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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a345316b20eca1098a5952e62c64be1f922ba0a6eeb5c2dcec478a06ea6d12de
+size 72389

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.508771929824561
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C287/C287_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.8644700031084728	1.5987681260254316	0.1098721338040635	0.998685421150866	0.4953481305480799	3	Q9H3G5,Q9HB40	2
+Histidine acid phosphatase active site [IPR033379]	0.8937228091982499	1.2792007680872244	0.2008263654618569	0.9999971780753182	0.4977001231011237	2	Q9NPH0	1
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.5774253731343223	0.8225876647422834	0.410742515695548	0.9999999999999192	0.668923525561321	4	P06576,P38606,P25705	3
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.4906774394033667	0.1133473269286817	0.9097551975096104	1.0	0.9655751211114736	2	Q7LG56	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "ATP5A1", "ATP5B", "ATP6V1A", "CPVL", "RRM2B", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:788636e2313b331342e72e3eb961477b700b8b80db4799ad80fa398d40b1d8d2
+size 72705

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	6	7	2.739386835901925	0.0061553901166635	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.5282118980338711e-09	1.0	9.745982190989103e-07	1.5111885198827808e-10	2.0456909676363405e-08

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.5
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C287/C287_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9582944288826618	2.739386835901925	0.0061553901166635	0.1792865074607858	0.1694079689528998	7	P07437,P04350,Q9BVA1,P68371,Q13885,Q9BUF5	6
+Peptidase M16, zinc-binding site [IPR001431]	0.452106832742543	0.4023518691928555	0.6874250865278322	1.0	0.9903324690271216	5	Q10713	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.4810441267868332	0.1044183738969015	0.916837342124846	1.0	0.9903324690271216	2	O15270	1
+Aconitase family, 4Fe-4S cluster binding site [IPR018136]	0.3244251087632197	0.0509258845609479	0.959384579370024	1.0	0.9903324690271216	2	P21399	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO19", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["ACO1", "PMPCA", "SPTLC2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "Thioredoxin, conserved site [IPR017937]", "2": "Guanylate kinase, conserved site [IPR020590]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:a0cfaef94c9f0d586c7bb726cd2eec4099d18548971d56346c23cd1739b49b65
+size 75014

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	6	8	2.691726682894356	0.0071083173052972	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.039468633309204e-06	1.0	2.214575962840231e-05	1.1087547419726414e-07	1.2309793424334824e-05
+Syntaxin/epimorphin, conserved site [IPR006012]	2	8	2.407050220278732	0.0160819582054632	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.0083289148048966	0.0017760204843955	0.0002296483500821	0.0033170374819039	0.0227185425065092

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 273,
+    "title": "Average number of proteins per term",
+    "value": 2.58974358974359
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C287/C287_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,32 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9482420995001823	2.691726682894356	0.0071083173052972	0.8573698809777666	0.8781822362880195	8	P07437,P04350,Q9BVA1,P68371,Q13885,Q9BUF5	6
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8802959516597795	2.4070502202787316	0.0160819582054632	0.9880384820357548	0.8781822362880195	8	O43752,O60499	2
+Tetraspanin, conserved site [IPR018503]	0.9695368355610792	2.0007163788860596	0.0454229633158038	0.9999969210807828	0.8781822362880195	3	O43657,O60637	2
+Haem oxygenase conserved site [IPR018207]	0.9633312616531962	1.5532312195450084	0.1203679053837907	0.9999999999999992	0.8781822362880195	2	P30519	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.7298734686764439	1.0767673178141477	0.2815842295124766	1.0	0.9208062850482062	3	Q9H3P7	1
+Sterol reductase, conserved site [IPR018083]	0.8412057178371641	1.0751706324876862	0.2822983410282866	1.0	0.9208062850482062	2	Q14739	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.8203853325046633	0.9956486772817223	0.3194208747459326	1.0	0.9208062850482062	2	P04066	1
+AMP-binding, conserved site [IPR020845]	0.5678497053667645	0.9907842835305576	0.32179092518936	1.0	0.9208062850482062	7	Q9UKU0,P33121	2
+Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]	0.8126165320074603	0.9662506719691812	0.333918762709789	1.0	0.9208062850482062	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]	0.8126165320074603	0.9662506719691812	0.333918762709789	1.0	0.9208062850482062	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]	0.8126165320074603	0.9662506719691812	0.333918762709789	1.0	0.9208062850482062	2	Q07820	1
+Methylthiotransferase, conserved site [IPR020612]	0.8051584835301239	0.9381885717782042	0.3481475103582516	1.0	0.9310891126250664	2	Q5VV42	1
+Thioredoxin, conserved site [IPR017937]	0.557708103723653	0.8789955550305976	0.3794036859244809	1.0	0.9680112734334888	12	Q9H3N1,O95881,Q9H1E5,Q96JJ7,Q99757,O43396	6
+Mrp, conserved site [IPR000808]	0.7607209446861448	0.774978182715691	0.4383525515887065	1.0	1.0	2	Q9Y5Y2	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.7591671845867043	0.7694176762789295	0.4416453984432782	1.0	1.0	2	P11279	1
+UbiE/COQ5 methyltransferase, conserved site [IPR023576]	0.7520198881292776	0.7439874394758889	0.4568840740103601	1.0	1.0	2	O43159	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.4979506391454942	0.6627321465197398	0.5075021175060743	1.0	1.0	7	P51648,P51649	2
+Guanylate kinase, conserved site [IPR020590]	0.4713752333540737	0.5566789027246202	0.5777468338251883	1.0	1.0	6	Q8N3R9,Q9NZW5,Q00013,Q14168,O14936	5
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.5840845508237547	0.5469831210695234	0.5843903282928524	1.0	1.0	3	P26583,O15347	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.4515657826585705	0.4414734488669556	0.6588702791019896	1.0	1.0	8	P49721,P20618	2
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.5359030152315909	0.3976714550621369	0.6908723813405464	1.0	1.0	3	Q9BXS5,Q96CW1	2
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.6013051584835406	0.292528651258954	0.7698824568779941	1.0	1.0	2	P15880	1
+Ribosomal protein L30, conserved site [IPR018038]	0.5571783716594279	0.2034757045001169	0.8387632334707011	1.0	1.0	2	P18124	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.5540708514605451	0.1980909196612199	0.8429739291261478	1.0	1.0	2	P10644	1
+Histidine triad, conserved site [IPR019808]	0.5478558110627851	0.1876744031920946	0.8511318969965787	1.0	1.0	2	Q9BX68	1
+S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]	0.5444375388440158	0.1821456742526255	0.8554684053480348	1.0	1.0	2	O43865	1
+Serpin, conserved site [IPR023795]	0.5229956494717347	0.1506790402203417	0.8802289079201002	1.0	1.0	2	P50454	1
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.4934742075823647	0.1161212464549376	0.9075564504843068	1.0	1.0	2	P06730	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.4425108763207094	0.0775320277699816	0.9382003134717642	1.0	1.0	2	P40939	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.3442353058967368	0.016276782564348	0.9870135799181734	1.0	1.0	11	Q06136,Q8NBN7,Q6IAN0,Q53GQ0	4
+ABC transporter-like, conserved site [IPR017871]	0.3349543655834615	0.0029998458446912	0.9976064729056544	1.0	1.0	10	Q03518,P08183,P33897,O75027	4

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK1", "RIOK2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ACBD3", "ACSL1", "ACSL6", "AHCYL1", "ALDH3A2", "ALDH5A1", "AP1M1", "AP2M1", "CASK", "CDKAL1", "DHRS7B", "EIF4E", "FUCA1", "HADHA", "HINT2", "HMGB2", "HMGB3", "HMOX2", "HSD17B12", "KDSR", "LAMP1", "LBR", "MCL1", "MPP1", "MPP2", "MPP5", "MPP6", "NUBP2", "PRKAR1A", "PSMB1", "PSMB2", "RDH13", "RPL7", "RPS2", "RRP8", "SERPINH1", "STX10", "STX6", "TAP1", "TMX1", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXN2", "TXNDC12", "TXNL1"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "GOLD domain [IPR009038]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "GOLD domain [IPR009038]", "3": "CID domain [IPR006569]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:47f5fc58f3f2441378225e61a684c4345b19a1c8da81bb5db89fbd87d677dd39
+size 101494

interpro_domain/df_merge.tsv

@@ -0,0 +1,5 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin/FtsZ, GTPase domain [IPR003008]	6	8	2.691726682894356	0.0071083173052972	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.039468633309204e-06	1.0	2.214575962840231e-05	1.1087547419726414e-07	1.2309793424334824e-05
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	6	8	2.691726682894356	0.0071083173052972	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	6.539704218574156e-07	1.0	1.7352123755419733e-05	6.917341646628312e-08	7.850220860580527e-06
