9998020279565302 0.0666092070819174 2 P05067 1 +Complement Clr-like EGF domain [IPR026823] 0.991147831218648 2.9371013021284593 0.0033129586355289 0.9998723827781508 0.0666092070819174 2 P98164 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9864266745352608 2.917971256658083 0.0035231682474297 0.9999278244833572 0.0666092070819174 2 P04066 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.9852463853644136 2.913181824584142 0.0035776621955889 0.9999377391012372 0.0666092070819174 2 Q5KU26 1 +C-type lectin-like [IPR001304] 0.9852463853644136 2.913181824584142 0.0035776621955889 0.9999377391012372 0.0666092070819174 2 Q5KU26 1 +Sulfatase, N-terminal [IPR000917] 0.9843611684862776 2.909587930744343 0.0036190556700452 0.9999443498640832 0.0666092070819174 2 P34059 1 +Peptidase C1A, papain C-terminal [IPR000668] 0.983475951608142 2.9059924759417184 0.0036609025190548 0.9999503200586374 0.0666092070819174 2 P07858 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.9820005901445836 2.899996579669356 0.0037316673202281 0.9999589953535332 0.0666092070819174 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.9820005901445836 2.899996579669356 0.0037316673202281 0.9999589953535332 0.0666092070819174 2 Q13641 1 +EGF-like calcium-binding domain [IPR001881] 0.9822904368358906 2.8982953765737274 0.0037519704859774 0.9999611922413872 0.0666092070819174 3 P98164,Q07954 2 +Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.9772794334611968 2.880780499273083 0.0039669179765118 0.9999783375171076 0.0666092070819174 2 P06865 1 +Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.9772794334611968 2.880780499273083 0.0039669179765118 0.9999783375171076 0.0666092070819174 2 P06865 1 +MD-2-related lipid-recognition domain [IPR003172] 0.9763942165830602 2.877172519967533 0.0040125615525274 0.9999808604112096 0.0666092070819174 2 P17900 1 +EGF-like domain [IPR000742] 0.9778148558230344 2.875378173992592 0.0040354384043617 0.999982012161218 0.0666092070819174 5 P98164,Q08431,Q07954 3 +PA domain [IPR003137] 0.9760920897284522 2.872953040858597 0.0040665455687758 0.9999834679243774 0.0666092070819174 3 Q8TCT8,P02786 2 +Fibronectin type II domain [IPR000562] 0.9632885237538558 2.820359613326383 0.0047969857951211 0.9999977229808386 0.0666092070819174 3 P11717 1 +Glycoside hydrolase family 2, catalytic domain [IPR006103] 0.9501327825317176 2.769417336574836 0.005615665233053 0.9999997535957512 0.0666092070819174 2 O00462 1 +Immunoglobulin [IPR013151] 0.9465919150191762 2.7547814667411172 0.0058731348946525 0.9999998776028514 0.0666092070819174 2 P43121 1 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.942165830628501 2.7364505867759807 0.0062105921497752 0.9999999510930728 0.0666092070819174 2 P31749 1 +Galactosyltransferase, C-terminal [IPR027791] 0.938920035408676 2.7229824322331795 0.0064695498035527 0.9999999758145556 0.0666092070819174 2 O60512 1 +Galactosyltransferase, N-terminal [IPR027995] 0.938920035408676 2.7229824322331795 0.0064695498035527 0.9999999758145556 0.0666092070819174 2 O60512 1 +MHC class I-like antigen recognition-like [IPR011161] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9999999923380058 0.0668452728696975 3 P10321,P01889 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9999999923380058 0.0668452728696975 3 P10321,P01889 2 +Immunoglobulin C1-set [IPR003597] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9999999923380058 0.0668452728696975 3 P10321,P01889 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9999999923380058 0.0668452728696975 3 P10321,P01889 2 +N-acetylgalactosaminyltransferase [IPR045885] 0.9285714285714268 2.6760687406309196 0.0074491364986466 0.99999999831737 0.0668452728696975 3 Q86SF2,Q10472 2 +Heavy metal-associated domain, HMA [IPR006121] 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9999999996635656 0.0668452728696975 2 P35670 1 +Heavy metal-associated domain, copper ion-binding [IPR006122] 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9999999996635656 0.0668452728696975 2 P35670 1 +Ricin B, lectin domain [IPR000772] 0.9237635318709896 2.6493266823574215 0.0080652328516972 0.9999999996856817 0.0668452728696975 5 Q86SF2,Q10472,Q9UBG0 3 +Glycoside hydrolase family 38, central domain [IPR015341] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.999999999756366 0.0668452728696975 2 O00754 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.999999999756366 0.0668452728696975 2 O00754 1 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.999999999756366 0.0668452728696975 2 O00754 1 +Peptidase C2, calpain, domain III [IPR022683] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9999999999240238 0.0668452728696975 2 P17655 1 +Calpain subdomain III [IPR033883] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9999999999240238 0.0668452728696975 2 P17655 1 +Peptidase C2, calpain, catalytic domain [IPR001300] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9999999999240238 0.0668452728696975 2 P17655 1 +Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9999999999240238 0.0668452728696975 2 P17655 1 +Glycosyl transferase 64 domain [IPR015338] 0.9126586013573256 2.613214019669035 0.0089695114549768 0.9999999999732628 0.0668452728696975 2 Q93063 1 +Exostosin, GT47 domain [IPR040911] 0.9126586013573256 2.613214019669035 0.0089695114549768 0.9999999999732628 0.0668452728696975 2 Q93063 1 +ERAP1-like C-terminal domain [IPR024571] 0.9096545615589108 2.5926826621178605 0.0095230595725133 0.9999999999940914 0.0668452728696975 4 Q9UIQ6,Q6P179,Q9NZ08 3 +EXPERA domain [IPR033118] 0.8973148421363148 2.5484167917419267 0.0108213098361538 0.9999999999998292 0.0697832438598749 2 Q5BJF2 1 +Domain of unknown function DUF5600 [IPR040990] 0.894364119209208 2.535899385868316 0.0112158953412879 0.999999999999942 0.0704542855183163 2 Q9H223 1 +EH domain-containing protein, N-terminal [IPR031692] 0.894364119209208 2.535899385868316 0.0112158953412879 0.999999999999942 0.0704542855183163 2 Q9H223 1 +Integrin alpha-2 [IPR013649] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.999999999999948 0.0704542855183163 2 P23229 1 +Cadherin prodomain [IPR014868] 0.8934789023310592 2.532140608558323 0.0113368519850785 0.9999999999999584 0.0705810462296823 2 Q14574 1 +Cadherin, cytoplasmic domain [IPR000233] 0.8934789023310592 2.532140608558323 0.0113368519850785 0.9999999999999584 0.0705810462296823 2 Q14574 1 +Cadherin-like [IPR002126] 0.8937426210153407 2.528804101724171 0.0114451888686133 0.9999999999999688 0.0709286704655808 3 Q14126,Q14574 2 +HDGF-related, PWWP domain [IPR035496] 0.8910170919940108 2.5171726994714367 0.0118300826747201 0.9999999999999892 0.0719659018114675 3 Q7Z4V5 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8857290110049938 2.48325259861364 0.0130188732853997 0.9999999999999996 0.0731802814506346 6 Q9UIQ6,Q6P179,Q9NZ08 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8857290110049938 2.48325259861364 0.0130188732853997 0.9999999999999996 0.0731802814506346 6 Q9UIQ6,Q6P179,Q9NZ08 3 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8772499262319238 2.462938325151771 0.0137803617904346 1.0 0.0740882915558188 2 O15460 1 +Glycosyl hydrolase, family 13, catalytic domain [IPR006047] 0.8474476246680297 2.3344147666499637 0.0195740143142382 1.0 0.0845877054119034 2 P08195 1 +Immunoglobulin subtype 2 [IPR003598] 0.8390258243174702 2.268579068740088 0.0232939356731132 1.0 0.0918487013110857 10 P43121,Q9BY67,Q9Y624,Q92859 4 +NECAP, PHear domain [IPR012466] 0.8303334316907529 2.2597642646419995 0.0238358853822768 1.0 0.0933363011028908 2 Q9NVZ3 1 +Syntaxin, N-terminal domain [IPR006011] 0.8196902885194698 2.2018236140940024 0.0276777703577708 1.0 0.1010612641982389 4 O15400,Q13277 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8166395100256003 2.1937131521989595 0.0282560377114833 1.0 0.1020692699150106 3 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8166395100256003 2.1937131521989595 0.0282560377114833 1.0 0.1020692699150106 3 Q9Y282 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8114488049572166 2.1766794194523604 0.0295044948983009 1.0 0.1046209254792772 2 Q7L576 1 +Peptidase M20, dimerisation domain [IPR011650] 0.8067276482738276 2.155792249979711 0.0310998909163167 1.0 0.1071835526223058 2 Q8IYS1 1 +GINS subunit, domain A [IPR021151] 0.805904530926056 2.1460681241157205 0.0318675439712294 1.0 0.1076226376129801 3 Q9BRX5 1 +JmjC domain [IPR003347] 0.8026854563225105 2.1317343293913695 0.0330286929783425 1.0 0.1104338617586319 3 Q7LBC6 1 +Fibronectin type III [IPR003961] 0.806859033388942 2.130791912907537 0.0331062888974305 1.0 0.1104338617586319 7 Q15375,Q92859,P08069 3 +Cold-shock (CSD) domain [IPR019844] 0.7971773690037369 2.1013468251297676 0.0356105321241784 1.0 0.1140487557072499 4 P67809 1 +Immunoglobulin I-set [IPR013098] 0.7922347255800573 2.079147117356766 0.037603830521613 1.0 0.1160947507651065 4 Q92859 1 +Immunoglobulin-like domain [IPR007110] 0.7896658231008764 2.036116462428891 0.0417386620312951 1.0 0.1235244959568012 15 Q08722,Q9BY67,P10321,Q92859,P43121,P01889,P78310,Q9Y624 8 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.7786957804662071 2.030832037144408 0.0422720359320329 1.0 0.1245572967157613 2 O15027 1 +Immunoglobulin V-set domain [IPR013106] 0.7794660131737572 2.015755057831676 0.0438255951852522 1.0 0.126245481290326 5 P43121,Q9BY67,Q9Y624 3 +Ras GTPase-activating domain [IPR001936] 0.7774428257163695 2.0124124427692855 0.0441764779366744 1.0 0.1263564929769534 4 P21359 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.7759740259740138 2.011975894918629 0.0442224780554134 1.0 0.1263564929769534 3 Q9BYT8,P52888 2 +Zinc finger, C3HC4 RING-type [IPR018957] 0.7772905418911539 2.0117231056591787 0.0442491335585129 1.0 0.1263564929769534 4 Q5VTR2 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.7710239008557143 1.9963552793482344 0.0458952649240824 1.0 0.1290069177051319 2 P23634 1 +GYF domain [IPR003169] 0.7683682502213041 1.9843937503575368 0.0472119621909474 1.0 0.1305020169508629 2 O95400 1 +BRO1 domain [IPR004328] 0.7651097313848506 1.9628557840233103 0.0496629337433749 1.0 0.133654628460756 3 Q5VW32 1 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.7539490946372019 1.9121547964850865 0.0558563421491893 1.0 0.1435621618605934 3 Q15375 1 +CBS domain [IPR000644] 0.7558606323365643 1.893060188889507 0.0583498656785361 1.0 0.1460226879497551 8 P51798,P51797,P51790 3 +ROCK, Rho binding domain [IPR015008] 0.7459427559752159 1.8828370672236316 0.0597224520026844 1.0 0.1485912203602701 2 Q13464 1 +NIPSNAP [IPR012577] 0.7456476836825057 1.8814943763729648 0.0599046995500214 1.0 0.1489075420277441 2 Q9BPW8 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7450778016670386 1.864882023138977 0.0621979427694938 1.0 0.1517706974782358 4 P13674,O15460 2 +Zinc finger, GRF-type [IPR010666] 0.7412215992918061 1.861334440203405 0.0626969624770676 1.0 0.1517706974782358 2 Q13472 1 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7470509888544541 1.8565522852424756 0.0633748777587972 1.0 0.1527784702484018 7 Q9BV79,Q8N4Q0 2 +Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.7400413101209835 1.8559522920521156 0.0634603584665562 1.0 0.1527784702484018 2 Q9UBF2 1 +Coatomer subunit gamma, C-terminal [IPR032154] 0.7400413101209835 1.8559522920521156 0.0634603584665562 1.0 0.1527784702484018 2 Q9UBF2 1 +Nucleoside diphosphate kinase-like domain [IPR034907] 0.7390687253029664 1.8441856109907555 0.0651560946276488 1.0 0.1554825830401409 3 O75414 1 +CD80-like, immunoglobulin C2-set [IPR013162] 0.738483304883891 1.8415031281970449 0.0655478625935011 1.0 0.156181944204268 3 Q9BY67 1 +MRH domain [IPR044865] 0.7378610192113669 1.831712696813559 0.0669942360113431 1.0 0.1580946949368114 4 P11717 1 +Chaperone DnaJ, C-terminal [IPR002939] 0.7363958583851304 1.8183301380417844 0.069013689101316 1.0 0.1614502060188362 5 O60884 1 +Immunoglobulin subtype [IPR003599] 0.7415922572245947 1.8152796176630135 0.0694809496529025 1.0 0.1622623387745398 11 P43121,Q9BY67,Q9Y624,Q92859 4 +Pre-PUA domain [IPR041366] 0.7300088521687809 1.8101008042362348 0.0702801562981552 1.0 0.1632820140306237 2 P41214 1 +Fatty acid desaturase domain [IPR005804] 0.7270581292416657 1.7965804378726018 0.072402252279101 1.0 0.1660703613396697 2 O15121 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.7257358893302078 1.752202916117579 0.0797389224085507 1.0 0.1753088432448365 8 Q9H223,Q9UQ16,Q9H4M9 3 +Dynamin, N-terminal [IPR045063] 0.7257358893302078 1.752202916117579 0.0797389224085507 1.0 0.1753088432448365 8 Q9H223,Q9UQ16,Q9H4M9 3 +RUN domain [IPR004012] 0.7123045146060774 1.728750154407007 0.0838538207321997 1.0 0.1793927344563765 2 Q7L099 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.7223707268544387 1.723891599757476 0.0847274140754998 1.0 0.1801484179447018 11 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +Glycosyltransferase 2-like [IPR001173] 0.7138233575387611 1.713490031341952 0.0866224257510164 1.0 0.1820618224995388 5 Q86SF2,Q10472 2 +CTP synthase GATase domain [IPR033828] 0.699026261434052 1.667391428386488 0.0954365971676423 1.0 0.1940177557303783 2 P17812 1 +CTP synthase, N-terminal [IPR017456] 0.699026261434052 1.667391428386488 0.0954365971676423 1.0 0.1940177557303783 2 P17812 1 +PWI domain [IPR002483] 0.701493035701237 1.655858399258815 0.0977504979404693 1.0 0.1965245066436869 5 O43395 1 +Dynamin, GTPase domain [IPR001401] 0.6966083757128174 1.640355415165983 0.1009312897827439 1.0 0.2018625795654878 4 Q9UQ16 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.2094099585803859 6 P23258,Q13885,Q9BUF5 3 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.2094099585803859 6 P23258,Q13885,Q9BUF5 3 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.6792564178223673 1.5755333975520978 0.1151333758073565 1.0 0.219982027425684 2 P52701 1 +DNA mismatch repair protein MutS, core [IPR007696] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2206769981442465 3 P52701,P20585 2 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2206769981442465 3 P52701,P20585 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2206769981442465 3 P52701,P20585 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2206769981442465 3 P52701,P20585 2 +EF-hand, Ca insensitive [IPR014837] 0.676713385964681 1.555198212167495 0.1198988699807568 1.0 0.2241984406145363 3 P12814 1 +PTB/PI domain [IPR006020] 0.6771395190610066 1.5491169936870637 0.1213535984882936 1.0 0.2258246715670588 4 O60343,Q9Y3P9 2 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.6820134862686268 1.5346190563626263 0.1248774289329683 1.0 0.2303200088579389 10 P35670,Q04656,Q9NQ11,Q8NB49 4 +EF-hand domain, type 2 [IPR015154] 0.6686338152847257 1.5259533188103394 0.1270214905366007 1.0 0.23127497805249 2 Q9Y4J8 1 +EF-hand domain, type 1 [IPR015153] 0.6686338152847257 1.5259533188103394 0.1270214905366007 1.0 0.23127497805249 2 Q9Y4J8 1 +Zinc finger, ZZ-type [IPR000433] 0.6686338152847257 1.5259533188103394 0.1270214905366007 1.0 0.23127497805249 2 Q9Y4J8 1 +Exosome complex component, N-terminal domain [IPR025721] 0.6665683092357653 1.5162962901199992 0.1294444493149624 1.0 0.2344228566012256 2 Q9Y3B2 1 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.6664168072811129 1.5069240532196138 0.1318301252437246 1.0 0.2379458907204702 3 Q10567 1 +Nucleotidyl transferase domain [IPR005835] 0.6653743949970214 1.502029694162643 0.1330894402228786 1.0 0.2391008427408364 3 Q9NR50 1 +HR1 rho-binding domain [IPR011072] 0.6634189548272935 1.4845186080155433 0.137671390305794 1.0 0.2435413826448496 4 Q5T0N5,O75116,Q13464 3 +LEM-like domain [IPR013146] 0.6568309235762793 1.470703906518813 0.1413712092858539 1.0 0.2452785045686787 2 P42166 1 +Tim44-like domain [IPR007379] 0.6550604898200079 1.4624032782572247 0.1436307316270331 1.0 0.2479809820167689 2 Q9BRJ2 1 +ERM family, FERM domain C-lobe [IPR041789] 0.6519069355790504 1.438690337008073 0.1502382783386799 1.0 0.2548297728004478 3 P15311 1 +14-3-3 domain [IPR023410] 0.6515615639859479 1.4124563950241285 0.1578156212857457 1.0 0.2622920992905737 6 P31946,P62258,Q04917 3 +PUA domain [IPR002478] 0.6451073230003905 1.397989388211245 0.1621162538668157 1.0 0.2670964133830097 4 P41214,Q9Y221 2 +Beta-Casp domain [IPR022712] 0.6384487596265436 1.3752238124713052 0.1690620680224328 1.0 0.2732187031527128 3 Q5TA45 1 +Cold shock domain [IPR011129] 0.6312021672717889 1.3235088918774558 0.1856662012441563 1.0 0.2884435462484148 5 P67809 1 +Cold-shock protein, DNA-binding [IPR002059] 0.6312021672717889 1.3235088918774558 0.1856662012441563 1.0 0.2884435462484148 5 P67809 1 +PWWP domain [IPR000313] 0.6361446550057254 1.3187585649958211 0.1872498406455762 1.0 0.2904414864663301 9 P51858,Q7Z4V5 2 +BTB/POZ domain [IPR000210] 0.6301574887649583 1.303092110858716 0.1925433166600698 1.0 0.2961024710389919 7 Q08380 1 +Cullin protein, neddylation domain [IPR019559] 0.6039269850572064 1.1848846972188567 0.2360630386224949 1.0 0.3362373908054724 6 Q13619,Q13620 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.5848332841546233 1.131663732560081 0.257775834557628 1.0 0.3582871939170323 2 Q92945 1 +Ras-associating (RA) domain [IPR000159] 0.5828166519043548 1.1024578365851423 0.2702626792033915 1.0 0.3686336406248111 4 Q15036,Q9Y4G8,P55196 3 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.5793058066221064 1.0858274786910496 0.2775553267517976 1.0 0.3772406905851897 4 P10586 1 +CARP motif [IPR006599] 0.5718501032753109 1.070569650509598 0.2843629758408099 1.0 0.3824533403294517 2 O75695 1 +C-CAP/cofactor C-like domain [IPR017901] 0.5718501032753109 1.070569650509598 0.2843629758408099 1.0 0.3824533403294517 2 O75695 1 +Fzo/mitofusin HR2 domain [IPR006884] 0.5694895249336112 1.0594788803846895 0.2893817425831804 1.0 0.3857981273222296 2 O95140 1 +VHS domain [IPR002014] 0.5701572616412385 1.042551332834916 0.297156139178429 1.0 0.3932007287267948 4 O60784 1 +ATPase, dynein-related, AAA domain [IPR011704] 0.5656535851283628 1.0414705292250956 0.2976572239983177 1.0 0.3932545685625564 2 A3KMH1 1 +Band 7 domain [IPR001107] 0.5752037330624021 1.0396036379947893 0.2985240860298641 1.0 0.3932774648721077 7 P27105 1 +SGNH hydrolase-type esterase domain [IPR013830] 0.5654976992369898 1.0304694687952436 0.3027896772833354 1.0 0.3963845484590951 3 P68402 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.5628689492325756 1.0181062245965071 0.3086274775383559 1.0 0.4013048336422704 3 P28340,P09884 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.5628689492325756 1.0181062245965071 0.3086274775383559 1.0 0.4013048336422704 3 P28340,P09884 2 +CLASP N-terminal domain [IPR024395] 0.5503098259073514 0.9696551869483842 0.3322183947648724 1.0 0.4218299354580288 2 Q7Z460 1 +Peptidase M16, middle/third domain [IPR032632] 0.5461788138093886 0.9503933903181728 0.3419124012226384 1.0 0.429696422373753 2 P14735 1 +Sterile alpha motif domain [IPR001660] 0.5599913760987443 0.9439817062944506 0.3451789966865544 1.0 0.4323939031279879 10 Q15375,Q6UWE0 2 +Cullin homology domain [IPR016158] 0.5527816902692853 0.9329121307021886 0.3508653385558637 1.0 0.4364816504502504 7 Q13619,Q13620 2 +MOSC, N-terminal beta barrel [IPR005303] 0.5402773679551535 0.922941916097768 0.3560374753017252 1.0 0.4402806673982891 2 Q969Z3 1 +Molybdenum cofactor sulfurase, C-terminal [IPR005302] 0.5402773679551535 0.922941916097768 0.3560374753017252 1.0 0.4402806673982891 2 Q969Z3 1 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.5472897127395182 0.9069374150490408 0.3644398940555986 1.0 0.4441860281638632 7 Q15375,P08069 2 +NudC N-terminal domain [IPR025934] 0.5326054883446555 0.8873853220040536 0.3748714832060114 1.0 0.4517056863714478 2 Q8IVD9 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.541876092311204 0.8814104205908524 0.3780957195309664 1.0 0.4517056863714478 7 O75116,Q05655,Q13464,P10398 4 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.5302449100029551 0.8764777548643657 0.3807703644187779 1.0 0.4517056863714478 2 O43390 1 +Uncharacterised domain CHP00451 [IPR004521] 0.5299498377102503 0.8751154713932285 0.3815110797397074 1.0 0.4517056863714478 2 Q9ULC4 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.5392778824677502 0.8608246356916243 0.3893346344165258 1.0 0.4547210560934764 8 Q9BV79,Q8N4Q0 2 +WHEP-TRS domain [IPR000738] 0.5234720992028282 0.824146320238153 0.4098564236096751 1.0 0.4690383063253142 4 P23381,P56192,P07814 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.5314146682305521 0.8238620565176505 0.4100179420948897 1.0 0.4690383063253142 8 Q8N3R9,Q9UDY2,Q14168 3 +Guanylate kinase-like domain [IPR008144] 0.5314146682305521 0.8238620565176505 0.4100179420948897 1.0 0.4690383063253142 8 Q8N3R9,Q9UDY2,Q14168 3 +Major facilitator superfamily domain [IPR020846] 0.5258981433668162 0.815465478639469 0.4148059170878282 1.0 0.4723158819938103 6 Q7L0J3,Q14728 2 +Diaphanous autoregulatory (DAD) domain [IPR014767] 0.5168240850058948 0.8040202832415461 0.4213852609770452 1.0 0.4769932866191773 3 O60879,O60610 2 +Bicarbonate transporter, C-terminal [IPR011531] 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.4842581879075872 2 Q9Y6M7 1 +Band 3 cytoplasmic domain [IPR013769] 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.4842581879075872 2 Q9Y6M7 1 +Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.4863790730734563 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.4863790730734563 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.4863790730734563 2 A0AVT1 1 +Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.4863790730734563 2 A0AVT1 1 +ZU5 domain [IPR000906] 0.5098849218058532 0.7831757936486184 0.4335238875529608 1.0 0.4868584971604738 2 Q12955 1 +L27 domain, C-terminal [IPR014775] 0.5095866390440169 0.7604686331106931 0.4469745117535582 1.0 0.4981389253264222 4 Q14168 1 +Zinc finger, UBP-type [IPR001607] 0.5064935064935012 0.7569344406228468 0.449089140482682 1.0 0.4997688869786684 3 Q7Z569,P45974 2 +NLE [IPR012972] 0.5019179699026284 0.7471158120716286 0.4549936563579577 1.0 0.50467687170739 2 Q9NVX2 1 +HECT domain [IPR000569] 0.5115539194733625 0.7402748487371484 0.4591332389672713 1.0 0.5088507020875993 7 P46934,Q15386,O95071 3 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.5113952935892705 0.739546563043915 0.4595751763119826 1.0 0.5089230026208922 7 P13674,O15460 2 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.5113952935892705 0.739546563043915 0.4595751763119826 1.0 0.5089230026208922 7 P13674,O15460 2 +Methyltransferase type 11 [IPR013216] 0.499528016118387 0.7254602868138141 0.4681696997289788 1.0 0.5178037366629966 3 O43709 1 +Diacylglycerol/phorbol-ester binding [IPR020454] 0.4988165571983258 0.7222590643990768 0.4701352156588247 1.0 0.5193575714576321 3 P10398 1 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.4963115963411121 0.7219203630996343 0.4703434409166638 1.0 0.5193575714576321 2 Q13330 1 +Phosphofructokinase domain [IPR000023] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.5230398322487553 3 P08237,Q01813 2 +Histone deacetylase domain [IPR023801] 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.5313597171070998 2 Q13547 1 +Putative WW-binding domain and destruction box [IPR033461] 0.4912953673650106 0.6995149910383724 0.484230247768912 1.0 0.5329491362409776 2 Q9ULX3 1 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.4892298613160342 0.6903294138807042 0.4899870545887217 1.0 0.5384078981288029 2 P49588 1 +Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.4892298613160342 0.6903294138807042 0.4899870545887217 1.0 0.5384078981288029 2 P49588 1 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.488332665852887 0.6754043376302628 0.499418910410172 1.0 0.5476582369838818 3 Q99584 1 +Domain of unknown function DUF4749 [IPR031847] 0.4824431985836587 0.6603239066923513 0.5090459916959502 1.0 0.5577624775192447 2 Q96HC4 1 +Kinesin-like [IPR022164] 0.4828660146887082 0.6512274540861813 0.5148996705341495 1.0 0.5632627165114461 3 O60333 1 +Signal recognition particle SRP54, helical bundle [IPR013822] 0.4794924756565359 0.6473665464303371 0.5173947417960045 1.0 0.5653055367298035 2 P61011 1 +Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897] 0.4794924756565359 0.6473665464303371 0.5173947417960045 1.0 0.5653055367298035 2 P61011 1 +IMP dehydrogenase/GMP reductase [IPR001093] 0.4786072587784054 0.6434902875601908 0.5199060149096097 1.0 0.5675903241558649 2 P12268 1 +PurM-like, N-terminal domain [IPR016188] 0.4780171141929917 0.6409089756785704 0.5215818239397665 1.0 0.5691898579504238 2 P49903 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.4811636166412137 0.6330795047346219 0.5266817255040626 1.0 0.5738282348032165 4 Q96S59,Q9NWU2 2 +CRA domain [IPR013144] 0.4811636166412137 0.6330795047346219 0.5266817255040626 1.0 0.5738282348032165 4 Q96S59,Q9NWU2 2 +SET domain [IPR001214] 0.4793060599377886 0.6044087421829544 0.5455719249823958 1.0 0.593213417023112 6 O96028,Q9H9B1 2 +THIF-type NAD/FAD binding fold [IPR000594] 0.4787823710278919 0.5838760288313214 0.5593037218440409 1.0 0.6069231551897986 8 Q13564 1 +Domain of unknown function DUF3517 [IPR021905] 0.4603127766302779 0.5646227230944748 0.5723304061809418 1.0 0.6195660086141445 2 Q9UPU5 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.4624909758837553 0.5629172963329335 0.5734912017810676 1.0 0.6203255513260387 3 Q14241 1 +Stromalin conservative domain [IPR020839] 0.4591324874594386 0.5596227391599229 0.5757367913174833 1.0 0.622256324055936 2 Q8WVM7 1 +STAG [IPR013721] 0.4591324874594386 0.5596227391599229 0.5757367913174833 1.0 0.622256324055936 2 Q8WVM7 1 +Sec24-like, trunk domain [IPR041742] 0.4613101530708106 0.557896425306048 0.5769151126682803 1.0 0.6232805415552553 3 O95486 1 +Cullin, N-terminal [IPR001373] 0.4727101803608886 0.5573233074656554 0.5773065539835618 1.0 0.6234541602172597 8 Q13619,Q13620 2 +GTP binding protein, second domain [IPR031662] 0.4547064030687548 0.5409771307590003 0.5885233457389152 1.0 0.6342877389479337 2 P55039 1 +TOG domain [IPR034085] 0.4644265152369915 0.5399398982642748 0.5892384814247713 1.0 0.6342877389479337 6 O00410 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.4496901740926691 0.5200525842847628 0.6030269251359694 1.0 0.6465788697291228 2 Q15477 1 +rRNA-processing arch domain [IPR025696] 0.4496901740926691 0.5200525842847628 0.6030269251359694 1.0 0.6465788697291228 2 Q15477 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.4511366991437895 0.5044929690522713 0.6139150017144583 1.0 0.6579463623153124 4 P08238,Q12931,P07900 3 +Thioredoxin-like fold [IPR012336] 0.4458542342874028 0.5042072608517378 0.6141157386229525 1.0 0.6579463623153124 2 Q8NBF2 1 +CTLH, C-terminal LisH motif [IPR006595] 0.4531224641789297 0.5023540337820555 0.615418506734116 1.0 0.6590807789122399 5 Q96S59,Q9NWU2 2 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059] 0.437297137798774 0.4693772097826031 0.6388000355400001 1.0 0.6827680759608704 2 P07814 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.4387363448479504 0.4537498451909429 0.6500088863003306 1.0 0.6941992137484163 4 Q16134,O00217,P21912 3 +Glutaredoxin, PICOT-like [IPR033658] 0.4269696075538661 0.4283677027560882 0.6683834348786704 1.0 0.7129775132420716 2 O76003 1 +LIS1 homology motif [IPR006594] 0.4486418013738457 0.4140197991086786 0.6788596069082131 1.0 0.7238668736645587 13 Q9BZK7,Q96S59,Q9NWU2,Q7Z3E5,Q7L5Y9 5 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.4203069657615119 0.3918815831840747 0.6951457113347601 1.0 0.7383190691928152 3 Q08J23,Q96P11 2 +SANT/Myb domain [IPR001005] 0.4384816065241295 0.3804126137324375 0.7036391527959802 1.0 0.745581565041074 12 Q96L91 1 +L27 domain [IPR004172] 0.4224679866748974 0.3795246290105851 0.7042983185855469 1.0 0.7459874781725393 5 Q14168 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.414994096812286 0.3717569363463098 0.7100738291107289 1.0 0.7515156624587503 3 Q9BUJ2,Q1KMD3 2 +Exportin-2, central domain [IPR013713] 0.4142710354629201 0.3690462870991476 0.7120932239601203 1.0 0.7533578273845908 3 O95373 1 +Transcription factor IIS, N-terminal [IPR017923] 0.4165730134242542 0.3673310499169421 0.7133720959906784 1.0 0.7544154220613749 4 Q14241,P23193 2 +mRNA splicing factor Cwf21 domain [IPR013170] 0.4066096193567456 0.351241339090421 0.7254072992125042 1.0 0.7656447353406979 2 O15042 1 +Sec23/Sec24, helical domain [IPR006900] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.7660981565646091 4 O95486 1 +Sec23/Sec24, trunk domain [IPR006896] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.7660981565646091 4 O95486 1 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.7660981565646091 4 O95486 1 +Sec23/Sec24 beta-sandwich [IPR012990] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.7660981565646091 4 O95486 1 +Peptidase M16, N-terminal [IPR011765] 0.4182205539433438 0.3443011179089323 0.7306198436590183 1.0 0.7693432648350225 7 Q10713,P22695 2 +Peptidase M16, C-terminal [IPR007863] 0.4182205539433438 0.3443011179089323 0.7306198436590183 1.0 0.7693432648350225 7 Q10713,P22695 2 +FAD/NAD(P)-binding domain [IPR023753] 0.4094100055669736 0.330679687073574 0.7408864472777863 1.0 0.778939758966762 5 P00390,O95831 2 +Zinc finger, CCHC-type [IPR001878] 0.4115239906411832 0.3194843259367252 0.7493592752142031 1.0 0.7872351328261185 7 Q9NUD5,Q9BWF3 2 +Ubiquitin-conjugating enzyme E2 [IPR000608] 0.4092931836433575 0.29388302002359 0.768847293532603 1.0 0.8061410116899856 9 Q9C0C9,P68036,P60604 3 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.3897904986721827 0.2917857311176837 0.7704504556584386 1.0 0.806921039152173 2 O00154 1 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.3956669688967146 0.291737741070292 0.7704871506338291 1.0 0.806921039152173 4 Q9NRF9 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.8118660096776367 3 P61289,Q06323 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.8118660096776367 3 P61289,Q06323 2 +Histone-binding protein RBBP4, N-terminal [IPR022052] 0.3902007083825327 0.2829966909929236 0.7771793735730239 1.0 0.8123553839049558 3 Q09028,Q9BQ67 2 +Gelsolin-like domain [IPR007123] 0.3931406876516926 0.2732494451444667 0.7846614738809641 1.0 0.8192253873363079 5 O95486 1 +R3H domain [IPR001374] 0.3866587957497025 0.2710702197985814 0.7863370255147417 1.0 0.8206576450138402 3 O95453,Q9H6S0 2 +Rab-GTPase-TBC domain [IPR000195] 0.3905246116894547 0.2643980147763102 0.791473241095497 1.0 0.8250619974691484 5 O60343,Q9Y3P9 2 +Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099] 0.3842975206611587 0.263231381682151 0.7923722443719807 1.0 0.8256806032753922 3 Q14558,P11908 2 +EH domain [IPR000261] 0.3808498700749177 0.2233171761901332 0.8232886601257423 1.0 0.8539447062033612 6 P42566,Q9H223,Q9H4M9 3 +G-patch domain [IPR000467] 0.4013762242480393 0.2191196008264488 0.8265568825163183 1.0 0.8570056395084774 15 Q92917,Q8N1G2 2 +Homeobox domain [IPR001356] 0.3667133119129012 0.1891694382105096 0.8499600199487118 1.0 0.8770476790844606 5 Q96G23 1 +Clp ATPase, C-terminal [IPR019489] 0.3514311006196497 0.1733584683606604 0.8623696682212652 1.0 0.8876658451557556 2 Q9H078 1 +Metallo-beta-lactamase [IPR001279] 0.3575435488633095 0.1719138137425614 0.8635052864740815 1.0 0.8881580830045559 4 Q9UKF6,Q9NV88,Q5TA45 3 +EF-hand domain [IPR002048] 0.4154760461044348 0.1647980143183803 0.8691029670176698 1.0 0.8928958999550356 47 P80303,P60660,Q9H4M9,Q9Y680,O43852,Q14257,Q9H223,P14649,P17655,Q9BRK5,O75071,P07384 12 +NOSIC [IPR012976] 0.3491735537190044 0.1580721598701921 0.8743999379810459 1.0 0.8973143305829039 3 Q9Y2X3,Q8WWY3 2 +Nop domain [IPR002687] 0.3491735537190044 0.1580721598701921 0.8743999379810459 1.0 0.8973143305829039 3 Q9Y2X3,Q8WWY3 2 +Glutamine amidotransferase [IPR017926] 0.348686152937712 0.1478484145300924 0.8824623998977299 1.0 0.905244268991521 4 P27708,P17812,Q9NRF8 3 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.3413986426674515 0.1467998533290995 0.883290000456469 1.0 0.9054057591932396 2 Q9H993 1 +Transcription elongation factor S-II, central domain [IPR003618] 0.3423848878394395 0.1403929756673826 0.8883495074941021 1.0 0.9092122610791908 3 P23193,Q9BTC0 2 +Pleckstrin homology domain [IPR001849] 0.3881078365441616 0.1137387419115828 0.9094449001801104 1.0 0.9259637470700158 25 O60333,P31751,P31749,Q9UQ16 4 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.3482658403947912 0.0986082340415447 0.9214493320683668 1.0 0.93740816839184 10 Q9Y680 1 +DnaJ domain [IPR001623] 0.3592574675687746 0.084397857816252 0.9327401104262768 1.0 0.9467557394334336 16 Q99543,O60884,Q8IXB1 3 +Forkhead-associated (FHA) domain [IPR000253] 0.3372209837661696 0.0654907070904053 0.9477833051205198 1.0 0.9595018697773114 11 Q5SW79,O60934 2 +von Willebrand factor, type A [IPR002035] 0.315898345153677 0.0499159100808083 0.9601893986971256 1.0 0.9716972866215856 7 Q9NU22,P55036,P13010,Q99829,A3KMH1,O75131 6 +W2 domain [IPR003307] 0.3127365702435029 0.0440749810288295 0.9648446356460394 1.0 0.97604275758727 7 P55010 1 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.2971245180355668 0.0317113126566583 0.974702273229501 1.0 0.9852770453670452 5 Q9NX24 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.289259097704569 0.0200132745399511 0.9840327831352216 1.0 0.9939650766472408 5 P23634 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.289259097704569 0.0200132745399511 0.9840327831352216 1.0 0.9939650766472408 5 P23634 1 +B-box, C-terminal [IPR003649] 0.282433131881774 0.0174517808263163 0.9860762003066268 1.0 0.995656910772984 4 O15164 1 +Tudor domain [IPR002999] 0.2904728738303118 0.0023693983107175 0.9981094954383836 1.0 1.0 8 Q9Y2W6 1 +E3 ligase, CCCH-type zinc finger [IPR041367] 0.2629870129870194 0.0014108082732101 0.9988743382339684 1.0 1.0 3 Q9UPT8,Q86VM9 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9c08b734d0f1e58a7619da7969edf2b50e7e94e2 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "10TM putative phosphate transporter, cytosolic domain [IPR027815]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM, cysteine-rich domain [IPR006586]", "ADAMTS, cysteine-rich domain 2 [IPR041645]", "ADAMTS/ADAMTS-like, Spacer 1 [IPR010294]", "ADAMTS/ADAMTS-like, cysteine-rich domain 3 [IPR045371]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, F1 complex, delta/epsilon subunit, N-terminal [IPR020546]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AVL9/DENND6 domain [IPR018307]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Activin types I and II receptor domain [IPR000472]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apolipoprotein B100 C-terminal [IPR022176]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BMP-2-inducible protein kinase, C-terminal [IPR028182]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CCZ1/INTU, second Longin domain [IPR043988]", "CCZ1/INTU/HPS4, third Longin domain [IPR043989]", "CCZ1/INTU/HSP4, first Longin domain [IPR043987]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CUT domain [IPR003350]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain [IPR032880]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium-dependent channel, 7TM region, putative phosphate [IPR003864]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper type II ascorbate-dependent monooxygenase, C-terminal [IPR024548]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal [IPR000323]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D domain of beta-TrCP [IPR021977]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAPK3, catalytic domain [IPR042870]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1907 [IPR015021]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3528, homeobox protein, eukaryotic [IPR021918]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4371 [IPR025398]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin receptor-binding domain [IPR001799]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Ephrin-B ectodomain [IPR034255]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FAM83, N-terminal [IPR012461]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FNBP1L, F-BAR domain [IPR035494]", "FNBP1L, SH3 domain [IPR035493]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GS domain [IPR003605]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAT, C-terminal dimerisation domain [IPR008906]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homeobox domain, metazoa [IPR020479]", "Homeobox protein Hox1A3 N-terminal [IPR022067]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KOW [IPR005824]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LKB1 serine/threonine kinase interacting protein 1, N-terminal [IPR031782]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipid transport, open beta-sheet [IPR009454]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Little elongation complex subunit 2 , C-terminal [IPR019535]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MID domain of medPIWI [IPR041285]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIR motif [IPR016093]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex subunit Med13, C-terminal [IPR009401]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MnmG, N-terminal domain [IPR040131]", "MoaB/Mog domain [IPR001453]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nas2, N-terminal [IPR040815]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neogenin, C-terminal [IPR010560]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Nocturnin, deadenylase domain [IPR034965]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RING1 , RING finger, HC subclass [IPR042741]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II elongation factor ELL, N-terminal [IPR019464]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raf-like Ras-binding [IPR003116]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD5, SET domain [IPR044422]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Siah interacting protein, N-terminal [IPR015120]", "Sialate O-acetylesterase domain [IPR005181]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Somatomedin B domain [IPR001212]", "Somatomedin B, chordata [IPR020436]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor Elf, N-terminal [IPR022084]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Usher syndrome type-1C protein-binding protein 1, PDZ domain [IPR019536]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 36, GLUE domain [IPR021648]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vitellinogen, open beta-sheet [IPR015255]", "Vitellogenin, N-terminal [IPR001747]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat protein mio, zinc-ribbon like domain [IPR031488]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZNRF4 /RNF13/RNF167, PA domain [IPR044744]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "srGAP1/2/3, SH3 domain [IPR035648]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal [IPR026904]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APLP2", "APMAP", "APOB", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL8A", "ARL8B", "ARMC9", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5D", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCKDHA", "BCKDK", "BCOR", "BCS1L", "BET1", "BIRC6", "BLVRA", "BMS1", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C11orf54", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCNK", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNPY2", "COASY", "COG4", "COIL", "COLEC12", "COMMD7", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "DAGLB", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCTN1", "DCUN1D1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERI1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM192A", "FAM208A", "FAM3C", "FAM49B", "FAM83D", "FANCA", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCN1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR180", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPK1", "IVD", "IWS1", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8B", "LRRC8C", "LRSAM1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K2", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MBNL1", "MCAM", "MCC", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MEPCE", "METAP1", "METAP2", "METTL13", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGME1", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MRC2", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCEH1", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OCIAD1", "OCRL", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDXK", "PDZD11", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP2", "PYCR1", "PYCR2", "Q6ZSR9", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAI1", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RING1", "RIOK2", "RMND1", "RMND5A", "RNASEH2A", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRP12", "RSF1", "RTCA", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIAE", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK11IP", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TACC3", "TAF15", "TAGLN2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM63A", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS18", "VPS29", "VPS36", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WIZ", "WNK1", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YIPF4", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["AARS", "ACOT7", "ACTN1", "AFDN", "AIFM1", "AKT1", "AKT2", "ANK3", "AP1B1", "APP", "ARAF", "ARMC9", "ARMT1", "ATP11C", "ATP13A2", "ATP2B4", "ATP7A", "ATP7B", "B4GALT3", "BRAP", "BROX", "BUD23", "CAD", "CADM1", "CALU", "CAPN1", "CAPN2", "CD2BP2", "CD47", "CEP170", "CERS2", "CLASP1", "CLCN3", "CLCN6", "CLCN7", "CLPB", "CMTR1", "COLEC12", "COPG2", "CPNE1", "CPNE3", "CPSF3", "CTPS1", "CTPS2", "CTSB", "CUL4A", "CUL4B", "CXADR", "CYFIP1", "DEGS1", "DIAPH1", "DIAPH2", "DIDO1", "DNAJA2", "DNAJC10", "DNAJC2", "DNM3", "DRG2", "DSC3", "DSG2", "DTNA", "EFCAB14", "EHD1", "EHD4", "EHMT1", "EIF2B3", "EIF2D", "EIF5", "ELOA", "EP400", "EPHA7", "EPRS", "EPS15", "ERAP1", "ERAP2", "ERGIC3", "ETFDH", "EXOSC1", "EXT2", "EZR", "F11R", "FKBP7", "FNBP1L", "FUCA1", "GALNS", "GALNT1", "GALNT7", "GID8", "GINS3", "GLRX3", "GM2A", "GPKOW", "GRWD1", "GSR", "HDAC1", "HDGF", "HDGFL2", "HEXA", "HLA-B", "HLA-C", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "HSP90AA1", "HSP90AB1", "IDE", "IGF1R", "IGF2R", "IMPDH2", "INTS11", "INTS9", "IPO5", "IPO7", "ITGA6", "KDM3B", "KHSRP", "KIF1B", "LGALS3BP", "LNPEP", "LRP1", "LRP2", "LRSAM1", "MAEA", "MAN2B1", "MANBA", "MARC2", "MARS", "MCAM", "MCTS1", "MDN1", "MECR", "MFGE8", "MFN2", "MFSD10", "MPP2", "MPP5", "MRC2", "MRPL45", "MSH3", "MSH6", "MTA1", "MYL6", "MYL6B", "NAE1", "NBN", "NDUFS8", "NECAP2", "NEDD4", "NEO1", "NF1", "NHLRC2", "NHP2", "NIP7", "NIPSNAP1", "NLE1", "NLN", "NME6", "NOB1", "NOP58", "NSD2", "NSUN2", "NSUN5", "NUCB2", "NUDCD3", "P4HA1", "P4HA2", "PAFAH1B2", "PARN", "PDLIM5", "PFKM", "PFKP", "PM20D2", "PMPCA", "POLA1", "POLD1", "POLE3", "PRKCD", "PRPF3", "PRPF31", "PRPS2", "PRPSAP1", "PSMD4", "PSME1", "PSME3", "PTPRF", "RABGAP1", "RANBP9", "RAPGEF2", "RBBP4", "RBM4", "RCN2", "RNF20", "ROCK1", "ROCK2", "RP2", "RUFY3", "S100A13", "SDF4", "SDHB", "SEC16A", "SEC24A", "SEPHS1", "SKIV2L", "SLC3A2", "SLC4A7", "SNAP47", "SNX17", "SPPL2A", "SRP54", "STAG1", "STOM", "STX3", "STX5", "STX6", "STX7", "SV2A", "TBC1D4", "TBL1XR1", "TCEA1", "TDRKH", "TFRC", "THOP1", "TJP2", "TMEM97", "TMPO", "TOM1", "TOP3A", "TPBG", "TRAP1", "TRIM24", "TUBB2A", "TUBB6", "TUBG1", "U2SURP", "UBA6", "UBE2G2", "UBE2L3", "UBE2O", "UBE3C", "UBR5", "UQCRC2", "USP24", "USP5", "VWA8", "WARS", "XRCC5", "YBX1", "YTHDC2", "YWHAB", "YWHAE", "YWHAH", "ZADH2", "ZC3H18", "ZC3H4", "ZCCHC3"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fd09a3b6b2b39745d9faf596deccb20a9bd32593 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome B-type subunit [IPR023333]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..06dd2c276430628c524c8cf7c8ddbcae6ff113fd --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:032725a77150df2745241c481825fb2016091642d5e08597937553fec209855d +size 186109 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..fd09a3b6b2b39745d9faf596deccb20a9bd32593 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome B-type subunit [IPR023333]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3f536f24c0619d094d38b4a793d44c3ec5e9e9c1 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:240c7bee61f5ec8543ba5b11b7aae2101780973662155b08cc638f8515506917 +size 137400 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..56e7e0f98be562965af82d7328e3ceb21d366cb7 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4f2186897f4297ef7a49a22cbb0907dcf4b8dc08b2d4bbd8965a53bbbe977a7 +size 568498 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db8765ff2b96a28055b100a53623cf3bc524edce --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 3 6 2.48325259861364 0.0130188732853997 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0603501083335805 0.0385773062479974 0.0743799864466655 0.014977467250991 0.0003286021100258 +Syntaxin [IPR045242] 4 7 2.335041660609379 0.0195412444864651 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 1.0 1.0 1.0 0.0042425564235442 0.0003671727016274 +Proteasome B-type subunit [IPR023333] 6 7 2.1342527995170304 0.0328220927389082 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0676363609296167 1.0 0.0832836732680532 3.9104524570814734e-05 2.8311070051942505e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..63536d68b7083249063e34e0891c894777eb7e98 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 2600, + "title": "Average number of proteins per term", + "value": 1.2873076923076923 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ad187e9cfde0f136b91d908ac1dbc91ed987c73 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3c46adb4e29bd3a6e1d5e434a51831d9debe9f54 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,134 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein [IPR008155] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9997268467421376 0.0515133963185733 2 P05067 1 +Glycoside hydrolase, family 29 [IPR000933] 0.9864266745352608 2.917971256658083 0.0035231682474297 0.99989654894687 0.0515133963185733 2 P04066 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9864266745352608 2.917971256658083 0.0035231682474297 0.99989654894687 0.0515133963185733 2 P04066 1 +Palmitoyl protein thioesterase [IPR002472] 0.9846562407789898 2.910786068746985 0.0036052076969694 0.9999164844330112 0.0515133963185733 2 Q9UMR5 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9802243211334112 2.88985650263711 0.0038541771539086 0.9999563898854285 0.0515133963185733 3 Q9HB40,Q9H3G5 2 +Lysosome-associated membrane glycoprotein [IPR002000] 0.979049867217468 2.887991751559385 0.003877100394259 0.9999589226285728 0.0515133963185733 2 P13473 1 +Beta-hexosaminidase [IPR025705] 0.9772794334611968 2.880780499273083 0.0039669179765118 0.9999675074060128 0.0515133963185733 2 P06865 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9737308146399046 2.863278494795097 0.0041928185899309 0.9999819839235438 0.0515133963185733 3 Q8NBN3,Q9NPR9 2 +Tetraspanin/Peripherin [IPR018499] 0.961345529654761 2.8155958390688927 0.0048686872846679 0.999996916677096 0.0515133963185733 2 O60637 1 +Carbohydrate sulfotransferase 8-10 [IPR018011] 0.9578046621422216 2.8010407442855954 0.0050938087246266 0.9999982878293784 0.0515133963185733 2 Q8NCH0 1 +Sulfotransferase [IPR005331] 0.9580873671782744 2.798899811311701 0.0051277044922419 0.9999984329729592 0.0515133963185733 3 Q7LGA3,Q8NCH0 2 +CD36 family [IPR002159] 0.9492475656535804 2.7657607685099466 0.0056790179678092 0.9999996291739488 0.0515133963185733 2 Q14108 1 +Desmosomal cadherin [IPR009122] 0.945706698141039 2.7511184974004985 0.0059392154752901 0.999999812220828 0.0515133963185733 2 Q14574 1 +Nonaspanin (TM9SF) [IPR004240] 0.9456906729633996 2.7475288475338147 0.0060046226388694 0.9999998417483712 0.0515133963185733 3 Q99805,Q92544 2 +Beta-1,4-galactosyltransferase [IPR003859] 0.938920035408676 2.7229824322331795 0.0064695498035527 0.9999999531107272 0.0515133963185733 2 O60512 1 +P-type ATPase, subfamily IB [IPR027256] 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9999999992335068 0.0516692669288985 2 P35670 1 +Peptidase C2, calpain family [IPR022684] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9999999998169034 0.0516692669288985 2 P17655 1 +Exostosin-like [IPR004263] 0.9126586013573256 2.613214019669035 0.0089695114549768 0.9999999999329744 0.0516694094713659 2 Q93063 1 +Aminopeptidase N-type [IPR034016] 0.9096545615589108 2.5926826621178605 0.0095230595725133 0.9999999999843197 0.0516694094713659 4 Q9UIQ6,Q6P179,Q9NZ08 3 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9067571555030924 2.588350140946572 0.0096436898619223 0.9999999999885756 0.0518770192989541 2 O60830 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9035113602832644 2.574644058560498 0.0100343290443101 0.999999999995904 0.0521588821268782 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9035113602832644 2.574644058560498 0.0100343290443101 0.999999999995904 0.0521588821268782 2 Q93050 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.898435193386481 2.5448728597086787 0.010931753296318 0.9999999999996124 0.0533256258356976 4 Q9H0U9,Q99733,Q01105 3 +Integrin alpha chain [IPR000413] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.9999999999998348 0.0538369273673728 2 P23229 1 +Chloride channel, voltage gated [IPR001807] 0.8919716646989307 2.521248189040821 0.0116939339469988 0.9999999999999478 0.0542788059847354 3 P51797,P51790 2 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.8857290110049938 2.48325259861364 0.0130188732853997 0.9999999999999984 0.0557266805210261 6 Q9UIQ6,Q6P179,Q9NZ08 3 +Nucleobindin [IPR040250] 0.880790793744457 2.4780841875287347 0.0132089974072806 0.999999999999999 0.0557266805210261 2 P80303 1 +Prolyl 4-hydroxylase [IPR045054] 0.8772499262319238 2.462938325151771 0.0137803617904346 0.9999999999999998 0.0566913617960918 2 O15460 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8730171756676008 2.439963732221234 0.0146887365045584 1.0 0.0578647195634122 3 P28074 1 +SCAMP [IPR007273] 0.8548244319858392 2.3664017219739253 0.0179619424408217 1.0 0.0629510235162953 2 O15126 1 +Syntaxin [IPR045242] 0.8524900586568954 2.335041660609379 0.0195412444864651 1.0 0.0656424233395468 7 O43752,Q13277,O15400,Q13190 4 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.8436116848627789 2.317736282944104 0.0204636578498489 1.0 0.0670278658317174 2 Q9UBM7 1 +Zinc transporter Msc2-like [IPR045316] 0.8191206845677113 2.2105223591058833 0.0270689305088538 1.0 0.0771974335187967 2 Q8TAD4 1 +Cation efflux protein [IPR002524] 0.8191206845677113 2.2105223591058833 0.0270689305088538 1.0 0.0771974335187967 2 Q8TAD4 1 +Ras-related protein Ral [IPR028412] 0.8164650339333165 2.1988213546570754 0.027890627447918 1.0 0.0783175720887433 2 P11234 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8166395100256003 2.1937131521989595 0.0282560377114833 1.0 0.0786742365020628 3 Q9Y282 1 +Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081] 0.8143995278843361 2.1897104219831935 0.0285452447618708 1.0 0.0790390163800469 2 Q9BTT0 1 +Mpv17/PMP22 [IPR007248] 0.8111537326644886 2.1753753248724705 0.0296020020396838 1.0 0.0809308152504501 2 Q567V2 1 +Flotillin family [IPR027705] 0.8090882266155134 2.1662416068629864 0.0302927292527859 1.0 0.0820428083929618 2 O75955 1 +Peptidase M20 [IPR002933] 0.8067276482738276 2.155792249979711 0.0310998909163167 1.0 0.0831035111844023 2 Q8IYS1 1 +ER lumen protein retaining receptor [IPR000133] 0.8028917084685574 2.1387874760805117 0.0324528842142362 1.0 0.0855755567515356 2 O43731 1 +Proteasome B-type subunit [IPR023333] 0.8076241134751982 2.1342527995170304 0.0328220927389082 1.0 0.0861631067240123 7 P28070,P49721,P49720,P20618,P28074,P28072 6 +Ribonucleotide reductase small subunit [IPR033909] 0.8017114192977288 2.1335491302584386 0.032879705869266 1.0 0.0861631067240123 2 Q7LG56 1 +Ribonucleotide reductase small subunit family [IPR000358] 0.8017114192977288 2.1335491302584386 0.032879705869266 1.0 0.0861631067240123 2 Q7LG56 1 +Tropomyosin [IPR000533] 0.8027401479636511 2.131978037439098 0.0330086520971701 1.0 0.0862351520959014 3 P09493 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.7964001180289203 2.109941111480081 0.0348634285434488 1.0 0.0889744549643089 2 P54709 1 +H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415] 0.7913838890528202 2.08759155896952 0.0368346940813428 1.0 0.0912966678851205 2 Q9NX24 1 +Peptidase M3A/M3B [IPR045090] 0.7759740259740138 2.011975894918629 0.0442224780554134 1.0 0.1010922638984633 3 Q9BYT8,P52888 2 +Translation Initiation factor eIF- 4e [IPR001040] 0.7716140454411362 1.9990114997876371 0.045607109624919 1.0 0.1031117261085127 2 O60573 1 +P-type ATPase, subfamily IIB [IPR006408] 0.7710239008557143 1.9963552793482344 0.0458952649240824 1.0 0.103493225327506 2 P23634 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.7459427559752159 1.8828370672236316 0.0597224520026844 1.0 0.1232561135816692 2 Q13464 1 +Small GTPase, Ras-type [IPR020849] 0.7447075693026417 1.8631827390641416 0.0624365605185155 1.0 0.1274215520786031 4 P11234,P11233 2 +Coatomer gamma subunit [IPR017106] 0.7400413101209835 1.8559522920521156 0.0634603584665562 1.0 0.1288927371802736 2 Q9UBF2 1 +Nucleoside diphosphate kinase [IPR001564] 0.7390687253029664 1.8441856109907555 0.0651560946276488 1.0 0.1305129784529175 3 O75414 1 +ADP-ribosylation factor 1-5 [IPR045872] 0.7370905871938416 1.842485656021252 0.065404142769669 1.0 0.130808285539338 2 P84085 1 +Luc7-related [IPR004882] 0.7260920897284546 1.7845787622991032 0.0743296687826506 1.0 0.140977128463653 3 Q9Y383,Q9NQ29 2 +CTP synthase [IPR004468] 0.699026261434052 1.667391428386488 0.0954365971676423 1.0 0.1641105506850992 2 P17812 1 +THRAP3/BCLAF1 family [IPR029199] 0.6987311891413421 1.6660247029595558 0.095708494313909 1.0 0.1641438556834851 2 Q9Y2W1 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.6980519480519375 1.654787330441743 0.097967644857277 1.0 0.1666988721393457 3 O75915,O60831 2 +Dynamin [IPR022812] 0.6966083757128174 1.640355415165983 0.1009312897827439 1.0 0.1693040989904091 4 Q9UQ16 1 +Tubulin [IPR000217] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.1745356984556783 6 P23258,Q13885,Q9BUF5 3 +DNA mismatch repair MutS family [IPR045076] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.1864219731113702 3 P52701,P20585 2 +P-type ATPase [IPR001757] 0.6820134862686268 1.5346190563626263 0.1248774289329683 1.0 0.194653066682085 10 P35670,Q04656,Q9NQ11,Q8NB49 4 +Rab GDI protein [IPR000806] 0.6683387429920346 1.5245740589790655 0.1273653717790313 1.0 0.1968786959723432 2 P31150 1 +GDP dissociation inhibitor [IPR018203] 0.6683387429920346 1.5245740589790655 0.1273653717790313 1.0 0.1968786959723432 2 P31150 1 +AP complex subunit beta [IPR026739] 0.6664168072811129 1.5069240532196138 0.1318301252437246 1.0 0.201978977980957 3 Q10567 1 +Ezrin/radixin/moesin [IPR011174] 0.6519069355790504 1.438690337008073 0.1502382783386799 1.0 0.2209340488125296 3 P15311 1 +Graves disease carrier protein [IPR002167] 0.6485688993803435 1.43194087101989 0.15216074408879 1.0 0.2226324899442059 2 Q6KCM7 1 +Beta tubulin [IPR002453] 0.6535735380980442 1.4298436710501838 0.1527618919201394 1.0 0.2228884117545675 5 Q13885,P04350,P68371,Q9BUF5 4 +Proteasome, subunit alpha/beta [IPR001353] 0.6619972167372885 1.4205280533229394 0.1554540074372852 1.0 0.2254003292572067 14 P49721,P28074,P28072 3 +14-3-3 protein [IPR000308] 0.6515615639859479 1.4124563950241285 0.1578156212857457 1.0 0.2278293255652076 6 P31946,P62258,Q04917 3 +Tyrosine-tRNA ligase [IPR002307] 0.6417822366479817 1.4000525382247573 0.1614975862156538 1.0 0.2312190111017069 2 Q9Y2Z4 1 +Glycosyl transferase, family 35 [IPR000811] 0.6400118028917113 1.3917275581506592 0.1640049138925383 1.0 0.2330671800157454 2 P11216 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.6400118028917113 1.3917275581506592 0.1640049138925383 1.0 0.2330671800157454 2 P11216 1 +ClpA/B family [IPR001270] 0.6335202124520366 1.3611828398581818 0.1734559157112822 1.0 0.2418152176135838 2 Q9H078 1 +Importin beta family [IPR040122] 0.6284760108340741 1.310529689207774 0.190016707326396 1.0 0.2582558489538054 5 O00410,O60518,Q8TEX9 3 +KH domain-containing BBP-like [IPR045071] 0.6190112458795707 1.283348310712067 0.1993700742981135 1.0 0.2671970067912861 3 Q15637 1 +Ras GTPase-activating protein-binding protein [IPR039539] 0.6093242844496962 1.2471422216465102 0.2123453539315543 1.0 0.2784257367941565 2 Q9UN86 1 +RNA-binding protein 26/27 [IPR045137] 0.6078489229861379 1.240183263929988 0.2149076171850887 1.0 0.2803611664230963 2 Q9P2N5 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.6013573325464805 1.2095635326425718 0.2264464185054651 1.0 0.2900298956227631 2 Q9Y3C6 1 +Cullin [IPR045093] 0.6039269850572064 1.1848846972188567 0.2360630386224949 1.0 0.2982331877640849 6 Q13619,Q13620 2 +SNX17/27/31 [IPR037831] 0.582472705812932 1.12054571970899 0.262481281085593 1.0 0.3223671850838648 2 Q15036 1 +Mitofusin family [IPR027094] 0.5694895249336112 1.0594788803846895 0.2893817425831804 1.0 0.3443444076504663 2 O95140 1 +CPSF6/7 family [IPR034772] 0.568899380348193 1.0567071879891845 0.2906452434802913 1.0 0.3453736896932163 2 Q16630 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.5624077899085358 1.0262478021073675 0.3047747944696559 1.0 0.355502227734906 2 Q9NTI5 1 +DNA-directed DNA polymerase, family B [IPR006172] 0.5628689492325756 1.0181062245965071 0.3086274775383559 1.0 0.3582283221427346 3 P28340,P09884 2 +Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492] 0.5561957248722673 0.9867704490316151 0.3237551846528088 1.0 0.3701198046542581 3 Q9NX24 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.5663953606005666 0.9747640078246156 0.3296773343846975 1.0 0.3738164279983486 10 Q96BM9,Q9Y6B6 2 +Transmembrane protein 126 [IPR009801] 0.5479492475656591 0.9586440884711656 0.33773807398491 1.0 0.380962686490571 2 Q9H061 1 +NudC family [IPR037898] 0.5326054883446555 0.8873853220040536 0.3748714832060114 1.0 0.4103876440860472 2 Q8IVD9 1 +HnRNP R/Q splicing factor [IPR006535] 0.5302449100029551 0.8764777548643657 0.3807703644187779 1.0 0.4137078760922785 2 O43390 1 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.5221418941104098 0.828426647400144 0.4074289205663002 1.0 0.4313172611858227 3 Q96HS1 1 +Bicarbonate transporter, eukaryotic [IPR003020] 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.4462161238511163 2 Q9Y6M7 1 +Ubiquitin-activating enzyme E1 [IPR018075] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.448432092776638 2 A0AVT1 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.5092947772204303 0.7804950320848948 0.4350995505658637 1.0 0.4504704620571895 2 O95478 1 +Ubiquitin/SUMO-activating enzyme E1 [IPR000011] 0.5103305785123946 0.7743698827190693 0.4387120885153219 1.0 0.4531789551608411 3 A0AVT1,Q9UBE0 2 +Ribosomal protein L25/L23 [IPR013025] 0.5066391265860163 0.7684502564607987 0.4422197326423567 1.0 0.4566208518149831 2 P62750 1 +Actin-related protein 2/3 complex subunit 1 [IPR017383] 0.4986721746828009 0.7325098298208093 0.4638574451889878 1.0 0.4776353891054924 2 Q92747 1 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.4963115963411121 0.7219203630996343 0.4703434409166638 1.0 0.4837392984111257 2 Q13330 1 +ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.4871418745658821 3 P08237,Q01813 2 +ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.4871418745658821 3 P08237,Q01813 2 +ATP-dependent 6-phosphofructokinase [IPR022953] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.4871418745658821 3 P08237,Q01813 2 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.4930658011212873 0.7074072686089102 0.4793134212081398 1.0 0.4921859775439035 2 P36404 1 +Histone deacetylase [IPR003084] 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.4951588871043139 2 Q13547 1 +Histone deacetylase family [IPR000286] 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.4951588871043139 2 Q13547 1 +Alanine-tRNA ligase, class IIc [IPR002318] 0.4892298613160342 0.6903294138807042 0.4899870545887217 1.0 0.5023526584900143 2 P49588 1 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.4892298613160342 0.6903294138807042 0.4899870545887217 1.0 0.5023526584900143 2 P49588 1 +Aldo-keto reductase [IPR020471] 0.4791974033638324 0.6460738908538882 0.5182315032712097 1.0 0.5308912169051005 2 P14550 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.4786072587784054 0.6434902875601908 0.5199060149096097 1.0 0.5323968644210261 2 P12268 1 +Dynein light chain, type 1/2 [IPR001372] 0.4762466804367167 0.6331789606256825 0.5266167833734925 1.0 0.5388444064427708 2 Q96FJ2 1 +Ribosomal protein L3 [IPR000597] 0.4668043670699419 0.5923226654511534 0.5536345411397807 1.0 0.5660439665605308 2 P39023 1 +ThiF/MoeB/HesA family [IPR045886] 0.4787823710278919 0.5838760288313214 0.5593037218440409 1.0 0.5711664087959569 8 Q13564 1 +Cohesin subunit Scc3/SA [IPR039662] 0.4591324874594386 0.5596227391599229 0.5757367913174833 1.0 0.5877171799864376 2 Q8WVM7 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.4547064030687548 0.5409771307590003 0.5885233457389152 1.0 0.6000630191847763 2 P55039 1 +Major facilitator superfamily [IPR011701] 0.4628683002218449 0.5332940815440047 0.5938300239610754 1.0 0.6052364023123465 6 Q7L0J3,Q14728 2 +Adenylate kinase 3/4, mitochondrial [IPR028586] 0.4499852463853669 0.5212771423068495 0.6021737217872734 1.0 0.613019450527373 2 Q9UIJ7 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.4496901740926691 0.5200525842847628 0.6030269251359694 1.0 0.6136477516060747 2 Q15477 1 +Heat shock protein Hsp90 family [IPR001404] 0.4511366991437895 0.5044929690522713 0.6139150017144583 1.0 0.6244831785827824 4 P08238,Q12931,P07900 3 +G-protein alpha subunit, group I [IPR001408] 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 0.656278931479214 2 P08754 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.4356552538370762 0.4519489485174134 0.6513057605484118 1.0 0.6609660333434312 3 Q9HCS7,Q9BZJ0 2 +Monothiol glutaredoxin-related [IPR004480] 0.4269696075538661 0.4283677027560882 0.6683834348786704 1.0 0.6777679136835191 2 O76003 1 +Basigin-like [IPR043204] 0.4216583062850362 0.4077494639858219 0.6834576187296526 1.0 0.6925135653535062 2 P35613 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.4203069657615119 0.3918815831840747 0.6951457113347601 1.0 0.7038079631893989 3 Q08J23,Q96P11 2 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.4104455591619919 0.3653644100300396 0.7148394042755071 1.0 0.7226214817715079 2 O95319 1 +TAF15/EWS/TLS family [IPR034870] 0.412337662337666 0.3618323329901504 0.7174773286940939 1.0 0.7250062396442457 3 Q01844,P35637 2 +Proteasome activator PA28 [IPR009077] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.7824294090823097 3 P61289,Q06323 2 +Ribose-phosphate pyrophosphokinase [IPR005946] 0.3842975206611587 0.263231381682151 0.7923722443719807 1.0 0.7982052829783611 3 Q14558,P11908 2 +Profilin [IPR005455] 0.3502508114488002 0.1701337181734154 0.8649049767887156 1.0 0.868915355351878 2 P35080 1 +Profilin1/2/3, vertebrate [IPR005454] 0.3502508114488002 0.1701337181734154 0.8649049767887156 1.0 0.868915355351878 2 P35080 1 +Cyclin [IPR039361] 0.3363824136913529 0.1342543808352893 0.8932014254025513 1.0 0.8959582199253987 2 P14635 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.337271116361498 0.1106929028382559 0.9118598741082032 1.0 0.9139690334160868 5 Q14344,P04899,P29992,P08754 4 +UDPGP family [IPR002618] 0.317497786957801 0.091517892715297 0.927081089565446 1.0 0.9277947778561044 2 Q16222 1 +Small GTPase Rho [IPR003578] 0.2950796685248739 0.0216435286400698 0.9827323108200824 1.0 0.9831104302163196 6 P63000,P60953,P61586 3 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..994bd82fdb0824cc11185bf8d103b20377671025 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome non-ATPase regulatory subunit 9 [IPR035269]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADAMTS/ADAMTS-like [IPR013273]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, delta/epsilon subunit [IPR001469]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase PAAT-like [IPR028043]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "Acetate-CoA ligase [IPR011904]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl carrier protein (ACP) [IPR003231]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1/2/3 [IPR045068]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "C2H2-type Zinc finger protein, YY1-like [IPR017114]", "CAAX prenyl protease 1 [IPR027057]", "CCDC85 family [IPR019359]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CSC1-like protein 1 [IPR026957]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium permeable stress-gated cation channel 1-like [IPR045122]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cancer susceptibility candidate 4 [IPR026141]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle control protein 50A [IPR030351]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Cellular repressor of E1A-stimulated genes (CREG) [IPR014631]", "Centrin 2 [IPR037629]", "Centromere protein O [IPR018464]", "Centromere protein P [IPR027801]", "Centrosomal protein of 135kDa [IPR026732]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-6 [IPR002248]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Chromosome transmission fidelity protein 8 [IPR018607]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 167 [IPR028194]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 28 [IPR025271]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 2-associated protein 1/2 [IPR017266]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic dynein 2 light intermediate chain 1 [IPR040045]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENND6 [IPR024224]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Death-inducer obliterator 1 [IPR033082]", "Decaprenyl diphosphate synthase-like [IPR001441]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrodolichyl diphosphate synthase complex subunit Nus1 [IPR038887]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dim1 family [IPR004123]", "Dimethylallyltransferase [IPR039657]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Disks large 1-like [IPR016313]", "Distrobrevin [IPR017432]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RNF25 [IPR039133]", "E3 ubiquitin-protein ligase Rad18 [IPR039577]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [IPR029890]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin [IPR031328]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Essential MCU regulator, mitochondrial [IPR018782]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1-like [IPR030116]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein, ribosome biogenesis [IPR019991]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "GTPase, MTG1 [IPR016478]", "Galactokinase [IPR000705]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-glutamyltranspeptidase [IPR000101]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase family 29 [IPR001675]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "IPP transferase [IPR018022]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KRR1 interacting protein 1 [IPR018034]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL-like protein [IPR028563]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MIOS/Sea4 [IPR037593]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macoilin [IPR019130]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med20 [IPR013921]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type C family [IPR032037]", "Methylmalonic aciduria and homocystinuria type D protein [IPR019362]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase kinase [IPR021160]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis MoaE [IPR003448]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Molybdopterin synthase catalytic subunit, eukaryotes [IPR028888]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylgalactosamine-6-sulfatase [IPR035626]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Neogenin [IPR033024]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nocturnin [IPR040109]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Not2/Not3/Not5 [IPR040168]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 6 [IPR037994]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PNN-interacting serine/arginine-rich protein [IPR031937]", "PP2B [IPR043360]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic antigen Ma1 [IPR026528]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M12B, ADAM-TS1 [IPR013274]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase [IPR000720]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phorbol-12-myristate-13-acetate-induced protein 1 [IPR024140]", "Phosducin-like [IPR045037]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Platelet-activating factor acetylhydrolase, eucaryote [IPR016715]", "Platelet-activating factor acetylhydrolase-like [IPR005065]", "Plectin [IPR030269]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline racemase family [IPR008794]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein BRICK1 [IPR033378]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein FAM3C [IPR039219]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PAXX [IPR027873]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1356, TMEM106 [IPR009790]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF5565 [IPR041211]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Queuosine salvage protein family [IPR019438]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II elongation factor ELL [IPR031184]", "RNA polymerase II subunit A [IPR006811]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab11-family interacting protein class I [IPR037789]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Refilin family [IPR028215]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA small subunit methyltransferase H [IPR002903]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SLIT-ROBO Rho GTPase-activating protein 2 [IPR030252]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Ser/Thr protein kinase, TGFB receptor [IPR000333]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase Bud32 [IPR022495]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialate O-acetylesterase [IPR039329]", "Sialidase family [IPR026856]", "Sialyltransferase [IPR012163]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Snf8/Vps36 family [IPR040608]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Syndetin [IPR040047]", "Synergin gamma [IPR039656]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TEL2-interacting protein 1 [IPR016441]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Target of Myb protein 1 [IPR014645]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin [IPR005746]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumor necrosis factor alpha-induced protein 8-like [IPR008477]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0687 [IPR026794]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "Usher syndrome type-1C protein-binding protein 1-like [IPR040171]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar fusion protein Ccz1 [IPR013176]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting protein 36 [IPR037855]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA splicing factor Cwf18-like [IPR013169]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA isopentenyltransferase, eukaryotes [IPR030666]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [IPR004416]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related [IPR002218]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSS1", "ACTL6A", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANKS1A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARHGAP35", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCLAF1", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOLA3", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C10orf88", "C12orf29", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX3", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC138", "CCDC167", "CCDC22", "CCDC28A", "CCDC47", "CCDC6", "CCDC85C", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK2AP1", "CDK5RAP1", "CDK5RAP3", "CDKAL1", "CEBPZ", "CELF2", "CENPB", "CENPO", "CENPP", "CEP135", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST12", "CHST14", "CHTF8", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG3", "COG6", "COG7", "COG8", "COIL", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENND6A", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFNB1", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNTB", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GALNS", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM2", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRIPAP1", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "JAGN1", "JUP", "KARS", "KCTD10", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L3HYPDH", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LLPH", "LMF2", "LNPEP", "LONP1", "LONP2", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZIC", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAP1B", "MAP1S", "MAP4", "MAP4K5", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCC", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL15", "METTL16", "METTL3", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGST3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MLEC", "MMAB", "MMACHC", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2AS2", "NCDN", "NCEH1", "NCKAP1", "NCLN", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA13", "NDUFA4", "NDUFAB1", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFCD", "NELFE", "NEO1", "NES", "NEU1", "NF1", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRDE2", "NRM", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUS1", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH2", "PAIP2", "PAK2", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAXX", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RFC1", "RFLNB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RMND5A", "RNASEH2A", "RNASET2", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMG1", "SMG5", "SMG8", "SMIM12", "SMPD4", "SMS", "SMU1", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPNS1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRGAP2", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNRG", "TAB1", "TACC3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TECR", "TEDC1", "TEFM", "TERF2", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM206", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM63A", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNFAIP8", "TNKS1BP1", "TNPO1", "TOE1", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53RK", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC27", "TTC37", "TTC38", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC9", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBR4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR41", "WDR46", "WDR74", "WDR82", "WDR91", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H14", "ZC3H4", "ZCCHC3", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10"], "leading_proteins": ["AARS", "AK3", "AKR1A1", "ANP32E", "AP1B1", "APP", "ARF5", "ARL2", "ARL6IP5", "ARL8A", "ARPC1A", "ATP11C", "ATP13A2", "ATP1B3", "ATP2B4", "ATP6V0A1", "ATP7A", "ATP7B", "B4GALT3", "BSG", "CAPN2", "CCNB1", "CDC42", "CELF2", "CHST14", "CLCN3", "CLCN6", "CLPB", "COPG2", "CPSF6", "CPVL", "CRNKL1", "CTPS1", "CUL4A", "CUL4B", "DHCR7", "DNM3", "DRG2", "DSC3", "DYNLL2", "EIF4E2", "ERAP1", "ERAP2", "ERGIC3", "EWSR1", "EXT2", "EZR", "FLOT1", "FUCA1", "FUS", "G3BP2", "GDI1", "GLRX3", "GNA11", "GNA13", "GNAI2", "GNAI3", "GPR108", "HDAC1", "HEXA", "HNRNPR", "HS2ST1", "HSP90AA1", "HSP90AB1", "IMPDH2", "IPO4", "IPO5", "ITGA6", "KDELR3", "LAMP2", "LNPEP", "LUC7L", "LUC7L2", "MFN2", "MFSD10", "MPV17L2", "MSH3", "MSH6", "MTA1", "NAE1", "NAP1L4", "NHP2", "NLN", "NME6", "NSA2", "NSUN2", "NSUN5", "NUCB2", "NUDCD3", "P4HA2", "PDS5B", "PFKM", "PFKP", "PFN2", "PGAM5", "PM20D2", "POLA1", "POLD1", "PPIL1", "PPT2", "PRAF2", "PRPS2", "PRPSAP1", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", 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100644 index 0000000000000000000000000000000000000000..c2caa497f59bff05859443ccfebfdeb454a1fe8d --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df7f10faf8704d584486f448dd6f41a95410239f44172d70c08e0b4fd84d1374 +size 226552 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d9df3e811e5c631922b583bd2b06cdabec067465 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,11 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycoside hydrolase superfamily [IPR017853] 12 18 2.6053910263122884 0.0091769460681749 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 1.2615545167208563e-11 1.4061110647098428e-07 1.3147474012485992e-12 5.990103716077028e-15 4.150575773415949e-11 +Glycosyl hydrolase, all-beta [IPR013780] 6 9 2.502668593756258 0.0123260903074773 3.628640776699029 7.919902912621359 0.108448733903935 0.2677010542317815 1.6191976609214136 0.9906808437954988 1.5895506376095985 0.2857304479214345 2.2636308823174428e-06 3.066034551708988e-05 5.369271916582234e-06 2.899795571966189e-07 8.104989222609044e-07 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 3 6 2.48325259861364 0.0130188732853997 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0676363609296167 0.0432957136582515 0.0832836732680532 0.0189506401306209 0.0005688349419973 +Peptidase M4/M1, CTD superfamily [IPR027268] 3 6 2.48325259861364 0.0130188732853997 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0676363609296167 0.0432957136582515 0.0832836732680532 0.0189506401306209 0.0005688349419973 +Galactose mutarotase-like domain superfamily [IPR011013] 2 5 2.4552274717460087 0.0140795464426597 1.6213592233009708 4.237864077669903 -0.1710088816529627 0.4259251030719748 1.156379559873228 0.9330622415325056 1.182861393037172 0.315870474383572 0.0603501083335805 1.0 0.0743799864466655 0.014977467250991 0.0053031795330487 +Metallopeptidase, catalytic domain superfamily [IPR024079] 2 5 2.3524888122141268 0.0186482507415242 1.4587378640776698 4.228155339805825 1.1164526094555864 0.2711201472648778 0.9505983599630128 0.5714769615803577 0.9352765369569976 0.2609195154950394 0.0074762930075664 0.0802348466038066 0.0113213926532688 0.0075105395483816 0.0465653262864464 +SNARE [IPR010989] 4 7 2.16455476565614 0.0304217982834635 2.4854368932038833 5.364077669902913 0.7966086592831925 0.3585374753437345 1.5079985943563208 1.7302199405020957 1.098385457365192 0.3157194502762394 1.0 1.0 1.0 0.0062969264366488 0.0007388687073799 +Fibronectin type III superfamily [IPR036116] 3 7 2.130791912907537 0.0331062888974305 2.2257281553398056 5.589805825242719 -0.3209057323720775 0.5133796044193292 1.3812257831232946 2.0501463270450144 0.914078257814304 0.3019356379166223 0.425452185951316 0.295480255529908 0.497470817800254 0.5185914106235352 0.4545916116320574 +Galactose-binding-like domain superfamily [IPR008979] 5 9 2.1108890201155988 0.0347818520603377 3.0266990291262137 10.45388349514563 0.2272915730277323 0.4946686484554474 2.0113188873716883 2.8129916124420524 1.0072294248002038 0.3052099564304033 0.3281186291474333 0.2222355866483168 0.08610744549237 0.0014035458573663 0.0359869143678365 +Immunoglobulin-like domain superfamily [IPR036179] 8 15 2.036116462428891 0.0417386620312951 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 0.0596561254697165 0.433640456963297 0.0987427785556486 0.0019270486740707 0.0525675162058527 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..594d68a28d685e0ea6cca163b5bd93c98ff2e4d5 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 1016, + "title": "Average number of proteins per term", + "value": 4.84251968503937 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9d9b0ef4b3ed9266360de2a2635cc4ae5d41503d --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..90eea00686658aade5e76ed1d20b9d57381e08dd --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,156 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9594997910210632 0.0615414439441447 2 P05067 1 +E2 domain superfamily [IPR036176] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9594997910210632 0.0615414439441447 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9594997910210632 0.0615414439441447 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9949837710239008 2.9526119307308445 0.0031509781139551 0.9594997910210632 0.0615414439441447 2 P05067 1 +C-type lectin fold [IPR016187] 0.9852463853644136 2.913181824584142 0.0035776621955889 0.9737849753249608 0.0615414439441447 2 Q5KU26 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.9852463853644136 2.913181824584142 0.0035776621955889 0.9737849753249608 0.0615414439441447 2 Q5KU26 1 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.9822819741607688 2.89826082895226 0.0037523838359605 0.9780632673350218 0.0615414439441447 3 P34059 1 +LDL receptor-like superfamily [IPR036055] 0.9781399349451608 2.881334323420639 0.0039599535863206 0.9822487617084392 0.0615414439441447 3 P98164 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.9775678866587948 2.8789939317824302 0.0039894601038601 0.9827750825775472 0.0615414439441447 3 P06865,P54802 2 +Fibronectin type II domain superfamily [IPR036943] 0.9632885237538558 2.820359613326383 0.0047969857951211 0.99244438823064 0.0615414439441447 3 P11717 1 +Kringle-like fold [IPR013806] 0.9632885237538558 2.820359613326383 0.0047969857951211 0.99244438823064 0.0615414439441447 3 P11717 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.961345529654761 2.8155958390688927 0.0048686872846679 0.9929777191069864 0.0615414439441447 2 O60637 1 +Beta-Galactosidase/glucuronidase domain superfamily [IPR036156] 0.9501327825317176 2.769417336574836 0.005615665233053 0.9967255201269688 0.0615414439441447 2 O00462 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9991120912200148 0.0615414439441447 3 P10321,P01889 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9991120912200148 0.0615414439441447 3 P10321,P01889 2 +Ricin B-like lectins [IPR035992] 0.9288455860643652 2.673850694462045 0.0074985827944396 0.9995226535034872 0.0615414439441447 4 Q86SF2,Q10472,Q9UBG0 3 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.9997572033699722 0.0615414439441447 2 O00754 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.9997572033699722 0.0615414439441447 2 O00754 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.9997572033699722 0.0615414439441447 2 O00754 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.9203304809678312 2.6454287673210186 0.0081587462875902 0.9997572033699722 0.0615414439441447 2 O00754 1 +Calpain large subunit, domain III superfamily [IPR036213] 0.9161994688698668 2.628097555756389 0.0085863887379842 0.9998433410772036 0.0615414439441447 2 P17655 1 +Growth factor receptor cysteine-rich domain superfamily [IPR009030] 0.917921464422803 2.6277417838029 0.0085953733894481 0.999844776894956 0.0615414439441447 4 P98164,Q15375,Q07954 3 +Glycoside hydrolase superfamily [IPR017853] 0.9115146985843218 2.6053910263122884 0.0091769460681749 0.9999144853334786 0.0615414439441447 18 O00462,Q01459,P04066,P08195,P06280,P06865,P04062,P07686,P16278,Q9BTY2,P54802,P10253 12 +NAP-like superfamily [IPR037231] 0.898435193386481 2.5448728597086787 0.010931753296318 0.9999858785420456 0.0642003546188387 4 Q9H0U9,Q99733,Q01105 3 +Integrin alpha, N-terminal [IPR028994] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.999989880315436 0.0645492674210953 2 P23229 1 +Cadherin-like superfamily [IPR015919] 0.8937426210153407 2.528804101724171 0.0114451888686133 0.9999916676759412 0.0645492674210953 3 Q14126,Q14574 2 +Catenin binding domain superfamily [IPR027397] 0.8937426210153407 2.528804101724171 0.0114451888686133 0.9999916676759412 0.0645492674210953 3 Q14126,Q14574 2 +Chloride channel, core [IPR014743] 0.8919716646989307 2.521248189040821 0.0116939339469988 0.9999935475540684 0.0645492674210953 3 P51797,P51790 2 +Glycosyl hydrolase, all-beta [IPR013780] 0.8913608377086971 2.502668593756258 0.0123260903074773 0.9999966317917032 0.0648876049346993 9 P04066,P08195,P06280,O00754,Q9BTY2,P10253 6 +Integrin domain superfamily [IPR032695] 0.8866587957497039 2.4985408524139854 0.0124705768008797 0.999997097014298 0.0650227583885676 3 P06756,P23229 2 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.8857290110049938 2.48325259861364 0.0130188732853997 0.9999983488381838 0.065200582717052 6 Q9UIQ6,Q6P179,Q9NZ08 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.8857290110049938 2.48325259861364 0.0130188732853997 0.9999983488381838 0.065200582717052 6 Q9UIQ6,Q6P179,Q9NZ08 3 +Galactose mutarotase-like domain superfamily [IPR011013] 0.878476538937465 2.4552274717460087 0.0140795464426597 0.9999994462082902 0.068444110936566 5 O00754,P10253 2 +Peptidase S1, PA clan [IPR009003] 0.8740041310120992 2.4490314534334745 0.0143240938958097 0.9999995695853676 0.068647544330862 2 Q7KZN9 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8549072479226859 2.3524888122141268 0.0186482507415242 0.9999999950580748 0.0823766206669069 5 P42892,Q9UHI8 2 +Cation efflux transmembrane domain superfamily [IPR027469] 0.8191206845677113 2.2105223591058833 0.0270689305088538 0.9999999999992212 0.1052077425900169 2 Q8TAD4 1 +SNARE [IPR010989] 0.8143344381393741 2.1645547656561397 0.0304217982834635 0.9999999999999768 0.1149016619182119 7 O43752,Q13277,O15400,Q13190 4 +GINS, helical bundle-like domain superfamily [IPR036224] 0.805904530926056 2.1460681241157205 0.0318675439712294 0.9999999999999948 0.1183025069989316 3 Q9BRX5 1 +Ferritin-like superfamily [IPR009078] 0.8017114192977288 2.1335491302584386 0.032879705869266 0.9999999999999982 0.1207330274742636 2 Q7LG56 1 +Ribonucleotide reductase-like [IPR012348] 0.8017114192977288 2.1335491302584386 0.032879705869266 0.9999999999999982 0.1207330274742636 2 Q7LG56 1 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.8011212747122882 2.1309288812108953 0.0330950016316187 0.9999999999999986 0.1207330274742636 2 Q9BYT8 1 +Fibronectin type III superfamily [IPR036116] 0.806859033388942 2.130791912907537 0.0331062888974305 0.9999999999999986 0.1207330274742636 7 Q15375,Q92859,P08069 3 +Galactose-binding-like domain superfamily [IPR008979] 0.80385340433328 2.1108890201155988 0.0347818520603377 0.9999999999999998 0.1232349713318428 9 O00462,Q15375,P08236,P16278,Q08431 5 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.7964001180289203 2.109941111480081 0.0348634285434488 0.9999999999999998 0.1232349713318428 2 P54709 1 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.7836744839539049 2.040581029354223 0.0412924893932356 1.0 0.1341532295592826 4 Q8TD19,Q9P258 2 +Immunoglobulin-like domain superfamily [IPR036179] 0.7896658231008764 2.036116462428891 0.0417386620312951 1.0 0.1341532295592826 15 Q08722,Q9BY67,P10321,Q92859,P43121,P01889,P78310,Q9Y624 8 +SGNH hydrolase superfamily [IPR036514] 0.7805593574721823 2.026509692422783 0.0427125805049786 1.0 0.1360375604798065 4 Q9HAT2 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.7759740259740138 2.011975894918629 0.0442224780554134 1.0 0.1398222146079276 3 Q9BYT8,P52888 2 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.7716140454411362 1.9990114997876371 0.045607109624919 1.0 0.1427511093519365 2 O60573 1 +GYF-like domain superfamily [IPR035445] 0.7683682502213041 1.9843937503575368 0.0472119621909474 1.0 0.1438257332613301 2 O95400 1 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.7654175272941786 1.971086836214727 0.0487139441690513 1.0 0.1453415227168727 2 Q9C0B1 1 +BRO1 domain superfamily [IPR038499] 0.7651097313848506 1.9628557840233103 0.0496629337433749 1.0 0.1466788973350841 3 Q5VW32 1 +Dimeric alpha-beta barrel [IPR011008] 0.7456476836825057 1.8814943763729648 0.0599046995500214 1.0 0.1653890618011461 2 Q9BPW8 1 +Coatomer, gamma subunit, appendage domain superfamily [IPR037067] 0.7400413101209835 1.8559522920521156 0.0634603584665562 1.0 0.1676489725686041 2 Q9UBF2 1 +PWI domain superfamily [IPR036483] 0.7395895254859142 1.846571463706776 0.0648092731696867 1.0 0.1684046586711042 3 O43395 1 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.7378610192113669 1.831712696813559 0.0669942360113431 1.0 0.1721426637152721 4 P11717 1 +Nucleoside diphosphate kinase-like domain superfamily [IPR036850] 0.7371180449883759 1.8282924323630207 0.0675056749753713 1.0 0.1723260446607468 4 O75414 1 +HSP40/DnaJ peptide-binding [IPR008971] 0.7363958583851304 1.8183301380417844 0.069013689101316 1.0 0.1752947703173426 5 O60884 1 +Six-bladed beta-propeller, TolB-like [IPR011042] 0.7340029765459516 1.7910234574030477 0.0732895308084895 1.0 0.1817662483054029 8 P98164,Q07954 2 +RUN domain superfamily [IPR037213] 0.7123045146060774 1.728750154407007 0.0838538207321997 1.0 0.1936260951452611 2 Q7L099 1 +Immunoglobulin-like fold [IPR013783] 0.7120697680654575 1.7147548332628886 0.086390185656952 1.0 0.1985801552657539 34 Q08722,Q15375,P10321,Q8IZA0,Q9BY67,O00462,P08236,P43121,Q9Y624,P01889,P78310,Q92859,P04439 13 +RuvA domain 2-like [IPR010994] 0.6959858323494561 1.64517357862713 0.0999340205223635 1.0 0.2214750725107699 3 Q96QE5,Q7KZ85 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.2287483243836743 6 P23258,Q13885,Q9BUF5 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.2287483243836743 6 P23258,Q13885,Q9BUF5 3 +Tubulin, C-terminal [IPR023123] 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.2287483243836743 6 P23258,Q13885,Q9BUF5 3 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6876250958959106 1.5774851822730669 0.1146839289651726 1.0 0.2417403979846793 7 P23258,Q13885,Q9BUF5 3 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2428265701040412 3 P52701,P20585 2 +MutS, connector domain superfamily [IPR036678] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2428265701040412 3 P52701,P20585 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.2428265701040412 3 P52701,P20585 2 +P-type ATPase, A domain superfamily [IPR008250] 0.6820134862686268 1.5346190563626263 0.1248774289329683 1.0 0.2507420312171855 10 P35670,Q04656,Q9NQ11,Q8NB49 4 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.6820134862686268 1.5346190563626263 0.1248774289329683 1.0 0.2507420312171855 10 P35670,Q04656,Q9NQ11,Q8NB49 4 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.6820134862686268 1.5346190563626263 0.1248774289329683 1.0 0.2507420312171855 10 P35670,Q04656,Q9NQ11,Q8NB49 4 +Zinc finger, ZZ-type superfamily [IPR043145] 0.6686338152847257 1.5259533188103394 0.1270214905366007 1.0 0.2535438789492855 2 Q9Y4J8 1 +Beta-lactamase/transpeptidase-like [IPR012338] 0.6544703452345796 1.4596356851552166 0.1443902263330845 1.0 0.2701666113340955 2 P83111 1 +Moesin tail domain superfamily [IPR008954] 0.6519069355790504 1.438690337008073 0.1502382783386799 1.0 0.2780343804137641 3 P15311 1 +14-3-3 domain superfamily [IPR036815] 0.6515615639859479 1.4124563950241285 0.1578156212857457 1.0 0.2867272092401206 6 P31946,P62258,Q04917 3 +HIT-like superfamily [IPR036265] 0.6442125851200237 1.402423313687761 0.1607888755249784 1.0 0.2884860414225234 3 Q9BX68 1 +Heavy metal-associated domain superfamily [IPR036163] 0.6320154286338376 1.3448374476723737 0.1786777341622145 1.0 0.3056171345266161 3 P35670 1 +Histidine phosphatase superfamily [IPR029033] 0.6154393676050571 1.2399399313224857 0.2149976128524131 1.0 0.3478305328949869 6 P11117,Q96HS1 2 +Immunoglobulin E-set [IPR014756] 0.5960977884374384 1.1004718212282971 0.271126600674596 1.0 0.4039070766647941 13 P61916 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.5997592546788124 1.0852959403659446 0.2777906033509054 1.0 0.4096302656088823 23 Q16739,O60512,Q86SF2,Q93063,P15291,Q10472,Q10471 7 +Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223] 0.5718501032753109 1.070569650509598 0.2843629758408099 1.0 0.4139151625419239 2 O75695 1 +Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098] 0.5718501032753109 1.070569650509598 0.2843629758408099 1.0 0.4139151625419239 2 O75695 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.5833608500817653 1.0636095418601628 0.2875056180340545 1.0 0.4165483214311625 9 Q08380 1 +TFIIS/LEDGF domain superfamily [IPR035441] 0.5781967063385425 1.062030323608447 0.2882219192579796 1.0 0.4165483214311625 6 Q14241,Q7Z4V5 2 +DNA/RNA polymerase superfamily [IPR043502] 0.5743219755701722 1.0527328421566349 0.2924634520798244 1.0 0.4202869410369187 5 P54098,P09884,P28340 3 +Band 7/SPFH domain superfamily [IPR036013] 0.5752037330624021 1.0396036379947893 0.2985240860298641 1.0 0.4265829414997777 7 P27105 1 +DNA polymerase, palm domain superfamily [IPR023211] 0.5628689492325756 1.0181062245965071 0.3086274775383559 1.0 0.4385531708796778 3 P28340,P09884 2 +DNA polymerase family B, thumb domain [IPR042087] 0.5628689492325756 1.0181062245965071 0.3086274775383559 1.0 0.4385531708796778 3 P28340,P09884 2 +Cullin homology domain superfamily [IPR036317] 0.5527816902692853 0.9329121307021886 0.3508653385558637 1.0 0.4778541340117394 7 Q13619,Q13620 2 +Pyruvate kinase-like, insert domain superfamily [IPR011037] 0.5404368358913758 0.9131158985582832 0.3611815895477459 1.0 0.4834077474768355 3 P14618,Q969Z3 2 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.5595689683693926 0.891824958743149 0.3724867616232812 1.0 0.494055548053856 19 P49721,P28074,P28072,P28070 4 +Diaphanous, GTPase-binding domain superfamily [IPR044933] 0.5168240850058948 0.8040202832415461 0.4213852609770452 1.0 0.5318992659418653 3 O60879,O60610 2 +Phosphotransferase/anion transporter [IPR016152] 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.5368621969408648 2 Q9Y6M7 1 +Ubiquitin-activating enzyme E1, SCCH domain [IPR042063] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.5387999522572634 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.5387999522572634 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252] 0.5101799940985653 0.7845167293610228 0.4327369695294556 1.0 0.5387999522572634 2 A0AVT1 1 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.5103305785123943 0.7743698827190693 0.4387120885153219 1.0 0.5442386836771271 3 Q9UBT2,A0AVT1 2 +HECT, E3 ligase catalytic domain [IPR035983] 0.5115539194733625 0.7402748487371484 0.4591332389672713 1.0 0.5606723206619564 7 P46934,Q15386,O95071 3 +Phosphofructokinase superfamily [IPR035966] 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.5763173453619193 3 P08237,Q01813 2 +Ureohydrolase domain superfamily [IPR023696] 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.5846624928189681 2 Q13547 1 +Histone deacetylase domain superfamily [IPR037138] 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.5846624928189681 2 Q13547 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.5251394748663405 0.7008107440082146 0.4834211321358128 1.0 0.5847093693452212 25 P07858,Q8N6M0,Q9Y4E8,P17655,P53634,P07384 6 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.4892298613160342 0.6903294138807042 0.4899870545887217 1.0 0.5919463108943416 2 P49588 1 +SRP/SRP receptor, N-terminal [IPR036225] 0.4794924756565359 0.6473665464303371 0.5173947417960045 1.0 0.6191673235155956 2 P61011 1 +Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101] 0.4794924756565359 0.6473665464303371 0.5173947417960045 1.0 0.6191673235155956 2 P61011 1 +Dynein light chain superfamily [IPR037177] 0.4762466804367167 0.6331789606256825 0.5266167833734925 1.0 0.6287222701615375 2 Q96FJ2 1 +PH-like domain superfamily [IPR011993] 0.4870634476170254 0.6269740490738555 0.5306762461477545 1.0 0.6328251949367589 57 P21359,P31751,Q9UQ16,Q9NVZ3,P05067,P31749,Q06481,Q86X55 8 +Myosin S1 fragment, N-terminal [IPR008989] 0.4709182167109514 0.5884000027087617 0.5562638359349203 1.0 0.6617846104331138 4 P35580,Q7Z406,P35579 3 +Ubiquitin-activating enzyme [IPR035985] 0.4787823710278919 0.5838760288313214 0.5593037218440409 1.0 0.6646229022146731 8 Q13564 1 +RNA-binding S4 domain superfamily [IPR036986] 0.4619244391971662 0.5605069382529597 0.5751337084763928 1.0 0.680251278011659 3 Q9Y2Z4,P46781 2 +Adenylate kinase, active site lid domain superfamily [IPR036193] 0.4499852463853669 0.5212771423068495 0.6021737217872734 1.0 0.7016152538255387 2 Q9UIJ7 1 +HSP90, C-terminal domain [IPR037196] 0.4511366991437895 0.5044929690522713 0.6139150017144583 1.0 0.714476107379026 4 P08238,Q12931,P07900 3 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.4496604664895304 0.4983714528213748 0.6182222539285489 1.0 0.7186656864890225 4 Q16540,P62750,P61313 3 +Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035] 0.437297137798774 0.4693772097826031 0.6388000355400001 1.0 0.735017934437871 2 P07814 1 +Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056] 0.437297137798774 0.4693772097826031 0.6388000355400001 1.0 0.735017934437871 2 P07814 1 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4541374172172399 0.4369053392630096 0.6621799996180167 1.0 0.7567771424205905 13 Q15375,Q6UWE0 2 +Alpha/Beta hydrolase fold [IPR029058] 0.4624321917899189 0.4022973336462133 0.6874652167140978 1.0 0.7821552745593766 25 Q8NCC3,P10619,Q9HB40,P50897,Q9H3G5,Q9UMR5,P42785 7 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.4347859046765578 0.3819709446576798 0.7024829163314958 1.0 0.7912667882403546 10 Q13619,Q96MW5,Q13616,Q13620 4 +L27 domain superfamily [IPR036892] 0.4224679866748974 0.3795246290105851 0.7042983185855469 1.0 0.7923623039271888 5 Q14168 1 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.4116258483328407 0.3697497177834192 0.7115689834701673 1.0 0.7988442952549061 2 Q9UBT2 1 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.8134389293159271 4 O95486 1 +Gelsolin-like domain superfamily [IPR036180] 0.4116997267024505 0.3491575788018771 0.7269710116327379 1.0 0.8134389293159271 4 O95486 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4182205539433438 0.3443011179089323 0.7306198436590183 1.0 0.8166223995132702 7 Q10713,P22695 2 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.4014167650531312 0.3220465899303075 0.7474173994346529 1.0 0.8326492081421134 3 Q9Y490,P18206 2 +Rho GTPase activation protein [IPR008936] 0.4188993312504542 0.3207608414553591 0.7483916365411982 1.0 0.8328213611455174 10 P21359 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.8574274922405004 3 P61289,Q06323 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.8574274922405004 3 P61289,Q06323 2 +Proteasome activator superfamily [IPR036252] 0.3904958677685988 0.2839995554531266 0.7764107213201381 1.0 0.8574274922405004 3 P61289,Q06323 2 +Rhomboid-like superfamily [IPR035952] 0.3890200708382533 0.2789989961706225 0.7802455951305303 1.0 0.8597934106861375 3 Q12893,Q9BUN8 2 +R3H domain superfamily [IPR036867] 0.3866587957497025 0.2710702197985814 0.7863370255147417 1.0 0.8655670833401706 3 O95453,Q9H6S0 2 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.3905246116894547 0.2643980147763102 0.791473241095497 1.0 0.8666707596490117 5 O60343,Q9Y3P9 2 +MFS transporter superfamily [IPR036259] 0.3996181419864773 0.25972059065663 0.7950793084963694 1.0 0.8695377582694417 9 P41440,Q7L0J3,Q6NT16,Q14728 4 +Arp2/3 complex subunit 2/4 [IPR034666] 0.3697255827677737 0.2266426247605132 0.8207016448564906 1.0 0.8904444673579657 2 P59998 1 +Zinc-binding ribosomal protein [IPR011332] 0.3710153482880814 0.2208754708517436 0.8251893971664082 1.0 0.8938085581248089 3 P61513,P61927 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.4051275960142234 0.1989952166889202 0.8422664862990086 1.0 0.906507150508255 20 P58546,Q9H9B1,Q9P2R3,Q9ULT8,Q6W2J9,Q9ULH0,Q9H078 7 +NTF2-like domain superfamily [IPR032710] 0.374128207813594 0.1937878728888619 0.8463419830451833 1.0 0.9095574671494544 7 Q9BRJ2,P61970,Q13555,O43615 4 +Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866] 0.3575435488633095 0.1719138137425614 0.8635052864740815 1.0 0.9199491027119956 4 Q9UKF6,Q9NV88,Q5TA45 3 +Profilin superfamily [IPR036140] 0.3502508114488002 0.1701337181734154 0.8649049767887156 1.0 0.9201502161438064 2 P35080 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.3560083698199259 0.1676349484813153 0.8668704753289305 1.0 0.9212765721068968 4 O95831 1 +Nop, C-terminal domain [IPR042239] 0.3491735537190044 0.1580721598701921 0.8743999379810459 1.0 0.9263715714168328 3 Q9Y2X3,Q8WWY3 2 +Nop domain superfamily [IPR036070] 0.3491735537190044 0.1580721598701921 0.8743999379810459 1.0 0.9263715714168328 3 Q9Y2X3,Q8WWY3 2 +AF1104-like superfamily [IPR036075] 0.3413986426674515 0.1467998533290995 0.883290000456469 1.0 0.930655696311624 2 Q9H993 1 +TBP domain superfamily [IPR012295] 0.3541659203177628 0.1449663451649287 0.8847374437181488 1.0 0.930655696311624 6 Q9UBF2,Q9Y678 2 +Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028] 0.3541659203177628 0.1449663451649287 0.8847374437181488 1.0 0.930655696311624 6 Q9UBF2,Q9Y678 2 +Transcription elongation factor S-II, central domain superfamily [IPR036575] 0.3423848878394395 0.1403929756673826 0.8883495074941021 1.0 0.9311095856955546 3 P23193,Q9BTC0 2 +Leucine-rich repeat domain superfamily [IPR032675] 0.4012613737987985 0.1388849402676416 0.8895410715526961 1.0 0.9311095856955546 29 Q8N1F8,Q13641,O94813 3 +G protein alpha subunit, helical insertion [IPR011025] 0.337271116361498 0.1106929028382559 0.9118598741082032 1.0 0.9461353192621704 5 Q14344,P04899,P29992,P08754 4 +PUA-like superfamily [IPR015947] 0.3493148136294562 0.1087008342581242 0.913439780135475 1.0 0.9461353192621704 9 Q9P016,O43252,P41214,Q9Y221 4 +Chaperone J-domain superfamily [IPR036869] 0.3592574675687746 0.084397857816252 0.9327401104262768 1.0 0.9601458482199569 16 Q99543,O60884,Q8IXB1 3 +Acyl-CoA N-acyltransferase [IPR016181] 0.3349234897088078 0.0674555857635896 0.946219018874557 1.0 0.9700893271206356 10 O95251 1 +EF-hand domain pair [IPR011992] 0.3800355827933648 0.0268186830062071 0.9786043516929712 1.0 1.0 55 P80303,P60660,Q9H4M9,Q9Y680,O43852,Q14257,Q9H223,P14649,P17655,Q9BRK5,O75071,P07384 12 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.2744982290436916 0.0140948834049268 0.9887542825025866 1.0 1.0 3 Q15436,O95487 2 +HAD-like superfamily [IPR036412] 0.3487142073838417 0.0105875833888864 0.9915524885014292 1.0 1.0 24 Q9NQ11,P35670,Q04656,Q9H0R4,Q8NB49,Q05D32 6 +HAD superfamily [IPR023214] 0.3487142073838417 0.0105875833888864 0.9915524885014292 1.0 1.0 24 Q9NQ11,P35670,Q04656,Q9H0R4,Q8NB49,Q05D32 6 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b1113a5153eff3cab993abc66e52c12feada6adf --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase delta/epsilon subunit, C-terminal domain superfamily [IPR036794]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily [IPR036939]", "Copper type II, ascorbate-dependent monooxygenase-like, C-terminal [IPR014784]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Decaprenyl diphosphate synthase-like superfamily [IPR036424]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F0F1 ATP synthase delta/epsilon subunit, N-terminal [IPR036771]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GT29-like superfamiliy [IPR038578]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-glutamyltranspeptidase, large subunit, C-terminal domain [IPR043138]", "Gamma-glutamyltranspeptidase, small subunit [IPR043137]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Lipid transport protein, beta-sheet shell [IPR015819]", "Lipovitellin-phosvitin complex, superhelical domain [IPR011030]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "Mir domain superfamily [IPR036300]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin biosynthesis MoaE subunit superfamily [IPR036563]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHM/PNGase F domain superfamily [IPR008977]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily [IPR023397]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Snake toxin-like superfamily [IPR045860]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Somatomedin B-like domain superfamily [IPR036024]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thrombospondin type-1 (TSP1) repeat superfamily [IPR036383]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "Tumor necrosis factor alpha-induced protein 8-like superfamily [IPR038355]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vitellinogen, beta-sheet N-terminal [IPR015816]", "Vitellinogen, open beta-sheet, subdomain 1 [IPR015817]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain [IPR044920]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKB", "B4GALT1", "B4GALT3", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCKDHA", "BCKDK", "BCL2L12", "BCOR", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOLA3", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2L", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM129B", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K2", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF2", "MTERF3", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCDN", "NCEH1", "NCL", "NCOA5", "NDC80", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAB1", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEK9", "NELFE", "NENF", "NEO1", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRDE2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATZ1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLEKHA5", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP8", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIAE", "SIL1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMS", "SMU1", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5L1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX3", "STX4", "STX5", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMEM63A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXN2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VWA8", "WAPL", "WARS", "WARS2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WRAP53", "WRAP73", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZCCHC3", "ZFR", "ZFYVE16", "ZMYM1", "ZMYND8", "ZNF148", "ZNF281", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["AARS", "ACP2", "ADAMTS1", "AIFM1", "AK3", "AKT1", "AKT2", "ANKFY1", "APLP2", "APP", "ARMT1", "ARPC4", "ATP11C", "ATP13A2", "ATP1B3", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "BCOR", "BROX", "CADM1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CARM1", "CD2BP2", "CD47", "CLCN3", "CLCN6", "CLPB", "COG8", "COLEC12", "COPG1", "COPG2", "COX15", "CPSF3", "CPVL", "CTBS", "CTDSPL2", "CTSA", "CTSB", "CTSC", "CUL1", "CUL4A", "CUL4B", "CXADR", "DERL1", "DIAPH1", "DIAPH2", "DIDO1", "DNAJA2", "DNAJC10", "DNAJC2", "DNM3", "DSC3", "DSG2", "DTNA", "DYNLL2", "ECE1", "EFCAB14", "EHD1", "EHD4", "EHMT1", "EIF2D", "EIF4E2", "ELOA", "EPHA7", "EPRS", "ERAP1", "ERAP2", "EXT2", "EZR", "F11R", "FKBP7", "FTO", "FUCA1", "FUCA2", "GAA", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GBA", "GINS3", "GLA", "GLB1", "GNA11", "GNA13", "GNAI2", "GNAI3", "GUSB", "HDAC1", "HDGFL2", "HDHD2", "HECTD1", "HEXA", "HEXB", "HINT2", "HLA-A", "HLA-B", "HLA-C", "HSP90AA1", "HSP90AB1", "IGF1R", "IGF2R", "INTS11", "INTS9", "ITGA6", "ITGAV", "KAT7", "KIAA0319L", "KIDINS220", "LACTB", "LGALS3BP", "LNPEP", "LRP1", "LRP2", "LRSAM1", "MAN2B1", "MANBA", "MARC2", "MCAM", "MFGE8", "MFSD10", "MPP2", "MRC2", "MRPL23", "MRPL45", "MSH3", "MSH6", "MTPN", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "NAE1", "NAGLU", "NAP1L4", "NECAP2", "NEDD4", "NEK9", "NEO1", "NF1", "NIP7", "NIPSNAP1", "NLN", "NME6", "NOP58", "NPC2", "NUCB2", "NUTF2", "OTUD6B", "PAPSS1", "PARN", "PFKM", "PFKP", "PFN2", "PGAM5", "PKM", "PLA2G15", "PMPCA", "POLA1", "POLD1", "POLG", "PPT1", "PPT2", "PRCP", "PRPF3", "PRPF31", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSME1", "PSME3", "RABGAP1", "RCC2", "RCN2", "RP2", "RPL15", "RPL23A", "RPL37", "RPL37A", "RPS9", "RRM2B", "RUFY3", "SCPEP1", "SDF4", "SEC23A", "SEC24A", "SEC24B", "SET", "SIAE", "SLC18B1", "SLC19A1", "SLC30A5", "SLC3A2", "SLC4A7", "SLIT2", "SRP54", "STK11IP", "STOM", "STX3", "STX5", "STX6", "STX7", "SUPT6H", "SV2A", "TBC1D4", "TCEA1", "TEFM", "THOP1", "THYN1", "TIMM44", "TLN1", "TMEM115", "TPBG", "TRAP1", "TSPAN3", "TSPYL1", "TUBB2A", "TUBB6", "TUBG1", "UBA2", "UBA6", "UBE3C", "UBR5", "UGCG", "UQCRC2", "USP15", "VCL", "YARS2", "YTHDC2", "YWHAB", "YWHAE", "YWHAH"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2c964b31ac015298beea54e03b3f12c2af59789d --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86e72d18469173252278dc0ccecc494e971b1ec6d2d98a3fef2f24fdc9bba638 +size 75845 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6c46fade60030a0821d16299a62ea31687d97bd1 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 4.0 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..19d66ce486bd8b32031f9d48dc3e6d4cecea00c5 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..59b45b896a44e206c6a9f83039a40e1dae580709 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EGF-type aspartate/asparagine hydroxylation site [IPR000152] 0.9822904368358906 2.8982953765737274 0.0037519704859774 0.0149236293207681 0.0150078819439096 3 P98164,Q07954 2 +P-type ATPase, phosphorylation site [IPR018303] 0.6820134862686268 1.5346190563626263 0.1248774289329683 0.4134898381974005 0.1665032385772911 10 P35670,Q04656,Q9NQ11,Q8NB49 4 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bb83ef2abf0db9cca554195e6f2cbd1c1c53c445 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7A", "ATP7B", "EIF5A", "FASN", "LRP1", "LRP2", "NDUFAB1", "SLIT2"], "leading_proteins": ["ATP11C", "ATP13A2", "ATP7A", "ATP7B", "LRP1", "LRP2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..10762463f590b74e51e7af84497d085620fdf8e7 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ankyrin repeat [IPR002110]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1658c46460b8617b73d7ea492f8ee6ec2ccda645 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf097a38d52679afbed82c7af1aad655a723ddc5ba79fd33da27435eecfdf2bb +size 138422 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e3b24161e7e0bda8091d1931596c389957efc7ec --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2f32a05a435d1355fb911a20593e19b172367025ea9bcd5c09e12682e974041 +size 85600 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4699a0dc5d49742e71b7ac737bb88e7916eee9f0 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 76, + "title": "Average number of proteins per term", + "value": 5.7368421052631575 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3527856e2b8efa8dd9c8f28ee70f4a0c913dacd9 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c4a3eb00df24965ed54d2ce44d51ac4a6e1acb9 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,15 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +LDLR class B repeat [IPR000033] 0.991147831218648 2.9371013021284593 0.0033129586355289 0.2229129148334238 0.0344154150890374 2 P98164 1 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.9781399349451608 2.881334323420639 0.0039599535863206 0.2603320703395145 0.0344154150890374 3 P98164 1 +Integrin alpha beta-propellor [IPR013519] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.5769703986818746 0.057030807409944 2 P23229 1 +FG-GAP repeat [IPR013517] 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.5769703986818746 0.057030807409944 2 P23229 1 +Importin repeat 6 [IPR041389] 0.7722041900265608 2.001667028904122 0.0453205547230406 0.9705438841791764 0.1497548764761342 2 O00410 1 +Importin repeat 4 [IPR041653] 0.7722041900265608 2.001667028904122 0.0453205547230406 0.9705438841791764 0.1497548764761342 2 O00410 1 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.761372201924719 1.9459037343212715 0.0516663042979006 0.9822560694500212 0.1510245817938634 3 Q8TD19 1 +Leucine rich repeat 4 [IPR025875] 0.7075044145119117 1.6986852615006456 0.0893785019019246 0.999187767574814 0.1937755835759426 3 Q8N1G4 1 +HEAT repeat [IPR000357] 0.6315319181694632 1.3168747998579249 0.1878805947772936 0.9999998647580328 0.3245210273425982 6 O00410,P30154,Q8TEX9 3 +Proteasome/cyclosome repeat [IPR002015] 0.5674240188846353 1.049779793999935 0.2938193673097475 0.999999999996707 0.4378484689321728 2 Q13200 1 +Leucine-rich repeat, typical subtype [IPR003591] 0.54119755034572 0.8210525989915219 0.4116163082052542 1.0 0.530217617349141 15 Q13641,O94813 2 +Ankyrin repeat [IPR002110] 0.4505263381707571 0.3872412271917852 0.6985776315288139 1.0 0.8069553617055976 18 P58546,Q9H9B1,Q9P2R3,Q9ULT8,Q6W2J9,Q9ULH0,Q9H078 7 +Tetratricopeptide repeat 2 [IPR013105] 0.4199645599527499 0.3699834009332534 0.7113948583457241 1.0 0.8069553617055976 5 Q02790,Q6P3X3,Q13325,P31948 4 +Leucine-rich repeat [IPR001611] 0.4147247386932752 0.205988536998051 0.8367998654493336 1.0 0.9216926054224543 25 Q8N1F8,Q13641,O94813 3 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..05ff437183566eb52e08dae61ad13c5cf67ebc51 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Thrombospondin type-1 (TSP1) repeat [IPR000884]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "ADAMTS1", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKS1A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "BCOR", "BIRC6", "BOP1", "BTRC", "BUB3", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EHMT1", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HUWE1", "IFIT5", "IGF1R", "IGF2R", "ILK", "IPO4", "IPO5", "ITGA6", "ITGAV", "JUP", "KAT7", "KDELC1", "KDELC2", "KEAP1", "KIAA1468", "KIDINS220", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LLGL1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MIOS", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGFR", "OGT", "OSTF1", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PAM", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SIN3A", "SIN3B", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STK11IP", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIM32", "TTC1", "TTC19", "TTC27", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", 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0.4866123827014424 0.1245886422942042 0.0649093548344762 +Central nervous system development 41 199 2.871599773393952 0.0040839983778193 33.77669902912621 185.99757281553397 -0.0141558138034019 0.824882104002827 10.884149015113811 18.9886909095464 0.5269565923883169 0.2626934247198993 0.0095632706840235 0.0343280904297913 0.01850854857981 0.0944221157740919 0.0165217260760765 +Animal organ morphogenesis 22 110 2.8640355098097463 0.0041828111761788 19.361650485436893 96.08252427184466 -0.07235094891032 0.7437722143004032 7.630278544978294 13.241336623234048 0.6349578991360847 0.292190269554689 0.0525652808279587 0.9314945216867722 0.1378325374259356 0.3118194649963628 0.5944134376268635 +Oligosaccharide catabolic process 4 5 2.85111309356104 0.0043566470909617 1.2014563106796117 2.3567961165048543 -0.2432795754240238 0.3143165980698041 0.9220585957066318 0.7767104064700684 1.6605983377562186 0.3028711577291625 1.5324328016370272e-05 0.0004872428921227 2.747580602519606e-07 1.6508481534675058e-07 5.11944457815466e-06 +Ganglioside metabolic process 4 5 2.85111309356104 0.0043566470909617 1.7718446601941749 3.2524271844660193 -0.1775376367083389 0.2846388467168437 0.9835459402825288 0.5697631359658722 1.612139414180225 0.2969406455967822 2.2636308823174428e-06 0.0017760204843955 5.369271916582234e-06 8.971938182982207e-06 0.0002457979454447 +Multi organism reproductive process 36 159 2.8479028493508496 0.0044008356608595 28.98543689320388 149.51941747572815 0.0785058313564837 0.8092777812776505 10.55382788667465 13.727836918348864 0.5250971386268368 0.2696355204869683 0.0113200167635553 0.0836507387613992 0.0399879228856311 0.0030221342180405 0.0032437694090572 +Regulation of hydrolase activity 28 176 2.802965645249372 0.0050635062751109 34.9126213592233 168.98543689320388 0.0619050191092553 0.7830965788802455 11.250982089704202 16.868128778807822 0.6662391316189477 0.3027620005678602 0.032809364425359 0.0016789505394353 0.0485881299390942 0.0229660812850454 0.2299226904618627 +Regulation of cellular component movement 36 153 2.7986564306860844 0.0051315706290102 30.009708737864077 147.12864077669903 -0.3953306605752169 0.6081571166461066 11.555056175377826 17.394633004918873 0.8090661968501279 0.3300486598477032 0.1224756118698653 0.269888949574062 0.0139437456123694 0.002960296601752 0.0124847961718456 +Response to peptide 14 101 2.791135677320497 0.0052523450259565 20.094660194174757 96.66019417475728 0.1432899082124719 0.7803896401267801 7.902517150358895 10.059824351434456 0.600783122030622 0.2900989611756318 0.1809292675965228 0.0126790937275429 0.1407784844209791 0.046756971116833 0.3148490146570889 +Carbohydrate derivative metabolic process 44 282 2.789360591044909 0.0052812227793452 52.560679611650485 256.59223300970876 -0.2905800319656845 0.6714103222597233 16.554227088257075 23.412587641314047 0.9410140760631216 0.3434766696433585 1.196304444199098e-05 0.0049552180983358 1.2371673641978628e-06 1.251152976582992e-08 8.875237056060316e-05 +Regulation of protein catabolic process in the vacuole 3 5 2.7880156866114048 0.0053031975855937 1.2014563106796117 3.3762135922330097 0.3553822840909967 0.3561494889357127 1.140898051797836 1.3189129213804007 1.3434272672921512 0.3030873575434169 0.0820419193359714 0.0012601973854463 0.0047533286028597 9.854683287521486e-05 0.0013781701696679 +Regulation of lysosomal protein catabolic process 3 5 2.7880156866114048 0.0053031975855937 1.1820388349514563 3.344660194174758 0.359320837781623 0.3612070071329659 1.1335003430162958 1.3137235419699895 1.333216779855555 0.3035682445298419 0.0676363609296167 0.0008300469730069 0.0031504918831051 3.9104524570814734e-05 0.0005688349419973 +Cell morphogenesis involved in neuron differentiation 25 95 2.783988892678627 0.0053694872918468 19.59223300970874 91.78155339805824 0.0633940435481119 0.7404601122693133 9.411763856852913 11.295279945325175 0.755341800166473 0.30636858572397 0.0212286643194971 0.0079595449794831 0.0579452604895439 0.3794656743271232 0.0711206903762447 +Cell part morphogenesis 29 126 2.7811564613265034 0.0054165624910764 26.983009708737864 118.6019417475728 0.0053227567796788 0.7443384780209938 11.4203532612418 14.976414989521164 0.7256117492835441 0.3075338103498531 0.0185565067491785 0.0048778291461451 0.0563623421842366 0.4853913262885576 0.073658877589722 +Cell migration 45 224 2.776298299838023 0.0054981737867776 41.199029126213595 207.86893203883497 -0.2981448387208389 0.7157251580036387 14.912827573665234 24.119993435436054 0.6177562494844211 0.3044944011275939 0.0881906416201311 0.1948054803076664 0.0418104535205659 0.0111860924033019 0.0366295062981355 +Response to endogenous stimulus 63 285 2.775427734908816 0.0055129149449679 52.060679611650485 278.3033980582524 -0.0574210767621067 0.8142217503475416 19.652903328690797 29.262333522986196 0.5425193479116073 0.2778283155224302 0.0182494026925238 0.0269702430064546 0.0440108841162312 0.0404746896718932 0.187934138920952 +Glycolipid catabolic process 6 8 2.766993420927579 0.005657589688405 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 1.8648451672862943e-08 2.460833692014816e-07 5.558079816224799e-08 3.305842675796101e-09 3.903860956515125e-07 +Cellular component morphogenesis 32 142 2.7658031796785902 0.0056782794828746 29.817961165048544 132.93446601941747 0.0314200755217484 0.7461931622021263 12.05361677657582 16.684335902896763 0.7312955885385684 0.3072439636957093 0.0343142449389874 0.0091313684637448 0.0960421013700108 0.2976743521560225 0.0732682832238834 +Ceramide catabolic process 6 8 2.765340247852905 0.0056863449776103 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 1.8648451672862943e-08 2.3666612945957126e-05 5.558079816224799e-08 3.305842675796101e-09 3.903860956515125e-07 +Glycosaminoglycan catabolic process 4 5 2.763881748937243 0.0057118234861841 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 7.064341089644265e-05 0.0526645480715484 0.0001343549216781 3.3521637524966083e-06 9.569573614901708e-05 +Aminoglycan catabolic process 5 6 2.76291416402294 0.0057287829830003 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 1.576396912287629e-06 0.0015075035399645 3.74476751148508e-06 1.5938034825404938e-07 9.139729707100432e-06 +Locomotion 50 260 2.7401598871579966 0.0061409302770134 50.101941747572816 240.06553398058253 -0.349951337932897 0.6813582364350985 17.46381268541236 28.22238449973331 0.6313838669711923 0.3105410696261587 0.0586517670864347 0.1762028731615915 0.0353682728032653 0.0128004192913965 0.0650437162195018 +Cellular protein catabolic process 61 247 2.705043235060258 0.0068295499928689 52.41990291262136 236.80339805825244 0.1673159010482066 0.8063536769071427 19.666167587086957 24.460046442072542 0.8282412046097252 0.3133286292668994 0.129413531999891 0.2118787247864206 0.0469845352871284 0.0083608661558065 0.0037198977601551 +Aminoglycan metabolic process 16 20 2.702842361939513 0.0068749342836007 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 3.3713135015407324e-11 0.0034245890280422 4.5299562884691354e-13 5.88732310750797e-14 3.418107688018718e-09 +Ion homeostasis 23 120 2.691688941350032 0.0071091216918277 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0002290270982953 0.0790201295742995 0.0012910468424855 0.0071444596915644 0.010915878503258 +Glycoside catabolic process 4 6 2.671957141783708 0.0075410279147687 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 2.4381976348781024e-05 6.108202829893653e-06 4.656667989155393e-05 4.314873622219065e-07 1.3106068439724131e-05 +Membrane lipid catabolic process 8 12 2.6543469017140047 0.0079462089051558 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 9.139590672438014e-11 2.3399875141854645e-06 4.26979399217471e-10 3.4298579976604223e-10 1.4497628230363953e-07 +Oligosaccharide metabolic process 8 10 2.636890651392759 0.0083669798067687 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 7.411846041084213e-07 0.0001834080308804 1.318928736769531e-09 1.5654279498709818e-09 6.187339250462871e-07 +Synaptic transmission gabaergic 2 5 2.6251868645152983 0.0086601424961156 1.3422330097087378 4.519417475728155 0.2347132009622901 0.5263821702803212 0.9813122104836663 1.053017693397039 0.9634597836833804 0.3045939104536951 0.0113156335852872 0.0981765691424607 0.0170518298819148 0.0136772183990335 0.0790607116166092 +Growth 47 172 2.625081104847057 0.0086628329601186 32.35436893203884 170.2378640776699 -0.1299328758980621 0.8216102277249375 13.014019898637835 19.489522285909977 0.4514813719804424 0.249171156117785 0.288952924763973 0.15098636215256 0.1899010984062833 0.0241902244482153 0.0714345461259977 +Regulation of vesicle mediated transport 22 121 2.6137042349130426 0.0089566534191911 24.555825242718445 117.33252427184466 0.2091879024365628 0.7679552913580993 8.949930305556254 13.223750714091672 0.6695514077553656 0.3058083256414907 0.257745740466159 0.079701490259028 0.1010569970097573 0.0630720103088162 0.0341004213994648 +Negative regulation of developmental process 31 113 2.613157922831881 0.0089709838901641 22.606796116504853 101.0631067961165 -0.1690080981071963 0.631864255638976 9.924264293838888 11.641526693087815 0.7921494883239464 0.3166468220789081 0.059208803213038 0.0683277707777694 0.1416307685512452 0.2069784841374473 0.3455836325200705 +Mucopolysaccharide metabolic process 8 12 2.600448055048179 0.0093102112989715 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.0050278920299668 1.0 6.670129789082706e-05 1.063215827507647e-06 0.0002580266226921 +Aminoglycan biosynthetic process 7 11 2.5928570591189546 0.0095182321378772 3.0800970873786406 8.300970873786408 0.6387272076133388 0.2830924102482349 1.486473637192798 1.7113836533227735 1.3163721030030058 0.2655273000426038 0.0041358171170037 0.1868885334554594 4.751170414271537e-05 6.314511987814461e-06 0.000798592209508 +Tube morphogenesis 23 113 2.585702534293853 0.0097180759573725 22.553398058252423 105.08252427184466 -0.2488475563536041 0.6597182087919149 8.854792082377324 14.052881590858595 0.694754649989587 0.3019442459833162 0.1730356540162915 0.4272527228379353 0.1848221007883708 0.1331190927219059 0.4921457715029377 +Tube development 30 148 2.5825089145259743 0.0098084828163913 28.25485436893204 136.24514563106797 -0.3501984518285801 0.641205174580618 10.588994136529294 17.09711270486538 0.6980168994211606 0.3056669474158256 0.1842372436713427 0.3415838212885058 0.2213217219470151 0.1467228383845069 0.3923222725138781 +Positive regulation of cell population proliferation 27 129 2.578294901879828 0.0099289221807017 23.140776699029125 121.61650485436893 0.1282520970025829 0.7868148483142368 8.642275150970844 14.153236256129588 0.5757824945356146 0.2881040498238528 0.2858882062318097 0.3952381026757636 0.4570028105771068 0.0967009391370131 0.0616928017032221 +Proteoglycan metabolic process 8 11 2.578171059454009 0.0099324815237742 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.0436242991079327 1.0 0.0080456420559546 7.596469967417165e-06 0.0001790277584403 +Proteoglycan biosynthetic process 7 10 2.57274409265156 0.0100895780375416 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 0.2386769792225308 1.0 0.0443091130960601 1.7385968628801138e-05 0.0002147363626889 +O glycan processing 4 6 2.5702902687663225 0.0101613334011843 1.8762135922330097 5.029126213592233 0.779006640385936 0.3319918611732407 1.1540209287066336 1.1758600296433448 1.0243123329907684 0.2736840802111854 0.1704659530663174 1.0 0.0219975904219434 0.0002379581347217 0.0052134507581354 +Cellular response to nitrogen compound 28 141 2.5563661600250205 0.0105771752177943 29.37864077669903 133.67233009708738 -0.0913440289593822 0.7339643029629616 11.993620071702985 14.495292553830469 0.617621954267992 0.2893340104916694 0.2033192530160606 0.0469324428919216 0.1925466019749329 0.1160623149114901 0.2421235941629798 +Lipoprotein localization 6 7 2.5434845750498845 0.0109752902731661 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.0891620654695603 0.0573151884822011 0.0056684159955205 1.5938034825404938e-07 3.903860956515125e-07 +Heparan sulfate proteoglycan metabolic process 3 6 2.5416238946609004 0.0110338833131198 1.766990291262136 5.121359223300971 0.5642898647972117 0.4173053251695717 1.1613006057834978 1.389918659730618 1.0230121456430192 0.3027926697750463 0.1639736616263024 1.0 0.1993869387044997 0.0175758241055335 0.0233101974365333 +Heparan sulfate proteoglycan biosynthetic process 3 6 2.5416238946609004 0.0110338833131198 1.7160194174757282 5.026699029126213 0.5645930836787868 0.419729099473023 1.1572631253827 1.3516497566885952 1.0187409340025655 0.3042431327777389 0.1374990224216387 1.0 0.1677870330809631 0.0103266247469619 0.0118865434534573 +Vasculature development 22 101 2.5339218927689666 0.0112793870145011 20.354368932038835 95.0 -0.2304125656009934 0.6533759527787552 8.394731087929287 11.260378168820724 0.7092119435529696 0.3032836594411232 0.0861089548481109 0.3071955566163423 0.0863832947265474 0.1031989261337172 0.213482066273081 +Defense response 38 216 2.53005947014921 0.0114043195021491 39.067961165048544 208.97087378640776 0.011010237525631 0.8146618852499709 12.660052712295611 20.371289672620577 0.5963961283752253 0.287612323458898 0.0276380887732811 0.2109923157248617 0.0465543060406986 0.0082029447936585 0.048766023344233 +Reproduction 48 238 2.517905074218296 0.0118055133162602 43.5 227.48058252427185 -0.219773656527146 0.787557141924658 15.835087622113116 21.77225703411786 0.5407434121319004 0.280748801863037 0.0039936772195916 0.0253985364246335 0.0232597568202745 0.0204362320232708 0.0057911006175046 +Protein catabolic process in the vacuole 6 9 2.508999269142393 0.0121073734899239 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0102892388568492 0.0001192904084611 3.4550328168080166e-05 2.738219955089598e-07 2.7180346417726147e-05 +Lysosomal protein catabolic process 6 9 2.508999269142393 0.0121073734899239 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0083688347592164 8.597904339497348e-05 2.214575962840231e-05 1.171981080376947e-07 1.2147954097366526e-05 +Astrocyte development 2 5 2.506344904444433 0.0121986561796911 1.662621359223301 5.529126213592233 0.4384947546692366 0.3812983981533123 1.2148997810479618 1.4027110413850483 1.1577934925672642 0.2956958593053811 0.1307520596304716 0.0034296220851759 0.0126574737404708 0.0088528623379573 0.0097510399506001 +Positive regulation of cellular component organization 49 254 2.5033657528637256 0.0123018340426248 48.478155339805824 241.9393203883495 -0.1464361847523485 0.835549698883611 19.618250085138943 24.91887239583436 0.4331063834071303 0.24452439389647 0.1641708460371516 0.0498182988164074 0.2174771218350915 0.0762964427299735 0.011001265397057 +Head development 45 163 2.499044375479035 0.0124528716437652 28.189320388349515 152.3106796116505 0.0059124933604433 0.813758893034913 8.884265710120951 16.06224489878714 0.5138144173868527 0.2607809922640906 0.0440446654967701 0.241652137491249 0.1187713522281889 0.2645978046531626 0.0250353597903843 +Negative regulation of catalytic activity 24 154 2.483774684443233 0.0129998032037517 34.08980582524272 151.1626213592233 -0.3158672068434343 0.6409517007790445 13.863558186604337 15.317363106812854 0.7535911575630369 0.3204754228952886 0.0495316217615806 0.0048168782591284 0.0557486656710861 0.0091357637871845 0.1058140939193525 +Regulation of immune system process 36 197 2.4832145432124064 0.0130202642913477 36.87864077669903 188.16504854368932 -0.0031957292679856 0.8119722777308811 12.646801280107608 20.553787871616997 0.5631604432463234 0.2782883351514524 0.0273822499643457 0.2101071978679376 0.0088908411204549 0.0021428640636613 0.0328027209149644 +Chloride transmembrane transport 3 5 2.4737952384568835 0.0133686293581885 1.9271844660194175 5.497572815533981 1.0121969151812915 0.2503571453769561 1.6864793094247907 1.5080669592016671 1.1003731395705292 0.2453144412674818 0.1239529915803282 1.0 0.1515272625734178 0.3422564852890665 0.0078812527225172 +Lysosomal lumen acidification 4 5 2.4711849348932664 0.013466615718267 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 7.064341089644265e-05 0.0526645480715484 0.0001343549216781 9.854683287521486e-05 9.569573614901708e-05 +Positive regulation of multicellular organismal process 36 205 2.4706313457276905 0.0134874778998637 39.01699029126213 197.18446601941747 -0.1485555770791877 0.7987469369478079 12.944136981807215 18.82443030137102 0.4614700428477258 0.2559274460276268 0.169738440073276 0.0517785196826843 0.1308280712555692 0.1794568196885945 0.0824879738747941 +Positive regulation of locomotion 27 87 2.462976649029229 0.0137788889364711 17.813106796116504 82.76941747572816 -0.0202856110636012 0.6872652647880098 6.785301293884359 10.926397031402892 0.7474886342310336 0.3042029503813403 0.0289723419749144 0.1828350446371612 0.0696200653310784 0.0027915620299469 0.0003229410282765 +Insulin like growth factor receptor signaling pathway 2 5 2.457296470912511 0.0139987107681658 1.614077669902913 3.837378640776699 -0.2487144344748098 0.4995908195408873 1.1208941791969826 0.884198349189158 1.033346086853097 0.321306579089889 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.0565188023636715 0.0397387250697101 +Regulation of pinocytosis 1 5 2.455274373280936 0.0140777094487256 0.8106796116504854 3.7597087378640777 0.6023630922876955 0.3350485208266608 0.9669703082116616 0.8261666729401809 1.2571257052071827 0.2840319551692356 0.0025621931302305 0.0479914252810258 0.0039135152062846 0.0233125205204954 0.0817606313480972 +Positive regulation of pinocytosis 1 5 2.455274373280936 0.0140777094487256 0.8106796116504854 3.7597087378640777 0.6023630922876955 0.3350485208266608 0.9669703082116616 0.8261666729401809 1.2571257052071827 0.2840319551692356 0.0012138747028233 0.0338360956076009 0.0018609890552042 0.011414919510753 0.0419919493306108 +Neuron maturation 1 6 2.45326970771312 0.0141564152125654 1.6966019417475728 5.737864077669903 0.3884050692002241 0.3270287101850628 1.1310653568868725 1.188220216330287 1.2760249805885358 0.2674215567147113 0.0158457649983195 0.0065792573185243 0.0237627189197599 0.1227655047468798 0.3442759855295882 +Cellular response to amyloid beta 3 7 2.4425894743990377 0.0145823144096031 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0134972023129384 0.0001834080308804 0.0013262573806951 0.0175758241055335 0.0233101974365333 +Response to amyloid beta 3 7 2.4425894743990377 0.0145823144096031 1.8713592233009708 5.91747572815534 0.2206633711995859 0.4678383207618323 1.2867717931543454 1.328545973894273 1.1144604515178314 0.3257294628423651 0.0134972023129384 0.0001834080308804 0.0013262573806951 0.0175758241055335 0.0233101974365333 +Golgi to lysosome transport 1 5 2.4404165231659776 0.0146703360514759 1.6504854368932038 4.604368932038835 -0.1604261304839933 0.5036105221859368 1.18205627865361 0.6319029203780867 1.034869173369558 0.3241536231264675 0.0748668240169799 0.0479914252810258 0.0039135152062846 0.0233125205204954 0.0817606313480972 +Regulation of growth 36 125 2.43987742383327 0.0146922461998568 22.73543689320388 120.90533980582524 -0.0689505072147438 0.7681860873791975 9.226934325231433 13.173534465792589 0.5432162852037127 0.2746634934328097 0.1897729520322741 0.1266493317341842 0.0846240673284839 0.0310694496565362 0.068508760919285 +Aorta development 1 8 2.43700215331876 0.0148095911736685 2.308252427184466 6.759708737864078 -0.0774176458664225 0.5304235266925468 1.8287429643020912 1.3840379619847545 0.941147128750552 0.3090353654428162 0.2562984571775746 0.0148056693212618 0.0513963234576887 0.2359805031570881 0.5569491745948094 +Glycosphingolipid metabolic process 10 14 2.436344974953434 0.0148365274832031 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 4.9205512370228445e-06 0.0005458668398673 1.4194050004739812e-05 1.7052194394220647e-10 2.3120914428411725e-07 +Positive regulation of immune system process 14 112 2.433631649581698 0.0149481984057777 24.063106796116504 111.55825242718448 0.0014586405879444 0.7484751661806336 8.418420513377251 11.253004123360045 0.6663856016863496 0.2941180973009932 0.0731016002025043 0.1141642055567186 0.0721021454226883 0.0436565370904987 0.2958209632558213 +Peptide catabolic process 7 12 2.412510132307133 0.0158430970781515 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0003967304077019 0.0001017478453213 0.0007461625149634 7.191102350304072e-05 8.330005699696703e-08 +Regulation of chondrocyte differentiation 1 5 2.410819418227094 0.0159167270359401 1.2475728155339805 4.645631067961165 0.3908763682458222 0.4779315096844677 1.015352505643885 0.7278478315080003 0.9243828894835806 0.2898833830307916 0.1769084608978667 1.0 0.2147385524083838 0.1227655047468798 0.3442759855295882 +Regulation of cartilage development 1 5 2.410819418227094 0.0159167270359401 1.3033980582524272 4.985436893203883 0.3743277422969007 0.4941420997253845 1.0463473716372358 0.95010554007419 0.906862347569532 0.2911725749248034 0.2386769792225308 1.0 0.2872333566147377 0.2089591760219589 0.5122684088981724 +Antigen processing and presentation of exogenous peptide antigen 2 5 2.394536126732385 0.0166414039614242 1.6067961165048543 4.686893203883495 0.987028524507588 0.2895214995402835 1.1019631322504793 1.05964046762731 1.0509935492639806 0.2645206747413269 0.0102892388568492 0.0042324529563037 0.0155240337321844 0.0119341177484456 0.0701952648708137 +Presynapse organization 1 5 2.3918624168630176 0.0167631248870285 1.75 4.810679611650485 -0.0786825733773425 0.4906970601701207 1.287778624767381 1.276403672136879 1.0294513711949584 0.3065171659690148 0.1574312068776012 0.1026081339138497 0.191600110602388 0.0990342687178565 0.2898287915273368 +T cell differentiation involved in immune response 2 5 2.384683135699178 0.01709383753418 1.6310679611650485 4.381067961165049 0.0779130978869904 0.5404950204177928 1.1426446182154013 0.735989410832118 0.9413992671049548 0.3109028421032308 1.0 1.0 1.0 0.1562190614045352 0.1645088237572309 +Zymogen activation 1 7 2.3846194288604887 0.0170967976242404 1.7402912621359223 8.048543689320388 0.2681171507749159 0.4816463680963982 1.616969451297242 1.3644490390373976 0.9797969023910962 0.2836022963171947 0.0238386467818615 0.0100088432903632 0.0354914601129098 0.1735315682069146 0.4482773855235765 +Positive regulation of myoblast fusion 4 5 2.370964377714796 0.0177417409303828 1.3422330097087378 4.364077669902913 0.4248698403591905 0.5017887244438167 1.0620838941127295 0.7873211763594862 0.9211907465046666 0.309128603452281 1.0 1.0 1.0 0.1788587842302525 1.3106068439724131e-05 +Regulation of myoblast fusion 4 5 2.370964377714796 0.0177417409303828 1.3422330097087378 4.364077669902913 0.4248698403591905 0.5017887244438167 1.0620838941127295 0.7873211763594862 0.9211907465046666 0.309128603452281 1.0 1.0 1.0 0.1988473022417859 2.8311070051942505e-05 +Biological process involved in interspecies interaction between organisms 40 276 2.3702279836189017 0.0177771196697773 50.94660194174757 266.20873786407765 -0.3024547258965843 0.7200706623473742 19.367976349393754 23.426711195473835 0.5504458582743598 0.297743082775899 0.1004448323288851 0.0219261304556315 0.0408449468439132 0.0044752063943488 0.0293539641886394 +Artery morphogenesis 3 7 2.3659112724940377 0.0179857542748522 1.8446601941747576 5.497572815533981 -0.1453756942735048 0.4458938580524781 1.3220114238993363 1.9969622396143276 1.0910949618937522 0.3050258624648908 0.2791687301932883 0.0179094063189584 0.0614247268920475 0.0185450998789275 0.1451121707049519 +Glutamate receptor signaling pathway 1 5 2.365487959006367 0.0180063288141687 1.4038929440389294 3.3527980535279807 0.7859346657260975 0.3409097336053081 0.8946363168296952 1.034495401330204 1.1806249585874955 0.2993334383587996 0.1374990224216387 0.0892490045576324 0.1677870330809631 0.0768284795296569 0.2348875720984273 +Monocyte chemotaxis 2 6 2.3580356637982787 0.0183719278342919 2.4563106796116503 7.155339805825243 0.0262113076047182 0.5433439329754083 1.669408935743521 1.1449109140177045 0.94913794377158 0.3138414503322078 0.0037203118650809 0.0573151884822011 0.0056684159955205 0.0026581093268102 0.018020673376298 +Regulation of response to external stimulus 26 131 2.3531675943481845 0.018614242303518 27.32766990291262 129.63349514563106 0.3937649860570471 0.6986677015868525 9.316542933972368 15.399506498758855 0.8616366228871625 0.3591499966721317 0.0500406025238737 0.1616608674845378 0.0231471008896816 0.0093508517831507 0.0310633115569313 +Neutral amino acid transport 1 5 2.347218338521403 0.0189141675448403 2.3228155339805827 4.922330097087379 0.5168518363879385 0.3990476682843565 1.4731130220322628 0.987192944896482 1.0926945809125377 0.308136804548559 0.1769084608978667 0.1157751708195439 0.2147385524083838 0.1227655047468798 0.3442759855295882 +Skeletal muscle tissue regeneration 2 5 2.3457717930316764 0.0189877291385855 1.8106796116504855 4.890776699029126 0.1338591162181891 0.5312746316853706 1.3285814481399312 1.1213776109113207 0.9530858361170068 0.3091765164809326 1.0 1.0 1.0 0.0990342687178565 0.088385561156941 +Macromolecule depalmitoylation 1 6 2.3419983599740517 0.0191807992083825 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0037203118650809 0.0573151884822011 0.0056684159955205 0.0331187861076589 0.1125747569923622 +Multicellular organism reproduction 25 130 2.327365791493577 0.0199458048411702 23.84223300970874 120.66504854368932 0.0593603069609875 0.7798912052141721 8.513659091728568 12.574030941740885 0.5505148080533515 0.2777033666340781 0.0141457825278188 0.3289080720823409 0.0443736989784785 0.043858053709501 0.0687432925638486 +Smad protein signal transduction 1 9 2.3215297812942017 0.0202582686957988 2.9223300970873787 8.470873786407767 1.0610232243819884 0.2706100861951009 1.609675360071813 0.9712499271368484 0.9663464864325269 0.2495327076802485 0.2620823144188485 0.0155575631698287 0.0538434207197609 0.2450354162713742 0.5711827040853724 +Regulation of mitochondrial fusion 2 5 2.315203320980697 0.0206018076046217 1.5242718446601942 4.766990291262136 0.7253550907037913 0.367601169377127 1.0824698493002796 0.7815081697098348 1.0008486659137603 0.2877626014609443 0.0748668240169799 0.0479914252810258 0.0921025797166938 0.2183511668733661 0.0105668672564949 +Vacuolar acidification 7 9 2.310932458057378 0.0208365858890851 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0003359589954632 0.0847528009868792 0.0006327439593496 5.4054011518008696e-05 8.294870660489475e-07 +Neuron projection arborization 1 7 2.3027790003547883 0.0212912806389664 2.1189320388349513 6.410194174757281 0.2997181931700579 0.5356389026564765 1.6063982583137093 1.2538070031432729 0.9306716986687408 0.3086593014216465 0.0066298507200763 0.0027067874988798 0.0100519320580488 0.0565188023636715 0.1807018090276839 +Regulation of cell differentiation 53 222 2.2999207584644816 0.0214527098084114 48.99029126213592 210.2038834951456 -0.255449565969206 0.7221919123182192 20.43720913899191 22.37689482058825 0.5557991659315296 0.2848972964606696 0.2921828440650524 0.3673261456409958 0.5247540648623393 0.0592269879970167 0.1157385470420026 +Anatomical structure formation involved in morphogenesis 31 168 2.297205640918787 0.0216070414954003 32.810679611650485 157.1601941747573 -0.1912414776186605 0.7594707489104086 12.877996682995931 18.066988830438493 0.5095412420755115 0.2701966001142822 0.3539381197390239 0.8195752091361015 0.5597728430293964 0.1250703496850155 0.2636963177698097 +Cellular response to increased oxygen levels 2 6 2.293431171747633 0.0218231937242874 1.6504854368932038 6.385922330097087 1.138869139630967 0.2726341581961526 1.2184562719610088 0.8029653015671253 0.9206381175249092 0.2739573544488438 0.0891620654695603 1.0 0.1094892401774078 0.2559514735144251 0.018020673376298 +Regulation of synapse assembly 2 9 2.292104649845372 0.0218996051547089 2.5606796116504853 7.859223300970874 -0.0792788242373662 0.5395185567400329 1.7274785273339432 1.5932464806786577 0.9385185942947613 0.3087264731082229 0.0418009103002939 0.0179094063189584 0.0614247268920475 0.0816409424117451 0.3340933889960909 +Cellular ion homeostasis 21 98 2.290512932961933 0.0219915997308928 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0002475504984746 0.1493637558109807 0.0012172861714086 0.0068681967442696 0.0035272396581226 +Negative regulation of fatty acid metabolic process 1 5 2.2858411301199912 0.02226355449913 1.8567961165048543 6.237864077669903 -0.7511453360395297 0.3488555180694634 1.2488353514897588 1.7014338045407051 1.0766836748136646 0.2799575723443467 0.1239529915803282 0.0802348466038066 0.1515272625734178 0.0630532374058985 0.1985866733922443 +Cd4 positive alpha beta t cell differentiation 2 6 2.2853182918673247 0.0222941711355697 1.83252427184466 4.847087378640777 0.0335821750686967 0.5344101005518149 1.232099178367232 1.037367964290322 0.9445035588204572 0.311696213468694 1.0 1.0 1.0 0.1735315682069146 0.1889957663081205 +Regulation of syncytium formation by plasma membrane fusion 4 6 2.2750406482830043 0.0229034915189869 1.5145631067961165 4.881067961165049 0.4788760389365136 0.4988531191063783 1.1688852682318214 1.060285190268009 0.8935284827681266 0.3080127656634198 1.0 1.0 1.0 0.2373820829012167 9.569573614901708e-05 +Positive regulation of syncytium formation by plasma membrane fusion 4 6 2.2750406482830043 0.0229034915189869 1.5145631067961165 4.881067961165049 0.4788760389365136 0.4988531191063783 1.1688852682318214 1.060285190268009 0.8935284827681266 0.3080127656634198 1.0 1.0 1.0 0.2183511668733661 5.436360967141595e-05 +Response to ph 4 6 2.268296148927139 0.0233111624949724 1.7621359223300972 5.140776699029126 0.3480088533355521 0.3739523760080299 1.2528504590681426 1.153124661134805 1.2011912824917792 0.2945428652003891 0.0102892388568492 0.0937235599037543 0.0155240337321844 0.0119341177484456 0.0143001062154138 +Lipid translocation 3 5 2.2634428528416604 0.0236084036459822 1.720873786407767 4.390776699029126 0.721199302569061 0.3015554657161993 1.2968412758505727 1.7626690867431634 1.2167340583298332 0.2614747358309583 1.0 1.0 1.0 0.0990342687178565 0.0200033311952484 +Positive regulation of mononuclear cell migration 3 9 2.2579698598237115 0.0239475385850509 2.8762135922330097 9.45873786407767 0.0886382248774921 0.5417098390792167 1.6300328286079158 1.7054300369397768 0.9929662660604948 0.3187573347288022 0.0170809326588952 0.007105321595433 0.0255840399150975 0.0033507773717699 0.0351238878380088 +Regulation of anatomical structure morphogenesis 46 155 2.25654944490453 0.0240362423848392 31.645631067961165 147.98300970873785 -0.1487953535063461 0.7526739502513162 12.401873305874282 15.795483029826496 0.5723443218341211 0.2883943816709233 0.4127700013610399 0.7536619549554409 0.6036415279122508 0.3427929506645131 0.1462309047190061 +Response to hepatocyte growth factor 1 6 2.2521074572382904 0.0243154821674158 1.83252427184466 5.682038834951456 0.22147406836211 0.5067944222688716 1.3469168089334904 1.8521485079710065 1.0288209560233612 0.3181783420506056 0.0058302631141811 0.0023758658868836 0.0088504827764808 0.050241067872642 0.1630814235328921 +Fc receptor mediated stimulatory signaling pathway 1 5 2.251732720674612 0.0243391675931226 1.924574209245742 5.489051094890511 -0.0914444115099735 0.5594495759170853 1.426770297035483 1.8722592165700904 0.9175965835312172 0.3049493789328276 0.1639736616263024 0.1070183553885475 0.1993869387044997 0.1067922158236129 0.3080842130268088 +Regulation of lysosomal lumen ph 4 7 2.245420280500161 0.0247411646785227 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.000190495704273 0.0711332726649859 0.0003602808960722 0.0003774704498572 0.0005289198821125 +Negative regulation of lipid transport 2 5 2.242497982378396 0.0249292055621279 0.924757281553398 2.8276699029126213 0.4342697725224849 0.5270592953997885 0.7768924213117536 0.9887284212744736 1.0762398781228004 0.3374769377151341 1.0 1.0 1.0 0.050241067872642 0.0334620993119388 +Amino acid import across plasma membrane 4 6 2.2423419368721227 0.0249392813236004 2.400485436893204 5.689320388349515 0.4658843139000829 0.3469166214138216 1.544580175870074 0.965714446664715 1.2016267132750456 0.2871391427948346 1.0 1.0 1.0 0.0990342687178565 0.0200033311952484 +Homeostatic process 73 318 2.2397940212280085 0.0251042982085125 61.157766990291265 292.84223300970876 0.0447704154292028 0.710284107974066 17.297703502776844 27.83231450914562 0.9738999187508842 0.3562778454735766 0.0044503799635709 0.163813076611749 0.0066526741545362 2.3278894681544317e-05 3.2360033689787093e-05 +Motor neuron axon guidance 0 5 2.23764674405446 0.0252441007249475 2.3907766990291264 5.361650485436893 -0.2110710241337478 0.4966649478755087 1.4598884046461125 1.264828625014118 0.9818182905966252 0.3026854184981101 0.1171014210767626 1.0 0.1432798584585485 0.3258327648280404 0.5492603500015365 +Cellular copper ion homeostasis 2 6 2.233494236391369 0.0255163699836 1.633495145631068 4.138349514563107 0.8027486766067657 0.3358654651123308 1.1881879887367894 1.18353805365164 1.0950331419070014 0.2903029711159642 0.0962276778844043 0.0619434524836269 0.1180585699575878 0.0385233102424958 0.0225979674873623 +Apoptotic cell clearance 4 10 2.223830125574066 0.0261598757017786 1.4150485436893203 8.16747572815534 0.7343377868729896 0.4133364508748849 1.6160802235364573 1.40166698151907 0.89060803593971 0.2988103853625464 0.14419427418718 0.0042324529563037 0.0155240337321844 0.0012174977382918 0.00223229240551 +Ovulation cycle process 2 6 2.2222085439134185 0.0262692153289409 1.058252427184466 4.62378640776699 0.4440196789748265 0.5217853948759069 1.2073821695183378 1.4997466559550183 0.8645205441432668 0.2919611043934346 0.0004641441761527 1.0 0.0008717411361388 0.0119341177484456 0.0701952648708137 +Antigen processing and presentation of exogenous antigen 2 8 2.2148615324041674 0.0267695701668082 2.0800970873786406 7.682038834951456 0.7846141280949802 0.3912377722563422 1.42818099743969 1.069601013737802 0.957994485343778 0.3040877622263243 0.0158457649983195 0.0065792573185243 0.0237627189197599 0.0220300654060922 0.1188827437046941 +Ph reduction 8 12 2.2120046341520165 0.0269663447359462 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 5.934223435344093e-05 0.1287528218161406 0.0001376480525375 4.683808949698386e-05 4.205073922679249e-06 +Transcytosis 2 9 2.211525971854976 0.0269994353983136 2.6893203883495147 7.381067961165049 -0.0963525316297316 0.5283427390922439 1.9769503149641223 1.1774296611822574 0.947888091156137 0.3079267096508385 0.1032391689436505 0.0020655426456597 0.0077184558590264 0.0442367692127036 0.0277461310389573 +Cardiac septum morphogenesis 2 5 2.2111597918734884 0.0270247736445634 2.3155339805825244 5.975728155339806 -0.0276682686733583 0.5118419399844633 1.791959240258615 1.7021953853726592 1.009048346837495 0.3171630722153564 0.0676342549678683 0.237457799625543 0.0978881295505725 0.3882577215817531 0.5035819637571283 +Genitalia development 1 7 2.2088307862369234 0.027186412834137 0.7305825242718447 5.084951456310679 0.6929022329405563 0.4417126641011115 1.037049890892166 1.004874888397969 0.8649138953774324 0.292043177076853 0.014650958710256 0.0060718409625537 0.0219975904219434 0.1147066696002357 0.32624452618512 +Myoblast fusion 5 7 2.20863430674392 0.0272000871181175 1.9781553398058251 6.395631067961165 0.3395477905067229 0.5371773892028991 1.468771527880447 0.813287909114879 0.850557902252689 0.2997188576440586 1.0 1.0 1.0 0.373917962138579 0.000200465132953 +Regulation of long term synaptic potentiation 3 7 2.2084387016308886 0.0272137064440143 2.191747572815534 6.026699029126213 0.6105178624452509 0.3860292464291884 1.2788913032023987 1.4948993461258857 1.1199694698848182 0.3107967468650517 0.014650958710256 0.0060718409625537 0.0219975904219434 0.0024740226177806 0.0269295467729808 +Artery development 3 11 2.2081106767804104 0.0272365589202903 3.04126213592233 9.516990291262136 -0.3354094123560088 0.4560597544976848 2.0481453507714487 2.380585444414497 1.0494832567265522 0.3117695977494945 0.3737836967212937 0.0348230103466341 0.1132051672598368 0.0578139139832752 0.3326328598090462 +Interleukin 12 production 3 6 2.207135062982122 0.027304624812753 1.9781553398058251 6.199029126213592 -0.0294720344219504 0.5734181289098386 1.233437258645601 1.3289893339064465 0.8511179659964764 0.301023696634852 1.0 1.0 1.0 0.0197332243190265 0.0269295467729808 +Cell activation 25 135 2.2051197899345545 0.0274456897262049 25.703883495145632 129.35679611650485 0.0692955426080309 0.7387037397563144 8.997285699976919 13.941847930447135 0.6883852192819997 0.3033879823523219 0.5238976688533908 0.4285758853426746 0.3247961018067472 0.0497560347978647 0.3312775207816467 +Response to lead ion 1 5 2.201461594214192 0.027703362688279 1.4029126213592231 4.007281553398058 -0.0988607574971427 0.524902218150825 1.0013540648735388 0.670056792513667 0.9589182244853864 0.3025770970380337 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.3258327648280404 0.1807018090276839 +Amyloid beta clearance by transcytosis 0 5 2.1982737140194923 0.0279296064216587 1.7427184466019416 4.62378640776699 -0.1321590834087047 0.5524368465261686 1.3115692773435086 0.7450270295544367 0.8638475235902433 0.2867638222114301 1.0 0.0338360956076009 0.0653907127050202 0.1583736196074974 0.2942334307578267 +Antigen processing and presentation of peptide antigen 7 14 2.1897639475312447 0.0285413606542754 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 0.0283352543336475 0.0119629297909749 0.0420348553288257 1.4200557955176332e-05 0.0001729005795719 +Interleukin 1 production 2 8 2.179563722769525 0.0292898163422534 2.6893203883495147 9.771844660194176 -0.1477319988451844 0.528242332262519 1.6925256947675544 1.7726025776241108 0.934820278084547 0.300752712105114 0.2445961327201016 0.1624541869963563 0.2941077913158182 0.0563589352178582 0.2535314416198171 +Cerebellar purkinje cell layer development 3 7 2.178287099924674 0.0293846689695493 2.191747572815534 6.961165048543689 0.8392766864609098 0.2843914142715297 1.2383946131318218 1.2878998490964535 1.1730456034866912 0.2696789702944095 0.1307520596304716 1.0 0.1596960736798767 0.0698282842903305 0.0097510399506001 +Cytokine production involved in inflammatory response 3 8 2.174537934459406 0.029664759721566 1.6844660194174756 6.915048543689321 0.5526695518877155 0.4572127495678942 1.5208746385948606 1.410799796429201 0.9262620288568464 0.3010153054171438 0.0134972023129384 0.1070183553885475 0.0202898922491691 0.0175758241055335 0.0233101974365333 +Acute inflammatory response 2 5 2.174492809735135 0.0296681448112556 1.4466019417475728 4.689320388349515 0.9285034691739726 0.2315648833934721 0.949993922717463 0.5957637867345709 1.213201626775504 0.2269795845272838 0.014650958710256 0.1114073342812727 0.0219975904219434 0.0197332243190265 0.1083207684216986 +Antigen processing and presentation of endogenous peptide antigen 4 8 2.1702588276654886 0.0299872437774066 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 1.0 1.0 1.0 0.0002821754852333 0.0003671727016274 +Antigen processing and presentation of endogenous antigen 4 8 2.1702588276654886 0.0299872437774066 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 1.0 1.0 1.0 0.0003774704498572 0.0005289198821125 +Negative regulation of mrna 3 end processing 1 7 2.1688691604516137 0.0300926186878531 2.9635922330097086 6.468446601941747 0.2166539590331943 0.6001953854826652 1.905825180895102 1.086758123053347 0.7594435552730779 0.2898575846163733 1.0 1.0 0.0832836732680532 0.0189506401306209 0.0675218785318175 +Bone resorption 3 7 2.168289369710469 0.0301366767312221 1.8592233009708736 7.014563106796117 0.2083023295273233 0.4386245488984792 1.545298971494424 0.9242060635806713 1.1410360097988987 0.3142453330896848 0.0170809326588952 0.007105321595433 0.0255840399150975 0.0244664942800011 0.0351238878380088 +Positive regulation of glucose import 2 6 2.1680681521215908 0.0301535015628373 1.5533980582524272 4.643203883495145 0.3596176533471029 0.4856975847415271 1.101439088125439 1.2272700097688862 0.9775890060329886 0.3007705393502626 1.0 1.0 1.0 0.0768284795296569 0.0618109910728358 +Maintenance of blood brain barrier 2 6 2.167985327822342 0.0301598028893155 2.650485436893204 6.808252427184466 -0.077880046151196 0.5477325470988852 1.6719196446993512 1.121125411676901 0.9179824405634358 0.3056830481168421 1.0 1.0 1.0 0.1227655047468798 0.1188827437046941 +Golgi to vacuole transport 2 7 2.159071308164571 0.030844635196541 2.1990291262135924 6.684466019417476 -0.1721194290132491 0.5176214279350251 1.5293881729690744 1.066912547853689 0.9858058434549826 0.3169991723772594 0.1307520596304716 0.0847528009868792 0.0126574737404708 0.0698282842903305 0.0539281835546241 +Semaphorin plexin signaling pathway 0 5 2.1551955976924924 0.0311465312727312 1.5922330097087378 6.449029126213592 0.1285785339825718 0.5018629999830444 1.5339959443743525 1.3200559083210872 0.9351172255595104 0.2742371710353924 0.1769084608978667 0.1157751708195439 0.2147385524083838 0.4600796867443816 0.7122509845733965 +Vitamin transmembrane transport 2 7 2.151771656482459 0.0314153432390609 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.1101969479300293 0.0711332726649859 0.1349531130589082 0.005208827916976 0.0048822579474643 +Lipoprotein catabolic process 1 5 2.151040917840976 0.0314729701741858 1.529126213592233 5.211165048543689 0.7074087979902727 0.279320898549559 1.1111204061152251 0.9407555329409328 1.2623530327786678 0.2599848817817885 0.1101969479300293 1.0 0.1349531130589082 0.050241067872642 0.1630814235328921 +Response to nitrogen compound 46 242 2.148521142503385 0.0316723786556174 45.4247572815534 232.75 0.042710442463939 0.8941347715182684 14.069752334932211 21.513669734308305 0.3781317508190892 0.2101268567750735 0.1410986026832552 0.1044028796777734 0.1872482020620901 0.0544419780890649 0.0903051235359975 +Vascular associated smooth muscle cell migration 4 6 2.147984822674759 0.0317149611794485 1.3737864077669903 3.512135922330097 -0.0246659690817684 0.5584760991271815 1.0315848082025445 0.907010613702938 0.9547330074886876 0.3149489104993331 0.0962276778844043 1.0 0.1180585699575878 0.0385233102424958 0.0027630263410089 +Regulation of multicellular organismal development 46 193 2.1467293689503943 0.0318148332383272 35.679611650485434 176.2742718446602 -0.2355802429200441 0.734226959967903 14.301003829409888 19.35087409791312 0.5211602889673093 0.2778826243432628 0.15153048620014 0.4254629522107154 0.3238281526354831 0.1475302950035206 0.0805798050713509 +Positive regulation of mitochondrial membrane potential 1 5 2.1441039491740423 0.0320245587185781 1.364077669902913 3.8592233009708736 0.466365083303736 0.5595064518974401 0.9621329832525916 0.6999218948386602 0.7924469360841313 0.3081726674594855 1.0 1.0 1.0 0.014977467250991 0.0542215392640632 +Neuromuscular process controlling balance 4 12 2.142370521089097 0.0321636781040834 3.8810679611650487 11.723300970873789 0.1269749302219408 0.3318237886495486 1.6788029789058698 1.2889149409291965 1.4027465363164735 0.2954189115293261 1.156195301416772e-06 0.0002365528693072 3.3768958612978955e-06 0.0002915955446555 0.0010205277760807 +Antigen processing and presentation of peptide antigen via mhc class i 6 12 2.134983036956545 0.0327623957466129 3.5533980582524274 10.33980582524272 0.9522781165124746 0.321717188118692 1.7458864571217907 1.7766194475253527 0.972074824811495 0.2764762653101907 0.1574312068776012 0.1026081339138497 0.191600110602388 1.048571189794848e-05 5.493155547881244e-05 +Syncytium formation 5 8 2.129017586083811 0.0332528054437197 2.157766990291262 7.036407766990291 0.4033414225617926 0.536077368027232 1.4867906611148458 1.1453302015660312 0.8381553292924435 0.3029132102629827 1.0 1.0 1.0 0.4732445906533414 0.0012730265791845 +Chaperone mediated autophagy 2 9 2.1265409792170207 0.033458240902304 1.9951456310679612 7.677184466019417 0.1640312365213783 0.4319192752719011 1.747390767216852 1.0240618889403386 1.1129367798588556 0.3015487526292348 0.0962276778844043 1.0 0.0066572828402184 0.0033939033653995 0.0225979674873623 +Positive regulation of cell differentiation 28 122 2.1255581231476306 0.0335400696099845 29.635922330097088 119.78398058252426 -0.3041540147273125 0.652847591220036 13.280340637584493 12.127335554445104 0.6738509424320481 0.3036272393631926 0.4701088596321344 0.6592246582244335 0.6408140036739942 0.1413738101511353 0.2160965653109017 +Glycoside metabolic process 4 10 2.124211392109643 0.0336524710532732 3.283980582524272 8.611650485436893 0.5062828222010527 0.3204164092287125 1.4990079825210394 0.6824144700308834 1.298018080705215 0.2868097664691992 0.000190495704273 4.844157765872774e-05 0.0003602808960722 2.0114332489481176e-05 0.0005289198821125 +Regulation of neutrophil chemotaxis 1 7 2.121972324992188 0.0338400621267716 2.9684466019417477 6.728155339805825 0.2519140072217251 0.62378456666035 2.031660690117817 0.891645960882942 0.7135555684185358 0.2871106870099976 0.0891620654695603 1.0 0.1094892401774078 0.0331187861076589 0.1125747569923622 +Regulation of glycoprotein metabolic process 2 11 2.117731653734689 0.0341978004891927 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.1959410376589995 0.1287528218161406 0.2372212797486779 0.029757296929711 0.1526461610854137 +Regulation of proteolysis 19 169 2.1165012494592825 0.0343021990516463 35.237864077669904 159.80825242718447 0.1220464510244959 0.7820148614159474 13.043494204733015 14.183082697709512 0.6674346727992686 0.3042969325537883 0.0187886951027093 0.0187221782124194 0.0234532948585938 0.0095700049905547 0.1101184466570686 +Eye photoreceptor cell differentiation 2 5 2.11372297263132 0.0345389352210656 1.395631067961165 4.368932038834951 0.5347069230760966 0.4323383110298385 0.9834950258292608 0.788143834664171 0.9864809518799904 0.2899129502628464 0.1239529915803282 1.0 0.1515272625734178 0.0630532374058985 0.0465653262864464 +Tissue regeneration 2 6 2.113360269260769 0.0345699438312503 2.237864077669903 5.939320388349515 0.0058255705017962 0.5074833040137664 1.523831177412142 1.1756871670759337 0.9998757083281912 0.3118745730683118 1.0 1.0 1.0 0.2179356607727124 0.2535314416198171 +Glycosylceramide metabolic process 3 6 2.109694727961338 0.0348846589021196 1.6019417475728157 3.6237864077669903 0.6319353949505291 0.2725232617281626 0.981279191145714 1.1370705133968653 1.4246462713481394 0.2720167900467778 0.0820419193359714 0.0526645480715484 0.1008375048293403 9.854683287521486e-05 0.0013781701696679 +Regulation of fatty acid oxidation 2 6 2.108713320150096 0.0349693343815862 1.3907766990291262 4.628640776699029 -0.3768732399728296 0.3674213430467569 0.9191661367945844 1.365474097789965 1.149614350041312 0.2543174722581693 0.1307520596304716 0.0847528009868792 0.1596960736798767 0.0088528623379573 0.0539281835546241 +Liposaccharide metabolic process 12 23 2.1080506306693345 0.0350266101680121 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 5.243657567509587e-06 0.0001786553420583 1.2296564334831526e-06 9.091414863991687e-10 6.842984710025082e-08 +Inorganic anion transmembrane transport 4 8 2.107908206106595 0.0350389302733884 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.2021881519424126 1.0 0.2445730022705269 0.510851629797044 0.0119362160344991 +Positive regulation of protein localization to cell surface 2 6 2.107033262944573 0.0351146963940107 1.480582524271845 4.186893203883495 0.2313167703611407 0.5555336561177834 1.122199491846447 1.4130195782084602 0.9132104900737312 0.3110903277369168 1.0 1.0 1.0 0.0233125205204954 0.0105668672564949 +Negative regulation of molecular function 43 221 2.098605107168588 0.0358517257848856 45.34708737864078 211.33009708737865 -0.2608529517701524 0.7166496596769991 16.233233808029485 21.995978604005224 0.6260357890333693 0.3038168200621631 0.2261601775081599 0.0353461531049698 0.2724911197777404 0.1487982249499112 0.1129194748255005 +Embryonic digit morphogenesis 1 7 2.097843206400301 0.035918998366315 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 0.0436242991079327 0.1908924307699622 0.0640285846884502 0.2813288077075832 0.6247651003553614 +Ion transport 51 221 2.0935652400606126 0.0362987267280705 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 0.0552653123816972 0.0335777040891331 0.0821292627403398 0.1381187571404975 0.0022175395378229 +Negative regulation of lipid localization 2 6 2.0934397054391294 0.0363099211312445 1.2912621359223302 3.929611650485437 0.2770565950748809 0.5468634337387551 0.9767299113031568 1.11363868077603 0.9153497400592624 0.3010316620657979 1.0 1.0 1.0 0.1147066696002357 0.1083207684216986 +Central nervous system neuron axonogenesis 0 6 2.091848240281991 0.0364520934677037 2.512135922330097 5.116504854368932 -0.1747107898249933 0.5207310166961018 1.5895130538990272 0.9009269323064308 0.8995390435569972 0.2936438010084007 0.1574312068776012 1.0 0.191600110602388 0.4185863086244521 0.6658017842410733 +Response to l glutamate 2 6 2.0918262906538234 0.0364540576328129 1.029126213592233 4.37378640776699 1.2967513270419406 0.258405010407401 0.7465949978845596 0.5879801140961596 0.7687098467942305 0.2572187080379352 1.0 1.0 1.0 0.1988473022417859 0.0076703518288617 +Fc receptor signaling pathway 1 5 2.0897446312516275 0.0366407454842299 2.434567901234568 6.303703703703704 -0.1887920783238133 0.513488227334657 1.740949116326016 2.1335905194767566 0.9996183728939608 0.3078132725522039 0.2327120363884492 0.1541506060207377 0.2802926639431586 0.2000228109389489 0.4967295098899271 +Positive regulation of chemokine production 0 8 2.087880583374183 0.0368086080796365 