Upload folder using huggingface_hub

interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:20f2903f83992fe3d3e3484066e1e1b753468b3191a154eaaa4294bbb41de5cc
+size 73676

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.508771929824561
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C285/C285_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7750155376009982	0.5829706099812677	0.5599130852980969	1.0	0.938677819470339	2	Q7LG56	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.4266169154228768	0.2396866746163855	0.8105731659827391	1.0	1.0	4	P21281,P38606,P06576	3

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ATP5B", "ATP6V1A", "ATP6V1B2", "RRM2B"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:c03dfe8ae3fb0e0beda22e98fd1efd71a853f04898d66518bcb7264f1e9f2748
+size 73533

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.5
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C285/C285_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4845505986377939	0.8785120198310312	0.3796659176730999	0.9999997687825704	0.9759747729112904	39	P43304,P04632,O75746,Q6NUK1,Q14257,O75340,Q9NWM8,P41208,P80303,Q02818,Q9UBV8,Q9BPX6,O95202,O95302,Q9Y680	15
+Peptidase M16, zinc-binding site [IPR001431]	0.5605327192275464	0.8261015107437425	0.4087465107665173	0.999999950253912	0.9759747729112904	5	P22695	1
+2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]	0.4162262977929859	0.1024860532651403	0.91837088243973	1.0	0.9759747729112904	3	O00330,P36957	2
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.3604723430702418	0.0301157084131263	0.9759747729112904	1.0	0.9759747729112904	2	O15270	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO19", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CAPNS1", "CETN2", "DLST", "FKBP14", "FKBP7", "FKBP9", "GPD2", "LETM1", "MICU1", "NUCB1", "NUCB2", "PDCD6", "PDHX", "PEF1", "RCN2", "SLC25A12", "SLC25A24", "SPTLC2", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Acyl-CoA dehydrogenase, conserved site [IPR006089]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:ade9ebdb606692a766816f51d6371ace95f586a8684721a2c67bd575df329cd7
+size 81506

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	4	8	2.4096134127185387	0.0159694318236072	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0003595516111798	0.0607401038440192	0.1169218221283287	0.0033170374819039	0.0002457979454447

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 273,
+    "title": "Average number of proteins per term",
+    "value": 2.58974358974359
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C285/C285_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,30 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8094956902381828	2.4096134127185387	0.0159694318236072	0.9876591526206678	0.4228946959866707	8	P56962,O43752,O60499,Q9P2W9	4
+Tetraspanin, conserved site [IPR018503]	0.8750388560770823	1.523842796186259	0.1275479860107267	1.0	0.6900272423660049	3	O60637,Q9H1Z9	2
+Thioredoxin, conserved site [IPR017937]	0.5460261683852246	1.3536762355446368	0.1758396930794212	1.0	0.7327719624277406	12	Q9H3N1,Q9H1E5	2
+Haem oxygenase conserved site [IPR018207]	0.9524549409571108	1.1920667534519118	0.2332350718895794	1.0	0.7360281676176113	2	P30519	1
+AMP-binding, conserved site [IPR020845]	0.5742018971774632	1.1447779132620508	0.2523011668270909	1.0	0.7360281676176113	7	Q9UKU0,P33121,O14975	3
+Intermediate filament protein, conserved site [IPR018039]	0.5511297424341083	1.1363083579105282	0.2558275340822726	1.0	0.7360281676176113	8	P08670,Q16352,P07196	3
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.5204547808315749	1.1355928132252748	0.2561270180354325	1.0	0.7360281676176113	11	Q06136,Q8NBN7,Q53GQ0	3
+Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]	0.89030453697949	0.9684861857867796	0.3328016148393993	1.0	0.8108341867162396	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]	0.89030453697949	0.9684861857867796	0.3328016148393993	1.0	0.8108341867162396	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]	0.89030453697949	0.9684861857867796	0.3328016148393993	1.0	0.8108341867162396	2	Q07820	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.721479639415608	0.9476175677419588	0.3433241794203612	1.0	0.8108341867162396	3	P09429,P26583	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.7125103291175612	0.9147105490722178	0.3603436048689501	1.0	0.8108341867162396	3	Q9H3P7	1