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	2.307725813296474	0.0210143914144682	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0006778239834459	1.0	1.0	0.0152248647419399	0.0035298468720628
+GOLD domain [IPR009038]	5	6	2.144521516612313	0.0319911232862673	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0685743771901276	0.0619434524836269	0.0066572828402184	0.0379575415698398	0.0002481332774246

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 2549,
+    "title": "Average number of proteins per term",
+    "value": 2.1439780306002354
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C287/C287_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,195 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.9482420995001823	2.691726682894356	0.0071083173052972	0.9999999873271735	0.8402162579375394	8	P07437,P04350,Q9BVA1,P68371,Q13885,Q9BUF5	6
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.9482420995001823	2.691726682894356	0.0071083173052972	0.9999999873271735	0.8402162579375394	8	P07437,P04350,Q9BVA1,P68371,Q13885,Q9BUF5	6
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.894867807153961	2.307725813296474	0.0210143914144682	1.0	0.8402162579375394	5	Q9HD20,P16615,P20020,P98194	4
+Reticulon [IPR003388]	0.9200870646766156	2.2410543562927883	0.0250225542806901	1.0	0.8402162579375394	4	O95197,Q9NQC3,O75298	3
+GOLD domain [IPR009038]	0.8154947106409559	2.144521516612313	0.0319911232862673	1.0	0.8402162579375394	6	Q9H3P7,Q9BVK6,Q15363,P49755,Q9Y3B3	5
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8945895522388053	2.1398844150038467	0.0323641089135948	1.0	0.8402162579375394	4	P16615,P20020,P98194	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8945895522388053	2.1398844150038467	0.0323641089135948	1.0	0.8402162579375394	4	P16615,P20020,P98194	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7729418778892603	1.9565932727027044	0.050395306583447	1.0	0.8402162579375394	6	O00264,O15173,O43169	3
+N-acetylgalactosaminyltransferase [IPR045885]	0.8354751597176591	1.9012806248796368	0.0572652654812206	1.0	0.8402162579375394	4	Q8N4A0	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.83511540651433	1.8998118869124057	0.057457810431049	1.0	0.8402162579375394	4	Q15629,Q96G23	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7919043195436375	1.8758636375598432	0.0606740068685744	1.0	0.8402162579375394	5	Q8WWV3	1
+LEM domain [IPR003887]	0.7382034851520299	1.800280715020118	0.0718163244324177	1.0	0.8402162579375394	6	P50402,P42167,Q86XL3	3
+Target SNARE coiled-coil homology domain [IPR000727]	0.742506338509027	1.7792533213637411	0.0751982400320432	1.0	0.8402162579375394	10	O60499	1
+Glycosyltransferase 2-like [IPR001173]	0.7318131687381748	1.7712516601952937	0.076518862048599	1.0	0.8402162579375394	6	Q8N4A0	1
+Ricin B, lectin domain [IPR000772]	0.7569928108127141	1.7250432739121653	0.0845196741923124	1.0	0.8402162579375394	5	Q8N4A0	1
+Syntaxin 6, N-terminal [IPR015260]	0.9872591671845856	1.647574430280112	0.0994400310600029	1.0	0.8402162579375394	2	O60499	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9810441267868242	1.6230805744690606	0.1045721816111142	1.0	0.8402162579375394	2	Q8IV08	1
+Tim10-like [IPR004217]	0.8576313335405662	1.5722901061225376	0.1158832865277477	1.0	0.8402162579375394	3	P62072,Q9Y5J6	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.679841794837966	1.532209456687195	0.1254707556693697	1.0	0.8402162579375394	6	Q9NZ08,P55786	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.679841794837966	1.532209456687195	0.1254707556693697	1.0	0.8402162579375394	6	Q9NZ08,P55786	2
+Potentiating neddylation domain [IPR005176]	0.8449585250015323	1.5231563300207018	0.1277195987036625	1.0	0.8402162579375394	3	Q92564	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9527656929770048	1.5115543152141853	0.1306472811539913	1.0	0.8402162579375394	2	O00116	1
+FAD linked oxidase, N-terminal [IPR006094]	0.9527656929770048	1.5115543152141853	0.1306472811539913	1.0	0.8402162579375394	2	O00116	1
+EXPERA domain [IPR033118]	0.9474829086389064	1.4907174391638611	0.1360356955401456	1.0	0.8402162579375394	2	Q5BJF2	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8358719303698928	1.487881523899451	0.1367821410284773	1.0	0.8402162579375394	3	Q9Y282,Q96RQ1	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8358719303698928	1.487881523899451	0.1367821410284773	1.0	0.8402162579375394	3	Q9Y282,Q96RQ1	2
+Dynamin, GTPase domain [IPR001401]	0.7354048592191342	1.4860694932185323	0.1372607405377108	1.0	0.8402162579375394	4	O60313	1
