diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9d490acc8c6605e0c0733e96ef365e424bed0f4c --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca71291e1c0dc0fba8a9331e8e2f33b5fd6048942bebb0f3bbe5b3fb355effa8 +size 75542 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..821650ffb8de446115546dd0d763c4c00f7787b1 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.508771929824561 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..05e15a0218c95be400add6d0fce6813946e420ad --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..393d67ea2228d8a0edb1225a3354b2da0d4f34d6 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Serine carboxypeptidase, serine active site [IPR018202] 0.9664283493938438 1.7825411912754807 0.0746610202450503 0.988000894913337 0.2492940841252635 3 Q9H3G5,P10619 2 +Histidine acid phosphatase active site [IPR033379] 0.9136109384710944 1.0865083004233045 0.2772541706300853 0.9999999908340208 0.5267829241971621 2 Q9NPH0 1 +Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.8660658794282167 0.915217093567991 0.3600776726613151 0.9999999999911028 0.6036596276969106 2 Q7LG56 1 +Peptidase S9, serine active site [IPR002471] 0.4984462399005683 0.0677261646104475 0.9460036207791548 1.0 0.9804037524438516 2 P48147 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..393b65b9b53cd296b225fc89734a612e8089d1e0 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "CPVL", "CTSA", "PREP", "RRM2B"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3c5144a6d0db9d8e393d38b825479d1064ce6d21 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c80108360f31e20d0d5ae3663ab8d32d7f1278a10fd87cd98a0903313aec0a13 +size 147859 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ce2d9357dc6a6884c71796ac8ad2a2c335977cd4 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:093bb5e99a81ef39f0229ef125b944feb87e5247ccb98908f91345a402a7f0d4 +size 73626 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f4a48a3b442548207d9b90cc4303e9fcd0425651 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Peptidase M16, zinc-binding site [IPR001431] 2 5 2.313795026612107 0.0206789683137311 1.730582524271845 5.0 0.6776547957610433 0.4740055886775391 1.2118895823030245 0.0 0.8079860258854747 0.314626832259423 0.0002685484719454 1.0 1.0 0.0055254488719224 0.0010568895936515 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d9b72b8e3c64996bdb9e8b87084bad0af58d2fc6 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 32, + "title": "Average number of proteins per term", + "value": 4.5 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9ca0e22b0f9d68417d4ef90dc3a8d918e29bee1a --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..28fc04ce01dff2e27e67a255fe2ff78646a701ac --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase M16, zinc-binding site [IPR001431] 0.8847662535282672 2.313795026612107 0.0206789683137311 0.4876076873603735 0.1323453972078795 5 Q10713,P22695 2 +Beta tubulin, autoregulation binding site [IPR013838] 0.646147672788906 1.498761826334304 0.1339354310326141 0.9899628896721856 0.3896303448221503 7 P68371,Q13509,P04350,Q9BVA1 4 +EF-Hand 1, calcium-binding site [IPR018247] 0.3890003235353017 0.7193464935681821 0.4719274557636743 0.9999999986628048 0.7634011248249627 39 Q9NWM8,Q02818,Q14257,Q9Y680,P41208,P80303 6 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..16f2d9a5918c68d45b895e56d9f13f81f731cecc --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO19", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["CETN2", "FKBP14", "FKBP7", "NUCB1", "NUCB2", "PMPCA", "RCN2", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2d87a456c859f7d763df70f2e8915263713ecf7 --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..284669974a4ba48c47dda7055ee966bb8827892c --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7813b4b29778e4c4954ec731abaa8d59ba52288d74aac922bb207b9b0de93cab +size 191427 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..837365b98c49198dc541e5275dd032248f9753d6 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "Tubulin, conserved site [IPR017975]", "3": "Guanylate kinase, conserved site [IPR020590]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c1b899e6e93a1b6614ee98f64fe25de579f770d7 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2b58db147c1474647ed9c1ba8a3c14d9edd54cc3b72c56e411bb7122f192b58 +size 143166 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d100e2b832caeac9c827bea4937a3a93c9b8d6cc --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e3f1e2f377b716a6d41b83272b29a8c7230549f6b91f6f0769c3003c28b2679 +size 136683 diff --git a/interpro_conserved_site/basic/plot_2.png b/interpro_conserved_site/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..51032ee3b21d3badf11cc5303db15a1d2581c8b1 --- /dev/null +++ b/interpro_conserved_site/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0cd4d22cecf97be9ac91d63985998290c7fe2c8f03a5e7497ddfba75b470c036 +size 132796 diff --git a/interpro_conserved_site/basic/plot_3.png b/interpro_conserved_site/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5abc63fb580cbbb37c3b5dcaa0171d1e5e842e71 --- /dev/null +++ b/interpro_conserved_site/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7377c9d5630657bc4c53b59aa211e3b98a4b7602f714ba6c6866b77e0aac165e +size 153212 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cbfd7392d73cdf48497f9156b90c4ae6d818a09c --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:05d9378c0de4410d9282704f2fdccb61c3eb607c189a45459340b99d6a64156b +size 86318 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0692a0ab528444cfcafb205285d73b83704dad34 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.234349168086861 0.0254601075386344 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0028755778106474 0.0479914252810258 0.0938999510605359 0.0229613270793894 5.436360967141595e-05 +Syntaxin/epimorphin, conserved site [IPR006012] 2 8 2.234188050684015 0.0254707023443236 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 0.0064033235801391 1.0 0.1203280145079081 0.0379575415698398 0.0225979674873623 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..afb5d160e6abf75e6a388e2ceec0ed2f5f3905c8 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 273, + "title": "Average number of proteins per term", + "value": 2.58974358974359 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..417fdff74ef4dcee87f338c71eec92644f66e86d --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1d27e21a29039e86ee3889999bb8a0c891457abc --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Proteasome beta-type subunit, conserved site [IPR016050] 0.7730992528416881 2.2343491680868612 0.0254601075386344 0.9991244183047322 0.2923526080479657 8 P49721,P28070,P20618,P28074,P28072 5 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7730655198117725 2.234188050684015 0.0254707023443236 0.999127013145608 0.2923526080479657 8 Q9P2W9,O60499 2 +Tetraspanin, conserved site [IPR018503] 0.9459123406900792 1.706464136438597 0.0879216981132899 0.999999999987732 0.486266049431425 3 O43657,O60637 2 +Intermediate filament protein, conserved site [IPR018039] 0.6404541662383724 1.5779954314427866 0.1145666593601864 0.9999999999999962 0.5686672364605615 8 P07196,P07197,Q03252,Q16352,P08670 5 +Mini-chromosome maintenance, conserved site [IPR018525] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.5954754224672094 6 Q14566,P25205,P49736 3 +Tubulin, conserved site [IPR017975] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.5954754224672094 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Thioredoxin, conserved site [IPR017937] 0.5382537124515046 1.3768652094353204 0.1685539252454422 1.0 0.6035171725209099 12 Q9H3N1,Q96JJ7,Q9H1E5 3 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8246583828887826 1.25257523720809 0.2103603314321018 1.0 0.6525951191018614 3 Q8N4Q0 1 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.906774394033561 1.0615888152566837 0.2884223935068983 1.0 0.734863949864907 2 Q9BTY2 1 +Sterol reductase, conserved site [IPR018083] 0.8523927905531207 0.8670110591486583 0.3859359502551789 1.0 0.8296103497611326 2 Q14739 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.7967681789931663 0.6778642529468616 0.4978577670888873 1.0 0.8731492022257699 2 P11279 1 +Methylthiotransferase, conserved site [IPR020612] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.92439071197331 2 Q5VV42 1 +ABC transporter-like, conserved site [IPR017871] 0.4111541577629098 0.5070595621835099 0.6121130271979989 1.0 0.9559185943989472 10 O75027,P08183 2 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.6821006836544513 0.3444047087538905 0.7305419481625663 1.0 0.9657910906995332 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.6821006836544513 0.3444047087538905 0.7305419481625663 1.0 0.9657910906995332 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.6821006836544513 0.3444047087538905 0.7305419481625663 1.0 0.9657910906995332 2 Q07820 1 +Mrp, conserved site [IPR000808] 0.6730888750776961 0.322701269845695 0.7469214903596411 1.0 0.9657910906995332 2 Q9Y5Y2 1 +Actin, conserved site [IPR004001] 0.6637663144810526 0.3010781127447693 0.7633549306271492 1.0 0.9662883416316188 2 P61163 1 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6522684897451922 0.2756049852373609 0.7828514802520401 1.0 0.969151424589004 2 Q16836 1 +Oxysterol-binding protein, conserved site [IPR018494] 0.4284825870646682 0.2388936149154728 0.8111880767968862 1.0 0.9808200903469538 4 Q9BXB4,P22059,Q9BZF1 3 +UbiE/COQ5 methyltransferase, conserved site [IPR023576] 0.6196395276569395 0.2108070429503086 0.833037842564105 1.0 0.9880594732118968 2 O43159 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.4802611128380571 0.1713422479124139 0.863954662588599 1.0 0.9922042556917896 3 P09429,P26583 2 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.354002562798601 0.13919734714711 0.8892942047668415 1.0 0.9936422891736566 7 P30837,P51648,Q02252 3 +Actin/actin-like conserved site [IPR020902] 0.4597451041342927 0.1371244336916003 0.890932439598566 1.0 0.9936422891736566 3 P61160,P61163 2 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4261734535281377 0.0919069537222774 0.926771966577046 1.0 0.9994334820820256 3 Q9BXS5,Q96CW1 2 +Heat shock protein Hsp90, conserved site [IPR019805] 0.4143612060926449 0.0790702144543827 0.9369767747379752 1.0 0.9994334820820256 3 P07900,P14625 2 +Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.481354878806728 0.058303567505583 0.953506825892736 1.0 1.0 2 P06730 1 +Profilin conserved site [IPR027310] 0.4449968924798187 0.0444541761679887 0.9645423779606166 1.0 1.0 2 P35080 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4353635798632783 0.0419385785637804 0.9665476621919504 1.0 1.0 2 O60568 1 +Macrophage migration inhibitory factor, conserved site [IPR019829] 0.4322560596644014 0.0412126926328908 0.9671263350125628 1.0 1.0 2 P14174 1 +Guanylate kinase, conserved site [IPR020590] 0.3136278780335957 0.0221093140928971 0.982360756721395 1.0 1.0 6 Q5T2T1,O14936,Q9NZW5,Q14168,Q8N3R9 5 +Zinc finger, RING-type, conserved site [IPR017907] 0.3081936299252925 0.0150130648963117 0.988021757277507 1.0 1.0 9 O60858 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..053ebd618317b9f1820889d3647bff0a47839e87 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK1", "RIOK2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ACTR1A", "ACTR2", "ALDH1B1", "ALDH3A2", "ALDH6A1", "AP1M1", "AP2M1", "CASK", "CDKAL1", "EIF4E", "FUCA2", "HADH", "HMGB1", "HMGB2", "HSP90AA1", "HSP90B1", "INA", "LAMP1", "LBR", "LMNB2", "MCL1", "MCM2", "MCM3", "MCM6", "MIF", "MPP2", "MPP5", "MPP6", "MPP7", "NEFL", "NEFM", "NUBP2", "OSBP", "OSBPL11", "OSBPL8", "PFN2", "PLOD3", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RRP8", "STX10", "STX18", "TMX1", "TMX3", "TMX4", "TRIM13", "TSPAN3", 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https://git-lfs.github.com/spec/v1 +oid sha256:b83564db44273e647bccc4e2172d04783d9e989691cafd629f51dc7411fee82f +size 135448 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b91609c8306b7ae1ac86f8acfd256159a48f9e5c --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e91595ffa2ffc248728da26e512822baec88488ee6e647f592451c1e092d5ca +size 182361 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..355bcf0c4218d4464d8a89a6bdb9561a15978e6d --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Aminopeptidase N-like , N-terminal domain [IPR045357] 3 6 2.3019189181843065 0.0213397451280803 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0014043590152869 1.0 0.0758460972151271 0.0007102815399137 0.0003286021100258 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 3 6 2.3019189181843065 0.0213397451280803 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0014043590152869 1.0 0.0758460972151271 0.0007102815399137 0.0003286021100258 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 5 6 2.1934801417141827 0.0282728038113517 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0050382705358123 0.0573151884822011 0.0058956460302812 0.032628233248221 0.0019884945269669 +Peptidase M16, N-terminal [IPR011765] 2 7 2.115168144752169 0.0344156189151507 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 0.0008979538364946 1.0 1.0 0.0112385866308786 0.0034377129995212 +Peptidase M16, C-terminal [IPR007863] 2 7 2.115168144752169 0.0344156189151507 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 0.0008979538364946 1.0 1.0 0.0112385866308786 0.0034377129995212 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..34573a171c3784aafc2292b692100d4d129eacc1 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 2549, + "title": "Average number of proteins per term", + "value": 2.1439780306002354 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ea19686347c22be9bf91d1d3c51f60309c8f727a --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2ed582de986a8173460fb617f97faa99ce50804e --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,186 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.843332381192831 2.3019189181843065 0.0213397451280803 1.0 0.4496870741101658 6 Q9NZ08,Q9UIQ6,P55786 3 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.843332381192831 2.3019189181843065 0.0213397451280803 1.0 0.4496870741101658 6 Q9NZ08,Q9UIQ6,P55786 3 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8186060983198604 2.1934801417141827 0.0282728038113517 1.0 0.4496870741101658 6 O15173,O43169,Q8WUJ1,Q9UMX5,O00264 5 +Peptidase M16, N-terminal [IPR011765] 0.7749507163238163 2.115168144752169 0.0344156189151507 1.0 0.4496870741101658 7 Q10713,P22695 2 +Peptidase M16, C-terminal [IPR007863] 0.7749507163238163 2.115168144752169 0.0344156189151507 1.0 0.4496870741101658 7 Q10713,P22695 2 +ERAP1-like C-terminal domain [IPR024571] 0.8777788596785823 1.9906485767592448 0.0465195357999814 1.0 0.4496870741101658 4 Q9NZ08,P55786 2 +GOLD domain [IPR009038] 0.7619788425637942 1.9400926804479093 0.0523684274072966 1.0 0.4552740288463645 6 Q9Y3B3,Q9BVK6,Q9H3P7,Q15363,P49755 5 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.861315780839336 1.9245937874769516 0.0542801972344906 1.0 0.4552740288463645 4 Q15629,Q96CP7 2 +Reticulon [IPR003388] 0.8550995024875598 1.899548842968218 0.0574923510853835 1.0 0.4557801861391966 4 Q9NQC3,O75298,O95197 3 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7828926905132111 1.880923714687644 0.0599822967609045 1.0 0.4557801861391966 5 Q9HD20,P05023,P98194,P16615 4 +CBS domain [IPR000644] 0.7653511395368592 1.804428544124092 0.0711641516551075 1.0 0.4781837388700992 5 P51798,Q8NE01 2 +FAD dependent oxidoreductase [IPR006076] 0.8233966560537938 1.7709772870204394 0.0765644787791164 1.0 0.4781837388700992 4 Q96CU9 1 +Polyketide synthase, enoylreductase domain [IPR020843] 0.7446143160090188 1.7133162891185607 0.0866543672534532 1.0 0.4886769516129474 5 Q14914,Q8N4Q0 2 +Peptidase M28 [IPR007484] 0.931935155934204 1.654453068978288 0.098035491381951 1.0 0.5103419714106551 3 Q969V3 1 +LEM domain [IPR003887] 0.69212180807193 1.6183096224203657 0.105595888009256 1.0 0.5188524090797302 6 P50402,Q86XL3,P42167 3 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7826492537313409 1.6038387414013755 0.1087496025698822 1.0 0.5210577762229882 4 P05023,P98194,P16615 3 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7826492537313409 1.6038387414013755 0.1087496025698822 1.0 0.5210577762229882 4 P05023,P98194,P16615 3 +N-acetylgalactosaminyltransferase [IPR045885] 0.7819694196187692 1.6010342252601455 0.1093693389064629 1.0 0.522064503506693 4 Q8N4A0 1 +Post-SET domain [IPR003616] 0.7771415065138869 1.5811040897724284 0.1138542397820145 1.0 0.5275815439783621 4 Q03164,O96028 2 +Intermediate filament, rod domain [IPR039008] 0.6404541662383724 1.5779954314427866 0.1145666593601864 1.0 0.5275815439783621 8 P07196,P07197,Q03252,Q16352,P08670 5 +Glycosyltransferase 2-like [IPR001173] 0.6782066274547988 1.5531244342715458 0.1203934097075025 1.0 0.534639026732446 6 Q8N4A0 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7646144278606937 1.5292855828054406 0.1261936621242054 1.0 0.5379057604591968 4 P07197,P08670,P07196 3 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.569186073838784 1.5167294075894129 0.1293350163652511 1.0 0.5429168963627622 11 Q9NWM8,Q9Y680,P26885,Q96AY3,P62942,Q5T1M5 6 +MCM OB domain [IPR033762] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.5429168963627622 6 Q14566,P25205,P49736 3 +MCM, AAA-lid domain [IPR041562] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.5429168963627622 6 Q14566,P25205,P49736 3 +MCM N-terminal domain [IPR027925] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.5429168963627622 6 Q14566,P25205,P49736 3 +MCM domain [IPR001208] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.5429168963627622 6 Q14566,P25205,P49736 3 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.5429168963627622 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.5429168963627622 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7590887538803055 1.5063835953313225 0.1319687294606235 1.0 0.5437990810208868 4 Q8N4Q0 1 +Ricin B, lectin domain [IPR000772] 0.6888470686125387 1.465040457614741 0.1429098800025148 1.0 0.5604265909637081 5 Q8N4A0 1 +SET domain [IPR001214] 0.6854202451771615 1.4496529232949404 0.1471553297789831 1.0 0.5694977031608193 5 Q03164,O96028 2 +Tim10-like [IPR004217] 0.873484612993471 1.4357782915314543 0.1510654388898209 1.0 0.5694977031608193 3 Q9Y5J9,P62072 2 +Zinc finger, CHHC-type [IPR012996] 0.8675784892757183 1.4136161237079756 0.1574746445226404 1.0 0.570229331226951 3 P31943,P55795 2 +MRH domain [IPR044865] 0.727637607459319 1.375605349090378 0.1689438497299833 1.0 0.5923492062747283 4 Q13438,P20645 2 +Tudor domain [IPR002999] 0.5996511714429553 1.3678652277774763 0.1713542657580919 1.0 0.5947269265585353 8 Q14739 1 +EXPERA domain [IPR033118] 0.9667495338719658 1.2824174401901325 0.1996962494875813 1.0 0.624423230575425 2 Q15125 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.9608452454940956 1.2605001782324678 0.2074889836363862 1.0 0.6364493613587828 2 Q8IV08 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.824370531551129 1.2514965264640314 0.2107533801631245 1.0 0.6369620030257631 3 O75431,Q13505 2 +Metaxin, glutathione S-transferase domain [IPR033468] 0.824370531551129 1.2514965264640314 0.2107533801631245 1.0 0.6369620030257631 3 O75431,Q13505 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8238945755225329 1.2497129765507713 0.211404415284345 1.0 0.6369620030257631 3 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8238945755225329 1.2497129765507713 0.211404415284345 1.0 0.6369620030257631 3 Q9Y282 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.8078955548647815 1.1898256210632183 0.2341149372288562 1.0 0.6697631593674013 3 O43823,Q5BKZ1 2 +Prenylcysteine lyase [IPR010795] 0.935985083903041 1.1685791392323468 0.2425732370467184 1.0 0.6717784684390785 2 Q9UHG3 1 +Phospholipid/glycerol acyltransferase [IPR002123] 0.5717700117700497 1.12932668300381 0.2587600487441643 1.0 0.6928354666479779 7 Q8NF37,O15228,Q9NUQ2 3 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9220012430080702 1.1171980630200629 0.2639096486310279 1.0 0.7001892293893385 2 A6NIH7 1 +BRICHOS domain [IPR007084] 0.9123679303915412 1.0819714472087163 0.279265215440386 1.0 0.7147058575878956 2 Q9Y287 1 +Syntaxin 6, N-terminal [IPR015260] 0.910192666252325 1.0740383231016484 0.2828055057239798 1.0 0.7157537846244383 2 O60499 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.906774394033561 1.0615888152566837 0.2884223935068983 1.0 0.716334141022957 2 Q9BTY2 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.5074866551283004 1.0491638691750729 0.2941027045939137 1.0 0.7217885424930294 10 O60499 1 +Protein kinase, C-terminal [IPR017892] 0.592904183775347 1.0316996245184724 0.3022128533809449 1.0 0.7242510560785628 5 P31751,Q15418 2 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.897451833436915 1.0277464482562224 0.3040691126066153 1.0 0.7242510560785628 2 O15254 1 +Ras-associating (RA) domain [IPR000159] 0.6433126659937214 1.024290031029358 0.3056983051640949 1.0 0.7242510560785628 4 Q9Y4G8 1 +Zinc finger, RanBP2-type [IPR001876] 0.5293092939528569 1.0006162806793513 0.3170123559988638 1.0 0.737958443325209 8 Q92804,P98175,P35637 3 +ABC transporter type 1, transmembrane domain [IPR011527] 0.5308630612858494 0.9252014890696144 0.3548611090901055 1.0 0.7785428150976204 7 O75027,P08183 2 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.8564325668116795 0.8811951047550342 0.3782122283909155 1.0 0.7960722062917872 2 Q15418 1 +NOPS [IPR012975] 0.7221013366490501 0.8736217257231883 0.3823242906672324 1.0 0.7960722062917872 3 P23246,Q15233 2 +Fatty acid hydroxylase [IPR006694] 0.85425730267245 0.8735512055715008 0.3823627088362555 1.0 0.7960722062917872 2 Q15800 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8440024860161601 0.8377199641222485 0.4021879982907463 1.0 0.8135432990000262 2 Q9NVI7 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8368551895587333 0.8129579505255952 0.4162421672364691 1.0 0.8269690446498518 2 O43390 1 +FCP1 homology domain [IPR004274] 0.6885296860428982 0.754288291426621 0.4506761313766234 1.0 0.8530575417719954 3 Q05D32,Q8WVY7 2 +GYF domain [IPR003169] 0.811995027967684 0.7283547316849925 0.4663964665101874 1.0 0.8714664252945514 2 O95400 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8107520198881315 0.7241926310338275 0.4689474819388213 1.0 0.8739315202806441 2 Q14011 1 +LEM-like domain [IPR013146] 0.8057799875699216 0.7076144687102374 0.4791847052848232 1.0 0.8800013067514514 2 P42167 1 +CARG-binding factor, N-terminal [IPR012956] 0.8014294592914881 0.6932032699201032 0.4881819964018834 1.0 0.8817341175348952 2 Q14103 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.7952144188937018 0.6727752050775152 0.5010903143306771 1.0 0.8859236988533888 2 P23786 1 +EF-hand domain [IPR002048] 0.3735225351754409 0.6230616551965564 0.5332440064274988 1.0 0.9048822049986868 47 Q9NWM8,O95202,Q02818,Q14257,Q8NF37,Q9Y680,O43852,P41208,Q6NUK1,P80303,Q8IYU8,O75071,P14649,O75340 14 +Acyltransferase, C-terminal domain [IPR032098] 0.7762585456805224 0.6117134733216523 0.5407273460682727 1.0 0.9048822049986868 2 Q9NUQ2 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.906008694172174 2 P10321 1 +MHC class I-like antigen recognition-like [IPR011161] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.906008694172174 2 P10321 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.906008694172174 2 P10321 1 +Immunoglobulin C1-set [IPR003597] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.906008694172174 2 P10321 1 +Phox homology [IPR001683] 0.40873925945016 0.5873730117479483 0.5569532153222849 1.0 0.9063341653562482 12 Q9Y2I1,Q96S38 2 +B-box-type zinc finger [IPR000315] 0.4871044451944176 0.5680956022511214 0.5699700537724857 1.0 0.9063341653562482 5 O60858 1 +Histone-binding protein RBBP4, N-terminal [IPR022052] 0.759788688626476 0.5603339632989133 0.5752516654485693 