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 0.1639736616263024 0.1070183553885475 0.1993869387044997 0.4327587673805496 0.6820616738325311 +Regulation of cell projection organization 41 126 2.0847325783547657 0.0370935817128805 24.968446601941743 116.3883495145631 0.1438396928004151 0.7137836838737817 11.111590839524858 13.66252973043869 0.7745745022937258 0.3212717801361091 0.4511360019615181 0.6457946290350247 0.6214228321180726 0.5162367412404542 0.0912449314618602 +Plasminogen activation 0 5 2.083529340649407 0.0372030001287653 0.9029126213592232 4.648058252427185 0.4016821115809662 0.4798000612819785 1.2028652129479482 0.5702334018005126 0.9266179387294012 0.2825904528351491 0.0820419193359714 0.0526645480715484 0.1008375048293403 0.2373820829012167 0.4217257773445009 +Positive regulation of cellular component biogenesis 34 118 2.080612654419462 0.0374693746806571 30.02912621359223 113.6868932038835 -0.2821691302797726 0.639072582262895 12.858419711960115 11.897275655280112 0.739470936212581 0.3059892639937149 0.7499992718979502 0.5053132275372465 0.8470983536864666 0.3241335672569531 0.072372499510893 +Astrocyte differentiation 3 11 2.080536811407463 0.037476322852709 3.094660194174758 11.42233009708738 0.0584209125016935 0.5547337588992057 2.207285076469246 1.943694412377063 0.913626470884625 0.299483644308788 0.2562984571775746 0.0148056693212618 0.0513963234576887 0.013184387389335 0.0353817250131281 +Ceramide transport 1 5 2.079417678089737 0.0375789770459871 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0962276778844043 0.0619434524836269 0.1180585699575878 0.2740704871267072 0.1289341732663725 +Diol metabolic process 4 8 2.0769319241977766 0.0378078427804735 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.1171014210767626 1.0 0.1432798584585485 0.000493734331549 0.0007388687073799 +Diol biosynthetic process 4 8 2.0769319241977766 0.0378078427804735 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0962276778844043 1.0 0.1180585699575878 0.0002054625318554 0.0002457979454447 +Modulation of excitatory postsynaptic potential 1 5 2.075503446070408 0.0379398998139093 0.8616504854368932 4.184466019417476 0.8716049128546732 0.3904030169730884 0.8964791942932838 0.8154761884284932 0.955782621454512 0.3079648786148587 0.1239529915803282 0.0802348466038066 0.1515272625734178 0.0630532374058985 0.1985866733922443 +Extracellular matrix disassembly 2 6 2.072496631015023 0.0382191501069977 2.2063106796116503 7.216019417475728 0.1063496442815648 0.573569007700299 1.7949927605074891 1.549956366317142 0.8506235788930436 0.3075454496370982 1.0 0.1201219647894398 0.2223047329091382 0.4732445906533414 0.1298078118605267 +Positive regulation of interleukin 1 production 1 7 2.07183794863841 0.0382805563500816 2.075242718446602 7.565533980582524 -0.0360261344876269 0.5208225219870025 1.4850937956453978 1.245604487832095 0.9358677711957404 0.2968726813360106 0.14419427418718 0.0937235599037543 0.1758008751515455 0.0840389641709933 0.2531867173469597 +Muscle structure development 28 98 2.069404224706368 0.0385081704070331 20.79126213592233 92.5509708737864 0.0014536259301341 0.6464566495683531 7.910305516126998 9.341411300056407 0.7931862105947302 0.3124032629019018 0.5071464627064682 0.5115559036659918 0.6534419385640651 0.0440210947291945 0.0311375242026476 +Response to oxygen containing compound 31 274 2.0660700174108437 0.0388218688028076 48.78155339805825 273.7669902912621 -0.0414966249474367 0.8246448164404616 15.813256375541531 28.130056441601266 0.4928006342114703 0.2648986811695466 0.1418524919745603 0.0631080454808775 0.1377324440871268 0.0859854649545863 0.4444723331499313 +Behavior 26 80 2.0618815154838126 0.0392190177776448 16.990291262135923 75.04126213592232 0.2909440827671418 0.5405324846032677 5.526186812971979 8.403983472903677 1.109438409605415 0.3578193814797769 4.131108737315556e-05 0.0427990140503725 0.0002583499753073 0.0001030618395794 0.0014466559588784 +Positive regulation of wound healing 3 6 2.060152685080666 0.0393839465502143 2.478155339805826 7.220873786407767 0.0474236986481046 0.5930516923552631 1.7423921997676906 1.1626264264032105 0.7925254710040153 0.2833719558343438 1.0 1.0 0.2223047329091382 0.1309570889500886 0.1298078118605267 +Response to hormone 23 183 2.0595682475341315 0.0394398343468347 31.8495145631068 178.40533980582524 0.0990725127189358 0.7976167729201766 12.021488638464843 17.948909982077637 0.5617241006022542 0.2868912739823467 0.0152108761206114 0.0981417691512927 0.0517479490474226 0.020486851178614 0.1381934425889141 +Transepithelial transport 2 5 2.05925775852259 0.0394695527417956 1.6553398058252426 4.774271844660194 0.6732735902855568 0.3468688130957016 1.1752486335033188 1.0771313051019258 1.1029852758785914 0.2818815040837556 1.0 1.0 1.0 0.3422564852890665 0.0465653262864464 +Maternal placenta development 1 6 2.056922966792548 0.0396936363836191 1.4733009708737863 4.604368932038835 0.272983125836839 0.389685533839971 0.9663090505946808 0.948314979731078 1.207690762449098 0.3027145891958461 0.1508382062193919 0.0981765691424607 0.1837383274168749 0.0914454637274335 0.2715157705871365 +Ovulation cycle 4 10 2.0495214684370024 0.0404111507636004 1.7718446601941749 7.815533980582524 0.1981699648128903 0.5986642482329061 1.5830974600770968 1.6085184210885628 0.7344114925742942 0.2722557540618303 0.0012756447222728 1.0 0.0023694947377154 0.0044180066438726 0.010278445998416 +Cytokine production 25 97 2.0492159625878767 0.0404410018584708 18.97087378640777 96.13106796116504 0.0824735848580317 0.7508975178485808 7.48909409104055 11.178920255675855 0.680456448776925 0.3062861740716413 0.2526331801471112 0.4846873920497683 0.3919723151155029 0.0307957158068277 0.0813757518622354 +Glycoprotein metabolic process 22 70 2.048702664287975 0.0404911985292757 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0980241282474227 0.6748528810231245 0.0060138761514709 5.884663824198091e-07 0.0006197995216803 +Positive regulation of jnk cascade 1 5 2.046078335974157 0.0407486640716436 1.8228155339805825 6.058252427184466 0.2557451111653213 0.5101728122759089 1.347476546601903 1.9499825377283675 0.9376553140842416 0.3055032216909335 0.3333506279945079 0.2260688267312995 0.3955810682553247 0.3620385235624148 0.7261148082901132 +Feeding behavior 1 7 2.0401984735280028 0.0413305617354073 1.9587378640776696 6.907766990291262 -0.0082534382830792 0.5361961276161673 1.489688297110135 1.4652074521190883 0.9006411552093863 0.2902722337366559 0.1574312068776012 0.1026081339138497 0.191600110602388 0.0990342687178565 0.2898287915273368 +Cellular response to camp 0 5 2.0396054443127576 0.0413896393663262 1.6019417475728157 5.065533980582524 -0.1953998899771133 0.4214681310513395 1.2034723695122669 0.805368188314036 1.1508648793217675 0.2996934524264009 0.1833015620265946 0.1201219647894398 0.2223047329091382 0.4732445906533414 0.7262550906181415 +Animal organ formation 0 6 2.0393745872065843 0.0414126567058286 2.470873786407767 5.121359223300971 -0.4302699174498804 0.5101876841522336 1.5708590852216906 1.0882559740857742 0.8044872695352823 0.2841640869805038 0.2445961327201016 0.1624541869963563 0.2941077913158182 0.5885248237912099 0.8338318138494164 +Actin filament based process 54 183 2.03904778178529 0.041445258994345 49.89320388349515 174.7597087378641 -0.5360798932414633 0.5895108719513233 18.685003914597623 19.54700652255573 0.9027180043901316 0.343560125073564 0.9290659212454754 0.9359640799555292 0.9008158294514432 0.1731597783843789 0.1984492193795676 +Positive regulation of response to wounding 5 9 2.035868716992652 0.041763539872478 2.8470873786407767 8.618932038834952 -0.1692263977244053 0.588106001668378 1.829747784130376 1.4271741463202623 0.7907543117074023 0.2924174419065002 1.0 1.0 0.2802926639431586 0.2000228109389489 0.0229507437408614 +Photoreceptor cell differentiation 2 6 2.0264072024987256 0.0427230734824477 1.6067961165048543 5.351941747572815 0.3634994200685389 0.4882587847211598 1.1969834363018708 0.7695170068238394 0.8896524383109589 0.2880940406319036 0.1833015620265946 1.0 0.2223047329091382 0.1309570889500886 0.1298078118605267 +Prostate gland development 1 6 2.026206885597837 0.0427435883352584 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.2145389621958136 0.141543756104335 0.2590666885683055 0.1735315682069146 0.4482773855235765 +Cellular homeostasis 26 155 2.0240151335920795 0.0429685946512929 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.001507766927104 0.343850016023122 0.0023895482381491 0.0291372306083628 0.0083266503757647 +Regulation of modification of synaptic structure 3 5 2.0186872976451142 0.0435197310630159 0.9368932038834952 4.138349514563107 0.8230686478854867 0.397984306488242 1.0338438306942168 0.6330579155507905 0.924823257495869 0.3057119359597413 1.0 1.0 1.0 0.2183511668733661 0.3921885014959403 +Positive regulation of developmental process 45 193 2.015883964622662 0.0438121107767632 40.20631067961165 189.05339805825244 -0.2513718418346751 0.7282362213519086 15.029377671248788 19.21169908303489 0.5253739547396956 0.2807052908071442 0.4342064525670267 0.4310806025167489 0.6463121065477412 0.2998209288316549 0.1189683643141138 +Macrophage differentiation 1 5 2.014175889932956 0.0439910700611063 1.6286407766990292 6.334951456310679 0.3401646730548612 0.4969679958563032 1.468258031702074 1.6603432057108871 0.9413197774531912 0.3033822894414889 0.14419427418718 0.0937235599037543 0.1758008751515455 0.0840389641709933 0.2531867173469597 +Regulation of neutrophil migration 1 8 2.010948948491839 0.0443308493547893 3.1529126213592233 7.502427184466019 0.2321960276587156 0.6219840394762427 2.11063333386803 1.0084564442938049 0.7154192886067163 0.2848639012149129 0.1239529915803282 1.0 0.1515272625734178 0.0630532374058985 0.1985866733922443 +Cerebellar cortex development 5 13 2.010623980336502 0.0443651891451954 3.2014563106796117 12.951456310679612 0.4913835354280507 0.4216383686135529 1.7737836843231067 1.855867843348426 1.0191189701346923 0.2901119129344551 0.0299039798790489 0.1583124314184509 0.0443091130960601 0.0525727870350727 0.0062013164624522 +Microtubule anchoring at microtubule organizing center 4 6 2.009042114730149 0.0445326676004687 2.04126213592233 4.679611650485437 0.4532533189811437 0.4885376954843067 1.3185555347709286 1.3381162838073826 0.9568482314374216 0.3123194621401961 1.0 1.0 1.0 0.0331187861076589 0.018020673376298 +Macrophage activation 1 6 2.006425808995013 0.0448108369941731 2.2135922330097086 6.866504854368932 -0.063381422560026 0.4721182263981376 1.4457872208921387 1.8783757746913443 1.04840992449182 0.2953484668101589 0.0331425305019486 0.1665759675679584 0.048990890514732 0.2269450626655096 0.5423832826720252 +T cell activation involved in immune response 2 7 2.005098638368618 0.0449525030299444 2.4611650485436893 7.104368932038835 -0.1214241996365502 0.5735358947720457 1.6238353860870542 0.9197299834896802 0.8380275777451308 0.2957393741365736 1.0 1.0 1.0 0.2450354162713742 0.2936288791787133 +Muscle cell cellular homeostasis 1 7 2.003548807671484 0.0451184143007603 2.0800970873786406 5.550970873786408 -0.3898571923856794 0.4513538970211284 1.417947371327862 0.8948743086477996 1.0863214598084368 0.3248014320258359 0.0962276778844043 1.0 0.0066572828402184 0.0385233102424958 0.1289341732663725 +Lytic vacuole organization 9 27 1.997196187671034 0.0458038750473313 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 6.779156539649845e-10 0.0002038634408731 4.7558782704820654e-09 1.6894394896564589e-07 4.5074720456821366e-06 +Bone remodeling 3 8 1.9970810304937283 0.0458163812569623 2.012135922330097 8.191747572815533 0.5468180618257266 0.3931395839581789 1.401229799996741 1.3580503781098845 1.0682234655932243 0.2933332619823408 0.0382441349097089 0.0163255968864409 0.0563311776114605 0.072741111398958 0.1274755097437061 +Regulation of immune response 22 120 1.99495195608632 0.0460481200635978 25.00242718446602 119.80339805825244 0.248728055937711 0.7234553499352745 8.655908467072013 12.491655004997526 0.7490545850270482 0.335364410227988 0.1857763313831909 0.3004252062192808 0.0820247002855072 0.0545048103588134 0.040782884105911 +Cellular response to exogenous dsrna 4 8 1.993519714479917 0.046204566966101 2.0024271844660193 6.310679611650485 0.5972141116779991 0.4087076192050926 1.2570167843566007 1.13871948363056 0.9497773470751724 0.2837402345544956 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.0565188023636715 0.0007388687073799 +Regulation of amyloid beta clearance 0 5 1.98729392866154 0.0468898340886267 1.1771844660194175 4.669902912621359 0.8976798268240034 0.3552262661555679 1.056723198112258 1.1917055536064145 0.9128228527254058 0.2874114892997187 1.0 0.0479914252810258 0.0921025797166938 0.2183511668733661 0.3921885014959403 +Positive regulation of neural precursor cell proliferation 1 6 1.9857274838481571 0.0470635915516313 1.5970873786407769 5.592233009708738 0.2683284691148795 0.577938943371239 1.3874581292154866 0.9495721387432076 0.7974282394416227 0.2938294518228415 0.1769084608978667 0.1157751708195439 0.2147385524083838 0.4600796867443816 0.3442759855295882 +Cardiac muscle cell proliferation 3 5 1.9842332339100544 0.0472298452715269 1.6310679611650485 4.550970873786408 0.0655294148350886 0.5551169747184266 1.172005925149341 1.1782099426904258 0.8784816860285459 0.2869723239423962 1.0 1.0 1.0 0.2000228109389489 0.0807266025333323 +Viral process 23 144 1.9818596781126168 0.0474949479345494 33.351941747572816 134.23300970873785 -0.425096328430862 0.6165060125927894 14.7574210759245 10.769837315206866 0.7119897372973428 0.312063278943757 0.1997738209393428 0.0576683087237199 0.0244838938649564 0.0302254782622279 0.0102631539101502 +Copper ion homeostasis 2 7 1.9768219461497736 0.0480617600937118 1.6771844660194175 4.669902912621359 0.4484316971142749 0.3058603694529516 1.2128614304476144 1.4202990900289796 1.3716690980071935 0.284002300922153 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.0565188023636715 0.0397387250697101 +Regulation of mononuclear cell migration 5 16 1.9753180246625448 0.0482320690075046 4.548543689320389 16.800970873786408 -0.0451470857329185 0.6235913245378032 2.5976226650972936 2.65933034660148 0.8401157368959713 0.2924888202464074 0.0047187528723135 0.0195557545343205 0.0085749794431607 0.000633861319384 0.0048940429574069 +Establishment of epithelial cell apical basal polarity 3 5 1.972816897341645 0.0485164273095026 3.004854368932039 5.83252427184466 -0.2357394747607657 0.5153496407044241 1.6894807980977786 0.8294403522584168 0.932307207812416 0.3011334666879531 1.0 1.0 1.0 1.0 1.0 +Regulation of lipase activity 3 13 1.9710819164894928 0.0487145068033165 3.262135922330097 11.20873786407767 0.5080857493577803 0.3640362286084045 2.107366483573331 1.390020380944142 1.1722840995258883 0.3007278087276755 0.0382441349097089 0.0163255968864409 0.0065760397653667 0.0157211013123339 0.1274755097437061 +Striated muscle cell proliferation 3 6 1.9639591026626708 0.0495348348897639 2.033980582524272 5.822815533980583 -0.0159301290626847 0.5837784679093959 1.449409213294895 1.3220181082699465 0.8162018369604351 0.2904893030560816 1.0 1.0 1.0 0.2722557910873528 0.1451121707049519 +Positive regulation of fat cell differentiation 2 7 1.9616189923740384 0.0498068594112703 2.3179611650485437 6.0 -0.0556739123770783 0.6178026402837533 1.501897737539353 1.384729478329735 0.7804698584000491 0.2945970482311898 0.2562984571775746 1.0 0.3076603852203092 0.2359805031570881 0.2801972283088816 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..83a3d43b7933bc6acbd7011e6b4bc12177d6db87 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 6510, + "title": "Average number of proteins per term", + "value": 19.98509984639017 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4e668bfe43cb28c85000250334d91fae31a28ca4 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f7731c0a8c8a76fe9397038eeb753de8c828c2ae --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2277 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endocytosis 0.6146029783608966 4.647852544574514 3.354085331030987e-06 0.0215984712628089 0.0218350955050182 127 O15126,P05556,Q99523,Q9UQ16,O15118,Q9NVZ3,P05067,P98164,Q06481,Q9H223,Q08431,P11717,P02786,Q07954,Q5KU26,Q14108,Q8WTV0,Q9UBG0,P20645,P50897,Q08380,Q9Y6I3,O60784,P51790,O15260,Q5JRA6,Q5VW38,Q9H4M9,P06756,P46934,O75955,O00560,Q6UWE0 33 +Carbohydrate metabolic process 0.5594575562769343 4.239178963518818 2.2433876491367855e-05 0.1358821976466249 0.0730222679794056 152 P08195,Q9UBX3,P17900,P05067,P16278,Q16706,Q9NRB3,Q92520,Q01459,P04066,O60512,P06280,Q86SF2,P06865,Q14108,P08236,Q9BTY2,Q9HAT2,P10253,Q8NCH0,Q7LGA3,P31751,Q8NBZ7,P07686,Q9NX62,P15291,O43505,Q11206,O00462,Q99519,Q9BYT8,Q93063,O00754,P31749,Q13572,P40763 36 +Vesicle mediated transport 0.4332848318451894 3.8717568971402874 0.0001080536929365 0.5051336475081261 0.1292597233206925 385 Q99523,P05067,O75503,P98164,Q06481,Q08431,P11717,P02786,Q07954,Q5KU26,Q14108,Q8NBN3,Q9UBG0,P50897,Q08380,Q15904,P51790,P11279,Q7L0J3,Q5VW38,Q9NQ11,Q9BRG1,Q9BRK5,Q08722,Q8TD16,O15118,Q13190,O43752,Q9Y6B6,Q8WTV0,Q92544,P04083,P31751,O43731,O15260,O15400,O00560,Q9UN37,Q6UWE0,Q92572,O60645,Q13277,Q9UQ16,Q9NVZ3,Q5SQN1,Q9H223,P08069,P20645,P84085,Q9Y6I3,O60784,Q9Y282,O95772,Q86Y82,Q5JRA6,Q9H4M9,P06756,P46934,P19022,O75955,Q9UHY1,Q4J6C6,O15126,P05556,Q8TAG9,Q9C0C9,Q9UJU6,Q969X5,O15027,Q12907,Q9Y3E7,Q92783,P56545,O60333,Q14203,P41440,Q99829,P11234 78 +Neuron development 0.4977635381535428 3.866637464364872 0.0001103462765972 0.5124653418463754 0.1292597233206925 195 Q15375,P05556,Q13277,Q9UQ16,P04062,P05067,Q13641,Q04656,O75503,P98164,P42892,Q06481,Q96N67,Q9UJU6,P08069,Q92859,P10586,Q14108,O43464,Q14444,P54802,P50897,O94813,Q15555,P23229,Q13555,Q9UPY3,Q9NV96,Q32P28,A0MZ66,O00264,Q86X55,P61160,P00374,Q96G23,P39880,P41440,Q9UBB6,Q16739,Q9H4M9,Q99829,P46934,P19022,O75955,P31749,Q9NUM4,O14949,Q9UQB8 48 +Proteolysis 0.429782798720345 3.8195585972648898 0.0001336906982545 0.581209560304202 0.1292597233206925 405 P07858,Q10713,Q9UIQ6,P05067,Q15392,O75503,P42892,Q06481,O14773,O75976,Q9H3G5,P02786,Q07954,Q13619,Q96HY6,Q9Y5K6,Q99538,Q9H3S7,Q9HB40,Q13620,P61586,Q9Y4X5,Q92896,P53634,Q8TCT8,O94822,Q92820,P10619,Q96KB5,Q9Y297,Q9Y263,P49721,Q15386,P20618,Q5VTR2,O43567,Q9NWW5,Q8WUX9,Q9UHI8,P42785,Q6P179,Q9NQ11,Q9GZU8,P31749,Q9UBW8,P17655,Q9BRG1,P28074,P28072,Q92542,Q15375,P04062,Q8N6M0,P28070,Q9H3F6,Q9NWU2,P60604,Q9NXR7,Q9BYT8,Q15041,Q9GZP4,O00560,P40763,Q9UN37,Q96ES7,Q9BZK7,Q9H2J4,Q9NZ08,P07384,Q9UJ14,P55786,Q9H1I8,Q8TAD4,Q9UHG3,P46934,P46379,O95831,Q4J6C6,O95816,Q9C0C9,O75787,Q9UNS2,Q9Y3E7,Q9UJX4,O43464,P22695,P19784,Q92783,Q9Y4E8,Q8IXB1,P53350,O43292,P49720,P06493,Q7L5Y9,Q13867,Q9UNN5,Q9UJX5,Q9H8M7,Q99829,Q9BT78,O75915,O75844,Q9H9S5 104 +Neurogenesis 0.4572993187891405 3.812106090162996 0.0001377877087866 0.5922331799843973 0.1292597233206925 286 Q15375,P05556,Q13277,Q9UQ16,Q7L576,P05067,Q9UBS4,Q13641,O75503,P98164,Q96ST3,Q06481,P42892,P04062,Q16706,P08069,Q92859,P10586,Q07954,P21359,Q93074,Q14108,O43464,Q14444,P54802,P50897,Q9GZT8,O94813,Q04656,P04083,P23229,Q15555,Q96N67,P31751,P62258,Q9NV96,Q13144,Q9UJU6,Q13555,Q9UPY3,Q32P28,P07686,A0MZ66,P06493,O00264,Q86X55,P55209,P61160,P00374,Q96G23,P39880,P41440,P58546,Q9UBB6,Q16739,Q9H4M9,Q99829,P46934,P19022,P26583,O75955,Q96N66,P31749,Q04917,Q9NUM4,O14949,Q9UQB8,P40763,Q92542 69 +Biological adhesion 0.4936444892616122 3.689344552078289 0.0002248325541078 0.7686502145723371 0.1292597233206925 179 Q08722,Q96AC1,Q15375,Q13277,Q69YQ0,P05556,P30825,P05067,Q13641,O00192,Q08431,Q92859,Q9P258,P02786,Q9Y624,Q9HBM0,P21359,P10586,Q14574,P15311,Q16539,Q9Y5K6,Q9H3S7,Q8WTV0,P61586,Q92544,O43293,P78310,Q08380,Q14126,Q07021,P04083,Q9BY67,P23229,P43121,P15291,Q14168,Q5JRA6,Q7L5Y9,Q11206,P04439,P41440,Q9UNN5,Q9UDY2,P06756,Q9UM22,P09493,P10644,P19022,O75955,P31749,Q96GC9,Q9UQB8 53 +Response to growth factor 0.5262857411858939 3.5875357099865974 0.0003338180258507 0.8862233710904118 0.1292597233206925 107 P05556,Q99523,Q9C0C9,Q04656,P05067,P98164,Q06481,Q9H223,P08069,Q92859,Q16539,Q99538,O43464,Q92896,P36896,O94813,P04083,P62942,Q9H4M9,P46934,Q93063,P31749,O00560,Q9UQB8,P40763,Q05D32 26 +Neuron differentiation 0.4593362411614787 3.568452584295253 0.0003590958225616 0.9034924115572932 0.1292597233206925 231 Q15375,P05556,Q13277,Q9UQ16,P04062,P05067,Q13641,Q04656,O75503,P98164,P42892,Q06481,Q96N67,Q9UJU6,P08069,Q92859,P10586,Q14108,O43464,Q14444,P54802,P50897,Q9GZT8,O94813,Q15555,P23229,Q13555,Q9UPY3,Q9NV96,Q32P28,A0MZ66,O00264,Q86X55,P61160,P00374,Q96G23,P39880,P41440,P58546,Q9UBB6,Q16739,Q9H4M9,Q99829,P46934,P19022,O75955,P31749,Q9NUM4,O14949,Q9UQB8,P40763 51 +Enzyme linked receptor protein signaling pathway 0.5120315195548157 3.479135988517665 0.0005030332515938 0.962204695263006 0.1292597233206925 126 Q15375,P05556,Q99523,Q9UIQ6,Q9C0C9,P98164,Q06481,P08069,P11717,Q92859,P10586,Q07954,Q16539,Q99538,Q8TBX8,Q92896,P36896,P31751,P62942,P46934,P31749,O00560,Q9UQB8,P40763,Q9BRG1,Q92572,Q05D32 27 +Nervous system process 0.5246072839142938 3.437623089323377 0.0005868439301142 0.9781045275191922 0.1292597233206925 104 P04062,Q99538,P17900,P05067,Q13641,Q14108,P07686,P98164,Q11206,P31749,O14773,Q9NWW5,P50897,Q9UQB8,P53634,P10253,Q92542 17 +Cell morphogenesis 0.4660799915187383 3.307563685516767 0.0009411131054211 0.997822398113871 0.1292597233206925 180 Q96AC1,Q15375,P05556,Q9UQ16,Q7L576,P05067,Q13641,Q04656,Q96N67,P98164,Q96ST3,Q06481,P42892,Q9UJU6,P08069,P38571,Q9Y624,Q92859,Q9P258,P15311,Q16539,P61586,Q14444,O43293,Q07021,O94813,P04083,Q9UPY3,P07686,A0MZ66,O00264,Q16181,P61160,P39880,P41440,Q99829,P06756,P46934,P09493,P19022,O75955,Q04917,Q9NUM4,Q9UQB8,O75844 45 +Organonitrogen compound catabolic process 0.4037246203893718 3.294032586768367 0.0009876104819688 0.9983916093133256 0.1292597233206925 390 Q6YP21,P07858,Q9BZK7,Q9UIQ6,P17900,P04062,P16278,O75503,P98164,P42892,Q13190,O14773,Q9BW91,Q9H2J4,Q9H4H8,Q9NZ08,Q07954,Q01459,P04066,P06280,Q99538,P28070,P06865,P08236,Q8WTV0,P54802,P50897,P15586,P53634,Q9H3F6,P04114,P10619,P13473,P49721,Q9NWU2,Q13510,P07686,Q5VTR2,O43567,Q9NWW5,Q8WUX2,P60604,O43598,Q8NCC3,O00462,Q6P179,Q99519,Q9NQ11,Q9GZU8,P31749,Q9GZP4,Q9NUM4,O00560,P17655,Q9BRG1,Q9UN37,Q6UWE0,P28074,P28072 59 +Protein catabolic process 0.4240112553050355 3.247579810358039 0.0011639101643237 0.9994901877819822 0.1292597233206925 287 P07858,Q9BZK7,O95816,Q9UIQ6,P04062,O75503,P98164,Q13190,O14773,Q9H2J4,Q9H4H8,Q9UNS2,Q07954,Q13619,P15311,Q96HY6,Q9Y5K6,Q99538,P28070,Q9UJX4,Q9Y3E7,O43464,Q9H3S7,Q13620,P19784,Q92783,Q9Y4E8,P50897,Q9Y4X5,P53634,Q9H1I8,Q8IXB1,P53350,Q9H3F6,O94822,P04114,P10619,Q96KB5,P13473,Q9Y297,Q9Y263,P49721,Q9NWU2,Q15386,P49720,P20618,Q5VTR2,O43567,Q9NWW5,P60604,Q7L5Y9,O00462,Q9UHG3,Q9UNN5,Q9NQ11,Q9UJX5,P46934,Q9GZU8,P31749,Q9GZP4,P46379,Q9NUM4,O00560,O75844,P17655,Q9BRG1,Q9UN37,Q6UWE0,P28074,P28072 70 +Cell projection organization 0.4278071239817026 3.239058504650494 0.0011992497141644 0.9995950717738356 0.1292597233206925 269 Q15375,P05556,Q13277,Q9UQ16,Q7L576,P05067,Q13641,P04062,Q04656,P98164,Q96ST3,Q06481,P42892,Q9H223,Q9UJU6,O15511,P08069,Q92859,Q9P258,P10586,P15311,Q9Y5K6,Q99538,Q14108,Q9H3S7,Q13620,Q9P2S5,Q14444,O94813,Q15555,P23229,Q96N67,P61421,Q13555,Q9NV96,Q9UPY3,Q32P28,A0MZ66,O00264,A6NIH7,Q7Z3E5,Q86X55,Q9ULC3,Q16181,P61160,Q14203,P00374,Q96G23,Q9Y496,P41440,P39880,Q9UBB6,Q99829,Q9H4M9,P46934,P09493,P19022,O75955,P31749,Q04917,Q9NUM4,O00560,Q9UQB8,Q9Y3P9 64 +Cell cell adhesion 0.4923318687474911 3.198211803222813 0.0013828267506603 0.9998776264289214 0.1292597233206925 106 Q08722,Q15375,P05556,P30825,O00192,Q9Y624,Q92859,Q9HBM0,P02786,P10586,Q14574,P15311,Q16539,Q9Y5K6,Q9H3S7,P61586,P78310,Q14126,P04083,Q9BY67,P23229,Q14168,Q5JRA6,Q11206,P04439,P41440,Q9UDY2,P06756,P19022,P10644,O75955,P31749,Q96GC9,Q9UQB8 34 +Cell junction organization 0.4841005882870017 3.1402015974945408 0.0016883160882283 0.9999833020780264 0.1292597233206925 126 Q96AC1,Q15375,Q9UQ16,Q7L576,P05067,Q13641,Q9UJU6,O00192,P08069,Q9Y624,Q9P258,P10586,Q16539,Q99538,Q9NQX3,Q9H3S7,P61586,Q14444,O43293,P78310,Q14126,Q15555,P23229,P56545,O00264,Q16352,P61160,Q14203,P41440,Q9UDY2,P46934,P19022,O75955,Q96GC9,O00560,Q9UQB8,Q9BRK5 37 +Cell morphogenesis involved in differentiation 0.4808859246983239 3.096737013764377 0.0019566337484768 0.9999970981540076 0.1292597233206925 125 Q96AC1,Q15375,P05556,Q9UQ16,Q7L576,P05067,Q13641,Q96N67,Q9UJU6,Q96ST3,Q06481,P42892,P08069,Q92859,Q9P258,P61586,Q14444,Q07021,O94813,A0MZ66,O00264,P61160,P39880,P41440,P06756,P46934,P19022,O75955,Q04917,Q9NUM4,Q9UQB8 31 +Circulatory system development 0.4637219473453232 3.086436204834676 0.0020257140977211 0.9999981508302284 0.1292597233206925 161 Q04656,P98164,P42892,Q9H2J4,P08069,Q08431,Q9NZ08,Q07954,P21359,Q16539,Q93074,P19021,P78310,Q14126,P10253,O94813,Q9Y6I3,P04083,P04114,P62942,P43121,P15291,Q8NDZ4,Q13685,Q9UHI8,P42785,Q5JRA6,O96028,P06756,P09493,P10644,P31749,P40763 33 +Macromolecule catabolic process 0.3861332973177679 2.9864780363055456 0.0028221110967248 0.9999999897697412 0.1292597233206925 445 P07858,Q9BZK7,O95816,Q969Z0,Q9UIQ6,P04062,P16278,O75503,P98164,Q13190,O14773,Q9H2J4,O00584,Q9H4H8,Q9UK45,Q9UNS2,P07384,Q07954,Q01459,P04066,Q16539,P28070,Q99538,Q9C0B1,P08236,Q9Y3E7,Q9UJX4,Q9H074,O43464,P19784,Q92783,P54802,Q9Y4E8,P50897,P15586,Q14671,P53634,Q8ND04,Q9H1I8,P10253,Q8IXB1,Q5PRF9,P53350,Q9H3F6,P04114,P10619,Q9UPY3,P13473,P49721,Q9NWU2,P49720,P67809,Q5VTR2,O43567,Q9NWW5,P60604,Q7L5Y9,Q7Z739,O00462,Q9UHG3,Q9UNN5,Q9NQ11,P46934,Q9GZU8,P31749,Q9GZP4,P46379,Q9NUM4,O00560,P17655,Q9BRG1,Q9UN37,Q6UWE0,P28074,P28072,O95831 76 +Immune response 0.4253533889104625 2.965213462621754 0.0030247297069621 0.9999999972750904 0.1292597233206925 217 Q08722,P10321,O15111,Q04656,P05067,Q06481,O00584,P08069,Q9NZ08,P02786,Q07954,Q8ND90,Q5KU26,Q16539,P28070,P01889,O43293,Q14671,P53634,Q07021,Q9NPR9,Q8TCT8,Q9BY67,P04083,P11279,Q9Y487,P62942,O15400,O96028,P61160,P04439,Q7Z739,Q9NUD5,Q6P179,O75955,P46379,O60934,P40763 38 +Positive regulation of signaling 0.4131154217293435 2.9442167965011383 0.0032377311284692 0.9999999993219671 0.1292597233206925 255 Q96AC1,P05556,Q13277,O15111,Q9BZK7,P18615,Q9C0C9,Q7L576,P05067,Q13641,P04062,P98164,P42892,Q06481,O75787,P60866,P08069,Q92859,Q9Y624,P02786,P21359,P30154,O95071,Q99538,O43464,Q9H3S7,Q86SX3,Q9Y4E8,O43293,Q14671,P53634,P36896,Q07021,Q15555,Q9NWU2,P62942,O14777,P56545,O43567,Q14168,Q7Z3E5,Q9NUD5,P41440,Q9UNN5,Q8WVQ1,Q99829,P06756,P46934,P19022,O75955,O00560,Q9UQB8,P40763,O75915,Q92542 55 +Astrocyte activation 0.991147831218648 2.9371013021284593 0.0033129586355289 0.9999999995851756 0.1292597233206925 2 P05067 1 +Positive regulation of protein catabolic process in the vacuole 0.991147831218648 2.9371013021284593 0.0033129586355289 0.9999999995851756 0.1292597233206925 2 P98164 1 +Cellular response to endogenous stimulus 0.418708743413334 2.93003444825712 0.0033892442893677 0.9999999997479656 0.1292597233206925 234 Q96AC1,P05556,P07858,Q99523,Q9P1Z2,O15118,Q7L576,P05067,Q04656,Q9C0C9,P98164,Q96ST3,Q06481,P23634,O00410,P08069,Q92859,Q07954,P15311,O95071,Q96HY6,Q99538,Q8TBX8,P61586,Q9Y4E8,Q92896,O94813,P04083,P04114,P31751,P62942,P42785,Q86X55,P61160,P34896,Q16739,Q9H4M9,P46934,Q93063,P31749,Q15185,Q04917,Q9GZZ9,O95831,O00560,Q9UQB8,P17655,P40763,P29992,O75844,Q92572,Q92542,Q05D32 53 +Tissue development 0.4050264700294584 2.906297580619326 0.0036573344515411 0.999999999956266 0.1292597233206925 286 Q15375,P05556,P07858,Q9BZK7,P07602,Q04656,Q15392,Q8NEY8,P98164,P42892,P51648,O14773,P14649,Q9H4H8,Q9Y624,P21359,Q16539,Q93074,P78310,Q92896,Q14126,P36896,P10253,O94813,P04083,P23229,P60660,Q8TAA9,P31751,Q9UBB9,Q13510,P62942,P67809,Q9NX62,P15291,Q16527,Q8NDZ4,O43598,Q96PZ0,Q9UDY2,P58546,Q16739,P06756,Q9BYT8,P09493,Q93063,P10644,P19022,P31749,O75955,O00560,Q13572,Q8N5W9 53 +Microglial cell activation 0.9834759516081424 2.9059924759417184 0.0036609025190548 0.9999999999572736 0.1292597233206925 2 P05067 1 +Chemical homeostasis 0.4287390050266613 2.884593287461812 0.0039191962287905 0.9999999999920997 0.1292597233206925 200 O15118,P04062,P05067,Q04656,O75503,Q06481,P08069,Q92859,P02786,Q9Y6B6,Q8WTV0,Q92544,P50897,Q15904,Q93050,P04114,P61421,P51790,P62258,Q9Y487,Q7L0J3,P62942,P07686,P61916,Q9NWW5,Q8TAD4,O15260,P42785,Q9NQ11,Q16739,Q9NWR8,P35670,Q9H4M9,Q93063,P31749,Q9NUM4,Q5BJF2,P40763,Q9BWH2 39 +Developmental growth 0.4651256203228547 2.8760133119205027 0.0040273272682089 0.9999999999961032 0.1292597233206925 107 Q15375,P05556,Q9BZK7,P07602,Q7L576,P05067,Q9UJU6,Q96ST3,P15311,Q16539,Q9C0B1,Q99538,Q93074,O43464,P16989,P11413,Q7Z4V5,O94813,P04083,Q9Y263,A0MZ66,P06493,Q8NDZ4,Q9BRT9,P58546,Q99829,P10644,P43034,P31749,Q15056,O60934,P40763,O75844 33 +Central nervous system development 0.4283806764486035 2.871599773393952 0.0040839983778193 0.9999999999973094 0.1292597233206925 199 Q15375,P05556,P04062,P05067,Q04656,Q96N67,O75503,P98164,Q06481,O14773,P51648,O75787,P08069,Q9UQR1,Q07954,P21359,O15027,Q5KU26,Q93074,O43464,P19784,P68402,P54802,P19021,P50897,P11413,O94813,Q9BY67,Q13144,P61421,P62258,Q16352,P58546,P19022,Q96N66,P46379,O14949,Q9UQB8,P40763,Q9BRK5,Q92542 41 +Animal organ morphogenesis 0.4641650289208162 2.8640355098097463 0.0041828111761788 0.9999999999985896 0.1292597233206925 110 P04062,Q16706,P98164,P07384,P21359,Q16539,Q93074,P54802,P19021,Q92896,P10253,O94813,P23229,Q8TAA9,P62942,Q9NX62,Q9UHI8,O96028,P09493,Q93063,P40763,Q8N5W9 22 +Regulation of glucosylceramidase activity 0.9704927707288268 2.853079151368047 0.0043297835676907 0.9999999999994604 0.1292597233206925 2 Q14108 1 +Ganglioside catabolic process 0.9716563330380888 2.8521679066503607 0.0043422157676993 0.9999999999995026 0.1292597233206925 4 P06865,P17900,P07686 3 +Oligosaccharide catabolic process 0.9719432959243928 2.85111309356104 0.0043566470909617 0.9999999999995474 0.1292597233206925 5 O00462,Q01459,P17900,P07686 4 +Ganglioside metabolic process 0.9719432959243928 2.85111309356104 0.0043566470909617 0.9999999999995474 0.1292597233206925 5 P06865,P17900,Q9NWW5,P07686 4 +Multi organism reproductive process 0.447621408238922 2.8479028493508496 0.0044008356608595 0.9999999999996608 0.1292597233206925 159 P05556,P07858,Q9UIQ6,Q04656,P05067,Q08431,P11717,Q9UQR1,P19784,P68402,P19021,P78310,Q14671,P36896,Q07021,Q9Y6I3,P53350,Q9BY67,P04114,O14777,P07686,P06493,P15291,Q8NB78,Q9UHI8,Q16181,Q7Z739,P41440,P31749,Q9GZP4,P46379,Q15056,Q96GC9,P40763,P17655,Q9Y2W6 36 +Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process 0.9687223369725568 2.8458374891950062 0.0044294794011292 0.9999999999997188 0.1292597233206925 2 Q7LGA3 1 +Regulation of cellular extravasation 0.962525818825611 2.8204418930767683 0.0047957558082738 0.9999999999999744 0.1292597233206925 2 Q11206 1 +Leucine transport 0.9607553850693384 2.8131717544592107 0.00490554413561 0.9999999999999876 0.1292597233206925 2 Q9H2J7 1 +Branched chain amino acid transport 0.9607553850693384 2.8131717544592107 0.00490554413561 0.9999999999999876 0.1292597233206925 2 Q9H2J7 1 +Lipid glycosylation 0.959280023605782 2.807108456028049 0.0049988408352026 0.9999999999999932 0.1292597233206925 2 Q11206 1 +Microglia differentiation 0.9592800236057788 2.807108456028035 0.0049988408352028 0.9999999999999932 0.1292597233206925 2 P05067 1 +Regulation of hydrolase activity 0.4337983190871168 2.802965645249372 0.0050635062751109 0.9999999999999956 0.1292597233206925 176 Q15375,P05556,P07858,Q99523,P07602,Q9C0C9,P05067,Q15392,Q06481,Q13576,Q9Y624,Q07954,P21359,Q8IZ81,Q99538,Q14108,P50897,P04083,P23229,P31751,P62942,Q9NQ11,Q15041,P31749,Q9NUM4,O95831,P40763,Q92542 28 +Dermatan sulfate biosynthetic process 0.9578046621422216 2.8010407442855954 0.0050938087246266 0.9999999999999964 0.1292597233206925 2 Q8NCH0 1 +Dermatan sulfate proteoglycan metabolic process 0.9578046621422216 2.8010407442855954 0.0050938087246266 0.9999999999999964 0.1292597233206925 2 Q8NCH0 1 +Dermatan sulfate metabolic process 0.9578046621422216 2.8010407442855954 0.0050938087246266 0.9999999999999964 0.1292597233206925 2 Q8NCH0 1 +Keratan sulfate metabolic process 0.958960732211398 2.799680036301968 0.0051153282447706 0.9999999999999968 0.1292597233206925 4 O43505,Q11206,P15586 3 +Regulation of cellular component movement 0.4469458749130259 2.7986564306860844 0.0051315706290102 0.9999999999999972 0.1292597233206925 153 Q08722,P05556,Q04656,P05067,Q96N67,Q06481,P08069,Q07954,P21359,Q16539,Q99538,Q8WTV0,O43293,Q14126,P36896,Q07021,O94813,P04083,P23229,P31751,P11279,A0MZ66,P43121,Q5VTR2,Q13685,Q9UHI8,P42785,Q5JRA6,Q11206,Q7Z739,Q96G23,P06756,P09493,P31749,O00560,P40763 36 +Regulation of monocyte chemotaxis 0.9586776554828011 2.798505954851336 0.0051339622773554 0.9999999999999972 0.1292597233206925 4 Q99538 1 +Fucose metabolic process 0.9572679695573928 2.7955139819982713 0.0051817260317954 0.999999999999998 0.1292597233206925 3 P04066 1 +Response to peptide 0.4976636116605984 2.791135677320497 0.0052523450259565 0.9999999999999988 0.1292597233206925 101 P04083,Q99523,P31751,Q99538,P05067,Q8TBX8,P31749,O95251,Q06481,Q9UQB8,P40763,P08069,Q92572,Q07954 14 +Carbohydrate derivative metabolic process 0.3994269385056806 2.789360591044909 0.0052812227793452 0.9999999999999988 0.1292597233206925 282 O15118,P17900,P05067,P04062,P16278,Q04656,Q9NRB3,Q16706,Q9Y287,Q9UMR5,Q99805,Q01459,P04066,O60512,P06280,Q86SF2,P06865,P08236,Q9BTY2,P54802,Q10472,P50897,P15586,Q8NCH0,Q7LGA3,Q8NBZ7,Q9P2E5,P07686,Q9NX62,P15291,Q9NWW5,O43505,O43598,Q11206,O00462,Q99519,Q8WVQ1,Q9UDY2,Q16739,Q93063,O00754,Q10471,P40763,Q92542 44 +Regulation of protein catabolic process in the vacuole 0.9567542586295134 2.7880156866114048 0.0053031975855937 0.9999999999999992 0.1292597233206925 5 P98164,Q9NQ11,Q07954 3 +Regulation of lysosomal protein catabolic process 0.9567542586295134 2.7880156866114048 0.0053031975855937 0.9999999999999992 0.1292597233206925 5 P98164,Q9NQ11,Q07954 3 +Cell morphogenesis involved in neuron differentiation 0.5534887105773841 2.783988892678627 0.0053694872918468 0.9999999999999994 0.1292597233206925 95 Q15375,P05556,Q9UQ16,Q7L576,P05067,Q13641,Q96N67,Q9UJU6,P42892,Q06481,P08069,Q92859,Q14444,O94813,A0MZ66,O00264,P61160,P39880,P41440,P46934,P19022,O75955,Q04917,Q9NUM4,Q9UQB8 25 +Cell part morphogenesis 0.4554532680607022 2.7811564613265034 0.0054165624910764 0.9999999999999996 0.1292597233206925 126 Q15375,P05556,Q9UQ16,Q7L576,P05067,Q13641,Q04656,Q96N67,P98164,P42892,Q06481,Q9UJU6,P08069,Q92859,Q14444,O94813,Q9UPY3,A0MZ66,O00264,P61160,P39880,P41440,Q99829,P46934,P19022,O75955,Q04917,Q9NUM4,Q9UQB8 29 +Cell migration 0.4121040181510643 2.776298299838023 0.0054981737867776 0.9999999999999998 0.1292597233206925 224 Q08722,P05556,P04062,P05067,Q13641,Q04656,Q96N67,Q06481,Q9H4H8,P08069,Q9Y624,Q92859,Q07954,P21359,Q16539,Q99538,Q8WTV0,O43293,P78310,P36896,Q07021,O94813,P04083,P23229,P31751,P62258,P07686,A0MZ66,P43121,P15291,Q5VTR2,Q13685,Q9UHI8,P42785,Q5JRA6,Q11206,Q7Z739,Q96G23,P06756,P09493,P19022,Q96N66,P31749,O00560,P40763 45 +Response to endogenous stimulus 0.398007290303434 2.7754277349088157 0.0055129149449679 0.9999999999999998 0.1292597233206925 285 Q96AC1,P05556,P07858,Q99523,Q9P1Z2,O15118,Q7L576,P05067,P04062,Q15392,P16278,P98164,Q96ST3,Q06481,Q04656,P23634,O00410,P08069,Q92859,Q07954,P15311,O95071,Q96HY6,Q16539,Q99538,Q8TBX8,P61586,Q9Y4E8,P19021,Q92896,O94813,Q9C0C9,P04083,Q13144,P04114,P31751,P62942,P42785,Q86X55,Q5JRA6,P61160,P34896,Q16739,Q9H4M9,Q99829,P46934,P26583,Q93063,P31749,Q15185,Q04917,Q9GZZ9,O95831,O00560,Q96T76,Q9UQB8,P17655,P40763,P29992,O75844,Q92572,Q92542,Q05D32 63 +Glycolipid catabolic process 0.9525820924595838 2.766993420927579 0.005657589688405 1.0 0.1292597233206925 8 Q99519,P04066,P06280,P06865,P17900,P07686 6 +Cellular component morphogenesis 0.4484883883376097 2.7658031796785902 0.0056782794828746 1.0 0.1292597233206925 142 Q15375,P05556,Q9UQ16,Q7L576,P05067,Q13641,Q04656,Q96N67,P98164,P42892,Q06481,Q9UJU6,P08069,Q92859,Q14444,O94813,Q9UPY3,A0MZ66,Q16527,O00264,P61160,P39880,P41440,Q99829,P46934,P09493,P10644,P19022,O75955,Q04917,Q9NUM4,Q9UQB8 32 +Ceramide catabolic process 0.9521916136229156 2.765340247852905 0.0056863449776103 1.0 0.1292597233206925 8 Q99519,P06280,P06865,P17900,Q13510,P07686 6 +Glycosaminoglycan catabolic process 0.9509746012994656 2.763881748937243 0.0057118234861841 1.0 0.1292597233206925 5 P15586,P54802,P04066,P16278 4 +Aminoglycan catabolic process 0.9512555391432792 2.76291416402294 0.0057287829830003 1.0 0.1292597233206925 6 Q01459,P04066,P16278,P54802,P15586 5 +Vitamin d metabolic process 0.9466450771355148 2.748447991579656 0.005987813351505 1.0 0.1292597233206925 4 Q99538,P98164 2 +Positive regulation of trophoblast cell migration 0.9448214812629092 2.7474539255838133 0.0060059946821773 1.0 0.1292597233206925 2 P36896 1 +Mating behavior 0.9455958565975942 2.744068907481274 0.0060682798564495 1.0 0.1292597233206925 4 P05067 1 +Reproductive behavior 0.9455958565975942 2.744068907481274 0.0060682798564495 1.0 0.1292597233206925 4 P05067 1 +Locomotion 0.4006319143093941 2.7401598871579966 0.0061409302770134 1.0 0.1292597233206925 260 Q08722,Q15375,P05556,Q13277,P04062,P05067,Q13641,Q04656,Q96N67,P42892,Q06481,Q9H4H8,P08069,Q92859,Q9Y624,Q07954,P21359,Q16539,Q99538,Q8WTV0,O43293,P78310,P36896,Q07021,O94813,P04083,P23229,P04114,P31751,P62258,P07686,A0MZ66,P43121,P15291,Q5VTR2,Q9NWW5,Q13685,Q9UHI8,P42785,Q5JRA6,Q11206,Q7Z739,Q96G23,P06756,P09493,P19022,Q96N66,P31749,O00560,P40763 50 +Protein containing complex remodeling 0.942460902921216 2.737673893276657 0.0061875398181987 1.0 0.1292597233206925 2 Q8WTV0 1 +Mammary gland epithelial cell differentiation 0.942165830628501 2.7364505867759807 0.0062105921497752 1.0 0.1292597233206925 2 P31749 1 +Positive regulation of glycogen metabolic process 0.942165830628501 2.7364505867759807 0.0062105921497752 1.0 0.1292597233206925 2 P31749 1 +Glycolipid transport 0.940680472706707 2.726677545776627 0.0063975524307287 1.0 0.1292597233206925 3 P07602 1 +Negative regulation of lipase activity 0.9401308481337748 2.7243869905891316 0.0064420972780816 1.0 0.1292597233206925 3 Q99523 1 +Oligosaccharide biosynthetic process 0.9389200354086708 2.7229824322331684 0.0064695498035529 1.0 0.1292597233206925 2 Q11206 1 +Disaccharide metabolic process 0.93892003540867 2.722982432233157 0.0064695498035531 1.0 0.1292597233206925 2 P10253 1 +Regulation of chaperone mediated autophagy 0.9394235717571447 2.7182619122912377 0.0065625867156626 1.0 0.1292597233206925 4 P10619 1 +Positive regulation of long term synaptic potentiation 0.937508846777431 2.7102402270810777 0.0067234492358956 1.0 0.1292597233206925 4 P05067 1 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.9363711000120476 2.708701576328861 0.0067547065739306 1.0 0.1292597233206925 3 Q06481 1 +Chondroitin sulfate proteoglycan metabolic process 0.9369008323729048 2.7076913795724304 0.0067752994508278 1.0 0.1292597233206925 4 Q9NRB3,Q9NX62 2 +Cellular protein catabolic process 0.4013817360104478 2.705043235060258 0.0068295499928689 1.0 0.1292597233206925 247 P07858,Q9BZK7,O95816,P04062,P98164,O14773,Q9H2J4,Q9UNS2,Q07954,Q13619,P15311,Q96HY6,Q9Y5K6,Q99538,P28070,Q9UJX4,Q9Y3E7,O43464,Q9H3S7,Q13620,P19784,Q92783,Q9Y4E8,P50897,Q9Y4X5,P53634,Q9H1I8,Q8IXB1,P53350,Q9H3F6,O94822,Q96KB5,P13473,Q9Y297,Q9Y263,P49721,Q9NWU2,Q15386,P49720,P20618,Q5VTR2,O43567,P60604,Q7L5Y9,Q9UHG3,Q9UNN5,Q9NQ11,Q9UJX5,P46934,Q9GZU8,P31749,Q9GZP4,P46379,Q9NUM4,O00560,P17655,Q9BRG1,Q9UN37,O75844,P28074,P28072 61 +Protection from natural killer cell mediated cytotoxicity 0.934493951018 2.7045819002676157 0.00683904083361 1.0 0.1292597233206925 2 P01889 1 +Negative regulation of natural killer cell mediated immunity 0.934493951018 2.7045819002676157 0.00683904083361 1.0 0.1292597233206925 2 P01889 1 +Detection of other organism 0.934493951018 2.7045819002676157 0.00683904083361 1.0 0.1292597233206925 2 P01889 1 +Aminoglycan metabolic process 0.930996548732255 2.702842361939513 0.0068749342836007 1.0 0.1292597233206925 20 Q7LGA3,Q01459,P04066,P08236,P06865,Q93063,P16278,P07686,Q9NRB3,Q9NX62,P54802,Q9NWW5,P15586,O43505,Q11206,Q8NCH0 16 +Detection of external biotic stimulus 0.9347697756788654 2.7020121015996605 0.0068921253812443 1.0 0.1292597233206925 3 P01889,Q8WTV0 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.9347697756788644 2.7020121015996605 0.0068921253812443 1.0 0.1292597233206925 3 P10321,P01889 2 +Chondroitin sulfate proteoglycan biosynthetic process 0.9336738176290338 2.6974307224652017 0.0069876822589673 1.0 0.1292597233206925 3 Q9NRB3 1 +Chondroitin sulfate biosynthetic process 0.9336738176290338 2.6974307224652017 0.0069876822589673 1.0 0.1292597233206925 3 Q9NRB3 1 +Cellular response to manganese ion 0.933614861893256 2.69718420234879 0.0069928576685798 1.0 0.1292597233206925 3 P05067 1 +Ion homeostasis 0.4495239587748412 2.691688941350032 0.0071091216918277 1.0 0.1292597233206925 120 Q04656,P05067,O75503,Q92859,P02786,Q92544,P50897,Q15904,Q93050,P61421,P51790,P62258,Q9Y487,Q7L0J3,P62942,P07686,Q9NWW5,Q8TAD4,Q9NQ11,Q9NWR8,P35670,Q93063,Q9NUM4 23 +Angiogenesis involved in wound healing 0.931142709281815 2.6835148200140284 0.0072852746232601 1.0 0.1292597233206925 4 P43121,P42785 2 +Penetration of zona pellucida 0.930342384887836 2.683489245500662 0.007285831847994 1.0 0.1292597233206925 3 P15291,P07686 2 +Regulation of lysosome organization 0.9288875774564695 2.681216663381914 0.0073355004635375 1.0 0.1292597233206925 2 Q14108 1 +Protein o linked glycosylation via threonine 0.928297432871052 2.678753393384228 0.0073896795701775 1.0 0.1292597233206925 2 Q10472 1 +Leptin mediated signaling pathway 0.928002360578342 2.6775214886938628 0.0074169094730702 1.0 0.1292597233206925 2 Q16739 1 +Cellular response to leptin stimulus 0.928002360578342 2.6775214886938628 0.0074169094730702 1.0 0.1292597233206925 2 Q16739 1 +Negative regulation of cell killing 0.9287333980674995 2.676747680960042 0.0074340596320821 1.0 0.1292597233206925 3 P01889 1 +Response to leptin 0.928276269185355 2.6748313578609886 0.0074766849498346 1.0 0.1292597233206925 3 P98164,Q16739 2 +Glycoside catabolic process 0.9297100408609432 2.671957141783708 0.0075410279147687 1.0 0.1292597233206925 6 P04062,P04066,Q9BTY2,P06280 4 +Glycosylceramide catabolic process 0.9270085093071384 2.6695145334729085 0.0075960985667276 1.0 0.1292597233206925 3 P06280 1 +Membrane lipid catabolic process 0.9259655220366504 2.6543469017140047 0.0079462089051558 1.0 0.1292597233206925 12 Q99519,P04066,P06280,P06865,P17900,Q13510,P07686,P50897 8 +Cerebellar purkinje cell layer formation 0.9215107701386792 2.6503740404427516 0.0080402701790021 1.0 0.1292597233206925 2 P04062 1 +Copper ion import 0.9215107701386782 2.6503740404427516 0.0080402701790021 1.0 0.1292597233206925 2 P35670 1 +Copper ion transmembrane transport 0.9215107701386782 2.6503740404427516 0.0080402701790021 1.0 0.1292597233206925 2 P35670 1 +Retinal ganglion cell axon guidance 0.9198060731708176 2.63924508129109 0.0083090887515537 1.0 0.1292597233206925 3 O94813 1 +Oligosaccharide metabolic process 0.9222484709899492 2.636890651392759 0.0083669798067687 1.0 0.1292597233206925 10 O00462,Q01459,Q99519,P06280,P17900,P07686,P10253,Q11206 8 +Self proteolysis 0.916199468869864 2.6280975557563715 0.0085863887379846 1.0 0.1294899028263441 2 Q99538 1 +Synaptic transmission gabaergic 0.91807583087998 2.6251868645152983 0.0086601424961156 1.0 0.1294899028263441 5 Q13641,P51790 2 +Growth 0.424547005175002 2.6250811048470575 0.0086628329601186 1.0 0.1294899028263441 172 Q15375,P05556,O75414,Q9BZK7,P07602,Q7L576,P05067,Q9UJU6,Q96ST3,O75629,P02786,P15311,Q16539,Q9C0B1,Q99538,Q93074,O43909,O43464,P61586,P16989,P50897,P11413,P36896,Q7Z4V5,O94813,P04083,Q9Y263,O95251,A0MZ66,Q6IAA8,P06493,Q8NDZ4,O43598,Q9BTE7,Q9BRT9,P58546,Q99829,O75489,P10644,P43034,P31749,Q15056,Q5BJF2,O00560,P40763,O60934,O75844 47 +Glutathione catabolic process 0.9144290351136024 2.6206590458080226 0.0087759983566044 1.0 0.1294924725609061 2 Q8WUX2 1 +Amyloid precursor protein biosynthetic process 0.9152457470451408 2.6164100042628555 0.0088859785447115 1.0 0.1294924725609061 4 Q9Y287 1 +Regulation of vesicle mediated transport 0.4432542155581742 2.6137042349130426 0.0089566534191911 1.0 0.1294924725609061 121 Q08722,P05067,Q06481,Q9H223,Q08431,Q07954,Q12907,Q9Y6B6,Q9Y3E7,Q8WTV0,P50897,P04083,P31751,P11279,Q9NQ11,Q9H4M9,P06756,O75955,O00560,Q9UN37,Q6UWE0,Q4J6C6 22 +Negative regulation of developmental process 0.4437711549363007 2.613157922831881 0.0089709838901641 1.0 0.1294924725609061 113 Q96AC1,Q15375,P05556,Q99523,Q9UQ16,P05067,Q9UBS4,Q06481,P23634,Q99536,Q9P258,P02786,Q13619,P49591,P21359,Q99538,P61586,P11413,Q9Y6I3,P04083,Q9UPY3,Q8N4Q0,P67809,P13693,Q9UHI8,Q86X55,Q96G23,P06756,Q04917,P40763,Q8N5W9 31 +Mucopolysaccharide metabolic process 0.9136597122888296 2.600448055048179 0.0093102112989715 1.0 0.1330668930236453 12 Q93063,P16278,Q9NX62,Q9NRB3,P15586,O43505,Q11206,Q8NCH0 8 +Aminoglycan biosynthetic process 0.9120802507826204 2.5928570591189546 0.0095182321378772 1.0 0.1330668930236453 11 Q7LGA3,P06865,Q93063,Q9NRB3,O43505,Q11206,Q8NCH0 7 +Fc gamma receptor signaling pathway 0.9089171139684646 2.589548256191538 0.0096101952367311 1.0 0.1330668930236453 4 Q06481 1 +Tube morphogenesis 0.4415793570061459 2.5857025342938535 0.0097180759573725 1.0 0.1330668930236453 113 Q15375,P98164,Q9H2J4,Q9NZ08,Q08431,Q07954,P21359,Q16539,Q93074,O94813,Q9Y6I3,P04083,P04114,P43121,P15291,Q13685,Q9UHI8,P42785,Q5JRA6,P06756,P19022,P31749,P40763 23 +Skin morphogenesis 0.9055768663322448 2.583368654630088 0.0097840713592114 1.0 0.1330668930236453 2 P04062 1 +Tube development 0.4331784490704087 2.5825089145259743 0.0098084828163913 1.0 0.1330668930236453 148 Q15375,P05556,Q04656,Q16706,P98164,P42892,Q9H2J4,P38571,Q08431,Q9NZ08,Q07954,P21359,Q16539,Q93074,O94813,Q9Y6I3,P04083,P04114,P43121,P15291,Q13685,Q9UHI8,P42785,Q5JRA6,P06756,P19022,P31749,P46379,Q13572,P40763 30 +Negative regulation of fatty acid transport 0.9060394965362132 2.581087939070446 0.0098489489906232 1.0 0.1330668930236453 3 P31749 1 +Positive regulation of cell population proliferation 0.4390170199220182 2.578294901879828 0.0099289221807017 1.0 0.1330668930236453 129 Q08722,P05556,Q13277,Q969Z0,Q04656,P98164,Q9H2J4,P08069,P07384,P02786,P21359,Q16539,Q99538,P04083,P31751,Q9NWU2,O95251,P15291,Q9UHI8,Q86X55,P55209,P04439,P06756,P31749,O00560,P40763,O60884 27 +Proteoglycan metabolic process 0.9087277721699852 2.5781710594540095 0.0099324815237742 1.0 0.1330668930236453 11 Q7LGA3,Q8WVQ1,Q93063,Q9P2E5,Q9NX62,Q9NRB3,Q8NCH0,Q99805 8 +Actin myosin filament sliding 0.9052538370720148 2.5777569570410126 0.0099443914571741 1.0 0.1330668930236453 3 P09493,P14649 2 +Regulation of heart rate by chemical signal 0.9041015048686944 2.577137709044473 0.0099622252867812 1.0 0.1330668930236453 2 P09493 1 +Proteoglycan biosynthetic process 0.9075069757562456 2.57274409265156 0.0100895780375416 1.0 0.1330668930236453 10 Q7LGA3,Q8WVQ1,Q93063,Q9P2E5,Q9NRB3,Q8NCH0,Q99805 7 +O glycan processing 0.9058961671512508 2.5702902687663225 0.0101613334011843 1.0 0.1330668930236453 6 Q86SF2,Q10472,Q11206,O43505 4 +Heart trabecula formation 0.9023310711124136 2.5696545757120974 0.0101799964476494 1.0 0.1330668930236453 2 Q9UHI8 1 +Trabecula formation 0.9023310711124136 2.5696545757120974 0.0101799964476494 1.0 0.1330668930236453 2 Q9UHI8 1 +Sphingosine biosynthetic process 0.9023475641525456 2.561574968947069 0.0104198749929436 1.0 0.1330668930236453 4 Q13510 1 +Cellular response to nitrogen compound 0.4334070748645977 2.5563661600250205 0.0105771752177943 1.0 0.1330668930236453 141 Q7L576,P05067,Q04656,Q96ST3,Q06481,P23634,O00410,P08069,Q07954,Q5KU26,Q99538,Q8TBX8,O94813,P31751,P61160,P34896,Q9NUD5,P41440,P11234,O75955,P31749,O95831,Q9UQB8,P17655,P40763,P29992,Q92572,Q92542 28 +Negative regulation of lymphocyte migration 0.8987902035998734 2.5546686609373968 0.0106288921902868 1.0 0.1330668930236453 2 P31749 1 +Cellular response to oxidised low density lipoprotein particle stimulus 0.8987902035998734 2.5546686609373968 0.0106288921902868 1.0 0.1330668930236453 2 P31749 1 +Cardiac atrium development 0.8982000590144599 2.552168459730202 0.0107054742930026 1.0 0.1330668930236453 2 P08069 1 +Negative regulation of mononuclear cell migration 0.8990554899645746 2.551432287267499 0.0107281168369983 1.0 0.1330668930236453 3 P31749,O94813 2 +Lipoprotein localization 0.900118203309701 2.5434845750498845 0.0109752902731661 1.0 0.1330668930236453 7 Q9Y6B6,P04114,Q96GC9,O15260,A6NIH7,Q07954 6 +Heparan sulfate proteoglycan metabolic process 0.8992318338740604 2.5416238946609004 0.0110338833131198 1.0 0.1330668930236453 6 Q7LGA3,Q93063,Q99805 3 +Heparan sulfate proteoglycan biosynthetic process 0.8992318338740604 2.5416238946609004 0.0110338833131198 1.0 0.1330668930236453 6 Q7LGA3,Q93063,Q99805 3 +Cell volume homeostasis 0.8965124491229177 2.5406085516379187 0.011065973646374 1.0 0.1330668930236453 3 P51790 1 +Cell differentiation in hindbrain 0.8952493360873433 2.5396565218039595 0.0110961382319643 1.0 0.1330668930236453 2 Q04656 1 +Positive regulation of osteoblast proliferation 0.8940690469164961 2.5346466424952054 0.0112560804098571 1.0 0.1330668930236453 2 P08069 1 +Regulation of macrophage derived foam cell differentiation 0.8940690469164884 2.5346466424951712 0.0112560804098582 1.0 0.1330668930236453 2 P04114 1 +Negative regulation of low density lipoprotein receptor activity 0.8940690469164818 2.5346466424951366 0.0112560804098593 1.0 0.1330668930236453 2 P05067 1 +Vasculature development 0.4745695400234987 2.5339218927689666 0.0112793870145011 1.0 0.1330668930236453 101 Q04656,P98164,Q9H2J4,Q9NZ08,Q08431,Q07954,P21359,Q16539,Q9Y6I3,O94813,P04083,P04114,P43121,P15291,Q13685,Q9UHI8,P42785,Q5JRA6,P06756,P19022,P31749,P40763 22 +Positive regulation of cholesterol storage 0.8946280991735494 2.532579584951092 0.0113226663406484 1.0 0.1330668930236453 3 P04114,Q8WTV0 2 +Defense response 0.398955751070559 2.53005947014921 0.0114043195021491 1.0 0.1330668930236453 216 Q08722,P10321,P05556,O15111,P04062,P05067,Q06481,O00584,P38571,Q9NZ08,Q9Y624,Q9UQR1,P02786,Q8ND90,Q8IZ81,Q5KU26,Q16539,P28070,Q9Y3E7,P01889,O43293,Q08380,Q14671,P53634,Q07021,P04083,Q9BY67,Q8IV08,P11279,P15291,P42785,P61160,P04439,Q7Z739,Q9NUD5,P31749,P40763,Q6UWE0 38 +Regulation of long chain fatty acid import across plasma membrane 0.8921155425806094 2.5218623005778253 0.0116735394548181 1.0 0.1330668930236453 3 P31749 1 +Regulation of phospholipase a2 activity 0.8923057280076767 2.518640981659537 0.0117808710379592 1.0 0.1330668930236453 4 P50897,Q07954 2 +Reproduction 0.3932309623853328 2.517905074218296 0.0118055133162602 1.0 0.1330668930236453 238 P05556,P07858,P07602,Q9UIQ6,Q04656,P05067,Q9UH99,Q15392,P98164,O60921,P08069,Q08431,P11717,Q9UQR1,Q16539,P19784,P68402,P19021,P78310,Q13472,Q14671,P36896,Q07021,O94813,Q9Y6I3,P04083,Q9BY67,P53350,P04114,Q13144,O14777,P07686,P15291,P23258,Q8NB78,Q9UHI8,Q16181,P61160,Q7Z739,P31749,Q9GZP4,P46379,Q15056,Q96GC9,O60934,P40763,P17655,Q9Y2W6 48 +Positive regulation of interleukin 1 beta production 0.8906349177507225 2.5155404925357217 0.0118850023850476 1.0 0.1330668930236453 3 P05067 1 +Protein catabolic process in the vacuole 0.8928058202461555 2.508999269142393 0.0121073734899239 1.0 0.1330668930236453 9 Q9NQ11,P13473,P04062,P98164,O14773,Q07954 6 +Lysosomal protein catabolic process 0.8928058202461555 2.508999269142393 0.0121073734899239 1.0 0.1330668930236453 9 Q9NQ11,P13473,P04062,P98164,O14773,Q07954 6 +Astrocyte development 0.8903055013671239 2.5063449044444335 0.0121986561796911 1.0 0.1330668930236453 5 P05067,Q07954 2 +Positive regulation of cellular component organization 0.3880284304162321 2.5033657528637256 0.0123018340426248 1.0 0.1330668930236453 254 Q08722,Q96AC1,Q9UQ16,Q7L576,P05067,Q13641,P04062,Q04656,Q9UJU6,Q8NEY8,Q06481,P08069,P02786,Q07954,Q16539,Q9UJX4,Q14108,Q8TBX8,O43464,Q9P2S5,Q14444,P50897,O94813,Q96HS1,Q15555,P04083,P23229,P31751,Q9NV96,Q32P28,A0MZ66,O15260,Q16181,P61160,Q14203,P39880,P41440,Q9UNN5,Q9UJX5,Q9H4M9,P09493,P11234,O75955,Q9NUM4,O00560,O60934,Q9UQB8,P17655,Q6UWE0 49 +Germ cell migration 0.8863971673059824 2.502011249769716 0.0123490000819677 1.0 0.1330668930236453 2 P78310 1 +Cellular response to low density lipoprotein particle stimulus 0.886397167305981 2.50201124976971 0.0123490000819679 1.0 0.1330668930236453 2 O15118 1 +Neuroinflammatory response 0.8863971673059781 2.502011249769697 0.0123490000819683 1.0 0.1330668930236453 2 P53634 1 +Head development 0.4211022204217924 2.499044375479035 0.0124528716437652 1.0 0.1333358460541317 163 Q15375,P05556,P04062,P05067,Q04656,Q96N67,O75503,P98164,Q96ST3,O75787,P23634,O15511,P08069,Q9UQR1,P21359,O15027,Q5KU26,O43464,P61586,P19784,P68402,P54802,P50897,P11413,O94813,Q9BY67,Q13144,P61421,P62258,Q16352,Q8N3R9,P58546,Q8NCM8,O75489,P19022,P43034,Q96N66,P46379,Q04917,O14949,Q9UQB8,Q92688,Q9BRK5,Q92542,Q15154 45 +Aromatic amino acid transport 0.8852168781351337 2.4969794597023713 0.0125256211796576 1.0 0.1338945712308227 2 P08195 1 +Cellular response to lipoprotein particle stimulus 0.8869205786832102 2.4955290479748844 0.0125769457299595 1.0 0.1342228142656344 4 Q5JRA6,O15118,P31749 3 +Positive regulation of vascular associated smooth muscle cell migration 0.8840023612750817 2.487164891636719 0.0128765701374042 1.0 0.1347632387943279 3 Q04656,Q9UHI8 2 +Negative regulation of catalytic activity 0.4240057193643315 2.483774684443233 0.0129998032037517 1.0 0.1347632387943279 154 P07858,Q99523,O95816,P04062,P05067,Q15392,Q06481,Q13576,Q9Y624,Q07954,P21359,P06280,Q8TBX8,Q15070,O94813,P04083,Q9UBB9,P62942,Q01105,P10644,Q15041,P31749,P31946,Q9BRG1 24 +Regulation of immune system process 0.4046034066057869 2.4832145432124064 0.0130202642913477 1.0 0.1347632387943279 197 Q08722,P05067,Q06481,Q9NZ08,P02786,P21359,Q5KU26,Q16539,P28070,Q99538,P01889,Q14671,P53634,P36896,Q9HAT2,Q07021,O94813,Q9NPR9,Q8TCT8,Q9BY67,P04083,P11279,P62942,O95251,Q5JRA6,O15400,O96028,Q11206,P04439,Q7Z739,Q9NUD5,P10644,O75955,P31749,Q9GZP4,P40763 36 +Phagocytosis recognition 0.8832744655541478 2.479845889263306 0.0131439178162999 1.0 0.1347632387943279 4 Q08431,Q5KU26 2 +Xenobiotic export 0.8810858660371682 2.479345152951816 0.0131623867740846 1.0 0.1347632387943279 2 P35670 1 +Negative regulation of mitochondrial fusion 0.8817255837973661 2.4774029439126006 0.0132342397318767 1.0 0.1347632387943279 3 P02786 1 +Regulation of long chain fatty acid import into cell 0.8821447657989868 2.4749809640465337 0.0133243277540251 1.0 0.1351111739543671 4 P31749 1 +Chloride transmembrane transport 0.8827653156463526 2.4737952384568835 0.0133686293581885 1.0 0.1353416663023114 5 P51797,Q9UHG3,P51790 3 +Lysosomal lumen acidification 0.8821618428824489 2.4711849348932664 0.013466615718267 1.0 0.1354991992717789 5 Q9NUM4,Q9NWW5,P50897,O75503 4 +Positive regulation of multicellular organismal process 0.400398553027838 2.4706313457276905 0.0134874778998637 1.0 0.1354991992717789 205 P05556,O15111,P04062,P05067,Q13641,Q9UJU6,Q16706,P98164,Q9H9B1,Q06481,Q9H2J4,P08069,Q9NZ08,P02786,Q07954,Q16539,Q14444,P36896,Q07021,O94813,P04083,Q9BY67,A0MZ66,O96028,P55209,Q11206,P61160,P04439,Q9NUD5,P58546,P09493,O75955,P31749,O00560,Q9UQB8,P40763 36 +Synaptic membrane adhesion 0.8781351431100644 2.4667272622697594 0.0136354171111043 1.0 0.1356848828204471 2 Q16539 1 +Positive regulation of locomotion 0.5858876379561396 2.462976649029229 0.0137788889364711 1.0 0.1361161866106636 87 Q08722,P05556,Q13277,Q04656,P05067,Q13641,Q96N67,P08069,Q16539,Q99538,Q8WTV0,O43293,P36896,Q07021,O94813,P04083,P23229,P31751,A0MZ66,P43121,Q13685,Q9UHI8,Q5JRA6,P06756,P31749,O00560,P40763 27 +Insulin like growth factor receptor signaling pathway 0.8789539891142477 2.457296470912511 0.0139987107681658 1.0 0.1369577949743775 5 P11717,P31749 2 +Regulation of pinocytosis 0.8784873608770305 2.455274373280936 0.0140777094487256 1.0 0.1369669597447486 5 Q06481 1 +Positive regulation of pinocytosis 0.8784873608770305 2.455274373280936 0.0140777094487256 1.0 0.1369669597447486 5 Q06481 1 +Regulation of spontaneous synaptic transmission 0.8763767978943864 2.4544263908839334 0.0141109550835853 1.0 0.1369669597447486 3 P05067 1 +Spontaneous synaptic transmission 0.8763767978943864 2.4544263908839334 0.0141109550835853 1.0 0.1369669597447486 3 P05067 1 +Neuron maturation 0.8788278716707378 2.45326970771312 0.0141564152125654 1.0 0.1369669597447486 6 P05067 1 +Glucosylceramide metabolic process 0.8753988484427415 2.4502189268853343 0.0142769379391964 1.0 0.1372418127768948 3 P04062 1 +Estrous cycle 0.8752593650534348 2.4452713449920065 0.014474319723152 1.0 0.1375588633543355 4 P04083 1 +Cellular response to amyloid beta 0.876925473640143 2.4425894743990377 0.0145823144096031 1.0 0.1381817566324836 7 Q99538,P05067,Q07954 3 +Response to amyloid beta 0.876925473640143 2.4425894743990377 0.0145823144096031 1.0 0.1381817566324836 7 Q99538,P05067,Q07954 3 +Golgi to lysosome transport 0.8750619671898949 2.4404165231659776 0.0146703360514759 1.0 0.138528996928297 5 Q99523 1 +Regulation of growth 0.4292445156964681 2.43987742383327 0.0146922461998568 1.0 0.138528996928297 125 Q15375,O75414,Q7L576,P05067,Q9UJU6,Q96ST3,O75629,P02786,P15311,Q16539,Q9C0B1,Q99538,O43909,O43464,P61586,P16989,P50897,P11413,P36896,Q7Z4V5,O94813,Q9Y263,O95251,A0MZ66,Q6IAA8,P06493,O43598,Q9BTE7,P58546,O75489,P43034,P31749,Q5BJF2,O00560,P40763,O75844 36 +Positive regulation of rig i signaling pathway 0.8724911452184131 2.4376970940584513 0.0147811539571516 1.0 0.138528996928297 3 Q14671,Q9NUD5 2 +Aorta development 0.8760951601531612 2.43700215331876 0.0148095911736685 1.0 0.138528996928297 8 P98164 1 +Aminophospholipid translocation 0.8710534080849719 2.436369605620977 0.0148355171476171 1.0 0.138528996928297 2 Q9NV96 1 +Glycosphingolipid metabolic process 0.8763509256590072 2.436344974953434 0.0148365274832031 1.0 0.138528996928297 14 Q99519,O60512,P06280,P06865,P04062,P17900,P07686,P16278,Q9NWW5,Q99805 10 +Response to dietary excess 0.8731199670749896 2.436019671094278 0.0148498769468849 1.0 0.138528996928297 4 Q06481,Q9BZK7 2 +Positive regulation of immune system process 0.4295053127130992 2.433631649581698 0.0149481984057777 1.0 0.138528996928297 112 Q08722,P04083,Q9BY67,O15400,Q99538,P11279,P05067,P31749,Q06481,P01889,P53634,Q07021,P02786,P04439 14 +Aminophospholipid transport 0.871310507674135 2.4326076600692628 0.0149905342792278 1.0 0.138528996928297 3 Q14108,Q9NV96 2 +Retinal rod cell differentiation 0.868102685157849 2.4236894296542495 0.0153637382153963 1.0 0.138528996928297 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.868102685157849 2.4236894296542495 0.0153637382153963 1.0 0.138528996928297 2 P54802 1 +Retinal rod cell development 0.868102685157849 2.4236894296542495 0.0153637382153963 1.0 0.138528996928297 2 P54802 1 +Positive regulation of cyclase activity 0.8682414455765409 2.419363925578756 0.0155476765706525 1.0 0.1394124601683752 3 P21359 1 +Schwann cell proliferation 0.8666273236943076 2.4173424669006556 0.0156342998011067 1.0 0.1394124601683752 2 Q96G23 1 +Negative regulation of schwann cell proliferation 0.8666273236943076 2.4173424669006556 0.0156342998011067 1.0 0.1394124601683752 2 Q96G23 1 +Hematopoietic stem cell proliferation 0.8680249198405275 2.4139474477237006 0.0157807382766705 1.0 0.1394124601683752 4 P04062 1 +Peptide catabolic process 0.8713277760458301 2.412510132307133 0.0158430970781515 1.0 0.1394124601683752 12 Q6P179,Q9UJ14,Q9UIQ6,P42892,O14773,Q8WUX2,Q9NZ08 7 +Regulation of chondrocyte differentiation 0.8682555921569448 2.410819418227094 0.0159167270359401 1.0 0.1394124601683752 5 Q92896 1 +Regulation of cartilage development 0.8682555921569448 2.410819418227094 0.0159167270359401 1.0 0.1394124601683752 5 Q92896 1 +Cholesterol storage 0.8669161320288498 2.4091367847474503 0.0159903036610893 1.0 0.1397273514546195 4 P04114,Q8WTV0 2 +Regulation of cardiac muscle cell proliferation 0.8636766007671857 2.4046347892680107 0.0161886350110453 1.0 0.1403302449026704 2 Q16539 1 +Positive regulation of cardiac muscle cell proliferation 0.8636766007671857 2.4046347892680107 0.0161886350110453 1.0 0.1403302449026704 2 Q16539 1 +Negative regulation of fatty acid oxidation 0.8643098098193133 2.402368908002761 0.0162892718258313 1.0 0.1403949736383849 3 Q06481 1 +Negative regulation of synapse organization 0.8627913838890405 2.4008189100706927 0.0163584296602998 1.0 0.1403949736383849 2 Q15375 1 +Antigen processing and presentation of exogenous peptide antigen 0.8645205928444611 2.3945361267323855 0.0166414039614242 1.0 0.1403949736383849 5 Q99538,Q9UIQ6 2 +Presynapse organization 0.863907957347453 2.3918624168630176 0.0167631248870285 1.0 0.1403949736383849 5 P05067 1 +Regulation of bone remodeling 0.86120147056272 2.3889095818293895 0.0168984606418025 1.0 0.1403949736383849 3 P02786 1 +Regulation of bone resorption 0.86120147056272 2.3889095818293895 0.0168984606418025 1.0 0.1403949736383849 3 P02786 1 +T cell differentiation involved in immune response 0.8622638505524054 2.384683135699178 0.01709383753418 1.0 0.1411092832491446 5 P04083,P40763 2 +Zymogen activation 0.863718264389249 2.3846194288604887 0.0170967976242404 1.0 0.1411092832491446 7 Q15392 1 +Cellular defense response 0.8609388839681285 2.383158590880429 0.0171647978596489 1.0 0.1411092832491446 4 P05556,Q9UQR1,Q08380 3 +Regulation of synaptic transmission dopaminergic 0.85836529949838 2.381714755661811 0.017232239659455 1.0 0.1411092832491446 2 O75955 1 +Positive regulation of heterotypic cell cell adhesion 0.85836529949838 2.381714755661811 0.017232239659455 1.0 0.1411092832491446 2 O75955 1 +Positive regulation of toll like receptor 3 signaling pathway 0.85836529949838 2.381714755661811 0.017232239659455 1.0 0.1411092832491446 2 O75955 1 +Xenobiotic transmembrane transport 0.8583652994983666 2.3817147556617537 0.0172322396594577 1.0 0.1411092832491446 2 Q9NV96 1 +Cell adhesion molecule production 0.8586186540731894 2.3777102767942444 0.0174205073175601 1.0 0.1415824002962755 3 O75955,Q5KU26 2 +Positive regulation of cell adhesion molecule production 0.8586186540731894 2.3777102767942444 0.0174205073175601 1.0 0.1415824002962755 3 O75955,Q5KU26 2 +Phosphatidylethanolamine metabolic process 0.8585582340985982 2.3727907682738043 0.0176542614194068 1.0 0.1425921114644399 4 Q9HBU6 1 +Positive regulation of myoblast fusion 0.8591258121677419 2.3709643777147957 0.0177417409303828 1.0 0.142767284866245 5 O75955,Q16539,P17655,Q9H4M9 4 +Regulation of myoblast fusion 0.8591258121677419 2.3709643777147957 0.0177417409303828 1.0 0.142767284866245 5 O75955,Q16539,P17655,Q9H4M9 4 +Biological process involved in interspecies interaction between organisms 0.3776261541103888 2.3702279836189017 0.0177771196697773 1.0 0.1428154737440095 276 Q08722,P10321,P07858,P05556,P08195,O15118,Q06481,O00584,Q9NZ08,P11717,Q9Y624,P02786,Q8IZ81,Q5KU26,Q16539,Q14108,Q8WTV0,Q9BTY2,P01889,O43293,P78310,Q14671,Q07021,P04083,Q9BY67,P04114,P11279,P61916,P27105,P61160,P04439,Q7Z739,Q9NUD5,P06756,P46934,P31749,Q9UQB8,P17655,Q9UN37,Q6UWE0 40 +Exocyst localization 0.8554145765712515 2.3689557281189777 0.0178383885938007 1.0 0.1430146671744367 2 O60645 1 +Retina morphogenesis in camera type eye 0.8570747435223542 2.366324033504175 0.0179657124553904 1.0 0.1431413866023386 4 P54802,Q16706 2 +Artery morphogenesis 0.8594741100032721 2.3659112724940377 0.0179857542748522 1.0 0.1431413866023386 7 P21359,P98164,Q07954 3 +Glutamate receptor signaling pathway 0.8578744685564732 2.365487959006367 0.0180063288141687 1.0 0.1431413866023386 5 P05067 1 +Monocyte chemotaxis 0.8570612014788657 2.3580356637982787 0.0183719278342919 1.0 0.143578945244776 6 Q99538,O94813 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.8551749185056742 2.358035629074347 0.0183719295528261 1.0 0.143578945244776 4 Q06481 1 +Regulation of response to external stimulus 0.4215691367400639 2.3531675943481845 0.018614242303518 1.0 0.1446590924045953 131 Q08722,Q13277,P04062,P05067,Q13641,Q06481,P08069,Q9NZ08,Q8IZ81,Q16539,P28070,Q99538,P01889,Q14671,P53634,Q07021,O94813,P04083,Q9BY67,P11279,Q11206,P04439,Q7Z739,Q9NUD5,P80303,Q6UWE0 26 +Regulation of triglyceride metabolic process 0.8534281713851082 2.350408311195364 0.0187528271842327 1.0 0.145205867664161 4 Q96N66,Q8WTV0 2 +Neutral amino acid transport 0.8537054112770799 2.347218338521403 0.0189141675448403 1.0 0.145205867664161 5 Q9H2J7 1 +L glutamate import across plasma membrane 0.8515348288075499 2.3469218928159807 0.0189292224473047 1.0 0.145205867664161 3 P05556,Q15041 2 +Regulation of amino acid transmembrane transport 0.8515348288075499 2.3469218928159807 0.0189292224473047 1.0 0.145205867664161 3 P05556,Q15041 2 +Regulation of l glutamate import across plasma membrane 0.8515348288075499 2.3469218928159807 0.0189292224473047 1.0 0.145205867664161 3 P05556,Q15041 2 +Skeletal muscle tissue regeneration 0.8533756750394701 2.3457717930316764 0.0189877291385855 1.0 0.145205867664161 5 P04083,Q7Z4V5 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8504509892971006 2.342201859321371 0.0191703434278038 1.0 0.1458726668768346 3 Q9UIQ6 1 +Macromolecule depalmitoylation 0.8534183035129825 2.3419983599740513 0.0191807992083825 1.0 0.1458726668768346 6 Q9UMR5 1 +Regulation of neurotransmitter receptor activity 0.8484337399125348 2.333410297132977 0.0196266213472573 1.0 0.1476384759284482 3 P05067 1 +Regulation of nmda receptor activity 0.8484337399125348 2.333410297132977 0.0196266213472573 1.0 0.1476384759284482 3 P05067 1 +Positive regulation of fibroblast migration 0.8489909324891469 2.3310036676516876 0.0197531662878154 1.0 0.1476384759284482 4 P31749 1 +Positive regulation of dendrite development 0.8459722632044747 2.328003629109613 0.0199119109635266 1.0 0.1480857923108545 2 Q9NUM4 1 +Multicellular organism reproduction 0.4198621639823976 2.327365791493577 0.0199458048411702 1.0 0.1480857923108545 130 P05556,P07858,P05067,P08069,P11717,Q9UQR1,P19784,P68402,P19021,P78310,Q14671,O94813,P04083,Q9BY67,P04114,O14777,P07686,P15291,Q8NB78,Q9UHI8,Q16181,P31749,Q9GZP4,P46379,Q9Y2W6 25 +Oligodendrocyte progenitor proliferation 0.8469768400217734 2.3270555039129346 0.0199623113291187 1.0 0.1480857923108545 3 P98164 1 +Positive regulation of smooth muscle cell migration 0.8477790868640755 2.3256968539517566 0.020034728448997 1.0 0.1483800707656092 4 Q04656,Q9UHI8 2 +Dna methylation involved in gamete generation 0.8460904936595179 2.3231871935987938 0.0201690984434135 1.0 0.1486523699818658 3 Q8NB78 1 +Smad protein signal transduction 0.8504433639740618 2.3215297812942017 0.0202582686957988 1.0 0.1486523699818658 9 Q9UIQ6 1 +Type b pancreatic cell development 0.8454126284838588 2.3202276458191724 0.0203285658153682 1.0 0.1486523699818658 3 P31749 1 +Regulation of phosphatidylcholine metabolic process 0.8456923138544072 2.3165513446292367 0.0205281844260671 1.0 0.1486523699818658 4 P17655 1 +Regulation of mitochondrial fusion 0.846419946975205 2.315203320980697 0.0206018076046217 1.0 0.1486893209601855 5 Q99536,P02786 2 +Vacuolar acidification 0.8480745715344262 2.310932458057378 0.0208365858890851 1.0 0.1500510775862212 9 P61421,Q9Y487,O75503,Q9NUM4,Q9NWW5,P50897,Q93050 7 +Neuron projection arborization 0.8452159643820782 2.3027790003547883 0.0212912806389664 1.0 0.1518140601967926 7 Q13641 1 +Regulation of cell differentiation 0.384212759499428 2.2999207584644816 0.0214527098084114 1.0 0.1522410323666826 222 Q96AC1,Q15375,P05556,Q99523,Q7L576,P05067,Q9UBS4,Q96N67,Q16706,P98164,Q96ST3,Q06481,Q9UJU6,Q9Y624,Q9P258,P21359,Q16539,Q9C0B1,Q14444,P01889,Q92896,P11413,P36896,Q07021,O94813,P04083,P04114,Q9UPY3,Q8N4Q0,P67809,O95251,A0MZ66,P06493,Q86X55,Q6GMV2,P55209,P61160,Q96PZ0,Q96G23,P39880,Q99829,P06756,Q9BYT8,P26583,P31749,Q9GZP4,Q04917,O00560,Q9UQB8,P40763,Q8N5W9,P29992,Q9Y6C9 53 +Anatomical structure formation involved in morphogenesis 0.4049349603889884 2.297205640918787 0.0216070414954003 1.0 0.1526633510786606 168 P04062,Q04656,P98164,Q9H2J4,Q08431,Q9NZ08,P21359,Q16539,Q93074,O94813,Q9Y6I3,P04083,P62942,P43121,P15291,Q16527,Q13685,Q9UHI8,P42785,Q5JRA6,P58546,Q9H4M9,P06756,P09493,Q93063,P10644,Q96N66,P31749,O75955,P40763,P17655 31 +Cellular response to increased oxygen levels 0.8424251629235935 2.293431171747633 0.0218231937242874 1.0 0.1526633510786606 6 Q15904,P61421 2 +Positive regulation of metallopeptidase activity 0.8380053113012577 2.2933043740152983 0.0218304875918662 1.0 0.1526633510786606 2 P40763 1 +Positive regulation of i kappab phosphorylation 0.8380053113012529 2.293304374015271 0.0218304875918677 1.0 0.1526633510786606 2 P31749 1 +Regulation of i kappab phosphorylation 0.8380053113012529 2.293304374015271 0.0218304875918677 1.0 0.1526633510786606 2 P31749 1 +Regulation of synapse assembly 0.8438726980006004 2.292104649845372 0.0218996051547089 1.0 0.1526633510786606 9 P05067,Q13641 2 +Transforming growth factor beta1 production 0.8377102390085607 2.2920166542989255 0.0219046821714681 1.0 0.1526633510786606 2 O75787 1 +Regulation of transforming growth factor beta1 production 0.8377102390085607 2.2920166542989255 0.0219046821714681 1.0 0.1526633510786606 2 O75787 1 +Neuromuscular synaptic transmission 0.8374151667158474 2.290728751697956 0.0219791066419825 1.0 0.1526633510786606 2 O60333 1 +Cellular ion homeostasis 0.4790249617347391 2.290512932961933 0.0219915997308928 1.0 0.1526633510786606 98 Q04656,P05067,O75503,P02786,Q92544,P50897,Q15904,Q93050,P61421,P51790,P62258,Q9Y487,Q7L0J3,P62942,P07686,Q9NWW5,Q8TAD4,Q9NQ11,Q9NWR8,P35670,Q9NUM4 21 +Pyramidal neuron differentiation 0.8397441614382031 2.2904323631677155 0.0219962652541305 1.0 0.1526633510786606 4 Q04656,P04062 2 +Negative regulation of fatty acid metabolic process 0.8397606064438505 2.2858411301199912 0.02226355449913 1.0 0.1526633510786606 5 Q06481 1 +Cd4 positive alpha beta t cell differentiation 0.8405944792049053 2.2853182918673247 0.0222941711355697 1.0 0.1526633510786606 6 P04083,P40763 2 +Regulation of epidermal growth factor activated receptor activity 0.8382552097054085 2.2838825098134423 0.0223784367999275 1.0 0.152868440259736 4 P05067 1 +Regulation of systemic arterial blood pressure by renin angiotensin 0.8353496606668671 2.2817083139620062 0.0225065669035451 1.0 0.1531010977451536 2 O75787 1 +Apolipoprotein a i mediated signaling pathway 0.8353496606668643 2.281708313961995 0.0225065669035458 1.0 0.1531010977451536 2 P06756 1 +Positive regulation of leukocyte adhesion to vascular endothelial cell 0.8353496606668462 2.2817083139619196 0.0225065669035502 1.0 0.1531010977451536 2 Q11206 1 +Regulation of leukocyte adhesion to vascular endothelial cell 0.8353496606668462 2.2817083139619196 0.0225065669035502 1.0 0.1531010977451536 2 Q11206 1 +Bone maturation 0.8355962219598512 2.277260782276546 0.0227706573770152 1.0 0.154115789876004 3 Q15125,Q8N5W9 2 +Regulation of systemic arterial blood pressure by hormone 0.835596221959846 2.2772607822765236 0.0227706573770165 1.0 0.154115789876004 3 P42892,O75787 2 +Regulation of syncytium formation by plasma membrane fusion 0.8382776195042414 2.2750406482830043 0.0229034915189869 1.0 0.154115789876004 6 O75955,Q16539,P17655,Q9H4M9 4 +Positive regulation of syncytium formation by plasma membrane fusion 0.8382776195042414 2.2750406482830043 0.0229034915189869 1.0 0.154115789876004 6 O75955,Q16539,P17655,Q9H4M9 4 +Negative chemotaxis 0.8358429288456025 2.2732610213592803 0.0230104549720557 1.0 0.154115789876004 4 P06756,Q15375,O94813 3 +Collagen catabolic process 0.8351864939274407 2.270368553387976 0.0231852308175235 1.0 0.1541734960388951 4 P07858 1 +Response to ph 0.8367586225210899 2.268296148927139 0.0233111624949724 1.0 0.154537339961579 6 Q99538,P04062,P51798,P19021 4 +White fat cell differentiation 0.8330138618478247 2.2659239573905228 0.0234560394979757 1.0 0.1550241798292607 3 Q9BZK7 1 +Lipid translocation 0.8346949593095939 2.2634428528416604 0.0236084036459822 1.0 0.1555979826194213 5 Q96GC9,P08183,Q9NV96 3 +Glycine biosynthetic process 0.8318101915180067 2.2606349295163892 0.0237818729195582 1.0 0.1555979826194213 3 P00374 1 +Positive regulation of mononuclear cell migration 0.836276255838376 2.2579698598237115 0.0239475385850509 1.0 0.156367578925458 9 Q08722,Q99538,P05067 3 +Regulation of anatomical structure morphogenesis 0.4078118038572266 2.25654944490453 0.0240362423848392 1.0 0.156789516959222 155 Q9NUQ9,Q96AC1,Q15375,P05556,Q9UQ16,Q7L576,Q9UJU6,Q9H2J4,P23634,Q9NZ08,Q9Y624,Q9P258,P02786,Q99536,P21359,P49591,P15311,Q93074,P61586,Q14444,O43293,Q07021,O94813,Q9Y6I3,Q96HS1,P04083,Q8TAA9,Q9Y263,P52789,P07686,A0MZ66,Q9UHI8,Q16181,P61160,P39880,P46934,P09493,P19022,P43034,Q04917,P11233,Q9UQB8,P40763,Q9UL25,O75844,Q9Y6C9 46 +Response to hepatocyte growth factor 0.833117098047726 2.2521074572382904 0.0243154821674158 1.0 0.1579740588546641 6 Q06481 1 +Fc receptor mediated stimulatory signaling pathway 0.8320514461130427 2.251732720674612 0.0243391675931226 1.0 0.1579740588546641 5 Q06481 1 +Toll like receptor 4 signaling pathway 0.8305001167192315 2.249692430286794 0.0244684763782874 1.0 0.1584593269714748 4 Q06481,O75955 2 +Regulation of toll like receptor 4 signaling pathway 0.8305001167192315 2.249692430286794 0.0244684763782874 1.0 0.1584593269714748 4 Q06481,O75955 2 +Transforming growth factor beta production 0.8301291720223984 2.24805385904786 0.0245727557783801 1.0 0.1588566436119709 4 P06756,O75787 2 +Chondrocyte development 0.828604681844789 2.2465348028980676 0.0246697729120479 1.0 0.1593256167236431 3 Q9NX62 1 +Regulation of lysosomal lumen ph 0.8323460457346263 2.2454202805001615 0.0247411646785227 1.0 0.1593690904153768 7 Q9NUM4,Q9NWW5,P50897,O75503 4 +Negative regulation of lipid transport 0.8299690908601037 2.242497982378396 0.0249292055621279 1.0 0.16000798643199 5 P31751,P31749 2 +Amino acid import across plasma membrane 0.830923472422699 2.2423419368721227 0.0249392813236004 1.0 0.16000798643199 6 P05556,P30825,Q15041,P08195 4 +Homeostatic process 0.3718628215207699 2.2397940212280085 0.0251042982085125 1.0 0.1600150760727288 318 P05556,Q9UIQ6,O15118,P04062,P05067,Q04656,Q96N67,O75503,Q9H9B1,Q06481,O14773,O75787,P08069,P38571,Q92859,Q9Y624,P02786,P21359,Q9Y6B6,Q16539,Q9C0B1,Q8WTV0,Q92544,P51797,P50897,P78310,Q15904,P36896,P10253,P11413,Q93050,Q8N183,Q96HS1,P04083,Q15555,P04114,P61421,P51790,P13473,P62258,Q9Y487,Q7L0J3,P62942,P07686,O95251,P13693,P61916,Q9NWW5,Q8TAD4,O15260,P42785,Q7L5Y9,Q14203,Q9UDY2,Q9NQ11,Q16739,Q9UBB6,P35670,Q9NWR8,Q9H4M9,Q93063,P06756,P19022,P31749,Q96RR1,P26583,Q9GZZ9,Q9NUM4,Q5BJF2,P40763,Q9BWH2,Q9Y6C9,Q92542 73 +Regulation of hippo signaling 0.8270168498042086 2.2395423905441714 0.0251206463512025 1.0 0.1600150760727288 3 Q16539 1 +Sterol import 0.8253172027146498 2.237767486495755 0.0252362217187762 1.0 0.1600185936897843 2 Q8WTV0 1 +Cellular copper ion homeostasis 0.828937991592744 2.233494236391369 0.0255163699836 1.0 0.1604942691722091 6 P35670,P05067 2 +Phosphatidylinositol acyl chain remodeling 0.824136913543805 2.2325841222087273 0.0255763821229264 1.0 0.1605614731150005 2 Q96N66 1 +Positive regulation of fatty acid biosynthetic process 0.8241369135438035 2.2325841222087175 0.0255763821229271 1.0 0.1605614731150005 2 P04083 1 +Vesicle tethering 0.8250836067749856 2.2310217358666717 0.0256796892670898 1.0 0.1607934098663937 3 O95772 1 +Regulation of neurotransmitter uptake 0.8261649609192104 2.2305246914299555 0.0257126301179464 1.0 0.1607934098663937 4 P05556,O75955 2 +Foam cell differentiation 0.8260068783784076 2.2298249879178544 0.0257590638190201 1.0 0.1607934098663937 4 P04114 1 +Negative regulation of lymphocyte mediated immunity 0.8242999493300469 2.227565580309657 0.0259094980663792 1.0 0.1615621000116175 3 P01889 1 +Regulation of metallopeptidase activity 0.8248906572034295 2.2248828850460387 0.0260891012586577 1.0 0.1620611156429978 4 Q07954 1 +Apoptotic cell clearance 0.8291399710255102 2.223830125574066 0.0261598757017786 1.0 0.1623458444409716 10 P04083,Q08431,Q8WTV0,Q07954 4 +Ovulation cycle process 0.8264081233931866 2.2222085439134185 0.0262692153289409 1.0 0.1627141691640398 6 P19021,O94813 2 +Antigen processing and presentation of exogenous antigen 0.8261745038766984 2.2148615324041674 0.0267695701668082 1.0 0.1653414627949921 8 Q99538,Q9UIQ6 2 +Ph reduction 0.8271102617885397 2.2120046341520165 0.0269663447359462 1.0 0.1661296283532654 12 P61421,P51790,Q9Y487,O75503,Q9NUM4,Q9NWW5,P50897,Q93050 8 +Transcytosis 0.82598452737599 2.2115259718549756 0.0269994353983136 1.0 0.1661296283532654 9 P98164,Q07954 2 +Cardiac septum morphogenesis 0.8229179169910823 2.2111597918734884 0.0270247736445634 1.0 0.1661296283532654 5 P98164,O94813 2 +Genitalia development 0.824177302812296 2.2088307862369234 0.027186412834137 1.0 0.1661628887183636 7 Q15392 1 +Myoblast fusion 0.8241335232125085 2.2086343067439196 0.0272000871181175 1.0 0.1661628887183636 7 P05556,Q16539,Q9H4M9,O75955,P17655 5 +Regulation of long term synaptic potentiation 0.8240899393412965 2.2084387016308886 0.0272137064440143 1.0 0.1661628887183636 7 Q99538,P05067,Q92542 3 +Artery development 0.8260218644637327 2.2081106767804104 0.0272365589202903 1.0 0.1661628887183636 11 P21359,P98164,Q07954 3 +Interleukin 12 production 0.8230338830680033 2.207135062982122 0.027304624812753 1.0 0.1661628887183636 6 Q08722,P01889,Q07021 3 +Phosphatidylcholine catabolic process 0.8194877762279115 2.2063143189475936 0.0273619994940224 1.0 0.1661628887183636 3 Q8NCC3 1 +Cell activation 0.4097265484922452 2.2051197899345545 0.0274456897262049 1.0 0.1665157876212436 135 Q08722,P05556,P04062,P05067,Q04656,Q9Y624,P02786,Q07954,Q16539,P78310,P53634,P04083,Q9BY67,P11279,P62942,O95251,O96028,P04439,P10644,P31749,P46379,O60934,P40763,Q9BWH2,Q92542 25 +Response to lead ion 0.8207405586996874 2.2014615942141917 0.027703362688279 1.0 0.1672995279227238 5 P05067 1 +Antigen processing and presentation of peptide antigen 0.8224633781817117 2.1897639475312447 0.0285413606542754 1.0 0.1704626218892966 14 P10321,Q9Y6B6,Q6P179,Q99538,Q9UIQ6,P01889,P04439 7 +Eating behavior 0.8129241664207587 2.1831971814325786 0.0290212922471047 1.0 0.1726952582528861 2 P40763 1 +Positive regulation of fatty acid beta oxidation 0.8129241664207568 2.1831971814325666 0.0290212922471055 1.0 0.1726952582528861 2 P31751 1 +Positive regulation of fatty acid oxidation 0.8129241664207568 2.1831971814325666 0.0290212922471055 1.0 0.1726952582528861 2 P31751 1 +Interleukin 1 production 0.8183508775023793 2.1795637227695255 0.0292898163422534 1.0 0.1739750952445895 8 P04083,P05067 2 +Cerebellar purkinje cell layer development 0.8173823691780274 2.178287099924674 0.0293846689695493 1.0 0.1742205783167272 7 Q04656,P54802,P04062 3 +Negative regulation of vascular permeability 0.8137200793727706 2.175280903376347 0.0296090726811542 1.0 0.1745637885137119 4 O94813 1 +Cytokine production involved in inflammatory response 0.8172392667232813 2.174537934459406 0.029664759721566 1.0 0.1745637885137119 8 Q06481,Q8IV08,P40763 3 +Acute inflammatory response 0.8146974632428681 2.174492809735135 0.0296681448112556 1.0 0.1745637885137119 5 P42785,P02786 2 +Positive regulation of fatty acid metabolic process 0.8134041925007559 2.1738744401558754 0.0297145660828006 1.0 0.1745637885137119 4 P04083,Q92604,P31751 3 +Antigen processing and presentation of endogenous peptide antigen 0.8162932638289908 2.1702588276654886 0.0299872437774066 1.0 0.1753038542941464 8 P10321,P01889,Q6P179,P04439 4 +Antigen processing and presentation of endogenous antigen 0.8162932638289908 2.1702588276654886 0.0299872437774066 1.0 0.1753038542941464 8 P10321,P01889,Q6P179,P04439 4 +Negative regulation of mrna 3 end processing 0.8152915624343684 2.1688691604516137 0.0300926186878531 1.0 0.1753038542941464 7 Q5VTR2 1 +Neurotransmitter gated ion channel clustering 0.8096783712009321 2.1688521430553496 0.0300939110433431 1.0 0.1753038542941464 2 Q9NQX3 1 +Receptor diffusion trapping 0.8096783712009321 2.1688521430553496 0.0300939110433431 1.0 0.1753038542941464 2 Q9NQX3 1 +Locomotory exploration behavior 0.8096783712009289 2.168852143055335 0.0300939110433442 1.0 0.1753038542941464 2 Q9HB07 1 +Positive regulation of excitatory postsynaptic potential 0.8096783712009248 2.1688521430553203 0.0300939110433453 1.0 0.1753038542941464 2 Q9UQB8 1 +Bone resorption 0.8151629142082889 2.1682893697104695 0.0301366767312221 1.0 0.1753038542941464 7 P21359,O14773,P02786 3 +Positive regulation of glucose import 0.8143135353834232 2.1680681521215908 0.0301535015628373 1.0 0.1753038542941464 6 P31751,P31749 2 +Maintenance of blood brain barrier 0.8142950855382154 2.167985327822342 0.0301598028893155 1.0 0.1753038542941464 6 Q9Y624,Q9UDY2 2 +Ectoderm development 0.8105077187330237 2.166527770437143 0.0302708801264681 1.0 0.1753776958336833 3 P23229 1 +Regulation of toll like receptor 3 signaling pathway 0.809327036599758 2.1612842207102343 0.0306733910613876 1.0 0.1767431128076798 3 P41440,O75955 2 +Golgi to vacuole transport 0.8131185807816236 2.159071308164571 0.030844635196541 1.0 0.1770938948026765 7 P11279,Q99523 2 +Motor behavior 0.8088174109096887 2.159020018214433 0.0308486139333694 1.0 0.1770938948026765 3 P04062 1 +Toll like receptor 3 signaling pathway 0.8095659875996708 2.15676849425441 0.0310237070960839 1.0 0.1779421437845871 4 P41440,O75955,Q5KU26 3 +Vitamin transmembrane transport 0.8115010838224211 2.151771656482459 0.0314153432390609 1.0 0.1784588869862884 7 P98164,P04062 2 +Lipoprotein catabolic process 0.8094562972069431 2.1510409178409757 0.0314729701741858 1.0 0.1786303712588925 5 P50897 1 +Response to nitrogen compound 0.3712180821164634 2.148521142503385 0.0316723786556174 1.0 0.1790837929574309 242 P05556,Q99523,P08195,O15118,Q7L576,P05067,Q04656,Q96ST3,Q06481,P23634,O00410,P08069,Q07954,P15311,Q5KU26,Q16539,Q99538,Q8TBX8,Q8IXB1,O94813,P04083,Q13144,P31751,P49721,O95251,P06493,P60604,Q5JRA6,Q86X55,P61160,P34896,P00374,Q9NUD5,P41440,Q9UNN5,P11234,O75955,P31749,P46379,O95831,Q9UQB8,P17655,P40763,P29992,Q92572,Q92542 46 +Vascular associated smooth muscle cell migration 0.8098444396702829 2.147984822674759 0.0317149611794485 1.0 0.1790837929574309 6 P09493,Q04656,Q96N67,Q9UHI8 4 +Natural killer cell differentiation 0.80495721451754 2.1479476685517933 0.0317179129462239 1.0 0.1790837929574309 2 O95251 1 +Regulation of multicellular organismal development 0.3852281889191786 2.1467293689503943 0.0318148332383272 1.0 0.1791648480808912 193 Q15375,P05556,Q7L576,Q96N67,Q9UBS4,Q13641,Q16706,P98164,Q9UJU6,Q06481,Q9H2J4,Q9H9B1,P23634,Q9NZ08,Q9Y624,Q13619,P21359,Q16539,Q14444,P01889,Q92896,P53634,P11413,P36896,O94813,Q9Y6I3,P04083,Q9UPY3,O95251,A0MZ66,P06493,Q9UHI8,P55209,Q16181,P61160,Q96G23,P39880,P26583,P31749,Q9GZP4,P46379,Q04917,Q9UQB8,P40763,Q8N5W9,O75844 46 +Positive regulation of anion transmembrane transport 0.8070019889155466 2.145324294619337 0.031926927355196 1.0 0.1792521680395337 4 P05556,Q15041 2 +Positive regulation of mitochondrial membrane potential 0.8079084335554403 2.1441039491740423 0.0320245587185781 1.0 0.1794478681380852 5 P31749 1 +Neuromuscular process controlling balance 0.8119697054909011 2.142370521089097 0.0321636781040834 1.0 0.1794603725233839 12 O14773,P17900,P05067,P10253 4 +Regulation of fatty acid beta oxidation 0.8062223761291649 2.1418418490364783 0.0322062105635418 1.0 0.1794603725233839 4 P31749 1 +Negative regulation of oxidoreductase activity 0.8059290870408692 2.1405314320719087 0.0323118434183657 1.0 0.1797864108150096 4 P06280 1 +Osteoblast proliferation 0.8053644323141871 2.1380080498195775 0.0325160899041647 1.0 0.1802379875098096 4 P06756,P08069 2 +Regulation of osteoblast proliferation 0.8053644323141871 2.1380080498195775 0.0325160899041647 1.0 0.1802379875098096 4 P06756,P08069 2 +Negative regulation of smooth muscle cell apoptotic process 0.8025966361758461 2.1374781587731344 0.0325591203243527 1.0 0.1802379875098096 2 Q8NDZ4 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.8103697135907123 2.1349830369565455 0.0327623957466129 1.0 0.1812091727361517 12 P10321,Q9Y6B6,Q6P179,Q9UIQ6,P01889,P04439 6 +Response to muscle stretch 0.8035124619516975 2.129727152398837 0.0331941459555844 1.0 0.1817524807723647 4 Q16539 1 +Syncytium formation 0.8071971810528684 2.129017586083811 0.0332528054437197 1.0 0.1817682409935963 8 P05556,Q16539,Q9H4M9,O75955,P17655 5 +Chaperone mediated autophagy 0.8072805137095466 2.1265409792170207 0.033458240902304 1.0 0.1824230722562811 9 P10619,P13473 2 +Positive regulation of cell differentiation 0.4057977854681702 2.1255581231476306 0.0335400696099845 1.0 0.1825634223754176 122 Q96AC1,Q7L576,Q9UJU6,Q16706,P98164,Q9Y624,Q16539,Q14444,P36896,Q07021,O94813,P04083,P04114,Q9UPY3,O95251,A0MZ66,Q86X55,P55209,P61160,P39880,Q99829,P26583,P31749,Q9GZP4,O00560,Q9UQB8,P40763,Q9Y6C9 28 +Glycoside metabolic process 0.8072966529207147 2.124211392109643 0.0336524710532732 1.0 0.1828694378604416 10 P04062,P04066,Q9BTY2,P06280 4 +Regulation of neutrophil chemotaxis 0.8049105554234784 2.121972324992188 0.0338400621267716 1.0 0.1835823370377359 7 O94813 1 +Negative regulation of myeloid leukocyte differentiation 0.7998852115616878 2.1192480858501006 0.0340695064411651 1.0 0.1843661570506941 3 P21359 1 +Regulation of glycoprotein metabolic process 0.8063124537754762 2.1177316537346895 0.0341978004891927 1.0 0.1844997229951618 11 Q92542,Q9Y287 2 +Myoblast migration 0.7978754794924575 2.116504706484788 0.0343019053454201 1.0 0.1844997229951618 2 P04083 1 +Regulation of proteolysis 0.3925485151836462 2.1165012494592825 0.0343021990516463 1.0 0.1844997229951618 169 Q15375,P07858,P04062,P05067,Q15392,Q06481,Q07954,Q99538,Q92896,P53634,Q9NWW5,Q9NQ11,Q9GZU8,Q15041,P31749,Q9GZP4,O00560,P40763,Q92542 19 +Plasma membrane raft organization 0.7989964580873605 2.11528177158565 0.0344059391269011 1.0 0.1844997229951618 3 P41440,O75955 2 +Plasma membrane raft assembly 0.7989964580873605 2.11528177158565 0.0344059391269011 1.0 0.1844997229951618 3 P41440,O75955 2 +Eye photoreceptor cell differentiation 0.8011424961742905 2.1137229726313196 0.0345389352210656 1.0 0.1849222139206571 5 P54802,P40763 2 +Tissue regeneration 0.8021612218602644 2.113360269260769 0.0345699438312503 1.0 0.1849222139206571 6 P04083,Q7Z4V5 2 +Leukocyte tethering or rolling 0.7981109799291484 2.1113284581514997 0.0347440896058903 1.0 0.1851488929218821 3 P05556,Q11206 2 +Glycosylceramide metabolic process 0.8013494273321735 2.109694727961338 0.0348846589021196 1.0 0.1851488929218821 6 P04062,O60512,P06280 3 +Regulation of fatty acid oxidation 0.8011321297824018 2.108713320150096 0.0349693343815862 1.0 0.1851488929218821 6 Q06481,P31749 2 +Liposaccharide metabolic process 0.8014672308308141 2.1080506306693345 0.0350266101680121 1.0 0.1851488929218821 23 Q99519,P04066,O60512,P06280,P06865,P17900,P04062,P16278,P07686,Q9NWW5,Q11206,Q99805 12 +Inorganic anion transmembrane transport 0.802556122068612 2.107908206106595 0.0350389302733884 1.0 0.1851488929218821 8 P51797,Q9UHG3,P51790,Q9UBX3 4 +Positive regulation of protein localization to cell surface 0.8007601917124791 2.107033262944573 0.0351146963940107 1.0 0.185300619708611 6 P31749,Q92544 2 +Leukocyte adhesion to vascular endothelial cell 0.7983466194272426 2.106591131364856 0.0351530361505583 1.0 0.185300619708611 4 P05556,Q11206,P61586 3 +Pyramidal neuron development 0.7962076290792586 2.102825287391439 0.0354810446853475 1.0 0.186576414298556 3 Q04656 1 +Protein localization to membrane raft 0.7968703867729563 2.099969486301855 0.0357315254159769 1.0 0.187439347669629 4 Q14254,P41440,O75955 3 +Negative regulation of molecular function 0.3727266542715939 2.098605107168588 0.0358517257848856 1.0 0.1879184660705356 221 P07858,Q99523,O15111,O95816,Q9C0C9,P04062,P05067,Q15392,Q96ST3,Q06481,P60866,P23634,O00410,Q13576,Q9Y624,P10586,Q07954,P21359,P06280,Q8TBX8,Q9BTT0,Q15070,O94813,P04083,P53350,P62258,Q9UBB9,P62942,P40855,Q9P2B4,Q9UNN5,P29375,Q99829,Q01105,P06756,P46934,Q9GZU8,P10644,Q15041,P11234,P31749,P31946,Q9BRG1 43 +Embryonic digit morphogenesis 0.799588715918641 2.097843206400301 0.035918998366315 1.0 0.1880474763784566 7 P42892 1 +Endosomal vesicle fusion 0.7947687919876198 2.0963923857489357 0.0360473972968213 1.0 0.1880474763784566 3 Q9UN37 1 +Cellular response to antibiotic 0.7960415461503676 2.096249754790675 0.0360600413654035 1.0 0.1880474763784566 4 Q04656 1 +Negative regulation of ossification 0.7941784732154828 2.093751900170731 0.0362820869696343 1.0 0.1880474763784566 3 Q8N5W9 1 +Negative regulation of bone mineralization 0.7941784732154828 2.093751900170731 0.0362820869696343 1.0 0.1880474763784566 3 Q8N5W9 1 +Ion transport 0.3724369413464431 2.0935652400606126 0.0362987267280705 1.0 0.1880474763784566 221 Q9H813,Q08722,P05556,P07602,P08195,Q9C0H2,P54709,Q9UBX3,Q04656,Q9UNF1,P05067,P30825,Q14728,P98164,Q7KZN9,P08183,P07384,P02786,Q9H2J7,P21359,Q13423,P51797,Q8NB49,Q70HW3,P11413,P04083,Q13555,P61421,P51790,P62258,Q7L0J3,P62942,P13693,P00403,Q6P4A7,Q8TAD4,P27105,P41440,Q9UHG3,Q9NQ11,Q9NWR8,P35670,P06756,P46934,Q15041,P31749,Q04917,P51798,Q96GC9,O75915,O75844 51 +Negative regulation of lipid localization 0.7977531231528476 2.0934397054391294 0.0363099211312445 1.0 0.1880474763784566 6 P31751,P31749 2 +Response to l glutamate 0.7973964896842403 2.0918262906538234 0.0364540576328129 1.0 0.1880474763784566 6 P08069,Q9UQB8 2 +Walking behavior 0.79482313808747 2.090779131838027 0.0365478676058159 1.0 0.1882330839508401 4 O15118,O43464 2 +Fc receptor signaling pathway 0.795817288803475 2.0897446312516275 0.0366407454842299 1.0 0.1884133120871537 5 Q06481 1 +Cdc42 protein signal transduction 0.7910888167600929 2.086275279062331 0.0369536946327264 1.0 0.1891262201722233 2 A0MZ66 1 +Cardiac conduction system development 0.7910888167600869 2.086275279062299 0.0369536946327293 1.0 0.1891262201722233 2 Q14126 1 +Regulation of cell projection organization 0.4024752379712885 2.0847325783547657 0.0370935817128805 1.0 0.1892714210792367 126 Q15375,Q9NR77,Q15334,Q9UQ16,Q7L576,Q04656,Q9UJU6,P08069,Q9P258,P10586,P15311,Q13308,Q14108,Q9P2S5,P61586,Q14444,Q96C92,O94813,Q5T0N5,P23229,Q15555,Q13555,Q9NV96,Q32P28,A0MZ66,Q86X55,Q16181,P61160,Q96G23,P39880,Q9H4M9,P46934,P19022,P43034,P31749,P11233,Q04917,Q9NUM4,Q9UQB8,Q9UL25,Q9Y3P9 41 +Animal organ maturation 0.7933823197614387 2.084305961467711 0.0371323454333547 1.0 0.1892714210792367 4 Q15125,Q8N5W9 2 +Entry of bacterium into host cell 0.7927377690520022 2.0814088086246336 0.0373965030947369 1.0 0.1892714210792367 4 Q9BTY2 1 +Regulation of entry of bacterium into host cell 0.7927377690520022 2.0814088086246336 0.0373965030947369 1.0 0.1892714210792367 4 Q9BTY2 1 +Positive regulation of cellular component biogenesis 0.4024800098146042 2.080612654419462 0.0374693746806571 1.0 0.1892714210792367 118 Q08722,Q96AC1,Q9UQ16,Q7L576,P23396,Q13641,Q04656,Q8NEY8,Q96ST3,P26358,P02786,Q8TBX8,Q13464,P61586,Q9P2S5,Q92783,Q9H2M9,Q96C92,Q5T0N5,Q15555,Q16181,P61160,Q14203,P41440,Q9UNN5,Q9NQ11,P09493,P11234,O75955,P11233,O00560,Q9UQB8,Q9UN37,Q6UWE0 34 +Astrocyte differentiation 0.7982531805668878 2.080536811407463 0.037476322852709 1.0 0.1892714210792367 11 P21359,P05067,Q07954 3 +Ceramide transport 0.7935278252415976 2.079417678089737 0.0375789770459871 1.0 0.189302977033606 5 P07602 1 +Regulation of epithelial cell proliferation involved in lung morphogenesis 0.7890233107111227 2.07705635411487 0.0377963582728386 1.0 0.189475794073043 2 P60953 1 +Positive regulation of epithelial cell proliferation involved in lung morphogenesis 0.7890233107111227 2.07705635411487 0.0377963582728386 1.0 0.189475794073043 2 P60953 1 +Diol metabolic process 0.7957635786017156 2.0769319241977766 0.0378078427804735 1.0 0.189475794073043 8 P00374,P04062,Q13510,P61457 4 +Diol biosynthetic process 0.7957635786017156 2.0769319241977766 0.0378078427804735 1.0 0.189475794073043 8 P00374,P04062,Q13510,P61457 4 +Regulation of modification of postsynaptic structure 0.7915559492176076 2.076094507709931 0.0378852110481997 1.0 0.1897174799413695 4 Q7L576,Q9UQB8,P61586 3 +Modulation of excitatory postsynaptic potential 0.7926606714489037 2.0755034460704076 0.0379398998139093 1.0 0.1898453095991927 5 P05067 1 +Cellular response to copper ion 0.7894642076834905 2.0726395115496583 0.0382058410031076 1.0 0.1908026588930638 3 P05067 1 +Extracellular matrix disassembly 0.7931283111174071 2.072496631015023 0.0382191501069977 1.0 0.1908026588930638 6 O75955,Q07954 2 +Positive regulation of interleukin 1 production 0.7938675479085324 2.07183794863841 0.0382805563500816 1.0 0.1909627753555797 7 P05067 1 +Ventricular septum morphogenesis 0.7891130457935311 2.0710650522002005 0.0383527172347668 1.0 0.1911762551288914 3 O94813 1 +Muscle structure development 0.458776328993908 2.069404224706368 0.0385081704070331 1.0 0.1916309575743456 98 P05556,Q99523,P98164,P14649,P21359,Q16539,P61586,P16989,P78310,P11413,Q7Z4V5,Q8IV08,P60660,P62942,P67809,P06493,Q16527,P41440,P58546,Q9H4M9,Q9BYT8,P09493,P10644,P19022,O75955,P31749,P17655,O75844 28 +Peptide cross linking 0.7872528769548345 2.0691475129120085 0.0385322463079598 1.0 0.1916309575743456 2 P04083 1 +Response to oxygen containing compound 0.3616757127002506 2.0660700174108433 0.0388218688028076 1.0 0.1927160525519708 274 Q99523,P04062,P05067,Q04656,P16278,Q06481,P08069,P11717,P02786,Q07954,Q5KU26,Q99538,Q8TBX8,Q8WTV0,P19021,O94813,P04083,P04114,P31751,O95251,Q86X55,Q99720,P00374,P09493,P31749,Q9UQB8,P17655,P40763,Q9BRK5,Q92572,Q92542 31 +Behavior 0.587466005661508 2.0618815154838126 0.0392190177776448 1.0 0.1942324090857462 80 P05556,O15118,P17900,P05067,Q13641,P04062,Q04656,P21359,Q99538,O43464,P54802,P50897,Q14671,P10253,P51790,P07686,O00264,Q9NWW5,P61160,Q14203,Q9HB07,P31749,P40763,P17655,O75915,Q92542 26 +Positive regulation of wound healing 0.7904069663100255 2.060152685080666 0.0393839465502143 1.0 0.1946566578402194 6 P04083,P05556,Q11206 3 +Response to hormone 0.3828154271124983 2.0595682475341315 0.0394398343468347 1.0 0.1946566578402194 183 P07858,Q99523,Q9P1Z2,O15118,P04062,Q15392,P16278,P98164,Q06481,P08069,Q8TBX8,P19021,O94813,P04083,P04114,P31751,P42785,Q86X55,Q16739,P31749,Q9UQB8,P40763,Q92572 23 +Transepithelial transport 0.7890652634057447 2.05925775852259 0.0394695527417956 1.0 0.1946566578402194 5 P51798,P78310 2 +Maternal placenta development 0.7896954950421822 2.056922966792548 0.0396936363836191 1.0 0.195317893316221 6 P07858 1 +Ovulation cycle 0.7910630358326645 2.0495214684370024 0.0404111507636004 1.0 0.1974162146957809 10 P04083,P19021,O94813,Q9UHI8 4 +Cytokine production 0.4649108865524213 2.0492159625878767 0.0404410018584708 1.0 0.1974162146957809 97 Q08722,O15111,P04062,P05067,Q06481,O75787,Q9Y624,P49591,P15311,Q16539,Q9Y5K6,P01889,Q07021,P04083,Q9BY67,Q8IV08,Q9UPY3,P04439,Q9NUD5,P41440,P06756,P26583,O75955,P40763,P17655 25 +Glycoprotein metabolic process 0.6442456776138371 2.048702664287975 0.0404911985292757 1.0 0.1974162146957809 70 O15118,Q04656,Q16706,Q9NRB3,Q9Y287,Q99805,O60512,Q86SF2,Q10472,Q8NCH0,Q7LGA3,Q9P2E5,Q9NX62,P15291,O43505,Q11206,O00462,Q8WVQ1,Q93063,O00754,Q10471,Q92542 22 +Negative regulation of leukocyte mediated immunity 0.7853942050319389 2.048340772824013 0.0405266205043608 1.0 0.1974162146957809 4 P01889 1 +Sphingolipid mediated signaling pathway 0.7840100153795276 2.0481569778030178 0.0405446204375206 1.0 0.1974162146957809 3 P31749 1 +Positive regulation of jnk cascade 0.7861527473494876 2.046078335974157 0.0407486640716436 1.0 0.1979768867926915 5 P05067 1 +Feeding behavior 0.7869267821905098 2.0401984735280028 0.0413305617354073 1.0 0.2001949084058795 7 P05067 1 +Actin filament based process 0.3815395182325547 2.03904778178529 0.041445258994345 1.0 0.2003033675227811 183 Q08722,Q96AC1,Q9NUQ9,P05556,Q69YQ0,Q15334,Q7L576,Q9UJU6,Q9UH99,Q14019,P14649,Q9Y3C0,P57737,Q9H2J4,O15511,Q13576,Q9Y624,Q07954,P21359,P15311,Q13308,Q9Y5K6,Q9UNF0,P67936,Q13464,P61586,P12814,O43293,P19021,P78310,Q14126,O94813,Q5T0N5,P35580,P04083,P60660,A0MZ66,Q68EM7,Q16527,Q16352,Q13136,P61160,P58546,Q9UM22,P52565,P09493,P43034,P10644,P11233,O00560,Q9UQB8,Q8N5W9,Q9UN37,Q9NVU7 54 +Prosthetic group metabolic process 0.7831030195596879 2.0380011360983374 0.0415498192539618 1.0 0.200659735417872 4 Q9Y697 1 +Positive regulation of response to wounding 0.7875011806135604 2.035868716992652 0.041763539872478 1.0 0.2015423606892751 9 P04083,P05556,Q04656,P08069,Q11206 5 +Eye photoreceptor cell development 0.7823032068601153 2.034389248694047 0.0419123650020976 1.0 0.2019611370567397 4 P54802 1 +Glandular epithelial cell development 0.7809738218233477 2.0283829987889708 0.0425211738939379 1.0 0.202010501197489 4 P31749 1 +Photoreceptor cell differentiation 0.7829844093446565 2.0264072024987256 0.0427230734824477 1.0 0.202010501197489 6 P54802,P40763 2 +Prostate gland development 0.7829404217332556 2.0262068855978375 0.0427435883352584 1.0 0.202010501197489 6 P07602 1 +Cellular homeostasis 0.3919525519494109 2.0240151335920795 0.0429685946512929 1.0 0.202010501197489 155 Q04656,P05067,O75503,P08069,P02786,Q92544,P51797,P50897,Q15904,P10253,Q93050,P61421,P51790,P13473,P62258,Q9Y487,Q7L0J3,P62942,P07686,Q9NWW5,Q8TAD4,Q9NQ11,Q9NWR8,P35670,Q9NUM4,Q9BWH2 26 +Bundle of his cell to purkinje myocyte communication 0.7786304604486293 2.023950535735073 0.042975241458548 1.0 0.202010501197489 3 Q14126,P15924 2 +Desmosome organization 0.7786304604486293 2.023950535735073 0.042975241458548 1.0 0.202010501197489 3 Q14126,P15924 2 +Triglyceride catabolic process 0.7766302744172116 2.021561395578952 0.0432216836250261 1.0 0.202864571304196 2 P04114 1 +Cardiac muscle cell cardiac muscle cell adhesion 0.7788603483909295 2.018826853398524 0.0435052189631886 1.0 0.2029672533665967 4 Q14126,P15924,P78310 3 +Regulation of heart rate by cardiac conduction 0.7788603483909216 2.01882685339849 0.0435052189631921 1.0 0.2029672533665967 4 Q14126,P15924,P62258 3 +Regulation of modification of synaptic structure 0.7801117463657545 2.0186872976451142 0.0435197310630159 1.0 0.2029672533665967 5 Q7L576,Q9UQB8,P61586 3 +Positive regulation of developmental process 0.3772429339916776 2.015883964622662 0.0438121107767632 1.0 0.2040177690677603 193 Q96AC1,P05556,Q7L576,Q9UJU6,Q13641,Q16706,P98164,Q96ST3,Q9H2J4,P08069,Q9NZ08,Q9Y624,P02786,P15311,Q16539,P61586,Q14444,P36896,Q07021,O94813,Q96HS1,P04083,P04114,Q9UPY3,O95251,A0MZ66,P06493,Q86X55,O96028,P55209,P61160,P39880,P41440,Q99829,Q9H4M9,P26583,O75955,P31749,Q9GZP4,Q9NUM4,O00560,Q9UQB8,P17655,P40763,Q9Y6C9 45 +Signaling receptor ligand precursor processing 0.7778422104204936 2.0142201006139273 0.0439864302285604 1.0 0.2041210734838221 4 P42892,Q8TAD4 2 +Macrophage differentiation 0.7791183279288368 2.0141758899329556 0.0439910700611063 1.0 0.2041210734838221 5 P05067 1 +Regulation of dna primase activity 0.7772378850862168 2.0114847353847485 0.0442742810645391 1.0 0.2052018639680479 4 Q9BRT9,Q9BRX5 2 +Regulation of neutrophil migration 0.7813638579699963 2.010948948491839 0.0443308493547893 1.0 0.2052587690609379 8 O94813 1 +Cerebellar cortex development 0.7839350305792716 2.010623980336502 0.0443651891451954 1.0 0.2052717706718 13 P58546,Q5KU26,Q04656,P04062,P54802 5 +Microtubule anchoring at microtubule organizing center 0.7791743960418057 2.009042114730149 0.0445326676004687 1.0 0.2057541987786027 6 Q9Y496,Q14203,Q8TD16,Q15154 4 +Positive regulation of circadian rhythm 0.773679551490118 2.0083028228258946 0.0446111221142837 1.0 0.2059232111355954 2 Q9Y297 1 +Macrophage activation 0.7786009183988787 2.006425808995013 0.0448108369941731 1.0 0.2065995388329085 6 P05067 1 +T cell activation involved in immune response 0.77925205536695 2.005098638368618 0.0449525030299444 1.0 0.2069595436527146 7 P04083,P40763 2 +Muscle cell cellular homeostasis 0.7789137794283381 2.003548807671484 0.0451184143007603 1.0 0.2074299979505296 7 P10253 1 +Lytic vacuole organization 0.7752439449988466 1.997196187671034 0.0458038750473313 1.0 0.2089676617365141 27 Q14108,P11117,P07686,O75503,P54802,O14773,Q9NWW5,P50897,P10253 9 +Bone remodeling 0.7783491194184236 1.9970810304937283 0.0458163812569623 1.0 0.2089676617365141 8 P21359,O14773,P02786 3 +Regulation of vascular associated smooth muscle contraction 0.7710239008557134 1.9963552793482304 0.0458952649240829 1.0 0.2090819976597479 2 P61586 1 +Regulation of immune response 0.3960923637015926 1.9949519560863196 0.0460481200635978 1.0 0.2096316514783369 120 Q08722,Q06481,Q9NZ08,P02786,Q5KU26,Q16539,P28070,P01889,Q14671,Q07021,Q9NPR9,Q8TCT8,Q9BY67,P04083,P11279,P62942,O15400,O96028,P04439,Q7Z739,Q9NUD5,O75955 22 +Cellular response to exogenous dsrna 0.7775755720442216 1.993519714479917 0.046204566966101 1.0 0.2101968769736674 8 Q9NUD5,Q5KU26,O75955,P41440 4 +Trophoblast cell migration 0.7723632349916971 1.9893938365349673 0.0466577494225135 1.0 0.2113722677387357 4 P36896,Q07021 2 +Positive regulation of neural precursor cell proliferation 0.7740690723443959 1.9857274838481571 0.0470635915516313 1.0 0.2124675868326959 6 P98164 1 +Substrate dependent cell migration cell extension 0.7714275714378903 1.9851481864409384 0.0471279870025211 1.0 0.2124675868326959 4 O00560,A0MZ66 2 +Cardiac muscle cell proliferation 0.7725359298229734 1.9842332339100544 0.0472298452715269 1.0 0.2126322909527251 5 P10644,Q16539,Q8NDZ4 3 +Regulation of brown fat cell differentiation 0.7695980425109095 1.9831768638381464 0.047347677258793 1.0 0.2126619666888655 3 Q16539 1 +Viral process 0.3915911335277846 1.9818596781126172 0.0474949479345494 1.0 0.2126619666888655 144 P05556,P07858,P08195,O15118,Q16706,P11717,Q9Y624,P02786,Q9Y3E7,Q14108,Q8WTV0,Q10472,P78310,Q9UNP9,P11279,P56545,P27105,Q00403,Q11206,P06756,P46934,Q9UN37,Q6UWE0 23 +Cerebellar purkinje cell layer morphogenesis 0.7689867445716827 1.980411515433205 0.0476573070576233 1.0 0.2126619666888655 3 P04062 1 +Copper ion homeostasis 0.7730880931193339 1.9768219461497736 0.0480617600937118 1.0 0.2138785984974072 7 P35670,P05067 2 +Regulation of mononuclear cell migration 0.776898830702622 1.9753180246625448 0.0482320690075046 1.0 0.2141819708314156 16 Q08722,Q99538,P05067,P31749,O94813 5 +Positive regulation of camp dependent protein kinase activity 0.766007671879614 1.9737495898620527 0.0484102233959489 1.0 0.2145340737288137 2 P23634 1 +Establishment of epithelial cell apical basal polarity 0.770031229031297 1.972816897341645 0.0485164273095026 1.0 0.2146653957595546 5 P15311,Q13308,P61586 3 +Oxidative rna demethylation 0.7654175272941786 1.971086836214727 0.0487139441690513 1.0 0.2147132290383147 2 Q9C0B1 1 +Oxidative demethylation 0.7654175272941786 1.971086836214727 0.0487139441690513 1.0 0.2147132290383147 2 Q9C0B1 1 +Regulation of lipase activity 0.7755305077477991 1.9710819164894928 0.0487145068033165 1.0 0.2147132290383147 13 Q99523,P50897,Q07954 3 +Striated muscle cell proliferation 0.7693126046216563 1.9639591026626708 0.0495348348897639 1.0 0.2173028677720339 6 P10644,Q16539,Q8NDZ4 3 +Establishment of planar polarity involved in neural tube closure 0.7636470935379177 1.9630944745626884 0.0496351974752982 1.0 0.2173028677720339 2 Q13308 1 +I kappab phosphorylation 0.76635154959695 1.962085101948305 0.0497525771393281 1.0 0.2173028677720339 4 O15111,P31749 2 +Interleukin 10 production 0.7663379514663651 1.962023250075441 0.0497597774396183 1.0 0.2173028677720339 4 Q08722 1 +Positive regulation of fat cell differentiation 0.7697808767749008 1.9616189923740384 0.0498068594112703 1.0 0.2173028677720339 7 Q86X55,P31749 2 +Establishment of planar polarity of embryonic epithelium 0.7638724911452177 1.9572471456254907 0.0503184183102916 1.0 0.2182585420938527 3 P43034,Q13308 2 +Neuron projection guidance 0.7714534997918575 1.957203790810177 0.0503235133153414 1.0 0.2182585420938527 22 P42892,P05067,Q92859,O94813 4 +Negative regulation of lipid metabolic process 0.771021114917042 1.9565569055316532 0.0503995858519366 1.0 0.2183132135905189 10 Q06481,P31749 2 +Positive regulation of phagocytosis 0.7703357900063708 1.9565262868206752 0.0504031889441705 1.0 0.2183132135905189 9 Q06481,Q08431 2 +Response to nerve growth factor 0.7714509465005772 1.95586570439318 0.0504809763254683 1.0 0.2185047578981375 11 Q99523,P05067 2 +Cellular extravasation 0.7671252669029753 1.9539334953174987 0.0507090827033209 1.0 0.2192006164665468 6 Q08722,Q9Y624,Q11206 3 +Mating 0.7669938757613285 1.9533309664295748 0.0507803904416992 1.0 0.2193631995855753 6 P05067 1 +Carbohydrate derivative biosynthetic process 0.3804917749941392 1.952122372138824 0.0509236776858919 1.0 0.2196906174520584 172 O15118,Q04656,Q16706,Q9NRB3,Q9Y287,Q9UMR5,Q99805,O60512,Q86SF2,P06865,Q10472,P50897,Q8NCH0,Q7LGA3,Q8NBZ7,Q9P2E5,P15291,O43505,Q11206,Q8WVQ1,Q16739,Q93063,Q10471,Q92542 24 +Membrane invagination 0.7717314253921457 1.9506044051571572 0.0511041227876569 1.0 0.2203230724156601 16 Q06481,Q08431 2 +Hippo signaling 0.7635345160587754 1.9492639110305032 0.0512639160425756 1.0 0.220719638516645 4 Q16539 1 +Regulation of anion transmembrane transport 0.7654323539450849 1.9461675903345963 0.0516346116474759 1.0 0.2218754599505402 6 P08183,P05556,Q15041 3 +Sphingoid metabolic process 0.7635151206666922 1.9430586108392465 0.0520090770916783 1.0 0.2231899089431945 5 Q13510 1 +Positive regulation of chemotaxis 0.7699123871504058 1.941945903007596 0.0521436495924367 1.0 0.2234727839675861 17 Q99538,Q07021,Q13641,O94813 4 +Cell growth 0.4468789070014446 1.937532766837373 0.0526802519925766 1.0 0.2254756347611268 98 Q15375,P05556,O75414,Q7L576,P05067,Q9UJU6,Q96ST3,P02786,O43909,P61586,P50897,P11413,P36896,Q7Z4V5,O94813,Q9Y263,O95251,A0MZ66,Q6IAA8,O43598,Q9BTE7,P58546,Q99829,O75489,P43034,P31749,Q5BJF2,O00560 28 +Steroid catabolic process 0.7608277843762742 1.936930113396138 0.0527538868242278 1.0 0.2256424462718288 4 Q8WTV0 1 +Regulation of long term neuronal synaptic plasticity 0.7629802284952181 1.9349089623284457 0.0530014682077104 1.0 0.2264039094699443 6 P05067 1 +Chondrocyte differentiation 0.7655054009430053 1.9340921405064937 0.053101800090102 1.0 0.2264527304217248 9 Q92896,Q8N5W9,Q9NX62 3 +Cardiac chamber morphogenesis 0.7667149643058035 1.9336836221679816 0.0531520387226414 1.0 0.2264527304217248 11 P09493,P62942,P98164,Q9UHI8,O94813 5 +Pinocytosis 0.7649756176516773 1.9316288103253152 0.0534053372303111 1.0 0.2272344740975984 9 Q06481,P50897 2 +Response to copper ion 0.7653915507873315 1.9302978228419845 0.053569946663794 1.0 0.2274888145996731 10 P35670,P05067,P19021,P02786 4 +Cholesterol efflux 0.7639285046496458 1.9267584249166871 0.0540097429432591 1.0 0.2280672628905279 9 P04114,O15118,Q8WTV0,P61916,Q07954 5 +Photoreceptor cell development 0.7597120362417981 1.925651917177727 0.0541478514640538 1.0 0.2280672628905279 5 P54802 1 +Regulation of mitochondrial atp synthesis coupled electron transport 0.7568951345342455 1.925561617224753 0.0541591352280383 1.0 0.2280672628905279 3 Q9H3K2 1 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.7550899970492793 1.9243786203736943 0.0543071422958534 1.0 0.2280672628905279 2 P23396 1 +Membrane to membrane docking 0.7561939285877253 1.922372087752624 0.0545589551504577 1.0 0.2287049568766772 3 P15311 1 +Ventricular septum development 0.7620838663119327 1.921945660068436 0.0546125956352163 1.0 0.2287824952286091 8 P98164,O94813 2 +Positive regulation of megakaryocyte differentiation 0.7560053149062427 1.921513991365016 0.0546669401840202 1.0 0.2288628814134869 3 Q9GZP4 1 +Regulation of cellular ph 0.7641074599244354 1.9209217694503984 0.0547415708156879 1.0 0.2290280372815737 22 P61421,P51790,Q9Y487,Q92544,O75503,Q9NUM4,Q9NWW5,P50897,Q15904,Q93050 10 +Microtubule anchoring at centrosome 0.7584707793645666 1.919964605323532 0.054862370371707 1.0 0.2292387876250403 5 Q9Y496,Q14203,Q15154 3 +Cell migration involved in sprouting angiogenesis 0.7615274519467364 1.9193661038953287 0.0549380175440878 1.0 0.2294076293855113 8 P04083,P05556,P31749,Q5JRA6,O94813 5 +Viral protein processing 0.7621376954032182 1.9184239161455887 0.0550572809189011 1.0 0.229438351361702 9 Q10472,Q11206 2 +Negative regulation of transcription regulatory region dna binding 0.75361463558572 1.9176891668660017 0.0551504361808299 1.0 0.229438351361702 2 Q96ST3 1 +Negative regulation of neural precursor cell proliferation 0.7591124435894238 1.9171266335419357 0.0552218457962387 1.0 0.2295620792678892 6 Q06481 1 +Positive regulation of interleukin 6 production 0.7597623984309655 1.9111792521638709 0.0559815492208592 1.0 0.2316846061206573 8 P05067 1 +Positive regulation of transport 0.3731114459917481 1.9107086290569884 0.0560420352778634 1.0 0.2317679231453494 185 Q08722,P05556,Q9UQ16,P54709,Q06481,P08183,O00410,Q08431,Q07954,Q12907,Q9Y6B6,P15311,O95071,Q16539,Q9Y5K6,O43464,Q92544,P19784,Q92783,P50897,P55786,P11413,P04083,P31751,P62258,Q9NV96,P11279,Q9Y282,P06493,P27105,P41440,Q9NQ11,Q9H4M9,O95486,P46934,P19022,Q15041,O75955,P31749,Q96GC9,O00560,Q9UN37,Q05D32 43 +Galactose metabolic process 0.7550311670063443 1.9104687627434305 0.0560728846319393 1.0 0.2317679231453494 4 P16278 1 +Copper ion transport 0.7547563729800821 1.9092127292685712 0.0562346548598933 1.0 0.2321417901952476 4 P35670 1 +Negative regulation of immune effector process 0.7593693245035733 1.905527413166591 0.0567115475167898 1.0 0.2333705273920998 9 Q08722,P04083,P01889 3 +Mononuclear cell migration 0.7603304433021127 1.905038443145879 0.0567750740926389 1.0 0.2334843539754134 23 Q08722,Q99538,P04062,P05067,P31749,Q07021,Q9Y624,O94813 8 +T cell mediated cytotoxicity 0.7574952072993723 1.9006544361816895 0.0573472902839706 1.0 0.2347363945606138 8 O15400,Q9BY67,P01889,P53634 4 +Negative regulation of smooth muscle cell migration 0.7565470451906687 1.9005684272634835 0.057358564267536 1.0 0.2347363945606138 7 O94813,Q07954 2 +Tetrahydrobiopterin metabolic process 0.7522351289680232 1.89768183016062 0.0577380075147271 1.0 0.2358057897872481 4 P61457,P00374 2 +Pentose metabolic process 0.7531447042425136 1.8955273369277448 0.0580225735944126 1.0 0.2359931641052523 5 Q8NBZ7 1 +Regulation of protein lipidation 0.7502951593860524 1.895503394258384 0.0580257424851224 1.0 0.2359931641052523 3 P04062,Q9H2M9 2 +Regulation of actin cytoskeleton reorganization 0.7569105147479916 1.8940604728356785 0.0582169835376382 1.0 0.2359931641052523 9 Q9Y5K6,P52565,O43293,Q9UQB8,Q13576,Q9Y624 6 +Non canonical wnt signaling pathway 0.7540017612415661 1.8935855866431963 0.0582800381376702 1.0 0.2359931641052523 6 Q93074,Q8TAA9,Q13308,P61586 4 +Heterotypic cell cell adhesion 0.7581483814410299 1.893446660117355 0.0582984952944569 1.0 0.2359931641052523 11 Q08722,P41440,P05556,P06756,Q14254,O75955,P15924,P78310,Q14126 9 +Regulation of fibroblast migration 0.7574624488017495 1.893206155894898 0.0583304590894671 1.0 0.2359931641052523 10 P05556,Q06481,P31749 3 +Muscle organ morphogenesis 0.7526306178366593 1.8931657095782048 0.0583358359665655 1.0 0.2359931641052523 5 P98164,P09493 2 +Cardiac muscle tissue morphogenesis 0.7526306178366593 1.8931657095782048 0.0583358359665655 1.0 0.2359931641052523 5 P98164,P09493 2 +Ventricular cardiac muscle tissue morphogenesis 0.7526306178366593 1.8931657095782048 0.0583358359665655 1.0 0.2359931641052523 5 P98164,P09493 2 +Regulation of nuclear cell cycle dna replication 0.7495066017001619 1.891906511081011 0.0585034381201756 1.0 0.236263884716094 3 O95785 1 +Regulation of lipoprotein metabolic process 0.750516681429013 1.8898155650519275 0.0587826311126278 1.0 0.2372442210435258 4 P06756,P04062,Q9H2M9 3 +Negative regulation of vascular associated smooth muscle cell migration 0.7486440096584596 1.8879705815932324 0.0590298999317391 1.0 0.2374323501223147 3 P09493 1 +Negative regulation of myosin light chain phosphatase activity 0.7459427559752159 1.8828370672236316 0.0597224520026844 1.0 0.2383771689377533 2 Q13464 1 +Negative regulation of bicellular tight junction assembly 0.7459427559752159 1.8828370672236316 0.0597224520026844 1.0 0.2383771689377533 2 Q13464 1 +Positive regulation of membrane potential 0.7524172440497081 1.8814470895397664 0.059911126335431 1.0 0.2386912071258605 7 P31749 1 +Lymphocyte migration 0.7541690370517456 1.8747068253586308 0.0608330674009844 1.0 0.241183476723757 11 Q9Y624,P04062,P05067,P31749 4 +Positive regulation of muscle tissue development 0.7463485859970452 1.870712686942421 0.0613849153578307 1.0 0.2420446995635846 4 O75955 1 +Positive regulation of skeletal muscle tissue development 0.7463485859970452 1.870712686942421 0.0613849153578307 1.0 0.2420446995635846 4 O75955 1 +Cerebellar cortex formation 0.7485322562401046 1.868336329370655 0.0617152058192598 1.0 0.2430526254587909 6 Q04656,P04062 2 +Regulation of protein catabolic process 0.3865457738638508 1.8677497851966376 0.0617969556904716 1.0 0.2432274374516143 127 O95816,P04062,Q13190,P98164,Q9H2J4,Q9H4H8,Q07954,P15311,Q96HY6,Q13620,P19784,Q9Y4X5,P53634,P53350,P10619,Q96KB5,Q9UNN5,Q9NQ11,P46934,Q9GZU8,P31749,Q9GZP4,P46379,O00560 24 +Cellular response to mineralocorticoid stimulus 0.7455805734452831 1.8671892227941032 0.0618751680805385 1.0 0.2432411498818271 4 P08069,O95831 2 +Regulation of dna dependent dna replication initiation 0.745110606770659 1.865032578887271 0.062176837785548 1.0 0.2438380807132035 4 O95251 1 +Regulation of lymphocyte migration 0.748702054152083 1.8642176126281125 0.0622911509861099 1.0 0.244139309403718 7 P05067,P31749 2 +Cellular macromolecule localization 0.3311444657300225 1.862988419038044 0.0624638956060001 1.0 0.244470257040315 572 Q96AC1,Q99523,Q10713,P56589,P54709,Q13641,Q96ST3,Q06481,O14773,P23634,O00410,Q9P258,P02786,Q07954,Q8TEX9,P15311,O95071,Q96HY6,Q9Y5K6,Q14108,Q9HAS0,Q9H3S7,Q15904,P10619,P13473,P11279,P52789,Q6IAA8,P27105,Q8WUX9,Q8NFH5,Q13136,Q8N3R9,Q9BUR4,Q9NQ11,Q8NCM8,P31749,Q9P0I2,P11233,Q9UBF2,Q99747,Q92688,Q9BRG1,Q9UL25,Q05D32,Q15154,Q8N4H5,Q9H1Z9,Q8TD16,Q15629,Q15334,Q86VS8,Q14254,O15118,P63104,Q13190,Q9BUN8,Q9H173,Q9ULT8,O43752,Q9Y624,Q99805,P46060,P24390,P21359,O60830,Q9Y6B6,P68036,Q9UNF0,Q9P2S5,Q92544,Q13464,P05026,Q96D46,Q9H2M9,Q15070,Q9BXS5,Q9HD45,Q96C92,P35606,Q96DY7,P31751,P60953,Q9NV96,Q15006,O43731,O14777,P67809,O95251,P60520,O15260,P60604,O75381,O15400,P43307,Q16181,Q9UI26,Q9UPT5,Q9Y512,Q5JRX3,O15078,O15344,Q15041,O94979,O14657,P14923,P15927,O00560,P40763,Q9BW27,Q9UN37,Q96RT1,Q6UWE0,Q92572,Q96ES7,Q13277,Q9H223,Q9H4H8,Q16539,Q9NQX3,P20645,P55786,P84085,Q99595,P51858,P62258,Q9Y282,P40855,Q86Y82,Q14168,Q5JRA6,Q9H4M9,P46934,P19022,O75955,P46379,P31946,Q9Y6C9,O95831,Q4J6C6,P05556,Q8TAG9,Q9UH99,Q8NEY8,O15027,Q9H490,O43464,P19784,Q92783,Q15555,P53350,O43292,P06493,O00264,Q9ULC3,P41440,Q04917,O95486,O75915 159 +Epithelium development 0.3743521099301265 1.8628153472091555 0.062488250033039 1.0 0.244470257040315 173 Q15375,P07858,P07602,P98164,P42892,O14773,Q9Y624,P21359,Q93074,P36896,O94813,P04083,P31751,Q13510,P15291,O43598,Q9UDY2,P31749,Q13572 19 +Chloride transport 0.7514745979411215 1.862000555865705 0.0626030118801974 1.0 0.2444894181063943 11 Q9H813,Q9UHG3,P51790,Q9C0H2,P51798,P51797 6 +Amyloid beta clearance 0.7509887557357345 1.859707965282201 0.0629268544860908 1.0 0.2454486654909833 11 P98164,Q07954 2 +Antigen processing and presentation 0.7502456056967028 1.8577877207590097 0.0631991655595658 1.0 0.2460928126631094 24 P10321,Q9Y6B6,Q6P179,Q99538,Q9UIQ6,P04062,P01889,P04439 8 +Response to thyroid hormone 0.7469476254331009 1.8560722337327131 0.0634432628255612 1.0 0.2460928126631094 7 P07858 1 +Ceramide metabolic process 0.7498334749699692 1.8557157628163783 0.0634940828291901 1.0 0.2460928126631094 24 Q8NCC3,Q99519,O60512,P06280,P06865,P17900,P04062,Q13510,P07686,Q9NWW5,Q99805 11 +Interleukin 6 production 0.7515318695097022 1.8556194271397248 0.0635078226227379 1.0 0.2460928126631094 14 Q08722,P04062,P05067,P01889,P17655 5 +Collateral sprouting 0.7427695854348484 1.8542836492074073 0.0636985901107607 1.0 0.2466004471633829 4 P05067 1 +Natural killer cell activation 0.746538470879591 1.854171797146369 0.0637145855804623 1.0 0.2466004471633829 7 P11279,O95251 2 +Smooth muscle cell migration 0.7507336719053869 1.8535827705689167 0.0637988744225293 1.0 0.2467799598875019 13 O15511,P09493,Q04656,Q96N67,Q13685,Q9UHI8,O94813,Q07954 8 +Cd4 positive alpha beta t cell activation 0.7463304868340324 1.8532056346109744 0.0638528903729047 1.0 0.2468229400217687 7 P04083,P40763 2 +Establishment of golgi localization 0.7402597402597385 1.8496410674122257 0.0643652996335495 1.0 0.2478628568425337 3 P63104,P60953 2 +Positive regulation of leukocyte migration 0.7483590506532691 1.83905641799654 0.0659068883198028 1.0 0.2526818863144385 15 Q08722,Q99538,Q07021,P05067 4 +Regulation of ph 0.7469357359821172 1.838143902402716 0.066041203432936 1.0 0.2530038970641631 23 P61421,P51790,Q9Y487,Q92544,O75503,Q9NUM4,Q9NWW5,P50897,Q15904,Q93050 10 +Response to camp 0.7443697241098957 1.835394452153446 0.066447265146152 1.0 0.2540056935416617 9 P05067 1 +Glycosphingolipid biosynthetic process 0.7381141194760632 1.8328776071811632 0.0668207745510238 1.0 0.2548349398518836 4 Q99805,O60512 2 +Regulation of tissue remodeling 0.7417781312988749 1.8320380229246236 0.0669457559266564 1.0 0.2550127975907157 7 P02786 1 +Golgi localization 0.7389435231635533 1.8301061844876385 0.0672340623473466 1.0 0.2554354170224403 5 P63104,Q86VS8,P60953 3 +Bone morphogenesis 0.7422966272412885 1.8298450443780288 0.067273113030132 1.0 0.2554354170224403 8 Q92896,Q9NX62 2 +Negative regulation of biomineralization 0.7387777802355038 1.829340433730751 0.0673486249870338 1.0 0.2554354170224403 5 Q6W2J9,Q13464,Q8N5W9 3 +Maintenance of synapse structure 0.7387320751084474 1.8291292620975503 0.0673802462514112 1.0 0.2554354170224403 5 Q9BRK5,P56545,Q14203 3 +Water homeostasis 0.7420451765996376 1.828669891292498 0.0674490755547734 1.0 0.2554354170224403 8 Q93063,P04062 2 +Positive regulation of carbohydrate metabolic process 0.7415565054521966 1.826385754563363 0.0677921761268023 1.0 0.2555454931010325 8 P05067,P31749 2 +Positive regulation of inflammatory response 0.7432175659472433 1.822976262048656 0.0683069862403686 1.0 0.2573370835791667 11 P53634,P05067 2 +Transmembrane transport 0.3546679104519582 1.821714579339389 0.0684983046254141 1.0 0.2579085963628955 235 P05556,Q99523,P08195,Q9UBX3,Q9C0H2,P30825,Q14728,P04062,P05067,Q04656,Q7KZN9,P98164,Q06481,P08183,P07384,Q9H2J7,O60830,Q6NT16,Q16539,Q8WTV0,Q13423,P51797,Q8NB49,Q70HW3,P11413,Q99595,P31751,P51790,Q9NV96,P62258,P61421,Q7L0J3,P62942,Q8IXU6,P00403,Q6P4A7,Q8TAD4,P27105,Q9P2B4,P41440,Q9UHG3,Q9NQ11,Q9NWR8,P35670,P06756,P46934,Q15041,P31749,Q04917,P51798,Q96GC9,O75915,O95831 53 +Positive regulation of systemic arterial blood pressure 0.7320743582177602 1.8195557753583815 0.0688266816807714 1.0 0.2585468538614517 2 P61586 1 +Negative regulation of sodium ion transport 0.7320743582177439 1.8195557753583071 0.0688266816807827 1.0 0.2585468538614517 2 P46934 1 +Cardiac ventricle morphogenesis 0.7368858274442446 1.8143851473246897 0.0696184507887633 1.0 0.2608925309384737 6 P98164,P09493 2 +Positive regulation of potassium ion import across plasma membrane 0.732290436835884 1.813088121912415 0.0698182308954673 1.0 0.2610664463696108 3 P54709,P05026 2 +Regulation of natural killer cell mediated immunity 0.7365146469808566 1.8126615719230357 0.0698840348955394 1.0 0.2611624955051443 6 P11279,Q9BY67,P01889 3 +Regulation of phospholipase activity 0.740193237647888 1.8120026768342987 0.0699857828935253 1.0 0.2613926830962993 10 P50897,Q07954 2 +Associative learning 0.7412502515619336 1.808327993867868 0.0705554674499979 1.0 0.2627611690014423 13 P21359,P05556,Q99538,P05067,Q13641,P50897,P61160 7 +Peripheral nervous system myelin maintenance 0.7325666669511982 1.807318344310551 0.0707126574107448 1.0 0.2627611690014423 4 P31749 1 +Regulation of heterotypic cell cell adhesion 0.7325066430469597 1.807041486150953 0.0707558109461641 1.0 0.2627611690014423 4 Q14254,P41440,O75955 3 +Columnar cuboidal epithelial cell development 0.7337106421227771 1.805905504948136 0.0709331010820408 1.0 0.2629695262210057 5 P31749 1 +Protein o linked mannosylation 0.7320961608042593 1.805147977465965 0.0710515290738249 1.0 0.2632586535404669 4 O43505 1 +Small rna loading onto risc 0.7333377068729787 1.804178883429794 0.0712032685896071 1.0 0.2634279666374496 5 Q5KU26 1 +Protein targeting to lysosome 0.739667357128313 1.8007579176163877 0.0717410444023076 1.0 0.2644348928302976 13 Q99523,P13473,Q14108,P20645,Q9UN37 5 +Regulation of leukocyte migration 0.7365899082016063 1.800284006340357 0.0718158049960009 1.0 0.2644348928302976 27 Q08722,Q99538,P05067,P31749,Q11206,Q07021,O94813 7 +Cardiac septum development 0.7382263564544788 1.799324814207836 0.0719673150789921 1.0 0.2648429740894509 11 P98164,O94813 2 +T cell selection 0.7291825779207008 1.7988020570561418 0.0720499978351276 1.0 0.2649689878316362 3 P40763 1 +Muscle cell migration 0.7395278793119145 1.7964855139935856 0.0724173345294416 1.0 0.2657479412551664 15 P04083,O15511,P09493,Q04656,Q96N67,Q13685,Q9UHI8,O94813,Q07954 9 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.7301342237672535 1.796093607248486 0.07247963098214 1.0 0.2657701891918578 4 Q92783,Q9BRG1 2 +Ventricular cardiac muscle tissue development 0.7332395757337016 1.7922323740417092 0.0730957508297356 1.0 0.2671832329598983 7 P98164,Q14126,P09493,P62942 4 +Positive regulation of nuclease activity 0.7306339541410708 1.791653536797991 0.0731884815896422 1.0 0.2672049810553085 5 P26583,P31749 2 +Response to insecticide 0.7249926231926809 1.787106972652482 0.0739202007573456 1.0 0.2691389859789261 2 P36551 1 +Negative regulation of response to stimulus 0.3501030765836341 1.7843990149235391 0.0743588510356212 1.0 0.2700300341887164 247 Q08722,P05556,Q10713,O60313,P04062,Q13641,P98164,Q06481,P23634,P08069,Q07954,P21359,Q9UJ14,P15311,O95071,Q96HY6,Q9Y5K6,Q99538,P28070,Q16539,Q99471,Q8TBX8,O43464,P61586,P19784,P16989,Q9Y4E8,P01889,Q92896,Q07021,Q8N183,O94813,Q9NPR9,P04083,Q9H3F6,P23229,Q96KB5,Q9Y297,Q96S59,Q9UBB9,Q9H3K2,P62942,P67809,P13693,P04439,Q7Z739,Q96G23,Q99829,P06756,P46934,P19022,P26583,P31749,P31946,Q9BRG1,P80303,Q05D32 57 +Amino acid import 0.7325315705655097 1.7841229318048006 0.074403691771935 1.0 0.2700300341887164 8 P05556,P30825,Q15041,P08195 4 +Positive regulation of intracellular signal transduction 0.3781832381293485 1.784060673545751 0.074413806656614 1.0 0.2700300341887164 142 Q96AC1,P05556,O15111,P18615,P05067,Q13641,P98164,P08069,Q9Y624,P02786,Q9Y4E8,Q14671,Q07021,Q15555,P62942,O14777,O43567,Q9NUD5,Q8WVQ1,Q99829,P06756,P46934,P19022,O00560,O75915 25 +Ventral spinal cord development 0.7273173466603202 1.7830816784968009 0.0745730084040579 1.0 0.2703119227617277 4 Q14203,Q8NCM8 2 +Snrna transcription by rna polymerase iii 0.7241074063145478 1.7830446111235627 0.07457904167141 1.0 0.2703119227617277 2 Q659A1 1 +Regulation of leukocyte mediated cytotoxicity 0.7321446005806035 1.7823074944034034 0.0746991012363054 1.0 0.2703119227617277 8 P11279,O15400,Q9BY67,P01889 4 +Positive regulation of cell killing 0.7321446005806035 1.7823074944034034 0.0746991012363054 1.0 0.2703119227617277 8 P11279,O15400,Q9BY67,P01889 4 +Negative regulation of protein import into nucleus 0.7265212166743921 1.7794015896310835 0.0751739460467106 1.0 0.2711917626977936 4 P21359 1 +Cell junction maintenance 0.7292640522974045 1.7736540669694243 0.0761203885783607 1.0 0.2737475046906484 7 Q9BRK5,Q96AC1,P56545,Q14203 4 +Regulation of establishment of planar polarity 0.7292217899234066 1.7734564166328148 0.0761531076796873 1.0 0.2737475046906484 7 Q8TAA9,P60953,Q13308,Q93074,P61586 5 +Regulation of cell killing 0.7310907649538544 1.7729552567801874 0.0762361212687003 1.0 0.273894674094503 9 P11279,O15400,Q9BY67,P01889 4 +Negative regulation of fat cell differentiation 0.7276658676911538 1.771498861367757 0.076477781860492 1.0 0.2745868884219304 6 Q99523 1 +Regulation of granulocyte chemotaxis 0.7307366974417293 1.7712860177200749 0.0765131513974473 1.0 0.2745868884219304 9 O94813 1 +Membrane protein intracellular domain proteolysis 0.7225528340785995 1.7682694423061944 0.0770158698852125 1.0 0.276086626075294 3 Q8TCT8 1 +Regulation of neuron projection regeneration 0.7255008636927868 1.7678383344900552 0.0770879342445878 1.0 0.2761750382809852 5 Q96G23,P08069 2 +Regulation of protein localization to cell surface 0.7308940598119656 1.764497071166816 0.0776483280221844 1.0 0.2768682307353641 11 P31749,Q92544 2 +Cellular monovalent inorganic cation homeostasis 0.7294229859141217 1.7593078381322869 0.0785252360067849 1.0 0.2790389117926692 26 P61421,P51790,Q9Y487,Q92544,O75503,Q9NUM4,Q9NWW5,P50897,Q15904,Q93050 10 +Vesicle organization 0.3923293794795421 1.7579455645444728 0.0787567719700863 1.0 0.2796469181333672 103 Q13277,Q99523,Q13190,Q5SQN1,O43752,O15027,Q9Y6B6,Q9Y3E7,Q14108,P04083,P31751,P51790,Q86Y82,Q5JRA6,O15400,Q9NQ11,O00560,Q9BRG1,Q9UN37 19 +Regulation of membrane tubulation 0.718501032753023 1.7572845523899747 0.0788693194938887 1.0 0.2798034168420794 2 Q9Y371 1 +Glial cell development 0.7309142522993816 1.755586229003336 0.0791590853074566 1.0 0.2805256643176607 22 P21359,Q93074,P05067,P31749,Q92542,Q07954 6 +Negative regulation of leukocyte migration 0.7253261747036471 1.7552241221828266 0.0792209793694493 1.0 0.2805922609875492 7 O94813,P31749 2 +Regulation of fatty acid transport 0.7238922885961743 1.7539027668077631 0.079447169435546 1.0 0.2810023647409827 6 P31749 1 +Substrate dependent cell migration 0.7250202877089487 1.7537913829421272 0.0794662601364284 1.0 0.2810023647409827 7 O00560,O94813,A0MZ66 3 +Myotube differentiation 0.7308308777698461 1.7522544933136412 0.0797300571902095 1.0 0.2813779935832877 17 P05556,Q8IV08,Q99523,Q16539,Q9H4M9,Q9BYT8,O75955,P17655 8 +Positive regulation of potassium ion transmembrane transporter activity 0.718713105076733 1.7505508821243327 0.080023302272044 1.0 0.2814433807622942 3 P54709,P05026 2 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.720671469544679 1.7453900771092232 0.0809169917605117 1.0 0.28364376528681 5 P42892,P09493,O75787 3 +Production of molecular mediator involved in inflammatory response 0.7279707323545074 1.7446771910913597 0.0810410757962314 1.0 0.28364376528681 13 Q06481,Q8IV08,P40763 3 +Regulation of vascular permeability 0.7228705073281152 1.743717484723318 0.08120836497428 1.0 0.2837705277349545 7 Q9UDY2,O94813 2 +Cellular response to testosterone stimulus 0.7171226538449775 1.7432042774317231 0.0812979385702352 1.0 0.2837705277349545 3 P08069 1 +Programmed cell death 0.3315723067492734 1.7423635106628712 0.0814448566501895 1.0 0.2839882253844316 424 P07858,Q99523,Q04446,O60313,P05067,Q15392,P98164,Q96ST3,P11717,P02786,Q13619,P30154,Q96HY6,Q99538,Q9UHI6,P61586,P33993,P16989,P50897,P53634,O94813,Q9BY67,P11279,Q13510,Q99720,P31749,Q13572,P17655,Q92542,Q15375,P04062,P21359,P36896,Q07021,P04083,P31751,P15291,Q8NDZ4,Q9NXR7,Q01105,Q15041,Q9H2J4,P08069,Q8ND90,Q16539,O43293,P23229,P51858,Q9H3K2,P06756,P46379,O60934,Q9Y6C9,O95831,P05556,O75414,Q14728,Q9C0C9,Q13564,Q9Y3E7,O43464,P19784,Q9BTT0,P11413,Q8IXB1,Q96HS1,P53350,Q13144,Q9UPY3,Q9BX68,P13693,P06493,O60333,Q7L5Y9,Q9UNN5,Q9H8M7,P26583,P11234,O75915,O75844 80 +T cell migration 0.7232106750350256 1.7403210947599772 0.0818026519895809 1.0 0.2849456731456158 8 P05067 1 +Synaptic vesicle priming 0.7195768479908659 1.740296413024199 0.0818069835805155 1.0 0.2849456731456158 5 Q7L0J3 1 +Cellular iron ion homeostasis 0.7261559272350305 1.7387267629766343 0.082082836147884 1.0 0.2854282863434236 12 Q15904,P61421,Q9NQ11,P02786 4 +Histone h4 r3 methylation 0.7143700206550598 1.7382688408019809 0.082163454039625 1.0 0.2854282863434236 2 O14744 1 +Positive regulation of smooth muscle cell proliferation 0.725186231803101 1.737318820635838 0.0823309113132955 1.0 0.2855844696809802 11 P31749,Q9UHI8 2 +Acid secretion 0.715758997846806 1.7369018599350976 0.0824044950821345 1.0 0.2855844696809802 3 Q7L0J3 1 +Gamma aminobutyric acid transport 0.715758997846806 1.7369018599350976 0.0824044950821345 1.0 0.2855844696809802 3 Q7L0J3 1 +Gamma aminobutyric acid secretion 0.715758997846806 1.7369018599350976 0.0824044950821345 1.0 0.2855844696809802 3 Q7L0J3 1 +Regulation of water loss via skin 0.7184421202106186 1.7350139645341824 0.0827383317827048 1.0 0.2863511642240343 5 P04062 1 +Regulation of cell population proliferation 0.3506931030469059 1.7332849597742428 0.0830450326679645 1.0 0.2871073620119222 230 Q08722,P05556,Q13277,P30825,Q969Z0,Q04656,P05067,Q13641,Q15392,P98164,Q06481,Q9H2J4,P08069,P07384,P02786,P21359,Q16539,Q9C0B1,Q99538,Q96DY7,P04083,P31751,Q9UPY3,Q9NWU2,Q32P28,P56545,O95251,P15291,Q9UHI8,Q86X55,P55209,P04439,Q96G23,P06756,P09493,P10644,P19022,P31749,O00560,P40763,O60884 41 +3 phosphoadenosine 5 phosphosulfate biosynthetic process 0.7128946591914884 1.7314705097157277 0.0833678802458215 1.0 0.2879832461500545 2 O43252 1 +Positive regulation of lipid catabolic process 0.7159728373191787 1.7305380458442052 0.0835341898641812 1.0 0.2881443572445937 4 P50416,P31751,Q8NCG7 3 +Regulation of plasma membrane organization 0.7159728373191656 1.730538045844143 0.0835341898641923 1.0 0.2881443572445937 4 P50570,Q9Y371,P35579 3 +Blood vessel morphogenesis 0.5356130358114016 1.730296625969146 0.0835772920715884 1.0 0.2881443572445937 82 P98164,Q9H2J4,Q9NZ08,Q08431,Q07954,P21359,Q16539,Q9Y6I3,O94813,P04083,P04114,P43121,P15291,Q13685,Q9UHI8,Q5JRA6,P42785,P06756,P19022,P31749,P40763 21 +Regulation of short term neuronal synaptic plasticity 0.7125995868987895 1.730110404925822 0.0836105515875633 1.0 0.2881443572445937 2 Q15042 1 +Tissue remodeling 0.7258404686476114 1.7278224588561573 0.0840200595720421 1.0 0.2890965051871006 17 P21359,Q04656,O14773,P38571,P07384,P02786 6 +Integrin activation 0.712009442313353 1.7273897583588416 0.0840976887239959 1.0 0.2892107520302237 2 Q96AC1 1 +Response to growth hormone 0.7150079886854798 1.7260590682238184 0.084336786644914 1.0 0.2894732229619879 4 P31749 1 +Cellular lipid metabolic process 0.3503467584784051 1.7240471081798006 0.0846993392474582 1.0 0.2900421624131347 229 P07602,P17900,P04062,P16278,P98164,Q06481,Q99805,Q07954,P04066,Q8NHP8,P06280,O60512,P06865,Q8TBX8,Q9HBU6,Q9HB40,Q8WTV0,P19021,P50897,P04083,P04114,P31751,Q13510,P07686,Q9NX62,P61916,Q9NWW5,Q11206,P48449,Q8NCC3,Q99519,Q9BV79,P31749,P17655 34 +Histone lysine demethylation 0.7160607668752379 1.7239210690322295 0.0847220932401624 1.0 0.2900421624131347 5 Q8NB78,Q7LBC6 2 +Regulation of sodium proton antiporter activity 0.7108291531425222 1.7219467228916927 0.0850791700515505 1.0 0.290603973208815 2 O43707 1 +Cellular response to ph 0.7108291531425048 1.721946722891613 0.0850791700515649 1.0 0.290603973208815 2 P29992 1 +Vitamin transport 0.718843238380305 1.719745254952041 0.0854787577440516 1.0 0.290603973208815 8 P98164,P04062 2 +Carbohydrate catabolic process 0.6772742613811172 1.7191525412444215 0.0855865998219529 1.0 0.2906461997083535 50 O00462,Q01459,Q99519,P08236,P17900,P05067,Q14108,P16278,P07686,P10253 10 +Vacuole organization 0.6502993645281175 1.718153094541519 0.08576869450771 1.0 0.2909610220141702 58 Q9NQ11,Q14108,P04062,P11117,Q8TBX8,O75503,P07686,P54802,O14773,Q9NWW5,P50897,Q96GC9,Q9NUM4,Q9UN37,Q6UWE0,P10253 16 +Long term synaptic potentiation 0.7215362587655669 1.7165964275776886 0.0860529356760513 1.0 0.2916213489073889 12 P21359,Q13277,Q99538,P05067,Q92542 5 +Positive regulation of protein localization 0.3739424818168885 1.715462558753993 0.0862604542695066 1.0 0.2920205706159586 140 Q96AC1,P05556,Q13277,P23634,O00410,P02786,Q07954,Q9Y6B6,P15311,O95071,Q96HY6,Q9Y5K6,Q16539,O43464,Q92544,P19784,Q96D46,P55786,P53350,P31751,P62258,Q9NV96,Q9Y282,O14777,O95251,P06493,O00264,P27105,Q9NQ11,P31749,O95486,Q05D32 32 +Neutrophil chemotaxis 0.7210984575923294 1.7144972482414047 0.0864374420179432 1.0 0.2921639395310542 12 O94813,P78310 2 +Regulation of secondary metabolic process 0.7107438016528763 1.713696228327289 0.0865845299659149 1.0 0.2925092320073202 3 Q9Y4G8,Q04656 2 +Negative regulation of cell adhesion mediated by integrin 0.7087636470935377 1.7124158547449573 0.0868200592971109 1.0 0.2931527935810123 2 Q9H4A3 1 +Regulation of dendrite extension 0.7072882856299738 1.7056037954546193 0.0880818722476961 1.0 0.296031485974446 2 Q9Y263 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.7104760895884881 1.7050005359739957 0.0881943244607317 1.0 0.2961036886226733 4 Q9BY67 1 +Positive regulation of natural killer cell mediated immunity 0.7104760895884881 1.7050005359739957 0.0881943244607317 1.0 0.2961036886226733 4 Q9BY67 1 +Response to manganese ion 0.7138761630652755 1.701484481689122 0.0888520493896214 1.0 0.2978511027427577 7 P05067,Q9NQ11,P02786 3 +Heart trabecula morphogenesis 0.7073479983537612 1.6979600128650367 0.0895153091983758 1.0 0.2991502376188021 3 Q9UHI8 1 +T cell mediated immunity 0.7159679023698213 1.6933059524172918 0.09039724570541 1.0 0.3008619987434661 11 O15400,Q9BY67,P01889,P53634 4 +Negative regulation of cellular response to insulin stimulus 0.7140990422703051 1.692602659959145 0.0905311244319206 1.0 0.3011536126989288 9 Q06481 1 +Detection of mechanical stimulus 0.7058978449443309 1.691234259485116 0.0907920701881066 1.0 0.3018674039451349 3 P19022 1 +Regulation of cell development 0.4740117372408713 1.6885797377597551 0.091299996375475 1.0 0.3031819832733658 91 Q96AC1,Q15375,Q7L576,Q96N67,Q9UBS4,Q9UJU6,Q16706,P98164,Q06481,Q9Y624,P21359,Q14444,Q07021,O94813,Q9UPY3,A0MZ66,P55209,P61160,Q96G23,P39880,P26583,P31749,Q04917,Q9UQB8,Q8N5W9 25 +Renal system process 0.7140764536748421 1.6881629166332972 0.0913799596105864 1.0 0.3031819832733658 10 Q99538,P43121,Q9UNF1,P61586 4 +Positive regulation of lipid storage 0.7083349826699491 1.6878676772962784 0.0914366325689413 1.0 0.3031819832733658 5 P04114,Q8WTV0 2 +Response to inorganic substance 0.3717249252033171 1.6877101415943143 0.0914668840474486 1.0 0.3031819832733658 108 O15118,Q04656,P05067,P02786,Q99538,Q9NQX3,P19021,P04083,P04114,Q8TAD4,Q14168,Q99720,P00374,Q9NQ11,O60888,P35670,P46934,P31749,O95831,P17655,Q92542 21 +Negative regulation of sister chromatid cohesion 0.7048406139315204 1.686328730664297 0.0917325001848641 1.0 0.3037615805750252 3 P41227,Q7Z5K2 2 +Sodium ion export across plasma membrane 0.7046095612082809 1.6852564126603606 0.0919391113053431 1.0 0.3042476201566203 3 P54709 1 +Positive regulation of stress activated protein kinase signaling cascade 0.713154680402789 1.679845789136324 0.0929873235798321 1.0 0.3069713369699328 11 O43567,P05067 2 +Inflammatory cell apoptotic process 0.7044731199483737 1.6770546557783894 0.0935317945772804 1.0 0.3083271213941904 4 P04083 1 +Lipid metabolic process 0.3414159179036095 1.6741843316580487 0.0940943778482126 1.0 0.3098403640828852 303 P07602,O15118,P17900,P05067,P04062,Q15392,P16278,P98164,Q06481,O14773,P38571,Q99805,Q07954,P04066,Q8NHP8,P06280,Q99538,O60512,P06865,Q8TBX8,Q9HBU6,Q9HB40,Q8WTV0,P19021,P50897,Q9UBM7,P04083,P04114,P31751,Q8N4Q0,Q13510,P07686,Q9NX62,P15291,P61916,Q9NWW5,Q11206,Q86UY6,P48449,Q8NCC3,Q99519,Q9BV79,Q16739,P31749,P17655 45 +Monovalent inorganic cation homeostasis 0.7094153503191283 1.6739191911419522 0.094146481963693 1.0 0.3098552060584639 30 P61421,P51790,Q9Y487,Q93063,Q92544,O75503,Q9NUM4,Q9NWW5,P50897,Q15904,Q93050 11 +Negative regulation of protein metabolic process 0.3401227616644526 1.672921643186517 0.0943427224737201 1.0 0.3103441754946528 283 P07858,Q10713,O95816,Q9C0C9,P04062,P05067,Q15392,Q96ST3,Q06481,Q9H2J4,P60866,P23634,Q9Y287,O00410,Q07954,P21359,O95071,Q96HY6,Q9C0B1,Q9H074,Q99471,P19784,Q14444,O43293,Q9Y6M1,Q92896,Q14671,P11413,Q8IXB1,O94813,Q5PRF9,P53350,O60573,P10619,Q96KB5,P62258,Q9BX68,Q32P28,P62942,P67809,Q96PZ0,Q7Z739,P00374,P34896,P29375,Q9NQ11,Q01105,P06756,Q9GZU8,P10644,Q15041,P31749,P46379,P31946,O00560,P40763,P26368,Q9BRG1 58 +Granulocyte chemotaxis 0.7134147155281856 1.6697720467967614 0.0949644729469854 1.0 0.3117593136081064 15 O94813,Q07021,P78310 3 +Localization within membrane 0.3563950598592347 1.6675820339111505 0.0953987271909211 1.0 0.3127118398856478 193 Q96AC1,P05556,Q13277,Q15629,P07602,P56589,P54709,Q15334,Q14254,O15118,Q8TAG9,Q13641,Q9H223,P23634,Q9ULT8,Q9H173,O43752,Q9Y624,Q99805,Q07954,O15027,P15311,Q9NQX3,Q9H3S7,Q13464,Q92544,P42566,P05026,Q9H2M9,Q15070,Q15904,Q9HD45,P31751,P40855,O00264,P27105,Q14168,O15400,Q13136,Q8N3R9,P41440,Q9H4M9,P19022,Q15041,O75955,P31749,P11233,Q9P0I2,P46379,O00560,Q9UN37,O75915,Q4J6C6 53 +Regulation of fat cell differentiation 0.7120266957362064 1.6652014873496692 0.0958725643445639 1.0 0.3137910477039272 14 Q99523,Q16539,Q8N4Q0,Q9C0B1,P31749,Q86X55 6 +Response to interleukin 1 0.7114790568321117 1.6603324309027307 0.0968475949490437 1.0 0.3163461330247238 15 Q08722,P05067 2 +Nonribosomal peptide biosynthetic process 0.7004067746545573 1.6580918388594992 0.0972989309045897 1.0 0.3176156343594063 4 Q8WUX2 1 +Endochondral bone morphogenesis 0.7033858300422846 1.6578615502951908 0.0973454144524859 1.0 0.3176156343594063 6 Q9NX62 1 +Postsynaptic actin cytoskeleton organization 0.7018814088042831 1.657677328129483 0.0973826123166474 1.0 0.3176156343594063 5 Q9UJU6 1 +Positive regulation of cellular carbohydrate metabolic process 0.7030958344744409 1.656498485207655 0.0976209115685753 1.0 0.3180741412970096 6 P31749 1 +Positive regulation of glucose metabolic process 0.7030958344744409 1.656498485207655 0.0976209115685753 1.0 0.3180741412970096 6 P31749 1 +Cartilage development 0.7085762414920063 1.6511610160243126 0.0987057009937024 1.0 0.3204290080823495 13 Q16539,Q04656,Q9NX62,Q8N5W9,Q92896,O75844 6 +Negative regulation of cellular amine metabolic process 0.695485393921496 1.650981834476936 0.0987422842166914 1.0 0.3204290080823495 2 P23634 1 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.7070209798717411 1.6504538376218547 0.0988501474760281 1.0 0.3204290080823495 11 P05067 1 +Viral life cycle 0.4058948016048171 1.641606555328937 0.1006715682560857 1.0 0.3225553363319364 100 P05556,P07858,P08195,P11279,P06756,O15118,Q14108,Q9UNP9,Q8WTV0,P46934,Q9Y3E7,P56545,P27105,P78310,Q9UN37,Q6UWE0,Q9Y624,P02786 18 +Innate immune response 0.370155513322378 1.6390183585327769 0.1012094363414333 1.0 0.3234770384447026 124 Q08722,P04083,Q9BY67,P10321,Q9NUD5,Q5KU26,Q7Z739,P11279,Q06481,P01889,O43293,O00584,P61160,Q9NZ08,Q07021,P04439 16 +Sphingolipid metabolic process 0.6963955653637521 1.637673566472854 0.1014898076160575 1.0 0.3241897191268569 35 Q8NCC3,Q99519,P07602,O60512,P06280,P06865,P17900,P04062,Q13510,P16278,P07686,Q9NWW5,P50897,Q99805 14 +Cell differentiation in spinal cord 0.6941533781446338 1.6366416455181787 0.1017053685352524 1.0 0.3242418947916227 3 Q8NCM8 1 +Spinal cord motor neuron differentiation 0.6941533781446338 1.6366416455181787 0.1017053685352524 1.0 0.3242418947916227 3 Q8NCM8 1 +Engulfment of apoptotic cell 0.6922395987016827 1.6359228971683268 0.1018557251860599 1.0 0.3242850247598732 2 P63000 1 +Regulation of tube size 0.7042486008638518 1.6334633732039203 0.1023715779303793 1.0 0.3254096544564304 12 P42892,Q9HB40 2 +Positive regulation of organ growth 0.6978801478000697 1.6319611173331037 0.1026876775251599 1.0 0.3262551394283998 6 Q16539,P31749,P06493 3 +Membrane lipid metabolic process 0.6781584926094448 1.6304367153791146 0.103009230179254 1.0 0.3269576248010451 44 Q8NCC3,Q99519,P04066,P07602,O60512,P06280,P06865,P17900,P04062,Q13510,P16278,P07686,Q9NWW5,P50897,Q11206,Q99805 16 +Regulation of neural precursor cell proliferation 0.7052247824050769 1.6297908000134331 0.1031457188655582 1.0 0.3272313010793294 15 P21359,P98164,Q06481,P55209 4 +Positive regulation of dendritic spine morphogenesis 0.6995128857833744 1.628299736426455 0.1034613453548789 1.0 0.3277534590074267 8 Q14444,P61160,Q9UQB8 3 +Immune effector process 0.572155364771305 1.6274090800282752 0.1036502443456119 1.0 0.3281921647324581 73 Q08722,P04083,Q9BY67,P04439,O15400,P11279,P05067,Q06481,P01889,P40763,P53634,Q07021,P02786,Q07954 14 +Positive regulation of connective tissue replacement 0.6918536009445058 1.6259267359472904 0.1039652417847065 1.0 0.3282202574756722 3 Q13464,O75116 2 +Connective tissue replacement 0.6918536009445058 1.6259267359472904 0.1039652417847065 1.0 0.3282202574756722 3 Q13464,O75116 2 +Positive regulation of tissue remodeling 0.6918536009445058 1.6259267359472904 0.1039652417847065 1.0 0.3282202574756722 3 Q13464,O75116 2 +Regulation of connective tissue replacement 0.6918536009445058 1.6259267359472904 0.1039652417847065 1.0 0.3282202574756722 3 Q13464,O75116 2 +Negative regulation of dendrite morphogenesis 0.6918536009444989 1.6259267359472591 0.1039652417847132 1.0 0.3282202574756722 3 Q9Y4G8,Q04917 2 +Glycoprotein biosynthetic process 0.6247414166516457 1.6242409610568609 0.1043243919888847 1.0 0.3282546544129252 61 O15118,Q04656,Q16706,Q9NRB3,Q9Y287,Q99805,O60512,Q86SF2,Q10472,Q8NCH0,Q7LGA3,Q9P2E5,P15291,O43505,Q11206,Q8WVQ1,Q93063,Q10471,Q92542 19 +Forebrain neuron development 0.6926026737853539 1.6216273955591658 0.1048831531371958 1.0 0.3282546544129252 4 Q04656 1 +Forebrain neuron differentiation 0.6926026737853539 1.6216273955591658 0.1048831531371958 1.0 0.3282546544129252 4 Q04656 1 +Cellular response to hormone stimulus 0.3679126778432945 1.6083624116773032 0.1077558289695401 1.0 0.3338840773877708 129 P04083,P07858,P04114,P31751,Q16739,Q9P1Z2,O15118,Q8TBX8,P31749,Q06481,Q9UQB8,P40763,P42785,Q86X55,Q92572,O94813 16 +Synaptic transmission glutamatergic 0.6930924568693875 1.6033957871322402 0.1088473005642001 1.0 0.3367851362513986 7 P21359,P51790 2 +Positive regulation of leukocyte chemotaxis 0.6971350499957483 1.6029579301388246 0.1089439425225031 1.0 0.3369240217679314 11 Q99538 1 +Stem cell proliferation 0.6952673173393966 1.5982723274718684 0.1099823831859501 1.0 0.3396514774860223 10 P26583,P04062,P08183,O95251 4 +Histone h3 k4 demethylation 0.6851611429744102 1.594701929663071 0.1107789063360842 1.0 0.3411403407038355 3 Q8NB78 1 +Adult locomotory behavior 0.6982746746834927 1.5937131407730556 0.1110002996295411 1.0 0.3414729678326497 16 P51790,O15118,O43464,P05067,P50897,Q14671 6 +Regulation of protein localization to cilium 0.6843895896963801 1.591098013370154 0.1115875195606692 1.0 0.3422266556280424 3 Q10713 1 +Import across plasma membrane 0.6984591843891917 1.5909328330035748 0.111624692520784 1.0 0.3422266556280424 20 P41440,P05556,P31751,P08195,P30825,P54709,Q15041,P31749,P98164,O75915 10 +Dna dealkylation involved in dna repair 0.6843304006036235 1.5908215074663694 0.1116497512500247 1.0 0.3422266556280424 3 Q9C0B1 1 +Oocyte construction 0.683197155549006 1.5855265366069728 0.1128467525818082 1.0 0.3453842780007388 3 Q9Y2W6 1 +Regulation of synapse structure or activity 0.6837752773408073 1.5850586582462418 0.1129530074580291 1.0 0.3455470293946286 37 Q15375,Q16539,Q9UQ16,P46934,P19022,Q7L576,P05067,Q13641,Q9UJU6,Q14444,O00264,P50897,Q9UQB8,P61160,Q14203 15 +Layer formation in cerebral cortex 0.6843508769990978 1.5829738791514163 0.1134274181236618 1.0 0.3463473226946711 4 Q96N66 1 +Purine ribonucleoside salvage 0.6857959105068071 1.5821526347464856 0.1136147302247505 1.0 0.3464318003574361 5 Q13126 1 +Nucleoside salvage 0.6857959105068071 1.5821526347464856 0.1136147302247505 1.0 0.3464318003574361 5 Q13126 1 +Protein localization to lysosome 0.6955523314946697 1.5786272709152618 0.1144215756809474 1.0 0.3479142726216571 17 Q99523,Q9NQ11,P13473,Q14108,P20645,Q9UN37 6 +Modification of postsynaptic actin cytoskeleton 0.6844994555571307 1.5760493331816043 0.1150144343450247 1.0 0.3489021284185048 5 Q7L576,Q9UQB8,P61586 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.6856177142757527 1.5679614609907933 0.1168901267093422 1.0 0.3529612285896035 7 P04062,O43464 2 +Response to mitochondrial depolarisation 0.6856177142757527 1.5679614609907933 0.1168901267093422 1.0 0.3529612285896035 7 P04062,O43464 2 +Synapse organization 0.5740172415713722 1.5679419242852797 0.1168946864576321 1.0 0.3529612285896035 71 Q15375,Q15334,Q9UQ16,Q7L576,P05067,Q13641,Q9UJU6,P08069,P10586,Q16539,Q99538,Q9NQX3,P61586,Q14444,P12814,P56545,O00264,Q16352,Q13136,P61160,Q14203,P46934,P19022,P43034,O00560,Q9UQB8,Q9BRK5 27 +Regulation of blood pressure 0.6936652664653116 1.5675859590870076 0.1169777910310148 1.0 0.3529856844576812 22 Q6P179,Q9UIQ6,P09493,Q93063,Q9HB40,P42892,P42785 7 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.67932965409142 1.567442784774504 0.1170112299630838 1.0 0.3529856844576812 3 P08069 1 +Regulation of rho protein signal transduction 0.691217053761643 1.566948880045483 0.1171266409914513 1.0 0.353006681877013 13 P41440,Q9H3F6,P05556,O75955,Q9Y624 5 +Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.6768958394806535 1.56452827586184 0.1176935579328348 1.0 0.354387170278795 2 P16989 1 +Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.6768958394806535 1.56452827586184 0.1176935579328348 1.0 0.354387170278795 2 P16989 1 +Circulatory system process 0.5383425913812522 1.5631927181973324 0.1180072723703786 1.0 0.3551675187846348 78 Q96AC1,P30825,Q9UIQ6,P98164,P42892,O75787,P08183,P23634,Q9NZ08,P02786,Q07954,Q9HB40,P61586,P78310,Q14126,P10253,O94813,P62258,P42785,P41440,Q6P179,Q9UDY2,P09493,Q93063,P29992,O75844 26 +Maintenance of dna repeat elements 0.6796575140242058 1.5609466920858104 0.1185363291866261 1.0 0.356594964420026 4 O75844,P52701,P20585 3 +Positive regulation by host of viral process 0.6863404526844956 1.5603360371859385 0.118680491511788 1.0 0.3568637412202033 9 P11717 1 +Phosphatidylinositol 3 kinase signaling 0.6889652655147828 1.5595825507847236 0.1188585626551468 1.0 0.3572341841574357 12 P21359,P46934,P31749,Q8NDZ4,P08069,Q07021 6 +Regulation of leukocyte chemotaxis 0.6905368391736271 1.5578289822534697 0.1192737937202212 1.0 0.3576847518831381 15 Q99538,O94813 2 +Learning 0.6912357632721723 1.5550456022339678 0.1199352089895811 1.0 0.3589784875964014 19 P21359,P05556,Q99538,P05067,Q13641,P50897,P61160 7 +Regulation of nervous system process 0.6875843299395753 1.5528906147813475 0.1204492693339509 1.0 0.359893689122595 12 P53634,P05067,Q9UQB8 3 +Positive regulation of erk1 and erk2 cascade 0.6894646432637479 1.5484677459855756 0.1215097214760621 1.0 0.3618644872732421 17 P05067,Q13641 2 +Negative regulation of receptor mediated endocytosis 0.6834998247492633 1.5467379928525224 0.1219264377034194 1.0 0.3629360354134709 9 O00560,P05067 2 +Acylglycerol homeostasis 0.6761835623283537 1.544623694447722 0.1224373114987504 1.0 0.3641237541602858 4 Q8WTV0 1 +Endocrine pancreas development 0.6777679512106163 1.5443232217481864 0.1225100496789159 1.0 0.3641737093195174 5 P04083,P31749 2 +Positive regulation of small gtpase mediated signal transduction 0.6790603847299352 1.5430943573793896 0.1228078836137065 1.0 0.3646428932201755 6 P06756,Q9Y624 2 +Radial glial cell differentiation 0.6755902315117752 1.5418342633315287 0.1231138735772576 1.0 0.3653014206873051 4 P19022,P40763 2 +L serine transport 0.6718796105045757 1.541118096424741 0.1232880463093599 1.0 0.3656515633138649 2 Q9H9B4 1 +Positive regulation of reproductive process 0.6811241141679566 1.540786306230958 0.1233688033083373 1.0 0.3657244578949344 8 P36896 1 +Positive regulation of dendrite morphogenesis 0.6841246331201698 1.540234006393295 0.1235033234549727 1.0 0.3659565933963916 11 P39880,Q9UJU6,P43034,Q14444,Q9UQB8,P61160 6 +Cellular transition metal ion homeostasis 0.6876163479143281 1.5377753833709784 0.1241035444976261 1.0 0.3667335790647055 23 P61421,Q9NQ11,Q9Y487,P35670,Q04656,P05067,Q15904,P02786 8 +Long chain fatty acid import across plasma membrane 0.6743290085169062 1.5359033819042294 0.1245620785888539 1.0 0.3675143831252662 4 P31749 1 +Negative regulation of rho protein signal transduction 0.6787935266070346 1.535544888748329 0.1246500396222101 1.0 0.3675143831252662 7 Q9H3F6 1 +Lymphocyte activation 0.382002128734194 1.5319524414720889 0.1255341711445508 1.0 0.3687849522342173 102 Q08722,P05556,P04062,Q04656,P02786,P78310,P04083,Q9BY67,P11279,P62942,O95251,O96028,P04439,P10644,P31749,P46379,O60934,P40763,Q92542 19 +Receptor mediated endocytosis 0.6250136164344292 1.5301802640823947 0.1259721151094417 1.0 0.369636389757826 57 P05556,Q9UQ16,P06756,P46934,Q5VW38,Q14108,P05067,O75955,P98164,O00560,P20645,P50897,P11717,P02786,Q07954 15 +Diterpenoid biosynthetic process 0.6695190321628823 1.5300904600363563 0.1259943393045488 1.0 0.369636389757826 2 O60678 1 +Response to vitamin a 0.6695190321628821 1.5300904600363547 0.1259943393045492 1.0 0.369636389757826 2 P46821 1 +Regulation of glycolytic process 0.6786690751331012 1.529067943560228 0.1262476012827109 1.0 0.3702125605182199 8 P05067 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.6758373778368344 1.5278274716599434 0.1265553795728398 1.0 0.3709480058618581 6 P46934,Q8NDZ4,P08069 3 +Positive regulation of sodium ion transmembrane transport 0.6771076303605311 1.521610925050048 0.1281065984724945 1.0 0.37448314147101 8 P54709,P35754,O43707,Q9H4A3,P05026,P50570 6 +Lipid storage 0.6837704463494504 1.5202112344514764 0.128457894758986 1.0 0.3748367973469292 17 P04114,Q9H4M9,P06756,P17900,P04062,Q8WTV0,P07686 7 +Establishment of tissue polarity 0.6788577694924322 1.519428938093563 0.1286545625128825 1.0 0.3750022994693407 10 Q8TAA9,P60953,Q13308,Q93074,P43034,P61586 6 +Peroxisome fission 0.6708001180986254 1.5192983096092032 0.1286874250406309 1.0 0.3750022994693407 4 O14734,P40855,Q9Y3D6 3 +Cytoplasm organization 0.6685198365868478 1.5167943701753737 0.1293186088933078 1.0 0.3763362288312176 3 Q9Y2W6 1 +Organic hydroxy compound metabolic process 0.3613628654579478 1.5158301539787964 0.1295623051985426 1.0 0.3768769467571548 124 P07858,O15118,P04062,P05067,Q04656,Q15392,P98164,P38571,Q99538,Q8WTV0,P61457,Q9UBM7,P04114,Q13510,Q9NX62,P61916,Q9NWW5,P48449,P00374,Q13572 20 +Leukocyte mediated cytotoxicity 0.6823899874237439 1.515347153910506 0.1296845127659243 1.0 0.377063947345318 16 Q9BY67,P11279,P01889,O15400,P53634 5 +Regulation of synapse structural plasticity 0.6662732369430487 1.5149162969045948 0.1297936027241784 1.0 0.3772126579171434 2 P60953 1 +Establishment of endothelial intestinal barrier 0.6764147534564424 1.5127764387904648 0.1303364555722024 1.0 0.3784524200602309 9 Q9Y624 1 +Camera type eye morphogenesis 0.6775436601761201 1.5084208013057805 0.1314468624944642 1.0 0.380802942978791 11 P21359,P54802,Q16706 3 +Regulation of histone h4 acetylation 0.6716548838935784 1.507996490193868 0.1315554253086484 1.0 0.380802942978791 6 O95251 1 +Response to cytokine 0.3559853975437289 1.505887548056566 0.1320960436182945 1.0 0.381347555354556 162 Q08722,O15111,P04062,P05067,Q06481,P02786,Q16539,O43464,P61586,P33993,P16989,O43293,P19623,O94813,Q8TCT8,P04083,P51858,P04114,Q13510,P56545,P52789,P67809,Q16352,P60604,Q8NFH5,P61160,P63241,P34896,Q7Z739,Q16739,Q99829,P43034,P31749,P40763,P17655 35 +Cell projection assembly 0.357907566424766 1.5055771994091476 0.1321757452450356 1.0 0.381347555354556 107 Q9NR77,P05556,Q9UQ16,P10155,Q7L576,Q04656,Q9UJU6,Q9H223,Q9Y4G8,Q9P258,P15311,Q9Y5K6,Q9H3S7,Q13464,Q9P2S5,Q96C92,O94813,Q5T0N5,Q15555,P60953,P61421,A0MZ66,A6NIH7,Q7Z3E5,Q9ULC3,Q16181,P61160,Q14203,Q9Y496,Q8NCM8,Q9H4M9,O15078,P11233,O00560,Q9BW27,Q9Y3P9,Q15154 37 +Regulation of fatty acid metabolic process 0.6784985458143532 1.5049794542083288 0.1323293590700371 1.0 0.381347555354556 13 P04083,Q06481,P31749 3 +Negative regulation of wnt signaling pathway 0.6808808799567576 1.5031483748470875 0.1328007866904283 1.0 0.3823237659174673 19 Q16539,Q13641,Q07954 3 +Negative regulation of small gtpase mediated signal transduction 0.6780888120801669 1.5029796385483418 0.1328442947012766 1.0 0.3823237659174673 13 P21359,Q9H3F6,P05556,Q9Y5K6,O94813 5 +Neuron cellular homeostasis 0.6702539207395509 1.5013492491607874 0.1332652530655895 1.0 0.3832307019896355 6 P51790,Q14203 2 +Negative regulation of blood pressure 0.6686114668753094 1.5010755278058103 0.1333360276507718 1.0 0.3832307019896355 5 Q9HB40 1 +Synapse assembly 0.6804448409539533 1.5002818125490318 0.1335414185980534 1.0 0.3834824151183626 20 Q15375,Q9UQ16,P19022,P05067,Q13641,O00560 6 +Negative regulation of endocytosis 0.676314256592633 1.4981835122707772 0.1340855781472942 1.0 0.3847452265781114 12 Q6UWE0,O00560,P05067 3 +Regulation of systemic arterial blood pressure 0.6732416814056421 1.4975465957885576 0.1342510907504961 1.0 0.3850108373505417 9 P42785,P42892,P09493 3 +Positive regulation of aspartic type peptidase activity 0.6624372971378014 1.4969671076460025 0.134401816932397 1.0 0.3851736966614675 2 O75116 1 +Positive regulation of ubiquitin protein ligase activity 0.6658585295787962 1.4960207029593866 0.1346482602341878 1.0 0.3854706130714876 4 P53350 1 +Regulation of protein localization to endosome 0.6651560419331364 1.4927093027453346 0.1355132971940627 1.0 0.3873024188962801 4 P15311,O75116 2 +Positive regulation of protein localization to early endosome 0.6651560419331364 1.4927093027453346 0.1355132971940627 1.0 0.3873024188962801 4 P15311,O75116 2 +Locomotory behavior 0.6730487396602503 1.4907663059435836 0.136022860861245 1.0 0.3879539392321539 32 Q9HB07,P51790,O15118,Q04656,P05067,P07686,P54802,Q9NWW5,P50897,P10253 10 +Response to retinoic acid 0.6717223848777925 1.4902502129112003 0.1361584579993344 1.0 0.3880873737196442 9 P11717 1 +Regulation of aspartic type peptidase activity 0.6626328217237274 1.4891514583705463 0.1364474898813394 1.0 0.3884478303235173 3 O75116,P49755 2 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.6626328217237274 1.4891514583705463 0.1364474898813394 1.0 0.3884478303235173 3 O75116,P49755 2 +Heart development 0.4788785323412111 1.4890890131562806 0.1364639305606581 1.0 0.3884478303235173 87 P05556,P98164,P42892,P08069,P21359,Q16539,Q93074,P19021,P78310,Q14126,P11413,P10253,O94813,P62942,P06493,Q8NDZ4,Q9UHI8,O96028,P09493,P10644,P29992,O75844 22 +Positive regulation of filopodium assembly 0.6689837868833144 1.4888439065167498 0.1365284774205761 1.0 0.388461708045433 7 Q5T0N5,P11233,Q9UQ16 3 +Regulation of protein tyrosine kinase activity 0.6723014367599135 1.4878309174890032 0.1367954898597743 1.0 0.3888815017411051 10 P05067 1 +Regulation of membrane repolarization 0.6639160436045967 1.4868628188605582 0.1370510460511407 1.0 0.3890982598311931 4 P62258 1 +Multi multicellular organism process 0.6712087157370865 1.486533098526459 0.1371381688030215 1.0 0.389175884441007 33 P07858,Q9UIQ6,Q04656,P07686,P31749,P15291,Q9GZP4,Q96GC9,P19021,P17655,P36896,Q07021,Q9Y6I3 13 +Vesicle fusion to plasma membrane 0.6649528414806849 1.4837674552167812 0.1378706238046487 1.0 0.3906966793624098 5 Q13277 1 +Regulation of ventricular cardiac muscle cell action potential 0.6632381377473088 1.483665828777887 0.1378975959542563 1.0 0.3906966793624098 4 Q14126,P15924 2 +Negative regulation of protein localization to cell surface 0.6591915019179724 1.4817662739672148 0.138402495863728 1.0 0.3910591354482939 2 Q13492 1 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.6705102877507528 1.4791898075884984 0.1390895928671718 1.0 0.3916406788777199 10 Q14126,Q9BY67,Q14574,P19022 4 +Cellular response to oxygen containing compound 0.3425677481691155 1.4785408945339455 0.1392630596355464 1.0 0.3919595841882434 203 O15111,Q7L576,P05067,P23396,O15164,Q04656,Q96ST3,Q06481,P23634,O00410,P08069,P46060,P26358,Q07954,P17480,P15311,Q5KU26,Q13308,Q16539,Q99538,Q8TBX8,Q8WTV0,O43464,P61586,Q99808,Q8N183,O94813,P04083,P31751,Q9Y263,P06493,Q6IAA8,P61160,Q99720,P34896,P00374,Q96RR1,P09493,P26583,P31749,Q92572,O95831,Q9UQB8,P17655,Q92542,P40763,P29992,P50416,Q13185 49 +Axon development 0.5279328851278462 1.477235303210631 0.13961257357802 1.0 0.3927734891931333 78 Q15375,P05556,Q7L576,P05067,Q96N67,Q9UJU6,P42892,Q06481,P08069,Q92859,P10586,O94813,A0MZ66,O00264,P00374,Q96G23,P41440,P19022,O75955,Q9UQB8 20 +Regulation of neuronal synaptic plasticity 0.6696623513725427 1.475097820601398 0.1401862463082435 1.0 0.3940525347957858 10 P21359,P05067 2 +Trabecula morphogenesis 0.6613725445693429 1.4748651350379294 0.1402488053950592 1.0 0.3940525347957858 4 P62942,Q9UHI8 2 +Regulation of anion channel activity 0.6593860684769612 1.473889402557312 0.1405113715265149 1.0 0.3944267146939092 3 Q9Y4C2,P08183 2 +Response to muramyl dipeptide 0.662783533188852 1.4734979560851948 0.1406168145669015 1.0 0.3944267146939092 5 Q16539 1 +Regulation of histamine secretion by mast cell 0.6574210681617028 1.47347005502057 0.1406243325352631 1.0 0.3944267146939092 2 Q9UNH7 1 +Negative regulation of hormone metabolic process 0.657125995868991 1.4720870267027508 0.1409973783472415 1.0 0.3949440609282063 2 O60678 1 +Negative regulation of protein dephosphorylation 0.6666867658960017 1.4717694207347345 0.1410831538821193 1.0 0.3949440609282063 8 P62258,P62942,Q15257,Q13464,P31946 5 +Regulation of stem cell proliferation 0.6640028666555478 1.471662208564638 0.1411121176219674 1.0 0.3949440609282063 6 P26583,O95251 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.6728142961933874 1.470605719106754 0.1413977763930485 1.0 0.3955734956247296 15 Q96DY7,P31749,Q9UHI8 3 +Protein localization to presynapse 0.6582348867700862 1.4684753065315528 0.1419751590004203 1.0 0.3966773755762817 3 Q14168 1 +Axo dendritic protein transport 0.6582348867700862 1.4684753065315528 0.1419751590004203 1.0 0.3966773755762817 3 Q14168 1 +Cellular potassium ion homeostasis 0.6595209667943434 1.4661268699184082 0.1426137267551384 1.0 0.3972680193307449 4 P54709 1 +Cellular sodium ion homeostasis 0.6595209667943434 1.4661268699184082 0.1426137267551384 1.0 0.3972680193307449 4 P54709 1 +Potassium ion homeostasis 0.6595209667943434 1.4661268699184082 0.1426137267551384 1.0 0.3972680193307449 4 P54709 1 +Positive regulation of sodium ion transmembrane transporter activity 0.6639539567419213 1.4648555076205168 0.1429603438828834 1.0 0.3979701352365011 7 P35754,O43707,Q9H4A3,P05026,P50570 5 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.6573266238608046 1.4642026961379135 0.143138573787493 1.0 0.3979701352365011 3 P19022 1 +Interleukin 8 production 0.6645899192033186 1.4617257716830314 0.1438163720490797 1.0 0.3994217500168553 8 P04083 1 +Glycosylceramide biosynthetic process 0.6565469229384064 1.4605341813904864 0.1441433204570195 1.0 0.3998180725075402 3 O60512 1 +Oligodendrocyte development 0.6654616097047795 1.460155697573989 0.1442472879515817 1.0 0.3999360496442917 9 Q93074,Q92542 2 +Respiratory gaseous exchange by respiratory system 0.6674877421528858 1.4597092391011346 0.1443700016075078 1.0 0.4001058792953919 11 Q7KZN9,Q16706,P10253,Q9C0B1 4 +Regulation of nervous system development 0.5594036092267699 1.4573749929230913 0.1450128961056458 1.0 0.4010803618587341 71 Q15375,Q7L576,Q96N67,Q9UJU6,Q13641,Q16706,P98164,Q06481,P21359,Q14444,P53634,O94813,Q9UPY3,A0MZ66,P55209,P61160,P39880,Q96G23,P26583,P31749,Q04917,Q9UQB8 22 +Anterograde dendritic transport of neurotransmitter receptor complex 0.6538802006491624 1.456867738884798 0.1451528928631609 1.0 0.4010803618587341 2 P33176 1 +Regulation of binding 0.3831377207102281 1.4553430628328152 0.1455743105736406 1.0 0.4016835190543592 101 O95816,P05067,O75503,Q96ST3,P10586,Q07954,Q96D46,P53350,Q9UBB9,P62942,P40855,P56545,Q00403,Q86X55,P41440,Q99829,Q9GZU8,P26583,O75955,P11234,P31749,O75844 22 +Odontoblast differentiation 0.6529949837710272 1.452715164372486 0.1463028548327865 1.0 0.4034017725376705 2 P46821 1 +Positive regulation of glucose transmembrane transport 0.6604855318694021 1.448298176410615 0.1475336774638254 1.0 0.4058431902327951 7 P31751,P31749 2 +Protein o linked glycosylation via serine 0.6571364233454953 1.446741311832628 0.1479693893637594 1.0 0.4064475631890608 5 Q10472 1 +Lipoprotein biosynthetic process 0.6664096351509385 1.4458947726331013 0.148206718336332 1.0 0.4069277673426915 13 P04062,P04114,Q9H490,Q16739 4 +Negative regulation of cell junction assembly 0.6583898005810636 1.4449693313089436 0.148466500256047 1.0 0.4074691891512926 6 Q15375,Q9P258,Q13464 3 +Regulation of lipid storage 0.6619434748523104 1.4432263361247455 0.1489567229624229 1.0 0.4084702049222296 9 P06756,P04114,Q8WTV0,Q9H4M9 4 +Postsynaptic cytoskeleton organization 0.6579011241474444 1.4426439327397351 0.1491208008223141 1.0 0.4086073989346024 6 Q9UJU6 1 +Natural killer cell mediated immunity 0.6639618056242582 1.44260318487694 0.1491322856941037 1.0 0.4086073989346024 11 P11279,Q9BY67,P01889 3 +Vacuolar transport 0.6176243825190928 1.4407148764569429 0.1496652503544264 1.0 0.4098486974575218 55 Q99523,P61421,P07602,P13473,Q9Y3E7,P11279,O15118,Q14108,Q9NQ11,P46934,Q92572,Q9NUM4,P20645,Q9BRG1,Q9UN37,P11717,Q07954 17 +Relaxation of cardiac muscle 0.6523022432113253 1.4405521581049987 0.1497112446319488 1.0 0.4098486974575218 3 P05023,P05026 2 +Positive regulation of epithelial to mesenchymal transition 0.6557340923776834 1.4400919441763558 0.1498413879506799 1.0 0.4099449434499169 5 O00560 1 +Dna replication synthesis of rna primer 0.6521812922775214 1.4399825187774449 0.1498723449171739 1.0 0.4099449434499169 3 P49643 1 +Lactation 0.6645542012577561 1.4368123239779056 0.150771327661535 1.0 0.4117119727670272 13 P35670,Q04656,Q9UNS2,P00403,P19021,Q99808 6 +Positive regulation of blood pressure 0.6530917259980346 1.4357578404180529 0.1510712602328947 1.0 0.4119749572528108 4 P09493 1 +Brain morphogenesis 0.6578520012522918 1.4357183647345648 0.1510824973415272 1.0 0.4119749572528108 7 P21359,P19022,P04062,P43034 4 +Cerebellar cortex morphogenesis 0.6578238672858414 1.435583938594148 0.1511207677296024 1.0 0.4119749572528108 7 Q04656,P04062 2 +Protein targeting to vacuole 0.6662360137343483 1.4353236371075275 0.1511948951407551 1.0 0.4120045070599899 16 Q99523,P13473,Q14108,P20645,Q9UN37 5 +Cardiac chamber development 0.6674854321517393 1.434808096718746 0.1513417900292908 1.0 0.4122322397868967 20 P09493,P62942,P98164,Q9UHI8,P08069,O94813 6 +Negative regulation of phosphoprotein phosphatase activity 0.6545549132691764 1.4344992244599808 0.1514298502474758 1.0 0.4122995922672804 5 P62942,Q15257,Q13464 3 +Defense response to gram positive bacterium 0.6527098891910796 1.4339529396469533 0.1515856929074854 1.0 0.4125513632222953 4 P04439 1 +Relaxation of muscle 0.6524948331857154 1.4329363335366812 0.1518760327028387 1.0 0.413168814415161 4 P05023,P30626,P05026 3 +Collagen metabolic process 0.6595455821965542 1.4211604726979838 0.1552701129422402 1.0 0.419422587242317 11 Q9UBG0,P05556,P07858,Q32P28 4 +Positive regulation of pattern recognition receptor signaling pathway 0.6563719287048354 1.4163911494194468 0.1566610137923949 1.0 0.4217685030308528 9 Q14671,Q9NUD5,Q9Y4E8,O75955 4 +Morphogenesis of an endothelium 0.6469798512417064 1.415472673909847 0.1569299548756528 1.0 0.4221545480332645 3 P61586 1 +Protein localization to cell periphery 0.4710219764947102 1.4148384135647885 0.1571158784254676 1.0 0.4224801191862015 87 P05556,Q13277,Q15334,P54709,Q14254,Q13641,Q9H223,P23634,Q9ULT8,Q9Y624,Q07954,O15027,P15311,Q13464,Q15904,P53350,P31751,O00264,O15400,Q13136,Q8N3R9,P41440,Q9H4M9,P19022,O75955,P31749,Q9UN37,O75915,Q4J6C6 29 +Regulation of glucose import 0.659654556349768 1.4128121614049984 0.157710961481293 1.0 0.4232062486575506 13 Q06481,P31751,P31749 3 +Regulation of glucan biosynthetic process 0.6515144383034427 1.4122318578714552 0.157881702986582 1.0 0.4233154392267911 6 P31749 1 +Regulation of glycogen metabolic process 0.6515144383034427 1.4122318578714552 0.157881702986582 1.0 0.4233154392267911 6 P31749 1 +Embryonic body morphogenesis 0.6441428149896744 1.411148593981317 0.1582008040711469 1.0 0.4239963913146012 2 Q7Z460 1 +Schwann cell differentiation 0.6573087619646525 1.410292765805259 0.1584532537371601 1.0 0.4243619184415015 11 P21359,Q9UPY3,P31751,Q93074,P31749,P06493 6 +Positive regulation of protein exit from endoplasmic reticulum 0.6493013706527457 1.409566765561172 0.1586676461515666 1.0 0.4243802197220786 5 Q9Y6B6,Q92544 2 +Rna mediated gene silencing by inhibition of translation 0.6492906227182675 1.4095157327613093 0.1586827247126851 1.0 0.4243802197220786 5 Q9BWF3,O60573,P40763 3 +Lysosomal transport 0.6335493507624328 1.4070375841920049 0.1594162443294395 1.0 0.4260261701907437 47 Q99523,Q9NQ11,P07602,P13473,P11279,O15118,Q14108,Q9NUM4,P20645,Q9UN37,P11717,Q07954 12 +Leukocyte migration 0.6308407701825665 1.4047240489819277 0.1601033516233894 1.0 0.4273361291792804 48 Q08722,P04083,P23229,Q99538,P04062,P05067,P31749,Q11206,P15291,Q07021,P78310,Q5JRA6,Q9Y624,O94813 14 +Sarcomere