+Chromo domain, conserved site [IPR023779]	0.6948039950851397	0.8503103885261117	0.3951525423721276	1.0	0.8488071925294214	3	P83916	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.4602221710079121	0.6672613565615539	0.5046052054211141	1.0	0.9434061595752862	8	P49721,P28072	2
+Polyprenyl synthetase, conserved site [IPR033749]	0.8008079552516942	0.6642583502384684	0.506524973221715	1.0	0.9434061595752862	2	P14324	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.7886886264760531	0.6256120858338152	0.5315694095933097	1.0	0.9434061595752862	2	P14174	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.6147183198126143	0.5730420697870556	0.5666162094254374	1.0	0.9434061595752862	3	P50570	1
+14-3-3 protein, conserved site [IPR023409]	0.4634241740675292	0.538600337644501	0.5901626545395557	1.0	0.9434061595752862	6	P31946,P27348,P63104,P62258	4
+Mrp, conserved site [IPR000808]	0.756059664387823	0.5257088251420354	0.5990905311385071	1.0	0.9434061595752862	2	Q9Y5Y2	1
+UbiE/COQ5 methyltransferase, conserved site [IPR023576]	0.7489123679303964	0.5047249936316519	0.6137520038913884	1.0	0.9434061595752862	2	Q5HYK3	1
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.3618543870566297	0.1533639615848168	0.8781112631235155	1.0	1.0	6	Q9H845,P49748,P45954,P11310,Q92947	5
+Actin, conserved site [IPR004001]	0.5820385332504779	0.1414374144919762	0.8875243988504806	1.0	1.0	2	O96019	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.4258626049114129	0.1151143950594511	0.9083544501477968	1.0	1.0	3	P14625,P07900	2
+Histidine triad, conserved site [IPR019808]	0.5027967681790045	0.0657285662414003	0.9475939290122036	1.0	1.0	2	Q9BX68	1
+Fructose-bisphosphate aldolase class-I active site [IPR029768]	0.4894344313238178	0.0582146547033609	0.9535776477537314	1.0	1.0	2	P04075	1
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.4776258545680707	0.0525913659181301	0.9580574964509556	1.0	1.0	2	P06730	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.405531385954025	0.0337529458690689	0.9730741583016512	1.0	1.0	2	P24534	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.3396519577377416	0.0293982417268597	0.9765469750986966	1.0	1.0	2	O60568	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.3103233830845713	0.0266657499054591	0.9787263310284504	1.0	1.0	4	Q96SU4,P22059,Q9BZF1	3

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK1", "RIOK2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACAD9", "ACADM", "ACADSB", "ACADVL", "ACBD3", "ACSL1", "ACSL6", "ACTL6A", "ALDOA", "CBX1", "COQ5", "DNM2", "EEF1B2", "EIF4E", "FDPS", "GCDH", "HINT2", "HMGB1", "HMGB2", "HMOX2", "HSD17B12", "HSP90AA1", "HSP90B1", "INA", "KDSR", "MCL1", "MIF", "NEFL", "NUBP2", "OSBP", "OSBPL8", "OSBPL9", "PLOD3", "PSMB2", "PSMB6", "RDH13", "SLC27A2", "STX10", "STX17", "STX18", "STX6", "TMX1", "TMX4", "TSPAN10", "TSPAN3", "VIM", "YWHAB", "YWHAE", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Phospholipid/glycerol acyltransferase [IPR002123]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Phospholipid/glycerol acyltransferase [IPR002123]", "1": "EF-hand domain [IPR002048]", "2": "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "3": "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6d8cf504ca0dd065553b90a05f521ca2a77747c7dcff00fd027f03fe6976402b
+size 169425

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	6	2.3591367267694627	0.01831750543683	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.004020358667343	0.0014481500629001	0.0001725606130307	0.0025975272437437	0.018020673376298
+LEM domain [IPR003887]	3	6	2.1508010428330757	0.0314919067657419	2.237864077669903	5.759708737864078	0.8787481060627674	0.3228260833428172	1.2758866328838632	0.4653299410110203	1.033781091163317	0.2887768895441466	0.0109888575374462	1.0	0.0557540441617295	0.0081566962170519	7.614857799780336e-05
+Phospholipid/glycerol acyltransferase [IPR002123]	5	7	1.977422366896328	0.0479939077903295	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	0.0731095547591058	1.0	1.0	0.3236592382947187	6.703246650942136e-05

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 2549,
+    "title": "Average number of proteins per term",
+    "value": 2.1439780306002354
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C285/C285_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,183 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8642841648481028	2.3591367267694627	0.01831750543683	1.0	0.4844938791515771	6	O43169,O15173	2