1.0 0.9071421057366008 2 Q9BQ67 1 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4322904204317815 0.5582567746132707 0.5766690570116579 1.0 0.907363843409084 9 Q15067,O15254 2 +TRAM domain [IPR002792] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.9097996921656076 2 Q5VV42 1 +Methylthiotransferase, N-terminal [IPR013848] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.9097996921656076 2 Q5VV42 1 +Cyclic nucleotide-binding domain [IPR000595] 0.519675753615847 0.5342891633495174 0.5931414885010615 1.0 0.9175250000251302 4 Q9Y4G8 1 +Fibronectin type II domain [IPR000562] 0.7470478558110677 0.5217718657587217 0.6018291805933988 1.0 0.9219126089739024 2 Q9UBV2 1 +Tim44-like domain [IPR007379] 0.7433188315724066 0.510694252265409 0.6095651660696935 1.0 0.9249250745686628 2 Q9BRJ2 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.4111541577629098 0.5070595621835099 0.6121130271979989 1.0 0.9249250745686628 10 O75027,P08183 2 +DZF domain [IPR006561] 0.5111940298507414 0.5034700866489286 0.61463380644153 1.0 0.9264941292841276 4 Q12905,Q12906,Q96SI9 3 +Ovarian carcinoma immunoreactive antigen domain [IPR009764] 0.7402113113735013 0.501537933104526 0.6159925882891271 1.0 0.9279935623811968 2 Q9NX40 1 +Major facilitator superfamily domain [IPR020846] 0.4690520886340404 0.4943485282050239 0.6210600583827752 1.0 0.9317605568235366 5 P11166,P53985,Q9H2V7 3 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.6083484995079672 0.4892438090155521 0.6246690973816864 1.0 0.931951061262357 3 P13674 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.726538222498452 0.4620919095000848 0.6440154117906569 1.0 0.9354220274443148 2 Q92945 1 +OCRE domain [IPR041591] 0.7246737103791066 0.4568228005982412 0.6477984160199162 1.0 0.9354220274443148 2 P98175 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4578736467398068 0.449993317599216 0.6527152589543979 1.0 0.9354220274443148 5 P13674,Q32P28 2 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4578736467398068 0.449993317599216 0.6527152589543979 1.0 0.9354220274443148 5 P13674,Q32P28 2 +Immunoglobulin-like domain [IPR007110] 0.3805603871329958 0.4468559750229272 0.6549790528400818 1.0 0.9354220274443148 13 P35613,Q08722,Q9Y639,P10586,P10321 5 +SUN coiled coil domain 2 [IPR040994] 0.7125543816034565 0.4232475545050143 0.672114654209935 1.0 0.9375136458569808 2 Q9UH99 1 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.4488391327802891 0.4149801312858506 0.6781564481137632 1.0 0.9394791984511248 5 Q14914 1 +Lamin tail domain [IPR001322] 0.5781507724258742 0.4001261167112441 0.6890636290846668 1.0 0.9394791984511248 3 Q03252 1 +EB1, C-terminal [IPR004953] 0.7026103169670559 0.3966053688864076 0.6916584928013907 1.0 0.9394791984511248 2 Q15555 1 +ELMO domain [IPR006816] 0.6911124922312067 0.3668718171012023 0.713714634543315 1.0 0.9424143192244904 2 Q96JJ3 1 +Ubiquitin system component CUE [IPR003892] 0.4699777972872611 0.3624515918652466 0.7170145917981467 1.0 0.9430333187227836 4 Q9Y679 1 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.6855189558732206 0.3528381494863346 0.7242097816687387 1.0 0.946326019301995 2 Q9Y305 1 +RBM1CTR [IPR012604] 0.6839651957737801 0.3489912300083848 0.7270958935871055 1.0 0.946326019301995 2 P38159 1 +Rab-GTPase-TBC domain [IPR000195] 0.4614427860696441 0.3353596210860643 0.7373538237605481 1.0 0.9476108388678204 4 Q8TC07,Q9Y3P9,Q66K14 3 +DDHD domain [IPR004177] 0.6774394033561295 0.3330819175301343 0.7390724485278115 1.0 0.9476108388678204 2 O94830 1 +Zinc finger, CCHC-type [IPR001878] 0.4100145632846486 0.3204878234881682 0.7485985594432825 1.0 0.9511726537674616 6 Q9NUD5 1 +Rhodanese-like domain [IPR001763] 0.4223410057308281 0.3172773739083063 0.7510331441468958 1.0 0.9511726537674616 5 P25325 1 +L27 domain, C-terminal [IPR014775] 0.4211634558019329 0.3131274510075179 0.7541838341473339 1.0 0.9511726537674616 5 Q14168,Q8N3R9 2 +L27 domain [IPR004172] 0.4211634558019329 0.3131274510075179 0.7541838341473339 1.0 0.9511726537674616 5 Q14168,Q8N3R9 2 +Exportin-2, central domain [IPR013713] 0.5414982903326164 0.3026490379765985 0.7621573390628611 1.0 0.9527181262595388 3 P55060,O15397 2 +Glycogen synthase kinase 3, catalytic domain [IPR039192] 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 0.9527181262595388 2 P49840 1 +1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552] 0.6619018023617238 0.2968567177211486 0.7665759016090266 1.0 0.9552982690138594 2 O15120 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.5363187322946142 0.2899386369178418 0.771863182565967 1.0 0.9573972614540196 3 Q16134 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.964470983418943 3 P61289 1 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.964470983418943 3 P61289 1 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6522684897451922 0.2756049852373609 0.7828514802520401 1.0 0.964470983418943 2 Q16836 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6522684897451922 0.2756049852373609 0.7828514802520401 1.0 0.964470983418943 2 Q16836 1 +STAT transcription factor, protein interaction [IPR013799] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.964470983418943 2 P40763 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.964470983418943 2 P40763 1 +STAT transcription factor, DNA-binding [IPR013801] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.964470983418943 2 P40763 1 +BSD domain [IPR005607] 0.648850217526423 0.2682919460532742 0.7884746051679421 1.0 0.964470983418943 2 Q96A49 1 +BAG domain [IPR003103] 0.4340796019900411 0.2542980965057716 0.7992652702482599 1.0 0.964470983418943 4 Q9UL15,O95817,O95429 3 +Fzo/mitofusin HR2 domain [IPR006884] 0.6357986326911085 0.2414886085901738 0.8091764443059013 1.0 0.964470983418943 2 Q8IWA4 1 +CAP Gly-rich domain [IPR000938] 0.5144544606776591 0.239446292385386 0.8107595376480747 1.0 0.964470983418943 3 Q14203,Q99426 2 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.6314481044126884 0.2329534068142933 0.8157975863976583 1.0 0.964470983418943 2 Q53H12 1 +Major sperm protein (MSP) domain [IPR000535] 0.505750699409397 0.220823354262834 0.8252299783588524 1.0 0.964470983418943 3 Q9P0L0,Q8NHP6 2 +GRAM domain [IPR004182] 0.5013544559301417 0.2117466878051619 0.8323046622655037 1.0 0.9667630433566512 3 Q66K14 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.4973577867578548 0.2036893979068737 0.8385962277567673 1.0 0.9667941133206692 3 Q06210,Q06203 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.336098657031629 0.2003827840493011 0.8411812227765116 1.0 0.9672515559043248 13 Q9UHX1,P38159,Q14011,Q14498 4 +CID domain [IPR006569] 0.3752333540759134 0.1940567490691666 0.8461314470387411 1.0 0.9688424910282756 6 O15042,Q5VT52,O95104,Q8IWX8,Q9NQG5 5 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4026741293532272 0.1735183963518598 0.8622439690075487 1.0 0.9712151467080168 4 O60749,Q9UNH7,Q9Y5X3 3 +AGC-kinase, C-terminal [IPR000961] 0.3628902641543295 0.1699316268439357 0.8650639082124953 1.0 0.9718148532541432 7 P31751,Q15418 2 +NOT2/NOT3/NOT5, C-terminal [IPR007282] 0.5929148539465618 0.1662546544089056 0.8679565498720567 1.0 0.9743706528194196 2 Q9NZN8 1 +PUA domain [IPR002478] 0.447932856698798 0.1197055552759923 0.9047163995335123 1.0 0.983250755294118 3 O60832,Q9Y221 2 +SH2 domain [IPR000980] 0.3379009654313324 0.1195152036768953 0.904867195575437 1.0 0.983250755294118 9 Q06124,P42224,P46108,P46109,Q7KZ85,P07948,P40763,P62993 8 +Syntaxin, N-terminal domain [IPR006011] 0.4435809760646617 0.1137049466609317 0.909471691088686 1.0 0.983250755294118 3 Q86Y82,Q12846 2 +RNA recognition motif domain [IPR000504] 0.2780570210782648 0.1136234796169271 0.9095362738447288 1.0 0.983250755294118 117 Q99729,Q01085,P35637,Q15233,P51991,O60506,Q07955,Q01844,Q8WUA2,P22626,P62995,P26368,Q14011,Q92804,P52597,Q8WVV9,Q96PK6,Q9GZT3,P55795,Q13242,P98175,O15047,O14979,Q13151,P31943,Q8IZ69,Q16630,Q14498,P31942,Q9UHX1,Q14103,P98179,P23246,Q9BWF3,P84103,O43390,P38159,Q93062 38 +Immunoglobulin subtype 2 [IPR003598] 0.3354379806226274 0.1100632285198403 0.9123592303253882 1.0 0.983250755294118 9 Q9Y639,P10586 2 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.548166563082673 0.108754837191993 0.9133969459653232 1.0 0.983250755294118 2 P43246 1 +EF-hand, Ca insensitive [IPR014837] 0.3700248756218838 0.105049636564315 0.9163364222927096 1.0 0.983250755294118 4 Q13813,O43707,P12814 3 +SKP1 component, POZ domain [IPR016073] 0.5388440024860264 0.099347661625252 0.920862237061054 1.0 0.9840285752630332 2 P63208 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.5323182100683792 0.0932582217996978 0.9256984215599656 1.0 0.9840285752630332 2 O94979 1 +F-BAR domain [IPR031160] 0.526103169670617 0.0878266881438973 0.9300144256515864 1.0 0.9856003648969284 2 Q9UKS6 1 +FCH domain [IPR001060] 0.526103169670617 0.0878266881438973 0.9300144256515864 1.0 0.9856003648969284 2 Q9UKS6 1 +Peptidase M41 [IPR000642] 0.5180236171535259 0.0812851277443105 0.935215201190362 1.0 0.9891549991013414 2 Q9Y4W6 1 +Armadillo repeat-containing domain [IPR006911] 0.5031075201988952 0.0706733820956373 0.9436577058611764 1.0 0.9943710178752124 2 Q9UH62 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.3470149253731289 0.06673222107207 0.9467948827693264 1.0 0.9972645273466996 4 O00487,Q7L5N1,O00303 3 +Glutathione S-transferase, N-terminal [IPR004045] 0.3274312436507892 0.0660443820818814 0.94734249077293 1.0 0.997429165212804 8 P78417 1 +Death domain [IPR000488] 0.3972645321728421 0.0631467763933716 0.949649626420862 1.0 0.9994454573686116 3 Q13546,Q12955 2 +ZU5 domain [IPR000906] 0.4881914232442608 0.0618210765620323 0.9507053189195744 1.0 0.999730964490922 2 Q12955 1 +3'-5' exonuclease domain [IPR002562] 0.4847731510254974 0.0600218606331733 0.9521382238093392 1.0 1.0 2 Q01780 1 +Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333] 0.4841516469857168 0.0597034893841944 0.95239179256828 1.0 1.0 2 P00387 1 +Zinc finger, TFIIB-type [IPR013137] 0.480422622747059 0.0578486955746629 0.9538691496354532 1.0 1.0 2 P29083 1 +Peptidase M20, dimerisation domain [IPR011650] 0.4676817899316511 0.0521951611966051 0.9583731884857724 1.0 1.0 2 Q8IYS1 1 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.4499689247980265 0.04592088143652 0.9633733107524104 1.0 1.0 2 Q96CX2 1 +p21 activated kinase binding domain [IPR033923] 0.4425108763207075 0.0437649812142079 0.965091741267005 1.0 1.0 2 Q13153 1 +CRIB domain [IPR000095] 0.4425108763207075 0.0437649812142079 0.965091741267005 1.0 1.0 2 Q13153 1 +Arf GTPase activating protein [IPR001164] 0.4390926041019443 0.042863445634055 0.9658103881125712 1.0 1.0 2 Q8N6T3 1 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.4353635798632783 0.0419385785637804 0.9665476621919504 1.0 1.0 2 O60568 1 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.4344313238036226 0.041716614398414 0.9667246091159094 1.0 1.0 2 Q7Z4V5 1 +Exosome complex component, N-terminal domain [IPR025721] 0.4139216904910036 0.0376765339721669 0.9699455858869308 1.0 1.0 2 Q9Y3B2 1 +Myotubularin-like phosphatase domain [IPR010569] 0.4095711622125674 0.037004365279324 0.9704815251363456 1.0 1.0 2 Q9C0I1 1 +MIRO domain [IPR020860] 0.4070851460534609 0.0366457239166594 0.9707674855820212 1.0 1.0 2 Q8IXI1 1 +EF hand associated, type-1 [IPR013566] 0.4070851460534609 0.0366457239166594 0.9707674855820212 1.0 1.0 2 Q8IXI1 1 +EF hand associated, type-2 [IPR013567] 0.4070851460534609 0.0366457239166594 0.9707674855820212 1.0 1.0 2 Q8IXI1 1 +NECAP, PHear domain [IPR012466] 0.4067743940335704 0.0366021498148294 0.9708022293761572 1.0 1.0 2 Q9NVZ3 1 +CRK, C-terminal SH3 domain [IPR035458] 0.3993163455562572 0.035635872885903 0.9715727040512304 1.0 1.0 2 P46108 1 +CRK, N-terminal SH3 domain [IPR035457] 0.3993163455562572 0.035635872885903 0.9715727040512304 1.0 1.0 2 P46108 1 +Thioesterase domain [IPR006683] 0.3850217526414036 0.0341641274285969 0.9727462719967672 1.0 1.0 2 O00154 1 +Band 7 domain [IPR001107] 0.3171694106757965 0.0339769487103194 0.972895532350003 1.0 1.0 8 Q99623,O75955,Q9UJZ1,P27105 4 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.37228091982599 0.0331997539479972 0.9735152943366696 1.0 1.0 2 Q96S59 1 +CRA domain [IPR013144] 0.37228091982599 0.0331997539479972 0.9735152943366696 1.0 1.0 2 Q96S59 1 +Thioredoxin-like fold [IPR012336] 0.3707271597265491 0.0331009632419544 0.9735940746161976 1.0 1.0 2 Q6DKJ4 1 +rRNA-processing arch domain [IPR025696] 0.3645121193287854 0.0327416641065847 0.9738805985362408 1.0 1.0 2 Q15477 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.3645121193287854 0.0327416641065847 0.9738805985362408 1.0 1.0 2 Q15477 1 +NIPSNAP [IPR012577] 0.3620261031696811 0.0326129631007836 0.9739832322705272 1.0 1.0 2 O75323 1 +S1-like RNA binding domain [IPR025223] 0.3433809819763968 0.0318751449708919 0.9745716200050024 1.0 1.0 2 Q8N163 1 +LAIKA domain [IPR045353] 0.3433809819763968 0.0318751449708919 0.9745716200050024 1.0 1.0 2 Q8N163 1 +BURAN domain [IPR045354] 0.3433809819763968 0.0318751449708919 0.9745716200050024 1.0 1.0 2 Q8N163 1 +DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954] 0.3433809819763968 0.0318751449708919 0.9745716200050024 1.0 1.0 2 Q8N163 1 +Copine, C-terminal [IPR010734] 0.3380981976382997 0.0317264028292399 0.9746902390690012 1.0 1.0 2 Q99829 1 +Copine, C2B domain [IPR037768] 0.3380981976382997 0.0317264028292399 0.9746902390690012 1.0 1.0 2 Q99829 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.3192774381986643 0.0312111369124987 0.9751011582705056 1.0 1.0 4 Q8WVV9 1 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.270043505282798 0.0310055746931871 0.9752650938494238 1.0 1.0 2 Q9NVE7 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.3187189054726297 0.030609970386716 0.9755805906581724 1.0 1.0 4 Q9UBU9,Q9UN86,P61970 3 +Nuclear transport factor 2 domain [IPR002075] 0.3187189054726297 0.030609970386716 0.9755805906581724 1.0 1.0 4 Q9UBU9,Q9UN86,P61970 3 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.3058750388560843 0.0200438879359619 0.984008362077864 1.0 1.0 3 Q9BUJ2,Q1KMD3 2 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.3061110469597474 0.0181663572065778 0.9855061412653972 1.0 1.0 4 P10586 1 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.2964497600373406 0.0093440076578642 0.9925446690420106 1.0 1.0 12 Q9Y696,P78417 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1944518f97558481c6bef73f60ba36ac62b62fad --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bms1/Tsr1-type G domain [IPR030387]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophilin subfamily 1/2, SPRY/PRY domain [IPR037958]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CCZ1/INTU, second Longin domain [IPR043988]", "CCZ1/INTU/HPS4, third Longin domain [IPR043989]", "CCZ1/INTU/HSP4, first Longin domain [IPR043987]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHAT domain [IPR024983]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XIX myosin, motor domain [IPR036035]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper homeostasis CutC domain [IPR023648]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase 3-like, TOPRIM domain [IPR034144]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IA, DNA-binding domain [IPR003602]", "DNA topoisomerase, type IA, central [IPR013497]", "DNA topoisomerase, type IA, domain 2 [IPR003601]", "DNA topoisomerase, type IA, zn finger [IPR013498]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF625 [IPR006887]", "Domain of unknown function DUF775 [IPR008493]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM21/CAPZIP domain [IPR029341]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM7, LYR domain [IPR045298]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MYND-like zinc finger [IPR031615]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylguanine DNA methyltransferase, ribonuclease-like domain [IPR008332]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotubularin-like phosphatase domain [IPR010569]", "Myotubularin-related 12-like C-terminal domain [IPR022587]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NACHT nucleoside triphosphatase [IPR007111]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, N-terminal [IPR002871]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Patatin-like phospholipase domain-containing protein 2 [IPR033903]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxin 13, N-terminal [IPR007223]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RING1 , RING finger, HC subclass [IPR042741]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPK118-like, kinase domain [IPR035053]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S6 kinase delta-1, PX domain [IPR042132]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX8/Mvp1, PX domain [IPR035704]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine proteases, trypsin domain [IPR001254]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm4 [IPR034101]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 8/Mvp1, BAR domain [IPR045734]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 2, SAM domain [IPR037610]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TMEM62, metallophosphatase domain [IPR041871]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Lyn, SH2 domain [IPR035852]", "Tyrosine-protein kinase Lyn, SH3 domain [IPR035748]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 11, C-terminal [IPR024763]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain [IPR030383]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, SWIM-type [IPR007527]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "APMAP", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL8A", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2L", "AUP1", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCS1L", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BRD2", "BRD4", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUD23", "BZW1", "BZW2", "C11orf58", "C1orf35", "C2CD5", "C3orf58", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALM3", "CALU", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CASK", "CBL", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK6", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT2", "CNOT3", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COMMD2", "COMMD4", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDHD2", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DIDO1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FANCA", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR180", "GPR89B", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF3C1", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INA", "INF2", "INTS14", "INTS3", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "IVD", "IWS1", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRSAM1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MAN2A1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MEPCE", "METAP1", "METAP2", "METTL13", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MGMT", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX13", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCL1", "RCN1", "RCN2", "RDX", "RECQL", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RING1", "RIOK1", "RIOK2", "RIPK1", "RMND1", "RNASEH2A", "RNF40", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS9", "RPSA", "RRBP1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTCA", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF4", "SCCPDH", "SCLY", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD1A", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC38A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPEN", "SPHK2", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6L", "TAGLN2", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM62", "TMEM97", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSR1", "TST", "TTC28", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXN2", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "UHRF1BP1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VKORC1L1", "VPS11", "VPS13A", "VPS18", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC2A", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YBX1", "YIPF4", "YKT6", "YME1L1", "YOD1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF207", "ZNF281", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZSWIM8", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ACBD3", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACTN1", "ACTN4", "AFG3L2", "AGK", "AGPAT2", "AGPAT5", "AKAP8", "AKT2", "ANK3", "ANKLE2", "ARFGAP1", "ARMCX3", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "AUP1", "BAG3", "BAG4", "BAG5", "BSG", "CALU", "CCAR2", "CD2BP2", "CD47", "CDKAL1", "CETN2", "CHERP", "CIRBP", "CLCN7", "CLIC4", "CNNM3", "CNOT2", "COPS6", "CPNE1", "CPSF6", "CPT2", "CRK", "CRKL", "CSE1L", "CTDSPL2", "CYB5B", "CYB5D2", "CYB5R3", "DCTN1", "DDHD2", "DKC1", "EBP", "EFCAB14", "EIF3F", "ELMO2", "EMD", "ERAP1", "ERGIC3", "ETFDH", "EWSR1", "EXOSC1", "EXOSC10", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP7", "FLOT1", "FOXRED1", "FUCA2", "FUS", "G3BP2", "GALNT4", "GFPT1", "GNPAT", "GRB2", "GRWD1", "GSK3A", "GSTO1", "GTF2E1", "HADH", "HDGFL2", "HLA-C", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPLL", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "ILF2", "ILF3", "INA", "IPO8", "ITM2B", "KCTD12", "KHSRP", "KMT2A", "LBR", "LETM1", "LMNB2", "LNPEP", "LPCAT1", "LYN", "M6PR", "MAPRE2", "MCM2", "MCM3", "MCM6", "MFN1", "MICU2", "MOSPD2", "MPP2", "MPP5", "MPST", "MRPL45", "MSH2", "MSMO1", "MTMR12", "MTX1", "MTX2", "MYL6B", "NCLN", "NECAP2", "NEFL", "NEFM", "NENF", "NIP7", "NIPSNAP2", "NISCH", "NONO", "NPEPPS", "NPTN", "NSD2", "NUCB1", "NUCB2", "NUTF2", "NXF1", "NXN", "OCIAD1", "OS9", "P3H1", "P4HA1", "PACSIN3", "PAK1", "PANK4", "PCYOX1", "PDCD6", "PGRMC1", "PGRMC2", "PHB2", "PLD3", "PLOD3", "PM20D2", "PMPCA", "PPAT", "PPIL4", "PSMD14", "PSME3", "PTGR1", "PTPN11", "PTPRF", "PUF60", "RABGAP1", "RANBP9", "RAPGEF2", "RBM10", "RBM14", "RBM3", "RBM39", "RBM4", "RBMX", "RBPMS", "RCN2", "RHOT2", "RIPK1", "RPRD1B", "RPRD2", "RPS6KA1", "RPS6KC1", "RTN2", "RTN3", "RTN4", "SCAF4", "SEC31A", "SEL1L", "SETD1A", "SFPQ", "SKIV2L", "SKP1", "SLC16A1", "SLC25A24", "SLC2A1", "SLIRP", "SNX2", "SNX5", "SNX6", "SPNS1", "SPTAN1", "SRSF1", "SRSF3", "SRSF9", "STAT1", "STAT3", "STOM", "STOML2", "STRBP", "STX10", "STX12", "STX4", "SUN2", "SUPT6H", "SYAP1", "SYNCRIP", "TAF15", "TBC1D15", "TBC1D9B", "TBCB", "TIAL1", "TIMM10", "TIMM8B", "TLCD1", "TMED10", "TMED2", "TMED7", "TMED9", "TMPO", "TRA2B", "TRAM1", "TRIM13", "TRMT2A", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "U2AF2", "U2SURP", "UBLCP1", "UNC119B", "UQCRC2", "VAPA", "VIM", "ZADH2", "ZCCHC3", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cebd2625a48b1bd59d52168d8236a1cb2344bd59 --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bd5c0b19cfaa612ce3c66f4108442fc90e65dd24 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:164eb41558463c3ea12c3f6019f397001e25c750e418bcdc4d9aeadb17c885b1 +size 186768 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a8654a7da47fa3a824d9badafd1922e076d5a445 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47bdc15088c4d34c0ac9c679dda8817dd7df49211ca18ca3b7f0047f3ff437a8 +size 181363 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..69bed8d6a4c537d6192e8795a855d5717a415a49 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Proteasome, subunit alpha/beta [IPR001353]", "3": "Tubulin [IPR000217]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5342f7d973435ee6ce295a6c2414ae847cc3654b --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c8aa42096cc74fd3af186ab163055f8e53c7639b3c68963fa265fc749bb2152 +size 136725 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..60e92385869da983463bf96138be4fb42a2026e8 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:994eb2858aa75fb76f8148c562b824f2f15465ca7abe770663f2e515bba10d1b +size 138743 