organization 0.6524420334493313 1.4034530394459577 0.1604817861840364 1.0 0.4280884304248279 8 Q16527,P09493,P10644 3 +Entry into host 0.6558306735580245 1.4028259851713976 0.1606687362430165 1.0 0.4281379551029828 33 P07858,P08195,P11279,O15118,Q14108,Q8WTV0,Q9BTY2,Q9Y624,P02786 9 +Myeloid leukocyte migration 0.6603841695265968 1.3999017972499537 0.1615427277868675 1.0 0.4294173776612934 25 Q08722,Q99538,P78310,Q07021,O94813 5 +Establishment of protein localization 0.3127693535203484 1.3992982633445723 0.1617235602093387 1.0 0.429653389518966 563 Q99523,Q10713,P56589,P98164,Q06481,P57737,O00410,Q9P258,P02786,Q07954,Q8TEX9,P15311,O95071,Q9Y5K6,Q14108,Q9HAS0,Q9H3S7,P19021,P50897,Q15904,Q96MW5,Q8NC96,P10619,P13473,P11279,P52789,P27105,A6NIH7,Q8WUX9,Q8NFH5,P63241,Q9BUR4,Q9NQ11,P43034,P31749,Q9P0I2,P11233,Q96GC9,Q9UBF2,Q99747,Q92688,Q9BRG1,Q9UL25,P50416,O60831,Q05D32,Q15154,Q8N4H5,Q9H1Z9,Q8TD16,Q15629,Q15334,P49321,Q86VS8,O15118,P63104,Q13190,Q9BUN8,Q9Y3C0,Q9H173,O43752,P46060,P24390,P21359,O60830,Q9Y6B6,P68036,Q92544,P42566,P05026,Q96D46,Q9H2M9,Q15070,Q9BXS5,Q96C92,P35606,P04083,P35580,P04114,P31751,P60953,Q9NV96,Q15006,O43731,Q96BM9,P60520,O15260,P60604,O75381,O15400,P43307,Q8NFH3,Q9UI26,Q9Y496,Q9UPT5,Q9Y512,Q5JRX3,O15078,Q15041,O43707,O94979,P14923,O00560,P40763,Q9BW27,Q9UN37,Q96RT1,Q6UWE0,Q92572,Q96ES7,Q9NVU7,O60645,Q13277,Q9NVZ3,Q16539,P20645,P55786,P84085,Q99595,O60784,P62258,Q9Y282,P40855,Q86Y82,Q14168,Q5JRA6,O96028,Q9H4M9,P46934,P46379,P31946,O95831,Q4J6C6,O15126,Q8TAG9,O15027,Q12907,Q9Y3E7,O43464,P19784,Q92783,Q8N183,P53350,Q13555,Q32P28,P06493,Q9ULC3,O14828,Q04917,O95486,O75915 151 +Schwann cell development 0.653776807514833 1.3983014149689723 0.1620225731552174 1.0 0.4301659670638112 10 P21359,Q93074,P31749 3 +Cell recognition 0.6588984603157794 1.3958955557309392 0.1627459491812617 1.0 0.4313827887500056 27 Q9BY67,Q5KU26,P05067,Q8WTV0,Q08431 5 +Positive regulation of peptidyl serine phosphorylation 0.6582390570453819 1.3956061789156675 0.1628331207391535 1.0 0.4314381831550222 16 P05067,P02786 2 +Glucose import 0.6578305794781812 1.3935758825994604 0.1634457155772044 1.0 0.4315766350665362 16 Q06481,Q99523,P31751,P31749 4 +Long chain fatty acid biosynthetic process 0.6422668240850011 1.3932441070636357 0.1635459860826302 1.0 0.4315766350665362 3 Q96PU8,P28161 2 +Autophagic cell death 0.6403068751844244 1.3931152246760603 0.1635849499259434 1.0 0.4315766350665362 2 Q9Y371 1 +C terminal protein amino acid modification 0.6403068751844243 1.3931152246760587 0.1635849499259438 1.0 0.4315766350665362 2 O60725 1 +Autophagy of nucleus 0.6403068751844243 1.3931152246760587 0.1635849499259438 1.0 0.4315766350665362 2 Q9NT62 1 +Cellular response to nitrogen starvation 0.6403068751844088 1.393115224675986 0.1635849499259658 1.0 0.4315766350665362 2 P60520 1 +Positive regulation of endocytosis 0.659094646273888 1.3923197137564778 0.1638256044204196 1.0 0.4317503334428221 20 Q06481,Q07954 2 +Positive regulation of stem cell proliferation 0.6434961208817949 1.390361480751764 0.1644191371062211 1.0 0.4326469614234032 4 O95251 1 +Phospholipid transport 0.656936864639493 1.3891332686573457 0.164792228954836 1.0 0.433103516550659 16 Q9NV96,Q14108,Q8WTV0,P61916,Q96GC9,P08183 6 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.6431384705907232 1.388667984820935 0.164933733777723 1.0 0.4332953624432327 4 Q9BY67,P78310 2 +Fat soluble vitamin metabolic process 0.6493200175226918 1.388455647097624 0.1649983415509637 1.0 0.4332953624432327 8 Q99538,P98164 2 +Ribosome associated ubiquitin dependent protein catabolic process 0.6428471488371127 1.3872884864112622 0.1653538125179237 1.0 0.4337039965719916 4 Q9H1I8 1 +Phagocytosis 0.6436853191470883 1.3863566193487171 0.1656380358904321 1.0 0.4341076103936859 40 Q08722,Q5KU26,P51790,Q8WTV0,Q92544,Q06481,Q08431,Q07954 8 +Cellular response to calcium ion 0.6509255520302746 1.3844931815994324 0.166207494451223 1.0 0.4353961390290858 10 Q99538 1 +Lipoprotein metabolic process 0.6568147858764248 1.382039017075359 0.1669597213398508 1.0 0.4358108033725506 19 P04114,Q9H490,Q16739,P06756,P04062,P50897 6 +Negative regulation of map kinase activity 0.6473723717700562 1.3790957519730946 0.1678652334451373 1.0 0.4374710447269193 8 P04062 1 +Osteoclast differentiation 0.6492525909120542 1.3763883025589725 0.1687014475360639 1.0 0.4384217259320465 10 P21359,Q15904,P02786 3 +Maternal process involved in female pregnancy 0.6500807320501943 1.375145921894862 0.1690862098739955 1.0 0.4390710914558082 11 P07858,P19021 2 +Modification of synaptic structure 0.6474596597816656 1.37340921778347 0.1696251657725298 1.0 0.4395938810426629 9 P60953,Q7L576,P61586,O00264,Q9UQB8 5 +Positive regulation of neuron projection development 0.6523149923751227 1.370052259816196 0.17067058883551 1.0 0.4417070876754405 30 P23229,Q9NV96,Q9H4M9,Q14108,Q9UJU6,Q32P28,Q14444,Q9NUM4,Q9UQB8,P08069,P61160 11 +Membrane repolarization 0.6434875383391528 1.366994574546978 0.1716270060899258 1.0 0.4438982159894388 7 P54709,O75844,P62258 3 +Regulation of toll like receptor signaling pathway 0.6465536995102464 1.3633088322915423 0.1727851996100966 1.0 0.4463488859909397 10 Q06481,O75955,Q9NPR9 3 +Regulation of camp dependent protein kinase activity 0.639433364263359 1.3626737159754438 0.1729853650476065 1.0 0.4464973318895658 5 P10644,P23634 2 +Iron ion homeostasis 0.6511024067193902 1.3601147025681255 0.1737936291456385 1.0 0.4475460940419727 16 P61421,Q9NQ11,Q15904,Q92859,P02786 5 +Positive regulation of protein kinase b signaling 0.6515656610439298 1.3596946416040618 0.173926574496539 1.0 0.4477113483481491 17 P05556,Q99829,Q13641,P98164,P08069,Q07021 6 +Regulation of cellular component biogenesis 0.3306495297032127 1.3594311401647603 0.174010008993201 1.0 0.4477475085721536 228 Q08722,Q96AC1,Q15375,Q9UQ16,Q7L576,P05067,Q13641,P04062,Q04656,Q9UJU6,Q96ST3,Q8NEY8,O15511,Q9Y624,Q9P258,P02786,Q9Y6B6,P15311,Q9Y3E7,Q8TBX8,Q9P2S5,Q92783,O43293,O94813,Q15555,P53350,Q9UBB9,Q16181,P61160,Q14203,P41440,Q9UNN5,P58546,Q9NQ11,P09493,P11234,O75955,O00560,Q9UQB8,Q9UN37,Q6UWE0,Q9Y3P9 42 +Regulation of exosomal secretion 0.6463434473821755 1.3569574056268623 0.1747947449243057 1.0 0.4488811792730691 11 Q9Y3E7,Q9UN37,O00560,Q9NQ11 4 +Attachment of gpi anchor to protein 0.6378820000369549 1.3552952564157466 0.1753235057374456 1.0 0.4490480331458935 5 Q9H490 1 +Regulation of peptidase activity 0.464701845688689 1.3549130969588643 0.175445246384184 1.0 0.4490480331458935 87 Q15375,P07858,Q9NQ11,Q99538,P05067,Q15041,Q15392,P31749,Q06481,Q92542,Q07954 11 +Positive regulation of bmp signaling pathway 0.6394245844679587 1.3545701722226464 0.1755545421000546 1.0 0.4490480331458935 6 Q92859 1 +Sodium ion transport 0.6515196959238401 1.3537592464486208 0.1758131994379712 1.0 0.449369426125321 25 Q9H2J7,P08195,P54709,P46934,Q9UNF1,P31749,Q04917,P27105 8 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.6334120425029469 1.351436247816333 0.1765557289710653 1.0 0.4510901866568426 3 Q7Z6Z7,O95140 2 +Carbohydrate derivative transport 0.6500202802526545 1.3496387397561476 0.1771318913742412 1.0 0.4522072991554158 18 Q08722,P61916,P07602 3 +Cellular response to dsrna 0.6433332879459953 1.3476954302789128 0.177756362465729 1.0 0.4532682803180164 10 Q9NUD5,Q5KU26,O75955,P41440 4 +Sterol homeostasis 0.6455786448796204 1.3437505485598629 0.1790290654367412 1.0 0.4542558717851844 13 P04114,Q9H4M9,O15118,Q8WTV0,P61916,Q5BJF2,O95486 7 +Sodium ion transmembrane transport 0.649569865602388 1.3430053338156187 0.1792702467393618 1.0 0.4542558717851844 21 Q9H2J7,P08195,P54709,P46934,Q04917,P27105 6 +Sulfur compound catabolic process 0.6423143716365709 1.3427540818076382 0.1793516163724846 1.0 0.4542558717851844 10 P15586,Q9UJ14,Q8WUX2,P16278 4 +Skeletal system morphogenesis 0.6491690891116068 1.3419802837033803 0.1796023885413198 1.0 0.4542558717851844 20 Q16539,Q93074,Q93063,Q9NX62,Q8N5W9,Q92896,Q9ULC3 7 +Modification of postsynaptic structure 0.6380697553300757 1.3410344160191106 0.1799092788499714 1.0 0.4542558717851844 7 Q9UQB8,Q7L576,P60953,P61586 4 +Lipopolysaccharide mediated signaling pathway 0.6393110842268045 1.3403269230768604 0.1801390822104926 1.0 0.4542558717851844 8 Q8WTV0,P31749 2 +Positive regulation of hydrolase activity 0.3802523017950354 1.334273261154679 0.1821143173481343 1.0 0.4569539420991804 100 Q96AC1,P05556,P07602,Q96N67,P05067,Q9Y624,Q9P258,P21359,Q8IZ81,Q96HY6,Q99538,O43464,P61586,Q15555,P23229,P31751,P26583,P31749,Q9NUM4,Q92542,P40763,O75915,Q9Y3P9,O95831 24 +Notch signaling pathway 0.6465976545005819 1.332437412151234 0.182716495211257 1.0 0.4578461831506093 18 Q92542,P05067,P40763,P31749 4 +Regulation of phagocytosis 0.6464582995798765 1.3317368890057637 0.1829466628670046 1.0 0.4582038139725882 18 Q08722,P06756,Q8WTV0,Q06481,Q08431 5 +Visual behavior 0.635910686082244 1.3306839946077746 0.1832930116404634 1.0 0.4582325291011585 7 P21359,P05067 2 +Regulation of postsynapse organization 0.6460362107510664 1.3296150194199383 0.183645146958725 1.0 0.458936624453474 18 Q15375,Q9UQ16,P19022,Q14444,Q9UQB8,P61160 6 +Cognition 0.6379763262811236 1.329373837109702 0.1837246650097925 1.0 0.4589591593299116 37 Q99538,P17900,P05067,Q13641,P50897,Q11206,Q92542 7 +Membrane repolarization during cardiac muscle cell action potential 0.6302595981460218 1.3276276227478234 0.1843011545245692 1.0 0.4599400467145567 4 P62258 1 +Membrane repolarization during action potential 0.6302595981460218 1.3276276227478234 0.1843011545245692 1.0 0.4599400467145567 4 P62258 1 +Postsynaptic specialization organization 0.6279560461024805 1.3256512670541714 0.1849552363975553 1.0 0.4611961850907824 3 P19022 1 +Cellular component maintenance 0.6399033074441969 1.3255934894257055 0.1849743839127546 1.0 0.4611961850907824 11 Q96AC1,P56545,Q9BRK5,P08069,Q14203 5 +Anatomical structure maturation 0.6420286507119002 1.3227361521923016 0.1859231365421876 1.0 0.4623222379257606 32 P21359,P04062,P05067,O75503,O75787,Q8N5W9,P11413,Q9Y2W6,Q15125 9 +Neutral lipid biosynthetic process 0.6326263622999071 1.3221038299454038 0.1861335786287337 1.0 0.4626688036934159 6 Q8NCC3 1 +Anion transport 0.5278892598204464 1.3189321037124306 0.1871918122270413 1.0 0.4645896674029884 74 Q9H813,Q08722,P05556,P30825,P07602,Q9C0H2,Q9UBX3,P08195,Q14728,P98164,P21359,Q9H2J7,P51797,P04083,P51790,Q7L0J3,Q9UHG3,Q15041,P51798 19 +Lipid localization 0.4775790977138695 1.3178340039732197 0.1875592221574253 1.0 0.4648507901807642 84 P07602,O15118,P17900,P04062,P08183,Q07954,Q9Y6B6,Q9C0B1,Q14108,Q8WTV0,P04083,P04114,P31751,Q9NV96,P07686,P61916,Q86Y82,O15260,Q99720,Q16739,Q9H4M9,P06756,P31749,Q96GC9,Q9UN37 25 +Regulation of protein complex stability 0.6279893711248957 1.3168577869524218 0.1878862984621574 1.0 0.4651423172860161 4 Q969V3,Q7Z392,Q9BQ95 3 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.6279715555372638 1.3167732611613865 0.18791463816624 1.0 0.4651423172860161 4 O60573,P40763 2 +Respiratory system process 0.6337115410930931 1.3133745181094865 0.1890567796599542 1.0 0.4667272034836185 8 Q9BT17,P10253,Q9C0B1 3 +Regulation of cell adhesion 0.3920151956248717 1.3126219157275998 0.1893103810106553 1.0 0.4670953469223908 98 Q08722,Q96AC1,Q15375,Q9NUQ9,Q13277,P30825,Q14254,Q9Y624,Q9P258,P02786,P21359,Q16539,Q9H3S7,P61586,O43293,Q07021,P04083,Q5JRA6,Q11206,P04439,P41440,Q9UNN5,P06756,P52565,P09493,P10644,O75955,P31749 28 +Vascular transport 0.6400699904824344 1.3124369476897253 0.1893727473025699 1.0 0.4670953469223908 14 P41440,P30825,P98164,P08183,P23634,P02786,Q07954 7 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.5030878985987046 1.3120403210939469 0.1895065302656813 1.0 0.4670953469223908 79 Q15375,Q99523,P31751,Q99538,Q8TBX8,P31749,Q92572,Q9UQB8,P40763,Q9BRG1,P08069,P11717,Q07954 13 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.6304567532379897 1.311737341642734 0.1896087727697719 1.0 0.4670953469223908 6 P21359,O43464 2 +Early endosome to golgi transport 0.6286681171368176 1.3114444149748845 0.1897076615346369 1.0 0.4670953469223908 5 Q13190 1 +Vascular process in circulatory system 0.6388559136876084 1.3101290055132446 0.1901521975486493 1.0 0.4677913153967135 33 Q96AC1,P41440,Q9UDY2,P30825,Q93063,Q9HB40,P61586,P98164,P42892,P08183,P23634,O94813,P02786,Q07954 14 +Negative regulation of atp dependent activity 0.6298209110509877 1.3086988577576528 0.1906363788032441 1.0 0.4677913153967135 6 Q15070 1 +Podosome assembly 0.6280738705788155 1.3086148230469847 0.1906648572406972 1.0 0.4677913153967135 5 Q9UJU6 1 +Epithelial cell differentiation 0.3641156872339041 1.3070744895187183 0.1911874142799221 1.0 0.4686107179827911 102 P04083,P07858,Q9UDY2,P31751,P07602,Q13510,P31749,P15291,O14773,O43598,Q9Y624 11 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6396854452792322 1.3066930009755675 0.1913169966717376 1.0 0.4687518435577764 15 P98164,Q92896,Q07954 3 +Positive regulation of synaptic transmission 0.6421644053735396 1.30641363349067 0.1914119320023668 1.0 0.4688080050170835 20 P21359,Q13277,Q99538,P05067,Q14168,Q92542 6 +Serine family amino acid biosynthetic process 0.6318810333258067 1.3045604084910591 0.1920425770688369 1.0 0.4698223136858808 8 P00374 1 +Establishment of protein localization to vacuole 0.6416956090861424 1.3040323201809183 0.1922225628179692 1.0 0.4699094569827186 20 Q99523,P13473,P46934,Q14108,P20645,Q9BRG1,Q9UN37 7 +Neural retina development 0.6312997944680044 1.3017613787357212 0.192997970129954 1.0 0.470744393235669 8 Q15555,P54802 2 +Protein kinase c signaling 0.6244548147631647 1.3000854777679378 0.1935716743894349 1.0 0.4714936919679037 4 O75955 1 +Positive regulation of dopamine receptor signaling pathway 0.6205370315727208 1.3000177800259414 0.1935948753656231 1.0 0.4714936919679037 2 O14744 1 +Regulation of dopamine receptor signaling pathway 0.6205370315727208 1.3000177800259414 0.1935948753656231 1.0 0.4714936919679037 2 O14744 1 +Positive regulation of molecular function 0.3229593712493129 1.2988754219724583 0.1939866856771051 1.0 0.472271250470439 303 Q96AC1,Q15375,P05556,O15111,P07602,P54709,Q04656,P05067,Q9UBS4,P0CG13,O75503,Q96N67,P08183,P23634,Q9BRX5,P08069,Q9Y624,Q9P258,P02786,Q07954,P21359,Q8IZ81,Q16539,Q96HY6,Q99538,O43464,Q8WTV0,Q96D46,Q8IXB1,Q15555,P23229,P53350,P31751,P62942,P56545,Q8NDZ4,Q9Y2B0,Q00403,Q9BTE7,P00374,P41440,P58546,P09493,P26583,O75955,P11234,P31749,Q15185,Q96GC9,Q9NUM4,P31946,P40763,O60934,O95831,O75915,Q9Y3P9,Q92542 57 +Protein autoprocessing 0.6257196855666679 1.297403616497216 0.1944923488311212 1.0 0.4731484270891625 5 P17655 1 +Amyloid fibril formation 0.6287754739181545 1.2964619312475631 0.1948163873685646 1.0 0.4735144141047061 7 P05067,P62942 2 +Response to catecholamine 0.6380638320558114 1.2951839534831702 0.1952567789903763 1.0 0.4739977166647781 16 Q96ST3,P05067,Q92542,P29992 4 +Detection of biotic stimulus 0.6232887967233627 1.2945513695117556 0.1954750375691758 1.0 0.4742983580228605 4 P01889,Q8WTV0 2 +Macroautophagy 0.3425758962337673 1.2934060139406949 0.1958706712232465 1.0 0.4749681047605413 108 O15118,P04062,P07384,Q9Y3E7,Q8TBX8,O43464,P68402,Q92783,Q93050,Q96HS1,P61421,P13473,Q9Y487,Q86Y82,Q9ULC3,Q9NQ11,P46934,P11234,P31749,Q96GC9,Q9BRG1,Q9UN37,Q6UWE0 23 +G protein coupled receptor signaling pathway involved in heart process 0.6207294667848308 1.2914766540766978 0.1965384453619205 1.0 0.4754647473464632 3 P23634 1 +Cell maturation 0.6397029206522581 1.291472063746466 0.1965400361151048 1.0 0.4754647473464632 23 P04062,P05067,O75503,P11413,Q9Y2W6 5 +Metencephalon development 0.6375312528715898 1.290744016630465 0.1967924561341423 1.0 0.4756607425504135 30 P58546,Q5KU26,Q04656,P04062,P54802,Q9BRK5,P08069,Q92542 8 +Positive regulation of smoothened signaling pathway 0.6289836176553567 1.2906062375749978 0.1968402519863001 1.0 0.4756607425504135 8 Q86SX3,Q7Z3E5 2 +Inner cell mass cell differentiation 0.6184715255237575 1.2902800269626988 0.1969534490395714 1.0 0.4757576820955881 2 Q6PD62 1 +Negative regulation of canonical wnt signaling pathway 0.6362666677310753 1.289735257876303 0.1971425934513933 1.0 0.4760379389349296 15 P19022,Q13641,Q16539 3 +Cellular carbohydrate catabolic process 0.6380277932309376 1.2893380451357592 0.1972805899443492 1.0 0.4761945274518775 18 Q14108,P10253 2 +Glial cell differentiation 0.6234956971541661 1.288940471319819 0.197418782667504 1.0 0.4763460220635894 42 P21359,Q13144,P31751,Q9UPY3,Q93074,P19022,P04062,P05067,P31749,P40763,Q92542,Q07954 12 +Determination of adult lifespan 0.6270085050748755 1.2879839246367135 0.1977515590860081 1.0 0.476624453776347 7 P04062 1 +Low density lipoprotein particle clearance 0.632895737879913 1.2862289344764828 0.1983631757867352 1.0 0.4770505562564218 12 P38571,P04114,Q8WTV0,Q9H4M9 4 +Metal ion transport 0.3413512007169285 1.280873597911247 0.2002380677669524 1.0 0.4799520696475921 107 P05556,P08195,P54709,Q04656,Q9UNF1,P98164,P02786,Q9H2J7,P11413,Q13555,P62258,P62942,P13693,Q8TAD4,P27105,Q9NWR8,P35670,P06756,P46934,P31749,Q04917,Q96GC9,O75844 23 +Energy homeostasis 0.6214791993360711 1.2772044736858237 0.2015300679918681 1.0 0.4820737494915657 5 P42785 1 +Regulation of neuron projection development 0.5131355490301309 1.2748493687129396 0.2023625628293921 1.0 0.4836197812112124 76 Q15375,Q9UQ16,Q7L576,Q9UJU6,P08069,P10586,Q14108,P61586,Q14444,O94813,P23229,Q13555,Q9NV96,Q32P28,A0MZ66,Q86X55,P61160,P39880,Q96G23,Q9H4M9,P46934,P19022,P43034,P31749,Q04917,Q9NUM4,Q9UQB8,Q9UL25 28 +Negative regulation of inflammatory response to antigenic stimulus 0.6190550135109603 1.2744534574640511 0.2025027573100453 1.0 0.4837772293902366 4 P28070 1 +Regulation of epithelial to mesenchymal transition 0.6223158402639526 1.2728232020933603 0.2030807859221601 1.0 0.4842695664297665 6 O00560 1 +Taxis 0.555040243976925 1.2712622237191176 0.20363537666698 1.0 0.4850590201617417 66 Q15375,P04083,Q13277,Q99538,P05067,Q13641,P42892,Q07021,P78310,Q92859,O94813 11 +Gamete generation 0.3406140135849851 1.270812872716223 0.2037952280862176 1.0 0.485084802501381 107 P05556,P23634,P11717,Q9UQR1,Q9UHI6,P19784,P68402,P78310,Q14671,P53350,Q9BY67,P04114,O14777,P07686,Q8NB78,Q9UHI8,Q16181,P26583,P31749,Q9GZP4,P46379,Q9Y2W6 22 +Stress granule disassembly 0.616292798110974 1.2704865304197348 0.2039113778165826 1.0 0.4851391851889687 3 Q07866,P33176 2 +Neurotransmitter uptake 0.6217666920238425 1.2701974991350744 0.2040142882638369 1.0 0.4851391851889687 6 P41440,P05556,O75955 3 +Transition metal ion homeostasis 0.6345216542603932 1.2693033645559642 0.2043328868270977 1.0 0.4856542874203746 28 P61421,Q9NQ11,Q9Y487,P35670,Q04656,P05067,Q15904,Q92859,P02786 9 +Endocrine process 0.6228930977516604 1.268234248623186 0.2047143097864794 1.0 0.4862058214921492 7 P42892,O75787 2 +Negative regulation of dephosphorylation 0.6280731204552571 1.2679272253947669 0.2048239405121883 1.0 0.486246997472314 11 P62258,P62942,Q15257,Q13464,P31946,Q9UHD1,O75116 7 +Negative regulation of cell morphogenesis involved in differentiation 0.6151849137905534 1.265244302598811 0.2057837656833869 1.0 0.4880336300906554 3 Q9P258 1 +Embryo development 0.3289853421716494 1.2637625374974686 0.2063152711827862 1.0 0.4887679445721898 208 P05556,Q9BZK7,Q04656,Q9H9B1,Q16706,P98164,P42892,Q8IWS0,O60921,O75787,Q96EK5,P21359,Q14574,Q93074,P54802,P36896,Q9Y6I3,P04114,P67809,Q9NX62,Q14168,Q16181,P06756,Q93063,P10644,P31749,P46379,Q13572,O60934,P17655,Q9Y2W6 31 +Positive regulation of synaptic vesicle recycling 0.6166261618439421 1.2629215018608129 0.2066173917505769 1.0 0.4889419194097621 4 Q9UQ16 1 +Cell cell signaling 0.3311859438663236 1.2585063559542753 0.208208690016062 1.0 0.4921708685564865 199 Q96AC1,P05556,Q13277,Q9BZK7,Q9UIQ6,Q9P1Z2,Q7L576,P05067,Q13641,Q5SQN1,O75787,Q07954,P21359,O95071,Q16539,Q9Y4J8,Q99538,Q93074,Q99471,Q9H3S7,P61586,P19784,O43293,P50897,P78310,Q8N183,P04083,Q8TAA9,Q13555,P51790,Q7L0J3,Q9NWU2,P56545,O60333,Q14168,P41440,Q9UBB6,P19022,O75955,P31749,Q04917,O00560,Q9UQB8,P29992,Q92542,Q4J6C6 46 +P38mapk cascade 0.6155525019398248 1.2578234943341975 0.2084555969308172 1.0 0.492575657357394 4 Q16539 1 +Cardiac ventricle development 0.6295986792926346 1.256648952611575 0.2088807803061017 1.0 0.4934012626243548 15 Q13308,P09493,P62942,P98164,O75844,Q9ULT8,O96028,O94813 8 +Positive regulation of endothelial cell proliferation 0.624442823678522 1.2560041777064537 0.2091144554109567 1.0 0.4937740677277216 10 P21359,Q9H2J4,P40763,P31749 4 +Regulation of myotube differentiation 0.618389857202697 1.2540500723956545 0.2098238060244917 1.0 0.4942650094368034 6 Q9BYT8 1 +Regulation of carbohydrate catabolic process 0.6282183339493563 1.2539023511809435 0.2098775003481383 1.0 0.4942650094368034 14 Q14108,P05067 2 +Positive regulation of exosomal secretion 0.6239389243120037 1.2535567265391605 0.2100031682977376 1.0 0.4942650094368034 10 Q9UN37,O00560,Q9NQ11 3 +Mesoderm morphogenesis 0.6197223722920321 1.2530153458404694 0.2102001219504972 1.0 0.4942650094368034 7 Q93063,P10644 2 +Negative regulation of phosphatase activity 0.619716141162117 1.2529854358305148 0.2102110070720662 1.0 0.4942650094368034 7 O75116,P62942,Q15257,Q13464 4 +Positive regulation of vacuole organization 0.621136888013797 1.2528029368533709 0.210277432590431 1.0 0.4942650094368034 8 P48426,P11234,Q8TBX8,Q15042,Q9H2M9,Q6UWE0 6 +Dopamine receptor signaling pathway 0.6196184596401876 1.2525165545904124 0.2103816999048229 1.0 0.4942650094368034 7 Q92542 1 +Positive regulation of neurotransmitter transport 0.6124050630725903 1.2520897731298977 0.2105371537892866 1.0 0.4942650094368034 3 P05556 1 +Positive regulation of stress fiber assembly 0.6257547962237987 1.2512594723244523 0.2108398264925317 1.0 0.4947971414803106 12 Q08722,Q96AC1,P60953,P35080,P09493,P61586,O75116 7 +Protein localization to nucleus 0.3421507569098385 1.2503485899626527 0.2111722357997967 1.0 0.4952201927437596 120 Q96AC1,Q9UH99,Q96ST3,Q06481,O00410,P02786,Q8TEX9,P21359,O95071,Q16539,Q96D46,P53350,P51858,P62258,O95251,P06493,Q9ULC3,Q9NQ11,P31749,O14657,P40763 21 +Actin cytoskeleton reorganization 0.6315107882706187 1.2490635456541666 0.211641832638264 1.0 0.4957856532835909 24 P04083,P15311,Q13308,Q9Y5K6,P52565,P61586,P11233,O43293,Q9UQB8,P78310,Q13576,Q9Y624 12 +Plasma lipoprotein particle clearance 0.6259354309202214 1.247183113649549 0.212330363144638 1.0 0.4966836737591066 13 P38571,P04114,Q8WTV0,Q9H4M9 4 +Defense response to other organism 0.3407993426250213 1.2463532397978507 0.2126347401016284 1.0 0.4972150585393715 156 Q08722,P10321,O15111,Q06481,O00584,Q9NZ08,Q8IZ81,Q5KU26,Q9Y3E7,P01889,O43293,Q14671,Q07021,P04083,Q9BY67,P11279,P61160,Q7Z739,P04439,Q9NUD5,Q6UWE0 21 +Regulation of superoxide metabolic process 0.6149253565837909 1.2459771863410978 0.2127727707964932 1.0 0.4972150585393715 5 P00374,Q9NY61,Q05655 3 +Granulocyte migration 0.6286683951072318 1.2422349426696475 0.2141498907950059 1.0 0.4994101513760111 18 O94813,Q07021,P78310 3 +Negative regulation of bmp signaling pathway 0.6156977025045467 1.2411754024282002 0.2145409594619953 1.0 0.4998146003137605 6 P98164 1 +Response to pain 0.6117262545491338 1.2396542263742891 0.2151033144365071 1.0 0.5002297840834729 4 P31749 1 +Behavioral response to pain 0.6117262545491338 1.2396542263742891 0.2151033144365071 1.0 0.5002297840834729 4 P31749 1 +Adult behavior 0.6293205867894781 1.2396060899914654 0.2151211270258493 1.0 0.5002297840834729 21 Q92542,P05067,P50897,P51790 4 +Hindbrain morphogenesis 0.620489365152705 1.236801194619789 0.2161608984763261 1.0 0.5017377049290935 10 Q04656,P04062 2 +Retrograde transport vesicle recycling within golgi 0.6140893278639118 1.233483379724689 0.2173954738151606 1.0 0.5040044638663448 6 Q96MW5,Q9Y2V7,Q8TBA6 3 +Negative regulation of peptidyl lysine acetylation 0.6170800690790289 1.2332539454403468 0.2174810345236966 1.0 0.5040233302774172 8 Q9BX68,Q01105 2 +Gpi anchor metabolic process 0.6136086908168364 1.231184718526107 0.2182537854995914 1.0 0.5052745887632788 6 Q9H490 1 +Scf dependent proteasomal ubiquitin dependent protein catabolic process 0.615002133221954 1.2303565729985584 0.2185636079422228 1.0 0.505811975721248 7 Q13619,Q13620,Q9Y297 3 +Regulation of intracellular signal transduction 0.3186897987707085 1.2299598820635125 0.2187121282192701 1.0 0.5059170713823706 276 Q9NUQ9,Q96AC1,Q8TD19,Q15375,P05556,Q10713,O15111,P18615,O60313,P63104,P04062,P05067,Q13641,P23396,P98164,O75787,P60866,Q9H4H8,P23634,P08069,Q9UNS2,Q9Y624,P02786,Q13619,P21359,P15311,Q16539,Q9Y5K6,O43464,P61586,P16989,Q9Y4E8,Q14671,Q07021,O94813,Q15555,Q9H3F6,Q96KB5,Q9Y297,Q96S59,Q7LG56,O14777,P62942,P13693,Q68EM7,Q6IAA8,O43567,Q8NDZ4,P63241,Q9NUD5,P41440,Q8WVQ1,Q99829,O75489,P06756,P52565,P46934,P43034,P19022,P31749,O75955,O00560,O75915,O75844 64 +Response to aldosterone 0.6095060506776888 1.2291108892413811 0.2190302329791829 1.0 0.5059170713823706 4 P08069 1 +Hemoglobin metabolic process 0.6054883446444246 1.2290487099740677 0.2190535436607477 1.0 0.5059170713823706 2 Q99873 1 +Hemoglobin biosynthetic process 0.6054883446444246 1.2290487099740677 0.2190535436607477 1.0 0.5059170713823706 2 Q99873 1 +Regulation of hemoglobin biosynthetic process 0.6054883446444246 1.2290487099740677 0.2190535436607477 1.0 0.5059170713823706 2 Q99873 1 +Regulation of organic acid transport 0.6222372949562044 1.228990672373352 0.2190753032606609 1.0 0.5059170713823706 13 P05556,P31751,Q7L0J3,Q15041,P31749 5 +Regulation of amino acid transport 0.6145992969965594 1.228422757456257 0.2192883092261315 1.0 0.5062293947028781 7 P05556,Q7L0J3,Q15041 3 +Amino acid transport 0.6267150207581084 1.2262916648313091 0.2200889368724397 1.0 0.5076065017850154 21 P21359,Q9H2J7,P05556,P08195,Q7L0J3,Q15041,Q6P4A7 7 +Regulation of presynaptic cytosolic calcium ion concentration 0.6068791921211785 1.2259384708718262 0.2202218302237217 1.0 0.5076643465851376 3 P23634 1 +Hindbrain development 0.6215161900967192 1.2249571088209952 0.2205913813064843 1.0 0.5083362450637923 35 P58546,Q5KU26,Q04656,P04062,P54802,O14949,Q9BRK5,P08069,Q92542 9 +Negative regulation of hydrolase activity 0.5554316212707378 1.2216443771874257 0.2218421391425162 1.0 0.5106828100173042 64 P04083,P07858,Q99523,P05067,Q15392,P31749,Q06481,Q9Y624,Q07954 9 +Neuron projection organization 0.6262278542014729 1.2216368004265434 0.2218450056419256 1.0 0.5106828100173042 24 Q9UQ16,Q99538,Q9UJU6,P05067,Q14444,Q9UQB8,P08069,P61160 8 +Regulation of cell shape 0.6244606010460704 1.2205265133518488 0.2222653449884242 1.0 0.5110457093015236 30 Q96AC1,P04083,P15311,P09493,Q7L576,P07686,O43293,Q16181,Q9UQB8,O75844,Q9Y624 11 +Regulation of nitric oxide synthase activity 0.6158058114573327 1.2203910757547327 0.2223166587929208 1.0 0.5110457093015236 9 Q8WTV0,P31749,P06280 3 +Positive regulation of response to external stimulus 0.5747881958089492 1.2196535538604354 0.222596235642638 1.0 0.5113041559764847 58 Q08722,Q9NUD5,Q9BY67,Q13277,Q99538,P11279,P05067,Q13641,P08069,Q6UWE0,Q07021,O94813,P53634 13 +Body fluid secretion 0.622847276746213 1.2193225502559015 0.2227217929592231 1.0 0.5113041559764847 16 P35670,Q04656,Q9UNS2,P00403,P19021,Q99808 6 +Regulation of rig i signaling pathway 0.6141108102769338 1.2189451392614836 0.2228650155142131 1.0 0.5113041559764847 8 Q14671,Q9NUD5,Q07021 3 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6141108102769338 1.2189451392614836 0.2228650155142131 1.0 0.5113041559764847 8 Q14671,Q9NUD5,Q07021 3 +Regulation of rac protein signal transduction 0.6069836442866613 1.2171324500642051 0.223553826034879 1.0 0.5124420448898108 4 P21359 1 +Negative regulation of erbb signaling pathway 0.6133340549999582 1.2152019959415137 0.2242890593729116 1.0 0.5137655793517434 8 Q99538 1 +Cellular response to cadmium ion 0.6104563070137482 1.2085345461718693 0.2268417159341744 1.0 0.51724678484465 7 Q04656,P31749 2 +Pathway restricted smad protein phosphorylation 0.6086524992813588 1.2074818185746852 0.2272466428397499 1.0 0.517626187854014 6 O00560,Q07954 2 +Secondary metabolite biosynthetic process 0.6048085742796805 1.2068037695560974 0.227507724015616 1.0 0.5177426248578241 4 Q9Y4G8,Q04656 2 +Fat cell differentiation 0.6218932676289104 1.206729454822764 0.2275363517232311 1.0 0.5177426248578241 30 Q99523,Q16539,Q9BZK7,Q9C0B1,P31751,Q8N4Q0,P56545,P31749,Q9BRK5,Q86X55,Q9NZ08 11 +Retina homeostasis 0.6045452280223738 1.2055532612308388 0.227989789892784 1.0 0.518050098499834 4 P51790 1 +Photoreceptor cell maintenance 0.6045452280223738 1.2055532612308388 0.227989789892784 1.0 0.518050098499834 4 P51790 1 +Positive regulation of small molecule metabolic process 0.6199007008077929 1.204629295040215 0.2283464422970187 1.0 0.5183177612808898 16 P04083,P05067,P31749 3 +Cellular response to peptide 0.499783040163495 1.2037303997037891 0.2286937984793604 1.0 0.5189252799235401 77 P31751,Q99538,P05067,Q8TBX8,P31749,Q06481,Q9UQB8,P40763,Q92572,Q07954 10 +Regulation of behavior 0.607595459711083 1.2024267914232367 0.2291982142776181 1.0 0.5195265929482221 6 P40763 1 +Receptor metabolic process 0.6173273565760885 1.201723560118934 0.229470649850056 1.0 0.519782160933843 35 Q9UQ16,Q99538,P46934,O75955,P42892,O00560,P07384,P02786,Q07954 9 +Protein deglycosylation 0.6055628882356348 1.201361991368704 0.2296108131726684 1.0 0.51991874565359 5 O00754 1 +Amino acid transmembrane transport 0.6182675799116617 1.2004075552062246 0.2299810960715733 1.0 0.5202367984949673 15 Q9H2J7,P05556,P08195,P30825,Q15041 5 +Protein localization to cell cell junction 0.6098957634432228 1.1986336679721945 0.2306704207910739 1.0 0.5215591487227199 8 Q9Y624 1 +Negative regulation of dna templated transcription elongation 0.6082913470082314 1.1981423491965033 0.2308616045199496 1.0 0.5215591487227199 7 P18615 1 +Developmental process involved in reproduction 0.3387018986127356 1.197915286200003 0.2309499981245497 1.0 0.5215591487227199 143 P04083,Q9BY67,P07858,P04114,Q16539,P07602,Q15392,P07686,P98164,P31749,P15291,Q9GZP4,P68402,Q9UHI8,P11717,Q16181,O94813 17 +Regulation of nitric oxide metabolic process 0.614779000060597 1.1974980488000355 0.2311124876245185 1.0 0.5216165268382265 12 P31749,P06280 2 +Response to zinc ion 0.6094828343972438 1.1966439620636602 0.2314453575894335 1.0 0.5220752868701359 8 Q04656,P19021,Q9NQ11 3 +Cardiac muscle cell membrane repolarization 0.6060985692929182 1.1952685711820268 0.2319821149944498 1.0 0.522894226139755 6 O75844,P62258 2 +Zinc ion homeostasis 0.6076195320680701 1.1949176612986765 0.2321192017968316 1.0 0.522894226139755 7 P35670,Q9NQ11 2 +Neutrophil migration 0.6171560891971813 1.1948908075914533 0.2321296948608129 1.0 0.522894226139755 15 O94813,P78310 2 +Positive regulation of lymphocyte mediated immunity 0.6189391552866489 1.1932569731667355 0.2327687478690325 1.0 0.5237900271785005 18 Q9BY67,P11279,P01889,O15400,P02786,P04439 6 +Proton transporting two sector atpase complex assembly 0.6030545054777081 1.1894100950304052 0.2342783302698541 1.0 0.5256939417626225 5 Q92544 1 +Alpha beta t cell differentiation 0.6131138125954796 1.1893422605917146 0.2343050117797578 1.0 0.5256939417626225 12 P04083,Q04656,P40763 3 +Enteroendocrine cell differentiation 0.6010784183743433 1.1890920691203968 0.2344034389046785 1.0 0.5256939417626225 4 P31749 1 +Myelin maintenance 0.6041140918718637 1.1857793443585265 0.2357094507459836 1.0 0.5276714320345094 6 P31749 1 +Neuron death 0.5109644052668473 1.1847086324309384 0.2361326681776236 1.0 0.528255556644787 74 P21359,Q15375,P51858,P31751,Q9NQ11,Q01105,Q99538,P04062,P05067,O43464,Q15392,P31749,O95831,P50897,Q13564,Q92542,P17655,Q99720 18 +Regulation of lipid catabolic process 0.6080551206007025 1.1828962238081735 0.2368502784161039 1.0 0.529678911882115 9 Q8WTV0,P31749 2 +Cellular response to vascular endothelial growth factor stimulus 0.6034254505436576 1.1824866648724754 0.2370126536536505 1.0 0.5298600189853245 6 P04083,Q16539,P31749 3 +Amine transport 0.6064481091880879 1.182022114785299 0.2371969260932531 1.0 0.5300420150419312 8 P05556,Q7L0J3,Q15041 3 +Positive regulation of alpha beta t cell activation 0.6077599923238054 1.1814687180834984 0.2374165732981836 1.0 0.5302167726144684 9 P04083,P04439 2 +Protein localization to vacuole 0.6184010756540401 1.1810006655853038 0.2376024588957479 1.0 0.5304499339544989 24 Q99523,Q9NQ11,P13473,P46934,Q14108,P20645,Q9BRG1,Q9UN37 8 +Import into cell 0.6171801019181151 1.1790614279269545 0.2383737163870853 1.0 0.5315385328373446 29 P41440,P05556,P31751,P08195,P30825,P54709,Q15041,O75955,P31749,P98164,P23634,O75915,Q6UWE0 13 +Synaptonemal complex organization 0.6023274043889059 1.1772367166526854 0.2391010375397351 1.0 0.5328675210236448 6 P53350,P46379 2 +Ribosomal large subunit export from nucleus 0.6037290179052086 1.176245260774755 0.2394968828215806 1.0 0.5331977335168111 7 Q96D46 1 +Response to lipid 0.3373675086829444 1.174339378601411 0.2402591163299701 1.0 0.5341826664303638 140 P49321,Q9P1Z2,O15118,P04062,O15164,P16278,P08069,P11717,P02786,P68036,O95071,Q96HY6,Q16539,O43464,Q8WTV0,P61586,P19021,O94813,P04083,P04114,Q9Y263,Q86X55,Q99829,P46934,P26583,P31749,Q04917,O00767,Q15185,O95831,Q9GZZ9,P40763,P17655,Q13126,P50416,Q13185,O15173 37 +Regulation of cell death 0.3133162944320171 1.1739482215860433 0.2404157658371386 1.0 0.5342195028533466 345 Q15375,P05556,P07858,Q96AC1,Q04446,O60313,O15118,P04062,Q9C0C9,Q15392,P98164,Q96ST3,Q13564,P08069,P11717,P02786,Q07954,P21359,Q8ND90,P30154,Q96HY6,Q99538,Q9Y3E7,Q9UHI6,O43464,P19784,P61586,P16989,O43293,P50897,Q9BTT0,P53634,P11413,Q07021,O94813,P04083,P23229,P51858,P53350,P31751,Q13144,Q9H3K2,Q13510,P13693,P06493,P15291,P00403,Q8NDZ4,Q7L5Y9,Q99720,Q9UNN5,Q9NQ11,Q9NXR7,Q01105,P06756,P26583,Q15041,P31749,P46379,P17655,O75915,Q9Y6C9,O95831 63 +Embryonic appendage morphogenesis 0.6098182962474742 1.1732031618566563 0.2407143444007322 1.0 0.5344646596346408 12 P42892 1 +Protein localization to plasma membrane 0.496052316269868 1.1729361251142782 0.2408214214556896 1.0 0.5345201001283804 77 P05556,Q13277,P54709,Q14254,Q13641,Q9H223,P23634,Q9ULT8,Q9Y624,Q07954,O15027,P15311,Q13464,Q15904,P31751,O00264,O15400,Q13136,Q8N3R9,P41440,Q9H4M9,P19022,O75955,P31749,Q9UN37,O75915,Q4J6C6 27 +Regulation of dendrite development 0.6167001361158984 1.1727049461281998 0.2409141472681897 1.0 0.5345436600940405 23 P39880,P46934,Q7L576,Q9UJU6,P43034,Q04917,P61586,Q14444,Q9NUM4,Q9UQB8,Q86X55,P61160 12 +Embryo development ending in birth or egg hatching 0.3372287777210133 1.1708343926223148 0.2416653505384085 1.0 0.5360277451465212 139 P05556,Q9BZK7,Q04656,Q16706,P98164,P42892,Q8IWS0,O60921,O75787,Q96EK5,P21359,Q14574,Q93074,P36896,Q9Y6I3,P04114,P67809,P31749,Q13572,O60934,P17655 21 +Cell cell adhesion via plasma membrane adhesion molecules 0.6128267460852223 1.1657196086414665 0.2437278294943707 1.0 0.5389649648207486 17 Q9BY67,Q14574,P05556,Q16539,P19022,O00192,P78310,Q14126,P10586 9 +Organic cation transport 0.5980699325841717 1.165664414993285 0.2437501529420538 1.0 0.5389649648207486 5 Q99808,Q70HW3 2 +Regulation of dendritic spine morphogenesis 0.6091115985618923 1.1644259509749235 0.2442514358994658 1.0 0.5390091009171263 13 Q14444,P61160,Q9UQB8,Q9UQ16 4 +Regulation of potassium ion transmembrane transporter activity 0.6054254810462871 1.1636366582753488 0.2445712888769733 1.0 0.5392053943523923 10 P54709,P46934,P05556,P62258 4 +Sodium ion homeostasis 0.6009882823443677 1.163093827169185 0.2447914363251599 1.0 0.5392053943523923 7 P54709,Q93063 2 +Inflammatory response 0.5208299266368192 1.1630267251445807 0.2448186594900412 1.0 0.5392053943523923 71 Q08722,P04083,Q8IV08,P28070,P04062,P05067,P31749,P15291,Q06481,P40763,P42785,P53634,P38571,Q9Y624,P02786,Q8ND90 16 +Cell surface receptor signaling pathway involved in cell cell signaling 0.470639545234205 1.1616241520358186 0.2453881671465301 1.0 0.5400360331546434 82 Q96AC1,Q9BZK7,Q9P1Z2,P05067,Q13641,O75787,Q07954,O95071,Q16539,Q93074,Q99471,P61586,P19784,O43293,Q99808,Q8TAA9,Q9NWU2,Q14168,P19022,P31749,Q9UQB8 21 +Striated muscle cell development 0.6056154152233089 1.158400808838017 0.2467005092429044 1.0 0.5414768426066445 11 Q16527,P09493,P10644 3 +Neuromuscular process 0.6136515890649129 1.1572415204482096 0.2471736984770027 1.0 0.5421498575085202 27 P17900,P05067,P07686,O14773,P10253 5 +Negative regulation of histone acetylation 0.597897488027183 1.1560606064156411 0.2476563678287129 1.0 0.5426600318293238 6 Q01105 1 +Activated t cell proliferation 0.5986309145875647 1.1517842869658768 0.249409726328502 1.0 0.5438936600511894 7 Q9BY67 1 +Polysaccharide metabolic process 0.6124353887061649 1.1506872757992888 0.2498609131043603 1.0 0.5442907777971631 23 Q7LGA3,Q93063,P31749,O43505,P10253 5 +Regulation of glial cell differentiation 0.6027357934290185 1.1505788197243425 0.2499055506660092 1.0 0.5442907777971631 10 P21359,Q9UPY3 2 +Striated muscle cell differentiation 0.5929253814030153 1.1500339061040603 0.2501299065534472 1.0 0.5442961341877054 46 P05556,Q99523,Q16539,P78310,P11413,Q8IV08,P67809,P06493,Q16527,P41440,P58546,Q9H4M9,Q9BYT8,P09493,P19022,O75955,P10644,P31749,P17655 19 +Regulation of signaling receptor activity 0.6061539040700964 1.1498830159840236 0.2501920570188711 1.0 0.5442961341877054 13 P05067,P07384,Q9BRG1 3 +Positive regulation of dendritic spine development 0.6049887740961815 1.149557779221466 0.250326056184023 1.0 0.5442961341877054 12 Q14444,P61160,Q9UQB8 3 +Neuromuscular junction development 0.6018287016552047 1.1461758039465058 0.251722417303942 1.0 0.5462363050768269 10 P46934,P05067,Q9NQX3 3 +Positive regulation of non motile cilium assembly 0.5957725378109123 1.145905687837561 0.251834177542821 1.0 0.5462363050768269 6 Q16181,Q9P2S5 2 +Cellular response to ether 0.5874889347890275 1.1441756211315373 0.2525508112784327 1.0 0.5462363050768269 2 Q6PKG0 1 +Response to organic cyclic compound 0.3299020852493912 1.143104035454262 0.2529953990094078 1.0 0.5464499162412889 174 P08195,Q9P1Z2,O15118,P04062,P05067,P16278,Q96ST3,P23634,P08069,P15311,O95071,Q96HY6,Q5KU26,P19021,P11413,O94813,P04083,P04114,P49721,P06493,Q86X55,P61160,P00374,Q9NUD5,P41440,Q99829,P46934,P26583,P11234,O75955,Q04917,Q15185,Q9GZZ9,O95831,P40763,P29992,Q13126,O75915,Q92542 39 +Appendage development 0.6088540039923577 1.1425016238885193 0.2532455714328674 1.0 0.5468088457804202 18 P42892,P19021 2 +Positive regulation of cell death 0.3336690203012961 1.138353391716219 0.2549729477428317 1.0 0.5496999695025286 117 Q15375,P05556,P11717,Q8ND90,P21359,Q07954,P30154,Q9UHI6,O43464,P61586,O43293,P53634,Q07021,O94813,P04083,P23229,Q13144,P15291,P00403,Q9UNN5,P17655,O75915,Q9Y6C9,O95831 24 +Ion transmembrane transport 0.3311142191387475 1.1371515680393764 0.2554749294731293 1.0 0.5496999695025286 169 P05556,P08195,Q9UBX3,Q9C0H2,P54709,P30825,Q04656,P05067,Q14728,Q7KZN9,P98164,P08183,P07384,Q9H2J7,Q13423,P51797,Q8NB49,Q70HW3,P11413,P61421,P51790,P62258,P62942,P00403,Q6P4A7,Q8TAD4,P27105,P41440,Q9UHG3,Q9NQ11,Q9NWR8,P35670,P06756,P46934,Q15041,Q04917,P51798,Q96GC9,O75915,O75844 40 +Actin mediated cell contraction 0.6062580495537794 1.1366212164942604 0.255696666783731 1.0 0.5497335107844071 16 P60660,Q9UM22,P09493,P14649,Q14126 5 +Interferon gamma production 0.5965025064651567 1.1341239321598802 0.2567425661537197 1.0 0.5506061693601086 8 Q08722,Q07021 2 +Pancreas development 0.5979116075924769 1.1338510536497508 0.2568570314295915 1.0 0.5506061693601086 9 P04083,P31749 2 +Modulation by host of viral process 0.6028065788444089 1.1334290410903285 0.2570341242220231 1.0 0.5506061693601086 13 P11717 1 +Positive regulation of vesicle fusion 0.5889405538242107 1.1314892983627154 0.257849205173049 1.0 0.5521705018672858 4 P04083 1 +Negative regulation of cell population proliferation 0.3567329108584416 1.1288729990603124 0.258951412523438 1.0 0.5530791232493089 101 P21359,P09493,P10644,P05067,Q13641,Q15392,P15291,Q06481,Q9UHI8,Q96DY7 10 +Central nervous system neuron development 0.602775435465144 1.128215210515014 0.2592290416855669 1.0 0.5530791232493089 14 Q8N3R9,O14949,Q04656,O94813 4 +Regulation of t cell mediated cytotoxicity 0.5900626203276385 1.1275402944218902 0.2595141140096895 1.0 0.5530791232493089 5 O15400,P01889 2 +Positive regulation of t cell mediated cytotoxicity 0.5900626203276385 1.1275402944218902 0.2595141140096895 1.0 0.5530791232493089 5 O15400,P01889 2 +Regulation of myelination 0.6004349110377951 1.1272716841915704 0.2596276304740375 1.0 0.5530791232493089 12 P53634,Q9UPY3,P31749 3 +Synaptic vesicle membrane organization 0.5934662015369225 1.1270159885897006 0.2597357210688047 1.0 0.5530791232493089 7 Q13277 1 +Response to purine containing compound 0.603242370068344 1.1258611616681875 0.2602242909387127 1.0 0.5536144228794182 15 P05067 1 +Polyol biosynthetic process 0.5998778388169892 1.1245462366649046 0.260781367061055 1.0 0.5544388323750207 12 P00374,P04062,Q13510,P61457 4 +Nitrogen compound transport 0.3072950521512602 1.122288228904386 0.2617399094110966 1.0 0.5555679198781346 615 Q99523,Q10713,P07602,P56589,P98164,Q06481,P57737,O00410,P02786,Q07954,Q9H2J7,Q8TEX9,P15311,O95071,Q9Y5K6,Q14108,Q9HAS0,Q9H3S7,P19021,P50897,Q9Y6M1,Q15904,Q99808,Q96MW5,Q8NC96,P10619,P13473,Q7L0J3,P27105,A6NIH7,Q8WUX9,Q8NFH5,P63241,O43772,Q9NQ11,P51991,P43034,P31749,Q96GC9,Q9UBF2,Q99747,Q92688,Q9BRG1,Q9UL25,P50416,O60831,O15173,Q05D32,Q08722,Q15154,Q8N4H5,Q86VS8,Q8TD16,P08195,Q15629,Q15334,P49321,Q13190,Q9H173,O43752,P21359,O60830,Q9Y6B6,Q92544,Q96D46,Q15070,P04083,P04114,P31751,Q9NV96,O43731,Q96BM9,P67809,Q6P4A7,O15260,P60604,O15400,Q9Y496,Q15041,O00560,P40763,Q9UN37,Q6UWE0,Q92572,Q9NVU7,O60645,Q13277,Q9NVZ3,Q16539,P20645,P55786,P84085,Q99595,O60784,P62258,Q9Y282,P40855,Q86Y82,Q14168,Q5JRA6,Q9H4M9,P46934,O75955,P46379,P31946,O95831,Q4J6C6,O15126,P05556,P30825,Q8TAG9,P08183,O15027,Q12907,Q9Y3E7,O43464,P19784,Q92783,Q8NB49,Q8N183,Q13555,Q32P28,P06493,Q9ULC3,P41440,O14828,Q04917,O95486,O75915 129 +Cell proliferation in forebrain 0.5888870438008675 1.1219462176927206 0.2618853079674679 1.0 0.5556953568670847 5 Q96N67,Q15154 2 +Gliogenesis 0.5600116872952396 1.1211442545306485 0.2622264638376574 1.0 0.556237953595031 58 P21359,P04083,Q96G23,Q13144,P31751,Q9UPY3,Q93074,P19022,P04062,P05067,Q96N66,P07686,P31749,P98164,P40763,Q92542,Q07954 17 +Developmental maturation 0.5929326899808725 1.119746237331498 0.2628219154434545 1.0 0.5569565981565394 43 P21359,P51790,P04062,P05067,O75503,O75787,Q8N5W9,P11413,Q9Y2W6,Q15125 10 +Regulation of sodium ion transmembrane transport 0.6016181285789727 1.117808723222548 0.2636486950853789 1.0 0.5583451545236879 15 P54709,P46934,P35754,O43707,Q04917,Q9H4A3,P05026,P27105,P23634,P50570 10 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.574997835150834 1.117103022232471 0.2639502784446397 1.0 0.5587964395230146 52 P05556,Q16539,Q9UIQ6,Q9C0C9,P62942,Q05D32,P98164,Q06481,O00560,P40763,Q92896,P36896,Q92859,Q07954 14 +Membrane protein ectodomain proteolysis 0.5957968162070814 1.1169084679787515 0.2640334635902908 1.0 0.5587964395230146 10 Q8TCT8,Q92542 2 +Myeloid leukocyte activation 0.6033925320581603 1.1150335367911255 0.2648360506076843 1.0 0.559750093399566 18 P53634,P05067 2 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.5833922658413562 1.114851683881021 0.264913984295555 1.0 0.559750093399566 3 P23634 1 +Myeloid cell development 0.6017665063914825 1.1103515736416991 0.2668475572245954 1.0 0.5623753957695423 17 P05067 1 +Appendage morphogenesis 0.5983962028823262 1.1066056105611537 0.2684644805065395 1.0 0.5646861932463884 14 P42892 1 +Small gtpase mediated signal transduction 0.4276686418885562 1.1059298739144836 0.2687568732519476 1.0 0.5651186191441147 89 Q9NUQ9,P05556,Q7L576,Q96N67,Q9UJU6,Q15392,Q02818,Q9Y624,P26358,P21359,Q9Y5K6,Q13464,P61586,O94813,Q15555,Q9H3F6,A0MZ66,Q68EM7,P41440,P06756,P52565,P11234,O75955,P11233,O00560,Q9UL25,P80303 27 +Regulation of anatomical structure size 0.3927770074658993 1.1052318379178665 0.269059144507038 1.0 0.565571530752605 95 Q9NUQ9,Q15375,Q7L576,Q04656,Q9UJU6,Q96ST3,P42892,O15511,P15311,Q9HB40,P61586,P51797,O94813,P51790,A0MZ66,P58546,Q9NQ11,Q93063,P43034,Q9UQB8,Q9UL25 21 +Toll like receptor signaling pathway 0.597911083485738 1.104212586124902 0.2695009312019201 1.0 0.5663173215379276 14 Q06481,Q5KU26 2 +Carbohydrate derivative catabolic process 0.5939895265317209 1.101353552280522 0.2707428122733262 1.0 0.5681536512164491 40 O00462,Q01459,Q99519,P04066,P06280,P06865,P17900,P04062,P16278,Q9BTY2,P07686,P54802,P15586 13 +Cellular amide metabolic process 0.3034924993708502 1.1002504729293814 0.2712230047806752 1.0 0.5684359652941366 474 Q9UIQ6,P17900,P05067,P04062,P98179,O75503,P42892,O14773,O75976,Q9UMR5,Q9NZ08,Q99805,P63220,Q9UJ14,Q5JPH6,O60512,P06280,P62857,P55010,P06865,Q14444,O43293,P19021,P50897,P55786,Q14671,Q9H1I8,Q07021,Q5PRF9,P31751,Q9Y4U1,Q13510,P07686,P67809,Q9NWW5,Q8WUX2,Q8TAD4,Q13084,Q96PZ0,Q7Z739,Q8NCC3,P00374,Q6P179,Q99519,Q96G23,Q16739,Q9BYT8,P31749,Q15056,P40763,Q567V2,Q92542 52 +Neuron apoptotic process 0.5742979455699665 1.0983798382534713 0.2720386625145941 1.0 0.5692685715595294 51 P21359,Q15375,P51858,P31751,Q01105,Q99538,P04062,P05067,O95831,P50897,Q13564,Q92542,Q99720 13 +Cell killing 0.6014143592771147 1.0970611052929962 0.272614681269812 1.0 0.5700217389834135 21 Q9BY67,O15400,P11279,P01889,P53634 5 +Regulation of cellular ketone metabolic process 0.5990769225022184 1.0968985933526991 0.2726857237300981 1.0 0.5700217389834135 17 P04083,Q06481,P31749 3 +Regulation of dendrite morphogenesis 0.5988271884705434 1.0956497378853487 0.2732320863651818 1.0 0.5700229119080142 17 P39880,P46934,P43034,Q9UJU6,Q04917,Q14444,Q9UQB8,P61160 8 +Biological process involved in symbiotic interaction 0.4679711059164479 1.094847371896584 0.2735835087245355 1.0 0.5700229119080142 81 P07858,P08195,P11279,O15118,Q14108,Q8WTV0,Q9BTY2,P27105,P11717,Q9Y624,P02786 11 +Protein localization to organelle 0.3102553499265933 1.0930794102807295 0.2743589352666948 1.0 0.5701458628826649 344 Q96AC1,Q99523,Q10713,P56589,Q96ST3,Q06481,O14773,O00410,Q9P258,P02786,Q8TEX9,P15311,O95071,Q96HY6,Q9Y5K6,Q14108,Q9H3S7,P13473,P11279,P52789,Q8WUX9,Q8NFH5,Q9BUR4,Q9NQ11,Q8NCM8,P31749,Q9P0I2,P11233,Q9BRG1,Q15154,Q8N4H5,Q9H1Z9,Q8TD16,Q86VS8,Q15629,Q15334,P46060,P24390,P21359,O60830,P68036,Q9UNF0,Q9P2S5,Q96D46,Q9H2M9,Q15070,Q96C92,Q96DY7,Q15006,Q9NV96,O43731,O14777,P67809,O95251,P60520,O75381,Q9UI26,Q9UPT5,Q9Y512,Q5JRX3,O15344,O14657,P14923,P15927,P40763,Q9BW27,Q9UN37,Q99797,Q6UWE0,Q96ES7,Q7Z5K2,P35658,O60518,P50748,Q9H4H8,Q16539,P20645,P55786,Q99595,P51858,P62258,P40855,Q5JRA6,Q9H4M9,P46934,P46379,Q9Y6C9,O95831,Q9UH99,Q8NEY8,O15027,O43464,P19784,Q92783,Q15555,P53350,O43292,P06493,Q9ULC3 99 +Negative regulation of steroid metabolic process 0.576276187665985 1.091380702000269 0.2751054003402766 1.0 0.570766018511934 2 P05023 1 +Proteasome assembly 0.5875666670158026 1.0911368327475444 0.2752126777433119 1.0 0.570766018511934 8 Q9BT73,Q8N6M0,O00231 3 +Regulation of cytoskeleton organization 0.3319794156444095 1.089805305594585 0.2757989163484944 1.0 0.5710635083023633 136 Q08722,Q96AC1,Q9NUQ9,Q8TD16,Q7L576,P23396,Q9UJU6,O15511,Q13576,Q9Y624,Q07954,P15311,Q9Y5K6,Q9Y3E7,P61586,O43293,P19021,O94813,Q15555,P53350,Q68EM7,Q8WUX9,Q13136,Q14203,P58546,P52565,P09493,P43034,Q9UQB8,P17655 30 +Cellular response to organic cyclic compound 0.329213357436747 1.0893607442385027 0.2759948353162964 1.0 0.5710635083023633 113 Q13185,Q9P1Z2,O15118,P05067,O15164,Q96ST3,P23634,P08069,P26358,P15311,O95071,Q96HY6,Q5KU26,P61586,P04083,Q9Y297,Q86X55,P61160,Q9NUD5,P41440,P46934,P11234,O75955,Q04917,Q15185,Q9GZZ9,O95831,P29992,O75915,Q92542,O15173 31 +Positive regulation of t cell proliferation 0.5911972873465121 1.0881696877659937 0.2765202037499259 1.0 0.5710635083023633 11 P04083,P02786,P04439 3 +Positive regulation of protein containing complex disassembly 0.5849022655627641 1.0859856263589287 0.2774853515212214 1.0 0.571729039750726 7 P08069,P04062 2 +Negative regulation of organic acid transport 0.5812242076830528 1.0855074583630846 0.2776969621646383 1.0 0.571729039750726 5 P31751,P31749 2 +Regulation of tau protein kinase activity 0.5748008262024278 1.0844415300946546 0.2781690783644071 1.0 0.5719222919730345 2 P07900 1 +Positive regulation of tau protein kinase activity 0.5748008262024278 1.0844415300946546 0.2781690783644071 1.0 0.5719222919730345 2 P07900 1 +Regulation of immune effector process 0.5865985972743956 1.082595184018085 0.2789881458891841 1.0 0.5727571206996495 43 Q08722,P04083,Q9BY67,P11279,Q06481,P01889,O15400,Q07021,P02786 9 +Regulation of lymphocyte mediated immunity 0.5984772968791712 1.0820803461540671 0.2792168280634683 1.0 0.5730458860949492 21 Q9BY67,P11279,P01889,O15400,P02786,P04439 6 +Regulation of activin receptor signaling pathway 0.5782191719881589 1.0806825522586971 0.2798383469042598 1.0 0.5736249975397347 4 P36896 1 +Activin receptor signaling pathway 0.5782191719881589 1.0806825522586971 0.2798383469042598 1.0 0.5736249975397347 4 P36896 1 +Negative regulation of small molecule metabolic process 0.5951334299392953 1.0771844665163255 0.2813978634400993 1.0 0.5749843349011445 17 Q06481,Q92520,P31749 3 +Gtp biosynthetic process 0.5793571546125977 1.0766369568332443 0.2816424869798641 1.0 0.5753036053463808 5 O75414 1 +Protein localization to cell junction 0.5973025215863784 1.0741488566269677 0.2827559702529685 1.0 0.5766733603843437 22 Q9Y496,Q13277,Q9UDY2,Q9UQB8,Q9Y624 5 +Carbohydrate transmembrane transport 0.5948802020074219 1.0722632787408184 0.2836017954046805 1.0 0.5779948268474202 18 Q06481,Q99523,P31751,P31749 4 +Extracellular vesicle biogenesis 0.5889081938555124 1.0709253726719306 0.2842029862885702 1.0 0.5779948268474202 12 Q9Y3E7,Q9UN37,O00560,Q9NQ11 4 +Positive regulation of cell cycle g1 s phase transition 0.5959796738245088 1.0693470531715457 0.2849133157254018 1.0 0.578770287717671 21 Q13619,P04083,Q96HY6,P31749,Q9H4H8,Q9UHI8,Q96DY7 7 +Response to dsrna 0.5942875766092898 1.0692880279471093 0.2849399035537843 1.0 0.578770287717671 18 Q9NUD5,P41440,Q5KU26,P08195,O75955 5 +L alpha amino acid transmembrane transport 0.5870268095257063 1.0678853672620852 0.2855722238699312 1.0 0.5796929146845189 11 P05556,P08195,P30825,Q15041,O75915 5 +Positive regulation of heart growth 0.5751276821439966 1.066051730004176 0.2864002581633627 1.0 0.580649542399094 4 Q16539 1 +Positive regulation of cell projection organization 0.5080672445857213 1.0652490689269054 0.2867632338373673 1.0 0.5810235456835547 71 Q15334,Q9UQ16,Q7L576,Q04656,Q9UJU6,P08069,Q13308,Q14108,Q9P2S5,Q14444,Q96C92,O94813,Q5T0N5,Q15555,P23229,Q9NV96,Q32P28,A0MZ66,Q16181,P61160,P39880,Q9H4M9,P43034,P11233,Q9NUM4,Q9UQB8,Q9UL25 27 +Regulation of sodium ion transport 0.5928383307909533 1.0620136728097147 0.2882294781261962 1.0 0.5832682320800552 18 P54709,P46934,P35754,O43707,Q9H4A3,P31749,Q04917,P05026,P27105,P23634,P50570 11 +Glycolipid biosynthetic process 0.5870130787668485 1.0616730250621291 0.2883841493835404 1.0 0.5833998795795052 12 Q9H490,O60512,Q16739,Q11206,Q99805 5 +Cellular response to oxygen radical 0.5759407663478452 1.060414813628439 0.2889559258091756 1.0 0.5841935021794202 5 P00374 1 +Response to oxygen radical 0.5759407663478452 1.060414813628439 0.2889559258091756 1.0 0.5841935021794202 5 P00374 1 +Regulation of pattern recognition receptor signaling pathway 0.5939586398428922 1.0590480326473803 0.2895779051745453 1.0 0.5848508824619523 21 Q9NUD5,O75955,Q9Y4E8,Q06481,Q14671,Q07021,Q9NPR9 7 +Regulation of bmp signaling pathway 0.5876268215691547 1.0589107302034844 0.2896404370287764 1.0 0.5848508824619523 13 P98164,Q92859 2 +Regulation of platelet activation 0.5732006446861825 1.0569370925778976 0.2905402984679819 1.0 0.5849529382113839 4 Q9Y624 1 +Anatomical structure homeostasis 0.5872101297658068 1.0557975029137423 0.2910607393241005 1.0 0.5854481885605299 39 P21359,Q15555,P05556,Q9UDY2,Q9UBB6,P51790,P13473,P10253,O14773,P78310,P38571,Q9Y624,P02786 13 +Positive regulation of actin filament bundle assembly 0.5869717679357725 1.0556998985565835 0.2911053435284847 1.0 0.5854481885605299 13 Q08722,Q96AC1,P60953,P35080,P09493,P61586,O75116 7 +Positive regulation of catalytic activity 0.3166161729762556 1.05479106614261 0.2915208914122476 1.0 0.5855464361970132 211 Q96AC1,Q15375,P05556,P07602,Q15334,P23396,P05067,Q04656,P0CG13,Q96N67,P23634,Q9BRX5,P08069,Q9Y624,Q9P258,P46060,P21359,Q8IZ81,P68036,Q16539,Q96HY6,Q99538,O43464,Q8WTV0,P61586,Q15555,P23229,P53350,P31751,Q9Y297,Q9Y263,Q8NDZ4,Q9BTE7,P00374,Q9BUR4,Q9BRT9,P26583,P11234,P31749,Q15185,Q9NUM4,P31946,O60934,P40763,Q92688,O95831,O75915,Q9Y3P9,Q92542 49 +Regulation of chemotaxis 0.5941442287425558 1.0544781508566354 0.2916640587401171 1.0 0.5855464361970132 25 Q99538,Q07021,Q13641,O94813 4 +Leukocyte chemotaxis 0.5933963417918938 1.0502844406877554 0.2935873566121216 1.0 0.5879358690120502 26 Q99538,O94813,Q07021,P78310 4 +Multivesicular body sorting pathway 0.5858581293169375 1.0502423923518711 0.2936066835880453 1.0 0.5879358690120502 13 Q99523,Q9Y3E7,Q9H3S7,Q92783,Q9BRG1 5 +Endosome transport via multivesicular body sorting pathway 0.5858581293169375 1.0502423923518711 0.2936066835880453 1.0 0.5879358690120502 13 Q99523,Q9Y3E7,Q9H3S7,Q92783,Q9BRG1 5 +Regulation of peptidyl serine phosphorylation 0.5920291536924943 1.0492196662253923 0.2940770293316377 1.0 0.5886966362081677 21 P05067,P02786 2 +Negative regulation of release of cytochrome c from mitochondria 0.5770844429494216 1.0485893769441683 0.2943671471735476 1.0 0.5887467531758713 7 Q9H3K2,P31749 2 +Gdp metabolic process 0.5732269272566457 1.0475380794360756 0.2948514790006458 1.0 0.589247427354135 5 Q9UDY2 1 +Regulation of cellular protein catabolic process 0.4160689869863848 1.045523165125023 0.2957812398852162 1.0 0.5906130721289927 90 O95816,P04062,P98164,Q9H2J4,Q07954,P15311,Q96HY6,P19784,Q9Y4X5,P53634,P53350,Q96KB5,Q9UNN5,Q9NQ11,Q9GZU8,P31749,Q9GZP4,P46379,O00560 19 +Regulation of cellular response to insulin stimulus 0.5886600120260863 1.0448563540460671 0.2960893645935294 1.0 0.5907664624257176 17 Q06481 1 +Eye morphogenesis 0.5866393382088466 1.0436518980730505 0.2966464722956043 1.0 0.5913329407905977 15 P21359,P54802,P40763,Q16706 4 +Negative regulation of peptidase activity 0.582532892441009 1.0427578868469678 0.2970604403297778 1.0 0.5917574867034436 41 P07858,P05067,Q15392,Q06481,Q07954 5 +Regulation of cell migration involved in sprouting angiogenesis 0.5697875734624052 1.0408046535830566 0.2979662198451791 1.0 0.5930174537426218 4 P04083 1 +Extracellular exosome assembly 0.5693784764087529 1.0388719875981665 0.2988642758760789 1.0 0.5944413186536124 4 O00560 1 +Protein localization to synapse 0.5819233926172459 1.036844554348033 0.2998083074650233 1.0 0.5955911143110473 12 Q13277,Q9UQB8 2 +Regulation of protein localization 0.3133611821214412 1.034551217968608 0.3008785457277145 1.0 0.5971035828573258 228 Q96AC1,P05556,Q13277,Q10713,Q96ST3,P23634,O00410,O43752,P02786,Q07954,P21359,Q9Y6B6,P15311,O95071,Q96HY6,Q9Y5K6,Q16539,O43464,Q92544,P19784,P19021,Q96D46,P55786,Q8N183,P53350,P31751,P62258,Q9NV96,Q9Y282,Q32P28,P62942,O14777,O95251,P06493,O00264,P27105,P60604,O15400,O96028,Q9ULC3,Q9NQ11,O95486,P19022,P31749,Q9UN37,Q05D32 46 +Receptor catabolic process 0.5779592325139814 1.030536936958493 0.3027580222852712 1.0 0.5985770159901942 10 Q99538,P07384 2 +Regulation of polysaccharide metabolic process 0.5748894361313097 1.030280229298558 0.3028784772144064 1.0 0.5985849686295646 8 P31749 1 +Nucleotide excision repair dna gap filling 0.5627028622012482 1.027631074442352 0.30412340119056 1.0 0.6001343867082588 2 P28340 1 +Regulation of skeletal muscle tissue development 0.5707621890177902 1.0266447929706028 0.3045877538309096 1.0 0.6006865426959169 6 P41440,O75955 2 +Receptor internalization 0.5885188891663429 1.0261022548711085 0.304843387555116 1.0 0.6010086168939446 24 P41440,P05556,Q9UQ16,P46934,O75955,O00560,P02786,Q07954 8 +Regulation of organ growth 0.578300513053152 1.025505659886691 0.3051246561970475 1.0 0.6011363253681815 11 P11413,Q16539,P31749,P06493 4 +Erythrocyte maturation 0.5665206427836191 1.0253773204852834 0.3051851851523564 1.0 0.6011363253681815 4 P11413 1 +Response to hydroperoxide 0.5621127176158144 1.024864656374513 0.3054270533653327 1.0 0.6012802139004284 2 Q05655 1 +Polysaccharide biosynthetic process 0.5851881295750601 1.023654680722922 0.3059984080790963 1.0 0.6020095607721114 18 Q7LGA3,O43505,Q93063,P31749 4 +Chemokine c c motif ligand 5 production 0.5615225730304012 1.0220987489700564 0.3067341652314836 1.0 0.6025086169105893 2 Q7Z434 1 +Positive regulation of chemokine c c motif ligand 5 production 0.5615225730304012 1.0220987489700564 0.3067341652314836 1.0 0.6025086169105893 2 Q7Z434 1 +Regulation of potassium ion transport 0.5798375037106637 1.0207648264976528 0.3073658726301955 1.0 0.6025148542073391 13 P05556,P62258,P54709,P46934,Q9H4A3,P05026,P50570,P33176 8 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.585841279389234 1.020116274176211 0.3076733193707839 1.0 0.6027263379522833 33 P04083,Q9BY67,O15400,P01889,P40763,P53634,O96028,Q07021,P02786,P04439 10 +Regulation of postsynaptic membrane neurotransmitter receptor levels 0.5784805286012972 1.0200685776792804 0.3076959379650748 1.0 0.6027263379522833 12 Q13277,Q15334,Q9UQ16,Q14254,Q9NQX3 5 +Regulation of dendritic spine development 0.581271457862029 1.0171375496073505 0.3090879995450797 1.0 0.6046037926488537 15 Q14444,P61160,Q9UQB8,Q9UQ16 4 +Negative regulation of proteolysis 0.5128494875838833 1.0166436212873788 0.3093229949174017 1.0 0.6046037926488537 68 P07858,Q9GZU8,P05067,Q15041,Q15392,P31749,Q06481,O00560,Q92896,Q07954 10 +Alpha beta t cell activation 0.5817693601272796 1.0148551528819136 0.3101748787203959 1.0 0.6060139437184207 16 P04083,P40763,P04439 3 +Ribonucleoprotein complex disassembly 0.5662086025890354 1.0142820666546173 0.3104481787237276 1.0 0.6063659296404041 5 Q9UBB9,P33176 2 +Positive regulation of dna ligation 0.5591619946887079 1.011040397504376 0.3119970952016953 1.0 0.6086087570008918 2 P18887 1 +Positive regulation of leukocyte mediated immunity 0.5855181159601655 1.010595263545383 0.3122101837017417 1.0 0.6086087570008918 24 Q9BY67,P11279,P01889,O15400,P02786,P04439 6 +Chemical synaptic transmission postsynaptic 0.5788076657648087 1.0101664054898676 0.3124155715066623 1.0 0.6086087570008918 14 P05067,P31749 2 +Regulation of postsynaptic membrane potential 0.5788076657648087 1.0101664054898676 0.3124155715066623 1.0 0.6086087570008918 14 P05067,P31749 2 +Histone deubiquitination 0.568635897521 1.0082617222815335 0.3133288337899578 1.0 0.6094325389819616 7 Q96ES7 1 +Glandular epithelial cell differentiation 0.5648266114343602 1.0077420644225328 0.3135783054621899 1.0 0.6096990604037532 5 P31749 1 +Response to estradiol 0.5823497325755699 1.0058882958282576 0.3144693070146753 1.0 0.6100104852996235 19 P04083,P04114,P19021,P40763,P08069 5 +Bleb assembly 0.5602158708315275 1.0056392196570445 0.3145891505521159 1.0 0.6100154607595494 3 Q9NR77 1 +Triglyceride metabolic process 0.5751293727020411 1.0037560824286675 0.3154961976421946 1.0 0.6114558638436103 12 P04114,Q96N66,Q8WTV0 3 +Cellular response to muramyl dipeptide 0.5596221959858205 1.0028510451953927 0.3159327357661614 1.0 0.6119375512757248 3 Q92974,Q9NZZ3 2 +Cell activation involved in immune response 0.5788038575747385 1.0022647891980214 0.3162157236288019 1.0 0.6123034981628496 38 P04083,P11279,Q04656,P05067,P40763,O96028,P02786,Q07954 8 +Integrin mediated signaling pathway 0.5812755753668044 1.0004872497875776 0.3170747649415075 1.0 0.6134195303920399 19 Q08722,Q96AC1,P05556,P23229,P06756,Q9UHI8 6 +Membrane raft assembly 0.5646987166646809 0.9978426213553796 0.3183556790095787 1.0 0.6139298155562423 6 Q14254,P41440,Q9UNF0,O75955 4 +Adaptive immune response 0.5734714016650377 0.997808365863004 0.3183722927103511 1.0 0.6139298155562423 42 P04083,P10321,Q9BY67,O15400,Q6P179,O96028,P01889,O60934,P40763,P53634,Q9NZ08,Q07021,P02786,P04439 14 +Sprouting angiogenesis 0.5773057446502774 0.9975760456746108 0.3184849815423494 1.0 0.6139298155562423 15 P04083,P31749,Q5JRA6,O94813,Q9Y6I3 5 +Forebrain generation of neurons 0.5646329570344426 0.9975305782630982 0.3185070389431124 1.0 0.6139298155562423 6 O14949,Q04656,P61586 3 +Lipid import into cell 0.5662104251643113 0.9967039638794865 0.3189082250890447 1.0 0.6139298155562423 7 P31749 1 +Ameboidal type cell migration 0.4658930226279907 0.9966971137396876 0.3189115510935187 1.0 0.6139298155562423 79 P21359,P04083,Q5JRA6,Q16539,Q99538,P19022,Q13641,P31749,Q8WTV0,Q06481,Q13685,P42785,P36896,Q07021,O94813,Q7Z739 16 +Positive regulation of reactive oxygen species biosynthetic process 0.5589905094516244 0.9898793975993244 0.3222330706667979 1.0 0.6186190769804939 4 P51790 1 +Positive regulation of protein targeting to membrane 0.56937201647644 0.989099179427714 0.3226146190661279 1.0 0.6191689770402395 10 P27105 1 +Response to ether 0.5563754427390709 0.987613361139118 0.3233420401535647 1.0 0.6196450003798061 3 Q6PKG0,P11802 2 +Regulation of transport 0.3106066617806489 0.987307967316918 0.323491686007612 1.0 0.6196450003798061 333 Q08722,P05556,Q9UQ16,P54709,Q04656,P05067,Q7L576,Q06481,Q9H223,P08183,P23634,O00410,Q08431,P07384,Q07954,P21359,Q12907,Q9Y6B6,P15311,Q16539,O95071,Q9Y5K6,Q9Y3E7,O43464,Q8WTV0,Q9H3S7,Q92544,P19784,Q92783,P19021,P50897,P55786,P11413,Q8N183,P04083,Q13555,P31751,P62258,Q9NV96,P11279,Q9Y282,Q7L0J3,P62942,Q32P28,P06493,Q8TAD4,P27105,O15260,P60604,Q9P2B4,Q9ULC3,P41440,Q9NQ11,Q9H4M9,P06756,P46934,P19022,O95486,Q15041,O75955,P31749,Q04917,Q96GC9,O00560,O75844,Q9UN37,O75915,Q6UWE0,Q4J6C6,Q05D32 70 +Cell adhesion mediated by integrin 0.5629798274178358 0.9813252411340035 0.3264323792779027 1.0 0.6228237951638764 7 P06756,P23229 2 +Golgi disassembly 0.5588349971322626 0.9794248041015632 0.3273701262919584 1.0 0.6240642817454316 5 Q13190 1 +Inositol phosphate metabolic process 0.5651352290178229 0.9759749544749744 0.3290768758905065 1.0 0.6253146106816279 9 Q13572,Q9NX62 2 +Iron ion transport 0.5633058086056303 0.974866970229952 0.3296262519878545 1.0 0.6257512299697726 8 P02786 1 +Positive regulation of sodium ion transport 0.5676611620913988 0.9739842060558302 0.3300643813104047 1.0 0.6259012881825619 11 P54709,P35754,O43707,P31749,Q9H4A3,P05026,P50570 7 +Supramolecular fiber organization 0.3177807223101593 0.9707822250132764 0.3316567358433684 1.0 0.6280299518285837 183 Q08722,Q96AC1,Q9NUQ9,P05556,Q86VS8,Q7L576,P05067,P23396,Q14019,Q04656,Q9UJU6,P57737,O15511,Q13576,Q9NVX0,Q9Y624,P21359,P13674,P15311,Q9Y5K6,Q99471,P67936,P61586,P12814,O43293,Q92791,O94813,Q96S59,P62942,A0MZ66,Q68EM7,Q16527,P23258,Q13136,P61160,Q14203,P58546,P09493,P10644,P43034,Q9UQB8,Q8N5W9,Q15154 43 +Regulation of neurogenesis 0.5231100733028604 0.9707570519968002 0.331669274099335 1.0 0.6280299518285837 63 Q15375,Q96N67,Q7L576,Q9UJU6,Q9UBS4,Q16706,P98164,Q06481,P21359,Q14444,O94813,Q9UPY3,A0MZ66,P55209,P61160,P39880,Q96G23,P26583,P43034,Q04917,Q9UQB8,Q9UL25,Q15154 23 +Dendrite morphogenesis 0.576509198588214 0.9692764795566694 0.3324072612805815 1.0 0.6292386322035016 33 P39880,P05556,Q9UQ16,P46934,Q9UJU6,Q13641,P43034,Q04917,Q14444,Q9NUM4,Q9UQB8,Q9UL25,P61160 13 +L amino acid transport 0.5677753908634371 0.9680246379468777 0.3330320651082561 1.0 0.6296946685607747 12 P05556,P08195,P30825,Q15041,O75915 5 +Xenobiotic transport 0.558320760819655 0.9676137978259436 0.3332372837110977 1.0 0.629716898972205 6 P35670,P08183,Q9NV96 3 +Regulation of endothelial cell migration 0.5771261687610388 0.966666296383453 0.3337108809099436 1.0 0.6300631771240525 30 P21359,P04083,Q99538,Q8WTV0,P31749,Q13685,P42785,O94813 8 +Negative regulation of histone h4 acetylation 0.5494246090292174 0.9655246965979598 0.3342820722602149 1.0 0.6302277122542713 2 Q13363 1 +Negative regulation of cellular response to growth factor stimulus 0.5694026153533364 0.9640539316506044 0.3350188876319619 1.0 0.631251218085115 14 P98164,O94813 2 +Negative regulation of neuron apoptotic process 0.576181251211967 0.9611960898736942 0.3364535820583074 1.0 0.632124911745911 25 Q99538,P04062,P50897,Q01105 4 +Regulation of receptor mediated endocytosis 0.5728150187732853 0.949051610038968 0.3425943638133983 1.0 0.6382097282351452 22 P41440,Q9Y5K6,P06756,P05067,O75955,O00560,P50897,Q9UL25 8 +Imp salvage 0.54558866922397 0.9476446622623996 0.3433103812252858 1.0 0.6392879238491449 2 P07741 1 +Regulation of keratinocyte migration 0.5476500685611583 0.9467618983028918 0.3437601211475987 1.0 0.6395765614949608 3 Q15555 1 +Keratinocyte migration 0.5476500685611583 0.9467618983028918 0.3437601211475987 1.0 0.6395765614949608 3 Q15555 1 +Regulation of t circle formation 0.5452935969312548 0.9462705859226704 0.3440105919322982 1.0 0.6398597009940747 2 Q15554 1 +Positive regulation of exocytosis 0.569514842473759 0.9453465359840332 0.3444819876201586 1.0 0.6403178577716323 18 P11279,Q9UN37,O00560,Q9NQ11 4 +Regulation of vesicle fusion 0.5511787592398317 0.9433393109560484 0.3455073745518913 1.0 0.6415439270772425 5 P04083 1 +Regulation of response to wounding 0.5697384465100362 0.9426059638236156 0.3458824882274638 1.0 0.6420294688007969 19 Q96G23,P04083,P05556,Q04656,P08069,Q11206,P10586 7 +Blood vessel endothelial cell migration 0.5716844897442859 0.9410944404588536 0.346656464337143 1.0 0.6420294688007969 23 P21359,P04083,Q16539,Q8WTV0,P31749,Q5JRA6,P42785,O94813 8 +Mammary gland development 0.5719953241857091 0.9409005631476908 0.3467558190137862 1.0 0.6420308253070958 24 P31751,Q9Y297,P35670,Q04656,P31749,Q9UNS2,P00403,P19021,Q99808,P07384 10 +Regulation of glucose transmembrane transport 0.5655744383368553 0.9398730532760546 0.3472826809436218 1.0 0.6426407768456447 15 Q06481,P31751,P31749 3 +Ventricular cardiac muscle cell action potential 0.5500033688689654 0.937810482689896 0.3483418129978188 1.0 0.64410015207131 5 Q14126,P15924 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.5650954675461692 0.9375230851849006 0.3484895546921551 1.0 0.6441416811601164 15 P21359,Q9UNN5,Q99523 3 +Regulation of bicellular tight junction assembly 0.5509715067630988 0.9328820299702438 0.3508808815446442 1.0 0.647927662158287 6 Q9Y624,Q13464 2 +Lymphocyte mediated immunity 0.5684801201955794 0.9314959189985929 0.3515970946368267 1.0 0.6480899508922144 35 Q9BY67,O15400,P11279,P01889,P53634,O96028,Q07021,P02786,P04439 9 +Cellular monovalent inorganic anion homeostasis 0.5420478017114232 0.931168790525506 0.3517662591423689 1.0 0.6480899508922144 2 P12277 1 +Monovalent inorganic anion homeostasis 0.5420478017114232 0.931168790525506 0.3517662591423689 1.0 0.6480899508922144 2 P12277 1 +Organic acid transmembrane transport 0.5694871412562172 0.9311264168103844 0.3517881751861438 1.0 0.6480899508922144 33 Q9H2J7,P41440,P05556,P31751,P08195,P30825,Q9UBX3,Q15041,P31749,P98164,P08183,O75915,P50416,O43772 14 +Regulation of receptor signaling pathway via stat 0.5523617924191829 0.9309236053101938 0.3518930829829454 1.0 0.6480899508922144 7 Q6IA86 1 +Protein kinase b signaling 0.5705070803196187 0.9308719378559488 0.3519198120436217 1.0 0.6480899508922144 26 P05556,Q99829,Q13641,P31749,P98164,P08069,Q07021 7 +Positive regulation of extrinsic apoptotic signaling pathway 0.557032260060329 0.9297876986101018 0.3524810167416381 1.0 0.6489398809355386 10 P21359,Q9UNN5,O43464 3 +Positive regulation of leukocyte cell cell adhesion 0.569915453026621 0.927798592363597 0.3535120543548726 1.0 0.6502303954185639 26 Q08722,P04083,P31749,Q11206,P02786 5 +Carboxylic acid transport 0.5663756914007875 0.9276647375585396 0.3535815053428135 1.0 0.6502303954185639 37 P21359,Q9H2J7,P05556,P04083,P08195,P07602,Q9UBX3,Q7L0J3,Q15041,P98164 10 +Regulation of bone mineralization 0.5496165423325464 0.9264917996696944 0.354190456752695 1.0 0.6509824600395383 6 O75844,Q8N5W9,Q6W2J9 3 +Regulation of actomyosin structure organization 0.5685137873418132 0.9248962317659962 0.3550198869295689 1.0 0.6521386749185929 23 Q08722,Q96AC1,P60953,P35080,P09493,Q13464,P61586,Q13136,Q9Y624,O75116,Q13177 11 +Regulation of respiratory gaseous exchange 0.544991277867761 0.9241681148986955 0.3553987937588021 1.0 0.6524664826197974 4 Q9C0B1 1 +Regulation of respiratory system process 0.544991277867761 0.9241681148986955 0.3553987937588021 1.0 0.6524664826197974 4 Q9C0B1 1 +Rescue of stalled ribosome 0.5469956861539527 0.9236774669952876 0.3556542672760616 1.0 0.6527514180905445 5 Q9H1I8 1 +Corticosteroid receptor signaling pathway 0.5487997850763495 0.9226419637797336 0.3561938194547862 1.0 0.6531892294790587 6 P46934,Q04917 2 +Regulation of gliogenesis 0.5595699284476665 0.921977234023888 0.3565404507698071 1.0 0.6536407588035608 13 Q96G23,P98164,P21359 3 +Cellular anion homeostasis 0.5422077922077893 0.9213648366138176 0.3568599808224766 1.0 0.6540423635006539 3 P12277,P22413 2 +Regulation of protein targeting to membrane 0.5566889574902487 0.9210765730879908 0.3570104502516742 1.0 0.6540583331456719 11 P27105 1 +Regulation of protein exit from endoplasmic reticulum 0.551945775302042 0.9207707990584362 0.3571701035841572 1.0 0.6540583331456719 8 Q92544,Q9Y6B6,Q9NV96 3 +Positive regulation of immune effector process 0.5656027169497728 0.919258178557392 0.3579605470678781 1.0 0.6551745717664162 36 P04083,Q9BY67,P11279,Q06481,P01889,O15400,P02786 7 +Regulation of animal organ morphogenesis 0.5547402047042916 0.9188074566797308 0.3581962915359824 1.0 0.6551745717664162 10 Q8TAA9,P60953,Q13308,Q93074,P61586 5 +Mesoderm development 0.5576006244175018 0.9187656495921172 0.3582181631617018 1.0 0.6551745717664162 12 Q93063,Q96PZ0,P10644 3 +Neural precursor cell proliferation 0.5681719921037123 0.9179607207158148 0.3586394302701212 1.0 0.6551745717664162 28 P21359,P19022,Q96N67,P43034,P61586,P98164,Q06481,P55209,Q15154 9 +Positive regulation of nervous system development 0.5570708975043391 0.9177748178647416 0.3587367685426414 1.0 0.6551745717664162 44 P39880,Q9UPY3,Q9UJU6,Q13641,Q16706,P98164,Q14444,A0MZ66,Q9UQB8,P55209,P61160,O94813 12 +Positive regulation of cell cell adhesion 0.5664522198516493 0.917259199080848 0.3590068321777246 1.0 0.6551745717664162 34 Q9NUQ9,Q08722,P04083,P41440,P30825,Q14254,O75955,Q9H3S7,P31749,P61586,Q11206,Q9Y624,P02786,P04439 14 +Negative regulation of gene expression 0.3031557585800259 0.9163925926147442 0.3594610190614298 1.0 0.6553041820470199 278 Q10713,Q969Z0,P04062,P05067,Q8NEY8,Q96ST3,Q06481,P23634,Q9UK45,Q9UQR1,Q07954,P49591,P15311,Q5KU26,Q96HY6,Q9Y5K6,Q99538,Q16539,Q9C0B1,Q9H074,Q14444,P16989,O43293,Q9NRF9,Q92896,Q14671,Q8ND04,P36896,Q07021,Q15631,Q5PRF9,P04083,Q9UPY3,P67809,P06493,Q9Y2B0,Q6GMV2,Q96PZ0,Q7Z739,P00374,P34896,Q99829,P26583,P10644,P31749,P40763,P26368,O75844,Q9Y2W6 49 +Cell cycle dna replication initiation 0.5474122282183286 0.9161053816458992 0.3596116254254731 1.0 0.6553952075923376 6 P33993,Q9BRX5 2 +Sulfur compound metabolic process 0.3141747955372175 0.9136006663922456 0.3609267161217928 1.0 0.6566889105513894 106 Q9UJ14,Q9UBX3,Q93063,Q9P2E5,Q9Y697,P16278,Q9NX62,Q9NRB3,Q8WUX2,P50897,P15586,Q9UMR5,O43505,Q11206,Q8NCH0 15 +Cell cell signaling by wnt 0.4880792701853179 0.9123544147293404 0.3615821781000914 1.0 0.6569955418048838 71 Q96AC1,Q8TAA9,Q9BZK7,O95071,Q16539,Q9P1Z2,Q93074,Q9NWU2,P05067,Q13641,Q99471,Q9H3S7,P61586,P19784,P19022,O75787,O43293,Q07954 18 +Organ growth 0.565584410693768 0.9123221650033416 0.3615991496365835 1.0 0.6569955418048838 22 Q16539,P07602,P10644,P31749,P06493,O75844,Q8NDZ4,P11413 8 +Anion homeostasis 0.5423678771774384 0.9119032664122678 0.3618196419220219 1.0 0.6572114589599225 4 P12277,O94925,P22413 3 +T cell proliferation 0.5661551699052146 0.908284457906663 0.3637279517896175 1.0 0.6601468986541509 26 P04083,Q9BY67,Q92542,P02786,P04439 5 +Dendritic spine morphogenesis 0.5599484944997604 0.9070975266434732 0.364355225919112 1.0 0.6602684403557519 16 Q15334,Q9UQ16,Q9UJU6,P43034,Q14444,Q9UQB8,P61160 7 +Protein o linked glycosylation 0.5617326710921118 0.9066497337322807 0.3645920528509692 1.0 0.6604046366332246 18 Q86SF2,Q10472,O43505,Q11206 4 +Metal ion homeostasis 0.3968617902556561 0.9061882431397368 0.3648362247847254 1.0 0.6606630941164291 91 Q9NQ11,P61421,P62258,P35670,Q9Y487,Q9NWR8,Q7L0J3,P05067,Q93063,P07686,Q04656,P62942,Q8TAD4,Q15904,Q92859,P02786 16 +Fibroblast migration 0.5603514942434524 0.90425050402298 0.3658625856974495 1.0 0.6616015091362212 17 Q06481 1 +Cell chemotaxis 0.5632998070760821 0.9030450625159177 0.3665019792499264 1.0 0.6623897515038926 35 Q99538,Q13641,P78310,Q07021,O94813 5 +Synaptic vesicle uncoating 0.5358512835644802 0.902409242001174 0.366839513437776 1.0 0.6628157736552656 2 O14976 1 +Regulation of jnk cascade 0.5537932830827526 0.9003958096066922 0.3679096500160246 1.0 0.6639507572529698 12 O00560,P05067 2 +Positive regulation of neuron differentiation 0.5508526139471274 0.9002136850923421 0.3680065447261154 1.0 0.6639507572529698 10 O60271,P46821,Q99829,P61586,Q96ST3,Q8WUJ1,Q13049 7 +Regulation of mitotic cell cycle 0.31914206319126 0.9000765180038335 0.3680795314713203 1.0 0.6639507572529698 143 O75414,P05067,Q96ST3,Q06481,O60921,Q13564,Q9P258,Q13619,Q99538,Q9UJX4,O43293,Q96DY7,P04083,P53350,P62258,O14777,P06493,Q5VTR2,Q9UHI8,Q7L5Y9,Q9UJX5,Q9NXR7,P31749,O00560,O60934,Q9UN37,O75844 27 +Regulation of myeloid cell apoptotic process 0.5418805635987423 0.8996931080688874 0.3682835920799499 1.0 0.6639507572529698 5 P04083 1 +Myeloid cell apoptotic process 0.5418805635987423 0.8996931080688874 0.3682835920799499 1.0 0.6639507572529698 5 P04083 1 +Fatty acid derivative biosynthetic process 0.5572653745298621 0.8991837568863909 0.368554790742104 1.0 0.6642557275003038 15 Q9UMR5,P19021 2 +Neuronal stem cell population maintenance 0.5454485940543407 0.8982469170661398 0.3690539256071745 1.0 0.6645608838732986 7 P19022,Q86VS8,Q15154 3 +Formation of primary germ layer 0.5567806456944835 0.8968154359936003 0.3698174098044209 1.0 0.6650453416771186 15 P06756,Q93063,P10644 3 +Protein neddylation 0.5451074460395914 0.8966376202700512 0.3699123167761668 1.0 0.6650453416771186 7 Q9BTE7 1 +Negative regulation of cell matrix adhesion 0.5429521261649506 0.8951279865726082 0.3707186748835387 1.0 0.6663110363036546 6 P21359 1 +Regulation of defense response 0.401016502498668 0.8943775383383611 0.3711199262433551 1.0 0.6664508889892258 90 Q08722,P04083,Q9BY67,Q8IZ81,Q9NUD5,P28070,P11279,P04062,P05067,Q9NZ08,Q06481,P01889,P53634,Q6UWE0,Q07021,P04439 16 +Regulation of muscle organ development 0.5480135936916183 0.8942166620149524 0.3712059790284074 1.0 0.6664508889892258 9 O75955,P41440,P58546,P16989 4 +Microvillus assembly 0.5384612283768861 0.8936721795028514 0.3714973147124278 1.0 0.6667900520479474 4 P15311 1 +Negative regulation of signaling 0.3077678663362099 0.89152176908983 0.3726493182610013 1.0 0.6679772775087801 211 Q08722,P05556,Q10713,O60313,P04062,Q13641,P98164,P23634,P08069,Q07954,P21359,P15311,Q16539,Q96HY6,Q9Y5K6,Q99538,Q99471,Q8TBX8,O43464,P61586,P19784,P16989,Q92896,Q07021,Q8N183,O94813,Q9NPR9,P23229,Q9H3F6,Q96KB5,Q9Y297,Q96S59,Q9H3K2,P62942,P13693,Q7Z739,Q99829,P06756,P46934,P19022,P26583,P31749,P31946,Q9BRG1,Q05D32 45 +N acetylneuraminate catabolic process 0.5334907052227899 0.8914798286772556 0.3726718082813962 1.0 0.6679772775087801 2 P46926 1 +Morphogenesis of an epithelial sheet 0.5451944960802042 0.8887668780260702 0.3741283801438353 1.0 0.6700345955258233 8 Q96AC1,P61586 2 +Response to peptide hormone 0.4105414493427105 0.8862050632239656 0.3755070357551888 1.0 0.6721338473374427 88 P04083,Q99523,P31751,Q8TBX8,P31749,Q06481,Q9UQB8,P40763,P08069,Q92572 10 +Inflammatory response to antigenic stimulus 0.5456571051390235 0.8830212236822174 0.3772248045222699 1.0 0.6734377782165595 9 Q8ND90,Q16539,P28070 3 +Protein maturation 0.4689033782845105 0.8819723201445953 0.377791776005681 1.0 0.6734377782165595 75 Q10713,O95816,Q15392,O75503,P42892,O75787,O75976,Q99538,O43464,Q9BU23,Q92896,P62942,Q8TAD4,Q86UY6,Q99829,P35670,Q96T76,Q10471,P17655,O75844,Q9H9S5,Q92542 22 +Regulation of alpha beta t cell activation 0.5484782866468597 0.8816735953576458 0.3779533439055056 1.0 0.6734377782165595 11 P04083,P04439 2 +Regulation of actin filament based movement 0.5400473862810059 0.881495138561167 0.3780498841231248 1.0 0.6734377782165595 6 P14923,Q14126,P15924 3 +Morphogenesis of a polarized epithelium 0.552354248805879 0.8809432150401159 0.3783485556847661 1.0 0.6734377782165595 14 P15311,P60953,Q13308,Q8TAA9,Q93074,P43034,P61586 7 +Regulation of potassium ion import 0.5357238272200044 0.8809227352545117 0.3783596410470575 1.0 0.6734377782165595 4 P54709,P05026 2 +Inositol lipid mediated signaling 0.5556021891764132 0.8808335932738126 0.3784078944264477 1.0 0.6734377782165595 17 P21359,Q10713,P46934,P31749,Q8NDZ4,P08069,Q07021 7 +Positive regulation of nitric oxide synthase activity 0.5395814045799263 0.8793103924249143 0.3792330025945643 1.0 0.6741689915048098 6 Q8WTV0,P31749 2 +Microtubule nucleation 0.549270921667484 0.8786265703939682 0.3796037843177893 1.0 0.6746439082470129 12 Q96S59,P23258,Q9NVX0 3 +Regulation of myoblast differentiation 0.5329080905108512 0.8781413353335438 0.379867023457364 1.0 0.6749274898218994 3 Q16539 1 +Positive regulation of endothelial cell migration 0.5573885842136979 0.8772103534875355 0.3803723935273546 1.0 0.6752191594134305 20 P04083,Q99538,Q8WTV0,P31749,Q13685 5 +Membrane raft organization 0.5460099156789459 0.8771087127993304 0.380427592710407 1.0 0.6752191594134305 10 P41440,Q14254,O15118,O75955,P50897 5 +Purine nucleoside biosynthetic process 0.5390006130506636 0.8765882560444911 0.3807103202886994 1.0 0.6752191594134305 6 Q13126 1 +Positive regulation of isotype switching 0.543601942535149 0.8732703785409455 0.3825157220636044 1.0 0.6764898834525884 9 P02786 1 +Positive regulation of b cell mediated immunity 0.543601942535149 0.8732703785409455 0.3825157220636044 1.0 0.6764898834525884 9 P02786 1 +Export from cell 0.3175005477602961 0.8724986767275641 0.382936389744515 1.0 0.6766152014224925 149 O15126,O60645,Q13277,Q15334,P54709,Q8TAG9,Q5SQN1,P08183,P21359,P15311,Q9Y5K6,Q9Y3E7,Q9H3S7,Q92783,P19021,P50897,P20645,Q8N183,P04083,Q13555,P62258,P11279,Q7L0J3,Q32P28,P56545,Q68EM7,Q5JRA6,Q9UN37,Q9NQ11,P35670,O95486,P11234,P43034,P11233,Q9UBF2,O00560,Q9UL25,Q9BRK5,P50416,Q4J6C6 40 +Positive regulation of cilium assembly 0.5417279634488256 0.8723828710603512 0.3829995418190299 1.0 0.6766152014224925 8 Q16181,Q9P2S5 2 +Pons development 0.5316026853913097 0.8720936217623658 0.3831573054342159 1.0 0.676710270856415 3 O14949 1 +Mitochondrial fusion 0.5513873591661287 0.870508759320309 0.3840224344396397 1.0 0.6774150651374028 15 Q9Y6C9,Q99536,P02786 3 +Fatty acyl coa biosynthetic process 0.5461409816213639 0.8704911170258358 0.3840320715633178 1.0 0.6774150651374028 11 Q9UMR5 1 +Formation of translation preinitiation complex 0.5429984621138412 0.8704095086861977 0.3840766521385796 1.0 0.6774150651374028 9 Q15056,P55010 2 +Regulation of notch signaling pathway 0.5411082124861909 0.8694574612909834 0.384596965538643 1.0 0.6779654063516289 8 P31749 1 +Positive regulation of t cell mediated immunity 0.5369546509526735 0.8670070024938478 0.3859381729381534 1.0 0.6799614359478698 6 O15400,P01889 2 +Regulation of biomineralization 0.5416047019927658 0.8638064614848825 0.3876942177165725 1.0 0.6823166686496045 9 P20020,Q13464,Q8N5W9,Q6W2J9,O75844 5 +Meiotic spindle organization 0.5390151764749137 0.85958643001515 0.3900170579124544 1.0 0.6843695544501559 8 O14777 1 +Positive regulation of protein localization to nucleus 0.5532355138309261 0.8587834472072431 0.3904600015641333 1.0 0.6848289144836784 38 Q96AC1,P53350,Q16539,O95071,P31749,P06493,O95251,Q96D46,O00410,P02786 10 +Positive regulation of axonogenesis 0.5497211966159832 0.8569820386194223 0.3914548111998852 1.0 0.6850364074691817 16 Q7L576,Q9UJU6,O94813,A0MZ66 4 +Myeloid leukocyte differentiation 0.5559901898237749 0.8557222451865966 0.3921514326698616 1.0 0.6858962457498118 26 P21359,P04062,P05067,Q15904,P02786 5 +External encapsulating structure organization 0.5558819291116704 0.8551640870314348 0.3924603147211738 1.0 0.686252121631706 26 P21359,P13674,P05556,Q04656,P05067,O75955,P15291,Q9UHI8,Q07954 9 +Response to iron ion 0.5375902985022399 0.852874420823821 0.3937289480363812 1.0 0.6880265265653566 8 Q04656,P02786 2 +Regulation of membrane lipid distribution 0.5356457664284734 0.8521384327311188 0.3941372630536124 1.0 0.6882253358319171 7 Q96GC9,P08183,Q9NV96 3 +Crd mediated mrna stabilization 0.5388572030854537 0.8508078078295445 0.3948761237139033 1.0 0.6882988197023154 9 P67809 1 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5388572030854535 0.8508078078295425 0.3948761237139044 1.0 0.6882988197023154 9 P67809 1 +Amyloid precursor protein metabolic process 0.5534105487131903 0.8507898700791197 0.3948860897883466 1.0 0.6882988197023154 22 Q15392,Q9Y287 2 +Muscle cell differentiation 0.4998114679262455 0.8499236915108509 0.3953675128346039 1.0 0.6889300076427386 65 P05556,Q99523,Q16539,P78310,P11413,Q7Z4V5,Q8IV08,P67809,P06493,Q16527,P41440,P58546,Q9H4M9,Q9BYT8,P09493,P19022,O75955,P10644,P31749,P17655 20 +Cellular carbohydrate metabolic process 0.4868054600363777 0.8494675048238829 0.3956212044627802 1.0 0.6891875946086966 69 Q7LGA3,P31751,Q9BYT8,P08236,Q14108,Q93063,P16278,Q9NX62,P15291,P31749,Q92520,Q13572,O43505,P10253 14 +Response to isoquinoline alkaloid 0.5265643447461512 0.8488017253395889 0.3959916299668893 1.0 0.689279548418302 3 P63151,P06744 2 +Regulation of t cell mediated immunity 0.5339194273655694 0.8440493753608056 0.3986418151088569 1.0 0.6913047992431163 7 O15400,P01889 2 +Negative regulation of protein localization to nucleus 0.5352608608708163 0.8419156910529858 0.3998351466671415 1.0 0.6923694567268001 8 P21359,Q9ULC3 2 +Regulation of cellular localization 0.3020517338831157 0.8418107748799726 0.3998938797684743 1.0 0.6923694567268001 240 Q96AC1,P05556,Q13277,Q10713,Q96ST3,P23634,O00410,P02786,Q07954,P21359,Q9Y6B6,P15311,O95071,Q96HY6,Q9Y5K6,Q16539,Q9Y3E7,O43464,Q92544,P19784,Q92783,Q96D46,P55786,Q8N183,P53350,P31751,P62258,Q9NV96,P11279,Q9Y282,P62942,O14777,O95251,P06493,O00264,P27105,P60604,O15400,Q9ULC3,Q9NQ11,Q9H4M9,P46934,P19022,P11234,P31749,O00560,Q9UN37,Q05D32 48 +Flavin containing compound metabolic process 0.522573030392451 0.8411476663840557 0.4002652143983294 1.0 0.6923877473429423 2 P55072 1 +Heart morphogenesis 0.5534315876351592 0.840648336113015 0.4005449714804292 1.0 0.6925757674203438 29 P09493,P62942,P98164,Q9UHI8,P10253,O94813 6 +Nuclear body organization 0.5268875370021368 0.8399236363569745 0.4009512040435086 1.0 0.6929100977762784 4 Q9BUR4 1 +Central nervous system neuron differentiation 0.5492512824215383 0.836639821260466 0.4027950549545278 1.0 0.695358209428262 20 Q8N3R9,P58546,Q8NCM8,Q04656,P43034,Q96ST3,Q6Y7W6,O14949,O94813 9 +Regulation of smoothened signaling pathway 0.5417499001609898 0.8296532463431553 0.4067348625579954 1.0 0.6997473454684329 14 Q86SX3,Q9Y297,Q7Z3E5 3 +Production of sirna involved in rna interference 0.524516523984474 0.8289665428218805 0.4071233395067291 1.0 0.700230631489777 4 Q15631 1 +Inorganic ion import across plasma membrane 0.5304755600919568 0.8279428154123379 0.4077028858464135 1.0 0.7010422046645939 7 P54709,P05026,P23634 3 +Regulation of multicellular organism growth 0.5436859735616797 0.8223795450242432 0.4108609173254296 1.0 0.7044257497467862 17 Q9C0B1,Q99538,O43464,P05067,P40763,O75844 6 +Cellular carbohydrate biosynthetic process 0.5466172604866437 0.8199139259024615 0.4122651773978973 1.0 0.7061932476073678 21 Q7LGA3,P31751,Q93063,P31749,O43505 5 +Heart growth 0.5383475739955375 0.8196174667891929 0.412434213118773 1.0 0.7061932476073678 13 P11413,P10644,Q16539,Q8NDZ4 4 +Urogenital system development 0.5357919607519338 0.8174263618092815 0.4136848156909001 1.0 0.7072363770265238 47 P21359,Q15375,P07602,P98164,Q9UHI8,O94813 6 +Regulation of non motile cilium assembly 0.5298174731091372 0.816380533578922 0.4142825267307359 1.0 0.7075599558630749 8 Q16181,Q9P2S5 2 +Positive regulation of alpha beta t cell differentiation 0.5279839728917983 0.8163162442501175 0.4143192859831093 1.0 0.7075599558630749 7 P04083 1 +Muscle tissue development 0.5086457290416352 0.8134009204266858 0.4159882317938441 1.0 0.7100375954320727 60 P05556,P98164,P14649,P21359,Q16539,P61586,P78310,Q14126,P11413,P60660,P62942,P06493,Q16527,Q8NDZ4,P41440,P58546,Q9BYT8,P09493,P10644,O75955,O75844 21 +Kidney epithelium development 0.5355531059158207 0.8129810289518496 0.4162289351165045 1.0 0.710262219556604 12 O94813 1 +Regulation of wnt signaling pathway 0.5283766795248587 0.812684595177341 0.4163989156449514 1.0 0.7102794884474595 51 Q16539,Q9BZK7,P19022,Q9NWU2,P05067,Q13641,O43293,Q07954 8 +Programmed necrotic cell death 0.5393170195781998 0.8119647136387811 0.416811879320583 1.0 0.7106980970081183 15 Q13572,Q13510,Q96HS1 3 +Carbohydrate transport 0.5448640158050191 0.8111751496916072 0.4172650943035376 1.0 0.7110044335366275 21 Q06481,Q99523,P31751,P31749 4 +Cellular response to acid chemical 0.5378531485885726 0.8109015012131473 0.4174222381210284 1.0 0.7110044335366275 14 Q04656,Q6IAA8,Q9UQB8,P17655,O00410 5 +Negative regulation of transmembrane transport 0.5452248872279339 0.8096790696046828 0.4181246505438722 1.0 0.7120040478787886 22 P31751,P62258,P46934,Q04656,P62942,P31749,Q06481,Q9P2B4 8 +Protein processing 0.5296149851098827 0.8093686142330433 0.4183031497905767 1.0 0.7121217325148155 50 Q99538,Q15392,O75503,P42892,O75976,P17655,Q92896 7 +Regulation of response to stress 0.2987024134839679 0.8085329176701862 0.4187838642962256 1.0 0.7123812272193438 252 Q08722,Q96AC1,P05556,O60313,P04062,P05067,Q04656,Q96ST3,Q06481,P08183,P23634,P08069,Q9NZ08,Q9UNS2,P10586,Q13619,Q8IZ81,Q9UJ14,P15311,O95071,Q16539,P28070,O43464,Q9Y4E8,P01889,P53634,Q07021,Q7Z4V5,P04083,Q9BY67,P11279,Q9UBB9,P67809,O95251,P13693,O43567,O96028,Q11206,P61160,P04439,P00374,Q9NUD5,Q7Z739,Q96G23,Q9NXR7,P26583,P31749,P46379,Q96T76,O00560,O75844,O75915,Q6UWE0,Q99543,Q96L91 55 +Positive regulation of monooxygenase activity 0.529783346396678 0.8080608519443679 0.4190555524574864 1.0 0.7126571699316188 9 P00374,Q8WTV0,P31749 3 +Cation transport 0.3120033056436809 0.8072329490557151 0.4195322860090713 1.0 0.7132815831598471 165 P05556,P08195,P30825,P54709,Q7KZN9,Q04656,Q9UNF1,P05067,P98164,P23634,P07384,P02786,Q9H2J7,P61586,Q13423,Q70HW3,Q99808,P11413,Q13555,P61421,P51790,P62258,O94886,P62942,P13693,P00403,Q8TAD4,P27105,O43772,Q9HC07,Q9NQ11,Q9NWR8,P35670,P06756,P46934,P31749,Q04917,Q96GC9,O75844 39 +Regulation of action potential 0.5308169169199347 0.805100519811224 0.4207616758713657 1.0 0.7149983059051399 10 P04062,P78310 2 +Cell cell adhesion mediated by cadherin 0.5253948961468052 0.8042592963319563 0.4212472398776308 1.0 0.7150768009396028 7 P19022,O75955 2 +Regulation of anion transport 0.5327365275089067 0.7995845605058375 0.4239515357868701 1.0 0.7174225365148231 12 P08183,P05556,Q7L0J3,Q15041 4 +Organic anion transport 0.5242056356013909 0.798367772183344 0.4246570996661267 1.0 0.7181045187068852 52 Q08722,P21359,P05556,Q9H2J7,P04083,P08195,P30825,P07602,Q9UBX3,Q7L0J3,Q15041,P98164 12 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.5450180615955763 0.7978996673574686 0.4249287164484803 1.0 0.7181427684526497 32 P62942,Q05D32,P98164,O00560,Q92896,P36896,Q92859,Q07954 8 +Snrna transport 0.5153482880755449 0.7972663535295054 0.4252963568865493 1.0 0.7185775456349431 3 Q9H814,P62826 2 +Fatty acyl coa metabolic process 0.5347544522061474 0.7960308208324975 0.4260141214635258 1.0 0.7190749079497272 14 Q9UMR5 1 +Regulation of striated muscle cell differentiation 0.533399295671861 0.7959663859539423 0.4260515733408665 1.0 0.7190749079497272 13 Q9BYT8,Q16539,P67809 3 +Intermediate filament bundle assembly 0.5147579693034123 0.7945672269880902 0.4268652886543118 1.0 0.7190749079497272 3 P58107,P07197 2 +Endoderm development 0.5316098118543705 0.7942342299666679 0.4270590846296613 1.0 0.7190749079497272 12 Q93074 1 +Positive regulation of mitotic cell cycle phase transition 0.5420606329253187 0.7930095732065989 0.427772245236969 1.0 0.7190749079497272 37 Q13619,P04083,Q9UJX5,Q9UJX4,P05067,Q13620,P06493,P31749,Q96ST3,Q9UHI8,Q9P258,Q96DY7 12 +Monoubiquitinated protein deubiquitination 0.5226696113881926 0.7915962663885795 0.4285961246341561 1.0 0.7190749079497272 7 Q96ES7 1 +Enamel mineralization 0.511360283269403 0.7898841322132625 0.4295954390875218 1.0 0.7190749079497272 2 Q6P4Q7 1 +Amelogenesis 0.511360283269403 0.7898841322132625 0.4295954390875218 1.0 0.7190749079497272 2 Q6P4Q7 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.5137057044839977 0.7897594585647252 0.4296682596905916 1.0 0.7190749079497272 3 O75844 1 +Regulation of myosin light chain phosphatase activity 0.5135215049768942 0.7889183249832271 0.4301597445710476 1.0 0.7190749079497272 3 Q13464 1 +Embryo implantation 0.5298214851517165 0.7857526560781158 0.4320124079702716 1.0 0.7190749079497272 12 Q96GC9,P36896,Q07021 3 +Terpenoid metabolic process 0.5400846176822918 0.7839903621031347 0.4330457655739939 1.0 0.7190749079497272 22 P98164,Q9HB40,Q07954 3 +Positive regulation of sprouting angiogenesis 0.509884921805847 0.7831757936485908 0.433523887552977 1.0 0.7190749079497272 2 P14618 1 +Regulation of actin filament bundle assembly 0.5413796150423442 0.7825949222501102 0.4338650242565838 1.0 0.7192414840617164 25 Q08722,Q96AC1,P60953,P35080,P09493,Q13464,P61586,Q13136,Q9Y624,O75116,Q13177 11 +Tooth mineralization 0.5115112160566502 0.779747724578943 0.4355393816311965 1.0 0.7201201646021362 3 Q6P4Q7,Q6W2J9 2 +Postsynapse organization 0.5396228757737335 0.7796246200366652 0.4356118599390495 1.0 0.7201201646021362 37 Q15375,Q9UQ16,Q99538,P19022,Q9UJU6,Q9NQX3,P43034,Q14444,P12814,Q16352,Q9UQB8,P08069,P61160 13 +Histamine production involved in inflammatory response 0.5112160566705911 0.7784027004726262 0.4363316472708085 1.0 0.7203763348997609 3 P51809,Q9UNH7 2 +Histamine transport 0.5112160566705911 0.7784027004726262 0.4363316472708085 1.0 0.7203763348997609 3 P51809,Q9UNH7 2 +Histamine secretion 0.5112160566705911 0.7784027004726262 0.4363316472708085 1.0 0.7203763348997609 3 P51809,Q9UNH7 2 +Negative regulation of striated muscle cell differentiation 0.51781343570582 0.7780628544297749 0.4365319596847359 1.0 0.7203763348997609 6 P67809 1 +Protein localization to cell surface 0.5356076795113835 0.7780468072571106 0.4365414195360302 1.0 0.7203763348997609 18 Q13277,P31749,Q92544 3 +Connective tissue development 0.5397676030148493 0.7766950825507237 0.4373386887776385 1.0 0.7210555311065722 24 Q16539,Q9BZK7,Q9C0B1,Q04656,Q9NX62,Q8N5W9,Q92896,O75844 8 +Regulation of monooxygenase activity 0.5293175799740235 0.7765302121307238 0.4374359893505173 1.0 0.7210555311065722 13 P00374,Q8WTV0,P31749,P06280 4 +Renal vesicle development 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Metanephric nephron development 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Metanephric nephron morphogenesis 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Metanephric renal vesicle morphogenesis 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Positive regulation of mesenchymal cell proliferation 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Regulation of epithelial cell differentiation involved in kidney development 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Cell differentiation involved in metanephros development 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Nephron tubule epithelial cell differentiation 0.5075243434641543 0.7724617492270547 0.4398409934845904 1.0 0.7225245691609318 2 P42224 1 +Proximal distal pattern formation 0.5075243434641491 0.7724617492270314 0.4398409934846041 1.0 0.7225245691609318 2 O94788 1 +Carbohydrate biosynthetic process 0.5251120952555063 0.7719584272476503 0.4401390504169122 1.0 0.7227482207046314 49 Q7LGA3,P31751,Q9BYT8,Q93063,P31749,Q9NRB3,P15291,Q92520,O43505,Q11206,Q8NCH0 11 +Positive regulation of cell cycle g2 m phase transition 0.5309832811793433 0.7718569028565062 0.4401991851142648 1.0 0.7227482207046314 15 Q96ST3,P05067,Q9P258,P06493 4 +Organophosphate ester transport 0.5398403815354221 0.769774217858038 0.441433835925145 1.0 0.724227387064691 31 Q08722,Q9NV96,Q14108,Q8WTV0,P61916,Q96GC9,P08183,Q8NB49 8 +Lipid homeostasis 0.5395540567685981 0.7682719653720431 0.442325626451677 1.0 0.7250039230625566 29 Q9Y6B6,P04114,Q9NQ11,Q9H4M9,O15118,Q8WTV0,P61916,Q5BJF2,O15260,Q9BWH2 10 +Regulation of alpha beta t cell differentiation 0.5194858569846766 0.7682265140551527 0.4423526240252649 1.0 0.7250039230625566 8 P04083 1 +Stress fiber assembly 0.5389780212330969 0.7670320227575803 0.4430624763516562 1.0 0.725984576151342 27 Q08722,Q96AC1,P05556,P60953,P35080,P09493,Q13464,P61586,Q13136,Q9Y624,O75116,Q13177 12 +Rna interference 0.522632817386331 0.76666756306762 0.4432791939894707 1.0 0.7261569081206478 10 Q15631,Q5KU26 2 +Gastrulation with mouth forming second 0.50767414403778 0.7622921255211369 0.4458856726160025 1.0 0.7295088536643652 3 Q4VCS5,O60701 2 +Negative regulation of epithelial cell differentiation 0.507674144037761 0.7622921255210514 0.4458856726160536 1.0 0.7295088536643652 3 P42224,Q13247 2 +Regulation of peptidyl tyrosine phosphorylation 0.5371414155800384 0.7611321502406512 0.4465781391477379 1.0 0.7301542318762775 25 Q15375,Q9H223,P05067,Q9BRG1 4 +Rap protein signal transduction 0.5074044561520168 0.7610677311800578 0.4466166131077322 1.0 0.7301542318762775 3 Q9Y4G8 1 +Dicarboxylic acid transport 0.5323716612143361 0.757590726950145 0.4486960332239733 1.0 0.7324501445055331 19 P21359,P41440,P05556,Q9UBX3,Q15041,P98164 6 +Regulation of leukocyte mediated immunity 0.5374635936077299 0.7571496694559808 0.4489601995888181 1.0 0.7326976433500141 30 Q9BY67,P11279,P01889,O15400,P02786,P04439 6 +Regulation of ras protein signal transduction 0.5356737594773863 0.7537182750715136 0.4510184059357758 1.0 0.7351852736971733 25 P21359,Q15555,Q9H3F6,P05556,P41440,O75955,Q68EM7,Q9Y624 8 +Skin epidermis development 0.524350828830433 0.7529758797743707 0.451464408443488 1.0 0.7353312939849814 13 P21359,Q04656,P36896 3 +Glycosylation 0.5148137119465599 0.7517592507329393 0.452195851502883 1.0 0.7357378601664548 53 O60512,Q86SF2,O15118,P04062,Q93063,Q16706,O75503,P15291,Q10472,Q10471,O43505,Q11206 12 +Phototransduction visible light 0.5075090506458111 0.7510121261452635 0.4526453580261571 1.0 0.7357917105353016 4 Q15555 1 +Peripheral nervous system development 0.5266211335623436 0.7509803436567798 0.4526644855136532 1.0 0.7357917105353016 15 Q8N3R9,P21359,Q9UPY3,P31751,Q93074,P31749,P06493,P51648 8 +Organism emergence from protective structure 0.5095816783693393 0.7501977103970167 0.4531356375800013 1.0 0.7363736896270117 5 Q8IWS0,Q9BZK7 2 +Defense response to bacterium 0.5230882103990578 0.7470058147248653 0.4550600509071638 1.0 0.7385791402158157 13 Q5KU26 1 +Positive regulation of protein localization to cell periphery 0.5306223544503655 0.7446732945380519 0.4564692471966589 1.0 0.7400444407695045 20 P05556,Q13277,P31749,O00264,P23634,Q07954 6 +Cell fate commitment involved in formation of primary germ layer 0.5079740106320122 0.7428663356507389 0.4575626088951088 1.0 0.7400444407695045 5 Q92541,Q6P1J9,Q6PD62,Q8N7H5 4 +Endodermal cell fate commitment 0.5079740106320122 0.7428663356507389 0.4575626088951088 1.0 0.7400444407695045 5 Q92541,Q6P1J9,Q6PD62,Q8N7H5 4 +Response to bmp 0.528273385527966 0.7424106301687907 0.4578385808956491 1.0 0.7400444407695045 18 P98164,Q92859 2 +Female sex differentiation 0.5234502584521056 0.7421209972759342 0.4580140290550152 1.0 0.740052452009965 14 P98164,O94813 2 +Meiotic chromosome condensation 0.507383343177776 0.740175851186109 0.459193298541634 1.0 0.7408178874395994 5 Q15003,Q9NTJ3,O95347,P42695 4 +Sensory perception of mechanical stimulus 0.5242775471503391 0.7398003409447627 0.4594211521144757 1.0 0.7408550161667666 15 P98164,Q14108 2 +Protein localization to cilium 0.5197866707097669 0.7384163262641587 0.4602614964997067 1.0 0.7418426200081928 12 Q9UPT5,Q10713,Q8NCM8,Q9H4M9,Q96C92 5 +Endosomal transport 0.4387422289573244 0.7336884100494571 0.4631386638036354 1.0 0.7459259528356424 78 O60784,Q99523,Q9H4M9,Q9Y3E7,Q9C0C9,O75503,Q13190,Q8NBN3,Q9H223,O15260,Q9BRG1,Q9UN37,O43752,Q15904,Q4J6C6 15 +Regulation of cell junction assembly 0.5325716638066375 0.7321046566184837 0.4641046918165687 1.0 0.7469882232080004 32 Q96AC1,Q15375,P41440,P05067,Q13641,O75955,O43293,Q9Y624,Q9P258 9 +Nik nf kappab signaling 0.5271260195813576 0.7320427879450008 0.4641424520547406 1.0 0.7469882232080004 19 O15111,P15311,Q9UPY3,Q99829,P05067,P31749,P61586 7 +Vascular endothelial growth factor receptor signaling pathway 0.508765451745433 0.7274903800525012 0.4669256063143954 1.0 0.7507250425059803 7 Q16539 1 +Reactive nitrogen species metabolic process 0.5248180729032245 0.7257088483424532 0.4680172762673913 1.0 0.7522944366668438 18 P31749,P06280 2 +Positive regulation of synaptic transmission gabaergic 0.4969017409265325 0.7245650561203469 0.4687189028670353 1.0 0.7530503597394866 2 P33176 1 +Cochlea development 0.5038566761371316 0.7241476852181441 0.4689750719862338 1.0 0.7532760223613082 5 P33993,P43034 2 +Bone development 0.5305895111690234 0.7219574097532068 0.4703206630615919 1.0 0.7550647389718775 29 Q16539,Q32P28,Q93063,O96028,Q9NX62,Q9ULC3,O75844,Q8N5W9,Q92896,Q15904,Q15125 11 +Regulation of mitotic cell cycle phase transition 0.3238319383116001 0.7202203342875754 0.4713893459433489 1.0 0.7560346494435086 101 P05067,Q96ST3,Q06481,O60921,Q13564,Q9P258,Q13619,Q9UJX4,Q96DY7,P04083,P53350,O14777,P06493,Q9UHI8,Q9UJX5,Q9NXR7,P31749,O60934,Q9UN37 19 +Oligodendrocyte differentiation 0.5249732231713736 0.7170877387404301 0.4733199608308802 1.0 0.7582312595492366 20 P21359,Q92542 2 +Sequestering of metal ion 0.4975269476364811 0.7164631314650806 0.4737054249914778 1.0 0.7582312595492366 3 Q8NEW0 1 +Regulation of intracellular transport 0.305120377014581 0.7148911286914787 0.4746763191475107 1.0 0.7587071116554351 123 Q15154,Q9BWF3,O00410,P46060,P21359,Q9Y6B6,P15311,O95071,Q16539,Q9Y3E7,O43464,Q9H3S7,Q92544,P19784,P55786,P31751,P62258,Q9NV96,P11279,Q9Y282,P06493,P27105,P60604,Q9ULC3,Q9NQ11,Q9H4M9,P46934,Q92688,Q9UL25,Q05D32 30 +Negative regulation of cell substrate adhesion 0.5097501088443064 0.7148734233221203 0.4746872604873406 1.0 0.7587071116554351 9 P21359,Q9P258,P61586 3 +Negative regulation of mrna processing 0.5263869007339029 0.7127065636713139 0.4760273540412241 1.0 0.7604399740128326 23 Q5VTR2,Q07021,P18615 3 +Utp biosynthetic process 0.5012124528402981 0.7121716253518106 0.4763585053375001 1.0 0.760631314630151 5 O75414 1 +Medium chain fatty acyl coa metabolic process 0.4939510179994141 0.7113598180139967 0.47686129225437 1.0 0.7608742677882228 2 O00154 1 +Endothelial cell migration 0.5264721264362965 0.7078910269571296 0.4790129324070165 1.0 0.7633718947294192 37 P21359,P04083,Q16539,Q99538,Q8WTV0,P31749,Q13685,Q5JRA6,P42785,O94813 10 +Response to abiotic stimulus 0.2959479472837139 0.7075331007643354 0.4792352500674122 1.0 0.7634096048578671 232 P05556,Q7L576,P05067,P04062,Q04656,O60921,Q06481,P08183,P23634,P08069,Q9UNS2,Q9Y624,P02786,P21359,Q16539,Q99538,O43464,Q13620,P61586,Q92544,P16989,P51797,P19021,P55786,Q15904,Q99808,Q15555,Q70UQ0,P04083,Q13144,Q96KB5,P31751,P61421,P62258,Q9Y487,P00403,P58546,Q9NXR7,P46934,P19022,P31749,P51798,O95831,O60884,P17655,P29992,Q9BRK5,O75844,Q99543 49 +Positive regulation of nf kappab transcription factor activity 0.526446277396391 0.7073430709214269 0.4793533056381092 1.0 0.7634096048578671 25 P41440,O15111,P58546,Q96HY6,Q14254,P05067,O75955,P40763,P02786 9 +Lung alveolus development 0.4997742798667232 0.7056734327257493 0.4803912462694777 1.0 0.7640631266749154 5 Q04656,Q16706 2 +Rna guanine n7 methylation 0.4972125690951472 0.7044577810493323 0.4811477333329317 1.0 0.7647147812493617 4 Q9UBP6 1 +Positive regulation of collagen metabolic process 0.4918855119504393 0.7021438326497608 0.4825894692008607 1.0 0.7655042416300701 2 P08670 1 +Eyelid development in camera type eye 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.7655042416300701 2 Q13547 1 +Skin development 0.5240728638095143 0.7011552089418516 0.483206159149687 1.0 0.7658365323893678 39 P21359,P04083,P23229,Q16739,Q04656,P04062,Q13510,Q15392,Q8NEY8,Q15185,P36896 11 +Biological process involved in interaction with host 0.4984190784950521 0.6994781697167263 0.4842532510758222 1.0 0.7670288721419957 57 P07858,P08195,P11279,O15118,Q14108,Q8WTV0,Q9BTY2,P78310,Q9Y624,P02786 10 +Regulation of protein localization to plasma membrane 0.5262012963752996 0.6985314556443231 0.4848448931702875 1.0 0.7675924743527656 31 P05556,Q13277,P15311,P31749,O00264,P23634,Q9UN37,O15400,Q13136,Q07954 10 +Negative regulation of microtubule polymerization 0.4979326639102072 0.697368727379607 0.4855720672718204 1.0 0.7682126944559142 5 Q02790,P04350,Q15691,Q9BTW9 4 +Positive regulation of potassium ion transport 0.504084184031792 0.6973390004756472 0.4855906663112268 1.0 0.7682126944559142 8 P54709,Q9H4A3,P05026,P50570,P33176 5 +Ensheathment of neurons 0.5254740248405391 0.6950254088225312 0.4870393782544306 1.0 0.7701302774924323 30 P21359,P31749,P07686,P53634,Q92542 5 +Isoprenoid metabolic process 0.5247814996855137 0.6932852096546196 0.4881305829991855 1.0 0.7703863318327241 28 P98164,P61916,Q9HB40,Q07954 4 +Stem cell division 0.4969044298350011 0.6927401096074945 0.4884726630301101 1.0 0.7703863318327241 5 Q6GMV2 1 +Ceramide biosynthetic process 0.5114757956162973 0.6924691883595286 0.4886427289671182 1.0 0.7703863318327241 13 P04062,Q13510,O60512,Q16739 4 +Microtubule anchoring 0.5083092306763394 0.6923494098929335 0.4887179279159981 1.0 0.7703863318327241 11 Q9Y496,Q86VS8,Q8TD16,Q14203,Q15154 5 +Fatty acid transmembrane transport 0.5029280537243278 0.692067306896641 0.4888950615920122 1.0 0.7703863318327241 8 O43772,P31751,P31749 3 +Ectodermal placode development 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Tongue morphogenesis 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Fungiform papilla development 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Hair follicle placode formation 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Tongue development 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Fungiform papilla morphogenesis 0.4920306965761504 0.6918613063253972 0.4890244320799328 1.0 0.7703863318327241 3 Q13547,P35222 2 +Positive regulation of behavior 0.4920306965761463 0.6918613063253799 0.4890244320799437 1.0 0.7703863318327241 3 Q9Y6A4,Q96QK1 2 +Cell cell adhesion mediated by integrin 0.4920056048536581 0.6917493769174564 0.4890947326366588 1.0 0.7703863318327241 3 P05556 1 +Pteridine containing compound biosynthetic process 0.504162507454479 0.6892312635010331 0.4906777457185303 1.0 0.7719357593039395 9 P00374,P61457 2 +Lymphocyte activation involved in immune response 0.5236419802933553 0.6890530589983155 0.4907898783039948 1.0 0.7719357593039395 27 P04083,P11279,Q04656,P40763,O96028,P02786 6 +Regulation of cation channel activity 0.5169255742355515 0.687789713886985 0.4915852145228365 1.0 0.7725574713324725 18 P07384,P05067,P27105,P62942 4 +Cellular response to interferon beta 0.5000233317435719 0.6876712209659159 0.4916598469632003 1.0 0.7725574713324725 7 P17655,P60604 2 +Response to interferon beta 0.5000233317435719 0.6876712209659159 0.4916598469632003 1.0 0.7725574713324725 7 P17655,P60604 2 +Peptidyl diphthamide biosynthetic process from peptidyl histidine 0.4880495721451733 0.6850914347671426 0.4932862248126741 1.0 0.7744121443355477 2 Q9BQC3 1 +Regulation of fatty acid biosynthetic process 0.4946780989845689 0.6827387682290629 0.4947719276828135 1.0 0.7745543500269484 5 P04083 1 +Negative regulation of chromatin binding 0.4899645808736567 0.682656850979021 0.4948237012684542 1.0 0.7745543500269484 3 Q7Z5K2,Q08209 2 +Positive regulation of cell junction assembly 0.5042981707226889 0.6817004855327968 0.4954283603908587 1.0 0.774953456275839 10 P41440,O75955,Q13641 3 +Negative regulation of calcium mediated signaling 0.489743162403186 0.6816719088961131 0.4954464339508513 1.0 0.774953456275839 3 P23634 1 +Negative regulation of calcineurin mediated signaling 0.489743162403186 0.6816719088961131 0.4954464339508513 1.0 0.774953456275839 3 P23634 1 +Regulation of endocytosis 0.5097300957215474 0.6798921600668888 0.4965727461266771 1.0 0.7757831958926489 49 P06756,P05067,Q9H223,Q06481,O00560,P50897,Q6UWE0,Q07954 8 +Regulation of inflammatory response to antigenic stimulus 0.4959471243616455 0.6784070633060401 0.4975136318667312 1.0 0.7765077303889764 6 P28070 1 +Secondary metabolic process 0.5034244006188585 0.6776959957622914 0.4979644658308262 1.0 0.7768388863068963 10 P19021 1 +Inorganic anion transport 0.5208389320517435 0.6769663216365813 0.4984273227226681 1.0 0.7773684245054066 26 Q9H813,Q9UHG3,Q9UBX3,P51790,Q9C0H2,P51798,P51797 7 +Cardiac muscle tissue development 0.5215875000653487 0.6750531473029487 0.4996419992410303 1.0 0.778137835536529 30 P05556,Q16539,P09493,P10644,P62942,P06493,P98164,Q8NDZ4,P78310,Q14126,P11413 11 +Regulation of transmembrane transport 0.4391845842552643 0.674913706882967 0.4997305915233321 1.0 0.778137835536529 76 P05556,P54709,Q04656,P05067,Q06481,P08183,P07384,Q16539,P11413,P31751,P62258,P62942,Q8TAD4,P27105,Q9P2B4,P46934,Q15041,P31749,Q04917,Q96GC9,O75915,O75844 22 +Peptidyl histidine modification 0.4881936245572634 0.6747871443901843 0.4998110091427188 1.0 0.778137835536529 3 P22392,Q9BQC3 2 +Regulation of cytoplasmic translational elongation 0.488193624557263 0.6747871443901822 0.4998110091427201 1.0 0.778137835536529 3 Q9BQC3,P49588 2 +Synaptic signaling 0.3425712321888346 0.6731473653733342 0.5008535429912897 1.0 0.7791055113197839 97 P05556,Q13277,P05067,Q13641,Q5SQN1,P21359,Q99538,P50897,P51790,Q7L0J3,P56545,O60333,Q14168,P41440,Q9UBB6,P19022,O75955,P31749,Q04917,O00560,Q9UQB8,P29992,Q92542,Q4J6C6 24 +Anaphase promoting complex dependent catabolic process 0.5022063266682174 0.6721210324497097 0.501506647852789 1.0 0.7795626259602809 10 P53350,Q9UJX4,Q9UJX5 3 +Intracellular protein transport 0.2923160313505903 0.6697040139950858 0.5030464923625395 1.0 0.7813964841995067 342 Q13277,Q99523,Q8TAG9,Q13190,Q06481,Q9H173,O43752,P21359,O60830,O15027,Q9Y6B6,Q16539,Q14108,O43464,Q92544,P19784,P20645,P55786,P84085,Q15070,Q15904,Q99595,P10619,P31751,P13473,Q9NV96,P62258,Q9Y282,P40855,Q86Y82,P27105,O15260,P60604,Q14168,O15400,Q9NQ11,Q9H4M9,P46934,Q15041,P31749,P46379,P31946,O00560,P40763,Q9BRG1,Q9UN37,Q92572,O95831,Q05D32 49 +Regulation of protein stability 0.2975262716842443 0.6692952713970711 0.5033071425866282 1.0 0.7814284517622109 109 O95816,P54709,Q14254,O15164,Q9H2J4,Q9UNS2,O15027,Q96HY6,P53350,P10619,P13473,P11279,Q9Y297,Q32P28,O14777,P40855,O95785,Q86Y82,P48449,P41440,O75955,P46379,Q15185,Q99747,Q9UL25 25 +Positive regulation of adaptive immune response 0.5105729280910319 0.6688338372546078 0.5036014792701209 1.0 0.7816990057340217 16 O15400,P01889,P02786,P04439 4 +Mannose metabolic process 0.4891223291510176 0.6682803088078809 0.5039546803426886 1.0 0.7818422178838618 4 O00754 1 +Negative regulation of potassium ion transport 0.4842136323399334 0.6681246344567934 0.5040540381656786 1.0 0.7818422178838618 2 Q12955 1 +Negative regulation of potassium ion transmembrane transport 0.4842136323399334 0.6681246344567934 0.5040540381656786 1.0 0.7818422178838618 2 Q12955 1 +Positive regulation of extracellular matrix disassembly 0.483623487754503 0.6655222382155824 0.5057165247016342 1.0 0.7833215850486537 2 Q7Z460 1 +Response to dopamine 0.5041166817083901 0.6655015660374607 0.505729742236481 1.0 0.7833215850486537 12 Q92542,P29992 2 +Superoxide metabolic process 0.4969703083692746 0.6650230798054598 0.5060357312201185 1.0 0.7833274169602825 8 P00374 1 +Receptor localization to synapse 0.5084228997561715 0.6649097837331613 0.5061081976175281 1.0 0.7833274169602825 15 O15400,Q13277,Q9NQX3 3 +Regulation of dna directed dna polymerase activity 0.4988130581771244 0.6648474605298637 0.5061480630923736 1.0 0.7833274169602825 9 P40937,Q9BRT9,P40938,P0CG13,Q9BRX5 5 +Histone monoubiquitination 0.5022224674452379 0.6643323509019253 0.5064776198251777 1.0 0.7833704697766647 11 Q5VTR2,Q13620 2 +Positive regulation of synaptic plasticity 0.4858323494686973 0.6643234682885633 0.50648330373118 1.0 0.7833704697766647 3 Q16643,P46821 2 +Positive regulation of cytoplasmic transport 0.4925702316517731 0.6632471541553477 0.5071722758431776 1.0 0.783877377905766 6 P15311,Q9H3S7 2 +Positive regulation of early endosome to late endosome transport 0.4925702316517731 0.6632471541553477 0.5071722758431776 1.0 0.783877377905766 6 P15311,Q9H3S7 2 +Regulation of actin filament based process 0.3826013269910799 0.6628718440181737 0.5074126357498141 1.0 0.7839596462658284 89 Q08722,Q96AC1,Q9NUQ9,Q7L576,Q9UJU6,Q14019,O15511,Q13576,Q9Y624,Q07954,P15311,Q9Y5K6,Q13464,P61586,O43293,P19021,Q14126,O94813,P60953,Q68EM7,Q13136,P58546,P52565,P09493,Q9UQB8 25 +Post embryonic development 0.5105079071361684 0.6627054910482684 0.5075191923278726 1.0 0.7839596462658284 17 P11717,Q9NX62 2 +Endothelial cell proliferation 0.5113551117133117 0.6612366957581532 0.5084605315312847 1.0 0.7849366991388814 18 P21359,P40763,Q8WTV0,P31749 4 +Cellular response to prostaglandin stimulus 0.4897349488628829 0.6606369137147581 0.508845190150347 1.0 0.7851581388667359 5 P31749 1 +Regulation of oxidoreductase activity 0.5116908415741247 0.6576987215242588 0.510731744045889 1.0 0.7873931041300852 19 P00374,P06280,Q8WTV0,P31749,Q15070 5 +Protein k48 linked ubiquitination 0.499030506214586 0.6576276366605875 0.5107774314502842 1.0 0.7873931041300852 10 P60604,Q15386,O95071,Q9Y297 4 +Negative regulation of leukocyte cell cell adhesion 0.5052428546089994 0.6566211265419819 0.5114245611225376 1.0 0.7880174894456143 14 P04083,P10644,P31749 3 +Positive regulation of cytoplasmic translation 0.501912290986883 0.6553565304631507 0.5122382320211052 1.0 0.7882896418609829 12 Q9H074,P67809 2 +Folic acid containing compound metabolic process 0.5049521985509972 0.6552716349579508 0.512292879961314 1.0 0.7882896418609829 14 P00374,P41440,Q92820,P34896 4 +Pteridine containing compound metabolic process 0.5096809138197288 0.6532927279064394 0.5135675797176869 1.0 0.7894300444910889 18 P00374,P41440,Q92820,P61457,P35270,P34896 6 +Multicellular organismal response to stress 0.4941974430261461 0.6525088440544811 0.5140729693979833 1.0 0.7894300444910889 8 P31749 1 +Pyrimidine ribonucleoside triphosphate biosynthetic process 0.4941831041423998 0.652444255988388 0.5141146224848958 1.0 0.7894300444910889 8 P15531,P17812,O75414 3 +Positive regulation of neurogenesis 0.5119403302683302 0.6513626071867556 0.5148124426325125 1.0 0.7899597114083298 43 P39880,Q9UPY3,Q9UJU6,Q16706,P98164,Q14444,A0MZ66,Q9UQB8,P55209,P61160,O94813 11 +Spinal cord development 0.5039868447787306 0.6507933746452141 0.5151798776205463 1.0 0.7902500007798672 14 P21359,Q93074,Q14203 3 +Molting cycle 0.5022647199994947 0.649740357547283 0.5158599504342898 1.0 0.7911067791112429 13 P21359,Q04656,P36896 3 +Regulation of b cell mediated immunity 0.4987564633687519 0.6484781259456222 0.5166757541249791 1.0 0.7914890062396224 11 P02786 1 +Regulation of isotype switching 0.4987564633687519 0.6484781259456222 0.5166757541249791 1.0 0.7914890062396224 11 P02786 1 +Negative regulation of mitochondrion organization 0.5061838708509162 0.6482261766052332 0.5168386736596982 1.0 0.7914890062396224 16 Q99536,P31749,P02786 3 +Positive regulation of protein export from nucleus 0.4949085226689856 0.6471591899700155 0.5175289206147848 1.0 0.7923596597371235 9 Q05D32 1 +Leukocyte proliferation 0.5145976325460666 0.6463958862413288 0.5180230038844624 1.0 0.7928492408415538 38 P04083,Q9BY67,P04062,Q92542,P02786,P04439 6 +Positive regulation of interleukin 2 production 0.4885633702320834 0.645350283385471 0.5187002139364325 1.0 0.7928908682436965 6 P04083 1 +Multicellular organism aging 0.498051885931896 0.6452644993075052 0.5187557943714021 1.0 0.7928908682436965 11 P04062,P29992 2 +Interstrand cross link repair 0.4839090640684852 0.6451763067346419 0.5188129385037845 1.0 0.7928908682436965 4 Q9H1E3,Q9BXW9,P55072 3 +Regulation of erbb signaling pathway 0.4979875510559551 0.6449712222616526 0.5189458349896117 1.0 0.7928908682436965 11 Q99538 1 +Response to antibiotic 0.4961193002505819 0.6443968623173307 0.5193181186764306 1.0 0.7932334473448062 10 P50416,Q04656,P61160,O95251 4 +Organic acid transport 0.5007079494587146 0.6441339959892879 0.5194885470852033 1.0 0.7933076334798672 51 P21359,Q9H2J7,P05556,P04083,P41440,P31751,P08195,P30825,Q9UBX3,Q7L0J3,Q15041,P31749,P98164,Q6P4A7,P08183,P29375 16 +Rho protein signal transduction 0.5119668055011819 0.6419374353324409 0.5209138065289252 1.0 0.7945560553252916 23 P41440,Q9H3F6,P05556,P52565,O75955,Q13464,P61586,A0MZ66,Q9Y624 9 +Sphingomyelin biosynthetic process 0.4830233244759456 0.6412681755987829 0.5213484620374023 1.0 0.7948409582513108 4 O15270,O15269,Q9P0L0 3 +Regulation of endoplasmic reticulum tubular network organization 0.4849548245642253 0.6394081559328755 0.5225574445894174 1.0 0.7959403285627299 5 Q15041,Q9H2M9 2 +Folic acid metabolic process 0.49080935746103 0.6372842358782319 0.5239397173420639 1.0 0.7971359431650156 8 P00374,P41440,P34896 3 +Positive regulation of erythrocyte differentiation 0.5010619900603592 0.6372613236039756 0.5239546391402614 1.0 0.7971359431650156 14 P40763,P36896,Q16539,O95251 4 +Mapk cascade 0.3498934128508202 0.6357805419022963 0.5249194716760384 1.0 0.798231132503809 95 Q96AC1,Q15375,P18615,P63104,P04062,P05067,Q13641,O75787,Q9H4H8,P08069,P21359,P15311,Q16539,Q96KB5,P62258,Q96S59,P06493,Q6IAA8,P06756,P19022,P43034,O00560,O75915 23 +Regulation of protein glycosylation 0.4765417527294171 0.6344658338006097 0.5257768573253556 1.0 0.7987881776401552 2 Q9UHD1 1 +Positive regulation of protein glycosylation 0.4765417527294171 0.6344658338006097 0.5257768573253556 1.0 0.7987881776401552 2 Q9UHD1 1 +Positive regulation of phosphorus metabolic process 0.3009738244033895 0.6330153698082006 0.5267236061248057 1.0 0.7994802228660493 132 Q96AC1,Q15375,P04062,P05067,Q96N67,Q9H223,P23634,P08069,P02786,Q96HY6,P23229,P53350,P31751,P00403,Q8NDZ4,P41440,P11234,O75955,P31749,Q15185,O00560,O60934,P17655 23 +L glutamate transmembrane transport 0.4872175845746911 0.6301450464450805 0.528599689616684 1.0 0.8013935676303243 7 O75915,P05556,Q15041 3 +Regulation of mrna polyadenylation 0.5008670218242768 0.6297357448908089 0.5288674917429499 1.0 0.8016128920248203 15 Q5VTR2 1 +Adrenergic receptor signaling pathway 0.479521193084464 0.6258669538541767 0.5314022114633183 1.0 0.8042981438041981 4 P23634 1 +Glycosyl compound catabolic process 0.4937834868883314 0.6258654481231031 0.5314031991724162 1.0 0.8042981438041981 11 P04062,P04066,Q9BTY2,P06280 4 +Regulation of t cell proliferation 0.503838607915376 0.6257118875285279 0.5315039346613917 1.0 0.8042981438041981 18 P04083,P10644,P02786,P04439 4 +Epiboly 0.4861389551153934 0.625347732463453 0.5317428584565245 1.0 0.804472695457117 7 Q96AC1 1 +Regulation of hormone metabolic process 0.4837674629948136 0.6240662707734059 0.5325840638348467 1.0 0.8051839887517074 6 P08069 1 +Secretion 0.3011801396020839 0.6235395139984692 0.5329300443747385 1.0 0.8052285652032167 162 O15126,O60645,Q13277,Q15334,Q8TAG9,Q04656,Q5SQN1,Q9UNS2,P21359,P15311,Q9Y5K6,Q9Y3E7,Q9H3S7,Q92783,P19021,P50897,P20645,Q99808,Q8N183,P04083,Q13555,P11279,Q7L0J3,Q32P28,P56545,P52789,Q68EM7,P00403,Q5JRA6,Q9UN37,Q9NQ11,P35670,O95486,P11234,P43034,P11233,Q9UBF2,O00560,Q9UL25,Q9BRK5,P50416,Q4J6C6 42 +Forebrain development 0.4585349278857872 0.6199325975724019 0.5353021634613271 1.0 0.8068573938720165 68 Q04656,P05067,Q96N67,P98164,Q96ST3,P23634,O15511,P08069,P21359,O43464,P61586,P19784,O94813,Q13144,P62258,Q8N3R9,Q8NCM8,P19022,P43034,Q96N66,O14949,Q15154 22 +Neurotransmitter transport 0.5108649686909367 0.6196739950651002 0.535472439817984 1.0 0.806927218336823 31 Q9H2J7,P21359,P05556,Q13277,Q7L0J3,P56545,O75955,Q5SQN1,P50897,Q4J6C6 10 +Establishment or maintenance of monopolar cell polarity 0.4885696781051365 0.6186535908915112 0.5361445893245214 1.0 0.807566237043645 9 P15311,P60953,Q13308,P61586 4 +Negative regulation of production of mirnas involved in gene silencing by mirna 0.4746730196672147 0.615356279854482 0.5383194576456853 1.0 0.8097180381870174 3 O75844 1 +Polyol metabolic process 0.5081356503296132 0.6139703842089067 0.5392348977855672 1.0 0.8109076425465563 26 P00374,P04062,Q13510,Q9NX62,P61457,Q9BW91,Q13572 7 +Leukocyte cell cell adhesion 0.5058386583615363 0.6126394812894913 0.5401147465276481 1.0 0.81185569150196 42 Q9NUQ9,Q08722,P05556,P04083,P15311,P30825,Q14254,P23396,P10644,P31749,P61586,Q11206,Q5JRA6,Q9Y624,P02786,P04439 16 +Positive regulation of protein tyrosine kinase activity 0.4738102292849909 0.6116057011457251 0.5407986651871628 1.0 0.81269605502503 3 Q15334 1 +Regulation of microtubule depolymerization 0.4866942637492638 0.6102725303361823 0.5416812904772765 1.0 0.81351193404242 9 P29372,P46821,Q66K74,Q92974,Q9ULW0,O15344,Q7Z460,Q8WWK9 8 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4966391965647978 0.6102194122031168 0.5417164722079708 1.0 0.81351193404242 15 P36896,Q92859,O00560 3 +Actin filament based movement 0.5081296294542486 0.6095203513747193 0.5421795873725208 1.0 0.8140196295652931 28 Q5T0N5,P35580,P60660,Q9UM22,P09493,Q9UH99,Q13464,A0MZ66,O43707,P15924,P14649,Q14126 12 +Transforming growth factor beta receptor signaling pathway 0.5069644198580672 0.6082168072967238 0.5430436888193837 1.0 0.8149410821148428 26 P05556,P62942,Q9Y4E8,Q06481,O00560,P40763,Q92896 7 +Regulation of mitotic recombination 0.4753469146737484 0.6076204395048626 0.5434392413854761 1.0 0.8153021562696183 4 Q92878,Q15554,P18074 3 +Synaptic transmission dopaminergic 0.4776990624630711 0.6074764437816744 0.5435347708464122 1.0 0.8153021562696183 5 O75955 1 +Female gamete generation 0.5055256413501177 0.6071968508520914 0.5437202818995903 1.0 0.8153925443829378 24 P53350,O14777,P07686,Q9UHI8,Q9Y2W6 5 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4818112482811383 0.6061810338058173 0.5443945456956631 1.0 0.8160277440660297 7 P31749 1 +Negative regulation of cellular component organization 0.297209907408828 0.605931624686411 0.5445601582593198 1.0 0.8160880824742569 178 Q15375,O75414,Q9UQ16,O60313,P04062,P05067,Q99536,Q9Y624,Q9P258,P02786,Q99471,P61586,O94813,Q96DY7,P53350,Q9UBB9,Q9H3K2,O14777,O00264,Q86X55,Q96G23,P58546,P06756,P31749,Q04917,O00560,O60934,Q6UWE0 28 +Epithelial cell proliferation involved in lung morphogenesis 0.472142683425456 0.6043720310666375 0.5455963264769761 1.0 0.8170766241925729 3 P60953 1 +Negative regulation of microtubule polymerization or depolymerization 0.4922768128711813 0.6040190037479309 0.5458310076720672 1.0 0.8172400781842588 13 P29372,P46821,Q92974,Q02790,O15344,Q9BTW9,P04350,Q8WWK9 8 +Organelle membrane fusion 0.5064902316743746 0.6029039406432005 0.5465725943266608 1.0 0.8175982511641916 38 P04083,Q13277,O15400,P31751,Q9NQ11,Q13190,Q5SQN1,Q86Y82,Q9UN37,O43752 10 +Single fertilization 0.5038444765973628 0.6026551067821756 0.546738152480793 1.0 0.8176580226625231 23 P15291,Q08431,P07686 3 +Establishment of spindle orientation 0.4901895023593158 0.6019382162173312 0.5472152644498003 1.0 0.8178265056137597 12 P53350,P05556,P43034,O14777,Q14203 5 +Erk1 and erk2 cascade 0.5061750637112938 0.599124668164881 0.5490897528499343 1.0 0.8202327423251657 37 Q96AC1,Q15375,P18615,Q96S59,P06756,P05067,Q13641,P06493,Q9H4H8 9 +Negative regulation of blood vessel endothelial cell migration 0.4779559258402158 0.5984880551732273 0.5495143267295082 1.0 0.8203022854870667 6 P14923,P23634,P61586 3 +Negative regulation of protein acetylation 0.4837948316463019 0.5973647741574017 0.5502638667969773 1.0 0.8212328686034667 9 Q9BX68,Q01105 2 +Transition metal ion transport 0.4945963211465256 0.5944293716546215 0.5522249683611096 1.0 0.8235932517825483 16 Q9HC07,Q8NEW0,P35670,Q04656,Q8TAD4,P02786 6 +Rna polyadenylation 0.5058283640014748 0.5937710117725702 0.552665280037594 1.0 0.824013225082653 34 Q5VTR2,P05067,Q5KU26 3 +Positive regulation of leukocyte proliferation 0.4935370309960072 0.5895590046648143 0.5554863428780332 1.0 0.8267526502368533 16 P04083,P02786,P04439 3 +Positive regulation of cellular protein catabolic process 0.4952799559069348 0.5872958923732824 0.5570049993786439 1.0 0.8283604854525993 48 P53350,Q9UNN5,P15311,O95816,Q96HY6,P04062,P46379,P31749,P98164,P53634,Q07954 11 +Organelle fusion 0.4863419215846624 0.5871907447877077 0.5570756075747281 1.0 0.8283604854525993 54 P04083,Q13277,O15400,P31751,Q9NQ11,Q9Y3E7,Q13190,Q5SQN1,Q86Y82,Q9Y6C9,Q9UN37,O43752,Q99536,P02786 14 +Establishment of epithelial cell polarity 0.477418019279358 0.5868626627039416 0.5572959476834678 1.0 0.8284988854577244 7 P15311,Q13308,P61586 3 +Oogenesis 0.4904844700524062 0.5820370373920282 0.5605417336185201 1.0 0.8319942284214696 15 Q9Y2W6,P07686 2 +Placenta development 0.4972093982487962 0.5794420700842338 0.5622909242158896 1.0 0.8342100995089884 21 P07858,P31749 2 +Positive regulation of defense response 0.5019414112796349 0.5787158988533505 0.5627808864132335 1.0 0.8347467693210641 38 Q08722,Q9NUD5,Q9BY67,P11279,P05067,P53634 6 +Neurotransmitter reuptake 0.4686148451285442 0.5784621836616856 0.5629521216648492 1.0 0.8348105494392183 4 P05556 1 +Negative regulation of glycogen metabolic process 0.4629684272646951 0.5759142027854531 0.5646731751488812 1.0 0.8365729874011254 2 P22413 1 +Leukocyte mediated immunity 0.4917960391922922 0.574478689298895 0.5656439174218009 1.0 0.8368958869127099 49 Q9BY67,O15400,P11279,P01889,P53634,O96028,Q07021,P02786,P04439 9 +Retina development in camera type eye 0.490179155209871 0.5741766047364764 0.5658482991593954 1.0 0.8370080498813142 16 Q15555,P54802,P23634,Q16706 4 +Protein targeting 0.2932735606041222 0.5707654290462297 0.5681586601790594 1.0 0.8390549838313133 117 Q99523,Q9H173,O60830,Q14108,O43464,P20645,P55786,Q99595,P31751,P62258,P13473,P40855,P27105,P46934,Q15041,P46379,P31946,O00560,Q9UN37,O95831 20 +Positive regulation of oxidoreductase activity 0.483174621506595 0.5704419763075307 0.5683779660357282 1.0 0.8390549838313133 12 P00374,Q8WTV0,P31749 3 +Positive regulation of epithelial cell proliferation 0.4950451538240168 0.5692608410389212 0.5691791372229436 1.0 0.8398359436358483 21 P21359,Q04656,P31749,P15291,P40763 5 +Steroid metabolic process 0.4392591793855377 0.5690700708561833 0.5693085883561348 1.0 0.8398365987306681 72 Q9UBM7,Q99538,O15118,P04062,P05067,Q8WTV0,Q15392,Q13510,P98164,P61916,Q9NWW5,P38571,P48449 13 +Regulation of cellular response to growth factor stimulus 0.4999884674196066 0.5683820319996385 0.5697755883698785 1.0 0.8399545018767911 38 P46934,P62942,P98164,O00560,Q92896,Q92859,O94813,Q05D32 8 +Regulation of body fluid levels 0.4847962698359005 0.5676508052106175 0.5702721020135928 1.0 0.840496124996262 53 Q16739,P35670,Q04656,P04062,Q93063,Q11206,P19021,Q13572,Q9BWH2,Q9Y624 10 +Deoxyribonucleoside monophosphate metabolic process 0.4729464030433001 0.5673507757074883 0.5704758860697243 1.0 0.8406061607772534 7 O43598,P34896 2 +Positive regulation of g protein coupled receptor signaling pathway 0.4631050767414467 0.5655329942739215 0.5717112889235043 1.0 0.8418548950219437 3 O14744,P35232 2 +Establishment of mitotic spindle localization 0.4800677721277929 0.5644047232586616 0.5724787251400356 1.0 0.8423981586224414 11 P53350,P05556,O14777,Q14203 4 +Positive regulation of axon extension 0.4818196028745868 0.56440201959841 0.5724805647242364 1.0 0.8423981586224414 12 P46821,Q7L576,Q9UJU6,P43034,A0MZ66,Q7L099 6 +Regulation of wound healing 0.4833171618688294 0.5636161118455455 0.5730154193270254 1.0 0.84282204695412 13 P04083,P05556,Q11206 3 +Cellular response to reactive oxygen species 0.4991869130418248 0.5634152013467872 0.5731521883073791 1.0 0.8428327865102865 29 P00374,P04083,O15111,P09493,Q04656,P31749,O95831,Q99720 8 +Regulation of vacuole organization 0.4875265106878395 0.5620872161815621 0.5740565978528904 1.0 0.8436905620234879 16 Q9NUM4,Q14108,Q8TBX8 3 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.4717109460559601 0.5619878467041035 0.5741242995029265 1.0 0.8436905620234879 7 Q92783,Q9H3S7,Q9BRG1 3 +Tumor necrosis factor superfamily cytokine production 0.4888179373141328 0.5617840329629131 0.574263172147198 1.0 0.8437041865669733 17 Q08722,P05067 2 +G protein coupled receptor signaling pathway 0.4920211986431533 0.5558141646810396 0.5783379012778458 1.0 0.8474287685413638 46 P04083,Q99523,P07602,Q9BYT8,P31749,P42892,Q9UBI6,Q06481,Q86V85,P11717,Q99720 11 +Regulation of carbohydrate metabolic process 0.4979182329151108 0.5544388591953973 0.5792785380165109 1.0 0.8483921895359924 36 P31751,Q9BYT8,Q14108,P05067,P31749,Q92520 6 +Response to reactive oxygen species 0.497854428721705 0.5528463937343561 0.5803685971164234 1.0 0.8496063789583802 33 P00374,P04083,O15111,P09493,Q04656,P31749,O95831,P17655,Q99720 9 +Dna topological change 0.4693578465221838 0.5518079835419326 0.5810799169151286 1.0 0.8502957661547879 7 Q13472 1 +Adherens junction assembly 0.4617655742545039 0.5491617558964191 0.5828944473921913 1.0 0.8521633078788251 4 Q9BTW9,P35222,Q13177 3 +Dendrite development 0.4797282934689509 0.5470049268487019 0.5843753472970579 1.0 0.8537440554093013 54 P39880,P05556,Q9UQ16,P46934,Q7L576,P05067,Q13641,Q9UJU6,P61586,Q14444,Q04917,P43034,Q9NUM4,Q9UQB8,Q9UL25,Q86X55,P61160 17 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.4721532719881344 0.5461867587422725 0.5849375671353179 1.0 0.8541820462204843 9 Q92896 1 +Regulation of small gtpase mediated signal transduction 0.4960468072990235 0.5436420883737451 0.5866877910194965 1.0 0.8561472149511314 34 P21359,Q15555,P05556,Q9H3F6,P41440,Q9Y5K6,P06756,P52565,O75955,Q68EM7,Q9Y624,O94813 12 +Pyrimidine ribonucleotide biosynthetic process 0.4731232664523608 0.5419857507446374 0.5878283220938041 1.0 0.8572496363867976 10 P15531,P17812,O75414,P11172 4 +Cellular glucan metabolic process 0.4856620478395042 0.5414718045857132 0.5881824266110796 1.0 0.8575739299525482 18 P31751,P31749,Q15185,P46020,P10253 5 +Gtp metabolic process 0.4808783596485061 0.5386406527101177 0.5901348311264545 1.0 0.860227888632606 15 P15531,O75414,O60313,P61586,Q7Z2Z2,Q9ULC3 6 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.4804760445364724 0.5368399050343641 0.5913782045661913 1.0 0.8616544565187791 15 Q9Y263,P46934,Q9Y3E7,Q9H3S7,Q92783,Q9BRG1,Q9UN37 7 +Adenylate cyclase inhibiting dopamine receptor signaling pathway 0.4535261138979052 0.5360335006304714 0.5919353976438919 1.0 0.8618980752525405 2 O14744 1 +Regulation of protein localization to cell periphery 0.4942877393831179 0.5349909372018092 0.5926561241513526 1.0 0.8627440447731005 35 P53350,P05556,Q13277,P15311,P31749,O00264,P23634,Q9UN37,O15400,Q13136,Q07954 11 +Regulation of podosome assembly 0.4576321228225533 0.5316701544671747 0.5949544663999742 1.0 0.8647362304674775 4 Q16658,P26038,P61586 3 +Positive regulation of podosome assembly 0.4576321228225533 0.5316701544671747 0.5949544663999742 1.0 0.8647362304674775 4 Q16658,P26038,P61586 3 +Regulation of superoxide anion generation 0.457430221068987 0.5308195989451778 0.595543797259867 1.0 0.8648692992755107 4 Q9NY61,Q05655 2 +Protein refolding 0.4741355987365858 0.5304378685375121 0.5958083762475286 1.0 0.8648692992755107 12 P48723,P62942 2 +Glial cell proliferation 0.4596866648717595 0.52992611623425 0.5961631580261204 1.0 0.8648692992755107 5 Q96G23,P04062 2 +Progesterone receptor signaling pathway 0.4571911321638785 0.5298128542075136 0.5962416920350986 1.0 0.8648692992755107 4 P46934 1 +Mitotic intra s dna damage checkpoint signaling 0.4617986619255699 0.5287444133704503 0.5969827629928517 1.0 0.8657513448615426 6 O60921 1 +Respiratory chain complex iv assembly 0.4638727171527798 0.5282607771432626 0.5973183509774285 1.0 0.8660140306267797 7 Q15070 1 +Sphingolipid biosynthetic process 0.4839652142416986 0.5280999641936555 0.5974299556904559 1.0 0.8660140306267797 19 O60512,Q16739,P04062,Q13510,Q99805 5 +Negative regulation of growth 0.4927003402444605 0.5268734857762736 0.5982814473850713 1.0 0.867055258788249 33 Q99538,Q15375,P50897,O94813 4 +Positive regulation of cell cycle phase transition 0.4845732047002448 0.5259803711454722 0.59890184519824 1.0 0.8672362212798032 48 Q13619,P04083,Q9UJX5,Q96HY6,Q9UJX4,P05067,Q13620,P06493,P31749,Q96ST3,Q9H4H8,Q9UHI8,Q9P258,Q96DY7 14 +Vesicle docking 0.4822283511411961 0.525857742826869 0.598987051142541 1.0 0.8672362212798032 18 Q13277,O15400,P56545,Q13190,Q86Y82,O43752 6 +Regulation of adaptive immune response 0.4856291135739877 0.525413184337809 0.5992959901749599 1.0 0.8672362212798032 21 P04083,P01889,O15400,P02786,P04439 5 +Response to prostaglandin 0.4609994280468693 0.5253515519429076 0.5993388263498978 1.0 0.8672362212798032 6 P31749 1 +Regulation of cell cell adhesion 0.4800646567857367 0.5218277367773673 0.6017902758210072 1.0 0.8693311781086511 51 Q9NUQ9,Q15375,Q08722,P04083,P41440,Q16539,P30825,Q14254,P10644,O75955,Q9H3S7,P31749,P61586,Q11206,Q5JRA6,Q9Y624,P02786,P04439 18 +Positive regulation of chromosome condensation 0.4577672770230415 0.5218230187799707 0.6017935610692382 1.0 0.8693311781086511 5 Q15021,Q9NTJ3,O95347,Q15003 4 +Negative regulation of cell differentiation 0.3975659391534346 0.5217348824034678 0.6018549339071722 1.0 0.8693311781086511 82 Q96AC1,Q15375,P05556,Q99523,P05067,Q9UBS4,Q06481,Q9P258,Q13619,P21359,P11413,P04083,Q9UPY3,Q8N4Q0,P67809,Q96G23,P06756,Q04917,P40763,Q8N5W9 20 +Protein processing involved in protein targeting to mitochondrion 0.4526214926515595 0.5213191437140876 0.6021444672145542 1.0 0.8695564511017629 3 Q10713 1 +Potassium ion import across plasma membrane 0.4595814059166943 0.5193460166335706 0.6035194691886436 1.0 0.870769446901168 6 P54709,P05026 2 +Membrane organization 0.2846270944728539 0.5184715799469609 0.6041292840138879 1.0 0.8710857183383103 249 Q13277,O15118,Q9UH99,Q15392,Q13190,Q5SQN1,Q06481,P08183,O43752,Q08431,O15027,Q9Y6B6,Q9Y3E7,Q9NQX3,P50897,Q8NB49,Q15070,P04083,P53350,P04114,P31751,P51790,Q9NV96,Q5XKP0,Q9H3K2,P61916,Q86Y82,Q5JRA6,O15400,Q6NUK4,Q14203,Q9NQ11,Q16739,P19022,Q15041,O75955,P31749,Q9P0I2,O14657,P46379,Q96GC9,Q9UQB8,Q9UN37 43 +Response to insulin 0.4521523393391912 0.5184560812739674 0.6041400949765701 1.0 0.8710857183383103 65 Q99523,P31751,Q8TBX8,P31749,Q06481,Q9UQB8,P08069,Q92572 8 +Metal ion export 0.4694460247192933 0.5178390001769899 0.6045706050192767 1.0 0.8713490626254871 11 P62258,P54709,P35670,Q04656,P05026,P23634 6 +Presynaptic modulation of chemical synaptic transmission 0.4488049572145203 0.5163837339964137 0.6055864241634352 1.0 0.8720123028763582 2 P35268 1 +Positive regulation of voltage gated calcium channel activity 0.4488049572145177 0.5163837339964022 0.6055864241634432 1.0 0.8720123028763582 2 O75323 1 +Positive regulation of neurotransmitter secretion 0.4488049572145177 0.5163837339964022 0.6055864241634432 1.0 0.8720123028763582 2 Q15042 1 +Negative regulation of cell size 0.4532808683108879 0.5134211460892895 0.6076567568169318 1.0 0.8734770984923161 4 P35241,P61586 2 +Regulation of epithelial cell migration 0.4880393211202376 0.5125168362870229 0.608289340193511 1.0 0.8735409177688916 41 P21359,P04083,Q99538,Q8WTV0,P31749,Q13685,P42785,O94813 8 +Regulation of organelle organization 0.2821440913843872 0.5124032022855747 0.6083688502715412 1.0 0.8735409177688916 348 Q08722,Q96AC1,O75414,Q8TD16,O60313,Q7L576,Q9UJU6,Q13190,Q8NEY8,Q96ST3,O15511,Q13576,Q9Y624,Q99536,P02786,Q07954,Q9Y6B6,P15311,Q9Y5K6,Q9Y3E7,Q9UJX4,Q14108,Q8TBX8,O43464,Q9P2S5,P19784,P61586,Q92783,O43293,P19021,O94813,Q96DY7,Q96HS1,P04083,Q15555,P53350,P31751,Q9H3K2,O14777,O15260,Q16181,Q14203,P58546,Q9NQ11,Q9UJX5,P09493,P19022,Q15041,P11234,P31749,Q9NUM4,O00560,O60934,Q9UQB8,P17655,Q6UWE0,Q9Y3P9,Q9Y6C9 58 +T cell lineage commitment 0.4553362059520928 0.5116079417983993 0.6089254261399644 1.0 0.8737828059853305 5 P40763 1 +Positive regulation of protein binding 0.4843609370491576 0.5104901338927664 0.6097081248781291 1.0 0.8745981094697279 23 P41440,P05067,P62942,O75955,Q96D46,Q07954 6 +Regulation of stress activated protein kinase signaling cascade 0.4879551122778299 0.5085093709636116 0.6110961689528462 1.0 0.875684802967869 29 P15311,Q96KB5,P05067,O75915,O43567,O00560,P08069,O75844 8 +Multicellular organismal homeostasis 0.4478538161712408 0.5066747382376933 0.6123830583782919 1.0 0.8768631610872439 66 P05556,Q9UIQ6,P04062,Q96N67,Q9H9B1,Q06481,O14773,P08069,P38571,Q9Y624,P02786,P21359,Q9C0B1,P78310,Q96HS1,P51790,P42785,Q9UDY2,Q9UBB6,Q16739,Q93063,P40763 22 +Regulation of glial cell apoptotic process 0.4489374262101548 0.5060150856561119 0.6128460594430745 1.0 0.8768631610872439 3 Q02952,Q05655 2 +Positive regulation of protein catabolic process 0.4451216337250389 0.5059933056775892 0.6128613491469985 1.0 0.8768631610872439 67 P53350,Q9UNN5,P15311,O95816,Q96HY6,P46934,P04062,Q13620,Q13190,P98164,P46379,P31749,P53634,Q07954 14 +Columnar cuboidal epithelial cell differentiation 0.4622731951268283 0.5036487993353282 0.6145081939125081 1.0 0.8786400927675 9 P31749 1 +Positive regulation of protein localization to membrane 0.4878541197373245 0.5034418291320487 0.6146536689548605 1.0 0.8786551130645899 32 P05556,Q13277,P31751,P31749,O00264,P27105,P23634,Q07954 8 +Protein k11 linked ubiquitination 0.4619187582932187 0.5021393877202531 0.6155694755373131 1.0 0.879771083589003 9 Q9UJX4,Q9UJX5,Q9H1A4 3 +Regulation of genetic imprinting 0.4449690174092706 0.5005704928012905 0.6166734332912549 1.0 0.8807700163637139 2 Q6PD62 1 +Genomic imprinting 0.4449690174092706 0.5005704928012905 0.6166734332912549 1.0 0.8807700163637139 2 Q6PD62 1 +Membrane disassembly 0.4526267941661323 0.5002884098794882 0.6168720138595993 1.0 0.8807700163637139 5 P53350,Q14203 2 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4653133671937818 0.499992737531206 0.6170801911881565 1.0 0.8807700163637139 11 P21359,O43464,P31749 3 +Angiotensin activated signaling pathway 0.4470530512249359 0.4982368141328683 0.6183171374406835 1.0 0.8822215725750601 3 Q13464 1 +Regulation of establishment or maintenance of cell polarity 0.460984000601864 0.4981643489502042 0.6183682082427033 1.0 0.8822215725750601 9 Q9NUQ9,Q15334,Q14254,Q13464,A0MZ66,O75116 6 +Positive regulation of epithelial cell migration 0.4832312550130966 0.4974131554271987 0.6188977304553684 1.0 0.882783572582044 25 P04083,Q99538,Q8WTV0,P31749,Q13685 5 +Corpus callosum development 0.4490699734278099 0.4959287364096369 0.619944690768309 1.0 0.8834414321718944 4 P43034,Q99622,Q96P11 3 +Deoxyribonucleotide biosynthetic process 0.4562050557590986 0.4957972490133957 0.6200374659897674 1.0 0.8834414321718944 7 P55263,Q7LG56,P34896 3 +Negative regulation of response to cytokine stimulus 0.4582619443738169 0.4954063635308346 0.6203133037040283 1.0 0.8836410518847317 8 O94813 1 +Regulation of chromosome condensation 0.4581732190363525 0.4950320669962357 0.6205774850975514 1.0 0.8838239833701728 8 Q7Z5K2,Q15021,Q15003,O60264,O95347,Q9NTJ3,Q9UIG0 7 +Regulation of cell morphogenesis 0.4459729834447457 0.4938884914659973 0.621384932716974 1.0 0.8846701115790564 66 Q96AC1,Q15334,Q7L576,Q9UJU6,Q9Y624,Q9P258,P15311,P61586,Q14444,O43293,Q07021,P04083,P35580,Q9Y263,P07686,Q16181,P61160,P39880,P09493,P43034,Q9UQB8,Q9UL25,O75844 23 +Scarna localization to cajal body 0.4509746012994714 0.493420288287871 0.6217156499254419 1.0 0.8847697183171123 5 P78371,P50991,Q9BUR4,O60832 4 +Rab protein signal transduction 0.450950881755981 0.4933218800434359 0.6217851707067263 1.0 0.8847697183171123 5 P20338,Q9UL25 2 +Mitochondrial protein catabolic process 0.4429035113602956 0.4921143308967362 0.622638521851627 1.0 0.8854034026330476 2 Q96TA2 1 +Muscle organ development 0.4838750915800762 0.4904642485078379 0.6238054224790723 1.0 0.8857084624512019 41 P21359,P41440,P60660,P58546,Q16539,Q9BYT8,P09493,P62942,O75955,P61586,P98164,P14649 12 +Regulation of cyclase activity 0.4546730058785872 0.4893775917806182 0.6245743974295983 1.0 0.8859976606462872 7 P21359 1 +Regulation of protein localization to nucleus 0.4700723630243296 0.489109019079094 0.6247645165424709 1.0 0.8859976606462872 54 P21359,Q96AC1,P53350,O95071,Q16539,Q9NQ11,P31749,P06493,O95251,Q96ST3,Q96D46,O00410,Q9ULC3,P02786 14 +Attachment of mitotic spindle microtubules to kinetochore 0.4556650420264972 0.4844828965974154 0.6280431996656091 1.0 0.8890109219010905 8 O14777 1 +Establishment of endothelial barrier 0.47157615430869 0.4842394991899756 0.628215907489849 1.0 0.8890620777736776 17 P15311,Q9UDY2,Q13464,Q9Y4G8,Q9Y624 5 +Peptidyl proline hydroxylation 0.4528878804646694 0.4819266453006349 0.6298580570008085 1.0 0.8907628595374344 7 P13674,O15460 2 +Non motile cilium assembly 0.4695540861139962 0.481776101038127 0.6299650084962132 1.0 0.8907628595374344 16 Q15555,Q8NCM8,Q9P2S5,Q15154,Q16181,Q14203 6 +Positive regulation of immunoglobulin production 0.4640525147301139 0.4790326435857088 0.6319154059895697 1.0 0.8919707920624672 13 P02786 1 +Limbic system development 0.4758775550265164 0.4759763153297461 0.6340912515710255 1.0 0.8941416356612796 22 P21359,Q13144,P62258,O14949,P23634,O15511,P08069 7 +Actin filament organization 0.2845123013841922 0.4758916630547222 0.6341515619402744 1.0 0.8941416356612796 112 Q08722,Q96AC1,Q9NUQ9,P05556,Q7L576,Q9UJU6,Q14019,Q9Y3C0,P57737,O15511,Q13576,Q9Y624,P15311,Q9Y5K6,P67936,Q13464,P61586,P12814,O94813,A0MZ66,Q68EM7,Q13136,P61160,P58546,P09493,Q9UQB8,Q8N5W9 27 +Negative regulation of necrotic cell death 0.4440985176914628 0.475499863347297 0.6344307306159926 1.0 0.8941416356612796 4 P16989,P12235 2 +Negative regulation of programmed necrotic cell death 0.4440985176914628 0.475499863347297 0.6344307306159926 1.0 0.8941416356612796 4 P16989,P12235 2 +Embryonic camera type eye development 0.4387724992623207 0.4753295100256611 0.6345521285338114 1.0 0.8941416356612796 2 O94788 1 +Brown fat cell differentiation 0.4487566276364025 0.4741275824495315 0.6354089305436641 1.0 0.8945636750764409 6 Q16539 1 +Energy reserve metabolic process 0.4731698963710256 0.473848888118939 0.6356076694258341 1.0 0.8945636750764409 20 P31751,P31749,Q15185,P46020,P10253 5 +Monosaccharide metabolic process 0.4134959569222403 0.4735085347653822 0.6358504133884031 1.0 0.8945636750764409 76 P04066,P31751,Q9UBX3,Q8NBZ7,Q9BYT8,O00754,P16278,Q16706,Q9BTY2,P15291,P31749,Q92520,P10253 13 +Positive regulation of cell development 0.4565301226547752 0.4725577608628593 0.6365287236022503 1.0 0.8946031931456498 60 P39880,Q96AC1,Q9UPY3,Q9UJU6,Q16706,P98164,Q14444,Q07021,A0MZ66,Q9UQB8,P61160,P55209,Q9Y624,O94813 14 +Mitotic chromosome condensation 0.4585798816568171 0.4712674742301209 0.6374497396890146 1.0 0.8949925337091122 11 P53350,Q15021,Q15003,O60264,O43823,O95347,Q9ULX6,Q9NTJ3,Q9UIG0,P42695 10 +Positive regulation of smad protein signal transduction 0.4375922100914895 0.4705658580176578 0.6379507937126159 1.0 0.8952095089424019 2 Q8N1F7 1 +Negative regulation of actin filament bundle assembly 0.4564580813367022 0.4705380245698134 0.6379706741765951 1.0 0.8952095089424019 10 Q13136,Q9Y624 2 +Axo dendritic transport 0.4796302308589886 0.4664257296927976 0.6409107980071418 1.0 0.8981540161039925 30 Q9Y496,Q14254,O60313,Q96BM9,P05067,P43034,O60333,Q14168,Q9UL25,Q92572,Q14203 11 +Insulin receptor signaling pathway 0.4802892729342788 0.4663977774615061 0.6409308020763516 1.0 0.8981540161039925 32 P31751,Q8TBX8,P31749,Q9UQB8,Q92572 5 +Sensory perception 0.4806675891654231 0.4663196412613166 0.6409867217848155 1.0 0.8981540161039925 35 P98164,Q14108,P50897,P07686 4 +Glycerophospholipid catabolic process 0.4532347938316737 0.4655419359327143 0.6415434129222093 1.0 0.8987406107431853 9 Q8NCC3 1 +Endocytic recycling 0.4762716493410371 0.4650674822504802 0.641883131785641 1.0 0.8990230610853105 25 Q9H4M9,Q9H3S7,P42566,Q9H223,O75436,O43752,Q15904,Q96C92,P51149 9 +Cellular response to hydrogen peroxide 0.4653574182436502 0.4634641266414467 0.643031722681888 1.0 0.9003818017630998 16 P04083,O95831,Q99720 3 +Proteasomal protein catabolic process 0.2914508557506673 0.4631659806520087 0.6432453988186237 1.0 0.9003818017630998 158 Q9BZK7,O95816,P04062,Q9H1A4,Q99436,Q9BUN8,Q13619,Q96HY6,Q9Y5K6,P28070,Q9UJX4,Q13620,Q9Y4X5,Q9H1I8,Q8IXB1,P53350,Q9H3F6,O94822,Q96KB5,Q9Y297,Q9Y263,P49721,Q9NWU2,P49720,P20618,P60604,Q7L5Y9,Q9UNN5,Q9UJX5,P46934,Q9GZU8,P31749,Q9GZP4,P46379,O00560,Q13616,P28074,P28072 38 +Fertilization 0.4789418243757989 0.46313421578102 0.6432681658986448 1.0 0.9003818017630998 30 P04114,P07686,Q9GZP4,P15291,Q08431,Q9Y2W6 6 +Single strand break repair 0.4377213695395332 0.4602392516507797 0.645344499762778 1.0 0.902124263142728 3 Q15554,P18887 2 +Negative regulation of multicellular organismal process 0.286533834986822 0.4598718123787184 0.6456082337986762 1.0 0.902293204352232 121 Q15375,Q9UIQ6,P04062,Q96N67,Q9UBS4,Q06481,P23634,Q13619,P49591,P21359,P15311,Q9Y5K6,Q99538,Q9H3S7,P61586,P53634,P11413,Q07021,O94813,Q9Y6I3,Q96HS1,P04083,Q9UPY3,Q9UHI8,Q96G23,Q04917,Q8N5W9 27 +T cell activation 0.4523356561708641 0.459117311717754 0.6461499255724505 1.0 0.902293204352232 61 Q08722,P04083,Q9BY67,Q04656,P04062,P62942,P10644,P31749,P40763,P78310,Q92542,P02786,P04439 13 +Positive regulation of myeloid cell differentiation 0.4672581959681812 0.4590696109385026 0.6461841785322484 1.0 0.902293204352232 18 P36896,P40763,Q9GZP4,O95251 4 +Negative regulation of adenylate cyclase activity 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 0.902293204352232 2 P08754 1 +Negative regulation of lyase activity 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 0.902293204352232 2 P08754 1 +Amyloid precursor protein catabolic process 0.4670844083886671 0.4583074390245983 0.6467315803875002 1.0 0.9023194574201944 18 P62942,Q92542,Q15392 3 +Fatty acid derivative metabolic process 0.4707473164051289 0.457768701206012 0.6471186243294258 1.0 0.90247263161623 21 Q9UMR5,P19021 2 +Sensory perception of light stimulus 0.463992508276737 0.4575476040876621 0.6472774941626451 1.0 0.9025008539299252 16 P50897 1 +Stress activated protein kinase signaling cascade 0.4785900827098182 0.4560780368044853 0.6483338632005606 1.0 0.903758151182951 36 P15311,Q16539,Q96KB5,P05067,O75915,P61586,O95251,O43567,O00560,P08069,O75844 11 +Regulation of cell cell adhesion mediated by cadherin 0.4417836580103044 0.4557139189739473 0.6485957115709289 1.0 0.903758151182951 5 O75955 1 +Positive regulation of cell cell adhesion mediated by cadherin 0.4417836580103044 0.4557139189739473 0.6485957115709289 1.0 0.903758151182951 5 O75955 1 +Jnk cascade 0.4633922098389428 0.4549516961255457 0.6491439902029112 1.0 0.9041350826317828 16 O00560,P05067 2 +Protein import into peroxisome membrane 0.4387318322178291 0.4537316697174562 0.6500219696628255 1.0 0.9046900297904168 4 P40855 1 +Polarized epithelial cell differentiation 0.4459424923046378 0.4532465931822819 0.6503711851335667 1.0 0.9048763443512544 7 P15311,Q13308,P61586 3 +Regulation of autophagy 0.2963990773522459 0.452737219576122 0.6507379751612818 1.0 0.9051932090384498 102 Q9NQ11,P10619,P07602,P61421,Q9Y487,O15118,P04062,Q8TBX8,P31749,P68402,O43293,P40763,Q6UWE0,P07384,Q93050 15 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.4408616109399208 0.4519798580176772 0.6512834928678519 1.0 0.9055650445471414 5 O15460 1 +Endocrine system development 0.4558128563906293 0.4516375762427823 0.6515300952833958 1.0 0.905612704440152 12 P21359,P04083,P31749 3 +Regulation of ubiquitin protein ligase activity 0.4591731892782985 0.4507784388780851 0.6521492425230415 1.0 0.9057504109683076 14 P53350,P60866,O95816,Q9Y297 4 +Developmental cell growth 0.4757936994109883 0.4507315893769782 0.6521830120547021 1.0 0.9057504109683076 42 Q15375,P05556,Q99829,Q9Y263,Q7L576,P05067,Q9UJU6,P43034,A0MZ66,Q96ST3,P11413,O94813 12 +Neural tube development 0.4751211623648881 0.449879183819829 0.6527975579246799 1.0 0.9059288215923398 28 P98164,Q13572,P21359 3 +Ras protein signal transduction 0.4368275681785612 0.4492902366998503 0.6532222998841197 1.0 0.906235437664804 67 P05556,Q7L576,Q9UJU6,Q15392,Q9Y4G8,Q9Y624,P26358,P21359,Q13464,P61586,Q14974,P20338,Q15555,Q9H3F6,P60953,P40818,A0MZ66,Q68EM7,P41440,P52565,P11234,O75955,P11233,O00560,Q9UL25,Q96RT1 26 +Regulation of developmental growth 0.4633105986268029 0.4491867931287285 0.6532969138188824 1.0 0.906235437664804 54 Q15375,Q7L576,P05067,Q9UJU6,Q96ST3,P15311,Q16539,Q9C0B1,Q99538,O43464,P16989,P11413,Q9Y263,P06493,A0MZ66,P43034,P31749,P40763,O75844 19 +Phosphatidylcholine metabolic process 0.4548488045218081 0.4475855967247328 0.6544522999195692 1.0 0.907258192605706 12 Q8NCC3,Q8WTV0,P17655 3 +Ear development 0.4689235996801323 0.444638374748784 0.6565811105390595 1.0 0.90944511094464 22 P42892 1 +Meiosis ii cell cycle process 0.4308055473591023 0.4434622132136278 0.6574314449937002 1.0 0.9096447836150884 2 O60566 1 +Meiotic sister chromatid cohesion centromeric 0.4308055473591023 0.4434622132136278 0.6574314449937002 1.0 0.9096447836150884 2 O60566 1 +Negative regulation of receptor signaling pathway via jak stat 0.4308055473591022 0.4434622132136271 0.6574314449937007 1.0 0.9096447836150884 2 O14964 1 +Negative regulation of receptor signaling pathway via stat 0.4308055473591022 0.4434622132136271 0.6574314449937007 1.0 0.9096447836150884 2 O14964 1 +Regulation of nuclease activity 0.4515537381995979 0.4417896173775448 0.6586414524425401 1.0 0.9103879685125272 11 P26583,P31749 2 +Regulation of post translational protein modification 0.4330918885793272 0.441728129754866 0.6586859515482848 1.0 0.9103879685125272 3 Q32P28 1 +Positive regulation of b cell activation 0.4534265744162138 0.4416262979964092 0.6587596507001332 1.0 0.9103879685125272 12 P02786 1 +Negative regulation of gliogenesis 0.4407237530806531 0.4413398978228058 0.6589669461403163 1.0 0.9104148597991212 6 Q96G23,P21359 2 +Hippocampus development 0.4601547283062278 0.4410184358149374 0.6591996504244033 1.0 0.9104297878680028 16 Q13144,P62258,O14949,P23634,P08069 5 +Cell junction assembly 0.4246663849605901 0.4406701007915428 0.6594518451567248 1.0 0.9104297878680028 71 Q96AC1,Q15375,P23229,P41440,Q9UQ16,P19022,P05067,Q13641,Q9UJU6,P61586,O75955,Q96GC9,O43293,O00560,O00192,Q9Y624,Q9P258 17 +Sterol metabolic process 0.4742802142489845 0.4403559824571905 0.6596793001870678 1.0 0.9104297878680028 41 Q9UBM7,O15118,P04062,P05067,Q8WTV0,Q15392,P61916,Q9NWW5,P38571,P48449 10 +Positive regulation of cell morphogenesis involved in differentiation 0.4697934400714644 0.4394793961928595 0.6603142080898916 1.0 0.9107144746753508 24 P39880,Q96AC1,Q9UJU6,P43034,Q14444,Q9UQB8,P61160,Q07021 8 +Gland development 0.4244854103528416 0.4393832283138356 0.6603838769962862 1.0 0.9107144746753508 71 P21359,P04083,Q9BY67,P31751,P07602,P35670,Q04656,P31749,Q16706,P19021,P11717 11 +Positive regulation of cytokine production 0.4547459033230407 0.4376615927367115 0.6616316150452597 1.0 0.9119673542122888 58 P04083,Q9BY67,O15111,Q9NUD5,Q16539,P41440,P05067,O75955,O75787,P40763,P04439 11 +Positive regulation of catabolic process 0.2894881352621317 0.4320110001043336 0.6657334183052446 1.0 0.9158758565441972 156 O95816,P04062,P05067,Q13190,P98164,Q07954,P15311,Q96HY6,Q9C0B1,Q9H074,Q8TBX8,Q13620,P68402,Q14671,P53634,Q5PRF9,P53350,P31751,P67809,Q7Z739,Q9UNN5,P46934,P11234,P31749,P46379,Q6UWE0 26 +Positive regulation of protein phosphorylation 0.2945069289615383 0.4296966764028681 0.6674163014126635 1.0 0.917239558137494 102 Q96AC1,Q15375,P53350,P41440,P31751,Q96HY6,Q96N67,P05067,O75955,P31749,P11234,Q9H223,Q8NDZ4,O00560,O60934,P23634,P02786 17 +Pattern recognition receptor signaling pathway 0.4726648662739284 0.4296790114100783 0.6674291531332273 1.0 0.917239558137494 32 Q9NUD5,Q5KU26,O75955,Q9Y4E8,Q06481,Q14671,Q07021,Q9NPR9 8 +Process utilizing autophagic mechanism 0.2883959165830475 0.4262707583387388 0.6699105629302196 1.0 0.9188327987255748 169 P07602,O15118,P04062,P07384,O15027,Q9Y3E7,Q8TBX8,O43464,P19784,P68402,Q92783,O43293,Q93050,Q96HS1,P10619,P61421,P13473,Q9Y487,Q86Y82,Q9ULC3,Q9BWH2,Q9NQ11,P46934,P11234,P31749,Q9GZZ9,Q96GC9,P40763,Q9BRG1,Q9UN37,Q6UWE0 31 +Regulation of p38mapk cascade 0.4291499392798556 0.4261542123848274 0.6699954792038523 1.0 0.9188327987255748 3 P15311 1 +Retrograde transport endosome to golgi 0.4722014096689901 0.4261481563538951 0.6699998917896011 1.0 0.9188327987255748 33 Q9C0C9,Q13190,O75503,Q8NBN3,O15260,O43752,Q4J6C6 7 +Neuroblast proliferation 0.4476486252904879 0.4256384154274301 0.6703713434376306 1.0 0.918906718610892 11 P21359,Q96N67,P43034 3 +Regulation of erythrocyte differentiation 0.4547939632365108 0.4250857380883402 0.6707741742068984 1.0 0.918906718610892 15 P40763,P36896,Q16539,O95251 4 +Positive regulation of amino acid transport 0.4341187955612759 0.424958289292733 0.6708670814371942 1.0 0.918906718610892 5 Q15041 1 +Positive regulation of amine transport 0.4341187955612759 0.424958289292733 0.6708670814371942 1.0 0.918906718610892 5 Q15041 1 +Regulation of cardiac muscle cell action potential 0.4389465726986588 0.4248824346580039 0.6709223801038955 1.0 0.918906718610892 7 P78310 1 +Axon extension 0.4680498033971018 0.4237211274067676 0.6717692052132636 1.0 0.918906718610892 26 P05556,Q7L576,Q9UJU6,P43034,A0MZ66,Q96ST3,O94813 7 +Regulation of protein localization to membrane 0.4662099208853644 0.4235563556802963 0.6718893905224448 1.0 0.918906718610892 48 P05556,Q13277,P15311,P31751,Q15334,P19022,P31749,O00264,P27105,P23634,Q9UN37,O15400,Q13136,Q07954 14 +Escrt complex disassembly 0.4385945699358738 0.4234698496321926 0.6719524918182329 1.0 0.918906718610892 7 Q9UN37 1 +Membrane lipid biosynthetic process 0.4687195666402401 0.4233073741816748 0.6720710147672868 1.0 0.918906718610892 27 Q96G23,Q9H490,O60512,Q16739,P04062,Q13510,Q11206,Q99805 8 +Canonical wnt signaling pathway 0.4704675233151854 0.4230072197858124 0.6722899934947923 1.0 0.918906718610892 42 Q16539,O95071,Q9BZK7,Q93074,P19022,Q9NWU2,Q99471,Q13641,O75787,O43293 10 +Regulation of heart growth 0.4428405989563009 0.4227754262033095 0.6724591183710815 1.0 0.918906718610892 9 P11413,Q16539 2 +Dendrite extension 0.4308334498817988 0.4222655285728339 0.6728312162155907 1.0 0.918906718610892 4 Q7L576 1 +Endosome to lysosome transport 0.4580076971280139 0.4189582768582449 0.6752466252197804 1.0 0.9209837691558288 18 Q99523,P20645 2 +Regulation of nucleotide metabolic process 0.4564625760046678 0.4186742420155281 0.6754542229112741 1.0 0.9210739403335556 17 P05067 1 +Phosphatidylinositol phosphate biosynthetic process 0.4493503151894184 0.4169507646085655 0.6767144209715559 1.0 0.922484618320472 13 Q9NX62 1 +Response to arsenite ion 0.4240188846267489 0.4168718761624954 0.6767721255143739 1.0 0.922484618320472 2 P55072 1 +Response to wounding 0.3609254670480704 0.4157630570065553 0.6775833942747982 1.0 0.9228175516169324 88 P05556,Q04656,P08069,Q9Y624,P10586,P21359,Q16539,Q8WTV0,P04083,P43121,P15291,Q5JRA6,P42785,Q11206,P00374,Q96G23,P09493,Q13572,Q9BWH2 19 +Developmental growth involved in morphogenesis 0.4692776344631881 0.4146529722204969 0.6783959637612937 1.0 0.9231516981785164 41 Q15375,P05556,Q99829,Q9Y263,Q93074,Q7L576,P05067,Q9UJU6,P43034,A0MZ66,Q96ST3,Q9UL25,O94813 13 +Positive regulation of nervous system process 0.4286990320244918 0.4138848315147778 0.6789584531067008 1.0 0.9236559608285614 4 P04062 1 +Centromeric sister chromatid cohesion 0.4311872415829924 0.4133720331438411 0.6793340615126193 1.0 0.9236559608285614 5 P41227,O60566,Q9GZZ1,P35222 4 +Regulation of cell morphogenesis involved in differentiation 0.4663292279528079 0.4123982049036244 0.6800475786798141 1.0 0.9242400286441732 27 P39880,Q96AC1,P60953,Q9UL25,Q9UJU6,P43034,Q14444,Q9UQB8,P61160,Q07021,Q9P258 11 +Positive regulation of immune response 0.4147717553325351 0.411908445584056 0.6804065302736135 1.0 0.9245348595452356 73 Q08722,P04083,Q9BY67,P11279,Q06481,P01889,O15400,Q07021,P02786,P04439 10 +Response to increased oxygen levels 0.4400345356862759 0.4114384994096915 0.6807510286168472 1.0 0.9246935286654864 9 Q15904,P61421 2 +Negative regulation of epithelial cell migration 0.4497834810202166 0.4112922589066858 0.6808582451491856 1.0 0.9246935286654864 14 P67870,P35080,Q9H3S7,P61586,P14923,P23634,O94813 7 +Regulation of cell size 0.4693766062279124 0.411167894810707 0.6809494280218651 1.0 0.9246935286654864 38 Q15375,P15311,P58546,P51790,Q7L576,Q04656,Q9UJU6,P43034,P61586,A0MZ66,Q96ST3,P51797 12 +Positive regulation of cell adhesion 0.4442906621405631 0.4085514544414703 0.6828688626724913 1.0 0.9262644913367116 61 Q9NUQ9,Q96AC1,Q08722,Q13277,P30825,Q14254,P23396,Q9Y624,P02786,Q9H3S7,Q13464,P61586,Q07021,P04083,P60953,Q11206,P04439,P41440,P06756,P09493,O75955,P31749,P14923 23 +Protein deneddylation 0.4388397085734152 0.4066393805230795 0.6842728692385611 1.0 0.9272582157003222 9 Q9UBW8,Q9UNS2 2 +Regeneration 0.4672768786153736 0.4059771849934898 0.684759364078964 1.0 0.9275091242833368 31 P00374,P04083,Q96G23,P58546,P19784,P08069,P11717,Q7Z4V5,P10586 9 +Peptidyl tyrosine modification 0.4682115848524902 0.4052594100709857 0.6852868391308722 1.0 0.9276172032859632 35 Q15375,P05067,Q9H223,Q9H2J4,Q9BRG1 5 +Anterograde axonal transport 0.4532815234492479 0.4051991677526817 0.6853311167052052 1.0 0.9276172032859632 17 Q9Y496,Q96BM9,O60333,Q14168,Q9UL25,Q92572 6 +Ventricular system development 0.4315233644711722 0.4046688288257083 0.6857209577790426 1.0 0.9276172032859632 6 Q96N66,Q92688 2 +Positive regulation of toll like receptor signaling pathway 0.4288589719213164 0.4042426309503402 0.6860343075848372 1.0 0.9277281558739696 5 O75955 1 +Protein localization to ciliary membrane 0.4257454974904185 0.4023774020729094 0.6874062983650404 1.0 0.9290045676471692 4 Q15276,Q9UPT5,P36405 3 +Skeletal system development 0.4577478701132185 0.4013214409865513 0.6881834797323987 1.0 0.9298618624030544 52 Q16539,Q96HY6,Q93074,O43252,Q04656,Q32P28,O96028,P07686,Q9NX62,Q93063,Q9ULC3,O75844,P29992,Q8N5W9,Q92896,Q15904,Q15125 17 +Membrane protein proteolysis 0.4435618242358373 0.4009219660074402 0.6884775769732956 1.0 0.9300101517565608 12 Q8TCT8,Q92542 2 +Dendrite self avoidance 0.421782762691857 0.3975352240735259 0.6909728169007219 1.0 0.9320830994661624 3 Q8WX93,P35613 2 +Mrna 3 end processing 0.4661081211625443 0.396927244189705 0.6914211130687307 1.0 0.932433596922857 40 Q5VTR2,P05067,Q5KU26 3 +Regulation of phosphorus metabolic process 0.2797944373373506 0.3955366501350013 0.6924468791551233 1.0 0.9332562263830582 233 Q96AC1,Q15375,P04062,P05067,Q96N67,O60921,Q9H223,Q9H2J4,P23634,O00410,P08069,P02786,Q07954,P21359,Q96HY6,Q8TBX8,Q8WTV0,P61586,Q8ND04,Q8IXB1,O94813,P23229,P53350,P31751,P62258,P62942,P00403,Q8NDZ4,P41440,P10644,O75955,P11234,P31749,Q15185,P31946,O00560,O60934,P40763,P17655,Q9BRG1 40 +Long chain fatty acid transport 0.4458656661912719 0.3951194382339086 0.6927547439653574 1.0 0.9332562263830582 14 P04083,P31749 2 +Muscle cell proliferation 0.4637955534053476 0.3946923701558749 0.6930699343141531 1.0 0.9332562263830582 29 P09493,P10644,P31749,Q8NDZ4,Q9UHI8,P08069 6 +Positive regulation of mitotic cell cycle 0.461222086258658 0.3917238127136656 0.6952622933743076 1.0 0.9344933069282654 47 Q13619,P31350,P04083,Q9UJX5,Q99538,Q9UJX4,P05067,Q7LG56,Q13620,P06493,P43034,Q96ST3,P31749,Q9UHI8,Q9P258,Q96DY7 16 +Negative regulation of cell projection organization 0.464150312341794 0.3914198066721457 0.6954869542346307 1.0 0.9344933069282654 31 Q96G23,Q15375,Q9UQ16,P43034,Q04917,P61586,Q86X55,O94813 8 +Purine containing compound salvage 0.4298854816927069 0.3889878242315335 0.6972851533517299 1.0 0.9359435769731468 7 Q13126 1 +Cellular response to leucine 0.416642077308939 0.3885903158887815 0.6975792316619598 1.0 0.9361452892433229 2 Q9P2J5 1 +Sulfur compound biosynthetic process 0.459451868910598 0.3868958370260458 0.6988333232007424 1.0 0.9365010782811588 48 Q93063,Q9P2E5,Q9NRB3,Q8WUX2,P50897,Q9UMR5,O43505,Q11206,Q8NCH0 9 +Histone h3 k14 acetylation 0.4288815981321549 0.385072692582749 0.7001835591164483 1.0 0.9371289000510028 7 O95251 1 +Cellular response to estradiol stimulus 0.4263645435132985 0.3845486524059377 0.7005718432464556 1.0 0.9374558477974154 6 P08069 1 +Negative regulation of developmental growth 0.4393555580818276 0.3839179420252936 0.7010392677249455 1.0 0.9376958358104368 12 Q99538 1 +Cellular response to inorganic substance 0.463127331780904 0.3834857715805835 0.7013596180432287 1.0 0.9377957400666422 41 Q9NQ11,Q99538,Q04656,P05067,P31749,O95831,Q14168,Q92542 8 +Phototransduction 0.4233320198872865 0.3828364238385021 0.7018410528395822 1.0 0.9379476789618888 5 Q15555 1 +Regulation of intracellular protein transport 0.4046612016675389 0.3826739489507748 0.7019615325466684 1.0 0.9379476789618888 75 Q15154,O00410,P46060,P21359,Q9Y6B6,P68036,O95071,Q16539,O43464,P19784,Q92544,P55786,P60953,P31751,Q9Y282,Q9NV96,P62258,P06493,P27105,P60604,Q9ULC3,Q9NQ11,O15078,Q92688,Q05D32 25 +Positive regulation of glial cell differentiation 0.4258339252393357 0.3824979915464757 0.7020920183688608 1.0 0.9379476789618888 6 O14744,Q9UPY3 2 +Collagen fibril organization 0.432678737197733 0.3821688832205879 0.7023361008411626 1.0 0.9380812508157506 9 P21359,P13674,Q04656 3 +Negative regulation of muscle cell apoptotic process 0.4277637878308111 0.3807282072282938 0.7034049361077188 1.0 0.9382504022755576 7 Q8NDZ4 1 +Voluntary musculoskeletal movement 0.416765053128675 0.3784248497065264 0.7051150109521163 1.0 0.9396722049740588 3 P18887,Q96QK1 2 +Triglyceride biosynthetic process 0.4220284875330563 0.3778437184035009 0.7055466944142412 1.0 0.9399851693915142 5 Q8WTV0 1 +3 utr mediated mrna destabilization 0.424519940915808 0.377435314147259 0.7058501272682751 1.0 0.9399851693915142 6 Q14103,Q92945,Q13148,Q9HCE1,Q92900 5 +Dna dealkylation 0.4292048477682474 0.3773312946447197 0.7059274183033968 1.0 0.9399851693915142 8 P29372,Q8N3C0,Q93008,Q9C0B1,P27695,Q9NRW3,Q13263 7 +Negative regulation of cell growth 0.4603430422819768 0.3762589627696606 0.706724384448838 1.0 0.9401135512700548 30 Q15375,O75414,P50897,P36896,O94813 5 +Negative regulation of androgen receptor signaling pathway 0.4161747343565523 0.3761976816796025 0.706769938797327 1.0 0.9401135512700548 3 Q13547,P35232 2 +Protein hexamerization 0.4239196443514633 0.3751297859145981 0.7075639458967498 1.0 0.9405368420319722 6 Q96RR1 1 +Response to food 0.4261222340455703 0.3743770237842558 0.7081238345059337 1.0 0.9407930944150262 7 P31749 1 +Response to transforming growth factor beta 0.460987786337369 0.3730727055675205 0.7090943323615946 1.0 0.9415060378694636 33 P05556,P62942,Q9Y4E8,Q06481,O00560,P40763,Q92896,P08069 8 +Protein localization to early endosome 0.4200141147511223 0.3701714771957756 0.7112547273704526 1.0 0.9437050213619488 5 P15311,O75116 2 +Endothelin receptor signaling pathway 0.4143027117039113 0.3691648925165289 0.7120048222475956 1.0 0.9437050213619488 3 P29992 1 +Postsynaptic modulation of chemical synaptic transmission 0.4197317257093804 0.3691001513489583 0.712053076141197 1.0 0.9437050213619488 5 Q7L576,P40818,P06730 3 +Intracellular transport 0.2780921256161051 0.3690973610136561 0.7120551559032093 1.0 0.9437050213619488 585 Q99523,P07602,P05067,O75503,Q06481,P11717,Q07954,Q14108,Q8NBN3,Q15904,P10619,P13473,P11279,P61916,P27105,Q9NQ11,P31749,Q9BRG1,Q05D32,Q8TD16,O15118,Q13190,Q9H173,O43752,P21359,O60830,Q9Y6B6,Q92544,Q96D46,Q15070,P31751,Q9NV96,O43731,Q96BM9,O15260,P60604,O15400,Q9Y496,Q15041,Q9NUM4,O00560,P40763,Q9UN37,Q92572,Q9NVU7,Q13277,Q9UBX3,Q9H223,Q96EK5,Q16539,P20645,P55786,P84085,Q99595,O60784,P61421,P62258,Q9Y282,P40855,Q86Y82,Q14168,Q5JRA6,P61160,Q9H4M9,P46934,P46379,Q9UHY1,P31946,O95831,Q4J6C6,Q8TAG9,Q9C0C9,Q96N67,Q9UH99,Q969X5,O15027,Q12907,Q9Y3E7,O43464,P19784 80 +Positive regulation of oligodendrocyte differentiation 0.4168881015648195 0.3685170038664935 0.7124877686381903 1.0 0.9438940524693974 4 Q13547,Q92769,O14744 3 +Regulation of mrna 3 end processing 0.4486349322749587 0.3673229648170265 0.7133781261108125 1.0 0.9442144550908388 20 Q5VTR2 1 +Copii coated vesicle cargo loading 0.4265349449146899 0.3669837530071697 0.7136311370103141 1.0 0.944255833727062 8 Q5JRA6,O95486,O94979 3 +Regulation of nik nf kappab signaling 0.4402537407920545 0.3650410860961228 0.7150807370606072 1.0 0.9452133194445792 15 P15311,Q99829,P23396,P05067,P61586 5 +Regulation of canonical wnt signaling pathway 0.4591548447946827 0.3623625496549273 0.7170811215826829 1.0 0.9465121860306702 40 Q16539,O95071,Q9BZK7,P19022,Q9NWU2,Q99471,Q13641,O75787,O43293 9 +Epithelial cell cell adhesion 0.4147214446227308 0.3603885594210396 0.7185565809165684 1.0 0.9476911146205146 4 P15924 1 +Golgi vesicle transport 0.2832926766424495 0.3593382380979671 0.7193420720680184 1.0 0.9482278498739944 141 O15126,Q99523,Q8TD16,Q15334,Q8TAG9,Q13190,P57737,Q9P2R3,O43752,P24390,Q969X5,O15027,Q12907,Q9Y6B6,P42566,P84085,Q96MW5,P35606,Q7Z392,Q8TBA6,Q9Y282,P11279,O43731,P60520,O15260,Q5JRA6,O14828,Q9UHY1,Q9UBF2,Q99747,O95486,Q92572,Q4J6C6 33 +Hormone metabolic process 0.4579849692357236 0.3591368599451957 0.7194927082193385 1.0 0.9482278498739944 33 Q9UBM7,P07858,Q9HB40,P42892,Q8TAD4,P08069 6 +Histone h2a acetylation 0.4288564963272105 0.3587272802687261 0.7197991181904995 1.0 0.9482278498739944 10 Q96L91 1 +Protein localization to postsynapse 0.4219567920887332 0.3584182474122196 0.7200303380506432 1.0 0.9482278498739944 7 Q13277 1 +Cellular hormone metabolic process 0.4450737515351017 0.3583875183545678 0.7200533310787538 1.0 0.9482278498739944 19 P42892 1 +Cranial nerve development 0.4111570247933742 0.3574516212413598 0.7207537376307114 1.0 0.9482278498739944 3 Q9H061,P35222 2 +Negative regulation of fibroblast apoptotic process 0.4080849808203063 0.356649685831806 0.7213540763975539 1.0 0.9482278498739944 2 Q9BZZ5 1 +Regulation of phospholipid metabolic process 0.4283149817252242 0.3566275041287536 0.721370684337082 1.0 0.9482278498739944 10 P17655 1 +Leukocyte homeostasis 0.4344387259343625 0.3565626247204025 0.7214192617621324 1.0 0.9482278498739944 13 P31749 1 +Regulation of ossification 0.4303156541826715 0.3561482960906264 0.7217295102296919 1.0 0.9482278498739944 11 O75844,Q16539,Q8N5W9,Q6W2J9 4 +Positive regulation of cold induced thermogenesis 0.4368707021688683 0.3514554407839197 0.7252466959837651 1.0 0.9495888959883972 15 P08069,Q06481 2 +Response to bacterium 0.4385924177757173 0.3511180166344518 0.7254998120651108 1.0 0.9496956137543248 59 P04114,Q5KU26,Q8WTV0,P31749,Q9BTY2,P01889,Q9UQB8,P17655,Q9NZ08,P04439 10 +Cranial skeletal system development 0.4245215945917978 0.3505137684713115 0.725953159011522 1.0 0.9497498121312316 9 Q93074,Q9ULC3 2 +Organelle localization 0.2820359940864376 0.3484463250959558 0.7275050172851047 1.0 0.9508246662369066 184 P05556,Q9NVU7,Q86VS8,Q8TD16,Q15334,Q13277,O60313,Q96N67,Q9UH99,Q13190,Q9H4H8,O43752,Q96DB5,O15027,Q9Y6B6,P15311,Q9Y3E7,Q9HAS0,Q92783,O75153,Q96D46,P53350,P11279,P56545,O14777,O95772,Q6IAA8,Q86Y82,Q96GA3,Q8WUX9,O15400,P61160,Q14203,Q9Y496,Q9NQ11,P19022,P11234,P43034,Q9UBF2,Q96GC9,Q9NUM4,O00560,Q9UN37,Q92572,Q15154 45 +Negative regulation of gtpase activity 0.4213501079405172 0.3471582123520381 0.7284724625160406 1.0 0.9517069498252908 8 Q9Y624 1 +Alcohol catabolic process 0.4318252173826978 0.3462740199579324 0.7291367913544429 1.0 0.9519152015687576 13 Q9NX62 1 +Positive regulation of intracellular protein transport 0.4425365833421461 0.3460030569430271 0.7293404173662665 1.0 0.9519152015687576 56 Q15154,O00410,Q9Y6B6,P68036,Q16539,O95071,O43464,P19784,Q92544,P55786,P60953,P31751,Q9Y282,Q9NV96,P62258,P06493,P27105,O15078,Q92688,Q05D32 20 +Endosome organization 0.4542076684563743 0.3459730294071748 0.7293629839362463 1.0 0.9519152015687576 31 P51790,Q9Y3E7,Q14108,Q9BRG1,Q9UN37,O43752 6 +Regulation of cellular carbohydrate metabolic process 0.4535255531189274 0.3455057382414007 0.7297141970929786 1.0 0.9519918683517616 30 P31751,Q9BYT8,Q14108,P31749,Q92520 5 +Positive regulation of lipid localization 0.4349346627145417 0.3437500275017824 0.7310342846957343 1.0 0.9528737377915824 15 Q07954,P04114,Q8WTV0,Q9NV96 4 +Negative regulation of cell development 0.4516126011205703 0.3432337999367069 0.7314225787700415 1.0 0.953054387778006 28 P21359,Q15375,Q96G23,Q9UPY3,Q9UBS4,Q04917,Q06481,Q8N5W9,Q9P258,Q15154 10 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4528076060083219 0.3423044163472366 