+Reticulon [IPR003388]	0.9651741293532332	2.3260269820470967	0.0200171113038591	1.0	0.4844938791515771	4	O75298,Q16799,O95197	3
+LEM domain [IPR003887]	0.8158957629807612	2.1508010428330753	0.0314919067657419	1.0	0.4844938791515771	6	Q86XL3,P42167,P50402	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.7472649630641758	1.9774223668963276	0.0479939077903295	1.0	0.4844938791515771	7	O15228,Q8NF37,Q92604,O15120,Q9NUQ2	5
+Target SNARE coiled-coil homology domain [IPR000727]	0.6805629962390103	1.9355559265264035	0.0529221127404033	1.0	0.4870209899445079	10	P56962,O43752,O60499	3
+GOLD domain [IPR009038]	0.7529775054168742	1.872457004559112	0.0611434049050763	1.0	0.4870209899445079	6	Q9H3P7,Q9Y3A6,Q9Y3B3,P49755	4
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7897356143079153	1.8255432612706497	0.0679190890523022	1.0	0.4870209899445079	5	P05023,Q9HD20,P98194,P16615	4
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8029036896873404	1.6837499240144542	0.0922300085753624	1.0	0.5095764500647257	4	Q15629,Q96G23	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.708235709264626	1.6696512978241425	0.0949883747500537	1.0	0.5189449718891452	6	P55786,P09960,Q9UIQ6,Q9NZ08	4
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.708235709264626	1.6696512978241425	0.0949883747500537	1.0	0.5189449718891452	6	P55786,P09960,Q9UIQ6,Q9NZ08	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7894900497512412	1.629035002828113	0.1033056092609814	1.0	0.5304406209706813	4	P05023,P16615,P98194	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7894900497512412	1.629035002828113	0.1033056092609814	1.0	0.5304406209706813	4	P05023,P16615,P98194	3
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8958657133975695	1.6021181673767824	0.1091294813217211	1.0	0.5318758085833026	3	Q9Y282,Q96RQ1	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8958657133975695	1.6021181673767824	0.1091294813217211	1.0	0.5318758085833026	3	Q9Y282,Q96RQ1	2
+Tim10-like [IPR004217]	0.8930680758470476	1.5916176657575851	0.111470638261808	1.0	0.5380629836525301	3	P62072,Q9Y5J9	2
+Zinc finger, CHHC-type [IPR012996]	0.8542119987565997	1.4453703233467503	0.1483538945588722	1.0	0.5774599819132913	3	P55795,P31943	2
+Glycosyltransferase 2-like [IPR001173]	0.6578702289699422	1.4371503522303992	0.1506752765512453	1.0	0.5774599819132913	6	Q8N4A0	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.739427860696514	1.4232775401579751	0.1546557151897976	1.0	0.5787496905035708	4	P08670,Q16352,P07196	3
+N-acetylgalactosaminyltransferase [IPR045885]	0.7327973111326196	1.3958833922976408	0.1627496125718757	1.0	0.5863515084811461	4	Q8N4A0	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.8359816985404652	1.376584368656415	0.1686407864038526	1.0	0.5863515084811461	3	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.8359816985404652	1.376584368656415	0.1686407864038526	1.0	0.5863515084811461	3	P16435	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.8359816985404652	1.376584368656415	0.1686407864038526	1.0	0.5863515084811461	3	P16435	1
+ERAP1-like C-terminal domain [IPR024571]	0.7245024875621849	1.3615816351345642	0.1733299542435964	1.0	0.5938414695792034	4	P55786,Q9UIQ6,Q9NZ08	3
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8209147730112879	1.3197142268715292	0.186930448224988	1.0	0.6180100032756091	3	Q13505	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8209147730112879	1.3197142268715292	0.186930448224988	1.0	0.6180100032756091	3	Q13505	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.5376443617109988	1.233125072251873	0.2175291045750942	1.0	0.6444996228849778	11	P62942,Q9NWM8,Q14318,O95302	4
+FAD dependent oxidoreductase [IPR006076]	0.689259154421749	1.2156317617810235	0.2241252292496183	1.0	0.6462615490466934	4	Q9H9P8,Q96CU9	2
+Ricin B, lectin domain [IPR000772]	0.6438955801398654	1.1908185734267134	0.2337248158153064	1.0	0.6604928553361598	5	Q8N4A0	1
+SUN domain [IPR012919]	0.780505646027714	1.1674548407184773	0.2430267352914397	1.0	0.6690051135226053	3	Q9UH99	1
+Ovarian carcinoma immunoreactive antigen domain [IPR009764]	0.9440646364201356	1.1615411128421067	0.2454219139010796	1.0	0.670290054760165	2	Q9NX40	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.7771747989026805	1.1549429838178866	0.2481137757013598	1.0	0.670290054760165	3	P61289	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.7771747989026805	1.1549429838178866	0.2481137757013598	1.0	0.670290054760165	3	P61289	1