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b959ed174688dae3be80404f0ba248e4815991cf --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:638f6f9800f768b2311ec23eee34c30f44cd32e43ad5725727157ffe4c60baf0 +size 142178 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..0adb802cd00494475c66f120c01c04aad2bfa414 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be882bd85c6b436a061af749e08e63a9650d24243c270fb95e9c42932326aab2 +size 124560 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..506a7f6e37628b5c0b0fa6282a1c41c8025e810f --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:724899e5549072846140e0d5f0ba0e256b78877c30b8c809344e96ab34852d5a +size 246398 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0b89bf70790880cdff4c018ca76ee8838bf8060d --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 10 13 2.4733044212115542 0.013387005554857 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.002793958835087 1.0 0.179062604831997 0.0011814468070448 0.00223229240551 +Proteasome B-type subunit [IPR023333] 5 7 2.4220238524198625 0.0154343374348433 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0020591533048899 0.0432957136582515 0.0849171013653387 0.0186627473263165 2.8311070051942505e-05 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 3 6 2.3019189181843065 0.0213397451280803 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.0014043590152869 1.0 0.0758460972151271 0.0007102815399137 0.0003286021100258 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dc5d9b504654fb0abcbb9a41c0fd4b90e9b0da12 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 2512, + "title": "Average number of proteins per term", + "value": 1.293391719745223 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7e59ae744a03d9e17fef2f9d44fb2825c2d89bdf --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..00b5ce21decf2ae0216cc2d17380f7b6c5c5c80e --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,145 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier protein [IPR002067] 0.7168501782133493 2.4733044212115542 0.013387005554857 0.999999999999998 0.2935104873258359 13 P12236,Q96H78,Q9BQT8,P12235,Q6NUK1,Q9HC21,Q9UJS0,P16260,P05141,O43808 10 +Proteasome B-type subunit [IPR023333] 0.8422843905158065 2.4220238524198625 0.0154343374348433 1.0 0.2935104873258359 7 P49721,P28070,P20618,P28074,P28072 5 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.843332381192831 2.3019189181843065 0.0213397451280803 1.0 0.2935104873258359 6 Q9NZ08,Q9UIQ6,P55786 3 +Aminopeptidase N-type [IPR034016] 0.8777788596785823 1.9906485767592448 0.0465195357999814 1.0 0.2968999633897339 4 Q9NZ08,P55786 2 +Eukaryotic porin/Tom40 [IPR027246] 0.86691542288557 1.9471061963359984 0.0515220043018735 1.0 0.3002875754974676 4 Q9Y277,P21796,P45880 3 +P-type ATPase [IPR001757] 0.7828926905132111 1.880923714687644 0.0599822967609045 1.0 0.308836744283289 5 Q9HD20,P05023,P98194,P16615 4 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9791731426795138 1.8296250976059492 0.0673060181744917 1.0 0.3194406939600389 3 Q5VW38,Q8NBN3 2 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7617418351477303 1.7886223309397675 0.0736756590114544 1.0 0.3277983947464282 5 Q9BVK6,Q9Y3B3,Q15363,P49755 4 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9664283493938438 1.7825411912754807 0.0746610202450503 1.0 0.3284561871375947 3 Q9H3G5,P10619 2 +Proteasome, subunit alpha/beta [IPR001353] 0.5853815471526197 1.7693835658533037 0.0768298862894365 1.0 0.3316094061152312 14 P49721,P28070,P20618,P28074,P28072,Q99436 6 +Tetraspanin/Peripherin [IPR018499] 0.9459123406900792 1.706464136438597 0.0879216981132899 1.0 0.3445542990024718 3 O43657,O60637 2 +TB2/DP1/HVA22-related protein [IPR004345] 0.786380597014923 1.6192230290324388 0.1053992847796789 1.0 0.3723811580401597 4 Q9BRK0,Q00765,Q9H6H4 3 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.9128247348089058 1.583135866466814 0.1133905002684168 1.0 0.3814045604927467 3 Q9NPH0 1 +Porin, eukaryotic type [IPR001925] 0.9079888094497872 1.565056283187722 0.1175697128585482 1.0 0.3862478790559533 3 P45880,P21796 2 +Sulfotransferase [IPR005331] 0.9045694746658356 1.552265735034885 0.1205986530694445 1.0 0.3909387448129637 3 Q8NCH0,Q7LGA3 2 +Mpv17/PMP22 [IPR007248] 0.9018084933432222 1.5419338511637577 0.1230896689114711 1.0 0.3926098138329208 3 Q567V2 1 +Mini-chromosome maintenance protein [IPR031327] 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.4052306105035415 6 Q14566,P25205,P49736 3 +Tubulin [IPR000217] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.4052306105035415 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Beta tubulin [IPR002453] 0.646147672788906 1.498761826334304 0.1339354310326141 1.0 0.4094720968614884 7 P68371,Q13509,P04350,Q9BVA1 4 +Cytochrome P450 [IPR001128] 0.8778304005128176 1.4520813070181855 0.1464789989106387 1.0 0.4293526782538209 3 Q16850 1 +Nonaspanin (TM9SF) [IPR004240] 0.8765930991607004 1.447440045140819 0.1477737169133637 1.0 0.4311353970805687 3 Q9HD45,Q99805 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.875038856077089 1.441609418104096 0.1494125900346872 1.0 0.4336165979008111 3 Q99733,P55209 2 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.8737954616101975 1.436944555010522 0.1507337485082409 1.0 0.4341873721585979 3 P35610,Q96N66 2 +Syntaxin [IPR045242] 0.6012600099328306 1.3762068572052737 0.1687575997248349 1.0 0.4577959940699626 8 O60499 1 +ER lumen protein retaining receptor [IPR000133] 0.9841516469857045 1.3471589276506368 0.1779290528175372 1.0 0.4685092040646263 2 P24390 1 +Palmitoyl protein thioesterase [IPR002472] 0.982908638906152 1.3425284646957636 0.1794247073711568 1.0 0.4709664210202151 2 P50897 1 +Tetraspanin, animals [IPR000301] 0.9798011187072696 1.33095599925343 0.1832034894203955 1.0 0.4768986170197239 2 O60637 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8451973888716194 1.3296112217276927 0.1836463988641123 1.0 0.4775086290295898 3 P28074,P28072 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.8423997513211051 1.3191123580442865 0.1871315522812606 1.0 0.4798291197398194 3 O60831,Q9UI14 2 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9742075823492828 1.3101399201808004 0.1901485058376946 1.0 0.482477824913423 2 O60830 1 +CD36 family [IPR002159] 0.9689247980111853 1.29049906042445 0.1968774378490632 1.0 0.4911182958062033 2 Q8WTV0 1 +TAF15/EWS/TLS family [IPR034870] 0.8333851414361093 1.2852928667398138 0.1986899619318676 1.0 0.4931908936490626 3 Q92804,P35637 2 +Mitochondrial carrier UCP-like [IPR002030] 0.9670602858918582 1.283571740642857 0.19929184285238 1.0 0.4937091807151662 2 Q9UBX3 1 +Nucleobindin [IPR040250] 0.9596022374145384 1.255889679048881 0.2091559710583954 1.0 0.5066536155242907 2 P80303 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8238945755225329 1.2497129765507713 0.211404415284345 1.0 0.5086665624466233 3 Q9Y282 1 +Peroxisomal biogenesis factor 11 [IPR008733] 0.9487259167184552 1.2156081817704707 0.2241342159165973 1.0 0.526652339369134 2 Q96HA9 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.8078955548647815 1.1898256210632183 0.2341149372288562 1.0 0.5382815540252711 3 O43823,Q5BKZ1 2 +Prenylcysteine oxidase [IPR017046] 0.935985083903041 1.1685791392323468 0.2425732370467184 1.0 0.5459652446141094 2 Q9UHG3 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.7929748212620389 1.134128689358328 0.2567405709496482 1.0 0.5609089641339416 3 P12236,P12235 2 +AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752] 0.9251087632069523 1.1285923138679708 0.2590698545570111 1.0 0.5618485766816578 2 O00400 1 +Integral membrane protein 2 [IPR040145] 0.9123679303915412 1.0819714472087163 0.279265215440386 1.0 0.5787662475378877 2 Q9Y287 1 +Vang-like protein [IPR009539] 0.9117464263517644 1.0797040069891517 0.2802740090044557 1.0 0.5787811311319534 2 Q9ULK5 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.9086389061528816 1.0683768682089103 0.2853505470683368 1.0 0.5837138226674773 2 Q15070 1 +Glycoside hydrolase, family 29 [IPR000933] 0.906774394033561 1.0615888152566837 0.2884223935068983 1.0 0.5871288918065873 2 Q9BTY2 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.906774394033561 1.0615888152566837 0.2884223935068983 1.0 0.5871288918065873 2 Q9BTY2 1 +Carbohydrate sulfotransferase 8-10 [IPR018011] 0.904288377874445 1.0525479641941615 0.2925482167375151 1.0 0.590550946410351 2 Q8NCH0 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9011808576755748 1.0412632529363623 0.2977533864318973 1.0 0.5957965835041876 2 Q93050 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9011808576755748 1.0412632529363623 0.2977533864318973 1.0 0.5957965835041876 2 Q93050 1 +Type 1 protein exporter [IPR039421] 0.5950048173740222 1.041180661323509 0.2977917092388764 1.0 0.5957965835041876 5 O75027,P08183 2 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.897451833436915 1.0277464482562224 0.3040691126066153 1.0 0.5989891997471284 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.897451833436915 1.0277464482562224 0.3040691126066153 1.0 0.5989891997471284 2 O15254 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.8875077688004895 0.991842708123384 0.3212742604084293 1.0 0.6146541828986859 2 Q96KA5 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.8875077688004895 0.991842708123384 0.3212742604084293 1.0 0.6146541828986859 2 Q96KA5 1 +Tricarboxylate/iron carrier [IPR004686] 0.7541821909691702 0.9904643178231672 0.3219472215918362 1.0 0.6150048826149753 3 Q96NB2 1 +Ribonucleotide reductase small subunit family [IPR000358] 0.8660658794282167 0.915217093567991 0.3600776726613151 1.0 0.6554457345834952 2 Q7LG56 1 +Ribonucleotide reductase small subunit [IPR033909] 0.8660658794282167 0.915217093567991 0.3600776726613151 1.0 0.6554457345834952 2 Q7LG56 1 +CDP-alcohol phosphatidyltransferase [IPR000462] 0.8620261031696709 0.9009167637933329 0.3676325773299935 1.0 0.6618026306399936 2 O14735 1 +Ribosomal protein S6 kinase II [IPR016239] 0.8564325668116795 0.8811951047550342 0.3782122283909155 1.0 0.6706544105899636 2 Q15418 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.8523927905531207 0.8670110591486583 0.3859359502551789 1.0 0.6741801857030664 2 Q14739 1 +Stomatin/HflK/HflC family [IPR001972] 0.8520820385332509 0.8659221047815617 0.3865328801544083 1.0 0.6742181992631014 2 P27105 1 +Glutathione Transferase family [IPR040079] 0.4599180353960328 0.864524721195159 0.3872997060257386 1.0 0.6742181992631014 11 Q9Y696,O75431,Q9H7Z7,Q13505 4 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8440024860161601 0.8377199641222485 0.4021879982907463 1.0 0.685411296951394 2 Q9NVI7 1 +Yif1 family [IPR005578] 0.8430702299564785 0.8344799710513431 0.4040105692677844 1.0 0.6880505423733387 2 Q5BJH7 1 +Chloride channel, voltage gated [IPR001807] 0.8415164698570392 0.8290866682633338 0.4070553670460555 1.0 0.6899283890187974 2 P51798 1 +HnRNP R/Q splicing factor [IPR006535] 0.8368551895587333 0.8129579505255952 0.4162421672364691 1.0 0.6952129814481453 2 O43390 1 +Basigin-like [IPR043204] 0.8206960845245466 0.7576787059547836 0.4486433497579938 1.0 0.7244235034886891 2 Q9Y639 1 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.8178993163455408 0.7482176900968175 0.4543288624110628 1.0 0.7273894852623262 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.8178993163455408 0.7482176900968175 0.4543288624110628 1.0 0.7273894852623262 2 Q9BUR5 1 +Cytochrome c oxidase subunit VII [IPR039297] 0.8144810441267694 0.7366995396166492 0.4613050868779371 1.0 0.7324894931968255 2 P14406 1 +Cytochrome c oxidase subunit VIIa, metazoa [IPR003177] 0.8144810441267694 0.7366995396166492 0.4613050868779371 1.0 0.7324894931968255 2 P14406 1 +Bcl2-like [IPR002475] 0.6823127137084167 0.7326136502230164 0.4637941032406805 1.0 0.733207352132315 3 Q07820,Q9BXK5 2 +Bcl-2 family [IPR026298] 0.6823127137084167 0.7326136502230164 0.4637941032406805 1.0 0.733207352132315 3 Q07820,Q9BXK5 2 +Graves disease carrier protein [IPR002167] 0.8067122436295662 0.7107141979676873 0.4772613596382182 1.0 0.747419163296261 2 P16260 1 +Bax inhibitor 1-related [IPR006214] 0.8008079552516862 0.6911519232567938 0.4894700730429266 1.0 0.7585125376211177 2 Q9H3K2 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.7967681789931663 0.6778642529468616 0.4978577670888873 1.0 0.7658412191838854 2 P11279 1 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.7952144188937018 0.6727752050775152 0.5010903143306771 1.0 0.7670559839114325 2 P23786 1 +Anoctamin [IPR007632] 0.7883778744561871 0.650530260376084 0.5153497617590546 1.0 0.7765798449542562 2 Q4KMQ2 1 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.7862026103169648 0.6435037905647816 0.519897255954215 1.0 0.7796906907205899 2 Q9P035 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.7843380981976418 0.6375013868935476 0.5237983068597873 1.0 0.7817790862503374 2 Q9NR31 1 +Major facilitator superfamily [IPR011701] 0.4971966832128916 0.6103090584982472 0.5416570974431201 1.0 0.7917252485483924 5 P53985,Q96ES6,Q9H2V7 3 +Prenyltransferase subunit beta [IPR045089] 0.7666252330639938 0.5814602188699567 0.5609303219860713 1.0 0.8047126005538654 2 P49356 1 +Phosphatidyl serine synthase [IPR004277] 0.7663144810441104 0.5804936109023419 0.5615817940630479 1.0 0.8047310135119088 2 Q9BVG9 1 +Methylthiotransferase [IPR005839] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.8192687217238434 2 Q5VV42 1 +Protein arginine N-methyltransferase [IPR025799] 0.4761649994902031 0.5231141447316794 0.6008948228195958 1.0 0.8302793151390675 5 Q6P2P2 1 +OCIA domain-containing protein 1/2 [IPR040187] 0.7402113113735013 0.501537933104526 0.6159925882891271 1.0 0.8395948897353701 2 Q9NX40 1 +Torsin 1/2 [IPR017378] 0.7377252952144243 0.4942628536365778 0.6211205554942532 1.0 0.8441431397009513 2 O14657 1 +Actin family [IPR004000] 0.460031104199065 0.4584682371096883 0.6466160771696798 1.0 0.8530112910183356 5 O96019,Q9NZ32,P61160,P61163 4 +SUN domain-containing protein 1-5 [IPR045119] 0.7125543816034565 0.4232475545050143 0.672114654209935 1.0 0.8661314997309152 2 Q9UH99 1 +Dephospho-CoA kinase [IPR001977] 0.71037911746427 0.41734817567756 0.676423755511234 1.0 0.8676538622854384 2 Q13057 1 +Plakophilin/Delta catenin [IPR028435] 0.7038533250466021 0.3998894968397594 0.6892379086066351 1.0 0.8757539840262354 2 O00192 1 +Microtubule-associated protein RP/EB [IPR027328] 0.7026103169670559 0.3966053688864076 0.6916584928013907 1.0 0.876380399833261 2 Q15555 1 +Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100] 0.6998135487880739 0.3892651930252456 0.6970799817048401 1.0 0.8781463265576013 2 P00390 1 +Peroxysomal long chain fatty acyl transporter [IPR005283] 0.6898694841516484 0.3637284176509114 0.7160608205750305 1.0 0.8873925906682174 2 P33897 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.6730888750776961 0.322701269845695 0.7469214903596411 1.0 0.9000887491944454 2 Q9Y5Y2 1 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.6730888750776961 0.322701269845695 0.7469214903596411 1.0 0.9000887491944454 2 Q9Y5Y2 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.6721566190180317 0.320500631895138 0.7485888514254746 1.0 0.9000887491944454 2 Q9P0I2 1 +Flotillin family [IPR027705] 0.6706028589185911 0.316851694611429 0.7513561369106212 1.0 0.9000887491944454 2 O75955 1 +Synaptobrevin [IPR001388] 0.6569297700435139 0.2857704650024315 0.7750539306942765 1.0 0.9080855755149358 2 P51809 1 +Proteasome activator PA28 [IPR009077] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.910973504107324 3 P61289 1 +Transcription factor STAT [IPR001217] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.9124874944514844 2 P40763 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.6500932256059753 0.2709372929551426 0.78643926173864 1.0 0.9124874944514844 2 P05026 1 +CPSF6/7 family [IPR034772] 0.6472964574269661 0.2650077474767155 0.7910034935137202 1.0 0.9144044066757778 2 Q16630 1 +Copper chaperone SCO1/SenC [IPR003782] 0.6367308887507822 0.2433437259515302 0.8077391337828559 1.0 0.919782730762708 2 O75880 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.6367308887507822 0.2433437259515302 0.8077391337828559 1.0 0.919782730762708 2 O75880 1 +Mitofusin family [IPR027094] 0.6357986326911085 0.2414886085901738 0.8091764443059013 1.0 0.9201680525560996 2 Q8IWA4 1 +Oxysterol-binding protein [IPR000648] 0.4284825870646682 0.2388936149154728 0.8111880767968862 1.0 0.9207882733455844 4 Q9BXB4,P22059,Q9BZF1 3 +Importin beta family [IPR040122] 0.391671110289905 0.2153482391226509 0.8294958223795437 1.0 0.9253798070885982 5 Q8TEX9,O00410 2 +Not2/Not3/Not5 [IPR040168] 0.5929148539465618 0.1662546544089056 0.8679565498720567 1.0 0.9325521185964954 2 Q9NZN8 1 +Molecular chaperone regulator BAG [IPR039773] 0.4724898974199626 0.1577879641935169 0.8746238830278774 1.0 0.9357134557776952 3 Q9UL15,O95429 2 +Prohibitin [IPR000163] 0.5494095711622257 0.1100734299869656 0.9123511398889737 1.0 0.9529422301044084 2 Q99623 1 +S-phase kinase-associated protein 1-like [IPR001232] 0.5388440024860264 0.099347661625252 0.920862237061054 1.0 0.9551360045095896 2 P63208 1 +Sorting nexin-5/6/32 [IPR014637] 0.5351149782473723 0.0958188790940697 0.9236644230013532 1.0 0.9568020744657316 2 Q9Y5X3 1 +Clathrin adaptor, mu subunit [IPR001392] 0.4261734535281377 0.0919069537222774 0.926771966577046 1.0 0.9580457531035144 3 Q9BXS5,Q96CW1 2 +UBAP2/protein lingerer [IPR022166] 0.5242386575512883 0.0862656746717573 0.9312552243696106 1.0 0.960922781320241 2 Q14157 1 +Peptidase, FtsH [IPR005936] 0.5180236171535259 0.0812851277443105 0.935215201190362 1.0 0.9636015526620958 2 Q9Y4W6 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.4128069630090182 0.0774951306849651 0.9382296647771236 1.0 0.965519425612509 3 Q9HCS7,Q9BZJ0 2 +Ribosomal protein L22/L17 [IPR001063] 0.5093225605966585 0.0748713273299741 0.9403170899824596 1.0 0.9667912905895448 2 P18621 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.5080795525171062 0.0740066951429667 0.9410050579185656 1.0 0.9667912905895448 2 P07910 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.5055935363579973 0.0723151913808026 0.9423510753751412 1.0 0.9677783734024344 2 Q9P0L0 1 +NADH:cytochrome b5 reductase-like [IPR001834] 0.4841516469857168 0.0597034893841944 0.95239179256828 1.0 0.976144670187887 2 P00387 1 +Translation Initiation factor eIF- 4e [IPR001040] 0.481354878806728 0.058303567505583 0.953506825892736 1.0 0.976812145299939 2 P06730 1 +Peptidase M20 [IPR002933] 0.4676817899316511 0.0521951611966051 0.9583731884857724 1.0 0.9806246230045866 2 Q8IYS1 1 +KH domain-containing BBP-like [IPR045071] 0.3792086294070886 0.0494999184774843 0.9605209021672548 1.0 0.9820221840635508 3 Q07666 1 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.4518334369173572 0.0465023263865778 0.962909879905742 1.0 0.983332164544265 2 Q9Y3E5 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.3736400373018427 0.0458980348061649 0.9633915205257488 1.0 0.983332164544265 3 Q9Y3C6,Q96BP3 2 +Profilin1/2/3, vertebrate [IPR005454] 0.4449968924798187 0.0444541761679887 0.9645423779606166 1.0 0.983332164544265 2 P35080 1 +Profilin [IPR005455] 0.4449968924798187 0.0444541761679887 0.9645423779606166 1.0 0.983332164544265 2 P35080 1 +Macrophage migration inhibitory factor [IPR001398] 0.4322560596644014 0.0412126926328908 0.9671263350125628 1.0 0.985166810037128 2 P14174 1 +Ribosomal protein L14P [IPR000218] 0.4210689869484328 0.0389125600684594 0.9689601026675534 1.0 0.9860926367051168 2 Q6P1L8 1 +ClpA/B family [IPR001270] 0.4192044748291046 0.0385735957203484 0.9692303541828626 1.0 0.9860926367051168 2 Q9H078 1 +Myotubularin family [IPR030564] 0.4095711622125674 0.037004365279324 0.9704815251363456 1.0 0.9860926367051168 2 Q9C0I1 1 +Mitochondrial Rho GTPase [IPR021181] 0.4070851460534609 0.0366457239166594 0.9707674855820212 1.0 0.9860926367051168 2 Q8IXI1 1 +Calponin/LIMCH1 [IPR001997] 0.3812927284027437 0.0338515005209795 0.9729955679776264 1.0 0.9860926367051168 2 Q99439 1 +Ribosomal protein L37/S30 [IPR010793] 0.3766314481044265 0.033496990306526 0.9732782658741403 1.0 0.9860926367051168 2 Q9NP92 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.3729024238657705 0.0332403299619402 0.973482937220725 1.0 0.9860926367051168 2 Q29RF7 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.3645121193287854 0.0327416641065847 0.9738805985362408 1.0 0.9860926367051168 2 Q15477 1 +Prefoldin alpha-like [IPR004127] 0.3642013673089046 0.0327251274361686 0.9738937858234344 1.0 0.9860926367051168 2 P61758 1 +Cell cycle and apoptosis regulator protein [IPR025224] 0.3433809819763968 0.0318751449708919 0.9745716200050024 1.0 0.9860926367051168 2 Q8N163 1 +Copine [IPR045052] 0.3380981976382997 0.0317264028292399 0.9746902390690012 1.0 0.9860926367051168 2 Q99829 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.3144810441267987 0.0312865039089204 0.975041053460682 1.0 0.9860926367051168 2 P36404 1 +HnRNP-L/PTB [IPR006536] 0.3192774381986643 0.0312111369124987 0.9751011582705056 1.0 0.9860926367051168 4 Q8WVV9 1 +Hydantoinase/dihydropyrimidinase [IPR011778] 0.3232825613926034 0.0240691502938424 0.9807974506897316 1.0 0.9906566932579836 3 Q16555,Q9BPU6 2 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.2838835461764631 0.0223050706972657 0.9822046040581672 1.0 0.9916792465410436 18 Q06136,Q3SXM5,Q53GQ0,Q8NBN7 4 +Torsin [IPR010448] 0.2920093931047234 0.017743392758585 0.9858435636726186 1.0 0.993755630796797 3 O14657 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c549c1b7c17df90ed3767f78b7be324de7a21b83 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S10, mitochondrial [IPR040055]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette sub-family D member 1 [IPR031237]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl carrier protein (ACP) [IPR003231]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase [IPR011408]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-10 [IPR031291]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit [IPR006111]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK2-associated and cullin domain-containing protein 1 [IPR042652]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGG triplet repeat-binding protein 1 [IPR033375]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein H [IPR040034]", "Centromere protein I [IPR012485]", "Centromere protein P [IPR027801]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Copper homeostasis protein CutC [IPR005627]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome P450, cholesterol 7-alpha-monooxygenase-type [IPR024204]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX16 [IPR020164]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IA [IPR000380]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit RPB6 [IPR028363]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Decaprenyl diphosphate synthase-like [IPR001441]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrodolichyl diphosphate synthase complex subunit Nus1 [IPR038887]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Disks large-associated protein 4 [IPR030527]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase KCMF1 [IPR039858]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 10 [IPR029615]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Emopamil-binding protein [IPR007905]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Essential MCU regulator, mitochondrial [IPR018782]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FUN14 [IPR007014]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "Galactokinase [IPR000705]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 4 [IPR000715]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "ISC system FeS cluster assembly, IscU scaffold [IPR011339]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosomal-associated transmembrane protein 4/5 [IPR004687]", "Lysosomal-associated transmembrane protein, 4A/5 [IPR018396]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannosyltransferase ALG2 [IPR027054]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type D protein [IPR019362]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase kinase kinase kinase [IPR021160]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 12 [IPR030576]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "N6-adenosine-methyltransferase non-catalytic subunit METTL14-like [IPR045123]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5 [IPR019342]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear pore protein POM121 [IPR026090]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "OPI10 family [IPR031318]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic antigen Ma2 [IPR026525]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S1A, chymotrypsin family [IPR001314]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin 13 [IPR035463]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 11C, metazoa [IPR026510]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxisome membrane protein, Pex16 [IPR013919]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRICK1 [IPR033378]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA methyltransferase [IPR003750]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase, subunit omega/Rpo6/RPB6 [IPR006110]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Rad9 [IPR026584]", "Rad9/Ddc1 [IPR007268]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinol-binding protein 1 [IPR031264]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L55, mitochondrial [IPR018615]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27 [IPR000592]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase Rio1 [IPR017407]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-8/Mvp1 [IPR028662]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, cytochrome b556 subunit [IPR014314]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit [IPR000701]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Sulphide quinone-reductase [IPR015904]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Syntaxin-17 [IPR028676]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TIP41-like protein [IPR007303]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "TSC-22 / Dip / Bun [IPR000580]", "Tankyrase 1-binding protein-like [IPR040006]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin [IPR005746]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "Torsin-3A [IPR030552]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcriptional regulator TACO1-like [IPR002876]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 11 [IPR026120]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 223 [IPR026100]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Type-1 angiotensin II receptor-associated protein [IPR009436]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase [IPR033895]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1-binding protein 1-like [IPR026728]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "UbiE/COQ5 methyltransferase [IPR004033]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTU1/2/3 [IPR039138]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family UPF0729 [IPR026776]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar fusion protein Ccz1 [IPR013176]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 11 [IPR016528]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "Xyloside xylosyltransferase 1 [IPR042465]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter 9 [IPR040177]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA export factor GLE1-like [IPR012476]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AK1", "AK2", "AK3", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH16A1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BASP1", "BAX", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRAT1", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C11orf58", "C12orf43", "C14orf2", "C16orf58", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CAST", "CBL", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC37", "CDC42", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPH", "CENPI", "CENPP", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHERP", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWF19L1", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EHD1", "EHD4", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS7", "INTS9", "IPO4", "IPO5", "IRGQ", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KCMF1", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LLPH", "LMF2", "LNPEP", "LNPK", "LONP1", "LPCAT3", "LRPAP1", "LRPPRC", "LRRC47", "LRRFIP1", "LSM12", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL14", "METTL3", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAB1", "NDUFAF3", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS7", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFCD", "NELFE", "NES", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NRM", "NSA2", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUS1", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCIAD2", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PELO", "PES1", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA2", "PNPT1", "POFUT1", "POLA1", "POLA2", "POLD1", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM6", "RBM8A", "RBP1", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "REXO4", "RFC1", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RNASEH2A", "RNASET2", "RNF40", "RNPEP", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCLY", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMG5", "SMIM12", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SPAG9", "SPART", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPNS1", "SPOUT1", "SPR", "SPTBN1", "SQLE", "SQOR", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAT1", "STAT3", "STIM2", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TECR", "TEDC1", "TEFM", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TLE3", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", 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0000000000000000000000000000000000000000..4c2bc48c26813868cf1bdb7ace8ee20d0ef5e284 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:670a93bf6a1a03e19a9fe9c29337d89fadb9c019e712328cf42068631347f6d3 +size 128931 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..97a3f2f288ecda715cf89e4cd6de0ee69b9fd7b2 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d54ee1118df2d5b85982500eb8b92419840036d7e8f6a6590bd729cdb72079c9 +size 139540 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a41df86c50b77134f0e27633d9f586124d9811a4 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:919a635f8a08bdbf433d1e962efe73345d13c4a8da5c12ef1f9dbc6b1830199a +size 112699 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..42646c54d412dbb4dd37303c490df1388b40c1da --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 17 23 3.255855026330845 0.0011305145969235 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.506811130714988e-05 0.1706778675257841 0.0532804729840314 2.679082783141478e-06 1.279082532544537e-07 +Peptidase M4/M1, CTD superfamily [IPR027268] 3 6 2.3019189181843065 0.0213397451280803 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0020591533048899 1.0 0.0849171013653387 0.0010464818333657 0.0005688349419973 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 3 6 2.3019189181843065 0.0213397451280803 2.111650485436894 5.548543689320389 1.4203309343737989 0.1835434124596617 1.027373025804284 0.6683357213562342 0.9844971330203006 0.2264468231852968 0.0020591533048899 1.0 0.0849171013653387 0.0010464818333657 0.0005688349419973 +FAD/NAD(P)-binding domain superfamily [IPR036188] 7 21 2.2264163579000367 0.0259863057977605 5.128640776699029 19.483009708737864 1.1388517428876976 0.3148047818604211 2.42568278788952 1.8971625900564304 0.9268276914308484 0.2996934003616133 0.0010705736616378 1.0 0.3196260593385788 0.0023124348467711 0.0004730993907641 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 5 6 2.1934801417141827 0.0282728038113517 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0050382705358123 0.0573151884822011 0.0058956460302812 0.032628233248221 0.0019884945269669 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 2 7 2.115168144752169 0.0344156189151507 2.6067961165048543 7.0 0.7914914082442276 0.4366893661235884 1.5075062759483802 0.0 0.8715475629418188 0.3304871916560691 0.0008979538364946 1.0 1.0 0.0112385866308786 0.0034377129995212 +Glycoside hydrolase superfamily [IPR017853] 7 15 2.066553757786412 0.0387762219519802 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 9.166138454978089e-06 1.0 1.0 0.1292409073430241 2.0974178082134003e-05 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ff28ae0b7867374fc17e707dd206849f92514df5 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 987, + "title": "Average number of proteins per term", + "value": 4.6453900709219855 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f648fad0c9e801b48d75e6bec68d7527fa2b6927 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2b3e61a81156bb1aaec932420b7f1422f654d77d --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,120 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7406716587347785 3.2558550263308454 0.0011305145969235 0.6725595613436457 0.4566591217778804 23 Q00325,P12236,Q9NZJ7,Q9UBX3,Q96H78,Q70HW3,Q9Y6C9,Q9BQT8,Q9Y619,Q9H2D1,Q9HC21,O43772,P12235,Q6NUK1,P16260,Q9BSK2,P05141 17 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.843332381192831 2.3019189181843065 0.0213397451280803 0.9999999994328004 0.4566591217778804 6 Q9NZ08,Q9UIQ6,P55786 3 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.843332381192831 2.3019189181843065 0.0213397451280803 0.9999999994328004 0.4566591217778804 6 Q9NZ08,Q9UIQ6,P55786 3 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5843343925813596 2.2264163579000367 0.0259863057977605 0.9999999999948272 0.4566591217778804 21 Q9UHG3,Q8NBM8,Q6NUM9,O95831,Q9H9P8,Q16134,Q96CU9 7 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8186060983198604 2.1934801417141827 0.0282728038113517 0.9999999999994916 0.4566591217778804 6 O15173,O43169,Q8WUJ1,Q9UMX5,O00264 5 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.7749507163238163 2.115168144752169 0.0344156189151507 0.999999999999999 0.4566591217778804 7 Q10713,P22695 2 +Glycoside hydrolase superfamily [IPR017853] 0.6233537651253125 2.066553757786412 0.0387762219519802 1.0 0.4668814062868817 15 Q9BTY2,P04062,P04066,P54802,O60502,P06865,P06280 7 +Porin domain superfamily [IPR023614] 0.86691542288557 1.9471061963359984 0.0515220043018735 1.0 0.4724740437491052 4 Q9Y277,P21796,P45880 3 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.5716967546199629 1.8844410056851253 0.0595053476051017 1.0 0.4724740437491052 17 P49721,P28070,P20618,P28074,P28072,Q99436 6 +P-type ATPase, A domain superfamily [IPR008250] 0.7828926905132111 1.880923714687644 0.0599822967609045 1.0 0.4724740437491052 5 Q9HD20,P05023,P98194,P16615 4 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7828926905132111 1.880923714687644 0.0599822967609045 1.0 0.4724740437491052 5 Q9HD20,P05023,P98194,P16615 4 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7828926905132111 1.880923714687644 0.0599822967609045 1.0 0.4724740437491052 5 Q9HD20,P05023,P98194,P16615 4 +SNARE [IPR010989] 0.6997157709538704 1.8767424777771224 0.0605533977068004 1.0 0.4724740437491052 8 O43752,O60499 2 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8310970769408129 1.8023323267485003 0.0714931353901686 1.0 0.5038445131634526 4 P42892 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9459123406900792 1.706464136438597 0.0879216981132899 1.0 0.5336889181016543 3 O43657,O60637 2 +LEM/LEM-like domain superfamily [IPR011015] 0.69212180807193 1.6183096224203657 0.105595888009256 1.0 0.5762742077350833 6 P50402,Q86XL3,P42167 3 +GOLD domain superfamily [IPR036598] 0.7849755497240427 1.613431755742714 0.1066507386357935 1.0 0.5762742077350833 4 Q9Y3B3,Q15363 2 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.6275303643724548 1.6124309717008882 0.1068681897223322 1.0 0.5762742077350833 9 Q9BUF5,P68371,P04350,P07437,Q9BUK6,Q9BVA1,Q13885,Q13509 8 +Ricin B-like lectins [IPR035992] 0.7819694196187692 1.6010342252601455 0.1093693389064629 1.0 0.5762742077350833 4 Q8N4A0 1 +GINS, helical bundle-like domain superfamily [IPR036224] 0.7696573983819534 1.5501635472767126 0.1211022666888301 1.0 0.5997772128300116 4 Q9Y248 1 +START-like domain superfamily [IPR023393] 0.9018396186065004 1.542050344462757 0.1230613601150116 1.0 0.5997772128300116 3 Q9NQZ5 1 +Tubulin, C-terminal [IPR023123] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.6139399676610118 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.6139399676610118 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.6139399676610118 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Alpha/Beta hydrolase fold [IPR029058] 0.4843767810644849 1.4889813829620715 0.136492271204744 1.0 0.6144733070758733 26 Q9H3G5,P42785,Q8NCC3,Q9HB40,P10619,Q9UMR5,P50897 7 +Cytochrome P450 superfamily [IPR036396] 0.8778304005128176 1.4520813070181855 0.1464789989106387 1.0 0.6340998768631598 3 Q16850 1 +NAP-like superfamily [IPR037231] 0.875038856077089 1.441609418104096 0.1494125900346872 1.0 0.635462825947877 3 Q99733,P55209 2 +Tim10-like domain superfamily [IPR035427] 0.873484612993471 1.4357782915314543 0.1510654388898209 1.0 0.635462825947877 3 Q9Y5J9,P62072 2 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.6451729882915309 1.397189113641966 0.1623567095242619 1.0 0.6487695234835893 6 Q13423,A1L0T0 2 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.727637607459319 1.375605349090378 0.1689438497299833 1.0 0.6696689947128255 4 Q13438,P20645 2 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.8462679087525489 1.3336289073540444 0.1823255043209879 1.0 0.6842405808548101 3 P54802 1 +Histidine phosphatase superfamily [IPR029033] 0.6280738445077985 1.3159323920333963 0.1881967355432858 1.0 0.6894019317565511 6 Q9NPH0 1 +Rhomboid-like superfamily [IPR035952] 0.7904880323282348 1.1248644882777925 0.2606464621891227 1.0 0.7455438790895933 3 Q9BUN8,Q9H300 2 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9220012430080702 1.1171980630200629 0.2639096486310279 1.0 0.7455438790895933 2 A6NIH7 1 +MFS transporter superfamily [IPR036259] 0.5351312480349726 1.112981258240334 0.2657164788181041 1.0 0.7455438790895933 9 O00400,Q96ES6,P53985,Q9H2V7 4 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.7788024239418911 1.0814175611691446 0.2795114134452943 1.0 0.7455438790895933 3 P49356 1 +Glycosyl hydrolase, all-beta [IPR013780] 0.5400889175497632 1.05702818240622 0.2904987255625446 1.0 0.7463735160899918 8 Q9BTY2,P04066,P06280 3 +Zinc-binding ribosomal protein [IPR011332] 0.6498756218905424 1.051491456137155 0.2930329313937743 1.0 0.7463735160899918 4 P61927,P42677,P83881 3 +RmlC-like jelly roll fold [IPR014710] 0.5302424355267313 1.005497689595291 0.3146572614231608 1.0 0.7725540224494024 8 Q9BV57,Q9Y4G8,P38435 3 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.5293092939528569 1.0006162806793513 0.3170123559988638 1.0 0.7764049512925026 8 Q92804,P98175,P35637 3 +HAD superfamily [IPR023214] 0.4097653994247522 0.9525673495203154 0.3408093268078582 1.0 0.8021591679616822 20 P98194,P05023,Q8WVY7,Q9H857,P16615,Q969T7,Q9HD20 7 +HAD-like superfamily [IPR036412] 0.4097653994247519 0.9525673495203136 0.3408093268078591 1.0 0.8021591679616822 20 P98194,P05023,Q8WVY7,Q9H857,P16615,Q969T7,Q9HD20 7 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.5308630612858494 0.9252014890696144 0.3548611090901055 1.0 0.8106946995717978 7 O75027,P08183 2 +Ferritin-like superfamily [IPR009078] 0.8660658794282167 0.915217093567991 0.3600776726613151 1.0 0.8106946995717978 2 Q7LG56 1 +Ribonucleotide reductase-like [IPR012348] 0.8660658794282167 0.915217093567991 0.3600776726613151 1.0 0.8106946995717978 2 Q7LG56 1 +CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130] 0.8620261031696709 0.9009167637933329 0.3676325773299935 1.0 0.8121339078158355 2 O14735 1 +Chloride channel, core [IPR014743] 0.8415164698570392 0.8290866682633338 0.4070553670460555 1.0 0.8374215324965151 2 P51798 1 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.4260427223144424 0.797717243442162 0.4250345949966005 1.0 0.849208796076204 15 Q6NXT1 1 +Cytochrome c oxidase, subunit VIIa superfamily [IPR036539] 0.8144810441267694 0.7366995396166492 0.4613050868779371 1.0 0.8665188151345892 2 P14406 1 +RmlC-like cupin domain superfamily [IPR011051] 0.5722171962683438 0.7352460097510106 0.4621896827612106 1.0 0.8665188151345892 4 Q9BV57 1 +GYF-like domain superfamily [IPR035445] 0.811995027967684 0.7283547316849925 0.4663964665101874 1.0 0.8680688163017856 2 O95400 1 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.7952144188937018 0.6727752050775152 0.5010903143306771 1.0 0.8866744152041499 2 P23786 1 +Bcl-2-like superfamily [IPR036834] 0.5509845774055917 0.6522245431902204 0.5142563292364493 1.0 0.8877102075368001 4 Q07820,Q9BXK5 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.8909221273516107 2 P10321 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.8909221273516107 2 P10321 1 +PX domain superfamily [IPR036871] 0.40873925945016 0.5873730117479483 0.5569532153222849 1.0 0.8909221273516107 12 Q9Y2I1,Q96S38 2 +NTF2-like domain superfamily [IPR032710] 0.460443382138099 0.5821017404069624 0.5604981529329982 1.0 0.8909221273516107 7 Q9UBU9,O43615,Q9BRJ2 3 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3584490128226988 0.5673461743587919 0.5704790116375056 1.0 0.8909221273516107 20 Q8N4A0,Q10472 2 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.4322904204317815 0.5582567746132707 0.5766690570116579 1.0 0.8946917446393624 9 Q15067,O15254 2 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.4322904204317815 0.5582567746132707 0.5766690570116579 1.0 0.8946917446393624 9 Q15067,O15254 2 +Methylthiotransferase, N-terminal domain superfamily [IPR038135] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.8967688126235734 2 Q5VV42 1 +Radical SAM, alpha/beta horseshoe [IPR023404] 0.7563704164076819 0.5498824401949363 0.5824000090088253 1.0 0.8967688126235734 2 Q5VV42 1 +Cyclic nucleotide-binding-like [IPR018490] 0.519675753615847 0.5342891633495174 0.5931414885010615 1.0 0.906239394969888 4 Q9Y4G8 1 +Fibronectin type II domain superfamily [IPR036943] 0.7470478558110677 0.5217718657587217 0.6018291805933988 1.0 0.9124506931577336 2 Q9UBV2 1 +Kringle-like fold [IPR013806] 0.7470478558110677 0.5217718657587217 0.6018291805933988 1.0 0.9124506931577336 2 Q9UBV2 1 +Rhodanese-like domain superfamily [IPR036873] 0.5057224605421061 0.483882420913087 0.6284693168378501 1.0 0.9304785435996082 4 P25325 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.3805603871329958 0.4468559750229272 0.6549790528400818 1.0 0.9304785435996082 13 P35613,Q08722,Q9Y639,P10586,P10321 5 +EF-hand domain pair [IPR011992] 0.3473360789711602 0.4374901493681534 0.6617559184419242 1.0 0.9304785435996082 53 Q9NWM8,O95202,Q02818,Q14257,Q8NF37,Q9Y680,O43852,P41208,Q6NUK1,P80303,Q8IYU8,O75071,P14649,O75340 14 +ESCRT assembly domain [IPR037202] 0.7110006215040319 0.4190296842656615 0.6751944382794366 1.0 0.9304785435996082 2 Q99816 1 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.7069608452454695 0.4081579777360974 0.6831576971328479 1.0 0.9304785435996082 2 Q9NRV9 1 +Lamin tail domain superfamily [IPR036415] 0.5781507724258742 0.4001261167112441 0.6890636290846668 1.0 0.9304785435996082 3 Q03252 1 +EB1, C-terminal domain superfamily [IPR036133] 0.7026103169670559 0.3966053688864076 0.6916584928013907 1.0 0.9304785435996082 2 Q15555 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3452907750249698 0.3841853761946202 0.7008410563034286 1.0 0.9335089373434332 18 Q9H7Z7,Q13505,Q9Y696,O75431,P78417 5 +Death-like domain superfamily [IPR011029] 0.4682812042575232 0.3570025231913323 0.7210899168093523 1.0 0.946430515812275 4 Q13546,Q7Z434 2 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.4614427860696441 0.3353596210860643 0.7373538237605481 1.0 0.952717393135212 4 Q8TC07,Q9Y3P9,Q66K14 3 +L27 domain superfamily [IPR036892] 0.4211634558019329 0.3131274510075179 0.7541838341473339 1.0 0.954320142668666 5 Q14168,Q8N3R9 2 +Proteasome activator superfamily [IPR036252] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.9595771748114352 3 P61289 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.9595771748114352 3 P61289 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.5304755569460793 0.275937763264859 0.7825958685762759 1.0 0.9595771748114352 3 P61289 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.9595771748114352 2 P40763 1 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.9595771748114352 2 P40763 1 +STAT transcription factor, coiled coil [IPR015988] 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 0.9595771748114352 2 P40763 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.6500932256059753 0.2709372929551426 0.78643926173864 1.0 0.9595771748114352 2 P05026 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.6494717215661919 0.269612623956344 0.7874582873818525 1.0 0.9595771748114352 2 P61927 1 +BSD domain superfamily [IPR035925] 0.648850217526423 0.2682919460532742 0.7884746051679421 1.0 0.9595771748114352 2 Q96A49 1 +CAP Gly-rich domain superfamily [IPR036859] 0.5144544606776591 0.239446292385386 0.8107595376480747 1.0 0.9646296768656948 3 Q14203,Q99426 2 +Oxysterol-binding protein superfamily [IPR037239] 0.4284825870646682 0.2388936149154728 0.8111880767968862 1.0 0.9646296768656948 4 Q9BXB4,P22059,Q9BZF1 3 +HotDog domain superfamily [IPR029069] 0.3855009334163103 0.2294800038782445 0.8184958605768604 1.0 0.9661945298222864 6 Q9Y305,P51659,Q8WUY1,O14734,O00154 5 +PapD-like superfamily [IPR008962] 0.505750699409397 0.220823354262834 0.8252299783588524 1.0 0.9661945298222864 3 Q9P0L0,Q8NHP6 2 +CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635] 0.5929148539465618 0.1662546544089056 0.8679565498720567 1.0 0.9854429183819248 2 Q9NZN8 1 +BAG domain superfamily [IPR036533] 0.4724898974199626 0.1577879641935169 0.8746238830278774 1.0 0.987167532172887 3 Q9UL15,O95429 2 +SH2 domain superfamily [IPR036860] 0.3380062305296029 0.1464494958687154 0.8835665564181183 1.0 0.987167532172887 10 Q06124,P42224,P46108,P46109,Q7KZ85,P07948,P40763,P22681,P62993 9 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.4588125582841206 0.1356888117175192 0.892067292870153 1.0 0.9904054196432408 3 Q53H12,Q9NRA0 2 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.4588125582841206 0.1356888117175192 0.892067292870153 1.0 0.9904054196432408 3 Q53H12,Q9NRA0 2 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.5577998756992049 0.1193781937880295 0.9049757365768052 1.0 0.9976023000679216 2 Q9BYT8 1 +Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151] 0.5543816034804356 0.1155018075087103 0.9080473878817736 1.0 0.9976023000679216 2 Q6P6C2 1 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.4401616412807076 0.1091462497393269 0.9130864919962576 1.0 0.9976023000679216 3 Q5T440,Q969Y2 2 +Prefoldin [IPR009053] 0.3644278606965117 0.0949713556294439 0.9243375789532442 1.0 0.9992565064916232 4 Q9UHV9,O60925,P61758 3 +p53-like transcription factor, DNA-binding [IPR008967] 0.4233758159776284 0.0887266206295256 0.9292991757641452 1.0 1.0 3 P40763,P42224 2 +Peptidase M41-like [IPR037219] 0.5180236171535259 0.0812851277443105 0.935215201190362 1.0 1.0 2 Q9Y4W6 1 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.5130515848353159 0.0775419038551725 0.9381924571474364 1.0 1.0 2 P06576 1 +Ribosomal protein L22/L17 superfamily [IPR036394] 0.5093225605966585 0.0748713273299741 0.9403170899824596 1.0 1.0 2 P18621 1 +Translation Initiation factor eIF- 4e-like [IPR023398] 0.481354878806728 0.058303567505583 0.953506825892736 1.0 1.0 2 P06730 1 +PUA domain superfamily [IPR036974] 0.4729645742697491 0.0544150519412746 