0.7321218123463455 1.0 0.953054387778006 30 Q12907,Q8TD16,P35606,P49755,Q9Y282,O43731,Q9P2W9,Q9H9E3,Q9UBF2,P84085,O14579,P24390,Q969X5 13 +Cation transmembrane transport 0.2804369893181266 0.3418503495376359 0.7324635162272641 1.0 0.95308688678655 130 P05556,P08195,P30825,Q7KZN9,Q04656,P05067,P07384,Q9H2J7,Q13423,Q70HW3,P11413,P61421,P51790,P62258,P62942,Q8TAD4,P27105,Q9NQ11,Q9NWR8,P35670,P06756,P46934,Q96GC9 23 +Regulation of catabolic process 0.2805729810467348 0.3417002559775728 0.7325764794497656 1.0 0.95308688678655 321 P05556,O95816,P07602,Q969Z0,O15118,P04062,P05067,Q13190,P98164,Q9H2J4,Q9H4H8,P07384,Q07954,Q16539,Q9C0B1,Q9H074,Q14108,Q8TBX8,Q8WTV0,O43464,P68402,O43293,Q14671,P53634,Q93050,Q5PRF9,P10619,P31751,P61421,Q9Y487,P67809,Q7Z739,Q9NQ11,P46934,Q9GZU8,P31749,Q9GZP4,P46379,O00560,P40763,Q6UWE0,O95831 42 +Fibroblast apoptotic process 0.4083259521700689 0.3367664019637132 0.7362930024503189 1.0 0.9567689708880354 4 Q13618,P04637,Q9BZZ5 3 +Positive regulation of establishment of protein localization 0.3119558850125057 0.3363857590217786 0.736579987088396 1.0 0.956818527004306 97 Q15154,O00410,Q9Y6B6,P15311,O95071,P68036,Q9Y5K6,Q16539,O43464,Q9H3S7,Q92544,P19784,P55786,P35580,P60953,P31751,Q9NV96,P62258,Q9Y282,P06493,P27105,Q9BUR4,Q9NQ11,O15078,Q92688,O95486,Q05D32 27 +B cell mediated immunity 0.4381408990331712 0.3362963765384205 0.7366473820807347 1.0 0.956818527004306 18 O96028,Q07021,P02786 3 +Tissue migration 0.4457026139128386 0.3345093500775132 0.7379952365314582 1.0 0.9578048225318564 52 P21359,Q15555,P05556,P04083,Q16539,Q99538,Q8WTV0,Q9H3S7,P31749,Q13685,P23634,Q5JRA6,P42785,O94813 14 +Amino acid homeostasis 0.4015933903806468 0.3330788532766786 0.7390747615184705 1.0 0.9584229148570474 2 O94925 1 +Negative regulation of carbohydrate metabolic process 0.4242387936793952 0.3327078544460851 0.7393548200325795 1.0 0.9584229148570474 11 Q92520 1 +Regulation of chromatin binding 0.4095040346801872 0.3310230213019182 0.7406270964394932 1.0 0.959446576040096 5 Q7Z5K2,P56545 2 +Positive regulation of blood vessel endothelial cell migration 0.4214180258923639 0.3302335355042641 0.7412235091766988 1.0 0.959698696249067 10 P04083,P31749 2 +Skeletal muscle organ development 0.4482719871438582 0.3286690859127155 0.7424058231786832 1.0 0.9607463226619826 28 P21359,P41440,P60660,Q16539,Q9BYT8,O75955,P61586,P14649 8 +Neuron projection extension 0.4508314029345734 0.3284868112958998 0.7425436146335354 1.0 0.9607463226619826 32 P05556,Q99829,Q9Y263,Q7L576,Q9UJU6,P43034,A0MZ66,Q96ST3,O94813 9 +Regulation of membrane protein ectodomain proteolysis 0.4059639799232451 0.3281866460873386 0.7427705440795327 1.0 0.9607463226619826 4 Q9UKS6,O43847,Q13464 3 +Neurotransmitter secretion 0.4442368552970682 0.3279683765369002 0.7429355732068901 1.0 0.960768887877802 24 P21359,Q13277,Q7L0J3,Q5SQN1,P50897,Q4J6C6 6 +Negative regulation of g protein coupled receptor signaling pathway 0.4135393560207467 0.3268860053647437 0.7437541062483688 1.0 0.9612545625723408 7 P31946 1 +Regulation of protein binding 0.4428898066493996 0.3254901002845226 0.7448101739132453 1.0 0.9619410490896846 53 P53350,P41440,O95816,Q9UBB9,Q9GZU8,P05067,P62942,O75955,P31749,Q96D46,P10586,Q07954 12 +Negative regulation of neuron projection development 0.4397294509669589 0.3247998912345701 0.7453325268681028 1.0 0.9622405125747636 21 Q96G23,Q15375,Q9UQ16,P43034,P61586,Q86X55 6 +Negative regulation of vasculature development 0.4351235339931801 0.3242017081410432 0.745785328953787 1.0 0.9623070714153936 18 P21359,Q9UHI8,Q9Y6I3,P23634 4 +Regulation of biological process involved in symbiotic interaction 0.419700878402361 0.3237655587923103 0.7461155329621283 1.0 0.9623070714153936 10 Q9BTY2 1 +Cellular response to hyperoxia 0.3983475951608212 0.3215173809513348 0.7478183428117071 1.0 0.9634469447267616 2 O95352 1 +Motor neuron apoptotic process 0.3983475951608147 0.3215173809513119 0.7478183428117244 1.0 0.9634469447267616 2 O75312 1 +Neurotransmitter biosynthetic process 0.398052522868104 0.3204739289589616 0.748609090722814 1.0 0.96389342970837 2 Q8NCG7 1 +Negative regulation of transport 0.3620654260742269 0.3198864944504306 0.7490543762521811 1.0 0.9638948387827038 85 Q08722,Q04656,P05067,Q06481,P21359,Q8N183,P04083,P31751,P62258,P62942,Q9P2B4,P60604,Q9ULC3,P06756,P46934,P31749,O00560,O75915,Q6UWE0 19 +Regulation of cell cycle phase transition 0.2779921369375367 0.3178530155334036 0.7505964338247526 1.0 0.9654043652335418 127 P05067,Q96ST3,Q06481,O60921,Q9H4H8,P23634,Q13564,Q9P258,Q13619,Q16539,Q96HY6,Q9UJX4,Q96DY7,P04083,P53350,O14777,P06493,Q9UHI8,Q9UJX5,Q9NXR7,P31749,O60934,Q9UN37 23 +Lipid catabolic process 0.3576320633082917 0.3149125195827387 0.7528280756368024 1.0 0.9670305391467214 86 Q8NCC3,Q99519,P04066,P04114,Q8NHP8,P06280,P06865,P17900,Q13510,P04062,P07686,P31749,Q8WTV0,P50897,P38571 15 +Negative regulation of nervous system development 0.4394198496528456 0.3128754606867581 0.7543752817903031 1.0 0.96724680243629 23 P21359,Q15375,Q96G23,Q9UPY3,Q9UBS4,Q04917,Q06481,Q15154 8 +Positive regulation of production of molecular mediator of immune response 0.4366670184996658 0.3123629394705142 0.7547647122698797 1.0 0.96724680243629 21 P02786,P04439 2 +Cellular response to indole 3 methanol 0.4015352819604436 0.312316652188866 0.7547998859402609 1.0 0.96724680243629 4 P14923,P35222,P38398 3 +Response to indole 3 methanol 0.4015352819604436 0.312316652188866 0.7547998859402609 1.0 0.96724680243629 4 P14923,P35222,P38398 3 +Autophagosome organization 0.445927267063343 0.312002899240577 0.75503831997024 1.0 0.96724680243629 30 Q9NQ11,Q6UWE0,P04062,Q8TBX8,Q86Y82,Q96GC9,Q9ULC3 7 +Pyrimidine ribonucleoside triphosphate metabolic process 0.4165351294087097 0.3119526138813911 0.7550765360954264 1.0 0.96724680243629 10 P15531,P17812,O75414,Q9NRF8 4 +Cellular modified amino acid catabolic process 0.4178198370242779 0.3085134946472446 0.7576916334602077 1.0 0.9692616494057678 11 Q9UJ14,Q9UHG3,Q8WUX2,Q8IYS1 4 +Protein localization to endosome 0.4176673116778053 0.3079459054182792 0.7581234944829496 1.0 0.9696235656353638 11 Q9UNF0,P15311,O75116,Q9NV96 4 +Regulation of immunoglobulin production 0.4272467402739481 0.3066253585758782 0.7591285494937186 1.0 0.970146615077367 16 P02786 1 +Necrotic cell death 0.4288322008409386 0.3059661358775273 0.7596304297207948 1.0 0.970571113746886 17 P00403,Q13572,Q13510,Q96HS1 4 +Regulation of defense response to virus 0.4251895536918548 0.3057651130496389 0.7597834928168514 1.0 0.970571113746886 15 Q8IZ81,O75844,Q07021 3 +Cytochrome complex assembly 0.4210003315007237 0.3046777331922153 0.7606116101284632 1.0 0.971088758959854 13 Q15070,Q69YU5 2 +Cellular response to leucine starvation 0.396103896103897 0.3033114078022975 0.7616525532673104 1.0 0.97128186535476 3 Q9P2J5,P42345 2 +Regulation of protein phosphorylation 0.2803411460009059 0.3032180629605863 0.7617236843569852 1.0 0.97128186535476 174 Q96AC1,Q15375,P04062,P05067,Q96N67,O60921,Q9H223,Q9H2J4,P23634,O00410,P02786,Q07954,P21359,Q96HY6,Q8ND04,Q8IXB1,O94813,P53350,P31751,Q8NDZ4,P41440,P10644,O75955,P11234,P31749,O00560,O60934,Q9BRG1 28 +Peptidyl threonine modification 0.4451186274725788 0.3031066481110908 0.7618085878773648 1.0 0.97128186535476 32 P53350,P05067,P31749,P19784,Q10472,Q10471,P36896 7 +Regulation of leukocyte proliferation 0.4369628433424132 0.302830466479016 0.7620190640405351 1.0 0.97128186535476 23 P04083,P10644,P02786,P04439 4 +Negative regulation of receptor internalization 0.4014236688339487 0.3019877881556114 0.7626613722592814 1.0 0.9716096934262078 5 O00560 1 +Maintenance of protein localization in endoplasmic reticulum 0.4010186819685915 0.3005580483242086 0.7637515256109157 1.0 0.972617846581976 5 O43731,O43292 2 +Protein retention in er lumen 0.4010186819685915 0.3005580483242086 0.7637515256109157 1.0 0.972617846581976 5 O43731,O43292 2 +Histone h4 k20 methylation 0.4028083486570525 0.2971814142047536 0.7663280105603076 1.0 0.973423482682459 6 O96028 1 +Negative regulation of hemopoiesis 0.4119544479357208 0.2951220867188759 0.7679006179865517 1.0 0.9748504335203688 10 P21359 1 +Positive regulation of establishment of protein localization to mitochondrion 0.4135705147200595 0.2928310675542572 0.7696512801617921 1.0 0.9755132093836906 11 P68036,Q9UBE0,O43464,P19784,P55786,Q9Y371 6 +Erbb signaling pathway 0.4331772486306516 0.2928209607018722 0.7696590058333945 1.0 0.9755132093836906 22 Q99538,P31749 2 +Multicellular organism growth 0.4419327740708246 0.291803866802128 0.7704365885732691 1.0 0.9756245359352868 31 Q9BZK7,Q9C0B1,Q99538,O43464,P05067,P40763,O75844 7 +Regulation of oxidative phosphorylation 0.4132147559514281 0.2915305315925133 0.7706455966055044 1.0 0.9756714962858486 11 P14406,Q04656 2 +Neuron projection regeneration 0.4127734173357671 0.2899198438379341 0.7718775601147438 1.0 0.9768512667859608 11 Q96G23,P00374,P08069 3 +Response to epidermal growth factor 0.4226637073442062 0.2890913087594526 0.7725115043905437 1.0 0.977083717424216 16 P31749 1 +Positive regulation of anion transport 0.4050897710733548 0.2874421761927971 0.7737737711480133 1.0 0.9779163646755608 8 P05556,Q15041 2 +Negative regulation of ubiquitin protein ligase activity 0.40743997908845 0.2872255186200981 0.7739396481193097 1.0 0.9779163646755608 9 P60866,O95816 2 +Establishment of protein localization to organelle 0.2779868398871792 0.2864038584062722 0.7745688198449576 1.0 0.978119959681788 191 Q99523,Q10713,Q9H1Z9,P56589,Q06481,O00410,Q8TEX9,P21359,O60830,O95071,Q16539,Q14108,O43464,P19784,Q92783,P20645,P55786,Q15070,Q99595,P13473,P11279,P40855,P06493,Q9ULC3,P46934,P31749,P46379,P40763,Q9BRG1,Q9UN37,Q6UWE0,Q96ES7,O95831 33 +Box c d snornp assembly 0.3938588721582584 0.2855034600258707 0.7752584539531793 1.0 0.978119959681788 4 Q9NWS0,P55769,Q9Y230 3 +Small nucleolar ribonucleoprotein complex assembly 0.3938588721582584 0.2855034600258707 0.7752584539531793 1.0 0.978119959681788 4 Q9NWS0,P55769,Q9Y230 3 +Regulation of neuron differentiation 0.4313321006454338 0.2854700806374222 0.7752840233422467 1.0 0.978119959681788 22 Q99829,P05067,Q13464,P61586,Q04917,Q96ST3,P26196,Q8WUJ1 8 +Cellular response to aldehyde 0.4018632773301563 0.2848399077944061 0.7757667961098691 1.0 0.978171837336081 7 P08069 1 +Regulation of nk t cell differentiation 0.3874299203304795 0.2837813406757846 0.7765779549050582 1.0 0.9783997295236458 2 O00203 1 +Nk t cell differentiation 0.3874299203304795 0.2837813406757846 0.7765779549050582 1.0 0.9783997295236458 2 O00203 1 +Antigen processing and presentation of lipid antigen via mhc class ib 0.3874299203304795 0.2837813406757846 0.7765779549050582 1.0 0.9783997295236458 2 O00203 1 +Regulation of transporter activity 0.4407475052004411 0.282631188108428 0.7774595700193272 1.0 0.9783997295236458 46 P05556,P62258,P46934,Q04656,P05067,P62942,Q04917,Q96GC9,P08183,P27105,Q9P2B4,P07384 12 +Pigmentation 0.4259558668868067 0.2819355473431473 0.7779929318572307 1.0 0.9786925577566322 19 P21359,Q04656,O75787,Q8TAA9 4 +Negative regulation of intracellular signal transduction 0.2921640340287775 0.2811826267815118 0.7785703291579058 1.0 0.9792296836974436 100 P05556,Q10713,O60313,P04062,P23634,P08069,P21359,P15311,Q16539,Q9Y5K6,O43464,P61586,P16989,Q07021,O94813,Q9H3F6,Q96KB5,Q96S59,Q7LG56,P13693,Q99829,O75489,P43034,P31749 24 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4137332781544347 0.2777257559510944 0.7812228876989029 1.0 0.9801042588012832 13 Q14671,Q9NUD5,Q07021 3 +Rig i signaling pathway 0.4137332781544347 0.2777257559510944 0.7812228876989029 1.0 0.9801042588012832 13 Q14671,Q9NUD5,Q07021 3 +Positive regulation of cell activation 0.4403337981373342 0.2761704020509035 0.7824171892558534 1.0 0.9806736104655932 44 Q08722,P04083,P11279,P31749,P53634,O96028,P02786,P04439 8 +Nadph regeneration 0.4043245498076282 0.2761538355365173 0.782429912866097 1.0 0.9806736104655932 9 Q13423 1 +Synaptic vesicle budding 0.387544273907913 0.2740330432596798 0.7840592283992056 1.0 0.981581841707468 3 Q13492,O00203 2 +Synaptic vesicle recycling via endosome 0.3875442739079128 0.274033043259679 0.7840592283992063 1.0 0.981581841707468 3 O00203,Q4V328 2 +Regulation of ion transport 0.3705494988243128 0.2723782699275545 0.7853311793664202 1.0 0.9824185199222512 81 P05556,P54709,Q04656,P05067,P08183,P23634,P07384,P11413,Q13555,P62258,Q7L0J3,P62942,Q8TAD4,P27105,P46934,Q15041,P31749,Q04917,Q96GC9,O75915,O75844 21 +Positive regulation of intracellular transport 0.3892473649012348 0.2715794737788933 0.7859453839984183 1.0 0.9829979730700678 75 Q15154,O00410,Q9Y6B6,P68036,Q16539,P15311,O95071,O43464,Q9H3S7,P19784,Q92544,P55786,P31751,P60953,Q9Y282,Q9NV96,P62258,P06493,P27105,Q9H4M9,O15078,P46934,Q92688,Q9UL25,Q05D32 25 +Myeloid dendritic cell cytokine production 0.3922031896042499 0.2700647599905384 0.7871104325389102 1.0 0.9836993100231632 5 Q9H2U1,Q92499,Q7Z434,Q9NY93 4 +Dendritic cell cytokine production 0.3922031896042499 0.2700647599905384 0.7871104325389102 1.0 0.9836993100231632 5 Q9H2U1,Q92499,Q7Z434,Q9NY93 4 +Positive regulation of dendritic cell cytokine production 0.3922031896042499 0.2700647599905384 0.7871104325389102 1.0 0.9836993100231632 5 Q9H2U1,Q92499,Q7Z434,Q9NY93 4 +Response to corticosteroid 0.4348952476638775 0.2683384204688211 0.7884388350057927 1.0 0.984981158297392 29 P04083,P04062,P16278,P19021,P08069,O94813 6 +Mammary gland epithelium development 0.401984834180273 0.2679397675138685 0.7887456824211541 1.0 0.984986455507714 9 P31749 1 +Regulation of reactive oxygen species biosynthetic process 0.3991451201459796 0.2666083126989341 0.7897707546351058 1.0 0.9858575844789188 8 P00403,P51790 2 +Regulation of lamellipodium assembly 0.4164008811424564 0.2656570858156549 0.7905033165867827 1.0 0.9858575844789188 16 Q04656,P61160,O94813 3 +Regulation of cell cycle g1 s phase transition 0.4383654466306541 0.2652441454633568 0.7908213892264055 1.0 0.9860653598666732 43 Q13619,P04083,Q96HY6,P31749,Q06481,Q9H4H8,P23634,Q9UHI8,Q96DY7 9 +Muscle cell apoptotic process 0.4137892985952682 0.2631334532877617 0.7924477202188949 1.0 0.987336776770336 15 Q8NDZ4,P17655 2 +Homotypic cell cell adhesion 0.4224266641712605 0.2623010485937766 0.7930893536603147 1.0 0.9873803198180624 20 Q14126,Q9Y624,P78310 3 +Embryonic morphogenesis 0.3819721715722908 0.2619114272549383 0.7933897293958867 1.0 0.9875654184258552 77 Q93074,Q93063,P67809,Q9NX62,P98164,P42892,P54802 7 +Positive regulation of chromatin organization 0.4001843211958634 0.2616785728296455 0.7935692614575314 1.0 0.9876000558379908 9 Q96ST3,Q8NEY8 2 +Regulation of gastrulation 0.3837072018890152 0.2612858811341338 0.7938720537230572 1.0 0.9877880484971526 3 Q8NBL1,Q7Z460 2 +Response to interleukin 7 0.3995177547123179 0.2593739737783117 0.7953467086715387 1.0 0.9884403985821264 9 P67809 1 +Axonal transport 0.425509232155453 0.2572420785739377 0.7969919026607686 1.0 0.9890447349818418 23 Q9Y496,O60313,Q96BM9,P43034,O60333,Q14168,Q9UL25,Q92572,Q14203 9 +Rrna base methylation 0.3937932225113975 0.2570111312923103 0.7971701801146154 1.0 0.9890447349818418 7 A6NJ78 1 +Regulation of axonogenesis 0.4267129069607228 0.256808142014407 0.797326884404356 1.0 0.9890447349818418 24 Q15375,P19022,Q7L576,Q9UJU6,A0MZ66,O94813 6 +Positive regulation of organelle assembly 0.4335481321323899 0.2561595992780911 0.7978276031436731 1.0 0.9891178245030112 31 Q15555,P48426,P11234,Q8TBX8,Q9P2W9,P61586,Q9P2S5,O00560,Q9H2M9,Q6UWE0,Q96C92,Q16181 12 +5 phosphoribose 1 diphosphate metabolic process 0.3844109831709509 0.2537737735813638 0.7996703359461457 1.0 0.9900825194008004 4 Q14558,P06737,P11908 3 +Pyrimidine ribonucleotide metabolic process 0.4046364821541021 0.2528598394875004 0.8003765245697356 1.0 0.9902035680252717 12 P15531,P17812,O75414,P11172,Q9NRF8 5 +Regulation of generation of precursor metabolites and energy 0.4357079195919319 0.2513961373964103 0.8015078537504952 1.0 0.99141480674819 39 P31751,P14406,Q04656,P05067,P31749,P40763 6 +Regulation of protein autophosphorylation 0.3993818316860578 0.2506024594915486 0.802121479992495 1.0 0.9916085899641364 10 Q15375 1 +Ruffle assembly 0.4013188204499653 0.2491924530915071 0.803211916894846 1.0 0.9922029561642216 11 P35241,P35080,Q7L576,Q9UJU6,P63000,Q9P258 6 +Phenol containing compound metabolic process 0.4092038893289154 0.2465716965580498 0.8052397111866614 1.0 0.9937650274550076 15 Q04656,P07858 2 +Neural tube formation 0.4181285498224636 0.2460908268980961 0.8056119238435384 1.0 0.9938475694943026 20 P98164 1 +Intestinal absorption 0.3976856032520336 0.2447924544030333 0.8066171367186787 1.0 0.9945222651588256 10 Q9Y624,Q9UDY2,Q8WTV0 3 +Positive regulation of meiotic cell cycle 0.3783943329397854 0.2440364359917983 0.8072026009813078 1.0 0.9946869402749 3 P30307,Q9H6S0 2 +Inflammasome complex assembly 0.3783943329397794 0.2440364359917788 0.8072026009813229 1.0 0.9946869402749 3 P19525,O00571 2 +Organelle inheritance 0.3972626604257729 0.243351276222904 0.807733285294949 1.0 0.9946963905766616 10 Q13190,P06493 2 +Establishment of centrosome localization 0.3838992249467157 0.2424833074397466 0.8084056897064835 1.0 0.9949669658845234 5 P15311 1 +Alcohol metabolic process 0.3288045160723342 0.2377610539681693 0.8120664269399058 1.0 0.9969233015728696 91 Q9UBM7,P04114,O15118,P04062,P05067,Q13510,Q15392,Q9NX62,Q8WTV0,P61916,P61457,Q9NWW5,Q13572,P48449 14 +Positive regulation of gene expression 0.2718452580895703 0.2372069793519904 0.812496222077139 1.0 0.9969233015728696 224 O15111,O95816,Q9P1Z2,P05067,P98179,Q9H2J4,O75787,P02786,Q13595,P15311,O95071,Q96HY6,Q16539,Q9H074,P61586,P36896,Q07021,P04083,Q9BY67,Q13144,P04114,P67809,P06493,O96028,Q15427,P04439,Q7Z739,Q9NUD5,P41440,Q9NQ11,P26583,O75955,P31749,P40763,P26368,Q567V2,O75844 37 +Cleavage furrow formation 0.3760330578512372 0.2365227090406824 0.8130270878371406 1.0 0.9969233015728696 3 P61586,Q9Y5X1 2 +Establishment of lymphocyte polarity 0.3790598219335469 0.2364551171870685 0.8130795311384675 1.0 0.9969233015728696 4 Q14254 1 +Acidic amino acid transport 0.3996639938279688 0.2356119602246561 0.8137337918015073 1.0 0.9969233015728696 12 P21359,O75915,P05556,Q15041 4 +Anoikis 0.3873304459289717 0.2354945268381351 0.813824926373854 1.0 0.9969233015728696 7 P31749 1 +Positive regulation of dna methylation dependent heterochromatin assembly 0.3845732388200399 0.2352772107457862 0.8139935819007407 1.0 0.9969233015728696 6 Q8NEY8 1 +Response to potassium ion 0.3816637781954246 0.2352553995032965 0.8140105097318322 1.0 0.9969233015728696 5 Q14168 1 +Cellular response to potassium ion 0.3816637781954246 0.2352553995032965 0.8140105097318322 1.0 0.9969233015728696 5 Q14168 1 +Positive regulation of nucleocytoplasmic transport 0.4267786960543587 0.2351901680649488 0.81406113674567 1.0 0.9969233015728696 29 Q16539,O95071,P62258,P46934,P06493,O00410,Q05D32 7 +Extrinsic apoptotic signaling pathway 0.4313672366640755 0.2318180551007958 0.8166793330691466 1.0 0.9969233015728696 42 P21359,P23229,Q9UNN5,Q99523,P06756,P26583,O43464,P31749,P36896 9 +Nucleobase containing small molecule biosynthetic process 0.386071198858817 0.2313844037757091 0.8170161804284484 1.0 0.9969233015728696 7 Q13126 1 +Glycosyl compound biosynthetic process 0.386071198858817 0.2313844037757091 0.8170161804284484 1.0 0.9969233015728696 7 Q13126 1 +Response to ethanol 0.4026441538602148 0.2307503514762102 0.8175087540857269 1.0 0.9969233015728696 14 P61586,P06493,Q9BRK5,P08069,P11413,P61160 6 +Regulation of reproductive process 0.4122718460467203 0.2306882221239491 0.8175570241456473 1.0 0.9969233015728696 19 P15291,P36896,Q07021 3 +Regulation of carbohydrate biosynthetic process 0.4103745218108348 0.2302394992626547 0.817905670224037 1.0 0.9969233015728696 18 Q92520,P31751,P31749 3 +Leukocyte differentiation 0.4089320847608367 0.2291882424138169 0.8187226105883694 1.0 0.9969854461149056 64 P21359,P04083,Q04656,P05067,P04062,O95251,P01889,P40763,Q15904,P02786 10 +Purine nucleotide catabolic process 0.3951753208725727 0.2282388274293228 0.8194605779958697 1.0 0.9973833764184332 11 O43598 1 +Mitotic spindle midzone assembly 0.3761440803070654 0.2272241795860916 0.8202494267951839 1.0 0.9979113751516812 4 O95239,O43663,Q9H0H5 3 +Histone h3 deacetylation 0.3786178381571258 0.2255450521844302 0.821555281527212 1.0 0.9985670057397652 5 Q9H4L7,Q92769,P23246,Q13547 4 +Histone h4 deacetylation 0.3786178381571236 0.2255450521844236 0.8215552815272171 1.0 0.9985670057397652 5 Q13547,Q9H4L7,Q92769,Q9UKL0 4 +Protein localization to condensed chromosome 0.3965775756693866 0.2251177852586775 0.8218876454271433 1.0 0.9986613726546756 12 Q96DY7,O14777,P06493 3 +Membrane fusion 0.4265662492940132 0.225038447790613 0.8219493642570943 1.0 0.9986613726546756 50 P04083,Q13277,O15400,P31751,Q9NQ11,Q13190,Q5SQN1,Q9UN37,O43752 9 +Torc2 signaling 0.3721959858323515 0.2245176576800265 0.8223545287548555 1.0 0.9986613726546756 3 Q9NWS0,Q96A49 2 +Immune response regulating cell surface receptor signaling pathway 0.4193066712553466 0.2232464955031826 0.8233436667503073 1.0 0.999248186156693 25 Q08722,Q13144,P46379,Q06481,P04439 5 +Aromatic amino acid family metabolic process 0.3828669480338692 0.2210495169529242 0.8250538775164789 1.0 1.0 7 P61457 1 +Cellular response to epinephrine stimulus 0.3704250295159357 0.219063585139314 0.8266005166559525 1.0 1.0 3 Q8IXJ6,P23634 2 +Response to epinephrine 0.3704250295159357 0.219063585139314 0.8266005166559525 1.0 1.0 3 Q8IXJ6,P23634 2 +Positive regulation of attachment of spindle microtubules to kinetochore 0.3762551683402328 0.2181242264070027 0.8273323218918034 1.0 1.0 5 Q00839,Q8IXJ6,Q9P258,P14635 4 +Regulation of release of cytochrome c from mitochondria 0.3966425642404662 0.2176983459802321 0.8276641524906863 1.0 1.0 13 Q9H3K2,P31749 2 +Cytosolic transport 0.398646017123427 0.2164187582838776 0.8286613457256764 1.0 1.0 68 Q99523,P15311,Q9Y3E7,P11279,Q9C0C9,Q13190,O75503,Q8NBN3,P57737,O15260,O43752,P61160,Q4J6C6,Q14203 14 +Anion transmembrane transport 0.426984046412757 0.2161378334622203 0.828880309781687 1.0 1.0 46 P41440,P05556,Q9UHG3,P08195,Q9UBX3,P30825,Q14728,P51790,Q15041,P98164,P51798,P51797,P08183 13 +Regulation of protein targeting 0.4160536619705298 0.2159828546469849 0.8290011121682888 1.0 1.0 24 P31751,P27105,O43464,P55786 4 +Protein demethylation 0.3784700005869487 0.2157993052689819 0.8291441898752576 1.0 1.0 6 Q8NB78,Q7LBC6 2 +Positive regulation of proteolysis 0.3092015674305441 0.2143252600671417 0.8302934209955273 1.0 1.0 95 P53350,O95816,Q96HY6,Q99538,P04062,P05067,O43464,P31749,P61586,P46379,O75915,O95831,Q9NWW5,P40763,Q9Y4X5,P53634,Q92542 17 +Negative regulation of neuron death 0.4272555601832909 0.2131246970571832 0.8312297016794643 1.0 1.0 41 Q9NQ11,Q01105,Q99538,P04062,P31749,P50897 6 +Viral budding 0.3927986665074907 0.2124951172052226 0.8317207867136722 1.0 1.0 12 Q9Y3E7,P46934,Q6UWE0,Q9UN37 4 +Positive regulation of ubiquitin protein transferase activity 0.3900206103895537 0.2111604795511137 0.8327620481557738 1.0 1.0 11 P53350,Q9BTE7,Q9Y297 3 +Cellular response to insulin stimulus 0.4176223403075335 0.2089540908038137 0.8344840776779068 1.0 1.0 56 P31751,Q8TBX8,P31749,Q06481,Q9UQB8,Q92572 6 +Regulation of ion transmembrane transport 0.4135377896002845 0.2081709750643617 0.8350954706767104 1.0 1.0 59 P05556,P62258,P54709,P46934,Q04656,P05067,P62942,Q15041,Q04917,Q96GC9,O75844,P08183,Q8TAD4,P27105,O75915,P11413,P07384 17 +Export across plasma membrane 0.3863387389294054 0.2071939363014226 0.8358584026991418 1.0 1.0 10 P62258,P54709,P35670,P05026,P08183 5 +Regulation of blood circulation 0.4203534878611985 0.2060218774863877 0.8367738221086651 1.0 1.0 30 P09493,P42892,P78310,Q14126,P10253 5 +Late endosome to vacuole transport 0.3875168618013064 0.203035209347371 0.839107512235004 1.0 1.0 11 Q9Y3E7,Q92783,Q9H3S7,Q9BRG1 4 +Regulation of supramolecular fiber organization 0.2897499325679701 0.2024263055981398 0.8395834651639196 1.0 1.0 99 Q08722,Q96AC1,Q9NUQ9,P58546,P09493,Q7L576,P05067,Q99471,P23396,P61586,Q9UJU6,O43293,Q9UQB8,O15511,Q13136,Q9Y624,O94813,Q14203 18 +Glycine metabolic process 0.3795217280161175 0.2020017351351477 0.8399153677026139 1.0 1.0 8 P00374 1 +Utp metabolic process 0.3765688846575589 0.2012635449652868 0.8404925061833284 1.0 1.0 7 O75414 1 +Definitive hemopoiesis 0.3642266824084991 0.2004142930910372 0.8411565819814792 1.0 1.0 3 Q13951,Q96JB5 2 +Asymmetric cell division 0.3727050661935041 0.1980062001759236 0.8430402127361458 1.0 1.0 6 P61160 1 +Nitric oxide synthase biosynthetic process 0.3633412042502931 0.1978067686059094 0.8431962502306136 1.0 1.0 3 Q02952,P42224 2 +Positive regulation of nitric oxide synthase biosynthetic process 0.3633412042502931 0.1978067686059094 0.8431962502306136 1.0 1.0 3 Q02952,P42224 2 +Cytoplasmic microtubule organization 0.3987074727334849 0.1961428239588158 0.8444983785286901 1.0 1.0 17 P15311,Q14203,P43034,P61586,P23258,Q15154 6 +Regulation of system process 0.3931397762625266 0.1960878055748942 0.8445414407217684 1.0 1.0 69 Q13555,P58546,P62258,Q9C0B1,P09493,P04062,P05067,Q9BT17,P42892,O43293,Q9UQB8,P78310,Q14126,P11413,P10253,P53634 16 +Wound healing 0.3993182389900624 0.1952898074305271 0.8451660759468202 1.0 1.0 66 P21359,P04083,P05556,Q16539,P09493,Q8WTV0,Q11206,P15291,P43121,Q13572,Q9BWH2,Q5JRA6,P42785,Q9Y624 14 +Regulation of protein containing complex assembly 0.279469032330804 0.1950097609617216 0.8453853061808423 1.0 1.0 101 Q9NUQ9,Q96AC1,Q9Y6B6,P58546,Q9UNN5,Q9UBB9,Q7L576,P04062,P23396,Q9UJU6,P61586,P11234,Q9UQB8,O15511,O94813,P02786,Q14203 17 +Mitotic nuclear membrane organization 0.3745054792398939 0.1949363337075077 0.8454427896020877 1.0 1.0 7 Q9UN37 1 +Midbrain development 0.4055645770164171 0.1945319212835472 0.8457594035365241 1.0 1.0 21 O15027,P62258,O75489,Q04917,P61586,Q16352,O14949,P11413,Q9UQR1 9 +In utero embryonic development 0.2936422897358192 0.1943158199502714 0.8459285991899654 1.0 1.0 98 P05556,Q9BZK7,P49321,Q04656,Q16706,Q8IWS0,Q96ST3,Q9ULT8,Q6W2J9,Q9UNS2,Q96EK5,Q13619,Q14574,P16989,P36896,Q9Y6I3,P04114,P67809,O43772,Q9BRT9,P31749,O60934,P17655 23 +Response to hydrogen peroxide 0.4069780721339783 0.193745928582129 0.8463748273562071 1.0 1.0 22 P04083,O95831,Q99720,P17655 4 +Positive regulation of developmental growth 0.4125262796277924 0.192998530361327 0.8469601190541483 1.0 1.0 26 P15311,Q16539,Q9Y263,Q7L576,Q9UJU6,P31749,P06493,A0MZ66,P16989 9 +Regulation of attachment of spindle microtubules to kinetochore 0.3765888264853657 0.1929264756789326 0.847016549943483 1.0 1.0 8 Q00839,Q9H0H5,P60953,Q96R06,Q8IXJ6,Q9P258,P14635 7 +Negative regulation of smoothened signaling pathway 0.3707533234859702 0.1921186063574622 0.8476493006217483 1.0 1.0 6 P22413,Q9Y297,P63244,Q2M1P5,P55072 5 +Negative regulation of intracellular protein transport 0.3864579908251303 0.1918888405458954 0.847829278961681 1.0 1.0 12 P21359,P60604 2 +Hematopoietic stem cell homeostasis 0.3643342190729342 0.1913728984864368 0.8482334515206384 1.0 1.0 4 Q9NX40,Q14157,Q9NVX2 3 +Protein polyubiquitination 0.4169275513448118 0.1893813889930939 0.849793909961162 1.0 1.0 53 Q9UIQ6,Q9C0C9,Q9H1A4,Q9ULT8,P52888,O95071,Q9UJX4,P55786,Q9Y4X5,Q8IU81,Q9Y297,Q9Y263,Q15386,Q5VTR2,P60604,Q13867,Q9UJX5,P46934,Q13616,Q6UWE0 20 +Regulation of translation at synapse modulating synaptic transmission 0.3635867132125522 0.1891887877962254 0.8499448550223072 1.0 1.0 4 Q7L576 1 +Ossification 0.4020435197542942 0.1891549619916962 0.8499713654885348 1.0 1.0 64 P21359,Q99523,Q16539,Q93063,P31749,Q9NX62,Q9UBG0,Q8N5W9 8 +Regulation of heart rate 0.3826937301513843 0.1877035149295804 0.8511090747333365 1.0 1.0 11 Q14126,P09493 2 +Hepatocyte growth factor receptor signaling pathway 0.3662138216184158 0.1876994450239021 0.8511122653447014 1.0 1.0 5 P16949,P63000,Q8IXJ6,Q9NWH9 4 +Histone h3 acetylation 0.3919756333617411 0.1875825447478321 0.8512039106093696 1.0 1.0 15 Q96ST3,Q9NRF9,Q96ES7,O95251 4 +De novo protein folding 0.4033202173975595 0.186682048830097 0.851909931620441 1.0 1.0 21 O14657,P48723,P62942,Q99543 4 +Response to acid chemical 0.4089011392480683 0.184613066523582 0.8535325365099009 1.0 1.0 25 Q04656,P61586,Q6IAA8,Q9UQB8,P23634,P17655,O00410,P08069,O95831 9 +Tube formation 0.4056685204056582 0.1835373418202844 0.8543764218365026 1.0 1.0 23 Q13308,P63104,O60313,Q93074,O15078,P11233,P98164,Q9ULT8 8 +Positive regulation of lipid transport 0.3787075339238271 0.1831972881687288 0.8546432220890043 1.0 1.0 10 Q07954 1 +Epithelial tube formation 0.4039767181369346 0.1831729536706061 0.8546623151557675 1.0 1.0 22 P98164 1 +Negative regulation of posttranscriptional gene silencing 0.3644418192557674 0.1825218054857763 0.855173243467874 1.0 1.0 5 O75844,P04637,Q08209,Q15717 4 +Head morphogenesis 0.367348683482758 0.1820162003986582 0.8555700121898624 1.0 1.0 6 Q15042,O75787 2 +Digestive system process 0.3847999737619251 0.1790924606121403 0.8578651018613339 1.0 1.0 13 Q9Y624,Q9UDY2,Q8WTV0 3 +Response to mechanical stimulus 0.4038795488526826 0.1772461524687646 0.8593150450943003 1.0 1.0 23 P58546,Q16539,P51797,P08069,Q9Y624 5 +Positive regulation of protein deubiquitination 0.3550767414403805 0.1741685132428837 0.8617330300961179 1.0 1.0 3 Q15020,P55072 2 +Substantia nigra development 0.3939340406356447 0.173576709860735 0.8621981369840297 1.0 1.0 18 O15027,P62258,O75489,Q04917,P61586,Q16352,P11413,Q9UQR1 8 +Somatic diversification of immunoglobulins involved in immune response 0.3895519180100876 0.1727265318445255 0.8628663878391309 1.0 1.0 16 O96028,P02786 2 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3895519180100876 0.1727265318445249 0.8628663878391314 1.0 1.0 16 O96028,P02786 2 +Positive regulation of dna binding transcription factor activity 0.4170108640083808 0.170527624578011 0.8645952112447444 1.0 1.0 39 P58546,O75955,P05067,P31749,P40763,P02786 6 +Deoxyribonucleoside monophosphate biosynthetic process 0.3569263803696837 0.170188253743585 0.8648620891166969 1.0 1.0 4 P34896 1 +Negative regulation of organelle organization 0.2610064851185228 0.1694331386184559 0.8654559594546454 1.0 1.0 112 P58546,Q9H3K2,O14777,P31749,O60934,Q99536,P02786,Q9Y624,O94813,Q96DY7 10 +Negative regulation of protein polyubiquitination 0.3561765621181738 0.1681015494745771 0.8665033903937311 1.0 1.0 4 O95071 1 +Negative regulation of protein k63 linked ubiquitination 0.3561765621181738 0.1681015494745771 0.8665033903937311 1.0 1.0 4 O95071 1 +Protein autophosphorylation 0.4151483557471916 0.1680544997390457 0.8665404041184086 1.0 1.0 36 Q15375,Q9NQ11,P31749,O43293,P08069,P36896 6 +Regulation of production of molecular mediator of immune response 0.4037089740936723 0.1661012473892982 0.8680772725187871 1.0 1.0 25 P02786,P04439 2 +Intracellular sterol transport 0.3773232155933221 0.1635091813812811 0.8701175447382894 1.0 1.0 12 P61916,O15118 2 +Positive regulation of cell cycle 0.2994476455790968 0.1624118052284598 0.8709815750326393 1.0 1.0 96 P05067,Q96ST3,Q9H4H8,P08069,Q9P258,Q13619,Q96HY6,Q99538,Q9UJX4,Q13620,P61586,Q96DY7,P04083,O14777,P06493,O95785,Q9UHI8,Q9UJX5,P31749 19 +Regulation of adherens junction organization 0.3505731143631703 0.1618280560892867 0.8714412586809834 1.0 1.0 3 Q9H3S7 1 +Negative regulation of protein modification process 0.2661149406910753 0.1607879846990051 0.8722603889247558 1.0 1.0 126 O95816,P04062,Q96ST3,P60866,P23634,O00410,Q07954,P21359,O95071,P11413,Q8IXB1,O94813,P53350,Q96KB5,P62258,Q9BX68,Q32P28,P62942,P29375,Q01105,P10644,P31749,P31946,P26368,Q9BRG1 25 +Development of primary female sexual characteristics 0.3783788393786807 0.1592523108184542 0.873470091619504 1.0 1.0 13 O94813 1 +Positive regulation of torc1 signaling 0.3558771411695277 0.1583299818936211 0.8741967839691971 1.0 1.0 5 Q9NWS0,Q9Y4R8,Q9P2J5,Q96EE3 4 +Digestion 0.380184446361112 0.1574619373947224 0.8748808031976938 1.0 1.0 14 Q9Y624,Q9UDY2,Q8WTV0 3 +Positive regulation of mapk cascade 0.414419916137488 0.1573208269396184 0.8749920071113773 1.0 1.0 44 Q96AC1,P60953,P18615,P19022,P23396,P05067,Q13641,Q13464,O75915,Q6IAA8,O00560,P08069 12 +Negative regulation of nucleocytoplasmic transport 0.3671362729137963 0.1567347702594604 0.8754538830284988 1.0 1.0 9 P21359,Q9ULC3 2 +Regulation of atp metabolic process 0.405036555851818 0.1566097202185493 0.8755524414550209 1.0 1.0 28 P14406,P05067,P40763 3 +Histone h4 k16 acetylation 0.3637720273148943 0.1551475678942327 0.87670498240824 1.0 1.0 8 O95251 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.3817320009055464 0.1550902329046389 0.8767501820330701 1.0 1.0 15 Q92896,O00560 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.3513433717153928 0.1549092032816386 0.8768928980657584 1.0 1.0 4 Q96HY6,P63244,P18031 3 +Mitochondrial electron transport cytochrome c to oxygen 0.360766272863532 0.1548275648839516 0.8769572596057795 1.0 1.0 7 Q7KZN9 1 +Regulation of embryonic development 0.3920168630383134 0.1546502591695879 0.8770970455137137 1.0 1.0 20 P43034,P46379,Q9H9B1,P06493,Q16181,Q9UK39 6 +Mitochondrial dna metabolic process 0.3604569048654987 0.1539657995618371 0.8776367019874978 1.0 1.0 7 Q13472 1 +Intra golgi vesicle mediated transport 0.3898719795603086 0.153939301706542 0.8776575951457883 1.0 1.0 19 O14579,Q9Y2V7,P60520,Q9H9E3,Q9UBF2,Q99747,Q96MW5,P35606,Q8TBA6 9 +Postsynaptic membrane organization 0.3602316311673013 0.1533394518055251 0.8781305904981735 1.0 1.0 7 P19022,Q9NQX3 2 +Multivesicular body organization 0.3809802048428871 0.1527851880551271 0.8785676788073475 1.0 1.0 15 Q9UN37,Q92783,Q9Y3E7,Q9BRG1 4 +Synapse maturation 0.3504576321228323 0.1525403656310316 0.8787607557606749 1.0 1.0 4 Q9UJX6,P63104,P07196 3 +Cellular lipid catabolic process 0.3836562102015708 0.1516730814957008 0.879444789357489 1.0 1.0 70 Q8NCC3,Q99519,P04066,P04114,Q8NHP8,P06280,P06865,P17900,P04062,Q8WTV0,P07686,Q13510,P31749,P50897 14 +Signal transduction in absence of ligand 0.3849658456197002 0.1514013744430569 0.8796591053126543 1.0 1.0 17 P21359,O43464,P06756,P31749 4 +Negative regulation of cellular protein catabolic process 0.4069160209678129 0.1512988742626753 0.8797399572683773 1.0 1.0 31 Q9NQ11,Q96HY6,Q9GZU8,P46379,P19784,Q9H2J4,O00560 7 +Regulation of receptor internalization 0.3700167405563455 0.1494854950990558 0.8811705540038612 1.0 1.0 11 P41440,O00560,O75955 3 +Interleukin 2 production 0.3616160727551426 0.1491009699400794 0.8814739605451001 1.0 1.0 8 P04083,P15311 2 +Pyrimidine ribonucleoside diphosphate metabolic process 0.3489813994685597 0.1486261626457181 0.8818486274895208 1.0 1.0 4 P11172,P30085,Q05682 3 +Immune response regulating signaling pathway 0.4066184706364321 0.1476302240665582 0.8826346010975328 1.0 1.0 55 Q08722,Q9NUD5,P04439,Q13144,Q5KU26,O75955,P46379,Q9Y4E8,Q06481,Q14671,Q07021,Q9NPR9 12 +Regulation of stem cell differentiation 0.3834294257531734 0.1466260415175429 0.8834271976792272 1.0 1.0 17 Q9Y6C9,P40763,Q96PZ0 3 +Smooth muscle cell proliferation 0.3947274286074569 0.1460382638127498 0.8838911820681801 1.0 1.0 23 P09493,P31749,Q9UHI8 3 +Protein folding 0.2602352530430988 0.1451353917861107 0.8846039755096589 1.0 1.0 104 O95816,Q32P28,Q9UNP9,Q9UBS4,P62942,P40855,O14657,Q15185,Q99614,Q9H2J4,Q6ZRP7,Q9H173,O60884,Q9NUG6,P48723,Q99543,Q8IXB1 17 +Cellular response to oxygen levels 0.4103564700966791 0.1450825016880326 0.8846457337365632 1.0 1.0 38 P61421,Q9Y487,Q04656,P31749,P55786,Q15904 6 +Keratinocyte differentiation 0.3870441988266524 0.1449312967906733 0.8847651160425811 1.0 1.0 19 P04083,Q13510,Q16739 3 +Protein localization to microtubule organizing center 0.3710052805036032 0.1448150037754515 0.8848569358031686 1.0 1.0 12 Q86VS8,Q8IVD9,Q13561,Q9P2S5,Q9UIS9,Q15154 6 +Cell cycle g1 s phase transition 0.3941517033123898 0.1447714403524294 0.8848913319306715 1.0 1.0 64 Q13619,P31350,P05556,P04083,Q96HY6,P49321,P06730,Q13620,P31749,P15927,Q06481,Q9H4H8,P23634,Q9UHI8,Q13616,Q8N6R0,P36896,Q96DY7 18 +Response to oxidative stress 0.2795264590281633 0.1442670069146952 0.8852896303923516 1.0 1.0 100 P00374,P04083,Q9UJ14,O15111,Q9NQ11,P09493,P04062,P05067,Q04656,P31749,Q15392,O43464,O95831,P17655,P11413,P28074,Q99720,O95168 18 +Positive regulation of type i interferon production 0.3865051687893128 0.1432322940618325 0.8861067257893365 1.0 1.0 19 Q9NUD5,O15111,O75955,P41440 4 +Positive regulation of tor signaling 0.3560874704491859 0.1419935027396846 0.8870851377493452 1.0 1.0 7 Q6IAA8,Q9Y4R8,Q9P2J5,Q9Y2Q5,Q9NWS0,Q96EE3 6 +Torc1 signaling 0.3560874704491825 0.1419935027396753 0.8870851377493525 1.0 1.0 7 Q9Y4R8,Q9P2J5,Q6PKG0,Q9NWS0,Q96EE3,P42345 6 +Muscle cell development 0.4039807805680895 0.1405951497406087 0.8881897801232348 1.0 1.0 31 P05556,P09493,P10644,P06493,Q16527,O75844,P78310,P11413 8 +Vesicle mediated transport in synapse 0.4091505827167509 0.1403259838818024 0.8884024352699305 1.0 1.0 38 Q13277,P51790,Q9UQ16,P19022,Q7L576,Q7L0J3,P56545,Q5SQN1,Q4J6C6 9 +De novo pyrimidine nucleobase biosynthetic process 0.349084465445963 0.140146181939951 0.8885444927107473 1.0 1.0 5 P11172,P30085,P42345,Q05682 4 +Ump biosynthetic process 0.349084465445957 0.1401461819399352 0.8885444927107597 1.0 1.0 5 P11172,P30085,Q9BZX2,Q05682 4 +Pyrimidine ribonucleoside monophosphate metabolic process 0.349084465445957 0.1401461819399352 0.8885444927107597 1.0 1.0 5 P11172,P30085,Q9BZX2,Q05682 4 +Regulation of cytoplasmic translation 0.3789650134812001 0.1397497566576863 0.8888577119856258 1.0 1.0 16 Q9H074,P67809 2 +Negative regulation of cell cell adhesion 0.3850651139155701 0.1387219241915792 0.889669892607845 1.0 1.0 19 P04083,P10644,P31749 3 +Maintenance of dna methylation 0.3445527015057671 0.1371391766999766 0.8909207864658868 1.0 1.0 4 Q9NRZ9,Q93009,P26358 3 +Dsrna processing 0.3845405204234573 0.1370892461372946 0.890960252554523 1.0 1.0 19 Q14671,P40763,Q15631,Q9UPY3 4 +Regulation of early endosome to late endosome transport 0.3682698989795238 0.1369643030143001 0.8910590112145043 1.0 1.0 12 Q9Y3E7,P15311,Q9H3S7 3 +Protein localization to cell cortex 0.3471653569801325 0.1351725022848124 0.8924754875293743 1.0 1.0 5 P53350 1 +Regulation of proton transport 0.3562893393562042 0.134551891609736 0.8929661805298368 1.0 1.0 8 Q04656 1 +Bicarbonate transport 0.3400236127508891 0.134455269643597 0.8930425794948005 1.0 1.0 3 P04920,Q9Y6M7 2 +Negative regulation of cysteine type endopeptidase activity 0.3893860388661204 0.1342655799363105 0.893192569986232 1.0 1.0 22 P31749,Q15392 2 +Cellular response to peptide hormone stimulus 0.3886203116817131 0.1335735022114061 0.893739838559199 1.0 1.0 66 P31751,Q8TBX8,P31749,Q06481,P40763,Q9UQB8,Q92572 7 +Regulation of small molecule metabolic process 0.4036846550908303 0.1333606448129753 0.8939081682272154 1.0 1.0 55 Q9UBM7,P04083,P04114,P31751,Q9BYT8,P05067,P31749,Q06481,Q92520 9 +Response to metal ion 0.3847404944960844 0.133243496345748 0.8940008123954588 1.0 1.0 68 O15111,O15118,Q04656,P05067,P02786,Q99538,Q9NQX3,P19021,P11413,Q13144,P06493,Q8TAD4,Q14168,Q9NQ11,O60888,P35670,P46934,P31749,Q92542 19 +Actin filament bundle organization 0.408455913443861 0.1321627915712026 0.89485553092853 1.0 1.0 45 Q08722,Q96AC1,P05556,P15311,P60953,P35080,P09493,Q13464,P61586,A0MZ66,P12814,Q9UQB8,Q8N5W9,Q13136,Q9Y624,O75116,Q13177 17 +Purine nucleotide transport 0.3661929968722044 0.1311029229509982 0.8956938889420567 1.0 1.0 12 Q08722,P41440 2 +Autophagosome maturation 0.3802894633854962 0.1304503782669753 0.8962101109814657 1.0 1.0 18 P13473 1 +Regulation of lipid localization 0.3991857243855012 0.1274541112530735 0.898580990814785 1.0 1.0 30 Q9Y6B6,P04114,P31751,Q9NV96,Q9H4M9,Q8WTV0,P31749,O15260,Q07954 9 +Histone h3 k36 methylation 0.3434752338484523 0.125813930560051 0.899879214408821 1.0 1.0 5 O96028 1 +Purine ribonucleoside metabolic process 0.3529359796412523 0.1256810289720594 0.899984419463425 1.0 1.0 8 Q13126 1 +B cell activation involved in immune response 0.3763562465824611 0.1252515816288902 0.9003243824934619 1.0 1.0 17 O96028,P02786 2 +Reactive oxygen species biosynthetic process 0.3583487056251873 0.124584530822141 0.9008524755881024 1.0 1.0 10 P00403,P51790 2 +Cellular component assembly involved in morphogenesis 0.3862669955781618 0.1243666615456008 0.9010249686116438 1.0 1.0 22 Q8N3R9,P05556,Q9UPY3,P09493,P10644,P43034,Q16527 7 +Pyrimidine nucleoside monophosphate metabolic process 0.3492907801418586 0.1241183061020767 0.9012216040617786 1.0 1.0 7 P30085,Q9BZX2,P33316,P11172,Q05682,P34896 6 +Pyrimidine nucleoside monophosphate biosynthetic process 0.3492907801418586 0.1241183061020767 0.9012216040617786 1.0 1.0 7 P30085,Q9BZX2,P33316,P11172,Q05682,P34896 6 +Pyrimidine nucleobase biosynthetic process 0.3492907801418561 0.1241183061020703 0.9012216040617838 1.0 1.0 7 P17812,P30085,Q05682,P11172,P42345,Q9NRF8 6 +N acetylneuraminate metabolic process 0.3392382639504042 0.1238658894187284 0.901421461209893 1.0 1.0 4 Q8NFW8,Q9UJ70,P46926 3 +Modulation by host of symbiont process 0.3876981855665659 0.1232149590684287 0.9019368802085256 1.0 1.0 23 P11717 1 +Negative regulation of cilium assembly 0.3353010625737935 0.122911120558179 0.9021774794694322 1.0 1.0 3 P50570,P50395 2 +Spliceosomal tri snrnp complex assembly 0.359804368728537 0.1209761107178366 0.903709957085986 1.0 1.0 11 O43395,Q9UHI6,Q9Y312 3 +Reproductive system development 0.3844532450897091 0.120552947410257 0.9040451394583228 1.0 1.0 67 P07858,P07602,Q15392,P98164,Q9UHI8,O94813 6 +Phosphorylation 0.2710411678571665 0.1195125357784324 0.904869309102054 1.0 1.0 328 Q15375,Q96AC1,O15111,O75414,Q8TD19,O43252,P04062,P05067,Q96N67,O60921,Q9H223,Q9H2J4,P23634,O00410,P08069,P02786,Q07954,P21359,Q5KU26,Q16539,Q96HY6,Q8TBX8,Q9HBU6,P19784,P61586,Q9Y4E8,O43293,Q8ND04,P36896,Q8IXB1,O94813,P23229,P53350,Q13555,P31751,Q9HA64,P06493,Q8NDZ4,P41440,Q9NQ11,P10644,O75955,P11234,P31749,Q15185,Q9UHY1,O00560,Q13572,P40763,O60934,Q9BRG1,P46020,O75844 53 +Vascular associated smooth muscle cell proliferation 0.3617669237376901 0.1189011296135215 0.9053536868097604 1.0 1.0 12 Q9UHI8 1 +Regulation of cation transmembrane transport 0.4046356558497643 0.1182825665563461 0.9058437702960802 1.0 1.0 48 P05556,P62258,P54709,P46934,Q04656,P05067,P62942,Q04917,Q96GC9,Q8TAD4,P27105,P11413,P07384 13 +Action potential 0.3839708262898392 0.1172084359218686 0.9066948821002369 1.0 1.0 22 P62258,P04062,Q04917,P15924,P05026,P78310,P29992,Q14126 8 +Macromolecule deacylation 0.4039555928287144 0.1167409182038114 0.9070653639105032 1.0 1.0 40 Q9UMR5,Q96ES7,P50897 3 +Striated muscle adaptation 0.3388877121857823 0.1145584552156581 0.9087951107749102 1.0 1.0 5 Q13555 1 +Response to angiotensin 0.3422869485875571 0.1144883436125577 0.9088506860908692 1.0 1.0 6 P08069,Q13464,O75116 3 +Negative regulation of vascular associated smooth muscle cell proliferation 0.3422682331637154 0.1144425508724109 0.908886984831396 1.0 1.0 6 P09493 1 +Positive regulation of canonical wnt signaling pathway 0.3790488588479078 0.1141293038517576 0.9091352928756662 1.0 1.0 20 O95071,Q9BZK7,Q13308,P40818,Q9NWU2,P14923,O43293,O75787 8 +Demethylation 0.3697934652034226 0.1129899753497415 0.9100385028287854 1.0 1.0 16 Q9Y4U1,Q8NB78,Q7LBC6,Q9C0B1 4 +Negative regulation of histone h3 k9 methylation 0.3336285798641931 0.1104668930954916 0.912039104627794 1.0 1.0 4 Q9NWS0,P26358,P38398 3 +Mitochondrial genome maintenance 0.3526688088308289 0.1096965334286334 0.9126500497487512 1.0 1.0 10 Q9BQP7,Q13472 2 +Regulation of extrinsic apoptotic signaling pathway 0.394768738508645 0.1081956342267661 0.913840508009936 1.0 1.0 31 P21359,P23229,Q9UNN5,P06756,P26583,O43464,P31749 7 +Hemostasis 0.3909264132440745 0.1081453444090744 0.9138803994132508 1.0 1.0 28 Q13572,Q9BWH2,Q9Y624,Q11206 4 +Regulation of mrna export from nucleus 0.3360897814530512 0.1079014796256835 0.914073843404834 1.0 1.0 5 Q9ULX6,Q08J23,Q7KZ85,Q96ST2 4 +Plasma membrane tubulation 0.3426409225000948 0.1075244294180016 0.914372945794962 1.0 1.0 7 Q5T0N5,Q9UNF0,Q9Y371 3 +Regulation of protein export from nucleus 0.3626291477798772 0.106942058717636 0.9148349464626296 1.0 1.0 14 Q92688,P62258,Q05D32 3 +Regulation of response to cytokine stimulus 0.3841607289837855 0.1066188922726759 0.9150913301517504 1.0 1.0 24 O94813 1 +Regulation of necrotic cell death 0.3543322248692839 0.1065641143640029 0.9151347890124348 1.0 1.0 11 P00403,Q13510 2 +Nucleotide binding oligomerization domain containing 2 signaling pathway 0.3276269185360166 0.105102586464324 0.91629440697176 1.0 1.0 3 Q96RT1,P0DMV9 2 +Response to heat 0.3992219156115279 0.104703669072076 0.9166109504696308 1.0 1.0 37 P21359,P62258,O43464,P31749,O60884,Q99543 6 +Adenylate cyclase activating g protein coupled receptor signaling pathway 0.337370753323489 0.1027028469568457 0.9181988140510032 1.0 1.0 6 P04899,Q14344,P23634,Q9Y4G8,P49840 5 +Vascular associated smooth muscle contraction 0.3301158223698367 0.1023990115667497 0.9184399682049188 1.0 1.0 4 P61586 1 +Negative regulation of regulated secretory pathway 0.3300856214939536 0.1023307293381281 0.9184941648442008 1.0 1.0 4 Q06787,P09601,P04899 3 +Secondary alcohol metabolic process 0.4001023755759568 0.0978352546250071 0.9220631125161978 1.0 1.0 44 Q9UBM7,O15118,P04062,P05067,Q8WTV0,Q15392,P61916,Q9NWW5,P48449 9 +Regulation of establishment of protein localization 0.265791451457097 0.0977300111572685 0.9221466841648522 1.0 1.0 144 Q15334,Q15154,O00410,P46060,P21359,Q9Y6B6,P15311,O95071,P68036,Q9Y5K6,Q16539,O43464,Q9H3S7,Q92544,P19784,P19021,P55786,Q8N183,P35580,P31751,P62258,Q9NV96,Q9Y282,Q32P28,P06493,P27105,P60604,O96028,Q9ULC3,Q9BUR4,Q9NQ11,Q92688,O95486,P50416,Q05D32 35 +Glucan biosynthetic process 0.3560013152602554 0.0964765096333158 0.9231421294843004 1.0 1.0 13 P31751,P31749,Q15185 3 +Protein import 0.3200534660158505 0.0963227567009062 0.9232642378850344 1.0 1.0 89 P21359,O60830,Q16539,P13473,P56589,P40855,P31749,P06493,Q06481,O95831,P40763,O00410,Q9ULC3,Q99595,Q8TEX9 15 +Tor signaling 0.3764235031518587 0.0944651450091086 0.9247396688517352 1.0 1.0 22 O75844,P04062,Q9H4H8,P31749 4 +Regulation of cell cell adhesion mediated by integrin 0.3186780761286503 0.0939788932337396 0.9251259232785742 1.0 1.0 2 Q9H4A3 1 +Regionalization 0.3830209959977612 0.0926242203102476 0.9262021014357592 1.0 1.0 26 P98164,Q93074,Q9Y2W6 3 +Organic hydroxy compound catabolic process 0.3598123837993293 0.0925541483679631 0.9262577716210084 1.0 1.0 15 Q9NX62 1 +Positive regulation of organic acid transport 0.3361110700803099 0.0921034501649395 0.926615847271388 1.0 1.0 7 Q15041 1 +Rac protein signal transduction 0.3540852716884581 0.091577294925365 0.9270338916560832 1.0 1.0 13 P21359,Q7L576,Q9UJU6 3 +Regulation of calcineurin mediated signaling 0.3287064382752611 0.0910959549419746 0.9274163467691235 1.0 1.0 5 P42345,P26599,Q9UHD1,P23634 4 +Regulation of map kinase activity 0.3639636157470423 0.0902820658230919 0.9280630713457184 1.0 1.0 17 P04062 1 +Inorganic ion transmembrane transport 0.2587349764736204 0.0896195386201225 0.9285895573106436 1.0 1.0 121 P05556,P08195,Q9UBX3,Q04656,Q9H2J7,Q13423,P51797,P61421,P51790,P62258,P62942,Q8TAD4,P27105,Q9UHG3,Q9NWR8,P35670,P06756,P46934,P51798,Q96GC9 20 +Cellular response to corticosteroid stimulus 0.3525181633913139 0.0876273295877132 0.930172879856723 1.0 1.0 13 P04083,P68036,Q13185,P06730,P20020,P08069,O95831 7 +Positive regulation of neuron apoptotic process 0.3522764020291718 0.0870225401793861 0.9306535955985744 1.0 1.0 13 P21359,Q15375,O95831 3 +Negative regulation of smooth muscle cell proliferation 0.3368836232879035 0.0863656008584437 0.9311757912636832 1.0 1.0 8 P09493,P61586 2 +Secretion by tissue 0.3187721369539602 0.08602987478904 0.9314426686099322 1.0 1.0 3 P53621,Q9H4A3 2 +Purine deoxyribonucleoside triphosphate metabolic process 0.318772136953958 0.0860298747890355 0.9314426686099356 1.0 1.0 3 Q9Y3Z3,P55263 2 +Cellular response to virus 0.377328470820434 0.0859203226432967 0.9315297561169372 1.0 1.0 24 Q9NUD5,O15111,Q16539,Q14671,Q07021 5 +Cell death in response to oxidative stress 0.3734686086597051 0.0858939552948629 0.9315507167292412 1.0 1.0 22 Q99720,P31749 2 +Er associated misfolded protein catabolic process 0.3357793432055819 0.0838549116365762 0.9331717885425326 1.0 1.0 8 Q9BUN8,P46379 2 +Calcineurin mediated signaling 0.3288035450517018 0.0833399174738299 0.9335812611214284 1.0 1.0 6 P26599,Q9UHD1,Q08209,P23634,P42345 5 +Inositol phosphate mediated signaling 0.3288035450517018 0.0833399174738299 0.9335812611214284 1.0 1.0 6 P26599,Q9UHD1,Q08209,P23634,P42345 5 +Lamellipodium assembly 0.3683094292536917 0.0832258736348574 0.933671939917904 1.0 1.0 20 P05556,Q04656,P61160,O94813 4 +Receptor signaling pathway via stat 0.3531658557770594 0.082330480034371 0.934383917125844 1.0 1.0 14 P40763,Q6IA86 2 +Ribonucleoside metabolic process 0.33818440232274 0.0819640759201855 0.9346752805637928 1.0 1.0 9 Q13126 1 +Manganese ion transport 0.316410861865412 0.0812118580209296 0.9352734693304136 1.0 1.0 3 Q9HD20,Q9HC07 2 +Manganese ion transmembrane transport 0.316410861865412 0.0812118580209296 0.9352734693304136 1.0 1.0 3 Q9HD20,Q9HC07 2 +Positive regulation of neuron death 0.3649541566472745 0.0802161891231139 0.9360653145951524 1.0 1.0 19 Q15375,P17655 2 +Post golgi vesicle mediated transport 0.3956793788749725 0.0800175624221497 0.9362232879655994 1.0 1.0 47 O15126,O15027,Q99523,Q15334,P11279,Q8TAG9,O14828,Q9P2R3,P57737,Q92572,Q4J6C6 11 +Membrane docking 0.3885968614604553 0.0798500159142319 0.936356544341732 1.0 1.0 33 Q13277,O15400,P11234,P56545,Q13190,Q86Y82,Q96GC9,O43752 8 +Body morphogenesis 0.3332977125140498 0.0783044895274955 0.9375858463043396 1.0 1.0 8 Q15042,Q06124,O75787,Q7Z460 4 +Purine deoxyribonucleotide metabolic process 0.3188662533215298 0.0782447912792596 0.9376333329185262 1.0 1.0 4 Q9Y3Z3,P55263,P00491 3 +Cardiac cell development 0.3511424782810003 0.0773124928365704 0.9383749528080833 1.0 1.0 14 P11413,P78310,P06493 3 +Cellular response to mechanical stimulus 0.345243816842571 0.0769034460201242 0.938700356140618 1.0 1.0 12 P08069,Q9Y624 2 +Mrna alternative polyadenylation 0.3204370939161326 0.0735916883035542 0.9413352849792308 1.0 1.0 5 Q69YN4,Q96MU7,Q16630,Q8N684 4 +Hormone mediated signaling pathway 0.3925220761093668 0.0720061389742966 0.942597022340682 1.0 1.0 41 O95071,Q96HY6,Q9P1Z2,P46934,Q04917,Q15185,Q9GZZ9,Q06481,P42785,Q86X55 10 +Cell communication involved in cardiac conduction 0.339598432529165 0.0708317635125197 0.9435316516782336 1.0 1.0 11 P78310 1 +Positive regulation of plasma membrane bounded cell projection assembly 0.3805760920167432 0.0707054313111521 0.9436321980976624 1.0 1.0 29 Q5T0N5,Q15555,Q9UQ16,Q7L576,Q04656,Q9P2S5,P11233,Q16181,Q96C92,P61160 10 +Cytoskeleton dependent intracellular transport 0.3801856230146272 0.0705341413009485 0.9437685273802838 1.0 1.0 64 Q86VS8,Q8TD16,Q14254,O60313,P05067,Q9UH99,O95239,Q5T0N5,P60953,P11279,Q96BM9,O60333,Q14168,O75381,Q14203,Q9Y496,Q8NCM8,P43034,Q9UBF2,Q9UL25,Q92572,Q15154 22 +Regulation of cellular component size 0.3336206899442818 0.0701742330932991 0.9440549827671664 1.0 1.0 84 Q9NUQ9,Q15375,P15311,Q9NQ11,P51790,Q9UL25,P58546,Q7L576,P43034,Q04656,Q9UJU6,P61586,A0MZ66,Q96ST3,P51797,Q9UQB8,O15511,O94813 18 +Adp metabolic process 0.3843816237586411 0.0699003067668379 0.9442730089637446 1.0 1.0 32 P05067,P40763 2 +Positive regulation of neuron migration 0.3223043146417123 0.0696525500537306 0.9444702095744344 1.0 1.0 6 Q9Y263,A0MZ66 2 +Neural nucleus development 0.3632538254215984 0.0695375598416039 0.944561736566476 1.0 1.0 20 O15027,O95487,P60953,P62258,O75489,Q04917,P61586,Q16352,P11413,Q9UQR1 10 +Multicellular organismal signaling 0.3714802779052407 0.0690174382178651 0.9449757389065798 1.0 1.0 24 P62258,P20020,P04062,P43034,P14923,P15924,P05026,P78310,P23634,Q14126,O75844 11 +Regulation of lamellipodium organization 0.3580754630806521 0.0684199614607615 0.945451332115386 1.0 1.0 18 Q04656,O94813 2 +Glycosyl compound metabolic process 0.382627583665844 0.0683765200325763 0.9454859123767992 1.0 1.0 31 P04066,P06280,P08236,P04062,Q9BTY2 5 +Myeloid cell homeostasis 0.3918513479245311 0.0680265837013825 0.945764472562732 1.0 1.0 42 P04083,Q16539,P26583,O95251,P40763,Q7L5Y9,P11413,P36896,Q92542 9 +Negative regulation of macroautophagy 0.3441512217773304 0.067412443231663 0.9462533634574952 1.0 1.0 13 P31749 1 +Oocyte differentiation 0.3314606741573079 0.0670537830098426 0.9465388868552256 1.0 1.0 9 P35222,Q8N2A8,P30153,Q9H6S0,Q9BQA1,Q9Y2W6,Q15645,Q8IXJ6 8 +Histone h2a monoubiquitination 0.3169212515465215 0.0665720797245694 0.946922373573624 1.0 1.0 5 Q13620 1 +Protein localization to chromosome centromeric region 0.3426411451757618 0.0639217218396076 0.9490325561201683 1.0 1.0 13 P06493,O14777,Q96DY7 3 +Myeloid cell differentiation 0.3575782933226198 0.0634250333645376 0.9494280536361384 1.0 1.0 75 P21359,Q13619,Q15904,Q16539,P26583,P04062,P05067,Q9GZP4,O95251,Q9GZZ9,Q14739,P40763,Q7L5Y9,P11413,P36896,P02786 16 +Protein import into mitochondrial matrix 0.3294783153832279 0.0628370767616327 0.9498962412072258 1.0 1.0 9 O60830 1 +Negative regulation of cytokine production 0.3779280722968683 0.0626708233049457 0.9500286313365124 1.0 1.0 29 P49591,P04083,P15311,Q9UPY3,P04062,Q06481,Q07021 7 +Regulation of response to biotic stimulus 0.3754540828922618 0.062210830779719 0.9503949374831482 1.0 1.0 66 Q9NUD5,Q8IZ81,Q9BY67,Q7Z739,P11279,P26583,Q6UWE0,Q9Y4E8,Q06481,P01889,O75844,Q14671,Q9NZ08,Q07021,P04439 15 +Regulation of production of small rna involved in gene silencing by rna 0.3184638109305792 0.0619711341718707 0.9505858193979236 1.0 1.0 6 P17844,P04637,Q08209,O75844,P36507 5 +Epithelial cell development 0.386221384827081 0.0619031977721002 0.9506399209303312 1.0 1.0 36 P15291,Q9Y624,Q9UDY2,P31749 4 +Regulation of inflammatory response 0.3851890591244687 0.0616687970780663 0.9508265889809252 1.0 1.0 35 Q08722,P04083,P28070,P04062,P05067,P53634 6 +Homologous chromosome segregation 0.3288522067336683 0.0615222478826872 0.9509432967160224 1.0 1.0 9 P53350,Q92791,P46379 3 +Establishment of cell polarity 0.388633739094598 0.0598913026456083 0.9522422069449116 1.0 1.0 40 Q9NUQ9,P53350,P05556,P15311,Q15334,Q13308,Q14254,Q96N67,P43034,O14777,Q13464,P61586,A0MZ66,P08069,Q14203 15 +Sulfur compound transport 0.3239411364175275 0.0585223897403967 0.9533325286219344 1.0 1.0 8 Q9UBX3 1 +Histone h4 acetylation 0.3635204331813448 0.0584448166026131 0.9533943172716396 1.0 1.0 22 Q96L91,O95251 2 +Cardiac conduction 0.3514320269169654 0.0582335917754855 0.9535625637456976 1.0 1.0 17 P62258,P20020,P14923,P15924,P05026,P78310,P23634,Q14126,O75844 9 +Hepaticobiliary system development 0.3840763972594708 0.0580310342078254 0.9537239084494922 1.0 1.0 35 P21359,P04083,Q9BY67,Q04656,P11717 5 +Dendritic spine development 0.3712996670488276 0.0579319258796502 0.9538028526434172 1.0 1.0 26 Q14444,P61160,Q9UQB8,Q9UQ16 4 +Positive regulation of dna recombination 0.3745525205350087 0.057358775889118 0.9542594009831552 1.0 1.0 28 O96028,Q96L91,Q7Z4V5,P02786 4 +Sensory organ morphogenesis 0.3728162418847535 0.0572070460849624 0.9543802653903124 1.0 1.0 27 P21359,P54802,P40763 3 +Regulation of protein k63 linked ubiquitination 0.3157835424647435 0.056788964738804 0.9547133046151708 1.0 1.0 6 Q9Y263,O95071 2 +Response to platelet derived growth factor 0.3183380943818285 0.0545626144053129 0.9564869237495226 1.0 1.0 7 Q04656,P35241,P46940,Q96A49 4 +Negative regulation of ubiquitin dependent protein catabolic process 0.363863477292892 0.0536786121666758 0.9571912232479038 1.0 1.0 23 Q96HY6,P46379,P19784,Q9H2J4,O00560 5 +Protein targeting to peroxisome 0.3174543678193653 0.0528654077979427 0.957839146415222 1.0 1.0 7 P40855,P56589 2 +Tissue morphogenesis 0.3625091741835173 0.0527917000492776 0.9578978746816048 1.0 1.0 72 Q96AC1,P05556,Q15375,O60313,Q04656,P98164,Q9ULT8,P15311,Q13308,Q93074,P61586,O94813,Q8TAA9,P60953,Q9Y297,P62942,P15924,Q8N3R9,P09493,Q93063,P43034,P10644,P11233 23 +Response to acetylcholine 0.3134905322502209 0.0524718058055789 0.9581527600848534 1.0 1.0 6 P29992,P23634 2 +Exocytosis 0.3454824518550861 0.0514194212131913 0.9589913093526156 1.0 1.0 79 Q9UN37,P04083,O60645,Q13277,Q5JRA6,Q9NQ11,O15126,P11279,Q8TAG9,Q9Y3E7,Q7L0J3,P56545,Q5SQN1,Q92783,O00560,Q9BRK5,Q4J6C6 17 +Response to tumor necrosis factor 0.3852459526906541 0.0503974834168684 0.959805641782334 1.0 1.0 39 Q8TCT8,P04114,Q16539,P04062,Q13510,P31749 6 +Synaptic vesicle exocytosis 0.3533226261357229 0.0503317519576705 0.9598580214236708 1.0 1.0 19 Q5SQN1,Q7L0J3,Q13277,Q4J6C6 4 +Negative regulation of immune system process 0.387924797179868 0.0499874753712229 0.960132369050605 1.0 1.0 49 Q08722,P21359,P04083,Q16539,P28070,P10644,P31749,P01889,Q5JRA6,O94813,P04439 11 +Vesicle transport along microtubule 0.3299330715832952 0.0498579279199311 0.9602356042363268 1.0 1.0 11 Q9Y496 1 +Potassium ion transport 0.3551983009916297 0.0488855906132123 0.9610104721573832 1.0 1.0 20 P05556,P62258,P54709,P46934,Q9H4A3,P05026,Q9UHD1,P50570,P33176 9 +Viral translational termination reinitiation 0.3071470761961135 0.0483768448335284 0.961415912839762 1.0 1.0 5 Q14152,O75821,Q9Y262,P55884 4 +Female meiotic nuclear division 0.3219048924166944 0.0474792952433105 0.9621312317249068 1.0 1.0 9 O14777 1 +Cytokine mediated signaling pathway 0.3870862880976988 0.0473998545380014 0.9621945449534264 1.0 1.0 50 Q8TCT8,Q16739,P31749,Q06481,P40763,O94813,Q7Z739 7 +Spindle localization 0.349481925538083 0.047265405581247 0.9623016995994522 1.0 1.0 18 P53350,P05556,P43034,O14777,P61160,Q14203 6 +Protein exit from endoplasmic reticulum 0.3587347625941143 0.0460242312629193 0.9632909366154888 1.0 1.0 22 Q9NV96,Q9Y6B6,O15260,Q92544 4 +Pyrimidine nucleoside triphosphate biosynthetic process 0.3209243816052943 0.0455779292288791 0.9636466608109656 1.0 1.0 9 P15531,P17812,O75414 3 +Regulation of plasma lipoprotein particle levels 0.3430441918225628 0.0450196682152853 0.964091631878432 1.0 1.0 16 P38571,P04114,Q8WTV0,Q9H4M9 4 +Exocytic process 0.3530524101731548 0.0436264345814718 0.9652021800046238 1.0 1.0 20 Q5SQN1,Q7L0J3,Q13277,P56545 4 +Regulation of neuron projection arborization 0.2954545454545513 0.0433699333877762 0.9654066448216904 1.0 1.0 3 Q9HCE1,Q15334 2 +Purine ribonucleotide salvage 0.3041937389249948 0.0432581992494085 0.9654957121763594 1.0 1.0 5 P07741,P55263,P00492,P00813 4 +Amp salvage 0.3041937389249948 0.0432581992494085 0.9654957121763594 1.0 1.0 5 P07741,P55263,P00492,P00813 4 +Purine nucleotide salvage 0.3041937389249948 0.0432581992494085 0.9654957121763594 1.0 1.0 5 P07741,P55263,P00492,P00813 4 +Cardiac muscle cell action potential 0.3363050988045053 0.0431784592394158 0.9655592761083472 1.0 1.0 14 Q14126,P78310 2 +Negative regulation of protein catabolic process 0.3843939010729773 0.0412587844626844 0.9670895903065726 1.0 1.0 42 Q9NQ11,P10619,Q96HY6,Q9GZU8,P46379,P19784,Q9H2J4,O00560 8 +Transport along microtubule 0.3834599424633296 0.0412547926193613 0.9670927726272264 1.0 1.0 55 O95239,Q9Y496,Q8TD16,P60953,Q8NCM8,Q14254,O60313,P11279,Q96BM9,P05067,P43034,Q15154,O60333,Q9UBF2,Q14168,Q9UL25,Q92572,Q14203 18 +Microtubule based transport 0.3834599424633296 0.0412547926193613 0.9670927726272264 1.0 1.0 55 O95239,Q9Y496,Q8TD16,P60953,Q8NCM8,Q14254,O60313,P11279,Q96BM9,P05067,P43034,Q15154,O60333,Q9UBF2,Q14168,Q9UL25,Q92572,Q14203 18 +Thioester biosynthetic process 0.3611664585123109 0.0410788934355961 0.9672330009965358 1.0 1.0 24 Q9UMR5 1 +Epidermis development 0.3856901617317304 0.0409460352620538 0.9673389173675906 1.0 1.0 48 P21359,P04083,Q16739,Q14254,Q04656,Q13247,Q13510,Q13464,Q8NEY8,P67809,P43034,P51648,P29375,O75844,P36896 15 +Regulation of transcription regulatory region dna binding 0.3243828707488673 0.0387006159807866 0.9691290822970852 1.0 1.0 11 Q00403,Q96ST3,O75844 3 +Positive regulation of interferon beta production 0.3242059900978362 0.0383556499530515 0.9694041211512998 1.0 1.0 11 P41440,O75955 2 +Actin filament based transport 0.3126623804855317 0.0370768996907118 0.9704236907376388 1.0 1.0 8 Q5T0N5,Q9UH99 2 +Positive regulation of gtpase activity 0.3812388184083287 0.0369697717439248 0.9705091079104748 1.0 1.0 39 P21359,Q96AC1,P05556,Q8IZ81,Q15555,P23229,P31751,Q96N67,Q9Y3P9,Q9Y624 10 +Negative regulation of muscle tissue development 0.2958446519628471 0.0367922030211406 0.970650690928806 1.0 1.0 4 P16989 1 +Negative regulation of muscle organ development 0.2958446519628471 0.0367922030211406 0.970650690928806 1.0 1.0 4 P16989 1 +Nucleotide salvage 0.3042836041358969 0.0362096932960984 0.9711151569268044 1.0 1.0 6 P55263,P00492,P00813,Q9BZX2,P07741 5 +Regulation of dna methylation dependent heterochromatin assembly 0.3082241263958345 0.0360908023426823 0.9712099562188832 1.0 1.0 7 Q8NEY8 1 +Negative regulation of protein binding 0.368551573077543 0.0355359461147822 0.971652383611727 1.0 1.0 29 O95816,Q9UBB9,Q9GZU8,P31749,P10586 5 +Protein polyufmylation 0.2991366105627826 0.0348972727355269 0.972161655332012 1.0 1.0 5 Q9GZZ9 1 +Reticulophagy 0.2991366105627826 0.0348972727355269 0.972161655332012 1.0 1.0 5 Q9GZZ9 1 +Positive regulation of establishment of protein localization to telomere 0.3185448092280428 0.0342889608166764 0.9726467276867952 1.0 1.0 10 P50991,Q9BUR4,Q99832,P17987,P49368,P40227,P78371,P48643,O60832 9 +Regulation of establishment of protein localization to chromosome 0.3185448092280428 0.0342889608166764 0.9726467276867952 1.0 1.0 10 P50991,Q9BUR4,Q99832,P17987,P49368,P40227,P78371,P48643,O60832 9 +Establishment of protein localization to telomere 0.3185448092280428 0.0342889608166764 0.9726467276867952 1.0 1.0 10 P50991,Q9BUR4,Q99832,P17987,P49368,P40227,P78371,P48643,O60832 9 +Negative regulation of mrna metabolic process 0.3836234629317889 0.03324251653678 0.9734811935500568 1.0 1.0 49 Q16539,P18615,P67809,Q5VTR2,P26368,Q07021 6 +Detection of visible light 0.3023043871727937 0.0329360884200798 0.9737255540004224 1.0 1.0 6 Q15555 1 +Synaptic vesicle localization 0.3280349914166578 0.0326585411462822 0.973946885613143 1.0 1.0 13 Q92572 1 +Regulation of neurotransmitter transport 0.3341151133832661 0.0320860622220693 0.9744034184238306 1.0 1.0 15 P21359,P05556,O75955,Q4J6C6 4 +Maintenance of location 0.3626806721180106 0.0317740525902344 0.974652239218596 1.0 1.0 70 O43292,P04114,Q9C0B1,P35670,O43731,P06756,P17900,P04062,Q8WTV0,Q9UH99,P62942,P07686,Q9H4M9,P31749,P31946,P10253 16 +Vitamin metabolic process 0.3703579553530627 0.0316256188444918 0.974770612722015 1.0 1.0 31 P00374,P41440,Q99538,Q9Y4U1,P04062,P98164,P34896 7 +Positive regulation of mitochondrial fission 0.3094583253399041 0.0314593455860822 0.9749032136070328 1.0 1.0 8 Q96HS1 1 +Response to testosterone 0.3198420469698638 0.0300515332509336 0.9760259541170252 1.0 1.0 11 P08069,P04062 2 +Mitotic cell cycle phase transition 0.2588310092700852 0.0296028563305791 0.9763837872909484 1.0 1.0 135 P05556,P49321,P05067,Q9H1A4,Q96ST3,Q06481,O60921,P08183,Q13564,Q9P258,Q13619,Q9UJX4,Q13620,P36896,Q96DY7,P04083,P53350,Q7LG56,O14777,P06493,Q8WUX9,Q9UHI8,Q9UJX5,Q9NXR7,Q13616,P31749,O60934,Q9UN37 28 +Fructose 6 phosphate metabolic process 0.3037825059101717 0.0286328285718535 0.9771574293975946 1.0 1.0 7 P08237,P17858,P19367,P52789,Q01813,Q06210 6 +Regulation of neuron migration 0.3076884743269659 0.0284454848932373 0.9773068471645658 1.0 1.0 8 P40763,A0MZ66 2 +Regulation of ruffle assembly 0.3076314597897079 0.0283494461783515 0.9773834440816642 1.0 1.0 8 P35241,Q7L576,Q9P258,P35080 4 +Protein stabilization 0.3580136623880032 0.0276388104869091 0.9779502271869798 1.0 1.0 72 O15027,P41440,O95816,P13473,P54709,P11279,Q32P28,O75955,P40855,P46379,Q15185,O95785,Q86Y82,Q9H2J4,Q99747,Q9UL25,Q9UNS2 17 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.3619331377393632 0.0273733881526171 0.9781619234706638 1.0 1.0 27 Q96HY6,Q9GZU8,P46379,P19784,Q9H2J4,O00560 6 +Morphogenesis of embryonic epithelium 0.3578033613203399 0.0271152686947687 0.9783677965811616 1.0 1.0 25 P98164 1 +Cytoplasmic translational initiation 0.3432368389321661 0.0268293639063176 0.978595832633081 1.0 1.0 19 P41214,P55010,Q15056,Q9BWF3,Q9NR50,Q9ULC4,P23588 7 +Chaperone cofactor dependent protein refolding 0.3343666974530523 0.0262790811219135 0.979034739995358 1.0 1.0 16 P48723 1 +Regulation of neurotransmitter levels 0.3737351576635668 0.0256731470192117 0.9795180423696744 1.0 1.0 35 P21359,P05556,Q13277,Q7L0J3,P56545,O75955,Q5SQN1,P50897,Q4J6C6 9 +Cellular senescence 0.3424880336786733 0.0251742847793043 0.9799159482276816 1.0 1.0 19 P08069,O75844,Q16539,P67809 4 +Embryonic organ morphogenesis 0.3442851985871127 0.0232054819819839 0.9814863657968682 1.0 1.0 20 P54802 1 +Cotranslational protein targeting to membrane 0.3293264688117948 0.0223857965202304 0.9821402102488972 1.0 1.0 15 Q9H173 1 +Pentose phosphate shunt 0.303872302689921 0.0221613079140426 0.9823192818162664 1.0 1.0 8 P18669,Q9NQ88,P29401,P52209,P04637,P11413,O95336 7 +Myoblast differentiation 0.3037328449088124 0.0219371772123891 0.9824980687767132 1.0 1.0 8 P05556,Q16539 2 +Detection of stimulus 0.3402847235456182 0.0203763615663809 0.983743140672759 1.0 1.0 19 Q15555,Q9BY67,P19022,Q8WTV0,P01889,P04439 6 +Regulation of lipid metabolic process 0.3771011752856052 0.0199380289165404 0.9840928084793436 1.0 1.0 57 Q9UBM7,P04083,P04114,Q9BZK7,P07602,P31751,Q8TBX8,Q8WTV0,Q13510,Q96N66,P31749,P61916,Q06481,P17655 14 +Negative regulation of protein serine threonine kinase activity 0.3477354196420227 0.0194344937599155 0.9844944935585492 1.0 1.0 22 P21359,P04062,P31749 3 +Pigment granule maturation 0.2786304604486496 0.0192182152927873 0.984667026583729 1.0 1.0 3 Q9BXS5,O14617 2 +Pigment accumulation 0.2786304604486496 0.0192182152927873 0.984667026583729 1.0 1.0 3 Q9BXS5,O14617 2 +Negative regulation of muscle cell differentiation 0.3099196475635717 0.0190573931051161 0.984795320627814 1.0 1.0 10 P11413,P67809 2 +Negative regulation of blood circulation 0.2777449822904443 0.0180942596499785 0.9855636573388908 1.0 1.0 3 P05023,P30626 2 +Embryonic organ development 0.3791733305545357 0.0177376250349078 0.9858481649261684 1.0 1.0 46 P42892,P54802,P31749 3 +Cardiac neural crest cell differentiation involved in heart development 0.2768595041322381 0.0169846004072548 0.9864489010960492 1.0 1.0 3 P27361,P60953 2 +Caveolin mediated endocytosis 0.2768595041322378 0.0169846004072545 0.9864489010960492 1.0 1.0 3 Q9UNF0,P27361 2 +Regulation of tor signaling 0.3291638123974896 0.0158238850036794 0.9873748933438148 1.0 1.0 16 O75844,P04062,Q9H4H8 3 +Positive regulation of telomerase rna localization to cajal body 0.3188277087033682 0.0152727703723778 0.9878145660450408 1.0 1.0 13 P50991,Q99832,P17987,Q9Y265,Q9NPE3,P40227,P78371,P49368,P48643,Q9NX24,O60832,Q9Y230 12 +Segmentation 0.3151875779882326 0.0152018522009583 0.9878711439906928 1.0 1.0 12 Q93074 1 +Ruffle organization 0.3254208394197371 0.0148377664160992 0.9881616096500352 1.0 1.0 15 P09493,Q7L576,Q9UJU6 3 +Platelet activation 0.3282979832606638 0.0141406169884239 0.9887177960186648 1.0 1.0 16 Q9Y624,Q9BWH2 2 +Positive regulation of binding 0.3771987542888314 0.0131796646158538 0.9894844535186404 1.0 1.0 54 P41440,P26583,P62942,P05067,P56545,O75503,O75955,Q96D46,Q00403,Q07954 10 +Protein ufmylation 0.2889052293805384 0.0127960133589924 0.9897905371145604 1.0 1.0 6 Q9GZZ9 1 +Pigment granule organization 0.2787127251254857 0.0126862585072028 0.9898781017084772 1.0 1.0 4 Q9BXS5,O00203,O14617 3 +Intracellular lipid transport 0.327359687394982 0.0123346486066746 0.9901586238647656 1.0 1.0 16 P61916,O15118 2 +N terminal protein amino acid modification 0.3056530319217856 0.0120827646548324 0.9903595832032176 1.0 1.0 10 P41227,Q86UY6,P50579 3 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3127569605080562 0.0110382095367079 0.9911929618767426 1.0 1.0 12 P67809 1 +Biological process involved in interaction with symbiont 0.3554139862694673 0.0108334572537993 0.9913563207932404 1.0 1.0 27 P11717 1 +Fatty acid transport 0.3357239305285909 0.010786069080671 0.9913941288759204 1.0 1.0 19 P04083,P31749 2 +Cardiac muscle contraction 0.3352656324275923 0.00984777826716 0.9921427367605388 1.0 1.0 19 Q14126,P10253 2 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.2989708878866955 0.0081478565066829 0.9934990230204328 1.0 1.0 9 Q9UNN5 1 +Negative regulation of histone modification 0.3313188161034232 0.0078847575321666 0.9937089388847282 1.0 1.0 18 P29375,O95071,Q01105,Q96ST3,Q6W2J9 5 +Dna methylation 0.33082333593344 0.0069118097786662 0.9944852176001526 1.0 1.0 18 Q9H9B1,O95983,Q8NB78,O75844,Q9Y2W6,O14744,P26358 7 +Dna methylation dependent heterochromatin assembly 0.3019421790775278 0.0063133185236281 0.9949627340851384 1.0 1.0 10 Q9NRZ9,P26358,O95983,Q8NEY8 4 +Activation of phospholipase d activity 0.2674144037780467 0.0060191896849491 0.9951974104820048 1.0 1.0 3 Q14344,P18085 2 +Heart process 0.3641414855140978 0.0058996950357014 0.9952927517246466 1.0 1.0 33 P09493,Q93063,P78310,Q14126,P10253 5 +Epithelial tube morphogenesis 0.3704199356201076 0.0057721954723744 0.995394479925308 1.0 1.0 38 P98164,Q15375,O94813 3 +Blastocyst growth 0.2970780929186797 0.0053720567039774 0.9957137395123424 1.0 1.0 9 O60934 1 +Microtubule organizing center localization 0.3166796465222403 0.0052397823781624 0.9958192776690172 1.0 1.0 14 P15311,Q8TD16,Q9UH99,O15511 4 +Camera type eye development 0.3688286917582835 0.0042681680555044 0.9965945049454016 1.0 1.0 37 P21359,Q15555,P20020,O15078,Q99471,Q16706,P54802,P23634,Q99797 9 +Regulation of establishment of protein localization to mitochondrion 0.3195629939286649 0.0041247345392882 0.9967089473257128 1.0 1.0 15 P68036,Q9UBE0,O43464,P19784,P55786,Q9Y371 6 +Cytoplasmic pattern recognition receptor signaling pathway 0.3291240013500652 0.0036155327897688 0.997115228492961 1.0 1.0 18 Q14671,Q9NUD5,Q07021 3 +Glucose 6 phosphate metabolic process 0.3041420118343249 0.0034217772255571 0.9972698221089638 1.0 1.0 11 P18669,Q9NQ88,P19367,P29401,P52209,P52789,P04637,P06744,P11413,O95336 10 +Cellular response to fatty acid 0.2755463673951649 0.0024070242347389 0.9980794743801362 1.0 1.0 5 Q96GM5,P50416,P13010,P11802 4 +Negative regulation of extrinsic apoptotic signaling pathway 0.3344292105349252 0.0022956364155718 0.9981683487555826 1.0 1.0 20 P06756,P23229,P31749 3 +Nuclear migration 0.3144092364860246 0.001374152546147 0.9989035852443005 1.0 1.0 14 Q86VS8,Q96N67,P43034,Q9UH99,Q15154,Q14203 6 +Intraciliary transport involved in cilium assembly 0.2628760980803798 0.0012995794102546 0.9989630859448956 1.0 1.0 3 Q15154 1 +Nucleotide transport 0.3177748083882227 0.0009986275349896 0.9992032106402732 1.0 1.0 15 Q08722,P41440 2 +Negative regulation of nuclear division 0.3362838355425271 0.000307714548368 0.9997544793165972 1.0 1.0 21 O75414,O14777,Q96DY7 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4e2526572dbf9be9cb0fd6aa4f632771c4ff2a02 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chitin metabolic process", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Elastic fiber assembly", "Elastin metabolic process", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindgut development", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene d4 metabolic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein particle remodeling", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Nodal signaling pathway", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Norepinephrine metabolic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyamine transmembrane transport", "Polyamine transport", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of leukocyte tethering or rolling", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage derived foam cell differentiation", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prostate glandular acinus development", "Prostate glandular acinus morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein lipoylation", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein sialylation", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in prostate gland morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of leukocyte tethering or rolling", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell division", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Sialylation", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCS1L", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf29", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C20orf27", "C2CD2L", "C2CD5", "C3orf58", "C5orf51", "C9orf64", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC85C", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPO", "CENPP", "CENPV", "CEP135", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COASY", "COG3", "COG4", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMADHC", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PAXX", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF23", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RMND1", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TACC3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM63A", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WRAP53", "WRAP73", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "AAR2", "AARS", "AATF", "ABCB1", "ACOT7", "ACOT8", "ACP2", "ACTN1", "ACTN4", "ACTR2", "ACVR1B", "ADA", "ADAMTS1", "ADK", "AIFM1", "AKAP12", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALDH1A2", "ALDH3A2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANP32B", "ANP32E", "ANXA1", "AP1M1", "AP3B1", "AP3D1", "AP3S1", "APEX1", "API5", "APLP2", "APOB", "APOBEC3C", "APP", "APRT", "ARF4", "ARF5", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARIH1", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC9", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ATG3", "ATG7", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG6", "BAIAP2", "BAZ1B", "BCOR", "BICD2", "BLMH", "BRCA1", "BSG", "BTRC", "BUB1B", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C3orf58", "CADM1", "CALCOCO1", "CALD1", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CBFB", "CBX3", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CD2AP", "CD47", "CDC25C", "CDC42", "CDC73", "CDH2", "CDK1", "CDK4", "CDK5RAP3", "CEP290", "CERS2", "CFAP20", "CHAC2", "CHMP3", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST12", "CHST14", "CHTF8", "CHUK", "CKAP2", "CKB", "CLASP1", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLN6", "CLUH", "CMAS", "CMPK1", "CNNM4", "CNPY2", "COG4", "COG6", "COG8", "COLEC12", "COPA", "COPB2", "COPE", "COPG2", "COPS3", "COPS4", "COPS7A", "CORO7", "COTL1", "COX15", "COX2", "COX7A2", "CPD", "CPNE1", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPVL", "CREG1", "CSNK2A2", "CSNK2B", "CSRP2", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTNBP2NL", "CUL1", "CUL3", "CUL4A", "CUL4B", "CUTA", "CUX1", "CXADR", "CYB5D2", "CYFIP1", "DAGLB", "DAPK3", "DBN1", "DBNL", "DCTN1", "DCTN2", "DCUN1D5", "DDRGK1", "DDX1", "DDX20", "DDX3X", "DDX5", "DDX56", "DDX6", "DERL1", "DHCR24", "DHCR7", "DHFR", 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sha256:ea06da00786bc7466a60ac47652af4cb1d7f788aaa27be0952dc29dd937f63f3 +size 181484 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0d11442287543677f55d027784a3c01516ff8f6d --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,58 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Vacuole 84 234 6.697446727323501 2.120925078601601e-11 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 1.8893460131157977e-22 2.25345657147112e-16 1.0533920074133077e-29 1.8272152481684163e-31 2.0854043969078167e-25 +Golgi apparatus 89 348 5.985373656914157 2.158936526275958e-09 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 8.080307296510154e-08 1.4952468522532928e-05 2.2959178775947715e-09 2.0478651637753368e-15 2.525097184133674e-10 +Secretory vesicle 69 284 5.750323553927877 8.907282035103375e-09 56.25485436893204 257.47087378640776 0.1341228551105892 0.6386901443364594 16.601865631745117 19.12774191814033 1.3029114519128766 0.3900514633935764 6.06396552664993e-14 5.527892209332889e-08 1.0558583113437556e-17 4.3057136447122377e-19 3.260960007238378e-17 +Secretory granule 65 257 5.733758584820721 9.82291201887216e-09 49.29854368932039 231.6504854368932 0.0742534337219474 0.6450440279734955 14.609170474630965 16.529443419678444 1.2643241567239918 0.3828342632667716 8.116114817932507e-14 4.885321799881838e-09 4.675336221156174e-18 1.87554348966458e-20 2.42416008694226e-18 +Endosome 67 239 5.411064932580003 6.265104784151656e-08 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 3.2572824864775965e-08 8.422505754572417e-08 7.85779894151094e-10 1.6726434840844463e-11 1.293379533413865e-11 +Vesicle membrane 81 275 5.168733895847431 2.3568519433637e-07 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 2.2946873823635417e-07 1.2404547857476872e-05 1.8454963334525535e-09 7.338954203744431e-12 1.0113004906719654e-14 +Vacuolar membrane 45 134 4.77006673855673 1.8416489275807637e-06 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 2.522439224270304e-07 3.201030413891611e-05 4.5252294023293017e-11 4.286681407454968e-14 2.324197716452678e-13 +Early endosome 33 110 4.674997025640154 2.9395787990438293e-06 24.66504854368932 96.93203883495146 0.530758374709677 0.5743319290889299 8.086272783051246 14.025470683081796 1.1449007118883376 0.3721207721610414 5.965172560470772e-05 0.0004142619301678 1.5447664149484008e-05 3.544280161649626e-07 2.729137058967065e-07 +Vesicle lumen 27 133 4.651255947416265 3.299195528772003e-06 28.93446601941747 119.79368932038837 -0.0708316930912348 0.5682496130595786 13.122391611595372 7.240907185867801 1.2978103845669404 0.3622974798457447 3.9946134061829874e-08 5.23641986489469e-06 6.791325753999263e-10 9.754083387312772e-11 3.3405378876110306e-08 +Golgi membrane 34 146 4.4264184230269095 9.581059208452205e-06 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.0004056308906611 0.0170554111715972 5.109386026831788e-05 7.279931420980524e-10 1.871858379154769e-05 +Endosome membrane 46 139 4.101007333020056 4.113555227513999e-05 28.436893203883496 125.75485436893204 0.1968108610887141 0.5657595498250074 10.058247741499075 16.477863960688197 1.2734596099850304 0.3756178998455078 0.0001616022596934 0.002437222738378 1.571240901839746e-05 1.231180046071335e-08 3.13800627720162e-10 +Perinuclear region of cytoplasm 43 192 3.970451813031656 7.173646432212522e-05 41.351941747572816 185.873786407767 0.188099869779145 0.7574745839917925 13.945452720131469 19.27429981182019 0.8259268596181808 0.3356085544002479 0.005191153240747 0.000650700111479 0.0030431577495135 0.002585232645593 4.504787310852708e-06 +Golgi apparatus subcompartment 24 103 3.815040487018337 0.0001361606074623 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0012004528556937 0.0105180668116997 0.0002823001683425 7.911767758493846e-07 5.85866351918042e-05 +Transport vesicle 27 101 3.781680560848732 0.0001557731734009 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 0.0008983130459351 0.0385478696321071 0.0008872587418106 3.664317463561458e-07 3.406516141881096e-06 +Vacuolar lumen 38 73 3.746712970263623 0.0001791668962149 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 9.848845628418811e-29 8.370543104559474e-20 2.5260760529109424e-34 3.3861947059300784e-36 2.1410351321166627e-26 +Plasma membrane region 48 200 3.650680410002095 0.0002615465198139 37.73300970873787 182.8543689320388 -0.0429858755806595 0.7440980541057753 13.808910085078033 20.71988762151849 0.7765309094582562 0.3262858205975006 0.1025780195052827 0.029308484958842 0.0706760058889804 0.0041235191030459 0.0002062017789162 +Endocytic vesicle 27 93 3.5721682094501706 0.0003540378816735 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 0.0001728944578064 5.8425231265747e-06 3.845449805720278e-06 1.1107387738054417e-07 4.708270633864456e-08 +Cell surface 36 87 3.5156978386022777 0.0004385998456903 21.233009708737864 77.5995145631068 0.4772545566224628 0.498248600191797 7.455308766626032 8.832436895439663 1.3320096182828691 0.3812427248674431 1.0993530556456721e-07 2.617336989032139e-07 2.876587777550066e-07 2.581612936048592e-09 1.7480521640725325e-07 +Azurophil granule 33 76 3.4588328810763587 0.0005425214113814 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 1.6202824021185684e-13 3.6634345647094172e-09 1.1715020020915238e-21 1.4550501323074576e-25 3.687244051307034e-21 +Coated vesicle 28 96 3.422022667367389 0.0006215713143289 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 2.347784768684985e-05 5.23641986489469e-06 2.197434324659721e-05 4.130708185790735e-07 1.2093011522110702e-07 +Endoplasmic reticulum 105 516 3.272768241519762 0.0010649976351524 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 0.0002680072732341 0.0046820176289524 5.4344311033311296e-05 6.1566728242619e-09 4.078430365899364e-08 +Somatodendritic compartment 37 154 3.230166479965437 0.0012371815549434 31.432038834951456 140.1868932038835 -0.1387544521782559 0.7574003462776103 12.326179524426648 14.394292391590982 0.571616894026409 0.2818454068652689 0.0674986295868153 0.1917966827028815 0.1582655618876189 0.2397713935730418 0.0280746228056074 +Intrinsic component of plasma membrane 43 92 3.1253847891854627 0.0017757261316853 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.0031137687860209 7.263995736860661e-05 0.0005039927583347 2.514823212834575e-05 1.6625215401962977e-05 +Neuron projection 54 236 3.04505145118992 0.0023264050773861 47.172330097087375 216.88834951456312 -0.1996653364583252 0.7561135872106907 15.819120524931153 25.56587076086662 0.562382950706032 0.2885861904290195 0.0579218955016424 0.2940962324258824 0.0961509122208981 0.339839897738082 0.0324442431382317 +Lysosomal lumen 33 42 3.008143137150979 0.0026284930486015 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 3.7519540003605035e-29 6.478201885300011e-20 2.6254474000473147e-34 1.8504894487205801e-37 4.346929167707939e-27 +Dendritic tree 28 118 3.0033150198758927 0.0026705584118686 22.95873786407767 107.45145631067962 -0.0089298880544856 0.7901437474135781 9.15114435834159 11.344776515640968 0.5591604100280799 0.2700884124193979 0.0501776450986962 0.0873922887467231 0.1133582198936705 0.3273453000019224 0.0742015897358769 +Axon 40 132 2.8133575241230213 0.0049027107077641 28.50485436893204 123.48300970873788 -0.1480614837947368 0.66370704402985 11.910975428503043 14.062178243823778 0.8082077724464304 0.3284972271669918 0.0813789422631467 0.1232635861837573 0.0811687836046556 0.3508214028085505 0.0244486326893572 +Golgi lumen 3 5 2.741060104010538 0.0061241303763277 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.025301964499895 0.1457663642848915 0.0376249374527164 0.0071928662194731 0.0674365169251515 +Endosome lumen 5 7 2.7165451925387547 0.0065967188407771 1.604368932038835 3.8932038834951457 0.8845546079995737 0.2641736972645504 1.2526788149416888 1.4642180149570363 1.3478975321629194 0.2569719391794136 3.477716107284155e-07 3.3882224489623025e-08 1.0236679094826864e-06 5.674616226795717e-06 0.0002747300414667 +Cell leading edge 33 119 2.713348031571348 0.0066607111114258 28.808252427184467 114.44174757281552 -0.1991917740572248 0.672044075129004 11.981767291657192 11.69636093329509 0.7227206919436855 0.3024789588236066 0.2492374987281794 0.2168603055746994 0.3875890149934164 0.4042211624765466 0.0169304057641362 +Nuclear envelope lumen 1 5 2.666025155507738 0.0076753949520189 1.5922330097087378 4.730582524271845 0.2740214243637495 0.4274662744917171 1.0138544466097483 0.5098416377826835 1.1584731829510644 0.3162624936844113 0.0008714317385846 0.0003491251705821 0.0013376518177504 0.0082857576662697 0.0309764532364539 +Secretory granule membrane 27 81 2.6377090135203547 0.0083468170223874 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.0004886131350085 0.0117205067001905 1.1938841481928453e-06 1.4727622518105572e-08 2.739213178749533e-09 +Cell body 22 109 2.6256782759532773 0.008647651071822 23.62135922330097 100.2135922330097 -0.2261944565190333 0.6872969325098738 10.154024028815115 9.144365855634126 0.6450340442422253 0.288113363632936 0.2045782079615987 0.7773072299471677 0.3283027140982518 0.1169586185816875 0.0601281318509707 +Ficolin 1 rich granule 18 94 2.62368588275165 0.008698396596056 23.65776699029126 87.40776699029126 -0.2227524879803391 0.5328920793977936 13.237445521916472 3.951617324550425 1.218029306074882 0.3604375114796861 0.0042712860874881 0.4949062745628336 0.0003547193570294 0.0001328066461469 3.623116133612819e-05 +Side of membrane 35 85 2.5564261257971097 0.0105753523664229 17.526699029126213 71.19660194174757 0.4235531336200628 0.5236659753791312 6.9409272887607125 8.635706418493163 1.198097658489356 0.36822581052137 0.0001239561832076 0.0012901179563887 2.5382317150385407e-05 1.0135711918594316e-05 1.2455665844288766e-06 +Intrinsic component of organelle membrane 33 140 2.5171869220130194 0.0118296051122552 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 0.2045782079615987 0.4369125326883025 0.0696200653310784 4.010536902061515e-06 3.5562835331804807e-06 +Chloride channel complex 1 5 2.4885150365193898 0.0128277812590531 1.6310679611650485 5.075242718446602 0.2943428743278045 0.4119582773335843 1.172005925149341 1.1561018739840807 1.1032422410077494 0.2897431462530468 0.0037203118650809 0.0015075035399645 0.0056684159955205 0.0331187861076589 0.018020673376298 +Azurophil granule lumen 18 45 2.3837032738256982 0.0171394158390194 12.118932038834952 41.25728155339806 -0.033426136567579 0.3776020138210581 4.31782609196223 3.0753988435553 1.7699755963815147 0.3570217435028845 3.9826846662666093e-11 1.9801996322951282e-08 1.8578257135301317e-14 4.680717154408744e-15 6.978543363124023e-12 +Cornified envelope 2 6 2.3233738872541827 0.0201590756535536 2.8009708737864076 6.174757281553398 -0.5812594468841538 0.3710659014759411 1.5576927888368688 0.8294012867640211 1.2675404526303018 0.3201867149657243 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.0062969264366488 0.0397387250697101 +Integral component of synaptic vesicle membrane 3 5 2.2947485901569293 0.0217475364105064 2.2475728155339807 4.910194174757281 0.8567274645780141 0.3149754325120096 1.3818760752746044 1.4445051429216968 1.1133243513780926 0.2989777184888048 0.1239529915803282 1.0 0.1515272625734178 0.0630532374058985 0.0078812527225172 +Presynapse 26 98 2.292517955071907 0.0218757726714902 22.813106796116504 90.997572815534 0.4365135448276876 0.6534842370695999 7.919284748658944 8.50627945845188 0.826940228235506 0.3445781590237917 0.0682156257794006 0.4061443456431609 0.0548518101793216 0.0437586510834369 0.0055370136721694 +Organelle subcompartment 81 410 2.281632163179571 0.0225110661704064 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 0.0071520939263942 0.0998366509246076 0.0008236613658022 1.3810292668868823e-06 5.064489536711375e-06 +Desmosome 2 7 2.257565816221852 0.0239727418530233 3.3106796116504853 6.434466019417476 -0.9067356401145186 0.322772712277776 1.496138240676771 0.8579024184165305 1.1482508166012304 0.3043884185116927 0.1307520596304716 0.0847528009868792 0.1596960736798767 0.0088528623379573 0.0539281835546241 +Clathrin coated endocytic vesicle membrane 6 16 2.248972942305411 0.0245142175950592 3.796116504854369 13.682038834951456 0.0573666642471241 0.400612365903674 2.3816010903207343 1.646817383208435 1.3652035545006669 0.3297171871883064 6.64941927775123e-06 6.712990966849457e-07 1.9121858527291338e-05 0.0001749771036996 0.0012514150662819 +Azurophil granule membrane 11 25 2.2340810674438374 0.0254777394870397 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0053489875931027 0.2027885470531376 2.404645312880536e-07 6.14722912539873e-10 1.9245529128315722e-08 +Early phagosome 0 5 2.19853830455327 0.0279107680159451 1.3228155339805825 3.133495145631068 -0.0099439284177487 0.5628884374552341 1.002503582034351 0.8725280853274426 1.0176397296822668 0.3315606249787017 0.0676363609296167 0.0432957136582515 0.0832836732680532 0.1988473022417859 0.361145714490569 +Endolysosome 1 10 2.1572335449859894 0.0309874719881688 3.3810679611650487 8.798543689320388 -0.4980552085105273 0.4508748211144175 2.1526526479127432 1.5874806980048122 1.0027139446036482 0.3093335090902263 0.0093067293886875 0.0038211367015083 0.014058804472369 0.0768284795296569 0.2348875720984273 +Endocytic vesicle membrane 19 48 2.147506269874048 0.0317529985749198 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 2.558975348497767e-05 6.462712020175136e-08 1.1577347646019884e-07 1.2523239066990288e-08 1.8601422222426145e-08 +Proteasome core complex beta subunit complex 6 7 2.1342527995170304 0.0328220927389082 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0676363609296167 1.0 0.0832836732680532 3.9104524570814734e-05 2.8311070051942505e-05 +Cell cell junction 40 117 2.0704772850145616 0.038407671044262 26.053398058252423 108.90776699029126 -0.2569312511624391 0.6234868006154447 10.868903853538864 10.886494611057328 0.8320790781958789 0.3243713173268808 0.2274393853683116 0.4602690207748234 0.359038933128316 0.0217791267832796 0.0870956667279223 +Clathrin coated endocytic vesicle 6 21 2.060760392156681 0.0393259048856895 4.774271844660194 18.74271844660194 -0.0983362729934113 0.4816370533307881 3.136849294900222 2.1033538609603957 1.2416005860349415 0.3436375292109884 2.3556180150196565e-05 2.4350782386469327e-06 6.670129789082706e-05 0.0007167071983955 0.0055591316089767 +External side of plasma membrane 16 28 2.057581551948101 0.0396303190511264 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 1.6862667322116276e-05 0.0001613707598744 7.591474537533828e-06 5.1129448205325154e-05 2.9859829576381497e-06 +Anchoring junction 62 258 2.0276484880682744 0.04259613649832 70.35436893203884 249.65533980582524 -0.627357170232948 0.5594712122092302 23.868687196518547 18.499216609786323 0.7982987681883342 0.3308050417452688 0.0935000076864488 0.1709065821367653 0.1239372390593913 0.0364439099240928 0.0568901108316337 +Glial cell projection 1 5 1.981371267983436 0.0475496534325612 1.4271844660194175 4.439320388349515 0.5256630412856145 0.4795278875555782 1.093688350806908 0.8638969757615467 0.9368809323777078 0.3221784257132529 0.1101969479300293 0.0711332726649859 0.1349531130589082 0.3090006421698555 0.1630814235328921 +Unconventional myosin complex 1 5 1.9742772934231485 0.0483502213394992 2.1067961165048543 4.160194174757281 -0.3630916654832039 0.5588259704139191 1.187823508180765 0.7163607874738429 0.7705383934241111 0.2959477455150902 1.0 1.0 1.0 0.1988473022417859 0.0675218785318175 +Protein lipid complex 2 5 1.972343226773393 0.0485704381458833 0.9733009708737864 4.152912621359223 0.8806614337674874 0.2932450111231078 0.8822773800999041 1.1227636940840768 1.0732388951245535 0.2459144485958364 1.0 1.0 1.0 0.3258327648280404 0.1807018090276839 +Dendritic shaft 2 6 1.9687221543435327 0.0489850058052183 1.2402912621359223 5.310679611650485 0.894315195377243 0.3713817419556685 0.9794132940711298 1.209020515164722 0.8832746734598869 0.2869302240585097 0.1374990224216387 0.0892490045576324 0.1677870330809631 0.0768284795296569 0.0618109910728358 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e152a33492df152d0c58458569fd1755bbf07dbf --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 912, + "title": "Average number of proteins per term", + "value": 30.44078947368421 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e14ffbef7040683080ff8f95cf768924feb8e57a --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3cfc562b8f96121af020323bd003c41aa2e12a7c --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,314 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Vacuole 0.6843583628944283 6.697446727323501 2.1209250786016012e-11 1.9342837441979043e-08 1.9342837628846605e-08 234 P07858,Q99523,P07602,P34059,Q9UIQ6,P17900,O75503,P98164,P42892,O14773,O00584,Q9UMR5,O75629,Q07954,Q01459,P04066,Q8NHP8,P06280,Q99538,P06865,Q14108,P11117,Q9BTY2,P54802,P50897,P15586,P53634,Q9HAT2,P10253,Q8TCT8,Q8IV08,Q92820,P10619,P51790,P13473,P11279,Q13510,P07686,P61916,O43567,P27105,P42785,Q8NCC3,O00462,Q99519,Q9NQ11,Q9UM22,O00754,Q96GC9,Q5BJF2,P17655,Q92542,P08195,O15118,P04062,P16278,P38571,P08236,Q8N1F8,Q8TBX8,Q8WTV0,Q93050,P04114,Q9NV96,Q96BM9,P15291,O15260,O15400,Q9NUM4,O00560,Q9UN37,Q13277,Q99536,P07384,P51797,P20645,O60784,P61421,Q9Y487,O95772,P61160,Q9UHG3,O75955,P51798 84 +Golgi apparatus 0.5738290835176704 5.985373656914157 2.158936526275958e-09 1.968948176620088e-06 9.844750564378373e-07 348 Q6P4E1,Q99523,P05067,Q15392,O75503,P98164,O14773,Q9Y287,P11717,Q92859,Q07954,Q8IZA0,P06280,O43493,Q14108,Q8NBN3,P19021,P50897,Q92896,P53634,Q8NCH0,Q9NPR9,Q7LGA3,Q8IV08,P51790,Q8NBZ7,Q9NX62,O43567,O43505,Q5VW38,Q11206,Q8WVQ1,P35670,Q93063,O43852,Q9UQB8,P17655,Q9BRK5,P80303,Q92542,P10321,Q8TD16,O15118,P04062,P16278,Q13190,Q9NRB3,Q92520,Q6ZRP7,O43752,Q99805,Q9Y6B6,O00461,O60512,Q86SF2,Q92544,Q10472,P01889,Q93050,Q9NV96,O43731,Q9P2E5,P15291,Q8NDZ4,O15260,P04439,Q16739,Q10471,Q92572,O60645,Q9UQ16,Q04656,Q16706,Q9UNK9,O43909,P20645,P84085,Q9Y282,Q86Y82,Q8TAD4,P46934,Q4J6C6,O15126,Q9UJU6,Q8NEY8,Q02818,Q9UQR1,Q969X5,O15027 89 +Secretory vesicle 0.5834446498323689 5.750323553927877 8.907282035103375e-09 8.123408258045617e-06 2.239623940530852e-06 284 Q08722,P10321,P07858,O60645,Q13277,P07602,P34059,P17900,P05067,Q04656,P16278,P42892,Q06481,Q92520,O00584,Q13576,O43752,Q08431,P11717,Q99536,O75629,Q9HBM0,P07384,P04066,Q16539,P06280,P06865,Q8N1F8,P08236,Q9BTY2,P68402,P01889,P19021,P50897,P15586,Q08380,P78310,P53634,Q9UNP9,P10253,Q93050,O60784,Q92820,P10619,P51790,P13473,P11279,Q9NV96,Q96BM9,Q7L0J3,P61421,Q9Y487,P07686,Q13510,P15291,P61916,Q86Y82,Q8TAD4,P27105,O15260,P42785,O15400,O00462,Q99519,Q8WVQ1,O00754,O00560,Q9UQB8,Q92542 69 +Secretory granule 0.5944560250318708 5.733758584820721 9.82291201887216e-09 8.95845567891894e-06 2.239623940530852e-06 257 Q08722,P10321,P07858,O60645,Q13277,P07602,P34059,P17900,P05067,Q04656,P16278,P42892,Q06481,Q92520,O00584,Q13576,Q08431,P11717,Q99536,O75629,Q9HBM0,P07384,P04066,Q16539,P06280,P06865,Q8N1F8,P08236,Q9BTY2,P68402,P01889,P19021,P15586,Q08380,P78310,P53634,Q9UNP9,P10253,Q93050,O60784,Q92820,P10619,P51790,P13473,P11279,Q9NV96,Q96BM9,Q9Y487,Q13510,P07686,P15291,P61916,Q8TAD4,P27105,O15260,P42785,O15400,P61160,O00462,Q99519,Q8WVQ1,O00754,O00560,Q9UQB8,Q92542 65 +Endosome 0.5816620781637603 5.411064932580003 6.265104784151656e-08 5.713612509167307e-05 1.142755112647502e-05 239 O15126,P10321,P07858,Q99523,P05556,P07602,Q9UIQ6,O15118,Q04656,P05067,Q9UJU6,Q9UH99,P98164,P42892,Q06481,O14773,Q9H223,Q9Y287,O43752,P11717,Q99805,P02786,Q07954,O00461,Q99538,O43493,Q14108,Q92544,P51797,P01889,P20645,Q15904,Q93050,Q9Y6I3,O60784,Q8TCT8,P04083,Q8IV08,P04114,P31751,P51790,P13473,P11279,Q9NV96,Q96BM9,P61421,Q13510,Q9Y487,O95772,P23258,Q86Y82,O43567,Q9NWW5,O15400,Q5VW38,P04439,Q9UN37,Q9NQ11,Q9UBB6,Q9H4M9,P35670,P10644,O75955,Q9NUM4,Q9BRG1,Q9BRK5,Q92542 67 +Vesicle membrane 0.5476021915081796 5.1687338958474305 2.3568519433636994e-07 0.0002149218235605 3.582414953928023e-05 275 Q99523,P07602,Q9UIQ6,P98164,P42892,Q06481,Q9Y287,Q08431,P11717,P02786,Q07954,Q5KU26,O43493,Q14108,P19021,Q15904,P10253,Q8TCT8,Q8IV08,P51790,P13473,P11279,Q7L0J3,O43567,P27105,P42785,O00462,Q9NQ11,Q9BRG1,Q92542,Q08722,P10321,O15118,Q13190,O43752,Q99805,Q9Y6B6,O00461,Q8WTV0,P01889,Q93050,P04083,P04114,Q9NV96,O43731,Q96BM9,P15291,Q8NDZ4,O15260,O15400,P04439,Q9NUM4,Q9UN37,Q92572,O60645,Q13277,Q9NVZ3,Q04656,Q9H223,Q13576,P51797,P20645,Q9Y6I3,O60784,P61421,Q9Y487,O95772,Q86Y82,Q8TAD4,Q9UBB6,Q9H4M9,P06756,O15126,P05556,Q14728,Q9UJU6,Q9UH99,O75787,O15027,Q9Y3E7,Q92783 81 +Vacuolar membrane 0.6202995906991259 4.77006673855673 1.8416489275807637e-06 0.0016781756544087 0.0002399405459935 134 Q99523,P07602,P08195,Q9UIQ6,O15118,P04062,O75503,P98164,P42892,Q07954,Q14108,P11117,Q8N1F8,Q8WTV0,P51797,P20645,P10253,Q93050,O60784,Q8TCT8,Q8IV08,P10619,P51790,P13473,P11279,Q9NV96,Q96BM9,P61421,Q9Y487,O95772,P15291,O43567,P27105,O15260,P42785,O15400,O00462,Q99519,Q9NQ11,O75955,P51798,Q96GC9,Q9NUM4,Q9UN37,Q92542 45 +Early endosome 0.6269065655678555 4.674997025640154 2.9395787990438293e-06 0.0026773094024264 0.0003343184802489 110 P10321,Q99523,Q9UIQ6,Q04656,P05067,Q9UJU6,Q06481,Q9H223,O43752,P11717,P02786,Q07954,Q92544,Q92783,P01889,O60784,P04083,Q8IV08,P04114,P31751,P51790,Q9NV96,P61421,Q13510,Q86Y82,Q9NWW5,O15400,Q5VW38,P04439,Q9H4M9,O75955,Q9UN37,Q92542 33 +Vesicle lumen 0.6102778644549269 4.651255947416265 3.299195528772003e-06 0.00300434916909 0.0003343184802489 133 P34059,P17900,P05067,P16278,Q92520,O00584,Q99536,O75629,P04066,Q16539,P06280,P08236,Q8N1F8,Q9BTY2,P68402,P15586,Q08380,P53634,Q92820,P10619,P04114,P07686,P61916,Q99519,Q8WVQ1,O00754,O00560 27 +Golgi membrane 0.5796725132920175 4.4264184230269095 9.581059208452205e-06 0.0086999027677246 0.0008737925998109 146 P10321,Q15392,Q13190,Q9NRB3,Q6ZRP7,Q9Y287,O43752,P11717,Q8IZA0,O00461,O60512,Q86SF2,Q14108,Q8NBN3,Q10472,P01889,Q92896,Q8NCH0,Q7LGA3,Q8IV08,P51790,O43731,Q9P2E5,P15291,O43567,Q8NDZ4,O15260,O43505,Q11206,P04439,Q16739,P35670,Q93063,Q10471 34 +Endosome membrane 0.5569687364073584 4.101007333020056 4.1135552275139986e-05 0.0368213740198659 0.0034105112431753 139 O15126,P10321,P05556,Q99523,O15118,Q04656,Q9UH99,P42892,Q06481,Q9H223,O75787,Q9Y287,P11717,Q99805,P02786,O00461,Q9Y3E7,Q14108,Q92783,P51797,P01889,Q15904,Q93050,Q8TCT8,P04083,Q8IV08,P04114,P61421,P51790,P13473,P11279,Q9NV96,Q96BM9,Q9Y487,O95772,Q86Y82,O43567,O15400,P04439,Q9NQ11,Q9UBB6,Q9H4M9,Q9NUM4,Q9BRG1,Q9UN37,Q92542 46 +Perinuclear region of cytoplasm 0.5069851992686454 3.970451813031655 7.173646432212522e-05 0.0633316444116762 0.0050325888816753 192 O60645,P07858,Q99523,P05556,Q9UQ16,Q9UIQ6,O15118,Q04656,P05067,Q8TAG9,P16278,O75503,Q5SQN1,P42892,Q9H223,Q9H2J4,Q9UNK9,O43752,Q9UNS2,P11717,P02786,Q99538,Q10472,P19021,P20645,P84085,Q93050,P11279,Q9Y487,A0MZ66,P27105,O15400,P58546,Q01105,P35670,Q9H4M9,P46934,Q15056,P31946,Q10471,P17655,Q9UN37,O95831 43 +Golgi apparatus subcompartment 0.5714319620841956 3.815040487018337 0.0001361606074623 0.1167852728899959 0.0088698910004048 103 Q99523,P04062,P05067,Q04656,Q16706,O43752,P11717,Q9Y6B6,O00461,O60512,O43493,Q8NBN3,Q10472,P19021,Q9NPR9,Q8NBZ7,Q9P2E5,Q9NX62,P15291,Q11206,P04439,Q8WVQ1,P35670,Q10471 24 +Transport vesicle 0.5920762789447795 3.781680560848731 0.0001557731734009 0.1324448539599604 0.0090865386548311 101 P10321,Q13277,Q99523,Q04656,P05067,Q13190,O43752,P11717,Q9Y6B6,O00461,O43493,P01889,P19021,P50897,P20645,P61421,P51790,Q9NV96,P11279,O43731,Q7L0J3,O15260,O15400,P04439,Q9NQ11,Q92572,Q92542 27 +Vacuolar lumen 0.8748828045135757 3.746712970263623 0.0001791668962149 0.1507611905864883 0.0096117770204753 73 P07858,P07602,P34059,P17900,P04062,P16278,O14773,O00584,Q9UMR5,P38571,O75629,P04066,Q8NHP8,P06280,Q99538,P06865,P08236,P11117,Q14108,Q8N1F8,Q9BTY2,P54802,P50897,P15586,P53634,P10253,Q8IV08,Q92820,P10619,P13473,Q13510,P07686,P61916,O00462,Q99519,Q9NQ11,Q9UM22,O00754 38 +Plasma membrane region 0.4796774675937495 3.650680410002095 0.0002615465198139 0.2122398588879003 0.0132516903372384 200 Q15375,O60645,P07858,Q99523,Q13277,P08195,Q9UQ16,P05556,P30825,Q9NVZ3,Q04656,P05067,Q14728,Q9UJU6,P98164,Q06481,O75787,P08069,Q9HBM0,P02786,Q07954,Q9NQX3,Q8WTV0,P78310,Q9Y6I3,P04083,Q9BY67,P31751,P51790,Q9NV96,P61421,P40855,P15291,Q8TAD4,Q14168,Q16181,Q99720,Q9H4M9,P35670,P06756,P09493,P10644,P46934,P19022,O75955,Q13572,Q9UQB8,Q92542 48 +Endocytic vesicle 0.6587858242256861 3.5721682094501706 0.0003540378816735 0.275982501657308 0.01699381832033 93 P10321,Q04656,P98164,Q06481,Q9H223,O43752,P11717,P02786,Q07954,Q5KU26,O00461,O43493,Q14108,Q8WTV0,P01889,P20645,Q93050,P04114,P61421,P51790,P13473,P11279,Q9Y487,Q86Y82,O15400,P04439,Q9H4M9 27 +Cell surface 0.7127267484609405 3.5156978386022777 0.0004385998456903 0.3297408199930985 0.0200001529634818 87 Q9H813,Q08722,P10321,P07858,Q99523,P05556,P08195,P05067,Q13641,P98164,P42892,O75787,P08183,Q13576,Q08431,P11717,Q92859,P02786,Q8WTV0,P01889,P19021,Q14126,P36896,Q07021,P04083,P23229,P51790,P11279,P43121,P15291,Q13685,P04439,P06756,P19022,O75955,P17655 36 +Azurophil granule 0.8050878137351655 3.4588328810763587 0.0005425214113814 0.3903765393220053 0.0235609298657085 76 Q13277,P07602,P34059,P17900,P16278,O00584,O75629,P04066,P06280,P06865,P08236,Q8N1F8,Q9BTY2,P15586,P53634,P10253,Q92820,P10619,Q9NV96,P11279,P13473,Q96BM9,P07686,P15291,P61916,P27105,O15260,P42785,O15400,O00462,O00754,O00560,Q92542 33 +Coated vesicle 0.6105930454898125 3.422022667367389 0.0006215713143289 0.4328033940872177 0.0257669563030906 96 O15126,P10321,Q99523,Q9NVZ3,Q04656,P05067,Q9UJU6,Q13190,P98164,P42892,O43752,P11717,Q969X5,P02786,O15027,Q9Y6B6,O43493,Q14108,P01889,P20645,P53634,Q9Y6I3,P04114,Q9Y282,O43731,Q8NDZ4,Q5VW38,P04439 28 +Endoplasmic reticulum 0.3872540425007829 3.272768241519762 0.0010649976351524 0.6215969626714715 0.0422294714460447 516 Q6UXD5,Q99523,P05067,Q13641,Q15392,O75503,P98164,Q06481,O00584,Q08431,O43493,Q14108,Q9BTY2,P53634,Q15904,Q8TCT8,Q8IV08,P10619,Q7L0J3,Q13510,P61916,O43567,Q9NWW5,P27105,Q99720,P48449,Q6P179,Q8WVQ1,Q93063,Q9P0I2,O43852,Q96GC9,Q5BJF2,Q9UQB8,P17655,Q9BRK5,P80303,P48723,Q92542,P10321,O15118,P04062,Q13190,Q14257,Q9H173,Q9Y6B6,Q8TBX8,Q10472,P01889,Q9UBM7,P04114,Q9NV96,O43731,O15260,P60604,P04439,Q01105,Q15041,Q96N66,O14657,O00560,Q10471,Q04656,O15460,Q9H223,Q9H2J4,Q9UNK9,Q9NZ08,P63220,P62857,O43909,Q9BU23,Q9Y680,Q9Y282,P62942,O95772,Q5JRA6,Q15125,Q6NUK4,Q96G23,P19022,P51648,O75787,Q02818,Q969X5,O15027,P13674,Q12907,Q9H490,O43464,Q8NB49,Q15631,Q8IXB1,O43292,Q13555,Q32P28,P06493,O00264,Q9Y2B0,Q9UNN5,Q9GZZ9,Q8IY95,O95486,O75915,O75844 105 +Somatodendritic compartment 0.4783821876737678 3.230166479965437 0.0012371815549434 0.6766461731699178 0.0470128990878513 154 Q15375,P05556,Q13277,O95816,P08195,Q9UQ16,O60313,Q7L576,P05067,Q13641,Q04656,P98179,P98164,Q9UJU6,O75787,P23634,P08069,P10586,P21359,Q9Y5K6,Q9NQX3,P61586,Q14444,P19021,P50897,P04114,Q7L0J3,A0MZ66,O60333,O00264,Q14168,Q14203,Q9NQ11,Q9UBB6,P46934,Q9UQB8,P17655 37 +Intrinsic component of plasma membrane 0.6180359691345033 3.1253847891854627 0.0017757261316853 0.8022796849706413 0.06477848928388 92 Q9H813,Q08722,Q15375,P10321,Q9H1Z9,P05556,O15111,P30825,Q9UIQ6,O60637,O15118,P05067,Q13641,P08069,P11717,Q92859,Q99805,P02786,Q07954,Q9H2J7,P10586,Q12907,Q9NQX3,Q8WTV0,O43464,P01889,P20645,P78310,Q8NB49,P36896,P23229,P51790,P11279,O00264,Q8TAD4,P27105,Q7L5Y9,P04439,P35670,P06756,P19022,O00560,Q92542 43 +Neuron projection 0.4250529514986293 3.0450514511899196 0.0023264050773861 0.8804658542724676 0.0816031319452365 236 Q15375,O60645,Q13277,P05556,O95816,Q9UQ16,O60313,Q8TAG9,Q7L576,P05067,Q13641,Q04656,P98179,P98164,Q96N67,Q9UJU6,O75787,P23634,O15511,P08069,Q92859,Q9HBM0,P10586,P21359,Q9Y5K6,Q9NQX3,P61586,Q14444,P19021,P50897,P78310,Q15555,Q9BY67,Q13555,P61421,P51790,Q96BM9,Q7L0J3,A0MZ66,O60333,O00264,Q14168,Q99720,Q14203,Q9Y496,P58546,Q9NQ11,Q9UBB6,P46934,P19022,Q9UQB8,P17655,P29992,Q92572 54 +Lysosomal lumen 0.9380249338039032 3.008143137150979 0.0026284930486015 0.9093130383660636 0.0869839025580089 42 P07858,P07602,P34059,P17900,P04062,P16278,O14773,O00584,Q9UMR5,P38571,P04066,Q8NHP8,P06280,Q99538,P06865,P08236,P11117,Q14108,P54802,P50897,P15586,P10253,Q8IV08,P10619,P13473,Q13510,P07686,P61916,O00462,Q99519,Q9NQ11,Q9UM22,O00754 33 +Dendritic tree 0.4748945723427422 3.0033150198758927 0.0026705584118686 0.9127351220535402 0.0869839025580089 118 Q15375,P05556,Q13277,O95816,Q9UQ16,O60313,Q7L576,P05067,Q13641,Q04656,P98179,P98164,Q9UJU6,O75787,P23634,P21359,Q9Y5K6,Q9NQX3,P61586,Q14444,P50897,Q7L0J3,O60333,Q14168,Q9UBB6,P46934,Q9UQB8,P17655 28 +Endolysosome lumen 0.9884921805842418 2.9263460971466655 0.0034296915366061 0.956424264410752 0.0921878153481537 2 P07858 1 +Autolysosome 0.979049867217468 2.887991751559385 0.003877100394259 0.9710674458959194 0.0930504094622169 2 P13473 1 +Secondary lysosome 0.979049867217468 2.887991751559385 0.003877100394259 0.9710674458959194 0.0930504094622169 2 P13473 1 +Axon 0.4562149323915745 2.8133575241230213 0.0049027107077641 0.9886922709389728 0.1011040839681522 132 O60645,Q13277,O95816,Q15334,Q9UQ16,O60313,Q8TAG9,Q7L576,P05067,Q13641,Q04656,Q96N67,P98164,O75787,O15511,P08069,P46060,Q92859,P21359,Q9Y5K6,P61586,P50897,P78310,P61421,P51790,Q96BM9,A0MZ66,O60333,Q14168,Q13136,Q99720,Q14203,Q8N3R9,Q9Y496,P58546,Q9UBB6,P43034,Q9UBF2,Q9UL25,Q92572 40 +Integral component of lysosomal membrane 0.959575095898494 2.8083214686417306 0.0049800486759439 0.989466043460436 0.1011040839681522 2 Q9NQ11 1 +Intrinsic component of vacuolar membrane 0.9598583234946856 2.8062128991423743 0.0050127560459616 0.9897771533090728 0.1011040839681522 3 Q9NQ11,P13473 2 +Platelet dense granule lumen 0.9566243729713746 2.7961833944322754 0.0051710048199515 0.9911575537004224 0.1011040839681522 2 Q08380 1 +Golgi lumen 0.9455243473262024 2.741060104010538 0.0061241303763277 0.9963109242164788 0.1048875046587414 5 Q9BRK5,P05067,Q9NX62 3 +Endosome lumen 0.9405282828559132 2.7165451925387547 0.0065967188407771 0.9976092278748558 0.1083727301326705 7 P07858,Q99538,Q9UIQ6,P05067,P98164 5 +Cell leading edge 0.4513673155969332 2.713348031571348 0.0066607111114258 0.997745640294614 0.1083727301326705 119 Q96AC1,P05556,Q13277,Q10713,Q7L576,P05067,Q04656,Q9UJU6,Q06481,O75787,P23634,O15511,Q13576,Q9HBM0,P15311,Q9Y5K6,P61586,Q14444,P31751,P51790,A0MZ66,P23258,Q14168,Q9P2B4,P61160,P41440,P06756,P09493,P19022,O75955,P31749,Q9UHY1,Q9UQB8 33 +Mhc class i protein complex 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9981771954913196 0.1083727301326705 3 P10321,P01889 2 +Mhc protein complex 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.9981771954913196 0.1083727301326705 3 P10321,P01889 2 +Nuclear envelope lumen 0.9277073202642234 2.666025155507738 0.0076753949520189 0.9991123758701946 0.1111340898640466 5 P05067 1 +Secretory granule membrane 0.6525093586795796 2.6377090135203547 0.0083468170223874 0.9995212079772842 0.111360899644917 81 Q08722,O15126,P10321,O60645,Q13277,P07602,Q06481,Q13576,Q08431,P11717,P01889,P19021,P10253,Q93050,O60784,P13473,P11279,Q9NV96,Q96BM9,P15291,Q8TAD4,P27105,O15260,P42785,O00462,P06756,Q92542 27 +Cell body 0.4446971176333903 2.6256782759532773 0.008647651071822 0.9996369449879128 0.111360899644917 109 Q15375,P08195,Q7L576,P05067,Q04656,Q9UJU6,O75787,P08069,P10586,P19021,P50897,P78310,P04114,Q7L0J3,A0MZ66,O00264,Q14168,Q14203,Q9NQ11,Q9UBB6,Q9UQB8,P17655 22 +Ficolin 1 rich granule 0.5459091035537623 2.62368588275165 0.008698396596056 0.999653504595958 0.111360899644917 94 P07858,Q8WVQ1,Q16539,P13473,P11279,P08236,Q96BM9,Q13510,Q9UJU6,P16278,P68402,P15586,P61160,P42785,Q9UNP9,P10253,P07384,Q93050 18 +Side of membrane 0.6122156710508939 2.5564261257971097 0.0105753523664229 0.9999384759219484 0.1303340724078069 85 Q96AC1,P10321,P07858,P05556,O15111,P17900,P98164,P42892,Q9UBI6,O75787,P08183,Q08431,P02786,P15311,P62857,O43464,P61586,P01889,P11413,Q8TCT8,P04083,P23229,P10619,P51790,P11279,P62942,P43121,P15291,P04439,P41440,P06756,O75955,P31749,P17655,P29992 35 +Intrinsic component of organelle membrane 0.430930135022137 2.5171869220130194 0.0118296051122552 0.999980651972055 0.130493410401354 140 O15126,P10321,O15118,Q9UH99,Q9NRB3,P42892,Q6ZRP7,Q9Y287,O43752,Q969X5,O60830,Q9H490,P01889,Q15070,Q99595,Q9UBM7,Q8TCT8,O43292,P13473,Q9Y282,Q7L0J3,Q9H3K2,Q6P4A7,Q86Y82,O43505,Q15125,P04439,Q9NQ11,Q9NWR8,Q15041,Q9P0I2,Q10471,Q9BWH2 33 +Protein complex involved in cell adhesion 0.8866587957497039 2.4985408524139854 0.0124705768008797 0.9999892936779964 0.130493410401354 3 P06756,P23229 2 +Integrin complex 0.8866587957497039 2.4985408524139854 0.0124705768008797 0.9999892936779964 0.130493410401354 3 P06756,P23229 2 +Chloride channel complex 0.8861717201874215 2.4885150365193898 0.0128277812590531 0.9999923025398914 0.130493410401354 5 Q9H813 1 +Vacuolar proton transporting v type atpase v0 domain 0.881901387658696 2.473932529816604 0.0133634931619524 0.9999953080976162 0.1310484490720493 4 Q9Y487,P61421,Q93050 3 +Proton transporting v type atpase v0 domain 0.881901387658696 2.473932529816604 0.0133634931619524 0.9999953080976162 0.1310484490720493 4 Q9Y487,P61421,Q93050 3 +Phospholipid translocating atpase complex 0.8710534080849719 2.436369605620977 0.0148355171476171 0.999998797800358 0.1409374129023625 2 Q9NV96 1 +Golgi medial cisterna 0.8695354568614183 2.424950318536273 0.015310481827514 0.9999992255823414 0.1418389515525553 3 P04439 1 +Azurophil granule lumen 0.8082404190671368 2.3837032738256982 0.0171394158390194 0.999999857888256 0.1496743101849813 45 P04066,Q92820,P10619,P34059,P06280,P08236,P17900,Q8N1F8,O00754,P16278,Q9BTY2,P07686,P61916,O00560,O00584,P15586,P53634,O75629 18 +Dopaminergic synapse 0.85836529949838 2.381714755661811 0.017232239659455 0.9999998696167696 0.1496743101849813 2 O75955 1 +Triglyceride rich plasma lipoprotein particle 0.8489105678429538 2.3354891806295557 0.0195178804563136 0.999999984404962 0.1618209725105276 3 P04114 1 +Cornified envelope 0.8491957736630257 2.3233738872541827 0.0201590756535536 0.9999999914121622 0.163767806132087 6 Q14126,Q14574 2 +Presynaptic cytosol 0.8430180093030625 2.309765018796066 0.0209011669511376 0.9999999956967354 0.1659660515722926 3 Q9UQB8 1 +Platelet dense granule 0.8410992046754753 2.2963890852509103 0.0216536444895563 0.9999999978655796 0.1690737684440599 4 Q08380,P13473 2 +Integral component of synaptic vesicle membrane 0.841778563830763 2.2947485901569293 0.0217475364105064 0.9999999980444602 0.1690737684440599 5 O43752,Q86Y82,Q7L0J3 3 +Presynapse 0.4792103737523656 2.292517955071907 0.0218757726714902 0.9999999982648272 0.1690737684440599 98 O15126,O60645,Q13277,Q9UQ16,Q7L576,P05067,Q13641,Q5SQN1,O43752,P21359,P50897,Q07021,P61421,P51790,P11279,Q7L0J3,P56545,O60333,Q86Y82,O15400,P41440,P19022,O75955,Q9BT78,Q9UQB8,Q92542 26 +Organelle subcompartment 0.3554697544940249 2.281632163179571 0.0225110661704064 0.9999999990405846 0.1725217844320224 410 Q6UXD5,Q99523,P05067,Q15392,P11717,O43493,Q14108,Q8NBN3,P19021,Q15904,Q9NPR9,Q8TCT8,Q8IV08,Q8NBZ7,Q9NX62,O43567,Q9NWW5,Q11206,Q99720,P48449,Q6P179,Q8WVQ1,P35670,Q93063,Q9P0I2,O43852,Q96GC9,Q5BJF2,P10321,P04062,Q13190,O43752,Q9Y6B6,O00461,O60512,Q10472,P01889,Q9UBM7,P04114,O43731,Q9P2E5,P15291,O15260,P04439,Q15041,Q96N66,O00560,Q10471,Q04656,Q16706,Q9NZ08,P62857,O43909,Q9BU23,P20645,Q9Y282,P62942,O95772,Q5JRA6,Q15125,Q6NUK4,Q96G23,Q4J6C6,O15126,P51648,O75787,Q969X5,O15027,Q12907,Q9H490,O43464,Q8NB49,O43292,Q13555,P06493,O00264,Q9UNN5,O14828,Q9GZZ9,O95486,O75915 81 +Desmosome 0.8350646084655893 2.257565816221852 0.0239727418530233 0.999999999754927 0.1792060702455515 7 Q14126,Q14574 2 +Clathrin coated endocytic vesicle membrane 0.8349402599220102 2.248972942305411 0.0245142175950592 0.9999999998522592 0.1817639548511708 16 P04114,O43493,Q14108,P98164,P11717,P02786 6 +Azurophil granule membrane 0.825237798294213 2.2340810674438374 0.0254777394870397 0.9999999999400088 0.1858855872974423 25 O00462,P07602,Q9NV96,P11279,P13473,Q96BM9,P15291,P27105,P42785,P10253,Q92542 11 +Anchored component of synaptic membrane 0.8096783712009321 2.1688521430553496 0.0300939110433431 0.9999999999992104 0.1988814990690502 2 Q9NQX3 1 +Endolysosome 0.8145126997584586 2.1572335449859894 0.0309874719881688 0.9999999999996592 0.2033134852748921 10 P07858 1 +Endocytic vesicle membrane 0.7560698653659776 2.147506269874048 0.0317529985749198 0.9999999999998342 0.203630942706696 48 P10321,Q04656,P98164,Q06481,P11717,P02786,Q07954,Q5KU26,O43493,Q14108,Q8WTV0,P01889,P20645,Q93050,P04114,P61421,P13473,P11279,P04439 19 +U2af complex 0.8037190082644567 2.136338831755733 0.0326518059051148 0.999999999999929 0.203630942706696 3 Q01081,P26368 2 +Proteasome core complex beta subunit complex 0.8076241134751982 2.1342527995170304 0.0328220927389082 0.9999999999999396 0.203630942706696 7 P28070,P49721,P49720,P20618,P28074,P28072 6 +Transcription preinitiation complex 0.797104116268885 2.106831247639074 0.03513220986496 0.9999999999999932 0.2094155254695656 3 Q00403 1 +Cell cell junction 0.4016888037151735 2.0704772850145616 0.038407671044262 0.9999999999999996 0.2231069808431016 117 Q96AC1,Q9NR77,Q13277,Q69YQ0,P05556,Q14254,P05067,O00192,Q9Y624,Q9HBM0,Q14574,P15311,Q13308,Q9Y5K6,Q9UNF0,P61586,P16989,P12814,P05026,P78310,Q14126,P04083,Q9BY67,P60953,Q7L0J3,Q68EM7,P15291,P15924,Q14168,Q8N3R9,P41440,Q9UDY2,Q00013,P19022,O75955,P31749,Q04917,P14923,O00560,Q9UQB8 40 +Clathrin coated endocytic vesicle 0.7931894046306526 2.0607603921566815 0.0393259048856895 1.0 0.2269950965553725 21 P04114,O43493,Q14108,P98164,P11717,P02786 6 +External side of plasma membrane 0.7859966426870584 2.057581551948101 0.0396303190511264 1.0 0.2273135281423103 28 P04083,P05556,P07858,P23229,P51790,P11279,P06756,O75955,P98164,P42892,P15291,O75787,P43121,P17655,Q08431,P02786 16 +Anchoring junction 0.3614562247396282 2.0276484880682744 0.04259613649832 1.0 0.2398004721386907 258 Q96AC1,Q9NR77,Q13277,Q69YQ0,Q10713,P05556,Q14254,P63104,Q7L576,P05067,P23396,Q96N67,O15511,O00192,P11717,Q9Y624,P07384,Q9HBM0,Q07954,P42356,P46783,Q14574,P15311,Q13308,Q9Y5K6,Q14108,Q9UNF0,P67936,P61586,P16989,P12814,Q9UBG0,P78310,Q14126,Q15555,P04083,Q9BY67,P23229,P62258,Q7L0J3,P43121,Q68EM7,P15291,Q16527,Q14168,Q13136,P61160,Q8N3R9,P41440,Q9UDY2,P06756,P19022,O75955,P31749,P11233,Q04917,P31946,O00560,Q9UQB8,P17655,Q9UL25,Q92542 62 +Dendritic spine membrane 0.7712514757969227 1.9906528475849097 0.0465190659441199 1.0 0.2555746273556468 3 O75787,P23634 2 +Dendrite membrane 0.7714791851195901 1.9853824330776044 0.047101938923014 1.0 0.2567489959445928 4 O75787,Q14168,P23634 3 +Glial cell projection 0.7719077684393236 1.981371267983436 0.0475496534325612 1.0 0.2567489959445928 5 P05067 1 +Unconventional myosin complex 0.7703514820204431 1.9742772934231485 0.0483502213394992 1.0 0.2567489959445928 5 P14649 1 +Protein lipid complex 0.7699273664994362 1.9723432267733931 0.0485704381458833 1.0 0.2567489959445928 5 Q9UHG3,P04114 2 +Chitosome 0.765122455001456 1.969755202864148 0.0488664329329673 1.0 0.2567489959445928 2 Q04656 1 +Dendritic shaft 0.7703525085677112 1.9687221543435327 0.0489850058052183 1.0 0.2567489959445928 6 P05067,Q9UQB8 2 +Axonal growth cone 0.7694016744533727 1.9558145715421116 0.0504870017051417 1.0 0.2616144633811891 8 Q92859,A0MZ66 2 +Cd40 receptor complex 0.7615895649658865 1.9468903597362448 0.0515478806446303 1.0 0.2648797503165002 3 O15111 1 +Centriolar subdistal appendage 0.7566980976922797 1.92466546443916 0.054271223710731 1.0 0.2734550056584899 3 Q5SW79 1 +Intrinsic component of postsynaptic specialization membrane 0.7582447165348614 1.9189284873869987 0.0549933848056576 1.0 0.2740819348111911 5 Q15375,P19022,P23634 3 +Hippocampal mossy fiber to ca3 synapse 0.7555079867210903 1.912647874731616 0.055793146395112 1.0 0.2750451324991468 4 Q15375 1 +Microvillus membrane 0.7524817785260626 1.898810417122437 0.0575894070491307 1.0 0.2800004796697047 4 P06756 1 +Pigment granule 0.6524424049923891 1.8978230395076996 0.0577193971248952 1.0 0.2800004796697047 64 P07858,Q13277,Q92820,P08195,P62258,P11279,Q04656,O75955,O43852,P31946,O14773,O00560,P27105,P55209,Q93050,Q92542,P02786 17 +Endoplasmic reticulum lumen 0.6218135274778066 1.8862116461736091 0.0592664397530202 1.0 0.2813186050137299 70 P05067,O15460,Q14257,Q06481,Q02818,Q9H173,O00584,Q9NZ08,Q08431,P13674,O43493,Q9Y680,Q9BTY2,P53634,Q8IXB1,P04114,Q9NWW5,Q5JRA6,Q6P179,P19022,O43852,O14657 22 +Golgi cisterna membrane 0.7558529806160836 1.885943039287489 0.0593026308701116 1.0 0.2813186050137299 24 Q9Y6B6,Q99523,O00461,O60512,Q8WVQ1,Q8NBZ7,Q9P2E5,P15291,Q8NBN3,Q10472,Q11206 11 +Brush border membrane 0.7546425135214329 1.879985126914766 0.0601101049608723 1.0 0.2813186050137299 10 Q14728,Q04656,P40855,P98164,P15291 5 +Intrinsic component of postsynaptic density membrane 0.7436356881319273 1.8582615991700584 0.0631318742146542 1.0 0.2907787786303012 4 Q15375,P23634 2 +Apicolateral plasma membrane 0.7300436996091573 1.7825737821228422 0.0746557108147367 1.0 0.323185398081546 6 P46934,P78310 2 +Anchored component of plasma membrane 0.7255017709563023 1.7818600281438262 0.0747720603017612 1.0 0.323185398081546 3 Q9NQX3,Q15334 2 +Postsynaptic recycling endosome 0.7237082024306699 1.7735959295480517 0.0761300114754546 1.0 0.3259651195568761 3 Q86Y82 1 +Clathrin coated pit 0.728226778985377 1.757262351317178 0.0788731018391888 1.0 0.3333715903099444 27 P98164,Q99523,P05067,P02786 4 +Cell trailing edge 0.7245075629138414 1.7567734673074964 0.0789564292839342 1.0 0.3333715903099444 6 Q14254,P41440,P15311,O75955 4 +Clathrin coated vesicle membrane 0.7241519309661 1.7458262513610243 0.0808411479154995 1.0 0.3366535474837242 29 Q9Y6I3,P04114,O43493,Q9NVZ3,Q14108,P98164,P20645,P11717,P02786 9 +Phagophore assembly site 0.7183068225380584 1.7278127408280588 0.0840218024095655 1.0 0.3467325058711484 6 Q96GC9 1 +Cell body membrane 0.7111708756057755 1.7156739570466468 0.0862217339147588 1.0 0.3489376015939546 3 P23634 1 +Intrinsic component of presynaptic membrane 0.71416969868128 1.7084539565207812 0.0875521428585899 1.0 0.3517513404715154 6 P19022,Q92542,P23634 3 +Golgi cisterna 0.7136245890547913 1.7019902202393504 0.0887572015899313 1.0 0.3519415993479018 31 Q9Y6B6,Q99523,O00461,O60512,Q8WVQ1,Q8NBZ7,Q9P2E5,P15291,Q8NBN3,Q10472,Q10471,Q11206,P04439 13 +Intrinsic component of synaptic vesicle membrane 0.7129861551720736 1.6873228697280267 0.0915412858094018 1.0 0.3568019979169062 9 O43752,Q86Y82,Q7L0J3 3 +Atpase dependent transmembrane transport complex 0.7046095612082809 1.6852564126603606 0.0919391113053431 1.0 0.3568019979169062 3 P54709 1 +Cation transporting atpase complex 0.7046095612082809 1.6852564126603606 0.0919391113053431 1.0 0.3568019979169062 3 P54709 1 +Sodium potassium exchanging atpase complex 0.7046095612082809 1.6852564126603606 0.0919391113053431 1.0 0.3568019979169062 3 P54709 1 +Myosin ii complex 0.7066956961704206 1.680205223941624 0.0929173933087414 1.0 0.3590706046507298 5 P35580,P60660,P14649 3 +Ficolin 1 rich granule membrane 0.7145942143814501 1.6715334179859145 0.0946163636604611 1.0 0.3611473791978458 19 P13473,P11279,P42785,P10253,Q93050 5 +External encapsulating structure 0.6982454607627658 1.647764402963535 0.0994010263781255 1.0 0.3707214970624048 35 P04083,P51858,P07858,Q5KU26,P07602,Q9UBB9,Q9UHI8,Q08380,Q92896,P53634,Q08431 11 +Bleb 0.6995683746344857 1.646840895611472 0.0995907530485626 1.0 0.3707214970624048 5 Q9BRK5 1 +Tertiary granule membrane 0.7061631258212517 1.6394820736439693 0.1011129010741012 1.0 0.3715772966530752 13 P10253,P27105 2 +Filtration diaphragm 0.6916494541162583 1.633183208235789 0.102430470490467 1.0 0.3721776457661592 2 P46940 1 +Blood microparticle 0.7048569892261982 1.6230788904532056 0.1045725415561524 1.0 0.376957145846684 19 P04062,P27105,P02786,Q08380 4 +Golgi associated vesicle 0.6927392078455792 1.6177096922681025 0.1057251762429427 1.0 0.3796116564313535 35 Q8TCT8,Q99523,O43493,O43731,P05067,Q8NDZ4,Q9Y287,P11717 8 +Clathrin coated vesicle 0.6505974974934039 1.6110086877780303 0.1071778288862377 1.0 0.3833183527225443 53 O15126,Q9Y6I3,Q99523,P04114,O43493,Q9NVZ3,Q04656,Q14108,Q5VW38,P98164,P42892,P20645,O43752,P11717,P02786 15 +Trans golgi network transport vesicle 0.6964565348149561 1.5847615730288696 0.1130205162364712 1.0 0.3919190525006151 16 P11717,Q99523 2 +Caspase complex 0.6872575765814596 1.5757419548590554 0.1150852843065211 1.0 0.3960670916511217 7 O43292,Q9H490,P17655 3 +Lumenal side of membrane 0.6872114760130607 1.559611639077748 0.1188516843457825 1.0 0.4059653038327853 10 Q8TCT8,P10321,P01889,P10619 4 +Neuromuscular junction 0.6895614773046428 1.5489478886700518 0.1213942476340625 1.0 0.4115671146552605 17 Q15375,Q7L0J3,P05067,P10644,Q14168 5 +Swr1 complex 0.6761592650400114 1.5293527885679254 0.1261770096458276 1.0 0.4217436102547319 6 Q96L91 1 +Fascia adherens 0.6728501988581457 1.5136661440814636 0.1301105358723719 1.0 0.429724757332893 6 P15924,P19022,P12814 3 +Mismatch repair complex 0.6678476527900818 1.5053940084307669 0.1322228085873744 1.0 0.433766911624768 4 P43246,P52701,P20585 3 +Golgi stack 0.6663084370614692 1.4964195702169265 0.1345443528484471 1.0 0.4379562470685798 38 Q9Y6B6,Q99523,O00461,O60512,Q8WVQ1,Q8NBZ7,Q9P2E5,P15291,Q8NBN3,Q10472,Q10471,Q11206,P04439 13 +Striated muscle thin filament 0.6669173718434007 1.4930630571174668 0.1354206816593635 1.0 0.4379562470685798 5 P09493 1 +Apical part of cell 0.5832211240792825 1.4740664444573437 0.1404637021296282 1.0 0.4479122249728005 66 P07858,Q13277,P30825,P08195,P54709,Q04656,P05067,P98164,O75787,P08183,P23634,P15311,Q99538,Q99808,P04083,P61421,P51790,Q9NV96,P23258,Q8TAD4,Q16181,P41440,Q8NCM8,P19022,O75955,Q13572,Q15154 27 +Coated vesicle membrane 0.6019781655760313 1.469996766958635 0.1415626296098411 1.0 0.4481499943729539 61 Q9Y6I3,P10321,Q9Y6B6,P04114,O43493,Q9NVZ3,Q14108,Q9UJU6,O43731,Q13190,P98164,P01889,P20645,Q8NDZ4,P11717,P02786,P04439 17 +Excitatory synapse 0.6633034589699652 1.4683379643941044 0.1420124433923066 1.0 0.4481499943729539 6 Q7L576,Q9UQB8,P23634 3 +Collagen containing extracellular matrix 0.6668548455290901 1.4523061906524213 0.1464164869196063 1.0 0.4557400548487403 31 P04083,P51858,P07858,P07602,Q9UHI8,Q08380,P53634,Q08431 8 +Integral component of presynaptic active zone membrane 0.656321969938525 1.442879688038419 0.1490543659418852 1.0 0.4572429618524814 5 P19022,P23634 2 +Intrinsic component of presynaptic active zone membrane 0.656321969938525 1.442879688038419 0.1490543659418852 1.0 0.4572429618524814 5 P19022,P23634 2 +Proton transporting v type atpase complex 0.6637617543378014 1.4416322580317138 0.1494061432368854 1.0 0.4572429618524814 11 Q9Y487,Q15904,P61421,Q93050 4 +Pericentriolar material 0.6548969215736807 1.4361214686990975 0.1509677801200961 1.0 0.4604769748144739 5 P23258,Q15154 2 +Neuron projection terminus 0.6630881454375401 1.422581848370637 0.1548574090367547 1.0 0.4665989458900642 15 Q9UQB8,Q13641,P51790 3 +Synapse 0.3290296670388223 1.4188677816013906 0.1559375668709752 1.0 0.4665989458900642 265 O15126,Q15375,Q9NR77,O60645,Q13277,P05556,Q15334,P08195,Q14254,P63104,Q9UQ16,Q7L576,P05067,Q13641,Q04656,Q9UJU6,Q5SQN1,O75787,P60866,P23634,O43752,P21359,P63220,Q16539,Q9Y4J8,Q9NQX3,P61586,Q14444,P12814,P50897,Q99808,Q07021,Q9BY67,P61421,P51790,P11279,Q9Y263,Q96BM9,Q7L0J3,P56545,O60333,Q86Y82,O00264,Q16352,Q14168,O15400,Q13136,P61160,Q99720,P41440,Q9UBB6,P46934,P19022,P51991,P43034,P10644,P31749,O75955,Q9BT78,Q9BPW8,O00560,Q9UQB8,P29992,Q9UL25,P55884,Q92542 66 +Recycling endosome 0.6404115076116378 1.3980322415294633 0.1621033854679163 1.0 0.4723267972739288 43 O15126,P05556,P10321,P51790,Q9H4M9,P05067,P23258,Q9H223,O14773,P01889,Q86Y82,Q8NB49,O15400,P02786,P04439 15 +Neurofibrillary tangle 0.6397167305989987 1.3903398247878034 0.1644257099860506 1.0 0.4746375501318313 2 Q13492 1 +Extrinsic component of endoplasmic reticulum membrane 0.6391265860135604 1.3875641594511876 0.1652698014731979 1.0 0.4754765266358249 2 Q15006 1 +Tertiary granule 0.6342264764004959 1.3850532714750003 0.1660361788497952 1.0 0.4757175167424116 45 Q08722,Q92820,Q8WVQ1,P13473,P11279,Q96BM9,Q13510,P27105,P42785,P10253,Q93050 11 +Intrinsic component of golgi membrane 0.6525117117464091 1.3821735255801124 0.1669184269271619 1.0 0.4757175167424116 12 Q9Y282,Q9NRB3,Q10471,Q6ZRP7,O43505 5 +Gap junction 0.6391136119310614 1.3696035101992052 0.1708107032764163 1.0 0.4827002557545122 4 Q99797,Q69YQ0 2 +Gpi anchor transamidase complex 0.6378820000369549 1.3552952564157466 0.1753235057374456 1.0 0.4904755743329766 5 Q9H490 1 +Late endosome 0.5388132922985055 1.334000447908216 0.1822037097384166 1.0 0.4960292038251819 72 P07602,O15118,Q04656,P11717,Q99538,Q14108,P20645,Q8TCT8,Q8IV08,P51790,Q9NV96,P11279,P13473,Q96BM9,O43567,O15400,Q9BRK5,Q9NQ11,P35670,P10644,Q9NUM4,Q9UN37 22 +Cilium 0.3869176353719395 1.3319768396336016 0.1828677992115948 1.0 0.4963554550029002 99 Q8TD19,Q10713,P54709,P05067,P23634,P15311,P28070,Q9H3S7,Q9P2S5,Q86SX3,Q15555,P04083,P23258,A6NIH7,Q7Z3E5,Q5SW79,Q16181,Q14203,Q9Y496,Q8NCM8,Q9H4M9,P10644,P43034,P31749,P29992,Q15154 26 +Membrane microdomain 0.5579918904375283 1.3207883082418372 0.1865719592113111 1.0 0.4981522000508344 67 P13473,O15118,Q04656,P05067,Q8WTV0,P19022,P10644,O75955,Q86Y82,O14773,Q9NWW5,P50897,P78310,P27105,O00560,P08069,P17655 17 +Recycling endosome membrane 0.6423033810031973 1.3048897829707018 0.1919303807479058 1.0 0.5064589161440723 23 O15126,P10321,Q9H4M9,Q9H223,P01889,Q86Y82,Q8NB49,P02786,P04439 9 +Phagocytic vesicle membrane 0.6406945681356891 1.304636512469172 0.1920166491427719 1.0 0.5064589161440723 29 P10321,P61421,P13473,P11279,Q04656,Q06481,P01889,Q93050,P04439 9 +Presynaptic active zone 0.6386221343184907 1.2901542005197733 0.1969971243108723 1.0 0.5118557759872239 19 P41440,Q13277,P19022,Q7L0J3,P05067,P56545,O75955,P23634,Q07021 9 +Lumenal side of endoplasmic reticulum membrane 0.6263321527515439 1.2778340293814858 0.2013079529921766 1.0 0.5186238788950991 8 Q8TCT8,P10321,P01889 3 +Cis golgi network 0.632424342421257 1.2611403784794284 0.2072582749576628 1.0 0.5269663000108981 18 O43731,Q9NPR9,O00461,Q16706 4 +Apical plasma membrane 0.6002342899452745 1.2606493799492884 0.207435199236746 1.0 0.5269663000108981 51 P07858,Q13277,P08195,P30825,P54709,Q04656,P98164,O75787,P08183,P23634,P15311,P04083,P61421,P51790,Q9NV96,Q8TAD4,Q16181,P41440,P19022,O75955,Q13572 21 +Myofilament 0.6155375020480598 1.240409253980203 0.2148240599191666 1.0 0.5373387954771963 6 P09493 1 +Presynaptic active zone membrane 0.6165012050940766 1.2375528223198984 0.2158819167433656 1.0 0.5379352679506816 7 P19022,Q13277,P23634 3 +Schaffer collateral ca1 synapse 0.6256260553812517 1.2331790350751854 0.2175089753648524 1.0 0.5405127671191974 16 Q15375,P05556,Q13277,Q9UQB8 4 +Annulate lamellae 0.6056184830869693 1.2016269014423924 0.22950811394259 1.0 0.5541006370459278 5 Q8TD16 1 +Postsynaptic density membrane 0.6108630337754115 1.1964788030069364 0.2315097656034406 1.0 0.554168767199937 9 Q15375,Q99720,P23634,Q14168 4 +Autophagosome membrane 0.6182653697826124 1.1964748837008394 0.2315112941920789 1.0 0.554168767199937 16 Q9NQ11,P13473,P11279,Q96GC9,O75787 5 +Flotillin complex 0.6057791347067744 1.1937410667768231 0.2325792709925098 1.0 0.5552677883381387 6 P41440,O75955 2 +Postsynaptic specialization membrane 0.6137754787967554 1.1873640854398542 0.2350840398982894 1.0 0.5597823613243863 13 Q15375,P19022,Q9NQX3,P23634,Q14168,Q99720 6 +Golgi transport complex 0.6011264573019025 1.1714951962528193 0.2413997875963334 1.0 0.5718353410074183 6 Q96MW5,Q9Y2V7,P60953 3 +Basal part of cell 0.5630403252278469 1.1413382307410262 0.2537291985766212 1.0 0.5844539485351253 58 P08195,P30825,P54709,Q04656,Q96N67,P23634,P02786,Q07954,P15311,P78310,P04083,Q9BY67,P15291,Q14168,P42785,P41440,P35670,P19022,O75955 19 +Proteasome core complex 0.6031478615219001 1.1253925752531884 0.2604227159518806 1.0 0.587884942940879 15 P49721,P28074,P28072 3 +Distal axon 0.5508324171615404 1.1198685007330345 0.2627698030852627 1.0 0.5907630131917077 61 O60645,Q13277,P61421,P51790,Q8TAG9,P05067,Q13641,A0MZ66,P78310,Q92859,Q99720 11 +Myosin filament 0.5806354878698045 1.0921246892189085 0.2747782988361074 1.0 0.6073004344819679 4 P35580,P35579 2 +Exocytic vesicle 0.592286226339864 1.0915827662355388 0.2750165344748385 1.0 0.6073004344819679 40 O15126,Q13277,O15400,P61421,P51790,P11279,Q7L0J3,P05067,O60333,Q86Y82,P50897,O43752,Q92542 13 +Compact myelin 0.5760337557982442 1.0801120605304746 0.2800922818588205 1.0 0.6170148817759524 3 Q8N3R9 1 +Phagocytic vesicle 0.5724984950233473 1.0737029533942757 0.2829558372609597 1.0 0.6188386656642573 50 P10321,P61421,P51790,P13473,Q9Y487,P11279,Q04656,Q06481,P01889,Q86Y82,O43752,Q93050,P04439 13 +Trans golgi network membrane 0.5963160288130137 1.067697078653503 0.2856571766469287 1.0 0.6210284106764701 29 P35670,Q04656,P05067,Q9NX62,P20645,O43752,P11717 7 +Specific granule lumen 0.5884079431084142 1.0397903109064528 0.298437331581284 1.0 0.635922538322736 18 Q99519,Q92820 2 +Smooth endoplasmic reticulum 0.5770315122758414 1.0193510215976365 0.3080363496481164 1.0 0.6440224369401427 11 P05067 1 +Perikaryon 0.5872638770506977 1.0181765018859448 0.3085940843671517 1.0 0.6440224369401427 27 Q9UBB6,Q04656,P05067,A0MZ66,P19021,Q14168 6 +Cell projection membrane 0.5144227968344695 1.0022934644725785 0.3162018781026203 1.0 0.6539140880489563 67 Q96AC1,P05556,Q14728,Q04656,P98164,Q06481,O75787,P23634,Q9HBM0,P15311,P31751,P51790,P40855,P15291,Q14168,P41440,Q9H4M9,P06756,P09493 19 +Zymogen granule membrane 0.5590291778623457 0.990061443977132 0.3221440873048329 1.0 0.6597025176059117 4 Q13277 1 +Podosome 0.5705461119118207 0.9879358159744672 0.3231840832222346 1.0 0.6597025176059117 11 Q9UJU6,P61160 2 +Platelet alpha granule 0.5769670446021502 0.9866001412468588 0.3238387009684893 1.0 0.6597025176059117 17 P05067 1 +Golgi associated vesicle membrane 0.5804803759013215 0.986140046306555 0.3240643946134303 1.0 0.6597025176059117 23 Q8TCT8,O43731,Q9Y287 3 +Basolateral plasma membrane 0.5527266905339748 0.963649651862418 0.335221604586186 1.0 0.6763763349172602 51 P04083,Q9BY67,P41440,P15311,P08195,P30825,P54709,P35670,P19022,Q04656,O75955,P15291,P23634,P78310,Q14168,P02786,Q07954 17 +Main axon 0.5648375409667057 0.9603444390739744 0.336881891306771 1.0 0.6782257944189297 11 P05067 1 +Mitotic spindle microtubule 0.561519652605912 0.9586558823146512 0.3377321305846323 1.0 0.6784398746545919 9 P23258,Q9H6D7 2 +Early endosome membrane 0.5482597601950665 0.9358373798646716 0.349356922438754 1.0 0.6891571235494582 51 P04083,P10321,Q8IV08,P51790,Q9NV96,Q9H4M9,Q04656,Q92783,Q9H223,Q06481,P01889,Q86Y82,O15400,P04439 14 +Trans golgi network 0.4905757628264161 0.9314122174398276 0.3516403734368074 1.0 0.6911552167551043 71 O15126,Q04656,P05067,P04062,P57737,O43752,P11717,O43493,Q9HAS0,P20645,P19021,Q8NB49,Q96MW5,Q9NPR9,Q9NX62,Q9HC07,P35670,O14828,Q9UL25,Q4J6C6 20 +Pseudopodium 0.5520949882556596 0.9214794552241108 0.3568001626533501 1.0 0.6982870136048398 8 P12814,P17655 2 +Ficolin 1 rich granule lumen 0.4729504588050368 0.9144143054912728 0.360499187729439 1.0 0.7001257706931309 75 P07858,Q8WVQ1,Q16539,P08236,Q13510,P16278,P68402,P15586,Q9UNP9,P61160,P07384 11 +Specific granule membrane 0.5613415424043423 0.8969905085092367 0.3697239817714153 1.0 0.7063071971845634 20 Q08722,O60784,O15126,Q9NV96,P06756,O94886,Q6IAA8,O00264,P27105,Q9BXS5 10 +Atac complex 0.5405740214540048 0.8935779238867975 0.3715477623637981 1.0 0.7066595106389022 5 Q9NRF9,Q96ES7 2 +Ciliary transition zone 0.5475194102309894 0.8843035465462684 0.3765323742959872 1.0 0.7094990193345875 10 Q15555,A6NIH7,Q15154 3 +Haus complex 0.5366306666908298 0.8654909539546567 0.3867693788572779 1.0 0.7228149047496669 6 Q9H6D7 1 +Copii coated er to golgi transport vesicle 0.5547895961238254 0.8516667487027745 0.3943990808852198 1.0 0.7340652280965724 33 O15027,P10321,Q9Y6B6,Q9Y282,P05067,Q13190,P01889,P53634,Q969X5,P04439 10 +Ciliary base 0.5310592643384215 0.8394728213654029 0.4012040344981122 1.0 0.7452099378050476 6 P10644 1 +Multivesicular body 0.541446931369655 0.8344774581561895 0.40401198474513 1.0 0.7483446271897125 13 Q9NQ11,Q9Y3E7,P11279,P10644,P13693 5 +Saga type complex 0.5311675772968419 0.8311759749404057 0.4058742249330593 1.0 0.7493062614148789 7 Q9NRF9,Q96ES7 2 +Tertiary granule lumen 0.542538589329387 0.8219805585168113 0.4110879618693146 1.0 0.7545068452585845 16 Q92820,Q13510 2 +Nata complex 0.5177095631640982 0.8080767671638606 0.4190463910767836 1.0 0.7628149873493547 3 P41227,Q9BXJ9 2 +Zymogen granule 0.5218211829707597 0.8063906480376015 0.4200176375485032 1.0 0.7630599311638145 5 Q13277 1 +Nuclear outer membrane 0.5297186535989726 0.7999271809047197 0.4237529885492443 1.0 0.7667911221367278 10 Q99720 1 +Gtpase complex 0.5228305245661031 0.7923431222651974 0.4281606341826953 1.0 0.7732326700487488 7 Q9UBI6 1 +T tubule 0.5240631015399728 0.7812719231009265 0.4346425798943227 1.0 0.7772432016933771 9 P30626,P05026,P23634,P08069,O75298 5 +Cell substrate junction 0.3062292091862143 0.768038318339222 0.4424644202068155 1.0 0.7861186632508637 182 Q96AC1,P05556,Q10713,Q14254,P63104,Q7L576,P23396,Q96N67,O15511,P11717,P07384,Q07954,P42356,P46783,P15311,Q13308,Q14108,P67936,P61586,P12814,Q9UBG0,Q15555,P04083,P23229,P62258,P43121,Q16527,Q13136,P61160,P41440,P06756,P19022,O75955,P11233,P31946,O00560,P17655,Q9UL25,Q92542 39 +Ino80 type complex 0.5136284694552785 0.7327684748942819 0.4636996519863832 1.0 0.8132578511761183 9 Q96L91 1 +Intrinsic component of peroxisomal membrane 0.5011813349084234 0.7120309061104401 0.4764456379508934 1.0 0.8292336294107153 5 O43808,Q8WVX9,Q9Y3D6,P56589 4 +Specific granule 0.5199523463206124 0.7024352551692252 0.4824077654688059 1.0 0.8348308958397552 44 Q08722,O15126,O60784,Q13277,Q92820,Q99519,P51790,Q9NV96,Q8WVQ1,P06756,Q7L576,O94886,O00264,P27105 14 +Snare complex 0.5194421413050606 0.6859597367761745 0.4927384985961904 1.0 0.8437835210386829 21 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +Copi vesicle coat 0.5051224368530237 0.6854821479325839 0.4930397220134406 1.0 0.8437835210386829 10 Q9UBF2,O14579,P35606,Q8NDZ4 4 +Cytoplasmic side of endoplasmic reticulum membrane 0.5013772248889705 0.685007692311148 0.4933390669159734 1.0 0.8437835210386829 8 Q8TCT8 1 +Neuron projection membrane 0.5027878716638318 0.6747815939795059 0.499814536022608 1.0 0.8472813542462102 10 Q9HBM0,O75787,Q14168 3 +Postsynapse 0.3039241060816127 0.6747703574121873 0.4998216760794529 1.0 0.8472813542462102 133 Q15375,P05556,Q13277,Q9UQ16,Q04656,P05067,Q9UJU6,Q9NQX3,Q14444,Q9BY67,P51790,Q86Y82,Q14168,P61160,Q99720,Q9UBB6,P46934,P19022,P31749,Q9UQB8 20 +Membrane protein complex 0.2944109230473691 0.663266399389353 0.507159952228462 1.0 0.8554759281700663 314 Q9H813,P10321,Q13277,P05556,O15111,P08195,Q9C0H2,Q9NVZ3,Q96IX5,Q9UH99,Q13190,Q5SQN1,Q9UBI6,O75787,O43752,P08069,P11717,Q92859,P02786,Q07954,O95168,O60830,Q9Y6B6,Q9H490,Q9Y3E7,O43464,P22695,P01889,Q15904,P36896,Q99595,Q93050,Q9Y6I3,P23229,O43292,O43674,P61421,Q9Y487,Q5XKP0,P62942,P00403,Q86Y82,Q8NDZ4,O15400,P04439,P41440,Q9UNN5,Q9NWR8,P14406,P06756,P19022,Q93063,Q15041,O75955,O96000,Q9P0I2,P51798,O00560,O14949,P29992,Q9BRG1,O95486,Q92572,Q92542 64 +Cytosolic region 0.4924169115407424 0.6625604924658516 0.5076120800404398 1.0 0.8554759281700663 6 Q9UQB8 1 +Receptor complex 0.5142615020779141 0.6608515367030873 0.5087075283263471 1.0 0.8554759281700663 21 Q15375,P05556,O15111,P23229,P06756,P05067,P98164,O00560,P08069,P36896,P02786,Q07954 12 +Tim23 mitochondrial import inner membrane translocase complex 0.4918128596317759 0.6598565880156608 0.5093458651275724 1.0 0.8554759281700663 6 O60830 1 +Plasma membrane raft 0.5113137019318817 0.6425245740536181 0.520532638834398 1.0 0.8662878952864435 22 P41440,P15311,Q14254,P19022,Q9UNF0,P10644,Q8WTV0,O75955,P23634,P08069 10 +Copi coated vesicle 0.5001249191122813 0.6329376955182837 0.5267743303350012 1.0 0.8701116551581954 14 P24390,P49755,O43731,Q9UBF2,Q8NDZ4,O14579,P35606 7 +Synaptic vesicle membrane 0.4984568138289209 0.6322296246564234 0.5272368419949702 1.0 0.8701116551581954 13 O43752,Q86Y82,Q7L0J3 3 +Anchored component of membrane 0.4893051724412728 0.6305491937804744 0.528335327610242 1.0 0.8701116551581954 8 P36551,Q15334,Q9NQX3,Q9ULX3,P51149 5 +Nuclear outer membrane endoplasmic reticulum membrane network 0.2940866873027008 0.627486718015956 0.5303402398297046 1.0 0.8701116551581954 332 Q6UXD5,P10321,Q99523,Q8TD16,Q15392,Q13190,P51648,O75787,Q9NZ08,Q969X5,O15027,Q12907,Q9Y6B6,Q9H490,P62857,O43909,Q14108,O43464,Q9BU23,Q10472,P01889,Q8NB49,Q15904,Q9UBM7,Q8TCT8,O43292,Q8IV08,P04114,Q13555,Q9Y282,O43731,P62942,O95772,P06493,O00264,O43567,Q9NWW5,O15260,Q5JRA6,Q99720,P48449,P04439,Q15125,Q6NUK4,Q6P179,Q96G23,Q8WVQ1,Q9UNN5,Q93063,Q15041,Q96N66,Q9P0I2,O43852,Q9GZZ9,Q96GC9,Q5BJF2,O00560,Q10471,O95486,O75915 60 +Site of polarized growth 0.4909050328004935 0.6151406560155659 0.5384618346800636 1.0 0.8784922955782075 54 O60645,Q13277,Q8TAG9,Q7L576,P05067,Q9UJU6,Q96N67,A0MZ66,P43034,Q9UBF2,P78310,O15511,Q92859,Q99720 14 +Cell tip 0.4703452345824702 0.6075683472971276 0.543473799367364 1.0 0.8850859018268499 2 P35241 1 +Copi coated vesicle membrane 0.4893237460569257 0.5906349660642704 0.5547650312532495 1.0 0.8951826820773686 13 P24390,O43731,Q9UBF2,Q8NDZ4,O14579,P35606 6 +Sarcolemma 0.5036824139312215 0.5874686879568957 0.5568889739978187 1.0 0.8951826820773686 28 P04083,P05556,P41440,P11279,P19022,O75955,P08069,Q9H9S5,Q92542 9 +Proximal dendrite 0.4629684272646848 0.5759142027854084 0.5646731751489114 1.0 0.8951826820773686 2 Q6Y7W6 1 +Filopodium 0.5021820993747343 0.5750827607865656 0.5652353263856298 1.0 0.8951826820773686 32 P05556,P06756,Q7L576,P05067,A0MZ66,P15291,Q9UQB8,P78310,Q13576 9 +Ruffle membrane 0.5011281005804661 0.5748710120648408 0.5653785360488643 1.0 0.8951826820773686 28 P05556,P15311,P31751,P51790,P06756,P09493,P23396,P61586,Q06481 9 +Presynaptic membrane 0.4926709632070837 0.5681599484918786 0.5699263645006458 1.0 0.8972731178536348 19 O60645,Q13277,Q92542,P19022 4 +Post mrna release spliceosomal complex 0.4760098289822473 0.5630208236392148 0.5734207043005026 1.0 0.9001027234458836 9 Q9ULR0 1 +Beta catenin destruction complex 0.4633786178381535 0.5456041542259923 0.58533806815365 1.0 0.9110173777691052 5 Q9UJX6,Q9HB71,P48729,P35222 4 +Exocyst 0.4652819584484291 0.5342855843946135 0.5931439642624488 1.0 0.9215456480534128 7 O60645 1 +Endoplasmic reticulum golgi intermediate compartment membrane 0.4907020437250284 0.5218332700476765 0.6017864228901244 1.0 0.9293481112394928 29 Q9Y282,Q13190,Q10472,Q96GC9,O15260,P53634,Q15904,Q969X5 8 +Lamellipodium 0.4438911245786843 0.5163584686710108 0.6056040668618183 1.0 0.9293481112394928 68 Q96AC1,P05556,Q13277,Q7L576,P05067,Q9UJU6,O15511,Q13576,Q14444,A0MZ66,Q9P2B4,P61160,P41440,P06756,P19022,O75955,P31749,Q9UHY1,Q9UQB8 19 +Stereocilium bundle 0.4583208320151771 0.5140227096511877 0.6072361132970707 1.0 0.9293481112394928 6 P43034,Q9HBM0 2 +Condensin complex 0.4579025110782894 0.5122594140141911 0.6084694660251606 1.0 0.9293481112394928 6 Q15021,Q15003,O95347,Q9NTJ3,P42695 5 +Catenin complex 0.4569903050011828 0.5084199608720287 0.6111588572038591 1.0 0.9293481112394928 6 P19022 1 +Endoplasmic reticulum exit site 0.4789227535636684 0.505200069019191 0.6134183218514331 1.0 0.9293481112394928 19 O15027,O95487,Q9Y6B6,P04114,O95486,Q92734,O94979,Q5JRA6,P04439 9 +Plasma membrane protein complex 0.4418244072509829 0.5019330862582967 0.6157145905996375 1.0 0.9312300275735812 68 P05556,O15111,P10321,P08195,Q9UBI6,P08069,Q92859,P02786,Q07954,O43464,P01889,P36896,P23229,P61421,P62942,P04439,P41440,Q9UNN5,P06756,P19022,O75955,O00560,P29992,Q92542 24 +Transport vesicle membrane 0.4851643950915187 0.5002910505224443 0.6168701547713635 1.0 0.9314330813766284 42 O15126,P10321,Q9Y6B6,Q9NV96,Q7L0J3,Q13190,Q86Y82,P01889,P19021,O43752,P04439 11 +Photoreceptor connecting cilium 0.4505607820685974 0.4815843313140862 0.6301012591223625 1.0 0.946708975814818 6 Q15555,O15078 2 +Epsilon dna polymerase complex 0.4470599117365875 0.4772544209540523 0.6331809629002614 1.0 0.94681363278789 5 Q9NRF9 1 +Eukaryotic translation initiation factor 4f complex 0.4524106076442479 0.4708885476422971 0.6377203267458271 1.0 0.94681363278789 8 P23588,Q15056,O60573 3 +Transcription factor tfiid complex 0.447272538112321 0.4680186401171484 0.6397712598235321 1.0 0.94681363278789 6 Q00403 1 +Caveola 0.4669760774128912 0.4640261788085199 0.6426289897979209 1.0 0.94681363278789 17 P41440,Q14254,Q9UNF0,O75955,Q8WTV0,P23634,P08069 7 +Outer kinetochore 0.4473015138671854 0.4588187822447935 0.6463643058584188 1.0 0.9507810434562548 7 O14777 1 +Cluster of actin based cell projections 0.4786742972304574 0.4564292939251279 0.6480813045673637 1.0 0.9517715777221186 35 P41440,P60660,P15311,Q14728,Q04656,P40855,P98164,P15291,P12814,Q9HBM0 10 +Mrna cleavage factor complex 0.4558777343531093 0.444223517804788 0.6568809907074429 1.0 0.9569895583469455 13 Q5KU26 1 +Brush border 0.4725394236502869 0.4307488626688081 0.6666509858641061 1.0 0.9652313825587504 31 P41440,P60660,P15311,Q14728,Q04656,P40855,P98164,P15291 8 +Ciliary basal body 0.4696869592064129 0.427741454790232 0.6688393650556193 1.0 0.9652313825587504 27 Q9UPT5,P15311,P28070,Q9H3S7,Q9P2S5,P31749,P23258,Q7Z3E5,Q96C92,Q15154 10 +Prp19 complex 0.445579757439812 0.4254095483707217 0.6705381466273179 1.0 0.9652313825587504 10 Q9ULR0,Q9P013 2 +Growth cone membrane 0.4254942460902962 0.422607047863606 0.6725819836147555 1.0 0.9652313825587504 2 Q9UPT5 1 +Late endosome membrane 0.4703167243666115 0.4222272643227184 0.6728591427888073 1.0 0.9652313825587504 42 Q8TCT8,Q8IV08,Q9NQ11,P51790,Q9NV96,P11279,P13473,O15118,Q14108,Q96BM9,Q9NUM4,O43567 12 +Leading edge membrane 0.4697254958231779 0.421867291888326 0.6731218852054444 1.0 0.9652313825587504 43 Q96AC1,P05556,P15311,P31751,P51790,P06756,P09493,Q06481,O75787,P23634,Q14168,Q9HBM0 12 +Ctf18 rfc like complex 0.4309217502104426 0.4123277375354059 0.6800992207563883 1.0 0.9712541776489308 5 P40937,P40938,P0CG13 3 +Cell cell contact zone 0.4632098536948658 0.4099736703962012 0.6818252620805996 1.0 0.9712541776489308 24 P41440,P05556,Q9UDY2,Q14254,P19022,O75955,Q04917,P12814,P05026,P15924,Q14126 11 +Juxtaparanode region of axon 0.425261004419219 0.4004998288710669 0.6887884094970844 1.0 0.9712541776489308 4 Q14168 1 +Prefoldin complex 0.427813037056503 0.4001627064108802 0.6890366808540112 1.0 0.9712541776489308 5 Q9NUG6 1 +Cleavage furrow 0.4449620121861032 0.3914156024106252 0.6954900613768285 1.0 0.9722044034969372 14 P35580,P05556,P11233,P61586,P35579,Q16181,Q9UL25,Q15019 8 +Myosin complex 0.4352761426518817 0.3756504122656637 0.707176807446201 1.0 0.9737192203695566 11 P14649 1 +Clathrin coat 0.4496479446243016 0.3715774029251028 0.710207516182666 1.0 0.9737192203695566 20 Q9NVZ3,P11717 2 +Ciliary tip 0.4315947276615778 0.3694045201468549 0.7118262292918283 1.0 0.9737192203695566 10 Q15555,Q9Y496,Q7Z3E5 3 +Ruffle 0.448683434185648 0.3648729542795845 0.7152062438840356 1.0 0.9737192203695566 54 P05556,P15311,Q10713,P31751,Q9Y5K6,P51790,P06756,P09493,P23396,Q7L576,Q9UJU6,Q9UNF0,P61586,Q06481,P12814,Q9UQB8 16 +Postsynaptic endosome 0.4142569094177665 0.3586539598053833 0.7198539745930967 1.0 0.9740457341675136 4 Q86Y82 1 +Eukaryotic translation initiation factor 3 complex eif3m 0.4207950386027539 0.3540083579196532 0.7233326196131229 1.0 0.975857025276876 7 P55884,O00303 2 +Actin based cell projection 0.4506411613512995 0.3400695047594606 0.7338041862967248 1.0 0.9854994960362264 48 P06756,Q04656,P05067,A0MZ66,P15291,Q9UQB8,P78310,Q13576,Q9HBM0 9 +Alpha dna polymerase primase complex 0.40781692829319 0.3349106960954287 0.7376924532870812 1.0 0.9879229330364436 4 P49643 1 +Zonula adherens 0.4014167650531345 0.3220465899303198 0.7474173994346436 1.0 0.9980156197428915 3 P14923,O60716 2 +Er to golgi transport vesicle membrane 0.4340822410472387 0.301973632411513 0.762672163480546 1.0 1.0 21 P10321,Q9Y6B6,P01889,Q13190 4 +Autophagosome 0.4406471183696765 0.2924928413793547 0.7699098324532203 1.0 1.0 29 P11279,Q96GC9,Q9NQ11,P13473 4 +Rnai effector complex 0.3988559416475652 0.283311728824684 0.7769378871571122 1.0 1.0 6 P26196,Q9UPY3 2 +Dendrite cytoplasm 0.4119595961857981 0.2790021061826788 0.7802432084235189 1.0 1.0 12 Q9UQB8,Q15334 2 +Multivesicular body membrane 0.4003716283820824 0.2708608269985783 0.7864980746332138 1.0 1.0 8 Q9Y3E7,Q9NQ11 2 +Nuclear inner membrane 0.4276146492918347 0.2708229838417429 0.7865271817045243 1.0 1.0 22 Q8IXM6,Q14728,Q9UH99,O43567,O75844,Q99720 6 +Ribose phosphate diphosphokinase complex 0.3842975206611587 0.263231381682151 0.7923722443719807 1.0 1.0 3 Q14558,P11908 2 +Intercalated disc 0.4133210353782048 0.2543638138291197 0.7992145041337895 1.0 1.0 16 P05556,P19022,Q04917,P15924,P05026,P12814,Q14126 7 +Neuron spine 0.4356131831639188 0.2509697188396723 0.8018375209304771 1.0 1.0 39 P05556,Q9UQ16,P46934,Q7L576,P05067,P61586,O75787,Q9UQB8,P23634,Q14168 10 +Axon cytoplasm 0.417470980094397 0.2212965006738353 0.8248615745031829 1.0 1.0 24 Q9Y496,O60313,Q96BM9,P43034,O60333,Q14168,Q9UL25,Q92572,P46060 9 +Cortical actin cytoskeleton 0.4235581757113732 0.2152639180518599 0.8295615593890298 1.0 1.0 31 P41440,Q15334,Q14254,P19022,Q9UJU6,O75955,P12814,P17655,Q7L5Y9,P61160 10 +Extrinsic component of cytoplasmic side of plasma membrane 0.4078733660141243 0.20270481577017 0.8393657588819052 1.0 1.0 21 Q96AC1,P31749,P61586,Q9UBI6,P29992 5 +Gator2 complex 0.3555621127176159 0.1848522048764545 0.8533449598080194 1.0 1.0 2 Q96EE3 1 +Seh1 associated complex 0.3555621127176159 0.1848522048764545 0.8533449598080194 1.0 1.0 2 Q96EE3 1 +Cell cortex 0.3060333451327722 0.1837671439070417 0.8541961324940825 1.0 1.0 95 Q96AC1,O60645,Q15334,Q14254,Q8TAG9,O94915,Q9UJU6,Q14019,P15311,P67936,P61586,P12814,Q5T0N5,P35580,P31751,P56545,Q7L5Y9,P61160,Q16181,Q14203,P41440,Q9UPT5,Q00013,P46934,P19022,P43034,O75955,Q9UHY1,P17655 29 +Microvillus 0.3978140186408925 0.1800765711594434 0.8570924554309585 1.0 1.0 19 Q13576,Q04656,P06756 3 +Rna cap binding complex 0.3655209023778422 0.1766817472880152 0.8597583788626877 1.0 1.0 6 Q7L576,O60573,P06730 3 +Pre snornp complex 0.3491735537190046 0.1580721598701924 0.8743999379810456 1.0 1.0 3 Q9NWS0,Q9Y2X3 2 +Endoribonuclease complex 0.3811198424213566 0.1532124868853132 0.8782307108233884 1.0 1.0 15 Q15631,Q5KU26 2 +Phagophore assembly site membrane 0.3419887872528712 0.1483082300132508 0.8820995205769249 1.0 1.0 2 P51149 1 +Cell division site 0.387063480207633 0.1449921788075396 0.884717046943686 1.0 1.0 19 P05556,P11233,P61586,Q9UL25,Q7L5Y9,Q16181 6 +Organelle envelope lumen 0.4095721661360781 0.1419852718853278 0.8870916391521755 1.0 1.0 38 P11717,P05067,O00584,P17655 4 +Prespliceosome 0.3659867366982035 0.1379872022448005 0.8902505319187317 1.0 1.0 11 Q9UK45,Q9Y383,P26368,Q9NQ29 4 +Immunological synapse 0.3680938846645246 0.1291457986617595 0.8972422833253773 1.0 1.0 13 P15311,P20020,P52565,P10644,O15400 5 +Myelin sheath adaxonal region 0.3376623376623396 0.1286278002452648 0.8976521676226585 1.0 1.0 3 Q8N3R9,P09543 2 +Rough endoplasmic reticulum 0.4043109435985795 0.1197023434284061 0.9047189439223358 1.0 1.0 39 P63220,P05067,Q15041,Q5BJF2,Q9UQB8 5 +Non motile cilium 0.3827470064438336 0.1192973023884565 0.9050398206206578 1.0 1.0 21 Q15555,P46821,P48426,O15078,P23258,Q16181,P29992,P35613,Q15019,Q15154 10 +Hemidesmosome 0.3398458002919232 0.1168742418026299 0.9069597103031172 1.0 1.0 5 P14923,Q96RT1 2 +Dna replication factor c complex 0.3430723780668184 0.1164164897309879 0.9073224673352944 1.0 1.0 6 P40937,P40938,P41440 3 +Spindle midzone 0.3817156923351362 0.116145156862524 0.9075375009564676 1.0 1.0 21 Q15555,P53350,Q96BM9,P05067 4 +Extrinsic component of plasma membrane 0.4040533057081679 0.1158236355495656 0.9077923181211524 1.0 1.0 41 Q96AC1,P04083,P19022,P31749,Q9UBI6,P29992,Q08431 7 +Lamellipodium membrane 0.341089507561429 0.1115726941778725 0.9111622236986854 1.0 1.0 6 P06756 1 +Endoplasmic reticulum golgi intermediate compartment 0.3986408391418186 0.1093441496096754 0.9129295301769909 1.0 1.0 55 P80303,Q9Y282,Q13190,Q10472,Q96GC9,Q02818,O15260,P53634,Q15904,Q969X5 10 +Neuron projection cytoplasm 0.3995103994312738 0.1083134994251061 0.9137470146230168 1.0 1.0 36 Q9Y496,Q15334,Q14254,O60313,Q96BM9,P43034,O60333,Q9UQB8,Q14168,Q9UL25,Q92572,P46060 12 +Centriole 0.3936821117632883 0.1044960982200517 0.9167756644989616 1.0 1.0 31 P53350,Q9Y496,Q9P2S5,P23258,Q86SX3,Q7Z3E5,Q5SW79 7 +Cop9 signalosome 0.3491622370525609 0.100833428717907 0.9196826897888029 1.0 1.0 10 Q9UBW8,Q9UNS2 2 +Ciliary plasm 0.365393068657133 0.1007651638965961 0.91973688122925 1.0 1.0 16 Q15555,P10644,Q16181,Q10713 4 +Basal dendrite 0.3204485098849208 0.0977230979224349 0.922152173850934 1.0 1.0 2 P46821 1 +Escrt complex 0.3381612548998069 0.0746749537922252 0.940473335997541 1.0 1.0 10 Q9Y3E7,Q92783,Q9BRG1 3 +Nuclear ubiquitin ligase complex 0.3526158167889995 0.0675827990394265 0.9461177484670542 1.0 1.0 16 Q9UJX4,Q9UJX5,Q9NXR7,Q9H1A4 4 +Proton transporting two sector atpase complex 0.3689656084073423 0.0675128595004232 0.9461734249825308 1.0 1.0 23 P61421,Q9Y487,Q96IX5,Q15904,Q93050 5 +Paraspeckles 0.320531757754804 0.0660697386635303 0.9473223032405048 1.0 1.0 6 P23246,P52272,Q16630,Q8WXF1,Q15233 5 +N terminal protein acetyltransferase complex 0.3145304193739007 0.0619424259613106 0.9506086813143976 1.0 1.0 5 P41227,Q9BXJ9,Q9GZZ1,Q14CX7 4 +Trapp complex 0.3091231178033751 0.0594013748162586 0.9526324180499874 1.0 1.0 4 Q8IUR0,Q7Z392,Q9Y2L5 3 +Microtubule plus end 0.3248839087548266 0.046462302339874 0.9629417799942904 1.0 1.0 10 Q15555 1 +Cul4a ring e3 ubiquitin ligase complex 0.2942739079102755 0.0414978001370911 0.9668990465814342 1.0 1.0 3 Q13619,Q92990 2 +Cortical cytoskeleton 0.3788827282933896 0.0244632598931411 0.9804830892964976 1.0 1.0 41 P41440,P15311,Q15334,Q00013,Q14254,P19022,Q9UJU6,P67936,Q14019,O75955,P12814,P17655,Q7L5Y9,P61160 14 +Cytoplasmic side of membrane 0.3767767009058643 0.0077309642753491 0.993831644409491 1.0 1.0 50 Q96AC1,Q8TCT8,O15111,P15311,P62857,P17900,O43464,P62942,P31749,Q9UBI6,P29992,P11413 12 +Aggresome 0.2893965857572399 0.0071474798123184 0.9942971847652566 1.0 1.0 7 P42566,P46060 2 +Respiratory chain complex iv 0.3048860607809988 0.0045709770383903 0.9963529006936012 1.0 1.0 11 P14406,P22695 2 +Nurd complex 0.3002070393374789 0.0037092608609363 0.997040444813634 1.0 1.0 10 Q13330,O94776,Q14839,Q16576,Q09028,Q13547,Q92769,O95983,Q8WXI9 9 +Cytoplasmic region 0.3687786304531548 0.0034092499817749 0.997279817345066 1.0 1.0 62 Q10713,Q15334,Q14254,O60313,P46060,Q15555,Q96BM9,P56545,O60333,Q14168,Q16181,Q14203,Q9Y496,Q8NCM8,P10644,P43034,Q9UQB8,Q9UL25,Q92572 19 +Chromatin silencing complex 0.2791728212703137 0.0003052040896055 0.9997564823727904 1.0 1.0 6 P25490,Q15022,O60264,Q8IXJ6,Q13185 5 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ece9286c208479cabc81babbdd1b1b6ec0a75bda --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Activin receptor complex", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC9", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCS1L", "BET1", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOLA2*", "BOLA3", "BOP1", "BPHL", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C10orf88", "C11orf54", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASK", "CASP2", "CASP3", "CBFB", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC22", "CCDC47", "CCDC85C", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPO", "CENPP", "CENPV", "CEP135", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG3", "COG4", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTBS", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1L", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM2", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPK1", "IVD", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8B", "LRRC8C", "LRWD1", "LSM14A", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "METTL15", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "OARD1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PAM", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAXX", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PDZD11", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF5A", "PHF6", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RMND1", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35A4", "SLC35B2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TACC3", "TAF15", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM63A", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC37", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNG", "TXN2", "TXNDC12", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VWA8", "WAPL", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WRAP53", "WRAP73", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF326", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ABCB1", "ACP2", "ACTN1", "ACTR2", "ACVR1B", "ADAMTS1", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANXA1", "AP1M1", "AP3S1", "APLP2", "APOB", "APP", "ARF5", "ARHGAP17", "ARHGDIA", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC9", "ARPC5", "ARVCF", "ASAH1", "ATP11C", "ATP13A2", "ATP1B1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAIAP2", "BICD2", "BSG", "C17orf75", "C19orf70", "C1QBP", "C3orf58", "CACYBP", "CADM1", "CALU", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CAPRIN1", "CBX3", "CD2AP", "CD47", "CDC42", "CDH2", "CDK1", "CEP170", "CEP290", "CERS2", "CHD4", "CHMP3", "CHPF2", "CHST12", "CHST14", "CHTF8", "CHUK", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLN6", "CNP", "CNPY2", "COG6", "COG8", "COLEC12", "COPB2", "COPE", "COPG2", "COPS3", "COPS4", "COPS7A", "CORO7", "COTL1", "COX2", "COX7A2", "CPOX", "CPSF6", "CREG1", "CSNK1A1", "CSRP2", "CTBP2", "CTBS", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTNBP2NL", "CUL4A", "CWC15", "CXADR", "CYFIP1", "DBNL", "DCTN1", "DDX6", "DHCR24", "DHCR7", "DICER1", "DNAJC10", "DNM3", "DOCK7", "DSC3", "DSG2", "DSP", "DTNA", "DYNC2H1", "EBP", "ECE1", "EHD1", "EHD4", "EIF3B", "EIF3F", "EIF4B", "EIF4E", "EIF4E2", "EIF4H", "EMC2", "EMC3", "EP400", "EPDR1", "EPHA7", "EPN1", "EPS15", "ERAP1", "ERAP2", "ERBIN", "ERGIC1", "ERGIC3", "EXOC3", "EXOC6", "EXOC7", "EXT2", "EXTL3", "EZR", "F11R", "FAF1", "FAM3C", "FAR1", "FERMT2", "FIS1", "FKBP1A", "FKBP7", "FKRP", "FLOT1", "FLOT2", "FNBP1L", "FRYL", "FUCA1", "FUCA2", "FUNDC2", "G6PD", "GAA", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GATAD2B", "GBA", "GGH", "GHITM", "GIGYF2", "GLA", "GLB1", "GLG1", "GLMN", "GM2A", "GNA11", "GNG12", "GNS", "GOLIM4", "GOLM2", "GPAA1", "GPHN", "GPR107", "GPR108", "GTF2B", "GUSB", "HAUS4", "HDAC1", "HDAC2", "HDGF", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HNRNPA3", "HNRNPM", "HS2ST1", "HSPA13", "HTRA2", "IGF1R", "IGF2R", "IMPAD1", "INA", "IQGAP1", "IQGAP2", "ISY1", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPK1", "JUP", "KDELR1", "KDELR3", "KIAA0319L", "KIF1B", "KIF3A", "LAMP1", "LAMP2", "LAMTOR1", "LGALS3BP", "LGMN", "LIPA", "LLGL1", "LMAN2", "LMF2", "LNPEP", "LRP1", "LRP2", "LSM7", "LSS", "LUC7L", "LUC7L2", "M6PR", "MAEA", 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2.864547361964121 0.0041760569944158 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 2.4567680156647397e-11 1.102140235687858e-06 7.402823185757473e-11 8.183074903921214e-09 2.6454681464607386e-07 +Serine type exopeptidase activity 5 7 2.82149691900071 0.0047800096661112 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 1.4710712710358532e-11 6.332255610474929e-08 5.543981563508339e-11 1.5409886188351435e-08 9.4206715064497e-07 +Scavenger receptor activity 4 6 2.753732895970748 0.0058919832560837 2.128640776699029 4.245145631067961 0.8895147156183107 0.1752904943890176 1.2029313295363038 0.9324780265795692 1.5451274177295422 0.2106852326062687 9.36657488913704e-05 2.3666612945957126e-05 3.74476751148508e-06 5.632723326964323e-06 0.0001575214550341 +Hexosaminidase activity 3 5 2.655459143159541 0.0079200526985572 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 4.084283999932941e-07 0.0008300469730069 9.745982190989103e-07 3.9104524570814734e-05 0.0005688349419973 +Cargo receptor activity 7 10 2.564975467886514 0.0103183100063848 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 2.100216939336844e-06 2.085404982123325e-07 2.145557710414368e-07 2.232773959812015e-07 4.205073922679249e-06 +Insulin like growth factor binding 4 5 2.5259525872750457 0.011538505219423 0.9344660194174758 2.021844660194174 -0.0078197599094386 0.3226228975087925 0.9694741124292916 1.203558032267075 1.7575061579711655 0.3231431574326459 0.0043747164980101 0.0017760204843955 0.0066572828402184 0.0385233102424958 0.0002457979454447 +Phospholipid binding 19 98 2.517258744089723 0.0118271937419998 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.0087544174918757 0.0157318056270495 0.0084671328775968 0.001123201547083 0.006361511868406 +Transmembrane receptor protein kinase activity 3 5 2.508584074249983 0.0121216118379472 1.5266990291262137 3.405339805825242 -0.2400877987855226 0.4551118965545555 1.0891190778455828 1.2141042609169368 1.2003769712866084 0.3284266388044581 0.3121781622217812 0.2106238865633207 0.371655018795122 0.1109177218711893 0.2029818831286367 +Mannose binding 2 6 2.50563134514036 0.0122232990117414 2.487864077669903 6.235436893203883 0.6101269701833572 0.2582145467051042 1.3337836904766196 0.6757998162537485 1.36750331402198 0.2531492078603038 0.0016103722783247 0.000647621121882 4.656667989155393e-05 0.0007272762906085 0.0003286021100258 +Acetylglucosaminyltransferase activity 4 6 2.461389441551311 0.0138400045853424 1.9951456310679612 5.055825242718447 -0.0810216128987761 0.3234962710075558 0.9926798720162284 1.0117225763032276 1.4217293374315634 0.2924894113397103 0.0012756447222728 0.1287528218161406 0.0023694947377154 0.0044180066438726 0.010278445998416 +Proteoglycan binding 4 5 2.457119611050448 0.0140056046246805 1.362530413625304 3.1289537712895377 0.2680687531458016 0.4279813903596159 1.1106462996140136 1.3688980509063906 1.3416152040458127 0.3356932777486967 0.0074762930075664 0.0030581061915538 0.0005309775927247 0.0006333985816127 0.0010053263520343 +Hydrolase activity hydrolyzing o glycosyl compounds 14 25 2.449708841418816 0.0142971772233897 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 8.285815331271895e-11 1.0709977112272234e-07 2.037642100992123e-11 2.163215305325967e-13 3.998615960432592e-10 +Retromer complex binding 2 5 2.422915267644448 0.0153965173705323 1.7864077669902914 4.62378640776699 0.1266826261911074 0.4322045282144987 1.2199831722291083 0.628387698804986 1.1917576639553151 0.3183570223820515 0.0016103722783247 0.000647621121882 0.002465796513642 0.014977467250991 0.0053031795330487 +Protein homodimerization activity 40 184 2.389898152315688 0.0168530456000861 33.429611650485434 168.70145631067962 0.0951830737805638 0.7760449128803 11.562720345616436 17.317164104911654 0.6447101686158003 0.3064647849610271 0.0089354156779507 0.0241632026825961 0.0014697989843356 0.0008234300323006 0.0004626563378529 +Clathrin heavy chain binding 1 5 2.3841867552511187 0.0171169133781763 0.9563106796116504 4.172330097087379 0.3682910274765735 0.3434838107739949 1.107360186700709 1.195424695125345 1.3132806864166615 0.2873136636013117 1.0 0.0385773062479974 0.002465796513642 0.014977467250991 0.0542215392640632 +Glycolipid binding 4 10 2.3501524690694504 0.0187657224501669 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 7.359319072154466e-06 0.0030581061915538 1.7352123755419733e-05 3.982551880468722e-05 7.746328029618005e-06 +Palmitoyl protein hydrolase activity 1 6 2.3419983599740517 0.0191807992083825 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0037203118650809 0.0573151884822011 0.0056684159955205 0.0331187861076589 0.1125747569923622 +Glucosidase activity 1 5 2.334238740702769 0.0195832244018974 1.674757281553398 4.980582524271845 0.3871275652038076 0.3636983138593921 1.1787123504763262 0.1379870912966203 1.1856385826834483 0.2919762169358068 0.0530076413273822 1.0 0.0653907127050202 0.011414919510753 0.0419919493306108 +Sodium ion transmembrane transporter activity 1 7 2.310782642467001 0.020844863732546 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.267821754913213 0.1788224008957527 0.3209553841799009 0.2541035375726295 0.5850817530243546 +Peptide antigen binding 3 6 2.310781444943369 0.0208449299115256 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.1101969479300293 0.0711332726649859 0.1349531130589082 0.0003774704498572 0.0048822579474643 +Antigen binding 4 8 2.307485531264064 0.0210277679227726 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.1639736616263024 0.1070183553885475 0.1993869387044997 0.0001921663686867 0.0042957165481444 +Serine type endopeptidase inhibitor activity 1 6 2.3022562487005187 0.0213207255617371 1.924757281553398 5.526699029126213 0.0879544181827763 0.5160396848581311 1.5490895194100334 1.1133635632531 1.045243956687472 0.329000705737948 0.0093067293886875 0.0038211367015083 0.014058804472369 0.0768284795296569 0.2348875720984273 +Hydrolase activity acting on glycosyl bonds 17 35 2.282295897192548 0.0224718766139877 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 1.8199560085282232e-10 5.61943025826798e-08 7.934936275994736e-11 1.1083311261187638e-12 7.564023924297488e-09 +Protein binding involved in heterotypic cell cell adhesion 2 5 2.2413786911225824 0.0250015556061333 2.2402912621359223 4.87621359223301 -0.5086090712908589 0.4094933394171666 1.241682194624664 0.884997522353895 1.1210013287262848 0.3173715969175449 1.0 1.0 1.0 0.0010713621736615 0.0076703518288617 +Carboxypeptidase activity 4 12 2.136961298358268 0.0326011395577061 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 9.305773618643868e-07 0.0002088865488349 2.722163485266692e-06 0.0002379581347217 0.0001024209024739 +Exopeptidase activity 10 32 2.1259945767169923 0.0335037111057923 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 2.845106948550864e-11 4.617858951756063e-07 2.53535679304283e-10 2.017312315690788e-07 1.4175964011897233e-07 +Calcium channel regulator activity 2 5 2.094379870935754 0.0362261544280895 1.5 4.172330097087379 0.2689652937111949 0.5103443185076099 1.1585478020818727 1.0779841884060215 0.9783837010782356 0.3135810148564817 1.0 1.0 1.0 1.0 0.0539281835546241 +Phosphatidylserine binding 3 12 2.0812407098661545 0.0374118790344186 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.0012756447222728 0.0003334624710947 0.0023694947377154 0.0044180066438726 0.010278445998416 +Structural constituent of muscle 4 7 2.0717531138454417 0.0382884712420146 2.174757281553398 5.813106796116505 0.1661949614229742 0.5170417159203786 1.3842188534663291 1.1327100667826282 0.94905945968665 0.30554266142253 1.0 1.0 1.0 0.0175758241055335 0.0042957165481444 +Peptidase activator activity 1 11 2.069146740144185 0.0385323188018567 3.1359223300970873 11.033980582524272 0.0705051228612008 0.5636696767658763 1.7615005942326416 0.954707640712387 0.8762688899555645 0.2957391193753122 0.0238386467818615 0.141543756104335 0.0354914601129098 0.1735315682069146 0.4482773855235765 +Threonine type endopeptidase activity 6 8 2.038113821304093 0.0415385512449792 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0748668240169799 1.0 0.0921025797166938 6.393058955734768e-05 5.436360967141595e-05 +Growth factor binding 9 17 2.0293350938649106 0.0424241711613015 4.310679611650485 12.949029126213592 -0.0488380105863232 0.5194853451197696 2.1509949209095054 2.534197950354086 1.057563900891323 0.317878019437427 0.0019705245028114 0.0046317187370927 0.0043038530101662 0.0013823477663658 0.0017102987040416 +Heparin binding 7 14 2.0181387909326225 0.0435768087114911 3.4344660194174756 11.91504854368932 0.417671776261347 0.5410412518682232 1.977562601051691 1.5719219414069263 0.9122022863658426 0.3149614964035694 0.0003581603538938 0.0195557545343205 0.000811364430178 0.000633861319384 0.00110124435718 +Tap binding 2 5 1.996367280986016 0.0458939595070051 1.8592233009708736 3.895631067961165 0.8127354819395453 0.3477955376218754 1.070154411615344 1.0456940556701602 1.051123567423606 0.2887299843781864 1.0 1.0 1.0 0.0004628530549595 0.0034377129995212 +Cytoskeletal anchor activity 2 6 1.9779262992703783 0.0479370215849863 1.4587378640776698 6.114077669902913 0.7031806656642005 0.4219849600096998 1.2250406607966715 1.3434833271306592 0.8879018057008594 0.290790264904966 1.0 1.0 1.0 0.0103266247469619 0.0618109910728358 +Transporter activity 45 195 1.9703421774920575 0.04879916764228 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 0.047068261118905 0.1091425618959456 0.0613412098001407 0.007891835668219 4.967881955133319e-05 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..150d478b9e552e518facaae632b81e1609f4aa30 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 1427, + "title": "Average number of proteins per term", + "value": 16.76384022424667 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..48e32b652288c3a2651387dbfeb8a318b1591cb1 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1850eb51975dab7c20f6bead37c363d8c221cf86 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,402 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase activity 