+AMP-dependent synthetase/ligase [IPR000873]	0.5742018971774632	1.1447779132620508	0.2523011668270909	1.0	0.6752549295607448	7	Q9UKU0,P33121,O14975	3
+Intermediate filament, rod domain [IPR039008]	0.5511297424341083	1.1363083579105282	0.2558275340822726	1.0	0.6792754003913677	8	P08670,Q16352,P07196	3
+Dynamin, GTPase domain [IPR001401]	0.6672605592482668	1.1245958921084214	0.2607603152492013	1.0	0.6816524252113252	4	P50570	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.7681069319241456	1.12092744065818	0.2623187493546599	1.0	0.6816524252113252	3	Q99797,P52888	2
+Choline/carnitine acyltransferase domain [IPR039551]	0.9325668116842764	1.1198529089723734	0.2627764483681334	1.0	0.6816524252113252	2	P23786	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.5334448134243225	1.0922200909338595	0.2747363737258605	1.0	0.68792044855326	9	O15254,Q15067	2
+Syntaxin 6, N-terminal [IPR015260]	0.9216904909881856	1.080592868270698	0.2798782563074069	1.0	0.6901968774159939	2	O60499	1
+Prenylcysteine lyase [IPR010795]	0.9207582349285272	1.0772364305567503	0.2813746537603734	1.0	0.6929700410001853	2	Q9UHG3	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6159631487298035	1.0677974218389747	0.2856119012976863	1.0	0.6969455694681498	5	Q9UKU0,P33121,O14975	3
+Acyltransferase, C-terminal domain [IPR032098]	0.8940335612181385	0.9816994825641204	0.3262479204076576	1.0	0.7346342306706	2	Q9NUQ2	1
+Potentiating neddylation domain [IPR005176]	0.7280562812106808	0.9718517863039918	0.3311242884416328	1.0	0.738483063246196	3	Q92564	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8899937849596034	0.9673865213207548	0.3333508455731535	1.0	0.738483063246196	2	Q9NVI7	1
+SUN coiled coil domain 2 [IPR040994]	0.8865755127408339	0.9553052456426028	0.3394233555318098	1.0	0.7426524748932044	2	Q9UH99	1
+EF-hand domain [IPR002048]	0.5105440952272072	0.9497582053589244	0.3422351269643884	1.0	0.7476899754454965	47	Q8NF37,P80303,O95302,Q9Y680,Q6NUK1,Q14257,Q8IYU8,P60660,P43304,P04632,O75746,P41208,Q02818,Q9UBV8,Q9BPX6,O75340,Q9NWM8,P14649,O95202	19
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.7125103291175612	0.9147105490722178	0.3603436048689501	1.0	0.7544699836895389	3	Q9H3P7	1
+1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]	0.8638906152890001	0.8758922534442228	0.3810886112154179	1.0	0.7736872183491225	2	O15120	1
+Armadillo repeat-containing domain [IPR006911]	0.8570540708514609	0.852248146187821	0.3940763794457367	1.0	0.7838473389156057	2	Q8N2F6	1
+Chromo domain subgroup [IPR017984]	0.6948039950851397	0.8503103885261117	0.3951525423721276	1.0	0.7838473389156057	3	P83916	1
+Chromo shadow domain [IPR008251]	0.6948039950851397	0.8503103885261117	0.3951525423721276	1.0	0.7838473389156057	3	P83916	1
+Thioredoxin domain [IPR013766]	0.4519604533594181	0.8473365105455443	0.3968075816453469	1.0	0.7853708515228959	26	Q9H3N1,Q96JJ7,Q9Y320,Q9H1E5	4
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8486637663144632	0.8234350281200885	0.4102606504893953	1.0	0.7976768864206474	2	Q8N2A8	1
+LEM-like domain [IPR013146]	0.8455562461155823	0.8128238628226366	0.4163190519382025	1.0	0.8033287383728072	2	P42167	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.4883228147113748	0.810834941830103	0.4174604654064335	1.0	0.804093868236525	8	P28161,Q9H7Z7	2
+EB1, C-terminal [IPR004953]	0.8399627097576144	0.793810068343656	0.4273060103655148	1.0	0.8126293219933781	2	Q15555	1
+Tim44-like domain [IPR007379]	0.8387197016780628	0.7896002730630848	0.4297612487365561	1.0	0.8131090566947905	2	Q9BRJ2	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8328154133001716	0.7696834224660476	0.4414877060446043	1.0	0.8242746585509539	2	O15254	1
+Patatin-like phospholipase domain [IPR002641]	0.6681847440970501	0.7552221182328099	0.4501157195541123	1.0	0.829071644989028	3	Q96AD5	1
+Dynamin, N-terminal [IPR045063]	0.4688815233077528	0.7112269438615054	0.4769436145492354	1.0	0.8477888936443522	8	P50570,Q8IWA4	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.4688815233077528	0.7112269438615054	0.4769436145492354	1.0	0.8477888936443522	8	P50570,Q8IWA4	2
+DDHD domain [IPR004177]	0.8147917961466771	0.7097561284134031	0.477855379059066	1.0	0.8488176733251285	2	O94830	1