0.956604486907176 1.0 1.0 2 Q9Y221 1 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.4518334369173572 0.0465023263865778 0.962909879905742 1.0 1.0 2 Q9Y3E5 1 +Profilin superfamily [IPR036140] 0.4449968924798187 0.0444541761679887 0.9645423779606166 1.0 1.0 2 P35080 1 +CRIB domain superfamily [IPR036936] 0.4425108763207075 0.0437649812142079 0.965091741267005 1.0 1.0 2 Q13153 1 +ArfGAP domain superfamily [IPR038508] 0.4390926041019443 0.042863445634055 0.9658103881125712 1.0 1.0 2 Q8N6T3 1 +ARFGAP/RecO-like zinc finger [IPR037278] 0.4390926041019443 0.042863445634055 0.9658103881125712 1.0 1.0 2 Q8N6T3 1 +HIV integrase-binding domain superfamily [IPR036218] 0.4344313238036226 0.041716614398414 0.9667246091159094 1.0 1.0 2 Q7Z4V5 1 +Tautomerase/MIF superfamily [IPR014347] 0.4322560596644014 0.0412126926328908 0.9671263350125628 1.0 1.0 2 P14174 1 +Ribosomal protein L14 superfamily [IPR036853] 0.4210689869484328 0.0389125600684594 0.9689601026675534 1.0 1.0 2 Q6P1L8 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.3104125086558342 0.036599783052646 0.9708041165147046 1.0 1.0 10 O60502 1 +Band 7/SPFH domain superfamily [IPR036013] 0.3171694106757965 0.0339769487103194 0.972895532350003 1.0 1.0 8 Q99623,O75955,Q9UJZ1,P27105 4 +Dimeric alpha-beta barrel [IPR011008] 0.3620261031696811 0.0326129631007836 0.9739832322705272 1.0 1.0 2 O75323 1 +Pyruvate kinase-like, insert domain superfamily [IPR011037] 0.315724052206351 0.0313024140646198 0.975028365207688 1.0 1.0 2 Q5VT66 1 +AF1104-like superfamily [IPR036075] 0.270043505282798 0.0310055746931871 0.9752650938494238 1.0 1.0 2 Q9NVE7 1 +Metal-dependent hydrolase [IPR032466] 0.3088825475218332 0.0179118516821012 0.98570917425637 1.0 1.0 5 P00813 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069] 0.3099078408013365 0.0127941374870156 0.989792033721336 1.0 1.0 8 P49748,Q15067 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3a0e1684c2e78904bad32e9daf8d9858ee01c8f8 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper homeostasis (CutC) domain superfamily [IPR036822]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IA, central region, subdomain 1 [IPR013824]", "DNA topoisomerase, type IA, central region, subdomain 2 [IPR013825]", "DNA topoisomerase, type IA, central region, subdomain 3 [IPR013826]", "DNA topoisomerase, type IA, core domain [IPR023405]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Decaprenyl diphosphate synthase-like superfamily [IPR036424]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarate reductase/succinate dehydrogenase, transmembrane subunit [IPR034804]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GLE1-like superfamily [IPR038506]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrase-like, N-terminal [IPR017856]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylated DNA-protein cysteine methyltransferase domain superfamily [IPR036631]", "Methylated DNA-protein cysteine methyltransferase, DNA binding domain [IPR036217]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "Mitochondrial ribosomal protein L55 superfamily [IPR044884]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S1, PA clan, chymotrypsin-like fold [IPR043504]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPB6/omega subunit-like superfamily [IPR036161]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S27, zinc-binding domain superfamily [IPR023407]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transcriptional regulator TACO1-like, domain 3 [IPR026564]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPA domain superfamily [IPR037129]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YebC-like [IPR029072]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATXN10", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL2L12", "BCL2L13", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOP1", "BRAT1", "BRD2", "BRD4", "BROX", "BSDC1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK6", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNN2", "CNN3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "CYP7B1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDHD2", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INTS14", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN2A1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED21", "MEPCE", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL55", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAB1", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX13", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLEC", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAAL1", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF4", "SCCPDH", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMS", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX4", "STX5", "STX6", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACO1", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMEM62", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOR3A", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TST", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXN2", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VKORC1L1", "VPS11", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WNK1", "WRAP53", "WRAP73", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XXYLT1", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YOD1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZFR", "ZFYVE16", "ZMYND8", "ZNF148", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCB7", "ACADVL", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ADA", "ADI1", "AFG3L2", "AGK", "AIFM1", "ALKBH5", "ANKLE2", "ANKRD54", "ARFGAP1", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2C1", "ATP5B", "BAG4", "BAG5", "BCL2L13", "BSG", "CALU", "CBL", "CD2BP2", "CD47", "CDIPT", "CDKAL1", "CETN2", "CLCN7", "CLIC4", "CNOT2", "COX7A2", "CPT2", "CPVL", "CRK", "CRKL", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DCTN1", "DERL1", "ECE1", "EFCAB14", "EIF4E", "EMD", "ERAP1", "ETFDH", "FKBP14", "FKBP7", "FLOT1", "FNTB", "FOXRED1", "FUCA1", "FUCA2", "FUS", "GALNT1", "GALNT4", "GBA", "GGCX", "GINS2", "GLA", "GRB2", "GSTO1", "GTPBP3", "HDGFL2", "HEBP1", "HEXA", "HLA-C", "HSD17B4", "IBA57", "ILVBL", "L2HGDH", "LETM1", "LMNB2", "LNPEP", "LPCAT1", "LYN", "M6PR", "MAPRE2", "MARC1", "MAVS", "MCL1", "MFSD3", "MGEA5", "MICU2", "MIF", "MOSPD2", "MPP2", "MPP5", "MPST", "MRPL14", "MRPL45", "MSTO1", "MTCH1", "MTCH2", "MTX1", "MTX2", "MYL6B", "NAGLU", "NAP1L1", "NAP1L4", "NENF", "NIP7", "NIPSNAP2", "NISCH", "NLN", "NNT", "NPEPPS", "NPTN", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "NXF1", "OS9", "OSBP", "OSBPL11", "OSBPL8", "PAK1", "PANK4", "PARL", "PCYOX1", "PCYOX1L", "PDCD6", "PFDN1", "PFDN2", "PFN2", "PGRMC1", "PGRMC2", "PHB2", "PLA2G15", "PMPCA", "PPT1", "PPT2", "PRCP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSME3", "PTGES2", "PTPN11", "PTPRF", "PTRH2", "RABGAP1", "RAPGEF2", "RBM10", "RCN2", "RETSAT", "RIPK1", "RPL17", "RPL36A", "RPL37", "RPS27", "RPS6KC1", "RRM2B", "SCPEP1", "SEL1L", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A16", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC33A1", "SPHK2", "SPNS1", "STARD7", "STAT1", "STAT3", "STOM", "STOML2", "STX10", "STX6", "SUPT6H", "SYAP1", "TAF15", "TBC1D15", "TBC1D9B", "TBCB", "THEM6", "TIMM10", "TIMM44", "TIMM8B", "TMED2", "TMED7", "TMPO", "TSG101", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBLCP1", "UNC119B", "UQCRC2", "VAPA", "VBP1", "VDAC1", "VDAC2", "VDAC3"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f0b779b42da09f7b94464fb2ea46979ce5cf5b4f --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f9300548efcf1bd98de1c327516704ad8eddb2d5d6df974dc2d745e4f1b2225 +size 70920 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..696dcb443560f630f2c6acbfb48228449b942208 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5de4a70ca411d0155f573a1199ea3fdf78c274a5 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..030dc6c6fff07c56a0399113e2a046760140b8c1 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7828926905132111 1.880923714687644 0.0599822967609045 0.2191922222298693 0.239929187043618 5 Q9HD20,P05023,P98194,P16615 4 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6d47223ef9efe18c9e270d36281b8a4d2e5b424b --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "EIF5A", "FASN", "NDUFAB1", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a3648a2aea5f01e44000815124fa16f0f8fbc5f0 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0519e99dd42a26f6f9678ea8548268ec85e5b655688decd5524af6d42e650dac +size 186758 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c1d68e3ac42ea6fbd952202c9b998536bc2ffad7 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:caebb9729dc38b0c80c2f35feee22c3b843eb27282ede6d0f4d1365c29ca918b +size 149059 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9b0dc083d9fe8434b7c464baa16a2c7138cfd52a --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e850854fdf57a23900f8813a07b651db7575634ed0db7d467317f8a1dec957ef +size 73982 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f68f1d863793fdbe9161ffe0efcf5c2542138779 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 17 23 3.255855026330845 0.0011305145969235 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.506811130714988e-05 0.1706778675257841 0.0532804729840314 2.679082783141478e-06 1.279082532544537e-07 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9dc5b85e21fab089ccab13082ae6a3cd91ef8038 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 72, + "title": "Average number of proteins per term", + "value": 5.555555555555555 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9c3fcba0c1def66d544079727beb7046e8ea3ec1 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f7fa6853a714c5d16060abdb3d300853de68f1dc --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7406716587347785 3.2558550263308454 0.0011305145969235 0.0782148383405517 0.0813970509784987 23 Q00325,P12236,Q9NZJ7,Q9UBX3,Q96H78,Q70HW3,Q9Y6C9,Q9BQT8,Q9Y619,Q9H2D1,Q9HC21,O43772,P12235,Q6NUK1,P16260,Q9BSK2,P05141 17 +HEAT repeat [IPR000357] 0.4904034404427807 0.725815563751214 0.4679518444387103 1.0 0.7657393818087986 7 Q6PJG6,Q8TEX9,O00410 3 +PFTB repeat [IPR001330] 0.7666252330639938 0.5814602188699567 0.5609303219860713 1.0 0.8681281858486107 2 P49356 1 +Tetratricopeptide repeat 2 [IPR013105] 0.3773702207025196 0.0482805397770022 0.961492663473316 1.0 0.9770168504360592 3 Q02790,P31948 2 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..10f0a831cd9d46622457b3d0f35410c2c757ff3c --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN2", "ACTN4", "AGAP3", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKRD17", "ANKRD54", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DYNC1I2", "EDC4", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HTT", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "JUP", "KDELC2", "KDM2A", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NLRX1", "NOL10", "NOP2", "NOP9", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF39", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "SART3", "SCML2", "SCRIB", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SIN3A", "SIN3B", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS11", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", 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0.0039807104422884 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0101953907098773 0.3228460923172884 0.181453052630302 0.0028924350901622 0.0139863775550018 +Membrane lipid biosynthetic process 15 26 2.8736582922911285 0.0040574769456067 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0123821289634062 1.0 0.1920773275443584 0.0035695402472551 0.0019425965813982 +Regulation of ph 13 21 2.858399875691463 0.0042578345538482 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0206154921814175 0.0267403422938185 0.0142951840993497 0.0362911702166911 0.0007920809146458 +Regulation of cellular ph 13 21 2.858399875691463 0.0042578345538482 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0162784953980453 0.0239365913087713 0.0121710399777804 0.0300192966842153 0.0005033411943392 +Anion transmembrane transport 27 41 2.8497882706251887 0.0043748341212599 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 3.4674664057596136e-05 0.4251307382490726 0.0973635670841622 1.5523970851403116e-05 6.692467974427642e-06 +Ion transmembrane transport 71 158 2.848841291235786 0.0043878763033642 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 6.053801204867672e-05 0.0065241612517609 0.0016583417034473 1.477085145301308e-05 3.020930987892828e-07 +Cellular ion homeostasis 35 89 2.836850735523304 0.0045560906329267 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.2125511005226137 0.3887258576445169 0.1301217042464607 0.4894098122577798 0.0135427981581155 +Sphingolipid biosynthetic process 10 18 2.82353444822203 0.0047497321423533 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0334834596358433 1.0 0.4418810858922499 0.0136344588869589 0.0234193598976723 +Alcohol metabolic process 27 90 2.82305237327147 0.0047568800199593 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 0.0006585700645335 0.2734905720891787 0.0044027550207007 0.0005342510330967 9.427835207809928e-07 +Organic acid transmembrane transport 15 32 2.7905352541900506 0.0052620969253434 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.002949034318618 1.0 0.5468718822386345 0.0031061282245647 0.0001129876503173 +Cytochrome complex assembly 7 14 2.78384166378098 0.005371925113847 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0034391300197074 0.1541506060207377 0.0435975481844182 0.0479498850625808 0.0001729005795719 +Hormone metabolic process 11 28 2.7665525762983263 0.0056652448855847 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0757504147186856 0.3806666514303258 0.6173373514085678 0.0296866330747937 0.002487044867352 +Inorganic ion transmembrane transport 44 114 2.756742385775741 0.0058380326055726 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0085708029943835 0.0254310510346749 0.050645624714131 0.0038168658945258 0.0005853164582709 +Liposaccharide metabolic process 11 18 2.755338846533745 0.005863137971501 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0018173194137189 1.0 0.4363210249842685 0.0509365284789281 0.0017715044959542 +Protein localization to mitochondrion 25 63 2.75434913403965 0.0058808996048613 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 2.344437620421376e-05 0.0157967173614079 1.0230728898165254e-06 1.067331440402548e-05 1.970070511196497e-07 +Cellular monovalent inorganic cation homeostasis 14 25 2.7288948038630285 0.0063546971928878 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.037903638570185 0.0358926009784828 0.0218582842409203 0.0593060830293246 0.000641595952047 +Transmembrane transport 107 222 2.7199425374852297 0.0065293261630836 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 2.2856896496736033e-09 0.0002365203180816 2.112301680737224e-07 8.859923016093688e-10 2.3608333364503305e-13 +Monovalent inorganic cation homeostasis 14 26 2.689699999116296 0.0071516278747278 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0716610174602546 0.0496758524768897 0.0347449548593629 0.0994768290011166 0.0026289561565188 +Nucleotide transport 11 13 2.6725610536373514 0.0075274675301322 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0074678642166531 0.1201219647894398 0.2263045436956677 0.0032545859437725 0.0012730265791845 +Respiratory chain complex iv assembly 4 9 2.6368295686414065 0.0083684865078594 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0064716127922198 0.1157751708195439 0.0246740936940832 0.0215683584236732 0.0062616815035888 +Sterol metabolic process 18 42 2.616911274121746 0.0088729401707203 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 5.0788578278733854e-05 0.0650462755169659 0.0001791038943355 3.55842041397339e-05 1.6606015152181676e-08 +Cation transmembrane transport 49 124 2.586242951751577 0.0097028511964047 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0204266153549663 0.0095169702930689 0.011003621744157 0.0091280992797471 0.0006323175503873 +Vacuolar acidification 5 9 2.559961967218448 0.0104683619010752 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 0.0018515165641455 0.0034296220851759 0.0006712136127385 0.0086586519898169 0.0001429815632908 +Protein transmembrane transport 19 28 2.559300030517182 0.0104883177695151 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 2.7662073988402272e-05 0.0001255471891058 7.525448507746417e-07 3.5525803469399624e-05 1.0029805990324731e-06 +Mitochondrial membrane organization 29 53 2.545369876777801 0.0109162040575436 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 3.301756277927851e-05 0.0803423183551439 0.0145498805195169 1.86285744889917e-05 0.0002054712681025 +Sterol biosynthetic process 12 27 2.525225582958434 0.0115624043257833 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 0.0005058918179509 0.0221396463904123 0.0011244794942918 0.0008698664710281 2.192271601565118e-07 +Mitochondrial cytochrome c oxidase assembly 3 8 2.522438639656899 0.0116544280858665 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.0040207313875964 0.1026081339138497 0.0193632099375005 0.0152248647419399 0.0200033311952484 +Calcium ion import 5 13 2.48467249294604 0.0129670669808523 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.1022477412634134 0.0140700862732742 0.0507931717892238 0.0591065206713347 0.0319540971359957 +Glycoprotein metabolic process 21 72 2.460213734645258 0.0138854295382868 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0001885848797507 0.3045109352268694 0.3826235107094086 0.0211015383584092 0.0006197995216803 +Determination of adult lifespan 1 6 2.4570724818425367 0.0140074421892502 1.4684466019417477 6.878640776699029 0.9172678211727472 0.3356532972350567 1.327993783820954 0.8617154358126836 0.9778379941999832 0.290947936133699 0.0662911939273644 0.066549445548378 0.1289666473793992 0.0435926191526008 0.1457988469723397 +Carboxylic acid transport 13 33 2.443891342819032 0.0145298018217803 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0413029864888177 1.0 0.2752945686830158 0.013435076878633 0.0048014262518894 +Amyloid precursor protein metabolic process 8 22 2.4429662005609623 0.014567101483657 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0063326244995105 0.0296703391700837 0.1012658374302196 0.1467586347483675 0.0012031940780095 +Ph reduction 5 12 2.426100401663389 0.0152620473559104 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0097516962376076 0.0082126449787597 0.002509898486982 0.0291459656321865 0.001918269568256 +Establishment of protein localization to mitochondrial membrane 8 20 2.423626703692547 0.0153663918357007 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 0.0011877087888605 0.0076498462283805 0.0022569298755563 0.0037492480554313 0.0002314752232909 +Peptide catabolic process 5 11 2.421417444719948 0.0154601121970476 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0002090036788304 1.0 0.1709159600444602 6.919512692359094e-05 0.000200465132953 +Intracellular protein transmembrane transport 10 24 2.421222029891485 0.0154684261787867 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0003845581638055 0.0204019662414969 7.346424910355626e-05 0.000686888501954 7.133480197010416e-06 +Chloride transport 9 13 2.411408792099172 0.0158910259346538 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.003007131926098 1.0 0.2780273254227372 0.0010720436073174 0.0008647189955035 +Glycoside catabolic process 4 5 2.4081372477797816 0.0160341519128148 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 1.3281302388111622e-06 1.0 1.0 0.0147480216610697 1.3106068439724131e-05 +Phosphatidylglycerol metabolic process 5 11 2.403994402641026 0.0162170215907964 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.0008216936098927 0.1157751708195439 0.2186221342412543 0.1211421538065826 0.0010205277760807 +Protein targeting to mitochondrion 20 48 2.393191513189155 0.0167025202813104 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 0.0003310020055427 0.0090901991927659 2.173865658007383e-06 4.818008338446824e-05 4.231022986223198e-06 +Phosphatidylethanolamine metabolic process 5 6 2.387636948348637 0.0169570836944905 1.4174757281553398 3.54126213592233 1.2136417130163286 0.2301275972070245 1.0265813928797825 1.052388111444633 1.16214154732605 0.2536389297154525 0.0004880937220283 0.0017760204843955 0.0069232563631819 0.0033170374819039 1.6279070379868977e-05 +Endoplasmic reticulum membrane organization 6 9 2.3702258910248326 0.0177772202927448 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0004880937220283 1.0 0.1203280145079081 0.0033170374819039 0.0002457979454447 +Ceramide biosynthetic process 5 11 2.361866497481478 0.018183188926409 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0899509529230909 1.0 0.2921659829416722 0.051542815486873 0.087821349317486 +Lipid localization 29 75 2.350463603827857 0.0187500412765897 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 4.488648066778357e-05 1.0 0.065964466588521 0.0009263382354536 2.490594477443564e-05 +Mitochondrial respiratory chain complex assembly 17 43 2.343450850533829 0.0191062794172205 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 9.576275082332132e-05 0.0009994289576092 0.0002603673390021 0.0003349624484516 0.0001145680118347 +Regulation of blood pressure 9 20 2.339333039836914 0.0193182040298038 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0313997968956028 1.0 0.4363210249842685 0.0127222619547071 0.0611543838186325 +Steroid biosynthetic process 17 47 2.3351549812564163 0.019535325957394 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0027648992534788 0.0817843887077026 0.0025939624536197 0.0023317569515529 7.800792236748808e-07 +Protein insertion into membrane 11 33 2.333110015840113 0.0196423719221126 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 2.539873377643268e-06 0.0001079185290087 0.0001348318070603 0.0002044748778434 4.207728969627408e-06 +Purine nucleotide transport 8 10 2.328042149709039 0.0199098656389193 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.0218096458546513 0.0937235599037543 0.179062604831997 0.0116756742779249 0.0143001062154138 +Glycosphingolipid metabolic process 6 9 2.326861995204001 0.0199726115224185 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.0173080981321316 1.0 1.0 0.1887844423268079 0.07392944267488 +Mitochondrial calcium ion transmembrane transport 6 11 2.3243890084277763 0.0201046541363938 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.0840307903449433 0.0756950383436983 0.1459927402947744 0.0557098434243155 0.0062633876942655 +Regulation of lysosomal lumen ph 3 6 2.317572218289526 0.0204725815316992 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0008878528391423 0.0023758658868836 0.0003823532959252 0.000366006536683 0.0048822579474643 +Endoplasmic reticulum organization 26 51 2.316212194561686 0.0205466856909832 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 1.740192179119253e-05 0.0060673937801388 0.006515948460693 0.0004690883853953 6.539147531349342e-05 +Organic anion transport 21 47 2.306216849367336 0.0210985185565129 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.0126610685681061 0.5097893650742695 0.1677362543354801 0.0025274832620095 0.0005973315931165 +Lipoprotein metabolic process 8 20 2.3061274676828845 0.0211035109199169 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0450675425020165 0.3426841548479852 0.2027827245191691 0.0166326939811153 0.0536301543799238 +Glycoprotein biosynthetic process 20 64 2.275352739011513 0.0228847780672598 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 6.880870734495458e-05 0.2388207944228527 0.2858633090045295 0.0063206385106294 0.0001315306974784 +Macromolecule depalmitoylation 2 7 2.2359303383681284 0.0253563346506797 