+CBS domain [IPR000644]	0.6975306332259986	1.4637949765502272	0.1432499754233478	1.0	0.8402162579375394	5	P51798,P51790	2
+ERAP1-like C-terminal domain [IPR024571]	0.7288314622990822	1.4584113122770956	0.1447272044484324	1.0	0.8402162579375394	4	Q9NZ08,P55786	2
+Zinc finger, CHHC-type [IPR012996]	0.8150450730494216	1.4069323005094356	0.1594474644813095	1.0	0.8402162579375394	3	P31943,P55795	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6345295066492669	1.3074030445947928	0.1910758638765821	1.0	0.8421914187143529	7	O15228,Q8NF37,Q9NUQ2	3
+FAD dependent oxidoreductase [IPR006076]	0.6928424933372457	1.306506761573348	0.1913802811429346	1.0	0.8421914187143529	4	Q9H9P8,Q96CU9	2
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.6540852649789135	1.270327744521074	0.2039679093302133	1.0	0.8421914187143529	5	Q14914	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8881292728402745	1.2573010463511751	0.2086446452514172	1.0	0.8421914187143529	2	Q9NVI7	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.7747394742578706	1.2502322982816136	0.2112147015161825	1.0	0.8421914187143529	3	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.7747394742578706	1.2502322982816136	0.2112147015161825	1.0	0.8421914187143529	3	Q13505	1
+Elp3/MiaB/NifB [IPR006638]	0.7708788741466344	1.2352459972184195	0.2167389651986062	1.0	0.8421914187143529	3	Q5VV42	1
+Radical SAM [IPR007197]	0.7708788741466344	1.2352459972184195	0.2167389651986062	1.0	0.8421914187143529	3	Q5VV42	1
+Fatty acid hydroxylase [IPR006694]	0.8803604723430549	1.2269378692583002	0.219845943865004	1.0	0.8421914187143529	2	Q15800	1
+Prenylcysteine lyase [IPR010795]	0.8781852082038426	1.2184482997508863	0.2230536601220152	1.0	0.8421914187143529	2	Q9UHG3	1
+Cyclin-like [IPR013763]	0.6682002923604455	1.2022777645948788	0.2292559288383113	1.0	0.8421914187143529	4	Q00403,O95067	2
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8713486637663055	1.191804689711498	0.2333378364987073	1.0	0.8421914187143529	2	O15254	1
+Ovarian carcinoma immunoreactive antigen domain [IPR009764]	0.8666873834679938	1.173674037411519	0.2405256132684603	1.0	0.8545278158183705	2	Q9NX40	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.8645121193287655	1.1652236090008827	0.2439284914777324	1.0	0.856215299320434	2	P23786	1
+BRICHOS domain [IPR007084]	0.8567433188315599	1.135102344859353	0.256332439207827	1.0	0.8654190563453656	2	Q9Y287	1
+Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]	0.8480422622746843	1.1014856955486605	0.2706853267727434	1.0	0.8857213067313515	2	Q9NZ45	1
+Iron-binding zinc finger, CDGSH type [IPR018967]	0.8480422622746843	1.1014856955486605	0.2706853267727434	1.0	0.8857213067313515	2	Q9NZ45	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.7298734686764439	1.0767673178141477	0.2815842295124766	1.0	0.8950950132394042	3	Q9H3P7	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.727696611750066	1.0684048721013708	0.2853379202544557	1.0	0.895651798025746	3	Q9UL46,P61289	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.727696611750066	1.0684048721013708	0.2853379202544557	1.0	0.895651798025746	3	Q9UL46,P61289	2
+Acyltransferase, C-terminal domain [IPR032098]	0.8337476693598375	1.0465717517016062	0.2952971360458614	1.0	0.8976114963407141	2	Q9NUQ2	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.596134304254468	1.011248280619427	0.3118976130562734	1.0	0.8976114963407141	5	Q9UKU0,P33121	2
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.8203853325046633	0.9956486772817223	0.3194208747459326	1.0	0.8976114963407141	2	P04066	1
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.8197638284648803	0.9932909012242273	0.3205682103521812	1.0	0.8976114963407141	2	Q6BDS2	1
+AMP-dependent synthetase/ligase [IPR000873]	0.5678497053667645	0.9907842835305576	0.32179092518936	1.0	0.8976114963407141	7	Q9UKU0,P33121	2
+Major facilitator superfamily domain [IPR020846]	0.5834212476639233	0.9546575537596534	0.3397509016954838	1.0	0.9192412369440628	5	P53985,Q9H2V7,P11166	3
+Oxidoreductase, N-terminal domain [IPR041694]	0.8091982597886744	0.9533686427111544	0.3404033233992338	1.0	0.9192412369440628	2	Q14914	1
+GYF domain [IPR003169]	0.8079552517091386	0.9486926747050202	0.3427769407618517	1.0	0.920707776733674	2	O95400	1
+TRAM domain [IPR002792]	0.8051584835301239	0.9381885717782042	0.3481475103582516	1.0	0.920707776733674	2	Q5VV42	1
+Methylthiotransferase, N-terminal [IPR013848]	0.8051584835301239	0.9381885717782042	0.3481475103582516	1.0	0.920707776733674	2	Q5VV42	1
+Diacylglycerol kinase, catalytic domain [IPR001206]	0.7952144188937258	0.9010386525893868	0.3675677687920404	1.0	0.9304099916079188	2	Q9NRA0	1