+GYF domain [IPR003169]	0.8091982597886782	0.6914461729628857	0.4892851961415174	1.0	0.8602156455028097	2	O95400	1
+Major sperm protein (MSP) domain [IPR000535]	0.6369288156667725	0.6470251699275295	0.5176156535651386	1.0	0.8761452932046314	3	O95292,Q9P0L0	2
+Peptidase M16, N-terminal [IPR011765]	0.4630388114877765	0.6030939829392431	0.546446169050598	1.0	0.8892352046680174	7	P22695	1
+Peptidase M16, C-terminal [IPR007863]	0.4630388114877765	0.6030939829392431	0.546446169050598	1.0	0.8892352046680174	7	P22695	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7787445618396409	0.5944941925403695	0.5521816254091954	1.0	0.8920062593006965	2	P13674	1
+FAD-binding domain, PCMH-type [IPR016166]	0.7784338098197675	0.5935307922784439	0.5528259819243138	1.0	0.8920062593006965	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.7784338098197675	0.5935307922784439	0.5528259819243138	1.0	0.8920062593006965	2	Q15392	1
+U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]	0.7771908017401925	0.5896828044045999	0.5554033257042237	1.0	0.8920062593006965	2	P09661	1
+Dynamin GTPase effector [IPR003130]	0.6147183198126143	0.5730420697870556	0.5666162094254374	1.0	0.8976412167964203	3	P50570	1
+GTPase effector domain [IPR020850]	0.6147183198126143	0.5730420697870556	0.5666162094254374	1.0	0.8976412167964203	3	P50570	1
+Dynamin stalk domain [IPR000375]	0.6147183198126143	0.5730420697870556	0.5666162094254374	1.0	0.8976412167964203	3	P50570	1
+14-3-3 domain [IPR023410]	0.4634241740675292	0.538600337644501	0.5901626545395557	1.0	0.9067658869326868	6	P31946,P27348,P63104,P62258	4
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.7495338719701468	0.5065358214628721	0.6124805492942	1.0	0.9165629310152716	2	P54725	1
+XPC-binding domain [IPR015360]	0.7495338719701468	0.5065358214628721	0.6124805492942	1.0	0.9165629310152716	2	P54725	1
+Tudor domain [IPR002999]	0.4276136600328912	0.5050653143911865	0.6135129622738429	1.0	0.9165629310152716	8	Q9Y2W6	1
+NOPS [IPR012975]	0.593410009325457	0.5048454433359757	0.6136673952113056	1.0	0.9165629310152716	3	P23246,Q8WXF1	2
+Heat shock chaperonin-binding [IPR006636]	0.4803165795791674	0.4947515087827757	0.6207755373588988	1.0	0.9167768509431246	5	Q9UHD9,P54725	2
+BAR domain [IPR004148]	0.5042950474085242	0.4839206096945087	0.6284422131418739	1.0	0.9221731950727138	4	Q9Y371	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.4358487808969706	0.4776589572357995	0.6328929608425671	1.0	0.9223808788951992	7	Q03518,P33897	2
+p21 activated kinase binding domain [IPR033923]	0.7302672467370803	0.4516869502502125	0.6514945206311888	1.0	0.9324309562542956	2	Q13153	1
+CRIB domain [IPR000095]	0.7302672467370803	0.4516869502502125	0.6514945206311888	1.0	0.9324309562542956	2	Q13153	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7215661901802423	0.4278309513721032	0.6687742009648279	1.0	0.936508354538831	2	O60506	1
+CRA domain [IPR013144]	0.7197016780609135	0.4227967242224942	0.6724435778840181	1.0	0.9368817467825618	2	Q9NWU2	1
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.7197016780609135	0.4227967242224942	0.6724435778840181	1.0	0.9368817467825618	2	Q9NWU2	1
+CRK, C-terminal SH3 domain [IPR035458]	0.7091361093847174	0.3948052653259342	0.6929866087810628	1.0	0.9387263235521226	2	P46109	1
+CRK, N-terminal SH3 domain [IPR035457]	0.7091361093847174	0.3948052653259342	0.6929866087810628	1.0	0.9387263235521226	2	P46109	1
+BSD domain [IPR005607]	0.7041640770665076	0.3819562508896966	0.7024938154728306	1.0	0.9397395207865684	2	Q9NW68	1
+CARG-binding factor, N-terminal [IPR012956]	0.698881292728408	0.3685377561230011	0.7124722977910922	1.0	0.946374094356172	2	Q14103	1
+OCRE domain [IPR041591]	0.6942200124300812	0.3569018004476948	0.721165321754146	1.0	0.9511461071711104	2	P78332	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.5424662352366949	0.3556584389994657	0.7220963733220032	1.0	0.9517185396058871	3	P13674	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.6908017402113186	0.3484923543768025	0.7274704547276702	1.0	0.9534232127619484	2	Q96CX2	1
+F-BAR domain [IPR031160]	0.6814791796146752	0.3261003800695873	0.7443484094781618	1.0	0.9576024660676266	2	Q9UKS6	1
+FCH domain [IPR001060]	0.6814791796146752	0.3261003800695873	0.7443484094781618	1.0	0.9576024660676266	2	Q9UKS6	1
+Band 7 domain [IPR001107]	0.3890732696729123	0.3240799294540419	0.7458775215999713	1.0	0.9576024660676266	8	Q9UJZ1,Q99623	2