0.5902657487078399 4.338249054907537 1.4362234889153667e-05 0.0202864601908999 0.0204949091868237 120 P07858,Q9UIQ6,Q8N6M0,P42892,O14773,O75976,Q9H3G5,Q9NZ08,P07384,P02786,Q9UJ14,P28070,Q99538,O43464,Q9HB40,P22695,Q9Y4E8,P55786,P53634,Q8TCT8,O43292,Q92820,P10619,P49721,P49720,Q9UHI8,P42785,Q6P179,Q13867,Q9H8M7,Q99829,Q9BYT8,Q9BT78,P17655,O75844,P28074,P28072,Q92542,Q4J6C6 39 +Amide binding 0.5018324823302897 3.307940754870843 0.0009398468988677 0.7386231813117909 0.0881787152365956 105 P10321,P07602,Q9UIQ6,Q15392,P42892,O14773,Q9Y287,P08069,Q9NZ08,Q07954,Q8WTV0,Q9Y680,P01889,P55786,Q9UNP9,O43731,Q9Y4U1,P62942,P04439,P00374,Q6P179,Q9NXR7,Q9UM22,Q9BYT8 24 +Signaling receptor binding 0.4669411384209785 3.2957279782492876 0.0009816701753873 0.7537803791531174 0.0881787152365956 177 Q96AC1,Q15375,P05556,O15111,Q9UQ16,P04062,P05067,Q9UBS4,Q9H2J4,Q92520,P23634,P08069,Q08431,Q9NZ08,Q9Y624,Q07954,Q9Y5K6,P06280,P08236,Q9Y4E8,P01889,P78310,Q92896,Q07021,O94813,P04083,Q9BY67,Q9H3F6,P04114,P23229,P51858,P62942,P04439,P41440,Q9NXR7,P06756,P46934,P26583,O75955,P46379,Q04917,O00560,P40763,P29992,Q92542 45 +Lipid binding 0.4709961939065545 3.1116800221487253 0.0018602601262385 0.9298460651199398 0.0881787152365956 151 Q96AC1,Q13277,P07602,P56589,O15118,P04062,Q06481,O14773,Q13576,Q08431,P11717,P21359,Q9H490,P28070,Q9Y3E7,Q14108,Q8WTV0,Q92783,P50897,Q9Y6I3,O60784,P04083,O43292,P04114,O95772,P61916,O00264,Q9NWW5,A6NIH7,Q8NCC3,P29375,Q9NQ11,Q99829,Q9UM22,P31749,O00560,Q9BWH2 37 +Low density lipoprotein particle receptor activity 0.991147831218648 2.9371013021284593 0.0033129586355289 0.9912214187261952 0.0881787152365956 2 P98164 1 +Lysophosphatidic acid binding 0.9757969303423836 2.871744336744639 0.0040821307365483 0.9970827755110496 0.0881787152365956 3 O14773,P50897 2 +Sulfatide binding 0.9757969303423836 2.871744336744639 0.0040821307365483 0.9970827755110496 0.0881787152365956 3 O14773,P50897 2 +Serine type carboxypeptidase activity 0.9751919669226212 2.864547361964121 0.0041760569944158 0.9974501254850164 0.0881787152365956 5 O75976,P10619,Q9HB40,Q9H3G5 4 +Sulfuric ester hydrolase activity 0.9639367055861894 2.823030136731921 0.0047572099629302 0.9988914886200316 0.0881787152365956 3 P34059 1 +Serine type exopeptidase activity 0.9654338926632534 2.82149691900071 0.0047800096661112 0.9989271411062256 0.0881787152365956 7 P10619,Q9HB40,O14773,O75976,Q9H3G5 5 +Galactosidase activity 0.9583948067276448 2.803468358854402 0.0050556192692816 0.99927740882103 0.0881787152365956 2 P06280 1 +Galactoside binding 0.9583948067276448 2.803468358854402 0.0050556192692816 0.99927740882103 0.0881787152365956 2 P06280 1 +Pattern recognition receptor activity 0.9492475656535804 2.7657607685099466 0.0056790179678092 0.9997045637253836 0.0881787152365956 2 Q5KU26 1 +Low density lipoprotein particle binding 0.9492475656535804 2.7657607685099466 0.0056790179678092 0.9997045637253836 0.0881787152365956 2 Q5KU26 1 +Lipoprotein particle receptor activity 0.9495277449822868 2.763462995503225 0.0057191576872812 0.9997211021823184 0.0881787152365956 3 P98164,Q07954 2 +Scavenger receptor activity 0.9490702812985268 2.753732895970748 0.0058919832560837 0.9997823728581852 0.0881787152365956 6 Q14108,Q07954,Q5KU26,Q08380 4 +Glucuronosyltransferase activity 0.9403778040141652 2.7254162538579445 0.0064220465982927 0.9998983336053818 0.0885433696890671 3 O43505,Q93063 2 +N acetyllactosamine synthase activity 0.938920035408676 2.7229824322331795 0.0064695498035527 0.9999050386504836 0.0885433696890671 2 O60512 1 +Dipeptidyl peptidase activity 0.9341106755522162 2.699257195571932 0.0069494445726527 0.9999523427701664 0.0885433696890671 3 P53634 1 +Ganglioside binding 0.9310342252612788 2.686386369137447 0.0072229511669739 0.9999678325524404 0.0885752635733404 3 P07602 1 +Glycosphingolipid binding 0.9310342252612788 2.686386369137447 0.0072229511669739 0.9999678325524404 0.0885752635733404 3 P07602 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.9285714285714268 2.6760687406309196 0.0074491364986466 0.9999767616670304 0.0885752635733404 3 Q86SF2,Q10472 2 +Acetylgalactosaminyltransferase activity 0.928845586064365 2.673850694462045 0.0074985827944396 0.9999783563521698 0.0885752635733404 4 Q86SF2,Q10472,Q9P2E5 3 +Hexosaminidase activity 0.9252109821944524 2.655459143159541 0.0079200526985572 0.9999881940723347 0.0885752635733404 5 P06865,P17900,P54802 3 +Copper ion transmembrane transporter activity 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9999900688985548 0.0885752635733404 2 P35670 1 +Mannosidase activity 0.9206021251475758 2.6425959260311696 0.0082273156266379 0.999992411994986 0.0885752635733404 3 O00462,O00754 2 +Rna polymerase ii ctd heptapeptide repeat phosphatase activity 0.915314251991732 2.6243791149875233 0.0086807101153221 0.9999960486454826 0.0885752635733404 2 Q05D32 1 +Beta n acetylhexosaminidase activity 0.9102486223646692 2.595206794557976 0.0094534022215682 0.9999987013339235 0.0911486822309313 4 P06865,P17900 2 +Activin binding 0.9023310711124172 2.56965457571212 0.0101799964476487 0.9999995442412738 0.0955503977379763 2 P36896 1 +Cargo receptor activity 0.9057289488650798 2.564975467886514 0.0103183100063848 0.9999996266388234 0.0956118725916309 10 Q5KU26,Q14108,Q8WTV0,P98164,Q08380,P02786,Q07954 7 +Neuregulin binding 0.8940690469164958 2.5346466424951988 0.0112560804098573 0.999999903479544 0.0965905270117545 2 P23229 1 +Insulin like growth factor i binding 0.8945969884853994 2.528456018569604 0.0114565439470724 0.9999999277301106 0.0965905270117545 4 P98164,P08069,P23229 3 +Insulin like growth factor binding 0.8948611931482502 2.5259525872750457 0.011538505219423 0.9999999357945266 0.0965905270117545 5 P98164,P23229,P11717,P08069 4 +Chloride transmembrane transporter activity 0.8917084685748022 2.5246181280635103 0.01158240710985 0.9999999397376363 0.0965905270117545 2 P51797 1 +Voltage gated chloride channel activity 0.8919716646989307 2.521248189040821 0.0116939339469988 0.9999999487002976 0.0965905270117545 3 P51797,P51790 2 +Phospholipid binding 0.5002069606518335 2.517258744089723 0.0118271937419998 0.9999999576799828 0.0965905270117545 98 P07602,Q06481,O14773,Q13576,Q08431,P21359,Q14108,Q8WTV0,P50897,Q9Y6I3,P04083,P04114,Q9NWW5,Q8NCC3,Q9NQ11,Q9UM22,P31749,O00560,Q9BWH2 19 +Transmembrane receptor protein kinase activity 0.8908252383882651 2.508584074249983 0.0121216118379472 0.9999999723387162 0.0965905270117545 5 P11717,Q15375,P36896 3 +Mannose binding 0.8908952033326518 2.5056313451403596 0.0122232990117414 0.999999976117689 0.0965905270117545 6 P11717,O75503 2 +C x3 c chemokine binding 0.8863971673059909 2.502011249769754 0.0123490000819663 0.9999999800838416 0.0965905270117545 2 P06756 1 +Aromatic amino acid transmembrane transporter activity 0.8852168781351337 2.4969794597023713 0.0125256211796576 0.9999999845699188 0.0967882833722857 2 P08195 1 +Transmembrane receptor protein tyrosine kinase activity 0.8851039130461152 2.487718472789558 0.0128565460882001 0.9999999904358768 0.0986359745583961 4 Q15375,P11717 2 +Sulfotransferase activity 0.879436527128027 2.4633072389382886 0.0137661895559535 0.9999999974337505 0.1027683639303379 4 Q7LGA3,Q8NCH0 2 +Acetylglucosaminyltransferase activity 0.8806944780163684 2.461389441551311 0.0138400045853424 0.9999999976937168 0.1027683639303379 6 O43505,Q93063,P06865,P07686 4 +Proteoglycan binding 0.8789131718842204 2.457119611050448 0.0140056046246805 0.9999999981851744 0.1027683639303379 5 P07858,Q07954,O94813,O00560 4 +Hydrolase activity hydrolyzing o glycosyl compounds 0.8698861487843077 2.4497088414188157 0.0142971772233897 0.9999999988100126 0.1027683639303379 25 O00462,Q01459,Q99519,P04066,P06280,P06865,P17900,P04062,O00754,P16278,Q9BTY2,P07686,P54802,P10253 14 +Calcium channel inhibitor activity 0.8751998649940591 2.4493625866993067 0.0143109304127799 0.9999999988334716 0.1027683639303379 3 P62942 1 +Solute cation antiporter activity 0.8746174622603441 2.446855692541122 0.0144108524899433 0.9999999989905902 0.1027683639303379 3 P51790 1 +Phosphatidylethanolamine flippase activity 0.8710534080849823 2.43636960562102 0.0148355171476153 0.999999999454266 0.1027683639303379 2 P08183 1 +Floppase activity 0.8710534080849823 2.43636960562102 0.0148355171476153 0.999999999454266 0.1027683639303379 2 P08183 1 +Glycerophospholipid flippase activity 0.8710534080849823 2.43636960562102 0.0148355171476153 0.999999999454266 0.1027683639303379 2 P08183 1 +Aminophospholipid flippase activity 0.8710534080849719 2.436369605620977 0.0148355171476171 0.999999999454266 0.1027683639303379 2 Q9NV96 1 +Flippase activity 0.8713105076741386 2.432607660069279 0.0149905342792271 0.99999999956403 0.1028437135406592 3 P08183,Q9NV96 2 +Atpase coupled intramembrane lipid transporter activity 0.8713105076741386 2.432607660069279 0.0149905342792271 0.99999999956403 0.1028437135406592 3 P08183,Q9NV96 2 +Intramembrane lipid transporter activity 0.8715677590788393 2.4293011875886195 0.0151279592859567 0.999999999642738 0.1030284175008231 4 Q96GC9,P08183,Q9NV96 3 +Retromer complex binding 0.8710345083949709 2.422915267644448 0.0153965173705323 0.999999999757913 0.1030284175008231 5 P11717,Q99523 2 +Protein homodimerization activity 0.4033532430794525 2.389898152315688 0.0168530456000861 0.999999999970724 0.1083301624834367 184 Q6YP21,O15111,P07602,P16278,Q16706,P42892,Q06481,P51648,Q9Y624,P02786,P06280,Q14108,Q9Y697,P67936,P68402,O43293,Q15070,P19623,P11413,O94813,Q8TCT8,Q9BY67,Q13555,Q8NBZ7,Q9Y4U1,Q9NWU2,O95772,O00264,Q9NWW5,P27105,O43598,P34896,Q8WVQ1,P09493,Q93063,P31749,Q9GZZ9,Q9UHY1,P40763,Q9BRG1 40 +Clathrin heavy chain binding 0.8621502245274992 2.3841867552511187 0.0171169133781763 0.9999999999800402 0.1090439079940072 5 Q07954 1 +Apolipoprotein binding 0.8558017663517536 2.3607712362548505 0.0182369765640686 0.999999999996078 0.1130072886477737 4 Q07954 1 +Glycolipid binding 0.8571683830670688 2.3501524690694504 0.0187657224501669 0.9999999999981816 0.1145467288830673 10 O14773,Q9NWW5,P50897,P07602 4 +Palmitoyl protein hydrolase activity 0.8534183035129825 2.3419983599740513 0.0191807992083825 0.999999999999006 0.1145467288830673 6 Q9UMR5 1 +Glucosidase activity 0.8507486280117955 2.334238740702769 0.0195832244018974 0.9999999999994466 0.1146974230422004 5 P10253 1 +Sodium ion transmembrane transporter activity 0.8470181251222056 2.310782642467001 0.020844863732546 0.9999999999999118 0.1186032601810139 7 Q9H2J7 1 +Peptide antigen binding 0.8463456943629558 2.310781444943369 0.0208449299115256 0.9999999999999118 0.1186032601810139 6 P10321,P01889,Q15392 3 +Antigen binding 0.8468435521406552 2.307485531264064 0.0210277679227726 0.9999999999999324 0.1186032601810139 8 Q96L91,P10321,P01889,Q15392 4 +Serine type endopeptidase inhibitor activity 0.8444183854022234 2.3022562487005187 0.0213207255617371 0.999999999999956 0.1191171632887024 6 P05067 1 +Extracellular matrix binding 0.8418014804277988 2.299474737498797 0.0214779962861482 0.999999999999965 0.1192572011686128 4 P06756,O94813 2 +Vascular endothelial growth factor receptor binding 0.8377102390085471 2.292016654298868 0.0219046821714714 0.9999999999999812 0.1193052727430907 2 Q9H2J4 1 +Hydrolase activity acting on glycosyl bonds 0.8175895702068813 2.282295897192548 0.0224718766139877 0.9999999999999918 0.1204032978194561 35 O00462,Q01459,Q99519,P04066,P06280,P06865,P17900,P04062,P08236,P16278,O75503,Q9BTY2,P07686,P54802,O00754,O43598,P10253 17 +Laminin binding 0.83228930636422 2.2627405650322956 0.0236516866480236 0.9999999999999986 0.121406319592553 3 O94813 1 +Protein binding involved in heterotypic cell cell adhesion 0.8297168404266506 2.2413786911225824 0.0250015556061333 0.9999999999999998 0.1265149640069231 5 Q08722,P78310 2 +Gamma catenin binding 0.8253336573854352 2.2268445950687425 0.0259576617915835 1.0 0.1284025647553336 4 Q14574 1 +Pre mrna 3 splice site binding 0.8223664797875474 2.22480361662724 0.0260944245122962 1.0 0.1284025647553336 2 P26368 1 +Amidine lyase activity 0.8241607716511924 2.2216498792220976 0.0263069762013283 1.0 0.1290036255645897 4 P19021 1 +Calcium dependent cysteine type endopeptidase activity 0.8166834311239151 2.1939075944319795 0.0282420533202909 1.0 0.1366149494510345 3 P17655 1 +Beta 2 adrenergic receptor binding 0.8096783712009367 2.16885214305537 0.0300939110433415 1.0 0.1426711330858867 2 P46934 1 +Frizzled binding 0.8096783712009296 2.1688521430553376 0.030093911043344 1.0 0.1426711330858867 2 O00560 1 +Er retention sequence binding 0.8028917084685574 2.1387874760805117 0.0324528842142362 1.0 0.1498714102709225 2 O43731 1 +Carboxypeptidase activity 0.810798051796297 2.136961298358268 0.0326011395577061 1.0 0.1500704069317635 12 O75976,P10619,Q9HB40,Q9H3G5 4 +Exopeptidase activity 0.7933172669968088 2.1259945767169923 0.0335037111057923 1.0 0.1513901195702497 32 Q92820,P10619,Q9UIQ6,Q9HB40,O14773,O75976,Q9H3G5,P42785,P53634,P02786 10 +Coreceptor activity 0.8004722550177031 2.1218670417201833 0.0338489048211472 1.0 0.1518942993074751 3 P06756,P05556 2 +Calcium channel regulator activity 0.7968456895680811 2.094379870935754 0.0362261544280895 1.0 0.15949515089632 5 P62942,P62258 2 +Phosphatidylserine binding 0.7987655448206026 2.0812407098661545 0.0374118790344186 1.0 0.162047093172311 12 Q08431,Q06481,Q14108 3 +Structural constituent of muscle 0.7938489085517069 2.0717531138454417 0.0382884712420146 1.0 0.164077022409474 7 Q16527,P09493,P60660,P14649 4 +Peptidase activator activity 0.7957911307009549 2.069146740144185 0.0385323188018567 1.0 0.1643516707747875 11 P05067 1 +Protein lipid complex binding 0.7870370393844958 2.055747984391781 0.0398068141218146 1.0 0.1680601294432825 4 Q5KU26 1 +Threonine type endopeptidase activity 0.7872809077831159 2.0381138213040932 0.0415385512449792 1.0 0.172304135736702 8 P28070,P49721,P49720,P20618,P28074,P28072 6 +Growth factor binding 0.7881355112878462 2.0293350938649106 0.0424241711613015 1.0 0.1728827588700826 17 P23229,Q15375,Q99523,P11717,P98164,O00560,Q92896,P08069,P36896 9 +Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication 0.7786304604486293 2.023950535735073 0.042975241458548 1.0 0.1728827588700826 3 Q14126,P15924 2 +Heparin binding 0.7857518940692572 2.0181387909326225 0.0435768087114911 1.0 0.1728827588700826 14 P51858,P04114,P05067,Q06481,Q13685,Q9UHI8,O94813 7 +Tap binding 0.7752011029245327 1.996367280986016 0.0458939595070051 1.0 0.1784487199359573 5 P10321,P01889 2 +Gpi anchor binding 0.7686933853045488 1.979084174275619 0.0478065299615737 1.0 0.1833944498707118 3 Q9H490 1 +Cytoskeletal anchor activity 0.7723633543089563 1.9779262992703783 0.0479370215849863 1.0 0.1833944498707118 6 Q9UQB8,Q8TD16 2 +Calmodulin dependent protein kinase activity 0.7679094344709361 1.9755362556080944 0.0482073244307144 1.0 0.183787879945864 3 Q13555 1 +Oxidative rna demethylase activity 0.7654175272941786 1.971086836214727 0.0487139441690513 1.0 0.183787879945864 2 Q9C0B1 1 +Transporter activity 0.3738526017656105 1.9703421774920575 0.04879916764228 1.0 0.183787879945864 195 Q9H813,P08195,Q9UBX3,Q9C0H2,P30825,O15118,P17900,P04062,Q04656,Q14728,Q7KZN9,P98164,P08183,P08069,O95168,Q9H2J7,O60830,Q6NT16,Q8WTV0,Q13423,P51797,Q8NB49,Q70HW3,Q99595,Q93050,O43674,P04114,P61421,P51790,Q9NV96,Q9Y487,Q7L0J3,Q8IXU6,P00403,P61916,Q6P4A7,Q8TAD4,P41440,Q9NQ11,Q9NWR8,Q99829,P35670,P06756,P51798,Q96GC9 45 +Adrenergic receptor binding 0.7664599940950844 1.9625783549180271 0.0496951878358356 1.0 0.1846745652128578 4 P46934,Q07021,Q15334 3 +Mitochondrial ribosome binding 0.765443107928738 1.9579522041271245 0.0502356213588073 1.0 0.1861980043610858 4 Q15070 1 +Glycosaminoglycan binding 0.7701357542337796 1.9445972094086592 0.0518234754416497 1.0 0.1901082248206535 19 P51858,P04114,P05067,Q06481,Q13685,P15586,Q9UHI8,Q07021,O94813 9 +C2h2 zinc finger domain binding 0.7594217223117922 1.9370462635848944 0.0527396883982469 1.0 0.192785530036546 3 P26368 1 +Volume sensitive anion channel activity 0.7607029591674948 1.9363609764343568 0.0528235054269723 1.0 0.192785530036546 4 Q9C0H2 1 +Protein dimerization activity 0.3592069021861641 1.9229875080462773 0.0544816187049368 1.0 0.194503849560409 240 Q6YP21,P05556,O15111,P07602,P16278,Q16706,P42892,Q06481,P51648,Q13564,Q9Y624,P02786,P06280,P06865,Q14108,Q9Y697,P67936,P68402,O43293,Q9NRF9,Q15070,P19623,P11413,O94813,Q8TCT8,Q9BY67,Q13555,P62258,Q8NBZ7,Q9Y4U1,Q9NWU2,O95772,O00264,Q9NWW5,P27105,O43598,O43709,P34896,Q8WVQ1,P09493,Q93063,P31749,Q04917,Q9GZZ9,Q9UHY1,O00560,P40763,Q9BRG1,O95831 49 +Phosphatidylethanolamine binding 0.7596783252707713 1.9197301194601628 0.0548919976946511 1.0 0.194503849560409 6 Q08431 1 +Chemokine binding 0.7569925846233185 1.9194298290249032 0.0549299589157987 1.0 0.194503849560409 4 P06756,P05556 2 +Carbon nitrogen lyase activity 0.7568543176167837 1.9125536747159737 0.0558052150083381 1.0 0.1966272637454284 5 P19021 1 +Serine hydrolase activity 0.7597767022773353 1.895410444189337 0.058038046094184 1.0 0.2034896603842768 20 P10619,Q9HB40,O14773,O75976,Q9H3G5,P53634 6 +Peptide hormone binding 0.7505702858199528 1.8900610262471431 0.058749798768086 1.0 0.2054803010834774 4 P42892 1 +Protein domain specific binding 0.370815110473942 1.881549298163056 0.0598972358101599 1.0 0.2079643686158107 187 O15126,Q9P1Z2,P05067,Q9UJU6,Q9H9B1,P98164,Q9UBI6,Q14739,Q16204,P23634,Q9UNK9,Q9Y624,Q9P258,P15311,Q9Y5K6,Q9UHI6,Q93074,P08236,P61586,O43293,P20645,P78310,Q9BY67,Q9UPY3,P51790,P13473,P11279,P62258,P41440,Q9UNN5,Q9UDY2,P46934,P26583,P10644,Q04917,P31946,Q9UQB8,P26368,Q9UN37 39 +Exogenous protein binding 0.7570424911502618 1.8800539162755217 0.0601007302002316 1.0 0.2081644223197344 16 P05556,P06756,P11279,O15118,Q14108,Q8WTV0,P78310,Q9Y624,P02786 9 +Transforming growth factor beta receptor binding 0.749349345545538 1.8780802366601712 0.060370189517811 1.0 0.2081677403665921 5 Q9Y4E8,P62942 2 +Type i transforming growth factor beta receptor binding 0.7435064935064817 1.8644995094269872 0.0622515904018328 1.0 0.2135409122678255 3 Q96AC1,P62942 2 +Threonine type peptidase activity 0.7509479674293771 1.8626403402245977 0.0625128847578557 1.0 0.2139229893272426 10 Q9UJ14,P28070,P49721,P49720,P20618,P28074,P28072 7 +Pdz domain binding 0.7494927265441811 1.8436242259331448 0.0652379229196653 1.0 0.2206031184984892 16 Q9BY67,P51790,Q9UBI6,Q9UQB8,Q9Y624 5 +Channel inhibitor activity 0.739046618963622 1.824413786122851 0.0680895393590281 1.0 0.2255400987701296 6 P62942,Q9NWR8 2 +Peptide binding 0.5922256233602119 1.821623669454448 0.0685121069660525 1.0 0.2263119829642524 74 P10321,Q9UIQ6,Q15392,P42892,O14773,Q9Y287,P08069,Q9NZ08,Q07954,Q8WTV0,P01889,P55786,Q9UNP9,O43731,Q9Y4U1,P04439,Q6P179,Q9NXR7,Q9BYT8 19 +G protein alpha subunit binding 0.7330765565291278 1.8029696563156257 0.0713929802603259 1.0 0.2342017996126094 5 P08069,P11717,P80303 3 +Calcium ion binding 0.5054987763537845 1.7993194426790078 0.071968164280437 1.0 0.2350081703162098 88 P98164,Q14257,Q9H223,P14649,O75071,P07384,Q07954,Q14574,Q9Y680,P19021,Q14126,O94813,P04083,P60660,Q8WVQ1,Q9H4M9,Q9UM22,O43852,P17655,Q9BRK5,P80303 21 +Ephrin receptor binding 0.7332760755548668 1.7924028131272205 0.0730684645108992 1.0 0.2375141204033102 7 Q15375 1 +Amyloid beta binding 0.7348296340983947 1.786668339856574 0.0739911090595566 1.0 0.2399666196090621 10 Q9Y287,Q07954 2 +Molecular transducer activity 0.7093183505389127 1.770190274133799 0.0766954489852318 1.0 0.247611777606167 41 Q08722,Q15375,P05556,Q99523,O15118,O75787,P08069,P11717,Q92859,Q07954,Q5KU26,Q14108,Q8WTV0,Q9UBG0,P20645,P36896,Q99720,P06756,P40763 19 +Aspartic endopeptidase activity intramembrane cleaving 0.7225528340785995 1.7682694423061944 0.0770158698852125 1.0 0.2480849804203123 3 Q8TCT8 1 +Protein demethylase activity 0.7160607668752379 1.7239210690322295 0.0847220932401624 1.0 0.2622525532618477 5 Q8NB78,Q7LBC6 2 +Copper ion binding 0.7228248456793016 1.7199271816668822 0.0854456788882269 1.0 0.2637259957757116 13 P35670,P19021,Q9NQ11,O60888 4 +Rage receptor binding 0.7109316107079312 1.7145659868403054 0.0864248292427745 1.0 0.2646528569301271 3 P26583 1 +Rna 7 methylguanosine cap binding 0.7154567220999972 1.7089158393113622 0.0874665400765497 1.0 0.2672692777071445 7 Q8TEQ6,Q7L576,O60573,P06730 4 +Peptidyl proline dioxygenase activity 0.710517218330417 1.7051918028108703 0.0881586583242173 1.0 0.2678740758443443 4 P13674,O15460 2 +Procollagen proline dioxygenase activity 0.710517218330417 1.7051918028108703 0.0881586583242173 1.0 0.2678740758443443 4 P13674,O15460 2 +Protein arginine omega n monomethyltransferase activity 0.7066981410445551 1.702877976133356 0.088590906378434 1.0 0.2684059944841303 2 Q99873 1 +Protein carboxyl o methyltransferase activity 0.7060212514757968 1.6918067461002737 0.0906828269189414 1.0 0.2734850741039896 3 Q9H993,P22061 2 +Gtpase inhibitor activity 0.7080790978503108 1.6866718890824974 0.0916664602779187 1.0 0.2753853448770315 5 Q13576,O94813 2 +Leucine zipper domain binding 0.697461629279795 1.652041210027396 0.0985261502386198 1.0 0.2898903430732176 3 O43293,Q9NY61 2 +Lrr domain binding 0.697461629279795 1.652041210027396 0.0985261502386198 1.0 0.2898903430732176 3 O43293,Q9NY61 2 +Udp glycosyltransferase activity 0.7073768249362464 1.6385172899704197 0.1013138302802885 1.0 0.2956540609610873 23 O60512,Q16739,Q86SF2,P06865,Q93063,Q9P2E5,P07686,P15291,Q10472,Q10471,O43505 11 +Thioesterase binding 0.6925346709943982 1.6372925467202255 0.1015693575158542 1.0 0.2957948432145389 2 P60953 1 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.702759891390857 1.6341455452096485 0.1022282934527569 1.0 0.2965389483749204 10 Q13576,P31749,Q9BWH2 3 +Calcium dependent protein serine threonine phosphatase activity 0.6916494541162375 1.633183208235692 0.1024304704904874 1.0 0.2965389483749204 2 Q13555 1 +Sodium channel regulator activity 0.6924864438638805 1.6210836257765366 0.1049997051674611 1.0 0.3020858453104175 4 P46934,Q04917 2 +Endopeptidase activity 0.589179357183215 1.611760754751657 0.1070140112711792 1.0 0.3060300482644745 69 P07858,P42892,O14773,Q9NZ08,P07384,P28070,Q99538,O43464,P22695,Q9Y4E8,P53634,Q8TCT8,O43292,P49721,P49720,Q9UHI8,Q13867,Q6P179,Q99829,Q9BYT8,P17655,O75844,P28074,P28072,Q92542,Q4J6C6 26 +Potassium channel regulator activity 0.6900320149995783 1.5949627737374543 0.1107205605960255 1.0 0.3117978290761187 6 P31749 1 +Histone h3 methyl lysine 4 demethylase activity 0.6851611429744102 1.594701929663071 0.1107789063360842 1.0 0.3117978290761187 3 Q8NB78 1 +Structural constituent of postsynapse 0.6883596874612152 1.58706747644311 0.1124973630302181 1.0 0.3152238110398812 6 P12814,Q16352,Q9UQ16 3 +Procollagen proline 4 dioxygenase activity 0.6792572556967056 1.5671040701250596 0.1170903680028918 1.0 0.3225636199616345 3 O15460 1 +Peptidyl proline 4 dioxygenase activity 0.6792572556967056 1.5671040701250596 0.1170903680028918 1.0 0.3225636199616345 3 O15460 1 +Opsonin binding 0.6790429008389933 1.5580599667055095 0.1192190335253631 1.0 0.3267152266653658 4 Q07021 1 +Ceramide binding 0.6801171517068293 1.5554019868292686 0.1198503612288071 1.0 0.3267152266653658 5 P07602 1 +Antiporter activity 0.6873624358649588 1.5518150878201702 0.1207064747486774 1.0 0.3267152266653658 12 P51790,P08195,Q9UBX3,P51798,P51797 5 +Lipoprotein particle receptor binding 0.6861410155350209 1.5499702960397648 0.1211486456534134 1.0 0.3267152266653658 11 Q07954 1 +L serine transmembrane transporter activity 0.6718796105045757 1.541118096424741 0.1232880463093599 1.0 0.3300788782053596 2 Q9H9B4 1 +Ionotropic glutamate receptor binding 0.6738092224660407 1.5256380420907305 0.1271000325081841 1.0 0.3358736044244051 5 P41440,O75955 2 +Monosaccharide binding 0.6812959703258387 1.520529464666643 0.1283779592061149 1.0 0.3373763310996795 29 P13674,Q12907,O00462,Q5KU26,O15460,O75503,P19021,P11413,P11717 9 +Carbohydrate binding 0.6411062597900271 1.5151381465212783 0.1297374230704104 1.0 0.3391720247821134 51 P13674,Q12907,O00462,Q5KU26,Q86SF2,P08236,O15460,O00754,Q16706,O75503,Q10472,Q9UBG0,P19021,Q10471,P11413,P11717,P10253 17 +L ascorbic acid binding 0.6751916149858186 1.512456472353083 0.1304177778898854 1.0 0.3392309319376662 8 P13674,O15460,P19021 3 +Collagen binding 0.676115549952278 1.51134086188464 0.1307016281833861 1.0 0.3392309319376662 9 Q9UBG0,P05556,P07858,Q32P28 4 +Calcium dependent protein kinase activity 0.6630274417232247 1.4997296270363123 0.1336844528530658 1.0 0.3449687418107142 2 Q05655 1 +Transition metal ion binding 0.3438108606518884 1.4950583424722164 0.1348992164714353 1.0 0.3468489764049337 202 Q9UIQ6,Q04656,P05067,O15460,Q9H9B1,P42892,Q06481,O75976,Q9NZ08,Q99536,P13674,Q5JPH6,Q9C0B1,Q10472,P19021,P55786,Q13472,Q8N4Q0,Q32P28,O95251,P15291,P00403,Q8NB78,Q8TAD4,Q9UHI8,Q00403,P34896,Q8NCC3,Q9NUD5,Q6P179,Q9NQ11,Q99829,O60888,P35670,Q9GZZ9,Q10471,P29375 37 +Metalloexopeptidase activity 0.678165996256533 1.488512472331796 0.1366157954120845 1.0 0.3500013286410138 21 Q6P179,Q9UIQ6,O75976,Q9NZ08,P02786 5 +Structural constituent of eye lens 0.6596614948607603 1.4751845457683677 0.1401629351530262 1.0 0.356528535585327 3 Q99797 1 +P type potassium transmembrane transporter activity 0.657125995868978 1.47208702670269 0.140997378347258 1.0 0.358012916194906 2 P05026 1 +Fibroblast growth factor binding 0.6627934735652299 1.4659137064004233 0.1426717974106801 1.0 0.3604612925366635 6 Q92896 1 +Phosphatidic acid binding 0.6604669987774275 1.4625259270376842 0.1435971448610957 1.0 0.3607625452760275 5 O60313,Q9UNF0,Q9NQ11 3 +Ion transmembrane transporter activity 0.354225666505973 1.4329655418529008 0.1518676849872167 1.0 0.3795362285057062 114 Q9H813,P08195,Q9UBX3,Q9C0H2,P30825,Q14728,Q04656,Q9H2J7,Q13423,P51797,Q93050,P61421,P51790,Q9Y487,Q6P4A7,Q8TAD4,Q9NQ11,Q9NWR8,P35670,P06756,P51798 21 +Channel regulator activity 0.6654808717289391 1.4291813989146915 0.1529521025763451 1.0 0.3815780600986793 17 Q9NWR8,P62258,P46934,P62942,P31749,Q04917,O15400 7 +Oxidized dna binding 0.6400585264509306 1.3656466108301943 0.1720499092034448 1.0 0.4146307249306454 5 P23396,P52701,P20585 3 +Sphingolipid binding 0.6390704300354693 1.3528794969019755 0.1760941304903909 1.0 0.417639989545123 6 P07602 1 +Peptide alpha n acetyltransferase activity 0.6359938557482474 1.3463129960830542 0.1782015963253553 1.0 0.4210160231064273 5 Q86UY6 1 +Metalloendopeptidase activity 0.6465170526528448 1.3405617849608948 0.1800627716962664 1.0 0.4240092000174457 15 P52888,Q10713,Q5JRX3,Q9BYT8,P22695,P42892,Q9UHI8,O75844 8 +Metalloaminopeptidase activity 0.6443051804885145 1.3374955114821674 0.1810609464354271 1.0 0.4256572826414407 13 Q9UIQ6,Q6P179,Q9NZ08 3 +Peptide lysine n acetyltransferase activity 0.639366505748111 1.3343275715121792 0.1820965254213753 1.0 0.4273877331847082 9 Q86UY6,O95251 2 +Rna polymerase ii general transcription initiation factor activity 0.6314854705589605 1.3248574950165652 0.1852184209203415 1.0 0.4326405994892525 5 Q00403 1 +Lipopolysaccharide binding 0.6320124124482775 1.3119898406716437 0.1895235624107529 1.0 0.4404725139416034 7 P28070 1 +Growth factor receptor binding 0.6399698131170649 1.3081032844363454 0.1908382796023602 1.0 0.4416242538605561 15 Q9H2J4,O00560,P05067,Q92542 4 +Primary mirna binding 0.6241130758291388 1.3074804589756406 0.1910495872651916 1.0 0.4416242538605561 3 P40763 1 +Amino acid transmembrane transporter activity 0.6337341000839637 1.3011206915936118 0.1932171462340903 1.0 0.4447110768968499 10 Q9H2J7,P08195 2 +General transcription initiation factor activity 0.625556397064506 1.2883159797660289 0.1976359927725162 1.0 0.4498031286864125 6 Q00403,P13984 2 +Enzyme activator activity 0.3400655231797943 1.272325771106695 0.2032573956849317 1.0 0.4581711259154307 105 P21359,P10619,P07602,P17900,P05067,P53634 6 +Gated channel activity 0.6325859845525419 1.2714734638810834 0.2035602619694345 1.0 0.4581711259154307 15 Q9H813,P51790,Q9C0H2,P06756,P51797 5 +Dynactin binding 0.619916845273322 1.2697610531184051 0.2041697577785912 1.0 0.4588192824410231 5 P43034,Q86VS8,Q8TD16 3 +P type transmembrane transporter activity 0.6232018374711157 1.26275267116363 0.2066780785568895 1.0 0.4622721286844536 8 P35670,Q04656,P05026,P23634 4 +Integrin binding 0.631803338265238 1.2556717185787385 0.2092350170443233 1.0 0.4656922511808911 19 Q96AC1,P05556,P23229,P06756,P78310,Q08431,Q9Y624 7 +Demethylase activity 0.6215246435295817 1.2480583486721402 0.2120096899984351 1.0 0.4687054990437312 9 Q9Y4U1,Q8NB78,Q7LBC6,Q9C0B1 4 +Single stranded dna exodeoxyribonuclease activity 0.6150772359711084 1.246700927231874 0.21250717872128 1.0 0.4687054990437312 5 Q8IV08 1 +Ubiquinone binding 0.6084390675715612 1.242966866518076 0.2138800433902126 1.0 0.4701344708885002 2 P21912 1 +High density lipoprotein particle binding 0.610135821956961 1.2413507559602002 0.2144762022063164 1.0 0.4701344708885002 3 Q8WTV0 1 +Galactosyltransferase activity 0.612505782605198 1.2259100112877548 0.2202325409800729 1.0 0.4733985131094439 6 O43505,O60512 2 +Peroxisome targeting sequence binding 0.6068476948317696 1.2257894067220043 0.220277934621353 1.0 0.4733985131094439 3 Q9NXR7 1 +Alpha catenin binding 0.6086107992391822 1.2248594859012718 0.2206281674330341 1.0 0.4734381878600597 4 P19022 1 +Ubiquitination like modification dependent protein binding 0.6091334065067161 1.2183763080597263 0.2230810040662809 1.0 0.4765517856326092 5 Q99543 1 +Histone methyltransferase activity h4 k20 specific 0.6016581611976703 1.2012303223776453 0.229661870218284 1.0 0.4840878711986577 3 O96028 1 +Fibronectin binding 0.5998946312321318 1.1928853597753428 0.2329142736542744 1.0 0.4866305541795748 3 P06756 1 +Beta catenin binding 0.6183594676510301 1.19033889870663 0.2339132178186718 1.0 0.4880031605661472 18 Q9BZK7,Q9Y5K6,Q93074,P19022,Q9P1Z2,P78310,Q86X55 7 +Zinc ion binding 0.3374029267660754 1.1811950027066558 0.2375252660338005 1.0 0.4940941029595238 149 Q8NCC3,Q9NUD5,Q6P179,Q5JPH6,Q9NQ11,Q8N4Q0,Q9UIQ6,O95251,P42892,Q8NB78,O75976,P19021,P55786,Q9UHI8,Q8TAD4,Q9NZ08,Q99536,Q13472 18 +Anion channel activity 0.6112786324685042 1.175083215402055 0.2399614250437478 1.0 0.4971978507135953 13 Q9H813,Q9C0H2 2 +Organic cation transmembrane transporter activity 0.5980699325841717 1.165664414993285 0.2437501529420538 1.0 0.5032704702189491 5 Q99808,Q70HW3 2 +Metallopeptidase activity 0.6027858511530846 1.1597774369404412 0.2461394327421509 1.0 0.5035722895426792 41 Q6P179,Q99829,Q9UIQ6,Q9BYT8,P22695,P42892,O75844,O75976,P55786,Q9UHI8,Q9NZ08,P02786 12 +Structural constituent of synapse 0.5969753800742742 1.136400258083286 0.2557890878384981 1.0 0.5184815743544556 8 P12814,Q16352,P56545,Q9UQ16 4 +Aspartic type peptidase activity 0.5925711324007847 1.1306109081811482 0.2582188942727512 1.0 0.5226643434428596 6 Q8TCT8 1 +Modified amino acid binding 0.6082194609554988 1.128928436564706 0.2589280237399021 1.0 0.5233573511003403 23 P00374,P41440,Q9Y4U1,Q14108,Q8WTV0,Q06481,Q08431 7 +Folic acid binding 0.5840920742067901 1.1181577885380245 0.2634996089209644 1.0 0.5288522390017106 3 P00374 1 +Aminopeptidase activity 0.5981034756111615 1.1003904457002336 0.2711620395324434 1.0 0.5385104891297287 15 Q9UIQ6,Q6P179,Q9NZ08 3 +Acid phosphatase activity 0.5812029018176974 1.08540621358493 0.27774178158371 1.0 0.5466312103639818 5 P54098,P11117 2 +Polysaccharide binding 0.5736205370315811 1.0788917099074058 0.280636004893573 1.0 0.5508494896604246 2 P35573 1 +Cyclic nucleotide binding 0.5812161482599887 1.0764204782139613 0.2817392479192597 1.0 0.5514978145141065 6 P41440,P10644 2 +Hexosyltransferase activity 0.5880141844100203 1.07440099041823 0.28264299879455 1.0 0.5525089853148258 41 O60512,Q16739,Q86SF2,P06865,P04062,Q9P2E5,Q93063,P07686,P15291,Q10472,Q10471,O43505 12 +Proline rich region binding 0.5805470269353653 1.0732307242753247 0.2831676086652046 1.0 0.5527772606911723 6 Q9UQB8 1 +Protein tyrosine kinase activity 0.5892240887573459 1.0667419469056605 0.2860883797410738 1.0 0.5550289502530448 13 Q15375,P11717 2 +Dynein light intermediate chain binding 0.5760443313626157 1.051778687106319 0.292901099556746 1.0 0.5625435653667249 6 Q8TD16,Q8NCM8 2 +Guanylate kinase activity 0.5732269272566457 1.0475380794360756 0.2948514790006458 1.0 0.5647692087703644 5 Q9UDY2 1 +Glycosyltransferase activity 0.5568133279394928 1.031473816475128 0.3023186806617899 1.0 0.577521763459671 54 O60512,Q16739,Q86SF2,P06865,P04062,Q9P2E5,Q93063,P07686,P15291,Q10472,Q10471,O43505,Q11206 13 +Hormone binding 0.5758207871335147 1.02020728049337 0.3076301654816153 1.0 0.5808617495968538 10 P98164 1 +Scaffold protein binding 0.5847464872154743 1.017945992112654 0.3087036230284377 1.0 0.5808617495968538 19 O15111,P17480,Q15334,P07602,P62258,Q8IWS0,Q9UQB8,P23634 8 +Thiolester hydrolase activity 0.5823433985084102 1.017701645218821 0.3088197651812585 1.0 0.5808617495968538 16 Q9UMR5 1 +Guanylyltransferase activity 0.5603422838595549 1.0165685003573457 0.3093587454054722 1.0 0.5808617495968538 2 Q9Y5P6 1 +Molecular function inhibitor activity 0.5747771488172971 1.015168447608509 0.3100255382797581 1.0 0.5813488083117146 10 P46934,P62942,Q9NWR8 3 +Oxidoreductase activity acting on ch or ch2 groups 0.5576361617049737 0.9935280028077966 0.3204527108581112 1.0 0.5908088092952515 3 Q7LG56 1 +Hsp70 protein binding 0.5758405707283205 0.98548627309021 0.3243852708141683 1.0 0.5946924936462609 16 P46379,O60884,Q99543,P02786,Q8IXB1 5 +Transferase activity transferring sulphur containing groups 0.5678521864066366 0.9683972594623996 0.332846007634032 1.0 0.6073801187899791 12 Q7LGA3,Q8NCH0,Q9NRB3 3 +Peptide n acetyltransferase activity 0.5652840686986706 0.9559427903609596 0.3391011387884881 1.0 0.6163850016967094 12 Q86UY6,O95251 2 +Mismatched dna binding 0.5536846710004415 0.9551368670623304 0.339508487269526 1.0 0.6163850016967094 5 P43246,P52701,P20585 3 +Nad retinol dehydrogenase activity 0.5449985246385467 0.9448967030349874 0.3447116149059923 1.0 0.6196582595413157 2 Q8TC12 1 +Protein containing complex binding 0.2956134536776653 0.9440275078313378 0.3451555915866016 1.0 0.6196582595413157 381 P05556,P07858,Q99523,Q8TD16,Q9UJU6,P98179,Q8IWS0,Q06481,Q13576,P08069,Q08431,P11717,Q9Y624,P02786,Q07954,P10586,Q5KU26,Q8WTV0,P67936,P68402,Q9UBG0,Q96D46,P20645,P78310,Q15070,P23588,P36896,Q07021,Q8N183,Q96HS1,P23229,P53350,P61421,P62258,Q32P28,P62942,A0MZ66,O95785,P61160,P04439,Q7Z739,Q9Y496,P06756,P09493,P46379,Q15056,O00560,P17655,Q9UN37,Q99543,Q99733 51 +Supercoiled dna binding 0.550716784719627 0.94116589251304 0.346619852474415 1.0 0.6196582595413157 5 P26583 1 +Exodeoxyribonuclease activity 0.5577252298211977 0.9405090363391948 0.3469565167298607 1.0 0.6196582595413157 9 Q8IV08 1 +Snap receptor activity 0.5677572812461666 0.9326935956106186 0.3509781925233861 1.0 0.623395200363733 19 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +Inorganic anion transmembrane transporter activity 0.5683577847132905 0.932200000432856 0.3512331752574922 1.0 0.623395200363733 20 Q9H813,Q9UBX3,P51790,Q9C0H2,P51797 5 +Cell cell adhesion mediator activity 0.5652027079457729 0.919925608817848 0.3576116353526912 1.0 0.631574014416201 19 Q08722,Q14126,Q9UQB8,P78310 4 +Rna strand annealing activity 0.5449058203705046 0.9138701638281538 0.3607850729077682 1.0 0.6340397771421 5 Q15056 1 +Dna insertion or deletion binding 0.5405978384816854 0.9036379968516292 0.3661873863739884 1.0 0.639726517864406 4 P52701,P20585 2 +Fad binding 0.5535891643914128 0.8994120327067388 0.3684332323268378 1.0 0.641946547656163 12 Q9Y4U1,Q8NB78,Q15392 3 +Signaling receptor regulator activity 0.5560478874771277 0.8879488067591733 0.374568289311977 1.0 0.6463227918357815 16 Q15375,P05067,Q92520 3 +Atpase coupled inorganic anion transmembrane transporter activity 0.5315248457407373 0.8717331671825856 0.3833539618490333 1.0 0.6527996462512776 3 P51797 1 +C3hc4 type ring finger domain binding 0.5312868949232522 0.8706313954871927 0.3839554483824279 1.0 0.653044606485965 3 P0DMV9,P11142 2 +Mismatch repair complex binding 0.5286304604486306 0.8583434055044947 0.3907028682240445 1.0 0.6590224503022595 3 P43246,P52701 2 +Mutlalpha complex binding 0.5286304604486306 0.8583434055044947 0.3907028682240445 1.0 0.6590224503022595 3 P43246,P52701 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.5404473627615826 0.8433213940486132 0.3990487208256807 1.0 0.6652889890994411 11 Q13510,Q9BX68 2 +Secondary active transmembrane transporter activity 0.5499110802215308 0.8331858660909515 0.4047399125697679 1.0 0.6692512806918411 22 Q9H2J7,P51790,P08195,Q9UBX3,P51798,P51797 6 +Clathrin binding 0.5470832936975785 0.8222386947243031 0.4109410601320926 1.0 0.6779339801254292 21 Q5VW38,Q9Y6I3,Q07954 3 +Molecular function activator activity 0.5387084549608174 0.8150125886699305 0.4150651042686686 1.0 0.6823708569025231 14 Q99543,O60884,P31749,Q8IXB1 4 +Kinase activity 0.312648122221852 0.8020036642090262 0.4225508386666929 1.0 0.6930805135372078 142 Q15375,Q8TD19,O15111,O75414,P08069,P11717,Q5KU26,Q16539,Q8TBX8,Q9HBU6,P19784,O43293,P36896,P53350,Q13555,P31751,Q9HA64,P06493,Q14168,Q9UDY2,P31749,Q9UHY1,Q13572,P46020 24 +Inorganic anion exchanger activity 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.7008452850434284 2 Q9Y6M7 1 +Cysteine type endopeptidase activity 0.5424245402139 0.7847096561086634 0.4326238199917258 1.0 0.7032095207455955 27 O43292,P07858,Q99538,Q9Y4E8,P17655,P53634,P07384 7 +Histone methyltransferase binding 0.5174086965432514 0.7761974405667482 0.4376324170673964 1.0 0.705669510161541 6 O95785 1 +Phosphatidylcholine binding 0.5228180508719258 0.7754589380480005 0.4380685200705616 1.0 0.705669510161541 9 Q14108 1 +Phospholipid transporter activity 0.5210553841398613 0.7672406743850987 0.442938433688369 1.0 0.7108535987250308 9 Q96GC9,P08183,Q9NV96 3 +Molecular function regulator 0.2959214959184926 0.7609123259590617 0.4467094358585717 1.0 0.7154369977218651 295 Q15375,O95816,P07602,P54709,Q9C0C9,P17900,P05067,Q9UJU6,Q96N67,Q96ST3,Q06481,P60866,Q92520,P23634,Q9H173,O00410,Q13576,Q02818,Q9P258,P21359,P30154,Q8IZ81,P55010,P61586,Q96QE5,Q9BTT0,P53634,Q8IXB1,O94813,Q96HS1,P04083,P51858,Q13144,P10619,P62258,Q9Y297,Q9Y263,P62942,Q68EM7,O15400,P41440,Q9UNN5,Q9NWR8,Q01105,P46934,P26583,P10644,P11234,P31749,Q04917,P31946,O60884,P80303,Q9Y3P9,Q99543 55 +Kinesin binding 0.5247721194838694 0.748395475405123 0.4542216508632366 1.0 0.7242170902590376 14 A0MZ66,O14657,O60333,Q9H4H8,Q96EK5 5 +Signal recognition particle binding 0.5063309612024918 0.7353864694479283 0.4621041598545847 1.0 0.7310672240714994 5 Q9BUN8,P49458 2 +Inorganic molecular entity transmembrane transporter activity 0.3992551971998408 0.7311904876009462 0.4646628095999108 1.0 0.7343010291241115 87 Q9H813,Q9H2J7,Q9NQ11,P51790,P08195,Q9C0H2,P35670,Q9UBX3,Q04656,P61421,Q9Y487,Q9NWR8,P06756,Q13423,P51798,P51797,Q8TAD4,Q93050 18 +Rna polymerase ii activity 0.4960165240484003 0.7205986934633428 0.4711564579423593 1.0 0.7372152033813012 2 P24928 1 +Fructose 6 phosphate binding 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.739566344102125 3 P08237,Q01813 2 +Phosphofructokinase activity 0.4973435655253804 0.7156396588689532 0.4742138786639414 1.0 0.739566344102125 3 P08237,Q01813 2 +Histone deacetylase activity h3 k14 specific 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.7501690332785181 2 Q13547 1 +Cell adhesion mediator activity 0.521325590965831 0.6951265155540517 0.4869760190584875 1.0 0.7538176931236246 21 Q08722,Q14126,Q9UQB8,P78310 4 +Sterol transfer activity 0.4959868446402471 0.6886146099099002 0.4910658246141903 1.0 0.7567504662251076 5 P61916 1 +Sh3 domain binding 0.5122302105267874 0.6766455904775001 0.4986308456687178 1.0 0.7642816506651562 16 Q68EM7,P98164,Q16204,Q9Y5K6 4 +U4 snrna binding 0.4928592557228633 0.6645419741474066 0.5063434934940849 1.0 0.7711335808068935 6 Q8TEQ6,P55769,O43172 3 +Phosphodiesterase i activity 0.4837662337662172 0.6551959468552015 0.5123416035837018 1.0 0.7794365333837341 3 P27695,P22413 2 +Transition metal ion transmembrane transporter activity 0.4941965455165202 0.6525048012740928 0.514075576550773 1.0 0.7804104763169712 8 P35670,Q04656 2 +Alpha actinin binding 0.4825855962219595 0.6499923266351306 0.5156971781936073 1.0 0.7812100565629273 3 Q8WX93,Q96HC4 2 +Muscle alpha actinin binding 0.4825855962219595 0.6499923266351306 0.5156971781936073 1.0 0.7812100565629273 3 Q8WX93,Q96HC4 2 +Ribosomal large subunit binding 0.4912012241820391 0.6479299672429261 0.5170302473539499 1.0 0.7820096367968433 7 Q96D46,P98179 2 +Retinal dehydrogenase activity 0.479197403363827 0.6460738908538642 0.5182315032712252 1.0 0.7820096367968433 2 O94788 1 +Sulfur compound binding 0.5053719473985467 0.6459672697787563 0.5183005524196382 1.0 0.7820096367968433 48 P51858,P04114,P05067,Q9NRB3,Q06481,Q13685,P15586,Q9UHI8,O94813,Q07954 10 +Myosin binding 0.4899600839995977 0.6165876762289039 0.5375067252185355 1.0 0.8056954799231619 10 P61586,Q9HBM0,P11233 3 +Histone binding 0.3869140364290448 0.6153385561916097 0.538331159918225 1.0 0.8060845385134388 87 Q9BZK7,P49321,Q9H0U9,O15164,Q8IWS0,P33993,Q9Y4E8,Q9ULM3,Q9BTT0,Q7Z4V5,O95251,Q5VTR2,Q8NB78,Q86X55,P55209,Q9BUR4,Q01105,Q92688,P29375,Q99543,Q96ES7,Q13185,Q99733 23 +Protein kinase a regulatory subunit binding 0.4833918659839387 0.6042227304516142 0.5456955706103745 1.0 0.8144491070394138 8 P15311,Q9Y6W5,Q92667,Q9ULX6,Q9H3P7 5 +Membrane insertase activity 0.4804707337421534 0.5913101492373912 0.5543126305156334 1.0 0.8222496088833772 8 Q9P0I2 1 +Ubiquitin like modifier activating enzyme activity 0.4787823710278919 0.5838760288313214 0.5593037218440409 1.0 0.8270740011103072 8 Q13564 1 +Molecular adaptor activity 0.2940020642884431 0.5764894670720621 0.5642843872588965 1.0 0.8335753836629869 118 Q13277,Q8TD16,P56589,P54709,Q7KZN9,Q9UH99,Q9H1A4,Q13190,Q5SQN1,O43752,Q13619,Q9UHI6,Q13620,P05026,Q96D46,Q9BXS5,Q9Y297,Q6IAA8,Q86Y82,Q9BT73,O15400,Q16181,Q9UDY2,Q96T76,O00560,Q99747,Q9UQB8,P40763,Q13616,P55884,Q92542 31 +Voltage gated anion channel activity 0.473192188828374 0.5684191629778254 0.5697503813974363 1.0 0.8373159570073548 7 P51797,P51790 2 +Mhc protein complex binding 0.4745509722416317 0.5653416549294827 0.571841401166602 1.0 0.8389467111411836 8 Q9NUQ9,P62258 2 +Protein kinase a catalytic subunit binding 0.4698467020220828 0.5632185062836815 0.5732861026463119 1.0 0.839917113425346 6 P10644 1 +Dna clamp loader activity 0.4716737501697895 0.5618265771999679 0.5742341824512889 1.0 0.840443259854348 7 P40937,P0CG13,P40938,P41440 4 +L amino acid transmembrane transporter activity 0.4726123227220171 0.5568978240430548 0.577597241405476 1.0 0.8444992453746047 8 P08195 1 +Carboxylic acid binding 0.496748041398512 0.5496206415821053 0.58257959799358 1.0 0.8502584703757327 37 P00374,P13674,P41440,Q13277,P07602,Q9UM22,Q32P28,O15460,P19021,P11717,P34896 11 +Cysteine type peptidase activity 0.4839014004470061 0.5221688506632183 0.6015527719476692 1.0 0.8726540860136919 48 O43292,P07858,Q92820,Q13867,Q9H8M7,Q99538,Q8N6M0,Q9Y4E8,P17655,P53634,P07384 11 +Atpase coupled cation transmembrane transporter activity 0.4809318872240534 0.5199894546554645 0.6030709250613144 1.0 0.8726540860136919 18 P35670,Q04656,Q9NQ11 3 +Quaternary ammonium group binding 0.4734597742324683 0.5199168449033603 0.6031215342041047 1.0 0.8726540860136919 13 Q14108 1 +Adenylyltransferase activity 0.460896790726931 0.5155965450654354 0.6061362238473083 1.0 0.8728116967004126 7 Q9NQX3 1 +Identical protein binding 0.278593274461002 0.510175803428798 0.6099283022903086 1.0 0.8765032098371303 509 P07602,P05067,P42892,Q06481,P11717,P02786,P06280,Q14108,P19021,P53634,O94813,Q8TCT8,Q9BY67,Q8NBZ7,P07686,Q5VTR2,Q9NWW5,P27105,Q8WVQ1,Q9UM22,Q93063,P31749,Q9UQB8,Q9BRG1,Q9BRK5,P16278,Q9H173,Q9Y624,Q8TBX8,P61457,Q9GZT8,Q15070,Q9H3F6,Q9NWU2,O14777,P60604,O43598,Q16181,P09493,Q15041,O14657,O00560,P40763,Q6YP21,Q16706,Q16204,P08069,O43395,Q9Y697,Q9NQX3,P68402,O43293,P62258,Q9Y4U1,O95772,P23258,Q15125,Q9H4M9,P19022,Q9UHY1,P31946,O15111,O95816,Q9UH99,P51648,P13674,O43464,P67936,Q9Y4E8,P19623,P11413,Q15631,Q15555,P53350,Q13555,O00264,P34896,Q13867,Q99829,Q96RR1,Q04917,Q9GZZ9 82 +Lipid transporter activity 0.4806602077794029 0.4978169203510603 0.6186130887781682 1.0 0.8836445222086546 22 P04114,O15118,P17900,P61916,Q96GC9 5 +Tau protein kinase activity 0.449069973427815 0.4959287364096583 0.619944690768294 1.0 0.8846610737263554 4 O75116,P49840,Q13464 3 +Monooxygenase activity 0.4582975453171061 0.4867872390372634 0.6264091144788895 1.0 0.8921016031550651 9 P19021 1 +Map kinase kinase activity 0.4508007457775711 0.4825786026232804 0.6293949750950052 1.0 0.8954602487144292 6 Q16539 1 +Ccr5 chemokine receptor binding 0.4387724992623255 0.4753295100256804 0.6345521285337976 1.0 0.899611969393565 2 P42224 1 +Cholesterol binding 0.4620417924578829 0.470406262290637 0.6380647909245907 1.0 0.902396884687206 13 P61916,Q14108 2 +Lys48 specific deubiquitinase activity 0.4446520147671385 0.4673880155827392 0.6402222953394996 1.0 0.9025806579456764 5 Q9Y4E8 1 +Intermediate filament binding 0.4389020070838313 0.4649970781537808 0.6419335489958709 1.0 0.9025806579456764 3 P58107,P08670 2 +Ccr chemokine receptor binding 0.4389020070838206 0.4649970781537386 0.641933548995901 1.0 0.9025806579456764 3 P42224,O43776 2 +Chaperone binding 0.4764680546916507 0.4649186054296674 0.6419897461912134 1.0 0.9025806579456764 45 O95816,Q14108,Q04656,P98164,P01889,O60884,P53634,Q8IXB1,P02786 9 +Monocarboxylic acid binding 0.464144474193099 0.451692723941169 0.6514903606591642 1.0 0.9132384525153512 17 P07602 1 +Vitamin transmembrane transporter activity 0.4421453514213306 0.4470919108781802 0.6548086993279636 1.0 0.915192961744372 6 P04062 1 +Tau protein binding 0.4600199219685936 0.4404407425175976 0.6596179218022511 1.0 0.9174218074189204 16 Q99538,O95816 2 +Glutamate receptor binding 0.4412843188485454 0.4252573597285905 0.6706490739449809 1.0 0.9282407648103664 8 P41440,O75955,P23634,Q9UQ16 4 +Voltage gated channel activity 0.4472957771094532 0.4241875597954441 0.671429032634373 1.0 0.9284197960942348 11 P06756,P51797,P51790 3 +G quadruplex rna binding 0.424018884626734 0.4168718761624374 0.6767721255144163 1.0 0.9322549723364894 2 Q06787 1 +Protein carrier chaperone 0.4454966525847048 0.4168121655285154 0.6768158033220764 1.0 0.9322549723364894 11 Q15070,Q9P0I2 2 +Steroid binding 0.4602709611900559 0.4115375315965963 0.6806784266240022 1.0 0.9339693411465876 21 P61916,O15118,Q14108 3 +C methyltransferase activity 0.4201829448214822 0.4020821580616971 0.6876235630632095 1.0 0.9398839315049808 2 Q96P11 1 +Sterol transporter activity 0.4378809707544048 0.3942820682274952 0.6933728007364324 1.0 0.9407194434012628 10 P61916,O15118 2 +Adenyl nucleotide exchange factor activity 0.4356968702094623 0.3940980405006484 0.6935086576440985 1.0 0.9407194434012628 9 Q9H173 1 +Atpase regulator activity 0.4356968702094623 0.3940980405006484 0.6935086576440985 1.0 0.9407194434012628 9 Q9H173 1 +Mirna binding 0.4386342734951582 0.3810242486211618 0.7031852555284148 1.0 0.9493333582204804 12 P67809 1 +Atpase activator activity 0.4400892340490422 0.3791165222634822 0.7046013375423028 1.0 0.9503460384431628 13 P54709,Q99543,O60884,Q8IXB1 4 +Sterol binding 0.4449233364158861 0.3770805213287334 0.7061137663053967 1.0 0.9514866331612852 16 P61916,Q14108 2 +Cytidylyltransferase activity 0.4182996635445444 0.373845950578191 0.7085189305208484 1.0 0.9538268998615572 4 Q96BW9,Q8NFW8 2 +Dna translocase activity 0.4107406314547068 0.3664590028987823 0.7140225990377211 1.0 0.9592714150488376 2 P46100 1 +Peptidase regulator activity 0.4585152164533416 0.3633758603321388 0.716324131821592 1.0 0.959807076159072 32 Q06481,P05067 2 +Organic acid transmembrane transporter activity 0.4485890988461138 0.3615281723642811 0.7177046485943965 1.0 0.9598542957302756 21 Q9H2J7,P08195,P30825,Q9UBX3,P08183 5 +Protease binding 0.4527888411666607 0.3483996715885459 0.727540049128687 1.0 0.9687741045435316 28 P41440,P05556,P07602,Q9Y3E7,P06756,Q96RR1,O75955,P46379 8 +Cytokine receptor binding 0.447597163427246 0.3469409330327542 0.7286356942144532 1.0 0.9687741045435316 23 Q96AC1,Q9NXR7,P62942,Q9Y4E8,Q9H2J4,O00560,Q9NZ08 7 +Rna cap binding 0.4265267059988109 0.3414733869767777 0.732747236302203 1.0 0.9699724547339922 11 Q8TEQ6,Q7L576,O60573,P06730 4 +Fk506 binding 0.4164325627732069 0.3376130851556949 0.7356547800907822 1.0 0.9705503239333622 7 Q9Y680 1 +Macrolide binding 0.4164325627732069 0.3376130851556949 0.7356547800907822 1.0 0.9705503239333622 7 Q9Y680 1 +Mdm2 mdm4 family protein binding 0.4139574992497519 0.3375662681299379 0.7356900655933474 1.0 0.9705503239333622 6 P61927,P60866 2 +K48 linked polyubiquitin modification dependent protein binding 0.4093325457767304 0.3303969480739609 0.7411000472685707 1.0 0.9744988620989508 5 Q04323,Q92890,Q8TAT6,P55072 4 +Ubiquitin specific protease binding 0.4165610619013353 0.329172780897345 0.742025095241905 1.0 0.9744988620989508 8 Q9Y3E7,P46379 2 +Mhc class ii protein complex binding 0.412870293132444 0.3244222969222857 0.7456183413204303 1.0 0.9744988620989508 7 P62258 1 +Phosphoserine residue binding 0.4115556310638457 0.3196000754272976 0.7492715171875757 1.0 0.9764479041339456 7 P46934,P62258 2 +Active ion transmembrane transporter activity 0.4449401059653427 0.3067428922563747 0.7590390792582407 1.0 0.9815416182009112 47 Q9H2J7,P41440,P61421,P08195,P51790,Q7KZN9,Q9NQ11,P35670,Q04656,P00403,P51798,P51797 12 +Intramolecular transferase activity 0.4193435156084331 0.3062153328549635 0.7594406988622506 1.0 0.9815416182009112 12 P48449 1 +Vinculin binding 0.4016538688718184 0.3028015774989693 0.762041081155082 1.0 0.9815416182009112 5 Q9Y490,P12814,Q9Y3I0,P46939 4 +Metal ion transmembrane transporter activity 0.4425881835654459 0.3007628832389669 0.7635953135187916 1.0 0.9815416182009112 29 Q9H2J7,P08195,P35670,Q04656,Q8TAD4 5 +Organic acid binding 0.4427034819141193 0.2980488346166817 0.7656658917569643 1.0 0.9825586578571835 30 P00374,P13674,Q13277,Q32P28,O15460,P19021,P11717,P34896 8 +Hydrolase activity acting on ester bonds 0.2785426449347365 0.2897063832746598 0.7720408725138501 1.0 0.9854224732354778 186 Q8NCC3,Q8IV08,Q8NHP8,P34059,P11117,Q9NX62,O00584,P50897,P15586,Q9UMR5,Q9HAT2,Q05D32 12 +Cadherin binding involved in cell cell adhesion 0.4075832885439958 0.2712057772412558 0.7862327698475047 1.0 0.9935249040164668 11 Q9UQB8 1 +Glucose binding 0.3941557598432552 0.267136906981165 0.7893637521355266 1.0 0.9935249040164668 6 P11413 1 +Endopeptidase activator activity 0.3907265209687035 0.2650772290532058 0.7909499686377184 1.0 0.9935249040164668 5 P61289,Q16186,Q06323,O00487 4 +2 oxoglutarate dependent dioxygenase activity 0.4122656513480662 0.2648756282172055 0.7911052738162483 1.0 0.9935249040164668 14 P13674,Q9C0B1,Q32P28,O15460,Q7LBC6 5 +Ribose phosphate diphosphokinase activity 0.3842975206611587 0.263231381682151 0.7923722443719807 1.0 0.9935249040164668 3 Q14558,P11908 2 +Diphosphotransferase activity 0.3842975206611587 0.263231381682151 0.7923722443719807 1.0 0.9935249040164668 3 Q14558,P11908 2 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.3943756339659384 0.2589843158239553 0.7956473419088459 1.0 0.9935249040164668 7 Q6ZRP7 1 +Cytokine binding 0.3912668144222219 0.2573715119905064 0.7968919924545887 1.0 0.9935249040164668 6 P06756 1 +Nadp binding 0.4163776374697138 0.2521235045121581 0.8009456027071038 1.0 0.9935249040164668 18 Q9UBM7,P00374,Q13423,Q14739,P35270,P11413 6 +Alcohol binding 0.411780863131521 0.2487748622197466 0.8035349369421225 1.0 0.9935249040164668 16 P61916,Q14108 2 +Nad dependent protein deacetylase activity 0.3783943329397889 0.2440364359918089 0.8072026009812996 1.0 0.9935249040164668 3 Q13547,Q92769 2 +Importin alpha family protein binding 0.3833431777909102 0.2406774826066918 0.8098050923108775 1.0 0.9935249040164668 5 Q9ULW0,Q14974,P62826,Q08379 4 +Protein deacetylase activity 0.3785060525538891 0.2346906576246507 0.8144488393794918 1.0 0.9935249040164668 4 Q13547,Q92769,O94776 3 +Nucleobase containing compound kinase activity 0.4155836434655848 0.2306980486513156 0.8175493895911354 1.0 0.9935249040164668 21 Q9UDY2,Q5KU26,Q14168 3 +Deoxyribonuclease activity 0.4113088265248794 0.2272004857955044 0.8202678499619962 1.0 0.9935249040164668 19 Q96QE5,Q9BQP7,Q8IV08 3 +Nadplus adp ribosyltransferase activity 0.3786178381571258 0.2255450521844305 0.8215552815272118 1.0 0.9935249040164668 5 Q9UGN5,P09874,Q9ULX3,Q7Z2W4 4 +Histone acetyltransferase binding 0.3786178381570976 0.2255450521843408 0.8215552815272815 1.0 0.9935249040164668 5 P42224,P04637,O95905,P12004 4 +Pre mirna binding 0.3741878322504441 0.2117118147139039 0.8323318702238585 1.0 1.0 5 Q9H2U1,O75569,Q9UPY3,P62826 4 +Anion transmembrane transporter activity 0.4254587260788449 0.2109611062084728 0.8329176210628224 1.0 1.0 47 Q9H813,P08195,P30825,Q9C0H2,Q9UBX3,P51790,P51798,P51797 8 +Centromeric dna binding 0.3681724239740224 0.2027491476039572 0.8393311066357598 1.0 1.0 4 P43246,O43264,Q99661 3 +Acetyl coa hydrolase activity 0.3630460448642337 0.1969407771115291 0.8438738829985586 1.0 1.0 3 O14734,Q9Y305 2 +Endopeptidase regulator activity 0.4136991184153209 0.1927485722514714 0.847155881494422 1.0 1.0 27 P05067 1 +Oxidoreductase activity acting on a heme group of donors 0.373371238500057 0.1914914383641533 0.8481405876249475 1.0 1.0 7 Q7KZN9 1 +Glucosyltransferase activity 0.3832061743585757 0.1816064798855616 0.855891563205379 1.0 1.0 12 P04062 1 +Enzyme regulator activity 0.2688067217584684 0.1815421202651859 0.8559420751814264 1.0 1.0 230 P07602,Q9C0C9,P17900,P05067,Q9UJU6,Q96N67,Q06481,P60866,Q02818,P23634,O00410,Q13576,Q9P258,P21359,P30154,Q8IZ81,P55010,Q96QE5,Q9BTT0,P53634,O94813,Q96HS1,P04083,Q13144,P10619,Q9Y297,Q9Y263,Q68EM7,P41440,Q9UNN5,Q01105,P10644,P31749,P31946,P80303,Q9Y3P9 36 +Dipeptidase activity 0.3599609363796193 0.1787420068803163 0.8581402835720477 1.0 1.0 4 Q8IYS1 1 +Manganese ion binding 0.3960176116438672 0.1740581093793417 0.8618197944661035 1.0 1.0 19 P15291,Q10472,Q9NQ11 3 +Phosphoprotein binding 0.4058325241747567 0.1639622498460904 0.8697608618220658 1.0 1.0 27 P62258,Q9Y297,Q9Y4P3,P46934,O15344,P43034,Q8IWS0,P31946,P11717 9 +Nuclear import signal receptor activity 0.377225914535476 0.1632154066138588 0.8703488361413985 1.0 1.0 12 O00410,O60518,Q9UI26,Q8TEX9 4 +Four way junction dna binding 0.3569435746418777 0.1524949185314543 0.8787965979916588 1.0 1.0 6 P26583,P52701 2 +Microtubule plus end binding 0.3668023291379116 0.1479416246925143 0.8823888378723406 1.0 1.0 10 Q15555,Q14203 2 +Translation initiation factor binding 0.3875111612567873 0.1464078468119277 0.8835994332000277 1.0 1.0 19 Q13144,P55010,Q9Y4P3,Q9UNK9,P55884,O00303 6 +Regulatory rna binding 0.3780641014711594 0.1439494665628427 0.8855403737543741 1.0 1.0 15 Q14671,Q9UPY3,P67809 3 +Protein transporter activity 0.3826126193296021 0.1375314326796649 0.8906107491127564 1.0 1.0 18 P98164,O60830,P08069 3 +Sulfur compound transmembrane transporter activity 0.3509754541552836 0.136505372638899 0.8914217775567661 1.0 1.0 6 Q9UBX3 1 +Cyclosporin a binding 0.3625175548465765 0.1359254673562479 0.8918802022800041 1.0 1.0 10 Q96BP3,Q9UNP9 2 +Ubiquitin like protein conjugating enzyme activity 0.3561320479316026 0.1263264536224757 0.8994735170338708 1.0 1.0 9 Q9C0C9,P60604 2 +Protein macromolecule adaptor activity 0.295349531137451 0.1231975237284394 0.9019506864109011 1.0 1.0 96 Q13277,Q8TD16,P56589,P54709,Q9UH99,Q13190,Q5SQN1,O43752,Q13619,Q9UHI6,Q13620,P05026,Q96D46,Q9BXS5,Q9Y297,Q86Y82,O15400,Q9UDY2,Q96T76,O00560,Q99747,Q9UQB8,P40763,Q13616,Q92542 25 +Histone methyltransferase activity 0.3750664875142492 0.1214634834751512 0.9033239364752488 1.0 1.0 17 Q86X55,O96028,Q9H9B1 3 +Translation repressor activity 0.3526869562679141 0.1173018420522925 0.9066208653632966 1.0 1.0 9 P00374,Q5PRF9 2 +Atp dependent protein binding 0.3311688311688375 0.1131749665402264 0.9098918419421338 1.0 1.0 3 P08238,Q9UBE0 2 +Ribosomal small subunit binding 0.355957111390308 0.1107797924018641 0.9117909700341518 1.0 1.0 11 Q15056 1 +Phosphatidylinositol phosphate binding 0.3944204084779029 0.1070068532059225 0.9147835429030542 1.0 1.0 31 O00560,Q9NQ11,P31749,Q9BWH2 4 +Annealing activity 0.3485476984722708 0.1067765273640304 0.9149662694467766 1.0 1.0 9 Q15056 1 +Signaling receptor complex adaptor activity 0.3354529358377556 0.1064083540354876 0.91525836514912 1.0 1.0 5 Q96T76,Q06124 2 +G protein beta gamma subunit complex binding 0.337370753323489 0.1027028469568457 0.9181988140510032 1.0 1.0 6 P08754,Q14344,P41208,P29992,P04899 5 +Transcription regulator inhibitor activity 0.3246753246753259 0.098568828713917 0.9214806205435324 1.0 1.0 3 Q96ST3,Q00577 2 +Omega peptidase activity 0.385977631306298 0.0969167943598944 0.9227924716214786 1.0 1.0 27 Q9Y4E8,Q9UJ14,Q92820,Q8N6M0 4 +Uridylyltransferase activity 0.317497786957801 0.091517892715297 0.927081089565446 1.0 1.0 2 Q16222 1 +Misfolded protein binding 0.3588433114645118 0.0900182128845228 0.9282727417968384 1.0 1.0 15 P48723,Q9UBS4,P46379,Q8IXB1 4 +Atpase binding 0.3885845064845227 0.0874938976237534 0.9302789358221772 1.0 1.0 31 P15311,P55769,P54709,Q9Y487,P11234,P40855,P11233,Q9BUN8,P05026,Q9NUM4,Q92542,Q8IXB1,Q93050 13 +P type calcium transporter activity 0.3212316561847829 0.083110149344287 0.933763955758657 1.0 1.0 4 P23634 1 +Thyroid hormone receptor binding 0.3414025102204313 0.0821210792710351 0.9345504309027036 1.0 1.0 10 Q00403,Q93074 2 +Manganese ion transmembrane transporter activity 0.316410861865412 0.0812118580209296 0.9352734693304136 1.0 1.0 3 Q9HD20,Q9HC07 2 +Map kinase scaffold activity 0.3182757602598256 0.0770479529689638 0.9385853973625428 1.0 1.0 4 O60271,P46940,P36507 3 +Palmitoyltransferase activity 0.3207324276432451 0.0741928163165444 0.940856961847578 1.0 1.0 5 O15270,P50416,O15269,P23786 4 +Cyclin binding 0.3466498650017938 0.0732944809463395 0.941571783456189 1.0 1.0 13 O14777,P06493 2 +Phosphatidylinositol bisphosphate binding 0.3527801503699628 0.0615186591413338 0.9509461547038128 1.0 1.0 17 Q9NQ11 1 +Microfilament motor activity 0.3247999885393755 0.0602627576558651 0.9519463630980513 1.0 1.0 8 P35580,P60660 2 +Hydrolase activity hydrolyzing n glycosyl compounds 0.3344091485079548 0.0593269997165181 0.952691656320754 1.0 1.0 11 O43598 1 +Protein kinase c binding 0.3358521517811961 0.0555782598481137 0.9556777838576598 1.0 1.0 12 Q07021 1 +Heat shock protein binding 0.3866846764116097 0.0457978463944149 0.963471375339748 1.0 1.0 50 Q12907,Q9UNN5,O95816,P46379,P06493,O60884,Q99543,P48723,Q8IXB1,P02786 10 +Protein self association 0.3318052894817632 0.0402945296759211 0.9678583149251634 1.0 1.0 13 P53634 1 +Atpase coupled transmembrane transporter activity 0.3682132956174864 0.0393455869601827 0.9686148615967288 1.0 1.0 28 Q9NQ11,P61421,P35670,Q04656,P51798,P51797 6 +Phosphatidylinositol binding 0.3800661860829706 0.0326727637474819 0.9739355436720258 1.0 1.0 57 O60784,Q9H490,Q9NQ11,Q8WTV0,P31749,Q92783,Q06481,O00560,Q9BWH2,Q13576 10 +Carbohydrate derivative transmembrane transporter activity 0.3145541350110965 0.0270519971134539 0.9784182614870384 1.0 1.0 10 P41440,Q99808,Q8TB61,Q6KCM7 4 +G rich strand telomeric dna binding 0.291789722386304 0.0236467613222647 0.9811343724243846 1.0 1.0 5 P22626,P15927,P09651,Q15554 4 +Transcription corepressor binding 0.3223779204019731 0.0217653403568321 0.9826351420219676 1.0 1.0 13 O95785,P51858,Q9H9B1 3 +Tubulin binding 0.2442897893543091 0.0198929733224333 0.9841287505137556 1.0 1.0 105 Q86VS8,Q8NBT2,Q9UQ16,O60313,P23396,Q9UH99,Q8IWS0,Q9H4H8,Q96DB5,Q9P258,O95239,P15311,Q15555,P53350,O43292,Q96BM9,P60520,O60333,O75381,Q6NUK4,Q14203,Q9Y496,O15078,P43034,Q9H6D7,Q9Y3P9 26 +Single stranded telomeric dna binding 0.2918759231905497 0.0169615952643143 0.986467253900636 1.0 1.0 6 Q92878,P09651,Q15554,P22626,P15927 5 +Abc type transporter activity 0.3030374290630043 0.0143492795082956 0.9885513243068992 1.0 1.0 9 Q9NQ11 1 +Nucleoside diphosphate kinase activity 0.293134022478037 0.0123438694821635 0.990151267230648 1.0 1.0 7 O75414 1 +Phospholipase binding 0.2772364924712265 0.0108653835971865 0.9913308487559698 1.0 1.0 4 P84103,P43034,P07196 3 +U3 snorna binding 0.2984869501615661 0.0074315067836606 0.9940705700515932 1.0 1.0 9 Q9NX24,Q2NL82 2 +N acetyltransferase activity 0.3244944194490954 0.0069365385124975 0.9944654873982008 1.0 1.0 16 Q86UY6,O95251 2 +Lysine n methyltransferase activity 0.3050201686707939 0.0047792852316577 0.9961866966189636 1.0 1.0 11 O96028,Q9H9B1 2 +Histone lysine n methyltransferase activity 0.3050201686707939 0.0047792852316577 0.9961866966189636 1.0 1.0 11 O96028,Q9H9B1 2 +Smad binding 0.322416078246923 0.0031306651993102 0.9975020946527836 1.0 1.0 16 Q9Y4E8,P36896,P62942 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7fa517eb6f6eaf6406cbf69932aa971c82211ad6 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylesterase activity", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin activated receptor activity", "Activin binding", "Activin receptor activity type i", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta galactoside cmp alpha 2 3 sialyltransferase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C c chemokine binding", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding protein binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chitinase activity", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chondroitin sulfotransferase activity", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co receptor binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled chemoattractant receptor activity", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione hydrolase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "Hypoglycin a gamma glutamyl transpeptidase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inhibin binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Mechanosensitive ion channel activity", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on metal ions", "Oxidoreductase activity acting on metal ions nad or nadp as acceptor", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Short chain carboxylesterase activity", "Sialyltransferase activity", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein serine threonine kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific endopeptidase activity", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL8A", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCS1L", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C11orf54", "C1QBP", "C1orf123", "C1orf35", "C20orf27", "C2CD2L", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPV", "CEP135", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1L", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GID8", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIC2", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCRL", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAIP2", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PAXX", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDRG1", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOK2", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD5", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TES", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM38B", "TMEM43", "TMEM63A", "TMEM70", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS36", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VWA8", "WARS", "WARS2", "WASF2", "WBP11", "WBP2", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WRAP53", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF638", "ZNF644", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "AATF", "ABCB1", "ACBD3", "ACOT8", "ACOT9", "ACP2", "ACTN1", "ACTR2", "ACVR1B", "ADAMTS1", "ADRM1", "AGL", "AIFM1", "AKAP1", "AKAP8L", "AKT1", "AKT2", "ALDH1A2", "ALDH3A2", "ANAPC1", "ANGEL1", "ANP32B", "ANP32E", "ANXA1", "AP1M1", "APEX1", "APLP2", "APOB", "APP", "ARHGAP17", "ARL6IP1", "ARL8A", "ARMT1", "ASAH1", "ATP11C", "ATP13A1", "ATP13A2", "ATP1B1", "ATP1B3", "ATP2B4", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "ATRX", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG6", "BAIAP2", "BICD2", "BLMH", "BTRC", "BUD23", "C1QBP", "CADM1", "CALCOCO1", "CALU", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CARM1", "CBX3", "CCDC6", "CD2AP", "CD47", "CDC42", "CDH2", "CDK1", "CEP290", "CETN2", "CHMP3", "CHPF2", "CHST12", "CHST14", "CHTF8", "CHUK", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLN6", "CMAS", "COLEC12", "COPS4", 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"NHP2", "NIF3L1", "NLN", "NMD3", "NME6", "NNT", "NOB1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NRBP1", "NSD2", "NSUN5", "NUCB1", "NUCB2", "OPA1", "OTUD6B", "OXA1L", "P3H1", "P4HA1", "P4HA2", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PALLD", "PAM", "PARP1", "PARP2", "PCBD1", "PCMT1", "PCNA", "PDCL3", "PDLIM5", "PEX14", "PEX19", "PEX3", "PFKM", "PFKP", "PGAM5", "PGRMC1", "PHF6", "PHKA1", "PIGU", "PIP4K2C", "PITRM1", "PLA2G15", "PLAA", "PLBD2", "PLD3", "PLK1", "PM20D2", "PMPCA", "POLE3", "POLG", "POLR2A", "PPIE", "PPP2R1B", "PPT1", "PPT2", "PPWD1", "PRCP", "PREPL", "PRKAR1A", "PRKCD", "PRKRA", "PRMT1", "PRPF3", "PRPF4", "PRPS2", "PRPSAP1", "PSAP", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMD14", "PSME1", "PSME3", "PSMG3", "PTPN11", "PTPRF", "PUM1", "PURA", "QSOX2", "RABGAP1", "RAD50", "RALA", "RALB", "RAN", "RANBP6", "RBM3", "RCC2", "RCN2", "RDH11", "REEP3", "RFC3", "RFC5", "RHOA", "RMDN1", "RNASET2", "RNF20", "ROCK1", "ROCK2", "RPA2", "RPL37", "RPS20", "RPS3", "RRM2B", "RTCB", 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1.9487627742005753 0.3762024781602087 3.801766469053063e-07 0.0001846255682838 6.228062066369426e-07 2.378617385793337e-06 8.863294718010003e-06 +Cognitive impairment 52 177 3.442716469002832 0.0005759027553065 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 3.724871144181224e-05 0.0014182344860646 5.3354567317574624e-06 3.624190656544229e-05 0.0001464766100991 +Splenomegaly 20 94 3.437505083944127 0.0005870996980974 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 6.976754623382056e-05 0.0262221556449147 7.179090621618829e-05 1.930654252416485e-07 0.0003506759345603 +Abnormality of the lymphatic system 29 153 3.403660194060196 0.0006648941240614 29.699029126213592 145.21601941747574 0.1994066708674118 0.5892027724934705 8.709814742221091 14.879269336886908 1.105110161252099 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skin 26 107 3.091548777430144 0.0019911526565024 22.009708737864077 100.32766990291262 0.4385550996860712 0.6098739890089617 6.832596267878453 10.09935648280444 0.8592900670649001 0.3543867989618216 0.158304246608586 0.0432872408847351 0.0461727917944619 0.0025591357023613 0.0407369800398178 +Abnormal systemic arterial morphology 26 151 3.022692227225994 0.0025053690635761 26.512135922330096 139.09223300970874 -0.0457047476890588 0.6345296488429398 8.296820557307836 14.036057514403687 1.004196439476248 0.3481529181225943 0.0028769295943545 0.1199184951243544 0.0038781101594324 6.529012172817231e-05 0.0021172983449188 +Vascular skin abnormality 35 124 2.987662313986738 0.0028111997491382 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.1346849619395093 0.0069666957324518 0.0064033501357934 0.0008977676296208 0.0017393820314914 +Abnormal vascular morphology 56 240 2.9505603284595487 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1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 6.006028410542415e-09 1.0515666421094113e-07 1.795667029584697e-08 1.8654270901726772e-06 5.436360967141595e-05 +Abnormality of the upper respiratory tract 19 107 2.779351805057006 0.0054467500069801 19.66504854368932 95.80582524271844 0.4534569687157453 0.5959175600884278 6.924659870205313 10.36312380503997 0.9632839800839448 0.3651113920771414 0.0792746039976939 0.1767081432445665 0.0653061147287855 0.0009006104431447 0.0174763623312821 +Abnormal anterior eye segment morphology 95 329 2.7638281694367777 0.0057127614237166 57.866504854368934 302.6432038834951 0.0602914657910268 0.8598549040402009 17.40171134362565 32.39967903213882 0.4649778666136724 0.2483313692740211 0.2368941607335263 0.4323548853215823 0.1345214133797337 0.0218444621202116 0.0090338085404498 +Abnormal vertebral morphology 34 120 2.7501746427051854 0.0059563509840174 25.18446601941747 107.1383495145631 0.7050611944944222 0.5078087978506296 8.434496402822974 10.278065304429203 1.0858158093436174 0.3796440707216367 0.101063390951964 0.2053566616012395 0.0337323180421229 0.0007848814755165 0.00017335396163 +Cherry red spot of the macula 7 10 2.7448871039567715 0.0060531717482663 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 1.5885570109980076e-10 2.3666612945957126e-05 5.957935356591728e-10 4.9852358185053743e-11 1.2165707930957296e-08 +Posteriorly rotated ears 26 121 2.7230987792024672 0.0064672717749478 22.179611650485437 108.6504854368932 0.4817735830108808 0.6409255719604446 7.3320530406518625 12.346894376126524 0.7519045403366967 0.3519188615999026 0.1211165581624408 0.2298054416284537 0.106556093656772 0.1221845420301422 0.0636914230374056 +Abnormality of the alveolar ridges 2 6 2.69717344343453 0.0069930836181355 2.1092233009708736 6.368932038834951 1.3424122348723253 0.2105791674194365 1.182482323454481 1.3741037061958896 0.9200079991465796 0.2386077675723682 0.0210218377513724 0.1330370821365251 0.031373049189738 0.0326106125072858 0.1645088237572309 +Somatic sensory dysfunction 16 112 2.693741363549544 0.0070654967854815 20.62621359223301 103.13106796116504 0.4616647154578088 0.6224901145055866 6.697057188310742 11.252715134072538 0.8145956960114787 0.3487626343279149 0.0044490599033121 0.0408778717457478 0.0040104826371672 0.0292685101622192 0.0102166927868062 +Oligosacchariduria 5 7 2.687676391960608 0.0071951088947825 2.4611650485436893 4.978155339805825 0.0914492290535993 0.2254706360721404 1.281286747781515 0.9537908500181173 1.6653598868357138 0.2594196870884814 0.0016103722783247 0.0385773062479974 4.656667989155393e-05 5.243287226084708e-09 3.274702614006158e-07 +Dysostosis multiplex 7 10 2.664741397637618 0.007704754621693 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 1.8075608697867588e-05 0.0981765691424607 4.236608354872846e-05 1.6944596929924012e-08 3.3887188864580013e-06 +Neurofibrillary tangles 3 5 2.65349510897151 0.0079662925082564 1.9878345498783456 4.347931873479319 0.5966090900062281 0.2642083372508564 1.0995898071170882 1.1496807364853057 1.4348037417662018 0.2714513638042118 0.0050782941261834 0.0020655426456597 0.0002902447274798 0.0002821754852333 0.003721367796782 +Generalized abnormality of skin 52 234 2.6485623508587968 0.0080834936549065 42.28883495145631 215.60922330097088 0.1545055431556074 0.7736907944679371 13.6061654928698 21.51935711085951 0.6198657801519588 0.3029543125181065 0.3679887824603315 0.0881839451296923 0.0404250155198762 0.0061145573419296 0.0013334957717976 +Abnormal morphology of the conjunctival vasculature 3 8 2.636068781741983 0.0083872728468412 2.6359223300970873 7.330097087378641 0.3791669082255805 0.3264494094231241 1.4642904354684148 1.4524057679745994 1.3542312898692437 0.2989163062985944 0.0003967304077019 0.0038211367015083 2.7844996115802127e-05 0.0009927961558234 0.0118865434534573 +Abnormal bone structure 44 187 2.621952259801236 0.0087427676860891 37.41747572815534 174.03398058252426 0.5052466892255619 0.6451089511590872 11.181012226303604 17.857684720378465 0.8786021869184294 0.373142151762858 0.097946090151239 0.1019557706737291 0.1149526533167171 0.003000641794322 0.0016405357211752 +Abnormal sternum morphology 37 123 2.6173687997550807 0.0088610545345779 25.42233009708738 110.19174757281552 0.4566971760702576 0.6169838687654687 7.431648826430472 11.361219588504673 0.8416956950389548 0.3481564624731069 0.7128898909132805 0.7967312730748517 0.3678300586898117 0.0239595257409011 0.037355598479188 +Abnormal abdomen morphology 32 231 2.6134328301236533 0.0089637701596678 45.24757281553398 217.06796116504853 0.263799574584816 0.6764915980447229 15.11659760776178 20.132335067264993 0.8853741103367009 0.356409600882342 0.0018411309560813 0.103890978784807 0.0011634008575592 1.7523872980918363e-05 0.0010034254713347 +Abnormal respiratory system morphology 45 318 2.6108519027244337 0.0090316996637505 56.359223300970875 301.3883495145631 0.0104738603706509 0.8532437948990974 18.717939253084875 28.979816548398137 0.5386766463479802 0.252805304775745 0.0383597625397044 0.063789577484503 0.0096749333839096 0.0084314519331142 0.0604286248034693 +Abnormal thorax morphology 55 244 2.5969585591517483 0.0094053270602565 45.70873786407767 223.58495145631068 0.1329293284361508 0.8464208669117267 12.555609173113975 23.25116275926513 0.4910267466787029 0.2593045889961468 0.5512723115255981 0.827226985880386 0.4108160900875782 0.0358306674994575 0.0161216958457334 +Urinary glycosaminoglycan excretion 5 8 2.590251056320043 0.0095905959889057 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.000190495704273 0.0023758658868836 1.0100053103379697e-05 8.117802851328154e-07 4.367834065541858e-05 +Abnormality of skin physiology 21 96 2.57596493224836 0.0099960783727921 17.75 93.7864077669903 -0.1755474696041827 0.6575486487430307 7.290313096743081 8.883988526805158 0.7639004808690326 0.3169080454135924 0.3272755240308372 0.1345945251337754 0.0390233204365771 0.0017121454927469 0.0079219247500136 +Increased head circumference 31 127 2.572221042520873 0.0101048352561552 23.478155339805824 116.06553398058252 -0.0533057786142688 0.7503797170911747 8.864240832088646 14.533626107123467 0.604743886171867 0.2823650812468278 0.0667107234985568 0.2721363862669712 0.1452966026827366 0.0186035523475973 0.1330597092991795 +Abnormal uvea morphology 38 107 2.5554732500924224 0.010604351151142 21.303398058252423 98.10922330097088 0.1007882775181369 0.7748938399032084 7.703402860922317 12.544105194269296 0.5554732629122807 0.2698240362881412 0.5563709140035895 0.8455713123288128 0.7012230967827482 0.4223716101338258 0.5459494345203013 +Abnormality of the tongue 26 101 2.541972934356191 0.0110228708819517 22.424757281553397 89.52912621359224 0.5421010507218363 0.5607339999720974 6.938472222740965 9.436122816051313 0.9593463898963266 0.3606735981467843 0.0588308637530456 0.740817890060099 0.1195914885469169 0.0064505829236232 0.0125149752992154 +Ovoid vertebral bodies 3 7 2.49365188146098 0.0126436478919682 2.6237864077669903 7.359223300970874 0.2693483252678329 0.2925663833748981 1.3659227234427256 1.183251804829311 1.455225024558189 0.2873440473038876 0.0113156335852872 0.0981765691424607 0.0010099703116007 0.0014755138450769 0.017002584405276 +Respiratory tract infection 24 165 2.4766341817322512 0.0132627761173673 31.961165048543688 154.9247572815534 -0.0309374230085403 0.763779894552921 11.83250609906496 14.144595478548242 0.6464492457046819 0.2912737781338448 0.0178723836569172 0.158846258608436 0.0081652807361529 0.0175119951932411 0.1016198274647094 +Anarthria 1 7 2.473791604697713 0.0133687653241643 1.3131067961165048 6.509708737864078 0.7919989281491029 0.3725746548429688 1.0710321028305447 0.7679267970658434 0.9858894880388938 0.2988917867777952 1.0 1.0 0.1180585699575878 0.0385233102424958 0.1289341732663725 +Short nose 14 106 2.468117358968025 0.013582578023183 19.189320388349515 94.86893203883496 0.1801167049822232 0.7327617441894673 8.652575940834868 9.166067955894736 0.6919426913174317 0.3117253151047744 0.0110389374133709 0.0304145205249448 0.008632132186118 0.0343575425967005 0.0473276221172757 +Endocarditis 3 5 2.4618331376729508 0.0138228959464268 1.6699029126213591 5.055825242718447 1.0315066990472646 0.3137673633075574 1.128951309195931 0.7031759081548564 0.9300019606367588 0.2935479974969262 1.0 1.0 1.0 0.0026581093268102 0.0019884945269669 +Periventricular white matter hyperintensities 2 8 2.458670473969508 0.0139452551701213 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.000190495704273 4.844157765872774e-05 0.0003602808960722 0.005208827916976 0.0048822579474643 +Abnormality of the biliary system 32 123 2.455104301644425 0.014084371657328 24.728155339805824 113.4878640776699 0.4226772043353868 0.5416117734931738 8.513489210598458 10.938368752781027 1.0946055307638114 0.3805906621326833 0.0509274391599527 0.1345945251337754 0.0390233204365771 0.0017121454927469 0.0001536150155911 +Hypersplenism 3 8 2.447781446694255 0.0143738815040144 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 0.0066298507200763 0.0027067874988798 0.0100519320580488 0.000493734331549 0.0062633876942655 +Abnormal heart sound 2 5 2.4139465516034284 0.0157807770880398 1.6262135922330097 5.065533980582524 0.0895700854459297 0.4481870945716114 1.1828434692827956 1.0014923118961363 1.1311355032809087 0.3141022336032418 0.2021881519424126 1.0 0.2445730022705269 0.0326106125072858 0.1645088237572309 +Abnormality of mouth size 29 128 2.4133089588579937 0.015808412804428 23.902912621359224 120.93203883495146 0.0949850693868571 0.7915467385618227 8.455496934529673 13.076148995104834 0.5226721233897851 0.2693528821869388 0.2475436000313303 0.4798558086889039 0.0946642147396363 0.0138052420698422 0.0163577726917244 +Thoracolumbar kyphosis 3 7 2.410534159981355 0.0159291795466782 1.8762135922330097 5.849514563106796 -0.0433205251067179 0.4491555311782494 1.27398054922956 1.0056513888059488 1.0319013374075297 0.2716578297771126 1.0 1.0 1.0 0.0042425564235442 0.003721367796782 +Motor deterioration 1 6 2.393059946848008 0.0167085108987832 1.3907766990291262 5.179611650485437 0.1463978452048765 0.3866087159912587 1.3016838902501162 0.4944074070400956 1.163792695642709 0.2820064237403191 0.0043747164980101 0.0619434524836269 0.0066572828402184 0.0385233102424958 0.1289341732663725 +Aplasia hypoplasia involving the sinuses 1 5 2.384551007049407 0.0170999772928059 1.825242718446602 4.677184466019417 -0.2307280600919181 0.5288077540541937 1.204177070374582 0.7821825544567966 0.9153090558876916 0.2984676701849995 0.0891620654695603 0.0573151884822011 0.1094892401774078 0.0331187861076589 0.1125747569923622 +Abnormal subcutaneous fat tissue distribution 2 5 2.3788534671795305 0.017366577971378 0.8883495145631068 3.354368932038835 0.5708666805516985 0.4925682297865177 0.9280735837576116 0.7245054153688981 0.906409269541909 0.3163413681181936 1.0 1.0 1.0 0.1788587842302525 0.0053031795330487 +Aplasia hypoplasia of the abdominal wall musculature 2 6 2.374238359538246 0.0175851942420017 1.980582524271845 5.084951456310679 -0.2941172899595095 0.5946501672510873 1.308898466133281 1.375961004884913 0.7739483548600558 0.293628893230155 1.0 1.0 0.2297987482657219 0.1392702662277763 0.1410707299584872 +Abnormal visual fixation 4 8 2.3728796487539463 0.0176500139314765 2.1237864077669903 6.516990291262136 0.3282606812074232 0.2644845064785266 1.2333226229346623 1.2136771814929264 1.4687997702265556 0.2650474123539905 0.0003359589954632 0.0847528009868792 0.0006327439593496 0.0007989256016515 0.0013369974246366 +Abnormal macrophage morphology 5 8 2.3718814003210533 0.0176977704866683 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 0.1171014210767626 1.0 0.0100519320580488 1.2724933964024938e-06 6.703246650942136e-05 +Abnormality of the neck 43 185 2.362617293310017 0.0181463980784519 34.13106796116505 167.26941747572815 -0.0509285658251984 0.804373887487248 11.940276371606007 17.057946263505073 0.5316163009634547 0.2670897320998164 0.8866213416487333 0.907057356971811 0.6711526203239596 0.1125172056609779 0.0080268029319504 +Abnormal cervical spine morphology 1 5 2.354522834237626 0.0185465041826777 1.2839805825242718 4.963592233009709 0.2426952123516522 0.549213451925368 1.1677027815461984 0.583872832225921 0.8314917538221126 0.2838923031197674 0.0820419193359714 0.0526645480715484 0.0047533286028597 0.0280420066437826 0.0968157430558884 +Onset 75 406 2.3505017855569386 0.0187481177095347 78.07038834951456 385.876213592233 -0.0425622816389121 0.8538092063194229 24.43720696632911 34.037910293075086 0.4423534686817674 0.2467907023311176 0.0007970917955796 0.088946285922598 0.0015317836139176 0.0081748494341408 0.0003754321934647 +Abnormal liver morphology 34 252 2.3439657228129485 0.0190799248049429 50.478155339805824 232.4077669902913 0.150816652781058 0.692155025448528 16.969619012009748 23.204530396799623 0.9016051578320304 0.3525684214206966 0.0013044206997147 0.1433207412273837 0.0009939121169996 4.687969674833119e-05 0.002288231872061 +Pulmonary infiltrates 3 7 2.336553153738735 0.0194624307283908 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.1833015620265946 1.0 0.2223047329091382 0.0244664942800011 0.0351238878380088 +Follicular hyperkeratosis 1 7 2.331970876298917 0.0197022233260393 1.6237864077669903 6.281553398058253 0.163232926315914 0.5516766232178576 1.549104731430856 1.0986971607463736 0.8802887205766023 0.2969102369878216 0.0962276778844043 0.0017760204843955 0.0066572828402184 0.0385233102424958 0.1289341732663725 +Joint subluxation 1 6 2.3233290826817985 0.0201614806244032 1.6699029126213591 5.793689320388349 0.2695740909695381 0.3801129103013786 1.1353828276538809 0.5818108495406625 1.1875606012533018 0.2916267685633827 1.0 0.0711332726649859 0.1349531130589082 0.050241067872642 0.1630814235328921 +Hypoplasia of the iris 3 6 2.3186606231283564 0.0204134452023134 1.6868932038834952 5.686893203883495 0.3781101327227986 0.4717125677764269 1.075554974493492 1.2719998237819792 0.9340346819562464 0.2867992598820882 0.0196696377913277 0.1287528218161406 0.0293903981750984 0.1476943407876319 0.0446088038944012 +Abnormality of the vasculature of the eye 18 76 2.317422390424899 0.0204807338214563 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 6.306078789685832e-05 0.0008173440708398 6.433615978694506e-05 4.026675692673187e-05 0.0016247378754383 +Flat forehead 2 5 2.313913341518897 0.020672476137282 1.1407766990291262 3.9199029126213594 0.5557307791368767 0.4398375704265163 1.0046432872431368 1.0244069988592936 1.016508733067091 0.3014269900228622 1.0 1.0 0.1008375048293403 0.0280420066437826 0.0140126286640228 +Abnormal immune system morphology 29 164 2.312868146039778 0.0207298896498953 32.53398058252427 154.25728155339806 -0.3921438711082248 0.6441708455260222 12.83753260475952 15.026411065296063 0.7341606916852351 0.3240221583309899 0.090165850606426 0.3139745775617462 0.0908732427478486 0.0018491685394954 0.0069058501836897 +Narrow nasal bridge 1 5 2.3112659555107755 0.0208181692579021 1.4514563106796117 3.424757281553398 -0.2995610077230459 0.5477964372939447 0.9779475314682458 1.2273852107838283 1.0469508992144696 0.329000309097551 0.1704659530663174 1.0 0.2070995190727305 0.1147066696002357 0.32624452618512 +Abnormality of lysosomal metabolism 2 6 2.308262076823192 0.0209845643445243 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 3.636875032407537e-05 0.0432957136582515 6.936272072908627e-05 0.0010713621736615 0.0005688349419973 +Progressive psychomotor deterioration 2 8 2.3079852756842394 0.0209999554618685 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0037203118650809 0.0573151884822011 0.0056684159955205 0.0026581093268102 0.018020673376298 +Reduced visual acuity 39 126 2.3068902187817204 0.0210609409533555 25.553398058252423 114.88106796116504 0.4786956822479749 0.5063280215354549 8.433035081523723 11.838637206126975 1.2158495541746812 0.3830713742278179 0.0495986754757388 0.2363358279753865 0.1122092796882407 0.214206394124628 0.072372499510893 +Abnormality of cardiovascular system electrophysiology 32 126 2.302118977506856 0.0213284634841752 24.868932038834952 109.79368932038837 0.0409575356563363 0.6300490557072299 9.5689782872259 12.655389848367289 0.9198174077596424 0.3314260799803207 0.2307598932956671 0.0691620079758896 0.0845166490344138 0.0046252662786457 0.0007539946396408 +Calvarial hyperostosis 1 5 2.2982888997233357 0.0215453518073822 1.7257281553398058 4.740291262135922 0.5411603752143687 0.5066705675381419 1.1448568842103286 0.6216388554640699 0.7755903575424321 0.2995402768142525 1.0 1.0 1.0 0.014977467250991 0.0542215392640632 +Atrophic scars 3 8 2.297386271392176 0.0215967442372686 1.885922330097087 6.512135922330097 0.5685434576691318 0.3662510848055916 1.2401440073700836 1.3264846238284391 1.0819526112515987 0.274421474936134 0.1704659530663174 0.1114073342812727 0.0015052123544451 0.0197332243190265 0.0269295467729808 +Abnormal facial shape 66 316 2.288616882586882 0.0221016221110326 57.09466019417476 297.5752427184466 -0.1123012576540042 0.8560428255141433 19.23988249139246 30.744589368318525 0.4077092511078453 0.2342710966759866 0.0764416661385029 0.637748276443901 0.0416132911757745 0.013958771385445 0.0303810262360261 +Talipes valgus 1 5 2.286965201825474 0.0221978542988048 1.5339805825242718 4.555825242718447 -0.1097994172329124 0.5191585232047969 1.145404782654506 0.8642242430500469 0.9649232754437164 0.3132296753281762 1.0 1.0 1.0 0.0233125205204954 0.0817606313480972 +Abnormal upper limb bone morphology 36 109 2.285923773003069 0.0222587184017513 20.936893203883496 96.55339805825244 0.1278432517404897 0.7323439366931616 7.732851246860392 12.618931805406936 0.655116563998881 0.3002568350269601 0.2870932009768402 0.8263641920843126 0.2464649134105994 0.0052135440943098 0.0340313282657353 +Obsessive compulsive trait 0 5 2.282552889319817 0.0224567186881206 1.058252427184466 4.718446601941747 0.3404953128582698 0.3777736884452908 1.1066896559256998 0.5731445492483667 1.1547313079382495 0.2847027325793588 0.0891620654695603 0.0573151884822011 0.1094892401774078 0.2559514735144251 0.4498304155532511 +Abnormality of coordination 69 332 2.277516460345423 0.0227554028196477 65.05339805825243 312.07766990291265 0.3537206479527984 0.7134221988982268 20.398983010696288 29.808593053234937 0.9921840157004412 0.3756105558441653 0.0206367734798803 0.0965949501923778 0.02152059680069 0.000538104568917 9.443056188772414e-05 +Pediatric onset 36 234 2.277084501508873 0.0227811800159702 44.25242718446602 226.19417475728156 -0.046812414602617 0.8422400589989213 15.837903685080985 18.112677667317428 0.449937136668817 0.2479606985688497 0.0075369551588075 0.0141177275620928 0.0125771984858315 0.0187941636587 0.0059915099710761 +Abnormality of lower limb joint 48 176 2.275644225419971 0.0228673120806151 33.80582524271845 166.25242718446603 0.2412979108610408 0.7714482514929651 11.09824463722585 17.08912584844864 0.6310491383229854 0.3006235946777967 0.5222531751120815 0.694945036572121 0.5018399948487189 0.0828729869383507 0.0194332256959415 +Mucosal telangiectasiae 3 11 2.271611208106699 0.0231100033316398 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0196696377913277 0.0082126449787597 0.0023694947377154 0.0044180066438726 0.0446088038944012 +Functional abnormality of the inner ear 61 259 2.254792606024961 0.024146349610254 50.34708737864078 242.22087378640776 0.1935297291549575 0.7944300178060495 15.81548387978023 20.65122416300477 0.6774851275041758 0.3153094731961924 0.0637474553632451 0.2127664180287648 0.1728991350124111 0.0453909815258638 0.0013463873937933 +Abnormality of the nasolabial region 2 7 2.253912577395948 0.0242016682775183 1.5266990291262137 5.638349514563107 0.743066342339544 0.3991951448631737 1.1498272460784271 0.9413815473257352 0.929048391056294 0.304023166451437 1.0 1.0 0.0921025797166938 0.0233125205204954 0.0105668672564949 +Prominent nasolabial fold 2 7 2.253912577395948 0.0242016682775183 1.5072815533980584 5.601941747572815 0.745829942513298 0.3983781018632273 1.1180102767775038 0.906715033484314 0.9254146185195612 0.3028058900170545 1.0 1.0 0.0832836732680532 0.0189506401306209 0.0076703518288617 +Recurrent sinopulmonary infections 3 6 2.2460888031757973 0.0246983203916471 1.9029126213592231 6.769417475728155 0.225393755188534 0.5067941660863916 1.6938756795018022 1.0486869508388323 0.9269734110569616 0.2904667225933153 0.2021881519424126 0.1330370821365251 0.2445730022705269 0.1562190614045352 0.0498364179528963 +Hernia 43 141 2.2235328595579684 0.0261798901892864 26.893203883495147 131.37864077669903 -0.0956418291849011 0.8062492250204384 11.10642481896863 14.593100181585598 0.4801821825171012 0.2498509863977245 0.5904875725163409 0.3017784745247243 0.3247156162514425 0.2465774977188663 0.0653200972741854 +Abnormal location of ears 52 254 2.2181298432156167 0.0265459805327634 44.41504854368932 237.9538834951456 0.0573706016617153 0.8767599664892582 15.161911487312535 25.154480182821903 0.4422303529904745 0.2317200782883387 0.379255966158284 0.6177410962040875 0.4220205614485135 0.2179246100516708 0.0123768977905097 +Abnormal renal vascular morphology 2 5 2.216912193315121 0.0266290923689753 1.3203883495145632 3.8737864077669903 0.1354967715812174 0.5099409340684035 1.1402911588075026 1.4476603933839365 1.0692559781762163 0.3262278930348921 1.0 1.0 1.0 0.0698282842903305 0.0539281835546241 +Ineffective esophageal peristalsis 1 6 2.2150921628297 0.0267537392628223 1.805825242718447 5.660194174757281 -0.1574364366119968 0.539146495681827 1.4865628070043426 0.6201064433878389 0.8951206901975091 0.2963468527385953 0.0962276778844043 0.0619434524836269 0.1180585699575878 0.0385233102424958 0.1289341732663725 +Weak voice 3 6 2.212183124444681 0.0269540143920967 1.550970873786408 5.737864077669903 0.4344739918343515 0.5015398770888346 1.4038172747545303 1.1779624093475138 0.8128091354527174 0.2801301484192541 1.0 1.0 1.0 0.373917962138579 0.0118865434534573 +Abnormal urine metabolite level 36 172 2.209958852144004 0.0271080181611669 34.70145631067961 155.20873786407768 -0.3573924228710131 0.6645772685580115 14.249193396198468 12.347914464025754 0.8147083523893842 0.3308460466966603 0.0215165124065431 0.0311514606714673 0.0077847683850857 0.0012931081018157 0.000336759103936 +Beaking of vertebral bodies 3 9 2.2092591180549475 0.0271566230045068 2.907766990291262 9.131067961165048 0.3586161575708288 0.4129848752927794 1.656478269216378 1.797329687366794 1.1037549452259698 0.2913355105961067 0.14419427418718 0.0937235599037543 0.1758008751515455 0.0012174977382918 0.0143001062154138 +Meningitis 4 7 2.2058911361814277 0.0273916230013011 2.179611650485437 6.274271844660194 0.789971069936712 0.3622376484019577 1.3480557177345056 1.3864875660317604 0.9776190102947984 0.2839276823170232 0.2083873391143312 0.1373006943976843 0.2518545844225215 0.1648346062433529 0.0137665493817408 +Abnormal bleeding 28 105 2.20354499449022 0.0275563593127847 21.04368932038835 103.1480582524272 0.3205179723276434 0.6638707666517285 7.482862879563674 10.194702656234456 0.7473134672907507 0.3396929867916743 0.455350241590528 0.2079001035716013 0.3722243941480677 0.0925019200504019 0.1007696253812064 +Enlarged ovaries 2 5 2.20294378401214 0.0275987111106337 1.5485436893203883 3.9927184466019416 0.8804191551340563 0.3864999840666678 1.06582973536596 0.6879301925732709 0.9100376378468832 0.3059866077722108 1.0 1.0 1.0 0.0331187861076589 0.1125747569923622 +Movement abnormality of the tongue 1 5 2.2025329930435347 0.0276276812309008 1.3446601941747574 4.189320388349515 0.1948937934972384 0.5006787756698039 1.0895111717049373 0.7227795083838882 0.973210749807661 0.309363274056201 0.0676363609296167 1.0 0.0832836732680532 0.0189506401306209 0.0675218785318175 +Abnormal urine carbohydrate level 5 13 2.2014853346771983 0.027701683774822 3.883495145631068 11.70631067961165 -0.1388020161424021 0.4168246977061866 1.9096127339504616 1.3287920569685254 1.2303643442685093 0.3136870898203888 0.0210218377513724 0.1330370821365251 0.0026246094830452 5.7864269479668425e-05 0.0023211498250519 +Corneal dystrophy 0 5 2.19992497983318 0.0278122180859969 1.699029126213592 4.696601941747573 0.2921039737779333 0.4118294649560281 1.1644820629274713 0.7585679576702383 1.1195166232896612 0.2961332092572092 0.1101969479300293 0.0711332726649859 0.1349531130589082 0.3090006421698555 0.5262254411875915 +Pulmonary embolism 3 6 2.1880924382769926 0.0286628696154063 1.1019417475728157 3.70873786407767 0.7551393623016334 0.4292109064890334 0.9947903699281576 1.111555089814502 0.8897716408439532 0.3033269362757949 1.0 1.0 1.0 0.0768284795296569 0.0118865434534573 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5.575242718446602 0.7192357902216235 0.3771156375814327 1.260629702441343 1.0104640332277932 0.9717173289058264 0.2836036003591781 0.0603501083335805 1.0 0.0743799864466655 0.014977467250991 0.0053031795330487 +Cerebral dysmyelination 0 7 2.165692969534429 0.0303346566366531 1.6286407766990292 7.055825242718447 0.5887869749232204 0.3891898742700928 1.2754040277752834 0.7202278823189237 0.9907764921844316 0.2830027899418403 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.3258327648280404 0.5492603500015365 +Pneumothorax 1 6 2.165350611397584 0.030360845224193 1.8422330097087376 6.577669902912621 0.4169163529904772 0.4794672100341537 1.4268108453557962 1.3886804548199774 0.9001924924499753 0.2912387954099875 1.0 1.0 0.2518545844225215 0.1648346062433529 0.4315495391205481 +Pain 44 188 2.150288613026067 0.0315323925496648 37.08009708737864 174.89563106796118 0.560521494187844 0.6082034136674831 12.418311408681989 15.731400802334642 0.9626712538875356 0.3834317739449847 0.1707666301583339 0.0865676063800509 0.182214292423097 0.0473632814153301 0.0292050696893469 +Involuntary movements 75 352 2.146592722299126 0.0318257198117506 64.20631067961165 324.16747572815535 0.1561786112826782 0.7846530873453128 17.968922983446493 30.75077724863295 0.6578098650819268 0.313999179195925 0.0108386893523913 0.0181963959412561 0.0125122027305397 0.0033353270753338 3.730367166295928e-05 +Pulmonary cyst 1 5 2.1406126514254904 0.0323052876988394 1.895631067961165 5.274271844660194 -0.4127730987100335 0.4961080912703863 1.2833059324714178 0.7632443550514845 0.8978811341950451 0.3008387411511471 1.0 1.0 1.0 0.0565188023636715 0.1807018090276839 +Abnormality of pelvic girdle bone morphology 40 156 2.1360177248872043 0.0326779691049186 28.953883495145632 143.15533980582524 0.1528429479212115 0.8094616238277529 9.960373402464574 15.115899994757912 0.5373878280379736 0.2768166775581852 0.8602805077717364 0.6408117354005051 0.6142152481228315 0.069501299884982 0.013848122937046 +Capillary hemangioma 3 9 2.1255306760147747 0.0335423572045627 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.2267009545659739 1.0 0.2732850813359189 0.0453869127531283 0.07392944267488 +Sparse body hair 2 10 2.11932972981364 0.034062610839306 3.342233009708738 10.08252427184466 -0.3030063928435675 0.4907312013716142 2.1342930127217956 1.1418709893008905 0.9575476201653794 0.2935588277766331 0.0170809326588952 0.1201219647894398 0.0019068669696529 0.0244664942800011 0.1298078118605267 +Depression 26 106 2.1133141041723023 0.0345738923300928 21.866504854368937 102.23058252427184 0.3844987984674038 0.6518312597777748 6.663852964137664 9.29780935941184 0.7952008671962957 0.3502437860603438 0.1410418979228345 0.3639982677015973 0.2381777748598305 0.0107062566256306 0.0075839987543255 +Abnormal conjunctiva morphology 9 27 2.113253012216632 0.0345791181157331 6.997572815533981 26.58495145631068 0.5265054436970301 0.4429378103171669 2.669041123051977 2.4927208099742058 1.133049116684961 0.3300379664677785 0.0008263275180717 0.0111951113174208 0.0002948437912435 0.0004899397835102 0.0166301029449077 +Hepatomegaly 25 184 2.1090243411430456 0.0349424806389937 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 0.0028769295943545 0.1199184951243544 0.001155404431858 6.529012172817231e-05 0.0021172983449188 +Abnormal peristalsis 1 7 2.1071393700633005 0.035105500552113 2.1966019417475726 6.691747572815534 -0.2400737592613135 0.5551921581764555 1.7509187898186251 0.6344708477691202 0.8378954659079706 0.2950570786595453 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.0565188023636715 0.1807018090276839 +Macrogyria 1 6 2.1016106947785227 0.0355873922474512 1.5024271844660195 5.648058252427185 0.9880312678764684 0.314713035809367 1.057793055191099 0.9137148736849272 0.850980571286911 0.2493075505833739 0.0123851923729949 0.1026081339138497 0.018640880521655 0.0990342687178565 0.2898287915273368 +Limb joint contracture 11 105 2.1015301288317265 0.0355944560648562 21.16747572815534 100.42233009708738 0.6687590042181877 0.5853612155895958 7.458858708924721 11.434332835202127 0.8235264349573469 0.3682957054317731 0.3889108928658217 0.1682346394206446 0.1452044714497424 0.1670471697214935 0.43282063382683 +Neurofibromas 2 7 2.0994191541343907 0.0357799676776584 1.8980582524271843 5.745145631067961 0.0175409624359088 0.5410026201994014 1.4191123016738296 1.3779120014158963 0.8845933131565403 0.2919059257788376 1.0 0.0847528009868792 0.1596960736798767 0.0088528623379573 0.0539281835546241 +Coarse facial features 22 74 2.096747234344539 0.0360159567805518 14.893203883495143 65.1116504854369 -0.0571685725971772 0.580093215118004 6.012789962503995 6.952485076014798 1.0405087875423698 0.3452061173820699 0.000412808436672 0.0549135737484113 0.0002821358453052 1.2665525179270952e-06 4.145867094285355e-06 +Abnormal inflammatory response 40 252 2.094947187432362 0.0361756874922696 44.85679611650485 237.17233009708735 -0.0584148051359406 0.8569822858557721 15.434841982238884 21.766566314734956 0.4018934138512305 0.2329208395193305 0.6027037058567484 0.6491691036218417 0.4697757164880188 0.0606188697248105 0.0252568268783395 +Exaggerated startle response 4 9 2.0889251491159717 0.0367144615820327 2.987864077669903 8.699029126213592 0.0610274034602423 0.2634753902852135 1.4337635656228835 1.0620090089420118 1.617556501702403 0.2831541938798349 0.000190495704273 0.0023758658868836 0.0003602808960722 0.0003774704498572 0.0005289198821125 +Myoclonus 16 110 2.0859499935598667 0.0369831530287094 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 0.0007920920720502 0.0080948593790297 0.0031782304928799 0.0005137742866614 0.0015111999514974 +Abnormal tendon morphology 22 217 2.0855140279117874 0.0370226661623953 39.83009708737864 210.66747572815535 0.186427012418248 0.8250793001687675 13.057574783009096 21.97689895783318 0.5249130695927144 0.2801943200265986 0.0675259956208867 0.2942643036739734 0.0072354258848652 0.0095685159277323 0.2466651005399141 +Abnormality of the knee 20 97 2.079661551842347 0.037556586992163 18.313106796116504 87.3131067961165 0.3621304338986751 0.6629253310601161 6.232667076902729 10.461511662764035 0.6968901749422698 0.325188898669675 0.3272755240308372 0.7260205862589838 0.2402570181343245 0.0110327591054599 0.0152611048900872 +Disproportionate short trunk short stature 1 6 2.078959905834091 0.0376210357964792 1.5218446601941749 4.983009708737864 0.4124275912660306 0.360786721341216 0.9306060741204804 1.0713400871945435 1.1869525657580595 0.284085703465065 1.0 0.0937235599037543 0.1758008751515455 0.0840389641709933 0.2531867173469597 +Dysphagia 37 142 2.072681245860059 0.0382019542594278 26.58252427184466 132.13349514563106 0.525484494447878 0.6234130914808526 8.355016250174085 12.686440449515484 0.9112834521434876 0.3703513369566691 0.1452956194951403 0.0984467873143219 0.0219996752028997 0.002926267606953 0.0267806917971377 +Hypertonia 79 396 2.0717233403419244 0.0382912493715186 70.76941747572816 367.55582524271847 -0.0144063616310395 0.8039103144210004 21.33693494540743 35.003873434049204 0.6301020293448386 0.3002424721386536 0.0002836341364968 0.0027180265768209 0.0005222513727729 0.0010344453375309 4.505796918860891e-05 +Abnormality of metacarpophalangeal joint 0 5 2.070651707505045 0.0383913562805464 1.4514563106796117 4.206310679611651 -0.0844519287039477 0.657631691586024 1.0144934244663284 0.7527676962045149 0.67872466106937 0.2695907638592831 0.0891620654695603 1.0 0.1094892401774078 0.2559514735144251 0.4498304155532511 +Abnormality of the pulmonary veins 0 6 2.06273756517908 0.0391375687940331 1.2135922330097086 6.669902912621359 0.9535622979003926 0.3793496965363341 1.175399006302687 0.7806936113776552 0.7920022166500139 0.2937792263138297 0.2386769792225308 0.1583124314184509 0.2872333566147377 0.5782306803788487 0.8253222698749051 +Aortic dissection 2 5 2.0609670280579517 0.039306185792757 1.3883495145631068 3.924757281553398 0.165303372009239 0.6117931827880814 1.1802008197450755 0.8135196749164123 0.8096483599737048 0.3115713337494391 1.0 1.0 1.0 0.4185863086244521 0.2898287915273368 +Abnormal tissue metabolite concentration 4 16 2.0527048696556243 0.0401012094851365 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 4.9205512370228445e-06 1.8856680763096997e-05 1.4194050004739812e-05 0.0011115841037105 0.0045924061823516 +Limitation of joint mobility 24 105 2.052428558853131 0.0401280314175771 21.060679611650485 97.9368932038835 0.3085934150476662 0.6495028096480517 7.742751544501191 10.216391648179064 0.8329388631334591 0.334643383369233 0.3485961132117078 1.0 0.4830548732924943 0.0323102740635971 0.0120250060873721 +Avascular necrosis of the capital femoral epiphysis 1 5 2.045122252968537 0.0408428069133537 1.3883495145631068 3.104368932038835 -0.4391824425102574 0.5376239004472406 0.8728149940061183 0.9091126260270352 0.9481428606263754 0.3137204843436084 1.0 1.0 1.0 0.373917962138579 0.2348875720984273 +Widow s peak 0 6 2.0240019433076983 0.0429699517971939 1.4733009708737863 3.5145631067961167 0.1557809141300458 0.5995685016105755 1.1392237932750993 0.8602785467837537 0.8690320794979043 0.312795287230818 0.0891620654695603 0.0573151884822011 0.1094892401774078 0.2559514735144251 0.4498304155532511 +Abnormal morphology of the abdominal musculature 3 10 2.022350016707555 0.043140204870776 2.5194174757281553 9.696601941747574 0.2129739773830804 0.6038296710628059 1.594015400665463 1.8242402612786552 0.6929182513306914 0.2584919547665449 1.0 1.0 0.0588586045542952 0.0771340965144245 0.1361773244383703 +Restrictive ventilatory defect 2 12 2.006844688636646 0.0447662028207547 3.133495145631068 11.29368932038835 -0.1840018037273681 0.550417830011822 2.2628584932903 2.067703331845921 0.90055543561596 0.3056517214970243 1.0 0.1828652209005429 0.327507803675052 0.0771340965144245 0.3205947305401093 +Clumsiness 5 19 2.0013242836787417 0.0453574544303496 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0005428611587635 0.0017444833819082 0.0012207780133745 0.0011347755104788 0.0089113675821019 +Aplasia hypoplasia affecting the eye 29 105 1.998196365436794 0.0456953754356195 19.941747572815533 95.95873786407768 0.0764255407900039 0.7981739483266604 6.943706017442621 12.372093023642108 0.5013616923456197 0.2575781415659169 0.4875027574847694 0.8144920448302877 0.6337000020231498 0.5788991650806251 0.4711962085994706 +Abnormal intraocular pressure 2 6 1.9979851671232025 0.045718268245098 1.7378640776699028 5.364077669902913 0.7975593383695336 0.3664160137723464 1.328998199598039 1.2081723635255046 0.9260288950993424 0.2857643490638551 1.0 1.0 0.1677870330809631 0.0768284795296569 0.2348875720984273 +Progressive spastic quadriplegia 2 9 1.994953967701963 0.0460479006445266 2.6407766990291264 8.094660194174757 0.8041722661618813 0.2980182786117089 1.3079619433616207 1.0302561803519357 1.23715789109981 0.2930725496255146 0.0025621931302305 0.0010343090391069 0.0039135152062846 0.0015031185668187 0.0105668672564949 +Macular degeneration 4 12 1.9942804585252631 0.046121413582044 3.5072815533980584 13.201456310679612 0.7081764422831481 0.3007939344006393 1.5711122114355351 1.3240485924903622 1.388921785741595 0.3097317018961461 0.0612866879874208 1.0 0.0890100643743446 0.0372180748890915 0.106558868417216 +Infantile axial hypotonia 3 10 1.993322668312106 0.0462261257358929 3.0970873786407767 9.91747572815534 0.2141703344813526 0.3664899290512883 1.6385203075306134 1.5973234399272347 1.21609252960959 0.2741067096589152 0.0224117239029505 0.0093923264669034 0.0334071197556988 0.0356014336373073 0.0553856285019619 +Macular atrophy 1 6 1.9878919636464627 0.0468236397402743 1.703883495145631 6.686893203883495 0.2113778572915335 0.58323379585624 1.5871707948603664 0.7673704047649692 0.7676229149902041 0.2797351797627675 1.0 1.0 1.0 0.0990342687178565 0.2898287915273368 +Orthostatic hypotension due to autonomic dysfunction 1 8 1.9878408576894675 0.0468292934011618 2.8689320388349513 9.026699029126211 0.6690910568198125 0.3153802844238013 1.4405048418053912 0.8105887688186777 1.185865447592776 0.2910194211316744 0.1032391689436505 0.066549445548378 0.1265462710440741 0.0442367692127036 0.1457988469723397 +Deviation of the 2nd finger 1 5 1.98767708662456 0.0468474146513262 1.2621359223300972 4.002427184466019 0.1765561340307891 0.5038922294894571 1.0307049623384947 1.1093135864341577 0.9478551661778964 0.284871094520323 1.0 1.0 1.0 0.0331187861076589 0.1125747569923622 +Thyroid adenoma 1 6 1.9871588324160745 0.0469047983047556 1.864077669902913 4.689320388349515 -0.112518602266888 0.634648079190412 1.4007525279123445 0.8733278192497805 0.7476906942090116 0.2902286031945779 1.0 1.0 1.0 0.0331187861076589 0.1125747569923622 +Primitive reflex 1 7 1.9860842390911304 0.0470239710156037 1.6577669902912622 6.473300970873787 0.1438683145583185 0.5404266379823655 1.48352206997882 0.6511869496520302 0.8727162108456575 0.2923205410359579 0.1032391689436505 0.066549445548378 0.1265462710440741 0.0442367692127036 0.0277461310389573 +Arterial thrombosis 3 7 1.9829609746573205 0.0473717888504892 1.672330097087379 6.116504854368932 0.4885409007378155 0.4989080224824349 1.3766116442887053 1.0125520087209272 0.8560909896754757 0.3058070527847597 1.0 1.0 1.0 0.0565188023636715 0.0062633876942655 +Macroorchidism 2 7 1.9797046925614383 0.0477367209849552 1.769417475728155 4.779126213592233 0.0374066307417017 0.5141640167272787 1.2474193362583803 1.020304168236421 0.9783164314295948 0.3058016686148713 1.0 1.0 1.0 0.0020298329670106 0.0140126286640228 +Abnormal eyebrow morphology 38 165 1.978757942303757 0.0478432658102425 34.140776699029125 156.38349514563106 -0.2512156581009782 0.7392429143601362 13.357285469918429 17.042879087460026 0.5659182605306375 0.2894441034901881 0.1541704470729366 0.1958148713339325 0.0806064082499579 0.3512634659197264 0.1999003050408581 +Overgrowth 2 5 1.968465839586224 0.0490144628679589 1.9271844660194175 4.815533980582524 -0.1347801047320733 0.5606055907044043 1.4909236190418838 1.6100266705596158 0.9001393564494012 0.3052094893374437 1.0 1.0 1.0 0.3891747515056749 0.0701952648708137 +Foam cells 5 7 1.9678061541966492 0.0490903458229485 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 0.0603501083335805 1.0 0.002465796513642 5.243287226084708e-09 3.274702614006158e-07 +Psychomotor deterioration 2 10 1.966744277090112 0.0492126995646506 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 0.0001210863842979 0.0017760204843955 0.0002296483500821 0.0033939033653995 0.0027630263410089 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6629a03651d05e9652752dff4ea55a528bd534e5 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 4637, + "title": "Average number of proteins per term", + "value": 24.886564589174036 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d17fb3e68a078a9c9f2e69ff46f54d9d66c933f5 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fa7201c18e1d1eb5c1ecd4a54c885740bbfef943 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1805 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Abnormality of the spleen 0.5556387402002416 3.987905025681654 6.665933766480947e-05 0.2658997295010594 0.1766109446917272 126 P07602,O15118,P04062,Q15392,P16278,P38571,P04066,P28070,P08236,Q14108,P54802,P15586,Q15904,P10253,P10619,Q13510,P07686,P61916,Q99519,P35670,O00754,P31749 22 +Mental deterioration 0.5222602144246447 3.541090768433829 0.0003984764695419 0.8424643704017978 0.1766109446917272 106 Q9NQ11,P07602,P35670,P06865,P17900,P05067,Q14108,P07686,O75503,Q13510,P61916,P54802,P04062,Q9NWW5,P50897,Q9Y287,O15118 17 +Cognitive impairment 0.4773361669016384 3.442716469002832 0.0005759027553065 0.9308329257109816 0.1766109446917272 177 Q10713,Q04446,P07602,P56589,O60313,O15118,P17900,P05067,P04062,P16278,O75503,P60866,Q9Y287,Q9NZ08,P21359,P17480,P06280,P06865,Q14108,O43464,P54802,P01889,P50897,Q8NC96,Q13144,P13473,Q9Y263,Q9Y487,Q9BQE5,Q9Y4U1,Q13510,P40855,P07686,Q5XKP0,P00403,P61916,Q9NWW5,Q99720,Q14203,Q9NQ11,P35670,Q96RR1,P54098,P10644,P31749,Q9GZZ9,Q9NUM4,O60934,P35270,Q9H9S5,O95831,Q99643 52 +Splenomegaly 0.6331213104080472 3.437505083944127 0.0005870996980974 0.9343344449760156 0.1766109446917272 94 P07602,O15118,P04062,Q15392,P16278,P38571,P04066,P28070,P08236,Q14108,P54802,P15586,Q15904,P10253,Q13510,P61916,Q99519,P35670,O00754,P31749 20 +Abnormality of the lymphatic system 0.4921281196827888 3.4036601940601954 0.0006648941240614 0.954230597556586 0.1766109446917272 153 Q9BZK7,P07602,O15118,P04062,O15460,Q15392,P16278,P38571,P21359,P04066,P28070,P08236,Q14108,P54802,P01889,P15586,Q15904,P10253,P10619,P31751,Q13510,P07686,P61916,Q99519,P35670,P10644,O00754,P31749,P40763 29 +Abnormal joint morphology 0.4293036195848659 3.3214841453497623 0.0008954006938772 0.9842958923583118 0.1766109446917272 283 P10321,O15111,Q8TD16,P07602,P34059,P04062,Q04656,O15460,Q15392,P16278,Q8IWS0,P42892,O75787,Q9H173,Q9NZ08,P07384,P21359,Q8IZA0,P06280,P28070,Q93074,P08236,Q14108,O43909,Q92917,Q9NQX3,P01889,Q8NCH0,Q7LGA3,Q9UBM7,P23229,Q8TAA9,P62258,Q9Y487,Q13510,Q9NX62,Q5JRA6,O96028,Q15125,Q8WVQ1,P35670,Q93063,O00754,P10644,P31749,Q15041,P51798,Q15056,P40763,O95831 50 +Abnormality of the cervical spine 0.4972583346852903 3.2682014250901075 0.0010823330787432 0.9934053491936174 0.1766109446917272 116 Q8TD19,Q9BZK7,P34059,Q8N6M0,P16278,P60866,O00192,Q96EK5,P21359,P04066,Q96HY6,P62857,Q9C0B1,Q93074,P08236,O43909,Q92917,P15586,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P62258,Q9ULC3,Q15427,Q15125,Q8WVQ1,O00754,O60934,Q9H9S5,O95831 31 +Visual impairment 0.4234375178613891 3.232026265718322 0.0012291575738374 0.9966644223239792 0.1766109446917272 297 Q13277,Q10713,P07602,P56589,O60313,P17900,O15460,Q96N67,P16278,O75503,P98164,Q8IWS0,O14773,P60866,Q9Y287,Q9NZ08,P21359,P49591,Q9Y6B6,P15311,Q5KU26,Q5JPH6,Q9H490,O43395,P06865,Q9H3S7,P51797,P01889,P50897,Q07021,Q8N183,Q7LGA3,Q15555,O43292,Q13144,P13473,Q5XKP0,Q9Y4U1,P40855,P07686,P00403,Q6P4A7,O43567,Q9NWW5,Q7Z3E5,O43505,O43709,P48449,P04439,Q96PZ0,P39880,Q99519,Q9UBB6,Q9BV79,Q01105,Q96RR1,P54098,O96000,Q96N66,P31749,P51798,Q15056,P29992,Q9UN37,Q9H9S5,O95831 66 +Abnormal retinal morphology 0.4367672609258837 3.231136159735931 0.0012329918893281 0.9967232756667694 0.1766109446917272 235 Q10713,P07602,P56589,Q7KZN9,O60313,P17900,P04062,P16278,O75503,P98164,P51648,O14773,Q9Y287,O00192,Q9NZ08,P21359,Q9Y6B6,O43395,P06865,Q9H3S7,P01889,P50897,Q8N183,Q8NCH0,Q7LGA3,Q8NC96,Q15555,P04114,P10619,Q9Y467,Q9Y487,Q5XKP0,Q9Y4U1,Q7LG56,Q13510,P07686,P40855,P00403,O60333,Q9NWW5,Q7Z3E5,Q5JRA6,O43505,O96028,O43709,Q96PZ0,P04439,Q8N3R9,Q9UHX1,Q99519,Q8NCM8,O75489,P54098,O00754,P31749,Q9GZZ9,Q15056,P40763,P29992,Q9UN37,Q9H9S5,Q99643 62 +Kyphosis 0.4757608925315614 3.210012832185919 0.0013272904678973 0.9978850709621122 0.1766109446917272 156 Q8TD16,P34059,P04062,Q04656,P16278,Q8IWS0,Q96ST3,P51648,Q14739,Q9H173,P21359,P17480,P04066,Q5KU26,O43909,P08236,Q14108,Q9H3S7,Q13620,P01889,Q8NCH0,Q7LGA3,Q9UBM7,Q9Y263,Q9Y487,Q32P28,O96028,Q9ULC3,O43709,Q15125,Q96PZ0,Q8N3R9,Q9UHX1,Q9HC07,Q99519,Q8WVQ1,Q9BQP7,P10644,O00754,P31749,Q15056,O75844,Q9H9S5,O95831,Q99643 45 +Abnormal cornea morphology 0.4661951265652678 3.112100394865849 0.0018576131442575 0.9998198575410084 0.1766109446917272 160 O15111,Q9BZK7,P56589,P34059,P04062,P16278,P51648,Q14739,O00192,Q9NZ08,Q96EK5,P04066,P06280,O43395,P08236,Q9H3S7,P01889,Q8ND04,Q07021,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P04114,P10619,Q13510,P40855,O43505,O96028,Q9ULC3,Q15125,Q96PZ0,O43709,Q99519,P35670,O00754,P31749,Q15056,Q10471,O75844,Q9H9S5 41 +Thickened skin 0.4832177047796466 3.091548777430144 0.0019911526565024 0.9999031337328236 0.1766109446917272 107 Q8TD19,P56589,P04062,Q04656,P16278,P51648,Q14739,Q07954,P21359,Q14574,P04066,P06280,P28070,Q13620,Q14126,P53634,Q15555,P31751,P40855,Q15125,P48449,Q99519,P09493,P31749,O75844,Q99643 26 +Abnormal systemic arterial morphology 0.4643326120524547 3.022692227225994 0.0025053690635761 0.9999911223496238 0.1766109446917272 151 P07602,O15118,P17900,P05067,P04062,P16278,Q04656,O15460,P38571,P21359,P62857,Q93074,P06865,P01889,P10253,Q7LGA3,Q9UBM7,P04114,P10619,Q13510,P07686,P61916,Q96PZ0,Q99519,P10644,Q15056 26 +Vascular skin abnormality 0.4723574657587268 2.987662313986738 0.0028111997491382 0.9999978582566104 0.1766109446917272 124 P07858,Q9BZK7,P04062,Q04656,P16278,P51648,Q14739,O00192,Q07954,P21359,Q8IZA0,P04066,P06280,Q9C0B1,Q14108,P01889,Q9NX24,Q8NCH0,Q9UBM7,P10619,Q9Y487,P00403,Q15427,Q15125,O00462,Q99519,Q99829,P35670,P10644,P31749,P51798,P40763,Q13126,O75844,Q99643 35 +Abnormal vascular morphology 0.4180829792978134 2.9505603284595487 0.0031719809194172 0.9999996000204724 0.1766109446917272 240 Q8TD19,O15111,Q69YQ0,P07602,O15118,P17900,P05067,Q9UBS4,Q15392,P04062,P16278,P42892,Q04656,O15460,P60866,Q9H9B1,O00192,P38571,Q9NZ08,Q9Y3D3,Q9UQR1,P21359,P62857,Q9C0B1,Q9Y4J8,Q93074,P06865,P08236,O43395,P01889,Q8ND04,P10253,Q7LGA3,Q9UBM7,P04114,P10619,Q9Y487,Q13510,P40855,P07686,P61916,O60333,Q7LBC6,Q9ULC3,Q15427,O43709,Q96PZ0,Q99519,P19022,Q93063,P10644,P31749,P51798,Q15056,P40763,O75844 56 +Cerebral amyloid angiopathy 0.9938034818530536 2.9478425303943623 0.0032000002255523 0.9999996488994752 0.1766109446917272 2 P05067 1 +Recurrent respiratory infections 0.4669586094515279 2.9466965274732786 0.0032118824753877 0.999999667780008 0.1766109446917272 131 Q13277,P07602,P34059,P04062,O15460,P16278,P02786,P04066,O43909,P08236,P54802,P01889,P15586,P53634,P10253,Q9Y487,Q13510,O96028,O00462,P51798,Q15056,O60934,P40763 23 +Abnormality of bone mineral density 0.4606567752923564 2.931731567123398 0.0033707796177597 0.99999984137257 0.1766109446917272 143 Q13277,P07602,P34059,P04062,Q04656,Q15392,P16278,P21359,Q9H490,P06280,Q14108,P54802,O43292,Q9Y487,Q32P28,Q13510,Q5JRA6,O96028,O43709,Q15125,Q8WVQ1,Q9UDY2,P35670,Q96RR1,P54098,Q93063,O00754,P10644,P51798,Q15056,P40763,P29992,Q13126,O95831 34 +Abnormality of the abdominal wall 0.4658496934143541 2.9163527870168013 0.003541498056619 0.99999992832146 0.1766109446917272 127 Q8TD19,O15111,Q69YQ0,Q10713,P34059,Q04656,P16278,Q9H9B1,P98164,Q96ST3,Q14739,Q6W2J9,O00192,P04066,Q96HY6,Q9C0B1,Q9Y4P3,P08236,Q93074,Q9BXW9,Q9NQX3,Q13620,Q8NFV4,Q8WYQ5,Q8NCH0,Q9UBM7,Q15555,P60953,P62258,Q9Y487,Q32P28,O43567,Q7LBC6,Q9ULC3,Q15427,O43709,Q9UHX1,O00462,Q99519,Q8WVQ1,Q8NCM8,O00754,P31153,P43034,Q15056,O75844 46 +Amyloidosis 0.9852479067352696 2.910360028520288 0.0036101263009125 0.9999999479179572 0.1766109446917272 3 P05067 1 +Asymmetric septal hypertrophy 0.9843611684862792 2.909587930744343 0.0036190556700452 0.9999999500379096 0.1766109446917272 2 P54802 1 +Abnormal lower limb bone morphology 0.4381011247909561 2.899428173938654 0.0037384398743836 0.9999999713361728 0.1766109446917272 180 Q8TD19,O15111,Q69YQ0,Q10713,P07602,P34059,Q9BZK7,P04062,Q04656,Q15392,P16278,Q8IWS0,Q14739,O75787,Q9H173,O00192,P08069,Q969X5,P21359,P04066,Q96HY6,P06280,O43909,P08236,Q9H3S7,Q13620,Q96MW5,Q7LGA3,Q9UBM7,Q13555,Q9Y263,Q9Y487,Q32P28,Q13510,Q9NX62,Q7Z3E5,Q5JRA6,O43505,O96028,Q9ULC3,Q15125,Q96PZ0,Q15427,Q8N3R9,Q9UHX1,Q8WVQ1,Q93063,O00754,P10644,P31749,P51798,Q10471,O75844,Q9H9S5,O95831 55 +Unusual infection 0.4211899615742522 2.881750883619183 0.003954722621194 0.9999999895263748 0.1766109446917272 214 Q13277,Q9BZK7,P07602,P34059,P04062,Q04656,O15460,P16278,Q9H9B1,Q9NZ08,P02786,P04066,P28070,O43909,P08236,Q13423,P54802,P01889,P15586,Q13472,P53634,Q15904,P10253,Q9UBM7,Q8TAA9,Q9Y487,Q13510,O96028,O00462,Q9BQP7,P10644,O00754,P31749,P51798,Q15056,O60934,P40763,Q9UN37 38 +Fingerprint intracellular accumulation of autofluorescent lipopigment storage material 0.9755089997049252 2.8735629705477197 0.0040587015863886 0.999999993545548 0.1766109446917272 2 O75503 1 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9757969303423832 2.871744336744639 0.0040821307365483 0.9999999942125885 0.1766109446917272 3 O14773,O75503 2 +Localized skin lesion 0.4147919493539604 2.841762977128388 0.0044864833159761 0.999999999119588 0.1766109446917272 229 Q8TD19,O15111,Q69YQ0,Q04446,P07602,P04062,Q04656,Q8N6M0,Q15392,O15460,Q96ST3,Q14739,O00192,Q9NZ08,Q969X5,Q07954,P21359,Q8IZA0,Q14574,P06280,O43395,Q93074,O43909,Q9H3S7,Q13620,P61586,P01889,Q13472,P53634,Q8NCH0,Q7LGA3,P23229,Q15555,P04114,Q8TAA9,P62258,Q13510,O60333,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,O43709,Q93063,P10644,P31749,Q15056,O60934,P40763,Q13126,O75844,Q92542,Q99643 54 +Increased cerebral lipofuscin 0.9622747862788092 2.8090604511012116 0.0049686315953103 0.9999999999068652 0.1766109446917272 6 O14773,P50897,P07602,O75503 4 +Sea blue histiocytosis 0.958677685950412 2.8013382169944374 0.005089115124502 0.9999999999468806 0.1766109446917272 3 P61916,O15118 2 +Cervical myelopathy 0.95867768595041 2.8013382169944236 0.0050891151245022 0.9999999999468806 0.1766109446917272 3 Q93063,P34059 2 +Vacuolated lymphocytes 0.9589607322113972 2.799680036301968 0.0051153282447706 0.9999999999529896 0.1766109446917272 4 Q99519,O00754,P04066 3 +Thickened ribs 0.9589607322114 2.799680036301968 0.0051153282447706 0.9999999999529896 0.1766109446917272 4 P54802,O00754,P15586 3 +Angiokeratoma 0.9589607322114008 2.799680036301968 0.0051153282447706 0.9999999999529896 0.1766109446917272 4 O00462,P04066,P06280 3 +Abnormality of upper limb joint 0.4564369835280721 2.7906748423761365 0.0052598283161695 0.9999999999760294 0.1766109446917272 125 P34059,Q04656,Q15392,P16278,P42892,Q9H173,Q969X5,P21359,Q8IZA0,Q93074,O43909,Q92917,Q7LGA3,Q13510,O96028,Q9ULC3,Q15427,Q15125,Q8WVQ1,Q93063,P10644,P31749,Q15056,O95831 24 +Bone marrow foam cells 0.955417773841159 2.784973535082761 0.005353209208246 0.9999999999844896 0.1766109446917272 4 P61916,O15118,Q99519 3 +Abnormality of glycolipid metabolism 0.9560502700093072 2.782106029124253 0.0054007392527506 0.9999999999875724 0.1766109446917272 7 P06865,P17900,P07602,P06280 4 +Abnormality of the upper respiratory tract 0.457130541173387 2.779351805057006 0.0054467500069801 0.9999999999899716 0.1766109446917272 107 Q13277,P07602,P34059,Q9H0U9,O15460,P16278,P21359,P04066,P28070,Q93074,P08236,P54802,P01889,P15586,Q9UBM7,Q13510,P10644,O00754,P40763 19 +Abnormal anterior eye segment morphology 0.3994759134114717 2.7638281694367777 0.0057127614237166 0.9999999999970992 0.1766109446917272 329 Q8TD19,Q10713,P34059,P56589,O60313,P98164,Q96ST3,Q14739,P60866,Q9Y287,O00192,P04066,P06280,Q9H3S7,P61586,P00390,Q9NX24,Q8NCH0,Q7LGA3,P10619,Q9Y467,Q9Y297,Q13510,Q7LG56,O43567,O43505,P48449,Q8N3R9,Q9UHX1,Q99519,Q8WVQ1,Q9BUR4,Q8NCM8,P35670,O00754,P31153,P31749,P22570,Q9NR77,P04062,P16278,Q9H1A4,Q9H173,Q6W2J9,P26358,P21359,P46783,Q9Y4P3,P08236,Q9BXW9,P50213,P01889,Q8NFV4,Q9H2M9,Q07021,Q8WYQ5,Q9UBM7,P04114,Q96PZ0,P04439,P10644,Q15056,Q10471,Q9UN37,Q9BZK7,P08069,Q9NZ08,Q96EK5,P62857,O43395,Q8ND04,P40855,P23258,O96028,Q15125,P19022,Q13126,O15111,Q9H9B1,Q8IWS0,P51648,O43464,Q15555,P00403,O60333,Q7Z3E5,Q9ULC3,O43709,Q96RR1,P54098,Q9GZZ9,P29992,O75844,Q9H9S5,Q99643 95 +Undetectable electroretinogram 0.949562366770126 2.760611829903603 0.0057693202371646 0.9999999999977718 0.1766109446917272 4 O14773 1 +Abnormal vertebral morphology 0.454162622904448 2.7501746427051854 0.0059563509840174 0.9999999999990687 0.1766109446917272 120 Q8TD19,Q10713,P34059,P04062,Q04656,P16278,Q8IWS0,P21359,P04066,O43909,P08236,Q14108,P54802,P15586,Q8NCH0,Q9UBM7,Q8TAA9,P10619,Q32P28,Q7Z3E5,Q5JRA6,O96028,Q15427,O43709,Q15125,Q99519,Q8WVQ1,P10644,O00754,P31749,P51798,Q15056,Q9H9S5,O95831 34 +Cherry red spot of the macula 0.9473128682705004 2.7448871039567715 0.0060531717482663 0.9999999999994073 0.1766109446917272 10 Q99519,P10619,P07602,P06865,P17900,Q13510,P07686 7 +Pustule 0.9441151224633948 2.740977331964299 0.0061256733434131 0.9999999999995772 0.1766109446917272 3 P07858 1 +Abnormal internal carotid artery morphology 0.9424609029212164 2.737673893276669 0.0061875398181985 0.9999999999996833 0.1766109446917272 2 P21359 1 +Hemihypertrophy 0.942165830628501 2.7364505867759807 0.0062105921497752 0.9999999999997156 0.1766109446917272 2 P31749 1 +Difficulty in tongue movements 0.94037252297623 2.7253942448508415 0.0064224747590915 0.9999999999998942 0.1766109446917272 3 P10253 1 +Posteriorly rotated ears 0.451866356709696 2.7230987792024672 0.0064672717749478 0.9999999999999142 0.1766109446917272 121 Q69YQ0,Q10713,Q9BZK7,P04062,Q15392,P98164,P42892,P21359,Q9H490,P62857,Q8ND04,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P40855,O96028,O43505,Q15427,O43709,Q8WVQ1,P19022,Q15056,Q10471,Q9H9S5,Q4J6C6 26 +Cervical subluxation 0.9388932482230928 2.7192270260084195 0.006543467974108 0.9999999999999398 0.1766109446917272 3 P34059 1 +Abnormality of the alveolar ridges 0.9356602126319636 2.69717344343453 0.0069930836181355 0.9999999999999928 0.1766109446917272 6 P53634,Q15392 2 +Thickened cortex of long bones 0.9334153530518288 2.696349913960622 0.0070103981542886 0.9999999999999932 0.1766109446917272 3 O00754 1 +Somatic sensory dysfunction 0.4502535986030015 2.693741363549544 0.0070654967854815 0.9999999999999948 0.1766109446917272 112 Q8IV08,Q9Y6B6,Q9NQ11,P07602,P06280,Q93063,P05067,Q04656,P07686,O15460,Q9NZ08,P54802,O14773,P01889,Q6UWE0,Q8NCH0 16 +Bacterial endocarditis 0.9309530835054556 2.6898324477619555 0.0071487902070519 0.9999999999999964 0.1766109446917272 2 P04062 1 +Osteochondroma 0.9309530835054542 2.6898324477619453 0.0071487902070521 0.9999999999999964 0.1766109446917272 2 Q93063 1 +Oligosacchariduria 0.9337309852083324 2.6876763919606077 0.0071951088947825 0.9999999999999972 0.1766109446917272 7 O00462,Q99519,P04066,O00754,P10253 5 +Hypolipidemia 0.9282974328710504 2.6787533933842185 0.0073896795701777 0.9999999999999988 0.1766109446917272 2 Q9Y6B6 1 +Hypotriglyceridemia 0.9282974328710504 2.6787533933842185 0.0073896795701777 0.9999999999999988 0.1766109446917272 2 Q9Y6B6 1 +Visual fixation instability 0.9276645999409572 2.6688779459357996 0.0076105100653751 0.9999999999999996 0.1766109446917272 4 O43567,Q13510,Q5KU26 3 +Dysostosis multiplex 0.928682497030366 2.664741397637618 0.007704754621693 0.9999999999999998 0.1766109446917272 10 Q99519,P04066,P10619,O00754,P16278,P54802,P15586 7 +Heparan sulfate excretion in urine 0.9261369776261666 2.6624413161626195 0.0077576095182312 0.9999999999999998 0.1766109446917272 4 P54802,P15586 2 +Absent hypoplastic paranasal sinuses 0.9232692850864158 2.65381327089832 0.0079587855613205 1.0 0.1766109446917272 3 P04066 1 +Neurofibrillary tangles 0.9247472966502984 2.65349510897151 0.0079662925082564 1.0 0.1766109446917272 5 P61916,P05067,Q9Y287 3 +Gastrointestinal infarctions 0.9212156978459688 2.649137992849004 0.0080697374355782 1.0 0.1766109446917272 2 P01889 1 +Generalized abnormality of skin 0.4019333741083964 2.6485623508587968 0.0080834936549065 1.0 0.1766109446917272 234 P07858,Q9BZK7,P56589,O15118,P04062,Q04656,P16278,P51648,Q14739,O75787,P08069,P38571,Q07954,P21359,Q8IZA0,P04066,P06280,Q9C0B1,Q93074,Q14108,P01889,Q8NB49,Q13472,Q15904,P11413,Q8NCH0,Q9UBM7,P23229,P10619,Q9Y487,Q9Y4U1,P40855,P00403,P61916,O60333,Q15427,O43709,Q15125,P00374,O00462,Q99519,Q99829,P35670,P10644,P31749,P51798,Q15056,O60934,P40763,Q13126,O75844,Q99643 52 +Abnormal morphology of the conjunctival vasculature 0.9218889362421682 2.636068781741983 0.0083872728468412 1.0 0.1766109446917272 8 P04066,P10619,P06280 3 +Abnormal bone structure 0.4172664693198941 2.621952259801236 0.0087427676860891 1.0 0.1766109446917272 187 Q13277,P07602,P56589,P34059,P04062,Q04656,Q15392,P16278,P21359,Q9H490,P06280,O43909,P08236,Q14108,P54802,P53634,Q9UBM7,O43292,Q9Y487,Q32P28,Q13510,P40855,Q5JRA6,O96028,O43709,Q15125,Q99519,Q8WVQ1,Q9UDY2,P35670,Q96RR1,P54098,Q93063,O00754,P10644,P31749,P51798,Q15056,P40763,P29992,Q13126,O75844,O95831,Q99643 44 +Abnormal sternum morphology 0.4432482781007681 2.6173687997550807 0.0088610545345779 1.0 0.1766109446917272 123 Q69YQ0,P34059,P04062,Q04656,P16278,Q14739,Q9H173,Q6W2J9,P08069,P42356,P21359,P17480,Q9H490,Q9Y4P3,P08236,Q93074,O43909,Q8NFV4,Q9H2M9,Q8NCH0,Q7LGA3,Q15555,P60953,Q9Y263,Q9Y487,Q13510,O96028,O43709,Q9UHX1,Q99519,Q8NCM8,O00754,P31153,P31749,Q15056,O95831,Q99643 37 +Abnormal abdomen morphology 0.4006415935607585 2.6134328301236533 0.0089637701596678 1.0 0.1766109446917272 231 P07602,P34059,O15118,P04062,Q15392,P16278,P38571,Q9NZ08,P04066,Q5JPH6,P28070,P08236,Q14108,P54802,P01889,P15586,Q15904,P10253,Q07021,P10619,P31751,Q13510,P07686,P61916,P00374,Q99519,P35670,P10644,O00754,P31749,P40763,Q9UN37 32 +Broad metacarpals 0.912658601357327 2.613214019669044 0.0089695114549765 1.0 0.1766109446917272 2 P16278 1 +Abnormality of the ischium 0.912658601357323 2.613214019669027 0.008969511454977 1.0 0.1766109446917272 2 Q8IZA0 1 +Abnormality of dental color 0.9142817261120836 2.612323659750097 0.0089929071988301 1.0 0.1766109446917272 4 P34059 1 +Abnormal respiratory system morphology 0.3912948822392099 2.6108519027244337 0.0090316996637505 1.0 0.1766109446917272 318 Q13277,Q9BZK7,P07602,P34059,Q9H0U9,P04062,O15460,Q15392,P16278,Q9NZ08,P02786,P21359,Q8IZA0,P04066,P06280,P28070,Q93074,P08236,Q14108,O43909,Q92917,P54802,P01889,P15586,P53634,Q8ND04,P10253,Q8NCH0,Q7LGA3,Q9UBM7,Q8TAA9,Q9Y487,Q13510,O96028,Q15125,Q96PZ0,O00462,Q99519,Q93063,O00754,P10644,P31749,P51798,Q15056,P40763 45 +Elevated circulating parathyroid hormone level 0.9127249975587172 2.6093803847761214 0.0090706351389833 1.0 0.1766109446917272 3 P21359 1 +Abnormal thorax morphology 0.3960815338916081 2.5969585591517483 0.0094053270602565 1.0 0.1766109446917272 244 Q8TD19,Q69YQ0,Q8TD16,P34059,O60313,P04062,Q04656,Q8N6M0,P16278,Q96ST3,P51648,Q14739,P60866,Q9H173,O00192,P08069,P21359,P17480,P04066,Q9H490,Q96HY6,P62857,Q93074,P08236,O43909,Q92917,Q9H3S7,P54802,P15586,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,Q9Y487,Q32P28,Q13510,O60333,O96028,Q15427,O43709,Q15125,Q96PZ0,Q99519,Q8WVQ1,P54098,P19022,Q93063,O00754,P31749,P51798,Q15056,O75844,O95831,Q99643 55 +Urinary glycosaminoglycan excretion 0.911256867099415 2.590251056320043 0.0095905959889057 1.0 0.1766109446917272 8 P04066,P34059,P16278,P54802,P15586 5 +Abnormality of skin physiology 0.5235788413755701 2.57596493224836 0.0099960783727921 1.0 0.1779244013565859 96 P10321,P07858,Q13277,Q9NZ08,P38571,P02786,Q07954,P28070,O43909,P01889,Q8ND04,P53634,Q8NCH0,Q9UBM7,P23229,Q5JRA6,P48449,Q9UDY2,P35670,P40763,Q92542 21 +Increased head circumference 0.4390074922362589 2.572221042520873 0.0101048352561552 1.0 0.178778233460745 127 Q10713,P07602,P56589,Q8TD16,Q15392,P98164,Q8IWS0,Q14739,P21359,Q93074,P08236,Q9H3S7,Q13620,Q7LGA3,Q13144,Q13555,Q9UPY3,P40855,P07686,P15291,O43505,Q96PZ0,Q99519,P19022,Q93063,O00754,P31749,P51798,O75844,Q9H9S5,Q99643 31 +Glossitis 0.903187721369536 2.5689910176295316 0.0101995101191592 1.0 0.1791482137217471 3 P01889,O15460 2 +Abnormal uvea morphology 0.438887682443736 2.5554732500924224 0.010604351151142 1.0 0.1821529692491403 107 Q9NR77,Q10713,P56589,P98164,Q96ST3,Q6W2J9,P08069,Q96EK5,P21359,Q9Y4P3,Q9BXW9,P61586,P01889,Q8NFV4,Q7Z392,Q7LGA3,Q9UBM7,Q9Y467,Q9Y297,Q5XKP0,P40855,P41227,O60333,O75381,Q7Z3E5,O43505,O96028,O43709,P04439,Q9UHX1,O15078,P10644,P31153,P31749,Q15056,P29992,Q9H9S5,Q99643 38 +Abnormal tarsal ossification 0.8973148421363143 2.5484167917419267 0.0108213098361538 1.0 0.1821529692491403 2 Q8WVQ1 1 +Abnormality of the tongue 0.4752840560847283 2.541972934356191 0.0110228708819517 1.0 0.1821529692491403 101 O15111,Q10713,Q9H0U9,O15460,P16278,Q9H9B1,P04066,Q9C0B1,P01889,P10253,Q7LGA3,Q9UBM7,Q9Y4U1,Q13510,P40855,P07686,O43709,Q99519,Q9NQ11,O00754,P31749,Q15056,O75844,Q9H9S5,O95831,Q99643 26 +Decerebrate rigidity 0.8954605967800053 2.532152569054008 0.0113364652693213 1.0 0.1821529692491403 4 P07602 1 +Hip osteoarthritis 0.8917084685747938 2.5246181280634765 0.0115824071098511 1.0 0.1821529692491403 2 P01889 1 +Schwannoma 0.8884994387634833 2.506414534909939 0.012196253844662 1.0 0.184758759631574 3 P21359 1 +Ovoid vertebral bodies 0.8886301131487787 2.4936518814609796 0.0126436478919682 1.0 0.184758759631574 7 P54802,P15586,P34059 3 +Retinal thinning 0.8816760106225958 2.4818665348280637 0.0130696217447345 1.0 0.184758759631574 2 P04439 1 +Respiratory tract infection 0.4185517618540569 2.4766341817322512 0.0132627761173673 1.0 0.184758759631574 165 Q13277,P07602,P34059,P04062,O15460,P16278,P02786,P04066,O43909,P08236,P54802,P01889,P15586,P53634,P10253,Q9Y487,Q13510,O96028,O00462,Q99519,O00754,P51798,Q15056,P40763 24 +Anarthria 0.8840696993000215 2.473791604697713 0.0133687653241643 1.0 0.184758759631574 7 Q99720 1 +Flaring of rib cage 0.8804324656911816 2.4718536829982782 0.0134414517696475 1.0 0.184758759631574 3 P34059 1 +Short nose 0.4317543117554312 2.468117358968025 0.013582578023183 1.0 0.1854565345272967 106 Q8WVQ1,Q5KU26,Q9BZK7,P62258,O43909,P04062,P10644,Q15392,Q9NX62,P98164,P42892,Q15056,O43567,Q8NCH0 14 +Endocarditis 0.8800012792915164 2.4618331376729508 0.0138228959464268 1.0 0.1855375891336079 5 P04062,P01889,P10644 3 +Periventricular white matter hyperintensities 0.8810300150708547 2.458670473969508 0.0139452551701213 1.0 0.1855375891336079 8 P17900,P07602 2 +Abnormality of the biliary system 0.430692966529159 2.455104301644425 0.014084371657328 1.0 0.1855375891336079 123 Q8TD19,Q69YQ0,Q10713,P07602,P56589,O15118,P04062,Q04656,Q14739,O75787,P38571,P04066,Q5JPH6,Q14108,Q8NB49,Q15904,P11413,Q9UBM7,Q5XKP0,Q9Y4U1,Q13510,P40855,P61916,O96028,O43709,P00374,Q9UDY2,P35670,P54098,P10644,Q15056,Q9UN37 32 +Hypersplenism 0.8785485996762531 2.447781446694255 0.0143738815040144 1.0 0.1866713927468361 8 Q14108,P04062,P07602 3 +Premature loss of primary teeth 0.87418159711529 2.4449790862506764 0.0144860541796709 1.0 0.1866713927468361 3 P53634 1 +Deep venous thrombosis 0.8733129060252276 2.441237762553658 0.0146370144838572 1.0 0.1866713927468361 3 P31749 1 +Abnormal protein o linked glycosylation 0.8729330960212489 2.4396014765799445 0.0147034724422334 1.0 0.1866713927468361 3 Q15904 1 +Metatarsus valgus 0.8737744861862355 2.4388511218673 0.0147340370380293 1.0 0.1866713927468361 4 O43505,P31749 2 +Cardiorespiratory arrest 0.8716013633483669 2.433861739605665 0.014938700058503 1.0 0.188235739595866 3 P13473 1 +Excessive wrinkling of palmar skin 0.8697108802398438 2.4257073688366164 0.0152785843011888 1.0 0.1889247877456343 3 Q9BZK7 1 +Abnormal heart sound 0.8689736622578416 2.4139465516034284 0.0157807770880398 1.0 0.1906649007733326 5 P04114,P10253 2 +Abnormality of mouth size 0.4267058520750756 2.4133089588579937 0.015808412804428 1.0 0.1906649007733326 128 P34059,P04062,Q15392,P16278,Q96ST3,P08069,O00192,Q9UQR1,Q9H490,Q93074,O43909,Q9H3S7,P15586,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P62258,Q9Y487,Q9NX62,Q7LBC6,Q15427,O43709,Q96PZ0,Q8WVQ1,Q01105,P31749,Q15056,O75844 29 +Thoracolumbar kyphosis 0.869611842167714 2.410534159981355 0.0159291795466782 1.0 0.1906649007733326 7 P08236,P04062,O00754 3 +Polar cataract 0.8669696183307752 2.409368903917334 0.015980136023131 1.0 0.1906649007733326 4 Q9Y287 1 +Saccadic oscillation 0.8633412042502878 2.398176967778873 0.0164769025900761 1.0 0.1906649007733326 3 P51798,P04062 2 +Opsoclonus 0.8633412042502878 2.398176967778873 0.0164769025900761 1.0 0.1906649007733326 3 P51798,P04062 2 +Cervical spinal canal stenosis 0.8629810700658953 2.396617870156787 0.0165471704437998 1.0 0.1906649007733326 3 O43909 1 +Motor deterioration 0.8650394999713493 2.3930599468480076 0.0167085108987832 1.0 0.1906649007733326 6 O75503 1 +Muscle flaccidity 0.8608221868170394 2.387265859217271 0.0169742112543125 1.0 0.1906649007733326 3 P13473 1 +Aplasia hypoplasia involving the sinuses 0.8622336044818445 2.384551007049407 0.0170999772928059 1.0 0.1906649007733326 5 P04066 1 +Short stepped shuffling gait 0.8589554440837881 2.38426436043738 0.0171133038496871 1.0 0.1906649007733326 2 P04062 1 +Abnormal subcutaneous fat tissue distribution 0.8609297825370306 2.3788534671795305 0.017366577971378 1.0 0.191735290603048 5 Q9BZK7,P31749 2 +Aplasia hypoplasia of the abdominal wall musculature 0.8607482200702936 2.374238359538246 0.0175851942420017 1.0 0.1923824535375162 6 O00462,Q8WVQ1 2 +Abnormal visual fixation 0.8615609542143849 2.3728796487539463 0.0176500139314765 1.0 0.1923824535375162 8 O43567,P04062,Q13510,Q5KU26 4 +Abnormal macrophage morphology 0.8613355002727738 2.3718814003210533 0.0176977704866683 1.0 0.1923824535375162 8 Q99519,O15118,Q13510,P16278,P61916 5 +Focal motor status epilepticus 0.8560047211566837 2.371509000741619 0.0177156151952813 1.0 0.1923824535375162 2 Q96RR1 1 +Abnormality of the neck 0.4013023621504749 2.362617293310017 0.0181463980784519 1.0 0.1956264200551285 185 Q8TD19,Q9BZK7,P56589,Q04656,Q8N6M0,P16278,Q14739,P60866,O00192,P08069,Q96EK5,Q9Y3D3,Q07954,P21359,Q96HY6,P62857,Q9C0B1,Q93074,P08236,Q92917,P15586,Q7LGA3,Q9UBM7,Q15555,P62258,Q9Y487,P40855,O96028,Q9ULC3,O43709,Q99720,Q15125,Q8WVQ1,Q9NQ11,P19022,O00754,O96000,P31749,Q15056,Q9NUM4,O60934,O75844,O95831 43 +Erlenmeyer flask deformity of the femurs 0.8560532559604496 2.361868520157523 0.0181830897226138 1.0 0.1956264200551285 4 P04062,P07602 2 +Duplication of phalanx of hallux 0.8533494336492775 2.354818796705036 0.0185317400025388 1.0 0.1963406151863161 3 Q8WVQ1 1 +Abnormal cervical spine morphology 0.8553712574176412 2.354522834237626 0.0185465041826777 1.0 0.1963406151863161 5 P04066 1 +Onset 0.3586089534267177 2.3505017855569386 0.0187481177095347 1.0 0.1963406151863161 406 Q8TD19,Q13277,O15111,Q8TD16,P07602,P34059,Q99643,Q69YQ0,O15118,P04062,Q04656,Q96N67,P16278,Q04446,O14773,O75787,O00584,Q9H173,P08069,P38571,Q96EK5,Q969X5,Q14574,Q9Y6B6,Q5KU26,Q5JPH6,P06280,P62857,Q9H490,P06865,Q10713,Q9NQX3,P54802,P50897,Q8NB49,Q13472,Q70HW3,Q15904,Q07021,Q7LGA3,P23229,O43292,Q8IV08,Q13144,P31751,Q5XKP0,Q9Y4U1,Q13510,P07686,P61916,O60333,O43567,Q9NWW5,Q7Z3E5,Q5JRA6,O43505,Q15125,Q14203,P41440,Q9UDY2,Q9NQ11,Q9UBB6,Q96RR1,P54098,Q93063,P10644,Q96N66,P31749,Q6IA86,P51798,P40763,P35270,Q9H9S5,O95831,Q4J6C6 75 +Peters anomaly 0.8503983475951641 2.34722329756975 0.0189139157901911 1.0 0.1963406151863161 2 P19022 1 +Abnormal liver morphology 0.3793278683101529 2.3439657228129485 0.0190799248049429 1.0 0.1963406151863161 252 P07602,P34059,O15118,P04062,Q04656,P16278,P38571,P11717,Q9Y6B6,P04066,Q5JPH6,P28070,O43909,P08236,Q14108,P54802,P15586,P53634,Q15904,P10253,Q07021,P04114,P10619,P31751,Q13510,P07686,P61916,P00374,Q99519,Q9UDY2,P35670,O00754,P40763,Q9UN37 34 +Epidermal nevus 0.8486279138388758 2.339540378341519 0.0193074843708296 1.0 0.1963406151863161 2 P31749 1 +Hoarse cry 0.848037769253451 2.336977939013259 0.0194403312086663 1.0 0.1963406151863161 2 Q13510 1 +Pulmonary infiltrates 0.8528314746206727 2.336553153738735 0.0194624307283908 1.0 0.1963406151863161 7 P04062,Q13510,P01889 3 +Follicular hyperkeratosis 0.8517966036875314 2.331970876298917 0.0197022233260393 1.0 0.1963406151863161 7 Q07954 1 +Cloverleaf skull 0.848062603326079 2.331791876608285 0.0197116425938068 1.0 0.1963406151863161 3 O43909 1 +Joint subluxation 0.8491856259792229 2.3233290826817985 0.0201614806244032 1.0 0.196803675020181 6 P34059 1 +Cataplexy 0.8465721682319719 2.320408525873375 0.0203187881105904 1.0 0.1971092478426939 4 P61916 1 +Hypoplasia of the iris 0.8481285497408243 2.3186606231283564 0.0204134452023134 1.0 0.1972023862565158 6 Q7LGA3,P98164,P08069 3 +Abnormality of the vasculature of the eye 0.6454698914102202 2.317422390424899 0.0204807338214563 1.0 0.19744108675695 76 P21359,O00462,Q99519,P04066,P10619,P07602,P06280,P28070,P06865,P17900,Q13510,P16278,P07686,Q15056,P01889,Q9NZ08,P02786,P04439 18 +Flat forehead 0.8461269308871929 2.313913341518897 0.020672476137282 1.0 0.1988760826733961 5 Q93063,Q8NCH0 2 +Abnormal immune system morphology 0.4079606367442585 2.312868146039778 0.0207298896498953 1.0 0.1990155244442329 164 Q9BZK7,O15118,P04062,P16278,O75787,P38571,P02786,P21359,P04066,P62857,P28070,O43909,Q14108,O43464,P01889,Q14126,P53634,Q15904,Q8TAA9,Q9Y4U1,Q13510,P61916,Q99519,P09493,P10644,O00754,P51798,O60934,P40763 29 +Narrow nasal bridge 0.8455257124377666 2.3112659555107755 0.0208181692579021 1.0 0.1993320505647573 5 O43567 1 +Mild short stature 0.8441098317094875 2.309609800378753 0.0209097665362183 1.0 0.1993320505647573 4 Q8WVQ1,P10644,Q13555 3 +Abnormality of lysosomal metabolism 0.8457759492925083 2.308262076823192 0.0209845643445243 1.0 0.1993320505647573 6 Q13510,P07602 2 +Progressive psychomotor deterioration 0.8469556270425356 2.3079852756842394 0.0209999554618685 1.0 0.1993320505647573 8 P07686,P07602 2 +Reduced visual acuity 0.4190228776964857 2.3068902187817204 0.0210609409533555 1.0 0.1993320505647573 126 Q13277,Q10713,P07602,O60313,P17900,P16278,Q6W2J9,Q9NZ08,P21359,Q9Y6M9,O43395,P06865,P50213,P61586,P51797,P01889,P50897,Q96MF7,Q07021,Q8N183,Q15555,Q13144,P60953,Q9Y467,Q9Y4U1,P07686,P41227,Q7Z3E5,O43505,Q9UHX1,Q9P032,O75489,O15078,P54098,O96000,P31749,P22570,P51798,Q9H9S5 39 +Abnormality of cardiovascular system electrophysiology 0.4186641470178587 2.3021189775068556 0.0213284634841752 1.0 0.2006086920408128 126 Q69YQ0,P07602,Q9H0U9,P04062,O15460,P42892,Q07954,P21359,Q9H490,P06280,O43464,P01889,Q13472,Q14126,P10253,P04114,P13473,P40855,P00403,O60333,Q9H2U2,O43709,Q9BQP7,Q99519,Q96RR1,P54098,P09493,P19022,P31749,Q15056,P29992,Q99643 32 +Calvarial hyperostosis 0.8425811537612308 2.2982888997233353 0.0215453518073822 1.0 0.2012789492274186 5 P31749 1 +Auditory hallucinations 0.8413380898512954 2.2974388135895047 0.0215937497498894 1.0 0.2012789492274186 4 Q9Y4U1,Q9NWW5 2 +Atrophic scars 0.8445799422976957 2.297386271392176 0.0215967442372686 1.0 0.2012789492274186 8 P53634,Q8NCH0,Q07954 3 +Flattened epiphysis 0.8410732254778197 2.2962749181101056 0.0216601672772227 1.0 0.2012789492274186 4 Q8WVQ1 1 +Pleuritis 0.8393993750067047 2.2939314546367515 0.0217944363156663 1.0 0.201718166059371 3 P01889 1 +Orchitis 0.8393993750067047 2.2939314546367515 0.0217944363156663 1.0 0.201718166059371 3 P01889 1 +Abnormal facial shape 0.3741927742044927 2.288616882586882 0.0221016221110326 1.0 0.2023797592723937 316 Q69YQ0,Q9BZK7,Q10713,P34059,P56589,P04062,Q04656,Q8N6M0,P16278,Q9H9B1,Q8IWS0,Q96ST3,O00584,P08069,O00192,Q9UQR1,Q9Y3D3,P21359,P49591,P04066,Q9H490,P15311,P06280,Q9C0B1,Q93074,P08236,O43909,Q9H3S7,Q13620,P54802,P15586,Q14671,Q8NCH0,Q7LGA3,Q15555,Q13555,P10619,Q9Y487,Q9Y4U1,Q32P28,Q13510,P40855,P07686,Q9NX62,O43567,Q7Z3E5,O96028,O43709,Q15125,Q96PZ0,P39880,O00462,Q99519,Q8WVQ1,Q9UBB6,Q01105,Q93063,O00754,P10644,P31749,Q96N66,Q15056,Q10471,P40763,O75844,O95831 66 +Talipes valgus 0.8400151535928019 2.286965201825474 0.0221978542988048 1.0 0.2023797592723937 5 Q93063 1 +Abnormal upper limb bone morphology 0.4176678774290292 2.285923773003069 0.0222587184017513 1.0 0.2023797592723937 109 P34059,Q04656,Q8N6M0,P16278,Q9H1A4,Q14739,Q9H173,Q6W2J9,Q9Y4P3,P08236,Q93074,Q9BXW9,Q9H3S7,O43909,Q8NFV4,P53634,Q7LGA3,Q9UBM7,Q32P28,Q9NX62,O43567,O96028,Q9ULC3,Q15427,O43709,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,Q8NCM8,Q93063,P10644,P31749,P51798,Q15056,O75844 36 +Abnormality of coordination 0.3735391685551256 2.277516460345423 0.0227554028196477 1.0 0.2055181551246191 332 Q10713,P07602,Q04446,Q7KZN9,P56589,O15118,P04062,P05067,Q8N6M0,Q96IX5,O75503,P16278,O15460,O14773,O75787,O00584,Q9Y287,Q9H173,Q9NZ08,P07384,P21359,Q14108,Q9NQX3,P01889,P50897,Q13472,Q14671,Q8N183,O43292,Q8IV08,P04114,P62258,Q9Y487,Q5XKP0,Q9Y4U1,Q13510,P40855,P07686,P00403,P61916,Q6P4A7,O60333,Q9NWW5,Q7Z3E5,O96028,O43709,Q99720,P00374,P41440,Q99519,Q9NQ11,Q9BV79,Q01105,P35670,Q96RR1,P54098,O00754,O96000,P31749,Q9GZZ9,Q15056,Q9NUM4,O14949,P40763,P35270,Q9UN37,Q9H9S5,O95831,Q99643 69 +Pediatric onset 0.3803888390886543 2.2770845015088734 0.0227811800159702 1.0 0.2055181551246191 234 P07602,P34059,O15118,Q04656,Q96N67,P16278,O14773,O75787,O00584,Q9H173,P38571,Q14574,Q9Y6B6,Q5JPH6,P62857,P06280,P06865,Q9NQX3,P54802,Q70HW3,Q15904,O43292,Q13144,Q9Y4U1,Q13510,P07686,Q5JRA6,Q9UDY2,Q9NQ11,Q9UBB6,Q93063,P31749,P51798,P40763,P35270,O95831 36 +Abnormality of lower limb joint 0.399005649107646 2.275644225419971 0.0228673120806151 1.0 0.2058946138209945 176 Q9NR77,Q8TD16,P07602,P34059,Q04656,P16278,Q9H1A4,Q8IWS0,O75787,Q9H173,Q6W2J9,O00192,P07384,Q969X5,P21359,Q96HY6,Q9Y4P3,P08236,O43909,Q9BXW9,Q9NQX3,Q8NFV4,Q7LGA3,Q9UBM7,P62258,Q9Y487,Q13510,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,P63241,Q15125,O43709,Q9UHX1,Q8WVQ1,Q8NCM8,Q93063,O00754,P43034,P31749,Q15041,P51798,Q15056,O75844,Q9H9S5,O95831 48 +Mucosal telangiectasiae 0.8399801272306548 2.271611208106699 0.0231100033316398 1.0 0.2076765221876237 11 Q8IZA0,P10619,P06280 3 +Spontaneous hematomas 0.8318087931543117 2.2662238746857195 0.02343767957995 1.0 0.2094008515160043 2 Q04656 1 +Functional abnormality of the inner ear 0.3736813802976226 2.254792606024961 0.024146349610254 1.0 0.2141662897001003 259 Q9BZK7,P07602,P56589,O60313,P04062,O15460,Q04656,P98164,P42892,O00584,P23634,Q9NZ08,P21359,P62857,P06280,O43395,Q93074,Q9C0B1,O43464,P33993,P01889,Q13472,Q14126,Q15904,Q07021,Q8N183,Q7LGA3,Q9UBM7,P55263,Q15555,Q9Y297,Q9Y263,Q5XKP0,Q7LG56,Q13510,P40855,P00403,O60333,O43567,Q5JRA6,O96028,Q9ULC3,O43709,Q15125,Q96PZ0,O00303,P41440,Q99519,O75489,Q96RR1,P09493,P10644,O00754,P54098,O96000,Q15056,P40763,Q9UN37,O75844,O95831,Q99643 61 +Abnormality of the nasolabial region 0.8342465251492124 2.253912577395948 0.0242016682775183 1.0 0.2141662897001003 7 P21359,Q8NCH0 2 +Prominent nasolabial fold 0.8342465251492124 2.253912577395948 0.0242016682775183 1.0 0.2141662897001003 7 P21359,Q8NCH0 2 +Loss of voice 0.8285220214114197 2.2461709177273512 0.0246930622681365 1.0 0.216905514500128 3 Q13510 1 +Recurrent sinopulmonary infections 0.8317648588100832 2.2460888031757973 0.0246983203916471 1.0 0.216905514500128 6 Q9Y487,P40763,P02786 3 +Bone cyst 0.8284807323890088 2.2407687142055392 0.0250410604840114 1.0 0.2182620253089494 4 P21359,P31749 2 +Pituitary growth hormone cell adenoma 0.8239033188374849 2.2258158349175674 0.0260265197168803 1.0 0.2214177620840292 3 P10644 1 +Hernia 0.4092745057271513 2.2235328595579684 0.0261798901892864 1.0 0.2214177620840292 141 Q8TD19,O15111,Q69YQ0,Q10713,P34059,Q04656,P16278,Q9H9B1,P98164,Q96ST3,Q14739,Q6W2J9,O00192,P04066,P62857,Q9C0B1,Q9Y4P3,P08236,Q93074,Q9BXW9,Q9NQX3,Q13620,Q8NFV4,Q8WYQ5,Q8NCH0,Q9UBM7,Q15555,P60953,P62258,Q9Y487,Q32P28,O43567,Q7LBC6,O96028,Q9ULC3,O43709,Q9UHX1,Q99519,Q8NCM8,O00754,P31153,P43034,Q15056 43 +Long ear 0.821776335202119 2.2222086598094077 0.0262692075002426 1.0 0.2214177620840292 2 Q7LBC6 1 +Abnormal location of ears 0.3721823615926938 2.2181298432156167 0.0265459805327634 1.0 0.2214177620840292 254 O15111,Q69YQ0,Q10713,Q9BZK7,P56589,P04062,Q8N6M0,Q15392,P16278,P98164,P42892,Q14739,P60866,O75787,O00192,P08069,Q96EK5,P21359,Q9H490,P62857,Q93074,Q92917,P15586,Q14671,Q8ND04,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q13555,P62258,Q9Y487,Q9Y4U1,P40855,Q7Z3E5,O43505,O96028,Q15427,Q15125,Q96PZ0,O43709,Q9ULC3,Q99519,Q8WVQ1,P19022,P31749,Q15056,Q10471,O75844,Q9H9S5,O95831,Q4J6C6 52 +Abnormal renal vascular morphology 0.8242104573940018 2.216912193315121 0.0266290923689753 1.0 0.2214177620840292 5 P21359,P04114 2 +Ineffective esophageal peristalsis 0.8248144308044447 2.2150921628296993 0.0267537392628223 1.0 0.2214177620840292 6 P06280 1 +Weak voice 0.8241633060890147 2.212183124444681 0.0269540143920967 1.0 0.2214177620840292 6 P04062,O75787,Q14203 3 +Abnormal urine metabolite level 0.3970721206216385 2.2099588521440037 0.0271080181611669 1.0 0.2214177620840292 172 O15111,Q99643,P34059,P04062,P16278,P98164,P21359,P04066,P06280,P08236,Q14108,Q9Y697,Q9NQX3,O43464,P61457,P54802,P15586,P11413,P10253,Q5XKP0,Q9Y4U1,P00403,O60333,Q5JRA6,O43709,O00462,Q99519,P35670,P54098,O00754,O96000,Q15056,P40763,P46020,Q9H9S5,Q4J6C6 36 +Beaking of vertebral bodies 0.8254834876218387 2.2092591180549475 0.0271566230045068 1.0 0.2214177620840292 9 P21359,P04066,P16278 3 +Metaphyseal spurs 0.8188256122749948 2.209222973221131 0.02715913573417 1.0 0.2214177620840292 2 Q04656 1 +Absent tibia 0.8188256122749948 2.209222973221131 0.02715913573417 1.0 0.2214177620840292 2 Q04656 1 +Long neck 0.8200847176613195 2.208953131520035 0.0271779010289667 1.0 0.2214177620840292 3 Q04656 1 +Fibroadenoma of the breast 0.8207023052344891 2.20631550413084 0.0273619165680274 1.0 0.2214177620840292 4 P31749 1 +Meningitis 0.8235223838963575 2.2058911361814273 0.0273916230013011 1.0 0.2214177620840292 7 Q9NZ08,P01889,O15460,P02786 4 +Uplifted earlobe 0.8193371682950018 2.2056484306141746 0.0274086252827761 1.0 0.2214177620840292 3 Q9BZK7 1 +Abnormal bleeding 0.4106103725543577 2.20354499449022 0.0275563593127847 1.0 0.2218880824528254 105 Q9BZK7,P04062,O15460,P05067,Q04656,Q14739,P60866,O00192,Q9NZ08,P21359,Q14108,P11117,P12814,P01889,Q8NCH0,Q9Y487,Q9Y4U1,O60333,Q99519,P35670,P10644,P31749,P51798,P40763,P29992,Q13126,O75844,Q99643 28 +Enlarged ovaries 0.8210731827278639 2.20294378401214 0.0275987111106337 1.0 0.2218880824528254 5 P10644,P31749 2 +Movement abnormality of the tongue 0.8209809902868694 2.2025329930435347 0.0276276812309008 1.0 0.2218880824528254 5 P10253 1 +Abnormal urine carbohydrate level 0.8249569834147633 2.2014853346771983 0.027701683774822 1.0 0.2218880824528254 13 O00462,Q99519,P04066,O00754,P10253 5 +Abnormal spinal meningeal morphology 0.8170551785187201 2.2014228474547277 0.0277061030278598 1.0 0.2218880824528254 2 P21359 1 +Prominent sternum 0.8182832620396714 2.1955748872218734 0.0281223853446217 1.0 0.2239051371492287 4 P16278,P34059 2 +Pulmonary embolism 0.8187788067157573 2.1880924382769926 0.0286628696154063 1.0 0.2263470412537762 6 Q9NZ08,P01889,P31749 3 +Myelopathy 0.8164036975083779 2.187221113314687 0.0287263863038238 1.0 0.2263470412537762 4 Q93063,P34059 2 +Conjunctival hamartoma 0.8150974656353478 2.186883847466554 0.0287510043775014 1.0 0.2263470412537762 3 P31749 1 +Esophageal varix 0.8183303712743415 2.1860833457648265 0.0288095082031283 1.0 0.2264232026066204 6 P35670,P04062 2 +Scaphocephaly 0.814911475798819 2.180583634767104 0.0292142266586765 1.0 0.2276745697752659 4 P40855 1 +Upper motor neuron dysfunction 0.3506061021344343 2.1795822633504054 0.029288440726678 1.0 0.2278699658550436 394 Q10713,P07602,Q04446,P56589,O60313,P17900,Q15392,O75503,Q9NVC6,O14773,P60866,O00584,Q9Y287,P49591,P17480,P04066,Q5KU26,P11117,P50897,Q13510,P07686,P61916,O43567,O43505,Q99720,Q99519,Q9NQ11,Q9BV79,O00754,P31749,Q8TD16,O15118,P04062,Q8N6M0,P16278,Q9H173,P21359,Q93074,P01889,Q01105,Q15041,Q96N66,Q15056,Q9NUM4,Q9UN37,Q9UBX3,Q04656,Q9NZ08,P07384,Q5JPH6,O43909,Q9NQX3,Q13423,Q14671,Q9Y487,P40855,P23258,Q9UBB6,Q6IA86,P35270,O95831,Q7KZN9,P51648,O75787,Q9H490,O43464,Q8N183,O43292,Q13144,Q5XKP0,P00403,O43709,Q14203,P39880,P41440,P54098,Q9GZZ9,Q9H9S5 78 +Bilateral talipes equinovarus 0.8154730989695987 2.1779585560082104 0.0294091223790529 1.0 0.2280436462736929 5 O00754,Q15392 2 +Abnormal circulating copper concentration 0.8152135768584711 2.176799082580205 0.0294955615408982 1.0 0.2283320849167701 5 P35670,Q15904 2 +Impaired oropharyngeal swallow response 0.8111537326645034 2.175375324872539 0.0296020020396787 1.0 0.2287741390966508 2 Q9Y263 1 +Appendicular hypotonia 0.8108586603717727 2.1740710496489393 0.0296997997556169 1.0 0.2291480390462495 2 P04062 1 +Hyperphosphatemia 0.812017197512223 2.1732273265224644 0.0297632120495321 1.0 0.2292558376639211 3 P10644 1 +Pneumothorax 0.8137082621553968 2.165350611397584 0.030360845224193 1.0 0.232315576410203 6 Q8NCH0 1 +Glomus jugular tumor 0.8090991670033947 2.160271891533221 0.030751627614606 1.0 0.2326187557078763 3 P21359 1 +Gingivitis 0.8090010671471798 2.1542481915313503 0.0312207134153514 1.0 0.2351299916063145 4 P53634 1 +Congenital hypothyroidism 0.8088042440711709 2.1533699407850264 0.0312896160322564 1.0 0.2351299916063145 4 Q13423,P10644 2 +Pain 0.3870399716856776 2.150288613026067 0.0315323925496648 1.0 0.2354520197307505 188 Q9BZK7,P07602,O60313,P04062,Q04656,Q9UBS4,O15460,P42892,Q14739,P60866,O00192,Q9NZ08,Q07954,P21359,Q96HY6,P06280,P28070,Q14108,Q13423,P01889,Q70HW3,P11413,P04114,Q8TAA9,Q13510,P07686,O60333,O43709,Q14203,P35670,Q96RR1,P19022,Q93063,P10644,P54098,P31749,P51798,Q15056,P40763,P46020,P29992,O75844,Q9H9S5,Q99643 44 +Septate vagina 0.8046621422248277 2.1466396087215043 0.0318219840329963 1.0 0.2368793944897074 2 Q9UBM7 1 +Involuntary movements 0.3545008507380024 2.146592722299126 0.0318257198117506 1.0 0.2368793944897074 352 Q8TD16,P07602,Q9UBX3,Q10713,Q9H0U9,O60313,P17900,P05067,P04062,Q96IX5,O75503,Q04656,Q96N67,Q9H9B1,O14773,O75787,O00584,Q9Y287,Q9NVC6,P07384,Q969X5,P21359,P49591,P17480,P06280,O43909,Q14108,Q9NQX3,O43464,P61457,P50897,Q14671,O43292,Q9BWD1,Q5XKP0,Q9Y4U1,Q13510,P07686,P00403,P61916,Q6P4A7,O60333,Q9NWW5,Q7Z3E5,O96028,O43709,Q99720,Q14203,P00374,P39880,P41440,Q99519,Q9NQ11,Q9BV79,Q01105,P35670,Q9UBB6,Q96RR1,Q93063,P54098,Q96N66,P31749,Q6IA86,P51798,Q15056,Q9NUM4,O14949,Q9GZZ9,P29992,P35270,Q9UN37,Q6UWE0,Q9H9S5,O95831,Q99643 75 +Pulmonary cyst 0.8071298322230904 2.1406126514254904 0.0323052876988394 1.0 0.2374003471624699 5 P31749 1 +Abnormality of pelvic girdle bone morphology 0.3992229243697883 2.1360177248872043 0.0326779691049186 1.0 0.2397590866131448 156 Q8TD16,P34059,Q04656,P16278,Q8IWS0,Q14739,Q9H173,Q969X5,Q8IZA0,Q96HY6,O43909,P08236,Q9NQX3,Q9H3S7,P01889,Q7LGA3,Q9UBM7,Q8TAA9,P62258,Q9Y487,O43567,Q7LBC6,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,O43709,Q8N3R9,Q9UHX1,Q8WVQ1,Q8NCM8,Q93063,O00754,P31749,P51798,Q15056,O75844,Q9H9S5,O95831 40 +Capillary hemangioma 0.8070591369719708 2.1255306760147747 0.0335423572045627 1.0 0.2434218009249787 9 Q9UBM7,Q7LGA3,P31749 3 +Sparse body hair 0.8062319478165958 2.1193297298136393 0.034062610839306 1.0 0.2445020533465359 10 P53634,Q14574 2 +Abnormal foot bone ossification 0.8008761609004658 2.117926957106862 0.0341812541931318 1.0 0.2449744601136824 4 Q8WVQ1,Q15125 2 +Depression 0.4037494709867564 2.1133141041723023 0.0345738923300928 1.0 0.2454635501997589 106 P07602,P04062,O15460,Q9H9B1,P60866,O00192,P49591,P06280,O43464,P01889,P50897,P00403,Q9NWW5,O43709,Q14203,Q9NQ11,Q9UBB6,P35670,Q96RR1,P54098,P10644,O00754,Q96N66,Q15056,Q9NUM4,P29992 26 +Abnormal conjunctiva morphology 0.798342038539811 2.113253012216632 0.0345791181157331 1.0 0.2454635501997589 27 O00462,P04066,P10619,P28070,P06280,Q13510,P31749,P01889,P02786 9 +Hepatomegaly 0.3856284145036358 2.1090243411430456 0.0349424806389937 1.0 0.2473714240046015 184 P07602,P34059,O15118,P04062,P16278,P38571,P04066,Q5JPH6,P28070,P08236,Q14108,P54802,P15586,Q15904,P10253,Q07021,P31751,Q13510,P07686,P61916,P00374,Q99519,P35670,O00754,Q9UN37 25 +Abnormal peristalsis 0.8016375076031743 2.1071393700633005 0.035105500552113 1.0 0.2475533573495464 7 P06280 1 +Macrogyria 0.7995601537915131 2.1016106947785227 0.0355873922474512 1.0 0.2478250642233308 6 Q15392 1 +Limb joint contracture 0.4026377346087092 2.1015301288317265 0.0355944560648562 1.0 0.2478250642233308 105 Q7LGA3,Q8IZA0,Q8WVQ1,Q8TD16,Q93074,O43909,Q8N6M0,Q15392,P42892,P40763,Q99720 11 +Diastasis recti 0.7956920823071142 2.1005208155665533 0.0356830514897019 1.0 0.2480694299216612 3 Q8NCH0 1 +Neurofibromas 0.7999359054469953 2.0994191541343907 0.0357799676776584 1.0 0.2483708235348836 7 P31749,Q07954 2 +Coarse facial features 0.6284073983187322 2.096747234344539 0.0360159567805518 1.0 0.2496352639632567 74 P34059,P16278,Q9H9B1,Q8IWS0,Q9UQR1,P21359,P04066,P06280,O43909,P08236,Q93074,P54802,P15586,Q7LGA3,P10619,P07686,Q99519,Q93063,O00754,Q15056,P40763,O95831 22 +Right ventricular dilatation 0.7931543228090763 2.0954855085514144 0.0361278553343316 1.0 0.2499950266790674 2 P19022 1 +Abnormal inflammatory response 0.3656180806491419 2.094947187432362 0.0361756874922696 1.0 0.2499950266790674 252 P10321,P07858,Q9BZK7,P04062,Q04656,O15460,P16278,P51648,Q9NZ08,P11717,P02786,P21359,P28070,O43909,P08236,Q9Y697,Q9NQX3,P01889,P53634,Q8ND04,Q8NCH0,Q9UBM7,P23229,Q9Y4U1,Q13510,Q5JRA6,O96028,Q15125,P48449,P04439,P35670,P10644,O00754,P31749,P51798,Q15056,O60934,P40763,Q13126,Q92542 40 +Abdominal aortic aneurysm 0.7948036610569987 2.090691655691237 0.0365557134779692 1.0 0.2514968002927945 4 P01889,O15460,P31153 3 +Exaggerated startle response 0.7990533330438816 2.0889251491159713 0.0367144615820327 1.0 0.2517001447013905 9 P16278,P06865,P17900,P07686 4 +Decreased pulmonary function 0.7930652297018561 2.0887704402830733 0.0367283925036874 1.0 0.2517001447013905 3 P31749 1 +Myoclonus 0.4022761058557805 2.0859499935598667 0.0369831530287094 1.0 0.2528337304786852 110 P00374,Q99519,Q9NQ11,P07602,Q9BV79,Q01105,Q9H0U9,Q14108,P05067,Q13510,P31749,O75503,P04062,O14773,Q9NWW5,P50897 16 +Abnormal tendon morphology 0.3725969353767072 2.0855140279117874 0.0370226661623953 1.0 0.2528337304786852 217 Q8TD16,P04062,Q8N6M0,Q15392,P42892,Q9H173,Q8IZA0,P04066,P28070,Q93074,P08236,P50897,P15586,Q8NCH0,Q7LGA3,P04114,Q13510,O43567,Q99720,P48449,Q8WVQ1,Q15041 22 +Type ii lissencephaly 0.7924183157070533 2.0799726014333295 0.0375280459969964 1.0 0.2534704381514092 4 O43505 1 +Abnormality of the knee 0.4677276009287715 2.079661551842347 0.037556586992163 1.0 0.2534704381514092 97 Q8TD16,P34059,Q04656,P16278,Q969X5,P21359,P08236,Q7LGA3,Q13510,Q9NX62,Q5JRA6,Q9ULC3,Q15125,Q8WVQ1,Q93063,O00754,Q15041,P51798,Q15056,O95831 20 +Disproportionate short trunk short stature 0.7945545436185425 2.078959905834091 0.0376210357964792 1.0 0.2534704381514092 6 P34059 1 +Patchy changes of bone mineral density 0.7907940949693375 2.078599878642767 0.0376541421530434 1.0 0.2534704381514092 3 Q13126 1 +Neuroinflammation 0.7920644300460513 2.078381348672097 0.0376742491971975 1.0 0.2534704381514092 4 Q9NZ08,P01889 2 +Dysphagia 0.3982476679819117 2.072681245860059 0.0382019542594278 1.0 0.2543789732603608 142 Q69YQ0,P07602,O60313,O15118,P04062,P05067,Q04656,Q9NVC6,Q14739,Q9BUF5,P21359,Q8IZA0,P17480,Q14108,P01889,P15586,Q13472,Q8N183,Q9Y263,Q7LG56,Q13510,P61916,P63241,Q99720,Q14203,P39880,Q9UHX1,Q9BQP7,Q99519,Q9NQ11,Q9BV79,Q01105,P35670,Q96RR1,P54098,Q93063,Q99643 37 +Aplasia hypoplasia of the sacrum 0.789323267533519 2.072007626510692 0.0382647299663618 1.0 0.2543789732603608 3 P04066 1 +Hypertonia 0.3457668900744751 2.0717233403419244 0.0382912493715186 1.0 0.2543789732603608 396 Q10713,P07602,Q04446,P56589,O60313,P17900,P05067,Q15392,O75503,Q9NVC6,Q14739,P60866,O00584,Q9Y287,P49591,P17480,P04066,Q5KU26,P06865,P11117,P50897,Q7LGA3,Q13510,P07686,P61916,O43567,O43505,Q99720,Q99519,Q9NQ11,Q9BV79,O00754,Q8TD16,O15118,P04062,Q8N6M0,P16278,Q9H173,P61457,Q9UBM7,Q01105,Q15041,Q96N66,Q15056,Q9NUM4,Q9UN37,Q9BZK7,Q9UBX3,Q04656,P07384,Q5JPH6,O43909,Q9NQX3,Q14671,Q9Y487,P40855,P23258,Q15125,Q9UBB6,Q6IA86,P35270,O95831,Q7KZN9,P51648,O75787,Q9H490,Q9C0B1,O43464,Q8N183,O43292,Q13144,Q5XKP0,O43709,Q14203,P39880,Q96RR1,P54098,Q9GZZ9,Q9H9S5 79 +Agenesis of maxillary incisor 0.7875479492475655 2.070466095168141 0.0384087178976957 1.0 0.2544303212737358 2 Q6W2J9 1 +Fractures of the long bones 0.7877772258726352 2.0650735156544724 0.0389160448923977 1.0 0.2574232527333072 3 P51798 1 +Aortic dissection 0.7894432745440065 2.0609670280579513 0.039306185792757 1.0 0.2577974307227925 5 P01889,O15460 2 +Abnormal tissue metabolite concentration 0.7931563180093415 2.0527048696556243 0.0401012094851365 1.0 0.2618397762766284 16 P06865,P17900,P07602,P06280 4 +Limitation of joint mobility 0.3988248926613523 2.052428558853131 0.0401280314175771 1.0 0.2618397762766284 105 Q8TD19,Q8TD16,Q04656,O15460,P16278,P51648,Q969X5,Q93074,P08236,O43909,Q9NQX3,Q92917,P54802,P01889,P15586,Q7LGA3,Q8TAA9,Q15427,O43709,Q93063,O00754,P31749,Q15056,O75844 24 +Malrotation of small bowel 0.7856693044788258 2.049581523178748 0.0404052849893257 1.0 0.2618397762766284 4 Q8NCH0 1 +Abnormal aldolase level 0.7853038153772651 2.047933064934132 0.0405665584628427 1.0 0.2618397762766284 4 O43505,Q9H173 2 +Avascular necrosis of the capital femoral epiphysis 0.7859416112607562 2.045122252968537 0.0408428069133537 1.0 0.2618397762766284 5 Q9H173 1 +Posterior pituitary dysgenesis 0.782653939655453 2.0420605299096755 0.0411455274710026 1.0 0.2627986375799439 3 Q9UHX1 1 +Agenesis of cerebellar vermis 0.7804662142224889 2.038771488681704 0.041472839099327 1.0 0.2640380426124215 2 Q10713 1 +Neonatal breathing dysregulation 0.7804662142224889 2.038771488681704 0.041472839099327 1.0 0.2640380426124215 2 Q10713 1 +Elevated serum acid phosphatase 0.7831903515681218 2.038395441849443 0.0415104017822849 1.0 0.2640380426124215 4 P07602 1 +2 3 finger syndactyly 0.7784007081735015 2.0295081833134603 0.0424065563330402 1.0 0.2654156847379478 2 P15924 1 +Hypovolemic shock 0.7784007081735015 2.0295081833134603 0.0424065563330402 1.0 0.2654156847379478 2 P15924 1 +Abnormality of the extraocular muscles 0.7793392410901805 2.0271431762265197 0.0426477724153833 1.0 0.2661611314806627 3 P54098 1 +Abnormal morphology of the abdominal musculature 0.7851868495393354 2.022350016707555 0.043140204870776 1.0 0.2677926773571468 10 O00462,Q8WVQ1,Q8NCH0 3 +Heterophoria 0.7751549129536733 2.014934281687434 0.0439115354169419 1.0 0.2711288811296401 2 Q7Z392 1 +Abnormal size of pituitary gland 0.7766980925141385 2.0090408465337513 0.0445328020832032 1.0 0.2724255979680913 4 P31749 1 +Restrictive ventilatory defect 0.7828020632652974 2.006844688636646 0.0447662028207547 1.0 0.2733016533375776 12 P16278,P34059 2 +Clumsiness 0.7818353989222252 2.0013242836787417 0.0453574544303496 1.0 0.2756520526782849 19 P07602,P35670,Q13510,O75503,O14773 5 +Aplasia hypoplasia affecting the eye 0.3946316951083919 1.998196365436794 0.0456953754356195 1.0 0.2771184442516597 105 O15111,Q9BZK7,Q96N67,P98164,Q96ST3,Q6W2J9,O00192,P08069,P21359,Q9Y4P3,Q93074,Q9BXW9,Q9H3S7,P61586,Q8NFV4,Q7LGA3,Q9UBM7,Q15555,Q9Y297,O60333,O43505,O96028,O43709,Q15125,Q9UHX1,Q99519,Q15056,Q9H9S5,Q99643 29 +Abnormal intraocular pressure 0.776751771290806 1.9979851671232025 0.045718268245098 1.0 0.2771184442516597 6 Q8NCH0,P04439 2 +Progressive spastic quadriplegia 0.778633296661866 1.994953967701963 0.0460479006445266 1.0 0.2777467464674521 9 P17900,P07602 2 +Macular degeneration 0.7801172820500362 1.9942804585252631 0.046121413582044 1.0 0.2777467464674521 12 P04062,Q13510,P50897,P04439 4 +Infantile axial hypotonia 0.7789262085229759 1.993322668312106 0.0462261257358929 1.0 0.2780162711249486 10 P17900,O00754,P07602 3 +Abnormal pelvis bone morphology 0.7727816787783568 1.9912919962746216 0.0464487948718812 1.0 0.2788365135541618 4 Q93063 1 +Macular atrophy 0.7745425580907566 1.9878919636464627 0.0468236397402743 1.0 0.2788365135541618 6 P04062 1 +Orthostatic hypotension due to autonomic dysfunction 0.7763426197887734 1.9878408576894673 0.0468292934011618 1.0 0.2788365135541618 8 P07602 1 +Deviation of the 2nd finger 0.7732920358858761 1.9876770866245597 0.0468474146513262 1.0 0.2788365135541618 5 Q8WVQ1 1 +Thyroid adenoma 0.7743821726904329 1.9871588324160745 0.0469047983047556 1.0 0.2788365135541618 6 P31749 1 +Primitive reflex 0.775105324800786 1.9860842390911304 0.0470239710156037 1.0 0.2788365135541618 7 P17900 1 +Arterial thrombosis 0.7744249116901056 1.9829609746573205 0.0473717888504892 1.0 0.2801823786986204 7 P01889,O15460,P31749 3 +Secretory diarrhea 0.7674830333431498 1.9804034768945813 0.0476582095897657 1.0 0.2815173476022213 2 Q13277 1 +Macroorchidism 0.7737157353456316 1.9797046925614383 0.0477367209849552 1.0 0.2816223603145518 7 P21359,P31749 2 +Abnormal eyebrow morphology 0.3853760181521163 1.9787579423037571 0.0478432658102425 1.0 0.2818922789861433 165 Q69YQ0,Q10713,Q96N67,Q8N6M0,Q9H9B1,Q8IWS0,Q96ST3,P08069,Q96EK5,Q07954,P21359,Q14574,P04066,Q5KU26,P62857,P08236,Q9H3S7,Q13620,P54802,P51797,P15586,Q9NX24,Q7LGA3,Q13555,Q7Z3E5,O96028,Q15427,P63241,P48449,Q96PZ0,Q8N3R9,Q9UHX1,Q15125,Q9BUR4,P19022,O00754,O75844,O95831 38 +Overgrowth 0.7690773414356372 1.968465839586224 0.0490144628679589 1.0 0.2874046446867572 5 P21359,Q9H9B1 2 +Foam cells 0.7711262460605114 1.9678061541966496 0.0490903458229485 1.0 0.2874046446867572 7 Q99519,O15118,Q13510,P16278,P61916 5 +Bilateral coxa valga 0.7660619083370376 1.967170133008685 0.0491636000369544 1.0 0.2874046446867572 3 O00754 1 +Psychomotor deterioration 0.77320880916215 1.966744277090112 0.0492126995646506 1.0 0.2874046446867572 10 P06865,P07602 2 +Hamartomatous polyposis 0.7647926897915239 1.954992172381694 0.0505839941829564 1.0 0.2935644318227397 4 P31749 1 +Abnormal lower motor neuron morphology 0.7697917023549461 1.9540016601737709 0.0507010208527578 1.0 0.2938757921177977 9 Q9NUM4,Q13510,Q99720 3 +Abnormality of temperature regulation 0.3921838376811309 1.9519009146151212 0.0509499696863986 1.0 0.2949500742020356 111 Q9BZK7,P07602,Q9H0U9,Q04656,O15460,Q9NZ08,P38571,P06280,P28070,P51797,P01889,P11413,P10253,Q13144,Q5XKP0,Q9Y4U1,Q13510,P00403,Q9NQ11,P10644,P51798,P40763,P35270 23 +Hyperintensity of cerebral white matter on mri 0.7714898675841443 1.9501127720833396 0.0511626792827801 1.0 0.2954437656715463 18 P17900,P07602,O75503 3 +Abnormality of skin pigmentation 0.3918636108936311 1.9492890471042477 0.0512609158596355 1.0 0.2956428692053856 132 P07602,P04062,Q04656,Q96ST3,P51648,Q14739,O00192,P21359,Q8IZA0,Q93074,Q9H3S7,Q13423,Q13472,Q9NX24,P53634,Q8ND04,Q7LGA3,Q15555,P00403,O60333,Q15125,Q96PZ0,Q8N3R9,P10644,P31749,P51798,O60934,P29992,O75844,Q99643 30 +Constitutional symptom 0.3575272842053638 1.9407212692853228 0.0522920950868777 1.0 0.3008221899681147 251 Q9BZK7,P07602,Q04446,Q99643,O60313,P04062,Q04656,Q9UBS4,O15460,P42892,Q14739,P60866,O00192,Q9NZ08,P07384,Q07954,P21359,Q96HY6,Q9Y5K6,P06280,P28070,Q93074,Q14108,Q13423,P01889,Q70HW3,Q14126,P11413,Q07021,P04114,Q8TAA9,Q13510,P07686,O60333,O43709,Q99720,Q14203,Q9NQ11,P35670,Q96RR1,P19022,Q93063,O00754,P10644,P31749,P54098,P51798,Q15056,Q10471,P40763,P46020,P29992,O75844,Q9H9S5,Q4J6C6 55 +Decreased circulating acth level 0.7596995018239928 1.9383081605532804 0.0525856373947268 1.0 0.3008221899681147 3 P31749 1 +Narrow vertebral interpedicular distance 0.7590731508417092 1.9354625611021763 0.0529335586419033 1.0 0.3008221899681147 3 P10644 1 +Vertebral arch anomaly 0.7590731508417092 1.9354625611021763 0.0529335586419033 1.0 0.3008221899681147 3 P10644 1 +Impotence 0.7630256885280489 1.935117793568808 0.0529758424827209 1.0 0.3008221899681147 6 P07686 1 +Erectile dysfunction 0.7630256885280489 1.935117793568808 0.0529758424827209 1.0 0.3008221899681147 6 P07686 1 +Osteopetrosis 0.7588812831873281 1.9345907275101013 0.0530405387860055 1.0 0.3008221899681147 3 Q15392 1 +Regional abnormality of skin 0.3882265315593725 1.931244392425336 0.0534528365426394 1.0 0.3008221899681147 143 P07858,Q69YQ0,Q9BZK7,O15111,P56589,Q9H9B1,Q9H1A4,Q96ST3,Q14739,Q6W2J9,Q969X5,Q9Y4P3,Q93074,O43909,Q92917,Q9H3S7,Q8NFV4,Q9H2M9,Q9NX24,P53634,Q14126,Q8NCH0,Q7Z392,Q7LGA3,Q9UBM7,P23229,Q9Y263,Q9Y487,P40855,P41227,P15924,O75381,O96028,O43709,Q96PZ0,Q8N3R9,Q9UHX1,Q9BUR4,P09493,P31749,P14923,Q15056,P40763,Q99643 44 +Muscle fiber necrosis 0.7577179172445909 1.9293029452240695 0.0536932643365331 1.0 0.3008221899681147 3 Q96RR1 1 +Type ii transferrin isoform profile 0.7598936798582236 1.926483939028237 0.0540439753896053 1.0 0.3008221899681147 5 Q96MW5,Q15904,Q9Y2V7,O75787 4 +Osteoarthritis 0.7643629916844763 1.9202571676342104 0.0548254237793264 1.0 0.3008221899681147 12 Q8WVQ1,P35670,Q14108,P04062,P51798,P01889,O75844 7 +Branchial cyst 0.7539097078784336 1.9190273918387517 0.0549808673423695 1.0 0.3008221899681147 2 Q9UHX1 1 +Dilation of virchow robin spaces 0.7539097078784333 1.9190273918387517 0.0549808673423695 1.0 0.3008221899681147 2 P43034 1 +Mixed hearing impairment 0.7603739799938296 1.918258104905282 0.0550782918444963 1.0 0.3008221899681147 7 O00754 1 +Flared iliac wing 0.7576242643854433 1.916084249812889 0.0553543727402017 1.0 0.3019743839956652 5 O95831,P16278 2 +Loss of speech 0.7638517261244625 1.9153879008401264 0.0554430529968175 1.0 0.3020088205911468 20 P07602,O15118,P17900,O00754,P61916,P50897 6 +Facial erythema 0.7530244910002973 1.9150122162915344 0.0554909456854986 1.0 0.3020088205911468 2 Q9H1A4 1 +Bilateral external ear deformity 0.7533928118349562 1.9096213976770184 0.0561819780143997 1.0 0.3046968795938848 3 P15924 1 +Renal cortical microcysts 0.7515491295367334 1.908316924776448 0.0563502668118718 1.0 0.3052525551479552 2 Q8TD19 1 +Macular coloboma 0.7512540572440064 