+Tim44-like domain [IPR007379]	0.7893101305158483	0.8791365758693278	0.3793272282169424	1.0	0.9309612766241904	2	Q9BRJ2	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.5774253731343223	0.8225876647422834	0.410742515695548	1.0	0.9526103296984058	4	P06576,P38606,P25705	3
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.5774253731343223	0.8225876647422834	0.410742515695548	1.0	0.9526103296984058	4	P06576,P38606,P25705	3
+LEM-like domain [IPR013146]	0.7722187694219815	0.8164633704425995	0.4142351652421578	1.0	0.9526103296984058	2	P42167	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.7715972653822043	0.8142062678449337	0.4155267953845543	1.0	0.9526103296984058	2	P13674	1
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.7712865133623408	0.8130783254364805	0.4161731524670933	1.0	0.9526103296984058	2	Q9Y305	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.5743372797795732	0.8099641291409609	0.4179607923811022	1.0	0.9526103296984058	4	Q9Y5X3	1
+SUN coiled coil domain 2 [IPR040994]	0.7632069608452279	0.7838981631193688	0.4330998676983459	1.0	0.9549356729642968	2	Q9UH99	1
+DDHD domain [IPR004177]	0.7579241765071288	0.7649774126309632	0.4442849948470959	1.0	0.959899954297524	2	O94830	1
+SET domain [IPR001214]	0.5396384196210667	0.7620533438266233	0.4460281673051764	1.0	0.959899954297524	5	Q03164,Q9H7B4	2
+NOPS [IPR012975]	0.6456325769350328	0.7606365085933665	0.4468742072023011	1.0	0.959899954297524	3	Q15233,P23246	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.5142381277593382	0.7380802183543944	0.4604657038004189	1.0	0.959899954297524	7	Q03518,P08183,P33897,O75027	4
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.748290863890616	0.7308194709710376	0.4648894288713323	1.0	0.959899954297524	2	P49841	1
+Major sperm protein (MSP) domain [IPR000535]	0.6363071184333187	0.7270186431863307	0.4672145351527881	1.0	0.959899954297524	3	Q9P0L0,Q8NHP6	2
+Cyclin, C-terminal domain [IPR004367]	0.6252393407182494	0.6876261590255507	0.4916882306985675	1.0	0.959899954297524	3	O95067	1
+Cyclin, N-terminal [IPR006671]	0.6252393407182494	0.6876261590255507	0.4916882306985675	1.0	0.959899954297524	3	O95067	1
+Armadillo repeat-containing domain [IPR006911]	0.7299564947172213	0.6671563149341259	0.5046722918354885	1.0	0.959899954297524	2	Q9UH62	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.6185615501226277	0.6641480201173959	0.5065955783431619	1.0	0.959899954297524	3	P13674	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.7265382224984303	0.6554988936497207	0.5121465984823497	1.0	0.959899954297524	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.7265382224984303	0.6554988936497207	0.5121465984823497	1.0	0.959899954297524	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.7265382224984303	0.6554988936497207	0.5121465984823497	1.0	0.959899954297524	2	A1L0T0	1
+CARG-binding factor, N-terminal [IPR012956]	0.7243629583592353	0.6481173583479449	0.5169090477002707	1.0	0.959899954297524	2	Q14103	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.721255438160354	0.637623060659627	0.523719080484321	1.0	0.959899954297524	2	O43390	1
+FCP1 homology domain [IPR004274]	0.6106454831025752	0.6366212540188497	0.5243715775163509	1.0	0.959899954297524	3	Q8WVY7	1
+BSD domain [IPR005607]	0.7128651336233472	0.6095967001527876	0.5421289980834103	1.0	0.9680724878484024	2	Q9NW68	1
+Zinc finger, TFIIB-type [IPR013137]	0.711000621504045	0.6034316684495161	0.5462215601555949	1.0	0.968426515865782	2	Q00403	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4797086036510408	0.5519851945019354	0.5809584970363608	1.0	0.9859275692048493	9	O15254,Q15067	2
+Tudor domain [IPR002999]	0.4762590530483317	0.5501663798152481	0.5822052609279831	1.0	0.9867295279956309	8	Q16637,Q9Y2W6,Q14739	3
+Band 7 domain [IPR001107]	0.4748200845554601	0.5437176587499896	0.5866357787780918	1.0	0.9879563926917108	8	P27105,Q99623,Q14254	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.4877489130522049	0.5428168983319773	0.5872558772375767	1.0	0.9879563926917108	5	P13674	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.4877489130522049	0.5428168983319773	0.5872558772375767	1.0	0.9879563926917108	5	P13674	1
+WH2 domain [IPR003124]	0.6920447482908431	0.5421449789402749	0.5877186352333821	1.0	0.9879563926917108	2	Q9Y6W5	1
+Phox homology [IPR001683]	0.4860938536009268	0.5417833382915616	0.5879677707780797	1.0	0.9879563926917108	12	Q9Y2I1,Q96S38,Q9Y5X3	3
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.6864512119328849	0.5245730235036413	0.5998800439675729	1.0	0.9922326021333896	2	Q9BQ67	1