+Extended synaptotagmin, C2A domain [IPR037733]	0.6796146674953425	0.3217189378145956	0.7476656297011206	1.0	0.9576024660676266	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6796146674953425	0.3217189378145956	0.7476656297011206	1.0	0.9576024660676266	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.6796146674953425	0.3217189378145956	0.7476656297011206	1.0	0.9576024660676266	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6796146674953425	0.3217189378145956	0.7476656297011206	1.0	0.9576024660676266	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6796146674953425	0.3217189378145956	0.7476656297011206	1.0	0.9576024660676266	2	A0FGR8	1
+Proteasomal ATPase OB C-terminal domain [IPR032501]	0.4245723172628256	0.2928152552839853	0.7696633670613333	1.0	0.9604998681995212	5	P62195,P62191,P62333,P17980	4
+v-SNARE, coiled-coil homology domain [IPR042855]	0.5129397016747558	0.280123526264341	0.7793827356230703	1.0	0.9604998681995212	3	O75396	1
+Longin domain [IPR010908]	0.5129397016747558	0.280123526264341	0.7793827356230703	1.0	0.9604998681995212	3	O75396	1
+Immunoglobulin-like domain [IPR007110]	0.3505692494553509	0.2801099836850549	0.7793931253205924	1.0	0.9604998681995212	13	P10586,Q08722,Q9Y639,P35613	4
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.657551274083278	0.27241166560784	0.7853055039057779	1.0	0.9604998681995212	2	O75608	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.3551540853307742	0.267933824797688	0.7887502568410056	1.0	0.9612847978044072	12	P28161,Q9H7Z7,Q9Y696	3
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.5026422132421552	0.2559532786897883	0.7979869140069953	1.0	0.9648072963953378	3	O43823,Q5BKZ1	2
+Exosome complex component, N-terminal domain [IPR025721]	0.6435674331883249	0.2436670501082473	0.8074886944749409	1.0	0.9651269968103928	2	Q9Y3B2	1
+SCP2 sterol-binding domain [IPR003033]	0.4958035436742403	0.2405584909910234	0.8098973248671437	1.0	0.9651269968103928	3	P51659,P22307	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.4266169154228768	0.2396866746163855	0.8105731659827391	1.0	0.9651269968103928	4	P21281,P38606,P06576	3
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.4266169154228768	0.2396866746163855	0.8105731659827391	1.0	0.9651269968103928	4	P21281,P38606,P06576	3
+60S ribosomal protein L10P, insertion domain [IPR040637]	0.6407706650093319	0.2381581137474256	0.8117584628742536	1.0	0.9651269968103928	2	Q9UKD2	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.4259950248756159	0.238017257203381	0.8118677094759701	1.0	0.9651269968103928	4	P14625,P07900,Q12931	3
+Far upstream element-binding protein, C-terminal [IPR015096]	0.6389061528900032	0.2345304081064233	0.814573229117461	1.0	0.9651269968103928	2	Q92945	1
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.6379738968303387	0.2327300684606076	0.815971018973267	1.0	0.9651269968103928	2	Q16576	1
+Death domain [IPR000488]	0.4920733602735566	0.2323870233996901	0.8162374269059467	1.0	0.9651269968103928	3	Q12955,Q13546	2
+FCP1 homology domain [IPR004274]	0.489897419956491	0.2276947592650569	0.8198835469353365	1.0	0.9663652901417976	3	Q8WVY7,Q3ZCQ8	2
+Signal recognition particle SRP54, helical bundle [IPR013822]	0.6286513362336953	0.2152248038503316	0.8295920533661096	1.0	0.9691247222869906	2	P61011	1
+Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]	0.6286513362336953	0.2152248038503316	0.8295920533661096	1.0	0.9691247222869906	2	P61011	1
+Chromo domain [IPR023780]	0.4142675135582225	0.2075278349093306	0.8355976566994485	1.0	0.9717911220046376	4	P83916	1
+Man1/Src1, C-terminal [IPR018996]	0.6236793039154854	0.2062610917243753	0.836586969328883	1.0	0.9717911220046376	2	Q8NC56	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.619328775637031	0.198631530447891	0.8425509873034287	1.0	0.9741368697188002	2	Q14011	1
+Peptidase M41 [IPR000642]	0.6087632069608495	0.1809357445685445	0.8564180117626603	1.0	0.9761102527823156	2	Q96TA2	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.3619670090258257	0.1748722965280682	0.8611799789881587	1.0	0.9761102527823156	7	Q9H845,Q709F0,P49748,P45954,P11310,Q92947	6
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.3619670090258257	0.1748722965280682	0.8611799789881587	1.0	0.9761102527823156	7	Q9H845,Q709F0,P49748,P45954,P11310,Q92947	6
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.3809192463950331	0.1616670663804847	0.8715680405384663	1.0	0.9761102527823156	5	P13674	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.3809192463950331	0.1616670663804847	0.8715680405384663	1.0	0.9761102527823156	5	P13674	1