1.906977367655978 0.0565235183227179 1.0 0.3058337858371566 2 Q9Y4U1 1 +Abnormality of the abdominal organs 0.336796107213016 1.9004122768392513 0.0573790370570044 1.0 0.3086049632366964 373 Q8TD19,Q69YQ0,Q10713,P07602,P34059,Q04446,P56589,Q9UBS4,Q15392,Q14739,P60866,O00192,P11717,P04066,Q96HY6,Q9Y5K6,Q14108,P54802,P15586,Q9NX24,P53634,Q15904,Q96MW5,P10253,Q8NCH0,P55263,P10619,Q13510,Q7LG56,P07686,P61916,O43772,Q9UHX1,Q9HC07,Q99519,Q9BUR4,Q8NCM8,P35670,O75489,O00754,P31749,O15118,P04062,P16278,P38571,Q9Y6B6,P28070,P08236,P01889,Q07021,Q9UBM7,P04114,P31751,P00374,Q9UDY2,P10644,Q15056,P40763,Q9UN37,Q04656,Q9NZ08,Q5JPH6,O43909,Q9Y697,Q9Y4U1,P40855,O96028,P51798,O60934,Q7KZN9,O75787,Q8NB49,P11413,Q8N183,Q5XKP0,P00403,Q9ULC3,O43709,Q96RR1,P54098,O96000,P29992,Q99643 83 +Developmental regression 0.3883328262820447 1.8999856908465709 0.0574349974710521 1.0 0.3086049632366964 132 P07602,P56589,Q04656,P17900,Q96IX5,P16278,O75503,Q96ST3,O14773,P60866,Q9NZ08,P17480,Q5JPH6,P06280,P01889,Q96MW5,Q13144,Q9Y4U1,Q13510,P40855,P07686,O43709,Q99519,P54098,Q9GZZ9,Q15056,O95831 27 +Juvenile aseptic necrosis 0.7560034398144746 1.898053360241903 0.0576890531862659 1.0 0.3092533406066071 7 Q04656,Q9H173 2 +Asymmetry of the ears 0.7520810393082875 1.896976707849513 0.0578310122866094 1.0 0.3093302002287088 4 Q9UHX1,Q6W2J9 2 +Abdominal pain 0.5021347284719335 1.8969327904325857 0.0578368090572116 1.0 0.3093302002287088 90 Q9BZK7,P04062,Q04656,O15460,P42892,P60866,Q9P2R3,Q6W2J9,Q9NZ08,P21359,P06280,Q9Y5K6,Q9Y4P3,Q14108,Q13423,P01889,Q70HW3,P11413,Q7LG56,P07686,O60333,O43709,P54098,P52565,P10644,Q15056,P40763,P29992,Q99643 29 +Absent hand 0.7488934789023356 1.8962549443519805 0.0579263409396826 1.0 0.309452123199664 2 Q9Y297 1 +Spasticity 0.3546107701320929 1.887450142684694 0.0590998062462189 1.0 0.3144302854190604 327 Q8TD16,P07602,Q9UBX3,Q7KZN9,Q10713,O15118,P17900,P04062,Q8N6M0,Q15392,O75503,P16278,Q04656,P51648,O75787,Q9NVC6,O00584,Q9Y287,Q9H173,P07384,P49591,P17480,P04066,Q5KU26,Q5JPH6,Q9H490,O43909,P11117,Q9NQX3,O43464,Q04446,P56589,P50897,Q14671,Q8N183,O60313,O43292,Q13144,Q9Y487,Q5XKP0,Q13510,P40855,P07686,P61916,P23258,O43567,O43505,O43709,Q99720,Q14203,P39880,Q99519,Q9NQ11,Q9BV79,Q01105,Q9UBB6,P54098,O00754,Q15041,Q96N66,Q6IA86,Q9GZZ9,Q15056,P35270,Q9UN37,O95831 66 +Hemoptysis 0.7499520435462803 1.8872296864078113 0.0591294390522796 1.0 0.3144302854190604 4 Q9NZ08,P01889 2 +Abnormality of the spinocerebellar tracts 0.7482079241481246 1.8859802269374772 0.0592976192475698 1.0 0.3149634140331973 3 O00754 1 +Generalized osteosclerosis 0.7479105451704624 1.8846227419877293 0.0594807896654649 1.0 0.3155316165848578 3 Q15392 1 +Chronic axonal neuropathy 0.74623782826793 1.884179594239484 0.0595406867612142 1.0 0.3155316165848578 2 Q96MW5 1 +Generalized hyperkeratosis 0.7509275209695839 1.879400755284653 0.0601897932820572 1.0 0.3182440951526787 6 O75844,P04066,P31749 3 +Hypoplasia of the odontoid process 0.7525530481255213 1.8737101986140383 0.0609703794820886 1.0 0.3205438204744273 9 O43909,P08236,P16278,P34059 4 +Deep plantar creases 0.7464326612579206 1.864653830698808 0.0622299422046375 1.0 0.324224991014499 5 Q9BZK7 1 +Chronic fatigue 0.748939282377602 1.860846701923433 0.0627658282000858 1.0 0.325909059035153 8 P07602 1 +Large earlobe 0.7476965330713254 1.8595499362938217 0.0629492279860182 1.0 0.325909059035153 7 Q96N67,Q15392 2 +Angina pectoris 0.7450971270428925 1.8585006134456912 0.0630979563530746 1.0 0.325909059035153 5 P06280 1 +Mediastinal lymphadenopathy 0.7435461823682168 1.8513507493864692 0.0641191095237971 1.0 0.3283706572130043 5 P01889 1 +Psoriasiform dermatitis 0.7405730084304694 1.8510755603131344 0.0641586835098084 1.0 0.3283706572130043 3 P10321 1 +Menorrhagia 0.7385659486574192 1.8492209805729551 0.0644259104010593 1.0 0.3286549535565701 2 P40818 1 +Giant platelets 0.7385659486574175 1.849220980572946 0.0644259104010607 1.0 0.3286549535565701 2 Q14739 1 +Lipoma 0.7441212017454697 1.842937690858288 0.0653381084394262 1.0 0.330943886168149 7 Q8TAA9,P31749 2 +Cupped ear 0.7480427790219593 1.8389176437651469 0.0659273002670224 1.0 0.3333750178169934 14 P42892,Q15392 2 +Lower limb undergrowth 0.7375996734399426 1.837453005295128 0.0661430480230653 1.0 0.3341016488921068 3 Q93063 1 +Recurrent aspiration pneumonia 0.740739038248268 1.8322626452983268 0.0669122995673587 1.0 0.3376195137038549 6 Q13510 1 +Abnormality of carpal bone ossification 0.7416729870394466 1.8315486663996488 0.0670186907751189 1.0 0.3377887707872026 7 O43909,Q8WVQ1 2 +Multiple mitochondrial dna deletions 0.7361629156154952 1.8238940350404864 0.068168093645879 1.0 0.3420946431124905 4 Q96RR1,P54098 2 +Nocturia 0.7361629156154952 1.8238940350404864 0.068168093645879 1.0 0.3420946431124905 4 Q96RR1,P54098 2 +Aspiration 0.7417703101433084 1.816123026833619 0.069351502167049 1.0 0.3468184221051394 11 Q69YQ0,P06865,P17900,O15344,Q9NQX3,P42356 6 +Hypoplastic vertebral bodies 0.7371333851221924 1.8155345412688388 0.0694418027568137 1.0 0.3468184221051394 6 P10644,Q8TAA9,P16278 3 +Perseveration 0.7388438087315133 1.8136981092145328 0.0697242163482623 1.0 0.3468184221051394 8 P61916 1 +Phenotypic variability 0.3811760648111711 1.8134317091776668 0.0697652625741076 1.0 0.3468184221051394 108 Q8TD16,P07602,O60313,P17900,Q9BUF5,P33993,Q70HW3,Q14671,Q13510,P00403,P23258,Q6P4A7,O60333,Q15427,Q15125,P00374,Q8WVQ1,Q9BV79,P54098,Q9NUM4,P35270,Q6UWE0,Q9H9S5 23 +Abnormal prolactin level 0.7337861899531162 1.812941945412592 0.0698407758588508 1.0 0.3468184221051394 4 P31749 1 +Abnormality of the odontoid process 0.7401869182893189 1.8119728591634872 0.0699903902764926 1.0 0.3468184221051394 10 O43909,P08236,P16278,P34059 4 +Premature ventricular contraction 0.7372401167025797 1.81089893347176 0.0701564977215054 1.0 0.3468184221051394 7 P19022,P41227,P15924,Q14126,O43772 5 +Pedal edema 0.7389045137821074 1.8097354784428952 0.0703368178770869 1.0 0.3473395362045282 9 Q14108,O43567,P04062 3 +Fibrous tissue neoplasm 0.74249586699593 1.8090798203432883 0.0704386036287902 1.0 0.3474721330071282 18 P21359,P10644,P31749,Q15392,Q07954 5 +Pericarditis 0.7334280072220475 1.8045969804072737 0.07113777094587 1.0 0.3490662334869022 5 P01889,O15460 2 +Subcortical cerebral atrophy 0.730247757131512 1.796617753194562 0.0723963240323537 1.0 0.3534068143558148 4 O00754 1 +Limb dysmetria 0.7290286969487196 1.7909885551284457 0.0732951316081953 1.0 0.3562573640117419 4 P21359,P54098 2 +Abnormal cerebral artery morphology 0.7383119714410435 1.7894707106967682 0.0735390403777265 1.0 0.3565726624239775 16 P21359,P04114,P05067,P10253 4 +Cerebral inclusion bodies 0.7373730890377825 1.7876994178669368 0.0738245157147123 1.0 0.3567783803615268 14 P61916,O15118,P05067,Q9Y287 4 +Abnormal endocardium morphology 0.7379844617621063 1.7871973614722303 0.0739055956279075 1.0 0.3567783803615268 17 P06280,P04062,P10644,Q15056,P01889 5 +Small intestinal dysmotility 0.7255017709563076 1.781860028143852 0.0747720603017569 1.0 0.3589213702062599 3 P54098,Q7LG56 2 +Concave nasal ridge 0.7234777235957899 1.7725335602631842 0.076306029485671 1.0 0.3633098155058327 3 Q8WVQ1 1 +Gait disturbance 0.3485342971837491 1.7703690201184892 0.0766656870762521 1.0 0.3646141445872625 329 Q8TD16,P07602,Q10713,Q04446,O60313,O15118,P04062,P05067,Q8N6M0,P16278,O75503,Q04656,Q96N67,O14773,O75787,P60866,Q9H173,Q9NZ08,P07384,P17480,Q93074,O43909,Q14108,Q9NQX3,O43464,Q9H3S7,P01889,Q13472,Q8ND04,Q7LGA3,O43292,Q8IV08,Q13144,P13473,Q5XKP0,Q13510,P00403,O60333,Q7Z3E5,O43709,Q99720,Q96PZ0,Q14203,P41440,Q99519,Q8WVQ1,Q9NQ11,Q9BV79,P35670,Q96RR1,P54098,Q93063,O00754,Q15041,P31749,Q96N66,Q9GZZ9,Q15056,Q9NUM4,O14949,O75844,Q6UWE0,Q9H9S5,O95831,Q4J6C6 65 +Abnormal nasal bridge morphology 0.3438528375557648 1.7605917021591937 0.0783075340894836 1.0 0.3664097230806616 288 Q69YQ0,Q10713,P56589,P04062,Q96N67,Q8N6M0,Q15392,P16278,P98164,Q96ST3,P42892,Q14739,P60866,O00192,P08069,Q96EK5,P21359,Q5KU26,P62857,Q9H490,O43395,Q93074,O43909,Q9H3S7,Q13620,P15586,Q14671,Q7LGA3,Q9UBM7,Q15555,Q9UPY3,Q9Y487,P40855,Q9NX62,O43567,Q7Z3E5,Q5JRA6,O96028,Q15427,O43709,Q15125,Q96PZ0,Q9ULC3,Q99519,Q8WVQ1,Q01105,P19022,Q93063,O00754,P10644,P31749,Q15056,Q10471,P40763,O60934,O95831,Q4J6C6 57 +Abnormality of the pubic bone 0.7270583671691769 1.7584211093257882 0.0786758839767998 1.0 0.3677621713713918 8 Q8IZA0,Q04656 2 +Hypokinesia 0.7303941011505269 1.75408342571586 0.0794162132285847 1.0 0.3693096901825978 14 Q9NQ11,P13473,Q96RR1,P54098,P04062,Q9NQX3,Q9Y3D3,O95831 8 +Hepatic cysts 0.72096411626555 1.753683166812508 0.0794848114734165 1.0 0.3693096901825978 4 O43909 1 +Abnormal erythrocyte sedimentation rate 0.7252431251588163 1.749885195120774 0.0801381258320701 1.0 0.3716004894833092 8 P01889,P28070 2 +Abnormality of corneal stroma 0.7283164770244352 1.7463384386831329 0.0807521602906373 1.0 0.3731646988754809 13 P10619,P34059,P04062,Q13510,P16278,O43505 6 +Generalized lymphadenopathy 0.7155503098259068 1.7437048624785678 0.0812105670601472 1.0 0.3743274348488101 2 P50851 1 +Abnormal proportion of class switched memory b cells 0.7155503098259068 1.7437048624785678 0.0812105670601472 1.0 0.3743274348488101 2 P50851 1 +Angiofibromas 0.7194686910009783 1.7397930089818223 0.0818953704995029 1.0 0.3752458824171887 5 P31749 1 +Adenoma sebaceum 0.7194686910009783 1.7397930089818223 0.0818953704995029 1.0 0.3752458824171887 5 P31749 1 +Dysarthria 0.3686479128526831 1.737552023172146 0.0822897797800406 1.0 0.3760167014474125 168 P07602,Q7KZN9,O15118,P04062,O75503,P51648,O14773,Q9H173,P07384,Q14108,P15586,Q13472,Q14671,Q8N183,O43292,Q8IV08,Q13144,Q5XKP0,P07686,P61916,O43709,Q14203,P41440,Q9NQ11,Q9BV79,P35670,Q96RR1,P54098,O00754,Q15056,Q9NUM4,P35270 32 +Posterior pharyngeal cleft 0.7157615112160592 1.7369134788848906 0.0824024438884898 1.0 0.3760167014474125 3 P29372,O15344 2 +Abnormal b cell subset distribution 0.7157615112160585 1.7369134788848857 0.0824024438884907 1.0 0.3760167014474125 3 P50851,P17812 2 +Abnormal pupillary function 0.720331252888461 1.7318082610113714 0.0833077068100112 1.0 0.3768753481800552 7 O60333,P07602,P29992 3 +Chronic mucocutaneous candidiasis 0.7188264295125997 1.7302420984304576 0.0835870297086409 1.0 0.3768753481800552 6 P02786 1 +Micronodular cirrhosis 0.7199100648678052 1.7298318045810257 0.0836603302755873 1.0 0.3768753481800552 7 P11717,O75787 2 +Functional abnormality of the gastrointestinal tract 0.342064557869514 1.7223016486592737 0.0850148892208295 1.0 0.3812223116655267 287 Q69YQ0,P07602,O60313,Q9H0U9,P04062,P05067,O15118,Q9NVC6,Q04656,O15460,P42892,Q9H9B1,Q14739,P60866,P08183,O00192,Q9NZ08,Q9BUF5,P21359,Q8IZA0,P06280,Q93074,Q14108,Q9NQX3,P01889,P15586,Q13472,Q8N183,Q9UBM7,Q13510,P00403,P61916,O96028,O43709,Q99720,Q14203,P39880,Q9BQP7,Q99519,Q9NQ11,Q9BV79,Q01105,P35670,Q96RR1,P54098,Q93063,O00754,Q9GZZ9,Q15056,O60934,P40763,P29992,Q99643 53 +Spinal canal stenosis 0.7195845097494875 1.718596958370863 0.0856877859077227 1.0 0.3816851712335354 9 O43909,P10644,P31749 3 +Decreased cd4 cd8 ratio 0.7116292798111012 1.7177964369379606 0.085833751665735 1.0 0.3819684323167114 3 P17812,O00203 2 +Progressive visual loss 0.7213863037239209 1.7147128179429867 0.0863978923325381 1.0 0.3833751452114635 25 Q99519,P31749,O75503,P98164,O14773,Q9NWW5,P50897 7 +Barrel shaped chest 0.7136845506181058 1.7128426243728572 0.0867414960842234 1.0 0.3834939534923146 5 Q32P28,P04066 2 +Gastrointestinal stroma tumor 0.7128786158598324 1.7090830475934662 0.0874355672785847 1.0 0.3834939534923146 5 P21359 1 +Fetal akinesia sequence 0.7135104645923775 1.705366579747306 0.0881260772816916 1.0 0.3834939534923146 6 P04062 1 +Lymphoproliferative disorder 0.7120496160661574 1.7052147568050957 0.0881543788014673 1.0 0.3834939534923146 5 P50851,P17812,P33991,Q05655 4 +Recurrent infection of the gastrointestinal tract 0.7107172443396588 1.6989952596504976 0.0893200767857611 1.0 0.3849230446613145 5 O00754 1 +Abnormal hand bone ossification 0.7142453000815067 1.6980487047500634 0.0894985697578354 1.0 0.3849992149106481 8 O43909,Q8WVQ1 2 +Delayed gross motor development 0.3722553232060062 1.6947958401539798 0.0901141568989147 1.0 0.3864489324857598 108 Q10713,Q8N6M0,Q9H9B1,Q9UQR1,Q5KU26,O43909,Q9H3S7,P10253,Q8NCH0,Q7LGA3,O94886,Q7LBC6,Q99720,Q96PZ0,P48449,Q8N3R9,Q9UBB6,Q01105,P19022,P43034,Q96N66,P22570,P51798,Q10471,Q9H9S5 25 +Depletion of mitochondrial dna in muscle tissue 0.7105429340458123 1.691459966075062 0.090748987682834 1.0 0.3881015636699908 6 Q96RR1,P54098,Q9UBX3 3 +Ascites 0.7157252552854696 1.6889577661210342 0.0912275238209248 1.0 0.3881015636699908 26 Q99519,P08236,Q14108,O15118,P04062,Q13510,P61916,P38571 8 +Chronic diarrhea 0.7178756350648824 1.6888230163238689 0.0912533516608364 1.0 0.3881015636699908 21 Q13277,Q04656,Q13510,P07686,Q15904,P02786 6 +Progressive neurologic deterioration 0.7173522318225771 1.6874158835904298 0.0915234117676022 1.0 0.3881015636699908 22 P07602,P04062,P07686,P54802,Q9Y287 5 +Hypohidrosis 0.7138377382290357 1.6870255816251634 0.0915984330972383 1.0 0.3881015636699908 10 P06280 1 +Right ventricular cardiomyopathy 0.706606325120943 1.6869921028899073 0.0916048704648417 1.0 0.3881015636699908 4 Q14126,P15924 2 +Abnormality of urine homeostasis 0.3524124241327835 1.6865128934691047 0.091697053800777 1.0 0.3881015636699908 209 O15111,Q9BZK7,Q99643,P34059,P04062,Q9UNF1,O15460,P16278,P98164,P21359,P04066,P06280,P08236,Q14108,Q9Y697,Q9NQX3,O43464,P61457,Q13423,P54802,P01889,P15586,P11413,P10253,P23229,Q5XKP0,Q9Y4U1,P00403,O60333,Q5JRA6,O43709,O00462,Q99519,P35670,P54098,P10644,O00754,O96000,Q15056,P40763,P46020,P29992,Q9H9S5,Q4J6C6 44 +Pericardial effusion 0.7098547734768615 1.6825585157040248 0.0924605881507647 1.0 0.3905896440032002 7 Q14108 1 +Prominent antitragus 0.7022720566538846 1.6824163991573164 0.0924881235961858 1.0 0.3905896440032002 2 Q9H2M9 1 +Shock 0.7050487156776044 1.6797367590858203 0.0930085444008437 1.0 0.3914034465656524 4 P14923,P41227,P15924 3 +Undetectable visual evoked potentials 0.7016819120684612 1.6796858217648754 0.0930184598049059 1.0 0.3914034465656524 2 Q9H2M9 1 +Diabetes insipidus 0.7133077193333645 1.6770879165275907 0.093525291323735 1.0 0.3919372216536647 12 P01889,P31749,P06280 3 +Mask like facies 0.714896353219763 1.6769933603741152 0.0935437802111478 1.0 0.3919372216536647 15 Q9NQ11,P54098,Q04656,P04062,Q9GZZ9,O75787,Q14203 7 +Dilatation of the cerebral artery 0.7106200369071747 1.6677074198404884 0.0953738217672803 1.0 0.3979909977491359 11 P21359,P10644,P10253,Q9UBS4 4 +Trismus 0.7000754750218305 1.6565457342312444 0.0976113513758494 1.0 0.4014888130711885 4 P04062 1 +Protuberant abdomen 0.7029844479449046 1.655974900742358 0.0977269018113156 1.0 0.4014888130711885 6 P04062 1 +Delayed fine motor development 0.7056727674328451 1.6525766953197305 0.0984170442639373 1.0 0.4026225093274029 9 P19022,Q5KU26 2 +Premature osteoarthritis 0.6957804662142102 1.6523500369261557 0.0984632144872277 1.0 0.4026225093274029 2 Q96HY6 1 +Urinary retention 0.7021032860792953 1.6518322253415043 0.0985687573923417 1.0 0.4026989674258049 6 Q93063 1 +Recurrent skin infections 0.7096167698887569 1.6512448496237817 0.0986885885318631 1.0 0.4028336135759237 15 P53634,Q8NCH0,P40763,P02786 4 +Abnormality of circulating adrenocorticotropin level 0.7029961367650256 1.6502196982580994 0.0988980093595803 1.0 0.4033333943714813 7 P10644,P31749 2 +Anteverted ears 0.6968314920166726 1.649109268048684 0.0991252512570164 1.0 0.4039049121957691 3 Q6W2J9 1 +Abnormal systemic blood pressure 0.4356120053416368 1.64849793610228 0.0992505338726665 1.0 0.4040603385140956 96 Q10713,P07602,Q04446,P04062,Q04656,Q9UBS4,P42892,O00192,P38571,P21359,P06280,Q13423,P01889,P04114,Q8TAA9,P07686,P00403,O60333,O43709,Q14203,Q9UDY2,Q93063,P10644,Q15056,P29992,O75844,Q99643 27 +Supranuclear gaze palsy 0.7096348442469451 1.6474582281736108 0.0994638953832685 1.0 0.4045737569229965 21 Q9NQ11,P07602,O15118,P61916,Q99720 5 +Abnormal sharpey fiber morphology 0.7030949850750422 1.6452900981211962 0.0999100008461337 1.0 0.4057453713556087 8 P35670,Q04656,P01889 3 +Supravalvular aortic stenosis 0.7029881447612882 1.6447836248504282 0.1000144402543585 1.0 0.4057453713556087 8 Q9Y4P3,O43709,P04114,Q15056 4 +Glomerulopathy 0.7044853116564425 1.6382857680346783 0.1013620951272673 1.0 0.4090666660874681 11 Q9NZ08,Q14108,P01889,P06280 4 +Abnormal esophagus physiology 0.3449975322773919 1.6382841501721788 0.1013624324637698 1.0 0.4090666660874681 233 Q69YQ0,P07602,O60313,Q9H0U9,P04062,P05067,O15118,Q9NVC6,Q04656,Q9H9B1,Q14739,O00192,Q9BUF5,P21359,Q8IZA0,P06280,Q93074,Q14108,Q9NQX3,P01889,P15586,Q13472,Q8N183,Q9UBM7,Q13510,P61916,O96028,O43709,Q99720,Q14203,P39880,Q9BQP7,Q99519,Q9NQ11,Q9BV79,Q01105,P35670,Q96RR1,P54098,Q93063,Q9GZZ9,Q15056,P40763,Q99643 44 +Dysgenesis of the cerebellar vermis 0.6925346709943775 1.6372925467201278 0.1015693575158747 1.0 0.4095453137400965 2 Q10713 1 +Aplasia hypoplasia of the capital femoral epiphysis 0.6998212550761782 1.6352251319479347 0.1020018615504541 1.0 0.4100300740036403 7 Q7LGA3,Q8WVQ1 2 +Germinoma 0.6948603553536888 1.6321857684253125 0.1026403578920023 1.0 0.4106139661241391 4 P31749 1 +Joint swelling 0.6990982161035113 1.6318081625118552 0.1027199052628857 1.0 0.4106139661241391 7 Q13510 1 +Abnormal involuntary eye movements 0.3396191170973334 1.629862696588792 0.1031305192571341 1.0 0.4111700755260801 306 Q13277,Q10713,P07602,P56589,Q9BZK7,O60313,Q7KZN9,P17900,P04062,O15460,Q15392,O75503,Q8IWS0,O14773,O00584,Q9H173,P07384,Q5KU26,Q9H490,O43395,O43909,P51797,P01889,Q8N183,Q7LGA3,Q9UBM7,Q15555,Q8IV08,O43292,Q5XKP0,Q9Y4U1,Q13510,P40855,O60333,Q7Z3E5,O96028,O43709,Q99720,Q96PZ0,Q15125,P41440,Q99519,Q9NQ11,Q9BV79,Q96RR1,P54098,Q93063,O00754,O96000,P51798,Q15056,Q9NUM4,Q9GZZ9,Q10471,O95831 55 +Abnormal circulating phenylalanine concentration 0.6921603025539812 1.6273561454019465 0.1036614798550694 1.0 0.412536662398394 3 P61457 1 +Ulnar deviation of the wrist 0.6962861220069577 1.6244537480945096 0.1042790039627563 1.0 0.4139912169309086 6 P34059 1 +Calcification of the aorta 0.6961750104176041 1.6239303055453522 0.1043906837882684 1.0 0.4140800690557748 6 P04062 1 +Rieger anomaly 0.6928803636666052 1.62292645879805 0.1046051266891292 1.0 0.4143323467109136 4 P08069 1 +High forehead 0.4043117862600014 1.6227961421003998 0.1046329907264351 1.0 0.4143323467109136 100 Q9BZK7,P56589,Q04656,Q96ST3,Q14739,Q9H490,Q93074,Q9H3S7,Q13620,Q15904,Q7LGA3,Q8NC96,Q13555,P62258,Q9Y4U1,P40855,Q9NX62,O96028,O43709,Q96PZ0,Q8N3R9,Q99519,Q93063,Q9GZZ9,Q15056,Q10471 26 +Corneal opacity 0.6384252692200968 1.617495060847847 0.1057714609756113 1.0 0.4177702423713029 57 O15111,P34059,P04062,P16278,P51648,P04066,P06280,P08236,Q9UBM7,P04114,P10619,Q13510,P40855,O43505,O96028,Q9ULC3,O43709,Q99519,P35670,O00754,Q15056,O75844,Q9H9S5 23 +Abnormality of extrapyramidal motor function 0.5277745989437405 1.6130201904453318 0.1067401213515497 1.0 0.4205216165736077 81 P07602,Q04446,P17900,P05067,P04062,Q96IX5,P16278,O75787,P17480,Q5JPH6,P06865,Q9NQX3,O43464,P61457,Q9Y263,Q9Y4U1,P07686,Q9NWW5,O43709,Q99720,Q14203,Q9NQ11,Q96RR1,P54098,Q15056,Q9NUM4,O14949,P35270 28 +Impairment in personality functioning 0.3455049111861986 1.6077965395960392 0.1078797465804166 1.0 0.4241267291008281 217 Q69YQ0,P07602,Q7KZN9,P17900,P05067,P04062,O15460,O75503,Q9H9B1,P60866,O00192,P08069,P21359,P49591,P17480,P15311,P06280,Q93074,O43464,P01889,P50897,Q8N183,Q7LGA3,Q13144,Q8TAA9,P00403,O60333,Q9NWW5,O43709,Q96PZ0,Q14203,Q9NQ11,Q9UBB6,P35670,Q96RR1,P19022,P10644,O00754,Q96N66,P31749,P54098,Q9GZZ9,Q15056,Q9NUM4,P29992,Q99643 46 +Renovascular hypertension 0.696188934993589 1.6073945982460125 0.1079678342958154 1.0 0.4241267291008281 9 P21359,Q9Y4P3,O43709,Q15056 4 +Juvenile onset 0.6763438298223943 1.606940012678258 0.1080675278926817 1.0 0.4241267291008281 43 Q9NQ11,P34059,P06280,O15118,Q93063,Q13510,P16278,P54802,O14773,P40763,P38571 11 +Temperature instability 0.6937975901695119 1.6067344134236972 0.1081126410817103 1.0 0.4241267291008281 7 P07602 1 +Small epiphyses 0.6871310507673994 1.6038995451755471 0.1087361971057427 1.0 0.4249800749021183 3 Q14807,O95831 2 +Stooped posture 0.6864906455164757 1.6009100578638378 0.1093968415842709 1.0 0.425936421930502 3 Q9NQ11 1 +Abnormal central sensory function 0.6860831996428977 1.599007749564478 0.1098188806818079 1.0 0.425936421930502 3 P31749 1 +Abnormality of the palm 0.3671738524098103 1.597077000766566 0.1102485441873655 1.0 0.425936421930502 125 P07858,Q69YQ0,Q9BZK7,P56589,Q04656,Q9H9B1,Q96ST3,Q14739,Q9H173,P08069,Q93074,O43909,Q13620,Q9NX24,Q14126,P53634,Q8NCH0,Q15555,Q13555,Q9Y263,Q9Y487,P40855,O96028,Q9UHX1,Q9BUR4,P09493,P10644,P31749,O95831,Q99643 30 +Sensory ataxia 0.6888815273572186 1.5966693631661673 0.1103394283014913 1.0 0.425936421930502 5 Q96RR1,P54802 2 +Furrowed tongue 0.6913173361511636 1.5949878753629383 0.1107149471314024 1.0 0.425936421930502 7 O15078,Q9H2M9,P31749,Q99643 4 +Aplasia hypoplasia affecting bones of the axial skeleton 0.3387496968377912 1.5931306680370363 0.1111308807133415 1.0 0.4269377745383303 253 Q8TD19,O15111,Q69YQ0,Q8TD16,P56589,P34059,P51571,P04062,Q04656,Q15392,P16278,Q96ST3,Q14739,P60866,O75787,Q6W2J9,O00192,P08069,Q969X5,P42356,P21359,P46783,P04066,Q96HY6,P62857,Q9Y4P3,P08236,Q93074,Q9BXW9,Q9H3S7,O43909,Q92917,Q8NFV4,Q9H2M9,Q8ND04,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,Q9Y263,P40855,Q9NX62,O96028,Q9ULC3,Q15427,P63241,Q96PZ0,Q15125,Q8N3R9,Q9UHX1,O43709,Q8WVQ1,Q8NCM8,Q93063,P10644,P31749,Q15056,O60934,O75844,Q9H9S5,O95831 63 +Gingival bleeding 0.693587943267852 1.5902204222410443 0.1117851287173365 1.0 0.4290957300184517 10 Q14108,P04062,P40763,P10644 4 +Accessory spleen 0.689840843326893 1.587991004848286 0.1122883731744543 1.0 0.4294914735969622 7 Q15904 1 +Decreased urine output 0.6816169961640499 1.586530984592319 0.1126189091939404 1.0 0.4294914735969622 2 O43772 1 +Oliguria 0.6816169961640499 1.586530984592319 0.1126189091939404 1.0 0.4294914735969622 2 O43772 1 +Laryngeal stenosis 0.6849255344629368 1.5856688356076007 0.1128144521977787 1.0 0.4294914735969622 4 O43909 1 +Retinal dysplasia 0.6891233936155879 1.584590013114471 0.1130595154907669 1.0 0.4295429464804072 7 O43505,Q9H9S5 2 +Coronal craniosynostosis 0.6886364131154681 1.5822811253040288 0.1135854076133031 1.0 0.4306586550309785 7 Q9NX62 1 +Abnormal pericardium morphology 0.693486842366978 1.581475438756108 0.1137693704949198 1.0 0.431003734464823 12 Q14108,P04062,O15460,P01889 4 +Abnormal retinal artery morphology 0.6942630066630008 1.5754335698911486 0.1151564007905672 1.0 0.4334255117417697 25 Q99519,P10619,P07602,P06865,P17900,Q13510,P16278,P07686,Q15056 9 +Quadriceps muscle weakness 0.6869361447105855 1.574217178331356 0.1154372492619759 1.0 0.4341301904523783 7 O95140,Q96RR1,P54098,Q7LG56,Q13049 5 +Decreased muscle mass 0.6947077149019188 1.5720931414106192 0.1159289518859474 1.0 0.4347364872763917 20 P04066,Q8TAA9,Q9Y487,P54098,P31749,O96028,Q8NCH0 7 +Abnormal posterior segment imaging 0.6820064837674191 1.5719747445111127 0.1159564084653164 1.0 0.4347364872763917 4 P04439 1 +Conspicuously happy disposition 0.6783712009442135 1.571407351560068 0.1160880594533453 1.0 0.4347364872763917 2 Q96ST3 1 +Vascular calcification 0.6862414975422827 1.570921496740826 0.1162008846502997 1.0 0.4347364872763917 7 P04062 1 +Macroglossia 0.6827538536315815 1.570919199784668 0.1162014182539807 1.0 0.4347364872763917 36 Q7LGA3,P04066,Q10713,Q9C0B1,O00754,Q9H9S5,P16278,Q9H9B1,P07686,P31749,Q15056,O43709,P10253,Q99643 14 +Orthostatic hypotension 0.6929129460701703 1.5694917951571024 0.1165333897958944 1.0 0.4348231111879354 15 P07686,P04062,P07602 3 +Cerebral cortical atrophy 0.3626462563801869 1.569380842682533 0.1165592251901237 1.0 0.4348231111879354 107 Q69YQ0,Q8TD16,P04062,P05067,Q8N6M0,Q96N67,O75503,Q9H9B1,P17480,Q5KU26,Q92917,Q9H3S7,Q7LGA3,P62258,Q9Y263,Q9Y4U1,P00403,O43709,Q96PZ0,Q8N3R9,Q9NQ11,Q96RR1,O00754,Q15056,Q9NUM4,Q9H9S5 26 +Limb ataxia 0.692073884910379 1.566691156535191 0.1171868988810362 1.0 0.4358731577754963 26 P41440,Q8IV08,P54098,Q14108,P04062,O00754,Q9GZZ9,O14773,Q9H173,P07384 10 +Breech presentation 0.6876593445032415 1.5666458749585064 0.1171974886017055 1.0 0.4358731577754963 9 Q9UBM7,O60313,Q9H3S7,Q7LBC6,Q969X5 5 +Focal white matter lesions 0.6865303722628111 1.566563744705187 0.1172166978102315 1.0 0.4358731577754963 8 Q96RR1,P54098,O00584 3 +Abnormal sputum 0.6818422414520394 1.5635328604300942 0.1179273128180762 1.0 0.4374631596299355 5 Q9NZ08,P01889 2 +Myocardial fibrosis 0.679971158229435 1.5624196290518304 0.1181891658940523 1.0 0.4380840625505362 4 P13473 1 +Spinal deformities 0.6811071388918504 1.552782619260333 0.1204750763816857 1.0 0.4436878593466288 6 Q9BQP7,Q93063 2 +Abnormality of head blood vessel 0.6871821966785997 1.5516585043875375 0.1207439564965238 1.0 0.4440045410581926 29 P21359,Q99519,P04114,P10619,P07602,P06865,P17900,Q13510,P16278,P07686,Q15056 11 +Corneal erosion 0.6759509967929114 1.5435303856543945 0.122702140868488 1.0 0.449423244239478 4 Q96EK5,P01889 2 +Dilatation of the ventricular cavity 0.6721746827972876 1.5424960601533562 0.1229530946059695 1.0 0.4499279947714698 2 P27635 1 +Abnormal myeloid leukocyte morphology 0.3599474148160363 1.5407302054410403 0.123382462197618 1.0 0.4508467117496886 105 Q99519,Q9BZK7,P62857,O43909,O15118,P09493,Q13510,P10644,P16278,P61916,P01889,P40763,Q14126,P38571,P02786 15 +Hamartoma of tongue 0.6727810558737075 1.5367775420788328 0.1243477947881186 1.0 0.4532310531130445 3 Q8NCM8 1 +Impaired mastication 0.6773996830229931 1.5352295078645573 0.1247274625368715 1.0 0.4532310531130445 6 P01889 1 +Bile duct proliferation 0.6757822122576542 1.534953005347261 0.124795372040761 1.0 0.4532310531130445 5 P54098,Q5XKP0 2 +Calf muscle pseudohypertrophy 0.6723730814639781 1.5348652973272483 0.1248169193067409 1.0 0.4532310531130445 3 Q13049,Q9H9S5 2 +Visual hallucinations 0.6783362758132869 1.5333706776436116 0.1251845492468994 1.0 0.4542102933160194 7 Q9NWW5,Q9NQ11 2 +Abnormal brain positron emission tomography 0.6745000350511577 1.528900085913379 0.1262892149590042 1.0 0.4553373561417214 5 P31749 1 +Abnormal form of the vertebral bodies 0.4448335011223088 1.527240293721554 0.1267012701239802 1.0 0.4553373561417214 93 Q10713,P34059,Q04656,P16278,Q14739,P21359,P04066,O43909,P08236,P54802,P15586,Q9UBM7,Q8TAA9,Q32P28,Q7Z3E5,Q5JRA6,O96028,Q15427,O43709,Q15125,Q99519,Q8WVQ1,P10644,O00754,P31749,P51798,Q15056,O95831 28 +Moderately reduced visual acuity 0.6706021251475677 1.5265621308571442 0.1268699297250601 1.0 0.4553373561417214 3 O60313,P63000 2 +Mitral stenosis 0.6721713173970718 1.525752259615612 0.1270715741886405 1.0 0.4557083445574063 4 P04062,Q9UQR1 2 +Abdominal obesity 0.6700118063754318 1.5237935516970296 0.127560290881741 1.0 0.4560659217611496 3 Q13620,P40818 2 +Red eye 0.6842185201206724 1.5224362905922484 0.1278997974425522 1.0 0.456569806012201 17 P01889,P02786,P28070 3 +Abnormal superior cerebellar peduncle morphology 0.6696946848617886 1.5223060851175612 0.1279324040649461 1.0 0.456569806012201 3 Q10713 1 +Increased intracranial pressure 0.6843320561516774 1.5215029332058891 0.1281336757961177 1.0 0.4566916638482692 18 P07602,P10644,P31749,P01889,P29992,Q9NZ08,Q99643 7 +Severe short limb dwarfism 0.6693721275169155 1.5207929965734075 0.1283117924733159 1.0 0.4567805535589551 3 Q14739 1 +Abnormality of the peripheral nervous system 0.3599511382575348 1.5198273538114142 0.1285543723727038 1.0 0.4571369821259414 111 Q10713,P07602,Q04446,O60313,Q9H0U9,P04062,Q04656,P42892,Q96EK5,P06280,O43464,Q9UBM7,P07686,O60333,Q7Z3E5,Q15427,Q15125,Q99720,P41440,Q99519,Q96RR1,P54098,Q6UWE0,O95831 24 +Nasal regurgitation 0.6681401298658738 1.5150126496767973 0.1297692006987834 1.0 0.4603976921501596 3 Q13472 1 +Pelvic kidney 0.6778317812868113 1.5144876379836711 0.1299022068262143 1.0 0.4605172271048592 10 Q9UHX1,Q9Y4P3,Q9BXW9,Q15056,Q8NFV4,O43709 6 +Status epilepticus with prominent motor symptoms 0.6685821797348465 1.5088541441534673 0.1313360605463942 1.0 0.4641808786231936 4 Q96RR1,Q13510 2 +Disseminated intravascular coagulation 0.6752475963222648 1.507175813371641 0.1317655981136547 1.0 0.4642834942652105 9 P40763,P38571,P10644,Q9BZK7 4 +Osteomalacia 0.6718346036572258 1.5024275314115088 0.1329867305547205 1.0 0.4669078085575856 7 P35670 1 +Hyperorality 0.6671957301792295 1.5023224695568875 0.1330138484159091 1.0 0.4669078085575856 4 Q9NUM4 1 +Agnosia 0.6751680571077433 1.501652793011893 0.1331868014495349 1.0 0.4671612695321435 10 Q9NUM4,O75787,P05067 3 +Gangrene 0.6776692382008241 1.5009315844343634 0.1333732579445623 1.0 0.4674616758041841 13 Q9BZK7,P10644,O15460,P01889,P40763 5 +Shoulder girdle muscle weakness 0.6785248473015866 1.4962278743362023 0.1345942830704114 1.0 0.4690457117013455 16 Q8TD16,P07602,Q96RR1,P54098,Q9H9S5 5 +Ascending tubular aorta aneurysm 0.6666846510583608 1.4919621143937212 0.1357090774798901 1.0 0.4710202037980918 5 Q93074,P01889 2 +Aplasia hypoplasia involving the vertebral column 0.6781718036966595 1.4907415365097751 0.1360293663445446 1.0 0.4717787372772278 18 Q8TAA9,P04066,P34059,O43909,P08236,P10644,P16278,Q14739,O95831 9 +Neuronal loss in central nervous system 0.6737383257181414 1.49000111053867 0.136223943932142 1.0 0.4718428331908367 11 O15118,P07602 2 +Agyria 0.6662481241657185 1.4898968520238978 0.1362513594225858 1.0 0.4718428331908367 5 P23258,P43034,Q9H9S5 3 +Inguinal hernia 0.5020849924321954 1.4879183082978191 0.1367724387634603 1.0 0.4729409385131735 83 Q69YQ0,Q10713,P34059,Q04656,P16278,Q9H9B1,Q96ST3,O00192,Q9Y4P3,P08236,Q93074,Q9NQX3,Q13620,Q8NFV4,Q8WYQ5,Q8NCH0,Q15555,P60953,P62258,Q9Y487,Q32P28,P41227,O43567,Q7LBC6,O43709,Q9UHX1,Q99519,O00754,P31153,P43034,O94979,Q15056 32 +Bowel diverticulosis 0.6718755711712343 1.485776726811322 0.1373381880118287 1.0 0.4738840331582407 10 Q9Y4P3,O43709,Q15056,P31749 4 +Abnormality of the liver 0.3340165444805393 1.4799870891206104 0.1388766922338136 1.0 0.47525551430863 320 Q8TD19,Q69YQ0,Q10713,P07602,P34059,Q7KZN9,Q04446,O15118,P04062,Q04656,P56589,P16278,Q9UBS4,O75787,Q14739,P60866,O00192,P38571,P11717,Q9Y6B6,P04066,Q5JPH6,Q96HY6,P28070,O43909,P08236,Q14108,Q9Y697,P54802,P15586,Q8NB49,Q9NX24,P53634,Q15904,P11413,P10253,Q07021,Q8N183,Q96MW5,Q9UBM7,P55263,P04114,P10619,P31751,Q5XKP0,Q9Y4U1,Q13510,P40855,P07686,Q7LG56,P61916,O96028,O43709,O43772,P00374,Q9HC07,Q99519,Q9UDY2,Q9BUR4,Q8NCM8,P35670,Q96RR1,P54098,P10644,O00754,O96000,P51798,Q15056,P40763,Q9UN37,Q99643 71 +Heterotaxy 0.6637285985971157 1.477972521860171 0.1394151332235076 1.0 0.476044162560681 5 Q7LBC6 1 +Abnormality iris morphology 0.4711315990990533 1.47290481433293 0.140776703741561 1.0 0.4799864523894254 88 Q9NR77,Q10713,P56589,P98164,Q96ST3,Q6W2J9,P08069,Q96EK5,P21359,Q9Y4P3,Q9BXW9,P61586,Q8NFV4,Q7Z392,Q7LGA3,Q9UBM7,Q9Y467,Q9Y297,P40855,P41227,O60333,O75381,Q7Z3E5,O43505,O96028,O43709,Q9UHX1,O15078,P10644,P31153,P31749,Q15056,P29992,Q9H9S5,Q99643 35 +Aplasia hypoplasia of metatarsal bones 0.667793078141286 1.471367688912882 0.1411917066511867 1.0 0.4810477176646238 9 Q8WVQ1,Q9H173 2 +Increased circulating acth level 0.6586763905408757 1.4705518979562002 0.1414123407050711 1.0 0.4814456856456791 3 P40818 1 +Abnormality of the distal phalanges of the toes 0.6635234292794814 1.4693835266224151 0.1417287929076325 1.0 0.4821690482118063 6 Q7LGA3 1 +Abnormal external genitalia 0.3312557431592126 1.468816540068305 0.1418825565753159 1.0 0.482338280674296 303 Q69YQ0,Q10713,P56589,Q15392,Q96ST3,P42892,P60866,O00192,Q5KU26,Q9H3S7,Q13620,Q9NX24,Q8NCH0,Q7LGA3,O94886,O43505,P63241,P48449,Q8N3R9,Q9UHX1,Q9BUR4,Q8NCM8,Q93063,P43034,P31749,P22570,Q9H0U9,P51571,Q8N6M0,Q9H1A4,Q9H173,Q6W2J9,P21359,P46783,Q9Y4P3,Q93074,Q9BXW9,P50213,P01889,Q8NFV4,Q9H2M9,Q8WYQ5,Q9UBM7,P60953,P61313,P41227,O75381,Q96PZ0,O15078,O15344,P10644,O43172,Q15056,Q9BZK7,Q9UBX3,Q9NZ08,Q96EK5,P62857,O43395,Q13423,Q8ND04,P23229,Q8TAA9,P62258,Q9Y487,P40855,Q7LBC6,O96028,Q15125,P19022,O15111,Q9H9B1,Q8IWS0,O75787,Q9C0B1,Q15555,Q9UPY3,Q9ULC3,O43709,P54098,O75844,Q9H9S5,Q99643 83 +Abnormal morphology of myocardial trabeculae 0.6617118303572243 1.4684226478373854 0.1419894534140335 1.0 0.4823480552973433 5 Q9Y4J8,P14923 2 +Abnormal branching pattern of the aortic arch 0.6562407789908449 1.4679373921208296 0.1421212300550429 1.0 0.4824422721561011 2 Q8WYQ5 1 +Acetabular dysplasia 0.6665768271637874 1.4655194819796444 0.1427792410506327 1.0 0.4836138354651455 9 O43909,P08236,P16278 3 +Abnormality of the nasal alae 0.3504607297117565 1.464834228811744 0.1429661507144899 1.0 0.4838523694425564 171 Q9BZK7,P04062,Q96N67,Q15392,P16278,P98164,Q9H9B1,P08069,P10586,P21359,Q5KU26,Q9C0B1,O43395,Q93074,O43909,P15586,Q7LGA3,Q9UBM7,Q15555,P62258,Q9Y487,P40855,Q7LBC6,Q8WVQ1,Q93063,P10644,P31749,O95831 28 +Abnormal hair morphology 0.3236932269372042 1.4644964351891092 0.1430583563738936 1.0 0.4838523694425564 350 Q8TD19,Q69YQ0,Q9BZK7,Q10713,Q7KZN9,Q04656,O15460,Q8N6M0,P16278,Q96N67,P98164,Q9H9B1,Q8IWS0,Q96ST3,P60866,P08069,Q96EK5,Q07954,P21359,Q14574,P04066,Q5KU26,P62857,Q9H490,Q93074,P08236,Q9H3S7,Q13620,P61586,P54802,P01889,P51797,P15586,Q9NX24,P53634,Q8N183,Q7LGA3,Q9UBM7,Q15555,Q13555,Q9Y487,Q9Y263,P40855,P00403,Q7Z3E5,O96028,Q15427,Q15125,P48449,Q96PZ0,P63241,Q8N3R9,Q9UHX1,Q99519,Q8WVQ1,Q9BUR4,O75489,P19022,Q93063,O00754,P10644,P31749,P51798,O60934,P40763,P29992,Q13126,O75844,O95831,Q4J6C6 70 +Anal stenosis 0.6607043424117853 1.463650339691098 0.1432895106789107 1.0 0.4839282308944712 5 Q93074,O60934 2 +Sensory axonal neuropathy 0.6710139834955104 1.459023484618929 0.1445586440239346 1.0 0.4875043144283524 16 Q8IV08,Q9NQ11,Q96RR1,O95831,P07384 5 +Abnormality of the curvature of the vertebral column 0.33282565749006 1.4553473578683245 0.1455731221192522 1.0 0.4898567251574546 332 Q8TD19,Q8TD16,Q9BZK7,P34059,Q10713,P04062,Q04656,Q8N6M0,P16278,Q8IWS0,Q96ST3,P51648,O75787,Q14739,Q9H173,O00192,P07384,Q969X5,P21359,P17480,P04066,Q5KU26,Q9H490,Q96HY6,Q93074,P08236,Q14108,O43909,Q9H3S7,Q13620,P01889,Q9NX24,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q8TAA9,Q9Y487,Q9Y263,Q32P28,Q13510,Q7LG56,O43567,Q7Z3E5,Q5JRA6,O96028,Q9ULC3,Q15427,Q99720,P48449,Q96PZ0,Q15125,O43709,Q9BQP7,Q99519,Q8WVQ1,P39880,Q8N3R9,Q01105,Q9UHX1,Q9HC07,Q9BUR4,Q93063,O00754,P10644,P31749,Q8NCM8,O75489,Q15056,P43034,P40763,O75844,Q9H9S5,O95831,Q99643 75 +Emg chronic denervation signs 0.6668206548454177 1.4479062623922685 0.1476432680096686 1.0 0.4953848290599374 13 P07602 1 +Positive romberg sign 0.6631934036516163 1.443854456880016 0.148779919866584 1.0 0.4976869930497224 10 Q96RR1,P41440,Q8IV08 3 +Visual loss 0.6208764335645901 1.4422742823581012 0.1492250122880851 1.0 0.4981687415261706 54 P21359,Q99519,P07602,P31749,O75503,P98164,O14773,P01889,P50897,Q9NWW5,P48449,P04439 12 +Chondrocalcinosis 0.6574121783840042 1.4403170201903908 0.1497777282092776 1.0 0.4985781232637618 6 P35670,Q04656 2 +Abnormal intestine morphology 0.3386005806621535 1.4361432047062657 0.150961596271641 1.0 0.5014390558106014 208 Q13277,Q10713,P56589,Q04656,Q15392,P98164,Q96ST3,P42892,Q14739,P60866,P08183,P38571,Q9NZ08,Q96EK5,Q9Y6B6,P62857,P06280,Q93074,P01889,Q8NCH0,Q9UBM7,P23229,Q8TAA9,Q9UPY3,P40855,P00403,Q7LBC6,Q7Z3E5,O96028,Q15427,O43709,Q9UDY2,Q96RR1,P54098,Q93063,P10644,P31749,Q15056,P40763,O75844,Q99643 41 +Hyperreflexia in upper limbs 0.6598087242638093 1.4329478414745644 0.1518727437008158 1.0 0.5026889138996603 9 Q9NQ11 1 +Aortic valve stenosis 0.6608801019020669 1.4326714339142752 0.1519517567774673 1.0 0.5026889138996603 10 Q8TD19,P04062,P16278,Q9H9B1,O75844,Q15125 6 +Phonophobia 0.6570290162777056 1.4317857726506995 0.1522051402016655 1.0 0.5026889138996603 7 Q9Y4P3,O43709,Q15056 3 +Overfriendliness 0.6570290162777056 1.4317857726506995 0.1522051402016655 1.0 0.5026889138996603 7 Q9Y4P3,O43709,Q15056 3 +Nystagmus induced head nodding 0.6570290162777056 1.4317857726506995 0.1522051402016655 1.0 0.5026889138996603 7 Q9Y4P3,O43709,Q15056 3 +Flat cornea 0.6570290162777056 1.4317857726506995 0.1522051402016655 1.0 0.5026889138996603 7 Q9Y4P3,O43709,Q15056 3 +Dilated third ventricle 0.6506224453805673 1.4240834423136453 0.1544223188716731 1.0 0.5078485705962809 4 O75787,P26358 2 +Tracheal stenosis 0.6554127123378695 1.4240605050628157 0.1544289579982618 1.0 0.5078485705962809 7 Q9UBM7,O43909,Q15125 3 +Abnormal sella turcica morphology 0.6562943621902578 1.4219473540167322 0.155041534751243 1.0 0.5084353583037582 8 O00754,P16278 2 +Myositis 0.657120321032975 1.4199974369710742 0.1556084272246023 1.0 0.5091071661974312 9 P01889,P28070 2 +Redundant neck skin 0.6522125718253394 1.4155580193957846 0.1569049499118229 1.0 0.5109197631874245 6 Q9Y487,O96000 2 +Unusual fungal infection 0.6561238552302675 1.4151956439461155 0.157011141372025 1.0 0.5109197631874245 9 P02786 1 +Tremor 0.3439286388889579 1.4126212764810822 0.1577671097102142 1.0 0.5126601876147606 181 Q10713,P07602,P04062,O75503,O14773,O75787,Q9Y287,P21359,Q14108,O43464,P61457,O43292,Q9Y4U1,Q13510,O60333,Q6P4A7,Q7Z3E5,O43709,Q99720,Q14203,P41440,Q99519,Q9NQ11,P35670,Q96RR1,P54098,P31749,P51798,Q15056,Q9NUM4,Q9GZZ9,P35270,O95831,Q99643 34 +Bone fracture 0.6528413345431293 1.4117655057151954 0.1580190182625716 1.0 0.5128029498636191 7 P51798,Q93063 2 +Anisocoria 0.649605212583945 1.4110094118852012 0.1582418388426065 1.0 0.5128653589539697 5 Q9NR77,Q96ST3 2 +Oroticaciduria 0.6438477426969648 1.4097618388669662 0.1586100182218253 1.0 0.5128833016001458 2 P11172 1 +Small anterior fontanelle 0.643847742696964 1.4097618388669624 0.1586100182218264 1.0 0.5128833016001458 2 P26640 1 +Abnormality of the nail 0.3532490250315277 1.4081661798098029 0.1590818682008075 1.0 0.5140095934503199 119 P10321,Q96ST3,P42892,Q14574,P04066,Q9C0B1,P53634,P23229,Q13555,Q9Y487,O43567,O96028,O43709,Q15125,Q93063,P10644,P31749,Q15056,P40763,P29992,O75844 21 +Abnormal rib cage morphology 0.4873953263349906 1.406771198987553 0.1594952454522371 1.0 0.5146690697021737 84 Q8TD19,P34059,Q04656,P16278,Q14739,P08069,P04066,Q93074,P08236,Q92917,P54802,P15586,Q9UBM7,Q8TAA9,Q32P28,O96028,Q15427,Q8WVQ1,Q93063,O00754,P31749,P51798,O75844,O95831 24 +Soft skin 0.6541229081918261 1.4055507877850792 0.1598575580867964 1.0 0.515304159356885 9 Q04656,O00754 2 +Multifactorial inheritance 0.6589156170343999 1.4053597929456518 0.159914316436178 1.0 0.515304159356885 14 P42892,P10321,P01889 3 +Abnormal blood chloride concentration 0.6443990866879142 1.403302982964293 0.1605265090759891 1.0 0.5165589330918539 3 Q9UNF1 1 +Abnormality on pulmonary function testing 0.6611385698755802 1.4026757168808526 0.1607135616891992 1.0 0.5168022091212323 20 P31749,P16278,P34059 3 +Abnormal metatarsal morphology 0.6602272045175045 1.4007351527289067 0.1612932866267864 1.0 0.5179609508359008 26 Q9UBM7,Q8WVQ1,P08236,P10644,O96028,Q15392,P31749,Q9ULC3,Q9H173,O43505 10 +Abnormal conus terminalis morphology 0.6518481113812029 1.4006005968738344 0.1613335423744399 1.0 0.5179609508359008 8 Q93063 1 +Coxa valga 0.659090857016278 1.3947912841657837 0.1630787879667843 1.0 0.5201834738873485 26 P04066,Q8WVQ1,P34059,Q04656,Q93063,O00754,P16278,Q9H173 8 +Anophthalmia 0.6541153873511216 1.394769997547543 0.1630852090109877 1.0 0.5201834738873485 11 Q96N67,P41227,Q6W2J9,O43505,Q9H9S5 5 +Bladder diverticulum 0.653029665171786 1.3946837427377663 0.1631112294656469 1.0 0.5201834738873485 10 Q9Y4P3,Q04656,O43709,Q15056 4 +Axillary pterygium 0.6438690348394482 1.39212714624275 0.1638838991928248 1.0 0.521714630424472 4 P23229 1 +Hemifacial spasm 0.6419303317597833 1.3916563887422075 0.1640264745112447 1.0 0.521714630424472 3 P31749 1 +Clubbing of fingers 0.6419198975736172 1.391607154278453 0.1640413912354712 1.0 0.521714630424472 3 P15924 1 +Arterial stenosis 0.6581574852687102 1.390500561048598 0.1643769290597485 1.0 0.5218012342754871 18 P21359,P04114,Q9Y4P3,Q04656,P31153,O60333,Q15056,P01889,O43709 9 +Ambiguous genitalia male 0.6416764340854826 1.3904583303902958 0.1643897443442503 1.0 0.5218012342754871 3 Q15392 1 +Abnormality of the bladder 0.3522494217230172 1.3881827910723634 0.1650813911326589 1.0 0.5218012342754871 123 Q04446,P07602,P56589,P04062,Q04656,Q9H9B1,P07384,Q93074,P51797,P01889,Q8NCH0,P23229,Q8TAA9,P07686,O43709,Q99720,Q9NQ11,Q96RR1,P54098,Q93063,P31749,Q15056,Q10471,O60934 24 +Long nose 0.6488587430484628 1.3862391402046548 0.1656738935988526 1.0 0.5233173328459672 8 Q93074,O60934,O43909 3 +Abnormality of the lens 0.3322977096466417 1.385494883615477 0.1659011958954348 1.0 0.5236785877243917 226 Q8TD19,Q10713,P56589,O60313,Q9H9B1,Q9H1A4,P98164,Q8IWS0,P60866,Q9Y287,Q9H173,Q6W2J9,O00192,Q9NZ08,P26358,P46783,P62857,P06280,O43395,Q9Y4P3,Q9BXW9,P50213,O43464,P61586,P00390,P01889,Q8NFV4,Q9H2M9,Q9NX24,Q8ND04,Q7Z392,Q7LGA3,Q9UBM7,Q15555,Q9Y467,Q7LG56,P40855,P61313,P00403,P41227,P23258,O43567,O60333,O75381,O43505,O43709,Q15125,P48449,P04439,Q99519,Q9BUR4,Q13126,Q8NCM8,Q96RR1,O15078,P54098,O00754,O43172,P31749,P22570,O94979,Q15056,Q9GZZ9,P29992,Q9UN37,Q99797,Q9H9S5,Q99643 68 +Mortality aging 0.3509663170375853 1.378251492963101 0.1681256539176847 1.0 0.5283409555988332 118 Q8TD19,Q13277,P07602,P56589,Q9H0U9,P04062,P05067,Q96IX5,P16278,Q04656,P38571,Q9Y697,O43464,Q15904,P23229,P40855,P07686,O43709,P54098,O96000,Q15056,Q9UN37,O75844,Q9H9S5 24 +Aplasia hypoplasia involving the skeletal musculature 0.6496244898763982 1.3781901985504537 0.1681445726202928 1.0 0.5283409555988332 10 Q9Y487,O43505,Q9H9S5,Q9H173 4 +Abnormality of the external nose 0.3300347178082902 1.3777199983898831 0.1682897544575106 1.0 0.5283409555988332 239 Q10713,Q9BZK7,P56589,P04062,Q04656,Q96N67,Q15392,P16278,P98164,Q96ST3,P42892,Q9H9B1,O00192,P08069,Q96EK5,Q9UQR1,P10586,P21359,Q5KU26,Q9C0B1,O43395,Q93074,O43909,Q13620,P15586,Q8ND04,Q7LGA3,Q9UBM7,Q15555,O43292,P62258,Q9Y487,P40855,Q7LBC6,Q7Z3E5,O96028,Q15125,Q8WVQ1,Q93063,O00754,P10644,P31749,O60934,O75844,O95831 45 +Limitation of knee mobility 0.6450622244406659 1.3745362856237722 0.1692752533713417 1.0 0.5307162609079863 7 Q93063 1 +Telangiectasia of the skin 0.655010567983184 1.3729367082034922 0.1697720235596946 1.0 0.5313436210166427 19 Q8IZA0,P06280 2 +Anorexia 0.6540375106616414 1.37278525109834 0.1698191171763348 1.0 0.5313436210166427 28 Q9BZK7,P06280,P04062,O15460,Q14108,Q9Y697,P10644,P01889,P40763,Q9NZ08 10 +Abnormality of the pinna 0.3295992640146279 1.3694769895150338 0.1708502227758239 1.0 0.5338493820832181 239 O15111,Q69YQ0,Q8TD16,Q9BZK7,P04062,Q96N67,Q8N6M0,Q15392,P16278,Q9H9B1,Q96ST3,P42892,Q8IWS0,P60866,O00192,Q96EK5,Q9UQR1,P10586,P21359,P62857,Q93074,Q9H3S7,Q8ND04,Q8NCH0,Q7LGA3,Q15555,Q13555,Q9Y4U1,Q7LBC6,O43505,O96028,Q9ULC3,Q15125,P48449,Q96PZ0,Q15427,O43709,Q01105,P19022,O00754,P31749,Q15056,O60934,O75844,Q9H9S5 45 +Generalized joint laxity 0.6490446917484273 1.365233096475805 0.1721797991964759 1.0 0.5354039955303447 12 Q93074,Q8NCH0 2 +Buphthalmos 0.6379096798472876 1.3638986513478826 0.1725994653611113 1.0 0.5354039955303447 4 P31749 1 +Atrophy degeneration affecting the cerebrum 0.3266521384650242 1.3624706194704566 0.1730494102071762 1.0 0.5355746279730359 256 Q69YQ0,Q10713,P07602,Q8TD16,O60313,P17900,P05067,P04062,Q9NVC6,O75503,Q8N6M0,P16278,Q96N67,O14773,Q9H9B1,O75787,P49591,P17480,P04066,P15311,Q5KU26,Q9H490,Q92917,Q9NQX3,Q9H3S7,O43464,P50897,Q7LGA3,Q8NC96,P55263,P62258,Q9Y263,Q9Y4U1,P40855,P00403,Q9NWW5,Q9ULC3,O43709,Q96PZ0,Q8N3R9,Q9UHX1,P00374,P39880,Q9NQ11,Q9UBB6,Q01105,Q96RR1,P54098,O00754,P43034,Q96N66,Q9GZZ9,Q15056,Q9NUM4,Q9UN37,Q9H9S5,O95831 57 +Upper limb asymmetry 0.6374689238253884 1.3618098773885223 0.1732578935619184 1.0 0.5355746279730359 4 P31749 1 +Absent epiphyses 0.6437058649178335 1.361467918853745 0.1733658651256258 1.0 0.5355746279730359 8 Q7LGA3,Q8WVQ1 2 +Respiratory arrest 0.6416738105517675 1.3583059019327088 0.174366638311163 1.0 0.5368778896738798 7 Q9H0U9,Q14203,P13473 3 +Trichorrhexis nodosa 0.6357637905868013 1.3537279506143154 0.1758231874220812 1.0 0.5404242115725816 4 P51797 1 +Hypertelorism 0.3330132108967686 1.353587405379658 0.1758680472855349 1.0 0.5404242115725816 211 Q69YQ0,Q9BZK7,P56589,P04062,P16278,Q9H9B1,P98164,Q96ST3,Q14739,P60866,O00192,Q96EK5,Q969X5,P21359,P04066,P62857,Q93074,O43909,Q9H3S7,P51797,Q8NCH0,Q7LGA3,Q9UBM7,P55263,Q15555,O43292,Q9UPY3,P62258,Q9Y487,O96028,P63241,Q96PZ0,Q15125,Q8N3R9,Q9UBB6,Q01105,P19022,Q93063,O00754,P43034,P31749,P10644,Q10471,P40763,O75844,O95831 46 +High myopia 0.6450053048878143 1.3504426496886843 0.1768740380353193 1.0 0.5420785950890784 11 P98164,O15460 2 +Abnormality of the outer ear 0.3168092355480152 1.3499697987530268 0.1770256706252531 1.0 0.5421849634671722 353 O15111,Q69YQ0,Q8TD16,Q9BZK7,Q10713,P56589,P04062,Q96N67,Q8N6M0,Q15392,P16278,P98164,P42892,Q9H9B1,Q8IWS0,O75787,Q96ST3,Q14739,P60866,P08069,O00192,Q96EK5,Q9UQR1,Q9Y3D3,P10586,P21359,Q9H490,P62857,Q93074,Q92917,Q9H3S7,P15586,Q14671,Q8ND04,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q13555,P62258,Q9Y487,Q9Y4U1,P40855,Q7LBC6,Q7Z3E5,O43505,O96028,Q15427,Q15125,P48449,Q96PZ0,O43709,Q9ULC3,Q99519,Q8WVQ1,Q01105,P19022,Q93063,O00754,P31749,Q15056,Q10471,O60934,O75844,Q9H9S5,O95831,Q4J6C6 67 +Abnormality of digestive system morphology 0.3256387765815201 1.346394632143044 0.1781752811593497 1.0 0.5435518281157269 260 Q8TD19,Q13277,Q69YQ0,Q10713,Q04446,P56589,P04062,Q04656,Q15392,Q9H9B1,P98164,Q96ST3,P42892,Q14739,P60866,P08183,P38571,Q9NZ08,Q96EK5,Q9Y6B6,P62857,P06280,Q93074,O43909,Q9NQX3,P01889,Q8NCH0,Q9UBM7,P23229,Q8TAA9,Q9UPY3,P40855,P00403,Q7LBC6,Q7Z3E5,O96028,Q15427,O43709,Q9UDY2,P35670,P54098,Q96RR1,Q93063,P10644,P31749,Q15056,O60934,P40763,O75844,Q9H9S5,Q99643 51 +Supernumerary spleens 0.6396250895814825 1.3355768900940586 0.1816876078837919 1.0 0.547068466076067 9 Q15904,O96028 2 +Hepatitis 0.6477206549899334 1.3346282178288529 0.1819980578203162 1.0 0.5476476275878042 20 P35670,P08236,P11717 3 +Aortic valve calcification 0.6296462094878135 1.333640684715072 0.1823216426619471 1.0 0.5477715419205098 3 P04062 1 +Pseudobulbar signs 0.6415101435663897 1.333421167817332 0.1823936296582418 1.0 0.5477715419205098 11 P42356,P17900,P26358,Q14203 4 +Arthritis 0.626686564701978 1.32865807838914 0.1839608015229683 1.0 0.5502776701829215 44 P10321,Q8WVQ1,P06280,P28070,P35670,P04062,O15460,Q9UBS4,Q14108,Q13510,Q93063,P51798,O75844,Q14739,P01889,O00192,Q9NZ08 17 +Thick cerebral cortex 0.6322215443366805 1.3283612256701385 0.1840588023406753 1.0 0.5502776701829215 5 Q9Y487 1 +Metatarsus adductus 0.6400847382303814 1.3214160292158503 0.1863626842590733 1.0 0.5550131229653862 12 Q9UBM7,P08236,O96028,Q15392 4 +Corneal scarring 0.6246680436707033 1.319488392381187 0.187005888194041 1.0 0.5562195661037642 2 P09884 1 +Epiphyseal stippling 0.6420785445344835 1.3185600236373922 0.1873162458155535 1.0 0.556785533235078 15 Q9UBM7,Q99519,P56589,P08236,P10644,P40855,Q15125 7 +Severe short stature 0.6444753807111072 1.316333274419318 0.1880622073332283 1.0 0.5580461713017676 24 P16278,Q8WVQ1,P10619,Q15392 4 +Dementia 0.5688097358425868 1.3162164785849029 0.1881013943809926 1.0 0.5580461713017676 64 Q9NQ11,P07602,P35670,O15118,P17900,P05067,P06865,Q14108,Q13510,P61916,Q9NWW5,Q9Y287 12 +Abnormal tongue morphology 0.5133150635557503 1.315238301938022 0.1884298263327277 1.0 0.5585793351515683 77 O15111,O15460,P16278,Q9H9B1,P04066,Q9C0B1,P01889,P10253,Q7LGA3,Q9UBM7,Q9Y4U1,P07686,O43709,Q99519,O00754,P31749,Q15056,O75844,Q9H9S5,Q99643 20 +Bloody diarrhea 0.625526605310972 1.3141648486365816 0.1887907349113513 1.0 0.5586615429380576 3 Q6PGP7 1 +Abnormality of the nasal tip 0.3575160096746336 1.31322858035917 0.1891059361228613 1.0 0.5588809597206551 103 Q7LGA3,Q9BZK7,Q8ND04,Q9Y487,Q93074,O43909,Q93063,P10644,Q96N67,P16278,P98164,P42892,Q7LBC6,P08069,Q96EK5,O95831,P10586 17 +Abnormal 2nd finger morphology 0.63194123434013 1.3116484395768322 0.1896387810967383 1.0 0.5597422202072412 7 Q8WVQ1 1 +Chorioretinal dysplasia 0.6285742064548461 1.310997255575666 0.189858690817275 1.0 0.5600348278115167 5 O43505 1 +Abnormal cerebral ventricle morphology 0.3253958157952555 1.3089857182096734 0.1905391885481691 1.0 0.5613279652464168 245 Q69YQ0,Q10713,P07602,Q8TD16,Q9BZK7,P04062,Q8N6M0,Q15392,P16278,Q9H9B1,Q96ST3,O75787,O00584,O00192,Q96EK5,Q9Y3D3,Q9UQR1,P21359,P17480,Q5KU26,Q9H490,Q9C0B1,Q93074,P08236,O43909,O43464,Q9H3S7,P53634,Q8NCH0,Q9UBM7,Q8TAA9,P62258,Q9Y487,Q9Y4U1,P40855,P15291,Q7Z3E5,O43505,O96028,Q15427,Q15125,P39880,Q99519,Q01105,P10644,O00754,P31749,P51798,Q9H9S5 49 +Cystic liver disease 0.6293111127239723 1.3062625723868568 0.1914632803852798 1.0 0.5633345375295321 6 O43909,Q9UBS4 2 +Pace of progression 0.3390789078298655 1.3026477206575515 0.1926950578925721 1.0 0.564627104462002 175 Q10713,Q04446,O60313,P04062,Q04656,Q9UBS4,Q9NVC6,O14773,O75787,O00584,Q9BUF5,Q14108,P33993,P54802,P15586,Q14671,Q8N183,P55263,Q8IV08,Q5XKP0,Q13510,O60333,Q99720,Q14203,P41440,Q9BQP7,Q9UDY2,Q9NQ11,Q9BV79,Q96RR1,P54098,Q6IA86,P31749,Q9GZZ9,Q13126,Q6UWE0,O95831 37 +Thoracic kyphosis 0.6396181658555934 1.299920631498469 0.1936281731113269 1.0 0.5664692988752197 17 O43909,P08236,P04062,O00754,O95831 5 +Increased bone mineral density 0.640890082646482 1.299441598124195 0.1937924237299526 1.0 0.5665923510944454 26 Q14108,P04062,Q15392,P51798,Q15056,P54802,Q13126,O43709,Q15125 9 +Elfin facies 0.6302721561338479 1.2968123276685566 0.1946957680000058 1.0 0.567801431582407 8 Q9Y4P3,O43709,Q15056 3 +Avascular necrosis 0.6402671769694979 1.2951004986252102 0.1952855629368359 1.0 0.5688060020968018 25 Q04656,P04062,Q14108,O00754,Q8IWS0,P51798,O75844,P01889,Q9H173,Q9NX24,Q9NZ08 11 +Elevated circulating alanine aminotransferase concentration 0.6339637041881674 1.291457517749775 0.1965450770109269 1.0 0.5707103696954238 12 Q15904,P10253,P38571 3 +Generalized onset seizure 0.3420782330532051 1.2907917128609463 0.1967759121891015 1.0 0.5707103696954238 107 P00374,Q99519,Q9UBB6,P07602,Q01105,Q93074,O43909,Q14108,Q13510,P04062,P16278,O75503,Q96N66,Q9NQX3,Q96N67,P40763 16 +Neoplasm 0.3268891082114357 1.2893179386141982 0.197287577071868 1.0 0.5707103696954238 228 P07602,P04062,Q04656,Q15392,P42892,P11717,Q07954,P21359,P62857,O43909,Q13423,P53634,Q7LGA3,Q9UBM7,Q8TAA9,P10619,O96028,Q9UDY2,P35670,Q93063,P10644,P31749,O60934,P40763 24 +Ectrodactyly 0.6365719850894405 1.2877492098953045 0.1978332775040749 1.0 0.5707103696954238 16 Q9UBM7,Q93074,Q99720,P48449 4 +Progressive gait ataxia 0.6330136746060269 1.2868063526840678 0.198161792169349 1.0 0.5707103696954238 12 O14773,P07602 2 +Somatic mosaicism 0.6195855797282901 1.286065397661394 0.1984202389918645 1.0 0.5707659107973175 3 Q9UPY3 1 +Tissue ischemia 0.6374565290867006 1.2802971810364994 0.2004406387434079 1.0 0.576220236734769 22 P06280,Q9Y4P3,P05067,O15460,P31153,Q15056,O75844,P01889,Q9NZ08,O43709 10 +Insidious onset 0.6215150969677502 1.2773754911539594 0.2014697132508809 1.0 0.5766169267215586 5 O60313,P04062 2 +Woolly hair 0.6244232181216163 1.2755777774748491 0.202104813838079 1.0 0.5777805312991198 7 P14923,P15924,Q04656 3 +Diminished movement 0.6358798917857825 1.2731181410687722 0.2029761224730082 1.0 0.5795753507092101 21 Q9NQ11,P13473,Q96RR1,P54098,P04062,Q9NQX3,Q9Y3D3,O95831,Q14203 9 +Arteriosclerosis 0.6325750357692559 1.2646510345908817 0.2059964499189384 1.0 0.5845958117410682 17 Q99519,O15118,Q13510,P16278,P61916,P38571 6 +Retinal coloboma 0.6272322337141905 1.2638265339494394 0.2062922952336965 1.0 0.5845958117410682 11 Q9UHX1,Q10713,Q9Y467,O15078,Q9Y4U1,Q92620,Q9NP72,Q9H2M9 8 +Hydrocele testis 0.6203989748536463 1.263657584684066 0.2063529552709735 1.0 0.5845958117410682 6 P31749 1 +Abnormal thrombocyte morphology 0.3438511163743836 1.2632563647928603 0.2064970623347812 1.0 0.5845958117410682 131 P00374,Q9BZK7,P07602,P38571,P35670,P28070,P62857,Q14108,Q13510,P04062,P10644,O15460,Q9Y4U1,P51798,P01889,P40763,Q15904,P02786 18 +Blue irides 0.6244233365646553 1.2620807051065712 0.2069197474406201 1.0 0.5854099261025965 9 Q9Y4P3,P10644,O43709,Q15056 4 +Abnormal thalamic mri signal intensity 0.6194175188586177 1.2589643933507078 0.2080431931740489 1.0 0.588229443139064 6 Q96RR1,P31749 2 +Cns demyelination 0.6290962871482448 1.2582399440056138 0.2083049931581873 1.0 0.5886107576322452 14 Q9Y4U1,P40855,P07602,P51648 4 +Abnormal blood transition element cation concentration 0.6247800761017166 1.2576421958095847 0.2085211859094555 1.0 0.5888628130707342 10 P35670,Q15904 2 +Inappropriate behavior 0.6320616855323515 1.2569784262767614 0.2087614476822692 1.0 0.5891824911154488 19 P35670,P17900,P07602 3 +Motor delay 0.3244873133511012 1.2559790411164515 0.2091235690832842 1.0 0.5894869239144006 233 Q8TD16,P04062,Q8N6M0,Q9H9B1,O75787,P08069,Q5KU26,Q93074,O43909,P61457,P51797,Q14671,P10253,Q8NCH0,Q7LGA3,Q9Y487,Q13510,Q7LBC6,Q99720,Q96PZ0,P48449,Q99519,Q8WVQ1,Q9UBB6,Q9BV79,Q01105,P19022,Q93063,O00754,Q96N66,P51798,Q10471,P40763,P35270,Q9UN37,Q4J6C6 36 +Decreased circulating total igm 0.6228638160843462 1.2545367365701126 0.20964698165348 1.0 0.5899970976698713 9 Q15904 1 +Hydrocephalus 0.4860845744553583 1.252804022415934 0.2102770374251972 1.0 0.5901841960341757 81 Q10713,P04062,Q15392,P21359,Q9H490,Q9C0B1,Q93074,P08236,Q9UBM7,Q8TAA9,Q9Y4U1,P40855,P15291,Q7Z3E5,O96028,O43505,Q15427,Q15125,Q99519,P10644,O00754,P31749,P51798,Q9H9S5 24 +Abnormality of the inner ear 0.6221426472310074 1.2510480391217416 0.2109169512941764 1.0 0.5901841960341757 9 P31749 1 +Lymphedema 0.6275692324736988 1.2465767063790114 0.2125527471685315 1.0 0.5930247223949945 15 P31749,P06280 2 +Abnormal auditory evoked potentials 0.6208370931817027 1.2447321575759742 0.2132302211978947 1.0 0.5945571471404917 9 Q15125,P07602 2 +Diarrhea 0.5182792319038514 1.2427750764760097 0.2139507292652105 1.0 0.5951324328488183 74 Q13277,Q04656,P42892,P38571,P02786,Q9Y6B6,P06280,O43464,Q13423,P54802,P01889,P15586,Q15904,P23229,Q13510,P07686,P00403,O60333,Q9BQP7,O60934 20 +Abnormal oral mucosa morphology 0.5547002147437694 1.242048644206784 0.2142186149375495 1.0 0.5951657983615443 65 Q9UBM7,P23229,Q99519,Q9BZK7,O43909,P08236,P04062,Q14108,Q9Y4U1,P16278,Q15392,P10644,O00754,Q15056,P01889,P40763,P53634,Q9NZ08 18 +Abnormality of the optic nerve 0.3198489020057777 1.2412151663814586 0.2145262735805664 1.0 0.5953071996367962 268 Q13277,Q10713,P07602,P56589,Q7KZN9,O60313,P04062,O15460,P16278,Q9Y287,Q9H173,O00192,Q9NZ08,Q5KU26,Q9H490,P06280,O43395,Q93074,Q9H3S7,P61586,P01889,P50897,Q8ND04,Q8N183,Q7LGA3,Q8NC96,Q9UBM7,Q13144,P04114,Q15555,Q9Y467,O43292,Q9Y263,Q5XKP0,Q9Y4U1,O94886,P40855,P00403,O43505,O96028,Q9ULC3,Q15125,Q96PZ0,P04439,Q8N3R9,Q9UHX1,P41440,Q99519,Q9BV79,O75489,Q96RR1,P54098,P10644,O00754,O96000,P31749,P51798,Q9GZZ9,P29992,Q9H9S5,O95831 61 +Joint hypermobility 0.372346260459495 1.238562904740522 0.2155074128330385 1.0 0.595946280499966 100 Q04656,Q8N6M0,Q8IWS0,Q96ST3,O00192,P21359,Q9H490,Q93074,Q9H3S7,Q13620,Q15904,Q7LGA3,Q9Y263,Q9Y487,O43567,Q7LBC6,O43709,P63241,Q96PZ0,Q8N3R9,Q8WVQ1,Q01105,P35670,Q15056,P40763 25 +Retinal hamartoma 0.6202139700707128 1.235463467451611 0.2166580647011304 1.0 0.5983582168071125 10 P21359,O60333,P31749 3 +Dermal atrophy 0.6277413673662628 1.233305757733796 0.2174617105497658 1.0 0.6002202094162287 28 P10644,Q15392,P53634,Q8NCH0,Q07954 5 +Testicular atrophy 0.6118502700760291 1.2313233054537085 0.218201968763295 1.0 0.6015472824942919 5 P54098 1 +Abnormal large intestine physiology 0.6272466147730329 1.2305967276939969 0.2184737297319157 1.0 0.6016251958330696 20 P07602,P06280 2 +Depressed nasal bridge 0.337659365104481 1.2305539975568225 0.2184897195995017 1.0 0.6016251958330696 166 Q69YQ0,P56589,P04062,Q15392,P16278,P98164,Q96ST3,Q14739,P60866,P21359,Q9H490,P62857,Q93074,O43909,Q9H3S7,Q13620,P15586,Q7LGA3,Q9UBM7,Q15555,Q9UPY3,P40855,Q9ULC3,Q96PZ0,Q8WVQ1,P19022,P10644,O00754,P31749,O60934,O95831,Q4J6C6 32 +Blindness 0.4625512630450543 1.2299415305261128 0.2187190007514976 1.0 0.6018991136407683 85 P21359,Q15555,Q13144,P07602,O43395,P54098,P06865,P17900,Q9NZ08,O96000,P07686,P31749,P16278,P51798,P01889,P50897,O43505,Q8N183 18 +Spinal muscular atrophy 0.6206647530773522 1.226327753088862 0.2200753614846331 1.0 0.6052332338192521 12 Q99720,Q13510,Q8TD16 3 +Megalocornea 0.6225750860790438 1.22601879173568 0.2201916035050848 1.0 0.6052332338192521 14 Q9Y4P3,Q9H9S5,Q15056,O96028,Q96EK5,O43709 6 +Cardiomegaly 0.6193045706377897 1.2245007779474932 0.2207633730212164 1.0 0.6064453558645619 37 Q99519,P04066,P13473,P04062,P10644,P10253,P07686,P54802,Q07021 9 +Abnormality of the forehead 0.3209196774703128 1.221768676073004 0.2217951172043659 1.0 0.6085585553116243 315 Q69YQ0,Q9BZK7,Q10713,P56589,Q04656,Q96N67,Q15392,P16278,P98164,Q96ST3,O75787,Q14739,P60866,Q96EK5,Q9UQR1,Q07954,P21359,P04066,Q9H490,P62857,Q93074,O43909,Q92917,Q9H3S7,Q13620,P15586,Q14671,Q8ND04,Q15904,Q8NCH0,Q7LGA3,Q9UBM7,O43292,Q8NC96,Q13555,Q9UPY3,P62258,P55263,Q9Y487,Q9Y4U1,P40855,Q9NX62,O43567,O96028,O43709,Q15125,Q96PZ0,P63241,Q8N3R9,Q9UHX1,Q99519,Q8NCM8,P19022,Q93063,O00754,P43034,P51798,Q15056,Q9GZZ9,Q10471,P40763,O60934,Q9H9S5,O95831,Q4J6C6 65 +Ocular anterior segment dysgenesis 0.3905898846424358 1.2207387179839435 0.2221849631940904 1.0 0.6085903982383187 97 Q9H9B1,Q9H1A4,P98164,P60866,Q9H173,Q6W2J9,P08069,P21359,P46783,P62857,Q9Y4P3,Q9BXW9,Q8NFV4,Q9H2M9,Q7LGA3,Q9Y297,P61313,P00403,O60333,O96028,O43709,P48449,Q99519,Q8WVQ1,O15078,P19022,P31749,O94979,Q15056,Q9UN37,Q9H9S5,Q99643 32 +Viral encephalitis 0.6037179108881741 1.2206977964007282 0.2222004624148099 1.0 0.6085903982383187 2 P42224 1 +Paresthesia 0.6250685177786088 1.2191122363626583 0.2228015962121108 1.0 0.6098766243421239 28 Q04446,P06280,P54098,P05067,O15460,Q7LG56,P54802,P01889,P60866,P29992,Q9NZ08 11 +Retinal detachment 0.6236466583387469 1.2144101597204666 0.2245911376970617 1.0 0.614050180130469 19 P98164,O43505,Q8NCH0,P31749 4 +Congenital ichthyosiform erythroderma 0.609914696576462 1.2135181250793352 0.2249317889245963 1.0 0.6143289865057964 6 P04062 1 +Abnormal macular morphology 0.6242979071431907 1.213449317788375 0.2249580804586677 1.0 0.6143289865057964 27 Q99519,Q9Y4U1,P04062,Q13510,P50897,P04439 6 +Congenital onset 0.3380483779846622 1.212235504147042 0.2254222443812297 1.0 0.6152109077869463 113 Q8TD19,Q8TEQ6,O15111,Q8TD16,P07602,P08069,Q96EK5,Q9Y3D3,Q969X5,Q5KU26,P61586,Q8NB49,Q13472,Q7LGA3,P23229,Q9Y263,Q5XKP0,O43567,Q7Z3E5,O43505,P63241,Q15125,Q9UHX1,Q96N66,Q6IA86,P11233,Q9H9S5,Q4J6C6 28 +Toe walking 0.6241193341592638 1.210823462309112 0.2259630710784814 1.0 0.6152109077869463 25 Q8TD16,P07602,Q8ND04,Q6UWE0,Q99720 5 +Cerebellar dysplasia 0.6093292435713198 1.2107182476742449 0.2260034064190259 1.0 0.6152109077869463 6 P42356,Q9H9S5,Q7Z3E5 3 +Dysgraphia 0.6215437744117494 1.2093874155210342 0.2265140411174373 1.0 0.6152109077869463 17 Q9Y4P3,P05067,Q15056,Q9NUM4,P60866,O43709 6 +Abnormality of visual evoked potentials 0.6229578421041178 1.2087915846761506 0.2267429254445219 1.0 0.6152176391376525 20 P07602 1 +Abnormal hdl cholesterol concentration 0.6038290134546906 1.2021523415843205 0.2293045102139113 1.0 0.621077695012796 4 P38571 1 +Neoplasm of the gastrointestinal tract 0.4015185419734076 1.2012607220998723 0.2296500814561504 1.0 0.6212878808122342 95 P21359,Q9UDY2,P07602,P35670,P10644,Q04656,P31749,P42892,P11717 9 +Molar tooth sign on mri 0.6071645266599224 1.2003660062466792 0.229997225039666 1.0 0.621864217206374 6 Q10713,Q7Z3E5 2 +Abnormality of the calvaria 0.3175505441496561 1.199286019035404 0.2304167495354654 1.0 0.6226354706270124 271 O15111,Q69YQ0,Q10713,Q9BZK7,P56589,P04062,Q04656,Q8N6M0,Q15392,P16278,P98164,Q9H9B1,Q8IWS0,Q14739,Q9UQR1,Q969X5,P04066,Q9C0B1,Q93074,O43909,P54802,P15586,Q8ND04,Q8NCH0,Q9UBM7,Q9UPY3,P62258,Q9Y487,Q32P28,P40855,Q9NX62,Q7Z3E5,O96028,Q9ULC3,Q15125,Q99519,Q01105,P19022,Q93063,O00754,P10644,P31749,P51798,Q10471,P40763,O75844,O95831,Q4J6C6 48 +Abnormal retinal vascular morphology 0.5773823260147043 1.198427423171699 0.2307506618009263 1.0 0.6228118851984256 56 P21359,Q99519,P10619,P07602,P06865,P17900,Q13510,P16278,P07686,Q15056,P04439 11 +Vertical supranuclear gaze palsy 0.6155519843509261 1.1961027240472089 0.2316564747416558 1.0 0.6247405212215887 13 Q9NQ11,Q96RR1,O15118,P61916,Q14203 5 +Bifid scrotum 0.6078246741120679 1.1959023273603355 0.2317346768387174 1.0 0.6247405212215887 7 Q9UBM7,Q96EK5 2 +Abnormal shape of the frontal region 0.3368183237771964 1.1951555997011238 0.2320262422701762 1.0 0.6251630943676973 113 Q99519,P04066,P62258,Q9Y487,Q93074,O43909,P19022,O00754,Q15392,P16278,P51798,P40763,P15586,Q8ND04,O96028,Q15125,Q4J6C6 17 +Partial agenesis of the corpus callosum 0.6162581102235715 1.1948053340683251 0.2321630958109992 1.0 0.6251685686850195 14 P98164,Q15392 2 +Abnormal heart valve physiology 0.4477655454137889 1.193644987406449 0.2326168682741383 1.0 0.6260269403291813 87 Q8TD19,P04062,P16278,Q9H9B1,Q6W2J9,Q9NZ08,Q9UQR1,P21359,P06280,Q9Y4J8,Q9Y4P3,P01889,Q8NFV4,Q15904,P55263,P04114,P60953,Q9ULC3,O43709,Q15125,Q9UHX1,P54098,P09493,P10644,O00754,P31153,P19022,Q15056,O75844 29 +Gastrointestinal obstruction 0.6182400557366882 1.192835985335374 0.2329336138040838 1.0 0.6261525607011807 17 P42892,Q93063 2 +Mixed demyelinating and axonal polyneuropathy 0.6034179716326981 1.1911418539376433 0.2335979015076681 1.0 0.6275744318024665 5 P35670 1 +Bell shaped thorax 0.6006289054069502 1.1869578610923552 0.2352442423997269 1.0 0.6301718960182172 4 Q8WVQ1 1 +Abnormal hair quantity 0.3219975968983135 1.1865172880290873 0.2354180783276238 1.0 0.6302423081126083 222 Q7KZN9,Q04656,O15460,Q96N67,P16278,Q9H9B1,Q8IWS0,P08069,Q96EK5,Q07954,P21359,Q14574,Q9H490,Q93074,P08236,P54802,P01889,P15586,P53634,Q8N183,Q15555,Q9Y487,P00403,Q15427,Q15125,P48449,Q99519,Q8WVQ1,P19022,Q93063,O00754,P10644,P31749,O60934,P29992 35 +Abnormality of the phalanges of the hallux 0.6041663230548941 1.186029088162061 0.2356108124237339 1.0 0.6302423081126083 6 Q8WVQ1 1 +Hyperkeratosis 0.5503760919370342 1.1858582700928766 0.2356782752355537 1.0 0.6302423081126083 64 Q14574,P04066,Q99519,P06280,P04062,P31749,Q14126,P53634,Q07954 9 +Abnormal coronary artery morphology 0.604990334347163 1.1822984946471748 0.237087282681776 1.0 0.6329152157716726 7 P16278 1 +Motor seizure 0.3355753516955502 1.1814885313928514 0.2374087067711092 1.0 0.6330443779744874 112 P07602,Q9UBX3,P04062,Q96N67,P16278,O75503,Q9H9B1,O75787,O43909,O43292,Q5XKP0,Q9Y4U1,Q13510,P07686,O43567,Q99519,Q9UBB6,Q01105,P19022,Q96N66,P40763 21 +Renal duplication 0.6086920771343494 1.1794988065273695 0.2381996116534548 1.0 0.6347882754236035 10 P23229,Q9Y4P3,Q9BXW9,Q15056,O43709 5 +Epidermal acanthosis 0.6108210219236967 1.1781135079701135 0.238751357579007 1.0 0.6352378607187684 12 Q14574 1 +Bilateral tonic clonic seizure with generalized onset 0.6056222633844561 1.1780434239166 0.2387792950685385 1.0 0.6352378607187684 8 Q13510 1 +Abnormality of skull ossification 0.61172414807525 1.1772743927314595 0.2390860042252414 1.0 0.6356891064176861 13 O75844,P54802,Q93063,Q32P28 4 +Functional motor deficit 0.3369704478381629 1.1736047075096625 0.2405533947663751 1.0 0.6377622021336087 148 Q8TD16,P07602,P04062,O14773,O75787,P07384,Q9NQX3,Q13472,Q07021,O43292,P13473,Q13510,P00403,Q99720,Q9BQP7,Q9NQ11,P35670,Q96RR1,P54098,Q93063,P10644,Q15041,P31749,Q9GZZ9,P46020 25 +Persistence of primary teeth 0.6060290828602395 1.1730969660185049 0.2407569230539936 1.0 0.6379370584007821 9 Q9H9B1,P61586,O75844,P40763,Q9ULC3 5 +Keratoconjunctivitis 0.605549835721185 1.1707791888406955 0.2416875450678137 1.0 0.6393069860122376 9 Q9NZ08,P01889 2 +Skeletal muscle hypertrophy 0.5980822054615714 1.169972741504013 0.2420119385740542 1.0 0.6397054775280681 45 Q7LGA3,P04066,Q10713,Q9C0B1,O00754,Q9H9S5,P16278,Q9H9B1,P07686,P31749,Q15056,O43709,P10253,Q99643 14 +Fat malabsorption 0.6046691747691857 1.166520258121657 0.2434041628677214 1.0 0.6405874232281727 9 P38571,Q9Y6B6 2 +Nephrolithiasis 0.6151076784780846 1.1637798465412894 0.2445132414426938 1.0 0.6421310239273165 25 Q9BQP7,P35670,Q9Y4P3,Q9UBS4,Q15056,P29992,O43709,Q8NCH0,Q4J6C6 9 +Hiatus hernia 0.6047912471588496 1.1605573284615205 0.2458219671908348 1.0 0.6433105136721591 10 Q04656,Q9NQX3,Q8NCH0 3 +Reduced systolic function 0.5929929599795902 1.1602348500216355 0.2459532016368402 1.0 0.6433105136721591 3 P15924 1 +Female sexual dysfunction 0.5963744717778343 1.1575894751959732 0.2470316063302515 1.0 0.6438929502829548 5 P01889 1 +High frequency sensorineural hearing impairment 0.5961209939679719 1.1563823440234835 0.2475248002100529 1.0 0.6445475007947397 5 Q13510 1 +Abnormal epidermal morphology 0.6130162604461968 1.1562944720610064 0.2475607286856656 1.0 0.6445475007947397 21 Q14574,P31749,Q07954 3 +Fatigue 0.4542967600392517 1.1535872750087408 0.2486694178009654 1.0 0.6456215511439399 85 Q9BZK7,P07602,Q99643,O60313,P04062,Q04656,O15460,Q14739,Q9NZ08,P21359,P06280,Q13423,P01889,Q70HW3,Q07021,O60333,Q14203,Q9NQ11,Q96RR1,P54098,P10644,P40763,Q4J6C6 23 +Male sexual dysfunction 0.6017216934349856 1.1522681887137414 0.2492108847718144 1.0 0.6459423547718857 9 P07686 1 +Food intolerance 0.5907354871119901 1.1495590571617194 0.2503255295682218 1.0 0.6483968911528998 3 Q96MW5 1 +Abscess 0.6011051179381206 1.149287304753854 0.2504375311742168 1.0 0.6483968911528998 9 P53634 1 +Generalized hyperpigmentation 0.6048753648365683 1.1435976209991965 0.2527905487481294 1.0 0.6526669123302207 13 Q13423,P31749 2 +Akinesia 0.6011261850672809 1.1427660683570604 0.2531357304317718 1.0 0.6531944251597808 10 Q9NQ11 1 +Abnormality of globe location 0.3135085432404457 1.1393938153723489 0.2545389343515218 1.0 0.6546295277803699 284 Q69YQ0,Q9BZK7,P56589,P04062,P16278,Q9H9B1,P98164,Q96ST3,Q8IWS0,Q14739,P60866,P08069,Q96EK5,Q969X5,P21359,P04066,Q5KU26,P62857,Q9H490,Q93074,O43909,Q92917,P51797,Q15904,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,O43292,Q9UPY3,P62258,Q9Y487,Q32P28,Q9NX62,O96028,Q15125,Q96PZ0,Q8WVQ1,Q9UBB6,Q01105,P19022,Q93063,O00754,P10644,P31749,Q10471,P40763,O75844,O95831 49 +Metaphyseal widening 0.6092523841881239 1.1370700979787036 0.2555089830039778 1.0 0.656396207307172 21 Q8WVQ1,Q96HY6,P34059,Q04656,Q93063,P16278,Q14739,O95831 8 +Pollakisuria 0.5899917001741501 1.136474979529758 0.2557578312380255 1.0 0.6566716851886625 4 Q06787,O60934 2 +Tongue nodules 0.5857185010327572 1.135833904883114 0.2560260843808919 1.0 0.6567355595464158 2 Q2M1P5 1 +Nephrotic syndrome 0.6096999232083206 1.1357386313843243 0.2560659675781582 1.0 0.6567355595464158 26 Q14108,Q8NCH0,P06280 3 +Schizophrenia 0.607144224046552 1.1339006292230245 0.2568362331624321 1.0 0.6576198857946978 18 P04062,P07602 2 +Hamartoma of the eye 0.600472341434446 1.1333339718844329 0.2570740306310139 1.0 0.6578654967086158 11 P21359,O60333,P31749 3 +Hypocholesterolemia 0.5971994459364631 1.1304094895087224 0.2583037173533047 1.0 0.6589468921261242 9 Q9Y6B6,P07602 2 +Abnormality of fibula morphology 0.6029014771754031 1.128837353613695 0.2589664519179151 1.0 0.6599014313006806 14 Q8WVQ1,Q96HY6,Q04656,Q93063,Q15427 5 +Arthralgia 0.6030747036294659 1.1276912167886834 0.2594503483000832 1.0 0.6603101054250989 36 P04114,P28070,P06280,P35670,O15460,Q13510,Q15056,P01889 8 +Abnormality of bladder morphology 0.6016375855443045 1.1276841994405415 0.2594533129360643 1.0 0.6603101054250989 13 P23229,Q9Y4P3,Q04656,Q15056,O43709 5 +Megaloblastic anemia 0.596278780852169 1.1259607727910146 0.2601821236518444 1.0 0.6618017045384547 9 P00374,Q9Y4U1 2 +Talipes calcaneovalgus 0.5912842677166463 1.124464588279899 0.2608159850852125 1.0 0.662636106338458 6 Q9UBM7,Q69YQ0 2 +Lower limb asymmetry 0.5973402022017151 1.12439504264968 0.2608454741800803 1.0 0.662636106338458 10 Q93063 1 +Sound sensitivity 0.5971070509800889 1.123263984492758 0.2613253950179415 1.0 0.662636106338458 10 Q9Y4P3,P17900,O43709,Q15056 4 +Hyperacusis 0.5971070509800889 1.123263984492758 0.2613253950179415 1.0 0.662636106338458 10 Q9Y4P3,P17900,O43709,Q15056 4 +Retinal pigment epithelial atrophy 0.5871867225105059 1.1231722500053496 0.2613643457503543 1.0 0.662636106338458 4 P51648,P50213 2 +Epistaxis 0.6026984990017616 1.1231646485340516 0.261367573537425 1.0 0.662636106338458 15 Q9BZK7,P04062,P10644,P01889,P40763 5 +Abnormality of muscle size 0.3224239962224909 1.1205048823362838 0.2624986732160634 1.0 0.6644139452526672 203 Q10713,Q04446,Q8TD16,Q04656,P16278,Q9H9B1,Q8IWS0,Q9H173,P07384,Q969X5,P04066,Q9C0B1,P10253,Q7LGA3,P13473,Q9Y487,Q13510,P07686,O60333,Q6P4A7,O43505,O43709,Q99720,Q14203,Q9BQP7,Q99519,P54098,P10644,O00754,P31749,Q15056,O60934,P46020,Q13126,Q6UWE0,Q9H9S5,O95831,Q99643 38 +Radial deviation of the hand or of fingers of the hand 0.6008228208927214 1.1185783309286168 0.2633200720896989 1.0 0.6655499305904687 14 Q8WVQ1,Q93074,Q96ST3,Q6W2J9,P08069,Q15427 6 +Abnormality of the glabella 0.5916458209624901 1.118289812883378 0.2634432363475429 1.0 0.6655499305904687 7 P21359 1 +Opisthotonus 0.6063388849566439 1.1181062840526863 0.2635216028820575 1.0 0.6655499305904687 26 P07602,O43909,P04062,P11117,Q99720 5 +Facial telangiectasia 0.5830165404230936 1.1130767926504848 0.2656754498506704 1.0 0.6691918705878004 3 P46100 1 +Abnormality of the metacarpal bones 0.589945924554084 1.1115248667710609 0.2663424925392739 1.0 0.6703990914105997 44 Q9UBM7,Q8WVQ1,P34059,O43909,P08236,P10644,Q93063,P16278,Q9NX62,P31749,O43567,Q9H173,O96028 13 +Occipital encephalocele 0.5901168110336706 1.1109621211471392 0.2665846541466949 1.0 0.6703990914105997 7 O43505,Q9H9S5 2 +Abnormal testis morphology 0.3166921210661977 1.110433735874732 0.2668121676077426 1.0 0.6703990914105997 234 Q69YQ0,Q9BZK7,Q9UBX3,P56589,Q9H0U9,Q8N6M0,Q9H9B1,Q9H1A4,Q8IWS0,Q96ST3,Q6W2J9,O00192,Q9NZ08,P21359,Q5KU26,Q9C0B1,O43395,Q9Y4P3,Q93074,Q9BXW9,Q9H3S7,Q13620,P50213,Q13423,P01889,Q8NFV4,Q9H2M9,Q9NX24,Q8WYQ5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,P60953,Q9UPY3,Q9Y487,P40855,P41227,O75381,Q7LBC6,O43505,O96028,O43709,P63241,P48449,Q96PZ0,Q8N3R9,Q15125,Q9ULC3,Q9BUR4,Q8NCM8,O15078,P19022,Q93063,O15344,P10644,P31749,O43172,P54098,Q15056,Q9H9S5 62 +Confusion 0.6034957469173609 1.109885935489436 0.2670481818566812 1.0 0.6703990914105997 20 Q9NQ11,O00754,P05067,P01889,Q9NZ08 5 +Hip contracture 0.5966977949023196 1.108991947317704 0.267433655884127 1.0 0.6703990914105997 12 Q7LGA3,Q8TD16 2 +Premature loss of teeth 0.5966775116499329 1.108892760316171 0.2674764473654463 1.0 0.6703990914105997 12 Q5JRA6,P53634,P51798 3 +Abnormality of the posterior pituitary 0.5879770511236302 1.1086738128591322 0.2675709228367928 1.0 0.6703990914105997 6 Q9UHX1,P31749 2 +Episodic pain 0.5997567295256158 1.1085826931142395 0.2676102476172137 1.0 0.6703990914105997 15 P21359,O60333,Q13423,P07686 4 +Abnormality of facial skeleton 0.3151551256492656 1.107103223502767 0.2682493020210974 1.0 0.6716371563022833 336 Q8TD19,O15111,Q69YQ0,Q8TD16,Q9BZK7,P34059,P56589,P04062,Q04656,Q8N6M0,Q15392,P16278,P98164,Q9H9B1,Q96ST3,O75787,Q14739,P60866,P08069,O00192,Q96EK5,Q969X5,P21359,P04066,Q9H490,P62857,P28070,Q9C0B1,Q93074,O43909,Q92917,Q9H3S7,Q13620,P61586,Q9NX24,Q8ND04,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q9Y487,Q9Y263,P40855,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,O43709,P63241,Q8N3R9,Q9UHX1,Q9HC07,Q8WVQ1,Q9BUR4,Q8NCM8,Q93063,O00754,P10644,P31749,P51798,Q15056,O60934,O75844,Q9H9S5,O95831,Q4J6C6 70 +Hyperhidrosis 0.598963907175713 1.1047504859569468 0.2692677207494662 1.0 0.6738232170077038 36 P21359,P07858,P04066,Q9Y263,O15460,Q13620,P07686,O60333,P51797,P01889,P35270,Q9NX24,Q99643 13 +Abnormal urine cytology 0.5916444325673387 1.1034627642739558 0.269826253212021 1.0 0.6744929035817474 42 P21359,P23229,Q9BZK7,P06280,Q9Y4U1,P04062,O15460,Q9UBS4,Q14108,P10644,O60333,P01889,P40763,Q99643 14 +Fragile skin 0.5911726912547548 1.1012982590379925 0.2707668686469415 1.0 0.6757513293411561 9 Q8NCH0 1 +Melanocytic nevus 0.5931157394485701 1.0975060657596245 0.2724202306098309 1.0 0.6792832316148778 11 P10644,P31749 2 +Peptic ulcer 0.5943026217720732 1.097281515922616 0.2725183485038038 1.0 0.6792832316148778 12 Q9Y4P3,P04062,Q15056,P29992,O43709 5 +Abnormality of facial soft tissue 0.3317904256964358 1.097045408019948 0.2726215428154599 1.0 0.6792832316148778 123 P56589,O60313,P04062,Q9H1A4,O75787,Q9P2R3,Q9BUF5,P42356,Q9Y5K6,P28070,Q9Y4P3,Q93074,P10253,Q9UBM7,Q13555,Q9Y263,Q7LG56,Q13510,P40855,O43709,Q14203,Q9UHX1,Q9BQP7,Q99519,Q9NQ11,Q96RR1,P54098,P52565,O00754,P31749,P51798,Q15056,P35270,O75844,Q9H9S5,Q99643 36 +Abnormal lip morphology 0.3130282762951173 1.096117508856476 0.2730273533041307 1.0 0.6795094249499786 302 Q8TD19,O15111,Q69YQ0,Q9BZK7,P04062,Q04656,Q8N6M0,P16278,Q96N67,Q9H9B1,Q96ST3,Q14739,O00192,P08069,Q96EK5,Q9UQR1,P10586,P21359,Q14574,P04066,Q5KU26,Q96HY6,P06280,Q9H490,Q93074,O43909,Q9H3S7,Q13620,P51797,P15586,Q8ND04,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q13555,P62258,Q9Y263,Q9Y487,Q9Y4U1,Q7LBC6,O96028,Q15427,O43709,P63241,Q96PZ0,Q8N3R9,Q9UHX1,Q99519,Q8WVQ1,Q8NCM8,Q01105,P19022,Q93063,P43034,Q15056,Q10471,O60934,O75844,Q9H9S5,Q4J6C6 61 +Abnormal cerebral cortex morphology 0.3158596278252873 1.0945420981299685 0.2737172944339159 1.0 0.6795094249499786 234 Q69YQ0,Q10713,Q8TD16,P56589,Q9BZK7,P04062,P05067,Q8N6M0,Q15392,O75503,Q96N67,Q96ST3,Q9H9B1,Q96EK5,P49591,P17480,P15311,Q5KU26,Q9C0B1,Q92917,Q9NQX3,Q9H3S7,Q7LGA3,Q9UBM7,P62258,Q9Y487,Q9Y4U1,P40855,P00403,P23258,Q7Z3E5,O43505,Q15427,O43709,Q96PZ0,P39880,Q9NQ11,Q9UBB6,Q01105,Q96RR1,O00754,Q96N66,Q15056,Q9NUM4,Q9UN37,Q9H9S5 46 +Spinal cord compression 0.5866617898376008 1.0944107646019434 0.2737748648842564 1.0 0.6795094249499786 7 O43909,Q93063,P31749 3 +Femoral hernia 0.5790616892065188 1.09440123732347 0.2737790415176011 1.0 0.6795094249499786 3 Q04656 1 +Aqueductal stenosis 0.5827582456989775 1.0927982661991218 0.2744823830525154 1.0 0.6795094249499786 5 P21359 1 +Abnormal pharynx morphology 0.5878730223286545 1.0900680622041734 0.2756831636708949 1.0 0.6795094249499786 43 Q13277,P34059,Q93074,P08236,Q13510,P16278,P54802,P01889,P40763,P15586 10 +Multiple lipomas 0.5868621129060968 1.0877501714004876 0.276705412354403 1.0 0.6795094249499786 8 Q8TAA9,P31749 2 +Frontotemporal dementia 0.5910986604281132 1.0876897954533875 0.2767320741606862 1.0 0.6795094249499786 11 Q9NUM4,P05067 2 +Oculogyric crisis 0.5932256954600061 1.0863729037104737 0.2773140445573485 1.0 0.6795094249499786 13 P61457,P35270,Q9NQ11,Q01105 4 +Abnormal arachnoid mater morphology 0.5880406190288469 1.0861804516196265 0.2773991641620399 1.0 0.6795094249499786 9 Q15904,Q9UBS4 2 +Abnormal exteroceptive sensation 0.5543311426291186 1.0832737492471736 0.2786869334683179 1.0 0.6815776954074844 58 Q9NQ11,P07602,Q04446,P06280,P54098,P05067,O15460,P07686,P54802,P01889,P60866,O95831,P29992,Q9NZ08,Q8NCH0 15 +Facial hypotonia 0.5898530710097076 1.081629859203775 0.2794170311985815 1.0 0.6830030435781879 11 P10253 1 +Elevated alkaline phosphatase of bone origin 0.5736205370315811 1.0788917099074058 0.280636004893573 1.0 0.6848995551007884 2 P55072 1 +Elevated tissue non specific alkaline phosphatase 0.5736205370315811 1.0788917099074058 0.280636004893573 1.0 0.6848995551007884 2 P55072 1 +Leukoencephalopathy 0.3525646959829108 1.0770333145360718 0.2814653826864848 1.0 0.686562324838101 101 P07602,O60313,P17900,O75503,O00584,Q5JPH6,Q8N183,Q13144,Q9Y263,Q9Y4U1,Q7LG56,Q9NWW5,O96028,P39880,Q9UHX1,Q9NQ11,Q01105,P54098,O96000,Q9H9S5,O95831 21 +Abnormal renal physiology 0.3261684741609169 1.07497325254413 0.2823867036744469 1.0 0.6884474999676187 173 Q8TD19,Q13277,Q10713,Q9BZK7,P04062,Q9UNF1,Q9UBS4,O15460,Q9H9B1,P98164,Q9P2R3,Q6W2J9,Q9NZ08,P21359,Q9Y5K6,P06280,Q9Y6M9,Q9Y4P3,Q14108,Q9BXW9,Q9Y697,P01889,Q07021,Q8NCH0,Q8N183,P23229,Q8TAA9,P62258,Q9Y4U1,Q7LG56,P40855,P00403,O60333,O43709,O43772,Q8NCM8,P35670,O75489,P52565,P10644,P43034,O96000,Q15056,P40763,P50416,Q99643 46 +Abnormal epiglottis morphology 0.578912587530694 1.0745253008323306 0.2825873113394586 1.0 0.6885745468634101 5 Q15427,Q13510 2 +Pruritus 0.5978977603489823 1.0740242130940352 0.2828118295307908 1.0 0.6887596919822885 25 Q13277,Q9UDY2,P35670,P40763,P38571,Q07954 6 +Cerebral hemorrhage 0.5914713408349604 1.0724650013371828 0.2835112257072691 1.0 0.6892293383041886 14 P05067,P31749 2 +Joint dislocation 0.401562500812705 1.0716621656212464 0.2838718002073415 1.0 0.6892293383041886 93 Q8TD16,P51571,Q04656,Q9H173,O00192,Q969X5,Q9Y4P3,O43909,Q9BXW9,Q9NQX3,Q8NCH0,Q9UBM7,P62258,Q9Y487,Q9NX62,O96028,Q15427,O43709,Q15125,Q9UHX1,Q8WVQ1,P10644,P43034,P31749,P51798,Q15056,O75844,Q9H9S5 28 +Parkinsonism with favorable response to dopaminergic medication 0.5887501694833143 1.0701537193092314 0.2845501222866113 1.0 0.6892293383041886 12 Q9NQ11,P07602 2 +Pheochromocytoma 0.586023591214113 1.06954474792093 0.284824276629612 1.0 0.6892293383041886 10 P21359,O60333,P10644 3 +Elevated calcitonin 0.586023591214113 1.06954474792093 0.284824276629612 1.0 0.6892293383041886 10 P21359,O60333,P10644 3 +Hypertension associated with pheochromocytoma 0.586023591214113 1.06954474792093 0.284824276629612 1.0 0.6892293383041886 10 P21359,O60333,P10644 3 +Scarring 0.5940192803934592 1.0683683837147846 0.2853543727585179 1.0 0.6892293383041886 34 P23229,P04439,O43395,Q04656,Q92542,P53634,Q8NCH0,Q07954 8 +Sleep disturbance 0.3301007712729068 1.06769856941312 0.2856565039732039 1.0 0.6895225593384814 148 Q9H0U9,P04062,Q9H9B1,O75503,Q96ST3,P21359,P49591,P15311,Q9NQX3,O43464,P54802,P50897,P15586,Q7LGA3,Q9UBM7,O43709,Q96PZ0,Q14203,P39880,Q9UBB6,Q01105,Q96RR1,Q96N66,P31749,Q15056,Q10471,P35270,Q9UN37,Q9H9S5,O95831 30 +Abnormal vascular physiology 0.559922605631498 1.0673769044459136 0.2858016732906105 1.0 0.6895225593384814 55 Q69YQ0,P04062,O15460,P05067,Q9NZ08,P21359,Q8IZA0,P06280,Q93074,Q14108,P01889,Q9Y4U1,P00403,O43709,O96000,P31749,P51798,Q15056,O75844 19 +Omphalocele 0.592242821299693 1.066859021717553 0.2860355015937676 1.0 0.6897278319762354 16 Q8TD19,O15111,Q69YQ0,P62258,Q8NCM8,P98164,Q14739,Q9ULC3 8 +Neoplasm of the peripheral nervous system 0.5926392155912658 1.0610144063527307 0.2886833541526696 1.0 0.6949432157610499 18 P21359,P10644,P31749,O60333,Q07954 5 +Acute coronary syndrome 0.5940415819679248 1.0594706138916576 0.2893855054293743 1.0 0.6955771836691165 21 P04114,P06280,Q15056,P01889,Q9NZ08,O43709 6 +Neck muscle weakness 0.5914940910192102 1.0590040362730395 0.28959794151817 1.0 0.6955771836691165 17 Q99720,P07602 2 +Neoplasm by histology 0.3247494069826825 1.058465797830645 0.2898431357059969 1.0 0.6956535301597867 106 P21359,Q15555,Q8TD19,Q9UPY3,P62857,Q93063,P10644,Q15392,P31749,O60333,O60934,P29992,Q13126,P53634,Q99643,Q07954 16 +Abnormal aggressive impulsive or violent behavior 0.3250567590306514 1.0577406293335432 0.2901737067126366 1.0 0.6960866415036193 107 Q10713,Q9H9B1,O75503,Q96ST3,P49591,P17480,Q93074,P54802,Q8ND04,Q9UBM7,Q7LBC6,Q15125,Q96PZ0,P39880,O00462,Q9NQ11,Q01105,P35670,P19022,Q6IA86,Q9NUM4,P35270 22 +Limited hip movement 0.5902145546184077 1.056777632463266 0.2906130848393409 1.0 0.6967801832471684 16 Q7LGA3,Q93063,Q8TD16,Q969X5 4 +Disproportionate tall stature 0.5926702675830229 1.0543645118605602 0.29171606339326 1.0 0.6970318655551864 32 Q7LGA3,Q93074,O00754,P31749,Q8NCH0,Q96PZ0 6 +Eyelid myoclonus 0.5841506192222822 1.053906774131249 0.2919256011713411 1.0 0.6970318655551864 11 P00374,Q13510,Q01105 3 +Unusual infection by anatomical site 0.5886596569434851 1.0536407844642184 0.2920474092305918 1.0 0.6970318655551864 15 Q9NZ08,P01889,O15460,P02786 4 +Neoplasm of the male external genitalia 0.5853125187581509 1.0533739127873831 0.2921696555123274 1.0 0.6970318655551864 12 Q13423,P10644,P31749 3 +Abnormal emotion affect behavior 0.3140286901448352 1.053049267517406 0.2923184125611375 1.0 0.6970318655551864 231 Q10713,P07602,Q7KZN9,P17900,P04062,Q9H9B1,O75503,Q96ST3,P60866,Q9NZ08,P49591,P17480,Q5KU26,Q9Y5K6,Q93074,P06865,O43464,P61457,P54802,P01889,P50897,Q8ND04,Q8N183,Q9UBM7,Q13144,Q13510,O43567,Q7LBC6,Q15125,Q96PZ0,Q14203,P39880,O00462,Q9NQ11,Q01105,P35670,P54098,P19022,P10644,Q6IA86,P31749,Q9GZZ9,Q9NUM4,P29992,P35270,O95831 46 +Bulbar signs 0.5848175478641391 1.0509589740955971 0.2932774326860761 1.0 0.697863231379076 12 Q99720,P07602 2 +Abnormal upper motor neuron morphology 0.5820629004397704 1.050376796380046 0.2935449095039932 1.0 0.6980347412153932 10 Q99720 1 +Abnormal vitamin b12 level 0.5799998830386841 1.047414015947195 0.294908670144224 1.0 0.7004716290327343 9 Q9Y4U1,O43567 2 +Abnormality of refraction 0.3281112900119792 1.0461626254772047 0.2954859552993787 1.0 0.7004950791018503 156 O15460,Q9H9B1,P98164,Q96ST3,P51648,Q9UQR1,Q9H490,Q9H3S7,P61586,Q8ND04,Q15904,Q07021,Q8NCH0,Q7LGA3,Q15555,O43292,Q13555,Q9Y487,O94886,O43709,Q96PZ0,Q8N3R9,Q8WVQ1,O00754,P31749,Q15056,Q10471,P29992,Q9H9S5,Q99643 30 +Abnormal epiphyseal ossification 0.5905911988923592 1.044434692543098 0.2962843197138469 1.0 0.7009542808740348 20 Q9UBM7,Q99519,P56589,P08236,P10644,P40855,Q14739,Q15125 8 +Nausea and vomiting 0.3285839512049484 1.0438952203813738 0.2965338697906108 1.0 0.701146569443822 147 Q13277,P07602,Q04656,P42892,Q9NZ08,P38571,P21359,Q8IZA0,Q9Y6B6,P06280,P11117,O43464,P22695,Q13423,P01889,Q8N183,Q9UBM7,P23229,P00403,O60333,O43709,Q14203,Q9BQP7,P54098,Q93063,O96000,P31749,Q15056 28 +Abnormal pleura morphology 0.5909265845534707 1.0436053611669365 0.2966680114834545 1.0 0.701146569443822 21 Q9UPY3,P08236,Q92917,O15460,Q93063,P01889,Q9NZ08,Q8NCH0 8 +Aplasia hypoplasia involving bones of the lower limbs 0.387135810587755 1.0431883865972087 0.2968610510866689 1.0 0.7012453865964767 95 O15111,Q69YQ0,Q9BZK7,Q04656,Q8IWS0,Q9H173,P08069,Q96HY6,Q9H3S7,Q13620,Q7LGA3,Q9UBM7,Q13555,Q13510,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,Q93063,P10644,Q10471,O95831 27 +Abnormal fear anxiety related behavior 0.327670006606578 1.0426569789085307 0.29710718956294 1.0 0.701469469451809 121 Q69YQ0,P17900,Q9H9B1,O75503,P60866,P08069,O00192,P21359,P06280,O43464,Q7LGA3,P00403,O60333,O43709,Q96PZ0,Q14203,Q96RR1,P54098,P19022,P10644,O00754,Q15056,Q9NUM4,P29992,Q99643 25 +Lens subluxation 0.5699965967170951 1.041792211417707 0.2975080259255478 1.0 0.702058379754079 4 P29992 1 +Stenosis of the external auditory canal 0.5770197001439816 1.0404931348079294 0.2981108519336228 1.0 0.7031231029583973 8 Q93074 1 +Variable expressivity 0.4520046165820996 1.0397418112355707 0.2984598697200045 1.0 0.7033338745093102 83 Q9NR77,Q8TD16,P07602,P17900,Q9BUF5,P33993,Q70HW3,Q9Y263,Q13885,Q13510,P00403,P41227,Q6P4A7,P23258,Q15427,Q15125,P00374,Q8WVQ1,Q9BV79,P54098,O15121,P43034,O43707,Q9NUM4,P35270,Q9H9S5 26 +Macular purpura 0.587355786348739 1.0383489236549703 0.2991076394533487 1.0 0.7033338745093102 17 Q99519,Q9BZK7,P04062,P10644,P40763,Q8NCH0 6 +Diaphyseal thickening 0.5671707784114903 1.0383432349494957 0.2991102869381841 1.0 0.7033338745093102 3 P08236 1 +Eeg with spike wave complexes 0.5854797687472932 1.0379210097778475 0.2993068313165725 1.0 0.7033869807668948 15 O75503 1 +Ectopia pupillae 0.5690871385403582 1.0374957782001322 0.2995048622408514 1.0 0.7033869807668948 4 O96028 1 +Hypoplastic helices 0.5647683682502241 1.0373174369973448 0.2995879419915068 1.0 0.7033869807668948 2 P08754 1 +Photophobia 0.5825605323607296 1.0358378246990538 0.300277808031351 1.0 0.7046498966808578 40 P07602,O43395,P51648,P01889,Q9Y287,Q9NZ08,P48449,P04439 8 +Abnormality of the gingiva 0.563907184863168 1.0334143051550302 0.3014100548097413 1.0 0.7065917210074675 51 Q9UBM7,Q99519,Q9BZK7,O43909,P08236,P04062,Q14108,O00754,P16278,Q15392,P10644,Q15056,P40763,P53634 14 +Disproportionate short stature 0.5894589747186246 1.0326054443922386 0.3017885792872168 1.0 0.7067644657347598 30 Q7LGA3,Q9UBM7,Q9UHX1,Q8WVQ1,Q96HY6,P34059,O43909,Q32P28,P10644,Q15392,P16278,Q14739,Q15125 13 +Young adult onset 0.5805412753448826 1.0301079700496585 0.302959324281463 1.0 0.708432872765075 12 Q9NQ11,P07602 2 +Hypolipoproteinemia 0.5755588820456269 1.0260358165828785 0.3048747018072792 1.0 0.7117518564708112 9 P38571,Q9Y6B6,P04114 3 +Melanoma 0.587377151343268 1.0255419091721754 0.3051075613205023 1.0 0.7117518564708112 21 P53634,O60934,P31749,P29992 4 +Abnormal nervous system electrophysiology 0.319087669395707 1.0248093864299626 0.305453136591959 1.0 0.7117518564708112 194 P07602,P56589,Q9UBX3,O60313,Q96N67,Q9NVC6,O75503,Q8IWS0,O14773,P21359,P49591,P17480,P15311,Q14108,Q9H3S7,Q13620,P51797,P50897,Q8NC96,O43292,P62258,Q9Y263,Q9BQE5,P40855,P00403,O60333,O43567,Q9NWW5,O96028,Q99720,P48449,Q15125,Q99519,Q9UBB6,P54098,Q96N66,Q9GZZ9,Q9NUM4,Q6UWE0,Q9H9S5,O95831 41 +Diplopia 0.5858539442691024 1.0235202866421087 0.3060619131249222 1.0 0.7120968846765 19 P04062,O15460,O14773,P01889,Q13472,Q14671 6 +Abnormal pulmonary thoracic imaging finding 0.5846504536114489 1.0209615732743489 0.307272644890334 1.0 0.7134818499531692 18 P40763,P04062,Q13510,P01889 4 +Weak cry 0.574218160281093 1.0195871559942176 0.3079242989807818 1.0 0.7146371243112538 9 Q69YQ0,Q13510 2 +Oral ulcer 0.5686145443257522 1.0164367519645 0.3094214518259095 1.0 0.7162597659037151 6 P01889 1 +Moderate albuminuria 0.5624915311036649 1.0163320384920829 0.30947129680714 1.0 0.7162597659037151 3 P40763 1 +Diffuse alveolar hemorrhage 0.5701575678166333 1.015517527745358 0.3098591956874816 1.0 0.7162597659037151 7 P10644,P40763 2 +Addictive behavior 0.5701575678166333 1.015517527745358 0.3098591956874816 1.0 0.7162597659037151 7 P10644,P40763 2 +Oral cavity bleeding 0.5701575678166333 1.015517527745358 0.3098591956874816 1.0 0.7162597659037151 7 P10644,P40763 2 +Ecchymosis 0.5795513761584349 1.0138190921585188 0.3106690834105978 1.0 0.7169471323047291 14 Q8NCH0,P04062,P40763,P10644 4 +Stomatitis 0.5812872021991885 1.012464648655171 0.3113159411382671 1.0 0.7169471323047291 16 Q9BZK7,P10644,P01889,P40763,Q9NZ08 5 +Abnormality of the urinary system physiology 0.3079247568684146 1.0096359471818903 0.3126697406132659 1.0 0.7195283311283941 296 Q8TD19,Q13277,O15111,Q10713,Q9BZK7,P34059,Q99643,P04062,Q9UNF1,O15460,P16278,Q04656,P98164,Q9H9B1,Q9NZ08,P21359,P04066,P06280,P08236,Q14108,Q9NQX3,Q9Y697,O43464,P61457,Q13423,P54802,P01889,P15586,P11413,P10253,Q8NCH0,Q07021,Q8N183,P23229,Q8TAA9,P62258,Q5XKP0,Q9Y4U1,P40855,P00403,O60333,Q5JRA6,O43709,O00462,Q99519,P35670,P54098,P10644,O00754,O96000,Q15056,O60934,P40763,P46020,P29992,Q9H9S5,Q4J6C6 57 +Genu valgum 0.5738298140446754 1.0078064555901425 0.313547386160391 1.0 0.7208325382378449 43 P21359,Q7LGA3,P34059,P08236,Q93063,O00754,P16278,Q9NX62,Q15056 9 +Decreased ldl cholesterol concentration 0.5643928016230166 1.005689770216912 0.3145648256128792 1.0 0.7225999334334086 5 Q9Y6B6 1 +Abnormal skin morphology of the palm 0.3594637915392222 1.0055588357332548 0.3146278338585404 1.0 0.7225999334334086 99 P07858,Q69YQ0,Q9BZK7,P56589,Q9H9B1,Q96ST3,Q14739,Q93074,O43909,Q9NX24,Q14126,P53634,Q8NCH0,Q9Y263,Q9Y487,P40855,O96028,Q9UHX1,P09493,P31749,Q99643 21 +Abnormal dlco 0.557686633225143 1.004133392647986 0.3153143218776892 1.0 0.7238180745281411 2 O95453 1 +Petechiae 0.5760256083801777 1.002128016262096 0.3162817683417362 1.0 0.7254237210388812 13 Q99519,Q9BZK7,P04062,P10644,P40763 5 +Diffuse cerebral atrophy 0.5795374499392888 0.9993883754410416 0.3176065888557602 1.0 0.7256851945946129 17 Q10713,Q9NQ11,P07602,P16278,Q9NVC6,O75787 6 +Aphthous ulcer 0.5667652037989239 0.9993467154742476 0.317626762591362 1.0 0.7256851945946129 7 P01889 1 +Periodontitis 0.5725810055636816 0.9977854304759024 0.318383416547854 1.0 0.7256851945946129 11 Q5JRA6,P53634,Q9NX24 3 +Narrow mouth 0.4874162879794346 0.9975962676605598 0.318475171662721 1.0 0.7256851945946129 74 Q7LGA3,Q8WVQ1,P62258,Q93074,O43909,P04062,Q15392,Q9NX62,P31749,P08069,Q8NCH0,Q96PZ0 12 +Vertebral hypoplasia 0.5709531769696785 0.9967202266903532 0.3189003289642553 1.0 0.7259405132092548 10 Q14739,P10644,Q8TAA9,P16278 4 +Severely reduced visual acuity 0.5618027892402322 0.9934432501417424 0.3204939933715125 1.0 0.7261094688356283 5 Q13277 1 +Sepsis 0.5810310993387676 0.9909197445504984 0.3217247703057793 1.0 0.7273709214568008 22 P42892,O43567,P01889,P02786 4 +Sparse and thin eyebrow 0.5732342340614127 0.9884954363511196 0.3229100683891768 1.0 0.7293163188165758 13 P21359,P48449,Q96EK5,P62857 4 +Pulmonary hemorrhage 0.5660423963685747 0.9879377828505536 0.3231831198875379 1.0 0.7293163188165758 8 P10644,P40763 2 +Ureteral obstruction 0.565111391565958 0.9834894719529096 0.3253665943471961 1.0 0.7333660203319818 8 Q9UBM7 1 +Hallucinations 0.5613686783378513 0.9813789106900188 0.3264059220705058 1.0 0.7347302236121045 48 Q9NQ11,P07602,P04062,P05067,O00754,O75503,Q9NWW5,P50897 8 +Abnormal lung lobation 0.5726371787523 0.9798950707795132 0.3271379163733481 1.0 0.7360206298996678 14 Q9UBM7,O15111,P31749,Q14739,O00192 5 +Cranial asymmetry 0.5607935685432887 0.9793249738170222 0.3274194346031267 1.0 0.7362967595803582 6 O96028,P40855 2 +Malar prominence 0.5543901536885678 0.9783052540884708 0.3279233720890331 1.0 0.7370275300433707 3 O60934 1 +Hypertrophic cardiomyopathy 0.3220400385815044 0.9780243391902111 0.3280622863941163 1.0 0.7370275300433707 116 Q8TD19,Q7KZN9,Q96IX5,P16278,P21359,P06280,Q9C0B1,Q9Y697,Q13423,P54802,P01889,P15586,Q8N183,P10253,P13473,Q5XKP0,P00403,Q9H2U2,O43709,P09493,O96000,Q15056 22 +Increased sulfur amino acid level in urine 0.5604028103786893 0.9774735740257364 0.3283347542522257 1.0 0.737282448168315 6 Q9Y4U1 1 +Cryptorchidism 0.3164510262291458 0.9747953970557914 0.3296617608062182 1.0 0.7395460013828902 193 Q69YQ0,Q9BZK7,P56589,Q9H0U9,Q8N6M0,Q9H9B1,Q9H1A4,Q8IWS0,Q96ST3,Q6W2J9,O00192,P21359,Q5KU26,Q9C0B1,Q9Y4P3,Q93074,Q9BXW9,Q9H3S7,Q13620,Q13423,Q8NFV4,Q9H2M9,Q8WYQ5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,P60953,Q9Y487,P40855,P41227,O75381,Q7LBC6,O43505,O96028,O43709,P63241,P48449,Q96PZ0,Q8N3R9,Q15125,Q9ULC3,Q8NCM8,O15078,P19022,Q93063,O15344,P10644,Q15056,Q9H9S5 51 +Diminished motivation 0.5786656452000482 0.974066285851756 0.3300236279641662 1.0 0.7395685904366401 25 Q9NQ11,P06865,P17900,O43464,P04062,Q9H9B1,Q9NUM4 7 +Abnormal morphology of the great vessels 0.3179281527445792 0.9711569885778724 0.331470108653271 1.0 0.740671784125095 182 Q8TD19,O15111,Q69YQ0,P51571,P04062,O15460,Q9UBS4,Q15392,Q9H9B1,P42892,P60866,Q6W2J9,O00192,Q9Y3D3,Q9UQR1,P21359,P46783,P62857,Q9C0B1,Q9Y4J8,Q9Y4P3,Q93074,Q9BXW9,Q9H3S7,P47985,P01889,Q8NFV4,Q8ND04,Q96MF7,Q8WYQ5,Q7LGA3,Q9UBM7,P55263,P04114,P60953,P40855,P61313,Q7LBC6,Q9ULC3,Q15427,O43709,Q96PZ0,Q8N3R9,Q9UHX1,P19022,Q93063,P31153,P51798,Q15056,O75844 50 +Neoplasm of the tracheobronchial system 0.552808257531952 0.970893792410764 0.3316011696880951 1.0 0.740671784125095 3 Q9UPY3 1 +Elevated pulmonary artery pressure 0.5781275180904977 0.970525717064096 0.3317845124829728 1.0 0.7406867827069009 26 P21359,Q8IZA0,Q93074,Q9Y4U1,P04062,Q14108,O96000,P00403,P51798,P01889,O75844 11 +Osteopenia 0.5026554548627146 0.967537288109827 0.333275510065077 1.0 0.7409013759822778 69 P21359,O43292,Q13277,Q13126,Q9H490,P07602,Q9Y487,Q04656,P04062,Q14108,Q32P28,O00754,P10644,Q15056,P40763,Q5JRA6,O43709 17 +Abnormality of earlobe 0.5767858836754441 0.9635358000797978 0.3352787072419625 1.0 0.7430111468598087 26 Q7LGA3,Q9BZK7,Q96N67,Q9H9B1,Q15392,Q8IWS0,O00192,P10586 8 +Abnormality of lower limb epiphysis morphology 0.5738745899652347 0.963327483022248 0.3353832054180463 1.0 0.7430111468598087 19 Q7LGA3,Q8WVQ1,O43909,Q04656,Q9H173 5 +Peripheral arterial stenosis 0.5511285486048708 0.9630294473697064 0.3355327456382229 1.0 0.7430111468598087 3 P04114 1 +Abnormality of fluid regulation 0.3193717348013582 0.9607285725439332 0.3366886608549271 1.0 0.7439548119265794 173 Q8TD19,Q13277,Q04446,P04062,P16278,Q9H1A4,Q14739,P60866,Q9P2R3,Q9NZ08,Q9Y3D3,P26358,P46783,P62857,Q9Y5K6,P06280,P28070,Q9Y4P3,Q14108,P08236,P50213,P01889,Q8NFV4,Q9UBM7,Q15555,P10619,P60953,Q9Y263,Q9Y4U1,Q7LG56,Q13510,P61313,O43567,O43709,Q15125,P04439,Q99519,Q99829,Q8NCM8,P35670,P54098,P52565,P10644,Q96RR1,O96000,P31749,Q15056,P40763 48 +Parkinsonism 0.5747936569557145 0.959946855889985 0.33708196244506 1.0 0.7439548119265794 33 Q9NQ11,P07602,Q96RR1,P54098,P04062,O43464,P05067,P61457,Q9NUM4,O75787,Q99720,Q14203 12 +Papule 0.5742444471348703 0.9563263900915636 0.3389073610914948 1.0 0.7466521371017538 22 P21359,P31749,P01889,P40763,Q07954 5 +Abnormality of skin adnexa physiology 0.557231983344467 0.9562455576309844 0.3389481881818399 1.0 0.7466521371017538 48 P21359,P07858,P04066,P06280,Q9Y263,O15460,Q13620,P07686,O60333,P51797,P01889,P35270,Q9NX24,Q99643 14 +Retinal degeneration 0.5209526243712688 0.9556802050116776 0.3392338263239682 1.0 0.7467268105325984 63 Q7LGA3,P04114,P04062,Q13510,O00754,O75503,O14773,Q9NWW5,P50897,Q96PZ0 10 +Upper eyelid coloboma 0.5470640306875189 0.954517902257868 0.3398215518169438 1.0 0.747510690595431 2 Q6NUK1 1 +Abnormal femoral head morphology 0.5726195115586266 0.9480569477433078 0.3431004638302029 1.0 0.7498301697538162 22 Q7LGA3,Q8WVQ1,O43909,Q04656,P16278,Q9H173 6 +Macroscopic hematuria 0.54558866922397 0.9476446622623996 0.3433103812252858 1.0 0.7498301697538162 2 P07741 1 +Uric acid nephrolithiasis 0.54558866922397 0.9476446622623996 0.3433103812252858 1.0 0.7498301697538162 2 P07741 1 +Thromboembolism 0.5520932772063049 0.947643177692575 0.3433111372503101 1.0 0.7498301697538162 5 P10644 1 +Albuminuria 0.551784689187638 0.9461907072305472 0.3440513250540791 1.0 0.7498301697538162 5 Q5JRA6,P40763 2 +Male reproductive system neoplasm 0.5688054798479338 0.9460754301425304 0.3441101145646152 1.0 0.7498301697538162 17 Q13423,P10644,O60934,P31749 4 +Follicular thyroid carcinoma 0.5489637771550808 0.9427719356705696 0.3457975694197563 1.0 0.7520934940897798 4 P31749 1 +Intestinal polyp 0.5717886134598171 0.9416267612514552 0.3463837635825908 1.0 0.7521993609192114 23 P42892,Q04656,Q9UPY3,P31749 4 +Abnormal arterial physiology 0.5724597351407058 0.9409128295225848 0.3467495324305831 1.0 0.7521993609192114 29 P06280,Q9Y4P3,P05067,O15460,P31153,Q15056,O75844,Q14739,P01889,Q9NZ08,O43709 11 +Severe hearing impairment 0.5441133077604116 0.9407762275926644 0.3468195457505443 1.0 0.7521993609192114 2 Q06124 1 +Anterior open bite malocclusion 0.5441133077604116 0.9407762275926644 0.3468195457505443 1.0 0.7521993609192114 2 P08754 1 +Infantile onset 0.3159990353074771 0.9398810036876688 0.3472786023675083 1.0 0.7524910650365122 183 P07602,Q96N67,O75787,O00584,Q9H173,P38571,Q14574,Q9Y6B6,Q5JPH6,P62857,P06865,Q9NQX3,Q70HW3,Q15904,O43292,Q9Y4U1,P07686,Q5JRA6,Q9UDY2,Q9UBB6,Q93063,P31749,P40763,P35270,O95831 25 +Cardiac diverticulum 0.5499267074828978 0.9374499900807236 0.3485271368545484 1.0 0.7537874690273045 5 P43246,P52701,P60866 3 +Abnormal left ventricular outflow tract morphology 0.5470918216710934 0.9340006806505644 0.3503035418914564 1.0 0.7551822427474032 4 O60566,Q15645,Q06124 3 +Subvalvular aortic stenosis 0.5470918216710934 0.9340006806505644 0.3503035418914564 1.0 0.7551822427474032 4 O60566,Q15645,Q06124 3 +Abnormal dermoepidermal junction morphology 0.547020894967233 0.9336685046516704 0.3504749161941798 1.0 0.7551822427474032 4 P23229,P15924 2 +Abdominal distention 0.5705321935263648 0.9304611210631027 0.3521323851390074 1.0 0.7566556529715985 27 P23229,Q13277,Q9Y6B6,P07602,Q96HY6,P54098,P04062,Q7LG56,P38571 9 +Abnormal bronchoalveolar lavage fluid morphology 0.5417527294187171 0.929797118807094 0.3524761383885244 1.0 0.7566556529715985 2 P53621 1 +Slow saccadic eye movements 0.5598737908852625 0.9297505265191794 0.3525002671366706 1.0 0.7566556529715985 12 Q8IV08,Q9NQ11 2 +Abnormality of femur morphology 0.4747926918221778 0.9291968919678608 0.3527870578626333 1.0 0.7566556529715985 75 Q8TD19,P07602,P34059,Q04656,P04062,P16278,Q14739,Q9H173,P04066,Q96HY6,P06280,O43909,Q96MW5,Q7LGA3,Q9Y487,Q32P28,Q9ULC3,Q9UHX1,Q8WVQ1,Q93063,O00754,P51798,O75844,O95831 24 +Abnormal aortic valve physiology 0.5638793090055992 0.9291221508857264 0.3528257861333104 1.0 0.7566556529715985 40 Q9UHX1,Q8TD19,P04114,Q9Y4P3,P04062,O00754,P31153,P16278,Q9H9B1,Q15056,O75844,P01889,Q6W2J9,Q9NZ08,O43709,Q15125 16 +Abnormal thumb morphology 0.3190485657623291 0.9289801925511922 0.3528993514889265 1.0 0.7566556529715985 118 Q8TD19,Q04656,Q8N6M0,Q96ST3,P42892,P60866,Q6W2J9,P46783,P62857,Q9Y4P3,Q93074,O43909,Q9BXW9,Q9H3S7,Q92917,Q8NFV4,Q8NCH0,Q7LGA3,Q9UBM7,P60953,P61313,P41227,O96028,Q9ULC3,Q15427,O43709,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,Q8NCM8,O15078,Q15056 33 +Chest pain 0.5669965845677194 0.928889963679702 0.3529461147519495 1.0 0.7566556529715985 19 P21359,P19022,Q93063,P10644,O60333,P01889,Q99643 7 +Generalized hypotonia 0.2939614060966528 0.9287009413309752 0.3530440927953029 1.0 0.7566556529715985 371 Q69YQ0,Q10713,P07602,Q9UBX3,Q7KZN9,Q04446,O15118,P17900,Q04656,Q8N6M0,Q9H9B1,Q8IWS0,Q9H173,Q96EK5,Q9UQR1,Q5KU26,Q93074,P06865,O43909,P11117,Q9NQX3,O43464,P61457,P51797,P50897,Q70HW3,Q14671,P10253,Q8NCH0,Q8N183,Q9UBM7,Q15555,O43292,Q13144,Q13555,Q9BWD1,Q9Y487,Q5XKP0,Q9Y4U1,P40855,P15291,P61916,Q6P4A7,O43567,Q9H2U2,Q7LBC6,O96028,Q15125,Q96PZ0,P00374,O00462,P39880,Q99519,Q8WVQ1,Q9UBB6,Q01105,Q96RR1,P54098,Q93063,O00754,Q96N66,P51798,Q9GZZ9,Q9NUM4,O14949,Q10471,Q9H9S5,O95831,Q4J6C6 69 +Long palm 0.5433884297520584 0.926868468488443 0.3539948303077465 1.0 0.7575871402246231 3 Q9BZI7,P16435 2 +Neoplasm of fatty tissue 0.5592589667957916 0.9267782237624544 0.354041693523131 1.0 0.7575871402246231 12 Q8TAA9,P31749,P29992 3 +Cachexia 0.567127512260202 0.9260174552750362 0.354436909050678 1.0 0.7580830015073774 20 P31749,P04062,Q99720,P07602 4 +Supernumerary nipple 0.5575537848015057 0.9252369619037446 0.3548426610062778 1.0 0.7586009308834072 11 Q7LGA3 1 +Recurrent bacterial infections 0.5651740738228821 0.923744375096016 0.3556194223420394 1.0 0.759083436707621 18 P53634,Q15904,O00754 3 +Abnormality of the radial head 0.5508180671991376 0.9236165212288464 0.3556860089723352 1.0 0.759083436707621 7 O43909,P10644 2 +Abnormality of pulmonary circulation 0.5683335191799235 0.9227067485607634 0.3561600480180351 1.0 0.7592868293988708 32 P21359,Q8IZA0,Q93074,Q9Y4U1,P04062,Q14108,O96000,P31749,P00403,P51798,O75844,P01889,Q9NZ08 13 +Rhabdomyosarcoma 0.5554945236595865 0.9224196704257914 0.3563097133430974 1.0 0.7592868293988708 10 P21359,O60934 2 +Neoplasm of striated muscle 0.5554945236595865 0.9224196704257914 0.3563097133430974 1.0 0.7592868293988708 10 P21359,O60934 2 +Subcortical heterotopia 0.5455421054653917 0.916854960199864 0.3592186481400461 1.0 0.7637307984527253 5 P23258,P43034 2 +Subcortical band heterotopia 0.5455421054653917 0.916854960199864 0.3592186481400461 1.0 0.7637307984527253 5 P23258,P43034 2 +Submucous cleft of soft and hard palate 0.5667651670433037 0.912534476434316 0.361487429145406 1.0 0.7663372588667783 25 Q7LGA3,Q15392 2 +Periauricular skin pits 0.5561925523773588 0.9119676039462205 0.3617857716153536 1.0 0.7663372588667783 12 Q9ULC3,O96028,Q07954 3 +Sparse eyelashes 0.5627650325433301 0.9117747302364938 0.3618873153669057 1.0 0.7663372588667783 18 P21359,Q14574,O75844,Q15427,Q15125,P48449 6 +Iris coloboma 0.5624311907253059 0.9102076459419334 0.362713012626116 1.0 0.766961766688162 38 Q9UBM7,Q9UHX1,Q7Z3E5,Q10713,Q9Y467,O96028,P98164,Q96ST3,P41227,Q6W2J9,O43505,Q96EK5,Q9H9S5,Q7Z392 14 +Optic disc coloboma 0.5461109119357397 0.9099794655414624 0.3628333392671106 1.0 0.766961766688162 6 Q10713,Q9Y467,Q6W2J9 3 +Pseudoarthrosis 0.5439233002609005 0.90926321931082 0.3632112005515 1.0 0.766961766688162 5 P21359 1 +Pseudohypoaldosteronism 0.5373266450280426 0.9092478122178524 0.3632193313882259 1.0 0.766961766688162 2 Q9H4A3 1 +Hyperchloremic acidosis 0.5373266450280426 0.9092478122178524 0.3632193313882259 1.0 0.766961766688162 2 Q9H4A3 1 +Cardiac valve calcification 0.5415463306695275 0.9080659988670406 0.3638433531404383 1.0 0.7672312999146033 4 P04062 1 +Mitral valve calcification 0.5415463306695275 0.9080659988670406 0.3638433531404383 1.0 0.7672312999146033 4 P04062 1 +Abnormality of blood volume homeostasis 0.5411815597496691 0.906362797382609 0.36474385716064 1.0 0.7684312883479727 4 Q13277,P40763 2 +Short chin 0.5533099019357499 0.9048388990241724 0.3655507406008373 1.0 0.7691208829099685 11 O43567 1 +Microretrognathia 0.5604363973486811 0.9046696798609548 0.3656404085311511 1.0 0.7691208829099685 17 Q9UHX1,Q8WVQ1,Q96ST3,Q8NCH0,Q96MF7,Q15427,Q15125 7 +Shyness 0.5383707201888955 0.9035023526183372 0.3662593402025553 1.0 0.7691208829099685 3 Q06787,P09884 2 +Spina bifida occulta 0.5613289698433411 0.9005948337148872 0.367803782475079 1.0 0.7713731973482323 19 Q9UHX1,Q8TD19,Q8TAA9,Q9Y4P3,Q15056,Q9ULC3,O43709 7 +Elevated gamma glutamyltransferase level 0.5419050721630042 0.8998078633192074 0.3682225090074897 1.0 0.7719022487647966 5 P38571 1 +Chronic infection 0.5521855949824134 0.8994426960693293 0.3684169057804403 1.0 0.771960773657434 11 P40763,P10644,Q9BZK7 3 +Fasciculations 0.5594187775272862 0.8982611955935249 0.3690463150582612 1.0 0.7724361094157485 39 Q8TD16,P07602,P06280,Q9H0U9,Q9NQX3,Q13510,P07686,Q9NUM4,Q6UWE0,O95831 10 +Abnormal enzyme coenzyme activity 0.3121089833996491 0.897813341846136 0.3692850705306572 1.0 0.7724361094157485 193 Q9Y6B6,P10619,P07602,O43505,P35670,P38571,O15118,P04062,Q13510,O00754,P07686,P16278,P28070,P61916,P01889,Q9H173,Q15904,P10253 18 +Abnormality of urine calcium concentration 0.5567615326643028 0.896722065199921 0.3698672434388443 1.0 0.7725560395612259 15 P35670,Q9Y4P3,Q9UNF1,Q15056,P29992,O43709 6 +Abnormal magnesium concentration 0.5431539466929375 0.8960760711622366 0.3702121361109793 1.0 0.7729282643613739 6 P61457 1 +Abnormal metacarpal morphology 0.5617930951347002 0.8947827729876503 0.370903221001257 1.0 0.7738001048073699 35 Q8WVQ1,P34059,P08236,P10644,Q93063,P16278,Q9NX62,Q9H173 8 +Constipation 0.337909403240214 0.8946700846563465 0.3709634748731472 1.0 0.7738001048073699 101 P04062,Q04656,Q8N6M0,P42892,P60866,Q93074,O43464,Q13423,Q8NCH0,Q7LGA3,Q9UBM7,Q8TAA9,P00403,O43709,Q96RR1,P54098,Q93063,Q15056,Q10471,Q99643 20 +Erythema 0.5610334478524296 0.8921617639076748 0.3723062333896738 1.0 0.7752594739577352 21 P07858,P51648,P01889,P40763,Q15125,Q07954 6 +Acantholysis 0.5402272578119481 0.8919557108547748 0.3724166717925512 1.0 0.7752594739577352 5 P15924,P01889 2 +Abnormal morphology of the musculature of the neck 0.5545456555159064 0.8915851210977164 0.3726153481355223 1.0 0.7752594739577352 14 Q99720 1 +Soft tissue sarcoma 0.561666111356803 0.8911784704300623 0.3728334325912765 1.0 0.7752594739577352 34 P21359,Q9UPY3,P10644,Q15392,P31749,O60934,Q13126,Q07954 8 +Bowing of the legs 0.5141261871896541 0.8877604194639229 0.3746696378720089 1.0 0.77628271583493 62 Q9NR77,Q8TD19,P34059,Q04656,P16278,Q9H1A4,Q6W2J9,P21359,Q96HY6,Q9Y4P3,P08236,Q7LGA3,Q32P28,Q9NX62,Q9ULC3,O43709,Q8WVQ1,Q8NCM8,Q93063,O00754,P51798,Q15056,Q13126 23 +Abnormal ilium morphology 0.5606088492640028 0.8871225236101945 0.3750129388304823 1.0 0.77628271583493 22 Q8TAA9,P34059,O43909,Q04656,O00754,P16278,P01889,O95831 8 +Upgaze palsy 0.5412372645591045 0.8870767142877207 0.3750375998391093 1.0 0.77628271583493 6 Q96RR1,Q9NQ11 2 +Aplasia involving bones of the extremities 0.5369760673353124 0.8867523822697437 0.3752122295293918 1.0 0.77628271583493 4 Q04656,Q8NCM8 2 +Chorioretinal coloboma 0.5476459282481703 0.884906878817666 0.3762068576733415 1.0 0.7768754274256645 10 P41227,Q10713,P31749,Q6W2J9 4 +Abnormal iliac wing morphology 0.5518583764860795 0.8846286713271029 0.3763569377270284 1.0 0.7768754274256645 13 Q8TAA9,P34059,Q04656,P16278,O95831 5 +Increased ldl cholesterol concentration 0.5437754651677666 0.8820558355766538 0.3777466135705389 1.0 0.77782696174107 8 P38571 1 +Hyperlipoproteinemia 0.5437754651677666 0.8820558355766538 0.3777466135705389 1.0 0.77782696174107 8 P38571 1 +Epiphyseal dysplasia 0.5418773741501062 0.8814164551420355 0.3780924545128679 1.0 0.7781689798385124 7 Q8WVQ1 1 +Abnormal paranasal sinus morphology 0.5597714453251424 0.8803627210281573 0.378662844797953 1.0 0.7789971656291518 23 P21359,P04066,P28070,P10644,O00754 5 +Puberty and gonadal disorders 0.3170311681671143 0.8791053039945784 0.3793441821688428 1.0 0.7797069914525373 161 O60313,P04062,Q9H9B1,Q9H1A4,Q8IWS0,Q9H173,P21359,P06280,O43395,Q9Y4P3,Q14108,Q9BXW9,Q9H3S7,Q13620,P50213,Q13423,Q8NFV4,Q9H2M9,Q7LGA3,Q9UBM7,Q15555,Q13144,Q7LG56,P00403,Q5JRA6,O96028,Q9ULC3,O43709,P63241,P48449,Q96PZ0,Q8N3R9,Q9BQP7,Q96RR1,P54098,Q93063,P10644,P31749,Q15056,P40763,Q9UN37,O75844,Q4J6C6 43 +Abnormal pyramidal sign 0.31683001718948 0.8756172849715019 0.3812381254922041 1.0 0.7813553643576462 126 P07602,Q04446,O60313,P17900,P51648,O14773,P60866,O75787,Q9NZ08,P07384,P17480,P04066,Q93074,P01889,Q9Y263,O94886,Q99720,P41440,Q9NQ11,O00754,Q9NUM4,Q9H9S5,O95831 23 +Ankyloblepharon 0.5384450098925676 0.8739851133504676 0.3821263608426983 1.0 0.7813553643576462 6 O15111,Q6W2J9 2 +Abnormal pulmonary interstitial morphology 0.5590948694133803 0.8716993564419695 0.3833724114464223 1.0 0.781949204189598 31 Q8IZA0,P04062,Q13510,Q14108 4 +Enlarged thorax 0.5536467787449311 0.8712107606682703 0.3836390855146292 1.0 0.781949204189598 17 P04066,P08236,Q92917,Q32P28,Q14739,Q6W2J9,O75844 7 +Delusions 0.5542019789179159 0.8693518412844716 0.3846547155896322 1.0 0.7821508542903951 18 O00754,P07602 2 +Metrorrhagia 0.5410664814322377 0.8692605201177994 0.3847046517115295 1.0 0.7821508542903951 8 P10644,P40763 2 +Productive cough 0.5410251994541337 0.869065703487532 0.3848111943374073 1.0 0.7821508542903951 8 P10644,P40763 2 +Pain in head and neck region 0.5370877658229857 0.867629992777704 0.38559692173299 1.0 0.7821508542903951 6 P31749 1 +Asymmetric growth 0.5518069624561415 0.8671778026328962 0.3858445965465493 1.0 0.7821508542903951 16 Q93063,Q15125,P31751,P31749 4 +Hyporeflexia of upper limbs 0.5298361799597876 0.863918007266291 0.3876329339634239 1.0 0.7827226405719584 3 O75787 1 +Thick hair 0.539928118704457 0.8638903109091931 0.3876481499152704 1.0 0.7827226405719584 8 Q04656 1 +Ectopic calcification 0.5044045245888588 0.8609442634707083 0.3892687413838263 1.0 0.7851409977367562 64 P56589,O60313,Q04656,P05067,P04062,O00584,P38571,P08236,P53634,Q9UBM7,P04114,P40855,P00403,Q15125,Q99519,P35670,P10644,P29992,O75844 19 +Broad based gait 0.5562541754009735 0.8602883048368929 0.3896301380586073 1.0 0.7851868536191926 24 Q93074,P04062,Q93063,Q9NUM4,O14773 5 +Aplasia hypoplasia involving the skeleton 0.304089466928883 0.858034539516171 0.390873391529815 1.0 0.7863253433942526 318 Q8TD19,O15111,Q69YQ0,Q8TD16,Q9BZK7,P34059,P56589,P04062,Q04656,Q15392,P16278,Q8IWS0,Q96ST3,O75787,Q14739,P60866,Q9H173,P08069,O00192,Q96EK5,Q969X5,P21359,P04066,P62857,Q96HY6,Q93074,P08236,O43909,Q92917,Q9H3S7,Q13620,Q14671,Q8ND04,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,Q13555,Q9Y297,Q9Y263,Q32P28,Q13510,P40855,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,O43709,P63241,Q8N3R9,Q9UHX1,Q8WVQ1,Q93063,P10644,P31749,P51798,Q15056,Q10471,O60934,O75844,Q9H9S5,O95831 67 +Autistic behavior 0.3084334454339402 0.8558064390667313 0.3921048529812798 1.0 0.7870371908964466 200 Q69YQ0,Q96N67,Q8N6M0,Q9H9B1,O75503,Q96ST3,O00192,P21359,P49591,P17480,P15311,Q5KU26,Q93074,O43909,Q9NQX3,Q9H3S7,O43464,Q8N183,Q7LGA3,Q8NC96,Q9UBM7,Q5XKP0,Q7LBC6,O43709,P63241,P48449,Q96PZ0,Q8N3R9,Q9UHX1,P39880,Q9UBB6,Q01105,O75489,Q96RR1,P19022,Q93063,P10644,Q96N66,P31749,O96000,Q9GZZ9,Q15056,Q9NUM4,Q10471,Q99643 45 +Absent facial hair 0.5407202361221702 0.8519503009937734 0.3942416767954302 1.0 0.7889938089341433 10 P15924,O75844,Q07954,Q9H1A4 4 +Axial muscle weakness 0.5313940820716765 0.8507524973878081 0.394906854253148 1.0 0.7898056955071611 5 Q8TD16 1 +Abnormal femoral neck head morphology 0.533806973724202 0.8461934356707197 0.397444843305716 1.0 0.793691532475713 51 Q7LGA3,P04066,Q8WVQ1,Q96HY6,P34059,Q9Y487,O43909,Q04656,Q93063,O00754,P16278,O75844,Q14739,Q9H173,Q9ULC3,O95831 16 +Abnormal acetabulum morphology 0.5517838522470737 0.8457297665947665 0.3977035135930689 1.0 0.7938662042751014 21 Q8WVQ1,O43909,P08236,P16278,Q969X5 5 +Malnutrition 0.5358896947444827 0.8448722306761139 0.3981821804293395 1.0 0.794310732446567 8 P38571,Q9Y6B6 2 +Left ventricular hypertrophy 0.5539426736688139 0.8441283661549409 0.3985976781742149 1.0 0.7946248640128264 27 P06280,Q9Y4J8,Q96RR1,P54098,Q9H9S5,P10253,P00403,O75787,Q07021 9 +Noncompaction cardiomyopathy 0.5276055506347698 0.8432456261568336 0.3990910857057896 1.0 0.794770444691311 4 P21912,Q9Y4J8,Q15233 3 +Adducted thumb 0.5534096760899876 0.8424282554360617 0.3995482826898908 1.0 0.794770444691311 26 Q92917,Q04656,P42892,Q15056,O43709,Q8NCH0 6 +Delayed ability to sit 0.5455445807867628 0.8421086042846522 0.3997271654896499 1.0 0.794770444691311 15 Q10713,O43909,P43034,Q10471,P10253 5 +Abnormal urine protein level 0.5071296494150604 0.8396367192576714 0.4011121046131372 1.0 0.7962143960150331 62 P21359,Q99519,P06280,P35670,Q9Y4U1,P04062,Q14108,Q9UBS4,P98164,P00403,O60333,Q15056,P40763,Q5JRA6,O43709,Q99643 16 +Ventricular preexcitation 0.5329036258635647 0.8392943311549868 0.4013041635636338 1.0 0.7962547738316518 7 P10253 1 +Cirrhosis 0.5458606843123442 0.8384033174568315 0.4018042269003326 1.0 0.7969059880824817 42 Q15904,Q10713,Q04446,Q9UDY2,P35670,P54098,P04062,Q14108,Q7LG56,Q14739,O75787,Q9NX24,P38571,P11717 14 +Complex febrile seizure 0.5199173797580534 0.8289639427812178 0.4071248108033174 1.0 0.8041852058410827 2 Q9H9E3 1 +Low back pain 0.5199173797580413 0.828963942781162 0.4071248108033489 1.0 0.8041852058410827 2 P54886 1 +Hypomimic face 0.5414953262866726 0.8284265254403437 0.407428989611049 1.0 0.8041852058410827 14 Q9NQ11,Q9Y263,P54098,Q96RR1,P04062,O75787,P35270 7 +Long thorax 0.5219960118163164 0.8277557115030146 0.4078088610960395 1.0 0.8041852058410827 3 Q6W2J9 1 +Increased circulating antibody level 0.545760833231945 0.8277491875830272 0.4078125565263637 1.0 0.8041852058410827 18 Q14108,P04062,P40763,P28070 4 +Abnormality of the wrist 0.5476346850853474 0.8275905218299136 0.4079024378128588 1.0 0.8041852058410827 38 Q8WVQ1,P34059,O43909,Q04656,Q13510,Q93063,P16278,P31749,O95831,Q15125 10 +T cell lymphoma 0.5260176878365024 0.825797154317157 0.4089191686296658 1.0 0.8058470824206376 5 O60934,Q05655 2 +Aplasia hypoplasia of the spleen 0.5256749367281195 0.8242096693968249 0.4098204338087825 1.0 0.806937304276571 5 O15078,Q8TD19 2 +Congenital diaphragmatic hernia 0.5494738365526745 0.8221954042535723 0.4109656939631498 1.0 0.8085056949118056 26 Q9UBM7,P62857,P98164,Q7LBC6,O96028 5 +Downslanted palpebral fissures 0.3139320246756098 0.8179077589400849 0.4134098595771505 1.0 0.8115925143349901 146 Q69YQ0,P56589,Q04656,Q8N6M0,Q15392,P98164,Q96ST3,O00192,Q96EK5,Q9UQR1,P21359,P62857,Q93074,Q9H3S7,Q13620,Q8NCH0,Q7LGA3,Q8NC96,Q9UBM7,Q15555,P62258,Q9Y487,O96028,Q15427,P63241,Q96PZ0,Q15125,Q8N3R9,P19022,P31749,Q9GZZ9,Q10471,O75844 33 +Abnormal femoral neck morphology 0.5406286532408958 0.8147888165530087 0.415193203507634 1.0 0.8133717298964508 43 P04066,Q8WVQ1,Q96HY6,P34059,Q9Y487,O43909,Q04656,Q93063,O00754,P16278,O75844,Q9H173,Q9ULC3,O95831 14 +Telangiectasia 0.54582488848168 0.8137253372721789 0.4158023157094743 1.0 0.8142210041996759 37 Q8IZA0,Q99519,P10619,P06280,P31749 5 +Colorectal polyposis 0.5337917079941449 0.8116996620969991 0.4169639882948737 1.0 0.8150008211586149 11 Q9UPY3,P31749 2 +Coloboma 0.5243091663733043 0.8111096566923562 0.417302700765767 1.0 0.8150008211586149 53 Q9UBM7,Q9UHX1,Q7Z3E5,Q69YQ0,Q10713,Q9Y467,Q9Y4U1,O96028,P31749,P98164,Q96ST3,P41227,Q9H2M9,Q6W2J9,O43505,Q96EK5,Q9H9S5,Q7Z392 18 +Abnormal sweat gland morphology 0.5179360862274165 0.809114987238063 0.4184490083183938 1.0 0.8166448028503334 3 O15111 1 +Alopecia totalis 0.5235798083252352 0.8047135435710784 0.420985002248595 1.0 0.8202388059245227 6 Q9H1A4,P15924,O75844,P47985 4 +Muscle weakness 0.3005734613557081 0.8046461833953539 0.4210238833296691 1.0 0.8202388059245227 311 Q8TD16,P07602,Q9BZK7,Q10713,Q04446,P56589,P17900,Q04656,O15460,O60313,Q14739,Q9H173,P07384,Q969X5,Q9BUF5,P21359,P49591,Q5KU26,Q93074,P06865,O43909,Q9NQX3,P01889,Q13472,Q70HW3,Q96MW5,P10253,Q8NCH0,Q8N183,Q8NC96,P13473,Q9Y263,Q5XKP0,O94886,Q13510,P40855,P07686,Q7LG56,P00403,O60333,O43505,Q99720,O43772,Q14203,P00374,P41440,Q9BQP7,Q99519,Q9UHX1,Q9NQ11,Q9HC07,P35670,Q96RR1,P54098,P10644,O96000,Q6IA86,P31749,O75489,P51798,Q9GZZ9,O60934,P40763,P46020,P35270,Q13126,P29992,Q6UWE0,Q9H9S5,O95831,Q4J6C6 71 +Amaurosis fugax 0.5306649423627698 0.8043843679329851 0.4211750262899048 1.0 0.8202388059245227 10 P01889,O15460,P60866 3 +Erythroderma 0.5301618180172181 0.8020141278920564 0.4225447859330278 1.0 0.8222157668365296 10 O43909,P48449 2 +Vestibular dysfunction 0.5451292086938067 0.7984902305005447 0.4245860602473961 1.0 0.8241630311381 32 P21359,P41440,Q9BZK7,P06280,Q96RR1,P54098,P10644,O15460,O60333,P01889,P40763,Q9NZ08 12 +Wide intermamillary distance 0.5424288610602579 0.7956928128908869 0.426210605270555 1.0 0.8248495121189764 22 P21359,Q9UBM7,Q9BZK7,P08069,Q96EK5 5 +Venous insufficiency 0.5234937965182305 0.7954227124276704 0.4263676524938051 1.0 0.8248495121189764 7 Q04656,P04062 2 +Abnormal myocardium morphology 0.3069212498714302 0.7948302634873909 0.4267122442043827 1.0 0.8248495121189764 189 Q8TD19,Q04446,P56589,Q7KZN9,P04062,Q96IX5,P16278,Q9NZ08,P21359,P06280,Q9C0B1,P08236,Q14108,Q9Y697,Q13423,P54802,P01889,P15586,Q13472,Q14126,Q07021,P10253,Q8N183,P13473,Q5XKP0,Q9Y4U1,P40855,P00403,Q9H2U2,O43709,Q9BQP7,Q99519,Q96RR1,P54098,P09493,O96000,Q15056,Q9H9S5 38 +Progressive 0.3080803032351685 0.7947700713620864 0.4267472634060141 1.0 0.8248495121189764 113 O60313,P04062,Q9UBS4,P54802,P15586,Q14671,Q8N183,Q5XKP0,Q13510,Q99720,Q9BQP7,Q9UDY2,Q9BV79,Q96RR1,P54098,Q6IA86,P31749,Q9GZZ9,Q13126,O95831 20 +Diminished ability to concentrate 0.5168338559309923 0.7936055709834503 0.4274250882370902 1.0 0.8254769405062006 4 Q96RR1 1 +Abnormal scalp morphology 0.3103746105898825 0.7930025407476909 0.4277763424859258 1.0 0.8258113655733713 122 Q7LGA3,P21359,Q14574,Q9BZK7,P62857,P19022,O00754,P40855,P98164,O95831,O60934,P08069,O96028,Q96EK5,Q15125,P48449 16 +Aplasia involving bones of the lower limbs 0.5139698319364643 0.7909658220172336 0.4289639361853248 1.0 0.8266803591379382 3 Q04656 1 +Thyroiditis 0.5242221833867275 0.7902479009183275 0.4293830064942225 1.0 0.8266803591379382 8 P31749 1 +Abnormal cardiac ventricle morphology 0.3032050954998493 0.788634107441323 0.4303258901895987 1.0 0.8266803591379382 207 Q8TD19,Q69YQ0,P56589,Q7KZN9,Q8N6M0,P98164,P42892,Q14739,P60866,O75787,Q6W2J9,O00192,P08069,P21359,P46783,P62857,P06280,Q9Y4J8,Q9Y4P3,Q93074,Q9C0B1,P47985,Q8NFV4,Q8ND04,Q96MF7,P10253,Q07021,Q8WYQ5,Q7Z392,Q9UBM7,Q8N183,P04114,Q7LG56,P40855,P61313,P00403,P41227,Q7LBC6,O96028,Q9ULC3,Q15427,O43709,O43772,Q9UHX1,Q8WVQ1,O75489,P54098,P19022,Q93063,Q96RR1,Q15056,O75844,Q9H9S5 53 +Abnormality of the sense of smell 0.5386602208226805 0.7883814960640804 0.4304735909915456 1.0 0.8266803591379382 19 Q04656,P04062,Q9NQ11,P31749 4 +Weight loss 0.4571582492154368 0.7881607929186888 0.4306026592646224 1.0 0.8266803591379382 75 Q9BZK7,P07602,P04062,Q04656,O15460,P42892,P60866,Q9NZ08,P38571,P21359,Q13423,P01889,O60333,Q99720,Q14203,P35670,P54098,P10644,P31749,O60934,P40763,O75844,Q99643 23 +Progressive spasticity 0.5374840545335227 0.7872014871718817 0.4311639268022667 1.0 0.8266803591379382 18 P17900,P07602 2 +Nausea 0.541255016445826 0.7868185719024454 0.4313880800563234 1.0 0.8266803591379382 23 P21359,Q9BQP7,P06280,P54098,Q93063,O43464,O60333,Q99643 8 +Mesomelia 0.5196228614802156 0.7864108621831286 0.431626821881125 1.0 0.8266803591379382 6 Q9UBM7 1 +Freckling 0.5299073248948188 0.7861594732853615 0.4317740653691191 1.0 0.8266803591379382 12 P21359,P10644 2 +Abnormality of the calf 0.4714317317604785 0.7857952593025022 0.4319874443835674 1.0 0.8266803591379382 71 Q9NR77,Q8TD19,P34059,Q04656,P16278,Q9H1A4,Q6W2J9,P21359,Q96HY6,Q9Y4P3,P08236,Q7LGA3,Q32P28,Q9NX62,Q9ULC3,Q15427,O43709,Q8WVQ1,Q8NCM8,Q93063,O00754,P51798,Q15056,Q13126,O95831 25 +Abnormality of the carpal bones 0.5388027881844133 0.784883735467229 0.432521738952611 1.0 0.8266803591379382 20 Q93063,O43909,Q04656,Q8WVQ1 4 +Hypoplasia of the corpus callosum 0.3044691676929846 0.7841041285039257 0.4329790131349944 1.0 0.8266803591379382 200 Q8TD16,P07602,Q9UBX3,P04062,Q96N67,Q8N6M0,Q9H9B1,Q96ST3,O75787,P08069,Q96EK5,Q9UQR1,P21359,P49591,P17480,P15311,Q5KU26,Q5JPH6,Q9H490,O43909,O43464,Q9H3S7,Q7LGA3,Q9UBM7,Q15555,P62258,P00403,O43567,Q15125,P48449,P39880,Q9NQ11,Q9UBB6,Q01105,Q96N66,Q9GZZ9,Q9NUM4,Q9H9S5,O95831 39 +Polyneuropathy 0.5385666618037354 0.7837190067587375 0.433205007367172 1.0 0.8266803591379382 20 P21359,P04066,P35670,P07602 4 +Abnormal calcium phosphate regulating hormone level 0.5292065609536268 0.7828392601416488 0.4337215095244771 1.0 0.8266803591379382 12 P21359,O60333,P10644 3 +Abnormality of lipoprotein cholesterol concentration 0.5306327883590112 0.7827854030245934 0.4337531407769255 1.0 0.8266803591379382 13 P38571,Q9Y6B6,P04114 3 +Keratitis 0.5258698039513373 0.7818353449002572 0.4343113462011438 1.0 0.827404154615737 10 Q9NZ08,P01889 2 +Abnormal circulating cholesterol concentration 0.5415523867123818 0.7806983673857304 0.434979921075322 1.0 0.8281993513716631 33 Q9UBM7,Q9Y6B6,Q15904,P04114,P07602,Q15392,P61916,P38571 8 +Abnormality of the gastric mucosa 0.5327719397987718 0.7804412540728853 0.435131193284747 1.0 0.8281993513716631 15 P50851,Q05655,Q9Y4P3,Q6PGP7,P04062,Q15056,Q14739,Q8NFV4,O43709 9 +Abnormal urinary electrolyte concentration 0.5385480079761109 0.7797925149265794 0.4355130128550317 1.0 0.8283321741627491 21 P35670,Q9Y4P3,Q9UNF1,Q9UBS4,Q13423,Q15056,P29992,O43709 8 +Lacrimation abnormality 0.5359942924023341 0.7753075479837533 0.4381579503010093 1.0 0.832542830024342 19 Q9Y4P3,Q15056,Q8NFV4,Q9NX24,O43709,Q07954 6 +Hypopigmented skin patches 0.5405572042477471 0.7751255358178988 0.4382654837372048 1.0 0.832542830024342 27 Q8IZA0,P07602,P53634 3 +Hyperactive patellar reflex 0.5226791384734524 0.7748107835765996 0.4384514762864744 1.0 0.8325550759788624 9 Q9NQ11 1 +Sparse or absent eyelashes 0.5400859619543515 0.7741698772426806 0.438830339159066 1.0 0.8329333944660617 26 P21359,Q14574,O75844,Q15427,Q15125,P48449,Q07954 7 +Hyperreflexia 0.2985901417312489 0.7719213365615177 0.4401610193417433 1.0 0.8347757246166314 239 Q10713,P07602,P56589,Q8TD16,O60313,Q7KZN9,P17900,P04062,Q96IX5,Q9NVC6,O75503,O14773,O75787,Q9NZ08,P07384,Q5KU26,O43395,O43909,Q9NQX3,O43464,P01889,Q8N183,Q15555,O43292,Q5XKP0,P40855,P07686,O43709,Q99720,Q14203,Q99519,Q9NQ11,Q9BV79,O00754,Q96N66,Q15041,Q6IA86,Q15056,Q9NUM4,O14949,P35270,Q9H9S5,O95831 43 +Hepatocellular carcinoma 0.5374933164940722 0.7710811451438225 0.4406588357232581 1.0 0.8353781771254081 22 P35670,P11717 2 +Abnormal vitreous humor morphology 0.5197352094042677 0.7693834697849938 0.4416656987406266 1.0 0.8360188003999219 8 P29992,P04439 2 +Coxa vara 0.532460382840491 0.7677813410071905 0.4426171016639832 1.0 0.8371637935612065 17 Q9Y487,Q04656,Q93063,Q8WVQ1 4 +Vascular tortuosity 0.5107031618496124 0.7655588440709867 0.4439388407475029 1.0 0.8383270790193414 4 P05067 1 +Abnormality of the cerebrospinal fluid 0.310613485949073 0.765248193269196 0.444123766948139 1.0 0.8383270790193414 152 Q10713,P07602,Q7KZN9,P04062,Q15392,P21359,Q9H490,Q9C0B1,Q93074,P08236,O43464,Q8N183,Q9UBM7,Q8TAA9,Q9Y4U1,P40855,P15291,P00403,Q7Z3E5,O96028,O43505,Q15427,Q15125,Q99519,P54098,P10644,O00754,O96000,P31749,P51798,Q9H9S5,O95831 32 +Abnormality of lower lip 0.4753303184091699 0.7645446632412147 0.4445427313368473 1.0 0.8383270790193414 69 Q7LGA3,Q99519,Q69YQ0,Q9BZK7,P04066,P06280,Q93074,P04062,Q96N67,Q9H9B1,Q96ST3,Q15056,P15586,P08069,Q96EK5,O43709,Q96PZ0 17 +Abnormal atrioventricular valve physiology 0.5222170407802473 0.7643258643106146 0.4446730758691526 1.0 0.8383270790193414 50 P21359,Q15904,P04114,P06280,P54098,P09493,P04062,O00754,P19022,P10644,Q15056,O75844,P01889,Q9NZ08,O43709,Q9UQR1 16 +Agenesis of lateral incisor 0.5080916156902457 0.7641881150630251 0.4447551480619376 1.0 0.8383270790193414 3 Q6W2J9 1 +Abnormal jaw morphology 0.2964269317845164 0.7607180738405175 0.4468254771000561 1.0 0.8412219802326271 298 Q8TD19,O15111,Q69YQ0,Q8TD16,P56589,P34059,P04062,Q04656,Q8N6M0,Q15392,P16278,Q9H9B1,Q96ST3,Q14739,P60866,O75787,O00192,P08069,Q96EK5,Q969X5,P21359,P62857,Q9C0B1,Q93074,O43909,Q92917,Q9H3S7,Q13620,Q9NX24,Q8ND04,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q9Y263,P40855,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,P63241,Q96PZ0,Q15125,Q8N3R9,Q9UHX1,O43709,Q9BUR4,Q8WVQ1,Q8NCM8,Q93063,O00754,P10644,P31749,P51798,Q15056,O60934,O75844,Q9H9S5,Q4J6C6 61 +Mitral valve prolapse 0.5365351220826798 0.7561003542879243 0.4495890295781346 1.0 0.8442876807404418 26 P21359,O43909,Q9Y4P3,Q93074,P54098,Q9UBS4,Q15056,Q6W2J9,O43709 9 +Broad nasal tip 0.5093010572570977 0.7554459899972403 0.4499814274528715 1.0 0.8442876807404418 56 Q7LGA3,Q9BZK7,Q9Y487,O43909,Q93074,Q96N67,P10644,Q93063,P16278,P98164,Q7LBC6,P08069,O95831,P10586 14 +Urinary urgency 0.5200902513076632 0.7547860023301711 0.4503773939895357 1.0 0.8444266159992346 10 Q9NQ11 1 +Abnormal greater sciatic notch morphology 0.5126960827778629 0.7545303510401707 0.4505308276864581 1.0 0.8444266159992346 6 O43909,P08236 2 +Widely patent fontanelles and sutures 0.5103930903754427 0.7539025871689047 0.4509077169801858 1.0 0.8447915489442915 5 Q93074 1 +Prolonged neonatal jaundice 0.531178790149991 0.7517697236281548 0.4521895522928321 1.0 0.8458885015447811 19 Q15904,O15118,Q04656,P61916,P11413 5 +Hypercholesterolemia 0.5238303728144785 0.750514098320765 0.4529451359556284 1.0 0.8459442716915049 13 Q15904,P38571 2 +Cranial nerve compression 0.5237672610825268 0.7502156622205467 0.4531248273240305 1.0 0.8459442716915049 13 P21359,O60333,P51798 3 +Emg neuropathic changes 0.5341914256971593 0.7486676369658964 0.4540575543476999 1.0 0.8463939439138185 24 O14773,P07602 2 +Sclerocornea 0.5170562535216331 0.7486465413227437 0.4540702725149357 1.0 0.8463939439138185 9 Q9UBM7 1 +Joint laxity 0.4404963149440119 0.7481659704409167 0.4543600540800847 1.0 0.8463939439138185 78 Q9BZK7,Q15334,P34059,Q04656,P16278,Q96ST3,Q96HY6,Q9Y4P3,Q93074,Q13620,Q8NFV4,Q8NCH0,Q9Y487,Q32P28,O43709,Q9UHX1,Q9HC07,Q8WVQ1,O00754,Q15056 20 +Migraine 0.5338401118108003 0.746906567802088 0.455119961167747 1.0 0.8465600002485553 24 P21359,Q96RR1,O60313,P54098,P05067,P00403,P01889,P60866,Q9NZ08 9 +Abnormal left ventricle morphology 0.5354180343478473 0.7465745950373918 0.4553203883156991 1.0 0.8465600002485553 31 P06280,Q9Y4J8,Q96RR1,P54098,Q9H9S5,P10253,P00403,O75787,Q07021 9 +Back pain 0.533509220944973 0.7452484066693346 0.4561215644767618 1.0 0.8477096971858694 24 P35670,P01889,Q8TAA9,P31749 4 +Intestinal malrotation 0.534704480037721 0.742839825508766 0.4575786606899816 1.0 0.849187546949779 31 P98164,Q93074,Q8NCH0,Q15392 4 +Urinary incontinence 0.5289805758435719 0.7421634742252567 0.4579882958377432 1.0 0.8494388438877015 42 Q9NQ11,P07602,Q93074,P07686,P31749,Q10471,P07384,Q99720 8 +Ovarian cyst 0.5281668478177733 0.7418947978230447 0.4581510779735047 1.0 0.8494388438877015 18 P31751,Q9Y4P3,P10644,P31749,Q15056,O43709,Q99643 7 +Abnormal aortic morphology 0.3052047648020887 0.7415532039463261 0.4583580852479469 1.0 0.8494829901257913 116 Q8TD19,Q69YQ0,P04062,O15460,Q9UBS4,Q9H9B1,P60866,Q6W2J9,O00192,Q9UQR1,P21359,P46783,P62857,Q9Y4P3,Q93074,Q9BXW9,Q9H3S7,P01889,Q8NFV4,Q96MF7,Q8WYQ5,Q7LGA3,Q9UBM7,P55263,P04114,O43709,Q96PZ0,Q8N3R9,Q9UHX1,P19022,P31153,Q15056,O75844 33 +Positional foot deformity 0.3010555348248583 0.740267867687228 0.4591374740680707 1.0 0.8505874819231498 105 Q9NR77,Q8TD19,Q69YQ0,Q8TD16,Q8N6M0,Q15392,Q9H9B1,Q6W2J9,O00192,Q9UQR1,Q969X5,P42356,P08236,Q9H2M9,Q96MW5,Q8NCH0,Q9UBM7,Q8TAA9,Q9Y487,O96028,Q9ULC3,Q15427,Q15125,Q9UHX1,Q8WVQ1,Q8NCM8,O00754 27 +Stillbirth 0.5167376757504699 0.7391648048914152 0.4598069294002846 1.0 0.8508588000414143 10 O75844,Q8TD19,P04062 3 +Abnormality of the thoracic cavity 0.5199364669666212 0.7391195465024027 0.4598344086486488 1.0 0.8508588000414143 12 P01889,P31749 2 +Vertigo 0.533274681705124 0.7378955813867372 0.4605779042653348 1.0 0.8518945919738165 27 P21359,Q9BZK7,P06280,P10644,O15460,P01889,P40763 7 +Abnormality of circulating glucocorticoid level 0.517619015805172 0.7355970645565555 0.4619759495461346 1.0 0.8537334486533742 11 P10644,P31749 2 +Holoprosencephaly 0.5204449876715477 0.7345322470578372 0.4626244140731996 1.0 0.8537334486533742 13 Q9UBM7,O15078,Q92917,Q9H9S5 4 +Short nail 0.5038279603017121 0.7343072138745174 0.4627615222668582 1.0 0.8537334486533742 4 Q9Y487 1 +Recurrent paroxysmal headache 0.5188761385829402 0.7341441668370736 0.4628608777042446 1.0 0.8537334486533742 12 P21359,O60333,P10644,P00403 4 +Broad ribs 0.5071362298690995 0.7291005194657536 0.4659401768881763 1.0 0.8583877102028892 6 Q04656,P16278 2 +Abnormality of subcutaneous fat tissue 0.525384927347947 0.7284447933945206 0.4663413515804291 1.0 0.8583877102028892 18 Q9BZK7,Q9Y487,P31749,Q13472,P08069 5 +Hyperextensible skin 0.5252737514156918 0.7279080717087316 0.4666698617737745 1.0 0.8583877102028892 18 Q04656,P04062,Q8NCH0 3 +Contractures of the joints of the upper limbs 0.4532411292658243 0.7278914204757574 0.4666800555146611 1.0 0.8583877102028892 74 Q7LGA3,Q8IZA0,Q8WVQ1,Q93074,O43909,Q15392,P42892,Q99720 8 +Myopia 0.3003439461621374 0.7247041688568334 0.4686335370591623 1.0 0.8602255067273757 106 Q15555,O43292,Q8WVQ1,Q13555,Q9Y487,O94886,O00754,O15460,P31749,P61586,P98164,Q15056,P51648,Q9H9S5,O43709,Q8NCH0,Q99643 17 +Rickets 0.5100137755239067 0.7244901821792484 0.4687648524340535 1.0 0.8602255067273757 8 Q9UDY2 1 +Scarring alopecia of scalp 0.5016478945171625 0.7244454727477743 0.4687922914600126 1.0 0.8602255067273757 4 Q15125 1 +Abnormal umbilicus morphology 0.4694950867333287 0.7216196687071188 0.470528343130105 1.0 0.8628702775050177 69 Q69YQ0,Q04656,Q9H9B1,P98164,Q14739,Q9C0B1,Q93074,P08236,Q9NQX3,Q8NCH0,Q15555,Q9Y487,Q7LBC6,Q9ULC3,O43709,Q99519,O00754,Q15056,O75844 19 +Capillary malformation 0.5216820074953189 0.7214937821292201 0.4706057648932908 1.0 0.8628702775050177 16 P21359,Q9UHX1,Q8TD19,Q9Y4P3,Q15056,Q8NFV4,O43709 7 +Pectus excavatum 0.3885452801333168 0.7207007048063337 0.4710936786885455 1.0 0.8630385470907433 89 Q7LGA3,P21359,Q15555,Q9H490,Q9Y487,Q93074,O43909,P04062,O00754,Q04656,P31749,Q15056,P08069,O43709,Q8NCH0,Q99643 16 +Multiple rows of eyelashes 0.498229043683579 0.7196175081232241 0.471760529196334 1.0 0.8636216241150418 3 Q9Y606,Q9Y2Z4 2 +Hemangioblastoma 0.5106271523780629 0.7189134432446442 0.4721942529131189 1.0 0.8640744872762954 9 P21359,O60333 2 +Abnormality of reproductive system physiology 0.3072012460770091 0.7161952517810312 0.4738707945685354 1.0 0.8661170179007879 144 Q9BZK7,O60313,P04062,Q8IWS0,Q9H173,O43395,O43464,Q13423,P01889,Q15555,Q13144,P31751,P07686,P00403,O43709,P48449,Q9BQP7,P35670,Q96RR1,P54098,P10644,P31749,Q15056,O60934,P40763,Q9UN37,O75844,Q4J6C6 28 +Myopathy 0.3053812114336178 0.7151039710764115 0.4745448003467172 1.0 0.8670071864490652 104 Q9H173,Q969X5,Q9Y6B6,Q14126,Q07021,Q8NCH0,P13473,P15291,P00403,O43709,Q9BQP7,Q96RR1,P54098,P09493,P10644,O00754,P31749,Q15056,Q13126,Q9H9S5 20 +Macrotia 0.3926866480336969 0.7139876038210158 0.4752348447523165 1.0 0.867925945299918 88 Q7LGA3,Q9BZK7,Q01105,Q9Y4U1,O00754,Q8N6M0,P31749,P16278,Q15056,Q96PZ0,O60934,Q8ND04,Q96EK5,Q8NCH0,P48449 15 +Papilloma 0.5093123297982501 0.7128583363983398 0.4759334227640213 1.0 0.8688595595892782 9 P31749 1 +Abnormal social behavior 0.4681084867689833 0.7114502775246326 0.4768052524387958 1.0 0.8694242845295699 69 P21359,Q5KU26,P07602,Q96RR1,O43909,Q93074,Q96N67,P05067,O43464,Q9NQX3,Q5XKP0,O96000,Q15056,Q10471,O43709,Q8N183,Q15125 17 +Hypoplastic heart 0.5006370197333279 0.7095702774507766 0.4779706566198212 1.0 0.8708226704546601 5 Q9UQR1 1 +Peripheral neuropathy 0.304265103709732 0.7093044874180888 0.4781355443126083 1.0 0.8708226704546601 174 Q10713,P07602,Q04446,Q7KZN9,O15460,Q8IWS0,Q9H173,P07384,P21359,P04066,Q5KU26,P54802,P01889,P51797,Q13472,Q8N183,Q8IV08,P00403,O60333,O00462,P41440,Q9NQ11,P35670,Q96RR1,P54098,P10644,Q15041,P40763,O95831 29 +Hyperlordosis 0.5020298318764663 0.7089810992948495 0.4783362059545752 1.0 0.8708460883436848 56 P21359,P04066,Q8TD16,Q8WVQ1,P34059,Q93074,P16278,Q15056 8 +Low frustration tolerance 0.5078434857987462 0.7061046862406924 0.4801230376576049 1.0 0.8723865695996529 9 P04062 1 +Memory impairment 0.5213087591332017 0.698866451785191 0.4846354950036757 1.0 0.8781769403407755 42 P21359,Q13144,P07602,Q96RR1,P54098,Q9Y4U1,P05067,P31749,P00403,Q9NUM4,P01889,Q9NZ08 12 +Cerebellar atrophy 0.3056907875086992 0.6944436120625551 0.4874040515226541 1.0 0.8811316790645717 143 Q10713,O60313,O75503,O14773,O75787,Q9H173,P17480,Q9H490,Q14108,Q13620,Q13472,Q14671,Q96MW5,O43292,Q8IV08,Q9Y263,Q5XKP0,O43567,Q7Z3E5,P41440,Q9BQP7,Q9NQ11,Q96RR1,P54098,O00754,P51798,Q9GZZ9,Q9UN37,Q9H9S5 29 +Abnormal autonomic nervous system physiology 0.525031497031214 0.6942228811263726 0.4875424453987145 1.0 0.8811316790645717 34 P07602,P06280,Q9H0U9,P07686,P42892 5 +Abnormality of primary teeth 0.5181938854711781 0.6938605150883045 0.4877696876332473 1.0 0.8811316790645717 18 Q9H9B1,P61586,P51798,Q9ULC3,P40763,P53634,O75844 7 +Oral cleft 0.3050555202536209 0.6929092134005531 0.4883665273446076 1.0 0.8811316790645717 165 O15111,Q69YQ0,Q10713,Q15392,Q8IWS0,Q14739,P60866,Q6W2J9,O00192,Q96EK5,P46783,Q5JPH6,P62857,Q9C0B1,Q93074,Q9BXW9,Q8WYQ5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q8TAA9,Q9NX62,P61313,P41227,P15924,Q7Z3E5,O43505,O96028,Q15427,P63241,Q15125,Q9UHX1,Q8NCM8,O15078,O15344,O60934,P40763,O75844,Q9H9S5 40 +Abnormality of the chin 0.421646174061937 0.6926226754444169 0.488546376293943 1.0 0.8811316790645717 81 Q7LGA3,Q9H490,P34059,O43709,Q93074,P19022,P10644,O00754,P16278,Q9H9B1,Q15056,O43567,Q7LBC6,O75844,Q96EK5,Q9UQR1,Q07954 17 +Overlapping toe 0.521539827484051 0.6922963647026795 0.4887512325768832 1.0 0.881158423584373 22 Q9UBM7,Q9UHX1,Q8TD19,P60953,Q93063,Q8N6M0,Q9H2M9,Q15427,Q15125 9 +Abnormality of long bone morphology 0.3008624198549688 0.6899752098271766 0.4902097771121878 1.0 0.8831012962195862 190 Q9NR77,Q8TD19,P56589,P34059,Q04656,Q8N6M0,P16278,Q9H1A4,Q14739,Q9H173,Q6W2J9,P21359,Q9H490,Q96HY6,Q9Y4P3,P08236,Q93074,Q9BXW9,Q9H3S7,O43909,Q8NFV4,Q9H2M9,Q9NX24,Q7LGA3,Q9UBM7,Q9Y487,Q32P28,P40855,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,O43709,Q8N3R9,Q9UHX1,Q9HC07,Q99519,Q8WVQ1,Q9BUR4,Q8NCM8,Q93063,O00754,P10644,P51798,Q15056,Q13126,O75844,O95831 51 +Abnormal peripheral nervous system morphology 0.3031033052911541 0.6895236203846423 0.4904938142422212 1.0 0.8832698317053127 174 Q9BZK7,Q04446,P07602,P56589,O60313,Q04656,P07384,Q9BUF5,Q07954,P21359,Q93074,Q8IV08,Q9Y4U1,Q13510,P40855,P00403,O60333,Q99720,Q14203,P41440,Q9BQP7,Q99519,Q9NQ11,Q96RR1,P54098,Q93063,P10644,P31749,P51798,Q9NUM4,P40763,Q6UWE0,Q9H9S5,O95831,Q99643 35 +Cavernous hemangioma 0.5002296264489549 0.6886060474881303 0.4910712143675346 1.0 0.8839663125086406 7 P31749 1 +Lop ear 0.4886397167305996 0.6877094194655624 0.4916357870789987 1.0 0.884639171395156 2 P78318 1 +Meningioma 0.5018307743246737 0.6870709046922009 0.4920380479591522 1.0 0.8846763972030202 8 P31749 1 +Posterior embryotoxon 0.5165378001093591 0.6808998713559337 0.4959348494996969 1.0 0.8887293243735956 19 Q7LGA3,P56589,Q9Y4P3,P40855,Q15056,Q8NFV4,O00192,O43709,Q8WYQ5 9 +Excessive wrinkled skin 0.5073478718951552 0.6804251258757067 0.4962353161457937 1.0 0.8887293243735956 12 Q9BZK7 1 +Proportionate short stature 0.522086317710187 0.6800316847912655 0.4964843987628773 1.0 0.8887293243735956 35 Q13555,P10619,Q8WVQ1,P10644,P16278,Q15392,Q14739,Q9H173,Q5JRA6 9 +Abnormal response to acth stimulation test 0.4868692829743426 0.6798615587007633 0.4965921241000517 1.0 0.8887293243735956 2 P16435 1 +Anterior pituitary dysgenesis 0.4868692829743388 0.6798615587007475 0.4965921241000617 1.0 0.8887293243735956 2 Q15233 1 +Abnormality of epiphysis morphology 0.4636941849888097 0.6791626030699324 0.4970348396956021 1.0 0.8891763661829221 69 Q7LGA3,Q9UBM7,Q99519,Q8WVQ1,P34059,O43909,P08236,Q04656,P10644,P40855,P16278,P51798,Q9H173,Q5JRA6,O96028,Q15125 16 +Abnormal tongue physiology 0.5179809096445331 0.678861803344194 0.4972254296985803 1.0 0.8891763661829221 21 P10253,Q9NQ11,Q13510 3 +Abnormal circulating androgen level 0.5042000044752702 0.6734110089270301 0.500685846754358 1.0 0.8931155796082378 11 P31749 1 +Patellar dislocation 0.5168404491420419 0.6733306456928069 0.5007369603896712 1.0 0.8931155796082378 21 Q8WVQ1,Q9Y4P3,Q9NX62,Q15056,O00192,O43709,Q15125 7 +Postural instability 0.5146581941993675 0.6718860179298405 0.5016562622914613 1.0 0.8943406721436009 19 Q9NQ11,O75503 2 +Neoplasm of the eye 0.5128940047223709 0.6685538219465375 0.503780137955502 1.0 0.8969465869130625 18 P21359,O60333,P31749,P29992 4 +Atrophy degeneration affecting the central nervous system 0.2952355060408786 0.6683188621336605 0.5039300756090814 1.0 0.8969465869130625 318 Q69YQ0,Q8TD16,P07602,Q9BZK7,Q10713,O60313,O15118,P17900,P05067,P04062,Q8N6M0,O75503,P16278,Q96N67,Q9H9B1,O14773,O75787,Q9NVC6,P49591,P17480,P04066,Q5KU26,Q9H490,P15311,P08236,Q92917,Q9NQX3,O43464,Q9H3S7,P50897,Q8ND04,Q96MW5,Q7LGA3,Q8NC96,P55263,P62258,Q9Y4U1,Q13510,P40855,P00403,Q9NWW5,Q9ULC3,O43709,Q99720,Q96PZ0,Q14203,P00374,P39880,Q9NQ11,Q9UBB6,Q01105,Q96RR1,P54098,O00754,Q96N66,Q9GZZ9,Q15056,Q9NUM4,O60934,Q9UN37,Q9H9S5,O95831 62 +Rapidly progressive 0.5030291211820904 0.6680327717616728 0.5041126735937378 1.0 0.8969465869130625 11 Q14108 1 +Dysphonia 0.5172849190204543 0.6675640987183403 0.504411880897512 1.0 0.8969465869130625 40 P21359,Q9BQP7,Q99519,Q96RR1,Q9Y4P3,Q14203,P54098,Q13510,O94979,O60333,Q15056,Q8NFV4,Q9H173,O43709,Q99643,P42356 16 +Papilledema 0.5156303007403125 0.66746993519986 0.5044720074766589 1.0 0.8969465869130625 21 Q7LGA3,P04062,P31749 3 +Delayed social development 0.4858323494687031 0.6643234682885886 0.5064833037311638 1.0 0.9001774930630152 3 Q9Y2V7,Q9Y3C6 2 +Abnormality of the pharynx 0.4968324985528282 0.6634356429429789 0.5070515845168551 1.0 0.9006728294403354 55 Q13277,P34059,Q93074,P08236,Q13510,P16278,P54802,P01889,P40763,P15586 10 +Horizontal nystagmus 0.516863126554403 0.6625629024183464 0.5076105361250025 1.0 0.9006728294403354 24 O14773,Q9NQ11,P07602 3 +Abnormal diaphysis morphology 0.437601348127899 0.6623018017545713 0.5077778223643321 1.0 0.9006728294403354 76 Q9NR77,Q8TD19,P34059,Q04656,P16278,Q9H1A4,Q14739,Q6W2J9,P21359,Q96HY6,Q9Y4P3,P08236,Q7LGA3,Q9Y487,Q32P28,Q9NX62,Q9ULC3,O43709,Q9HC07,Q8WVQ1,Q8NCM8,Q93063,O00754,P51798,Q15056,Q13126 26 +Aplasia hypoplasia of toe 0.5178865030576876 0.6615582710030882 0.5082543582700876 1.0 0.9006728294403354 37 Q7LGA3,Q9UBM7,Q8N3R9,Q69YQ0,Q9BZK7,P10644,Q13510,Q9H3S7,Q9NX62,Q8IWS0,Q5JRA6,O96028,Q15427,Q96PZ0 14 +Palpitations 0.5143879147996111 0.6614622864938395 0.5083158927421518 1.0 0.9006728294403354 21 P21359,Q96RR1,P54098,P19022,O60333,Q14126,Q99643 7 +Vasculitis 0.5012325405784215 0.6597966062542817 0.5093843614847142 1.0 0.9015580189651028 11 P01889,O15460 2 +Pathologic fracture 0.5071831750443156 0.6591139029028734 0.5098226285459635 1.0 0.9019639559586542 15 P35670,Q14108 2 +Glaucoma 0.3464474675021042 0.6559830336401364 0.5118350407563157 1.0 0.9041267725048115 96 P56589,P60866,Q6W2J9,O00192,P21359,P46783,P62857,O43395,Q9Y4P3,P50213,P61586,Q8NFV4,Q8NCH0,Q9UBM7,Q15555,Q7LG56,P40855,P61313,P41227,O75381,O43505,O43709,Q15125,Q8WVQ1,P31749,Q15056,Q9H9S5 27 +Tall stature 0.4849677350356773 0.6559492703873344 0.5118567651522765 1.0 0.9041267725048115 60 Q9H9B1,P21359,P49591,Q93074,Q9H3S7,Q13423,Q8NCH0,Q7LGA3,Q9UPY3,P62258,O96028,Q96PZ0,Q8N3R9,P54098,P10644,O00754,P31153,P31749,P43034 19 +Abnormal blood phosphate concentration 0.4967954784650705 0.655695545578346 0.5120200354965787 1.0 0.9041267725048115 9 P51798,P10644 2 +Abnormal biliary tract morphology 0.515302275001821 0.6548907147802329 0.5125381188562774 1.0 0.9043528375709888 24 Q10713,P07602,Q5XKP0,P54098,Q14108,P04062 6 +Failure of eruption of permanent teeth 0.4809678371200994 0.6538382784323066 0.5132160022316736 1.0 0.9052044892918488 2 A6NHR9 1 +Abnormal heart valve morphology 0.3997510131756309 0.6510254254679911 0.51503007425558 1.0 0.907041979153338 85 P21359,P06280,P34059,Q93074,P08236,P04062,P10644,Q9UBS4,P16278,O43909,P51798,Q15056,P54098,P01889,O75844,O96028,O43709,Q8NCH0 18 +Abnormal enchondral ossification 0.5160650997990445 0.6470160076015123 0.5176215833676234 1.0 0.9098602282318689 34 Q9UBM7,Q99519,Q8WVQ1,Q96HY6,P56589,O43909,P08236,P10644,P40855,Q14739,O96028,Q15125 12 +Flat face 0.5153416122644557 0.6455803892143306 0.5185511410697623 1.0 0.910061257031258 28 Q15555,Q13555,Q9Y487,P08236,O00754,P40855,Q9H9B1,Q9NX62,Q15125 9 +Abnormality of the tarsal bones 0.5151994475541722 0.6448661793546319 0.5190139104966485 1.0 0.910061257031258 28 Q8WVQ1,Q9Y263,Q04656,Q93063,Q14739,O75787,O75844,Q15125,Q969X5 9 +Hyperhomocystinemia 0.486084096489365 0.644410032426767 0.5193095806441335 1.0 0.910061257031258 5 Q9Y4U1 1 +Profound sensorineural hearing impairment 0.4836138175376314 0.6438730259157024 0.5196577746124955 1.0 0.910061257031258 4 P35241,Q9NR77,P55011 3 +Coronary artery atherosclerosis 0.4834937165568334 0.6433430376001505 0.5200015360603936 1.0 0.910061257031258 4 P04114 1 +Personality changes 0.5075365814691285 0.6431437607884127 0.5201308214758171 1.0 0.910061257031258 18 Q13144,P35670,Q9Y4U1,P04062,P00403,Q9NUM4 6 +Corpus callosum atrophy 0.5050439407086413 0.6428937150198479 0.5202930678604343 1.0 0.910061257031258 16 O75503 1 +Abnormality of the dentition 0.2928142941373164 0.6427925852364051 0.5203586950224788 1.0 0.910061257031258 229 Q69YQ0,Q9BZK7,P34059,Q96N67,P16278,Q9H9B1,Q96ST3,P51648,Q14739,O00192,P21359,P04066,Q93074,P08236,Q9H3S7,Q13620,P61586,Q9NX24,P53634,Q8ND04,Q7LGA3,Q8NC96,Q9UBM7,P23229,Q15555,Q9Y487,O43567,Q5JRA6,O96028,Q9ULC3,O43709,Q15125,Q96PZ0,Q8N3R9,Q9UHX1,Q9HC07,Q01105,P10644,O00754,P31749,P51798,Q15056,Q9GZZ9,P40763,O75844 45 +Coarse hair 0.5074215436356976 0.6426001278621252 0.5204836000963762 1.0 0.910061257031258 18 P54802,Q04656,P15586 3 +Purpura 0.5112168786498953 0.6420564182069243 0.5208365517952793 1.0 0.9103351265264644 22 Q99519,Q9BZK7,P04062,P10644,P40763,Q8NCH0 6 +Congenital malformation of the right heart 0.4934204214954866 0.6404432857855498 0.5218844493094259 1.0 0.9118229809524522 9 P01889,O15460 2 +Underdeveloped supraorbital ridges 0.5028396532071999 0.6388832451685388 0.522898888459538 1.0 0.91290743440771 15 Q9ULC3,Q99519,P40855 3 +Elevated circulating aspartate aminotransferase concentration 0.5023527259428882 0.6366228687756067 0.5243705254573963 1.0 0.9135411094131036 15 Q15904,P38571 2 +Lumbar hyperlordosis 0.5092007338963133 0.6364836046721106 0.5244612638709631 1.0 0.9135411094131036 21 P04066,Q96HY6,O43909,Q93074,Q9H2M9,Q6W2J9,Q9H9S5 7 +Biliary tract abnormality 0.5130426355493231 0.6359226847947186 0.5248268162194112 1.0 0.9135411094131036 27 Q10713,P07602,Q5XKP0,P54098,Q14108,P04062,O96028 7 +Lipodystrophy 0.5128298526100248 0.6344845456622809 0.5257646493811907 1.0 0.9139631079771114 37 Q14126,P04066,P31751,P28070,P09493,Q9UN37,P08069 7 +Profound hearing impairment 0.4837566450088447 0.6341102780072027 0.5260088556512539 1.0 0.9139631079771114 5 Q9NR77,P35241,P55011,P54577 4 +Pes cavus 0.3168207695442531 0.6340392077895456 0.5260552348764833 1.0 0.9139631079771114 101 Q7LGA3,P21359,P07384,Q10713,Q9NQ11,P13473,Q96RR1,O60313,P54098,P04062,Q04656,Q9H3S7,O60333,O95831,Q14739,Q6UWE0,Q99720,Q96PZ0 18 +Subcutaneous nodule 0.5065796770111822 0.6333908867274404 0.5264784147392576 1.0 0.9139631079771114 19 P01889,Q13510,P31749,P06280 4 +Skin pit 0.5016486540299553 0.6333572452476293 0.5265003783519906 1.0 0.9139631079771114 15 Q9ULC3,O96028,Q07954 3 +Fever 0.3887832195060274 0.6327855478581883 0.5268736956618119 1.0 0.9139631079771114 87 Q9NQ11,P07602,P06280,P28070,Q9BZK7,P10644,Q13510,O15460,P01889,P40763,P38571,P10253 12 +Oculomotor apraxia 0.5112847739644859 0.6321679116056833 0.5272771627534012 1.0 0.9139631079771114 25 O43292,P04062,P05067,O14773,Q7Z3E5,P35270 6 +Intestinal atresia 0.4933606976210638 0.6319101257156663 0.5274456064150852 1.0 0.9139631079771114 10 P23229,Q7LBC6 2 +Athetosis 0.5017451474435715 0.6275101726643397 0.5303248700965115 1.0 0.9183130044596192 16 Q96RR1,O14949,O00584 3 +Hyperthyroidism 0.4957848229353023 0.6273190368604773 0.5304501271800646 1.0 0.9183130044596192 12 Q96RR1,P54098,P31749,O00192 4 +Varicose veins 0.4821792786586678 0.6271504868366644 0.530560595579971 1.0 0.9183130044596192 5 P04062 1 +Disproportionate short limb short stature 0.5094456529766112 0.6262423966945984 0.5311559626028244 1.0 0.9186759412865708 24 Q7LGA3,Q9UBM7,Q8WVQ1,Q32P28,P10644,Q15392,Q15125 7 +Long philtrum 0.3008802483084308 0.6235648894686237 0.5329133748374599 1.0 0.921028445442155 139 Q8TD19,Q69YQ0,Q04656,Q8N6M0,P16278,Q96ST3,O00192,P08069,P21359,Q93074,O43909,Q9H3S7,P51797,Q8ND04,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,Q13555,Q9Y263,Q9Y487,O43709,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,P19022,Q93063,Q15056 29 +Postural tremor 0.5043248911445508 0.6227220622148523 0.5334671821151895 1.0 0.9215009702552376 19 Q14108,O14773 2 +Down sloping shoulders 0.5110529083178753 0.622543976168638 0.5335842366045531 1.0 0.9215009702552376 29 Q7LGA3,Q8N3R9,Q9Y4P3,Q04656,Q9H3S7,Q8N6M0,Q13620,P41227,Q15056,Q8NFV4,Q6W2J9,O43709,Q96PZ0 13 +Brachycephaly 0.4430300322144507 0.6221357520880063 0.5338526078941694 1.0 0.9216211998530394 73 P04066,Q9BZK7,Q93074,P04062,Q93063,Q8N6M0,O00754,P10644,Q10471,Q8NCH0 10 +Abnormal corpus callosum morphology 0.2916662103612561 0.6209578392621493 0.5346273636004231 1.0 0.9222719810324262 309 Q69YQ0,Q8TD16,P07602,Q9UBX3,Q10713,O60313,P04062,Q96N67,Q8N6M0,Q15392,O75503,P98164,Q9H9B1,Q96ST3,O75787,P08069,Q96EK5,Q9UQR1,Q9Y3D3,P21359,P49591,P17480,Q5JPH6,Q5KU26,Q9H490,P15311,Q93074,O43909,Q92917,O43464,Q9H3S7,Q7LGA3,Q9UBM7,Q15555,P62258,P00403,O43567,Q7LBC6,Q7Z3E5,O43505,O96028,Q9ULC3,Q15125,Q96PZ0,P48449,P39880,Q9NQ11,Q9UBB6,Q01105,P19022,O00754,Q96N66,Q9GZZ9,Q9NUM4,Q9UN37,Q9H9S5,O95831 57 +Emg abnormality 0.416978004343381 0.6187309191587367 0.5360936376225003 1.0 0.9237704190470212 80 Q9Y6B6,Q9NQ11,P07602,P13473,Q04446,Q96RR1,P09493,Q04656,Q13510,P54098,O14773,P29992,Q14126,Q9H9S5,Q969X5 15 +Abnormality of the hallux 0.4743393366704341 0.6172717314297415 0.5370555092355271 1.0 0.9250840996750148 62 P04062,Q6W2J9,Q93074,Q9Y4P3,Q9H3S7,P61586,Q8NFV4,Q7LGA3,P41227,O96028,Q9ULC3,Q15427,O43709,Q15125,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,P10644,P31749,Q15056 21 +Bruising susceptibility 0.5097615596287154 0.6150248208531284 0.5385383287657448 1.0 0.9260074741928505 35 Q9BZK7,P35670,Q14108,Q04656,P04062,P10644,P51798,P40763,Q8NCH0 9 +Skin vesicle 0.4962176318432694 0.6149734093371877 0.5385722811433602 1.0 0.9260074741928505 14 Q14574 1 +Gastroparesis 0.491329156393897 0.6147667169229698 0.5387087925007545 1.0 0.9260074741928505 11 Q96RR1,P54098,Q04656,O43464 4 +Abnormal lymphocyte morphology 0.5094370778110765 0.6146441203499269 0.5387897704059328 1.0 0.9260074741928505 36 Q99519,P04066,P28070,O43909,O00754,P16278,O60934 7 +Gait ataxia 0.4545269211888496 0.6125906354357746 0.5401470517706617 1.0 0.9279962501150644 69 Q10713,P07602,O15118,O14773,Q9H173,P07384,P17480,Q14108,Q13620,O43292,Q8IV08,Q7LG56,P41440,Q9NQ11,Q96RR1,P54098,O00754,P22570,Q9GZZ9,Q9NUM4 20 +Bone pain 0.5070185456211836 0.6112792506934728 0.5410147251288273 1.0 0.9288757121665424 25 P07602,P35670,Q14108,P04062,P10644,P40763 6 +Abnormality of the lower urinary tract 0.2908872222010734 0.6109615418759795 0.5412250408572632 1.0 0.9288757121665424 233 Q9NR77,Q69YQ0,Q04446,P07602,P56589,Q9UBX3,P51571,P04062,Q04656,Q9H9B1,Q96ST3,O75787,P60866,Q6W2J9,O00192,Q96EK5,P07384,P26358,P46783,P62857,Q9Y4P3,Q93074,Q9BXW9,Q13620,P51797,P01889,Q8NFV4,Q9NX24,Q8ND04,Q8NCH0,P35606,P42695,Q9UBM7,P23229,Q15555,Q8TAA9,P60953,O94886,Q7LG56,P40855,P07686,P61313,P41227,Q7LBC6,O96028,O43709,Q99720,P48449,Q9UHX1,Q9BUR4,Q9NQ11,Q8NCM8,Q96RR1,P54098,Q93063,P10644,P31749,Q15056,Q10471,O60934,O75844 61 +Cellular immunodeficiency 0.4920662847093444 0.6104268471023201 0.5415790883299789 1.0 0.9288757121665424 12 Q9NX24,P31749,Q99643 3 +Axonal degeneration regeneration 0.4783676130729071 0.6104032400748988 0.541594722358036 1.0 0.9288757121665424 5 Q6UWE0 1 +Hypoplasia of penis 0.294002923669894 0.6103038601005031 0.5416605403705694 1.0 0.9288757121665424 111 Q10713,Q9BZK7,Q9H0U9,Q9H9B1,Q8IWS0,Q96ST3,P42892,O43395,Q9Y4P3,Q9BXW9,P50213,Q13620,Q8NFV4,Q9UBM7,Q15555,P62258,O43505,O43709,P48449,Q8NCM8,P19022,Q93063,P43034,Q15056,Q9H9S5 25 +Ankle clonus 0.4919013140899008 0.6096796778644576 0.542074019081765 1.0 0.9291336962385908 12 P07384,P07602 2 +Abnormality of circulating enzyme level 0.2920709402427303 0.6066375754836338 0.5440914579012845 1.0 0.93029206869036 107 Q9H173,Q969X5,Q9Y4P3,Q9Y697,P47985,Q8NFV4,Q14126,Q96MW5,Q07021,P10253,Q7Z392,P13473,Q7LG56,P15291,P15924,Q92734,O43505,O43709,O43772,Q9HC07,Q9BQP7,Q96RR1,P54098,P09493,Q15056,P46020,P50416,Q9H9S5,O95831 29 +Cardiovascular calcification 0.48718837200909 0.604158602762319 0.5457382007585823 1.0 0.9320766250156708 10 P04062,P04114 2 +Deep palmar crease 0.489820499234713 0.6002722219279929 0.5483248282299944 1.0 0.9334002307277842 12 Q9Y487,Q9BZK7 2 +Impaired distal vibration sensation 0.4824113022141419 0.5998812273553128 0.5485853942552166 1.0 0.933501091068418 8 Q96RR1,Q6UWE0 2 +Abnormal ldl cholesterol concentration 0.4895306877085397 0.5989644635509407 0.5491965822623832 1.0 0.933872721398692 12 P38571,Q9Y6B6 2 +Paraganglioma 0.4859413695154102 0.598584754283371 0.5494498251357198 1.0 0.93394385599499 10 P21359,O60333 2 +Cranial hyperostosis 0.4890924375029624 0.5969880550436437 0.5505153556488189 1.0 0.9354121305033248 12 O00754,P31749 2 +Cough 0.5033644285633686 0.5905947228986516 0.5547920015432879 1.0 0.9412991259261712 26 Q9NR77,P41440,Q9BZK7,P04062,O15460,P10644,P15924,P01889,P40763,Q6W2J9 10 +Abnormal corneal epithelium morphology 0.4919437393727188 0.5886935205176298 0.5560668852603081 1.0 0.941397781451638 15 Q9NZ08,P51648,P01889,O75844,Q96EK5 5 +Abnormal eyelash morphology 0.4172320894762024 0.5886669073033111 0.5560847413448626 1.0 0.941397781451638 79 P21359,Q14574,Q8WVQ1,Q5KU26,Q8N6M0,P48449,Q07954 7 +Pulmonary artery stenosis 0.4933000220787137 0.5884704448286842 0.5562165661157401 1.0 0.941397781451638 16 P27635,Q9Y4P3,P51798,P41227,Q15056,Q8NFV4,Q6W2J9,O43709 8 +Abnormality of hand joint mobility 0.4777457806434476 0.5882989452515112 0.5563316534390119 1.0 0.941397781451638 7 O43567 1 +Abnormality of central nervous system electrophysiology 0.2993494059963744 0.5880137267330922 0.5565230792502978 1.0 0.941397781451638 155 P07602,P56589,Q9UBX3,O60313,Q96N67,Q9NVC6,O75503,Q8IWS0,P21359,P49591,P17480,P15311,Q14108,Q9H3S7,Q13620,P51797,P50897,Q8NC96,O43292,P62258,Q9Y263,P40855,P00403,O43567,O96028,Q15125,P48449,Q99519,Q9UBB6,Q96N66,Q9GZZ9,Q9NUM4,Q9H9S5 33 +Mutism 0.4902691497030496 0.587831762479993 0.5566452222303164 1.0 0.941397781451638 14 Q9NUM4,Q13510 2 +Decreased circulating cortisol level 0.4795967494102968 0.5874591574755077 0.5568953730312103 1.0 0.941397781451638 8 P31749 1 +Supernumerary tooth 0.4785070082081918 0.5826656277128575 0.5601184163991939 1.0 0.944473419551994 8 Q9UBM7,Q9UHX1 2 +Contractures involving the joints of the feet 0.4988212811139395 0.5826551199960462 0.5601254914315255 1.0 0.944473419551994 22 Q8IZA0,Q8TD16,O60313,Q8IWS0,P15924,Q6W2J9,Q9H9S5,P63241 8 +Death in adulthood 0.493054444157018 0.5812268448575821 0.5610875773278157 1.0 0.9455296198650128 17 Q9Y4P3,P54098,P05067,Q15056,Q8NFV4,Q9UN37,O43709 7 +Reduced vital capacity 0.4641487164355349 0.5809507393999341 0.5612736541179593 1.0 0.9455296198650128 2 P55072 1 +Abnormal periventricular white matter morphology 0.500696383073561 0.5805500062942851 0.5615437747862912 1.0 0.9455296198650128 41 P17900,P07602,O75503 3 +Abnormality of neuronal migration 0.2987719126768564 0.5788864789208437 0.5626657741298828 1.0 0.9457733010545232 153 Q10713,Q8TD16,P56589,Q9BZK7,Q15392,Q96EK5,P49591,P15311,Q5KU26,Q9C0B1,Q93074,Q9NQX3,Q9UBM7,P62258,Q9Y487,P40855,P23258,Q7Z3E5,O43505,Q15427,P39880,Q9UBB6,Q01105,P19022,Q96N66,P31749,O60934,Q9UN37,Q9H9S5 29 +Abnormal proximal phalanx morphology of the hand 0.4708926451722262 0.5778677275982368 0.5633534252005876 1.0 0.9457733010545232 5 Q9ULC3 1 +Rhizomelia 0.486458996625024 0.5777137112138698 0.5634574205912628 1.0 0.9457733010545232 13 Q9UBM7,Q15392 2 +Skin nodule 0.4985753953860438 0.5774259495024663 0.5636517486853629 1.0 0.9457733010545232 23 P04114,P06280,Q13510,P31749,P01889 5 +Spastic tetraparesis 0.4997433252292779 0.5759613998402434 0.5646412725344367 1.0 0.9465804702610928 25 P07602 1 +Abnormal sclera morphology 0.5017818028684987 0.5747968854472456 0.5654286734015304 1.0 0.9475579178037212 30 Q8WVQ1,P10644,P31749,Q9UN37,Q8NCH0 5 +Abnormality of the shoulder girdle musculature 0.5016362722880683 0.5727567697611303 0.566809393429101 1.0 0.9484952020963316 35 Q8TD16,P07602,Q9Y487,O60313,Q96RR1,P54098,Q9H9S5 7 +Abnormal cardiac ventricular function 0.4974974062632846 0.572290622636414 0.5671251015922372 1.0 0.9484952020963316 23 P04114,Q96RR1,P54098,Q7LG56,Q9H9S5,P00403,Q13472,O75844,P10253 9 +Abnormality of the humeroradial joint 0.476048743139 0.5718860356344752 0.5673991851220088 1.0 0.9484952020963316 8 P10644 1 +Thin eyebrow 0.4903976141311759 0.5690171013420554 0.5693445344307744 1.0 0.9489124815893516 17 P21359,P48449,Q96EK5,P62857 4 +Abnormal eyelid morphology 0.2803127087958109 0.5690070955451532 0.5693513246680004 1.0 0.9489124815893516 361 O15111,Q69YQ0,Q9BZK7,Q10713,P56589,P04062,Q04656,Q8N6M0,Q15392,Q96N67,P98164,Q9H9B1,Q8IWS0,Q96ST3,P60866,P08069,O00192,Q96EK5,Q9UQR1,Q07954,P21359,Q14574,Q5KU26,P62857,Q9H490,Q93074,Q92917,Q9H3S7,Q13620,P61586,P01889,Q9NX24,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,P23229,Q15555,P04114,Q13555,P62258,Q8NC96,Q9Y487,P40855,O96028,Q9ULC3,Q15427,Q15125,P48449,Q96PZ0,O43709,P63241,Q8N3R9,Q9UHX1,Q8WVQ1,Q9UBB6,Q9BUR4,Q8NCM8,P19022,Q93063,O00754,P10644,P31749,P43034,Q9GZZ9,Q15056,Q10471,O60934,O75844,Q4J6C6 70 +Hepatosplenomegaly 0.4985653538042978 0.5689968647488118 0.5693582676366427 1.0 0.9489124815893516 41 Q99519,P10619,P04062,Q13510,O00754,P16278,P07686,P38571 8 +Abnormality of circulating leptin level 0.46626885909335 0.5683833352803336 0.569774703607433 1.0 0.9489124815893516 4 P31751 1 +Hyposmia 0.4859557408357609 0.5683167838363578 0.5698198844425164 1.0 0.9489124815893516 14 Q9NQ11,O15078,P04062,O43464,P26196 5 +Abnormal thyroid hormone level 0.4603127766302769 0.5646227230944709 0.5723304061809444 1.0 0.9506893264094596 2 O14654 1 +Poor motor coordination 0.4873984761489436 0.5615051284637139 0.5744532351772116 1.0 0.9523657442442524 16 P35670,Q9Y4U1,Q9H9S5,O75503 4 +Abnormality of the synovia 0.3765992269106992 0.5611004806013905 0.5747290405474439 1.0 0.9523657442442524 88 Q9UBM7,Q8WVQ1,Q8TD16,P62258,Q9Y487,O43909,P08236,Q93063,Q04656,Q9NQX3,P16278,P31749,Q9ULC3,O75844,Q9H173,O96028,Q15427,Q969X5 18 +Skin tags 0.4964208658628448 0.5599685381847398 0.5755008977262923 1.0 0.9527303330085032 25 Q9UHX1,Q93074,Q93063,O96028,P31749,Q6W2J9,Q96MF7,Q15427 8 +Septo optic dysplasia 0.4591324874594432 0.5596227391599418 0.5757367913174705 1.0 0.9527806928405104 2 Q8WWQ0 1 +Periventricular heterotopia 0.4768299327281337 0.558217001321795 0.57669621279544 1.0 0.9530093393986426 10 Q9UBM7 1 +Hand clenching 0.4748430495093775 0.5579147927733432 0.5769025696985097 1.0 0.9530093393986426 9 Q8TD16,Q6W2J9 2 +Bicornuate uterus 0.474416618718101 0.5560514423846554 0.5781756884532516 1.0 0.9532976643641174 9 Q9UBM7,P98164,Q15427 3 +Kinetic tremor 0.4976204250481909 0.5558944334425572 0.5782830238469421 1.0 0.9532976643641174 38 P31749,Q14108,P07602,Q9Y287 4 +Gowers sign 0.4846420239030927 0.5555533907766786 0.5785162017512673 1.0 0.9532976643641174 15 Q13510 1 +Alternating esotropia 0.4622882592810726 0.5513840866323502 0.5813704071140517 1.0 0.9564168074870332 4 P51797 1 +Abnormal erythrocyte morphology 0.2912928459473639 0.5512820131572584 0.5814403666823262 1.0 0.9564168074870332 202 Q9BZK7,P07602,Q9UBX3,Q7KZN9,O60313,P04062,P38571,P02786,Q9Y6B6,P62857,P06280,P28070,Q14108,P01889,Q8NB49,Q15904,P11413,Q8N183,P04114,Q9Y4U1,Q13510,P00403,O60333,Q6P4A7,P00374,P41440,P35670,P54098,Q93063,P10644,P51798,Q10471,P40763,O60934,Q99643 35 +Abnormal qrs complex 0.4570669814104514 0.5509007058409086 0.5817017435895133 1.0 0.9565074414980757 2 P14923 1 +Bifid tongue 0.4639942580862958 0.5482299665977703 0.5835340082381981 1.0 0.9588724903271334 5 Q9UBM7 1 +Embryonal renal neoplasm 0.4758665576773018 0.545871323204121 0.58515439182216 1.0 0.96082185371082 11 Q93063 1 +Platyspondyly 0.4956607712122702 0.5439590971127445 0.5864696201756161 1.0 0.9612298596427812 37 P04066,Q8WVQ1,P34059,O43909,P08236,Q04656,Q32P28,O00754,P16278,Q14739,Q5JRA6,O95831 12 +Aplasia hypoplasia involving bones of the feet 0.4358259228485193 0.5436030373409437 0.5867146692108114 1.0 0.9612298596427812 72 Q69YQ0,Q9BZK7,Q8IWS0,Q9H173,P08069,Q9H3S7,Q13620,Q7LGA3,Q9UBM7,Q13555,Q13510,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,P10644,Q10471 22 +Congenital blindness 0.4577158632936079 0.542685527915326 0.5873463401670977 1.0 0.9612298596427812 3 Q96MF7 1 +Craniosynostosis 0.4919999495604026 0.5408850391367654 0.588586823485888 1.0 0.9612298596427812 43 Q69YQ0,O43909,Q93074,O00754,P31749,Q9NX62,P51798,P40763,Q9ULC3,Q8NCH0 10 +Atelectasis 0.472773604976876 0.54046060450158 0.58887942249588 1.0 0.9612298596427812 10 Q13510 1 +Generalized neonatal hypotonia 0.4686750969873495 0.5398453808073022 0.5893036678446577 1.0 0.9612298596427812 8 Q93074 1 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.4595633341007139 0.539824005086143 0.5893184106273226 1.0 0.9612298596427812 4 Q96RR1 1 +Cochlear malformation 0.4544113307760417 0.5397400773026756 0.5893762970597589 1.0 0.9612298596427812 2 Q9Y619 1 +Abnormal cochlea morphology 0.4544113307760417 0.5397400773026756 0.5893762970597589 1.0 0.9612298596427812 2 Q9Y619 1 +Joint contracture of the hand 0.4844338439675958 0.5393639950226704 0.5896357196598485 1.0 0.9612298596427812 50 P42892,Q8WVQ1,Q15392,Q8IZA0 4 +Perisylvian polymicrogyria 0.4594446196930744 0.5393218323110502 0.5896648068965771 1.0 0.9612298596427812 4 P42356 1 +Delayed epiphyseal ossification 0.4592001993998952 0.5382882991388366 0.5903780281188193 1.0 0.9612298596427812 4 Q96HY6 1 +Aplasia hypoplasia affecting the anterior segment of the eye 0.4946161122942005 0.537946075018813 0.5906142778514174 1.0 0.9612298596427812 31 P21359,Q7LGA3,Q9Y297,Q9Y4P3,Q9BXW9,P98164,O60333,Q15056,P08069,O96028,O43709,Q99643 12 +Abnormal mitral valve physiology 0.4926790223662196 0.5372874896242212 0.5910690456361465 1.0 0.9612298596427812 41 P21359,P04114,P06280,P54098,P09493,P04062,O00754,Q15056,O75844,P01889,Q9NZ08,O43709,Q9UQR1 13 +Autoimmune hemolytic anemia 0.4719417879003874 0.5368366366563503 0.5913804623976575 1.0 0.9612298596427812 10 P50851,Q969U7,O60934,P40763 4 +Abnormal reflex 0.2778056560145495 0.5367971265900355 0.5914077566992619 1.0 0.9612298596427812 374 Q8TD16,P07602,Q10713,Q7KZN9,Q9H0U9,Q04446,P17900,P04062,Q96IX5,Q04656,O75503,P56589,O60313,Q9NVC6,O14773,O75787,Q9H173,Q9NZ08,P07384,Q969X5,Q9Y6B6,Q5KU26,O43395,Q93074,O43909,Q9NQX3,O43464,P54802,P01889,P10253,Q8N183,Q15555,O43292,P04114,Q8TAA9,Q5XKP0,Q13510,P40855,P07686,O60333,O43505,O43709,Q99720,Q14203,P41440,Q9BQP7,Q99519,Q9NQ11,Q9BV79,Q96RR1,P54098,O00754,Q15041,Q96N66,Q6IA86,Q9GZZ9,Q15056,Q9NUM4,O14949,P35270,Q6UWE0,Q9H9S5,O95831 63 +Macrovesicular hepatic steatosis 0.4678043502135784 0.5360919741342061 0.5918949866957417 1.0 0.9612298596427812 8 P54098,Q5JPH6,Q5XKP0 3 +Ulnar bowing 0.4535261138979211 0.5360335006305386 0.5919353976438455 1.0 0.9612298596427812 2 P16435 1 +Subglottic stenosis 0.4535261138979037 0.5360335006304653 0.5919353976438961 1.0 0.9612298596427812 2 Q7Z2Z2 1 +Absent frontal sinuses 0.4535261138979035 0.5360335006304643 0.5919353976438968 1.0 0.9612298596427812 2 P46100 1 +Abnormality of frontal sinus 0.4535261138979035 0.5360335006304643 0.5919353976438968 1.0 0.9612298596427812 2 P46100 1 +Abnormal choroid morphology 0.4943547272459827 0.5351847024862684 0.5925221433238441 1.0 0.9613454088847674 33 P21359,Q10713,P56589,Q5XKP0,P40855,P31749,P41227,O75381,Q6W2J9,O43505,Q9H9S5,P04439 12 +Spastic diplegia 0.4911233326433985 0.5346577621835075 0.592886533622166 1.0 0.9616001596383296 25 Q6IA86,Q99720,P07602 3 +Short lingual frenulum 0.4582461547724289 0.5342591230182058 0.5931622692094112 1.0 0.961661145977214 4 O75844 1 +Hypoplasia of the musculature 0.4606496079859877 0.5340037887263464 0.5933389127972415 1.0 0.961661145977214 5 Q9Y487 1 +Bladder neoplasm 0.4707366583657241 0.5315969367880178 0.5950051868125319 1.0 0.9640248257336514 10 P31749 1 +Acne 0.478505115586633 0.5280384852576561 0.5974726247777142 1.0 0.9670089218479097 15 P01889,Q92542 2 +Sparse hair 0.4058398287767841 0.5262618203265561 0.5987063063946527 1.0 0.9677427462227312 80 P21359,Q14574,Q8WVQ1,P08069,Q9Y487,Q93074,Q93063,Q04656,P53634,Q96EK5,Q15125,P48449 12 +Dark urine 0.4511655355562088 0.5261833467214617 0.5987608235740816 1.0 0.9677427462227312 2 P36551 1 +Delirium 0.4536207137459735 0.5254916633248486 0.599241447172296 1.0 0.9681820872954484 3 Q9Y4U1 1 +Absent septum pellucidum 0.4920859204016751 0.523793147270471 0.6004224201949828 1.0 0.9684030478066558 33 P49591,Q9UBB6,O96028,Q9H9B1,Q15392,Q96N66,O43505,Q9H9S5 8 +Airway obstruction 0.4753944506457325 0.5211769622653328 0.6022435011853275 1.0 0.969535529172252 14 O00192,O75844,P06280 3 +Sparse eyebrow 0.4913938594800091 0.5208324190810534 0.6024835170768901 1.0 0.969535529172252 36 P21359,Q14574,P62857,Q96EK5,P48449,Q07954 6 +Arachnoid hemangiomatosis 0.4681472546017844 0.5203821226993046 0.6027972677601041 1.0 0.969535529172252 10 P21359,O60333 2 +Increased blood pressure 0.4124692499219189 0.5200441830105111 0.6030327805509901 1.0 0.9695780178276496 78 Q10713,Q04446,P04062,Q9UBS4,P42892,O00192,P38571,P21359,P06280,P01889,P04114,Q8TAA9,P00403,O60333,O43709,Q9UDY2,Q93063,P10644,Q15056,O75844,Q99643 21 +Skeletal dysplasia 0.4834358164965518 0.5195299657189079 0.6033912219770081 1.0 0.969794627370372 48 P21359,Q9HC07,Q99519,Q8WVQ1,P10619,Q96HY6,P56589,Q8NCM8,O43909,P40855,P16278,P31749,P51648,Q14739,Q15427,O95831 16 +Hypotension 0.487769334377911 0.518759381716932 0.6039285462135033 1.0 0.969794627370372 25 P07602,Q04656,P04062,P07686,Q13423,P29992,Q14203 7 +Abnormal circulating creatinine concentration 0.4593461068511375 0.5183512589975074 0.6042132151117112 1.0 0.969794627370372 6 Q10471 1 +Abnormal saccadic eye movements 0.48828781762647 0.5179168048394859 0.6045163165829721 1.0 0.9699453840813984 26 Q8IV08,O14773,Q9NQ11 3 +Abnormal delivery 0.485252677563399 0.5146371851167385 0.6068065753923204 1.0 0.9722743918777434 23 Q9UBM7,Q9Y487,O60313,O75718,Q9NQX3,Q9H3S7,Q8NC56,Q7LBC6,O75844,Q969X5 10 +Abnormality of the pulmonary vasculature 0.4883792002492316 0.5143243898398684 0.6070252122814086 1.0 0.9722887424348504 41 Q7LGA3,Q8N3R9,P60953,O75718,Q9Y4P3,Q9H3S7,Q15392,P51798,P41227,Q15056,Q8NFV4,Q6W2J9,Q8ND04,O43709,Q8WYQ5,Q96PZ0 16 +Hypertensive crisis 0.455667854104996 0.5129982694039931 0.6079525312614926 1.0 0.972691291175853 5 P01889 1 +Metaphyseal striations 0.4556487445410384 0.5129181309144208 0.6080085901011485 1.0 0.972691291175853 5 Q13126 1 +Bone marrow hypercellularity 0.4682343872086976 0.5125902739908877 0.6082379580579889 1.0 0.972691291175853 11 P10644,P40763 2 +Abnormal sacrum morphology 0.4893102321116118 0.5124653413377557 0.6083253708022371 1.0 0.972691291175853 38 P04066,Q8TAA9,P62258,O43909,Q93074,Q8N6M0,O96028,Q15056,P01889,Q9ULC3,O43709,Q15125 12 +Low set posteriorly rotated ears 0.41490044555887 0.5111025885758851 0.6092792234473623 1.0 0.9734468597940178 77 Q10713,P56589,P04062,Q15392,Q6W2J9,P21359,Q9Y4P3,Q8NFV4,Q9H2M9,Q8NCH0,Q9UBM7,Q15555,P60953,Q9Y263,P40855,P41227,O75381,O96028,Q15427,O43709,Q8WVQ1,Q15056,Q10471,Q4J6C6 24 +Aplasia hypoplasia involving the femoral head and neck 0.4639305165921488 0.5107224105446245 0.6095454459667491 1.0 0.9734468597940178 9 Q8WVQ1,O95831 2 +Muscle stiffness 0.4834295831673322 0.510565034814431 0.6096556646335984 1.0 0.9734468597940178 22 Q9NQ11,P07602,Q15392 3 +Camptodactyly of toe 0.4596443810623017 0.5102910696397135 0.6098475582707832 1.0 0.9734468597940178 7 Q8IWS0,P15924,Q6W2J9 3 +Agitation 0.4889023780889493 0.5097368280552675 0.6102358481564145 1.0 0.9737314617691996 31 P04062,P05067,P10644,P42892,P48449 5 +Weakness due to upper motor neuron dysfunction 0.2939729882274198 0.5091890371122828 0.610619726666106 1.0 0.974008831286802 147 Q04446,P07602,P56589,O60313,Q9UBX3,P17900,P04062,Q7KZN9,O75787,Q9NZ08,P07384,P21359,Q5JPH6,Q13423,P01889,Q8N183,Q5XKP0,Q13510,P00403,Q9NQ11,P54098,O00754,Q15041,P31749,Q9H9S5,O95831 26 +Abnormal platelet granules 0.4464443788728211 0.5066359542028148 0.6124102760788408 1.0 0.9765290406387842 2 O00203 1 +Abnormality of the diaphragm 0.4876600309095265 0.5051788065684236 0.6134332543971257 1.0 0.9771706556560568 30 Q9UBM7,P62857,P98164,Q7LBC6,O96028 5 +Abnormal epiphysis morphology of the phalanges of the hand 0.4625726970397473 0.5049251913762225 0.6136113798353899 1.0 0.9771706556560568 9 Q5JRA6,P10644 2 +Aortic arch aneurysm 0.4621120755964089 0.5029625048373149 0.6149906342093416 1.0 0.978042314847444 9 Q9Y4P3,O43709,Q15056 3 +Polymicrogyria 0.4027584857068625 0.5009659632947541 0.6163950774187033 1.0 0.9788438267090848 80 Q10713,Q8TD16,P56589,Q15392,Q96EK5,P49591,P15311,Q9NQX3,Q9Y487,P40855,Q7Z3E5,O43505,Q15427,P39880,Q9UBB6,Q01105,Q96N66,Q9UN37,Q9H9S5 19 +Abnormal morphology of the olfactory bulb 0.4474616292797916 0.4999204264703203 0.6171311087280158 1.0 0.979069786229975 3 Q8N3U4,A6NHR9 2 +Single naris 0.4474616292797916 0.4999204264703203 0.6171311087280158 1.0 0.979069786229975 3 Q8N3U4,A6NHR9 2 +Erythrocyte inclusion bodies 0.4500208834557754 0.4998640647459748 0.6171707968838078 1.0 0.979069786229975 4 Q9Y606,P11413 2 +External genital hypoplasia 0.2916519167089636 0.4993291607340979 0.6175475151352621 1.0 0.9793323624084166 131 Q10713,Q9BZK7,Q9H0U9,Q9H9B1,Q8IWS0,Q96ST3,P42892,Q9H173,O43395,Q9Y4P3,Q93074,Q9BXW9,P50213,Q13620,Q8NFV4,Q9UBM7,Q15555,P62258,O43505,Q9ULC3,O43709,P48449,Q8NCM8,P19022,Q93063,P43034,Q15056,O75844,Q9H9S5 29 +Absent eyebrow 0.4545687344404887 0.4982657469696935 0.6182967471538781 1.0 0.97973408328583 6 P15924,O75844,Q9H1A4 3 +Arthrogryposis multiplex congenita 0.4861666542593705 0.4962073472214675 0.6197481278132115 1.0 0.9809297593012548 38 P23229,Q8TD19,Q8TD16,P04062,Q15392,Q8NCH0,P40763,O75844,Q969X5 9 +Wide anterior fontanel 0.4848685711903636 0.4959711594223329 0.6199147591186034 1.0 0.9809297593012548 28 O15111,Q9Y487,Q93074,Q32P28,P40855,P98164,Q15125 7 +Neurogenic bladder 0.4622188172351486 0.4949374974165692 0.6206442407874853 1.0 0.9812230973513704 10 P51797,Q8TAA9,Q9NQ11,Q04446 4 +Proptosis 0.475164415129888 0.4933812299628768 0.6217432423850942 1.0 0.98195061922459 51 P21359,Q9UBM7,Q8WVQ1,Q5KU26,O43909,O00754,P31749,Q9NX62,P98164 9 +Abnormal blistering of the skin 0.479441111268685 0.4922283699381318 0.6225579110072561 1.0 0.98195061922459 22 P23229,Q14574,Q9BUR4,Q9H1A4,P51798,P01889,Q9NX24,Q9NZ08 8 +Abnormal circulating lipid concentration 0.3939502783542229 0.4911904977245117 0.6232917190538763 1.0 0.98195061922459 82 Q9UBM7,Q9Y6B6,P04114,P31751,P07602,P06280,P38571,P28070,Q9Y4U1,P40855,Q15392,P61916,Q15056,Q10471,Q15904 15 +Oromotor apraxia 0.4475937407735527 0.4898368528369941 0.6242493504178952 1.0 0.98195061922459 4 Q8N3U4,P39656,P42356 3 +Abnormality of the elbow 0.4477048743579858 0.4885504740007516 0.6251599832895138 1.0 0.9823337317904016 65 P21359,Q7LGA3,Q8WVQ1,P34059,Q93074,Q04656,Q13510,P10644,Q9H173 9 +Recurrent pharyngitis 0.4467227913760482 0.4862528468771456 0.6267879066577116 1.0 0.9844422867296706 4 P01889 1 +Broad foot 0.4577413013448967 0.4844403937476274 0.6280733570022625 1.0 0.9855756874516044 9 O95831,Q9BZK7 2 +Hallux valgus 0.4752249023653729 0.4830736001695757 0.6290434781840588 1.0 0.9865628132763022 20 Q9Y4P3,P04062,P31749,Q15056,Q15427,O43709 6 +Decreased specific anti polysaccharide antibody level 0.4457968941185168 0.4824510318025622 0.629485576528886 1.0 0.9865628132763022 4 Q9Y2V7,Q05655 2 +Abnormal prostate morphology 0.4562171508555928 0.4780256662813736 0.6326319372626228 1.0 0.9897146737809656 9 O60934 1 +Metaphyseal cupping 0.4415588345442675 0.475757279595227 0.63424730819712 1.0 0.9915498974393866 3 O95831 1 +Action tremor 0.4546292887422001 0.4736935024839335 0.6357184874095065 1.0 0.9923113871424634 61 Q9NQ11,P07602,Q14108,O14773,Q9Y287,Q99720 6 +Hyperactivity 0.2920133263439459 0.4721278647387173 