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0050382705358123 0.0573151884822011 0.0058956460302812 0.0025975272437437 0.018020673376298 +Amino acid transport 8 20 2.234782956173068 0.0254316013254531 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.3521124126700453 1.0 0.1468141932972727 0.2320869702147383 0.117365177618785 +Secondary alcohol metabolic process 18 46 2.229519239931807 0.0257793766140115 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 6.315072291878632e-05 0.0677466229044455 0.0002035652759605 4.3615601252618245e-05 2.49077739455882e-08 +Oxidative phosphorylation 23 68 2.2240813769286163 0.0261429696286081 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 0.0002683794851084 0.0002772539263296 0.0062100648288004 0.0005914738643724 4.112958037446137e-06 +Protein transmembrane import into intracellular organelle 6 15 2.2133351782649893 0.0268745460371799 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0019454827870102 0.1373006943976843 0.0001962671730819 0.0006827439557333 0.0004675519327548 +Peroxisome organization 8 16 2.2130705336636027 0.0268927832290251 4.286407766990291 11.196601941747574 0.606295801393023 0.4614466229190617 2.3307796330420754 2.613015983661412 0.9820420209440194 0.3193147518558685 0.0674156501807044 1.0 0.2636091346473535 0.0379489226270714 0.0612536211646263 +Multicellular organism aging 1 9 2.209211198396015 0.0271599543440619 2.1674757281553396 10.37864077669903 0.7123407673681669 0.4042486598886041 1.8218230592238136 1.366140512569931 0.923721768654342 0.2985518072202843 0.1333518813406911 0.0981765691424607 0.1871299927573601 0.0901924811619011 0.2715157705871365 +Vitamin transport 5 7 2.2004633632517354 0.0277740365335885 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0055676257230497 1.0 0.2108642126213972 0.0024022577840735 0.0269295467729808 +Cristae formation 6 9 2.1966605376428205 0.0280446992029699 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0662911939273644 1.0 1.0 0.0435926191526008 0.1457988469723397 +Neutral lipid biosynthetic process 1 6 2.184749244930439 0.0289072373208907 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.1985684786213039 0.1244478155008913 0.0285062952815799 0.1374615323876937 0.3798345415961738 +Ceramide transport 2 5 2.16706618020408 0.0302298082324106 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0579592766667772 1.0 0.1203280145079081 0.0379575415698398 0.0225979674873623 +Calcium import into the mitochondrion 3 8 2.164637197621509 0.0304154800221767 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 0.050027591577048 0.0573151884822011 0.1116045715736199 0.032628233248221 0.018020673376298 +Ceramide catabolic process 4 6 2.164363679688884 0.0304364490140967 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 0.0003461886533046 1.0 0.1116045715736199 0.032628233248221 0.0019884945269669 +Sphingosine biosynthetic process 2 5 2.1603062860591127 0.0307489666688829 1.91747572815534 4.20873786407767 0.5236437336099039 0.253544361366954 0.9618880285708752 0.5531212048069467 1.4879043514061585 0.274550754534842 0.0128252824702257 1.0 0.0574361921538736 0.0081566962170519 0.0020376306093415 +Glycoside metabolic process 4 8 2.158514357190389 0.0308878633795013 3.283980582524272 8.611650485436893 0.5062828222010527 0.3204164092287125 1.4990079825210394 0.6824144700308834 1.298018080705215 0.2868097664691992 5.968716101121906e-05 1.0 1.0 0.0495157384890535 0.0005289198821125 +Hormone biosynthetic process 4 8 2.1510644637512746 0.0314711119023167 3.2766990291262137 8.762135922330097 0.5893833627772115 0.3611309387757575 1.7820956292372838 1.0801489024333786 1.1172063688590312 0.2892911953740955 0.5535408319113693 1.0 1.0 0.4704807306772423 0.0074494564855197 +Amino acid transmembrane transport 6 15 2.1472777820590303 0.0317711735432617 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.4223255940150733 1.0 0.3714211816154574 0.3140672800286707 0.0762091064419948 +Glycolipid catabolic process 4 6 2.143482844408168 0.0320743471877211 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 0.0003461886533046 1.0 1.0 0.2541534411772372 0.0019884945269669 +Vitamin transmembrane transport 3 6 2.1352574116807346 0.0327399896240332 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.0008878528391423 1.0 0.1375212864755611 0.000366006536683 0.0048822579474643 +Aminoglycan metabolic process 6 14 2.123094031761047 0.0337459730471045 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0026800339709893 0.2633971592089756 0.4582375595260778 0.1881433143308717 0.0298513421744587 +Transepithelial transport 1 5 2.1079074852046773 0.0350389926427401 1.6553398058252426 4.774271844660194 0.6732735902855568 0.3468688130957016 1.1752486335033188 1.0771313051019258 1.1029852758785914 0.2818815040837556 0.0933798021105754 1.0 1.0 0.0621585272883563 0.1985866733922443 +Proton transmembrane transport 20 45 2.0997089564264377 0.03575445123672 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0078579207926822 0.010878638830109 0.0647665856554279 0.0019103185828395 0.0001635608273434 +Mitochondrion organization 91 204 2.0990723227073 0.0358105258204617 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 4.206206285815412e-08 0.0011409922619743 4.5348569960897735e-06 4.141070633939913e-09 3.250566507828741e-09 +Proton transporting two sector atpase complex assembly 3 6 2.0970337638548218 0.035990586579206 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.0662911939273644 0.066549445548378 0.0080257871552124 0.0435926191526008 0.003721367796782 +Endoplasmic reticulum tubular network organization 8 14 2.0952444889369053 0.0361492642988012 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.013913202095476 0.0802348466038066 0.1543818096433915 0.0621585272883563 0.0078812527225172 +Organic hydroxy compound metabolic process 31 116 2.09208694952718 0.0364307383650708 24.233009708737864 110.8883495145631 0.5334558429683288 0.4627633417898757 8.017219191403747 10.01417249072314 1.2419084217888356 0.3713800795527268 0.0012563834645565 0.4130491949575655 0.022544431674606 0.0015886215622651 9.068230410514844e-06 +Cotranslational protein targeting to membrane 6 14 2.087525102902051 0.0368406943236037 3.0024271844660193 13.269417475728156 0.6346620653188224 0.4380127158001767 2.1905565042006923 1.12246981946818 0.9482238550798552 0.3119643857898596 0.0218096458546513 0.0042324529563037 0.0161297090986061 0.0116756742779249 0.0143001062154138 +Vesicle targeting rough er to cis golgi 6 11 2.087084100553705 0.0368805330165593 3.1067961165048543 10.201456310679612 -0.0499693214735613 0.4614811763227171 1.696155683910704 0.9454529995218351 1.0458529600005972 0.2950501877412649 0.3316493200977276 1.0 1.0 0.2721697661507766 0.4765717690882453 +Inorganic anion transmembrane transport 5 8 2.0832359392744704 0.0372297227006981 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0572624269560779 1.0 1.0 0.0319451393300601 0.1645088237572309 +Endoplasmic reticulum calcium ion homeostasis 5 9 2.081290609865929 0.0374073141359503 3.412621359223301 8.468446601941748 0.7163576234395546 0.3718536853795897 2.0059706805420334 1.5568434939403433 1.1166052913833018 0.3156746531372333 0.4945006235391003 1.0 1.0 1.0 0.088385561156941 +Sphingoid metabolic process 3 6 2.0767625418240723 0.0378234810355697 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0354995311595153 1.0 0.0938999510605359 0.0229613270793894 0.0105668672564949 +Glycerolipid biosynthetic process 28 50 2.0755997988234487 0.0379309800690077 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.0094438316810156 0.2224854546727621 0.2618762982391017 0.0717995711225624 0.0012477452679518 +Fatty acid transmembrane transport 5 8 2.074441699987756 0.0380383079311434 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 0.050027591577048 1.0 1.0 0.2541534411772372 0.018020673376298 +Regulation of steroid metabolic process 7 15 2.073526572603158 0.0381233007643295 4.334951456310679 14.769417475728156 0.4748357054552781 0.3599056508632772 2.2294240946396933 1.955260926764874 1.2378399088740557 0.2930403635554361 0.4739871997048841 1.0 0.4017902994798545 0.3583320648627024 0.0033296386804888 +Mitochondrial protein processing 2 6 2.07229516066927 0.0382379234601983 2.5364077669902914 6.116504854368932 0.6231037550499241 0.4294713635913262 1.5722517118376966 0.4306457304119781 0.9047145170697456 0.2997561714659207 0.2888821858147484 1.0 1.0 0.2356930071839008 0.0140126286640228 +Terpenoid metabolic process 5 19 2.065513661487662 0.0388744242614205 4.992718446601942 17.42233009708738 0.6301104025923489 0.3704291423404849 2.365292196147205 2.02323551503238 1.1104102314092092 0.2862846297230793 0.0354774730168725 1.0 1.0 0.0756846958642696 0.0134528362725409 +Protein quality control for misfolded or incompletely synthesized proteins 3 12 2.058066654922229 0.0395837353907044 2.79126213592233 12.0 0.5975496500899943 0.4916109553523294 2.034918800227117 1.0096620601608022 0.8606428606135228 0.3201479866678081 0.0085600651605588 1.0 0.2339121686337894 0.0264830942684438 0.0397044670530444 +Maintenance of protein location in cell 8 20 2.052266000755014 0.0401438183010793 4.963592233009709 20.74757281553398 0.5138976626555444 0.4828559702191822 2.90064182866346 2.9061984196552437 0.947299732036647 0.3164077327541715 0.0615903601419469 0.2145132052110039 0.0832266786685991 0.0300192966842153 0.0089113675821019 +Triglyceride metabolic process 6 11 2.051956127174677 0.040173926368598 3.4805825242718447 10.771844660194176 0.9779567044833 0.270555786798488 1.9834538010888536 2.3392770219831345 1.099054194056709 0.249087443977639 0.1952619005799098 1.0 0.3898210156705143 0.3407321567572847 0.4404396671456285 +Organic acid transport 24 48 2.049295461510861 0.0404332321889115 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0031022925635837 1.0 0.3899534463534457 0.0017480864507818 0.0009643504563797 +Glycosyl compound catabolic process 7 11 2.044512331776301 0.0409029604099999 3.216019417475728 9.74271844660194 -0.2866012386822237 0.2471021044870933 1.8641835401772064 0.9067280280460008 1.4904201092322935 0.2120144867281597 5.083127208116647e-06 0.1114073342812727 0.2108642126213972 0.0024022577840735 1.0761884384293304e-05 +Sulfur compound transport 3 10 2.0432100409065748 0.0410316502022851 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0173080981321316 0.0112943240362007 0.0412914524019695 0.0078094686864188 0.07392944267488 +Nucleotide transmembrane transport 6 8 2.04293229410456 0.0410591409272662 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0117182537853428 1.0 1.0 0.0061570039439817 0.0007388687073799 +Glucose import 4 12 2.0350813141107955 0.0418426918283958 3.4563106796116503 11.364077669902912 0.3176045676169922 0.5089134846135845 1.8514056534885703 2.196305563870774 0.9183417404528994 0.3012736273802708 0.400938213563647 1.0 1.0 0.6676078298658026 0.1732034237667374 +Atp transport 5 6 2.0341813525398487 0.0419333139621833 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 0.243387780989186 1.0 1.0 0.1973959389561772 0.0675218785318175 +Glial cell proliferation 2 5 2.007384319703456 0.0447087571259059 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.1545530381620926 1.0 1.0 0.1053546389470493 0.0981468657129251 +Alcohol biosynthetic process 16 41 2.0069695184077805 0.0447529087042872 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 7.024382024427783e-05 0.0691107257825923 0.0016898291272514 0.000259969323856 8.756102334620714e-07 +Protein retention in er lumen 4 5 1.9858053489115408 0.04705494161591 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 0.0005249607641283 0.0290719737908623 0.0013923625346842 0.0002629541815867 0.0020376306093415 +Maintenance of protein localization in endoplasmic reticulum 4 5 1.9858053489115408 0.04705494161591 1.203883495145631 3.203883495145631 1.1364527439994954 0.2609157960586762 1.0226486010276945 1.0226486010276945 1.138989616014889 0.2624735143617788 0.0014043590152869 0.0385773062479974 0.0025659780541994 0.0007102815399137 0.0053031795330487 +Dicarboxylic acid transport 5 15 1.9846619194755457 0.0471820982695014 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.1356203230605793 1.0 1.0 0.0801176308941427 0.1451121707049519 +Regulation of glycoprotein metabolic process 7 14 1.9771570947219024 0.0480238757166866 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0097516962376076 1.0 1.0 0.0291459656321865 0.010278445998416 +Response to l glutamate 1 5 1.97476570386334 0.0482947427473008 1.029126213592233 4.37378640776699 1.2967513270419406 0.258405010407401 0.7465949978845596 0.5879801140961596 0.7687098467942305 0.2572187080379352 0.0289747404906159 1.0 0.0849171013653387 0.0186627473263165 0.0675218785318175 +Protein import into mitochondrial matrix 2 9 1.9723168313103487 0.0485734494038383 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0097377531702328 0.0711332726649859 0.0003823532959252 0.0050923434600555 0.0048822579474643 +Embryonic heart tube development 2 7 1.9706078487595728 0.0487687481841034 1.3932038834951457 5.800970873786408 0.4671790151602789 0.3328586203421327 1.1599097835626424 1.1943227471644264 1.1899911587922487 0.2586146658185882 0.2190817498128163 1.0 1.0 0.135543868878084 0.4787405982303483 +Phospholipid transport 2 12 1.9682578790249197 0.049038373731582 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.2031311969341811 1.0 0.3958350013250431 0.124643595331372 0.4533341301651876 +Aerobic respiration 17 93 1.966835867462282 0.0492021360799652 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0003530921088397 0.0010416604701427 0.0046741618874444 0.0004608452787455 2.6998527597199017e-05 +Very long chain fatty acid metabolic process 7 13 1.9607767235801945 0.0499050744559708 3.7135922330097086 10.067961165048544 0.1992178042517653 0.4700770172389826 2.204476845835122 1.726504611418437 1.0263308919544554 0.3000888854469281 0.1763406811395257 0.1157751708195439 0.2186221342412543 0.4573561220916043 0.0308662830144804 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..480e3bc2842cbe0e63270dc3e8e61a50306d8ad1 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 6429, + "title": "Average number of proteins per term", + "value": 19.12739150723285 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bb778f46d93bc9e918fd30a22733c199ed668147 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3aa8221cce89c2b1c7be1f46f789db21208e33b8 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1508 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial transport 0.5537167678548749 3.9745011131564607 7.052693238374097e-05 0.3645574782307308 0.4534176482950771 88 Q99797,Q96EK5,P30536,P50416,P00846,O60830,P62072,Q9Y5J6,Q8N8Q8,P23786,Q9NS69,Q9Y371,O96008,Q9Y584,O75964,O75431,O95831,P45880,Q8N4H5,Q10713,O00165,P24539,P51572,O14737,O43772,Q99595,P55786,Q9Y5J9,P16260,Q15070,Q9H300,Q9UJZ1,P56385,O14925,Q9UBX3,P52789,P12235,Q6NUK1,Q9Y512,O75947 40 +Anion transport 0.6157537390015869 3.706650808245634 0.0002100181976558 0.740850145708944 0.6751034963647978 71 Q9H0H5,Q4KMQ2,Q8TB61,Q9Y619,Q9HC21,P30536,Q15907,P21796,P05141,P51798,Q00325,Q08722,O00400,Q9NW15,Q9Y277,Q9NP80,Q9C0H2,Q9Y6M7,P45880,O43808,P07602,P30825,Q9H2J7,Q9BQT8,Q13546,Q9Y696,P08195,P53985,O60831,P12236,Q96NB2,Q9UBX3,Q9NZJ7,P54105,Q9UHG3,Q9H2D1,P12235,P08183,Q6NUK1,P11166,Q15041,O75915,P51790 43 +Establishment of protein localization to membrane 0.5128363808145499 3.4038587971608503 0.0006644108987849 0.9860589466300228 0.7997756333143134 99 P56589,Q4J6C6,Q9H8Y8,P98194,O15118,Q9BRK0,Q9NPA0,P50542,P49458,Q96A33,P31751,P43307,Q9UHB9,Q15629,P62072,Q9Y5J6,Q15907,P27105,Q8N4V1,Q8N8Q8,O00560,Q9NS69,Q9Y584,Q9H4A6,Q9UHD1,O14737,Q9Y5J9,Q9HD20,Q15070,Q9Y5Y5,O60725,Q99442,Q8N2H4,P46379,P61026,Q9Y512,Q15041,Q5BJH7 38 +Sphingolipid metabolic process 0.7318866062852059 3.2806067605369105 0.0010358405401658 0.9987225255861112 0.7997756333143134 32 Q9P035,P04062,P27544,O95470,P17900,Q96G23,P06865,P50897,P06280,Q8NCC3,Q16739,O15269,Q9NZ01,Q13510,P07602,Q99805,P16278,Q9NZJ7,Q9H2C2 19 +Ceramide metabolic process 0.7442676286258365 3.265200175589271 0.0010938674248108 0.99912064579534 0.7997756333143134 20 Q99805,P04062,P27544,Q8NCC3,O15269,O95470,P17900,Q96G23,Q13510,P06865,P06280 11 +Membrane lipid metabolic process 0.7035807941468327 3.2582384114877287 0.0011210617935775 0.9992618394507616 0.7997756333143134 42 Q9P035,P04062,P27544,O95470,P17900,Q96G23,P06865,P50897,P06280,Q8NCC3,P04066,Q16739,O15269,Q9NZ01,Q13510,Q8NBX0,Q9Y2B2,P07602,Q99805,O43292,P16278,Q9NZJ7,Q9H2C2,Q9H490 24 +Mitochondrial transmembrane transport 0.6391995855055741 3.1349197655843817 0.0017190112081579 0.99998428716719 0.7997756333143134 55 Q96AQ8,Q9Y619,Q8IYU8,P50416,P00846,O60830,P05141,P21796,Q9H4I9,Q00325,P23786,O96008,O75964,O95831,O43615,Q9UJS0,Q8WWC4,Q96ER9,P24539,Q9BQT8,O75027,O43772,Q99595,Q9BSK2,Q6P4A7,Q9UJZ1,P56385,O95202,O14925,P12236,Q96NB2,Q9H2D1,Q15388,P12235,O94826,O75947 36 +Steroid metabolic process 0.5650057012060054 3.105756573357445 0.0018979288714429 0.9999950363958896 0.7997756333143134 69 Q15125,P48449,Q16850,O15118,P04062,Q9H3P7,P35610,P30536,O95470,Q6P1A2,Q15392,Q53GQ0,P05023,P49748,Q9BQE5,Q8WTV0,Q14739,Q13510,Q15800,Q14534,O75845,P16435,P38435,Q9H2C2,P54646 25 +Protein targeting 0.498911176670382 3.0571864850159933 0.0022342522784242 0.9999994313940924 0.7997756333143134 118 P56589,Q99797,P50542,P49458,P13473,P30536,P31751,P43307,Q9UGP8,Q9UHB9,Q15629,P62072,O60830,Q9Y5J6,O14964,P27105,O00560,Q9NS69,Q9Y371,O96008,Q9Y584,O95831,Q9UHD1,Q8N4H5,P57105,Q10713,O00165,P51572,O14737,P61009,Q13438,Q99595,P55786,Q9Y5J9,Q9H300,Q9Y5Y5,Q15005,O14925,O60725,Q14108,Q99442,P46379,Q99523,Q9Y512,Q15041,O75381,Q5BJH7,Q9Y5M8 48 +Inorganic anion transport 0.7034498035933262 3.025902474194554 0.0024789224514776 0.9999998824942338 0.7997756333143134 24 P51798,Q9H0H5,Q00325,Q9UBX3,P54105,Q4KMQ2,Q9NW15,Q9Y277,Q9UHG3,P08183,Q9Y696,P30536,Q9C0H2,Q9Y6M7,P45880,P21796,P51790 17 +Inner mitochondrial membrane organization 0.7001582221209697 3.0047394558234424 0.0026580843593178 0.999999962971444 0.7997756333143134 24 Q9NVH1,Q13505,Q9P0J0,P62072,Q9Y5J6,P17152,O60313,Q9Y584,Q16891,O75431,Q5HYI7,Q6UXV4,Q9Y5J9,Q9BUR5,O95202,Q9H3K2,O94826,Q5XKP0,Q9Y512 19 +Lytic vacuole organization 0.69005237781528 2.9394352606267526 0.003288109544723 0.9999999993628952 0.7997756333143134 24 Q9HC07,Q14108,Q8N511,P04062,O75503,P54802,P11117,O14773,P50897 9 +Cellular hormone metabolic process 0.7244887036632556 2.9296962516124965 0.003392934858617 0.9999999996759968 0.7997756333143134 18 P42892,Q53GQ0,Q9HB40,Q8NBN7,P30536,P09455,O95470 7 +Carbohydrate derivative transport 0.7565528762529958 2.928770661311085 0.0034030540756682 0.9999999996964716 0.7997756333143134 16 P07602,Q08722,P12236,Q9NZJ7,O00400,Q8TB61,P12235,Q6NUK1,Q9HC21,L0R6Q1,P33897,Q8WTV0,P05141 13 +Membrane lipid catabolic process 0.8207607433062322 2.888859976656975 0.0038664120064375 0.9999999999847332 0.7997756333143134 11 P06280,P04062,O95470,Q13510,P06865,P50897 6 +Organophosphate ester transport 0.6801813459565046 2.879686291725067 0.0039807104422884 0.9999999999926994 0.7997756333143134 25 Q08722,P12236,Q14108,Q4KMQ2,Q8TB61,O00400,Q9H2D1,P12235,P08183,Q9HC21,Q6NUK1,P33897,Q8WTV0,Q9BSK2,P05141 15 +Membrane lipid biosynthetic process 0.6784647626646306 2.8736582922911285 0.0040574769456067 0.999999999995552 0.7997756333143134 26 Q9Y2B2,Q99805,Q06136,Q9P035,P04062,P27544,Q16739,O15269,O43292,Q6Y1H2,O95470,Q96G23,Q13510,Q8NBX0,Q9H490 15 +Regulation of ph 0.6789593410884781 2.858399875691463 0.0042578345538482 0.99999999999878 0.7997756333143134 21 Q15904,Q9Y487,Q9HC07,Q8N511,P51790,Q92544,O75503,Q93050,Q9Y696,O75787,Q9Y6M7,Q9UHD1,P50897 13 +Regulation of cellular ph 0.6789593410884781 2.858399875691463 0.0042578345538482 0.99999999999878 0.7997756333143134 21 Q15904,Q9Y487,Q9HC07,Q8N511,P51790,Q92544,O75503,Q93050,Q9Y696,O75787,Q9Y6M7,Q9UHD1,P50897 13 +Anion transmembrane transport 0.6499070461889025 2.8497882706251887 0.0043748341212599 0.9999999999994268 0.7997756333143134 41 Q4KMQ2,Q8TB61,Q9Y619,Q9HC21,P05141,P21796,P51798,Q00325,Q9Y277,Q9Y6M7,P45880,O43808,P30825,Q9BQT8,Q13546,P53985,O60831,P12236,Q96NB2,Q9UBX3,Q9UHG3,Q9H2D1,P12235,P08183,Q15041,O75915,P51790 27 +Ion transmembrane transport 0.5107743155027175 2.848841291235786 0.0043878763033642 0.9999999999994732 0.7997756333143134 158 P05067,P98194,P21281,Q96AQ8,Q4KMQ2,Q8TB61,Q70HW3,Q9Y619,Q9HC21,Q8IYU8,P00846,P62942,P21796,P05141,P27105,P51798,Q8N4V1,Q9H4I9,Q13423,Q00325,O75844,O00400,Q9NW15,Q9Y277,P05023,O75964,Q9C0H2,Q9Y6M7,Q9UHD1,P45880,P20020,O43808,Q9NVV0,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,Q9BQT8,Q9UDW1,Q13546,Q7KZN9,Q9Y696,O75027,O43772,P08195,P13073,O14548,P16615,P53985,Q9HD20,Q6P4A7,Q9UJZ1,P0CG08,P56385,O60831,O75251,P12236,Q96NB2,Q9UBX3,Q9UHG3,Q9H2D1,P12235,P08183,Q96ES6,P78417,O75947,Q15041,Q9BVC6,O75915,P51790 71 +Cellular ion homeostasis 0.4569136090121129 2.836850735523304 0.0045560906329267 0.999999999999822 0.7997756333143134 89 P55061,P05067,P98194,Q96AQ8,Q96A33,Q92544,Q8IYU8,P62942,P50897,Q9H4I9,Q8N511,P05023,Q93050,Q16891,Q9Y6M7,Q9UHD1,O76024,P20020,Q9Y487,P09601,Q9NVV0,Q15904,Q9HC07,P51572,Q9Y639,O75503,O75027,Q9Y696,O75787,P16615,Q9HD20,Q9UJZ1,P0CG08,P78417,P51790 35 +Sphingolipid biosynthetic process 0.7068507525547378 2.82353444822203 0.0047497321423533 0.999999999999949 0.7997756333143134 18 Q99805,Q06136,Q9P035,P04062,P27544,Q16739,O15269,O95470,Q96G23,Q13510 10 +Alcohol metabolic process 0.4566527724039668 2.82305237327147 0.0047568800199593 0.9999999999999514 0.7997756333143134 90 Q86SQ9,Q15125,P48449,Q16850,O15118,P04062,P35610,P30837,Q6NUM9,Q6P1A2,Q15392,O15269,P49748,P51648,Q9BQE5,Q8WTV0,Q14739,Q13510,Q15800,P00374,Q10713,Q14534,O75845,P16435,Q9H2C2,Q8NBN7,P54646 27 +Organic acid transmembrane transport 0.6592863037424027 2.7905352541900506 0.0052620969253434 0.999999999999998 0.7997756333143134 32 O60831,Q96NB2,P30825,P23786,Q9H2J7,Q9UBX3,Q9H2D1,Q9BQT8,Q9Y619,P08183,O43772,P11166,P31751,P53985,Q15041 15 +Cytochrome complex assembly 0.7601376605463419 2.7838416637809797 0.005371925113847 0.9999999999999992 0.7997756333143134 14 Q8N8Q8,Q9Y2R0,Q7KZN9,Q9P0S2,Q9BSK2,P53701,Q15070 7 +Hormone metabolic process 0.6606355505957839 2.7665525762983263 0.0056652448855847 1.0 0.7997756333143134 28 P42892,Q53GQ0,O75844,P05023,Q9HB40,Q8NBN7,P30536,O95470,Q6NUM9,P09455,P16435 11 +Inorganic ion transmembrane transport 0.4710291034262073 2.756742385775741 0.0058380326055726 1.0 0.7997756333143134 114 P98194,P21281,Q96AQ8,Q4KMQ2,Q8IYU8,P00846,P62942,P05141,P21796,P27105,P51798,Q8N4V1,Q9H4I9,Q13423,Q00325,O00400,P05023,O75964,Q9Y6M7,Q9UHD1,P20020,Q9NVV0,Q96ER9,Q9HC07,P24539,Q9H2J7,Q7KZN9,Q9UDW1,O75027,P08195,P13073,O14548,P16615,Q9HD20,Q9UJZ1,P56385,O75251,Q9UBX3,Q9UHG3,P12235,Q96ES6,P78417,O75947,P51790 44 +Liposaccharide metabolic process 0.6956381240070999 2.755338846533745 0.005863137971501 1.0 0.7997756333143134 18 Q9Y2B2,Q99805,P04062,Q16739,P04066,P17900,O43292,Q8NBX0,Q9H490,P06865,P06280 11 +Protein localization to mitochondrion 0.5591522040941992 2.75434913403965 0.0058808996048613 1.0 0.7997756333143134 63 Q99797,P30536,P62072,Q9Y5J6,O60830,Q9NX47,Q8N8Q8,Q9Y6C9,Q9NS69,Q9Y371,O96008,Q9Y584,O95831,Q8N4H5,Q10713,O00165,P51572,O14737,Q99595,P55786,Q9Y5J9,Q15070,O14925,P52789,Q9Y512 25 +Cellular monovalent inorganic cation homeostasis 0.657432668673291 2.7288948038630285 0.0063546971928878 1.0 0.7997756333143134 25 Q15904,Q9Y487,Q9HC07,Q8N511,P05023,P51790,Q92544,O75503,Q93050,Q9Y696,O75787,Q9Y6M7,Q9UHD1,P50897 14 +Transmembrane transport 0.5382236556541355 2.7199425374852297 0.0065293261630836 1.0 0.7997756333143134 222 Q70HW3,Q9HC21,Q8IYU8,Q15629,P00846,O60830,P21796,Q8N4V1,O75844,O00400,Q9NS69,Q9Y584,O75964,Q9C0H2,Q8WTV0,O95831,Q9UHD1,P45880,Q96ER9,Q9H2V7,P30825,Q96H78,P49755,O75027,Q99595,O14548,Q9HD20,Q6P4A7,O14925,O75251,Q9UBX3,Q9UHG3,Q9H2D1,Q6NUK1,P33897,O75947,Q9BVC6,P05067,Q4KMQ2,Q8TB61,P04062,P50542,Q9Y619,P50416,Q9UGP8,P05141,P51798,Q8NHS3,Q9H4I9,Q13423,Q00325,P23786,Q9NW15,P20020,O43808,Q9NVV0,Q9HC07,Q9BQT8,Q9UDW1,Q13546,P08195,P13073,P16260,P0CG08,Q9Y5Y5,P38435,P52789,P12235,P08183,Q96ES6,P78417,Q8IXU6,Q03518,P31751,P62942,Q9Y277,Q9Y6M7,Q8NE01,Q7KZN9,Q9Y696,L0R6Q1,P16615,Q9BSK2,Q99523,O75381,Q99797,P98194,P21281,Q96AQ8,P27105,P05023,O96008,O75298,P24539,Q9H2J7,O43772,P53985,Q9UJZ1,P56385,O60831,P12236,Q96NB2,Q99442,P11166,Q15041,O75915,P51790 