+EXPERA domain [IPR033118]	0.5913610938471128	0.1543635501520394	0.8773230919113597	1.0	0.9761934506758128	2	Q5BJF2	1
+UBX domain [IPR001012]	0.3611011242071351	0.1510524609546334	0.8799343327661378	1.0	0.9768957379010824	6	O94888,Q92575,Q9UNZ2	3
+NAD-dependent epimerase/dehydratase [IPR001509]	0.5711622125543938	0.1274940083869143	0.8985494150996398	1.0	0.9851113371521532	2	Q9NRG7	1
+Thioesterase domain [IPR006683]	0.5553138595400923	0.1093175198289949	0.9129506510584896	1.0	0.9902837960120072	2	O00154	1
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.5494095711622171	0.1031770117751726	0.917822484470703	1.0	0.9902837960120072	2	Q13526	1
+2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]	0.4162262977929859	0.1024860532651403	0.91837088243973	1.0	0.9902837960120072	3	O00330,P36957	2
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.5453697949036778	0.0991676901125093	0.9210051279291496	1.0	0.9913070458746333	2	Q99707	1
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.539154754505915	0.0932982554752312	0.9256666179685612	1.0	0.9913070458746333	2	P32322	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.539154754505915	0.0932982554752312	0.9256666179685612	1.0	0.9913070458746333	2	P32322	1
+Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]	0.536668738346813	0.0910501721768217	0.9274527249514904	1.0	0.9913070458746333	2	P38117	1
+Rhodanese-like domain [IPR001763]	0.3468118195956389	0.0803066551040916	0.9359933653042176	1.0	0.9913070458746333	5	P25325,Q16762,P40818,Q99956	4
+tRNA-binding domain [IPR002547]	0.5205096333126309	0.0777758753483227	0.9380063369891716	1.0	0.9914764611360084	2	P54577	1
+ENTH  domain [IPR013809]	0.3863848305875072	0.070199085500307	0.9440352021965666	1.0	0.9946365988595872	3	Q14677,Q9Y6I3	2
+Nuclear transport factor 2 domain [IPR002075]	0.3442164179104429	0.0677701608634469	0.945968597316037	1.0	0.9950955279083448	4	Q9UN86,P61970,Q9UBU9	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.3442164179104429	0.0677701608634469	0.945968597316037	1.0	0.9950955279083448	4	Q9UN86,P61970,Q9UBU9	3
+Peptidase M20, dimerisation domain [IPR011650]	0.5037290242386719	0.0663014341143155	0.947137841481012	1.0	0.9950955279083448	2	Q96KP4	1
+CDC48, N-terminal subdomain [IPR003338]	0.4965817277812444	0.0620743305549708	0.95050363881619	1.0	0.9970509363549253	2	P46459	1
+CDC48, domain 2 [IPR004201]	0.4965817277812444	0.0620743305549708	0.95050363881619	1.0	0.9970509363549253	2	P46459	1
+CAP Gly-rich domain [IPR000938]	0.3627603357165093	0.0513901540983798	0.9590146302990552	1.0	0.9995846958307736	3	Q14203,Q99426	2
+Cyclin, N-terminal [IPR006671]	0.3596518495492722	0.0493173702609114	0.9606663768947636	1.0	0.9995846958307736	3	O95067,P20248	2
+Cyclin, C-terminal domain [IPR004367]	0.3596518495492722	0.0493173702609114	0.9606663768947636	1.0	0.9995846958307736	3	O95067,P20248	2
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.4683032939714237	0.0487652647091231	0.9611063639709952	1.0	0.9995846958307736	2	O94979	1
+Arf GTPase activating protein [IPR001164]	0.4639527656929901	0.0471513077757622	0.96239263508961	1.0	0.999831266829325	2	Q8N6T3	1
+Exportin-2, central domain [IPR013713]	0.3509480882810165	0.0439727483576339	0.9649261265089382	1.0	0.999831266829325	3	O15397,P55060	2
+Rab-GTPase-TBC domain [IPR000195]	0.3246268656716358	0.0420122192938992	0.9664889571303684	1.0	0.999831266829325	4	Q8TC07,Q9Y3P9,Q66K14	3
+Survival motor neuron [IPR010304]	0.4350528278433967	0.0388374911342448	0.9690199537685384	1.0	0.999831266829325	2	Q16637	1
+CTP synthase GATase domain [IPR033828]	0.4244872591672028	0.0366855516615527	0.9707357289927444	1.0	0.999831266829325	2	Q9NRF8	1
+CTP synthase, N-terminal [IPR017456]	0.4244872591672028	0.0366855516615527	0.9707357289927444	1.0	0.999831266829325	2	Q9NRF8	1
+Adenylate kinase, active site lid domain [IPR007862]	0.4192044748290964	0.0357571004947958	0.9714760400199812	1.0	0.999831266829325	2	P54819	1
+Peripheral subunit-binding domain [IPR004167]	0.4160969546302154	0.035253094729659	0.9718779250439072	1.0	0.999831266829325	2	O00330	1
+ELMO domain [IPR006816]	0.4108141702921165	0.0344634516483755	0.972507586383928	1.0	0.999831266829325	2	Q8IZ81	1
+CBS domain [IPR000644]	0.3219284603421389	0.0337645191615184	0.973064929410649	1.0	0.999831266829325	5	Q8NE01,P54619,P51790,P12268	4