0.6368355243119468 1.0 0.9927546110513688 158 Q10713,O75503,Q96ST3,P60866,O00192,P21359,P49591,P17480,P15311,Q93074,Q9H3S7,Q13620,P54802,P15586,Q7LGA3,Q8NC96,Q9UBM7,Q7LBC6,O43709,Q15125,Q96PZ0,Q8N3R9,O00462,Q9UBB6,P19022,P10644,Q96N66,Q9GZZ9,Q15056,O60934,P35270 31 +Abnormal lactate dehydrogenase level 0.4714472563845281 0.471695409123049 0.6371442144681634 1.0 0.9927546110513688 19 O43505,P10253,Q9H173 3 +Limb girdle muscle weakness 0.4797429797740712 0.4691134966285571 0.6389885123582228 1.0 0.9937295834232516 29 Q8TD16,P07602,Q96RR1,O60313,P54098,Q13126,Q9H9S5 7 +Atrophy degeneration involving the spinal cord 0.4558080979481753 0.4678060627716673 0.6399232846078751 1.0 0.993987497812142 10 Q96RR1,Q9Y4U1 2 +Skin dimple 0.4798731148397088 0.4675882425750742 0.6400790745022764 1.0 0.993987497812142 30 Q8TAA9,P62258,Q93074,O43909,Q9Y4P3,P43034,Q8N6M0,O96028,Q15125,Q15056,Q9ULC3,O43709,Q969X5 13 +Reduced tendon reflexes 0.2888841582758668 0.4667256258810454 0.640696193123161 1.0 0.9941341190232476 183 Q10713,Q04446,P07602,P56589,Q8TD16,Q9H0U9,P04062,Q04656,O75787,Q9H173,Q969X5,Q9Y6B6,O43909,P54802,P10253,P04114,Q8TAA9,Q13510,P40855,O60333,O43505,Q99720,P41440,Q9BQP7,Q96RR1,P54098,Q15041,Q9GZZ9,Q6UWE0,Q9H9S5,O95831 31 +Pyoderma gangrenosum 0.4364119209206228 0.4658167429753251 0.6413466795818712 1.0 0.9941341190232476 2 P61011 1 +Radioulnar synostosis 0.4725084891466484 0.4656586686862891 0.6414598413020394 1.0 0.9941341190232476 21 Q8WVQ1,Q9Y4P3,Q15056,Q6W2J9,O96028,Q15427,O43709 7 +Ectropion 0.4570046913138557 0.4646135233559068 0.642208246129417 1.0 0.9943528607791186 11 P04062 1 +Pleural effusion 0.4530061193379811 0.464588522719612 0.642226152971308 1.0 0.9943528607791186 9 Q9NZ08,P01889 2 +Gingival overgrowth 0.4797408788694755 0.4617160911115537 0.6442849302836011 1.0 0.9968465871621816 35 Q9UBM7,Q99519,Q9BZK7,P08236,P10644,O00754,P16278,Q15056,P40763 9 +Bradykinesia 0.476139606542855 0.4608600129883418 0.6448990420412177 1.0 0.9971402616874202 26 Q5JPH6,Q9NQ11,Q96RR1,P04062,O43464,Q96IX5,O75787,P35270,Q14203 9 +Abnormality of the fontanelles or cranial sutures 0.2849466335254246 0.4608519617237877 0.6449048188053856 1.0 0.9971402616874202 116 O15111,Q69YQ0,P56589,Q04656,P98164,Q93074,O43909,Q8NCH0,Q9Y487,Q32P28,P40855,Q9NX62,Q9ULC3,Q15125,O00754,P31749,P51798,P40763,O75844,O95831 20 +Abnormal fingertip morphology 0.4782041223421557 0.4596126159958278 0.6457943019855963 1.0 0.9980713155298004 30 P50851,Q7LGA3,Q8N3R9,P62266,P46821,Q9BZK7,Q93074,Q7Z6Z7,Q9H3S7,P41227,P15924,P26196,Q9H2M9,Q6W2J9,O75844,Q96PZ0 16 +Aniridia 0.459378269752701 0.4590432447387866 0.6462031118861125 1.0 0.9980713155298004 13 P21359,O60333,Q99643 3 +Abnormality of the hypothenar eminence 0.4399173309713684 0.4585140292893553 0.6465831856483379 1.0 0.9980713155298004 4 P62913,Q7Z392,Q96IJ6 3 +Central adrenal insufficiency 0.4399173309713553 0.4585140292893021 0.6465831856483761 1.0 0.9980713155298004 4 Q9NSE4,Q9NW13,P35222 3 +Prominent digit pad 0.472865490746915 0.4577229558932315 0.6471514934081393 1.0 0.99828392379692 23 Q7LGA3,Q8N3R9,Q9BZK7,Q93074,Q9H3S7,P41227,Q6W2J9,Q96PZ0 8 +Abnormal chorioretinal morphology 0.4774458823241888 0.4559990777350948 0.6483906414132945 1.0 0.998764242038426 30 Q10713,P56589,Q5XKP0,P40855,P31749,P41227,O75381,Q6W2J9,O43505,Q9H9S5,P04439 11 +Spondyloepimetaphyseal dysplasia 0.4443220404613594 0.4559418440893101 0.6484317984969707 1.0 0.998764242038426 6 O95831 1 +Hemianopia 0.4443087743036353 0.455887752187694 0.6484706973193626 1.0 0.998764242038426 6 P31749 1 +Abnormal cortical gyration 0.2887743187675435 0.4553631149869308 0.6488480266446262 1.0 0.998907137965183 132 Q10713,Q8TD16,P56589,Q9BZK7,Q15392,Q96EK5,P49591,P15311,Q5KU26,Q9C0B1,Q9NQX3,P62258,Q9Y487,P40855,P23258,Q7Z3E5,O43505,Q15427,P39880,Q9UBB6,Q01105,Q96N66,Q9UN37,Q9H9S5 24 +Focal dystonia 0.4731955734902071 0.4549183402848714 0.6491679879175305 1.0 0.998941829546831 24 Q9NQ11,Q99720 2 +Decreased circulating igg level 0.457295982714205 0.4502118824122655 0.6525576692152646 1.0 1.0 13 Q15904 1 +Upper limb postural tremor 0.4351995690635477 0.4501267332372048 0.6526190616836718 1.0 1.0 3 Q9NR77 1 +Vascular dilatation 0.4168841617079775 0.4499331369856804 0.6527586531400262 1.0 1.0 74 P21359,Q7LGA3,Q93074,Q04656,P10644,Q93063,Q15056,P01889,P40763,P10253,Q96PZ0 11 +Decreased facial expression 0.4768661349780163 0.4498320928759467 0.652831515240127 1.0 1.0 32 Q9NQ11,Q9Y263,Q96RR1,P54098,Q04656,P04062,Q9GZZ9,O75787,P35270,Q9H9S5,Q969X5,Q14203 12 +Abnormal liver physiology 0.4426577791182026 0.4491707074299357 0.6533085167584383 1.0 1.0 6 Q13510 1 +Hyperlipidemia 0.4765846982895064 0.4484758403884691 0.6538098183934007 1.0 1.0 32 P28070,P38571,P04114,P06280 4 +Incoordination 0.4313285455380796 0.4479800043262381 0.6541676275837192 1.0 1.0 69 P07602,Q01105,P35670,P54098,Q96RR1,P04062,Q9NQX3,Q13510,O00754,O75503,O14773,O75787,Q9H9S5 13 +Non midline cleft lip 0.4443241699353863 0.4466371612562839 0.6551370596898578 1.0 1.0 7 O15111,O60934 2 +Abnormal leukocyte count 0.2814235114622018 0.4458559295563039 0.6557013181527678 1.0 1.0 110 Q9BZK7,P62857,P38571,P28070,O43909,Q9Y4U1,Q14108,P04062,P10644,O43464,O75787,O60934,P40763,Q15904,P02786 15 +Abnormality of toe 0.287384535629886 0.4458490436774576 0.6557062924753552 1.0 1.0 187 Q9NR77,Q8TD19,Q69YQ0,Q10713,Q9BZK7,P04062,Q8N6M0,Q8IWS0,Q96ST3,Q14739,Q6W2J9,O00192,P08069,Q9Y4P3,Q93074,O43909,Q9BXW9,Q9H3S7,Q13620,P61586,Q8NFV4,Q9H2M9,Q96MW5,Q7LGA3,Q9UBM7,P60953,Q9Y263,Q13510,Q9NX62,P41227,O60333,Q7Z3E5,Q5JRA6,O96028,Q9ULC3,Q15427,P63241,Q99720,Q96PZ0,Q8N3R9,Q9UHX1,Q15125,O43709,Q8WVQ1,Q8NCM8,Q93063,P10644,P31749,P11233,Q15056,O75844,Q10471,Q6UWE0 53 +Congenital malformation of the great arteries 0.28138142118096 0.4452946200538485 0.6561068552786793 1.0 1.0 110 Q8TD19,O15111,Q69YQ0,P51571,O15460,Q15392,Q9H9B1,P42892,Q6W2J9,O00192,Q9Y3D3,Q9UQR1,Q9C0B1,Q9Y4J8,Q9Y4P3,Q9BXW9,P01889,Q8NFV4,Q8WYQ5,Q9UBM7,P40855,Q9ULC3,Q15427,O43709,Q9UHX1,Q93063,P31153,Q15056,O75844 29 +Dyspnea 0.2902489458601353 0.4448759595917588 0.6564093967678324 1.0 1.0 103 Q9BZK7,P07602,P04062,Q969X5,P62857,P06280,P01889,P10253,P04114,Q9Y4U1,Q13510,O43567,Q14203,Q9BQP7,Q96RR1,P54098,P10644,P40763,O95831 19 +Facial diplegia 0.4560098538700028 0.4447804509169207 0.6564784232106426 1.0 1.0 13 Q96RR1,P54098,Q7LG56,Q9H9S5 4 +Vertebral compression fracture 0.4585688878085865 0.4410842351003106 0.6591520160579694 1.0 1.0 15 Q14108 1 +Neuroendocrine neoplasm 0.4551237877920372 0.4410490105948619 0.6591775161173885 1.0 1.0 13 P21359,O60333,P10644 3 +Elevated hepatic transaminase 0.2842998317609966 0.440268498379078 0.6597426535521937 1.0 1.0 104 Q10713,Q14739,O75787,P38571,Q9Y3D3,Q9Y6B6,P28070,Q9Y697,P22695,P01889,Q15904,Q96MW5,P10253,Q07021,P55263,Q5XKP0,Q7LG56,Q13510,P40855,O43772,P35670,Q96RR1,P54098 23 +Peripheral pulmonary artery stenosis 0.4511194767523168 0.4399851357022408 0.659947873117835 1.0 1.0 11 Q9Y4P3,Q15056,Q8NFV4,Q6W2J9,O43709 5 +Weakness of muscles of respiration 0.4750081841666269 0.4382760073472487 0.6611862161558024 1.0 1.0 36 Q9BQP7,Q8TD16,Q13510,O95831,P10253,Q969X5 6 +Aplasia hypoplasia of the skin 0.4563768820497552 0.4368152167033897 0.6622453625764604 1.0 1.0 57 P23229,P10644,Q15392,Q13126,P53634,O96028,Q15125,Q8NCH0,Q07954 9 +Pulmonary fibrosis 0.4648036761041284 0.4367486304592091 0.6622936570645153 1.0 1.0 20 Q8IZA0 1 +Bone spicule pigmentation of the retina 0.4436890334022949 0.4350043182567675 0.6635592930090928 1.0 1.0 8 Q15555,Q8WWY3,P20839,O75643,P50213,Q96S66,P36405 7 +Accelerated skeletal maturation 0.4476843977068095 0.4340392355767213 0.6642599495457844 1.0 1.0 10 Q8WVQ1 1 +Abnormal visual electrophysiology 0.4656954395787294 0.4324403350122874 0.6654214079388612 1.0 1.0 50 O14773,P07602,O75503 3 +Natal tooth 0.4426254602844089 0.4306852780827226 0.6666972247501666 1.0 1.0 8 P15924,O75844,Q69YQ0,Q9H9B1 4 +Hypoglycemic seizures 0.4400628944188001 0.4293716341112328 0.6676527933582113 1.0 1.0 7 P31751 1 +Abnormality of the spinal cord 0.3902477041984408 0.4290519591294175 0.6678854123899567 1.0 1.0 81 Q8TD19,Q10713,P34059,P05067,P16278,Q96ST3,O00192,P21359,O43909,Q8TAA9,Q9Y4U1,Q7LG56,O60333,O96028,Q9ULC3,O43709,Q9UHX1,Q96RR1,P54098,Q93063,O00754,P31749,Q15056,Q9H9S5 24 +Decreased mean corpuscular volume 0.4269696075538514 0.4283677027560312 0.6683834348787119 1.0 1.0 2 Q8NBF2 1 +Hypochromia 0.4269696075538469 0.4283677027560129 0.6683834348787252 1.0 1.0 2 P11172 1 +Cerebellar vermis atrophy 0.448158572588991 0.4277377524260521 0.6688420608681276 1.0 1.0 11 Q14671,Q10713,Q13620 3 +Abnormal adipose tissue morphology 0.4430951205939398 0.4276120159013228 0.6689336162803987 1.0 1.0 63 Q14126,P04066,Q9BZK7,P31751,P28070,Q8TAA9,P09493,P31749,Q13472,Q9UN37,P08069 11 +Short digit 0.2891271641971472 0.4261991803213993 0.6699627147214788 1.0 1.0 158 Q69YQ0,Q9BZK7,Q04656,Q9H9B1,Q8IWS0,Q96ST3,Q14739,P60866,Q9H173,Q9Y3D3,P62857,Q9C0B1,Q93074,O43909,Q9H3S7,Q13620,Q7LGA3,Q9UBM7,Q13555,Q13510,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q96PZ0,P48449,Q8WVQ1,P10644,P31749,P51798,O75844,O95831,Q99643 34 +Abnormal circulating aromatic amino acid concentration 0.4341689028068588 0.425157196445755 0.6707220849158015 1.0 1.0 5 P61457 1 +Chorioretinal hypopigmentation 0.4257893183830081 0.4237571511582226 0.6717429304291114 1.0 1.0 2 Q9Y619 1 +Cessation of head growth 0.436273270725214 0.4234787682682967 0.6719459860680201 1.0 1.0 6 Q9Y263,Q13144,Q9NR50 3 +Abnormal protein glycosylation 0.4573575719941152 0.4224868408875782 0.6726697036867266 1.0 1.0 17 Q9Y487,P51571,Q9Y2V7,Q9H9E3,O75787,Q10471,Q15904,Q96MW5 8 +Esophageal stricture 0.4332640405474957 0.4215697065009622 0.6733391217003111 1.0 1.0 5 P01889 1 +Heterogeneous 0.4665461071951763 0.4203401142232008 0.6742370093862684 1.0 1.0 47 Q15555,P54098,Q14203,P05067,P31749,P51798,P61916,O60333,P01889,Q14126,O75844,P11717,P53634 13 +Abnormality of the antitragus 0.4273907910271437 0.4192618030393502 0.6750248088443032 1.0 1.0 3 Q92643,Q9H2M9 2 +Abnormal cortical bone morphology 0.4591470107827633 0.4178344620825427 0.6760681524382082 1.0 1.0 19 P21359,O00754,P40855,P31749 4 +Slurred speech 0.4436322246730515 0.4174692168086951 0.6763352359063519 1.0 1.0 10 Q9Y487,Q99519,P16278 3 +Gastritis 0.4321878191861683 0.417315248260361 0.6764478367106457 1.0 1.0 5 P50851,Q6PGP7 2 +Lipoatrophy 0.4601116089155068 0.4162790050047735 0.6772058537660706 1.0 1.0 20 Q14126,P04066 2 +Abnormality of the achilles tendon 0.4508301013476103 0.41564370883346 0.6776707378115345 1.0 1.0 14 Q9H9S5,Q15041,Q8TD16 3 +Hypertrichosis 0.2821118358335122 0.4123878084035074 0.6800551976702613 1.0 1.0 104 Q99519,Q9H490,P08069,Q7KZN9,P19022,Q96N67,O00754,P16278,Q9H9B1,P54802,P15586,P53634,Q96EK5,Q8N183 14 +Abnormality of prenatal development or birth 0.2790852647004647 0.4121012945420034 0.6802651798726518 1.0 1.0 258 Q8TD19,O15111,Q8TD16,Q04446,P56589,Q7KZN9,O60313,O15118,P04062,Q9UNF1,P16278,Q96ST3,Q14739,P60866,O00192,Q969X5,P62857,Q93074,P08236,O43909,Q92917,Q9H3S7,Q9NQX3,Q70HW3,Q07021,Q8N183,Q7LGA3,Q8NC96,Q9UBM7,P23229,Q8TAA9,P10619,P62258,Q9Y487,Q9Y4U1,Q13510,P40855,P61916,O43567,Q7LBC6,O96028,Q15427,O43709,P63241,O43772,Q15125,Q9UHX1,Q99519,Q8NCM8,O75489,Q93063,P43034,P31153,O96000,P51798,Q15056,Q9NUM4,Q9GZZ9,O75844,Q4J6C6 60 +Cone shaped epiphyses of the phalanges of the hand 0.4379741234794966 0.4119491431871248 0.6803766996596758 1.0 1.0 8 P10644 1 +Drowsiness 0.4329203737193493 0.4101733129414526 0.6816788160446339 1.0 1.0 6 O00754 1 +Increased body weight 0.2766599794358568 0.4078305579491385 0.6833980773918746 1.0 1.0 106 Q10713,Q9H9B1,Q8IWS0,Q96ST3,O75787,P08069,O00192,Q9C0B1,O43395,Q93074,Q15555,P31751,Q5JRA6,Q9ULC3,O43709,Q8WVQ1,P35670,P10644,P31749,Q15056 20 +Abnormality of limb epiphysis morphology 0.4682953848433496 0.4074822481440356 0.6836538296156629 1.0 1.0 33 Q7LGA3,Q8WVQ1,O43909,Q04656,P10644,Q9H173,Q5JRA6,O96028,O95831 9 +Abnormality of the brainstem white matter 0.4260803666833561 0.4036768071010221 0.6864503968089786 1.0 1.0 4 Q10713 1 +Lens luxation 0.4232585596221905 0.4032158058163904 0.6867894730590174 1.0 1.0 3 O96007,Q99622 2 +Unilateral renal agenesis 0.4556778873206881 0.402953202217893 0.686982651775268 1.0 1.0 19 Q7LGA3,Q9UBM7,Q9UHX1,P10644,Q15427,P35606,P42695 7 +Genu varum 0.4476668377927342 0.4025317505423094 0.6872927264058162 1.0 1.0 14 Q9ULC3,Q8WVQ1,Q96HY6 3 +Underdeveloped nasal alae 0.4581024038263565 0.4021259326856325 0.6875913484845684 1.0 1.0 21 Q5KU26 1 +Pharyngitis 0.4281266607609677 0.4013846733232691 0.6881369318116255 1.0 1.0 5 P01889 1 +Limited elbow extension 0.4432725306712667 0.3997455268497535 0.6893439560423082 1.0 1.0 12 Q93074,Q04656 2 +Retrognathia 0.3829468657627847 0.399592621252711 0.6894565920760891 1.0 1.0 82 Q7LGA3,Q4J6C6,Q8WVQ1,Q9C0B1,P04062,Q8N6M0,Q15392,O60934,Q5JRA6,P08069,O75844,Q15427,Q15125,Q8NCH0,Q96PZ0 15 +Stomach cancer 0.4390249278241794 0.3988623639690935 0.6899946220373081 1.0 1.0 10 P10644 1 +Anencephaly 0.4494486606445323 0.3957858463409742 0.6922630190269676 1.0 1.0 16 Q92917,Q15427,Q8TAA9,O43505 4 +Abnormality of the tragus 0.421192443919702 0.3952705153184229 0.6926432568182421 1.0 1.0 3 Q5SRE5,A6NHR9 2 +Aplasia hypoplasia of the tragus 0.421192443919702 0.3952705153184229 0.6926432568182421 1.0 1.0 3 Q5SRE5,A6NHR9 2 +Adult onset 0.4094530381473774 0.3952332534280086 0.6926707535656307 1.0 1.0 74 P41440,Q8IV08,P31751,P07602,Q04446,Q9NQ11,P54098,O15118,P04062,Q96RR1,P31749,Q9NWW5,Q13472,Q07021,Q99643,Q14203 16 +Ventriculomegaly 0.2838048387074317 0.3949391965303236 0.6928877618131644 1.0 1.0 194 Q69YQ0,Q10713,P07602,Q8TD16,Q9BZK7,P04062,Q8N6M0,Q15392,P16278,Q9H9B1,Q96ST3,O75787,O00584,Q96EK5,Q9Y3D3,Q9UQR1,P17480,Q5KU26,Q9C0B1,Q93074,O43909,O43464,Q9H3S7,Q13620,Q96MW5,Q8NCH0,Q9UBM7,P62258,Q9Y263,Q9Y487,P15291,Q7Z3E5,O43505,O96028,Q15125,P39880,Q9UHX1,Q8NCM8,Q01105,Q9H9S5 40 +Broad neck 0.4458007412184759 0.3948529932034614 0.6929513829627574 1.0 1.0 14 P21359,Q93074,P62857 3 +Increased fecal porphyrin 0.4181174387724959 0.3941929030556314 0.6934386249371594 1.0 1.0 2 P36551 1 +Abnormal stool composition 0.4181174387724959 0.3941929030556314 0.6934386249371594 1.0 1.0 2 P36551 1 +Abnormality of finger 0.2775613015780575 0.393644938074318 0.6938431986536822 1.0 1.0 288 Q8TD19,O15111,Q69YQ0,Q10713,Q8TD16,Q15334,Q9BZK7,Q04656,Q8N6M0,Q9H9B1,Q9H1A4,Q8IWS0,Q96ST3,P42892,Q14739,P60866,Q9H173,Q6W2J9,O00192,P08069,Q96EK5,P42356,P46783,P62857,P28070,Q9Y4P3,Q93074,O43909,Q9BXW9,Q9H3S7,Q13620,Q92917,Q8NFV4,Q9H2M9,Q14671,P53634,Q96MW5,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P60953,P62258,Q9Y263,Q13510,P61313,P41227,O43567,Q7Z3E5,Q5JRA6,O96028,Q15427,O43709,Q15125,Q96PZ0,Q9ULC3,Q8N3R9,Q9UHX1,Q8WVQ1,Q9NQ11,Q8NCM8,Q93063,P43034,P31153,P31749,P10644,P51798,Q15056,O75844,O95831 70 +Abnormal anatomic location of the heart 0.4435769320365498 0.3932416404817689 0.6941410172497644 1.0 1.0 13 Q8TD19,Q7Z3E5,Q10713,P19022,Q6W2J9,O75844 6 +Abnormal renal insterstitial morphology 0.4433316159060413 0.3922431580674215 0.6948785583802128 1.0 1.0 13 Q9Y4P3,O43709,Q15056,Q04446 4 +Brushfield spots 0.425503101125688 0.3911998253765109 0.6956495373715066 1.0 1.0 5 P40855,P56589 2 +Abnormality of periauricular region 0.4612554398217313 0.3894709351614795 0.6969278071087679 1.0 1.0 27 Q93063,O96028,Q9ULC3,Q15427,Q07954 5 +Nephropathy 0.4571404575260642 0.3878569757538521 0.6981218788995442 1.0 1.0 23 Q10713,P62258,P06280,Q8NCM8,Q9Y4U1,Q14108,P00403 7 +Symptomatic seizures 0.4314734535948133 0.3861954317457949 0.6993519367531946 1.0 1.0 8 P31751 1 +Large intestinal polyposis 0.4399124480977012 0.3861565892446312 0.6993807017060025 1.0 1.0 12 Q9UPY3,P31749 2 +Hydrops fetalis 0.4576596203874396 0.3823045523700638 0.7022354783915556 1.0 1.0 49 Q8TD19,Q99519,P10619,Q04446,P62857,P08236,P04062,Q9Y4U1,Q13510,P16278,O96000,Q14739 12 +Abnormality of the zygomatic bone 0.384439208764596 0.3819596766118771 0.7024912744288581 1.0 1.0 81 Q9BZK7,Q9H9B1,P98164,Q14739,O00192,P21359,Q9H490,Q9Y4P3,Q93074,P61586,Q8NFV4,Q9H2M9,Q9Y487,Q9ULC3,Q15427,O43709,Q15125,Q9HC07,Q8WVQ1,P10644,O00754,Q15056,O60934,O95831 24 +Infantile muscular hypotonia 0.4216792124525867 0.381664852370387 0.7027099737292701 1.0 1.0 69 Q99519,P07602,P17900,Q13510,O00754,P16278,P10253 7 +Gynecomastia 0.4504381725665748 0.380753809325176 0.7033859368284119 1.0 1.0 19 Q8IWS0,P31751,P31749,Q99643 4 +Tongue fasciculations 0.4401743342935321 0.379459355031097 0.7043467813151931 1.0 1.0 13 Q9H0U9,Q13510 2 +Receptive language delay 0.4453124517316926 0.3786787897395978 0.704926405730913 1.0 1.0 16 Q7LGA3,Q96PZ0,Q9H3S7,Q9H9B1 4 +Megalencephaly 0.4167650531286886 0.3784248497065775 0.7051150109520783 1.0 1.0 3 P52788,O00459 2 +Abnormal csf protein level 0.4413153685816488 0.3765724871566367 0.7064913371595511 1.0 1.0 14 P00403,P54098,Q7LG56,P07602 4 +Progressive hearing impairment 0.4372950411135629 0.3756689479904275 0.7071630256516195 1.0 1.0 12 P35237,Q96RR1,O60313,P33993,P00403,Q15031 6 +Abnormal lumbar spine morphology 0.4371952820094015 0.3752709498909448 0.7074589686996504 1.0 1.0 12 P08236,P04062,O00754 3 +Erythroid hyperplasia 0.4183643342190801 0.3740907196134388 0.708336822953838 1.0 1.0 4 Q9Y606,O75533,Q86SX6 3 +Acute hepatic failure 0.4424616372628693 0.3739888918911431 0.7084125805066919 1.0 1.0 15 P35670,P38571 2 +Abnormality of the breast 0.2790619209291822 0.3738038939175428 0.7085502222520321 1.0 1.0 104 Q7LGA3,Q9UBM7,P21359,Q15555,P31751,Q9BZK7,Q99643,P19022,P10644,P31749,Q8IWS0,O60934,P08069,O96028,Q96EK5,P10586 16 +Broad forehead 0.4610786318052592 0.373215555115744 0.7089880199177763 1.0 1.0 41 P21359,Q9H490,P19022,O00754,P98164,Q15056,O43709,Q8NCH0 8 +Abnormally large globe 0.4302814033431839 0.3727754827162282 0.7093155516915657 1.0 1.0 9 P31749 1 +Prominent forehead 0.3865792345488916 0.3707220454281726 0.7108445686820573 1.0 1.0 80 Q7LGA3,P04066,Q93074,Q93063,O00754,Q15392,P15586,Q96PZ0 8 +Osteolysis 0.4563726265260307 0.3677133335419602 0.713086997367012 1.0 1.0 27 P21359,Q14108,P04062,O00754,P53634 5 +Abnormality of the plantar skin of foot 0.457446702891693 0.3677131041675523 0.7130871684173314 1.0 1.0 46 P07858,Q9BZK7,P09493,P31749,Q14126,P53634 6 +Retinopathy 0.4588439575729737 0.3669999706150845 0.7136190399231386 1.0 1.0 31 Q9Y6B6,Q99519,O96028,P51648,P01889,P40763,Q5JRA6,Q9NZ08 8 +Cerebral white matter atrophy 0.4490148545072202 0.3633201477037615 0.7163657444880791 1.0 1.0 21 O75503 1 +Pancreatic cysts 0.4181840154658315 0.3632471007546679 0.7164203057162659 1.0 1.0 5 Q9UBS4 1 +Neoplasm of the stomach 0.4487940036749248 0.3623903019998547 0.7170603855966036 1.0 1.0 21 P10644,P31749,Q99643 3 +Widely spaced teeth 0.4566453648230791 0.3623287764124542 0.7171063565419014 1.0 1.0 29 P08236,O00754,P16278,P34059 4 +Abnormal odontoid tissue morphology 0.45734858385687 0.3607954770855472 0.7182523441590225 1.0 1.0 44 P21359,Q9UBM7,P23229,Q9HC07,P34059,Q9Y4P3,P16278,Q9H1A4,P61586,P31749,P51648,Q15056,Q5JRA6,O00192,O43709 15 +Subcutaneous hemorrhage 0.4571515635560881 0.3597898931494603 0.7190042618646151 1.0 1.0 44 Q99519,Q9BZK7,P35670,Q14108,Q04656,P04062,P10644,P51798,P40763,Q8NCH0 10 +Abnormality of the kidney 0.2706127992281604 0.3590400000066682 0.7195651658799036 1.0 1.0 363 Q8TD19,Q13277,O15111,Q9BZK7,Q99643,Q10713,P56589,Q04446,Q69YQ0,P04062,Q04656,O15460,Q15392,Q9H9B1,P98164,Q9UNF1,Q9UBS4,P60866,Q9NZ08,Q9UQR1,P21359,P62857,P06280,O43909,Q92917,Q14108,Q9Y697,P01889,Q07021,Q8NCH0,Q8N183,Q7LGA3,Q9UBM7,P23229,P04114,Q8TAA9,P62258,Q9UPY3,Q9Y4U1,P40855,P00403,O60333,Q5JRA6,O43505,O96028,Q9ULC3,Q15125,Q15427,O43709,Q9BQP7,Q99519,P35670,Q93063,P10644,O96000,P31749,Q15056,O60934,P40763,P29992,Q9H9S5,Q4J6C6 62 +Abnormality of the gallbladder 0.4584067019863742 0.3586832862614388 0.7198320331527417 1.0 1.0 40 Q9UBM7,Q69YQ0,P04066,P07602,P04062,P40855,Q15056,Q9UN37,O96028,O43709 10 +Reticular hyperpigmentation 0.4083800531130191 0.3577349152088208 0.72054170137353 1.0 1.0 2 P09884 1 +Intracranial hemorrhage 0.4539910004920006 0.357214738696785 0.7209310529425146 1.0 1.0 27 P21359,Q9Y4U1,Q04656,P05067,P04062,P31749,O60333,O75844 8 +Carcinoma 0.4164205552274084 0.3566169555464732 0.7213785823437713 1.0 1.0 5 P43246,O60832,Q07864,P28340 4 +Abnormality of the midface 0.2847225137570762 0.3564406039981306 0.7215106258812258 1.0 1.0 160 Q8TD19,Q69YQ0,Q8TD16,Q9BZK7,Q04656,Q9H9B1,P98164,Q14739,Q07954,P21359,Q9H490,P62857,Q93074,O43909,Q9Y487,O43567,O96028,Q9ULC3,Q15427,Q15125,Q8WVQ1,Q93063,O00754,P10644,O60934,O95831 26 +Abnormality of the thyroid gland 0.2751059587716425 0.3562735539321804 0.7216357125723696 1.0 1.0 111 O60313,Q04656,P42892,P60866,O00192,P04066,Q13423,Q07021,Q9UPY3,Q9Y263,P00403,O43709,Q96RR1,P54098,Q93063,P10644,P31749,Q15056,P40763,Q99643 20 +Abnormal patella morphology 0.4546122632177768 0.3532503488181075 0.7239007648924687 1.0 1.0 29 Q8WVQ1,Q9Y4P3,Q9NX62,Q9H1A4,Q15056,O00192,Q9ULC3,O43709,Q15125 9 +Aganglionic megacolon 0.447804487480856 0.3528885493126512 0.7241719956142925 1.0 1.0 22 Q9UBM7,Q7Z3E5,Q10713,Q04656,Q9BXW9,P42892,P41227,Q15427,Q6W2J9,O00192,Q96EK5 11 +Scrotal hypoplasia 0.4461477707115973 0.3512996195032201 0.725363580367858 1.0 1.0 21 Q8IWS0,Q9H0U9,Q93074,Q9UBM7 4 +Wide nasal bridge 0.2833987502093863 0.3496514362581356 0.726600303959613 1.0 1.0 172 Q69YQ0,P56589,Q8N6M0,Q96ST3,P60866,O00192,P08069,Q96EK5,P46783,Q5KU26,P62857,O43395,Q9Y4P3,Q93074,Q9H3S7,P50213,P61586,Q8NFV4,Q9H2M9,Q14671,Q7LGA3,Q9UBM7,Q15555,P60953,Q9Y487,P40855,Q9NX62,P61313,P41227,O75381,O96028,O43709,Q96PZ0,Q8N3R9,Q9UHX1,Q99519,Q01105,O15344,P10644,O43172,P11233,Q15056,P40763 43 +Prominent ear helix 0.4117145110216181 0.3492122256466882 0.7269299885427853 1.0 1.0 4 Q96N67 1 +Abnormal echocardiogram 0.417071805548733 0.3491648419327442 0.7269655591946909 1.0 1.0 6 Q96RR1,P54098 2 +Truncal obesity 0.4392428266449143 0.3472319225443793 0.7284170903237039 1.0 1.0 17 Q8IWS0,P08069,P10644,P31751 4 +Osteoporosis 0.4237262644904666 0.3464671344387938 0.7289916794012132 1.0 1.0 66 P34059,Q04656,P16278,Q9H1A4,P21359,Q9Y4P3,Q9NX24,O43292,Q7LG56,Q13510,O96028,O43709,Q9HC07,Q9BUR4,Q8WVQ1,P35670,P54098,Q96RR1,P10644,Q15056 20 +Excessive daytime somnolence 0.4333336786998944 0.3446856899349307 0.7303306773794604 1.0 1.0 14 Q9UBM7,Q96RR1,P31749,Q9H9S5,P26358 5 +Exaggerated cupid s bow 0.4153618906942418 0.3427799982277994 0.7317639744346733 1.0 1.0 6 Q96KP1,P11233,P61978,Q969N2,Q6DKJ4 5 +Cardiac arrest 0.4550825574549392 0.3421415472569842 0.7322443719059382 1.0 1.0 36 P04114,Q9Y4J8,Q9H0U9,Q9Y4P3,P04062,O15460,P31749,P14923,Q15056,P15924,P01889,Q8NFV4,Q9H2M9,Q14126,P50416,O43709,O43772 17 +Abnormality of the ribs 0.4207224929190766 0.3421348025919986 0.7322494474372014 1.0 1.0 67 Q8TD19,P34059,Q04656,P16278,Q14739,Q96HY6,P54802,P15586,Q9UBM7,Q8TAA9,Q32P28,O96028,Q15427,Q9UHX1,Q93063,O00754,P51798,O75844,O95831 19 +Tinnitus 0.4356029223823185 0.3393918391383997 0.7343145655829062 1.0 1.0 16 P21359,P31749,O60333,O95831,Q99643 5 +Arachnodactyly 0.4533125794783073 0.3377013336735674 0.7355882696225327 1.0 1.0 33 Q93074,Q8N6M0,P31153,Q96ST3,O00192,O96028,Q8NCH0,P53634 8 +Peripheral hypomyelination 0.4027736795514893 0.3373205387688677 0.7358752783854996 1.0 1.0 2 O60231 1 +Abnormal palate morphology 0.2759809836320955 0.3371343603450087 0.7360156162666416 1.0 1.0 295 Q8TD19,O15111,Q69YQ0,Q10713,Q9BZK7,P56589,P04062,Q04656,Q8N6M0,Q15392,Q96ST3,Q14739,P60866,O00192,P08069,Q96EK5,Q9BUF5,P21359,Q5JPH6,Q5KU26,P62857,Q9H490,Q9C0B1,Q93074,Q9H3S7,Q13620,Q14671,Q8NCH0,Q7LGA3,Q9UBM7,Q15555,P62258,Q9Y263,Q9Y487,Q7LG56,P40855,Q9NX62,O43505,O96028,Q9ULC3,P63241,Q96PZ0,Q15125,Q8N3R9,Q15427,Q9UBB6,Q8NCM8,Q01105,Q96RR1,P19022,P43034,P31749,O60934,P40763,O75844,Q9H9S5,O95831,Q99643 58 +Hyperpigmentation of the skin 0.3259682030061581 0.3351747218083135 0.7374932893416255 1.0 1.0 94 P04062,Q96ST3,P51648,Q14739,P21359,Q93074,Q9H3S7,Q13423,Q13472,Q9NX24,Q8ND04,Q7LGA3,Q15555,O60333,Q96PZ0,Q8N3R9,P10644,P31749,O60934,P29992,O75844,Q99643 22 +Abnormal cell morphology 0.4132956140364419 0.3351186188986415 0.7375356082790412 1.0 1.0 6 P54098,Q7LG56 2 +Recurrent herpes 0.4015933903806547 0.3330788532767068 0.7390747615184492 1.0 1.0 2 P42224 1 +Abnormality of ocular smooth pursuit 0.4401992869708846 0.3324295815384914 0.739564904564471 1.0 1.0 20 O14773 1 +Thickened nuchal skin fold 0.4317299716636687 0.3311091201058397 0.7405620629867498 1.0 1.0 15 Q9NUM4,Q15125,P40855 3 +Temporal pattern 0.4167081065492346 0.3297202184407904 0.7416113752001496 1.0 1.0 8 O60313,P04062 2 +Aggressive behavior 0.3911558084364784 0.3291796299486571 0.742019918684155 1.0 1.0 77 Q9UBM7,P49591,O00462,P17480,Q10713,Q9NQ11,P35670,Q93074,Q6IA86,Q9H9B1,O75503,Q96ST3,P54802,Q9NUM4,Q7LBC6,Q15125,Q96PZ0,P35270 18 +Abnormal larynx morphology 0.449785312017535 0.3289087107367587 0.742224690092754 1.0 1.0 30 Q9UHX1,Q69YQ0,Q96HY6,P07602,O43909,Q13510,Q14739,O00192,Q15427 9 +Acute phase response 0.4496416131863527 0.3282750833893046 0.7427036818153225 1.0 1.0 30 P21359,P41440,P28070,P10644,O15460,O60333,P01889 7 +Abnormality of the autonomic nervous system 0.4311701690498355 0.3282027357900949 0.7427583794532291 1.0 1.0 61 Q9UBM7,P41440,Q10713,P07602,Q04446,P06280,Q9H0U9,Q96RR1,Q04656,P04062,O43464,P07686,P42892,O60333,Q15427,Q7Z3E5,Q96EK5 17 +Aortic regurgitation 0.4453555009774635 0.3281028887115124 0.7428338699150112 1.0 1.0 25 Q9UHX1,O00754,Q9H9B1,O75844,P01889,Q9NZ08 6 +Axonal regeneration 0.4028925619834658 0.327324533963979 0.7434224381577617 1.0 1.0 3 P07196,P54577 2 +Scotoma 0.4286659256440242 0.3264394376989977 0.7440919033110747 1.0 1.0 14 Q9Y287,P04439 2 +Abnormality of the antihelix 0.4221893491124385 0.3249185388179679 0.7452427255631271 1.0 1.0 11 Q08J23,P27635,Q9UDR5,O14656,Q5SRE5,P16435,Q15042,P98175,Q9H2M9,P21333 10 +Severe cytomegalovirus infection 0.4017119244391985 0.3230996492912379 0.7466197758554454 1.0 1.0 3 Q7L590,Q9H0U3 2 +Stroke 0.4501924735562613 0.3218294513189191 0.7475819013992231 1.0 1.0 34 P21359,P06280,Q9Y4U1,P05067,P00403,Q15056,O43709 7 +Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells 0.3983475951608136 0.3215173809513073 0.747818342811728 1.0 1.0 2 Q05655 1 +Coombs positive hemolytic anemia 0.3983475951608136 0.3215173809513073 0.747818342811728 1.0 1.0 2 Q05655 1 +Follicular hyperplasia 0.3983475951608136 0.3215173809513073 0.747818342811728 1.0 1.0 2 Q05655 1 +Abnormal proportion of double negative alpha beta regulatory t cell 0.3983475951608136 0.3215173809513073 0.747818342811728 1.0 1.0 2 Q05655 1 +Increased b cell count 0.3983475951608136 0.3215173809513073 0.747818342811728 1.0 1.0 2 Q05655 1 +Abnormality of tibia morphology 0.4327933437904787 0.3214841514168015 0.7478435207047887 1.0 1.0 17 P21359,Q04656,Q93063,O95831 4 +Cold induced muscle cramps 0.4011216056670559 0.3209948008289255 0.7482143309336025 1.0 1.0 3 P41250,Q9NR77 2 +Bundle branch block 0.4271902964801616 0.3207353326352579 0.7484109691502501 1.0 1.0 14 P19022,P06280 2 +Medulloblastoma 0.4117918711209777 0.3204647671162789 0.7486160349151181 1.0 1.0 7 O60934 1 +Dysmetria 0.4218535917021574 0.3203326928073448 0.7487161425228033 1.0 1.0 65 Q10713,O60313,O75503,O14773,O75787,P07384,P21359,Q13472,Q14671,Q8N183,O43292,Q8IV08,O94886,Q6P4A7,O43709,P41440,Q99519,P54098,Q15056,Q9NUM4 20 +Impairment of activities of daily living 0.4407118412502081 0.3202755506322928 0.748759455562761 1.0 1.0 54 Q9NQ11,P07602,Q93074,P07686,P31749,Q10471,P07384,Q99720 8 +Distal sensory loss of all modalities 0.4030115146147088 0.3175747755306072 0.7508075105397121 1.0 1.0 4 O15270,O15269,P48643 3 +Thick lower lip vermilion 0.4464152568438349 0.3142716157492122 0.7533147542470711 1.0 1.0 47 Q99519,P04066,P06280,Q93074,P15586 5 +Abnormal placenta morphology 0.4147084065135233 0.3136350965831276 0.7537982003357389 1.0 1.0 9 P16278 1 +Prenatal maternal abnormality 0.425275249692077 0.3133795998811895 0.7539922811649094 1.0 1.0 14 Q8TAA9,P31153,P22570,O43567,Q14739,O43772 6 +Abnormality of skeletal maturation 0.3237016571816462 0.3126648675650818 0.7545352898195015 1.0 1.0 94 Q99519,Q8WVQ1,O43909,Q14108,P04062,P10644,Q15056,O43567,P08069,O96028,P48449 11 +Preaxial foot polydactyly 0.4070996568585545 0.3125096151569462 0.754653256885848 1.0 1.0 6 O96028 1 +Incomitant strabismus 0.4304469116327789 0.312264019152574 0.7548398823626306 1.0 1.0 17 Q7LGA3,O60313,Q9H3S7,Q96PZ0 4 +Antiphospholipid antibody positivity 0.3984651711924463 0.3115863162515096 0.7553549349299093 1.0 1.0 3 P42224,Q05655 2 +Nail dysplasia 0.4484554626209355 0.3113859483660154 0.7555072348819314 1.0 1.0 36 P23229,P10321,Q93063,P42892,O43567 5 +Increased total bilirubin 0.4012400354295912 0.3112688969366907 0.7555962102590519 1.0 1.0 4 P08237,Q9UGP8,P14314 3 +Abnormal ventricular septum morphology 0.2818212698624196 0.3104429704595283 0.7562241214085583 1.0 1.0 161 Q8TD19,Q69YQ0,P56589,Q7KZN9,Q8N6M0,P98164,P42892,Q14739,P60866,P08069,O00192,P21359,P62857,P06280,Q9C0B1,Q93074,Q8ND04,Q8N183,Q9UBM7,P40855,Q7LBC6,O96028,Q9ULC3,Q15427,O43709,Q8WVQ1,Q93063,Q15056 28 +Waddling gait 0.4448107079909723 0.3103035378699554 0.756330141023517 1.0 1.0 29 Q8WVQ1,Q13510 2 +Abnormality of vitamin b12 metabolism 0.4244430338373509 0.3101997653907822 0.7564090489279414 1.0 1.0 14 Q9Y4U1,O43567 2 +Aplasia hypoplasia involving the metacarpal bones 0.4438135546406818 0.3094839563947286 0.7569534144870105 1.0 1.0 28 Q8WVQ1,Q93063,P10644,Q9NX62,Q9H173 5 +Calvarial skull defect 0.4087535685267944 0.3094061698304665 0.7570125776584355 1.0 1.0 7 O96028 1 +Prominent occiput 0.4279152257652746 0.3092093021003502 0.7571623183523073 1.0 1.0 16 Q93074,Q04656 2 +Abnormality of the lymph nodes 0.4481574828268105 0.3091107214591022 0.7572373037649598 1.0 1.0 40 Q9BZK7,P28070,P10644,O15460,Q13510,P01889,P40763,Q9NZ08 8 +Increased circulating lactate dehydrogenase concentration 0.4240439701584539 0.3086785971411027 0.757566026289691 1.0 1.0 14 P10253 1 +Distal sensory impairment of all modalities 0.4031305375073937 0.3080407734263461 0.7580513071031798 1.0 1.0 5 O15270,O15269,O95140,P48643 4 +Laryngotracheomalacia 0.4031305375073889 0.3080407734263289 0.7580513071031929 1.0 1.0 5 O75369,Q14807,Q9Y4A5,Q8N766 4 +Upper extremity joint dislocation 0.4306186291642802 0.3063890032129271 0.7593084801919583 1.0 1.0 18 P10644,Q8WVQ1 2 +Thick vermilion border 0.3678499791319861 0.3063470157880932 0.7593404454022625 1.0 1.0 83 P21359,Q99519,P04066,P06280,Q01105,Q93074,Q96N67,Q15056,Q10471,P15586,Q8ND04,Q96EK5,Q96PZ0 13 +Developmental stagnation 0.4100471220531639 0.3052356611238553 0.7601866738854235 1.0 1.0 8 P16278 1 +Panhypogammaglobulinemia 0.4022445363260566 0.3048933257032838 0.760447399218287 1.0 1.0 5 Q15477,Q6PGP7,P19447,P18074 4 +Bilateral microphthalmos 0.4022445363260557 0.304893325703281 0.7604473992182892 1.0 1.0 5 Q13428,Q9UHX1,P19447,P18074 4 +Resting tremor 0.4346388520949443 0.3042024264335615 0.7609736763621224 1.0 1.0 21 Q9NQ11,P07602,Q96RR1,P04062,O75787 5 +Eeg with generalized slow activity 0.4163307376006626 0.3029869556424783 0.7618998025398 1.0 1.0 11 O43567,O75503 2 +Acanthosis nigricans 0.4140170835220382 0.3026617716740044 0.7621476338774713 1.0 1.0 10 Q96MF7,P31751,Q13620,P28070 4 +Impaired tandem gait 0.4295854857593573 0.3023461688762524 0.7623881864762005 1.0 1.0 18 Q7LGA3,O75787,Q9H3S7,Q96PZ0 4 +Retinal atrophy 0.4436778568270471 0.3022495185824196 0.7624618579672204 1.0 1.0 30 Q7LGA3,Q10713,P04062,Q9H3S7,P51648,Q9H9S5,Q96PZ0,P04439 8 +Neonatal onset 0.434111204270974 0.3020894922358794 0.7625838424576397 1.0 1.0 21 Q13277,Q9UDY2,O75787,P40763,Q15904 5 +Antinuclear antibody positivity 0.3985828166519078 0.3018977633259478 0.7627300008652589 1.0 1.0 4 Q9Y5L0,P53621,Q05655 3 +Abnormal urinary color 0.401358535144722 0.3017576768077251 0.762836796695102 1.0 1.0 5 P53004,P36551,P08397,P06132 4 +Sudden death 0.4431484361078652 0.29996527362375 0.7642036441936206 1.0 1.0 30 P04114,Q9Y4J8,Q9Y4P3,O15460,P31749,P14923,Q15056,P15924,P01889,Q8NFV4,Q14126,P50416,O43709 13 +Neoplasm of the skin 0.4451442953344497 0.299620331268061 0.7644667741652353 1.0 1.0 44 P21359,P53634,P31749,Q07954 4 +Abnormality of circulating fibrinogen 0.4152946569509671 0.2991613095322014 0.7648169686852067 1.0 1.0 11 P10644,P40763 2 +Pectus carinatum 0.4457936280285412 0.2978340331798922 0.7658298379279358 1.0 1.0 38 P21359,Q99519,P08236,O00754,P16278,Q9H173 6 +Neoplasm of the thyroid gland 0.4417800674936922 0.2973127165538907 0.7662277739584167 1.0 1.0 29 Q9UPY3,Q04656,P10644,P31749,P42892,Q99643 6 +Abnormal cry 0.4188132339978316 0.2964812550529324 0.7668625801281928 1.0 1.0 13 Q9H0U9,Q69YQ0,Q13510 3 +B cell lymphoma 0.3993841737246288 0.2948130301643858 0.7681367119787696 1.0 1.0 5 O60934,Q05655 2 +Pulmonary artery dilatation 0.4217074571155439 0.2925301128646301 0.769881339530534 1.0 1.0 15 Q7LGA3 1 +Striae distensae 0.4085906870518747 0.2913531351145287 0.7707812532053209 1.0 1.0 9 Q13620,P10644,Q15334 3 +Paraparesis 0.4415346677292807 0.2900855845627043 0.7717507637303274 1.0 1.0 31 P21359,Q9NQ11,Q5XKP0,P04062,Q13510,O75787 6 +Protruding tongue 0.4208298835997413 0.2892236798830408 0.7724102119141092 1.0 1.0 15 Q99519,O15111,Q9H9B1,Q9C0B1 4 +Aplasia hypoplasia involving the pelvis 0.4187632537323035 0.2887743626000926 0.772754052351246 1.0 1.0 14 O96028,Q8WVQ1,O95831 3 +Abnormal cerebral vascular morphology 0.4052315015763045 0.2885516038326972 0.772924535236492 1.0 1.0 70 P21359,P04114,P06280,Q9Y4U1,Q04656,P05067,P04062,P10644,P31749,P00403,O60333,Q15056,O75844,O43709,P10253,Q99643 16 +Urethral stenosis 0.425786984771678 0.2876212235414564 0.773636697042543 1.0 1.0 18 P23229,Q9BUR4,Q9Y4P3,Q15056,Q9NX24,O43709 6 +Microdontia 0.4377105389103208 0.2876064514651809 0.7736480059020769 1.0 1.0 27 Q7LGA3,Q15555,Q9Y487,Q9Y4P3,P61586,Q9H1A4,Q15056,Q9NX24,O43709 9 +Increased connective tissue 0.4050099335104897 0.2871586948417599 0.7739908117005194 1.0 1.0 8 P31751 1 +Midface retrusion 0.368856172943666 0.2859873284607863 0.7748878268426282 1.0 1.0 82 P21359,Q8WVQ1,Q8TD16,Q9BZK7,P62857,Q9Y487,Q93074,P10644,O00754,Q9H9B1,P98164,O95831,O43567,Q9ULC3,Q15125 15 +Lethal skeletal dysplasia 0.3909508449768899 0.285548118203184 0.7752242451302145 1.0 1.0 3 Q14739 1 +Abnormal pelvis bone ossification 0.3909508449768899 0.285548118203184 0.7752242451302145 1.0 1.0 3 Q14739 1 +Gray matter heterotopia 0.4402427403861459 0.2845268660502229 0.7760066483044838 1.0 1.0 31 Q9UBM7,Q93074,P19022,P43034,P31749,P23258,Q7Z3E5,O43505,Q9H9S5,P35606 10 +Cholestasis 0.378729417292127 0.284219622898104 0.7762420783995605 1.0 1.0 79 Q8TD19,P56589,O15118,Q04656,O75787,P38571,Q5JPH6,Q8NB49,P11413,Q15904,Q9UBM7,Q9Y4U1,Q13510,P40855,P61916,P00374,Q9UDY2,P35670,P10644 19 +Reduced subcutaneous adipose tissue 0.4111678835547985 0.2840857344860923 0.7763446790201254 1.0 1.0 11 P41227,O75844,P08069,Q13472 4 +Small hand 0.4411959279540752 0.2836223494735223 0.7766998077523448 1.0 1.0 33 O15111,Q69YQ0,Q8WVQ1,Q96ST3,Q10471,Q14671,P08069,Q96EK5 8 +Hypoplasia of the frontal lobes 0.4038330696937359 0.2829914700569461 0.7771833757662381 1.0 1.0 8 Q9UBM7,P35606,P22570 3 +Abnormal trabecular bone morphology 0.4036914818726836 0.2824915694601234 0.7775666100566936 1.0 1.0 8 Q9NX24,Q9BUR4 2 +Abnormal elasticity of skin 0.4155398361322538 0.2810203084858419 0.778694823320055 1.0 1.0 65 Q9BZK7,Q15334,Q04656,P04062,Q9H9B1,O75787,Q9Y3D3,Q9Y4P3,Q13620,Q8NFV4,Q15904,Q8NCH0,Q15555,Q9Y487,O43709,Q9UHX1,P10644,O96000,O00754,Q15056,Q13126,O75844 22 +Abnormal shoulder morphology 0.4410378230428893 0.2777722338058878 0.781187206912306 1.0 1.0 36 Q7LGA3,Q8N3R9,Q9Y4P3,Q04656,Q9H3S7,Q8N6M0,Q13620,P41227,Q15056,Q8NFV4,Q6W2J9,O43709,Q96PZ0 13 +Abnormal circulating ige level 0.3995942247327989 0.2769102595318987 0.7818490145663299 1.0 1.0 7 P40763 1 +Large for gestational age 0.4044795142037787 0.276700946771987 0.7820097448280652 1.0 1.0 9 P31751 1 +Vertebral fusion 0.4110719199470584 0.2757874493293928 0.7827113240062529 1.0 1.0 12 O96028,Q8TAA9,Q9H9S5 3 +Congestive heart failure 0.410318277506082 0.2754160297952044 0.7829966301311466 1.0 1.0 67 P16278,P21359,P06280,Q9Y4J8,Q9Y4P3,Q8NFV4,Q9H2M9,Q70HW3,Q96MF7,P10253,Q15555,P00403,O60333,P15924,Q9H2U2,O43709,P09493,P10644,Q15056,P29992,Q99643 21 +Albinism 0.3875442739079135 0.2740330432596816 0.7840592283992043 1.0 1.0 3 O00203,Q86YV9 2 +Glycosuria 0.4054295669973771 0.2717029002778997 0.7858504710623766 1.0 1.0 10 P35670 1 +Joint contractures involving the joints of the feet 0.4049431723644928 0.2699839678159232 0.7871725875958022 1.0 1.0 10 Q8IWS0,P15924,P63241,Q6W2J9 4 +Chronic constipation 0.4331417209241956 0.2687988608473515 0.7880844700048892 1.0 1.0 27 Q7LGA3,P04062 2 +Abnormal conjugate eye movement 0.2767361453170737 0.2652095126181286 0.790848067206984 1.0 1.0 319 Q69YQ0,Q9BZK7,P07602,Q10713,Q7KZN9,P56589,O15118,P04062,O60313,Q15392,Q96ST3,Q14739,P60866,Q9H173,P08069,O00192,P21359,Q5KU26,P62857,Q9H490,Q93074,Q9H3S7,P61586,P51797,Q8ND04,Q96MW5,Q8N183,Q8NCH0,Q7LGA3,Q9UBM7,Q9Y467,Q9Y487,P40855,P61916,Q7Z3E5,O96028,O43709,Q99720,Q96PZ0,Q14203,Q99519,Q9NQ11,Q9UBB6,Q96RR1,P54098,P19022,Q93063,O00754,P10644,P31749,O96000,Q15056,Q10471,Q9H9S5 54 +Hyperostosis 0.4139685070398253 0.2637877304594847 0.7919434894890272 1.0 1.0 15 O00754,P31749 2 +Hand muscle weakness 0.407503605222609 0.2629916948540639 0.7925569804114652 1.0 1.0 12 P54098,Q8TD16,Q14203 3 +Inflammatory abnormality of the eye 0.4379426722396654 0.2628342437842246 0.7926783404647357 1.0 1.0 37 P28070,P51648,Q14739,P01889,P29992,Q9NX24,Q9NZ08,P02786,P04439 9 +Generalized hypopigmentation of hair 0.4000352550055288 0.2611625596204447 0.7939671494919605 1.0 1.0 9 Q9NX24,P10644 2 +Malabsorption 0.4272792818159804 0.2606392150467594 0.794370745375083 1.0 1.0 56 Q9Y6B6,Q9BUR4,Q9UDY2,P56589,P06280,Q9Y4P3,P54098,Q04656,Q9NZ08,P40855,Q15056,Q14739,P60866,P01889,Q8NFV4,Q9NX24,P38571,O43709 18 +Encephalocele 0.4165420923189586 0.259342336359699 0.7953711167917965 1.0 1.0 17 O43505,Q9H9S5,Q7Z3E5 3 +Hyperpituitarism 0.4164466430806414 0.2589896420361284 0.7956432323657907 1.0 1.0 17 P31749 1 +Falls 0.4016120855332641 0.2583143023301646 0.7961643490822803 1.0 1.0 10 Q9NQ11 1 +Prominent nose 0.4243736529993436 0.2582349603293323 0.7962255782325516 1.0 1.0 22 P56589,O43909,Q93074,P40855,O60934,Q8ND04 6 +Abnormality of the palpebral fissures 0.2725478394160592 0.2570582854184944 0.7971337790965265 1.0 1.0 235 Q69YQ0,Q9BZK7,P56589,Q04656,Q8N6M0,Q15392,Q9H9B1,P98164,Q96ST3,Q8IWS0,Q6W2J9,O00192,P08069,Q96EK5,Q9UQR1,P21359,Q5KU26,P62857,Q9Y4P3,Q93074,Q92917,Q9BXW9,Q9H3S7,Q13620,P61586,Q8NFV4,Q9H2M9,Q8WYQ5,Q8NCH0,P35606,P42695,Q7LGA3,Q8NC96,Q9UBM7,Q15555,Q13555,P60953,P62258,Q9Y487,P40855,P41227,O96028,Q15427,O43709,P63241,Q96PZ0,Q15125,Q8N3R9,Q9UHX1,P19022,P43034,P31749,Q9GZZ9,Q15056,Q10471,O60934,O75844 57 +Short palm 0.4275443894086761 0.2552073021657695 0.7985629914572017 1.0 1.0 25 Q15555,Q9UHX1,Q13555,Q9BZK7,Q04656,P10644,Q13620,Q96ST3,Q9H173,P08069 10 +Deviation of the hallux 0.4353760413673935 0.2543325939918993 0.7992386211062481 1.0 1.0 35 Q7LGA3,Q8N3R9,Q9Y4P3,P04062,Q9H3S7,P31749,Q15056,Q15427,O43709,Q96PZ0 10 +Flared nostrils 0.3845476791665271 0.2542224791621235 0.7993236851001306 1.0 1.0 4 Q96ST3 1 +Broad toe 0.4323829364206616 0.2512992005334448 0.8015827932182424 1.0 1.0 31 Q7LGA3,Q8N3R9,Q9UHX1,Q93074,Q9H3S7,P61586,P41227,Q6W2J9,Q15427,Q15125,Q96PZ0 11 +Abnormality of the tonsils 0.3894256380917573 0.2512193363005308 0.8016445356337105 1.0 1.0 6 P31751 1 +Lower extremity joint dislocation 0.3740386917381796 0.2492564655708231 0.8031624041412251 1.0 1.0 79 Q8TD16,Q04656,Q9H173,O00192,Q969X5,Q9Y4P3,Q9BXW9,Q9NQX3,Q9UBM7,P62258,Q9Y487,Q9NX62,O96028,Q15427,O43709,Q15125,Q9UHX1,Q8WVQ1,P43034,P31749,Q15056,O75844,Q9H9S5 23 +Abnormal tricuspid valve physiology 0.4154236796085097 0.2486051829729889 0.8036661989195126 1.0 1.0 18 Q15904,P10644 2 +Tooth malposition 0.3127013967649948 0.2485841493502958 0.8036824706818129 1.0 1.0 95 Q69YQ0,Q9BZK7,P34059,P51571,Q96N67,P16278,Q96ST3,Q14739,Q6W2J9,Q9Y4P3,P08236,Q93074,Q13620,P61586,Q8NFV4,Q9H2M9,Q9UBM7,P60953,O43709,Q01105,P10644,O00754,P51798,Q15056,O75844 25 +Esophageal stenosis 0.393734555614282 0.2481413762409493 0.8040250228901007 1.0 1.0 8 Q9NX24,P01889 2 +Aplasia hypoplasia involving bones of the upper limbs 0.2766237217527503 0.2464831720146499 0.8053082294685976 1.0 1.0 147 O15111,Q69YQ0,Q9BZK7,Q04656,Q9H1A4,Q8IWS0,Q96ST3,Q14739,P60866,Q9H173,Q6W2J9,P08069,Q96EK5,P46783,P62857,Q93074,O43909,Q9BXW9,Q13620,Q14671,Q9UBM7,Q15555,Q13555,Q9Y297,Q32P28,Q13510,Q9NX62,O96028,Q15427,Q9UHX1,Q8WVQ1,Q8NCM8,Q93063,P10644,P51798,Q10471,O75844,O95831 38 +Enlarged kidney 0.390653326253613 0.2464699263747424 0.8053184817651808 1.0 1.0 7 Q8TD19,Q9UBS4 2 +Insomnia 0.4103700544836834 0.2436901101696821 0.8074708334457172 1.0 1.0 16 Q9Y4P3,O43464,Q15056,Q10471,O43709,Q14203 6 +Abnormal penis morphology 0.2732877284809603 0.2436560526917413 0.8074972124918249 1.0 1.0 209 Q69YQ0,Q10713,Q9BZK7,P56589,Q9UBX3,Q9H0U9,P51571,Q9H9B1,Q8IWS0,Q96ST3,P42892,O75787,P60866,Q6W2J9,O00192,Q96EK5,P46783,P62857,O43395,Q9Y4P3,Q93074,Q9BXW9,P50213,Q13620,Q8NFV4,Q9H2M9,Q9NX24,Q8ND04,Q9UBM7,Q15555,P60953,P62258,O94886,P40855,P61313,P41227,O75381,Q7LBC6,O43505,O96028,O43709,P48449,Q9UHX1,Q9BUR4,Q8NCM8,O15078,P19022,Q93063,P43034,O15344,P31749,P10644,O43172,Q15056,O75844,Q9H9S5,Q99643 57 +Increased nuchal translucency 0.4122557137573888 0.2436524766447143 0.8074999823135389 1.0 1.0 17 Q9UBM7,Q9Y4P3,O43709,Q15056 4 +Mood swings 0.3812936723642594 0.2436259787823423 0.8075205062671986 1.0 1.0 4 Q8WYQ5,Q13620 2 +Areflexia 0.3165838070206731 0.2431282197555507 0.8079060707730621 1.0 1.0 94 P41440,Q9Y6B6,Q8TD16,P56589,Q96RR1,P54098,Q6UWE0,Q13510,Q15041,Q9H9S5,O60333,O75787,Q9H173,O43505,P10253,O95831,Q969X5 17 +Overriding aorta 0.3968602068629806 0.2419827119504017 0.8087935590698181 1.0 1.0 10 Q9Y4P3,Q8TD19,O43709,Q15056 4 +Abnormality of urine catecholamine concentration 0.399012482182224 0.2412512006276366 0.8093604301741983 1.0 1.0 11 P21359,O60333 2 +Thickened calvaria 0.3941693176306265 0.2411478572113386 0.8094405223061707 1.0 1.0 9 O00754,P16278 2 +Muscle fibrillation 0.4095653277417129 0.2408047785528814 0.8097064258419782 1.0 1.0 16 Q9H0U9,Q13510 2 +Neoplasm of the rectum 0.4129874071416363 0.2396893036495706 0.8105711277163248 1.0 1.0 18 Q9UPY3,P31749,Q99643 3 +Arteriovenous malformation 0.3909374282697726 0.238785150046567 0.8112721857360361 1.0 1.0 8 P31749 1 +Medial flaring of the eyebrow 0.3796363747091824 0.2382977564426657 0.8116501613362257 1.0 1.0 4 O15078,Q96ST3 2 +Abnormality of the voice 0.275540125921827 0.2382925402960036 0.811654206715462 1.0 1.0 144 Q69YQ0,Q99643,O60313,Q9H0U9,P04062,Q96ST3,O75787,Q9H173,P08069,O00192,P21359,Q96HY6,Q93074,Q7LGA3,Q9Y487,Q13510,O60333,O43709,Q96PZ0,Q14203,Q9BQP7,Q99519,Q96RR1,P54098,Q15056,O75844,Q9H9S5,Q4J6C6 28 +Aplasia hypoplasia involving the nose 0.4243598210600047 0.2380431900047488 0.8118475960392924 1.0 1.0 26 Q5KU26,Q93063,P10644,Q96ST3,O75844,Q8WYQ5,P63241 7 +Relative macrocephaly 0.4310701171868794 0.2378830897625893 0.811971771497491 1.0 1.0 34 P21359,Q7LGA3,Q15392 3 +Infectious encephalitis 0.3979308701115999 0.237557851281921 0.8122240444968838 1.0 1.0 11 Q9NZ08,P01889 2 +Abnormal carotid artery morphology 0.4141262865307266 0.237449622623888 0.8123079969687317 1.0 1.0 19 P21359,P04114,Q9Y4P3,Q04656,Q9BXW9,P31153,Q15056,O75844,O43709 9 +Abnormality of malar bones 0.3973373803429691 0.2370972933343852 0.8125813121161096 1.0 1.0 70 P21359,Q8WVQ1,Q9BZK7,Q9H490,Q9Y487,Q93074,P10644,O00754,Q9H9B1,P98164,O95831,Q14739,O60934,O00192,Q9ULC3,Q15427,Q15125 17 +Abnormality of the cerebral subcortex 0.2673489643182473 0.2365815836024795 0.8129814088086398 1.0 1.0 392 Q69YQ0,Q10713,P07602,Q04446,O60313,P17900,Q15392,O75503,P98164,Q96ST3,O00584,Q9Y3D3,P49591,P17480,P15311,Q5KU26,Q9H3S7,Q13620,P10253,Q7LGA3,Q8NC96,Q9Y263,Q7LG56,O43567,O43505,P48449,Q8N3R9,Q9UHX1,Q9HC07,Q9NQ11,Q8NCM8,O75489,O00754,P43034,Q8TD16,P04062,Q8N6M0,P16278,P21359,Q93074,Q9UBM7,Q96PZ0,Q01105,Q96N66,Q9NUM4,Q10471,Q9UN37,Q9UBX3,P08069,Q96EK5,Q5JPH6,O43909,Q92917,Q8ND04,P62258,Q9Y4U1,Q7LBC6,O96028,Q15125,Q9UBB6,P19022,O95831,Q7KZN9,Q96N67,Q9H9B1,O75787,Q9UQR1,Q9H490,O43464,Q8N183,Q15555,P00403,Q7Z3E5,Q9ULC3,P39880,Q96RR1,P54098,Q9GZZ9,P29992,Q9H9S5 80 +Entropion 0.3924944014948445 0.2355388883865225 0.8137904991495901 1.0 1.0 9 P01889 1 +Abnormality of the pulmonary artery 0.430238527580977 0.2304918983991465 0.8177095581745941 1.0 1.0 36 Q7LGA3,Q8N3R9,P27635,O75718,Q9Y4P3,Q9H3S7,P51798,P41227,Q15056,P26196,Q8NFV4,Q6W2J9,Q8ND04,O43709,Q8WYQ5,Q96PZ0 16 +Overhanging nasal tip 0.3703157273531975 0.2284617635045277 0.8192872784131682 1.0 1.0 2 Q9H9E3 1 +Tapered finger 0.430680943136586 0.2284305345737514 0.8193115537225617 1.0 1.0 41 Q8N6M0,Q9H9B1,Q8IWS0,P42892,O43567,Q14671,Q96EK5,Q8NCH0 8 +High anterior hairline 0.4194738526522286 0.2238833409977989 0.8228480786843411 1.0 1.0 25 Q7LGA3,Q69YQ0,Q9BZK7,P98164,O96028 5 +Abnormal hair whorl 0.4149361243118831 0.2225851841835496 0.8238583684999459 1.0 1.0 22 Q7LGA3,Q93074 2 +Achilles tendon contracture 0.3955585982420077 0.2216893969362907 0.8245556847687994 1.0 1.0 12 Q9H9S5,Q8TD16 2 +Degeneration of the lateral corticospinal tracts 0.3802232361586402 0.2213280217673968 0.8248370327458561 1.0 1.0 6 O75298,Q14203 2 +Aplasia hypoplasia of the extremities 0.2742346052944849 0.2191959538443235 0.8264974072140072 1.0 1.0 190 O15111,Q69YQ0,Q9BZK7,Q04656,Q15392,Q8IWS0,Q96ST3,Q14739,P60866,Q9H173,P08069,Q96EK5,Q96HY6,P62857,Q93074,O43909,Q9H3S7,Q13620,Q14671,Q7LGA3,Q9UBM7,Q15555,Q13555,Q9Y297,Q32P28,Q13510,Q9NX62,Q5JRA6,O96028,Q9ULC3,Q15427,Q15125,Q96PZ0,Q8N3R9,Q9UHX1,Q8WVQ1,Q93063,P10644,P51798,Q10471,O75844,O95831 42 +Bilateral sensorineural hearing impairment 0.4179340253364246 0.2180365626400357 0.8274006238054443 1.0 1.0 25 P00403,Q96RR1,P07602 3 +Abnormal circulating long chain fatty acid concentration 0.3791633962894525 0.2179794075101274 0.82744515607366 1.0 1.0 6 P40855,P56589 2 +Autoimmune thrombocytopenia 0.3869704111629812 0.2173823533928703 0.8279103823524618 1.0 1.0 9 P50851,P40763,Q05655 3 +Delayed puberty 0.4241860159746011 0.2170430548090955 0.8281747917000173 1.0 1.0 51 P21359,P06280,Q14108,P04062,Q93063 5 +Abnormality of humoral immunity 0.4165608942764265 0.21696216154808 0.8282378332543496 1.0 1.0 58 P28070,O43909,P04062,Q14108,O00754,O60934,P40763,Q15904,P02786 9 +Abnormal stomach morphology 0.3694967379319601 0.2159843005595268 0.8289999850943568 1.0 1.0 79 Q9UBM7,P23229,Q8TD19,Q69YQ0,P56589,Q93074,P04062,P10644,Q04656,P31749,Q9NQX3,P40855,Q15056,Q14739,O43709,Q8NCH0,Q99643 17 +Slender finger 0.4273557279195368 0.2144347788156996 0.8302080227971047 1.0 1.0 39 P53634,Q8NCH0,Q8N6M0 3 +Impaired proprioception 0.4274120338021327 0.2139190765095206 0.8306101636596555 1.0 1.0 42 Q8IV08,Q9Y6B6,Q9NQ11,P54802,O14773 5 +Abnormality of the 3rd toe 0.3686295951385407 0.2135907497044643 0.8308662136066405 1.0 1.0 3 Q96MW5 1 +Incisor macrodontia 0.4034534587912848 0.2124153186952649 0.8317830358629703 1.0 1.0 17 Q7LGA3 1 +Cortical dysplasia 0.4217293427811981 0.2114325999349271 0.8325497206149035 1.0 1.0 30 P49591,P15311,Q9UBB6,Q96N66,P23258,Q96ST3,O43505 7 +Abnormal mitochondrial shape 0.3708296427517065 0.2107816945199496 0.8330576232959297 1.0 1.0 4 P22570,Q7Z406,P53597 3 +Urticaria 0.3892514099934515 0.2086522763376568 0.8347196980076061 1.0 1.0 11 P51648,Q15427 2 +Abnormal cellular phenotype 0.2731643917918026 0.2061096359556381 0.8367052719670163 1.0 1.0 194 P07602,Q9UBX3,Q7KZN9,P04062,O75503,O14773,O75787,P02786,Q5JPH6,P28070,O43909,Q14108,Q9Y697,P15586,Q70HW3,Q15904,Q8N183,Q13510,P00403,Q9NWW5,Q9BQP7,Q96RR1,P54098,O00754,O96000,P31749,P51798,O60934,P40763,Q4J6C6 30 +Carious teeth 0.4247143372468177 0.2055248831043546 0.8371620591241435 1.0 1.0 46 Q15555,Q9BUR4,P34059,Q9Y487,Q9Y4P3,P16278,Q9H1A4,P31749,P51798,Q15056,Q9NX24,O00192,O43709 13 +Aplasia hypoplasia of the eyebrow 0.4248670828463718 0.2047253445745214 0.8377867176796103 1.0 1.0 45 P21359,Q14574,P62857,Q96EK5,P48449,Q07954 6 +Abnormal sensory nerve conduction velocity 0.3801779021228499 0.2040535136815852 0.8383116806730406 1.0 1.0 8 Q9NR77,P54098,Q7LG56,Q9H4A3,O15269 5 +Cerebral calcification 0.4231869569066722 0.2007627111981857 0.8408841213901064 1.0 1.0 36 P05067,O00584 2 +Abnormal meningeal morphology 0.4126125892209135 0.1981624818656627 0.8429179404971752 1.0 1.0 25 P21359,Q9UHX1,Q8TAA9,Q10713,Q9UBS4,Q96ST3,O00192,Q15904,Q9H9S5 9 +Preaxial hand polydactyly 0.3905117481774735 0.1973929600553008 0.8435200383068295 1.0 1.0 13 Q9UHX1,Q8NCM8,O43909,Q9BXW9,O96028 5 +Femoral bowing 0.3856802578787967 0.1971469122638564 0.8437125730694186 1.0 1.0 11 Q8TD19,Q32P28,O00754 3 +Premature rupture of membranes 0.3722372912799304 0.1965887718790049 0.8441493578923329 1.0 1.0 6 Q9Y487,O75844 2 +Restlessness 0.4231436299967185 0.1962983297163885 0.8443766686528054 1.0 1.0 39 P04062,P05067,P10644,P42892,Q9NUM4,O43567,P48449 7 +Caesarian section 0.3658878353678848 0.1959452757077081 0.8446529992060927 1.0 1.0 4 O60313 1 +Congenital malformation of the left heart 0.3719070800043043 0.1955905868850421 0.8449306285559117 1.0 1.0 6 Q9UQR1 1 +Abnormal glycosylation 0.4056763055839805 0.1949251599305444 0.8454515372017624 1.0 1.0 21 Q9Y487,O75787,Q10471,Q15904,Q96MW5 5 +Abnormal midbrain morphology 0.3796497839547114 0.1941521532470126 0.8460567460933093 1.0 1.0 9 P04062,Q7Z3E5 2 +Calcinosis 0.368281908152603 0.1938157226357352 0.8463201755667946 1.0 1.0 5 O75844,Q14739 2 +Abnormal iris pigmentation 0.4082278314898112 0.1926433173141004 0.84723831798335 1.0 1.0 23 P56589,Q9Y4P3,P10644,P40855,P31749,Q15056,Q8NFV4,O43709 8 +Increased urine alpha ketoglutarate concentration 0.3676904902539759 0.1920585842766832 0.8476963158775463 1.0 1.0 5 P21912,P21281,P00367,P30038 4 +Myoclonic seizure 0.4103785173316169 0.1910859019162142 0.8484582927638742 1.0 1.0 59 O43292,Q99519,Q9UBB6,P07602,Q01105,O43909,Q5XKP0,P04062,Q13510,Q96N66,P16278,O75503,P07686,P40763 14 +Fibular hypoplasia 0.3665198225204817 0.1885994539243179 0.8504067608376256 1.0 1.0 5 Q15427 1 +Impaired distal proprioception 0.3632119681657524 0.1880977212967371 0.8508000473578903 1.0 1.0 4 Q96RR1 1 +Ambiguous genitalia 0.4083815459863971 0.1878567863676759 0.8509889190325084 1.0 1.0 24 Q9UBM7,Q9H0U9,Q15392 3 +Progressive sensorineural hearing impairment 0.3772824315199943 0.1868482718775455 0.851779597855945 1.0 1.0 9 P00403,O60313 2 +Depressed nasal ridge 0.4065421853890309 0.1866319017523628 0.8519492522173613 1.0 1.0 23 O00754,P16278 2 +Osteomyelitis 0.3915210415367464 0.1860984635070446 0.8523675468117056 1.0 1.0 15 P51798,Q04656,P40763 3 +Hemiparesis 0.3934334663502328 0.1853582807101422 0.8529480285196307 1.0 1.0 16 Q04446,P31749,P00403,P01889,Q9NZ08 5 +Hepatic fibrosis 0.4167226703094007 0.1850108387470511 0.8532205342438757 1.0 1.0 32 Q15904,P04062,Q13510 3 +Cutaneous photosensitivity 0.4027623717098035 0.1847456017225452 0.8534285767727792 1.0 1.0 21 Q9UBM7,Q14108 2 +Smooth philtrum 0.3586430156766646 0.1825985675421683 0.8551130083824474 1.0 1.0 81 Q7LGA3,Q8N3R9,P10586,Q69YQ0,Q8WVQ1,Q9BZK7,Q8ND04,Q9Y263,Q93074,Q9Y487,Q9Y4U1,P19022,Q9H3S7,Q9H490,Q96ST3,P08069,Q9UQR1,Q96PZ0 18 +Left ventricular systolic dysfunction 0.3755029495919172 0.1814264167146323 0.8560328853890704 1.0 1.0 9 Q96RR1,P54098,O75844 3 +Language impairment 0.2675351540505262 0.1807727372284743 0.8565459630660106 1.0 1.0 287 Q10713,Q9BZK7,P05067,Q8N6M0,Q9H9B1,O75503,Q96ST3,O14773,O75787,O00584,P08069,P21359,P49591,P17480,P15311,Q5KU26,Q5JPH6,Q93074,O43909,Q9H3S7,Q13620,P15586,Q14671,Q96MW5,Q7LGA3,Q8NC96,P55263,Q15555,O43292,Q9Y263,Q9Y487,Q6P4A7,Q7LBC6,Q7Z3E5,Q15427,P48449,Q96PZ0,Q8N3R9,Q9UHX1,P41440,Q9UBB6,Q01105,Q93063,P43034,O00754,P22570,P10644,Q96N66,Q6IA86,Q9NUM4,O14949,Q10471,Q9GZZ9,P35270,Q9UN37,Q9H9S5,O95831 57 +Long palpebral fissure 0.4089339316046445 0.1798382710689801 0.8572795374400635 1.0 1.0 26 Q5KU26,Q8N6M0 2 +Abnormality of the hepatic vasculature 0.3770112155312424 0.1780091956634217 0.8587157539864141 1.0 1.0 10 P38571,Q9UDY2,Q10713 3 +Heart block 0.4065833931936515 0.1762848480485478 0.8600701651284495 1.0 1.0 25 Q07954 1 +Abnormality of neutrophil morphology 0.3650421881068239 0.1752949614961382 0.8608478706188867 1.0 1.0 6 P41440 1 +Abnormal urine alpha ketoglutarate concentration 0.367907801418435 0.1752316856829019 0.8608975879302516 1.0 1.0 7 P00367,Q9UDR5,P21281,P30038,P21912,Q02218 6 +Upper airway obstruction 0.3611872091334376 0.1731650501667315 0.8625216945133174 1.0 1.0 5 O75844 1 +Ventricular arrhythmia 0.4179191058626825 0.1722329136816857 0.8632544231251025 1.0 1.0 42 P13473,Q9Y4J8,Q96RR1,P54098,P09493,Q7LG56,P19022,P00403,P42892,O60333,Q14126,P10253,Q99643 13 +Reduced consciousness confusion 0.2701023525499039 0.1718855316176926 0.8635275213906923 1.0 1.0 139 P07602,P04062,P05067,Q96IX5,P60866,Q9NZ08,P62857,Q9Y697,Q13423,P01889,Q8N183,Q9UBM7,Q13144,P31751,Q9Y4U1,P00403,Q9NQ11,P35670,P54098,Q96RR1,O00754,O96000,P31749,P40763,P29992,P35270,Q9H9S5 27 +Germ cell neoplasia 0.3800431196045299 0.1717945785178754 0.8635990278747561 1.0 1.0 12 P31749 1 +Abnormal gastrointestinal motility 0.4113726512396294 0.1715905840905425 0.8637594104651596 1.0 1.0 30 Q9UBM7,P06280,Q96RR1,P54098,P00403,P40763 6 +Enamel hypoplasia 0.3842332610242089 0.1699792212217866 0.8650264779001724 1.0 1.0 14 P21359,P23229,P51648 3 +Basal ganglia calcification 0.3684409569403575 0.1685496876857787 0.8661508576266213 1.0 1.0 8 P00403,P29992 2 +Cubitus valgus 0.3881558145799549 0.1682531449986834 0.8663841331604027 1.0 1.0 16 Q9H173 1 +Preaxial polydactyly 0.3901027723741167 0.1677037336655965 0.8668163587537039 1.0 1.0 17 Q9UHX1,Q8TD19,Q8NCM8,O43909,Q9BXW9,Q9ULC3,O96028 7 +Venous thrombosis 0.3899411022362933 0.1671828522493524 0.8672261764493541 1.0 1.0 17 Q9NZ08,P10644,P01889,P31749 4 +Narrow face 0.4163685764668803 0.1667932862108883 0.8675327015146928 1.0 1.0 40 Q7LGA3,Q8N3R9,Q9Y4P3,Q93074,Q04656,Q9H3S7,Q96ST3,Q15056,P26196,Q8NFV4,Q6W2J9,O43709,Q96PZ0 13 +Abnormal thrombosis 0.41004534449016 0.1666358907957595 0.867656551740122 1.0 1.0 30 Q9BZK7,Q9Y697,Q9NZ08,O15460,P10644,P31749,P01889,P40763,P38571 9 +Hypercalcemia 0.4023272377813957 0.1664463653151869 0.8678056885616432 1.0 1.0 24 P21359,Q9Y4P3,O60333,Q15056,P29992,O43709,Q99643 7 +Hirsutism 0.4056354914635204 0.1658838322684647 0.8682483711890412 1.0 1.0 59 P08236,P16278,P31749,P54802,P15586,P53634 6 +Facial edema 0.4075760132318464 0.1657697796772024 0.8683381293587764 1.0 1.0 28 Q99519,P28070,Q9Y5K6,Q9Y4P3,P52565,O43707,Q9H1A4,Q15056,Q8NFV4,Q9P2R3,O43709 11 +Primary adrenal insufficiency 0.3847295646640949 0.1643903870001589 0.8694238306900897 1.0 1.0 15 Q13423,P40855,P31749 3 +High pitched voice 0.3769283926156289 0.1623182478579092 0.8710552455205047 1.0 1.0 12 Q93074,P08069 2 +Portal fibrosis 0.3537073768907132 0.1613057771233911 0.8718525733602693 1.0 1.0 4 P55263 1 +Difficulty walking 0.3645427281284168 0.1597399872181129 0.873085900092162 1.0 1.0 78 Q9NQ11,P07602,P35670,Q13510,P31749,O14773,Q99720 7 +Oral pharyngeal dysphagia 0.382383790205172 0.157097593998573 0.8751679337500375 1.0 1.0 15 Q13510 1 +Insulin resistant diabetes mellitus 0.3671709182485392 0.156834254059687 0.8753754760625778 1.0 1.0 9 P40763,P31751 2 +Ventricular hypertrophy 0.4139560211771063 0.1559321497030424 0.8760865034648015 1.0 1.0 41 P06280,Q9Y4J8,Q96RR1,P54098,Q7LG56,Q9H9S5,P10253,P00403,O75787,O75844,Q07021 11 +Absent or minimally ossified vertebral bodies 0.3513730640818534 0.154988876380011 0.8768300867001995 1.0 1.0 4 Q14739 1 +Abnormally ossified vertebrae 0.3513730640818534 0.154988876380011 0.8768300867001995 1.0 1.0 4 Q14739 1 +Aspiration pneumonia 0.4005153062771029 0.1549778549159042 0.8768387755743978 1.0 1.0 25 P04062,Q13510 2 +Hypopigmentation of the skin 0.4113527024440598 0.1549523394832844 0.8768588909610346 1.0 1.0 51 Q8IZA0,P07602,Q04656,P31749,P53634,Q15125 6 +Broad thumb 0.4075745699263385 0.1537249816227856 0.8778265864226891 1.0 1.0 31 Q7LGA3,Q8N3R9,Q93074,Q9H3S7,Q8N6M0,Q9ULC3,Q96PZ0 7 +Abnormality of the middle ear 0.2683927291684085 0.1502915059453804 0.8805346341502946 1.0 1.0 138 Q69YQ0,O15460,Q9H1A4,Q14739,Q6W2J9,O00192,P21359,P62857,O43395,Q9Y4P3,Q9H3S7,P50213,P01889,Q7LGA3,Q9UBM7,Q15555,O60333,O96028,Q9ULC3,Q15427,P63241,Q96PZ0,O43709,Q8N3R9,O00754,P51798,Q15056,Q10471,P40763,O60934,O75844,O95831,Q99643 33 +Decreased activity of mitochondrial complex iii 0.3620254245833755 0.1502420833221099 0.8805736249952085 1.0 1.0 8 Q5JPH6 1 +Bradycardia 0.374817788502313 0.1485920311021755 0.8818755614591858 1.0 1.0 13 Q96RR1,Q9H0U9,O43464,Q9H2U2,O43772 5 +Deep philtrum 0.3875704599552964 0.1465956630122932 0.8834511771138067 1.0 1.0 19 Q7LGA3,Q93074 2 +Abnormally lax or hyperextensible skin 0.411377073949682 0.1464775336162153 0.8835444241952706 1.0 1.0 47 Q15555,Q9BZK7,Q9Y487,Q04656,P04062,O96000,Q9H9B1,Q15056,O75787,Q15904,O43709,Q8NCH0 12 +Short attention span 0.2678837563841567 0.1458267570789913 0.8840581525986861 1.0 1.0 137 P07602,Q96ST3,P60866,O00192,P21359,P49591,P15311,Q93074,O43464,Q9H3S7,Q7LGA3,Q9UBM7,P00403,Q7LBC6,O43709,Q96PZ0,Q9NQ11,Q9UBB6,P19022,O00754,Q96N66,Q9GZZ9,Q15056,O60934 24 +Abnormality of corneal size 0.4116052273628855 0.1452521450996468 0.8845117966045737 1.0 1.0 44 Q15555,Q9BZK7,O43505,Q9Y4P3,O96028,Q15125,Q9H9S5,P41227,Q15056,Q8NFV4,Q9H2M9,Q6W2J9,Q9ULC3,Q96EK5,O43709,Q8NCH0 16 +Neoplasm of the larynx 0.3508564678086303 0.1448029719337161 0.8848664356952562 1.0 1.0 5 P43246,P04637,P52701,P42771 4 +Abnormality of vitamin metabolism 0.4027264045903201 0.1440647078058486 0.8854493730431052 1.0 1.0 29 O43567,Q9Y6B6,Q9UDY2,Q10471 4 +Hip dysplasia 0.4087420518007109 0.1427819024853742 0.8864624303492037 1.0 1.0 51 Q7LGA3,Q8TD16,Q04656,O43567,Q9H173,Q7LBC6,O96028,Q96PZ0 8 +Abnormal monocyte morphology 0.3396282089111817 0.1423155907350667 0.8868307322441027 1.0 1.0 2 P61011 1 +Monocytosis 0.3396282089111817 0.1423155907350667 0.8868307322441027 1.0 1.0 2 P61011 1 +Abnormal gallbladder morphology 0.4054090648162366 0.1421853447838327 0.886933607345481 1.0 1.0 32 Q69YQ0,P07602,Q9Y4P3,P04062,P40855,P47985,Q15056,Q9UN37,O00192,O43709 10 +Abnormal ovarian morphology 0.4029366395084824 0.1407096900966326 0.8880992896741231 1.0 1.0 30 P31751,Q9Y4P3,P10644,P31749,Q15056,Q8NFV4,O43709,Q99643 8 +Blue sclerae 0.3930968306742962 0.140653575547276 0.8881436217338885 1.0 1.0 23 Q8WVQ1,Q8NCH0 2 +Abnormal morphology of the radius 0.3717950349278925 0.139738602378814 0.8888665253355532 1.0 1.0 13 Q93063,Q32P28,P10644 3 +Widely spaced incisors 0.3451431945674711 0.1386485126246926 0.8897279059697942 1.0 1.0 4 Q8WXI9,P46100,Q8WVM7 3 +Brisk reflexes 0.3906659767208057 0.1383856251142843 0.889935657204916 1.0 1.0 22 Q99720 1 +Rigidity 0.3989710537264949 0.138072178271613 0.890183373671829 1.0 1.0 60 Q8NC96,P17480,Q9NQ11,P07602,Q9Y263,Q96RR1,P54098,P04062,O43464,Q9NQX3,P16278,Q15392,Q9GZZ9,O75787,Q9Y287,Q9H173,P35270,Q14203 18 +Thoracic aortic aneurysm 0.4070377743345845 0.1364055165821385 0.8915007128401746 1.0 1.0 36 Q7LGA3,Q8N3R9,Q9Y4P3,Q93074,Q9H3S7,Q9UBS4,P31153,Q15056,P01889,O75844,O43709,Q96PZ0 12 +Psychosis 0.405117756645835 0.1346258389259361 0.8929077110759425 1.0 1.0 34 Q9NQ11,Q93074,O15118,P10644,P61916,Q9NUM4,Q9Y287 7 +Esophagitis 0.3557140075114069 0.1330140074081281 0.8941823026283815 1.0 1.0 8 Q04656 1 +Flat occiput 0.3788959491171783 0.1328100881574145 0.8943435758451188 1.0 1.0 17 O00754,P40855,Q8N6M0,Q9H9B1 4 +Abnormality of the foot musculature 0.339138134592684 0.1322570192651913 0.8947810023208629 1.0 1.0 3 P50570,O14979 2 +Abnormal leukocyte physiology 0.3916944198530921 0.1312961477957459 0.8955410390264358 1.0 1.0 64 P28070,O43909,P04062,Q14108,O00754,O60934,P40763,Q15904,P02786 9 +Slender build 0.3711121769287179 0.1305795785686895 0.8961078983267177 1.0 1.0 14 Q93074,P10644,P54098 3 +Multiple prenatal fractures 0.3485856971669591 0.1302995099217019 0.8963294677907576 1.0 1.0 6 Q14739,Q32P28 2 +Talipes equinovarus 0.3417618255725169 0.1297041619951581 0.8968004895916306 1.0 1.0 84 Q9NR77,Q8TD19,Q8TD16,Q8N6M0,Q15392,Q9H9B1,Q6W2J9,O00192,Q9UQR1,Q969X5,P42356,P08236,Q96MW5,Q8NCH0,Q8TAA9,Q9Y487,O96028,Q9ULC3,Q15427,Q15125,Q8WVQ1,Q8NCM8,O00754 23 +Large face 0.3628140078596784 0.1290622919001817 0.897308359109354 1.0 1.0 77 Q7LGA3,P21359,Q10713,Q9BZK7,Q9H490,Q93074,O43909,Q04656,Q9Y4U1,Q8N6M0,P31749,Q96ST3,Q10471,Q7Z3E5,O00192,Q96PZ0 16 +Abnormal cardiomyocyte morphology 0.3340218353496607 0.1285224018648958 0.8977355711112451 1.0 1.0 2 P15924 1 +Aplasia hypoplasia of the hallux 0.3873863096645392 0.1278959009731693 0.8982313549564089 1.0 1.0 22 Q7LGA3,Q8N3R9,Q9H3S7,O96028,Q96PZ0 5 +Cutaneous syndactyly of toes 0.3407503381091564 0.1275853106850438 0.8984771564944329 1.0 1.0 4 P27635,Q6W2J9 2 +Aplasia cutis congenita 0.3594348198919093 0.1275056750335215 0.8985401818173533 1.0 1.0 10 P23229 1 +Hemivertebrae 0.3673882014104435 0.127157327627511 0.8988158787691429 1.0 1.0 13 Q15125,P63241 2 +Abnormality of the septum pellucidum 0.4066660805233991 0.1253097621054559 0.900278324060686 1.0 1.0 42 P49591,Q69YQ0,P15311,Q9UBB6,P43034,O96028,Q9H9B1,Q15392,Q96N66,Q8ND04,O43505,Q9H9S5 12 +Episodic tachypnea 0.3556461649716116 0.1250391892421042 0.9004925252578775 1.0 1.0 9 Q10713,P22695,Q7Z3E5 3 +Decreased circulating progesterone 0.3459480909088465 0.1235818865143217 0.9016463349992684 1.0 1.0 6 Q13144,Q9NR50 2 +Abnormal circulating progesterone level 0.3459480909088465 0.1235818865143217 0.9016463349992684 1.0 1.0 6 Q13144,Q9NR50 2 +Tonic seizure 0.3939535174338927 0.1228492642232493 0.9022264624740806 1.0 1.0 27 P39880,P07602,Q01105,Q96N67,Q9H3S7 5 +Bifid uvula 0.4045969608601554 0.1226542012372043 0.902380932050971 1.0 1.0 38 Q15392 1 +Pseudobulbar paralysis 0.3516132983814275 0.1222438915993742 0.9027058666228764 1.0 1.0 8 P42356,Q14203 2 +Vitiligo 0.3484495662536309 0.1219699514654967 0.9029228158147188 1.0 1.0 7 O60934 1 +Cutis laxa 0.3997954104060922 0.1219280173824025 0.9029560265044896 1.0 1.0 32 Q9Y487,Q04656,O96000,Q15056,O75787,Q15904,O43709,Q8NCH0 8 +Abnormal larynx physiology 0.3679698889580483 0.1216524722619684 0.9031742552063728 1.0 1.0 14 Q13510 1 +Prostate neoplasm 0.3511676027194726 0.1210936159392698 0.903616885708554 1.0 1.0 8 Q92878,P42771,P38398,Q6PD74,O60934,P49959,P04637 7 +Tachycardia 0.3922144800778893 0.1170779725651565 0.906798265021548 1.0 1.0 27 Q99643,P09493,P19022,P42892,P15924,P41227,O60333,Q14126,O43772 9 +Shoulder girdle muscle atrophy 0.3393384524512708 0.1156456358709225 0.9079333933291198 1.0 1.0 5 P06753,Q13049,Q9H9S5,P55072 4 +Diastema 0.3454491725768409 0.1144231802502816 0.9089023394881875 1.0 1.0 7 Q8WVM7,P46100,Q8TC12,P17612,O15347,Q8WXI9 6 +Anisocytosis 0.3420247605929075 0.1138474678764498 0.9093587092593658 1.0 1.0 6 P11413,Q8NBF2 2 +Congenital contracture 0.4037741069157745 0.112877309482299 0.910127825752201 1.0 1.0 46 P23229,Q8TD19,Q8TD16,P04062,Q15392,Q8NCH0,P40763,O75844,Q9H9S5,Q969X5 10 +Abnormality of the diencephalon 0.3970950057428653 0.1124269785084536 0.9104848651722868 1.0 1.0 32 Q96RR1,Q9Y4P3,Q92917,P19022,P54098,Q9H9S5,P31749,Q15056,Q8NFV4,O43709 10 +Abnormal waist to hip ratio 0.3438831987906743 0.11055650262723 0.9119680418326592 1.0 1.0 7 P31751 1 +Female reproductive system neoplasm 0.3817134454440541 0.1102790338133267 0.9121880844289156 1.0 1.0 22 P10644,P31749,Q99643 3 +Micropenis 0.3875868500939027 0.1091555169228618 0.913079141769256 1.0 1.0 64 Q9UBM7,Q10713,Q9BZK7,P19022,Q93063,Q9H9B1,Q8IWS0,Q96ST3,P42892,O43505,Q9H9S5,P48449 12 +Progressive muscle weakness 0.3682172585494005 0.1085647772603487 0.9135476992495286 1.0 1.0 16 P56589,Q96RR1,P54098,P40855,Q9H173,Q7Z392 6 +Delayed closure of the anterior fontanelle 0.3627359371785703 0.1072304439809781 0.9146061638603928 1.0 1.0 14 Q9Y487,Q93074,Q04656 3 +Functional abnormality of the middle ear 0.2848415622588031 0.105931928694579 0.9156363611504664 1.0 1.0 98 Q69YQ0,O15460,O00192,P21359,P62857,O43395,Q9H3S7,P01889,Q7LGA3,Q15555,O60333,Q9ULC3,O96028,Q15427,P63241,Q96PZ0,O00754,Q10471,O75844,O95831,Q99643 21 +Brachydactyly 0.3479031908298913 0.10565648372722 0.9158549079747444 1.0 1.0 81 Q69YQ0,Q04656,Q9H9B1,Q96ST3,Q14739,Q9H173,Q9Y3D3,Q9C0B1,Q93074,O43909,Q13620,P61586,Q9UBM7,Q13555,Q9NX62,Q9ULC3,P48449,Q9UHX1,Q8WVQ1,P10644,P31749,O95831,Q99643 23 +Abnormal circulating sex hormone concentration 0.3737287786010274 0.1046978720100456 0.9166155505729524 1.0 1.0 19 Q13423,P31749 2 +Pancreatic fibrosis 0.3233992328120352 0.1041038859914792 0.9170869070420506 1.0 1.0 2 O15078 1 +Hypogonadotropic hypogonadism 0.3850452380301438 0.1040580304402475 0.9171232968410998 1.0 1.0 25 Q9Y4P3,P54098,Q7LG56,P31749,P00403,Q15056,Q8NFV4,O43709 8 +Corneal ulceration 0.3337419700180309 0.1024375476647333 0.9184093816874191 1.0 1.0 5 Q96EK5 1 +Progressive external ophthalmoplegia 0.3602827892157187 0.1006653711838228 0.9198161014854908 1.0 1.0 14 Q9BQP7,Q96RR1,P54098,O60313,P00403,Q13472,Q07021 7 +Sensorimotor neuropathy 0.39354688418039 0.1001890239177759 0.9201942598137494 1.0 1.0 32 P41440,Q5KU26,P07602,O60313,P54098,Q7LG56,P00403,O95831 8 +Fluctuations in consciousness 0.3425688147913869 0.0996885136290015 0.9205916199103104 1.0 1.0 8 P04062 1 +Abnormal pupil morphology 0.3515861586587311 0.099562870024938 0.920691372734432 1.0 1.0 11 Q9NR77,O96028,Q96ST3,P61586 4 +White hair 0.335941669718041 0.0993689102570027 0.9208453665849524 1.0 1.0 6 Q9NX24 1 +Abnormal metaphyseal trabeculation 0.335941669718041 0.0993689102570027 0.9208453665849524 1.0 1.0 6 Q9NX24 1 +Oral leukoplakia 0.335941669718041 0.0993689102570027 0.9208453665849524 1.0 1.0 6 Q9NX24 1 +Highly arched eyebrow 0.3885159888882221 0.0983438640298407 0.9216592485110846 1.0 1.0 62 Q7LGA3,Q8N3R9,Q69YQ0,Q10713,Q5KU26,Q13555,O00754,Q8N6M0,Q9H9B1,Q9H3S7,P51797,Q7Z3E5,P08069,O96028,Q96EK5,Q96PZ0 16 +Deviation of the hand or of fingers of the hand 0.2545605784659837 0.0970512679509368 0.9226856806350644 1.0 1.0 111 Q8TD19,Q69YQ0,Q8TD16,Q96ST3,Q14739,Q6W2J9,P08069,P42356,Q9Y4P3,Q93074,Q9BXW9,Q13620,Q8NFV4,Q9H2M9,Q96MW5,Q9UBM7,P60953,P62258,P41227,Q5JRA6,Q9ULC3,Q15427,O43709,Q15125,Q9UHX1,Q8WVQ1,Q93063,P43034,P31749,Q15056 30 +Metaphyseal chondrodysplasia 0.3274858265172972 0.0965219984528222 0.9231060032553632 1.0 1.0 4 Q7Z2Z2,O95831 2 +Antineutrophil antibody positivity 0.3274284027162741 0.096395242571308 0.9232066704081628 1.0 1.0 4 P49327,P61011,Q05655 3 +Abnormality of the testis size 0.3900311503975532 0.0963788888046766 0.9232196583536874 1.0 1.0 30 P21359,O43505,P31749 3 +Flushing 0.3531222373900625 0.0962222358845903 0.9233440710711198 1.0 1.0 12 P21359,O60333 2 +Abnormal venous morphology 0.3886465431280489 0.096180204551009 0.9233774523986504 1.0 1.0 29 Q9Y487,Q04656,P04062,P31749,Q8ND04 5 +Abnormal incisor morphology 0.3704944152457354 0.0954826030624069 0.9239315078668116 1.0 1.0 19 Q7LGA3 1 +Multiple joint contractures 0.3724814052417118 0.094938689824492 0.9243635252587504 1.0 1.0 20 Q93074,Q92917,O75844,P41440 4 +Periorbital fullness 0.3743447158639444 0.0942700435879408 0.9248946456715672 1.0 1.0 21 Q7LGA3,Q93074,P40855 3 +Decreased circulating igg subclass level 0.3186780761286449 0.0939788932337284 0.9251259232785832 1.0 1.0 2 P17812 1 +Abnormal eosinophil morphology 0.3431917566258687 0.0936768523798073 0.9253658585284787 1.0 1.0 9 P40763 1 +Absent toe 0.3786223044151065 0.0897619626107941 0.9284763755656172 1.0 1.0 24 Q7LGA3,Q8N3R9,Q9H3S7,O96028,Q15427,Q96PZ0 6 +Exercise induced myoglobinuria 0.3311650462907739 0.088527522660425 0.9294574102906464 1.0 1.0 6 P46020 1 +Recurrent fever 0.3624284620220256 0.0861749710997867 0.9313273268476788 1.0 1.0 17 Q13510 1 +Abnormal cardiac test 0.3693075474129608 0.085993957585616 0.9314712205819792 1.0 1.0 20 P10253 1 +Transposition of the great arteries 0.3298370938958156 0.085596311871338 0.9317873304010648 1.0 1.0 6 Q9ULC3 1 +Chylothorax 0.318181818181823 0.0848147855307777 0.932408638743118 1.0 1.0 3 P52732,Q06124 2 +Very long chain fatty acid accumulation 0.3326142016637462 0.0842039272094295 0.9328942958184794 1.0 1.0 7 P40855,P56589 2 +Dyschromatopsia 0.3358594617942269 0.0840362231179699 0.9330276317332048 1.0 1.0 8 P54098 1 +Cone shaped epiphysis 0.3564871460351485 0.0839351068805329 0.9331080267803638 1.0 1.0 15 Q8NCM8,O15078,P10644,Q5JRA6,Q96MF7,O95831 6 +Abnormality of dental structure 0.353188079812224 0.0837104214113424 0.9332866711426882 1.0 1.0 78 P34059,P16278,Q9H1A4,P51648,O00192,P21359,Q9Y4P3,P61586,Q9NX24,Q9UBM7,P23229,Q15555,Q9Y487,Q5JRA6,O43709,Q9HC07,Q9BUR4,P31749,P51798,Q15056,O75844 21 +Abnormal renal morphology 0.2630135259749561 0.0821854122420715 0.9344992735444744 1.0 1.0 277 Q8TD19,Q13277,Q69YQ0,Q10713,Q04446,P56589,Q4J6C6,O15111,Q04656,Q9UNF1,Q9UBS4,Q15392,Q9H9B1,P60866,Q9NZ08,Q9UQR1,P21359,P62857,P06280,O43909,Q92917,Q14108,P01889,Q8NCH0,Q7LGA3,Q9UBM7,P23229,P04114,Q8TAA9,Q9Y4U1,P40855,P00403,O60333,Q5JRA6,O43505,Q15427,O43709,Q15125,Q9ULC3,Q9BQP7,P35670,P10644,P31749,Q15056,O60934,P29992,Q9H9S5,Q99643 48 +Wide mouth 0.3774774439866277 0.0820028431551125 0.9346444525617956 1.0 1.0 67 Q7LGA3,Q9UBM7,Q9H490,P34059,Q01105,Q93074,P16278,Q15056,P15586,Q7LBC6,Q15427,Q9UQR1 12 +Excessive salivation 0.3825867588547829 0.0815230096447215 0.9350260267285666 1.0 1.0 28 P35670,O43909,Q93074,P01889,P15586 5 +Atrioventricular canal defect 0.3409323361700148 0.0810273850798534 0.9354201739597796 1.0 1.0 10 Q9UBM7,P19022 2 +Abnormality of upper lip 0.2629057494722867 0.0802227062546904 0.9360601313807526 1.0 1.0 270 Q8TD19,O15111,Q69YQ0,Q9BZK7,P51571,P04062,Q04656,Q8N6M0,P16278,Q96N67,Q9H9B1,Q96ST3,Q6W2J9,O00192,P08069,Q96EK5,Q9UQR1,P10586,P21359,Q5KU26,Q9H490,Q9Y4P3,Q93074,O43909,Q9H3S7,Q13620,P51797,Q8NFV4,Q9H2M9,Q8ND04,Q8NCH0,P35606,P42695,Q7LGA3,Q9UBM7,Q15555,Q13555,P60953,P62258,Q9Y263,Q9Y487,Q9Y4U1,P41227,Q7LBC6,O96028,Q15427,O43709,P63241,Q96PZ0,Q8N3R9,Q9UHX1,Q9UPT5,Q8WVQ1,Q8NCM8,O75718,P19022,Q93063,P43034,O15344,P11233,P14923,Q15056,Q10471,O60934,Q9H9S5,Q4J6C6 66 +Renal dysplasia 0.3599265479624865 0.0795891725516964 0.9365640069497914 1.0 1.0 17 P23229,O43505,Q9H9S5,Q9UQR1 4 +Cafe au lait spot 0.3955348259571523 0.0792564156601612 0.9368286724646286 1.0 1.0 46 P21359,Q7LGA3,Q8N3R9,Q99643,Q93074,P10644,Q9H3S7,P31749,Q9H1A4,Q96ST3,O60333,O60934,Q13472,Q96PZ0 14 +Ventricular tachycardia 0.351377286608121 0.0778903739290826 0.937915256639808 1.0 1.0 14 P19022,P09493,P41227,P15924,Q14126,O43772 6 +Intellectual disability mild 0.2613015743453731 0.0768094617106983 0.9387751236210656 1.0 1.0 131 Q10713,P16278,Q96ST3,O00192,P21359,P49591,P15311,Q15904,Q7LGA3,O43292,Q6P4A7,Q5JRA6,Q96PZ0,P39880,Q9NQ11,Q9UBB6,Q01105,Q93063,O00754,Q96N66,P31749,Q9H9S5 22 +Infection related seizure 0.3658775660131677 0.0765719822436472 0.9389640484257002 1.0 1.0 20 P05067 1 +Abnormal shape of the occiput 0.3872032543467778 0.0752497576133765 0.9400159956950176 1.0 1.0 33 O15111,Q93074,Q04656,O00754,P40855,Q8N6M0 6 +Scapular winging 0.3733845997321598 0.0744380227604014 0.940661854923324 1.0 1.0 24 Q9Y487,P54098,Q8TD16 3 +Frontal cortical atrophy 0.3601730053285104 0.073827615502113 0.9411475529883296 1.0 1.0 18 Q7LGA3 1 +Adrenal insufficiency 0.37997376807654 0.0735022232067865 0.9414064749991302 1.0 1.0 28 P56589,Q9Y697,P40855,P31749,Q13423,Q6W2J9,P38571,Q7Z392 8 +Apraxia 0.3758009879934913 0.0729689867536243 0.9418307966853108 1.0 1.0 67 Q7LGA3,Q9NQ11,P04062,P05067,Q9NUM4,O14773,Q96PZ0 7 +Chorea 0.324025687420863 0.0722077296902679 0.942436593830472 1.0 1.0 87 P07602,P17900,Q96IX5,Q04656,P49591,P17480,Q14671,Q9BWD1,Q5XKP0,Q99720,P39880,Q9UBB6,Q9BV79,Q01105,P54098,Q96N66,Q6IA86,P35270,Q9UN37 19 +Intestinal pseudo obstruction 0.3400889776838552 0.0719485574345882 0.9426428469057736 1.0 1.0 11 Q96RR1,P00403 2 +Protruding ear 0.3935106346401626 0.0713221122210493 0.9431413970340335 1.0 1.0 47 P21359,Q93074,Q8N6M0,O43505,Q8NCH0 5 +Joint stiffness 0.3854059372234704 0.0702620026137275 0.9439851252535618 1.0 1.0 60 Q8TAA9,P08236,O15460,Q9NQX3,P16278,O00754,P31749,Q15056,P51648,P54802,P01889,P15586,O75844,Q15427,O43709 15 +Abnormality of blood circulation 0.3676475664628568 0.07012686970504 0.944092680412254 1.0 1.0 71 Q13277,Q9BZK7,Q04656,P04062,P05067,Q14739,P60866,Q9NZ08,P21359,P01889,Q9Y487,Q9Y4U1,O60333,P10644,P31749,P40763,P29992,O75844,Q99643 19 +Abnormality of the periorbital region 0.3654046679374237 0.069388294190445 0.9446805463444212 1.0 1.0 72 P56589,Q96N67,P98164,Q8IWS0,Q9P2R3,P28070,Q9Y5K6,Q9Y4P3,Q93074,Q8NFV4,Q7LGA3,P40855,O75381,Q9ULC3,O43709,Q99519,P52565,O43707,Q15056 19 +Overlapping fingers 0.3323615653206235 0.068997082630761 0.9449919416904468 1.0 1.0 9 Q8TD19,Q15125,Q8TD16 3 +Central hypoventilation 0.3251512840536218 0.068185728359579 0.94563778764885 1.0 1.0 7 Q8N183 1 +Nyctalopia 0.3850172068487407 0.0681254398334045 0.945685779338421 1.0 1.0 33 Q15555,Q10713,P56589,O43395,O43172,P50213,P40855,Q9H9E3,Q9Y287,O75381 10 +Round face 0.3647138325188321 0.0674514945213551 0.9462222757956726 1.0 1.0 21 Q32P28,Q8WVQ1,P31749,P10644 4 +Profound global developmental delay 0.3491325837881743 0.065705835902752 0.9476120260778936 1.0 1.0 15 Q9H490,P56589,O60313,Q9H3S7,P40855,O75381 6 +Congenital hepatic fibrosis 0.3200591669860536 0.0651253669795071 0.948074183372736 1.0 1.0 6 Q10713,Q8NCM8 2 +Abnormality of adrenal physiology 0.3849313187695669 0.0642335302956123 0.9487842791971048 1.0 1.0 34 Q9Y697,P10644,P31749,Q13423,P38571 5 +Multiple cafe au lait spots 0.3484110520774913 0.0639796550778513 0.9489864265082508 1.0 1.0 15 P31749 1 +Abnormality of vitamin b metabolism 0.3534916490930342 0.0632683118380216 0.9495528486821668 1.0 1.0 17 Q9Y4U1,O43567 2 +Large basal ganglia 0.3478817293897348 0.0627204086924154 0.949989145601807 1.0 1.0 15 P49591,Q9UBB6,Q96N66 3 +Serositis 0.3604714991588554 0.0622427262274567 0.9503695378214037 1.0 1.0 20 Q9Y5K6,P52565,O15460,O43707,P01889,Q9P2R3,Q9NZ08 7 +Jaundice 0.3837039824975863 0.0621326627524203 0.9504571861232858 1.0 1.0 60 P00374,Q15904,P56589,P35670,O15118,Q04656,Q9Y4U1,P40855,P10644,P11413,P61916,O75787,Q8NB49,P38571 14 +Cystic hygroma 0.3184638109305796 0.0619711341718713 0.9505858193979232 1.0 1.0 6 Q99567,P61978,Q96S52,Q14739,Q06124 5 +Abnormal vena cava morphology 0.3289399173666207 0.061705949472286 0.9507970020069004 1.0 1.0 9 Q8ND04 1 +Tetraparesis 0.3860445729402776 0.0613140871151147 0.9511090720152178 1.0 1.0 36 P17900,P07602,Q9UBX3 3 +Small earlobe 0.3217187812766328 0.0612031256101995 0.9511974405245596 1.0 1.0 7 P10586 1 +Abnormality of facial musculature 0.3381900293262783 0.0593061090389703 0.9527082953722056 1.0 1.0 82 P56589,O60313,P04062,O75787,Q9BUF5,Q93074,P10253,Q13555,Q9Y263,Q7LG56,Q13510,P40855,Q14203,Q9BQP7,Q9NQ11,Q96RR1,P54098,O00754,P31749,P51798,P35270,Q9H9S5 22 +Sparse scalp hair 0.3822037702234218 0.05912281173593 0.9528542892825944 1.0 1.0 33 P08069,Q14574,P48449 3 +Abnormal right ventricle morphology 0.3204082664216616 0.058601098235253 0.9532698359229336 1.0 1.0 7 P19022 1 +Sensory neuropathy 0.386465786538141 0.0570555463452678 0.954500947580236 1.0 1.0 38 Q8IV08,Q9NQ11,Q96RR1,P54098,Q15041,P00403,P51797,O95831,Q13472,P07384 10 +Urethral obstruction 0.3601732210411574 0.0555141518961806 0.9557288557537904 1.0 1.0 21 P23229,Q9BUR4,Q9Y4P3,Q15056,Q9NX24,O43709 6 +Nevus 0.3768073530055493 0.05482045769105 0.9562815020281898 1.0 1.0 30 Q9UHX1,Q8TD19,Q9Y4P3,P10644,P31749,Q15056,Q8NFV4,O43709,Q99643 9 +Hypoparathyroidism 0.3378711624876679 0.0532133886728344 0.9575618881119404 1.0 1.0 13 P35670,O00192,P00403 3 +Vaginal neoplasm 0.3055801594331345 0.0530247125304027 0.9577122176556364 1.0 1.0 4 O43684,O60566,Q15645 3 +Shoulder dislocation 0.300177095631646 0.0511324641722389 0.9592199671506608 1.0 1.0 3 P21333,P46821 2 +Pointed chin 0.3815393031500834 0.0498486790829096 0.9602429745759546 1.0 1.0 35 Q7LGA3,Q9H490,O43709,Q9Y4P3,P19022,P11233,Q15056,Q7LBC6,Q96EK5,Q9UQR1 10 +Paroxysmal ventricular tachycardia 0.2992916174734423 0.0496434490121151 0.9604065219923053 1.0 1.0 3 P14923,P04899 2 +Abnormality of the ankles 0.3873055600068905 0.0489051727233822 0.9609948665597716 1.0 1.0 44 P07602,Q93063,O00754,Q15056,O75787,O43709,P07384,Q969X5 8 +Protrusio acetabuli 0.2987012987013053 0.0486593955638843 0.9611907351661716 1.0 1.0 3 O75718,Q02809 2 +Abnormality of exocrine pancreas physiology 0.352415599594601 0.0481261138485536 0.961615734472732 1.0 1.0 19 Q15904 1 +Hammertoe 0.3568219860771289 0.0469976349114636 0.9625151125147736 1.0 1.0 21 Q9UBM7,Q99720 2 +Knee flexion contracture 0.369161245538707 0.0468801717949437 0.9626087313316992 1.0 1.0 27 Q7LGA3 1 +Clitoral hypoplasia 0.3060997504570801 0.046541636289258 0.9628785490642482 1.0 1.0 5 Q9NP72,Q9H2M9 2 +Hypoplastic labia minora 0.3060997504570801 0.046541636289258 0.9628785490642482 1.0 1.0 5 Q9NP72,Q9H2M9 2 +Open mouth 0.3789992657507527 0.0453609544618257 0.9638196027587502 1.0 1.0 34 Q93074,P04062,P10644,P31749,Q96PZ0 5 +Decreased circulating antibody level 0.3859459504249989 0.0429947370097057 0.9657057292337774 1.0 1.0 45 O43909,O00754,O60934,P40763,Q15904,P02786 6 +Respiratory failure 0.3716291606239371 0.0425223780409013 0.9660822727850624 1.0 1.0 66 Q9BQP7,Q8TD16,P07602,Q5XKP0,Q9Y697,O43464,Q13510,P61916,O60934,Q70HW3,Q8N183,P10253,Q14203 13 +Exercise intolerance 0.3817912836869929 0.041438552534563 0.9669462787008812 1.0 1.0 38 Q9BQP7,P13473,Q96RR1,P54098,P00403,P46020,Q13472,Q07021 8 +Neoplasm of the liver 0.3828742616038812 0.0400220875716456 0.9680755170627452 1.0 1.0 40 P35670,P11717,Q9UDY2 3 +Eclabion 0.3800188602490926 0.0385738052270478 0.9692301871450184 1.0 1.0 37 Q69YQ0,Q9BZK7,Q9Y4P3,Q96N67,P04062,Q9H9B1,Q15056,Q8NFV4,Q9H2M9,P08069,Q96EK5,O43709,Q96PZ0 13 +Lower limb hyperreflexia 0.3478113174239489 0.0372100566329463 0.9703175201331096 1.0 1.0 19 Q15041,Q9NQ11 2 +Neonatal death 0.3299033512757727 0.0364048505354308 0.9709595465768486 1.0 1.0 13 P04062,O96000 2 +Frequent falls 0.3824141830693043 0.03631177370158 0.9710337620755742 1.0 1.0 41 P07602,Q96RR1,P54098,P04062,Q13510,Q9NQX3,O75787 7 +Long fingers 0.3347708960292689 0.0362839377203361 0.9710559573489084 1.0 1.0 82 Q93074,Q8N6M0,Q9H9B1,P42892,O43567,Q14671,P53634,O96028,Q96EK5,Q15125,Q8NCH0 11 +Blepharophimosis 0.3836886287766212 0.0360791368761435 0.9712192578566096 1.0 1.0 52 Q7LGA3,Q15555,Q8N3R9,Q9BZK7,Q9Y4P3,Q93074,Q92917,Q9BXW9,Q9H3S7,Q13620,P61586,Q8IWS0,Q15056,Q8NFV4,Q6W2J9,O75844,O43709,Q96PZ0 18 +Premature graying of hair 0.3157639125779727 0.0358980645801746 0.9713636391156588 1.0 1.0 9 Q13126,Q9NX24 2 +Optic atrophy 0.2624873044653512 0.0358290215081237 0.971418692101079 1.0 1.0 204 P07602,P56589,Q7KZN9,O60313,O15460,P16278,Q9H173,O00192,Q5KU26,Q9H490,P06280,O43395,P61586,P01889,P50897,Q8N183,Q8NC96,Q9UBM7,Q15555,O43292,Q13144,Q9Y263,Q5XKP0,Q9Y4U1,P40855,P00403,O43505,O96028,Q9ULC3,Q15125,P41440,Q99519,Q9BV79,Q96RR1,P54098,P10644,P51798,Q9GZZ9,P29992,Q9H9S5 40 +Vertebral segmentation defect 0.3754579750001744 0.0345029105195254 0.9724761214727172 1.0 1.0 34 Q9UHX1,Q8TAA9,Q9Y4P3,Q15125,Q9H9S5,Q15056,O96028,O43709,P63241 9 +Abnormal cerebellar vermis morphology 0.3315070085377543 0.0341192919573104 0.9727820246833336 1.0 1.0 83 Q69YQ0,Q10713,Q15334,Q9H173,Q6W2J9,P42356,Q9H490,Q9C0B1,Q13620,Q9H2M9,Q14671,Q9UBM7,Q9Y487,P15291,Q7Z3E5,O43505,Q15125,Q8NCM8,P43034,P22570,Q9UN37,Q9H9S5 22 +Occipital meningocele 0.2986093784476169 0.0340547513447375 0.9728334907331082 1.0 1.0 5 Q10713 1 +Abnormality of the scrotum 0.3822419150891017 0.0337182088212845 0.973101858688524 1.0 1.0 54 Q7LGA3,Q15555,Q9UBM7,Q69YQ0,Q9H0U9,Q93074,Q9H3S7,P31749,Q8IWS0,Q96EK5,Q96PZ0 11 +Flared metaphysis 0.3067950949190025 0.033648101689718 0.9731577643633648 1.0 1.0 7 Q14807,Q9H9E3,Q14739,Q96HY6 4 +Abnormality of renal excretion 0.3067524069897605 0.033575765457758 0.9732154477325732 1.0 1.0 7 Q9UNF1 1 +X linked recessive inheritance 0.3814054389606404 0.0325512534474206 0.9740324433221832 1.0 1.0 55 Q15904,P06280,Q93074,Q04656,Q9UNF1,Q8IWS0,O95831,O75787,P46020,Q8NB49,P11413,Q15125 12 +Esophageal neoplasm 0.305851063829807 0.0320569497890932 0.9744266348415692 1.0 1.0 7 P31040,Q6PD74,P42224,O60216,P21912,Q99643 6 +Hypoketotic hypoglycemia 0.3089717511080126 0.0306244574843869 0.9755690370431382 1.0 1.0 8 P31751,O43772 2 +Low levels of vitamin d 0.3087246679155642 0.0302023321760348 0.9759056885738338 1.0 1.0 8 Q7Z2Z2,P46783,Q10471 3 +T lymphocytopenia 0.3122325184899989 0.0295892526150256 0.9763946367328608 1.0 1.0 9 O43909 1 +Generalized myoclonic seizure 0.3818710455393002 0.0294144837584912 0.976534021434371 1.0 1.0 44 Q99519,P07602,Q01105,P04062,Q13510,Q96N66,P16278 7 +Abnormal atrioventricular valve morphology 0.3786829566020625 0.0286197048471847 0.9771678963253784 1.0 1.0 39 P21359,O43909,Q9Y4P3,P04062,Q93074,Q9UBS4,P54098,Q15056,Q6W2J9,O00192,O75844,O43709 12 +Abnormal dental pulp morphology 0.3149732124130814 0.0277965775635507 0.977824395618085 1.0 1.0 10 P21359,Q9NX24 2 +Small face 0.3813512361774865 0.0275917116309222 0.9779877923106371 1.0 1.0 44 Q7LGA3,Q8N3R9,Q9Y4P3,Q93074,Q04656,Q9H3S7,Q96ST3,Q15056,P26196,Q8NFV4,Q6W2J9,O43709,Q96PZ0 13 +Impaired smooth pursuit 0.3317533179925092 0.027240311734262 0.978268063510414 1.0 1.0 15 P41440,O00754,Q10713 3 +Type i diabetes mellitus 0.317183168933517 0.0251861351751244 0.9799064959768592 1.0 1.0 11 Q5JRA6,P40763 2 +Prominent nasal bridge 0.3788952329651648 0.0246179625767267 0.980359691577088 1.0 1.0 56 Q69YQ0,Q10713,Q93074,Q96N67,Q93063,Q8N6M0,Q96ST3,P42892,O60934,Q10471,Q15427,Q7Z3E5,Q5JRA6,Q96EK5,Q15125 15 +Open bite 0.3389854681585518 0.0236236762545794 0.9811527864994888 1.0 1.0 18 Q9Y4P3,P10644,Q13620,Q15056,O43709 5 +Bilateral polymicrogyria 0.3125582102503293 0.0235552131262862 0.9812073969760888 1.0 1.0 10 P39880,P42356,Q01105 3 +Disinhibition 0.3802004022313658 0.0235412757454506 0.981218514314256 1.0 1.0 53 P49591,P17480,P15311,Q8TAA9,Q9UBB6,P19022,P04062,P05067,O43464,Q96N66,Q9GZZ9,Q9NUM4,Q14203 13 +Nonimmune hydrops fetalis 0.3640500515591343 0.023247955969836 0.9814524855978136 1.0 1.0 29 P10619,P62857,P04062,O96000,Q14739 5 +Conical tooth 0.3075592174066523 0.0216308429404612 0.9827424301748876 1.0 1.0 9 Q9Y487,P61586 2 +Episodic hyperhidrosis 0.3179739785711399 0.0201249634317288 0.9839436862374702 1.0 1.0 12 P21359,O60333 2 +Shuffling gait 0.3138637863628193 0.0193171675133766 0.9845880887886445 1.0 1.0 11 P54098,P04062,Q14203 3 +Thick nasal alae 0.3309333387185971 0.0193142169072673 0.9845904425925658 1.0 1.0 16 P21359,P31749 2 +Abnormal fallopian tube morphology 0.3018031333136237 0.0188755283532779 0.9849404016081668 1.0 1.0 8 Q92878,P38398,Q2M1P5,O60934,P49959,P04637,O96017 7 +Thoracic hypoplasia 0.3686751911066993 0.0185037071895418 0.9852370201631596 1.0 1.0 33 Q9UHX1,Q8TD19,Q8WVQ1,Q96HY6,Q8NCM8,Q04656,P04062,P51798,P41227,Q14739,Q6W2J9 11 +Visual field defect 0.379586511673913 0.0184973254582101 0.9852421111767375 1.0 1.0 47 Q15555,P56589,O43395,O60313,O15460,P40855,P31749,P00403,P01889,Q9Y287,P04439 11 +Abnormal thoracic spine morphology 0.3620034658541043 0.0178215498345896 0.9857812132072684 1.0 1.0 29 O43909,P08236,P04062,O00754,P51648,O75844,O95831 7 +Slowly progressive 0.3730067898427506 0.0176044986246655 0.9859543678503592 1.0 1.0 61 P41440,Q8IV08,Q04446,Q04656,O60333,O95831,O14773,O75787,O00584,Q6UWE0,Q99720,Q14203 12 +Neoplasm of the respiratory system 0.3299467030196223 0.0173597934600831 0.9861495844887772 1.0 1.0 16 Q9UPY3,P31749 2 +Abnormal dermatoglyphics 0.3495573370371803 0.0162173510179202 0.9870609931733012 1.0 1.0 75 Q69YQ0,Q9BZK7,P56589,Q9H9B1,Q96ST3,Q6W2J9,Q969X5,O43909,Q9Y4P3,Q93074,Q92917,Q8NFV4,Q9H2M9,Q8NCH0,Q9UBM7,Q9Y487,Q9Y263,P40855,P41227,O96028,O43709,Q9UHX1,Q15056 23 +Multiple renal cysts 0.3291412748425075 0.0157798651652258 0.9874100117084944 1.0 1.0 16 Q9Y4P3,O43709,Q15056,O00192 4 +Cytochrome c oxidase negative muscle fibers 0.2992233691563256 0.0148976045751638 0.9881138709833396 1.0 1.0 8 Q96RR1,P54098 2 +Abnormality of the calcaneus 0.2990710251637246 0.0146667900544136 0.9882980142054704 1.0 1.0 8 O75787 1 +Abnormal male reproductive system physiology 0.3686640672949695 0.0145407780442097 0.9883985465219608 1.0 1.0 34 Q9Y4P3,P04062,Q9BXW9,Q9UBS4,O43464,Q9H1A4,Q13423,P07686,P31749,Q15056,O43709 11 +Decreased testicular size 0.3400153164774003 0.0138810671326437 0.98892486651542 1.0 1.0 20 Q8IWS0,O43505 2 +Semilobar holoprosencephaly 0.2793032181871944 0.0134256902613592 0.9892881708230068 1.0 1.0 4 Q14683,Q8N3U4,O94979 3 +Solitary median maxillary central incisor 0.2793032181871925 0.0134256902613567 0.9892881708230088 1.0 1.0 4 Q14683,Q8N3U4,Q6W2J9 3 +Dermatological manifestations of systemic disorders 0.3467176903846207 0.013037013203812 0.9895982630995012 1.0 1.0 76 P00374,P04066,Q15904,P56589,P35670,O15118,Q04656,Q9Y4U1,P40855,P10644,P11413,P61916,O75844,O75787,Q8NB49,P38571 16 +Wide cranial sutures 0.2975469739848504 0.0123827292408248 0.9901202639987084 1.0 1.0 8 Q93074 1 +External ophthalmoplegia 0.339133951705171 0.0120070053395398 0.9904200260065548 1.0 1.0 20 Q9BQP7,Q96RR1,O60313,P54098,P00403,Q13472,Q8N183,Q07021 8 +Hypertriglyceridemia 0.3515375203894018 0.0118203518113944 0.9905689434059396 1.0 1.0 25 P38571,P28070 2 +Agenesis of incisor 0.2775963736671022 0.0113056462253389 0.9909795915885262 1.0 1.0 4 Q6W2J9 1 +Benign neoplasm of the central nervous system 0.3458373090256049 0.0095254673053266 0.9923998916348612 1.0 1.0 23 P21359,O60333,P31749,Q99643 4 +Nasal speech 0.3713786677745149 0.008650071577935 0.9930983275063894 1.0 1.0 38 Q7LGA3,Q9BQP7,Q4J6C6,Q9Y487,Q93074,Q9H3S7,O00192,Q96PZ0 8 +Abnormal proportion of cd4 positive t cells 0.2946290202228419 0.0081357872502871 0.993508652574598 1.0 1.0 8 O43909 1 +Broad long bones 0.3709499952367965 0.0073603334841571 0.9941273565752742 1.0 1.0 38 Q7LGA3,Q8N3R9,O43909,Q93074,Q9H3S7,Q8N6M0,Q9ULC3,Q96PZ0 8 +Arrhinencephaly 0.3066055308208995 0.0072691019874809 0.994200146830555 1.0 1.0 11 Q15427,Q8TAA9 2 +Muscular dystrophy 0.3534703685321333 0.0060967709032224 0.9951355107615952 1.0 1.0 27 O43505 1 +Echolalia 0.3052253974149961 0.0050987607216855 0.9959317951680448 1.0 1.0 11 Q9NUM4,O75787,Q9H9B1 3 +Biconcave vertebral bodies 0.2764323685764994 0.0034410798995506 0.997254420894075 1.0 1.0 5 Q14807,P40818,Q96AY3,Q9NR45 4 +Macrodontia 0.3375189016101658 0.0028476339871364 0.9977279198775704 1.0 1.0 21 Q7LGA3 1 +Abnormality of the ulna 0.3682381822742607 0.0025473592463566 0.997967503584672 1.0 1.0 37 Q8WVQ1,Q8NCM8,Q9Y4P3,Q93063,Q9BXW9,P10644,Q9H1A4,Q15056,Q8NFV4,Q6W2J9,O96028,Q15427,O43709 13 +Diffuse white matter abnormalities 0.2992693600830955 0.0023266509659182 0.9981436027907908 1.0 1.0 10 P16278 1 +Abnormality of hindbrain morphology 0.258932360142778 0.0017948660867533 0.9985679048295972 1.0 1.0 289 Q69YQ0,Q10713,Q8TD16,Q9BZK7,Q96N67,Q9H9B1,O75503,O14773,O75787,Q9H173,Q9H490,Q9C0B1,Q93074,Q92917,Q14108,Q9NQX3,Q13472,Q14671,Q9UBM7,O43292,Q8IV08,Q8TAA9,Q9Y487,Q5XKP0,P15291,O43567,Q7Z3E5,O43505,O96028,O43709,Q99720,Q15125,P00374,P41440,Q9BQP7,Q9NQ11,Q96RR1,P54098,O00754,P31749,P51798,Q15056,Q9GZZ9,Q9UN37,Q9H9S5,Q99643 46 +Abnormal pulmonary valve morphology 0.3145038782278451 0.0015331568476149 0.9987767183012336 1.0 1.0 14 P51798,P10644 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..391be0e2f9ff90c818229237901d19c93ba516f7 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal energy expenditure", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pulse", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 2nd finger", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal interphalangeal creases", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent phalangeal crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanges of the toes", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hallux", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalomalacia", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged interphalangeal joints", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid apraxia", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemolytic uremic syndrome", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low serum calcitriol", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple epiphyseal dysplasia", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neonatal short limb short stature", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic calcification", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent spontaneous abortion", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short middle phalanx of the 2nd finger", "Short middle phalanx of toe", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Stapes ankylosis", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth abscess", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCD3", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG12", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOB", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARV1", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATP11C", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5D", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "ATXN10", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDK", "BCOR", "BCS1L", "BICD2", "BLVRA", "BMS1", "BOLA3", "BPTF", "BRCA1", "BRD4", "BTRC", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CASK", "CBFB", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CD3EAP", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDKN2A", "CELF2", "CEP135", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK2", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "CNP", "COA7", "COASY", "COG4", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CUX1", "CWF19L1", "CYB5R3", "CYC1", "DARS", "DARS2", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DTNA", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "ENPP1", "EPB41", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAH", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOXD13", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPD1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IQCB1", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF4A", "KIF5C", "KIF7", "KIFBP", "KMT2A", "L2HGDH", "LAMB1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRSAM1", "LSS", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MANBA", "MAP1B", "MAP2K1", "MAP2K2", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCC", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED12", "MED13", "MED17", "MED23", "MESD", "MFN2", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMACHC", "MMADHC", "MOCS1", "MOCS2", "MOGS", "MORC2", "MPG", "MPI", "MPP5", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEU1", "NF1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUS1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OTUD6B", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRICH1", "QRSL1", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAI1", "RALA", "RALGAPA1", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP6", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "RNF13", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RRM2B", "RTN2", "RTN4IP1", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STARD7", "STAT1", "STAT3", "STT3A", "STT3B", "STUB1", "STX3", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM50", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM106B", "TMEM126A", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM63A", "TMEM70", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53RK", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXN2", "TXNL4A", "UBA1", "UBA5", "UBE4A", "UBE4B", "UBTF", "UFC1", "UFD1", "UFM1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VPS13A", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR34", "WDR36", "WNK1", "WRAP53", "XIAP", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YME1L1", "YWHAE", "YWHAG", "YY1", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF148", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["AAGAB", "AASS", "ABCB1", "ABHD11", "ACAT2", "ACP2", "ACTN1", "ACTN4", "ADK", "AIFM1", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ANAPC1", "ANKFY1", "AP3B1", "APOB", "APOL2", "APP", "APRT", "ARHGDIA", "ARL3", "ARL6IP1", "ARMC9", "ARVCF", "ASAH1", "ATP11C", "ATP13A2", "ATP2B4", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "ATP7A", "ATP7B", "ATRX", "B4GALT1", "B4GAT1", "BCOR", "BICD2", "BLVRA", "BRCA1", "BTRC", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAMK2G", "CANT1", "CAPN1", "CCT5", "CD2AP", "CDC42", "CDH2", "CDKN2A", "CEP290", "CHEK2", "CHST14", "CHUK", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLN6", "COG4", "COG6", "COG8", "COLEC12", "COPA", "COPB2", "COX15", "COX2", "CPNE1", "CPOX", "CPT1A", "CRTAP", "CTNNB1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL4B", "CUX1", "DCTN1", "DDOST", "DDRGK1", "DDX6", "DEGS1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX38", "DICER1", "DKC1", "DNAJB11", "DNM2", "DNMT1", "DOCK7", "DSC3", "DSG2", "DSP", "DTNA", "DYNC2H1", "EARS2", "EBP", "ECE1", "EFL1", "EHMT1", "EIF2B3", "EIF2B5", "EIF3F", "EIF4H", "EIF5A", "ELP2", "EMC1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "EXOC2", "EXOC7", "EXT2", "EXTL3", "EZR", "FANCD2", "FASN", "FDXR", "FKBP10", "FKRP", "FLNA", "FLNB", "FMR1", "FTO", "FUCA1", "G6PD", "GAA", "GALNS", "GALNT2", "GARS", "GATAD2B", "GBA", "GBE1", "GEMIN5", "GLA", "GLB1", "GLRX5", "GLUD1", "GM2A", "GMPPA", "GNA11", "GNAI2", "GNAI3", "GNS", "GPAA1", "GPHN", "GPKOW", "GSR", "GUSB", "HEXA", "HEXB", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB3", "HNRNPDL", "HNRNPK", "HPS6", "HS2ST1", "HTRA2", "HUWE1", "IARS2", "IDH3A", "IGBP1", "IGF1R", "IGF2R", "IMPAD1", "IMPDH1", "IRS4", "ITGA6", "ITM2B", "JUP", "KDM3B", "KIAA0319L", "KIF11", "KIF1B", "KIF22", "KIF7", "KIFBP", "LAMP2", "LARS2", "LBR", "LEMD2", "LIPA", "LLGL1", "LRBA", "LRP1", "LRP2", "LRSAM1", "LSS", "MAGED2", "MAGT1", "MAN2B1", "MANBA", "MAP1B", "MAPRE2", "MAT2A", "MBOAT7", "MCM10", "MCM4", "MCM7", "MECR", "MED12", "MED17", "MFN2", "MGME1", "MIA3", "MID1", "MIPEP", "MMACHC", "MOCS2", "MPG", "MPP5", "MRE11", "MRPS16", "MSH2", "MSH6", "MTAP", "MYH14", "NAA10", "NAGLU", "NANS", "NBN", "NCAPD3", "NCDN", "NCSTN", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB9", "NDUFS3", "NECAP1", "NEFL", "NEK9", "NEU1", "NF1", "NFS1", "NHLRC2", "NHP2", "NNT", "NONO", "NPC1", "NPC2", "NSD2", "NSMCE2", "NSUN2", "NUP188", "NUP88", "NXN", "OGDH", "OPA1", "OTUD6B", "P3H1", "P4HA2", "PAFAH1B1", "PARN", "PCBD1", "PEX14", "PEX19", "PEX3", "PFKM", "PHF6", "PHIP", "PHKA1", "PI4KA", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3R2", "PLAA", "PLD3", "PLOD1", "PMPCA", "POLA1", "POLD1", "POLE", "POLG", "POR", "PPA2", "PPIL1", "PPT1", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRPF3", "PRPF31", "PRPF4", "PSAP", "PSMB4", "PSMG2", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUS1", "PUS7", "PXMP2", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAC1", "RAD21", "RAD50", "RALA", "RBM10", "RBM28", "RDH11", "RDX", "RHOA", "RNASET2", "RNF13", "RPL10", "RPL11", "RPL15", "RPS10", "RPS20", "RPS23", "RPS28", "RRM2B", "RTN2", "SALL2", "SAR1B", "SARS", "SCARB2", "SDHA", "SDHB", "SDHC", "SEC31A", "SEC63", "SERPINB6", "SET", "SF3B1", "SF3B4", "SFXN4", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A24", "SLC25A26", "SMC1A", "SMCHD1", "SMG8", "SMS", "SNRNP200", "SPECC1L", "SPR", "SPTLC1", "SPTLC2", "SRP54", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STX3", "SUCLG1", "TBL1XR1", "TBL2", "TCOF1", "TFG", "TFRC", "TJP2", "TMEM106B", "TMEM165", "TMEM63A", "TNPO3", "TOP3A", "TOR1A", "TP53", "TPM1", "TPM3", "TPP1", "TRAPPC11", "TRIM32", "TRIP13", "TRRAP", "TSPYL1", "TTC37", "TUBB2A", "TUBB6", "TUBG1", "TWNK", "UBA5", "UBTF", "UMPS", "UPF3B", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "VANGL1", "VARS1", "VCP", "VPS4A", "WNK1", "WRAP53", "YARS", "YARS2", "YWHAE", "ZMPSTE24", "ZNF148"]} \ No newline at end of file diff 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0000000000000000000000000000000000000000..1056ee1874a7e2aa085dfdd73b8d53a3d85daf19 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 36 54 3.0232380258642424 0.0025008545394471 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 1.055864324437061e-28 3.646145743695136e-19 1.812413408451589e-36 7.327458555758339e-35 2.378865061257813e-28 +Other glycan degradation 8 9 2.8000514931784006 0.0051094455360993 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 3.150454928270948e-06 3.8887516945815136e-05 1.3836932757398312e-07 4.646107203398658e-12 2.246895762258043e-09 +Glycosaminoglycan degradation 6 7 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4.854368932038835 0.2295754227924032 0.537404328385132 1.0159064595639915 0.605921700063298 0.9114211067852314 0.3048453574503886 1.0 1.0 1.0 0.005208827916976 0.0334620993119388 +Jak stat signaling pathway 3 8 2.0107193892204904 0.04435510484242 2.5388349514563107 7.325242718446602 0.1247408981464117 0.5305016303730072 1.7532069372986143 1.6446570419841182 0.9424863908946578 0.315817052482574 1.0 1.0 1.0 0.1214587331941242 0.2236139420972091 +Hedgehog signaling pathway 2 5 2.009955520401585 0.0444358967213038 1.4393203883495145 3.504854368932039 0.0561028783324411 0.6136783235425893 1.060640731552855 1.080487002817531 0.8868963519468946 0.3125197143580914 0.1896456305212858 0.1244478155008913 0.2297987482657219 0.4860897569734319 0.3798345415961738 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bcd8742e5ed853042c3638f0e61689cd7f0fa28e --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 17.569060773480665 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7af1b62671cf5c4cc4ffe0c34fe97bb8f7508837 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..52c80767c0252931eadbb13ebce7f01d8ab2d2d8 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,77 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.8848058568303704 3.0232380258642424 0.0025008545394471 0.3644227442304369 0.1187063340858603 54 P07858,Q99523,P07602,P34059,O15118,P17900,P04062,P16278,O75503,O14773,Q9UMR5,P38571,P11717,P04066,P06280,Q99538,P06865,P08236,P11117,Q14108,P54802,P50897,P15586,P53634,Q15904,P10253,P10619,P13473,P11279,Q13510,P07686,P61916,Q8NCC3,O00462,Q99519,O00754 36 +Glycosphingolipid biosynthesis globo series 0.9775678866587948 2.8789939317824302 0.0039894601038601 0.5149661032868831 0.1187063340858603 3 P06865,P06280 2 +Glycosphingolipid biosynthesis ganglio series 0.958677685950411 2.8013382169944374 0.005089115124502 0.602866065244162 0.1187063340858603 3 P06865,P07686 2 +Other glycan degradation 0.9603784742755735 2.8000514931784006 0.0051094455360993 0.604332217565914 0.1187063340858603 9 O00462,Q99519,P04066,P06865,P04062,O00754,P07686,Q9BTY2 8 +Glycosaminoglycan degradation 0.9515366430260098 2.7630934711534736 0.0057256367251683 0.646304347646997 0.1187063340858603 7 P34059,P06865,P16278,P07686,P54802,P15586 6 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.9403778040141644 2.7254162538579445 0.0064220465982927 0.6884324014346839 0.1187063340858603 3 Q9NRB3,Q8NCH0 2 +Glycosaminoglycan biosynthesis keratan sulfate 0.9391971664698912 2.7204944544188128 0.0065184365223269 0.693855831601818 0.1187063340858603 3 O43505,O60512 2 +Glycosphingolipid biosynthesis lacto and neolacto series 0.9394744611750858 2.7184750084903393 0.0065583609992188 0.6960746112175002 0.1187063340858603 4 O43505,Q11206,O60512 3 +O glycan biosynthesis 0.9288455860643656 2.673850694462045 0.0074985827944396 0.7439436572232347 0.1219810403967265 4 Q86SF2,Q10472,O43505 3 +Glycosaminoglycan biosynthesis heparan sulfate 0.912927981109794 2.610237931727552 0.0090479267858654 0.807012242306082 0.1219810403967265 3 Q7LGA3,Q93063 2 +Hematopoietic cell lineage 0.9055768663322408 2.5833686546300725 0.0097840713592118 0.8313006650262424 0.1219810403967265 2 P02786 1 +Graft versus host disease 0.8900128383573586 2.508807869334919 0.0121139353530037 0.8898609013845582 0.1219810403967265 4 P10321,P01889 2 +Allograft rejection 0.8900128383573586 2.508807869334919 0.0121139353530037 0.8898609013845582 0.1219810403967265 4 P10321,P01889 2 +Autoimmune thyroid disease 0.8900128383573586 2.508807869334919 0.0121139353530037 0.8898609013845582 0.1219810403967265 4 P10321,P01889 2 +Renin angiotensin system 0.8898989018344166 2.508318960198733 0.0121307111996744 0.8901989149243248 0.1219810403967265 4 Q9UIQ6,P10619 2 +Ecm receptor interaction 0.8768699477235389 2.444744753743661 0.0144954689035292 0.9288440540768031 0.1311839935769398 6 Q08722,P23229,Q7L0J3,P06756 4 +Cell adhesion molecules cams 0.8017867604367039 2.094123841343201 0.0362489497713431 0.9987478958860472 0.3005855743078011 13 P23229,Q9BY67,P10321,P05556,P06756,P19022,Q92859,P01889,Q92896,Q9Y624,P04439 11 +Type i diabetes mellitus 0.7923873197557405 2.074269248419521 0.0380543121084202 0.9991082359871852 0.3005855743078011 5 P10321,P01889 2 +Folate biosynthesis 0.7869224478894776 2.0552314921300505 0.039856650736946 0.9993649175448563 0.3005855743078011 4 P00374,Q92820 2 +Jak stat signaling pathway 0.7813139215590286 2.0107193892204904 0.04435510484242 0.9997285595870546 0.3093422040983078 8 P40763,P31751,P31749 3 +Hedgehog signaling pathway 0.7781893922554538 2.009955520401585 0.0444358967213038 0.9997326817381152 0.3093422040983078 5 P98164,Q9ULC3 2 +Small cell lung cancer 0.764751404430694 1.922088184733978 0.0545946625166802 0.9999613751303136 0.3518169279708578 12 P23229,P05556,P31751,P06756,P31749 5 +Sulfur metabolism 0.753075514662633 1.908176111456558 0.0563684580726788 0.9999725056592677 0.3518169279708578 3 Q9NRB3 1 +Galactose metabolism 0.7571785976114276 1.8825993252749775 0.0597546878977801 0.9999856565706732 0.3582629701774326 14 P10253,P16278,P06280 3 +Antigen processing and presentation 0.7550221677818097 1.870892691608278 0.0613599562182343 0.9999894723096237 0.3582629701774326 19 Q99538,P10321,P07858,P01889 4 +Sphingolipid metabolism 0.7275128640613417 1.7401795671489273 0.0818274923029129 0.99999980533156 0.4262851238344159 14 Q99519,P06280,P04062,Q13510,P16278 5 +Basal transcription factors 0.6823485219700534 1.5659183642820742 0.1173677300161633 0.9999999998464874 0.4940362589052455 5 Q00403 1 +Toll like receptor signaling pathway 0.6671153783696523 1.4493485028852622 0.1472402822695397 0.9999999999996982 0.5793585019736239 13 P31751,Q16539,P31749 3 +Starch and sucrose metabolism 0.6551509244601625 1.377613553065666 0.1683226342165276 0.9999999999999968 0.621763199861051 17 Q8NBZ7,P10253 2 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6378820000369549 1.3552952564157466 0.1753235057374456 0.9999999999999992 0.62748716842105 5 Q9H490 1 +Dilated cardiomyopathy 0.6220833909218809 1.2445440239180272 0.2132994072523049 1.0 0.6603822140629754 10 P06756,P23229,P05556,P09493 4 +Melanoma 0.6225781279390752 1.2306673972594224 0.2184472866117794 1.0 0.6603822140629754 13 P31751,P31749 2 +Acute myeloid leukemia 0.6166917856303002 1.2017096715210906 0.2294760326864147 1.0 0.6603822140629754 13 P40763,P31751,P31749 3 +Viral myocarditis 0.6115626614659673 1.1817454904274494 0.2373067023718906 1.0 0.6608078942971108 12 P10321,P01889,P78310 3 +B cell receptor signaling pathway 0.602366643161157 1.1367240104238845 0.2556536787138179 1.0 0.6824116108716217 12 P31751,P31749 2 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.5968695086956988 1.0990752617912296 0.2717352392924326 1.0 0.6985677138182718 14 P23229,P05556,P06756,P19022,O43707,P15924,P12814,Q14126 8 +Leishmania infection 0.5865432548314071 1.09384309596432 0.2740237993430789 1.0 0.6985677138182718 7 Q16539 1 +Pancreatic cancer 0.5913080569507012 1.058075074166971 0.290021217160977 1.0 0.7233918565129381 17 O15111,P60953,P31751,P11234,P31749,P11233,P40763 7 +Prostate cancer 0.5874916313418066 1.0351969511701933 0.3005769423362547 1.0 0.7233918565129381 18 P08069,P31751,P31749 3 +Fc epsilon ri signaling pathway 0.5616986219017093 0.9385776482287286 0.3479476331795827 1.0 0.7747201566674743 12 P31751,P31749 2 +Snare interactions in vesicular transport 0.5677572812461666 0.9326935956106186 0.3509781925233861 1.0 0.7747201566674743 19 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +Hypertrophic cardiomyopathy hcm 0.5365089023243808 0.8245902208250031 0.4096042752215783 1.0 0.8672219005200428 11 P06756,P23229,P05556,P09493 4 +Vegf signaling pathway 0.5384882276693319 0.8202910895305593 0.4120501847774789 1.0 0.8672219005200428 13 P31751,P31749 2 +Apoptosis 0.5449780537351121 0.8084431492478709 0.4188355207668481 1.0 0.8713704512505691 22 P31751,P10644,P31749,O95831,P17655,P07384 6 +Notch signaling pathway 0.516164165818724 0.7704659184477506 0.4410235643299403 1.0 0.877200715865046 6 Q92542 1 +Epithelial cell signaling in helicobacter pylori infection 0.5334764279064824 0.7547137142783067 0.4504207759557923 1.0 0.8848151224920558 21 P61421,Q16539,Q9Y487,Q15904,Q9Y624,Q93050 6 +Steroid biosynthesis 0.5141767488328439 0.7121608170984175 0.4763651974415364 1.0 0.8848151224920558 12 Q9UBM7,P48449,P38571,Q15392 4 +Amino sugar and nucleotide sugar metabolism 0.5253209350046145 0.6994293753918406 0.4842837351646618 1.0 0.8848151224920558 26 Q8NBZ7,P06865 2 +Non small cell lung cancer 0.4983070806407443 0.6315430202691086 0.5276855295352973 1.0 0.9386671978669958 13 P31749 1 +Nitrogen metabolism 0.4803661056982563 0.6295750144266429 0.5289726750410695 1.0 0.9386671978669958 4 P08243,O94925,P32929 3 +Endometrial cancer 0.4881413236359005 0.5781868769861932 0.5631379576852256 1.0 0.978499638445029 14 P31749 1 +Chronic myeloid leukemia 0.488497384970988 0.5488753925155574 0.5830909664699346 1.0 0.9863501395425996 19 O15111,P31751,P31749 3 +Leukocyte transendothelial migration 0.4846630341484442 0.5118942136826126 0.6087250480432516 1.0 1.0 23 P05556,P15311,Q16539,P60953,Q13464,P61586,P12814,Q9Y624 8 +Tight junction 0.4806020713645069 0.4676757890859568 0.6400164573648732 1.0 1.0 38 Q8N3R9,P35580,O60645,P30154,Q9UDY2,P60953,Q15334,P31751,P31749,P61586,P19784,P16989,P12814,Q9Y624 14 +Natural killer cell mediated cytotoxicity 0.4625909164065931 0.4449623989228776 0.6563469274886649 1.0 1.0 17 P10321,P01889 2 +Tgf beta signaling pathway 0.4468152167675069 0.4304692373207657 0.6668543396464237 1.0 1.0 10 Q13616,P30154,Q13464,P61586 4 +Chemokine signaling pathway 0.4612145129473859 0.3968814421685868 0.6914548897390802 1.0 1.0 25 O15111,P60953,P31751,Q13464,P61586,P31749,Q9UBI6,P40763 8 +Adherens junction 0.4585154970520503 0.393849241273321 0.6936923472273844 1.0 1.0 23 P60953,O43707,P19784,P61586,P12814,Q9UQB8,P08069,P10586 8 +Vibrio cholerae infection 0.4542841110470251 0.3804493221923521 0.7036119082860464 1.0 1.0 22 Q9UDY2,P61421,O43731,Q15904,Q93050 5 +Adipocytokine signaling pathway 0.442022000856921 0.3722021625803235 0.7097423360781145 1.0 1.0 15 P40763,P31751,P31749 3 +Pathogenic escherichia coli infection 0.450168779297549 0.3578476323407814 0.7204573422663216 1.0 1.0 23 P05556,P15311,P60953,P63104,Q13885,Q13464,P61586,O75116,P04350,O15511,Q9BUF5 11 +Endocytosis 0.4180185275216962 0.2248763663477622 0.8220754553583294 1.0 1.0 58 Q9Y6I3,P10321,Q9UQ16,Q9Y3E7,Q9H4M9,P46934,Q9H223,P01889,Q9BRG1,Q9UN37,P08069,P02786,P04439 13 +Proteasome 0.4179772783921676 0.1794168919963285 0.857610368696079 1.0 1.0 36 P49721,P28074,P28072 3 +Aldosterone regulated sodium reabsorption 0.3643127952473229 0.1648385318974523 0.8690710747991395 1.0 1.0 7 P54709,P05023,P05026,O00459 4 +Glioma 0.3888989861848023 0.1638373869791403 0.8698591587861191 1.0 1.0 17 P08069,P31751,P31749 3 +Colorectal cancer 0.3897850602831583 0.1600752830151433 0.8728217713786939 1.0 1.0 18 P31749 1 +Proximal tubule bicarbonate reclamation 0.3563105855274595 0.1346088093046673 0.892921176187224 1.0 1.0 8 P54709,Q9UBX3 2 +Glycerophospholipid metabolism 0.3771120125927353 0.1342056689432098 0.8932399432994691 1.0 1.0 16 Q8NCC3,Q9HBU6 2 +T cell receptor signaling pathway 0.3801216515523424 0.123558786065662 0.901664626305418 1.0 1.0 19 P31751,Q16539,P31749 3 +Retinol metabolism 0.3295924394565966 0.093054115200003 0.925860569967969 1.0 1.0 5 O94788,P11766,Q8TC12,Q9BTZ2 4 +Nod like receptor signaling pathway 0.3363599263356449 0.063585573459817 0.949300219206174 1.0 1.0 11 Q16539 1 +Long term depression 0.3392708234973163 0.0563054207104667 0.9550985005851048 1.0 1.0 13 P08069,P29992 2 +Porphyrin and chlorophyll metabolism 0.3295583295063237 0.0292134363601896 0.9766943651420577 1.0 1.0 14 P08236,Q5JPH6 2 +Wnt signaling pathway 0.3646077831327992 0.0247441549157687 0.9802590353204248 1.0 1.0 29 P30154,Q8TAA9,Q9BZK7,Q13555,Q9Y297,P56545,P19784,P61586,Q13616 9 +Erbb signaling pathway 0.3242243177309079 0.0125904310548897 0.9899545548470616 1.0 1.0 15 P31749 1 +Axon guidance 0.3441509365868448 0.0057744564268438 0.9953926759747084 1.0 1.0 23 O94813 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..059134881e7e3d2449876790bc9fb9fbfb88663e --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALYREF", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARFGAP1", "ARFGAP2", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "B4GALT1", "B4GALT3", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT1", "BCAT2", "BCKDHA", "BET1", "BIRC6", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BRK1", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP3", "CASP7", "CBR1", "CCDC12", "CCDC6", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKN2A", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHST12", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAPK3", "DARS", "DARS2", "DBT", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", 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+Gpcr ligand binding 5 11 2.305683290383356 0.0211283354599232 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0053489875931027 0.0014522342124754 0.0096938597365547 0.0008076868843539 0.0228888281479028 +Amyloid fiber formation 3 7 2.2942366185054475 0.0217769109940044 2.233009708737864 6.37378640776699 -0.2774936642640803 0.43935586458948 1.249884526667495 1.3460089271800024 1.1189280269465711 0.3074138199875801 0.0038617442022808 0.0010375212435442 0.0070463522145746 0.0170966332614883 0.1361773244383703 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 1 5 2.259037210833548 0.0238810703012484 2.04126213592233 5.614077669902913 -0.0251900596633248 0.4801240918435122 1.587495542145962 1.7303952839243353 1.0004234150191544 0.2910170854119779 0.1769084608978667 0.1157751708195439 0.2147385524083838 0.4600796867443816 0.3442759855295882 +Akt phosphorylates targets in the cytosol 2 5 2.2556500758188185 0.024092554473033 1.587378640776699 4.099514563106796 0.3752948860677916 0.4520588034670387 1.3089074679074084 1.79056311511362 1.1975044924591285 0.327626573781101 1.0 1.0 1.0 0.0442367692127036 0.0277461310389573 +Traf6 mediated nf kb activation 1 5 2.2312850141517453 0.0256622556988241 1.800970873786408 5.669902912621359 0.1650864411930541 0.5327423914035455 1.5102237438317596 1.6436896071200986 0.9190666419337 0.3058592578453835 0.1574312068776012 0.1026081339138497 0.191600110602388 0.4185863086244521 0.2898287915273368 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 9 19 2.1638561964765923 0.0304753876280918 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 6.891158442972939e-05 7.311012307953125e-06 0.0001918494429453 0.0003882882695527 0.0003148605079885 +G beta gamma signalling through pi3kgamma 2 5 2.1250981069117785 0.0335784275161332 1.1585365853658536 3.2 0.3450590652620733 0.4642099635318155 1.005709459513131 1.322967838777279 1.2134822090669073 0.3360720727637872 1.0 1.0 1.0 0.005208827916976 0.0334620993119388 +Metabolism of fat soluble vitamins 2 7 2.1097377585079164 0.0348809502534022 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.2021881519424126 0.0087935329278829 0.031373049189738 0.0326106125072858 0.1645088237572309 +Constitutive signaling by akt1 e17k in cancer 2 6 2.068282056856816 0.0386135080167113 1.9296116504854368 5.266990291262136 0.3564799056299969 0.5059420021573545 1.4934799541528836 1.8841643791539875 1.007824838624244 0.3184496724089312 1.0 1.0 1.0 0.1227655047468798 0.1188827437046941 +Formation of the cornified envelope 2 6 2.03661934433944 0.041688202738205 2.8470873786407767 5.691747572815534 -0.6850619911507018 0.3520169434460188 1.399866936164618 1.016671637173928 1.2355195198288238 0.313798966027817 0.1704659530663174 0.1114073342812727 0.2070995190727305 0.1147066696002357 0.1083207684216986 +Keratinization 2 6 2.03661934433944 0.041688202738205 2.8470873786407767 5.691747572815534 -0.6850619911507018 0.3520169434460188 1.399866936164618 1.016671637173928 1.2355195198288238 0.313798966027817 0.1704659530663174 0.1114073342812727 0.2070995190727305 0.1147066696002357 0.1083207684216986 +Hemostasis 37 137 2.0309925359274827 0.0422557517753359 23.70873786407767 121.62864077669904 -0.1302504040085788 0.6859796633498921 9.138769507748338 12.539276356734876 0.8159691531438237 0.3286641842384732 0.0606638855233024 0.2601152732882323 0.058643083881615 6.788410626686711e-05 0.0052490602596121 +Degradation of the extracellular matrix 4 10 2.006234522004876 0.0448312322670434 2.9854368932038833 8.45631067961165 -0.2764356066249684 0.4712903139856545 1.609975442554694 2.058733228327538 1.0124241638389404 0.2958639735684837 0.0697969048198253 0.2412174988663298 0.1009015630926116 0.0468842932022872 0.1344751100046247 +Translation of sars cov 1 structural proteins 1 7 2.000660686562443 0.0454289688034932 2.4223300970873787 6.516990291262136 0.2000582351843073 0.5481069552771392 1.643252283063436 0.9715380009471484 0.8883530031630541 0.303698878937936 1.0 1.0 0.191600110602388 0.0990342687178565 0.2898287915273368 +Myogenesis 2 7 1.9744912599819355 0.0483259102707116 2.6820388349514563 5.900485436893204 -0.2871255530687708 0.5704513904494223 1.7203430789152083 0.8109084904506817 0.7851856159818318 0.2874730218033769 0.1574312068776012 0.1026081339138497 0.191600110602388 0.4185863086244521 0.088385561156941 +Transport of inorganic cations anions and amino acids oligopeptides 4 11 1.972405813040184 0.0485632987804456 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.2903420469021255 0.1948770046367652 0.3467918934582977 0.2903927816552063 0.0605931687414638 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eed586d69c884322153da65f92d1cf65b1521cb4 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 1404, + "title": "Average number of proteins per term", + "value": 20.076210826210826 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f3aaea4632cc12d9e7db37d4935481a8dad41435 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..15f489c9bc4c14ff9252b341d097251abb66a901 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,457 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Neutrophil degranulation 0.6479133665240449 5.774056956665462 7.738525903928382e-09 1.0864831389850485e-05 1.0864890370519448e-05 191 Q08722,O15126,P10321,P07858,P07602,P34059,P17900,Q9UJU6,P16278,O00584,Q13576,P11717,Q99536,O75629,P07384,P04066,Q16539,P06280,P08236,Q8N1F8,Q9BTY2,P68402,P01889,P15586,P53634,Q9UNP9,P10253,Q93050,O60784,Q92820,P10619,P13473,P11279,Q9NV96,Q96BM9,Q13510,P07686,P15291,P61916,P27105,O15260,P42785,P61160,P04439,O00462,Q99519,Q8WVQ1,P06756,O00754,O00560,Q92542 51 +Innate immune system 0.550450802939479 5.2985479029276945 1.1672725510887721e-07 0.0001638716473137 8.194253308713379e-05 301 Q08722,P10321,P07858,P07602,P34059,Q9UQ16,P17900,P05067,Q04656,P16278,O00584,Q13576,P11717,Q99536,O75629,P07384,P04066,Q16539,P06280,Q99538,P28070,P08236,Q8N1F8,Q9BTY2,P68402,P01889,P15586,P53634,Q9UNP9,P10253,Q93050,O60784,Q8IV08,Q92820,P10619,P04114,P13473,P11279,Q9NV96,P49721,Q96BM9,P61421,Q13510,P07686,P15291,P61916,P27105,Q13685,O15260,P42785,P04439,O00462,Q99519,Q8WVQ1,O00754,O00560,Q9UQB8,P28074,P28072,Q92542 60 +Vesicle mediated transport 0.4635839497686741 3.852997485988748 0.0001166805889374 0.1511129198660017 0.0546065156227198 273 O60645,Q99523,Q8TD16,Q9UQ16,Q9UIQ6,Q9NVZ3,Q8TAG9,P05067,Q13190,P98164,Q16706,O75976,O43752,Q9UNS2,P11717,Q9NSK0,P02786,Q07954,O15027,Q12907,Q9Y6B6,Q5KU26,O00461,Q9Y3E7,O43493,Q14108,Q8WTV0,P68402,Q10472,Q92783,P20645,P15586,P84085,Q14671,P53634,Q9Y6I3,P04114,P31751,P62258,O43731,O60333,Q9Y3P9,O15260,Q5JRA6,P61160,Q14203,P39880,Q9Y496,O95486,P31749,Q04917,O14657,Q9UBW8,P31946,Q9BT78,Q10471,Q9BRG1,Q9UN37,Q92572 59 +Metabolism of carbohydrates 0.5560111255257895 3.780030869444118 0.0001568089160528 0.1976232204073922 0.0550399295345517 104 Q7LGA3,O00462,O60512,P34059,P06865,Q93063,O00754,P08236,P07686,Q11206,P16278,Q9NRB3,P54802,Q9P2E5,P15586,O43505,P10253,Q8NCH0 18 +Membrane trafficking 0.4437462587093215 3.4931710846054056 0.0004773205966281 0.488454175283962 0.1139511760276355 265 O60645,Q99523,Q8TD16,Q9UQ16,Q9UIQ6,Q9NVZ3,Q8TAG9,P05067,Q13190,P98164,Q16706,O75976,O43752,Q9UNS2,Q9NSK0,P11717,P02786,O15027,Q12907,Q9Y6B6,O00461,Q9Y3E7,O43493,Q14108,P68402,Q10472,Q92783,P20645,P15586,P84085,Q14671,P53634,Q9Y6I3,P04114,P31751,P62258,O43731,O60333,Q9Y3P9,O15260,Q5JRA6,P61160,Q14203,P39880,Q9Y496,O95486,P31749,Q04917,O14657,Q9UBW8,P31946,Q9BT78,Q10471,Q9BRG1,Q9UN37,Q92572 56 +Cs ds degradation 0.9772794334611968 2.880780499273083 0.0039669179765118 0.9962298071343496 0.1139511760276355 2 P06865 1 +Diseases associated with o glycosylation of proteins 0.9737385659486574 2.866339157367737 0.0041524911005943 0.9970976537975614 0.1139511760276355 2 Q9UHI8 1 +Trafficking and processing of endosomal tlr 0.9698037849785968 2.8471638816227824 0.0044110647948818 0.9979843920820264 0.1139511760276355 3 P07858 1 +Hs gag biosynthesis 0.9687223369725568 2.8458374891950062 0.0044294794011292 0.9980360613947248 0.1139511760276355 2 Q7LGA3 1 +Transport of small molecules 0.4427707354468925 2.844446237351931 0.0044488693015922 0.9980890373109202 0.1139511760276355 167 P08195,Q9UBX3,Q9C0H2,P30825,O15118,Q04656,Q9UBI6,P08183,P38571,Q9UNS2,P02786,Q9H2J7,Q9Y6B6,P28070,Q8WTV0,Q9BU23,P51797,Q8NB49,Q70HW3,Q15904,Q93050,P04114,P61421,P51790,Q13555,Q9Y487,P49721,P40855,P61916,Q8TAD4,P27105,Q9NQ11,Q9NWR8,P35670,P10644,P51798,P28074,P28072 38 +Keratan sulfate degradation 0.9592439456585914 2.7983906015835416 0.0051357963731073 0.999274926831406 0.1139511760276355 5 P15586,P06865,P07686,P34059 4 +Hs gag degradation 0.950413223140493 2.767135820349814 0.0056551189395441 0.9996516567489548 0.1139511760276355 3 P54802,P16278 2 +Heparan sulfate heparin hs gag metabolism 0.9509746012994658 2.763881748937243 0.0057118234861841 0.9996784605963284 0.1139511760276355 5 Q7LGA3,P54802,Q93063,P16278 4 +Mucopolysaccharidoses 0.9509746012994652 2.763881748937243 0.0057118234861841 0.9996784605963284 0.1139511760276355 5 P15586,P54802,P16278,P34059 4 +Maturation of protein 3a 0.9477722041900234 2.759662934604749 0.0057861025944976 0.999710478599602 0.1139511760276355 2 Q11206 1 +Vitamin d calciferol metabolism 0.9466450771355148 2.748447991579656 0.005987813351505 0.9997822494281624 0.1139511760276355 4 Q99538,P98164 2 +Intrinsic pathway of fibrin clot formation 0.9448214812629055 2.7474539255838013 0.0060059946821775 0.9997877702000714 0.1139511760276355 2 P42785 1 +Formation of fibrin clot clotting cascade 0.9448214812629055 2.7474539255838013 0.0060059946821775 0.9997877702000714 0.1139511760276355 2 P42785 1 +Scavenging by class b receptors 0.942460902921216 2.737673893276657 0.0061875398181987 0.9998357783985352 0.1139511760276355 2 Q8WTV0 1 +Akt phosphorylates targets in the nucleus 0.942165830628501 2.7364505867759807 0.0062105921497752 0.9998410405110264 0.1139511760276355 2 P31749 1 +Chondroitin sulfate biosynthesis 0.94010032457952 2.727882443550851 0.0063742319736912 0.999873853461892 0.1139511760276355 2 Q9NRB3 1 +Noncanonical activation of notch3 0.9395101799940956 2.7254327952996835 0.0064217248198124 0.9998820412588444 0.1139511760276355 2 Q92542 1 +Chondroitin sulfate dermatan sulfate metabolism 0.9409332545776694 2.721788250638205 0.00649297317788 0.999893339374125 0.1139511760276355 5 Q9NRB3,P06865,Q8NCH0,P07686 4 +N glycan antennae elongation 0.9391971664698912 2.7204944544188128 0.0065184365223269 0.9998971092822724 0.1139511760276355 3 Q11206,O60512 2 +Keratan sulfate biosynthesis 0.9394744611750858 2.7184750084903393 0.0065583609992188 0.999902753931866 0.1139511760276355 4 O43505,Q11206,O60512 3 +Keratan sulfate keratin metabolism 0.9408633944411526 2.716992314388968 0.0065878137454318 0.9999067187345166 0.1139511760276355 9 O60512,P34059,P06865,P07686,P16278,P15586,O43505,Q11206 8 +Diseases associated with glycosaminoglycan metabolism 0.9397519196692228 2.7168223293876497 0.0065911979746076 0.9999071638312048 0.1139511760276355 5 P06865,Q93063,Q8NCH0,P07686 4 +Endosomal vacuolar pathway 0.9350457632122842 2.699910037472384 0.0069358228210854 0.9999429636836948 0.1139511760276355 4 Q9UIQ6,P10321,P01889 3 +Hyaluronan uptake and degradation 0.9300532253025556 2.678932668575002 0.0073857243721615 0.9999698112120832 0.1139511760276355 4 P06865,P07686 2 +Hyaluronan metabolism 0.9300532253025556 2.678932668575002 0.0073857243721615 0.9999698112120832 0.1139511760276355 4 P06865,P07686 2 +O linked glycosylation of mucins 0.9291199054932044 2.671998295216048 0.0075401031505588 0.9999757335908052 0.1143005463725866 5 Q86SF2,Q10472,Q11206,O43505 4 +O linked glycosylation 0.9293943870014774 2.670617355220928 0.0075711900375003 0.999976777659154 0.1143005463725866 6 Q86SF2,Q10472,Q9UHI8,O43505,Q11206 5 +Tryptophan catabolism 0.9247565653585084 2.663958662264698 0.0077227052108272 0.9999812583516988 0.1153476395319311 2 P08195 1 +Glycosaminoglycan metabolism 0.921021810683605 2.6526891394071725 0.0079853375326641 0.9999870759041708 0.1161942855304183 19 Q7LGA3,O60512,P34059,P06865,P08236,Q9P2E5,Q93063,P16278,P07686,Q9NRB3,P54802,P15586,O43505,Q11206,Q8NCH0 15 +Reactions specific to the complex n glycan synthesis pathway 0.9203304809678284 2.6454287673210097 0.0081587462875905 0.9999898887738105 0.1161942855304183 2 P04066 1 +Synthesis of pyrophosphates in the cytosol 0.9197403363824082 2.642955047759358 0.0082185945826931 0.99999071012076 0.1161942855304183 2 Q13572 1 +N glycan antennae elongation in the medial trans golgi 0.9211458948611884 2.638225302193249 0.0083341190871157 0.9999921117402129 0.1161942855304183 5 P15291,P04066,O60512,Q11206 4 +Runx2 regulates genes involved in cell migration 0.9159016844966762 2.6227911111283957 0.0087212725715273 0.9999954408470976 0.1200457518669055 3 P31749 1 +Sialic acid metabolism 0.8982445354813967 2.535376273501989 0.0112326600398264 0.999999870540379 0.1388079539024334 7 Q99519,Q11206,P10619 3 +Elastic fibre formation 0.8863971673059909 2.502011249769754 0.0123490000819663 0.999999973495178 0.1388079539024334 2 P06756 1 +Molecules associated with elastic fibres 0.8863971673059909 2.502011249769754 0.0123490000819663 0.999999973495178 0.1388079539024334 2 P06756 1 +Adaptive immune system 0.4057525558841359 2.5015654902203215 0.0123645571620614 0.9999999740749088 0.1388079539024334 197 P10321,P07858,P05556,O15111,Q9UQ16,Q9UIQ6,P63104,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,Q9NZ08,Q9NSK0,Q9BUF5,O95239,P30154,Q9Y6B6,P52888,Q5KU26,P28070,Q99538,Q9UJX4,Q9UBG0,P01889,P55786,P78310,P53634,O94822,P10619,P31751,Q9Y297,P49721,P62942,Q15386,P49720,P20618,P60604,P04439,Q14203,Q6P179,Q9Y496,Q13867,Q9UJX5,P06756,P46934,O95486,P31749,Q9GZZ9,P31946,Q13616,Q6UWE0,P28074,P28072 53 +Regulation of tp53 activity through association with co factors 0.887301587551241 2.501291321104145 0.0123741343283891 0.9999999744254804 0.1388079539024334 3 P31749 1 +Ecm proteoglycans 0.8744661444705946 2.4418422503646577 0.0146125302002229 0.9999999989425062 0.1467506998488811 4 P06756,P05067 2 +Downregulation of erbb2 erbb3 signaling 0.8732072955430941 2.440782805241107 0.0146554660025866 0.9999999990052616 0.1467506998488811 3 P31749 1 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.8719519177861945 2.4309644324190516 0.0150586927317668 0.99999999944007 0.1467506998488811 4 P00374,P31749 2 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8706513253706726 2.429764808943375 0.0151086234227328 0.9999999994785386 0.1467506998488811 3 P05067 1 +Class a 1 rhodopsin like receptors 0.8727633942438732 2.422343144657087 0.0154207814382112 0.999999999665856 0.1467506998488811 8 P04083,P05067,P07602,P42892 4 +Peptide ligand binding receptors 0.8727633942438732 2.422343144657087 0.0154207814382112 0.999999999665856 0.1467506998488811 8 P04083,P05067,P07602,P42892 4 +Amino acid transport across the plasma membrane 0.8689059404752806 2.4177680463462052 0.0156160277319898 0.9999999997470668 0.147146999568549 4 Q9H2J7,P08195 2 +Diseases of carbohydrate metabolism 0.8681993073220184 2.398694554081275 0.0164536332194606 0.9999999999234486 0.1528082373194552 11 P34059,P16278,P54802,P15586,P10253 5 +Cd28 dependent pi3k akt signaling 0.8638038281012221 2.3956196042475537 0.0165922999388856 0.9999999999371968 0.1528082373194552 4 P31749 1 +Binding and uptake of ligands by scavenger receptors 0.8667830525606028 2.3942987361834507 0.0166521797078893 0.999999999942343 0.1528082373194552 9 Q07954,Q5KU26,Q8WTV0 3 +Laminin interactions 0.8584590224028645 2.3723584367158175 0.0176749347884102 0.9999999999866236 0.1560812142545447 4 P06756,P23229 2 +Glycosphingolipid metabolism 0.8578996806971428 2.3571864113881738 0.018414000586997 0.9999999999953504 0.1576418099033162 17 Q99519,P10619,P07602,P06280,P06865,P04062,P17900,Q13510,P07686,P16278 10 +Integrin cell surface interactions 0.8552686396398486 2.350147722278547 0.0187659617769666 0.9999999999971898 0.1587193393666336 6 Q08722,P23229,P06756,Q9Y624 4 +Stimuli sensing channels 0.8520676080629693 2.330751016368519 0.0197664923846134 0.9999999999993292 0.1630292691129015 8 Q9C0H2,P51797,P27105,P51790 4 +Gpcr ligand binding 0.8475082139266974 2.3056832903833557 0.0211283354599232 0.9999999999999049 0.1704838102628286 11 P04083,P07602,P05067,P42892,Q9UBI6 5 +Amyloid fiber formation 0.843294219696858 2.2942366185054475 0.0217769109940044 0.9999999999999624 0.1717684440201251 7 Q08431,P05067,Q9Y287 3 +Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.8355962219598494 2.2772607822765347 0.0227706573770158 0.999999999999991 0.1776111275407239 3 Q9Y624,P62942 2 +Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.8337000125346437 2.259037210833548 0.0238810703012484 0.9999999999999982 0.1832187032948239 5 P05067 1 +Akt phosphorylates targets in the cytosol 0.8329354013167145 2.2556500758188185 0.024092554473033 0.9999999999999988 0.183836665652926 5 P31751,P31749 2 +Traf6 mediated nf kb activation 0.8274434325101817 2.2312850141517453 0.0256622556988241 1.0 0.1906581443232753 5 P05067 1 +Receptor type tyrosine protein phosphatases 0.822661552080264 2.2261008222968512 0.0260074288830352 1.0 0.1921364948307983 2 P10586 1 +Tight junction interactions 0.8208911183239727 2.2183148612874626 0.0265333715817845 1.0 0.1931840034107745 2 Q9Y624 1 +Scavenging by class a receptors 0.8233334745667524 2.2179840392282144 0.0265559206967802 1.0 0.1931840034107745 4 Q5KU26 1 +Zinc efflux and compartmentalization by the slc30 family 0.8191206845677113 2.2105223591058833 0.0270689305088538 1.0 0.1946337173984536 2 Q8TAD4 1 +Assembly of collagen fibrils and other multimeric structures 0.8213188621020009 2.209051072267244 0.0271710887536302 1.0 0.1946337173984536 4 P07858 1 +P38mapk events 0.8167060212514685 2.1940076011753624 0.0282348631036941 1.0 0.2012271461806426 3 P11234,Q16539 2 +Chylomicron assembly 0.8145797550601677 2.1845899334543346 0.0289189266840841 1.0 0.2040310204243926 3 Q9Y6B6 1 +Notch4 activation and transmission of signal to the nucleus 0.80879315432279 2.1649360681758982 0.0303925815857648 1.0 0.2107755873391182 2 Q92542 1 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.8157027952490453 2.1638561964765923 0.0304753876280918 1.0 0.2107755873391182 19 P04114,O43493,P19022,P05067,Q9BTY2,O43852,Q06481,Q5JRA6,Q08431 9 +G beta gamma signalling through pi3kgamma 0.8036732965702251 2.1250981069117785 0.0335784275161332 1.0 0.2223778878898637 5 Q9UBI6,P31749 2 +Metabolism of fat soluble vitamins 0.8022105136558414 2.1097377585079164 0.0348809502534022 1.0 0.224646119980627 7 P98164,Q07954 2 +Enos activation 0.795733232360671 2.0948657213841195 0.0361829308036107 1.0 0.23071717740537 4 P31749 1 +Constitutive signaling by akt1 e17k in cancer 0.7921987897670312 2.0682820568568157 0.0386135080167113 1.0 0.2409482900242789 6 P31751,P31749 2 +Molybdenum cofactor biosynthesis 0.7831030195596879 2.0380011360983374 0.0415498192539618 1.0 0.2555905530324887 4 Q9Y697 1 +Formation of the cornified envelope 0.7852280386920589 2.0366193443394396 0.041688202738205 1.0 0.2555905530324887 6 Q14126,Q14574 2 +Keratinization 0.7852280386920589 2.0366193443394396 0.041688202738205 1.0 0.2555905530324887 6 Q14126,Q14574 2 +Hemostasis 0.396710311585376 2.0309925359274827 0.0422557517753359 1.0 0.2579438064894418 137 Q08722,P05556,P07602,P08195,P54709,Q96N67,Q9UNF1,P05067,Q96ST3,Q06481,Q9UBI6,Q92520,P23634,Q9NSK0,Q9Y624,Q9BUF5,P30154,Q16539,P61586,P78310,Q08380,Q92896,Q07021,P23229,P04114,P13473,O60333,Q13685,P42785,Q9Y496,Q9H4M9,P06756,P10644,P31749,O43852,Q13572,P29992 37 +Arms mediated activation 0.7751549129536599 2.0149342816873728 0.0439115354169483 1.0 0.2623480669165766 2 P31946 1 +Degradation of the extracellular matrix 0.781708910048294 2.006234522004876 0.0448312322670434 1.0 0.2667078394191906 10 P07858,Q92542,P17655,Q9UHI8 4 +Translation of sars cov 1 structural proteins 0.7782835341811376 2.000660686562443 0.0454289688034932 1.0 0.2679927403365735 7 Q11206 1 +Myogenesis 0.7725807727979718 1.9744912599819353 0.0483259102707116 1.0 0.2771661442591287 7 Q92859,Q16539 2 +Transport of inorganic cations anions and amino acids oligopeptides 0.7749886332485512 1.9724058130401836 0.0485632987804456 1.0 0.2771661442591287 11 Q9H2J7,P08195,P30825,Q9UBX3 4 +Plasma lipoprotein remodeling 0.7562903909069985 1.9228109157937467 0.0545038007100193 1.0 0.3040826340318315 3 P04114 1 +Wnt mediated activation of dvl 0.7524343464148613 1.9123345989601104 0.0558332907228831 1.0 0.3080941147254649 2 P19784 1 +Notch3 activation and transmission of signal to the nucleus 0.7532989982714189 1.9091940976623931 0.0562370574303934 1.0 0.3080941147254649 3 Q92542 1 +Plasma lipoprotein assembly 0.7545783372599134 1.908398883040542 0.0563396811138523 1.0 0.3080941147254649 4 Q9Y6B6 1 +G protein beta gamma signalling 0.7569794001452193 1.9073074381624555 0.0564807875696029 1.0 0.3080941147254649 6 Q9UBI6,P31749 2 +Receptor mediated mitophagy 0.7526564344746081 1.906266909281714 0.0566155851845939 1.0 0.3080941147254649 3 P19784,Q96HS1 2 +Interleukin 37 signaling 0.7465680628171234 1.8784924595045045 0.0603138276430796 1.0 0.3196110055411719 3 P40763 1 +Estrogen dependent nuclear events downstream of esr membrane signaling 0.7492270854137406 1.877517757525488 0.0604471658640846 1.0 0.3196110055411719 5 P31749 1 +Ticam1 rip1 mediated ikk complex recruitment 0.7438772499262147 1.8734347978129449 0.061008368579084 1.0 0.3196110055411719 2 O15111 1 +Irak1 recruits ikk complex 0.7438772499262147 1.8734347978129449 0.061008368579084 1.0 0.3196110055411719 2 O15111 1 +Dna damage reversal 0.7458686773606057 1.868511106692934 0.0616908634657729 1.0 0.3219850271596474 4 Q9H1I8,Q9C0B1 2 +Plasma lipoprotein clearance 0.7511051974638112 1.8522637875079688 0.0639879530212828 1.0 0.3327373557106705 15 P61916,O15118,Q8WTV0,P38571 4 +Cd163 mediating an anti inflammatory response 0.7385659486573996 1.849220980572866 0.0644259104010722 1.0 0.3332527488592297 2 Q16539 1 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7450528543936407 1.8472687822392424 0.0647081950139045 1.0 0.3332527488592297 7 P10321,Q5KU26,P01889,P78310,P04439 5 +Glutamate neurotransmitter release cycle 0.7396047695717682 1.846641291292923 0.0647991456115169 1.0 0.3332527488592297 3 O75915 1 +Phosphorylation of emi1 0.7377716049470486 1.8382411653266095 0.0660268763648714 1.0 0.3370972160591983 3 P53350 1 +Transferrin endocytosis and recycling 0.7436754487962625 1.8251436740628149 0.0679793510273878 1.0 0.3415750493747521 11 Q15904,Q93050,P61421,P02786 4 +Activated tak1 mediates p38 mapk activation 0.7309243790029522 1.8068108228124704 0.0707917806429057 1.0 0.3524526951157432 3 Q16539 1 +Erbb2 regulates cell motility 0.7276482738270849 1.7992857532182267 0.0719734905376494 1.0 0.3536134618242315 2 P61586 1 +Intra golgi and retrograde golgi to er traffic 0.3948259129159089 1.789346507311095 0.0735590284856475 1.0 0.3566093995100166 103 Q8TD16,Q15102,Q13190,Q16706,O43752,Q9NSK0,P11717,P24390,Q9BUF5,O95239,O00461,O43493,Q9Y2V7,Q9P2W9,Q9NP72,P68402,Q10472,Q9H9E3,P20645,Q9H2M9,P84085,Q96MW5,P35606,Q8TBA6,P49755,O43731,Q13885,Q15042,O60333,O15260,O14579,Q14203,P39880,Q9Y496,P43034,Q9UBF2,Q9Y678,Q99747,Q10471,P04350,O00139,P18085 42 +Activation of bad and translocation to mitochondria 0.7332125955426118 1.7873172519040563 0.0738862272338336 1.0 0.3566093995100166 8 P31751,P62258,P31749,Q04917,P31946 5 +Class i mhc mediated antigen processing presentation 0.3803825745525457 1.7814959874370386 0.0748314598185138 1.0 0.3573583999496373 121 P10321,O15111,Q9UIQ6,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,Q9NZ08,Q9Y6B6,P52888,P28070,Q9UJX4,Q9UBG0,P01889,P55786,O94822,Q9Y297,P49721,Q15386,P49720,P20618,P60604,P04439,Q6P179,Q13867,Q9UJX5,P06756,P46934,O95486,Q9GZZ9,Q13616,Q6UWE0,P28074,P28072 34 +Flt3 signaling 0.7245078994726842 1.7632260863896003 0.0778623657395827 1.0 0.3647317485555344 5 P31749 1 +Ldl clearance 0.7305914538746794 1.7572640316304076 0.0788728155629581 1.0 0.3652605670941199 13 P61916,O15118,P38571 3 +Trans golgi network vesicle budding 0.7089556766092057 1.756127120846814 0.0790667051988609 1.0 0.3652605670941199 40 Q99523,O43493,P05067,Q92572,O75976,P20645,P15586,P11717,P02786 9 +Signalling to ras 0.7197128432730935 1.7478848641147502 0.0804839662732441 1.0 0.3697776415077517 4 P11234,Q16539 2 +Interferon alpha beta signaling 0.7264469437716212 1.7469698107547151 0.0806425749394712 1.0 0.3697776415077517 10 P10321,P01889 2 +Synaptic adhesion like molecules 0.7202979656500332 1.7316520691252957 0.0833355294271869 1.0 0.3739568813582538 7 P41440,P10586,O75955,Q15334 4 +Transport and synthesis of paps 0.7128946591914884 1.7314705097157277 0.0833678802458215 1.0 0.3739568813582538 2 O43252 1 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7146643129879167 1.724463294980361 0.0846242396753753 1.0 0.3772819031496072 4 Q9BZK7 1 +Regulation of localization of foxo transcription factors 0.715559863037692 1.7149621223839318 0.0863521716996342 1.0 0.3810645544809522 6 P31751,P31749 2 +Regulation of gene expression in beta cells 0.7104295336690983 1.7122406984530072 0.0868523201096187 1.0 0.3810645544809522 3 P31749 1 +Epha mediated growth cone collapse 0.7161294157452331 1.70694365006029 0.0878325265779516 1.0 0.3841646956867415 8 P35580,Q15375,P60660,Q13464,P61586,O75116 6 +Stat3 nuclear events downstream of alk signaling 0.706949719722281 1.6885911119595716 0.091297815130299 1.0 0.3941937079493075 4 P40763 1 +Netrin 1 signaling 0.71214963279472 1.68814814779048 0.0913827939073281 1.0 0.3941937079493075 8 Q92859,O94813 2 +Plasma lipoprotein assembly remodeling and clearance 0.715925002943202 1.678143391040417 0.0933191097285184 1.0 0.3970303941176966 19 Q9Y6B6,P04114,O15118,Q8WTV0,P61916,P38571 6 +Gap junction assembly 0.7031081376825343 1.6706921506655874 0.0947825000709428 1.0 0.3996235138126237 4 Q13885,Q9BUF5 2 +Transport of connexons to the plasma membrane 0.7031081376825343 1.6706921506655874 0.0947825000709428 1.0 0.3996235138126237 4 Q13885,Q9BUF5 2 +Diseases of glycosylation 0.7117826912754084 1.6582505998927846 0.0972668954614117 1.0 0.4088704228377907 21 Q99519,P10619,P06865,Q93063,P07686,P16278,Q9UHI8,O43505,Q8NCH0 9 +Sphingolipid metabolism 0.7062454728758538 1.6475419675630534 0.0994466974394527 1.0 0.411658632923997 28 Q99519,P10619,P07602,P06280,P06865,P17900,P04062,Q13510,P16278,P07686 10 +Glucagon signaling in metabolic regulation 0.7010666412276905 1.6469570299202154 0.0995668783823209 1.0 0.411658632923997 6 Q9UBI6 1 +Vasopressin regulates renal water homeostasis via aquaporins 0.7010666412276905 1.6469570299202154 0.0995668783823209 1.0 0.411658632923997 6 Q9UBI6 1 +Pre notch processing in golgi 0.6976363289742171 1.6377830947337402 0.1014669493178379 1.0 0.4120553824962246 5 Q11206 1 +Dcc mediated attractive signaling 0.6925346709943982 1.6372925467202255 0.1015693575158542 1.0 0.4120553824962246 2 P60953 1 +Nef and signal transduction 0.6925346709943947 1.6372925467202086 0.1015693575158578 1.0 0.4120553824962246 2 Q13177 1 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6925346709943927 1.6372925467202002 0.1015693575158596 1.0 0.4120553824962246 2 Q9Y490 1 +Mitochondrial iron sulfur cluster biogenesis 0.6936894953044991 1.6344809996513296 0.1021578926353596 1.0 0.4120553824962246 3 Q9Y697 1 +Sema4d induced cell migration and growth cone collapse 0.6996626487502806 1.6344756508863685 0.1021590148618338 1.0 0.4120553824962246 7 P35580,P60660,Q13464,P61586,O75116 5 +Adp signalling through p2y purinoceptor 1 0.6943011889664532 1.622134095382368 0.1047746391746136 1.0 0.4202959811461643 5 Q9UBI6,Q16539 2 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7007171798664944 1.6201850444443615 0.1051925330710925 1.0 0.4207701322843702 11 Q13685,P05067,Q16539 3 +Ion channel transport 0.6963858000723878 1.6163185366615456 0.1060254610877056 1.0 0.4228970095657348 32 Q13555,P61421,P51790,Q9NQ11,Q9C0H2,P54709,Q9Y487,Q04656,P35670,P51798,P51797,P27105,Q8NB49,Q15904,Q93050 15 +Golgi associated vesicle biogenesis 0.69266398012915 1.590542029562035 0.1117126796544967 1.0 0.4356393977717636 31 P11717,Q99523,O75976,P02786 4 +Diseases of mismatch repair mmr 0.6794569067296322 1.5680381170984052 0.1168722369890513 1.0 0.44603750089586 3 P52701,P20585 2 +Sumo is transferred from e1 to e2 ube2i ubc9 0.674535261138981 1.5535157763101364 0.1202999632207535 1.0 0.452818092123158 2 Q9UBE0 1 +Sumo is conjugated to e1 uba2 sae1 0.674535261138981 1.5535157763101364 0.1202999632207535 1.0 0.452818092123158 2 Q9UBE0 1 +Thromboxane signalling through tp receptor 0.6747895599999755 1.5228613213655424 0.12779340436245 1.0 0.4712491561050341 6 Q9UBI6,Q13685 2 +Activation of rac1 downstream of nmdars 0.6662732369430522 1.5149162969046115 0.1297936027241741 1.0 0.47579691442491 2 P63000 1 +Metabolism of nitric oxide nos3 activation and regulation 0.6723635035064799 1.5113578416724556 0.1306973043433681 1.0 0.4778620190054397 6 P31749 1 +Cd28 co stimulation 0.6745907904971806 1.5095848998669126 0.1311493767764542 1.0 0.4782694155691993 8 P31749 1 +Rora activates gene expression 0.6666910864873998 1.4999444986327142 0.1336287799434687 1.0 0.4860487229031869 4 Q86X55 1 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.6691722416739494 1.4897421465988578 0.1362920481222107 1.0 0.486152396973723 7 Q9UBI6 1 +Cargo recognition for clathrin mediated endocytosis 0.6659800776849167 1.486066842365617 0.1372614416345836 1.0 0.486152396973723 37 Q9Y6I3,P04114,O43493,Q9NVZ3,Q14108,P98164,O14657,Q9UBW8,P20645,Q9UNS2,P11717,P02786 12 +Rhob gtpase cycle 0.6768571215091826 1.4826828471808131 0.1381586940117631 1.0 0.486152396973723 23 P41440,Q8TAA9,Q9UDY2,Q14254,O75955,Q13464,P43121,P14923,P27105,P02786 10 +Activation of bh3 only proteins 0.6725523170368871 1.479887657261467 0.1389032301340913 1.0 0.4866826158683123 12 P31751,P62258,P31749,Q04917,P31946 5 +Dap12 interactions 0.6635460293158657 1.469490946139038 0.1416996757492175 1.0 0.4924414474056964 6 P10321 1 +Rho gtpases activate ktn1 0.6653459042900293 1.4653473897728742 0.1428261632778156 1.0 0.4927075994385669 8 P60953,P61586,P63000,P84095,Q9NSK0,P33176 6 +Regulation of tnfr1 signaling 0.6609698834320702 1.464908267744638 0.1429459468108418 1.0 0.4927075994385669 5 Q8TCT8 1 +Insulin receptor recycling 0.6668430985613036 1.4614869699431408 0.1438818488388977 1.0 0.4927075994385669 10 Q15904,P61421,Q93050 3 +Cell surface interactions at the vascular wall 0.6687021965771153 1.443365868902318 0.1489174334993863 1.0 0.5073007976820001 18 Q08722,P23229,P04114,P08195,P06756,P78310,Q92896,Q9Y624 8 +Rho gtpase cycle 0.3525110733577865 1.4392576649225193 0.1500775327303447 1.0 0.5073007976820001 159 Q96AC1,P05556,Q14254,Q7L576,Q96N67,Q13190,P51648,Q14739,O75976,Q9P2R3,Q13576,P02786,Q96HY6,P67936,Q13464,P61586,Q8NBN3,P12814,Q92783,Q14126,Q15904,Q07021,Q5T0N5,Q8TAA9,P60953,Q9BX68,Q8IYB3,P43121,Q6IAA8,Q5VTR2,Q68EM7,P15924,P27105,P41440,Q9Y512,Q9UDY2,O75489,P52565,O75955,Q9P0I2,P14923,Q9BT78,Q9UQB8,Q96RT1,O15173 45 +Gpvi mediated activation cascade 0.6570162481536208 1.4384326033341328 0.1503113474613333 1.0 0.5073007976820001 6 P60953,P61586,P63000,P84095,Q06124 5 +Runx1 regulates transcription of genes involved in bcr signaling 0.649454116258486 1.436097214818868 0.1509746805260288 1.0 0.5079254325835293 2 Q13951 1 +Striated muscle contraction 0.6555712309835555 1.4315538261829646 0.1522715520875632 1.0 0.5090220455498543 6 P09493 1 +Tnf signaling 0.6557997335196313 1.4259105263650818 0.1538941705542325 1.0 0.511183066675435 7 Q8TCT8 1 +Ephrin signaling 0.6496303966232027 1.419391625855842 0.1557848724742703 1.0 0.511183066675435 4 O00560,Q13177 2 +Signal amplification 0.6566172620983025 1.4175733959838637 0.156315351902303 1.0 0.511183066675435 9 Q13685,Q9UBI6,Q16539 3 +Lysosome vesicle biogenesis 0.6609371464866852 1.4119482689994791 0.1579651936685555 1.0 0.5133868794228055 15 P05067,P15586 2 +Ras activation upon ca2 influx through nmda receptor 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2 +Long term potentiation 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2 +Unblocking of nmda receptors glutamate binding and activation 0.648967106026038 1.4079795814167233 0.1591371162320984 1.0 0.5136287613560143 5 Q13555,Q14168 2 +Bmal1 clock npas2 activates circadian gene expression 0.6470877996424614 1.3990543654248344 0.1617966808907649 1.0 0.5210149999326467 5 Q86X55 1 +Vegfr2 mediated vascular permeability 0.6528810825553563 1.3939642494072817 0.163328400717498 1.0 0.52390121433188 10 P31749 1 +Metabolism of lipids 0.3388240258759039 1.3881823861586764 0.1650815144002 1.0 0.5259693752311373 198 P07602,P17900,P04062,Q15392,P16278,P98164,Q9UMR5,Q9Y6B6,P06280,Q99538,Q93074,P06865,Q8TBX8,Q9HBU6,P50897,Q8IV08,P10619,Q13510,P07686,Q86X55,P48449,Q8NCC3,Q99519,Q9BV79 24 +Aquaporin mediated transport 0.6466211448628896 1.3820007334188225 0.1669714759117468 1.0 0.5279908832884969 7 Q9UBI6 1 +Activation of nima kinases nek9 nek6 nek7 0.6423791934179209 1.3766799651287964 0.1686112156299373 1.0 0.5307850823866187 5 P53350,P06493 2 +G protein activation 0.6396368290210946 1.3720824781300502 0.1700377634427003 1.0 0.5309107964518986 4 Q9UBI6 1 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.6367706719597714 1.367300351229925 0.1715311816660176 1.0 0.5316330663556044 3 P61586 1 +Rap1 signalling 0.6352504871563189 1.360120826176996 0.1737916916425268 1.0 0.5338090467092285 3 P31946 1 +Nod1 2 signaling pathway 0.6415409839336094 1.3576695096246527 0.1745685758764359 1.0 0.5339744673867451 7 Q13685,Q16539 2 +Attachment of gpi anchor to upar 0.6378820000369549 1.3552952564157466 0.1753235057374456 1.0 0.53511783055516 5 Q9H490 1 +Repression of wnt target genes 0.6301652892561814 1.3360940820193077 0.1815185240808292 1.0 0.5470745942190395 3 Q13547,P56545 2 +Telomere c strand synthesis initiation 0.631183139153532 1.332008123363219 0.182857519164884 1.0 0.5481273695117324 4 P49643 1 +Syndecan interactions 0.6345455734802945 1.3312720018370825 0.1830995272799163 1.0 0.5481273695117324 6 P06756,P23229,P05556 3 +Response to elevated platelet cytosolic ca2 0.6396177721730163 1.3195055479158295 0.1870001566018497 1.0 0.5552083695134581 34 P07602,P13473,P05067,O43852,Q06481,Q08380 6 +Defective intrinsic pathway for apoptosis 0.642917595591733 1.319366264706256 0.1870466942876536 1.0 0.5552083695134581 16 Q07021,P05067,P07384,P17655 4 +Extracellular matrix organization 0.6386390029521813 1.3043196110756123 0.1921246314949085 1.0 0.5654989153435044 32 Q08722,P13674,P05556,P07858,P23229,P06756,P05067,O15460,Q92542,P17655,Q9UHI8,Q9Y624,P07384 13 +Signaling by erbb4 0.6283063515766223 1.2942111655807864 0.1955924910623543 1.0 0.5721080363573864 7 P46934,Q92542 2 +Downregulation of erbb2 signaling 0.6245538395141939 1.2692666902786118 0.2043459623503274 1.0 0.5855137370201219 8 P31749 1 +Non integrin membrane ecm interactions 0.6192889268093871 1.2509347534472357 0.2109582830715608 1.0 0.5944044076973084 7 P06756,P23229,P05556 3 +Signaling by receptor tyrosine kinases 0.341247250102585 1.239790111300732 0.2150530367425684 1.0 0.5944044076973084 119 P05556,Q9UQ16,Q7L576,Q96N67,Q96ST3,P08069,P30154,Q16539,Q92783,Q15904,Q9Y6I3,Q93050,P31751,P61421,Q9Y487,Q96S59,Q13685,P06756,P46934,P13984,P11234,P31749,P31946,Q9UQB8,P40763,Q92542 26 +Smooth muscle contraction 0.6232034106086414 1.2387627436990674 0.2154333748913657 1.0 0.5944044076973084 12 P04083,P09493,P60660,P14649 4 +Extra nuclear estrogen signaling 0.6236235255784268 1.2311994116539573 0.2182482914171783 1.0 0.5944044076973084 14 Q9UBI6,P31751,P31749 3 +Abc transporters in lipid homeostasis 0.6074405870702808 1.2285953324653602 0.2192235663684414 1.0 0.5944044076973084 3 P40855 1 +Signaling by hippo 0.6116132556845582 1.2216414661135016 0.2218432404796222 1.0 0.5944044076973084 6 Q9UDY2,P62258 2 +Ptk6 regulates proteins involved in rna processing 0.6022425494246155 1.2137388236486242 0.2248474739535217 1.0 0.5978898739218648 2 Q07666 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.6096341094074857 1.2121762379753505 0.2254449253409398 1.0 0.5983453216988271 6 Q13555,Q14168 2 +Egfr downregulation 0.6123306504742565 1.210366697529888 0.2261382148134938 1.0 0.5990529313172555 8 P60953,P42566,Q92783,Q9UBC2,Q9Y6I3 5 +Basigin interactions 0.6078020236583078 1.1957936065453658 0.2317771115094218 1.0 0.6082524571200528 7 P54709,P23229,P05556,P08195 4 +Ion transport by p type atpases 0.6160559560273042 1.1894306091386586 0.2342702618220902 1.0 0.6125054890097108 15 Q13555,Q9NQ11,P54709,P20020,P35670,Q04656,P05026,P23634,Q8NB49 9 +Mastl facilitates mitotic progression 0.5982293095336768 1.1755659174777962 0.2397683817708367 1.0 0.6222454861483452 4 P06493 1 +Nr1h2 and nr1h3 mediated signaling 0.5993408185870854 1.1629592787071807 0.2448460245235479 1.0 0.6307592998735071 6 Q8NB78,Q9BZK7 2 +Eph ephrin mediated repulsion of cells 0.6056686796862947 1.1528860463819703 0.2489571600854385 1.0 0.6332171245651372 12 Q92542 1 +Clathrin mediated endocytosis 0.5575622341616439 1.1446602008970832 0.2523499439715262 1.0 0.6338132476314416 60 Q9Y6I3,P04114,Q9UQ16,O43493,Q9NVZ3,Q14108,P98164,O14657,Q9UBW8,P20645,Q9UNS2,P11717,P61160,P02786 14 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5874889347890292 1.1441756211315457 0.2525508112784291 1.0 0.6338132476314416 2 P24941 1 +Ptk6 regulates cell cycle 0.5874889347890292 1.1441756211315457 0.2525508112784291 1.0 0.6338132476314416 2 P24941 1 +Cargo concentration in the er 0.6068770072628845 1.1438860043466363 0.2526709159968754 1.0 0.6338132476314416 15 Q12907,Q9Y6B6,Q13190,Q5JRA6,P53634 5 +Diseases of metabolism 0.5890704384994775 1.138191756799687 0.2550404200069456 1.0 0.6360155411896121 47 Q99519,P10619,P34059,P08236,P06865,Q93063,P16278,P07686,P54802,P15586,Q9UHI8,O43505,P10253,Q8NCH0 14 +Map3k8 tpl2 dependent mapk1 3 activation 0.5908576519903327 1.1313240199939634 0.2579187380207131 1.0 0.6397156521594506 5 O15111,Q9Y297 2 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5942042648033226 1.1305545768588037 0.2582426150349348 1.0 0.6397156521594506 7 P31751 1 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5957096225828127 1.1303074280593546 0.2583467056797781 1.0 0.6397156521594506 8 Q86X55 1 +Adora2b mediated anti inflammatory cytokines production 0.5880037342804637 1.0860024691171777 0.277477899853233 1.0 0.6716878817136882 9 Q9UBI6 1 +Apoptotic cleavage of cell adhesion proteins 0.5822606001495709 1.0814003654648705 0.2795190591619405 1.0 0.6743037097308668 6 Q14126 1 +G alpha i signalling events 0.5984765769392838 1.0771955841973175 0.2813928976312465 1.0 0.6764897587736184 27 P04083,Q9UBI6,P05067,P07602 4 +Rhoc gtpase cycle 0.5964798857806923 1.0750495089641872 0.2823525631348578 1.0 0.6764897587736184 32 P41440,Q8TAA9,Q9UDY2,Q14254,P52565,O75955,Q13464,Q13190,P61586,P43121,P14923,Q14739,P27105,Q07021,P02786 15 +Heme signaling 0.5820121787112087 1.0721533891425798 0.2836511420359318 1.0 0.6769061523379547 7 Q86X55,P04114 2 +Interleukin 4 and interleukin 13 signaling 0.5891927416214064 1.0665882289343485 0.2861578182092832 1.0 0.6788515231096389 13 P04083,P40763,P31749 3 +Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5772031785772991 1.0664076862204592 0.2862393886616141 1.0 0.6788515231096389 5 P49643,P30154 2 +Prolactin receptor signaling 0.5744796366892129 1.0629860864763343 0.287788261066956 1.0 0.6813738929814608 4 Q13616,Q9Y297 2 +Antigen presentation folding assembly and peptide loading of class i mhc 0.591983392632618 1.061447548508384 0.2884865578823552 1.0 0.6818773186310214 17 P10321,Q9Y6B6,Q6P179,P01889,P04439 5 +Signaling by insulin receptor 0.5910048797332522 1.056561239827829 0.2907118779639304 1.0 0.6839247116726216 17 Q15904,P61421,P31751,Q93050 4 +Rnd1 gtpase cycle 0.5857289483204408 1.0391523745278386 0.2987338759565556 1.0 0.6944078838460334 15 Q8TAA9,O75976,P02786 3 +Regulation of beta cell development 0.5681130052305825 1.0328950434562187 0.3016530185828343 1.0 0.7000344431244618 4 P31749 1 +G alpha 12 13 signalling events 0.5706489438586744 1.017861324131773 0.308743863861149 1.0 0.7117838831872796 7 Q9UBI6,Q13464,P61586 3 +Iron uptake and transport 0.5823154280643479 1.0092707921449395 0.3128447837811041 1.0 0.7200558629978201 18 Q15904,Q93050,P61421,P02786 4 +Nef mediated downregulation of mhc class i complex cell surface expression 0.5622021426054195 1.005008189755891 0.3148929063311985 1.0 0.7229234784855981 4 Q9BXS5,P04439 2 +Sema4d in semaphorin signaling 0.5711860693824566 0.9978431059572704 0.3183554439847489 1.0 0.7257454135539795 10 P35580,P60660,Q13464,P61586,P35579,O75116 6 +Rho gtpases activate iqgaps 0.5709383113905528 0.996648556124486 0.3189351283210864 1.0 0.7257454135539795 10 P60953,Q13885,P46940,P04350,Q13576,Q9BUF5 6 +Visual phototransduction 0.5698408859881559 0.9913586381685932 0.3215104895164167 1.0 0.7304218888042865 10 P98164,Q07954 2 +Glutathione synthesis and recycling 0.5629317637824487 0.9894606397936784 0.3224378182660841 1.0 0.7313452291527981 6 Q8WUX2 1 +Diseases associated with glycosylation precursor biosynthesis 0.5676795970193061 0.9809467341419944 0.3266190095079184 1.0 0.7372557706577452 10 Q99519,P10619 2 +Foxo mediated transcription 0.5665634658676888 0.9755731453306534 0.3292760378497603 1.0 0.7408710851619608 10 Q96ST3,P31946,P31751,P31749 4 +Programmed cell death 0.3193209634058754 0.9739916212243036 0.3300606994796531 1.0 0.7414483553110928 108 Q9UJU6,P28070,Q9Y3E7,O43293,Q14126,Q07021,P31751,P62258,P49721,P49720,P41440,Q9UDY2,P26583,O75955,P31749,Q04917,P31946,O00560,P40763,P28074,P28072 21 +Post translational modification synthesis of gpi anchored proteins 0.5518277160261984 0.9283949597122804 0.3532027320885507 1.0 0.7772674543139894 7 O43292,Q9ULX3,Q9H490 3 +Rhoa gtpase cycle 0.5502427292432753 0.9138608820254782 0.360789950683543 1.0 0.790013655373989 48 P41440,Q8TAA9,Q9UDY2,Q96HY6,P52565,O15173,O75955,P61586,Q13190,Q8NBN3,P43121,Q14739,Q9P0I2,P27105,Q15904,Q07021,P02786 17 +Assembly and cell surface presentation of nmda receptors 0.5505169292256407 0.8986100060126088 0.368860427132061 1.0 0.8016718880702998 10 Q13555,Q15334,Q13885,Q14168,Q9BUF5 5 +Mtorc1 mediated signalling 0.549082229448404 0.8917594077642991 0.3725219033823801 1.0 0.8081430744374957 10 P23588,Q6IAA8,P31946,P62942 4 +Mtor signalling 0.5542662573777072 0.8845407773026641 0.3764043601607054 1.0 0.8125772161153412 15 P31751,P62942,P31749,P31946,P23588 5 +Abortive elongation of hiv 1 transcript in the absence of tat 0.5511664027221195 0.875180548494733 0.381475675224098 1.0 0.8176974778849366 14 Q8IXH7,P18615 2 +Signaling by notch1 pest domain mutants in cancer 0.5397580846137878 0.8714460251031447 0.3835106647368365 1.0 0.8208063617233513 7 Q92542 1 +Cell cell junction organization 0.5445395175857691 0.8701066761992228 0.3842421095579698 1.0 0.8211201245348395 10 Q9BY67,Q9Y624 2 +Transport of bile salts and organic acids metal ions and amine compounds 0.536696260866169 0.8657978684106056 0.3866010183449906 1.0 0.8241102278790886 6 Q9H2J7 1 +Vitamin b2 riboflavin metabolism 0.5225730303924577 0.8411476663840874 0.4002652143983116 1.0 0.8463439171916107 2 P22413 1 +Pi3k akt signaling in cancer 0.541807585678922 0.8362088254889892 0.4030374343139717 1.0 0.8483050113916493 13 P31751,P31749 2 +Mhc class ii antigen presentation 0.521189015994976 0.8319727862573054 0.405424305480214 1.0 0.8483050113916493 56 Q9Y496,P07858,Q9Y6B6,P10619,Q99538,P53634,Q9NSK0 7 +Small interfering rna sirna biogenesis 0.524516523984474 0.8289665428218805 0.4071233395067291 1.0 0.8493330886589118 4 Q15631 1 +Metabolism of cofactors 0.529094827569401 0.8214970578281771 0.4113631992833344 1.0 0.8556354545093355 7 P00374,P31749 2 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.533284311054095 0.8092955827721022 0.4183451464360137 1.0 0.8637596847002401 11 P06493,P31946,P62258,Q04917 4 +Retrograde transport at the trans golgi network 0.5417043420292984 0.7992145966239799 0.4241659895559695 1.0 0.864338242868768 20 O43752,P11717,O43493 3 +Bicarbonate transporters 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.8697861918826691 2 Q9Y6M7 1 +Ros and rns production in phagocytes 0.524763469780362 0.7845447284889526 0.432720547268671 1.0 0.8697861918826691 9 P61421,Q93050 2 +Intra golgi traffic 0.5376709517673023 0.7835265792342202 0.4333179517932062 1.0 0.8697861918826691 19 P39880,O00461,Q16706,Q13190,O43752,Q96MW5,Q8TBA6 7 +Runx1 regulates expression of components of tight junctions 0.509884921805845 0.7831757936485821 0.4335238875529821 1.0 0.8697861918826691 2 Q13951 1 +Regulation of tp53 activity through acetylation 0.5307036998947132 0.7647272130658714 0.4444339980759433 1.0 0.8825818009881533 16 Q8TBX8,P31749 2 +Glycogen metabolism 0.5216133599640672 0.746999074352739 0.4550641195824187 1.0 0.8998732730897407 12 P10253,P46020 2 +Asparagine n linked glycosylation 0.3078963313503347 0.7418392391041262 0.4581847432108019 1.0 0.903499128466244 128 Q99519,P04066,P10619,Q9Y6B6,O60512,O43731,P16278,Q13190,P15291,Q16706,P84085,P53634,Q11206 13 +Collagen formation 0.5236762766157879 0.7369362174596151 0.4611611379949538 1.0 0.9055527800628184 15 P23229,P13674,P07858,O15460 4 +Transcriptional regulation of white adipocyte differentiation 0.5213812000796132 0.7323166068815731 0.4639753454160304 1.0 0.9071748770879828 14 Q86X55,Q93074 2 +Inla mediated entry of listeria monocytogenes into host cells 0.4980820300973865 0.7298598044606301 0.4654758841859954 1.0 0.9071748770879828 2 P35222 1 +Signal transduction by l1 0.5121763350524036 0.7260592816036501 0.4678024294955125 1.0 0.9071748770879828 9 P06756,P05556 2 +Platelet calcium homeostasis 0.5009715912986812 0.7213910590980169 0.4706689460063757 1.0 0.91021928401233 4 P20020,P23634 2 +Reduction of cytosolic ca levels 0.5009715912986812 0.7213910590980169 0.4706689460063757 1.0 0.91021928401233 4 P20020,P23634 2 +P75ntr negatively regulates cell cycle via sc1 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.9212074846253246 2 Q13547 1 +Signaling by notch1 0.5027719860856557 0.6913562463029921 0.4893416930138059 1.0 0.9284266716099776 8 Q92542 1 +Protein protein interactions at synapses 0.5122690817625813 0.6829498179564955 0.4946385527424077 1.0 0.9353422360844904 15 P41440,Q15334,O75955,Q9UJU6,Q14168,Q13136,P10586 7 +Translation of sars cov 2 structural proteins 0.5140402006554636 0.6794369224044862 0.4968610619003737 1.0 0.936480506364777 17 Q10472,Q11206 2 +Synthesis of diphthamide eef2 0.4881936245572626 0.6747871443901801 0.4998110091427215 1.0 0.9370710750537268 3 P13639,Q9BQC3 2 +Transport to the golgi and subsequent modification 0.4023517369403696 0.6746396650871016 0.4999047259367817 1.0 0.9370710750537268 85 Q13190,Q16706,P24390,Q9BUF5,O15027,O95487,Q9Y6B6,P04066,Q12907,O60512,Q9Y2V7,Q9H9E3,P84085,P53634,Q96MW5,P35606,P49755,O43731,Q13885,P15291,Q92734,Q5JRA6,O14579,Q11206,Q14203,O94979,Q9UBF2,Q9Y678,Q99747,P04350,O95486 31 +Adherens junctions interactions 0.4978670185339686 0.6690801402108675 0.5034443577959045 1.0 0.9386638964365784 8 Q9BY67 1 +Thrombin signalling through proteinase activated receptors pars 0.495370961753854 0.6666547333667696 0.5049926992618756 1.0 0.9390857612763884 7 Q9UBI6 1 +Interferon gamma signaling 0.5056129584497896 0.6652134984899388 0.5059139479820227 1.0 0.9395544748237564 13 P10321,P01889,P04439 3 +Synthesis of substrates in n glycan biosythesis 0.5105077778889351 0.6472386593232371 0.5174774944607485 1.0 0.9490607657662512 20 Q99519,Q11206,P10619 3 +Formation of the early elongation complex 0.5064990027798217 0.6438089916128942 0.5196993023653049 1.0 0.9490607657662512 17 Q8IXH7,P18615 2 +Regulation of mecp2 expression and activity 0.4931693190419359 0.6310457255626487 0.5280106270457929 1.0 0.9594443597353196 10 Q96ST3,Q13555,Q9BZK7 3 +Diseases of programmed cell death 0.5059740681680026 0.6093700548400431 0.5422791818941559 1.0 0.9723329115765796 24 Q07021,P05067,P07384,P17655 4 +Deactivation of the beta catenin transactivating complex 0.491702736198826 0.608780554833719 0.5426699041660232 1.0 0.9723329115765796 12 P31751,P31749,Q9Y297 3 +Antigen processing cross presentation 0.4849642636780265 0.6012668836336248 0.5476622429472515 1.0 0.9745472612141206 56 P10321,P28070,Q9UIQ6,P49721,P01889,Q9UBG0,P28074,P28072 8 +Anti inflammatory response favouring leishmania parasite infection 0.4913542916189132 0.5998310233528332 0.5486188555608631 1.0 0.9750137635537364 13 Q9UBI6,P10644 2 +Loss of function of mecp2 in rett syndrome 0.4722711750774614 0.5838360776885042 0.559330602904859 1.0 0.991540614240432 5 Q9BZK7 1 +Post translational protein modification 0.2825190372587056 0.570503988573449 0.5683359176440321 1.0 0.9999293588624324 413 P05067,P16278,Q13190,Q06481,Q08431,Q9Y6B6,P04066,O60512,P28070,Q86SF2,O43493,Q9BTY2,Q10472,P53634,P04114,P10619,Q9HA64,O43731,P49721,P15291,Q5VTR2,Q9UHI8,P60604,O43505,Q11206,Q9BTE7,P04439,Q99519,Q9NXR7,O43852,Q9UBW8,P28074,P28072 33 +Cd28 dependent vav1 pathway 0.4663480909254215 0.5687230140340087 0.5695441271253827 1.0 1.0 4 P60953,Q13177 2 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4814418668742954 0.5627209000562454 0.5736249501800597 1.0 1.0 12 P05067,P46379,Q13190 3 +Signaling by notch3 0.4688376620192936 0.5588663136380967 0.576252960966293 1.0 1.0 6 Q92542 1 +Intrinsic pathway for apoptosis 0.494520387353779 0.5581569121156341 0.5767372407041489 1.0 1.0 23 P31751,P62258,P31749,P31946,P40763,Q07021 6 +Maturation of sars cov 2 nucleoprotein 0.463241806908775 0.5554442742244233 0.5785908163191633 1.0 1.0 4 Q99873,Q96SB4,P48729 3 +Ion homeostasis 0.4769579048872506 0.550671646791533 0.5818587844089036 1.0 1.0 11 Q13555,P54709,P20020,P05026,P23634 5 +Cardiac conduction 0.4769579048872506 0.550671646791533 0.5818587844089036 1.0 1.0 11 Q13555,P54709,P20020,P05026,P23634 5 +Developmental biology 0.2856454056244929 0.5457753018529862 0.5852204025767596 1.0 1.0 265 Q15375,Q9BZK7,Q9UQ16,Q92859,P07384,P63220,Q14574,Q16539,P62857,P28070,Q93074,Q14126,P36896,O94813,P60660,P31751,P49721,A0MZ66,Q86X55,P61160,P06756,P31749,O00560,P40763,P28074,P28072,Q92542 27 +Ctla4 inhibitory signaling 0.4700087560039167 0.5456068700538454 0.5853362009110725 1.0 1.0 8 P31749 1 +Muscle contraction 0.4932355319823908 0.5415556229593746 0.5881246697392175 1.0 1.0 26 P04083,P60660,Q13555,P54709,P20020,P09493,P67936,P14649,P05026,P23634,Q13177 11 +Regulation of runx1 expression and activity 0.4560212514757988 0.5355525447612407 0.5922678335496359 1.0 1.0 3 Q13951,Q06124 2 +Toll like receptor cascades 0.4931149630833764 0.5335942001177493 0.5936223218361945 1.0 1.0 29 P07858,P04114,Q9UQ16,Q99538,P05067 5 +Cross presentation of soluble exogenous antigens endosomes 0.4921556989947828 0.5292010703887582 0.5966659742382698 1.0 1.0 39 P28074,P49721,Q9UBG0,P28072 4 +Signaling by met 0.4805499243003794 0.5182634384980797 0.6042744784960459 1.0 1.0 18 O14964,P05556,P40818,Q96S59,Q96N67,P42566,Q92783,P40763,P20338,Q06124 10 +Activated ntrk2 signals through cdk5 0.4488049572145179 0.5163837339964036 0.6055864241634423 1.0 1.0 2 P63000 1 +Cell junction organization 0.4821765632776804 0.5145851050176329 0.6068429757729996 1.0 1.0 20 P23229,Q96AC1,P05556,Q9BY67,P19022,P12814,Q9Y624 7 +Signaling by ptk6 0.4671898371651232 0.5080762375636058 0.6113998790497581 1.0 1.0 11 P31749 1 +Ngf stimulated transcription 0.4489374262101561 0.5060150856561173 0.6128460594430707 1.0 1.0 3 P50570,Q14839 2 +Rhoj gtpase cycle 0.4831947968532034 0.5050781876104847 0.6135039209189512 1.0 1.0 23 Q5T0N5,Q8TAA9,P60953,P14923,Q6IAA8,P27105,P51149,P02786,Q13177 9 +Antigen processing ubiquitination proteasome degradation 0.3414010089907772 0.4922747660266665 0.6225251162717038 1.0 1.0 94 Q9UIQ6,Q9C0C9,Q9H1A4,Q99436,Q9ULT8,P52888,P28070,Q9UJX4,P55786,O94822,Q9Y297,P49721,Q15386,P49720,P20618,P60604,Q13867,Q9UJX5,P46934,Q9GZZ9,Q13616,Q6UWE0,P28074,P28072 24 +Cell death signalling via nrage nrif and nade 0.4588786723295754 0.4892423323403251 0.6246701427009442 1.0 1.0 9 Q92542 1 +Cyclin a cdk2 associated events at s phase entry 0.4799662535373066 0.4796565316827444 0.6314716414796657 1.0 1.0 44 P28070,P49721,P31749,P28074,P28072 5 +Signaling by vegf 0.4800746903992652 0.4760113211850825 0.6340663124191612 1.0 1.0 27 Q16539,P31751,P60953,P06756,Q7L576,Q13464,P61586,P31749,P14923,Q13685,Q9UQB8,Q13177 12 +Carboxyterminal post translational modifications of tubulin 0.4462455072939882 0.4739107046116539 0.6355635853855868 1.0 1.0 5 Q13885,Q9BUF5 2 +Cargo trafficking to the periciliary membrane 0.4725737101996802 0.4711806818939859 0.6375117128191152 1.0 1.0 20 Q8TAG9,O60645,A6NIH7 3 +Fatty acyl coa biosynthesis 0.464586609569802 0.4601204687258539 0.6454297527845931 1.0 1.0 16 Q9UMR5 1 +Adenylate cyclase inhibitory pathway 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 1.0 2 P08754 1 +Maturation of sars cov 2 spike protein 0.4548690639255962 0.447670645091378 0.6543909101443559 1.0 1.0 12 Q11206 1 +Linoleic acid la metabolism 0.4311006196518105 0.4446301971305701 0.6565870212124132 1.0 1.0 2 O95864 1 +Rhog gtpase cycle 0.475656316879625 0.4415384121703749 0.6588232593649035 1.0 1.0 35 P05556,Q8TAA9,O75489,P52565,Q7L576,Q13190,P43121,Q6IAA8,Q14739,Q13576,Q14126,P02786 12 +Runx3 regulates p14 arf 0.4324085005903189 0.4390155844514021 0.6606502440577804 1.0 1.0 3 Q13951,P25440 2 +Rnd2 gtpase cycle 0.4609228880962508 0.4314959638776548 0.6661077867073713 1.0 1.0 18 Q8TAA9,P02786 2 +Diseases of signal transduction by growth factor receptors and second messengers 0.2887041722815285 0.4230090609968367 0.6722886501478413 1.0 1.0 151 O15111,Q9BZK7,P21359,Q9NRY5,P28070,P67936,P51797,Q13555,P31751,P49721,P62942,P56545,P49720,Q14203,P10644,P13984,P31749,P31946,P40763,P28074,P28072,Q92542 22 +Signaling by rho gtpases miro gtpases and rhobtb3 0.2795774253361188 0.4214647290095159 0.6734157614773566 1.0 1.0 262 Q96AC1,P05556,Q8NBT2,Q15334,Q14254,P63104,Q7L576,Q96N67,Q13190,P51648,Q14739,O75976,Q9P2R3,O15511,Q13576,Q9NSK0,P46060,Q9P258,P02786,Q9BUF5,P30154,Q16539,Q96HY6,P67936,Q13464,P61586,Q8NBN3,P12814,Q92783,Q14126,Q15904,Q07021,Q5T0N5,P35580,P53350,P60660,Q8TAA9,P60953,P62258,Q9BX68,Q8IYB3,Q13885,O14777,P43121,Q6IAA8,Q5VTR2,Q68EM7,P15924,P27105,Q8NFH3,P61160,P41440,Q9Y512,Q9UDY2,O75489,P52565,P43034,O75955,Q04917,Q9P0I2,P14923,Q9BT78,P31946,P04350,Q9UQB8,Q9BW27,Q96RT1,O15173 68 +Met promotes cell motility 0.4380276534411498 0.4211978259876832 0.6736106317367192 1.0 1.0 7 P05556 1 +Cell cell communication 0.4695087874254849 0.4185586719503996 0.6755386987658103 1.0 1.0 30 Q08722,Q96AC1,P05556,P23229,Q9BY67,Q9Y5K6,P19022,P12814,Q9Y624 9 +Condensation of prometaphase chromosomes 0.4430190043957746 0.4149781639430989 0.6781578883232444 1.0 1.0 10 P67870,P19784,Q9NTJ3,P06493 4 +Regulation of tp53 expression and degradation 