+CRA domain [IPR013144]	0.6848974518334401	0.5197356876430475	0.603247809507165	1.0	0.9922326021333896	2	Q96S59	1
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.6848974518334401	0.5197356876430475	0.603247809507165	1.0	0.9922326021333896	2	Q96S59	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.5694746658377341	0.49971733039666	0.6172741278478984	1.0	0.9922326021333896	3	O43823,Q5BKZ1	2
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.6783716594157926	0.4996324114502812	0.6173339315991142	1.0	0.9922326021333896	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.6783716594157926	0.4996324114502812	0.6173339315991142	1.0	0.9922326021333896	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.6783716594157926	0.4996324114502812	0.6173339315991142	1.0	0.9922326021333896	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6783716594157926	0.4996324114502812	0.6173339315991142	1.0	0.9922326021333896	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.6783716594157926	0.4996324114502812	0.6173339315991142	1.0	0.9922326021333896	2	A0FGR8	1
+SUN domain [IPR012919]	0.5684213504293705	0.4963717399171443	0.6196321597260681	1.0	0.9922326021333896	3	Q9UH99	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.6765071472964389	0.4939532163828333	0.6213392200250025	1.0	0.9922326021333896	2	Q8IWA4	1
+1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]	0.676196395276577	0.4930095220566804	0.6220058592416975	1.0	0.9922326021333896	2	Q99943	1
+L27 domain, C-terminal [IPR014775]	0.4712286158631346	0.4764050518946808	0.633785836261664	1.0	0.9922326021333896	5	Q9NZW5,Q8N3R9,O14936,Q14168	4
+L27 domain [IPR004172]	0.4712286158631346	0.4764050518946808	0.633785836261664	1.0	0.9922326021333896	5	Q9NZW5,Q8N3R9,O14936,Q14168	4
+Rpn11/EIF3F, C-terminal [IPR024969]	0.4763681592039721	0.4343508436101721	0.6640336878958164	1.0	0.9922326021333896	4	O00303,O00487,Q7L5N1	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.4763084513951132	0.4341428378628595	0.6641847195125408	1.0	0.9922326021333896	4	P08670	1
+EF hand associated, type-1 [IPR013566]	0.6482287134866438	0.4115858978440324	0.6806429696724545	1.0	0.995950199320386	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.6482287134866438	0.4115858978440324	0.6806429696724545	1.0	0.995950199320386	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.6482287134866438	0.4115858978440324	0.6806429696724545	1.0	0.995950199320386	2	Q8IXI1	1
+Post-SET domain [IPR003616]	0.4674779325191492	0.4037597646687534	0.6863893864502575	1.0	0.995950199320386	4	Q03164	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.643878185208213	0.3995793823874828	0.6894663446476486	1.0	0.995950199320386	2	Q9UHQ9	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.6398384089496676	0.3885987302966466	0.697573006177562	1.0	0.995950199320386	2	Q9NRG7	1
+UBX domain [IPR001012]	0.4315134628514483	0.3847672481876431	0.7004098666181693	1.0	0.995950199320386	6	Q92575,Q96CS3	2
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.4306171687062805	0.3532173535546936	0.7239254990600035	1.0	0.995950199320386	8	O60313,Q8IWA4	2
+Dynamin, N-terminal [IPR045063]	0.4306171687062805	0.3532173535546936	0.7239254990600035	1.0	0.995950199320386	8	O60313,Q8IWA4	2
+Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]	0.6131137352392789	0.3202401600933194	0.7487862815374815	1.0	0.995950199320386	2	Q9H4A4	1
+Patatin-like phospholipase domain [IPR002641]	0.5056495392728955	0.3149168829408732	0.7528247626008073	1.0	0.995950199320386	3	Q96AD5	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.6013051584835406	0.292528651258954	0.7698824568779941	1.0	0.995950199320386	2	P15880	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.6013051584835406	0.292528651258954	0.7698824568779941	1.0	0.995950199320386	2	P15880	1
+SCP2 sterol-binding domain [IPR003033]	0.495181846440793	0.2885889273560636	0.7728959698412308	1.0	0.995950199320386	3	Q6YN16,P51659	2
+Zinc finger, RanBP2-type [IPR001876]	0.4143109083084504	0.2876838929923483	0.7735887205691854	1.0	0.995950199320386	8	P35637,Q92804,Q01844	3
+Man1/Src1, C-terminal [IPR018996]	0.595711622125555	0.2799595451062602	0.7795085425677584	1.0	0.995950199320386	2	Q9Y2U8	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.41894455256219	0.2668523617372423	0.789582836711596	1.0	0.995950199320386	11	Q9Y680,O95302	2