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.405531385954025	0.0337529458690689	0.9730741583016512	1.0	0.999831266829325	2	P24534	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.405531385954025	0.0337529458690689	0.9730741583016512	1.0	0.999831266829325	2	P24534	1
+Acyl transferase [IPR014043]	0.3943443132380548	0.0324823835423349	0.974087364513186	1.0	0.999831266829325	2	Q8IVS2	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.388750776880062	0.031953095423237	0.9745094562079044	1.0	0.999831266829325	2	Q15120	1
+Histidine kinase domain [IPR005467]	0.388750776880062	0.031953095423237	0.9745094562079044	1.0	0.999831266829325	2	Q15120	1
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.3452454940957223	0.0295525881415113	0.9764238779625702	1.0	0.999831266829325	2	P49591	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.3396519577377416	0.0293982417268597	0.9765469750986966	1.0	0.999831266829325	2	O60568	1
+ZU5 domain [IPR000906]	0.3349906774394144	0.029287307898361	0.9766354493913678	1.0	0.999831266829325	2	Q12955	1
+Ribosomal protein L11, N-terminal [IPR020784]	0.3225605966438896	0.0290571151143951	0.9768190385238537	1.0	0.999831266829325	2	Q9Y3B7	1
+Ribosomal protein L11, C-terminal [IPR020783]	0.3225605966438896	0.0290571151143951	0.9768190385238537	1.0	0.999831266829325	2	Q9Y3B7	1
+rRNA-processing arch domain [IPR025696]	0.3157240522063524	0.0289637932360981	0.976893467283252	1.0	0.999831266829325	2	Q15477	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.3157240522063524	0.0289637932360981	0.976893467283252	1.0	0.999831266829325	2	Q15477	1
+RuvB-like, AAA-lid domain [IPR041048]	0.3073337476693719	0.0288744660917611	0.9769647102355136	1.0	0.999831266829325	2	Q9Y230	1
+TIP49, P-loop domain [IPR010339]	0.3073337476693719	0.0288744660917611	0.9769647102355136	1.0	0.999831266829325	2	Q9Y230	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]	0.299875699192057	0.0288139251610978	0.9770129948191126	1.0	0.999831266829325	2	Q13423	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]	0.299875699192057	0.0288139251610978	0.9770129948191126	1.0	0.999831266829325	2	Q13423	1
+3'-5' exonuclease domain [IPR002562]	0.2840273461777634	0.0287285514431922	0.9770810850026868	1.0	0.999831266829325	2	Q9NVH0	1
+Domain of unknown function DUF4217 [IPR025313]	0.3089835250233159	0.0263757889100655	0.9789576050813544	1.0	1.0	3	Q13206,Q8NHQ9	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.3094539433016173	0.0258224294599698	0.9793989716905174	1.0	1.0	4	Q9Y5X3	1
+GRAM domain [IPR004182]	0.2918868511035163	0.0222743815379461	0.9822290843825132	1.0	1.0	3	Q13614,Q66K14	2
+Ribosomal protein S10 domain [IPR027486]	0.2912651538700717	0.0221510344921705	0.9823274768092732	1.0	1.0	3	P60866,P82664	2
+Ran binding domain [IPR000156]	0.2814054726368079	0.0036593673340899	0.9970802538181966	1.0	1.0	4	Q9UKX7,P43487,Q9H6Z4	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Glutathione Transferase family [IPR040079]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Glutathione Transferase family [IPR040079]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "3": "Small GTPase [IPR001806]", "4": "26S proteasome regulatory subunit P45-like [IPR005937]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:620356ae30bc52b6a18e35be87c5751ae6e78ba4e4117aaf490592dc9121b6c7
+size 226397

interpro_family/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Mitochondrial carrier protein [IPR002067]	12	13	2.6580728129196625	0.0078588911811079	5.686893203883495	11.07766990291262	0.8032246115450145	0.31892620527414	3.2338505495684404	1.5403272908315857	1.3918146051602212	0.3274613788058813	0.0020854405553751	1.0	0.1741653971767485	0.0011814468070448	1.4497628230363953e-07
+Syntaxin [IPR045242]	3	8	2.1863728899488084	0.0287883353494142	2.674757281553398	5.815533980582524	0.7134969984167514	0.3462495636510407	1.4434464182805606	1.4295601388514203	1.142372356309129	0.3001529293380739	0.0063803247206459	1.0	1.0	0.0435926191526008	0.003721367796782
+Glutathione Transferase family [IPR040079]	5	11	2.122602537136364	0.0337871721823204	2.6650485436893203	9.45388349514563	0.453215617797485	0.4615521029697171	1.6850115229858122	1.256172900264393	0.947748980990547	0.2879961408071128	0.0575030175044007	0.0652597674910206	0.1253337423142017	0.0435926191526008	0.0003671727016274