0.4468352417148709 0.4143035700024971 0.6786517996732973 1.0 1.0 12 P31751,P31749,P06493 3 +Signaling by notch 0.4451065010993801 0.4136374910424824 0.679139612145663 1.0 1.0 61 P28070,P49721,P67809,P31749,P15291,P28072,P28074,Q11206,Q92542 9 +Hdr through mmej alt nhej 0.4383683121489548 0.4135271997799413 0.6792203985086553 1.0 1.0 8 Q92878,P18887,P49916,O60934,P49959,Q9UGN5,P39748 7 +Cdc42 gtpase cycle 0.4695660663411648 0.4124862369369538 0.6799830664304989 1.0 1.0 34 Q5T0N5,Q8TAA9,P60953,P52565,Q96N67,Q68EM7,Q6IAA8,P14923,Q14739,P27105,Q9UQB8,Q13576,P51149,P02786 14 +Hdms demethylate histones 0.4325939498418137 0.4088850455770352 0.6826240240187038 1.0 1.0 6 Q8NB78,Q7LBC6 2 +Regulation of tp53 activity through methylation 0.4219327110293139 0.3876799770121329 0.6982528751989807 1.0 1.0 4 Q9H9B1 1 +Interleukin 1 family signaling 0.4563590689711681 0.3868363468664731 0.6988773671012019 1.0 1.0 51 O15111,Q9Y297,P28070,P49721,P05067,Q9H3S7,P49720,P20618,P40763,Q13616,P28074,P28072 12 +Cyclin d associated events in g1 0.4315696127697113 0.3865725925424668 0.6990726514216934 1.0 1.0 8 P30154,P42771,P63208,P24941,P11802,Q13616,P63151 7 +Condensation of prophase chromosomes 0.4305352393989808 0.3825216273463843 0.7020744901116216 1.0 1.0 8 P53350,P06493,P42695,Q01105 4 +Class i peroxisomal membrane protein import 0.4362900171780437 0.3796757614631593 0.7041861147571018 1.0 1.0 11 Q9NR77,P51648,P40855,P56589 4 +Signaling by alk 0.4233486956082876 0.3729412899258176 0.7091921403910413 1.0 1.0 6 P40763 1 +Interleukin 1 signaling 0.4562970184845238 0.3699973300112559 0.7113844797995277 1.0 1.0 48 P28072,P49721,P28074,P05067 4 +Semaphorin interactions 0.4463606021740351 0.3637185524172457 0.7160681880724553 1.0 1.0 19 P35580,P05556,P60660,Q13464,P61586,Q9Y490,P35579,O75116,Q13177 9 +Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4376814099471979 0.3619502225070448 0.7173892285748227 1.0 1.0 14 Q9UBI6,P19784 2 +Ire1alpha activates chaperones 0.4546848704664374 0.3602655554931536 0.7186485550281441 1.0 1.0 27 P51858,P61421,O43909,O43731,O14773,Q14203 6 +Ca dependent events 0.4232264565154856 0.3542912197562343 0.7231206471921536 1.0 1.0 8 P10644 1 +Rhoq gtpase cycle 0.4470807231515399 0.3498448043272335 0.7264551721678032 1.0 1.0 22 P02786 1 +Signalling to erks 0.4283847822946418 0.3486454481061179 0.7273555033942931 1.0 1.0 11 P31946,P11234,Q16539,P11233 4 +Signaling by notch4 0.4548128773309879 0.3478967959509097 0.7279176916132428 1.0 1.0 44 P49721,P31749,P28074,P28072,Q92542 5 +Nephrin family interactions 0.4214795764484307 0.3476488514789988 0.7281039137964422 1.0 1.0 8 Q9Y5K6,P46940,O43707,P12814,Q13813 5 +Signaling by erbb2 0.4315368581212631 0.3451445206677601 0.7299857248565018 1.0 1.0 13 P31749 1 +Interleukin receptor shc signaling 0.4048391856004754 0.3447908504584942 0.7302516120561562 1.0 1.0 2 O00459 1 +Role of lat2 ntal lab on calcium mobilization 0.4048391856004754 0.3447908504584942 0.7302516120561562 1.0 1.0 2 O00459 1 +Pi 3k cascade fgfr1 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Pi 3k cascade fgfr3 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Activated ntrk2 signals through frs2 and frs3 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Frs mediated fgfr3 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Signaling by flt3 itd and tkd mutants 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Pi 3k cascade fgfr4 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Stat5 activation 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Pi 3k cascade fgfr2 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Stat5 activation downstream of flt3 itd mutants 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Frs mediated fgfr1 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Frs mediated fgfr2 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Frs mediated fgfr4 signaling 0.4048391856004719 0.3447908504584818 0.7302516120561655 1.0 1.0 2 Q06124 1 +Grb2 sos provides linkage to mapk signaling for integrins 0.4048391856004716 0.3447908504584803 0.7302516120561666 1.0 1.0 2 Q9Y490 1 +Shc1 events in erbb2 signaling 0.4048391856004715 0.3447908504584797 0.7302516120561671 1.0 1.0 2 Q05655 1 +Tie2 signaling 0.4049586776859521 0.3347663468475296 0.7378013484841255 1.0 1.0 3 Q06124,O00459 2 +Apoptosis 0.3259082475000481 0.3345771683096368 0.7379440702822144 1.0 1.0 94 Q9UDY2,P31751,P62258,P28070,P49721,P26583,Q9UJU6,P49720,P31749,Q04917,Q07021,O43293,P31946,P40763,Q14126,P28074,P28072 17 +Regulation of ras by gaps 0.4522371326294241 0.3286523978113715 0.7424184382934138 1.0 1.0 40 P21359,P49721,P28074,P28072 4 +Copi independent golgi to er retrograde traffic 0.447373076050312 0.3284520646126034 0.7425698825078668 1.0 1.0 27 Q8TD16,Q13885,Q15102,P43034,Q9NP72,P68402,Q10472,P04350,Q10471,Q9H2M9,Q9BUF5,Q14203 12 +Constitutive signaling by overexpressed erbb2 0.4050782403306884 0.3249898145330167 0.7451887804715989 1.0 1.0 4 Q96RT1,Q16543,P07900 3 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4415607812397653 0.3217013034122148 0.7476789903217504 1.0 1.0 23 Q99519,Q11206,P10619 3 +Rac1 gtpase cycle 0.4496683055006893 0.3199579087755098 0.7490002384861669 1.0 1.0 43 Q96AC1,P05556,Q8TAA9,Q7L576,Q96N67,Q68EM7,P43121,Q6IAA8,Q14739,Q9UQB8,Q13576,P02786 12 +Rac3 gtpase cycle 0.4489691691883482 0.3148432916863782 0.752880640006468 1.0 1.0 35 Q96AC1,P05556,Q8TAA9,Q7L576,Q68EM7,P43121,Q6IAA8,Q14739,Q9UQB8,Q14126,P02786 11 +Metabolism of folate and pterines 0.411841026342152 0.3031215305888555 0.7617972465413723 1.0 1.0 9 P00374,P34896 2 +Signaling by egfr 0.4161032942175567 0.2941709119255588 0.7686273066796785 1.0 1.0 12 P60953,P42566,Q92783,Q9UBC2,Q13685,Q06124,Q9Y6I3 7 +Sema4d mediated inhibition of cell attachment and migration 0.3952380205605884 0.2902541382727611 0.7716218215840775 1.0 1.0 4 P61586 1 +Inlb mediated entry of listeria monocytogenes into host cell 0.400810610504466 0.2901408407462868 0.7717084925277811 1.0 1.0 6 P42566,Q92783 2 +Met activates ptpn11 0.3916765053128656 0.2880246963818328 0.7733278343589864 1.0 1.0 3 P62993,Q06124 2 +Pre notch expression and processing 0.4097340398055564 0.2789094277342072 0.7803143332495004 1.0 1.0 11 Q11206 1 +Negative regulation of the pi3k akt network 0.4210181050556118 0.2694522250505742 0.7875817018876945 1.0 1.0 18 Q8TBX8,P31749 2 +Slc mediated transmembrane transport 0.4311190356939103 0.2694345203473174 0.7875953246093252 1.0 1.0 25 Q9H2J7,P08195,P30825,Q9UBX3,Q8TAD4,Q70HW3,Q99808 7 +Cell extracellular matrix interactions 0.3961669173241925 0.2650878535681059 0.7909417841687687 1.0 1.0 7 Q96AC1,P05556 2 +Nrage signals death through jnk 0.3898405197873674 0.2621016931670603 0.7932430414433922 1.0 1.0 5 Q92974,P63000,Q14344,Q9NY61 4 +Platelet activation signaling and aggregation 0.421640703349173 0.2620122792408725 0.7933119753492213 1.0 1.0 60 P07602,P13473,P05067,P31749,O43852,Q9UBI6,Q06481,Q92520,Q08380 9 +Inositol phosphate metabolism 0.3946678707224149 0.2599764966839483 0.7948819033281154 1.0 1.0 7 Q13572 1 +Death receptor signalling 0.4243272503402004 0.2580559846480361 0.7963637004658368 1.0 1.0 22 Q8TCT8,O15111,P62258,P61586,Q92542 5 +Ripk1 mediated regulated necrosis 0.4024878812099881 0.2532517176067649 0.800073703864328 1.0 1.0 11 P41440,O00560,O75955 3 +Negative regulation of notch4 signaling 0.4342077134527048 0.244855881289734 0.8065680235567492 1.0 1.0 42 P49721,P28074,P28072,P31749 4 +Listeria monocytogenes entry into host cells 0.3922553946201429 0.243177243514487 0.8078680948605053 1.0 1.0 8 O14964,P62993,Q99961,O60716,P35222,P42566,Q92783 7 +Translocation of slc2a4 glut4 to the plasma membrane 0.4317815712564509 0.2346145812767419 0.8145078911859982 1.0 1.0 38 O60343,P61106,O60645,Q9UPT5,Q9Y496,P31751,P62258,P63104,Q8TAG9,Q9UIQ6,Q13885,P31749,Q04917,P11233,P31946,P04350,P20338,Q9BUF5 18 +Rnd3 gtpase cycle 0.4124893927490085 0.2314783355959316 0.8169432141343465 1.0 1.0 19 O75976 1 +Cd209 dc sign signaling 0.370315727353197 0.2284617635045269 0.8192872784131688 1.0 1.0 2 Q13177 1 +Phosphorylation of the apc c 0.3975538576780142 0.228419475156041 0.819320150625392 1.0 1.0 12 P53350,Q9UJX4,Q9UJX5,P06493 4 +Clec7a dectin 1 induces nfat activation 0.3691354381823535 0.224829580308471 0.8221118533671399 1.0 1.0 2 Q08209 1 +Leishmania infection 0.4275795654878773 0.2191716601876538 0.8265163306877912 1.0 1.0 36 Q16539,P10644,P05067,Q9UBI6,Q9UQB8 5 +Response of eif2ak1 hri to heme deficiency 0.3686540731995334 0.2136649780333857 0.8308083241030082 1.0 1.0 3 P08243,P20042 2 +Endosomal sorting complex required for transport escrt 0.3943291857056081 0.2099572242584519 0.8337010589564486 1.0 1.0 13 Q9UN37,Q92783,Q9Y3E7,Q9BRG1 4 +Post chaperonin tubulin folding pathway 0.3836222623733821 0.2066383135989211 0.8362923360552434 1.0 1.0 9 P68371,Q13885,Q9BTW9,P04350,Q9BUF5 5 +Regulation of ifng signaling 0.3659976387249131 0.2056721280918728 0.83704703164429 1.0 1.0 3 P42224,Q06124 2 +Regulation of ifna signaling 0.3659976387249131 0.2056721280918728 0.83704703164429 1.0 1.0 3 P42224,Q06124 2 +Wax and plasmalogen biosynthesis 0.3652199586654844 0.1939742437155947 0.8461960493910565 1.0 1.0 4 O15228,Q8WVX9,Q6IAN0 3 +Eph ephrin signaling 0.4178731767551946 0.1928058149569803 0.8471110492624827 1.0 1.0 31 Q15375,P35580,P60660,P59998,P60953,Q13464,P61586,O00560,O15511,P61160,Q92542,O75116,Q13177 13 +Rhoh gtpase cycle 0.4065998551600845 0.192404251671842 0.8474255622698572 1.0 1.0 22 Q8TAA9,P52565,Q13464,P14923,Q6IAA8,O75116,P27105,P51149,P02786,Q13177 10 +Dna replication initiation 0.3736500930120414 0.1923361811871593 0.8474788789486347 1.0 1.0 7 P49643,Q9NRF9,P49642 3 +Platelet sensitization by ldl 0.3744970278293841 0.1865501520238394 0.8520133534138925 1.0 1.0 8 P04114,Q16539 2 +E2f mediated regulation of dna replication 0.3763903656023042 0.1841228962608258 0.8539170449221682 1.0 1.0 9 P49643,P30154,P49642,P06493 4 +Rho gtpases activate cit 0.3779966392336619 0.1810165044258762 0.8563546213585573 1.0 1.0 10 P35580,P60660,Q15334,P61586 4 +Ovarian tumor domain proteases 0.3686314134807285 0.177353201546615 0.8592309642759126 1.0 1.0 7 P06493 1 +Vxpx cargo targeting to cilium 0.3736747326338193 0.1679628630136384 0.8666124949816059 1.0 1.0 10 O60645 1 +Negative regulation of met activity 0.3665385752290701 0.1630384210149791 0.8704881837814082 1.0 1.0 8 O14964,P62993,P40818,Q99961,Q9NWH9,P42566,Q92783 7 +Regulation of runx3 expression and activity 0.4141694597032031 0.1588521310199525 0.8737853756065108 1.0 1.0 39 P49721,P28074,P28072 3 +Sars cov 1 infection 0.3829477389168776 0.1588411083323637 0.8737940601790473 1.0 1.0 15 Q10472,Q11206 2 +Rac2 gtpase cycle 0.4119060369739182 0.1576470695249265 0.8747349111830025 1.0 1.0 35 P05556,Q8TAA9,P60953,Q9Y512,P52565,Q7L576,O15173,Q68EM7,P43121,Q6IAA8,Q14739,Q96RT1,Q14126,P51149,P02786,Q13177 16 +Hedgehog on state 0.4144935389975898 0.157638875881687 0.874741368033326 1.0 1.0 44 P49721,P28074,P28072,P28070 4 +Insulin processing 0.3770718460107837 0.1553110029310855 0.8765761417847115 1.0 1.0 13 Q8TAG9,O60645,Q8TAD4,Q8NEW0 4 +Sealing of the nuclear envelope ne by escrt iii 0.3697981504822164 0.1413321940011862 0.8876075177308107 1.0 1.0 12 Q9Y3E7,Q13885,P04350,Q8WUX9,Q9UN37,Q9BUF5 6 +Degradation of axin 0.4083706815989292 0.1372666910751816 0.8908199978482385 1.0 1.0 38 P49721,P28074,P28072 3 +Transcriptional regulation by runx2 0.4064937184465891 0.1353410759333703 0.8923422099275926 1.0 1.0 52 P28070,P49721,P31749,P28074,P28072 5 +Rho gtpases activate rocks 0.3622778150006679 0.1352638756049483 0.8924032456300002 1.0 1.0 10 P35580,P60660,Q13464,P61586,O75116 5 +Circadian clock 0.3700415305303955 0.1346858437662744 0.8928602662355827 1.0 1.0 13 Q9BZK7,Q9Y297,Q9BWF3,Q13616,Q86X55,P50416 6 +Degradation of dvl 0.4065450737518249 0.1283850137304827 0.8978442903194719 1.0 1.0 39 P49721,P28074,P28072 3 +Regulation of pten stability and activity 0.4073202738105229 0.1278613902086234 0.8982586663363912 1.0 1.0 46 P31751,P28070,P46934,P49721,P31749,P19784,P28074,P28072 8 +Metabolism of steroids 0.4061137501706751 0.1235244165644245 0.901691840724955 1.0 1.0 47 Q9UBM7,Q9Y6B6,Q9BZK7,Q99538,P04062,Q15392,O95772,P98164,Q86X55,P48449 10 +Scf skp2 mediated degradation of p27 p21 0.405732383162472 0.1224675758155358 0.9025287234148278 1.0 1.0 41 P49721,P28074,P28072 3 +Free fatty acids regulate insulin secretion 0.3371715382344299 0.1188559865667805 0.9053894521350234 1.0 1.0 4 O95573,O60488,P29992 3 +Hedgehog off state 0.3999907198378411 0.1118545812418815 0.9109387094456152 1.0 1.0 54 Q9Y496,Q9Y297,P28070,Q8NCM8,P49721,Q13885,P10644,P49720,P51665,P20618,Q99436,Q13616,P28074,P28072,Q9BUF5 15 +Neurexins and neuroligins 0.3472911349588249 0.1112580277847047 0.911411737682321 1.0 1.0 8 Q14168,Q9UJU6,Q15334 3 +Asymmetric localization of pcp proteins 0.4000741532171767 0.1035508304372996 0.9175258094270446 1.0 1.0 39 P49721,P28074,P28072 3 +E3 ubiquitin ligases ubiquitinate target proteins 0.3705711724359748 0.1020312850302829 0.9187318427961731 1.0 1.0 18 Q5VTR2 1 +Polo like kinase mediated events 0.3367799113737106 0.1013194236831908 0.9192968976669418 1.0 1.0 6 Q99640,P53350,P30307,Q09028,P14635 5 +G protein mediated events 0.357643523455001 0.1007363952209235 0.9197597191063184 1.0 1.0 13 P10644,Q13555 2 +Intracellular signaling by second messengers 0.292947756905742 0.1006349611156713 0.9198402426188048 1.0 1.0 96 O15111,Q13555,P31751,P28070,P46934,P49721,P10644,Q8TBX8,P31749,P19784,P28074,P28072 12 +Opioid signalling 0.3759543921229358 0.098948437913909 0.9211792096857488 1.0 1.0 21 Q9UBI6,P10644,Q13555,P29992 4 +G1 s specific transcription 0.347615918006147 0.097005229826911 0.922722241238183 1.0 1.0 10 P00374,P06493 2 +Signaling by interleukins 0.253392510091697 0.0962906000900339 0.9232897764385916 1.0 1.0 109 P04083,P05556,Q13277,Q16539,P28070,P49721,P05067,P31749,P40763,Q13126,P28074,P28072 12 +Downstream signaling events of b cell receptor bcr 0.3951644946096164 0.0784616997218325 0.9374607954587972 1.0 1.0 44 O15111,Q9Y297,P28070,P49721,P62942,P49720,P20618,Q13616,P28074,P28072 10 +Costimulation by the cd28 family 0.3541345000719472 0.0779784239980058 0.9378452158783248 1.0 1.0 15 P31749 1 +Notch1 intracellular domain regulates transcription 0.3256018866870629 0.0764890678368738 0.9390300110985031 1.0 1.0 6 Q9BZK7 1 +Intraflagellar transport 0.3448663673153541 0.0760105335158848 0.939410717910412 1.0 1.0 12 Q9Y496,Q13885,Q9BUF5,Q8NCM8 4 +Sensory perception 0.3801572480707391 0.0740603695843442 0.9409623491137182 1.0 1.0 28 P98164,Q07954 2 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3929649306930715 0.0721454277656194 0.9424861742623096 1.0 1.0 42 P49721,P28074,P28072 3 +Stabilization of p53 0.3921618381772686 0.0706895418741514 0.9436448443906646 1.0 1.0 41 P49721,P28074,P28072 3 +Purine salvage 0.3189604252805704 0.0706127326971246 0.9437059764836097 1.0 1.0 5 P00491,P55263,P07741,P00492 4 +Metabolism of polyamines 0.3907575649204265 0.0674295653655579 0.9462397329857246 1.0 1.0 40 P49721,P28074,P28072 3 +Cdt1 association with the cdc6 orc origin complex 0.3900631337409987 0.0649523678626506 0.9482119250612278 1.0 1.0 40 P49721,P28074,P28072 3 +Apc c cdc20 mediated degradation of cyclin b 0.3360020775546481 0.0627983961273727 0.9499270430550156 1.0 1.0 11 Q9UJX4,Q9UJX5,P06493 3 +Rho gtpases activate paks 0.3357349428683132 0.0622125208470068 0.9503935916115328 1.0 1.0 11 P35580,P60660,P60953,Q14247,P35579,Q13177 6 +Protein ubiquitination 0.3710742736891383 0.0522467348418813 0.9583320947405692 1.0 1.0 27 Q5VTR2,P60604 2 +Signaling by gpcr 0.3881805915661124 0.0507160217244118 0.9595518095888372 1.0 1.0 46 P04083,P31751,P07602,Q9BYT8,P05067,P31749,P42892,Q9UBI6 8 +Dna damage recognition in gg ner 0.3501960609133418 0.0489618424909234 0.9609497047293069 1.0 1.0 18 Q13619,Q9UBW8,Q9UNS2,Q9BT78 4 +Sumoylation of dna methylation proteins 0.3029229406554541 0.048407391229546 0.9613915688630136 1.0 1.0 4 Q9HC52,P26358,Q8IXK0 3 +G1 s dna damage checkpoints 0.386098444247685 0.0457434281909812 0.9635147493270916 1.0 1.0 43 P49721,P28074,P28072 3 +Ksrp khsrp binds and destabilizes mrna 0.3382068791580755 0.0407652081124394 0.9674830761943788 1.0 1.0 15 P31749 1 +Dag and ip3 signaling 0.3180546552800343 0.0401272385976724 0.9679916860250256 1.0 1.0 9 P10644 1 +Rhod gtpase cycle 0.3701514899758307 0.0400194657754495 0.9680776072788706 1.0 1.0 29 Q8TAA9,Q9BX68,Q68EM7,P43121,P12814,Q14739,O15173 7 +Copii mediated vesicle transport 0.3714718829696752 0.0348136137628779 0.9722283649994798 1.0 1.0 31 O15027,Q12907,Q9Y6B6,Q13190,P53634 5 +Meiotic recombination 0.3184592005187819 0.0341302642601315 0.9727732751482184 1.0 1.0 10 Q13472 1 +P75 ntr receptor mediated signalling 0.3318237804727334 0.0337942363862641 0.9730412320196038 1.0 1.0 14 Q92542,P62258,P61586 3 +Darpp 32 events 0.3177391853260441 0.0328015346698691 0.9738328543831204 1.0 1.0 10 P10644 1 +Ra biosynthesis pathway 0.2970058303538938 0.0315258647284519 0.974850165323096 1.0 1.0 5 O94788,Q8TC12,Q9BTZ2 3 +Mitotic g1 phase and g1 s transition 0.3517445290656868 0.0288355812048847 0.9769957229729164 1.0 1.0 75 Q99436,O00231,P31350,P30154,P28070,P33993,Q9NRF9,P31751,P49721,P49720,P51665,P06493,P20618,P49643,P00374,P31749,P15927,Q13616,P28074,P28072 20 +Pentose phosphate pathway 0.3037825059101703 0.0286328285718512 0.9771574293975964 1.0 1.0 7 P29401,Q96G03,P52209,P11413,O95336,P11908 6 +Signaling by the b cell receptor bcr 0.3819110061811459 0.0275256026042179 0.9780405196558914 1.0 1.0 46 O15111,Q9Y297,P28070,P49721,P62942,P49720,P20618,Q13616,P28074,P28072 10 +Unwinding of dna 0.3131538184877855 0.0245901593492496 0.9803818686294676 1.0 1.0 10 P33993,Q9BRT9,Q9BRX5 3 +Butyrate response factor 1 brf1 binds and destabilizes mrna 0.322537842694307 0.0220640230466113 0.982396884934842 1.0 1.0 13 P31749 1 +Formation of tc ner pre incision complex 0.3635908308101243 0.0220216188534659 0.982430710367214 1.0 1.0 29 Q13619,Q9UNP9,Q9UBW8,Q9BT78,Q9ULR0,Q9UNS2 6 +Transcriptional regulation by runx3 0.3792479009633618 0.0218354582495874 0.982579209330706 1.0 1.0 43 P49721,P28074,P28072 3 +Formation of tubulin folding intermediates by cct tric 0.3187333530630457 0.0214945687154021 0.9828511360006738 1.0 1.0 12 P50991,Q99832,P68371,P17987,Q13885,P49368,P40227,P78371,P04350,P48643,Q9BUF5 11 +Hiv transcription initiation 0.3238987806853678 0.0182468550434911 0.9854419239284432 1.0 1.0 14 Q00403 1 +Rho gtpases activate pkns 0.3330198134032324 0.011265678163048 0.9910114794575686 1.0 1.0 18 P60660,P62258,P63104,Q04917,P61586,P31946 6 +Transcriptional regulation by mecp2 0.3225889895248611 0.0095680867554987 0.9923658877831888 1.0 1.0 15 Q96ST3,Q14739,Q13555,Q9BZK7 4 +Regulation of runx2 expression and activity 0.3751438889264937 0.0081172532468011 0.9935234400815351 1.0 1.0 43 P49721,P28074,P28072 3 +Fceri mediated nf kb activation 0.3737618099823567 0.0018192130330816 0.9985484788087364 1.0 1.0 44 P25786,O15111,P61088,P28070,Q9Y297,P49721,P28074,P49720,P51665,P20618,Q99436,Q15008,Q13616,O14818,P28072,O00231 16 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5188f8cdafdec3f0e75e565dfc3def6c1afd327b --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Blood group systems biosynthesis", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chemokine receptors bind chemokines", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Chylomicron remodeling", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of signaling by nodal", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of o glycan biosynthesis", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APLP2", "APOB", "APOBEC3C", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHA", "BCKDK", "BCS1L", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPHL", "BPNT1", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRK1", "BSG", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CENPO", "CENPP", "CEP135", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLSPN", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG4", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ9", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFNB1", "EFTUD2", "EHD1", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1L", "FNTB", "FOXK1", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC1", "LRRC41", "LRRC8B", "LRRC8C", "LRSAM1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "M6PR", "MACO1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN2A1", "MAN2B1", "MANBA", "MAP2K1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL3", "MFGE8", "MFN1", "MFN2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINPP1", "MIOS", "MIPEP", "MLEC", "MMAB", "MMACHC", "MMADHC", "MMGT1", "MMS19", "MOCS1", "MOCS2", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1C", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCL", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NEU1", "NF1", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOCT", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDXK", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPLA8", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUS1", "PUS7", "PVR", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RALB", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RNASET2", "RNF20", "RNF25", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP8", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAMP1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35B2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMDT1", "SMG1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX3", "STX4", "STX5", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "TAB1", "TACC3", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126B", "TMEM30A", "TMEM63A", "TMEM87A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXN2", "TXNDC5", "TXNL1", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YEATS4", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AAMP", "AATF", "ABCB1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ACTR2", "ACVR1B", "ADAMTS1", "ADK", "AKT1", "AKT2", "ALDH1A2", "ALDH3A2", "ANAPC1", "ANAPC4", "ANAPC5", "ANKFY1", "ANXA1", "AP1M1", "AP3S1", "APLP2", "APOB", "APP", "APRT", "ARF4", "ARF5", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARL6IP5", "ARL8A", "ARPC4", "ARPC5", "ASAH1", "ASCC2", "ASNS", "ATP11C", "ATP13A2", "ATP1B1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BICD2", "BLMH", "BRD2", "BTRC", "C1QBP", "CADM1", "CALU", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CARM1", "CBFB", "CBX8", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CD2AP", "CD47", "CDC25C", "CDC37", "CDC42", "CDH2", "CDK1", "CDK2", "CDK4", "CDKN2A", "CHAC2", "CHD4", "CHMP3", "CHMP7", "CHPF2", "CHST12", "CHST14", "CHUK", "CLCN3", "CLCN6", "CLCN7", "COG4", "COG6", "COG8", "COLEC12", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS7A", "CPD", "CPT1A", "CREG1", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP2", "CTNNB1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL4A", "CUX1", "CXADR", "CYFIP1", "DAPK3", "DBNL", "DCTN1", "DCUN1D5", "DDRGK1", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHRS7B", "DNM2", "DNM3", "DNMT1", "DOCK7", "DPH2", "DSC3", "DSG2", "DSP", "DYNC2H1", "ECE1", "EEF2", "EHD1", 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0.0790607116166092 +Glucocorticoid receptor pathway 1 7 2.161574082915347 0.0306510209372152 2.0970873786407767 6.264563106796117 -0.0650526194059943 0.5956426022316084 1.5281473211321674 1.2542767820610936 0.7950472545634417 0.2902956743498178 0.2327120363884492 0.1541506060207377 0.0420348553288257 0.2000228109389489 0.4967295098899271 +Hostpathogen interaction of human coronaviruses interferon induction 1 5 2.1113155000426147 0.0347452026404899 2.594660194174758 6.33252427184466 -0.1132728664316908 0.583474774835163 1.8573576154624791 1.8495894157062076 0.8367707888568956 0.3067912858930513 1.0 1.0 1.0 1.0 0.3442759855295882 +Pathways of nucleic acid metabolism and innate immune sensing 0 5 2.0735781762270435 0.0381185037638458 1.6383495145631068 4.859223300970874 -0.1413162481479377 0.5139768956898912 1.3063642551600831 0.8152594313639914 0.9685327838493616 0.3029586620872576 0.0891620654695603 0.0573151884822011 0.1094892401774078 0.2559514735144251 0.4498304155532511 +Tgfbeta receptor signaling in skeletal dysplasias 1 5 2.0489762251825456 0.0404644397834006 1.6650485436893203 4.844660194174757 0.0189385850565167 0.5307098886145962 1.4479452289341006 0.8786273667377683 0.9337114291074744 0.3044153858417566 1.0 1.0 1.0 0.5885248237912099 0.5274882304980407 +Tgfbeta receptor signaling 1 5 2.0489762251825456 0.0404644397834006 1.6650485436893203 4.844660194174757 0.0189385850565167 0.5307098886145962 1.4479452289341006 0.8786273667377683 0.9337114291074744 0.3044153858417566 1.0 1.0 1.0 0.5676800659750835 0.4967295098899271 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..96d4a61deff710c2f5af4a0dc1ed5c1188d79448 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 610, + "title": "Average number of proteins per term", + "value": 11.068852459016393 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e5f8ece82dc4cf7e77413692696e34ac2ed3bb87 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..10676ceea2818db51f3ec0871b0ba2724617f6b9 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,215 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Inclusion body myositis 0.9634110357037432 2.824074583869808 0.0047417349296625 0.9449403258753172 0.1515591730660101 2 P05067 1 +Familial hyperlipidemia type 3 0.94924756565358 2.7657607685099466 0.0056790179678092 0.9690095129534302 0.1515591730660101 2 Q07954 1 +Glycosaminoglycan degradation 0.9515366430260098 2.7630934711534736 0.0057256367251683 0.9698833023743542 0.1515591730660101 7 P34059,P06865,P16278,P07686,P54802,P15586 6 +Degradation pathway of sphingolipids including diseases 0.9508428276415404 2.7601671812386672 0.0057771789123755 0.9708207702099176 0.1515591730660101 7 Q99519,P06280,P06865,P17900,P07686 5 +Vitamin d metabolism 0.9052325002079784 2.5776664765201502 0.0099469954458883 0.9977527462710432 0.1521410369707433 3 P04062 1 +Leptininsulin signaling overlap 0.8998528888874331 2.5548233944580683 0.0106241686931893 0.9985195585355248 0.1521410369707433 3 P31749 1 +Proteoglycan biosynthesis 0.8987739111443159 2.539650695512306 0.0110963230597342 0.998893542009624 0.1521410369707433 6 Q93063,Q8WVQ1,Q8NCH0,Q9NX62 4 +Extracellular vesiclemediated signaling in recipient cells 0.8893343010723908 2.502159171423656 0.0123438414252481 0.9994877010724608 0.1521410369707433 5 Q08431 1 +Mammary gland development pathway embryonic development stage 1 of 4 0.8866587957496986 2.49854085241396 0.0124705768008805 0.9995262742895494 0.1521410369707433 3 P23229,P31749 2 +Mirnas involvement in the immune response in sepsis 0.8769987400852743 2.4571011430729883 0.0140063246644948 0.9998166762255146 0.1525688936668184 3 Q16539 1 +Hedgehog signaling pathway wp4249 0.8705189064320946 2.417035504566288 0.0156474907700001 0.9999336412578164 0.1645684374086224 6 P98164 1 +Cancer immunotherapy by pd1 blockade 0.8650928520115062 2.4057563162963387 0.016139025998171 0.9999510697078604 0.1668611162522772 3 P04439 1 +Somatroph axis gh and its relationship to dietary restriction and aging 0.8565712261266549 2.368822445617539 0.0178448178692198 0.999983022701127 0.1700834203160019 3 P31749 1 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.8409712354218091 2.295826702902074 0.0216857919972861 0.999998444750424 0.1837268488658965 4 P31751,P31749 2 +Fibrin complement receptor 3 signaling pathway 0.835596221959848 2.277260782276531 0.0227706573770161 0.9999992095684788 0.1877040675672949 3 O15111,P31749 2 +S1p receptor signal transduction 0.8153806934387081 2.166129153496928 0.0303013189862804 0.9999999929457478 0.2280136923378209 8 Q13510,P31749 2 +Glucocorticoid receptor pathway 0.8136734401780477 2.161574082915347 0.0306510209372152 0.999999994338964 0.2280136923378209 7 Q08431 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.800607246908922 2.1113155000426147 0.0347452026404899 0.999999999571845 0.25231635250832 5 Q16539 1 +Tlr4 signaling and tolerance 0.7961562151659556 2.102595493893362 0.0355011441711465 0.9999999997345106 0.2547729169929343 3 O15111 1 +Il17 signaling pathway 0.7946693690215281 2.090088495859022 0.0366098508957217 0.9999999998683736 0.2571177944570249 4 P31749 1 +Metabolic pathway of ldl hdl and tg including diseases 0.7885275075834797 2.0684391917242357 0.0385987430792524 0.9999999999626872 0.2571177944570249 3 Q8WTV0 1 +Neuroinflammation 0.7868039925737345 2.0546975566145647 0.0399082261032648 0.9999999999837528 0.2571177944570249 4 O15111,Q16539 2 +Tgfbeta receptor signaling in skeletal dysplasias 0.7867928235500458 2.0489762251825456 0.0404644397834006 0.9999999999885908 0.2571177944570249 5 P40763 1 +Tgfbeta receptor signaling 0.7867928235500458 2.0489762251825456 0.0404644397834006 0.9999999999885908 0.2571177944570249 5 P40763 1 +Nodlike receptor nlr signaling pathway 0.7760401298317957 2.018911072042281 0.0434964632272365 0.999999999998345 0.2656875642110795 2 O15111 1 +Gpcrs class a rhodopsinlike 0.7745647683682539 2.012282218990047 0.0441901957071704 0.9999999999989369 0.2661437483140949 2 Q9Y3P9 1 +Autosomal recessive osteopetrosis pathways 0.7651224550014603 1.9697552028641632 0.0488664329329655 0.9999999999999466 0.2841911275134653 2 P51798 1 +Extracellular vesicles in the crosstalk of cardiac cells 0.7583357922690848 1.9390806622616492 0.0524915169841815 0.9999999999999948 0.2992507043023433 2 P40763 1 +Notch signaling 0.7489012940323595 1.876018759232138 0.0606527040210262 1.0 0.3333166617371715 5 Q92542 1 +Cell migration and invasion through p75ntr 0.748456430403937 1.8630775917046816 0.0624513504172767 1.0 0.3401368192369539 7 P31751,P31749 2 +Alzheimers disease and mirna effects 0.4880024520722088 1.8271835697406364 0.0676721733873129 1.0 0.3640313030948598 91 P31751,P28070,P49721,P05067,Q96IX5,P31749,Q9NSK0,Q96GC9,P17655,P28074,P28072,Q92542,Q07954 13 +Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition 0.7377940119175916 1.824794278531721 0.068032079594777 1.0 0.3640313030948598 5 P31749 1 +Signal transduction through il1r 0.7087217501173072 1.6896748993395594 0.0910901679062647 1.0 0.4292239375208036 5 Q16539 1 +Copper homeostasis 0.7064177426989293 1.6516277592533868 0.0986104575454347 1.0 0.4511400593101471 10 P35670,P05067,P31749 3 +Sphingolipid metabolism in senescence 0.7070194620194348 1.646820402657532 0.0995949664243274 1.0 0.4511400593101471 12 P16278,P04062,Q13510,Q16739 4 +Vitamin b12 metabolism 0.7042101969501297 1.6456177997223942 0.0998424721424096 1.0 0.4511400593101471 9 P98164,Q8WTV0 2 +Serotonin and anxiety 0.6916494541162578 1.6331832082357858 0.1024304704904677 1.0 0.4524141258111082 2 Q06787 1 +Ciliary landscape 0.3679522007286022 1.6311061904798685 0.1028679146924282 1.0 0.4524141258111082 110 Q8TD19,O60645,Q8TAG9,P16278,P14649,Q13576,Q9UNS2,Q9Y312,P06280,O43464,P33993,Q15555,P60660,P10619,Q96S59,Q9NWU2,P56545,P27105,Q5SW79,Q7L5Y9,O60841,P52565,P11234,P43034,Q9UBW8,Q9BT78,Q9UL25,Q9UN37 28 +7oxoc and 7betahc pathways 0.6985150537440035 1.618489055508578 0.1055572435730978 1.0 0.4524141258111082 9 Q9UBM7,P61916,O15118 3 +Neural crest differentiation 0.6909150575782088 1.5930818455005724 0.1111418314518082 1.0 0.4601195388751212 7 P05556,P56545,P19022 3 +Estrogen signaling pathway 0.6891680895296186 1.5908845497630324 0.1116355602516687 1.0 0.4601195388751212 6 Q16539,P31749 2 +Il4 signaling pathway 0.6937347551502596 1.5865878498472974 0.1126060210504826 1.0 0.4610045157100297 11 P40763,Q16539,P31749 3 +Il7 signaling pathway 0.6818426428543504 1.5442145185817588 0.1225363727662638 1.0 0.4911041073958491 8 P31749 1 +Vitamin d in inflammatory diseases 0.6743141689714587 1.535833587242163 0.1245791998353742 1.0 0.4911041073958491 4 Q16539 1 +Resistin as a regulator of inflammation 0.6779872120167929 1.5317107141528936 0.1255938373012335 1.0 0.4911041073958491 7 Q16539,P31751,P31749 3 +Relationship between inflammation cox2 and egfr 0.6625587893031895 1.4724337283237343 0.1409037907495181 1.0 0.5338590829640126 5 P31749 1 +Cancer immunotherapy by ctla4 blockade 0.656240778990856 1.467937392120882 0.1421212300550287 1.0 0.5351478415652318 2 Q06124 1 +Neural crest cell migration in cancer 0.6660613623044951 1.4577113817972955 0.1449201133837876 1.0 0.539032129049454 10 Q99523,P31751,P31749 3 +Tolllike receptor signaling pathway 0.6671153783696523 1.4493485028852622 0.1472402822695397 1.0 0.5443428617237531 13 P31751,Q16539,P31749 3 +Small cell lung cancer 0.663307580257487 1.4269752515844696 0.1535870282802611 1.0 0.5576671860176149 14 P23229,P05556,P31751,P06756,P31749 5 +Ebola virus infection in host 0.640101036962994 1.4198915258369855 0.155639263379675 1.0 0.5617748559858093 45 P23229,P10321,P07858,P06756,P46934,O15118,P31749,P61916,P01889,Q9UN37,P08069,Q08431,Q07021,P04439 14 +Serine metabolism 0.6457560465749993 1.3927278600436268 0.1637021004799237 1.0 0.5708892514665772 5 P00374 1 +Initiation of transcription and translation elongation at the hiv1 ltr 0.649700511602535 1.3902838648344744 0.1644426955100246 1.0 0.5708892514665772 8 P18615 1 +Statin inhibition of cholesterol production 0.6478794913122391 1.388024643301522 0.1651295412000535 1.0 0.5708892514665772 7 Q8WTV0,Q07954 2 +Splicing factor nova regulated synaptic proteins 0.6559128806725437 1.3792342536243427 0.1678225401090927 1.0 0.5708892514665772 18 Q9BY67,Q9UBB6,P19022,Q9NQX3,Q06481,Q9UNS2,Q92859 7 +Embryonic stem cell pluripotency pathways 0.6495188851481991 1.3630977421758212 0.1728517082710321 1.0 0.5784900064454656 13 P40763,P31751,P31749 3 +Synaptic signaling pathways associated with autism spectrum disorder 0.6389185766622453 1.3262814310654083 0.1847464951570328 1.0 0.5869550106551562 10 P21359,P31749 2 +Kisspeptinkisspeptin receptor system in the ovary 0.6302854238610524 1.2968762269153575 0.1946737774309568 1.0 0.5959780083653664 8 P31749 1 +Angiogenesis 0.6223346237251491 1.2900223583983956 0.1970428952750436 1.0 0.5959780083653664 4 P31749 1 +Thymic stromal lymphopoietin tslp signaling pathway 0.6332507189251558 1.2879669070013082 0.1977574831250961 1.0 0.5959780083653664 12 P40763,P31749 2 +Cardiac hypertrophic response 0.63036647767198 1.2738445894216992 0.2027184991171071 1.0 0.6061680610854675 12 P31751,Q16539,P31749 3 +Vitamin dsensitive calcium signaling in depression 0.6211121059305604 1.259686043698909 0.2077826419716006 1.0 0.6167680718935339 7 P00390,P11413,Q8NB78,P23634 4 +Nrp1triggered signaling pathways in pancreatic cancer 0.6260976933036522 1.2582935549619825 0.2082856111640458 1.0 0.6167680718935339 11 P31749 1 +Biomarkers for urea cycle disorders 0.6110947182059666 1.255492690871968 0.2092999597799998 1.0 0.6167776592550719 2 P17174 1 +Complement system 0.6225252102514194 1.240869648990132 0.2146539065220687 1.0 0.6172389329784114 11 P98164 1 +Follicle stimulating hormone fsh signaling pathway 0.6147215431698191 1.2218882463636227 0.221749890819261 1.0 0.6219465582675171 8 P31749 1 +Endochondral ossification 0.6165074594712563 1.2174589065297408 0.2234296623333798 1.0 0.6219465582675171 10 Q9Y496,P31749,Q9UHI8 3 +Endochondral ossification with skeletal dysplasias 0.6165074594712563 1.2174589065297408 0.2234296623333798 1.0 0.6219465582675171 10 Q9Y496,P31749,Q9UHI8 3 +Striated muscle contraction pathway 0.6086863685660948 1.2076437922341208 0.2271843068833057 1.0 0.6219465582675171 6 P09493,P67936 2 +Alzheimers disease 0.4434266104289108 1.2055016872030049 0.2280096870846812 1.0 0.6219465582675171 88 P28070,P49721,P05067,Q9NSK0,P31749,P17655,P28074,P28072,Q92542,Q07954 10 +Leukocyteintrinsic hippo pathway functions 0.6080341002910171 1.204524462595432 0.2283869328720063 1.0 0.6219465582675171 6 Q96GC9,Q16539 2 +Development of ureteric collection system 0.6042765678568132 1.1952328048296423 0.231996084881914 1.0 0.6261841229113608 5 O94813 1 +Sphingolipid pathway 0.610481374341789 1.188188674991328 0.2347590844653648 1.0 0.630850403188866 10 P04062,Q13510,Q16739 3 +Metabolism of spingolipids in er and golgi apparatus 0.6032528191711533 1.1816612621830975 0.2373401348398132 1.0 0.6322160797043059 6 P15291,Q10472 2 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.6122655390558697 1.170619876366225 0.2417516042560272 1.0 0.63279234789661 15 P05067 1 +Ras and bradykinin pathways in covid19 0.596939765878284 1.169444616608912 0.2422245427810847 1.0 0.63279234789661 4 Q99829,P61586 2 +Rac1pak1p38mmp2 pathway 0.6111253940938465 1.1608779926677792 0.245691519749891 1.0 0.63279234789661 16 P40763,P05556,Q16539,P31749 4 +Tnfrelated weak inducer of apoptosis tweak signaling pathway 0.6056959454450653 1.1587934010170196 0.246540407999821 1.0 0.63279234789661 11 P31751,Q16539,P31749 3 +Wnt signaling 0.6053159405385564 1.145763437370721 0.2518930474225485 1.0 0.6402281621989774 13 Q13555,Q8TAA9,P67870,P56545,P19784,P61586,P63000,O75116 8 +Allograft rejection 0.5979289283859894 1.120942921829441 0.2623121591438639 1.0 0.657760052557551 11 P10321,P01889,P08183,P04439 4 +Rala downstream regulated genes 0.5872101269406264 1.1139681052486825 0.2652928698670891 1.0 0.657760052557551 5 P16989,P11233 2 +Arrhythmogenic right ventricular cardiomyopathy 0.5968695086956988 1.0990752617912296 0.2717352392924326 1.0 0.657760052557551 14 P23229,P05556,P06756,P19022,O43707,P15924,P12814,Q14126 8 +Cannabinoid receptor signaling 0.5870675991240009 1.096354292939854 0.2729237581288695 1.0 0.657760052557551 7 P10644 1 +Epo receptor signaling 0.5879039175769537 1.0855208230719635 0.2776910461930666 1.0 0.657760052557551 9 P31749 1 +Vitamin a and carotenoid metabolism 0.5793048916586596 1.0763887017326357 0.2817534531699319 1.0 0.657760052557551 5 Q8WTV0 1 +Regulatory circuits of the stat3 signaling pathway 0.5842139892383444 1.0750253114340858 0.2823633962374008 1.0 0.657760052557551 8 P40763 1 +Genes controlling nephrogenesis 0.5801244511206854 1.071216511098035 0.2840720892548836 1.0 0.657760052557551 6 P05556,O94813 2 +Sars coronavirus and innate immunity 0.5697845972263237 1.0608648800532663 0.288751311786406 1.0 0.657760052557551 2 P42224 1 +Ddx1 as a regulatory component of the drosha microprocessor 0.5744174183277311 1.053185679363698 0.2922559005302578 1.0 0.6620866164512276 5 O60934 1 +Type i interferon induction and signaling during sarscov2 infection 0.5699527744982191 1.0514439663145865 0.2930547318718548 1.0 0.6620866164512276 3 P42224,P19525 2 +Alpha 6 beta 4 signaling pathway 0.576133739385091 1.0026563691443573 0.3160266881453113 1.0 0.6924383566365038 13 P23229,Q16539,P31749 3 +Head and neck squamous cell carcinoma 0.5719911145945833 0.9714020911119784 0.3313480876357688 1.0 0.7125523255504439 15 P08069,P31751,P31749 3 +Sulfation biotransformation reaction 0.5544963577853532 0.9687402117635108 0.3326748239213586 1.0 0.7125523255504439 4 P11413,O43252 2 +Micrornas in cardiomyocyte hypertrophy 0.5754241298792835 0.9623332752084168 0.3358822192066901 1.0 0.716392145860423 22 O15111,Q13144,P31751,Q16539,P31749,P40763,P08069 7 +Mirna biogenesis 0.550585415638715 0.9503766709908522 0.3419208935081874 1.0 0.7232394319215169 4 Q9UPY3 1 +Osteopontin signaling 0.55187462365364 0.9466139916361456 0.3438355116315439 1.0 0.7232394319215169 5 P06756 1 +Complement system in neuronal development and plasticity 0.5669083406597047 0.9464202321048164 0.3439342900541908 1.0 0.7232394319215169 15 P06756,Q08431,O43464,Q5KU26 4 +Mesodermal commitment pathway 0.5653055841166741 0.9243982073202948 0.3552790277362536 1.0 0.7350025433464287 18 O95071,Q93063,P56545,P10644,Q8IWS0,Q16527,Q16204,Q07021 8 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5528201454544048 0.9170986552003684 0.3590909457014055 1.0 0.737526858174604 9 P08069,P31749 2 +Ranklrank signaling pathway 0.5586552219150666 0.911577260916086 0.3619912971081942 1.0 0.739263185015135 14 Q16539,P31751,P31749 3 +Network map of sarscov2 signaling pathway 0.565363927160244 0.903484605112779 0.3662687551952699 1.0 0.7447464688970489 27 P07858,P31749,Q08380 3 +Il6 signaling pathway 0.5548526032216436 0.8991116165012576 0.3685932111732897 1.0 0.7449338310335542 13 P31749 1 +Physiological and pathological hypertrophy of the heart 0.5446816555888778 0.8946294858341612 0.3709851843434362 1.0 0.7449338310335542 7 P40763,Q16539 2 +Hepatitis b infection 0.5634257494303435 0.8941423877749344 0.3712457125150827 1.0 0.7449338310335542 26 P31751,Q16539,P31749,P31946,P40763,Q15904 6 +Intracellular trafficking proteins involved in cmt neuropathy 0.5476348055193079 0.8848538355185082 0.3762354692258274 1.0 0.7500118830972377 10 Q9NR77,O95140,P50570,O60333,Q6UWE0,P20338,P51149 7 +Transcription cofactors ski and skil protein partners 0.5379071717733437 0.8811107579029768 0.3782578750715664 1.0 0.7515873087741222 5 P21359 1 +3q29 copy number variation syndrome 0.5500542456626722 0.86978885076967 0.3844158055083513 1.0 0.7539988468170234 14 P02786 1 +1q211 copy number variation syndrome 0.5411390221680026 0.8616016052801427 0.3889067873410712 1.0 0.7575209481041933 9 Q9Y624,Q9UDY2 2 +Egfr tyrosine kinase inhibitor resistance 0.5531131484995757 0.8597315978652287 0.3899370126306831 1.0 0.7575209481041933 19 P21359,P40763,P31751,P31749 4 +Il2 signaling pathway 0.5351042777692014 0.8179231865171915 0.413401049709508 1.0 0.7855907798218065 11 P31749 1 +Neural crest cell migration during development 0.5281257993406941 0.8084668187755172 0.4188218999757269 1.0 0.7934203695192343 8 P31751,P31749 2 +Notch signaling pathway 0.5322583644827255 0.7905266631525986 0.4292202570559007 1.0 0.8031421987855811 13 Q92542,P31749 2 +Wnt signaling pathway 0.5164199326763299 0.7376870694126252 0.4607046315098619 1.0 0.8363982893482612 10 P31749 1 +Il3 signaling pathway 0.517369018527166 0.7270818162280859 0.4671758372547359 1.0 0.8400657587957753 12 P40763,P31749 2 +Hepatitis c and hepatocellular carcinoma 0.5181276983560944 0.7236248717448571 0.4692960676847129 1.0 0.8400657587957753 13 P40763,P31749 2 +Agerage pathway 0.5236138757320506 0.7199021242317337 0.4715852600390773 1.0 0.8400657587957753 18 O15111,P15311,Q16539,P31749,Q13464,P61586,P40763 7 +Proteasome degradation 0.5241838198427453 0.7150550875600091 0.4745750045027668 1.0 0.8409065864794402 42 P10321,P28070,P49721,P01889,P28074,P28072 6 +Netrinunc5b signaling pathway 0.5168911411757485 0.6987003203316837 0.4847393337209555 1.0 0.852463279606328 16 P30154,Q92859,Q16539,P31749 4 +Glioblastoma signaling pathways 0.5176645070960644 0.6773265070573973 0.4981988163799826 1.0 0.8682893656908269 21 P21359,P31751,P31749 3 +Regulation of apoptosis by parathyroid hormonerelated protein 0.4943758157928063 0.671344457575056 0.5020011192249891 1.0 0.8700820748090219 6 P31749 1 +Cholesterol biosynthesis with skeletal dysplasias 0.4958877025935432 0.6689827024675166 0.5035065121435816 1.0 0.8700820748090219 7 Q9UBM7,Q15392 2 +Nanoparticlemediated activation of receptor signaling 0.4945053122348383 0.6627585356012626 0.507485213624074 1.0 0.8744801703691669 7 Q16539 1 +Nephrotic syndrome 0.4851016347224212 0.586798202406419 0.5573392442423777 1.0 0.931443668459864 11 Q9Y5K6,Q9BT22,P52565,Q14108,O43707,O75844 6 +Oxysterols derived from cholesterol 0.4764661581971917 0.5826961685842614 0.5600978529340321 1.0 0.9318013540447214 7 Q9UBM7 1 +Breast cancer pathway 0.5001045272598096 0.5777053707376476 0.5634630525359983 1.0 0.9318013540447214 25 P08069,O60934,P31751,P31749 4 +Spinal cord injury 0.4957600097828428 0.5774086354725245 0.5636634420368889 1.0 0.9318013540447214 20 Q08722,P04083,P62942,P06493,O94813 5 +Chemokine signaling pathway 0.4968831084415059 0.573469264846392 0.566327003686419 1.0 0.9336742493208527 22 P40763,Q9UBI6,P31751,P31749 4 +Disruption of postsynaptic signaling by cnv 0.471108024602799 0.5416456995618888 0.5880626034213543 1.0 0.9616464472259102 9 Q13555,Q14168 2 +G protein signaling pathways 0.4818880538766003 0.530297754457261 0.595905503362941 1.0 0.9616464472259102 17 Q9UBI6,P10644,P29992 3 +Melanoma 0.4807055236170475 0.5249662089572805 0.5996066815476164 1.0 0.96506616291305 17 P21359,P31749 2 +Il1 signaling pathway 0.4747423589979584 0.5182981513716304 0.6042502625396771 1.0 0.9699806846031658 14 Q16539,P31749 2 +Map3k1 role in promoting and blocking gonadal determination 0.4526254063629083 0.5106872539607652 0.6095700672401765 1.0 0.9733972277919049 4 P61586 1 +Oncostatin m signaling pathway 0.476065696407049 0.5041694887120007 0.6141422792717748 1.0 0.9760481682188268 17 P40763,P31749 2 +Folate metabolism 0.4705606474667604 0.486194603440457 0.6268291971929623 1.0 0.9771468328120996 16 P00374,P04114,Q8WTV0,P34896 4 +Target of rapamycin tor signaling 0.4575302719510422 0.483550844436635 0.6287046674184242 1.0 0.9771468328120996 9 P31749 1 +Praderwilli and angelman syndrome 0.4501389631916508 0.4798379603171562 0.631342618269257 1.0 0.9771468328120996 6 Q7L576 1 +Primary focal segmental glomerulosclerosis fsgs 0.4716634820541139 0.4726567060420215 0.6364581189668617 1.0 0.9771468328120996 19 P06756,P19022,Q14108,P31749 4 +Epithelial to mesenchymal transition in colorectal cancer 0.4732702734492158 0.4690814684283309 0.6390114046258435 1.0 0.9771468328120996 21 Q8N3R9,P31751,Q16539,P19022,P31749,P15924 6 +Hypertrophy model 0.4364119209206292 0.4658167429753506 0.641346679581853 1.0 0.9771468328120996 2 P06730 1 +Vitamin d receptor pathway 0.4595479426185579 0.459764886889377 0.6456849892507122 1.0 0.9771468328120996 13 P11413,Q92783,P09493,P08183 4 +Purinergic signaling 0.4346414871643547 0.4587206995567638 0.6464347475070258 1.0 0.9771468328120996 2 P08754 1 +Glial cell differentiation 0.4337562702862337 0.4551852671900284 0.6489759587200989 1.0 0.9771468328120996 2 P26038 1 +Pkcgamma calcium signaling pathway in ataxia 0.4331699728163135 0.4315006011785909 0.6661044155849027 1.0 0.9958914056538988 4 P29992 1 +Ccl18 signaling pathway 0.4467824483669618 0.4220793862830962 0.6729670735378628 1.0 0.9983600124212046 11 P19022,Q96GC9 2 +Endometrial cancer 0.4523361234103528 0.4147564135763693 0.6783202300417313 1.0 0.9983600124212046 15 P31749 1 +Microtubule cytoskeleton regulation 0.4545446059996338 0.4105353238988793 0.6814132966758852 1.0 0.9990625901104634 17 P31749,P40763,Q13464,P06493 4 +Integrinmediated cell adhesion 0.4638037923438456 0.40841947519978 0.6829657378296119 1.0 0.9990625901104634 25 P23229,P31751,P06756,P31749,P17655,P07384 6 +15q112 copy number variation syndrome 0.4161421036289964 0.3760747034375256 0.7068613599494342 1.0 1.0 3 Q7L576 1 +Mecp2 and associated rett syndrome 0.4510256487863047 0.3665205118570125 0.7139767096400618 1.0 1.0 22 P21359,P31749,P67809 3 +Tcell receptor tcr signaling pathway 0.4425588406126239 0.3606934846036264 0.7183285958399852 1.0 1.0 17 O15111,Q16539,P31749 3 +Pathogenic escherichia coli infection 0.450168779297549 0.3578476323407814 0.7204573422663216 1.0 1.0 23 P05556,P15311,P60953,P63104,Q13885,Q13464,P61586,O75116,P04350,O15511,Q9BUF5 11 +Nucleotide metabolism 0.4359578010269657 0.3478157357629984 0.7279785712407854 1.0 1.0 15 P00374,P54098,P19623,Q7LG56 4 +Endoderm differentiation 0.4498243135776782 0.3471393142376868 0.7284866592887207 1.0 1.0 25 O95071,P56545,P05067,Q8IWS0,Q07021 5 +Hostpathogen interaction of human coronaviruses apoptosis 0.4132472017898582 0.3349398324163374 0.7376704738636284 1.0 1.0 6 P31749 1 +Lipid metabolism pathway 0.4288976650323793 0.3348601619315927 0.7377305750048966 1.0 1.0 13 P31751,P31749 2 +Nsp1 from sarscov2 inhibits translation initiation in the host cell 0.4256469242376064 0.3300904589944152 0.7413316122003872 1.0 1.0 12 P55884,O00303,P55010 3 +Fluoropyrimidine activity 0.4229198999056982 0.3196906702313781 0.749202833005514 1.0 1.0 12 Q92820 1 +Thyroid stimulating hormone tsh signaling pathway 0.4340001214118126 0.3016452031941839 0.7629225449226005 1.0 1.0 21 P08069,P40763,P31749 3 +16p112 proximal deletion syndrome 0.4377562986225169 0.2963988153653787 0.7669255299082081 1.0 1.0 25 Q6UXD5 1 +Androgen receptor signaling pathway 0.4366937030397705 0.2875797478162732 0.7736684491769457 1.0 1.0 26 Q86X55,P31749,O95251 3 +Omega9 fatty acid synthesis 0.3988183161004459 0.2831808591517683 0.7770382002656702 1.0 1.0 6 O60488,P33121,O00767,O95573,O95864 5 +Joubert syndrome 0.4205886011449684 0.2678336165685744 0.7888273934594507 1.0 1.0 18 Q8TD19,Q10713,P61586,Q7Z3E5,Q15154 5 +Interactome of polycomb repressive complex 2 prc2 0.390546528803548 0.2549580459086399 0.7987555030880693 1.0 1.0 6 Q9Y2W1,P55199,Q15022,Q9NYF8,Q09028 5 +Genes related to primary cilium development based on crispr 0.4079737869094301 0.249462378513729 0.803003138731007 1.0 1.0 14 Q9Y496,Q10713,Q8NCM8,Q86SX3,Q7Z3E5,Q9ULC3 6 +Parkinsons disease pathway 0.3964567459585998 0.240613466675571 0.8098547118902428 1.0 1.0 10 Q16539,P60604 2 +Modulators of tcr signaling and t cell activation 0.3983187581559045 0.2388800788058797 0.8111985732361697 1.0 1.0 11 O15111,P31749 2 +Sudden infant death syndrome sids susceptibility pathways 0.4279701248114952 0.2364106469326883 0.8131140352647126 1.0 1.0 30 P62258,Q9H0U9,P10644,P67809,P42892 5 +Prolactin signaling pathway 0.4164096939978228 0.2337594990983973 0.8151716935184097 1.0 1.0 21 P40763,Q16539,P31749 3 +Serotonin htr1 group and fos pathway 0.3838391013013664 0.2156434231931876 0.8292657052249717 1.0 1.0 8 Q16539 1 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.3928866594686024 0.2127861718980539 0.8314937499816395 1.0 1.0 12 P31749 1 +Sphingolipid metabolism overview 0.3876514503757082 0.2114282793663967 0.8325530917321946 1.0 1.0 10 Q13510,Q16739 2 +Sphingolipid metabolism integrated pathway 0.3876514503757082 0.2114282793663967 0.8325530917321946 1.0 1.0 10 Q13510,Q16739 2 +Malignant pleural mesothelioma 0.3943035249754907 0.2032839259873518 0.8389131184354282 1.0 1.0 69 Q08722,P23229,P05556,Q14574,O95816,P08195,Q16539,P31751,P06756,P19022,P31749,P19784,P31946,Q9UHI8,P23588,P08069 16 +Pdgf pathway 0.3921158045581437 0.2026402652076899 0.8394162157764786 1.0 1.0 13 P00403,O15111,P40763,P61586 4 +Mbdnf and probdnf regulation of gaba neurotransmission 0.3785649883348186 0.199024089075369 0.8422439011655445 1.0 1.0 8 P40763,P61586 2 +Integrated cancer pathway 0.3971522286824135 0.1977244691467809 0.8432606440439823 1.0 1.0 16 P53350,P31749 2 +Il5 signaling pathway 0.3848801883117456 0.1793452614847805 0.8576666094123806 1.0 1.0 13 P31749 1 +Interleukin11 signaling pathway 0.387171811209919 0.179260343244517 0.8577332839285794 1.0 1.0 14 P40763,P31749 2 +Interferon type i signaling pathways 0.3892221681508813 0.1786526446407819 0.8582104549492902 1.0 1.0 15 P40763,Q16539 2 +Tgfbeta signaling pathway 0.4172021207421712 0.172676106405611 0.8629060259702712 1.0 1.0 38 P05556,Q16539,Q9Y297,P05067,Q13464,P61586,P06493,Q96ST3,P31749,Q13616 10 +Translation factors 0.4144225990269073 0.167495986697713 0.8669798050752171 1.0 1.0 35 Q13144,P63241,P55010,Q9H074,Q15056,O75153,O75822,P23588,P55884,O60841,O00303 11 +Hepatocyte growth factor receptor signaling 0.3725794390064532 0.1647109926720776 0.8691714642622683 1.0 1.0 10 P40763 1 +Biomarkers for pyrimidine metabolism disorders 0.3625922251885406 0.1599515601125853 0.87291923224317 1.0 1.0 7 P31350,Q7LG56,Q9Y606 3 +Calcium regulation in cardiac cells 0.405040226013123 0.1566228650072006 0.8755420812741466 1.0 1.0 28 Q13555,P62258,P54709,P63104,P10644,P62942,Q04917,Q9UBI6,P31946,P23634,P29992 11 +Pancreatic adenocarcinoma pathway 0.3994027355331521 0.1511507537017447 0.8798567967121969 1.0 1.0 25 O15111,P31751,P60953,P11234,P31749,P61586,P11233,P40763,P10398 9 +Nonsmall cell lung cancer 0.3859409264634748 0.1478656419462244 0.882448803840068 1.0 1.0 18 P31751,P31749 2 +Hippo signaling regulation pathways 0.3872455004813122 0.1455672843631545 0.8842629961225557 1.0 1.0 19 P19022,P10644,P61586,P29992,P08069 5 +Thyroid hormones production and peripheral downstream signaling effects 0.3791333373449616 0.140256784952314 0.8884571073523868 1.0 1.0 16 Q16539,Q7LBC6 2 +Acute viral myocarditis 0.3808447631461863 0.1386986371640229 0.889688295076555 1.0 1.0 17 P78310,P31749 2 +Histone modifications 0.352532858994588 0.1325304964622691 0.8945647030775496 1.0 1.0 7 Q9H9B1,Q01105 2 +Tnfalpha signaling pathway 0.3848072774549829 0.1316990352024675 0.8952223486682003 1.0 1.0 20 P53350,O15111,P31749,Q9Y297 4 +P38 mapk signaling pathway 0.3486517346874765 0.1304694774577076 0.8961950011637096 1.0 1.0 6 Q16539 1 +Hippomerlin signaling dysregulation 0.3841575885887008 0.117786538928089 0.90623679567482 1.0 1.0 22 P23229,P06756,P19022,P10644,P08069 5 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.3523420983034265 0.1164116543860843 0.9073262993281296 1.0 1.0 9 P19784 1 +Metapathway biotransformation phase i and ii 0.3826672122699142 0.1131936633286975 0.9098770193120544 1.0 1.0 22 Q9NRB3,Q7LGA3,Q8NCH0 3 +Exrna mechanism of action and biogenesis 0.3329807395765398 0.1089602399731103 0.9132340264185016 1.0 1.0 4 Q9UPY3 1 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.3391928735615893 0.1070138871153941 0.914777962697008 1.0 1.0 6 O15111 1 +Lncrna in canonical wnt signaling and colorectal cancer 0.3557265463154881 0.1028925592636299 0.9180482432048768 1.0 1.0 12 Q00839,P48729,P35222,Q13363,P67870,Q9Y265,P56545,P19784,Q9UJX6,P61978,Q9HCK8 11 +Atm signaling in development and disease 0.3782456006016759 0.0998445207778538 0.9204677621516556 1.0 1.0 22 P11413,O60934,Q5VTR2,P06493 4 +Selenium micronutrient network 0.3536769102583756 0.0976311236254549 0.9222252094802852 1.0 1.0 12 Q8WTV0 1 +Chromosomal and microsatellite instability in colorectal cancer 0.3745259751158127 0.0889392632596633 0.9291301796090824 1.0 1.0 22 P11234,P31751,P31749,P61586 4 +Corticotropinreleasing hormone signaling pathway 0.3711809209879797 0.0852373344437571 0.9320727099759564 1.0 1.0 21 P42892,P31749 2 +Ampactivated protein kinase ampk signaling 0.3554869220704415 0.0813882740583424 0.9351331741197436 1.0 1.0 15 P31749 1 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3311059367587284 0.0735081615742103 0.9414017496502664 1.0 1.0 8 Q16539 1 +Interleukin1 il1 structural pathway 0.3360909871028218 0.0700335677352026 0.9441669420311612 1.0 1.0 10 Q16539 1 +Pentose phosphate pathway in senescent cells 0.3036030714707688 0.0422554177065687 0.9662950850351202 1.0 1.0 5 O95336,P29401,P11413,P04637 4 +Pentose phosphate metabolism 0.303603071470767 0.0422554177065657 0.9662950850351226 1.0 1.0 5 P29401,P11413,O95336,P52209 4 +Ras signaling 0.3724129737370105 0.0375302853502078 0.9700621929330376 1.0 1.0 31 P21359,O15111,P31751,P11234,P31749,P61586,Q9UBI6,P08069 8 +G13 signaling pathway 0.3346420910152483 0.0268487778756408 0.9785803481047284 1.0 1.0 16 P60953,P48426,Q7L576,P46940,Q13464,P61586,Q13576,O60610,O75116 9 +Influence of laminopathies on wnt signaling 0.3065891712448068 0.0266052833437346 0.978774559253678 1.0 1.0 8 Q9UPY3 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.3247106575780378 0.0261754466039117 0.9791173999426884 1.0 1.0 13 P55209,Q9UPY3 2 +Nanomaterial induced apoptosis 0.2988838345453936 0.0208632231797531 0.9833547638850264 1.0 1.0 7 O95831 1 +Pi3kakt signaling pathway 0.376598826258135 0.0148337635886329 0.9881648030928124 1.0 1.0 42 P23229,P05556,O15111,P30154,P31751,P06756,P31749,Q9UBI6,P23588,P08069 10 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.2886430251537418 0.0061318499934308 0.99510752222029 1.0 1.0 7 P06756 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..37cc5803fb728022463c97f185e2f3d364ff72a8 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgf23 signaling in hypophosphatemic rickets and related disorders", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peptide gpcrs", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ABHD16A", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APLP2", "APMAP", "APOB", "APP", "APPL1", "APRT", "ARAF", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL5B", "ARL8B", "ARMC9", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATIC", "ATP11C", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKB", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCKDHA", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCS1L", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHMP5", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLCN7", "CLIC1", "CLPTM1L", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ9", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPT1A", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUX1", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAPK3", "DARS", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPF2", "DPM1", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAVL1", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "ENPP1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERI1", "ESD", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNS", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F2", "GTF2H4", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOXD11", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HTRA2", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF20B", "KIF22", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPCAT3", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LUC7L", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "METTL3", "MFGE8", "MFN2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MMACHC", "MMADHC", "MOCS1", "MOCS2", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NEU1", "NF1", "NFATC2IP", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NME6", "NOCT", "NONO", "NOP2", "NPC1", "NPC2", "NR2F1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PATZ1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PDSS1", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMAIP1", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA8", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PVR", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RALA", "RALB", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RIF1", "RING1", "RMND5A", "RNASEH2A", "RNASET2", "RNF20", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDF2L1", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIN3A", "SIRT2", "SKP1", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35B2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD5", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX3", "STX4", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCP1", "TECR", "TEDC1", "TELO2", "TERF2", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", 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"ZMPSTE24", "ZMYM3", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["AAR2", "ABCB1", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAMTS1", "AIFM1", "AKT1", "AKT2", "ALG1", "ANAPC2", "ANXA1", "APLP2", "APOB", "APP", "ARAF", "ARHGDIA", "ARMC9", "ARPC5", "ASAH1", "ATP1B3", "ATP2B4", "ATP6AP1", "ATP7B", "B4GALT1", "BAG2", "BCLAF1", "BTRC", "C1QBP", "CADM1", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CARM1", "CCDC6", "CD2AP", "CD47", "CDC42", "CDH2", "CDK1", "CEP170", "CHD8", "CHST12", "CHST14", "CHUK", "CLCN7", "CLUH", "COLEC12", "COPS3", "COPS4", "COPS7A", "COX2", "CPNE1", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CTBP1", "CTBP2", "CTNNB1", "CTSA", "CTSB", "CUL1", "CXADR", "CYFIP1", "DHCR24", "DHCR7", "DHFR", "DIAPH1", "DICER1", "DNM2", "DSC3", "DSG2", "DSP", "DYNC2H1", "ECE1", "EHMT1", "EIF2AK2", "EIF2B5", "EIF3B", "EIF3F", "EIF3J", "EIF4B", "EIF4E", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELL", "EXOC3", "EXOC6", "EXT2", "EZR", "F11R", "FADS2", "FKBP1A", "FMR1", "G6PD", "GALNS", "GALNT1", 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a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..aeeec41db469d50897f9386d0ced4d232c63309f --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +vesicles 42 182 2.7681069198358284 0.0056382954885552 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 0.0172293450373959 0.0065057262929439 0.0001102500366999 0.0002842689002867 6.573490810656996e-07 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..578b61e236cdf61903b6cb8a0ffa5bd17dcb8289 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 100.05882352941177 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d57bb9ee185d51f962bd6c3e0680201cf716b746 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..99c4abf2ea4846c7720e2934807e6c4411160a12 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +vesicles 0.4286217454355812 2.7681069198358284 0.0056382954885552 0.091647047341927 0.0958510233054386 182 O15126,Q13277,Q10713,P30825,Q9UJU6,Q15392,Q06481,O75787,O43752,P08069,P02786,Q9H2J7,Q8IZA0,O15027,Q6NT16,Q9Y3E7,Q8NBN3,Q92783,Q15904,P11413,Q93050,P31751,P61421,P13473,P11279,Q96BM9,Q8IXU6,Q86Y82,O00264,O15400,Q5VW38,P61160,Q15125,P48449,P04439,P41440,P31749,P51798,Q9NUM4,Q8IY95,Q9UN37,Q9Y3P9 42 +membrane 0.4778923734783134 1.661228983250743 0.0966674666966236 0.8224134476643157 0.6247564587740335 90 O15126,Q13277,P30825,Q9NVZ3,Q96N67,Q9UJU6,P14649,P08069,P02786,P42356,P15311,Q13308,Q9UNF0,Q8TBX8,Q13464,P42566,P12814,O43293,Q9Y6I3,Q8NC96,Q5T0N5,P31751,Q68EM7,Q9ULC3,Q16181,P61160,P04439,P41440,P19022,P31749,Q9NUM4,Q9UQB8 32 +cell_contact 0.5395743238502985 0.7681587934271653 0.44239285106908 0.9999512940899168 1.0 30 Q9UDY2,P62258,Q9NVZ3,Q96N67,Q9UJU6,P19022,Q13464,P31749,P42566,Q04917,Q9UQB8,Q9ULC3 12 +golgi 0.4365942359012879 0.3610749885559089 0.7180433900081689 0.999999999550118 1.0 61 O15126,Q8IZA0,Q9Y6B6,Q9Y487,Q8IXU6,Q13190,Q8NBN3,Q8TAD4,Q15904,Q5VW38 10 +cytoskeleton 0.412042887481233 0.1536385609863849 0.8778947306260976 0.9999999999999996 1.0 37 P35580,P60660,Q9UJX5,P60953,O43707,P06493,P12814,O43293,P14649,Q16181,P35579,Q5SW79,O00139,Q15019,P14635 15 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..69bb4ae3cae1623b2b731574d5cccdb3b7b926fe --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT1", "AKT1S1", "AKT2", "ALDH9A1", "ANAPC16", "ANAPC2", "ANAPC4", "ANXA11", "AP2B1", "AP2S1", "APLP2", "APPL1", "ARAF", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BET1", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C12orf57", "C19orf53", "C1orf123", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP2", "CASP3", "CASP7", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2BP2", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2A", "CEP135", "CEP170", "CEP250", "CETN2", "CHEK1", "CHEK2", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLCN7", "CLINT1", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DAPK3", "DBNL", "DCP1A", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DEGS1", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2LI1", "DYNLL1", "DYNLL2", "EBNA1BP2", "EBP", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMG1", "ENO1", "ENY2", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FANCA", "FARP1", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FNBP1L", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPR107", "GRB2", "GSK3A", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPBP1", "HSPH1", "HUS1", "IDI1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF3", "ILK", "INPP4A", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "KDSR", "KEAP1", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMNA", "LMNB1", "LPCAT1", "LSM14A", "LSM14B", "LSS", "LTV1", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED17", "MED20", "MED24", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO6", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PAK4", "PARP1", "PATZ1", "PBK", "PCNA", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHGDH", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R2", "PIN4", "PIP4K2A", "PIP4K2C", "PKM", "PKMYT1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "PPM1G", "PRKACA", "PRKCD", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBBP4", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM8A", "RBMX", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RHOA", "RHOG", "RING1", "RIOK2", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP1", "SCD", "SCFD1", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A1", "SLC30A5", "SLC35F2", "SLC4A2", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX9", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIP1", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX6", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TARDBP", "TCOF1", "TERF2", "TFRC", "TGFBRAP1", "TIA1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOLLIP", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM24", "TRIM28", "TRIM33", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TTK", "TUBB4B", "TUBG1", "TWISTNB", "U2AF2", "U2SURP", "UBA1", "UBA5", "UBE2M", "UBTF", "UFC1", "UGDH", "UPF1", "USP10", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS18", "VPS25", "VPS29", "VPS33A", "VPS35", "VPS36", "VPS4A", "WAPL", "WASF2", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO4", "XPO5", "XPOT", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["ACTN1", "ACTN4", "ACTR2", "AKT1", "AKT2", "ANAPC4", "APLP2", "ARHGAP17", "ARL8A", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "BAIAP2", "CCNB1", "CDC42", "CDH2", "CDK1", "CEP170", "CHMP3", "CLCN7", "DAPK3", "DBNL", "DHCR24", "DOCK7", "EBP", "EPN1", "EPS15", "EZR", "FNBP1L", "G6PD", "GPR107", "HLA-A", "IGF1R", "KIAA0319L", "KIF2A", "LAMP1", "LAMP2", "LSS", "MYH10", "MYH9", "MYL6", "MYL6B", "NECAP1", "NECAP2", "PACSIN2", "PGRMC1", "PI4KA", "PIP4K2C", "PMPCA", "PTK7", "RAB23", "RABGAP1", "ROCK1", "SAR1B", "SCAMP1", "SEC16A", "SEPT2", "SEPT7", "SLC18B1", "SLC19A1", "SLC30A5", "SLC35F2", "SLC6A15", "SLC7A1", "STAM", "STX12", "STX3", "STX5", "STX6", "STX7", "TFRC", "TJP2", "TMEM106B", "TMEM192", "TMEM87A", 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sha256:7360da3696f09ab3dee48e708ae4912bd503a017e37553303212004f9559cf40 +size 91842 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..48a438c88ca0ae3f3c1533eda3179a2ba43acdf7 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +glycosidase 3 5 2.826719015216435 0.004702757276974 2.349514563106796 4.621359223300971 -0.2307336370526829 0.2597902373581335 1.0699672244692364 0.6012366681705257 1.6034021241460206 0.2766391836749902 1.1479921506057917e-07 3.8308667598491466e-06 2.747580602519606e-07 1.1289574774720508e-05 0.0001708540892308 +cytoskeletal protein 1 5 2.152688401197188 0.0313431756696589 2.237864077669903 5.473300970873787 0.1919229793698151 0.5692249777284041 1.7367314745045732 1.119884606008921 0.8396864574135288 0.2999141192799986 1.0 1.0 0.1432798584585485 0.0565188023636715 0.1807018090276839 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e9b6631056dc8cf78111036e8bb84b537fa80fbb --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 164, + "title": "Average number of proteins per term", + "value": 14.067073170731707 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..78dbef37889a47d08f481da726ca26eeb75a58a5 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed6417cf8f3cdb833ab3d7d82beae4a7fc04d74e --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,47 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +glycosidase 0.9660575759512202 2.826719015216435 0.004702757276974 0.5384068507161215 0.1103832849827305 5 P06865,P04066,Q9BTY2 3 +galactosidase 0.9583948067276448 2.803468358854402 0.0050556192692816 0.5644843346753615 0.1103832849827305 2 P06280 1 +G-protein coupled receptor 0.9457341080322434 2.7446460510584285 0.0060576192978327 0.6308199233611226 0.1103832849827305 4 Q8NBN3,Q9NPR9 2 +major histocompatibility complex protein 0.9347697756788644 2.7020121015996605 0.0068921253812443 0.6783276077702818 0.1130308562524081 3 P10321,P01889 2 +cadherin 0.8937426210153407 2.528804101724171 0.0114451888686133 0.8486007686674737 0.144107570551943 3 Q14126,Q14574 2 +integrin 0.8866587957497039 2.4985408524139854 0.0124705768008797 0.8722951923940723 0.144107570551943 3 P06756,P23229 2 +apolipoprotein 0.8629945126833752 2.3966760710357877 0.0165445426339174 0.935170910464929 0.144107570551943 3 Q07954 1 +viral or transposable element protein 0.8207736623647421 2.2119977236454105 0.0269668222207184 0.9887037472829744 0.1579485301499223 3 Q9NUD5 1 +cytoskeletal protein 0.8098240682328031 2.152688401197188 0.0313431756696589 0.994606501441326 0.1638039097269548 5 P27105 1 +primase 0.7630569489524931 1.9604289896098843 0.0499456702560665 0.9997757438243464 0.2047772480498728 2 P49643 1 +protease inhibitor 0.7602553344382486 1.913466250069161 0.0556883901539215 0.9999170313580464 0.2227535606156863 8 P05067 1 +ion channel 0.7376874941896433 1.8129845951335992 0.0698341973278364 0.9999930192759204 0.266344380506167 7 Q9C0H2,P51797,P51790 3 +amino acid transporter 0.7192339395618473 1.7456649512228897 0.0808691887448427 0.9999990139901042 0.2947232656478712 4 O75915,P30825 2 +cysteine protease 0.7128764955047034 1.6742825817618028 0.0940750760913471 0.9999999081409092 0.3213662015507129 26 P07858,Q92820,Q99538,Q13510,P17655,P53634 6 +tubulin 0.6943209065199312 1.6151929971341814 0.1062689066034392 0.9999999900476354 0.3351557823646929 6 P23258,Q13885,Q9BUF5 3 +serine protease 0.6869586593317188 1.5360375832706603 0.1245291629663496 0.9999999996629952 0.3646925486871668 17 O14773,P10619,Q9HB40,Q9H3G5 4 +G-protein modulator 0.6687333923826495 1.509566382873204 0.1311541047100171 0.9999999999030358 0.377355669691979 4 P52565,P31150,Q9H2M9 3 +transcription cofactor 0.6699737401717689 1.4766006190585013 0.1397827256897992 0.9999999999811314 0.3888400371465473 10 P51858,O14777,Q7Z4V5 3 +phospholipase 0.6612515804712944 1.4457260826421556 0.148254045641708 0.9999999999962772 0.4052277247540021 8 Q8NHP8 1 +metalloprotease 0.6469502191483113 1.3352352812734871 0.1817993529662023 0.9999999999999948 0.4721067555116424 28 Q6P179,Q9UIQ6,Q9BYT8,P22695,P42892,O75844,P55786,Q9UHI8,Q9NZ08,P02786 10 +dehydratase 0.6215742576551875 1.29547273605707 0.1951572006221176 0.9999999999999996 0.4776982224183178 3 P61457 1 +SNARE protein 0.6170938820789671 1.1906335858184376 0.2337974607154649 1.0 0.5477540508190892 16 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +transmembrane signal receptor 0.5751841330624248 1.010395513871599 0.3123058363261963 1.0 0.6566430404807205 11 Q15375,Q96GC9,O75787,O00264,P08069,Q99720,O15173 7 +hydrolase 0.5492703207826943 0.8247566745310325 0.4095097484843393 1.0 0.7491614489862842 24 Q99519,Q9HB07,P34059,P15586,O43598 5 +membrane trafficking regulatory protein 0.5460706647884804 0.8139157050114046 0.4156932430350724 1.0 0.7491614489862842 22 P13473,P11279,O43731,Q14108,Q8WTV0 5 +actin binding motor protein 0.5066122441959808 0.7176451510227931 0.4729761104983474 1.0 0.8165061275971471 7 P09493 1 +mRNA capping factor 0.4896694214875872 0.6813439488168779 0.4956538805613446 1.0 0.8294615960414339 3 Q9NPI6,O60942 2 +extracellular matrix protein 0.4819952774498129 0.6473938731668479 0.5173770602117276 1.0 0.8570690694416497 3 Q9UFC0,P07942 2 +glycosyltransferase 0.5127746127080892 0.6345884279741679 0.5256968773891777 1.0 0.8570801034568893 27 O60512,Q16739,Q86SF2,Q93063,Q9P2E5,P15291,Q10472,Q10471 8 +kinase 0.5097791788324388 0.6313129558053521 0.5278359173728404 1.0 0.8570801034568893 23 Q13572,Q8TBX8,Q9HBU6 3 +Hsp90 family chaperone 0.4511366991437895 0.5044929690522713 0.6139150017144583 1.0 0.942268532502902 4 P08238,Q12931,P07900 3 +membrane traffic protein 0.4361302890879353 0.5017130528854612 0.6158693814230045 1.0 0.942268532502902 70 O60645,Q12907,Q99523,Q9UQ16,Q9H4M9,Q8TAG9,O43493,P40855,Q9H223,P20645,A6NIH7,Q9BRG1,Q5JRA6,P11717,Q6NUK4 15 +calmodulin-related 0.4694583866884229 0.4951159127033366 0.620518301892155 1.0 0.942268532502902 14 O43852,P80303,Q9BRK5 3 +transferase 0.4811573580603413 0.4706187642593348 0.6379130053416975 1.0 0.9597957144590678 32 Q7LGA3,O43505,Q11206,Q8NCH0 4 +G-protein 0.4384208435770068 0.4320696237287858 0.6656908113718971 1.0 0.9780764759802278 6 Q9NTK5,P18085,P84085 3 +actin or actin-binding cytoskeletal protein 0.4275062244944713 0.2703990967971698 0.7868532348817137 1.0 1.0 22 P60660,P15311,Q9UNF0,Q16527,P14649,Q96HC4,O15511 7 +nucleotide phosphatase 0.3947752556523692 0.2692486058662892 0.7877383787258312 1.0 1.0 6 Q8WVQ1 1 +mitochondrial carrier protein 0.3964744232088582 0.2574328023757368 0.7968446833059173 1.0 1.0 8 Q9Y6C9 1 +DNA-directed DNA polymerase 0.3865897368367048 0.2418539228979422 0.8088933544832013 1.0 1.0 6 P40937,P40938,P54098,P56282 4 +heterotrimeric G-protein 0.3829141744104406 0.2043917581242276 0.838047370308088 1.0 1.0 9 Q9UBI6 1 +protein modifying enzyme 0.4120127795626517 0.1864767874137111 0.8520708805448036 1.0 1.0 27 O00462,O15460,P50897,Q9UMR5,Q86X55 5 +protease 0.409731415446193 0.1375871506411052 0.8905667112434272 1.0 1.0 45 Q9UJ14,P28070,P49721,P49720,O75976,Q9UNS2,P28074,P28072 8 +ATP synthase 0.3707158601068019 0.0780802509977772 0.937764216648134 1.0 1.0 22 Q15904,Q96IX5,P61421,Q93050 4 +non-motor microtubule binding protein 0.3604129960149123 0.0681970474459769 0.9456287772983032 1.0 1.0 19 Q15555,Q9UN37,Q9UH99 3 +nucleic acid metabolism protein 0.2981989961618059 0.0405457974753867 0.9676579959342702 1.0 1.0 4 Q9Y2W1,P49750,Q9NYF8 3 +primary active transporter 0.3686278695081845 0.0311607905948665 0.9751413092905604 1.0 1.0 30 Q9H2J7,Q6P4A7,P35670,O60888 4 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7e1dd39ec2ba5ab03f7e65bf6e0a897656b7d8cf --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "membrane-bound signaling molecule", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "serine/threonine protein kinase receptor", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOB", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP35", "ARHGDIA", "ARID3B", "ARIH1", "ARL1", "ARL5B", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BET1", "BLMH", "BLVRA", "BOP1", "BPHL", "BPNT1", "BRCA1", "BRD1", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC28A", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD3EAP", "CD47", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CENPB", "CEP135", "CEP170", "CEP250", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC22", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENY2", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GGT7", "GID8", "GINS2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIC2", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HOXD11", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "KLC1", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3HYPDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8B", "LRRC8C", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MACO1", "MAGED1", "MAGED2", "MAGT1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFSD3", "MGEA5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCOA5", "ND1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NENF", "NEU1", "NF1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOC4L", "NOCT", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD6B", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD18", "RAD23B", "RAE1", "RAI1", "RALA", "RALB", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM26", "RBM27", "RBM34", "RBM4", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RIOK2", "RNASEH2A", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC35B2", "SLC39A7", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK11IP", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM38B", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", 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0000000000000000000000000000000000000000..cd1f26529530a07b672b94e427c42345c656e942 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c38c079b382527d10d572777dec7f714ee014d03023342aaaaa9814cbed0f3e3 +size 138894 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..92dd91005774c792797247e96a7605b25ebc2e29 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef6c10efc02801ad9d02a3a3333ccbebecb8e6a7204f20a394b5ffe345363ef6 +size 469976 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..898a52b6208bdf84b1791fcbe88a1b4af21a5f89 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Hydrolase 15 110 3.519025240853524 0.0004331354968338 21.012135922330096 100.5121359223301 -0.2860490073063528 0.5453469972424007 9.92849915333812 10.239716522783334 1.1334611818491105 0.3594139124058108 7.760888479205423e-05 0.0135853045980349 3.8983824458866855e-06 0.0019884852111238 0.0261145397506748 +Protease 18 116 3.4965689957747914 0.0004712826022323 23.87864077669903 112.97330097087378 0.5565894930811873 0.44121745363286 8.615285022365173 8.917462185063522 1.4311973593718734 0.3778605174872721 3.215952879344939e-09 7.719523531021813e-06 9.46204946351118e-09 1.7412026828224343e-05 0.0012456545718245 +Phosphatase inhibitor 5 6 2.172773212648506 0.0297973903715447 2.728155339805826 6.172330097087379 0.9635556310357324 0.3115567860102488 1.3049136024465862 0.9562829575598468 1.0731560672377305 0.3073869469134278 1.0 1.0 1.0 0.0442367692127036 0.0003671727016274 +Growth factor 2 5 2.122683777976589 0.0337803592696044 1.4587378640776698 4.927184466019417 0.569518613320005 0.5011207143101012 1.240789898436257 0.6715717218754621 0.8148940327825237 0.3038203600724809 1.0 1.0 1.0 0.3258327648280404 0.0397387250697101 +Cell adhesion 2 6 2.089198604953977 0.036689848969065 2.216019417475728 4.70873786407767 -0.4730897676645991 0.4035868525167316 1.4344701263227069 1.4082356099838216 1.1216812207119993 0.3050756247290374 0.0050782941261834 0.066549445548378 0.0077184558590264 0.0042425564235442 0.0277461310389573 +Transporter 40 209 2.033648294953958 0.0419870687849441 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 0.0832804888457488 0.089538527350807 0.0446398896921955 0.0038749428200107 0.0001006677011835 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..469ba8529e2b69d776d12627f698cd2aff01c64d --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 2141, + "title": "Average number of proteins per term", + "value": 3.1303129378794954 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ec3797257ccf092822c27715dd24c70a20774f85 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..497868d8eaf967167e2d95cd9a56a5ea98a8c9e9 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,73 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hydrolase 0.5198464909935097 3.519025240853524 0.0004331354968338 0.6044760705628639 0.0527878405654427 110 Q8NCC3,O00462,Q99519,P34059,P06865,P11117,P07686,Q9NX62,P16278,P50897,P15586,Q9UMR5,Q08431,Q9HAT2,P10253 15 +Protease 0.5167257776519915 3.4965689957747914 0.0004712826022323 0.6355091723196956 0.0527878405654427 116 Q8TCT8,Q6P179,P07858,Q92820,P10619,Q8NHP8,Q99538,Q9UIQ6,Q13510,Q9HB40,P42892,O14773,Q5BJF2,Q9UHI8,Q9H3G5,P42785,P53634,P02786 18 +Galactosidase 0.9583948067276468 2.8034683588544156 0.0050556192692814 0.9999806251483802 0.0527878405654427 2 O00462 1 +Glycosidase 0.9523847554743224 2.7753076623988795 0.0055149509132699 0.999992791062834 0.0527878405654427 3 P06865 1 +Cadherin 0.945706698141039 2.7511184974004985 0.0059392154752901 0.9999971086054624 0.0527878405654427 2 Q14574 1 +AKT family 0.942165830628501 2.7364505867759807 0.0062105921497752 0.9999983884921998 0.0527878405654427 2 P31749 1 +Cu+-ATPases 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.9999999688295446 0.0529749693938309 2 P35670 1 +Chloride channel family 0.8919716646989307 2.521248189040821 0.0116939339469988 0.999999999988449 0.0566038321470551 3 P51797,P51790 2 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8852168781351337 2.4969794597023713 0.0125256211796576 0.9999999999980952 0.0580462228260756 2 P08195 1 +SLC30 zinc transporter family 0.8191206845677113 2.2105223591058833 0.0270689305088538 1.0 0.079717441842443 2 Q8TAD4 1 +Phosphatase inhibitor 0.8153618906942401 2.172773212648506 0.0297973903715447 1.0 0.0842750499147651 6 Q01105,Q9H0U9,Q9BTT0,P55209,Q99733 5 +Growth factor 0.8031358968471993 2.122683777976589 0.0337803592696044 1.0 0.0893989483266045 5 P51858,Q7Z4V5 2 +Cell adhesion 0.7968157833669329 2.089198604953977 0.036689848969065 1.0 0.0944146233687117 6 P43121,Q14574 2 +Transporter 0.3724709542868819 2.033648294953958 0.0419870687849441 1.0 0.1019209912342012 209 O60645,Q13277,Q99523,P08195,Q9UBX3,P30825,Q8TAG9,P17900,Q04656,Q13190,Q5SQN1,P08183,O43752,Q99805,Q9H2J7,Q12907,Q6NT16,O43493,Q92544,Q14444,Q8NB49,Q15070,Q9HD45,Q93050,P61421,P13473,P11279,O43731,Q9Y487,Q7L0J3,Q9NWU2,Q8IXU6,Q86Y82,Q8TAD4,O15400,Q6NUK4,P35670,O00560,Q92572,Q9Y6C9 40 +Lysine demethylase 0.7564605007268603 1.9235847386224 0.0544066555148021 1.0 0.117748497432417 3 Q8NB78 1 +CK2 family 0.7524343464148613 1.9123345989601104 0.0558332907228831 1.0 0.1189926011822091 2 P19784 1 +ROCK subfamily 0.7459427559752159 1.8828370672236316 0.0597224520026844 1.0 0.1245236639070953 2 Q13464 1 +Protease inhibitor 0.7531681093946913 1.8699883460988709 0.0614854362144616 1.0 0.1265929304130692 11 Q06481,P05067 2 +Ion channel 0.7155479334537841 1.6994734746950697 0.0892300082883306 1.0 0.1602982191996831 9 Q9C0H2,P51797,P51790 3 +Aspartic protease 0.7080360392464968 1.693648283267385 0.0903321372809053 1.0 0.1617066102996809 4 Q8TCT8 1 +Na+/K+-ATPases 0.7046095612082809 1.6852564126603606 0.0919391113053431 1.0 0.1634126730016958 3 P54709 1 +Lipase 0.7023678283100468 1.653076064830696 0.098315383902368 1.0 0.1698881597294028 6 Q8NCC3 1 +Tubulin 0.6943209065199312 1.6151929971341814 0.1062689066034392 1.0 0.1791509677464278 6 P23258,Q13885,Q9BUF5 3 +Phosphatase modulator 0.6890588083566238 1.5786060194187794 0.1144264531219947 1.0 0.1891791784820005 8 Q01105,Q9H0U9,Q9BTT0,P55209,Q99733 5 +TK group 0.6723071989978764 1.5263917010837167 0.1269123431987426 1.0 0.2023226558365659 4 Q15375 1 +Protein methyltransferase 0.6737566256425029 1.511580264545581 0.1306406754292663 1.0 0.2059658955037255 7 Q86X55,O96028 2 +SNARE protein 0.6569139929562228 1.3920483511529655 0.1639077568490154 1.0 0.2390507543690341 15 Q13277,O15400,Q13190,Q5SQN1,O43752 5 +P-type ATPases 0.6518264336247958 1.38885672774441 0.164876321159805 1.0 0.2398099209260479 10 P54709,P35670,Q04656,P05026,P23634,Q8NB49 6 +Receptor 0.6484027055675325 1.3529428698625954 0.1760738823775887 1.0 0.2503148619989491 31 P05556,Q14108,Q13641,Q8WTV0,P20645,Q9UQB8,A6NIH7,Q567V2,P11717 9 +Glycosyltransferase 0.6356583764873028 1.271986598358274 0.2033778809581004 1.0 0.273512589906591 21 O60512,Q16739,Q86SF2,Q93063,Q9P2E5,P15291,Q10472 7 +Writer 0.6197252898096552 1.2460009217021584 0.2127640568023983 1.0 0.2822353442465519 8 Q86X55,O96028 2 +Cysteine protease 0.6047255605372026 1.1796485272796846 0.2381400338226964 1.0 0.3047566123218129 42 P07858,Q92820,Q8NHP8,Q99538,Q13510,P53634 6 +Eraser 0.5807108432364281 1.0740116068879355 0.282817479446646 1.0 0.3419041352316596 6 Q8NB78 1 +Lipid kinase 0.5818882535588733 1.071560459694301 0.2839175011454298 1.0 0.3428467963634321 7 Q13572 1 +DMPK family 0.5719913383700238 1.061049896586886 0.2886672259154788 1.0 0.3464754693842187 3 Q13464 1 +Esterase 0.5752807635890596 0.9928561689403564 0.3207800525243378 1.0 0.3738650476072984 14 Q9UMR5,P50897 2 +Guanyl-nucleotide exchange factor 0.5546096330599601 0.9793339316965812 0.3274150099180737 1.0 0.3800382240684735 3 Q96N67 1 +Extracellular structure 0.5640307335017406 0.9783280971389428 0.3279120777252318 1.0 0.3801096652946852 8 Q92791,Q32P28,Q5KU26,Q9BXS5 4 +Metalloprotease 0.5652263479267209 0.9310570770965078 0.3518240401377617 1.0 0.3981264640248138 39 Q6P179,P52888,Q10713,Q5JRX3,Q9UIQ6,Q9BYT8,P22695,P51665,Q96KP4,P42892,O75844,P55786,Q9UHI8,Q8IYS1,Q9NZ08,P02786,O00303 17 +V-type ATPase 0.5425069943972638 0.8760617680786086 0.3809964554684955 1.0 0.418201130758894 8 P61421,Q93050 2 +SLC4 family of bicarbonate transporters 0.5113602832694024 0.7898841322132609 0.4295954390875227 1.0 0.4516810539250331 2 Q9Y6M7 1 +Signaling 0.5263382242642866 0.733049523064875 0.4635282250882677 1.0 0.4838683227274408 18 Q8IZ81,P51858,O00264,Q96GC9,Q5JRA6,Q7Z4V5,O15173 7 +Actin binding motor protein 0.5066122441959808 0.7176451510227931 0.4729761104983474 1.0 0.4932498064183935 7 P09493 1 +HDAC class I 0.4918855119504265 0.702143832649703 0.4825894692008967 1.0 0.5027854275226861 2 Q13547 1 +Enzyme modulator 0.3030766214843725 0.6696338231557654 0.5030912471412343 1.0 0.5231269354683743 129 Q86VS8,Q9UQ16,O60313,Q9H0U9,Q7L576,P05067,Q96N67,Q06481,Q9UBI6,Q9H223,O00410,Q13576,Q9UNS2,P46060,P21359,Q9Y3E7,Q8N1F8,P61586,P42566,Q9BTT0,Q9H2M9,P60953,Q9Y263,P27105,P55209,Q16181,Q01105,Q9H4M9,P52565,P11234,P46379,P11233,Q92688,P29992,Q99733 35 +Intracellular calcium-sensing protein 0.4824669779385848 0.5269394991316694 0.5982356031022711 1.0 0.6178593469570489 18 P60660,O43852,Q14257,P14649,Q9BRK5,P80303 6 +Calmodulin 0.4824669779385848 0.5269394991316694 0.5982356031022711 1.0 0.6178593469570489 18 P60660,O43852,Q14257,P14649,Q9BRK5,P80303 6 +Hsp90 family chaperone 0.4511366991437895 0.5044929690522713 0.6139150017144583 1.0 0.6337473571218203 4 P08238,Q12931,P07900 3 +Reductase 0.473472605217595 0.4926344235117242 0.6222709204230812 1.0 0.6420636340365382 17 Q9UBM7,P00374,Q7LG56,Q15392,Q14739,O95168 6 +Small GTPase 0.4745599968795496 0.4611453006989832 0.6446943625901653 1.0 0.6642399568361617 24 O95373,P60953,Q9UQ16,O60313,Q15019,P11234,P61586,P11233,P63000,Q16181,P50570,O15397,Q9UI26 13 +Transcription cofactor 0.4576874989067252 0.4444651781620486 0.6567062993135768 1.0 0.6756406472034444 14 Q93074,P56545,O14777 3 +Kinase 0.2806497122185467 0.4297055113992182 0.6674098737701977 1.0 0.6863230258126769 111 Q15375,Q8TD19,O15111,O75414,P08069,Q16539,Q8TBX8,Q9HBU6,P19784,O43293,P36896,P53350,P55263,Q13555,Q96KB5,P31751,Q9HA64,P06493,P31749,Q9UHY1,Q13572,P46020 22 +Calcium-binding protein 0.4515494583695191 0.3740374675909143 0.7083764409102307 1.0 0.726705299467563 21 P60660,O43852,Q14257,P14649,Q9BRK5,P80303 6 +SLC superfamily of solute carriers 0.4428917174602379 0.299881768604722 0.7642673412484189 1.0 0.7817947336898542 48 Q9H2J7,P41440,Q9HC07,Q6NT16,P08195,P30825,Q9UBX3,Q7L0J3,Q8IXU6,Q8TAD4,Q70HW3,Q99808,Q9Y6C9,O43772 14 +Serine protease 0.4395545173258605 0.2952912895991654 0.7677713699112605 1.0 0.7846293570310304 27 O14773,P10619,Q9HB40,Q9H3G5 4 +KRAB box transcription factor 0.3956362311407992 0.2817951077923221 0.7781006223998574 1.0 0.7948060269838239 5 O95785 1 +Membrane trafficking regulatory protein 0.4222182209608022 0.2499592581813148 0.8026188559192138 1.0 0.8178995576025877 22 P11279,O43731,P13473 3 +Translation initiation factor 0.4202149088234829 0.2480136175864322 0.804123870601491 1.0 0.8190433905603198 21 O60573,P55010,Q15056,O75153,O75822,P23588,P55884,P63241 8 +Histone deacetylase 0.3783943329397889 0.2440364359918089 0.8072026009812996 1.0 0.8217882875420649 3 Q13547,Q92769 2 +Unclassified protein 0.4170482844300938 0.236134298486992 0.8133284600139759 1.0 0.8268453147625462 21 Q9HA64,Q9HBU6 2 +CMGC group 0.4055557856721047 0.2336465383442791 0.8152593951537399 1.0 0.8284149810271273 15 Q16539,P19784 2 +Heterotrimeric G-protein 0.3829141744104406 0.2043917581242276 0.838047370308088 1.0 0.851166707699059 9 Q9UBI6 1 +Other group 0.3782042589751567 0.1587239359848284 0.8738863790533169 1.0 0.886725468034669 13 P53350,Q8TD19,O15111,Q9UHY1 4 +C2H2 zinc finger transcription factor 0.3574248800197158 0.1456183904637526 0.8842226492499248 1.0 0.8959397501391807 7 O95785,Q9UQR1 2 +Non-motor microtubule binding protein 0.3721014511987256 0.1128848031762977 0.9101218846216268 1.0 0.9204397519957028 17 Q15555,Q9UN37,Q9UH99 3 +Ca2+-ATPases 0.3212316561847829 0.083110149344287 0.933763955758657 1.0 0.9425688964070178 4 P23634 1 +Enzyme 0.2750737131846836 0.0754473983109087 0.9398587482472692 1.0 0.9482740716293134 675 Q6YP21,P07858,P34059,Q9UIQ6,Q15392,P16278,Q9NRB3,P42892,Q9BW91,O14773,Q6ZRP7,Q9H3G5,Q9UMR5,Q9UNK9,Q08431,P38571,Q9NZ08,P07384,P02786,Q9NP77,Q9UJ14,Q5JPH6,Q8NHP8,O60512,Q99538,Q86SF2,P06865,Q9Y697,P11117,Q9HB40,P61457,Q13423,Q10472,P19021,P50897,P15586,P55786,P53634,Q9HAT2,P10253,Q8NCH0,Q9UBM7,Q8TCT8,O43674,Q92820,P10619,Q8N4Q0,Q8NBZ7,Q13510,Q9P2E5,P07686,Q9NX62,O95251,P15291,O15260,Q9UHI8,P42785,Q8NCC3,O00462,Q6P179,Q99519,P00374,Q16739,P14406,Q9BYT8,Q93063,Q96N66,Q5BJF2,Q10471,P17655 70 +Methyltransferase 0.3415092911328921 0.061337033821045 0.9510907975886184 1.0 0.959154685651075 13 A6NJ78,Q9UBP6,O43709 3 +Ubiquitin-protein ligase 0.3486842023276578 0.0516600619256659 0.958799560688394 1.0 0.9664735684716814 17 Q13619,O94822,P46934,Q13620,Q9Y4X5 5 +CAMK group 0.3003455195441032 0.0166118095703995 0.986746303184088 1.0 0.9941759224080624 8 O43293 1 +Translation factor 0.3571644785353324 0.0151760577545401 0.9878917226073188 1.0 0.9948617959088756 27 Q14671,O60573,P55010,Q15056,O75153,O75822,P23588,P55884,P63241 9 +G-protein 0.3683481340431466 0.0098740382264241 0.992121785363131 1.0 0.998651971068389 35 O95373,P60953,O15397,Q9UQ16,P08754,O60313,Q9NTK5,P11234,P61586,P11233,Q9UBI6,P63000,Q16181,P29992,P50570,Q15019,Q9UI26 17 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3a558ea6c015e2548998cb5901991637736f0b64 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome non-ATPase regulatory subunit 9", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A disintegrin and metalloproteinase with thrombospondin motifs 1", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit delta, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Activin receptor type-1b", "Acyl carrier protein, mitochondrial", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase b", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-1,4-galactosyltransferase 3", "Beta-centractin", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional coenzyme A synthase", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, cytosolic", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 12", "Carbohydrate sulfotransferase 14", "Carbonyl reductase family member 4", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-3", "Caspase-7", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 135 kDa", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride transport protein 6", "Chondroitin sulfate glucuronyltransferase", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-6/CLCN6 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coiled-coil domain-containing protein 28A", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 1", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 2-associated protein 1", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoplasmic dynein 2 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DAPK family", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-associated protein kinase 3", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Dr1-associated corepressor", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "ETS-related transcription factor Elf-2", "Early endosome antigen 1", "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Ephrin-B1", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione hydrolase 7", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(q) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Homeobox protein cut-like 1", "Homeodomain transcription factor", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "INSR family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KHS subfamily", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin heavy chain isoform 5C", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18A", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIF7", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAP7 domain-containing protein 1", "MAP7 domain-containing protein 3", "MAPK family", "MCU family", "MFS-type transporter SLC18B1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 20", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Membrane-bound signaling molecule", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylsterol monooxygenase 1", "Methyltransferase", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase kinase 5", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosamine-6-sulfatase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Nocturnin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 6", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Opioid growth factor receptor", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDHK subfamily", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ domain-containing protein 11", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 23", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-glycine alpha-amidating monooxygenase", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Pirin", "Plant homeodomain", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable leucine--tRNA ligase, mitochondrial", "Probable methyltransferase-like protein 15", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein FAM177A1", "Protein Hook homolog 3", "Protein LSM14 homolog A", "Protein LSM14 homolog B", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RAF family", "RIO family", "RIO2 subfamily", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II elongation factor ELL", "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "Ral GTPase-activating protein subunit alpha-1", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Ral-B", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor expression-enhancing protein 6", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoic acid-induced protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLIT-ROBO Rho GTPase-activating protein 2", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STE group", "STE20 family", "STE7 family", "STKR Type 1 subfamily", "STKR family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Sentrin-specific protease 1", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 11-interacting protein", "Serine/threonine-protein kinase a-raf", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialate O-acetylesterase", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-dependent HCO3- transporters", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transcriptional repressor protein YY1", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 1", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter 7", "Zinc transporter SLC39A7", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA dimethylallyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANGEL1", "ANKS1A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARAF", "ARCN1", "ARFIP1", "ARHGDIA", "ARID3B", "ARIH1", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDK", "BCLAF1", "BET1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBR4", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC28A", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CEP135", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUX1", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DAPK3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELF2", "ELL", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENPP1", "EPHA7", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERH", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTB", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GGT7", "GID8", "GINS2", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK3", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT3", "LRRC47", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4K5", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBNL1", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED12", "MED14", "MED20", "METAP1", "METTL1", "METTL15", "MFGE8", "MFN1", "MFN2", "MFSD3", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "ND1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS7", "NDUFS8", "NEDD4", "NEK9", "NEU1", "NF1", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOC4L", "NOCT", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OGFR", "OLA1", "OPA1", "ORC3", "OTUB1", "OXA1L", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAFAH2", "PAICS", "PAIP1", "PAK2", "PAK4", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDZD11", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF10", "PHF14", "PHF23", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RAI1", "RALA", "RALB", "RALGAPA1", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RNASEH2A", "RNGTT", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SALL2", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIAE", "SIN3A", "SIN3B", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRGAP2", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAT1", "STAT3", "STK11IP", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TJP1", "TJP2", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIT1", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS72", "VRK1", "WARS", "WASF2", "WASHC5", "WDR1", "WDR33", "WDR34", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF148", "ZNF281", "ZNF598", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ACP2", "ACVR1B", "ADAMTS1", "ADK", "AKT1", "AKT2", "ANGEL1", "ANP32B", "ANP32E", "AP1M1", "AP3S1", "APLP2", "APP", "ARHGDIA", "ARIH1", "ASAH1", "ATP11C", "ATP1B1", "ATP1B3", "ATP2B4", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BUD23", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CDC42", "CDK1", "CHMP3", "CHPF2", "CHST12", "CHST14", "CHUK", "CLCN3", "CLCN6", "CLUH", "CNDP2", "COLEC12", "COPS3", "COX7A2", "CPVL", "CSNK2A2", "CTBP2", "CTSA", "CTSB", "CTSC", "CUL4A", "CUL4B", "CYFIP1", "DAPK3", "DHCR24", "DHCR7", "DHFR", "DNM2", "DNM3", "DOCK7", "DSC3", "EARS2", "ECE1", "EHD1", "EHD4", "EIF3B", "EIF3F", "EIF3J", "EIF4B", "EIF4E2", "EIF4H", "EIF5", "EIF5A", "ELMOD2", "EPHA7", "EPS15", "ERAP1", "ERAP2", "ETNK1", "EXOC3", "EXOC6", "EXT2", "FN3KRP", "GAA", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GGH", "GGT7", "GID8", "GLB1", "GM2A", "GNA11", "GNAI3", "GNG12", "GNS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HEXA", "HEXB", "HOOK3", "HSP90AA1", "HSP90AB1", "IGF1R", "IGF2R", "IMPAD1", "IPO11", "IPO5", "IPO7", "IPO8", "IQGAP2", "ITGB1", "ITPK1", "KAT7", "KDELR3", "KDM1B", "KYAT3", "LAMP1", "LAMP2", "LBR", "LGMN", "LIPA", "LMAN2", "LNPEP", "LTN1", "M6PR", "MANBA", "MAPK14", "MAPRE2", "MBOAT7", "MCAM", "MED12", "METTL1", "METTL15", "MFGE8", "MIA3", "MPV17L2", "MTCH2", "MYL6", "MYL6B", "NAP1L1", "NAP1L4", "NDC80", "NDUFB4", "NDUFB5", "NEDD4", "NEK9", "NEU1", "NF1", "NFS1", "NLN", "NME6", "NNT", "NPEPPS", "NRBP1", "NSD2", "NUCB2", "NUDT9", "OLA1", "OPA1", "OXA1L", "P3H1", "P3H4", "PAM", "PBK", "PCBD1", "PGRMC1", "PGRMC2", "PHKA1", "PIP4K2C", "PITRM1", "PLA2G15", "PLAA", "PLBD2", "PLK1", "PM20D2", "PMPCA", "PPT1", "PPT2", "PRCP", "PSMD7", "PUM1", "QSOX2", "RAB3GAP2", "RAC1", "RALA", "RALB", "RANGAP1", "RCN2", "REEP3", "RHOA", "ROCK1", "RRM2B", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SDF4", "SEPT2", "SEPT7", "SET", "SIAE", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A20", "SLC25A26", "SLC29A1", "SLC30A5", "SLC35F2", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SNAP47", "SORT1", "SPPL2A", "SSU72", "STK11IP", "STOM", "STX12", "STX3", "STX5", "STX6", "STX7", "SUN2", "SURF4", "SV2A", "TFRC", "TGOLN2", "THOP1", "TM9SF2", "TM9SF3", "TM9SF4", "TMEM165", "TMEM97", "TPBG", "TPM1", "TPP1", "TRAP1", "TSPYL1", "TTYH3", "TUBB2A", "TUBB6", "TUBG1", "UGCG", "UNC119B", "UQCRC2", "UXS1", "VMP1", "VPS4A", "WIZ", "ZADH2", "ZMPSTE24", "ZNF148"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..577277ffe210c7e974817cc6f2273abdcf58fb6c --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..08806e74df153100fd70c1d5ad6c27d5b260b56a --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ffc85da43ecbe8191315ec4726240ee10c6a6f097af2b9ca2fb02f9ce9e5d8c0 +size 213151 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d028f5625d27237f59fab46341f00a1eeed81f3f --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tchem", "1": "Tdark", "2": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..89b15467602ac41c262d34991f47a9d4dc061cc0 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a700b081923fcb9aeac0636043b1510876b07aed2142def65deb27fd4f0e92b +size 126860 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6eb0cf7fe8423daf1a519fd2839136f3d07f1248 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6523e118dfe6df4673520297c6ad9453e7825fc29c30951c7c24b12c2308352f +size 134142 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9769ed74dedae43e2ed14622a869834f1b4e7e91 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81441d2e8d3f0fe547518fda8552340dfb616e5f1c6288d803a5d4aeafcc0bf5 +size 137561 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e7aa6031004cd5287055e79aab5168f78710210e --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0d6359dc74915980f65e7d1ba28bb2c375758c760978737bfeb0f6d8bd5dfe4 +size 76357 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..72504c490edc1c4571d12db963232a66b0695f98 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tchem 71 329 2.091886030334027 0.0364487120316541 59.439320388349515 318.5218446601942 -0.2305334187536127 0.615521577515179 22.555943558835885 30.16438793527643 1.14481176642065 0.379503350430493 6.520464467638695e-07 0.0033924765372901 2.597187376201826e-06 9.79229048252934e-06 1.357844777178312e-06 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e023e9b8fddb6b0fea5bfe6d5f39fbc48b363ac4 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 847.5 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..501c1b8a14b8039b1609233a489db86d639ec34f --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c41dadf4278b9c076ff64f4aa7072f75c416bba6 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tchem 0.3645908190216387 2.091886030334027 0.0364487120316541 0.1380157212497442 0.1457948481266164 329 Q15375,P07858,Q99523,O15111,Q9UIQ6,P04062,P05067,P16278,Q9H9B1,P42892,P08183,Q02818,Q13564,P38571,P11717,Q9NZ08,P07384,P10586,Q9H2J7,P13674,P04066,Q16539,Q99538,P06865,P08236,Q8TBX8,Q8WTV0,Q9BTY2,P19784,P68402,P51797,O43293,P19021,P55786,P53634,Q15904,P36896,P19623,P11413,Q9UBM7,P53350,Q92820,P10619,P51790,P04114,P31751,Q13555,Q13510,P56545,P07686,P06493,Q9UHI8,P42785,Q86X55,O43598,Q15125,P48449,O00462,Q6P179,P06756,P46934,O00754,P31749,P51798,Q15056,P31946,Q5BJF2,P40763,P17655,Q13126,Q4J6C6 71 +Tdark 0.271505857832589 0.3971851382568608 0.691230940723017 0.9909106024577896 0.995158374695427 370 Q9H813,Q5T6V5,Q6P4E1,Q8IYS2,Q9H1Z9,Q8NC54,Q9NVU7,Q5SWX8,Q9NX00,O15126,Q9NVZ3,Q96IX5,Q5SQN1,P14649,Q69YU5,Q9ULR0,O75071,Q9NSK0,Q99805,Q9NWU5,O60830,Q9NRY5,Q8N1F8,Q9BU23,Q8NBN3,Q86SX3,Q8ND04,Q9HD45,Q9H1I8,Q9NPR9,O43731,Q8IXU6,Q9NX62,A0MZ66,Q8WUX2,Q5VW38,Q9BTE7,Q9NUD5,Q9NWR8,P14406,Q9GZU8,Q6AI08,Q9GZP4,Q9P0I2,Q96EY4,Q9BWH2,Q3SXM5,Q9P013,Q9Y2W6,Q05D32 50 +Tclin 0.338098397920729 0.3234310982954816 0.7463687810215702 0.995861806102908 0.995158374695427 91 P05556,P54709,P08069,P26358,Q9BUF5,O95168,P31350,P06280,Q9Y6M9,Q13464,P00390,Q99808,P10253,Q8N183,O43674,P49721,Q7L0J3,P62942,P20618,Q99720,P00374,Q16739,O75489,O96000,P28074 25 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a63dcc285f2f2a75ad6ef7d1590fb2e05c92c2e2 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCS1L", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOLA3", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C11orf54", "C12orf29", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC138", "CCDC167", "CCDC22", "CCDC28A", "CCDC47", "CCDC6", "CCDC85C", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPO", "CENPP", "CENPV", "CEP135", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG3", "COG4", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUX1", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM2", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOCS2", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2AS2", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PAXX", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "Q6ZSR9", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RMND1", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", 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100644 index 0000000000000000000000000000000000000000..109d6db63f424b87f1f247630b169ca6f3b7988d --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Notch signaling pathway 1 6 2.227874577549985 0.0258888798982739 1.9757281553398056 6.567961165048544 0.3580302610928835 0.4728395764519008 1.347198893311346 1.4523976555847773 0.9900461875966045 0.3093333899584488 0.2206433814734211 0.1457663642848915 0.266209970857853 0.182300940685854 0.4647244871500471 +Amino-acid transport 3 7 2.121531166422018 0.0338771280420215 3.063106796116505 7.016990291262136 0.9299828460487652 0.271909550896337 1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 0.2021881519424126 0.1330370821365251 0.2445730022705269 0.0326106125072858 0.0498364179528963 diff --git 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b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..71a8cbf432a8c047b50bfe240b8a8c2442faec1a --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,45 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Copper transport 0.9215107701386782 2.6503740404427516 0.0080402701790021 0.7505547939852022 0.1053522168791206 2 P35670 1 +Neurotransmitter transport 0.8882413147690291 2.501203042390887 0.0123772194433544 0.8825997560344009 0.1158494454813036 4 Q9H2J7,Q7L0J3 2 +Notch signaling pathway 0.82767787582651 2.227874577549985 0.0258888798982739 0.9890184866665528 0.1781154937001246 6 P05067 1 +Molybdenum cofactor biosynthesis 0.8201878941426095 2.2094091533580524 0.0271461949407523 0.9912060482022892 0.1795825203772846 3 Q9Y697 1 +Chemotaxis 0.8133674954763379 2.173711035836856 0.0297268433435506 0.994431081896801 0.189371002040397 4 O94813 1 +Amino-acid transport 0.8048131379411897 2.121531166422018 0.0338771280420215 0.9973358016381008 0.1924803414928048 7 Q9H2J7,Q6P4A7,P08195 3 +Peroxisome biogenesis 0.7358586877334827 1.8224927079509157 0.0683802591797868 0.999994882552436 0.2902827979331195 4 P40855,P56589 2 +Adaptive immunity 0.7410666295336253 1.807450074659691 0.0706921323455374 0.9999966622515568 0.2902827979331195 13 P04083,P10321,Q6P179,P01889,Q9NZ08,Q07021,P04439 7 +Sphingolipid metabolism 0.7396817703848192 1.8062262335529324 0.0708830087976222 0.9999967781212292 0.2902827979331195 11 P17900,P04062,Q13510,P07602 4 +Cell adhesion 0.7166818677564547 1.7665427211111748 0.0773048409058787 0.9999990227230832 0.3002492864295705 37 Q08722,P23229,P05556,Q14574,Q9BY67,P06756,P19022,P05067,P43121,Q96GC9,P78310,Q08380,Q14126,Q08431,Q92859 15 +Glycogen biosynthesis 0.7163060833537411 1.7184542853480786 0.0857137859704515 0.9999997976358987 0.3013315886469585 6 P31751,P31749 2 +Sodium/potassium transport 0.7046095612082809 1.6852564126603606 0.0919391113053431 0.9999999375151224 0.3013315886469585 3 P54709 1 +Sugar transport 0.7037148588728571 1.6811032866564215 0.0927428541276504 0.999999946342754 0.3013315886469585 3 P31749 1 +Cell shape 0.6920700531310924 1.604579278198617 0.108586424715906 0.9999999974080304 0.3220149146747559 6 Q96AC1,Q7L576,P35580,P15311 4 +Purine salvage 0.6857959105068071 1.5821526347464856 0.1136147302247505 0.9999999990203404 0.3256955599776182 5 Q13126 1 +Endocytosis 0.6578299184713338 1.4995756788951675 0.1337243516195687 0.9999999999810832 0.359384194977591 43 Q99523,Q9UQ16,Q9NVZ3,P05067,P98164,Q9UBG0,P02786,Q07954 8 +Antiport 0.6547253622414225 1.4084550695380635 0.1589963623935157 0.9999999999998838 0.4081697661445479 9 P51798,P51797,P51790 3 +GPI-anchor biosynthesis 0.6378820000369549 1.3552952564157466 0.1753235057374456 0.999999999999996 0.4240842675261245 5 Q9H490 1 +Host-virus interaction 0.3210664558783011 1.2255865959983918 0.2203542844859316 1.0 0.4922199601503927 245 P10321,P05556,O15118,P08069,Q9Y624,P02786,Q8IZA0,P28070,Q14108,Q8WTV0,Q9Y4E8,P01889,P78310,Q07021,Q9BY67,Q9UPY3,P62258,P11279,P49721,P56545,P49720,Q86X55,Q00403,P04439,Q7Z739,Q01105,P06756,P46934,Q9UBW8,Q15056,P31946,O60934,P40763,P28074,P28072 35 +Glycogen metabolism 0.5702709516834165 1.008160474858101 0.3133774292978195 1.0 0.6267548585956391 8 P31751,P31749 2 +Angiogenesis 0.5601445849385569 0.9377110016965868 0.3483929484300212 1.0 0.6450585366871308 11 Q08431,Q13685 2 +Inflammatory response 0.5269364975202049 0.7868433665832057 0.4313735635509312 1.0 0.7215928347015644 10 Q8IV08 1 +Immunity 0.4523475416440483 0.7209120595569473 0.4709636226100615 1.0 0.7500531767493572 74 P04083,P10321,Q9BY67,Q8IV08,Q9NUD5,Q6P179,P46379,P01889,O00584,Q9NZ08,Q07021,P04439 12 +Apoptosis 0.2985453840652379 0.6147732804547665 0.5387044573065283 1.0 0.8272961308635969 125 Q15375,O75414,Q14728,P05067,Q9H2J4,Q13564,Q16539,Q9Y3E7,O43464,P19784,O43293,Q07021,Q9BY67,P31751,Q9BX68,Q9H3K2,P06493,O60333,Q9UNN5,Q9NXR7,Q9H8M7,Q15041,P31749,P46379,O95831 25 +DNA condensation 0.4579025110782894 0.5122594140141911 0.6084694660251606 1.0 0.8978920898256938 6 Q15021,Q15003,O95347,Q9NTJ3,P42695 5 +Lipid degradation 0.4745989747874166 0.4857541141809042 0.6271415112158154 1.0 0.8978920898256938 19 Q8NCC3,P38571,Q99519,Q8NHP8 4 +Differentiation 0.3929705498642243 0.4829489899403347 0.6291319557821364 1.0 0.8978920898256938 82 Q9BY67,Q99523,Q13555,Q99829,Q96N67,P56545,P46379,Q14444,Q16527,Q9Y2W6,Q16352,Q13685,Q14671,Q96EK5,Q16181,O94813 16 +Cholesterol metabolism 0.4747972326885818 0.4622300159314197 0.6439163803978962 1.0 0.8978920898256938 24 Q9UBM7,O15118,P04062,Q15392,P61916 5 +Exocytosis 0.4589363748815239 0.435804661206861 0.6629784616736227 1.0 0.8978920898256938 16 O60645,Q15334,Q8TAG9,P11233,Q5JRA6,Q9BRK5 6 +Cilium biogenesis/degradation 0.4664694232155846 0.4165526214065322 0.6770056702128155 1.0 0.9026742269504208 26 Q9Y496,P61421,Q8NCM8,Q9H4M9,O15078,Q9H3S7,Q9P2S5,A6NIH7,Q7Z3E5,Q96C92,Q15154 11 +Carbohydrate metabolism 0.4505262977295516 0.3321807955802869 0.739752744125008 1.0 0.9478930436353754 30 Q9NRB3,Q99519,Q8NCH0,P31749 4 +Innate immunity 0.4338474590449446 0.3049148618948872 0.7604309962839069 1.0 0.954701688765197 57 P04083,P10321,P01889,O00584,Q07021,P04439 6 +Ion transport 0.4141878949492308 0.2604796568841817 0.7944938053143693 1.0 0.959473406016444 64 Q9H813,Q9H2J7,P61421,P51790,Q9NWR8,Q9C0H2,Q9Y487,P35670,Q04656,P51797,Q8TAD4,Q15904,Q93050 13 +Transcription termination 0.3831168831168809 0.2593461054392196 0.7953682089540937 1.0 0.959473406016444 3 Q9H0D6,Q9UNY4 2 +Sterol metabolism 0.4152838496705533 0.203266436292245 0.8389267878401594 1.0 0.9816014116224996 26 Q9UBM7,O15118,P04062,Q15392,P61916 5 +Spermatogenesis 0.406701106396437 0.181843332528592 0.855705676967419 1.0 0.9865399672798226 24 Q14671,Q9BY67,Q16181,P46379 4 +Transport 0.2670216784645745 0.1627089527539505 0.8707475976536574 1.0 0.9865399672798226 550 Q9H813,Q99523,Q9C0H2,P54709,P98164,P57737,P23634,O00410,P11717,Q8TEX9,Q9H2J7,Q9H3S7,Q9Y6M1,Q15904,Q99808,Q96MW5,Q8NE01,Q8NC96,P51790,Q9BQE5,Q7L0J3,O94886,Q8IXU6,P61916,A6NIH7,Q8WUX9,Q8NFH5,Q99720,P63241,O43772,Q9NQ11,Q8NEW0,P35670,O75489,P43034,P31749,P22570,Q9UBF2,Q99747,Q9BRG1,Q9UL25,P50416,O60831,Q8N4H5,Q86VS8,Q8TD16,P08195,Q15629,O15118,Q13190,Q9H173,O43752,O60830,Q9Y6B6,O00461,Q96D46,Q93050,O43674,P04114,P31751,Q9NV96,O43731,Q96BM9,Q6P4A7,Q9NUM4,Q9UN37,Q6UWE0,Q92572,Q9NVU7,O60645,Q13277,Q9UBX3,Q9NVZ3,Q04656,P51797,P20645,P84085,Q99595,O60784,P61421,Q9Y282,Q9Y487,Q86Y82,Q8TAD4,Q5JRA6,Q9NWR8,Q9H4M9,P46379,P51798,O14949,Q9Y6C9,O15126,P30825,Q14728,Q8TAG9,Q9C0C9,Q9UJU6,P08183,Q969X5,O95168,O15027,Q12907,Q6NT16,Q9Y3E7,P22695,Q92783,Q8NB49,Q70HW3,P00403,Q9ULC3,Q14203,P41440,O96000,O14828,O95486,Q99643 116 +Lipid transport 0.4027447468372949 0.1577532808370641 0.8746512140607923 1.0 0.9865399672798226 26 P61916,O15118,P04114,Q99720 4 +Pyrimidine biosynthesis 0.3490844654459604 0.1401461819399442 0.8885444927107526 1.0 0.9865399672798226 5 P17812,P30085,P11172,Q9NRF8 4 +Glucose metabolism 0.37115598265352 0.1378900591126574 0.8903273070360227 1.0 0.9865399672798226 13 P31751,P31749 2 +Steroid metabolism 0.3952871600177409 0.1226733586096516 0.9023657612427184 1.0 0.9865399672798226 28 Q9UBM7,O15118,P04062,Q15392,P61916 5 +Cholesterol biosynthesis 0.3533517237990337 0.0827957751385405 0.9340139285458456 1.0 0.9963445588611406 14 Q9UBM7,Q15392 2 +Neurogenesis 0.3935458084983353 0.0772589459623022 0.9384175496250278 1.0 0.9963445588611406 52 Q15375,Q8WUB8,Q13555,P60953,Q9Y263,P46934,Q7L576,Q96N67,P43034,P31749,P98164,P55209,Q16352,Q8WUJ1,Q96EK5,O94813,Q9ULH0 17 +Nucleotide metabolism 0.3222478942559859 0.0412988307748118 0.9670576651832477 1.0 1.0 10 O43598 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..14dcf11ecd4e46e74c46fe6985fb2f0e48bc0346 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOB", "APOBEC3C", "APOL2", "APOO", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARHGAP35", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARL8B", "ARMC9", "ARMT1", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATRX", "AUP1", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCL2L12", "BCLAF1", "BCOR", "BET1", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD2L", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP3", "CASP7", "CBR4", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLINT1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG6", "COG7", "COG8", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COQ9", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREG1", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DRAP1", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENPP1", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1L", "FOXK1", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GID8", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HGS", "HIBADH", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK3", "HOXD11", "HOXD13", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRF2BP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1B", "KIF20A", "KIF20B", "KIF2A", "KIF2C", "KIF3A", "KIF5C", "KIFBP", "KIFC1", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LPCAT1", "LPCAT3", "LPGAT1", "LRP1", "LRP2", "LRPPRC", "LRRC41", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAP1S", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MESD", "METTL1", "METTL3", "MFGE8", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MIA3", "MICALL1", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP5", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NES", "NEU1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NOC2L", "NOCT", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRDE2", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGFR", "OGT", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD6B", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATZ1", "PAXX", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK2", "PDK3", "PDS5A", "PDS5B", "PDSS1", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF2", "PHF23", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMAIP1", "PMF1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POP4", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", 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a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a924014463b23ccb484e154326e644664a125dc0 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Neuronal ceroid lipofuscinosis 4 5 2.8486681910130143 0.004390264115728 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 1.576396912287629e-06 0.0015075035399645 3.74476751148508e-06 5.632723326964323e-06 0.0001575214550341 +Gangliosidosis 4 5 2.7983906015835416 0.0051357963731073 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 1.659464902331861e-08 1.102140235687858e-06 3.9836639152197847e-08 8.183074903921214e-09 2.6454681464607386e-07 +Neurodegeneration 21 139 2.741414342097338 0.0061175309206435 27.95631067961165 134.69660194174756 0.269943056894121 0.615157984625689 9.104465669482156 13.994023970959963 0.954862652984542 0.3632698211987682 2.766762652773219e-06 0.0031932907778462 5.057635507969956e-06 0.0003506301026642 0.0002728115792795 +Mucopolysaccharidosis 4 6 2.7039230525633493 0.0068526155699066 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0031158708456652 0.0526645480715484 0.0001343549216781 3.3521637524966083e-06 9.569573614901708e-05 +Amyloidosis 1 5 2.4599207842938102 0.0138967685183251 1.087378640776699 3.703883495145631 0.4647215876526214 0.3864606223560753 0.9068969404042873 1.1014925734380785 1.1974619704686245 0.3115672738393393 0.0058302631141811 0.0023758658868836 0.0088504827764808 0.050241067872642 0.1630814235328921 +Alzheimer disease 0 5 1.9980272141397404 0.0457137097948301 1.2354368932038835 4.759708737864078 0.431847000352495 0.4019540870993141 1.112770771411099 1.1095472323418396 1.1278893369824603 0.2998522373047794 0.1171014210767626 0.0756950383436983 0.1432798584585485 0.3258327648280404 0.5492603500015365 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1843e4d4338568ae2d71cd20e49a8ec6d8e76fd4 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 118, + "title": "Average number of proteins per term", + "value": 22.83050847457627 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c1d469e8b434bdc1c14415211551b47726963445 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..510a333048c9978d437888629a9e8da6ce38086d --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,47 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Neuronal ceroid lipofuscinosis 0.9713526284701696 2.8486681910130143 0.004390264115728 0.4049987042772871 0.0628647991298084 5 O14773,Q9NWW5,P50897,O75503 4 +Niemann-Pick disease 0.959575095898493 2.8083214686417306 0.0049800486759439 0.4451812927642069 0.0628647991298084 2 P61916 1 +Gaucher disease 0.9592800236057788 2.807108456028049 0.0049988408352026 0.4464163817723292 0.0628647991298084 2 P07602 1 +Gangliosidosis 0.9592439456585912 2.7983906015835416 0.0051357963731073 0.455335640813063 0.0628647991298084 5 P07686,P06865,P17900,P07602 4 +Neurodegeneration 0.4480254492958528 2.741414342097338 0.0061175309206435 0.5152324213379997 0.0628647991298084 139 Q8TD16,P04062,P05067,Q04656,O75503,O14773,Q9Y287,P07384,P06865,Q14108,P54802,P50897,Q8IV08,Q13510,P07686,Q9NWW5,Q99720,Q9NQ11,Q15041,Q9NUM4,Q6UWE0 21 +Mucopolysaccharidosis 0.9372558605294432 2.7039230525633493 0.0068526155699066 0.5557607017435271 0.0628647991298084 6 P15586,P54802,P16278,P34059 4 +Hirschsprung disease 0.9167896134552868 2.630575611915195 0.008524040559974 0.6358349939693987 0.0628647991298084 2 P42892 1 +Amyloidosis 0.8795597466309497 2.4599207842938102 0.0138967685183251 0.8082033242966078 0.0863062465874928 5 P05067 1 +Dystroglycanopathy 0.797780273670913 2.1040513164386625 0.0353739708843405 0.9857321269236708 0.1739220235146745 4 O43505 1 +Hypotrichosis 0.7539083671850284 1.8931549235888403 0.0583372699105315 0.9991688965918968 0.237372339635956 6 Q14574,P48449 2 +Glycogen storage disease 0.7054989626811852 1.6431512436124107 0.1003516447249284 0.999996192944063 0.3588331538648955 11 P10253,P46020,P13473 3 +Hereditary nonpolyposis colorectal cancer 0.6676505312868939 1.512715023702742 0.13035206171112 0.9999999304127524 0.4046949883799735 3 P43246,P52701 2 +Spinocerebellar ataxia 0.6748286075012374 1.5051648886250115 0.1322816897121468 0.9999999464580848 0.4046949883799735 9 O14773,Q8IV08 2 +Joubert syndrome 0.6580412640261031 1.459141042340065 0.1445262919677701 0.999999989991093 0.4060500583856398 4 Q7Z3E5 1 +Congenital muscular dystrophy 0.6332742268811217 1.3333715389158782 0.1824099075700409 0.9999999999522248 0.4579652998566985 5 O43505 1 +Cancer-related genes 0.3097992361271933 1.2559921562821543 0.2091188139345114 0.9999999999990512 0.4935204008854471 393 P07858,Q9UNF1,Q9NVC6,Q96ST3,Q08431,P11717,Q92859,P02786,P15311,O95071,Q99538,Q9HBU6,Q13620,P61586,P33993,P00390,Q08380,Q8WYA6,Q9UHI8,Q86X55,Q8WVQ1,P35670,Q93063,P31749,P80303,Q15375,P08195,P21359,Q93074,P08236,P01889,P36896,Q07021,P04083,P31751,P67809,P04439,P00374,Q9UDY2,Q01105,P09493,P10644,Q15056,P40763,Q99543,Q9BZK7,Q16204,P08069,Q16539,Q9NQX3,P68402,Q13472,Q99595,O60784,P23229,P62258,Q9H2U2,O96028,P06756,P31946,O60934,P05556,Q8IWS0,P08183,P67936,P19784,P11413,P53350,Q9UPY3,P06493,Q14203,P41440,Q13867,Q9UNN5,Q04917,P29992,P29375,Q99643 78 +Williams-Beuren syndrome 0.6154240542770383 1.225273640060223 0.2204721367181426 0.9999999999998278 0.5038843268097578 8 Q9Y4P3,O43709,Q15056 3 +Disease variant 0.3102152191173826 1.192717107058139 0.2329801835356209 0.9999999999999744 0.5091048455037641 857 Q8TD19,Q69YQ0,Q10713,P07602,P34059,Q04446,P56589,O60313,P17900,P05067,Q9UNF1,Q15392,O75503,P98164,P42892,Q9UBS4,O14773,Q9NVC6,O00584,Q9Y287,Q96ST3,Q14739,P02786,Q07954,Q9BUF5,P49591,P17480,P04066,P06280,Q9Y4J8,P06865,Q14108,Q9H3S7,Q13620,P61586,P54802,P12814,P00390,P50897,P15586,Q9Y4X5,P53634,Q15904,Q9HAT2,P10253,Q8NCH0,Q8IV08,P10619,P13473,Q13510,P07686,Q9NX62,P61916,O43567,Q9NWW5,O43505,Q99720,P48449,Q99519,Q8WVQ1,Q9NQ11,Q9BV79,P35670,Q93063,O00754,P31749,Q92542,Q8TD16,O15118,P04062,Q8N6M0,P16278,Q13190,Q9H173,P38571,P21359,Q9Y6B6,P28070,Q93074,P08236,P61457,Q14126,Q07021,Q9UBM7,P04114,P31751,Q96PZ0,P00374,Q9UDY2,Q01105,P09493,P10644,Q15041,Q96N66,Q9NUM4,Q10471,P40763,Q9UN37,Q6UWE0,Q9BZK7,Q9UBX3,Q04656,O15460,P08069,P07384,Q5JPH6,O43395,O43909,Q9NQX3,Q13423,Q13472,Q14671,Q8TAA9,Q9Y4U1,P23258,Q9H2U2,Q7LBC6,Q15125,Q9BQP7,P19022,Q6IA86,P51798,O14949,O60934,P35270,O95831,Q4J6C6,Q7KZN9,Q9H9B1,Q8IWS0,P51648,O75787,Q969X5,Q9H490,Q9C0B1,O43464,P22695,Q8NB49,Q70HW3,P11413,Q8N183,O43292,Q13144,Q9UPY3,P00403,O60333,Q9ULC3,Q96RR1,P54098,Q9GZZ9,P46020,P29992,O75844,Q9H9S5 154 +Progressive external ophthalmoplegia 0.5673266980210319 1.0020219805910868 0.316332976919506 1.0 0.5924966869285986 7 Q96RR1,P54098,Q9BQP7,Q13472 4 +FDA approved drug targets 0.3124077858440838 0.8139849715693298 0.4156535604157738 1.0 0.7006731447008759 125 P00374,P04083,Q16739,P06756,P49721,Q7L0J3,P05067,P62942,Q13423,P23258,P20645,P08069,P28074,P10253,Q99720,P02786 16 +Ichthyosis 0.505259952657245 0.6942540502491082 0.4875229016969804 1.0 0.7811355806526111 9 P04062,Q15125 2 +Dyskeratosis congenita 0.4968420340999794 0.6924594248185177 0.4886488584499677 1.0 0.7811355806526111 5 Q9NX24 1 +Epidermolysis bullosa 0.492428686868092 0.6830197544736896 0.4945943599162632 1.0 0.7811355806526111 4 P23229 1 +Premature ovarian failure 0.489374262101531 0.6800315577081796 0.4964844792283545 1.0 0.7811355806526111 3 Q06787,O60879 2 +Lissencephaly 0.4978709411755954 0.644439712311698 0.5192903397776341 1.0 0.7957955856332574 11 P23258,O43505,Q9H9S5 3 +Parkinsonism 0.4870769655183581 0.587917096128609 0.556587940637755 1.0 0.8420176537853216 12 O75787,P04062,O43464,Q9NQ11 4 +Senior-Loken syndrome 0.4470345234582524 0.5090679686463929 0.6107045829417062 1.0 0.899548544580044 2 O15078 1 +Nephronophthisis 0.4471664698937374 0.4987040119325674 0.6179879178469929 1.0 0.899548544580044 3 Q9NQH7,O15078 2 +Leber congenital amaurosis 0.4472984942427064 0.4886210525992337 0.6251100055556238 1.0 0.899548544580044 4 P20839,O15078,P68371 3 +Hypogonadotropic hypogonadism 0.4272646798465777 0.4295228615694862 0.6675427602585322 1.0 0.9455569195356492 2 A6NHR9 1 +Dwarfism 0.4626340587929092 0.4218858816978634 0.6731083156016486 1.0 0.9455569195356492 51 Q8WVQ1,Q96HY6,P34059,O43909,Q32P28,Q96ST3,Q96PZ0,Q14739,O95831,P40763,Q13472,Q9UQR1,Q15125,Q7LBC6 14 +Zellweger syndrome 0.425503101125688 0.3911998253765109 0.6956495373715066 1.0 0.9544958768585788 5 P40855,P56589 2 +Peroxisome biogenesis disorder 0.425503101125688 0.3911998253765109 0.6956495373715066 1.0 0.9544958768585788 5 P40855,P56589 2 +Alport syndrome 0.4039539687223327 0.3415819515344114 0.7326655216710463 1.0 0.97861662746645 2 P35579 1 +Hermansky-Pudlak syndrome 0.3875442739079135 0.2740330432596816 0.7840592283992043 1.0 0.97861662746645 3 O00203,Q86YV9 2 +Albinism 0.3875442739079135 0.2740330432596816 0.7840592283992043 1.0 0.97861662746645 3 O00203,Q86YV9 2 +Ectodermal dysplasia 0.3969277112680198 0.2676959097132312 0.7889333985218605 1.0 0.97861662746645 7 Q9H1A4,P61586 2 +Charcot-Marie-Tooth disease 0.4210851774979489 0.2402063108382531 0.8101703215475613 1.0 0.97861662746645 23 P54802,Q6UWE0,O95831 3 +Hereditary spastic paraplegia 0.3861710450997933 0.1689245198447201 0.8658560123047481 1.0 0.97861662746645 15 Q15041,Q9NQ11 2 +Dystonia 0.3655796827765973 0.160286739594938 0.8726552040926316 1.0 0.97861662746645 8 Q9BV79 1 +Leukodystrophy 0.3912900305088107 0.146252818288572 0.8837218108169289 1.0 0.97861662746645 21 P07602 1 +Diabetes mellitus 0.366088522082876 0.1382736626238462 0.8900241397241793 1.0 0.97861662746645 11 P31751 1 +Obesity 0.3249391329559123 0.0605461530865936 0.95172065840002 1.0 1.0 8 O15078,Q9ULH0,Q9C0B1 3 +Amyotrophic lateral sclerosis 0.3367799071929546 0.0441979068287484 0.9647466505334736 1.0 1.0 14 Q99720 1 +Microphthalmia 0.3117747524216692 0.0423385491939609 0.9662288150110436 1.0 1.0 7 Q6W2J9 1 +Epilepsy 0.3559845189387521 0.0165380668098389 0.9868051333124832 1.0 1.0 72 Q14108,Q13510,Q93063,O75503,O43567,O14773 6 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..addfe940eeb1c3709df37faa42f3e4da3f830874 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABHD11", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKAP12", "AKR1B1", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOB", "APOL2", "APP", "APPL1", "APRT", "ARAF", "ARCN1", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARV1", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP11C", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5D", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "ATXN10", "AURKB", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLMH", "BMS1", "BOLA3", "BPTF", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNB2", "CCNK", "CCT5", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDKAL1", "CEP135", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "COA7", "COASY", "COG6", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ9", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DAPK3", "DARS", "DARS2", "DBN1", "DBT", "DCAF8", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEGS1", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DTNA", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFNB1", "EFTUD2", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELL", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENPP1", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTB", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI3", "GNAQ", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GRB2", "GSK3A", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HOXD11", "HOXD13", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF1R", "IGF2R", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3BP", "LGMN", "LIPA", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRP2", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MATR3", "MBD1", "MBNL1", "MBOAT7", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED17", "MED23", "MESD", "MFGE8", "MFN2", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMACHC", "MMADHC", "MOCS1", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NEO1", "NEU1", "NF1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NR2F1", "NSD1", "NSD2", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUS1", "NXN", "OARD1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OTUD6B", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARK7", "PARN", "PARP1", "PARP2", "PATZ1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD4", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDXK", "PEPD", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23B", "RALGAPA1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBMX", "RDH11", "RDX", "REEP6", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RMND1", "RNASEH2A", "RNASET2", "RNF13", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RRM2B", "RTN2", "RTN4IP1", "RUFY3", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SIAE", "SIGMAR1", "SIL1", "SIN3A", "SIRT2", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC3A2", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKT", "TMCO1", "TMEM106B", "TMEM126B", "TMEM165", "TMEM230", "TMEM38B", "TMEM43", "TMEM63A", "TMEM70", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TP53RK", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXN2", "TXNL4A", "TXNRD1", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR34", "WDR36", "WDR5", "WNK1", "WRAP53", "XIAP", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "YY1", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2", "ZNF148", "ZNF644"], "leading_proteins": ["ABCB1", "ACTN1", "ACVR1B", "ADAMTS1", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ANAPC1", "ANXA1", "AP3B1", "APOB", "APP", "ARIH1", "ARL6IP1", "ARMC9", "ASAH1", "ATP11C", "ATP13A2", "ATP6AP1", "ATP6AP2", "ATP7A", "ATP7B", "B4GAT1", "BCOR", "BICD2", "BLMH", "BUD23", "C1QBP", "CANT1", "CAPN1", "CARM1", "CCDC6", "CDH2", "CDK1", "CEP290", "CHST14", "CLCN7", "CLN5", "CLN6", "COX15", "COX2", "CSNK2A2", "CTNNBL1", "CTSA", "CTSB", "CTSC", "CUL4B", "DCTN1", "DDRGK1", "DHCR24", "DHCR7", "DHFR", "DIAPH2", "DICER1", "DNAJB11", "DNAJC2", "DSC3", "DSG2", "DTNA", "EARS2", "EBP", "ECE1", "EHMT1", "EIF2B5", "EIF4H", "ELP2", "EPHA7", "ERGIC1", "ETNK1", "EXT2", "EXTL3", "EZR", "FAF1", "FKBP1A", 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6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 6.943379172874626e-08 4.844157765872774e-05 2.0597753624715522e-07 2.0114332489481176e-05 0.0005289198821125 +Protease 17 89 2.728632269008364 0.0063597579560772 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 1.7578619331494042e-07 1.4076449696608436e-05 2.749780419421069e-07 3.192289350601833e-06 1.812609067392853e-05 +Glycosidase 15 21 2.4537496976878166 0.0141375349138468 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 1.0535467292748975e-09 1.9327312747144497e-06 2.074822650532168e-10 3.3418244427413275e-14 5.894684740377531e-11 +Protease inhibitor 1 7 2.4187876669362733 0.0155723271758663 2.679611650485437 6.827669902912621 -0.1389909380340853 0.4401686430319619 1.73744367643855 1.203518872907143 1.1014803254493444 0.2988298098237953 0.0158457649983195 0.0065792573185243 0.0237627189197599 0.1227655047468798 0.3442759855295882 +Heparin-binding 5 9 2.364422403147202 0.0180582098972486 2.3567961165048543 6.854368932038835 0.2151021415291715 0.4976817002921777 1.5599282492786453 1.096399818915653 1.0317858467489989 0.3203044603738155 0.0010237530657933 0.1201219647894398 0.0019068669696529 0.0033507773717699 0.0012730265791845 +Muscle protein 4 8 2.1206481740626244 0.033951420884472 2.395631067961165 5.79126213592233 0.1338245975855889 0.4297267356278353 1.4112173151187923 1.0428309859537837 1.1380106971522683 0.3003044609278026 1.0 1.0 1.0 0.0768284795296569 0.0118865434534573 +Receptor 26 47 2.018402265943011 0.0435493835959397 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0031637763726274 0.0001988835377557 0.0001382641464135 0.0001264234660949 7.917128778825581e-05 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eeacc15ce6a96bc9020efdd23315a1ff1682b43a --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 93, + "title": "Average number of proteins per term", + "value": 42.333333333333336 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4439bfc7c9075164e197ab06ccedf6e171c35de2 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1a09c9997cb7e1d325447baa3836bde0fa822466 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Hydrolase 0.4424447906981131 4.073609138519247 4.629014401258402e-05 0.0042958294493399 0.0043049833931704 411 P07858,P34059,Q9UQ16,Q9UIQ6,P17900,P04062,Q8N6M0,P16278,Q16706,P42892,Q9BW91,O14773,O75976,O00584,Q9H3G5,Q9UMR5,P38571,Q9NZ08,P07384,Q9NP77,Q01459,Q9UJ14,P04066,Q8NHP8,P06280,Q99538,P06865,P08236,P11117,Q9HB40,Q9BTY2,P68402,P54802,P50897,P15586,P53634,Q9HAT2,P10253,Q8TCT8,Q8IV08,Q92820,P10619,Q13510,P07686,Q9NX62,Q9UHI8,P42785,O43598,Q8NCC3,O00462,Q6P179,Q99519,Q8WVQ1,Q9HB07,Q9BYT8,O00754,O14657,Q13572,P17655,Q9UN37,P28074,P28072,Q96L91,Q05D32 64 +Chloride channel 0.9528005104066116 2.7740929864160098 0.005535585337361 0.403239609721058 0.0591919565926798 4 Q9H813 1 +Carboxypeptidase 0.9536980071327522 2.7731643691700594 0.0055514072762488 0.4041219489480619 0.0591919565926798 6 O75976,P10619,Q9HB40,Q9H3G5 4 +Protease 0.6000683193748775 2.7286322690083633 0.0063597579560772 0.4475245414639894 0.0591919565926798 89 Q8TCT8,Q6P179,P07858,P10619,Q99538,Q9UIQ6,Q9HB40,P42892,O14773,O75976,Q9UHI8,Q9H3G5,P42785,P53634,P17655,P28074,P28072 17 +Serine protease inhibitor 0.9320498520153656 2.687328197878767 0.0072026143822621 0.4894501999875243 0.0608948306863978 4 P05067 1 +Integrin 0.8866587957497039 2.4985408524139854 0.0124705768008797 0.6887179272598882 0.0883901852865326 3 P06756,P23229 2 +Glycosidase 0.8756660805363883 2.4537496976878166 0.0141375349138468 0.7339771927004852 0.0883901852865326 21 O00462,Q01459,Q99519,P04066,P06280,P06865,P04062,P08236,O00754,P16278,Q9BTY2,P07686,P54802,O43598,P10253 15 +Threonine protease 0.8730171756676008 2.439963732221234 0.0146887365045584 0.7474597479060412 0.0883901852865326 3 P28074 1 +Protease inhibitor 0.8714924352854888 2.4187876669362733 0.0155723271758663 0.767675691831828 0.0883901852865326 7 P05067 1 +Heparin-binding 0.8600588640984066 2.364422403147202 0.0180582098972486 0.8163571025256366 0.0883901852865326 9 P51858,P04114,P05067,Q9UHI8,O94813 5 +Muscle protein 0.8053559142259478 2.1206481740626244 0.033951420884472 0.9597372119398082 0.1563958940558231 8 P09493,P60660,P14649,P67936 4 +Receptor 0.7369360677955868 2.018402265943011 0.0435493835959397 0.9840919378515364 0.1840951215646543 47 Q15375,P05556,Q99523,P30825,O15118,P98164,O75787,P08069,P11717,Q9Y624,P02786,P10586,Q07954,Q5KU26,Q14108,Q8WTV0,Q9UBG0,P20645,P78310,P36896,P23229,P11279,O43731,P06493,Q99720,P06756 26 +Host cell receptor for virus entry 0.7570424911502618 1.8800539162755217 0.0601007302002316 0.9968626567628444 0.2235747163448617 16 P05556,P06756,P11279,O15118,Q14108,Q8WTV0,P78310,Q9Y624,P02786 9 +Metalloprotease 0.7154157446364023 1.6910921093626463 0.0908192120129527 0.99985728380716 0.2815395572401535 27 Q6P179,Q9UIQ6,Q9BYT8,P42892,O75976,Q9UHI8,Q9NZ08 7 +DNA-directed DNA polymerase 0.6931396670368248 1.6166801788824638 0.1059473346154775 0.9999700243568702 0.3079094412262316 5 P54098 1 +Aminopeptidase 0.6726307504678889 1.4802692776572683 0.138801398693213 0.9999990782601376 0.368815145099109 12 Q9UIQ6,Q6P179,Q9NZ08 3 +Ion channel 0.6642497115144893 1.4394531998359408 0.1500221606463656 0.999999727788122 0.3875572483364446 12 Q9H813 1 +Transducer 0.640146033417623 1.3322364411119807 0.1827825053679839 0.9999999929627668 0.4473361315584869 10 P02786 1 +Developmental protein 0.3958341669132681 0.7920101445143211 0.4283547611488973 1.0 0.7967398557369492 89 Q15375,Q9BY67,Q99523,P31751,Q13555,Q96N67,P31749,A0MZ66,Q16527,Q8NB78,Q92520,Q13685,Q16352,P29375,Q9ULC3,Q96EK5,O94813,Q07954 18 +Tumor antigen 0.5100329231307112 0.7522576975153689 0.4518961020110581 1.0 0.8081987978274694 5 Q9UNF1,Q8ND90 2 +Glycosyltransferase 0.5253905006028573 0.7123543230118002 0.4762453929357766 1.0 0.8199044405683519 40 O60512,Q16739,Q86SF2,O43909,P04062,Q93063,P15291,Q10472,Q10471,O43505,Q11206 11 +Tyrosine-protein kinase 0.5015243071623963 0.6856766457369476 0.4929170370292228 1.0 0.8199044405683519 8 Q15375 1 +Calcium channel 0.4850988492180625 0.6720322203842959 0.5015631844215691 1.0 0.8199044405683519 2 Q8NE86 1 +Thiol protease 0.518068293138709 0.6567553266184543 0.5113382532576818 1.0 0.8199044405683519 33 Q13867,P07858,Q99538,Q8N6M0,Q9Y4E8,P17655,P53634,P07384 8 +Serine protease 0.4819056762191318 0.5889878705254797 0.5558694103529755 1.0 0.8502700665666002 9 O14773,Q4J6C6 2 +Myosin 0.4428992895713426 0.4144923666774388 0.678513556197208 1.0 0.9973312932046914 10 P14649 1 +Kinase 0.2636002580305804 0.1840245034876546 0.8539942321840166 1.0 1.0 115 Q15375,Q8TD19,O15111,O75414,O43252,P08069,Q16539,Q8TBX8,Q9HBU6,P19784,O43293,P36896,P53350,P55263,Q13555,Q96KB5,P31751,Q9HA64,P06493,P31749,Q13572 21 +Guanine-nucleotide releasing factor 0.3827081677976945 0.1725428646821642 0.863010765497757 1.0 1.0 13 P80303,Q96N67,Q02818 3 +Lyase 0.4007539766730811 0.1004368495894037 0.9199975159174518 1.0 1.0 44 Q8NBZ7,P61457,Q8WUX2,P19021,O00584 5 +Dioxygenase 0.3445942925177275 0.0485392211840058 0.9612865072798816 1.0 1.0 16 P13674,Q9C0B1,Q32P28,O15460,Q7LBC6 5 +Translocase 0.3660576033441169 0.028668320310731 0.9771291227073442 1.0 1.0 29 Q9NQ11,P35670,O75489,Q04656,Q13423,P00403,P08183,Q8NB49,P23634 9 +Nuclease 0.3692980501621395 0.0126066948828154 0.9899415792196716 1.0 1.0 35 Q9BQP7,Q8IV08,Q9HB07,O00584,Q15631 5 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9b72ddd75070baf40099a8c5ecd09cc25c57ed2d --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "ANKHD1", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APLP2", "APOB", "APOBEC3C", "APP", "APRT", "AQR", "ARAF", "ARFGAP1", "ARFGAP2", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7A", "ATP7B", "ATRX", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT1", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BSG", "BTF3", "BTRC", "BUB1B", "BUD23", "BZW1", "BZW2", "C10orf88", "C11orf54", "C12orf43", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBR1", "CBR4", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCDC85C", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CEP290", "CERS1", "CERS2", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSB", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DRAP1", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EFNB1", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTB", "FOXK1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGT7", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPAM", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXA", "HEXB", "HIBADH", "HIBCH", "HIC2", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOXD11", "HOXD13", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "L3HYPDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED1", "MAGED2", "MAN2A1", "MAN2B1", "MANBA", "MAP1S", "MAP2K1", "MAP2K2", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MATR3", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFN1", "MFN2", "MGEA5", "MGME1", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCEH1", "NCL", "NCOA5", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NEU1", "NF1", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOCT", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUS1", "NXF1", "NXN", "OARD1", "OAT", "OCRL", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD6B", "OTULIN", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDRG1", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMF1", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMD9", "PSME4", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD50", "RAI1", "RALA", "RALB", "RALGAPA1", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOK2", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP8", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUFY3", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD5", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPCS2", "SPCS3", "SPEN", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRGAP2", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "ST3GAL4", "STAT1", "STAT3", "STAU1", "STAU2", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TERF2", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TMCO1", "TMEM109", "TMEM126B", "TMEM206", "TMEM38B", "TMEM63A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "WARS", "WARS2", "WASF2", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WRAP53", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF3", "YY1", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC3", "ZFR", "ZMPSTE24", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZRANB2"], "leading_proteins": ["AAMP", "ABCB1", "ACP2", "ACVR1B", "ADAMTS1", "ADK", "AKT1", "AKT2", "APOB", "APP", "ASAH1", "ATP11C", "ATP13A2", "ATP2B4", "ATP6AP2", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "B4GAT1", "BLMH", "CADM1", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CDK1", "CHAC2", "CHUK", 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3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 1.788817545860639e-11 4.9564805449305045e-09 2.3212022465033123e-14 3.374023412421456e-16 9.290934442859482e-15 +Transporters 100 405 4.348825643642205 1.3686847068594687e-05 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 0.0018658973270741 0.0004208511408673 5.67823517839768e-06 2.949994570591942e-09 1.1886946730332983e-09 +Potential drug targets 105 520 3.13324067080197 0.0017288761809743 97.55339805825244 482.2839805825243 0.1164506319746192 0.6956405557980175 32.086496616991845 44.65677560523076 1.054724020710321 0.3686644405287784 3.0766431624647565e-08 5.062854727079051e-05 3.1974198382374046e-10 1.6448183120948112e-09 4.484191856750869e-09 +CD markers 15 20 2.1657848708331366 0.0303276299781412 6.548543689320389 16.62378640776699 0.159361413045758 0.3347758559744795 3.625700175504636 4.1209525283344535 1.5119526885132668 0.3016304730463651 0.009431186810905 0.0154102901166228 7.270369264469176e-05 0.0002682587329165 5.399943600117159e-05 +Predicted secreted proteins 23 60 2.0792281375481307 0.037596386610091 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 9.451641825447244e-07 5.261862373040465e-06 2.5384351480382044e-07 3.550943941057001e-08 0.0001117712546419 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..49a19d9ff39a15cfae7da158e9d93db74feaa2c7 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3391, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 516.6190476190476 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ad1c3c0d143318670d0bb5b33e91fd319ed74f0 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C281/C281_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a08fbec38d72bcdc290a5d12ace2f8127e635f70 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,14 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.4951572019849265 5.6115081139984335 2.0057088198482865e-08 4.211987677089256e-07 4.211988521891402e-07 633 Q9H813,Q6UXD5,Q99523,Q8NC54,Q9C0H2,Q9UIQ6,O60637,P05067,Q13641,Q15392,P98164,P42892,Q06481,O75976,Q9Y287,O75071,P11717,Q92859,P02786,Q07954,Q9H2J7,Q8IZA0,Q14574,Q5KU26,O43493,Q14108,P11117,Q9HBU6,Q8NBN3,Q9UBG0,P19021,Q92896,P53634,Q15904,Q8NCH0,O94813,Q9NPR9,Q8TCT8,Q9BY67,Q8IV08,P51790,P13473,P11279,Q7L0J3,Q8IXU6,Q9NX62,P43121,O43567,Q9NWW5,P27105,Q5VW38,Q11206,Q99720,Q8NCC3,Q8WVQ1,Q9NQ11,P35670,Q93063,Q9P0I2,Q96GC9,Q5BJF2,Q92542,Q08722,Q15375,P10321,Q8IYS2,P08195,Q9NX00,O15118,Q96IX5,Q13190,Q9NRB3,Q6ZRP7,O43752,Q9Y624,Q99805,Q9HBM0,P21359,O60830,O00461,Q8WTV0,Q92544,Q10472,P01889,Q9GZT8,P78310,Q15070,Q14126,Q9HD45,P36896,Q93050,Q9UBM7,O43674,Q9NV96,O43731,P15291,Q6P4A7,O15260,Q5SW79,O15400,P04439,Q16739,P09493,Q15041,Q96N66,Q9NUM4,Q567V2,Q13277,Q9UBX3,Q04656,Q16706,Q5SQN1,Q86V85,P08069,Q9UJ14,O43909,Q9BU23,Q13423,P51797,O43293,P20645,Q8ND04,Q99595,P23229,Q8TAA9,Q9Y282,Q9Y487,Q9H3K2,P62942,O95772,Q86Y82,Q8TAD4,Q5JRA6,Q15125,Q6NUK4,Q96G23,Q9NWR8,P06756,P19022,P51798,Q3SXM5,Q9Y2W6,Q9Y6C9,O95831,Q5SWX8,O15126,P05556,P30825,Q14728,Q7KZN9,Q9UH99,P51648,O75787,P08183,Q969X5,P10586,O95168,Q12907,Q6NT16,Q8IXM6 160 +Transporters 0.4573921247531969 4.348825643642205 1.3686847068594687e-05 0.0002873844525959 0.0001437118942202 405 Q9H813,Q8TD19,Q99523,P07602,P56589,Q9C0H2,P54709,O60637,O60313,P05067,P98164,Q9Y287,P23634,O00410,P11717,P02786,Q07954,Q9H2J7,Q8TEX9,Q9Y5K6,Q14108,Q15904,Q8TCT8,P13473,P11279,Q8IXU6,P61916,Q9NWW5,P27105,Q9UHI8,Q5VW38,Q99720,Q9NQ11,P35670,P31749,Q9P0I2,Q96GC9,Q5BJF2,Q9BRK5,Q08722,P08195,O15118,Q13190,O43752,Q99805,Q9HBM0,Q8WTV0,Q92544,P78310,Q15070,Q07021,Q93050,P04083,Q9NV96,Q6P4A7,O15260,P04439,Q16739,Q96N66,Q9NUM4,O00560,O60645,Q13277,Q9UBX3,Q04656,P20645,O60784,P23229,Q8TAA9,P61421,P62942,P40855,Q8TAD4,Q5JRA6,Q9NWR8,P06756,P46934,O75955,P51798,Q9Y6C9,O15126,P05556,P30825,Q8TAG9,Q9UH99,O75787,P08183,Q6NT16,Q8NB49,Q70HW3,Q13555,P06493,P00403,P41440,O14828,Q8IY95,P29992,O75915,O75844,Q99643 100 +Potential drug targets 0.3802714777973434 3.13324067080197 0.0017288761809743 0.0356855268958871 0.0121021332668207 520 Q8TD19,P07858,Q99523,Q10713,P07602,P34059,P56589,Q04446,Q15392,P98164,P42892,O14773,O00584,Q9Y287,Q07954,P04066,P06280,P06865,Q14108,P11117,P54802,P50897,P15586,P53634,Q15904,Q9HAT2,Q8NCH0,Q8IV08,P10619,P13473,Q13510,P07686,Q9NX62,P61916,O43567,Q9NWW5,P48449,O00462,Q99519,Q8WVQ1,Q9NQ11,Q9BV79,P35670,Q93063,O00754,P31749,O15118,P04062,Q8N6M0,P16278,P38571,P28070,P08236,P61457,P36896,Q07021,Q9UBM7,P31751,P15291,Q6P4A7,P04439,Q96N66,Q9NUM4,Q10471,Q6UWE0,Q04656,O15460,P07384,Q5JPH6,O43909,Q9NQX3,Q13472,P23229,Q8TAA9,Q9Y4U1,P40855,Q9H2U2,Q7LBC6,O96028,Q15125,P51798,P35270,Q13126,Q4J6C6,O15111,P51648,O75787,P10586,Q9C0B1,O43464,P22695,Q8NB49,Q70HW3,P11413,P53350,Q13555,Q9UPY3,Q32P28,P00403,Q96RR1,P54098,P29992,P29375,O75844,Q99643 105 +CD markers 0.8155616968570176 2.1657848708331366 0.0303276299781412 0.4762483070946027 0.127376045908193 20 Q08722,P23229,P05556,P08195,P13473,P11279,P06756,P19022,P43121,Q9UBG0,P08069,P11717,Q9Y624,P02786,Q07954 15 +Predicted secreted proteins 0.6978178487662823 2.0792281375481307 0.037596386610091 0.5527996413329389 0.1315873531353185 60 P07858,P05067,Q92520,O00584,Q9Y287,Q08431,O75629,P02786,Q9HB40,Q9BTY2,P19021,P78310,Q08380,Q07021,O94813,P04083,P04114,P61916,Q9UHI8,Q6P179,O60888,Q9UM22,P80303 23 +Candidate cardiovascular disease genes 0.6970680929679773 1.60263574053321 0.1090150981927782 0.9114319179850516 0.2861646327560428 11 P06865,P07858,P04114,Q07954 4 +Cancer-related genes 0.3097992361271933 1.2559921562821543 0.2091188139345114 0.9927500312804872 0.4391495092624741 393 P07858,Q9UNF1,Q9NVC6,Q96ST3,Q08431,P11717,Q92859,P02786,P15311,O95071,Q99538,Q9HBU6,Q13620,P61586,P33993,P00390,Q08380,Q8WYA6,Q9UHI8,Q86X55,Q8WVQ1,P35670,Q93063,P31749,P80303,Q15375,P08195,P21359,Q93074,P08236,P01889,P36896,Q07021,P04083,P31751,P67809,P04439,P00374,Q9UDY2,Q01105,P09493,P10644,Q15056,P40763,Q99543,Q9BZK7,Q16204,P08069,Q16539,Q9NQX3,P68402,Q13472,Q99595,O60784,P23229,P62258,Q9H2U2,O96028,P06756,P31946,O60934,P05556,Q8IWS0,P08183,P67936,P19784,P11413,P53350,Q9UPY3,P06493,Q14203,P41440,Q13867,Q9UNN5,Q04917,P29992,P29375,Q99643 78 +Human disease related genes 0.3023051903197912 1.191550274632922 0.2334376325023217 0.996237319080028 0.4456536620498869 988 Q8TD19,P07858,Q69YQ0,Q10713,P07602,P34059,Q04446,P56589,O60313,P17900,P05067,Q9UNF1,Q15392,O75503,P98164,P42892,Q9UBS4,O14773,Q9NVC6,O00584,Q9Y287,Q96ST3,Q14739,Q9Y3D3,P49591,Q14574,P04066,P17480,Q96HY6,P06280,Q9Y5K6,Q9Y4J8,P06865,Q14108,P11117,Q9HBU6,Q9H3S7,Q13620,P61586,P54802,P12814,P50897,P15586,Q9Y6M1,Q9NX24,P53634,Q96MW5,P10253,Q8NCH0,Q8NC96,Q9BY67,Q8IV08,P55263,P10619,Q9Y467,P13473,Q9Y263,Q9BQE5,O94886,Q13510,P07686,Q9NX62,P61916,O43567,Q9NWW5,O43505,Q99720,P48449,O00462,Q99519,Q8WVQ1,Q9NQ11,Q9BV79,P35670,Q93063,O00754,P31749,Q92542,P10321,Q8TD16,Q9H0U9,O15118,P04062,Q96IX5,Q8N6M0,P16278,Q9H173,P38571,P21359,Q9Y6B6,Q93074,P08236,P61457,P01889,Q14126,Q07021,Q9UBM7,P04114,P31751,P15291,Q6P4A7,Q96PZ0,P04439,P00374,Q9UDY2,Q01105,P09493,P10644,Q15041,Q96N66,Q15056,Q9NUM4,Q10471,P40763,Q6UWE0,Q9NVU7,Q9BZK7,Q9UBX3,Q04656,O15460,Q16204,P08069,Q96EK5,P07384,Q5JPH6,P62857,O43395,O43909,Q9NQX3,Q13423,Q13472,Q14671,P23229,Q8TAA9,P62258,Q9Y487,Q9Y4U1,P40855,P23258,O96028,Q15125,Q9BQP7,P19022,Q6IA86,P51798,O14949,O60934,P35270,O95831,Q4J6C6,O15111,Q7KZN9,Q96N67,Q9H9B1,Q8IWS0,P51648,O75787,P08183,Q9UQR1,Q969X5,Q9H490,Q9C0B1,O43464,P22695,Q70HW3,P11413,Q8N183,Q15555,O43292,Q13144,Q13555,Q9UPY3,Q5XKP0,Q32P28,P00403,O60333,Q7Z3E5,Q9ULC3,Q15427,O43709,Q14203,Q96RR1,P54098,O96000,Q9GZZ9,P46020,P29992,O75844,Q9H9S5,Q99643 190 +Disease related genes 0.2912977977922822 0.8550725949038768 0.3925109600949634 0.9999715352491944 0.6234803406236608 1093 Q8TD19,P07858,Q99523,Q69YQ0,P07602,P34059,Q10713,Q04446,P56589,P17900,P05067,O60313,Q15392,O75503,P98164,P42892,Q9UNF1,O14773,Q9UBS4,O00584,Q9Y287,Q9NVC6,Q96ST3,Q14739,Q9Y3D3,P02786,Q07954,Q9BUF5,P49591,Q14574,P04066,P17480,Q96HY6,P06280,Q9Y5K6,Q9Y4J8,P06865,Q14108,P11117,Q9H3S7,Q13620,P61586,P54802,P12814,P00390,P50897,P15586,Q9Y4X5,Q9NX24,P53634,Q15904,Q9HAT2,P10253,Q8NCH0,Q96MW5,Q8TBA6,Q8NC96,P55263,Q8IV08,P10619,Q9Y467,P13473,Q9Y263,O94886,Q13510,P07686,Q9NX62,P61916,O43567,Q9NWW5,O43505,Q99720,P48449,O00462,Q99519,Q8WVQ1,Q9NQ11,Q9BV79,P35670,Q93063,O00754,P31749,Q92542,P10321,Q8TD16,Q9H0U9,O15118,P04062,Q96IX5,Q8N6M0,P16278,Q9H173,P38571,P21359,Q9Y6B6,P28070,Q93074,P08236,P61457,P01889,Q14126,P36896,Q07021,Q9UBM7,P04114,P31751,P15291,Q6P4A7,Q8NDZ4,Q96PZ0,P04439,P00374,Q9HB07,Q9UDY2,Q01105,P09493,P10644,Q15041,Q96N66,Q15056,Q9NUM4,Q10471,P40763,Q6UWE0,Q9BZK7,Q04656,O15460,Q16204,P08069,Q96EK5,P07384,Q5JPH6,P62857,O43395,O43909,Q9NQX3,Q13423,Q13472,Q14671,P23229,Q8TAA9,Q9Y487,Q9Y4U1,P40855,P23258,Q9H2U2,Q7LBC6,O96028,Q15125,Q9BQP7,Q6IA86,P51798,O14949,O60934,P35270,Q13126,O95831,Q4J6C6,O15111,Q7KZN9,Q96N67,Q9H9B1,Q8IWS0,P51648,O75787,P08183,Q9UQR1,Q969X5,P10586,Q9H490,Q9C0B1,O43464,P22695,Q8NB49,Q70HW3,P11413,Q8N183,Q15555,P53350,O43292,Q13144,Q13555,Q9UPY3,Q5XKP0,Q32P28,P00403,O60333,Q7Z3E5,Q9ULC3,Q15427,Q14203,Q96RR1,P54098,Q9GZZ9,P46020,P29992,P29375,O75844,Q9H9S5,Q99643 200 +FDA approved drug targets 0.3124077858440838 0.8139849715693298 0.4156535604157738 0.9999874084716714 0.6234803406236608 125 P00374,P04083,Q16739,P06756,P49721,Q7L0J3,P05067,P62942,Q13423,P23258,P20645,P08069,P28074,P10253,Q99720,P02786 16 +Enzymes 0.2816427788645154 0.4399468853148572 0.6599755771312132 0.999999999854885 0.8152639482209104 977 P07858,P34059,Q9UIQ6,Q15392,P42892,O14773,O75976,O00584,Q9H3G5,P02786,P04066,P06280,Q99538,P06865,P11117,Q9HBU6,Q9HB40,Q9BTY2,P54802,P19021,P50897,P15586,P53634,Q9HAT2,P10253,Q8NCH0,Q8TCT8,Q8IV08,Q92820,P10619,Q8NBZ7,P49721,Q13510,P07686,Q9NX62,Q5VTR2,O43567,P42785,Q86X55,Q11206,P48449,Q8NCC3,O00462,Q6P179,Q99519,Q8WVQ1,Q9BV79,P35670,Q93063,O00754,P31749,Q13572,P17655,P28074,P28072,Q15375,P04062,Q8N6M0,P16278,Q9NRB3,Q6ZRP7,P38571,Q9Y237,O60512,P28070,Q86SF2,P08236,Q8TBX8,P61457,Q10472,P36896,Q9UBM7,P31751,Q8N4Q0,Q9HA64,Q9P2E5,O95251,P15291,Q8WUX2,P60604,Q86UY6,P00374,Q16739,Q9BYT8,Q10471,Q9UN37,Q6UWE0,Q6YP21,Q9UQ16,Q04656,O15460,Q16706,Q9BW91,P08069,Q9NZ08,P07384,Q9NP77,Q9UJ14,Q5JPH6,Q16539,O43909,Q9Y697,Q9NQX3,Q9Y680,Q13423,P68402,O43293,P55786,Q13472,Q9UNP9,Q8N1G2,Q9Y4U1,P62942,Q8NB78,Q9H2U2,Q7LBC6,Q00403,O96028,Q15125,Q96G23,Q9UHG3,P46934,P13984,Q9UHY1,P35270,Q13126,Q4J6C6,O15111,O75414,Q9C0C9,P51648,P08183,P10586,P13674,Q9C0B1,O43464,P22695,P19784,Q9Y4E8,Q9UBP6,Q8NB49,P19623,P11413,Q8IU81,Q96HS1,P53350,Q13555,Q9UPY3,Q9BWD1,Q32P28,P49720,P06493,P00403,Q9Y2Q3,Q7L5Y9,O60841,P34896,Q13867,Q9H8M7,Q96RR1,P54098 161 +Metabolic proteins 0.2771607769630349 0.2232400535948221 0.8233486801521392 1.0 0.9605734601774958 949 P07858,P07602,P34059,P17900,Q15392,P98164,O14773,Q9UMR5,P02786,Q9H2J7,P04066,P06280,Q99538,P06865,P11117,Q9HBU6,Q9BTY2,P54802,P19021,P50897,P15586,P53634,Q15904,Q9HAT2,P10253,Q8NCH0,Q7LGA3,Q8IV08,Q92820,P10619,Q8NBZ7,Q13510,P07686,Q9NX62,Q5VTR2,O43567,Q86X55,O43505,Q11206,P48449,Q8NCC3,O00462,Q99519,Q8WVQ1,Q9BV79,Q93063,O00754,P31749,Q13572,Q05D32,Q15375,P08195,O15118,P04062,Q96IX5,P16278,Q9NRB3,P38571,Q9Y237,O60512,Q86SF2,P08236,Q8TBX8,Q8WTV0,P61457,Q10472,P36896,Q93050,Q9UBM7,O43674,P04114,P31751,Q8N4Q0,Q9HA64,Q9P2E5,O95251,P15291,P60604,Q86UY6,P00374,Q9NXR7,Q16739,Q9BYT8,P10644,Q96N66,Q10471,Q6UWE0,Q6YP21,Q9BZK7,Q9UBX3,Q9UQ16,O15460,Q16706,Q9BW91,P08069,Q9NP77,Q9UJ14,Q16539,O43909,Q9NQX3,Q9Y680,Q13423,P68402,O43293,P55786,Q9UNP9,Q8N1G2,P61421,Q9Y487,P62942,Q9H2U2,Q5JRA6,O96028,Q15125,Q96G23,Q9UHG3,P46934,O14949,P35270,Q13126,A6NJ78,O15111,O75414,P30825,Q9C0C9,Q9H9B1,P51648,P08183,Q13564,P10586,O95168,P13674,Q9H490,P22695,P19784,Q9Y4E8,Q9UBP6,Q9NRF9,Q8NB49,Q70HW3,P19623,P11413,Q96HS1,P53350,O43292,Q13555 146 +RAS pathway related proteins 0.3797499953007199 0.0637189215053223 0.949194038179536 1.0 1.0 30 P21359,O15111,P31751,P11234,P31749,P61586,Q9UBI6,P08069 8 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f3ab9c15177357fe54d1ff65125dfad0d6cb74ba --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAMTS1", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKS1A", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOB", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARAF", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARHGAP17", "ARHGAP35", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL5B", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP13A2", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5D", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7A", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKB", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCLAF1", "BCOR", "BCS1L", "BET1", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOLA3", "BOP1", "BPHL", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSG", "BTF3", "BTRC", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf88", "C11orf54", "C12orf29", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C20orf27", "C2CD2L", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CASP2", "CASP3", "CASP7", "CBFB", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC138", "CCDC167", "CCDC22", "CCDC47", "CCDC6", "CCDC85C", "CCDC86", "CCDC94", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD3EAP", "CD47", "CDC123", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK2AP1", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPO", "CENPP", "CENPV", "CEP135", "CEP170", "CEP250", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHRAC1", "CHST12", "CHST14", "CHTF8", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLINT1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA7", "COASY", "COG3", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREG1", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTBS", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CTTNBP2NL", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DAPK3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND6A", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENPP1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA7", "EPHX1", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EXTL3", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GGT7", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM2", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIF7", "KIFBP", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPCAT3", "LPGAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8B", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAP7D1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "METTL3", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPRIP", "MPST", "MPV17L2", "MRC2", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF2", "MTERF3", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYL6B", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2AS2", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT12", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PAXX", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PDZD11", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNISR", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11FIP1", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALB", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP3", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RMND1", "RMND5A", "RNASEH2A", "RNASET2", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF2L1", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHTN1", "SIAE", "SIGMAR1", "SIL1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "SSU72", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TACC3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM206", "TMEM214", "TMEM230", "TMEM245", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM63A", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TP53RK", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WIZ", "WNK1", "WRAP53", "WRAP73", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ACAT2", "ACP2", "ACTN1", "ACVR1B", "ADAMTS1", "ADK", "AIFM1", "AKT1", "AKT2", "ALDH3A2", "ANXA1", "APLP2", "APOB", "APOL2", "APP", "ARIH1", "ARL6IP1", "ARL6IP5", "ARMC9", "ASAH1", "ATP11C", "ATP13A2", "ATP1B3", "ATP2B4", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BICD2", "BLMH", "BUD23", "C19orf70", "C1QBP", "C3orf58", "C5orf15", "CADM1", "CAMK2G", "CANT1", "CAPN1", "CAPN2", "CARM1", "CCDC6", "CD2AP", "CD47", "CDH2", "CDK1", "CEP170", "CERS2", "CHAC2", "CHPF2", "CHST12", "CHST14", "CHUK", "CLCN3", "CLCN6", "CLCN7", "CLN5", "CLN6", "CMTR1", "COG8", "COLEC12", "COX15", "COX2", "CPD", "CPVL", "CREG1", "CSNK2A2", "CTDSPL2", "CTNNBL1", "CTSA", "CTSB", "CTSC", "CUL4B", "CUTA", "CXADR", "DAPK3", "DCTN1", "DDRGK1", "DHCR24", "DHCR7", "DHFR", "DICER1", "DNAJB11", "DNAJC2", "DNM3", "DOCK7", "DSC3", "DSG2", "DTNA", "EARS2", "EBP", "ECE1", "EFCAB14", "EHMT1", "EIF2B5", "EIF4H", "EIF5B", "ELP2", "EMC3", "EPDR1", "EPHA7", "ERAP1", "ERAP2", "ERGIC1", 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0000000000000000000000000000000000000000..d19abdd454da0ff0291f507fac2f7596daff7d56 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Aggresome", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD6", 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"DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFL1", "EFNB1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELL", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERI1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM3C", "FAM49B", "FAM83D", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1L", "FNBP4", "FNDC3A", "FNTB", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA2", "GGT7", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNAQ", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM2", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HGH1", "HGS", "HIBCH", "HIC2", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK3", "HOXD11", "HOXD13", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "ICE2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS7", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA1522", "KIAA2013", "KIDINS220", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFC1", "KLC1", "KLC4", "KMT2A", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3HYPDH", "LACTB", "LAMP2", "LAMTOR1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLPH", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRP2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM14B", "LSM2", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN2A1", "MAN2B1", "MANBA", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP4", "MAP4K5", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBNL1", "MBOAT7", "MCAM", "MCC", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MECR", "MED1", "MED12", "MED13", "MED14", "MED17", "MED20", "MED23", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL15", "METTL16", "MFGE8", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICALL1", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIOS", "MIPEP", "MKI67", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPRIP", "MPST", "MRE11", "MRGBP", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL53", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MXRA7", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCDN", "NCEH1", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEO1", "NES", "NEU1", "NF1", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NME6", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOCT", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUS1", "NVL", "NXF1", "NXN", "OARD1", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGFR", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OSTF1", "OTUB1", "OTUD6B", "OTULIN", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PAM", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PATZ1", "PAXX", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK2", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF10", "PHF14", "PHF2", "PHF23", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLEKHA5", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMAIP1", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNISR", "PNKP", "PNMA1", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2B", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB11FIP1", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD18", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI1", "RAI14", "RALA", "RALGAPA1", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "REEP6", "REPS1", "RER1", "RETREG2", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RING1", "RINT1", "RIOK2", "RMDN1", "RMDN3", "RMND1", "RMND5A", "RNASEH2A", "RNF13", "RNF20", "RNF219", "RNF25", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUFY3", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SHTN1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A5", "SLC30A7", "SLC35B2", "SLC35F2", "SLC39A7", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD5", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX15", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPPL2A", "SPR", "SPRYD4", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRGAP2", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK11IP", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYNRG", "TAB1", "TACC3", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TES", "TEX10", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM106B", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM214", "TMEM230", "TMEM245", "TMEM63A", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWISTNB", "TXLNA", "TXLNG", "TXN2", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3C", "UBE4A", "UBL7", "UBLCP1", "UBP1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR41", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR74", "WDR77", "WDR82", "WIZ", "WNK1", "WRAP53", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM1", "ZMYM2", "ZMYM3", "ZMYM4", "ZMYND8", "ZNF148", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAMP", "ABCB1", "ACTN1", "ADAMTS1", "ADK", "AKT1", "AKT2", "ANXA1", "AP3S1", "APLP2", "APOB", "APP", "ARHGAP17", "ARPC5", "ARVCF", "ASCC2", "ATP1B3", "ATP2B4", "ATP6V0A1", "ATP6V0A2", "ATP7A", "ATP7B", "B4GALT1", "B4GALT3", "BAIAP2", "BICD2", "BROX", "BTRC", "C12orf73", "C1QBP", "C5orf15", "C9orf64", "CADM1", "CALCOCO1", "CAMK2G", "CANT1", "CD2AP", "CD47", "CDH2", "CHST12", "CHST14", "CLCN3", "CLCN6", "CLN6", "CMTR1", "COLEC12", "CREG1", "CTSA", "CTSB", "CTSC", "CUTA", "CXADR", "DBNL", "DNM3", "DSC3", "DSG2", "EFCAB14", "EHD1", "EHD4", "EIF5A", "EIF5B", "EPN1", "ERAP1", "ERAP2", "ETNK1", "EXOC6", "EXT2", "EZR", "F11R", "FAM114A2", "FAM192A", "FAM3C", "FAM83D", "FERMT2", "FLOT1", "FUCA1", "GAA", "GALNT2", "GALNT7", "GGT7", "GID8", "GLB1", "GLG1", "GM2A", "GOLIM4", "GOLM2", "GPHN", "GPR107", "GPR108", "GPR180", "GTF2F2", "GUSB", "HEXA", "HLA-A", "HSDL1", "IGF2R", "IMPAD1", "IQGAP2", "ITGAV", "ITGB1", "ITM2B", "KIAA0319L", "KIAA2013", "KIF1B", "LAMP2", "LAMTOR1", "LGMN", "LIPA", "LRP1", "LRP2", "MAN2A1", "MAN2B1", "MANBA", "MCAM", "MCUB", "METTL15", "MIA3", "MMACHC", "MTPN", "NAE1", "NAP1L1", "NBN", "NELFCD", "NEO1", "NEU1", "NIF3L1", "NME6", "NPC1", "NUCB1", "NUCB2", "NUDT9", "NUP35", "ODR4", "OTUD6B", "P4HA2", "PAFAH1B2", "PAIP1", "PAM", "PIP4K2C", "PLA2G15", "PLAA", "PNMA1", "PPFIA1", "PPHLN1", "PPP2R1B", "PPT1", "PPT2", "PRCP", "PSAP", "PTPRF", "QSOX2", "RAB23", "RFLNB", "RHOA", "RNF13", "SCAMP1", "SCARB1", "SCPEP1", "SDF4", "SEC16A", "SEPT7", "SFXN4", "SHTN1", "SLC19A1", "SLC30A5", "SLC35F2", "SLC3A2", "SLC6A15", "SORT1", "SPPL2A", "STARD3NL", "STK11IP", "STOM", "STX12", "STX3", "STX5", "STX6", "STX7", "SURF4", "TEDC1", "TFRC", "TGOLN2", "TIMM17B", "TJP2", "TM9SF3", "TMEM87A", "TOM1", "TRA2A", "TSPAN3", "UBE3C", "VANGL1", "VPS25", "YBX1", "ZADH2", "ZCCHC3", "ZNF148"]} \ No newline at end of file