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.5851460534493588	0.257217156779566	0.7970111402820936	1.0	0.995950199320386	2	O75608	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4104477611940217	0.2288826414178546	0.8189601326103173	1.0	0.995950199320386	4	Q8WVV9,P26599,P14866	3
+Immunoglobulin-like domain [IPR007110]	0.4153920006742462	0.2283215973704798	0.819396235669064	1.0	0.995950199320386	13	P35613,Q9Y639,Q08722	3
+Ribosomal protein L30, N-terminal [IPR012988]	0.5571783716594279	0.2034757045001169	0.8387632334707011	1.0	0.995950199320386	2	P18124	1
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.5571783716594279	0.2034757045001169	0.8387632334707011	1.0	0.995950199320386	2	P18124	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.5571783716594279	0.2034757045001169	0.8387632334707011	1.0	0.995950199320386	2	P18124	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.5556246115599874	0.2007685948362594	0.8408795205886672	1.0	0.995950199320386	2	P42356	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.5540708514605451	0.1980909196612199	0.8429739291261478	1.0	0.995950199320386	2	P10644	1
+Death domain [IPR000488]	0.4518452778575758	0.1935867494273897	0.846499474344476	1.0	0.995950199320386	3	Q13546	1
+Immunoglobulin subtype 2 [IPR003598]	0.3911419000375269	0.1875601499981404	0.8512214674505496	1.0	0.995950199320386	9	Q9Y639	1
+S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]	0.5444375388440158	0.1821456742526255	0.8554684053480348	1.0	0.995950199320386	2	O43865	1
+Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]	0.4367423064967441	0.166069747182589	0.8681020617803801	1.0	0.995950199320386	3	Q14241,P23193	2
+CAP Gly-rich domain [IPR000938]	0.4364314578800159	0.1655345284941737	0.8685232748831893	1.0	0.995950199320386	3	Q14203,Q99426	2
+Thioesterase domain [IPR006683]	0.5264139216905036	0.1553275749720427	0.8765630777422979	1.0	0.995950199320386	2	O00154	1
+Serpin domain [IPR023796]	0.5229956494717347	0.1506790402203417	0.8802289079201002	1.0	0.995950199320386	2	P50454	1
+Zasp-like motif [IPR006643]	0.5205096333126304	0.1473846861433071	0.8828283922080566	1.0	0.995950199320386	2	O00151	1
+Kinesin-associated [IPR032405]	0.5149160969546381	0.1402360730911706	0.8884734713009239	1.0	0.995950199320386	2	Q15058	1
+ZU5 domain [IPR000906]	0.5114978247358755	0.1360454549284999	0.8917853471484407	1.0	0.995950199320386	2	Q12955	1
+Syntaxin, N-terminal domain [IPR006011]	0.4159154491762556	0.1329865602486186	0.8942040094548194	1.0	0.995950199320386	3	O15400,Q12846	2
+Kinesin-like [IPR022164]	0.5080795525171059	0.1319882835932526	0.8949935590070233	1.0	0.995950199320386	2	Q12756	1
+Dehydrogenase, E1 component [IPR001017]	0.4987569919204624	0.1215899044241196	0.903223809264852	1.0	0.995950199320386	2	P08559	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.4978247358607959	0.1206028656525823	0.9040055989511262	1.0	0.995950199320386	2	Q92945	1
+F-BAR domain [IPR031160]	0.4962709757613579	0.1189788155184052	0.9052921393164852	1.0	0.995950199320386	2	Q9UKS6	1
+FCH domain [IPR001060]	0.4962709757613579	0.1189788155184052	0.9052921393164852	1.0	0.995950199320386	2	Q9UKS6	1
+Domain of unknown function DUF4217 [IPR025313]	0.4044140503574782	0.1171108900562861	0.9067721801045064	1.0	0.995950199320386	3	Q8NHQ9,Q9NVP1	2
+Alpha-D-phosphohexomutase, C-terminal [IPR005843]	0.4863269111249355	0.1091961679752961	0.9130468996486596	1.0	0.995950199320386	2	O95394	1
+CID domain [IPR006569]	0.3559427504667038	0.1080712407378376	0.9139391810802816	1.0	0.995950199320386	6	O95104,Q9NQG5,O15042,Q8IWX8,Q96P16	5
+Class II aldolase/adducin N-terminal [IPR001303]	0.4794903666873918	0.1030669936529455	0.9179098007283524	1.0	0.995950199320386	2	Q9UEY8	1
+Signal recognition particle SRP54, helical bundle [IPR013822]	0.4776258545680696	0.1014771564878718	0.9191716904210424	1.0	0.995950199320386	2	P08240	1
+Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]	0.4776258545680696	0.1014771564878718	0.9191716904210424	1.0	0.995950199320386	2	P08240	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.3882499222878535	0.0975973400683779	0.9222520367416414	1.0	0.995950199320386	3	P52888,Q99797	2
+RAP domain [IPR013584]	0.4714108141703046	0.0964239438056563	0.9231838763163128	1.0	0.995950199320386	2	Q7L8L6	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.4714108141703046	0.0964239438056563	0.9231838763163128	1.0	0.995950199320386	2	Q7L8L6	1
+FAST kinase leucine-rich [IPR010622]	0.4714108141703046	0.0964239438056563	0.9231838763163128	1.0	0.995950199320386	2	Q7L8L6	1
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.4583592293349999	0.0869941231634631	0.93067618343478	1.0	0.995950199320386	2	Q9NP81	1