107 +Monovalent inorganic cation homeostasis 0.6509499821637615 2.689699999116296 0.0071516278747278 1.0 0.7997756333143134 26 Q15904,Q9Y487,Q9HC07,Q8N511,P05023,P51790,Q92544,O75503,Q93050,Q9Y696,O75787,Q9Y6M7,Q9UHD1,P50897 14 +Nucleotide transport 0.7532170516982104 2.6725610536373514 0.0075274675301322 1.0 0.7997756333143134 13 Q08722,P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 11 +Respiratory chain complex iv assembly 0.8310587775184064 2.6368295686414065 0.0083684865078594 1.0 0.7997756333143134 9 Q9P0S2,Q9Y2R0,Q15070,Q8N8Q8 4 +Sterol metabolic process 0.6164297944358319 2.616911274121746 0.0088729401707203 1.0 0.7997756333143134 42 Q15125,P48449,Q16850,O15118,Q14534,Q9H2C2,P04062,P35610,P49748,Q15800,Q9BQE5,Q8WTV0,O75845,Q6P1A2,Q14739,P16435,Q15392,P54646 18 +Cation transmembrane transport 0.4650411550948666 2.5862429517515775 0.0097028511964047 1.0 0.7997756333143134 124 P05067,P98194,P21281,Q96AQ8,Q4KMQ2,Q70HW3,Q9Y619,Q9HC21,Q8IYU8,P00846,P62942,P21796,P05141,P27105,Q8N4V1,Q9H4I9,Q13423,Q00325,O00400,Q9NW15,P05023,O75964,Q9Y6M7,Q9UHD1,P20020,Q9NVV0,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,Q7KZN9,Q9UDW1,O75027,O43772,P08195,P13073,O14548,P16615,Q9HD20,Q9UJZ1,P56385,O75251,Q96NB2,P12235,Q96ES6,P78417,O75947,P51790 49 +Vacuolar acidification 0.8149337627176052 2.559961967218448 0.0104683619010752 1.0 0.7997756333143134 9 Q8N511,O75503,Q93050,P50897,Q9Y487 5 +Protein transmembrane transport 0.6304289772858688 2.559300030517182 0.0104883177695151 1.0 0.7997756333143134 28 P50542,P31751,Q9UGP8,Q15629,O60830,Q07820,Q9NS69,O96008,Q9Y584,O95831,O75298,P49755,Q99595,Q9Y5Y5,O14925,Q99442,Q15388,O94826,O75381 19 +Mitochondrial membrane organization 0.5759153917690617 2.545369876777801 0.0109162040575436 1.0 0.7997756333143134 53 Q9NVH1,P50542,Q13505,Q9P0J0,Q8IWA4,Q9Y5J6,P62072,P05141,P17152,Q8N8Q8,O60313,Q9NS69,Q9Y584,Q16891,O75431,Q5HYI7,P45880,Q6UXV4,O14737,Q9Y5J9,Q15070,Q9BUR5,O95202,Q9H3K2,P52789,P12235,O94826,Q5XKP0,Q9Y512 29 +Sterol biosynthetic process 0.6262377735725619 2.525225582958434 0.0115624043257833 1.0 0.7997756333143134 27 Q15125,P48449,Q16850,Q14534,Q9H2C2,Q15800,O75845,P54646,Q6P1A2,Q14739,P16435,Q15392 12 +Mitochondrial cytochrome c oxidase assembly 0.8344578344099762 2.522438639656899 0.0116544280858665 1.0 0.7997756333143134 8 Q9P0S2,Q9Y2R0,Q15070 3 +Calcium ion import 0.7189016078256597 2.48467249294604 0.0129670669808523 1.0 0.7997756333143134 13 Q9H4I9,Q96AQ8,O75844,P16615,P21796 5 +Glycoprotein metabolic process 0.4850101368844022 2.460213734645258 0.0138854295382868 1.0 0.7997756333143134 72 Q9Y287,Q86SQ9,O60858,O15118,O60502,P35610,Q10472,Q9BXS4,Q9NQX7,Q8N4A0,Q8NCH0,Q7LGA3,Q9NRB3,Q9BV10,Q9H4A6,Q9HC07,Q99805,Q8NBI6,Q86YN1,Q96JB2,O43505 21 +Determination of adult lifespan 0.879257894361522 2.4570724818425367 0.0140074421892502 1.0 0.7997756333143134 6 O75844 1 +Carboxylic acid transport 0.6091413800820594 2.4438913428190316 0.0145298018217803 1.0 0.7997756333143134 33 O60831,P07602,Q96NB2,P30825,Q9NZJ7,Q9H2J7,Q9UBX3,Q9H2D1,Q9BQT8,Q9NP80,Q9Y619,P53985,Q15041 13 +Amyloid precursor protein metabolic process 0.6159904286541675 2.4429662005609623 0.014567101483657 1.0 0.7997756333143134 22 Q9Y287,O75298,P35610,Q9NQC3,O95197,P62942,Q9NQX7,Q15392 8 +Ph reduction 0.7201160078435479 2.426100401663389 0.0152620473559104 1.0 0.7997756333143134 12 Q8N511,O75503,Q93050,P50897,Q9Y487 5 +Establishment of protein localization to mitochondrial membrane 0.6129924932100752 2.423626703692547 0.0153663918357007 1.0 0.7997756333143134 20 P62072,Q8N8Q8,Q9NS69,Q9Y584,Q9Y512,Q9Y5J9,Q9Y5J6,Q15070 8 +Peptide catabolic process 0.7305336313736399 2.421417444719948 0.0154601121970476 1.0 0.7997756333143134 11 P42892,P55786,O14773,Q9NZ08,Q9UIQ6 5 +Intracellular protein transmembrane transport 0.6125221886931003 2.4212220298914855 0.0154684261787867 1.0 0.7997756333143134 24 Q9Y5Y5,O14925,O75298,O96008,P31751,Q99595,O95831,Q15629,O75381,O60830 10 +Chloride transport 0.7057295160980416 2.411408792099172 0.0158910259346538 1.0 0.7997756333143134 13 P51798,P54105,Q4KMQ2,Q9UHG3,P08183,Q9Y696,P30536,Q9C0H2,P51790 9 +Glycoside catabolic process 0.9076205287713852 2.4081372477797816 0.0160341519128148 1.0 0.7997756333143134 5 P04062,Q9BTY2,Q9NUJ1,P06280 4 +Phosphatidylglycerol metabolic process 0.7272688525677097 2.403994402641026 0.0162170215907964 1.0 0.7997756333143134 11 Q8WUK0,Q8NF37,O95674,Q8NCC3,Q9NP80 5 +Protein targeting to mitochondrion 0.5729654076876608 2.393191513189155 0.0167025202813104 1.0 0.7997756333143134 48 Q99797,P30536,P62072,Q9Y5J6,O60830,Q9NS69,Q9Y371,O96008,Q9Y584,O95831,Q8N4H5,Q10713,O00165,P51572,O14737,Q99595,P55786,Q9Y5J9,O14925,Q9Y512 20 +Phosphatidylethanolamine metabolic process 0.8630989421281967 2.387636948348637 0.0169570836944905 1.0 0.7997756333143134 6 Q9HBU6,Q8NCC3,Q9NP80,P35790,Q9UG56 5 +Endoplasmic reticulum membrane organization 0.7757706169020682 2.3702258910248326 0.0177772202927448 1.0 0.7997756333143134 9 Q8NHH9,Q15363,Q9NQC3,Q9P2W9,Q6P1A2,Q15041 6 +Ceramide biosynthetic process 0.7194029028460619 2.361866497481478 0.018183188926409 1.0 0.7997756333143134 11 P04062,P27544,O15269,Q96G23,Q13510 5 +Lipid localization 0.4592087478571747 2.350463603827857 0.0187500412765897 1.0 0.7997756333143134 75 O15118,P04062,O95674,P35610,O15260,P30536,P31751,P17900,Q9Y679,Q6P1A2,P23786,O14975,Q9NP80,P09455,Q9BQE5,Q8WTV0,Q99720,P07602,Q9H2V7,Q14534,O43772,Q9UJZ1,Q9BUR5,Q14108,Q9NZJ7,Q9H2C2,P08183,P11166,P35790 29 +Mitochondrial respiratory chain complex assembly 0.5789747708503535 2.343450850533829 0.0191062794172205 1.0 0.7997756333143134 43 O75306,O43676,P03886,O95139,Q9Y2R0,Q9H061,Q8N8Q8,Q6DKK2,Q86Y39,Q15070,Q9P0S2,Q9BSK2,Q9Y512,O95831,Q9NX14,Q9Y6M9,Q96CU9 17 +Regulation of blood pressure 0.6005437475913893 2.339333039836914 0.0193182040298038 1.0 0.7997756333143134 20 P09601,P42892,Q6RW13,P42785,P05023,Q9HB40,Q9NZ08,P20020,Q9UIQ6 9 +Steroid biosynthetic process 0.5685277724197382 2.3351549812564163 0.019535325957394 1.0 0.7997756333143134 47 Q15125,P48449,Q16850,Q53GQ0,Q14534,P05023,Q9H2C2,Q9H3P7,P30536,Q15800,O75845,P54646,Q6P1A2,Q14739,Q13510,P16435,Q15392 17 +Protein insertion into membrane 0.5939838710615846 2.333110015840113 0.0196423719221126 1.0 0.7997756333143134 33 Q8N4V1,Q9Y5J9,Q8N8Q8,Q9NPA0,Q9NS69,Q96A33,Q9Y584,P46379,Q15629,P62072,Q15070 11 +Purine nucleotide transport 0.7406136787011569 2.328042149709039 0.0199098656389193 1.0 0.7997756333143134 10 Q08722,P12236,O00400,Q8TB61,P12235,Q6NUK1,P33897,P05141 8 +Glycosphingolipid metabolic process 0.7669445492123619 2.3268619952040015 0.0199726115224185 1.0 0.7997756333143134 9 Q99805,P04062,Q16739,P17900,P06865,P06280 6 +Mitochondrial calcium ion transmembrane transport 0.7124383998663392 2.3243890084277763 0.0201046541363938 1.0 0.7997756333143134 11 O95202,Q9H4I9,Q96AQ8,Q8IYU8,P21796,Q9UJZ1 6 +Regulation of lysosomal lumen ph 0.8469272600036972 2.317572218289526 0.0204725815316992 1.0 0.7997756333143134 6 O75503,Q8N511,P50897 3 +Endoplasmic reticulum organization 0.5552814552119402 2.316212194561686 0.0205466856909832 1.0 0.7997756333143134 51 Q9BRK0,Q00765,Q9NPA0,P50542,Q15363,Q96A33,P57088,O95197,Q6P1A2,Q15629,Q8N4V1,Q5JRA6,Q8N5M9,Q9H6H4,Q9NQC3,Q6NUK4,Q9NVV0,O14657,Q9P2W9,Q12907,O43765,Q8NHH9,P61026,P46379,Q8NFQ8,Q15041 26 +Organic anion transport 0.5650015385672787 2.3062168493673356 0.0210985185565129 1.0 0.7997756333143134 47 Q8TB61,Q9Y619,Q9HC21,O00400,Q9NP80,Q9Y6M7,P07602,P30825,Q9H2J7,Q9BQT8,P53985,O60831,P12236,Q96NB2,Q9NZJ7,Q9UBX3,Q9H2D1,P12235,P11166,Q15041,O75915 21 +Lipoprotein metabolic process 0.5956726906940476 2.3061274676828845 0.0211035109199169 1.0 0.7997756333143134 20 Q9Y2B2,P04062,Q9H490,Q9BQE5,Q5HYI8,O43292,Q9NUJ1,P50897 8 +Glycoprotein biosynthetic process 0.5045152232575765 2.275352739011513 0.0228847780672598 1.0 0.7997756333143134 64 Q9Y287,Q86SQ9,O15118,O60502,P35610,Q10472,Q9BXS4,Q9NQX7,Q8N4A0,Q8NCH0,Q7LGA3,Q9NRB3,Q9BV10,Q9H4A6,Q9HC07,Q99805,Q8NBI6,Q86YN1,Q96JB2,O43505 20 +Macromolecule depalmitoylation 0.801164372520204 2.2359303383681284 0.0253563346506797 1.0 0.7997756333143134 7 Q9UMR5,P50897 2 +Amino acid transport 0.585268649644122 2.234782956173068 0.0254316013254531 1.0 0.7997756333143134 20 O60831,Q96NB2,P30825,Q96H78,Q9H2J7,Q9Y619,Q15041,O75915 8 +Secondary alcohol metabolic process 0.5580962198530762 2.229519239931807 0.0257793766140115 1.0 0.7997756333143134 46 Q15125,P48449,Q16850,O15118,Q14534,Q9H2C2,P04062,P35610,P49748,Q15800,Q9BQE5,Q8WTV0,O75845,Q6P1A2,Q14739,P16435,Q15392,P54646 18 +Oxidative phosphorylation 0.482065630139976 2.2240813769286163 0.0261429696286081 1.0 0.7997756333143134 68 O43676,P03886,O14949,P00846,O75306,O75208,O95139,O75964,P14406,Q99643,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9Y6M9,Q9BSK2,Q9UJZ1,P56385,O75251,Q9H3K2,P33897,P22695 23 +Protein transmembrane import into intracellular organelle 0.6476028329855258 2.2133351782649893 0.0268745460371799 1.0 0.7997756333143134 15 Q9Y5Y5,O14925,Q99595,O95831,O75381,O60830 6 +Peroxisome organization 0.6353538132757276 2.2130705336636027 0.0268927832290251 1.0 0.7997756333143134 16 P56589,Q9Y5Y5,O75192,Q7Z434,Q96HA9,O14734,P33897,O75381 8 +Multicellular organism aging 0.7432247460279119 2.209211198396015 0.0271599543440619 1.0 0.7997756333143134 9 O75844 1 +Vitamin transport 0.7934281785265632 2.2004633632517354 0.0277740365335885 1.0 0.7997756333143134 7 P38435,Q9H2D1,P04062,P11166,Q8WTV0 5 +Cristae formation 0.7407135574841773 2.1966605376428205 0.0280446992029699 1.0 0.7997756333143134 9 Q6UXV4,Q9NVH1,Q16891,Q5XKP0,Q9Y512,Q9BUR5 6 +Neutral lipid biosynthetic process 0.8166285454577042 2.184749244930439 0.0289072373208907 1.0 0.7997756333143134 6 Q8NCC3 1 +Ceramide transport 0.8497034581446545 2.16706618020408 0.0302298082324106 1.0 0.7997756333143134 5 P07602,P08183 2 +Calcium import into the mitochondrion 0.7585623067616927 2.164637197621509 0.0304154800221767 1.0 0.7997756333143134 8 Q96AQ8,Q9H4I9,P21796 3 +Ceramide catabolic process 0.8120187715964132 2.1643636796888837 0.0304364490140967 1.0 0.7997756333143134 6 Q13510,P04062,P06865,P06280 4 +Lysosomal lumen acidification 0.9206712782828432 2.160807731291011 0.0307101946127352 1.0 0.7997756333143134 4 Q8N511,P50897 2 +Sphingosine biosynthetic process 0.8481017955481726 2.1603062860591127 0.0307489666688829 1.0 0.7997756333143134 5 Q13510,P04062 2 +Glycoside metabolic process 0.7572910809871016 2.1585143571903895 0.0308878633795013 1.0 0.7997756333143134 8 P04062,Q9BTY2,Q9NUJ1,P06280 4 +Hormone biosynthetic process 0.7557455312305985 2.1510644637512746 0.0314711119023167 1.0 0.7997756333143134 8 P30536,P05023,Q53GQ0,P16435 4 +Amino acid transmembrane transport 0.6366402861189608 2.1472777820590303 0.0317711735432617 1.0 0.7997756333143134 15 O60831,Q96NB2,P30825,Q9H2J7,Q9Y619,Q15041 6 +Glycolipid catabolic process 0.8073079154563102 2.143482844408168 0.0320743471877211 1.0 0.7997756333143134 6 P04062,P04066,P06865,P06280 4 +Vitamin transmembrane transport 0.8054552143015405 2.1352574116807346 0.0327399896240332 1.0 0.7997756333143134 6 Q9H2D1,P04062,Q8WTV0 3 +Aminoglycan metabolic process 0.6440342471575544 2.123094031761047 0.0337459730471045 1.0 0.7997756333143134 14 Q8NCH0,Q7LGA3,P04066,P54802,O43505,P06865 6 +Transepithelial transport 0.8357263866500934 2.1079074852046773 0.0350389926427401 1.0 0.7997756333143134 5 P51798 1 +Proton transmembrane transport 0.5445480468885903 2.0997089564264377 0.03575445123672 1.0 0.7997756333143134 45 P21281,P00846,P05141,Q13423,O00400,P05023,O75964,Q9UHD1,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9UJZ1,P56385,O75251,P12235,Q96ES6,O75947,P51790 20 +Regulation of triglyceride metabolic process 0.9051347776104872 2.099502784536041 0.0357726026148521 1.0 0.7997756333143134 4 Q96N66,Q8WTV0 2 +Mitochondrion organization 0.479337427359704 2.0990723227073 0.0358105258204617 1.0 0.7997756333143134 204 O43676,Q96H55,Q99536,P03886,Q9H061,P27544,Q9P0S2,O60830,P21796,O95139,Q9Y6C9,Q9NS69,Q9Y371,Q9Y584,O75153,O75431,O95831,Q5HYI7,P45880,Q8N4H5,P51572,Q6UXV4,O14737,Q99595,O14548,P55786,Q9NX14,Q15070,Q9H300,O14925,O75251,Q9H3K2,Q96A26,Q5XKP0,Q8N2A8,Q9Y2R0,Q9NVH1,P04062,P50542,Q13505,P62072,Q96CU9,P05141,O95167,P17152,Q86Y39,Q9BWH2,Q16891,Q9GZT3,Q9NUQ9,P14406,Q10713,Q9Y241,Q16543,Q9BUR5,O95202,P52789,Q9H270,Q15388,Q13472,P12235,O94826,Q96HS1,Q9P0J0,Q8IWA4,Q5JRX3,O75306,Q9UDX5,Q8N8Q8,O60313,O75323,Q9H4A6,O94830,O43615,O43464,O00165,Q9Y5J9,Q9Y6M9,Q9BSK2,Q9UG56,Q99797,P30536,Q9NVI7,Q9BUB7,Q9Y5J6,Q9NX47,Q6DKK2,O96008,Q9UJZ1,Q9Y512,Q5T9A4 91 +Proton transporting two sector atpase complex assembly 0.7968678181510793 2.0970337638548218 0.035990586579206 1.0 0.7997756333143134 6 Q8N511,Q15070,Q92544 3 +Endoplasmic reticulum tubular network organization 0.6393343376946827 2.0952444889369053 0.0361492642988012 1.0 0.7997756333143134 14 Q9BRK0,Q9H6H4,Q8NHH9,P61026,Q9NQC3,P57088,O95197,Q15041 8 +Organic hydroxy compound metabolic process 0.4202954734086239 2.09208694952718 0.0364307383650708 1.0 0.7997756333143134 116 Q86SQ9,Q15125,P48449,Q16850,O15118,P04062,Q9Y4G8,P35610,P30837,Q6NUM9,Q6P1A2,Q15392,O15269,P49748,P51648,Q9BQE5,Q8WTV0,Q14739,Q13510,Q15800,P00374,Q10713,Q14534,O75845,P16435,P21964,P38435,Q9H2C2,Q14914,Q8NBN7,P54646 31 +Cotranslational protein targeting to membrane 0.6380341967743541 2.087525102902051 0.0368406943236037 1.0 0.7997756333143134 14 Q99442,P49458,P43307,Q9UHB9,Q15629,Q15041 6 +Vesicle targeting rough er to cis golgi 0.6690427682567242 2.087084100553705 0.0368805330165593 1.0 0.7997756333143134 11 Q9NR31,Q15363,P49755,O00743,Q9HCU5,O75340 6 +Inorganic anion transmembrane transport 0.7417337980911842 2.0832359392744704 0.0372297227006981 1.0 0.7997756333143134 8 P51798,Q9UBX3,Q4KMQ2,Q9UHG3,P51790 5 +Endoplasmic reticulum calcium ion homeostasis 0.7177982923414642 2.081290609865929 0.0374073141359503 1.0 0.7997756333143134 9 P55061,P51572,Q96A33,P16615,O76024 5 +Sphingoid metabolic process 0.7923282760090062 2.0767625418240723 0.0378234810355697 1.0 0.7997756333143134 6 Q13510,P04062,O15269 3 +Glycerolipid biosynthetic process 0.5299930300479294 2.0755997988234487 0.0379309800690077 1.0 0.7997756333143134 50 Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,O96017,Q9NX62,Q8TBX8,Q8WUK0,Q9NTJ5,Q8NCC3,Q8WTV0,O14735,Q9C0D9,O15228,Q96N66,Q9Y2B2,Q9BVG9,Q10713,Q92643,Q92604,P42356,O43292,P48651,P35790,Q9H490,Q9UG56 28 +Fatty acid transmembrane transport 0.7399249415978786 2.074441699987756 0.0380383079311434 1.0 0.7997756333143134 8 P23786,P11166,O43772,P31751,P33897 5 +Regulation of steroid metabolic process 0.6244967367840235 2.073526572603158 0.0381233007643295 1.0 0.7997756333143134 15 Q9H2C2,P05023,P49748,P30536,Q6P1A2,Q13510,P16435 7 +Mitochondrial protein processing 0.7913292000506619 2.07229516066927 0.0382379234601983 1.0 0.7997756333143134 6 Q99797,Q10713 2 +Terpenoid metabolic process 0.5742335949112961 2.065513661487662 0.0388744242614205 1.0 0.7997756333143134 19 P48449,Q9HB40,Q8NBN7,P51648,P09455 5 +Protein quality control for misfolded or incompletely synthesized proteins 0.6540105156060041 2.058066654922229 0.0395837353907044 1.0 0.7997756333143134 12 Q9BUN8,P46379,Q16740 3 +Maintenance of protein location in cell 0.5590255695069006 2.052266000755014 0.0401438183010793 1.0 0.7997756333143134 20 P52789,O43292,P30536,Q13438,O43731,Q9UH99,Q9H4A6,P24390 8 +Triglyceride metabolic process 0.6627188053309843 2.051956127174677 0.040173926368598 1.0 0.7997756333143134 11 Q96N66,Q9UBV2,Q92604,P50416,Q8WTV0,Q8NCG7 6 +Organic acid transport 0.5318481316905224 2.049295461510861 0.0404332321889115 1.0 0.7997756333143134 48 Q9Y619,P50416,P31751,P23786,O14975,Q9NP80,P09455,O43808,P30825,Q96H78,Q9H2J7,Q9BQT8,O43772,P53985,Q6P4A7,O60831,Q96NB2,Q9UBX3,Q9H2D1,P08183,P11166,P33897,Q15041,O75915 24 +Glycosyl compound catabolic process 0.6613819222099263 2.044512331776301 0.0409029604099999 1.0 0.7997756333143134 11 Q9BTY2,P04062,P04066,Q13126,P16260,Q9NUJ1,P06280 7 +Sulfur compound transport 0.6861764639976164 2.0432100409065748 0.0410316502022851 1.0 0.7997756333143134 10 O00400,Q70HW3,Q9UBX3 3 +Nucleotide transmembrane transport 0.7334584007237497 2.0429322941045593 0.0410591409272662 1.0 0.7997756333143134 8 P12236,Q8TB61,Q9H2D1,P12235,Q9BSK2,P05141 6 +Glucose import 0.6499736929775041 2.0350813141107955 0.0418426918283958 1.0 0.7997756333143134 12 Q99523,P31751,O75298,P52789 4 +Atp transport 0.782825140012447 2.0341813525398487 0.0419333139621833 1.0 0.7997756333143134 6 P12236,Q08722,P12235,Q6NUK1,P05141 5 +Glial cell proliferation 0.8121772404271365 2.0073843197034553 0.0447087571259059 1.0 0.7997756333143134 5 Q96G23,P04062 2 +Alcohol biosynthetic process 0.5406175679817566 2.0069695184077805 0.0447529087042872 1.0 0.7997756333143134 41 Q86SQ9,Q15125,P48449,Q16850,Q9H2C2,P04062,O15269,Q15800,O75845,P54646,Q6P1A2,Q14739,Q13510,P16435,Q15392,P00374 16 +Protein retention in er lumen 0.8071539657853581 1.9858053489115408 0.04705494161591 1.0 0.7997756333143134 5 P24390,Q13438,O43292,O43731 4 +Maintenance of protein localization in endoplasmic reticulum 0.8071539657853581 1.9858053489115408 0.04705494161591 1.0 0.7997756333143134 5 P24390,Q13438,O43292,O43731 4 +Dicarboxylic acid transport 0.6099952970393758 1.9846619194755457 0.0471820982695014 1.0 0.7997756333143134 15 O60831,Q9UBX3,Q9H2D1,Q9BQT8,Q15041 5 +Regulation of glycoprotein metabolic process 0.6195660070709431 1.9771570947219024 0.0480238757166866 1.0 0.7997756333143134 14 Q9Y287,Q99805,P35610,O14734,Q9BXS4,Q9UHD1,Q9NQX7 7 +Response to l glutamate 0.8045883503756479 1.97476570386334 0.0482947427473008 1.0 0.7997756333143134 5 O95831 1 +Protein import into mitochondrial matrix 0.6964240802693455 1.9723168313103492 0.0485734494038383 1.0 0.7997756333143134 9 O60830,Q99595 2 +Embryonic heart tube development 0.7440312650144838 1.9706078487595728 0.0487687481841034 1.0 0.7997756333143134 7 P42892,Q9ULK5 2 +Phospholipid transport 0.6382957134956823 1.9682578790249192 0.049038373731582 1.0 0.7997756333143134 12 Q14108,Q8WTV0 2 +Aerobic respiration 0.3925036277546658 1.966835867462282 0.0492021360799652 1.0 0.7997756333143134 93 O75306,O43676,Q13423,Q9H3K2,P03886,O75208,Q9Y6M9,Q7KZN9,Q9UDW1,O75964,P13073,P22695,O14949,P00846,Q15070,P14406,Q99643 17 +Very long chain fatty acid metabolic process 0.6271349522529787 1.9607767235801945 0.0499050744559708 1.0 0.7997756333143134 13 O14975,Q15067,Q9P035,P50542,Q9UKU0,Q9NZ01,P33897 7 +Aminoglycan biosynthetic process 0.7163228583255343 1.9589053824010645 0.0501238685868967 1.0 0.7997756333143134 8 Q8NCH0,Q7LGA3,O43505,P06865 4 +Negative regulation of calcium ion transmembrane transport 0.7157520258200382 1.9560930242724877 0.0504541967576452 1.0 0.7997756333143134 8 P21796,P78417 2 +Protein insertion into mitochondrial inner membrane 0.7405795746965542 1.9543292101083232 0.0506622965298557 1.0 0.7997756333143134 7 Q9Y584,P62072,Q9Y5J9 3 +Phosphatidic acid metabolic process 0.764595498359186 1.951953733808788 0.0509436978252202 1.0 0.7997756333143134 6 Q8NF37,Q9NPH0,Q9NUQ2 3 +Nadh dehydrogenase complex assembly 0.5450048302821582 1.951531982789385 0.0509937954558532 1.0 0.7997756333143134 30 O75306,O43676,P03886,Q9H061,Q15070,Q86Y39,Q96CU9 7 +Phosphatidylethanolamine biosynthetic process 0.8625621890547237 1.9296087301877296 0.0536553362895282 1.0 0.7997756333143134 4 Q9HBU6,P35790,Q9UG56 3 +Glycolipid biosynthetic process 0.6642973601921193 1.92610231026848 0.0540916002244562 1.0 0.7997756333143134 10 Q9Y2B2,Q99805,Q16739,O43292,Q8NBX0,Q9H490 6 +Double strand break repair via break induced replication 0.6861585286445591 1.9195162049354413 0.054919037461484 1.0 0.7997756333143134 9 P25205,Q9Y248,O75419,P49736,Q14566 5 +Signal peptide processing 0.7573307011553263 1.918987423938347 0.054985925440625 1.0 0.7997756333143134 6 O75503,Q15005,P67812,P61009 4 +Maintenance of protein localization in organelle 0.5973257122906841 1.9063208133142615 0.0566085954974657 1.0 0.7997756333143134 15 P52789,O43292,Q9UH99,Q13438,P30536,O43731,P24390 7 +Associative learning 0.6361461400385455 1.902842682966043 0.0570610758426741 1.0 0.7997756333143134 11 O00264,Q13641,P50897 3 +Iron ion homeostasis 0.5961358613310492 1.8989301215073753 0.0575736643022499 1.0 0.7997756333143134 15 O75027,Q8N511,P30519 3 +Sulfur amino acid biosynthetic process 0.7860530453106511 1.8946470526396408 0.0581391766994134 1.0 0.7997756333143134 5 Q13126 1 +Positive regulation of lipid catabolic process 0.7835283556404964 1.8836854390981632 0.0596075371640003 1.0 0.7997756333143134 5 Q8NCG7,P31751,P33897 3 +Lysosomal protein catabolic process 0.7247592315242557 1.8793628307124124 0.0601949679228859 1.0 0.7997756333143134 7 Q8N511,P04062 2 +Protein catabolic process in the vacuole 0.7247592315242557 1.8793628307124124 0.0601949679228859 1.0 0.7997756333143134 7 Q8N511,P04062 2 +Cellular response to biotic stimulus 0.5315522735993928 1.875049969020984 0.0607858494868314 1.0 0.7997756333143134 35 O75844,Q8IXJ6,Q86UE4,Q96A33,O43823,P30536,Q9NUQ9,Q8WTV0,P08670,O76024,Q9NZZ3 11 +Cellular respiration 0.3992149574558621 1.8745210601804716 0.0608586420944703 1.0 0.7997756333143134 110 O43676,P03886,P04062,Q9NZ45,O14949,P00846,O75306,Q13423,O75208,O75964,P14406,Q99643,Q7KZN9,Q9UDW1,P13073,Q9Y6M9,Q15070,Q9H3K2,P22695,Q16134 20 +Amyloid precursor protein catabolic process 0.5680613505169302 1.8605747738296152 0.0628042499652548 1.0 0.7997756333143134 17 O75298,Q9NQC3,Q16799,O95197,P62942,Q15392 6 +Nerve development 0.7430463486611802 1.853845557761836 0.063761258587528 1.0 0.7997756333143134 6 Q9H061 1 +Protein insertion into er membrane 0.5876803347800353 1.846245497279582 0.0648565675231653 1.0 0.7997756333143134 15 Q15629,Q8N4V1,Q9NPA0,P46379 4 +Regulation of hormone metabolic process 0.7746058855433507 1.8448544194165577 0.0650587186729043 1.0 0.7997756333143134 5 O75844,P16435 2 +Electron transport chain 0.4248319971279303 1.844346902100086 0.0651326002650676 1.0 0.7997756333143134 73 O75306,O43676,O75208,P03886,Q9H3K2,Q16134,P04062,Q7KZN9,Q9UDW1,P13073,O43175,O14949,Q9Y6M9,Q9Y6N1,Q99643 15 +Vesicle targeting to from or within golgi 0.6073360637005438 1.8436113114967048 0.0652398063432913 1.0 0.7997756333143134 13 Q9NR31,Q9Y6B6,Q15363,P49755,O00743,Q9HCU5,O75340 7 +Lipid catabolic process 0.3762660716218344 1.8376342184800312 0.0661163230207608 1.0 0.7997756333143134 85 Q8NHP8,P04062,O95470,P31751,Q8NCG7,P06865,P06280,P50897,Q9BWD1,P23786,Q8NCC3,P04066,Q9NP80,Q2T9J0,Q8WTV0,Q13510,Q8IXJ6,O15254,A1L0T0,Q16134,Q8N2A8 21 +Anatomical structure maturation 0.5299416834326349 1.8352988966421648 0.0664614144763795 1.0 0.7997756333143134 29 Q15125,Q8IXJ6,Q9Y2W6,P04062,O75503,Q8N2A8 6 +Positive regulation of erad pathway 0.7723172628304864 1.8348714065888223 0.0665247452223534 1.0 0.7997756333143134 5 Q4ZIN3,P46379,P51572,Q9UHD9 4 +Positive regulation of response to endoplasmic reticulum stress 0.6912428618495261 1.8345517343320872 0.0665721357162214 1.0 0.7997756333143134 8 O43765,Q4ZIN3,P51572,P46379,P57088,Q9UHD9 6 +Microtubule anchoring 0.6471799101682519 1.8334475157738823 0.0667360468857263 1.0 0.7997756333143134 10 O75381,Q15154,O95684 3 +Protein localization to endoplasmic reticulum 0.5242832281263808 1.8332702432050665 0.0667623923136038 1.0 0.7997756333143134 37 Q15005,Q99442,P51572,P49458,P61009,O43292,O15258,Q9NQC3,Q13438,O43731,P61026,Q9UGP8,Q9UHB9,Q15629,P46379,Q96HY6,P24390,Q9Y5M8 18 +Atp synthesis coupled proton transport 0.6135837429649968 1.8252512190387504 0.0679631277849905 1.0 0.7997756333143134 12 P24539,O75964,P00846,Q9UJZ1,P56385 5 +Mitochondrial atp synthesis coupled proton transport 0.6221911752321242 1.823569259634332 0.0682172174625748 1.0 0.7997756333143134 11 P24539,O75964,P00846,Q9UJZ1,P56385 5 +Negative