+ELMO domain [IPR006816]	0.4512119328775776	0.0824702083070475	0.9342728079409728	1.0	0.995950199320386	2	Q8IZ81	1
+Zinc finger, MYND-type [IPR002893]	0.4462399005593693	0.0795742985473799	0.9365758371669392	1.0	0.995950199320386	2	Q9H7B4	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.4425108763207094	0.0775320277699816	0.9382003134717642	1.0	0.995950199320386	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.4425108763207094	0.0775320277699816	0.9382003134717642	1.0	0.995950199320386	2	P40939	1
+CTP synthase, N-terminal [IPR017456]	0.4412678682411613	0.0768752929529563	0.9387227527362458	1.0	0.995950199320386	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.4412678682411613	0.0768752929529563	0.9387227527362458	1.0	0.995950199320386	2	Q9NRF8	1
+BAT2, N-terminal [IPR009738]	0.4390926041019444	0.0757543205172961	0.9396145585882144	1.0	0.995950199320386	2	Q9Y520	1
+Cyclic nucleotide-binding domain [IPR000595]	0.3379975124378018	0.073896450571785	0.941092780162285	1.0	0.995950199320386	4	P13861,Q9Y4G8,P10644	3
+Ribosomal protein/NADH dehydrogenase domain [IPR007741]	0.4350528278433987	0.0737660360613593	0.9411965526661152	1.0	0.995950199320386	2	P82663	1
+Sorting nexin, N-terminal [IPR005329]	0.4316345556246265	0.0721758607951046	0.9424619553559456	1.0	0.995950199320386	2	O60749	1
+Survival motor neuron [IPR010304]	0.4279055313859689	0.0705341980674998	0.9437684821996573	1.0	0.995950199320386	2	Q16637	1
+Rap/Ran-GAP domain [IPR000331]	0.4269732753263077	0.0701385640630198	0.944083372583478	1.0	0.995950199320386	2	Q86X10	1
+BTB/POZ domain [IPR000210]	0.3345771144278547	0.0686475587066546	0.9452701617545644	1.0	0.995950199320386	4	Q08380,Q96CX2,Q9NXV2	3
+FYVE zinc finger [IPR000306]	0.3345771144278543	0.0686475587066541	0.9452701617545648	1.0	0.995950199320386	4	Q7Z3T8,Q96T51,O14964	3
+Zinc finger, FYVE-related [IPR017455]	0.3345771144278543	0.0686475587066541	0.9452701617545648	1.0	0.995950199320386	4	Q7Z3T8,Q96T51,O14964	3
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.4129894344313315	0.0648700968575291	0.94827742967972	1.0	0.995950199320386	2	Q96CX2	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.40522063393413	0.0624403040599694	0.9502121995615808	1.0	0.995950199320386	2	Q93009	1
+PITH domain [IPR010400]	0.3990055935363695	0.0607256427649706	0.9515777093898898	1.0	0.995950199320386	2	O43396	1
+Rhodanese-like domain [IPR001763]	0.3380038829442391	0.0571972606050651	0.9543880603103788	1.0	0.995950199320386	5	P40818,P25325	2
+Immunoglobulin subtype [IPR003599]	0.3536413419530765	0.0535871412467901	0.957264101590459	1.0	0.995950199320386	10	Q9Y639	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.3338681605683319	0.0535700374100525	0.9572777289039508	1.0	0.995950199320386	3	P51809	1
+Longin domain [IPR010908]	0.3338681605683319	0.0535700374100525	0.9572777289039508	1.0	0.995950199320386	3	P51809	1
+Exosome complex component, N-terminal domain [IPR025721]	0.3446239900559459	0.0521766156225736	0.9583879655775356	1.0	0.995950199320386	2	Q9Y3B2	1
+Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]	0.3244251087632197	0.0509258845609479	0.959384579370024	1.0	0.995950199320386	2	P21399	1
+Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]	0.3244251087632197	0.0509258845609479	0.959384579370024	1.0	0.995950199320386	2	P21399	1
+USP8 dimerisation domain [IPR015063]	0.3067122436295957	0.0502835027950429	0.9598964700008696	1.0	0.995950199320386	2	P40818	1
+Peptidase M28 [IPR007484]	0.3183089835250278	0.0461227312685674	0.963212428353334	1.0	0.995950199320386	3	Q7Z2K6,Q969V3	2
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.3176872862915794	0.0458640100283315	0.9634186398116652	1.0	0.995950199320386	3	P48147,Q4J6C6	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.2945513569033631	0.0380748533903654	0.969628000855387	1.0	0.9990225441311162	3	P21912	1
+Peptidase M16, C-terminal [IPR007863]	0.3306867821746443	0.0251576400631313	0.9799292245849404	1.0	1.0	7	Q10713	1
+Peptidase M16, N-terminal [IPR011765]	0.3306867821746443	0.0251576400631313	0.9799292245849404	1.0	1.0	7	Q10713	1
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3349543655834615	0.0029998458446912	0.9976064729056544	1.0	1.0	10	Q03518,P08183,P33897,O75027	4

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin [IPR002453]", "1": "Tubulin [IPR000217]", "2": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin [IPR002453]", "1": "Tubulin [IPR000217]", "2": "Mitochondrial carrier protein [IPR002067]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}