regulation of glycoprotein metabolic process 0.7686498245901299 1.8188547764123868 0.0689335888798914 1.0 0.7997756333143134 5 Q9Y287,Q9BXS4 2 +Organic hydroxy compound biosynthetic process 0.4820400675039345 1.81728344778361 0.0691737231047322 1.0 0.7997756333143134 57 Q86SQ9,Q15125,P48449,Q16850,Q14534,Q9H2C2,P04062,Q9Y4G8,O15269,Q15800,O75845,P54646,Q6P1A2,Q14739,Q13510,P16435,Q15392,P00374 18 +Regulation of dna primase activity 0.7682463557520912 1.8170912899306648 0.0692031362257861 1.0 0.7997756333143134 5 Q9Y248 1 +Oligosaccharide metabolic process 0.733682508399876 1.810915390228813 0.0701539498649761 1.0 0.7997756333143134 6 P10253,P06280 2 +Iron ion transport 0.6429376177416396 1.810346538370603 0.0702420643098276 1.0 0.7997756333143134 10 Q8N4V1,O15173 2 +Regulation of steroid biosynthetic process 0.642324189744678 1.807001696124472 0.0707620147425318 1.0 0.7997756333143134 10 P05023,P30536,Q6P1A2,Q13510,P16435 5 +Glycerophospholipid catabolic process 0.6633701691584303 1.8012507325787794 0.0716633693480108 1.0 0.7997756333143134 9 Q8NCC3,Q8WTV0 2 +Negative regulation of blood pressure 0.8291021838993204 1.7942169275889974 0.072778551320868 1.0 0.7997756333143134 4 P42785 1 +Regulation of pattern recognition receptor signaling pathway 0.5348688283160874 1.793708966034878 0.0728596334765059 1.0 0.7997756333143134 19 Q9NQC3,Q9NPR9,O43657,Q86UT6 4 +Lipid homeostasis 0.5235036828577665 1.788840666714993 0.0736404795442124 1.0 0.7997756333143134 30 O15118,Q15067,Q5BJF2,Q9NP80,O15254,O15260,Q9NQC3,P09455,Q8WTV0,P54646,Q96CP7 11 +L amino acid transport 0.5979092862934543 1.7873224997694035 0.0738853795318408 1.0 0.7997756333143134 13 O60831,Q15041,Q9Y619,P30825 4 +Antigen processing and presentation of endogenous antigen 0.7053983197680203 1.7868399121383949 0.0739633664871646 1.0 0.7997756333143134 7 Q03518,Q9NZ08,P10321,P04439 4 +Antigen processing and presentation of endogenous peptide antigen 0.7053983197680203 1.7868399121383949 0.0739633664871646 1.0 0.7997756333143134 7 Q03518,Q9NZ08,P10321,P04439 4 +Peroxisome fission 0.7268843714264571 1.7796375385915144 0.0751352986574263 1.0 0.7997756333143134 6 Q96HA9 1 +Negative regulation of peptidyl tyrosine phosphorylation 0.7036417294688749 1.7784039439665131 0.0753375354055041 1.0 0.7997756333143134 7 O95684 1 +L alpha amino acid transmembrane transport 0.6054743188372744 1.7778568983738638 0.0754273607282709 1.0 0.7997756333143134 12 O60831,Q15041,Q9Y619,P30825 4 +Cell maturation 0.5214273977400861 1.7764962617970212 0.0756511575190008 1.0 0.7997756333143134 22 Q8IXJ6,Q9Y2W6,P04062,O75503,Q8N2A8 5 +Glycerophospholipid biosynthetic process 0.5076140226313897 1.775626694708769 0.075794467074739 1.0 0.7997756333143134 44 Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,O96017,Q9NX62,Q8TBX8,Q8WUK0,Q9NTJ5,O14735,Q9C0D9,O15228,Q96N66,Q9Y2B2,Q9BVG9,Q10713,Q92643,P42356,O43292,P48651,P35790,Q9H490,Q9UG56 25 +Estrogen metabolic process 0.7582935047007298 1.7735002495205785 0.0761458505793506 1.0 0.7997756333143134 5 O95470 1 +Cdp diacylglycerol metabolic process 0.7016745148160054 1.768948405747811 0.0769024851003779 1.0 0.8005530530225886 7 Q9NUQ2,O95674 2 +Methionine biosynthetic process 0.8220799686893348 1.7656081366835985 0.0774616139972752 1.0 0.8005530530225886 4 Q13126 1 +Negative regulation of protein tyrosine kinase activity 0.7234478494786032 1.7637914400249517 0.0777670992102619 1.0 0.8005530530225886 6 O95684 1 +Walking behavior 0.8196007126590854 1.7554922189317763 0.079175150445502 1.0 0.8005530530225886 4 O75844 1 +Granulocyte differentiation 0.6752431410535337 1.7543923576764853 0.0793632999444189 1.0 0.8005530530225886 8 Q8N5M9,Q14739 2 +Neuron recognition 0.7213166530970743 1.753952680349584 0.0794386156857203 1.0 0.8005530530225886 6 P35613,Q9NQC3,Q9Y639 3 +Smad protein signal transduction 0.632290129026096 1.7521296949535743 0.0797515092227214 1.0 0.801128832488869 10 O00400,Q96PK6,Q93062,P08670,Q9UIQ6 5 +Negative regulation of calcium ion transport 0.6303831769469646 1.741667750922984 0.0815665986267508 1.0 0.8015748338202732 10 P21796,P78417 2 +Amyloid precursor protein biosynthetic process 0.7180301956287817 1.7387633039680546 0.0820764058157881 1.0 0.8015748338202732 6 Q9Y287,Q9NQX7 2 +Endoplasmic reticulum unfolded protein response 0.516175931263783 1.738096699082656 0.0821937764503224 1.0 0.8015748338202732 22 Q9Y4P3,Q9BUN8,Q15363,Q7Z2K6,Q96HY6,P57088,O76024 7 +Protein depalmitoylation 0.748730273370861 1.7314576313834895 0.0833701753333033 1.0 0.8015748338202732 5 P50897 1 +Lipoprotein catabolic process 0.748730273370861 1.7314576313834895 0.0833701753333033 1.0 0.8015748338202732 5 P50897 1 +Chloride transmembrane transport 0.748300972506086 1.7295667509967934 0.0837077107810806 1.0 0.8015748338202732 5 P51798,Q9UHG3,P51790 3 +Regulation of lipoprotein metabolic process 0.8123053707978729 1.7256802486630451 0.084404953306957 1.0 0.8015748338202732 4 P04062 1 +Regulation of protein lipidation 0.8123053707978729 1.7256802486630451 0.084404953306957 1.0 0.8015748338202732 4 P04062 1 +Regulation of tor signaling 0.567941266426344 1.722156764131062 0.08504112460387 1.0 0.8015748338202732 15 O75844,Q9H4A6,P04062 3 +Atp synthesis coupled electron transport 0.5028790114825913 1.7221508485772956 0.0850421959189009 1.0 0.8015748338202732 43 O75306,O43676,O75208,P03886,Q9H3K2,Q7KZN9,Q9UDW1,P13073,O14949,Q99643 10 +O glycan processing 0.6680476299426861 1.7181386660727496 0.0857713256004941 1.0 0.8015748338202732 8 Q8N4A0,O43505,Q10472 3 +Positive regulation of mitochondrial calcium ion concentration 0.7129027377394969 1.715023692157282 0.0863408832576455 1.0 0.8015748338202732 6 Q96AQ8,Q8IYU8 2 +Phosphatidylcholine catabolic process 0.9465340379235258 1.7087743116882324 0.0874927628386861 1.0 0.8015748338202732 3 Q8NCC3,Q8WTV0 2 +Phosphatidylserine metabolic process 0.6888744724835019 1.7072193944107654 0.0877812815210987 1.0 0.8015748338202732 7 Q9BVG9,Q8NCC3 2 +Response to misfolded protein 0.623950886291572 1.7063007455182546 0.0879520993638942 1.0 0.8015748338202732 10 Q9BUN8,P46379 2 +Lipid biosynthetic process 0.4210125278456015 1.7032189151421708 0.0885271081607501 1.0 0.8015748338202732 158 Q86SQ9,Q15125,P48449,Q16850,Q9HBU6,Q8NF37,Q9P035,P04062,P27544,O95674,Q9H3P7,P35610,Q9NUQ2,P30536,O95470,Q9NPH0,Q6P1A2,Q8NCG7,Q96G23,Q15392,Q9NX62,Q8WUK0,Q53GQ0,O14975,P05023,Q8NCC3,Q16739,Q9UKU0,Q9NP80,O15269,P49748,Q9NZ01,P09455,Q8WTV0,Q9UHD1,Q14739,Q13510,Q8NBX0,Q15800,O14735,O15228,Q96N66,Q9C0D9,Q9BVG9,Q10713,Q9Y2B2,Q99805,Q14534,O95864,Q86YN1,P42356,O75845,O43292,P16435,Q9UBM7,Q9H7Z7,Q06136,Q9H2C2,O14734,P54646,P35790,Q9H490,Q9UG56 63 +Endoplasmic reticulum to golgi vesicle mediated transport 0.4248356740064881 1.6984682130449325 0.0894194271756494 1.0 0.8015748338202732 70 Q15363,O14653,O43264,P24390,O75340,Q5JRA6,Q9Y282,O95249,O43731,Q9Y6B6,Q9Y3B3,Q96RQ1,P51572,P49755,Q9P2W9,O00743,Q96PC5,Q9HCU5,Q12907,Q96JB2,Q9BVK6,Q9NR31,Q8NHH9,Q969X5,O95070,Q5BJH7 26 +Steroid hormone biosynthetic process 0.7085224922702986 1.6947041024747855 0.0901315670443376 1.0 0.8015748338202732 6 P30536,Q53GQ0 2 +Regulation of mitophagy 0.6833433346826425 1.6804374155993669 0.0928722414284606 1.0 0.8015748338202732 7 P21796,P27544,P12235 3 +Er associated misfolded protein catabolic process 0.6830024841790197 1.6787849205132854 0.093193968510461 1.0 0.8015748338202732 7 Q9BUN8,P46379 2 +Purine containing compound transmembrane transport 0.7048149450752708 1.6774771000465714 0.0934492238045643 1.0 0.8015748338202732 6 Q8TB61,P05141,P12236,P12235 4 +Acute inflammatory response 0.7037610749587384 1.6725756921474684 0.0944108554863829 1.0 0.8015748338202732 6 Q9BQE5 1 +Oocyte differentiation 0.6376974803164035 1.6663322721230818 0.0956472523118558 1.0 0.8015748338202732 9 Q9Y2W6,Q8N2A8 2 +Dna methylation 0.5586835504771717 1.663442674288456 0.096223856891938 1.0 0.8015748338202732 15 O75844,Q9Y2W6,Q8N2A8 3 +Tor signaling 0.5053220656770134 1.662558348991768 0.0964008743448359 1.0 0.8015748338202732 21 Q8NHS3,O75844,P04062,P54646,Q9H4A6,O75340 6 +Long chain fatty acyl coa metabolic process 0.6156230372596824 1.660335043485902 0.096847069659659 1.0 0.8015748338202732 10 Q53GQ0,Q9UKU0 2 +Neutrophil differentiation 0.7958817136223983 1.658328085889771 0.0972512630859874 1.0 0.8015748338202732 4 Q14739 1 +Response to increased oxygen levels 0.6133208389761664 1.6475935359505491 0.0994361077827863 1.0 0.8086563811304138 10 P00846,Q8N511 2 +Cytoplasm organization 0.930065618256858 1.6474861323461094 0.0994581643113494 1.0 0.8086563811304138 3 Q8N2A8 1 +Positive regulation of mitophagy 0.7932213930348223 1.64738871007273 0.0994781744381132 1.0 0.8086563811304138 4 P21796,P27544,P12235 3 +Regulation of membrane lipid distribution 0.6980829106049586 1.6461325042228 0.09973648168044 1.0 0.8086563811304138 6 Q96CP7,Q9H2C2 2 +Phospholipid metabolic process 0.3612969565858623 1.6441284399038905 0.1001496744980841 1.0 0.8086563811304138 84 Q86SQ9,Q9HBU6,Q8NF37,Q8NHP8,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,Q8WUK0,Q8NCC3,Q9NP80,O15269,Q8WTV0,O14735,Q9C0D9,Q96N66,Q9Y2B2,Q9BVG9,Q10713,Q86YN1,O43292,P35790,Q9H490,Q9UG56 24 +Respiratory electron transport chain 0.4662976169842677 1.640613595986835 0.1008776509047428 1.0 0.8086563811304138 56 O75306,O43676,O75208,P03886,Q9H3K2,P04062,Q7KZN9,Q9UDW1,P13073,O14949,Q16134,Q99643 12 +Long chain fatty acyl coa biosynthetic process 0.651665729659146 1.6351452838179792 0.1020185951688028 1.0 0.8129672514479355 8 Q53GQ0,Q9UKU0 2 +Ion transport 0.4466556279105615 1.631905131665205 0.1026994728294854 1.0 0.8129672514479355 209 Q9H0H5,Q70HW3,Q9HC21,Q8IYU8,P00846,P21796,Q8N4V1,Q08722,O75844,O00400,O75964,Q9C0H2,Q9UHD1,P45880,P07602,Q96ER9,P30825,O15173,O75027,O14548,Q9HD20,Q6P4A7,O75251,Q9UBX3,Q9UHG3,Q9H2D1,Q6NUK1,O75947,Q9BVC6,P55061,P05067,Q4KMQ2,Q8TB61,Q9Y619,P05141,P51798,Q13423,Q9H4I9,Q00325,Q9NW15,Q9NP80,P20020,O43808,Q9NVV0,Q9HC07,Q9BQT8,Q9UDW1,Q13546,P08195,P13073,P0CG08,P54105,P12235,P08183,Q96ES6,P78417,P62942,Q9Y277,Q9Y6M7,Q8NE01,O76024,Q7KZN9,Q9Y696,P16615,Q9NZJ7,P98194,P21281,Q96AQ8,P30536,Q15907,P27105,P05023,O96008,P24539,Q9H2J7,O43772,P53985,Q9UJZ1,P56385,O60831,P12236,Q96NB2,P11166,Q15041,O75915,P51790 86 +Early endosome to golgi transport 0.6724786425632894 1.6276470522755728 0.1035997460842572 1.0 0.8129672514479355 7 O15260,Q9Y5X2,O60499 3 +Diol biosynthetic process 0.6301022856196095 1.626090365935046 0.1039304331857771 1.0 0.8129672514479355 9 Q13510,P04062,P00374 3 +Diol metabolic process 0.6301022856196095 1.626090365935046 0.1039304331857771 1.0 0.8129672514479355 9 Q13510,P04062,P00374 3 +Regulation of phosphatidylcholine metabolic process 0.787841773925898 1.6252434217080456 0.1041107016335498 1.0 0.8129672514479355 4 Q8WTV0 1 +Fatty acid elongation 0.7866915422885546 1.620504388259811 0.1051239724407606 1.0 0.8129672514479355 4 Q9NZ01,Q9P035,P33897 3 +Ion homeostasis 0.3771422360587275 1.6179861237849698 0.1056655881460573 1.0 0.8129672514479355 106 P55061,P05067,P98194,Q96AQ8,P30519,Q96A33,Q92544,P30536,Q8IYU8,P62942,P50897,Q9H4I9,Q8N511,P05023,Q93050,Q16891,Q9Y6M7,Q9UHD1,Q8NE01,O76024,P20020,Q9Y487,P09601,Q9NVV0,Q15904,Q9HC07,P51572,Q9Y639,O75503,O75027,Q9Y696,O75787,P16615,Q9HD20,Q9Y6N1,Q9UJZ1,P0CG08,P33897,P78417,P51790 40 +Regulation of endoplasmic reticulum unfolded protein response 0.648068002853173 1.6168364210417867 0.1059135953584695 1.0 0.8129672514479355 8 Q07812,Q96HY6,Q92905,P57088,P18031,O76024 6 +Mitochondrial electron transport ubiquinol to cytochrome c 0.7855273116651976 1.6157062379345832 0.1061578416647859 1.0 0.8129672514479355 4 O14949 1 +Cell volume homeostasis 0.7223248529984079 1.6146110530431268 0.1063949503163139 1.0 0.8129672514479355 5 P54105,Q96ER9,P51790 3 +Positive regulation of protein exit from endoplasmic reticulum 0.7848258706467637 1.6128146907027492 0.1067847734853837 1.0 0.8129672514479355 4 Q9NR31,P51572,Q92544 3 +Lipoprotein localization 0.7848258706467625 1.612814690702744 0.1067847734853848 1.0 0.8129672514479355 4 O15260,Q5JRA6,A6NIH7 3 +Protein o linked glycosylation via serine 0.7846457532755764 1.612072109825207 0.1069462490155712 1.0 0.8129672514479355 4 Q8N4A0 1 +Cardiolipin metabolic process 0.6692667778025501 1.6119956547331438 0.106962885290794 1.0 0.8129672514479355 7 Q8WUK0,Q9NP80 2 +Outer mitochondrial membrane organization 0.7210676827194986 1.609021575217024 0.1076116240445159 1.0 0.8129672514479355 5 Q9NS69,Q9Y512 2 +Adp transport 0.782338308457709 1.6025560598200652 0.1090327013698551 1.0 0.8186092235321865 4 P05141,P12236,P12235 3 +Organic cation transport 0.7823383084577077 1.6025560598200592 0.1090327013698564 1.0 0.8186092235321865 4 Q9HC21,O43772,Q70HW3 3 +Dna replication checkpoint signaling 0.6443366831088273 1.5978173810732086 0.1100836252769636 1.0 0.8200783625789102 8 Q9Y619 1 +Mitotic dna replication 0.5746295446476046 1.5955744561195735 0.1105838343313616 1.0 0.8209508902036075 12 O75844,P25205,P49736,O75419 4 +Cellular iron ion homeostasis 0.5735237388026619 1.5889825494189456 0.112064332528869 1.0 0.8225144130736298 12 P09601,O75027,Q8N511,Q9Y487 4 +Er overload response 0.7164419109534461 1.588435542110621 0.1121878858253437 1.0 0.8225144130736298 5 Q96A33 1 +Phospholipid biosynthetic process 0.436445849635721 1.5837219257848694 0.1132570129948529 1.0 0.8229937787548335 64 Q86SQ9,Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,O96017,Q9NX62,Q8TBX8,Q8WUK0,Q9NTJ5,O15269,O14735,Q9UHD1,Q9C0D9,O15228,Q96N66,Q9Y2B2,Q9BVG9,Q10713,Q9NVV0,Q92643,Q86YN1,Q92604,P42356,O43292,P48651,P35790,Q9H490,Q9UG56 31 +Peptidyl glutamic acid modification 0.714909311413795 1.5816083696070604 0.1137390021637836 1.0 0.8235655480282662 5 Q8N0U8 1 +Regulation of mitochondrion organization 0.4719318892839578 1.5805789843082858 0.1139743341469796 1.0 0.8235655480282662 51 Q96H55,Q9NX47,Q99536,O00165,Q9H3K2,Q9Y6C9,P27544,O14737,Q96A26,P12235,P30536,Q9NUQ9,Q9H4A6,P21796,Q9UG56,Q8N2A8 16 +Regulation of ire1 mediated unfolded protein response 0.6817050404480477 1.5695430051306083 0.1165214670198881 1.0 0.8275995894561229 6 Q07812,Q96HY6,Q92905,P57088,P18031 5 +Glial cell migration 0.5774738823684693 1.5652724465782486 0.1175190408598056 1.0 0.8275995894561229 11 Q96N66,Q9NQC3,Q96G23 3 +Regulation of receptor signaling pathway via stat 0.6372018331476826 1.5613659730582194 0.1184374256117601 1.0 0.8275995894561229 8 Q9H490,Q9NX40 2 +Regulation of glial cell proliferation 0.7721869425926957 1.5606270946194636 0.1186117620532209 1.0 0.8275995894561229 4 Q96G23 1 +Proteoglycan biosynthetic process 0.6176315563140696 1.5597095494817712 0.1188285344361008 1.0 0.8275995894561229 9 Q8NCH0,Q7LGA3,Q99805 3 +Histone h4 k16 acetylation 0.7095398359415057 1.5576638144719004 0.1193129626389772 1.0 0.8275995894561229 5 O75844 1 +Embryonic heart tube morphogenesis 0.9060063187126656 1.5576411560083436 0.1193183367945778 1.0 0.8275995894561229 3 Q9ULK5 1 +Protein o linked glycosylation 0.5225377182625159 1.5569441977361962 0.1194837346764896 1.0 0.8275995894561229 17 Q8N4A0,O60502,O43505,Q10472 4 +Golgi ribbon formation 0.6774399198137947 1.5495235138490782 0.1212559234962542 1.0 0.8275995894561229 6 Q9H4A6,Q9Y3A6,O43752 3 +Positive regulation of actin cytoskeleton reorganization 0.7682272348521515 1.5442449934692817 0.1225289926539123 1.0 0.8275995894561229 4 Q9UQB8 1 +Cellular response to molecule of bacterial origin 0.4917384073699264 1.5437464198347093 0.1226497760204003 1.0 0.8275995894561229 27 Q8IXJ6,Q86UE4,O43823,P30536,Q8WTV0,P08670,Q9NUQ9,Q9NZZ3 8 +Response to food 0.706323753465578 1.5433035087327984 0.1227571527059527 1.0 0.8275995894561229 5 P80303,P53985 2 +Positive regulation of triglyceride metabolic process 0.901441725392821 1.5405611071107628 0.1234236398014225 1.0 0.8275995894561229 3 Q8WTV0 1 +Er nucleus signaling pathway 0.5474296474825563 1.533675380148248 0.1251095334948753 1.0 0.8275995894561229 14 Q15363,Q96A33,P16615,Q6P1A2,O76024 5 +Mitochondrial calcium ion homeostasis 0.5641568405054895 1.5329949841217452 0.1252770907816842 1.0 0.8275995894561229 12 O95202,Q9H4I9,Q96AQ8,P51572,Q8IYU8,Q16891 6 +Regulation of oxidoreductase activity 0.5287061445882675 1.5320554870895728 0.1255087428540604 1.0 0.8275995894561229 16 Q15070,P06280,Q8WTV0,P00374 4 +Response to oxygen levels 0.4466073316054204 1.52948595065459 0.1261440193343355 1.0 0.8279613356699744 59 O75306,Q9Y4P3,P00813,P52789,Q8IXJ6,Q8N511,Q96A26,P30519,Q92544,P11166,Q99757,P55786,O95831,P00846,Q9Y487 15 +Cytokine production involved in inflammatory response 0.6308259847762563 1.5287014315803424 0.1263384772580875 1.0 0.8279613356699744 8 P33897,Q53EL6,Q8IV08 3 +Fat soluble vitamin metabolic process 0.6719996353404896 1.5239458898094016 0.127522228681892 1.0 0.8317730617133067 6 P09455,P04062,Q8N0U8,P38435 4 +Axis specification 0.6101065318816784 1.5194775399285376 0.128642337294955 1.0 0.8333780322503984 9 Q9Y2W6,Q15363,Q8N2A8 3 +Protein targeting to membrane 0.484517116525523 1.5191316223719202 0.1287293684292172 1.0 0.8333780322503984 38 P56589,Q9Y5Y5,O60725,Q99442,O00560,Q5BJH7,P50542,P49458,P46379,P31751,P43307,Q9UHB9,Q15629,Q9UHD1,Q15041,P27105 16 +Positive regulation of carbohydrate metabolic process 0.7008458999159951 1.5188131416268216 0.1288095370456892 1.0 0.8333780322503984 5 P05067,P31751,P54646 3 +Anterior posterior axis specification 0.6282539675095832 1.5155010024745743 0.1296455766461521 1.0 0.8336212262700896 8 Q9Y2W6,Q15363,Q8N2A8 3 +Phosphatidylglycerol biosynthetic process 0.8942422053964938 1.5136030758441936 0.1301265405503451 1.0 0.8336212262700896 3 O95674 1 +Response to ph 0.6984771728188797 1.5082113401758452 0.1315004458318407 1.0 0.8369157741917893 5 P51798,Q15907,P04062 3 +Forebrain generation of neurons 0.6686340871504981 1.508099699624344 0.1315290120963952 1.0 0.8369157741917893 6 O14949 1 +Positive regulation of blood circulation 0.6981376328268492 1.5066910825317437 0.1318898583714305 1.0 0.8369157741917893 5 P00813,P16615 2 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.6259499147565883 1.5036646157238984 0.1326677444615223 1.0 0.8376043836419631 8 Q8N4V1 1 +Regulation of anion transport 0.5664495366432091 1.500658529363364 0.1334439044927458 1.0 0.8382287790885202 11 P55011,P14174,Q13546,P08183,Q15907,Q15041,O75915 7 +Sensory perception of light stimulus 0.5415788244384723 1.4969033188587937 0.1344184165317059 1.0 0.8407470030573218 14 Q9H6K4,O43924,O76024,P50897 4 +Regulation of amyloid precursor protein catabolic process 0.5324423378590082 1.4953307354546994 0.1348281474804944 1.0 0.8407470030573218 15 O75298,Q9NQC3,Q16799,O95197,P62942 5 +Very long chain fatty acid catabolic process 0.6942833302708278 1.4894240666965082 0.1363757350137802 1.0 0.845666786121463 5 O14975,Q15067 2 +Retinol metabolic process 0.6442350848690499 1.4893514924184634 0.1363948348780899 1.0 0.845666786121463 7 Q8NBN7 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4845511703996892 1.4889918172473593 0.1364895235021392 1.0 0.845666786121463 31 Q9Y282,Q96JB2,Q96RQ1,O43731,Q9P2W9,P24390 6 +Regulation of systemic arterial blood pressure 0.6042644871032452 1.4881558874819287 0.1367097875893128 1.0 0.845666786121463 9 P42785 1 +Regulation of glucose import 0.6040780433250507 1.4871550587121531 0.136973862548771 1.0 0.845666786121463 9 P31751,P52789 2 +Glycosaminoglycan catabolic process 0.7540422885572108 1.4854457208973744 0.1374257918262638 1.0 0.845666786121463 4 P54802,P04066,P16278 3 +Aminoglycan catabolic process 0.7540422885572108 1.4854457208973744 0.1374257918262638 1.0 0.845666786121463 4 P54802,P04066,P16278 3 +Negative regulation of developmental growth 0.6434102711369922 1.4852913336713232 0.1374666665846831 1.0 0.845666786121463 7 P49840,Q9NQC3,O94826,O60271 4 +Lipid droplet formation 0.753731343283579 1.484154946301279 0.1377678191045297 1.0 0.8459496743295335 4 Q14534,O95674,Q9Y679 3 +Adult locomotory behavior 0.52126972152377 1.482888496445107 0.1381040382798919 1.0 0.8472050210891462 16 O75844,P50897 2 +Modification of synaptic structure 0.6216391831493961 1.481491555479458 0.1384756335240449 1.0 0.8483933620705505 8 Q9UQB8 1 +Peroxisomal transport 0.6018031555908538 1.4749374872616077 0.1402293507104226 1.0 0.8561581155909849 9 P56589,Q9Y5Y5,P33897,O75381 4 +Neuron maturation 0.6605162803711002 1.4698089033260338 0.1416135171354873 1.0 0.8613370876670273 6 O75503,Q9NZJ7 2 +Antigen processing and presentation of exogenous peptide antigen 0.7493038039600536 1.4657677393995083 0.1427115726547692 1.0 0.8629683175028339 4 Q9UIQ6 1 +Oogenesis 0.5364075159198591 1.4643131032856114 0.14310841857104 1.0 0.8629683175028339 14 Q9Y2W6,Q8N2A8 2 +Phosphatidylcholine metabolic process 0.5276053199061297 1.4640875897850747 0.143170017676512 1.0 0.8629683175028339 15 Q96N66,Q8NF37,Q8NCC3,Q9NP80,Q8WTV0,P35790 6 +Sterol homeostasis 0.5362095804042506 1.4630640737770968 0.1434498472173111 1.0 0.8629683175028339 14 Q5BJF2,Q8WTV0,O15118 3 +Iron ion transmembrane transport 0.8803616730218713 1.4615752685128418 0.1438576356870387 1.0 0.8629683175028339 3 Q8N4V1 1 +Lipid import into cell 0.638444562928528 1.4608238153690551 0.1440637983494128 1.0 0.8629683175028339 7 P11166,P31751 2 +Protein import into peroxisome membrane 0.7480750598784016 1.4606623213789185 0.1441081341026286 1.0 0.8629683175028339 4 P56589,Q9Y5Y5 2 +Manganese ion transmembrane transport 0.880012433944661 1.4602654839139666 0.1442171243100474 1.0 0.8629683175028339 3 Q9HD20,Q9HC07 2 +Manganese ion transport 0.880012433944661 1.4602654839139666 0.1442171243100474 1.0 0.8629683175028339 3 Q9HD20,Q9HC07 2 +Synaptonemal complex organization 0.6877179279853709 1.459971670767915 0.1442978599028692 1.0 0.8629683175028339 5 P46379 1 +Carbohydrate derivative catabolic process 0.4786626357748878 1.4538734783503315 0.1459813870670068 1.0 0.8641200273108485 35 Q9BTY2,Q9H773,P04062,P04066,Q13126,O60502,P35610,P54802,P16260,Q9NUJ1,P06865,P06280 12 +Cerebellar cortex development 0.5584121067222892 1.45333952103431 0.1461295094191383 1.0 0.8641200273108485 11 P04062,O14949 2 +Eye photoreceptor cell differentiation 0.746268656716415 1.4531548049816472 0.1461807773171248 1.0 0.8641200273108485 4 Q8NBN7,P54802,Q15555 3 +Glycosylation 0.4513506986413967 1.4511233170853608 0.1467455247835256 1.0 0.8655293383791618 54 Q8N4A0,Q86SQ9,Q9HC07,Q96JB2,O15118,P04062,Q86YN1,O60502,O75503,O43505,Q10472,Q9BXS4,Q9BV10 13 +Fatty acyl coa metabolic process 0.506241244518082 1.4462554946676889 0.1481055536565787 1.0 0.8669932509295692 17 Q9UMR5,Q53GQ0,Q9UKU0,P50897 4 +Folic acid metabolic process 0.6141444032633354 1.4428568657916094 0.1490607961699894 1.0 0.8690096159185794 8 Q9H2D1 1 +Fatty acyl coa biosynthetic process 0.5411941764666227 1.442263795620956 0.1492279695091167 1.0 0.8690096159185794 13 Q9UMR5,Q53GQ0,Q9UKU0,P50897 4 +Oocyte construction 0.8740382945514908 1.437855619492594 0.1504750242498362 1.0 0.8737411600092923 3 Q8N2A8 1 +Srp dependent cotranslational protein targeting to membrane 0.5756261709004029 1.436983704543518 0.1507226238491277 1.0 0.8737411600092923 10 Q15629 1 +Regulation of defense response to virus 0.5140239638869992 1.4348023033664037 0.1513434413687939 1.0 0.8737411600092923 16 O43657,Q86UT6,Q7Z434,O75844,O94826 5 +Ire1 mediated unfolded protein response 0.6329800826570343 1.4338531025591013 0.1516141873607739 1.0 0.8737411600092923 7 Q07812,Q96HY6,Q92905,P57088,P18031 5 +Cerebellar purkinje cell layer development 0.6526192934763606 1.4324707380355772 0.1520091467395765 1.0 0.8741205763763307 6 P04062,O14949 2 +Negative regulation of amyloid precursor protein catabolic process 0.574486436912518 1.4305615092657955 0.1525559254966846 1.0 0.8749170785175606 10 Q16799,Q9NQC3,O75298,O95197 4 +Proteoglycan metabolic process 0.5732347582685875 1.4235051858801644 0.1545897598572159 1.0 0.8767809424506952 10 Q99805,Q8NCH0,Q7LGA3,Q9NRB3,Q9NX62 5 +Natural killer cell activation 0.6307195575332591 1.4226825196273245 0.1548282102310996 1.0 0.8769960912561581 7 P46379,Q5HYI8,Q96L92 3 +Glutamine metabolic process 0.529481653334724 1.4205401930918695 0.1554504758875203 1.0 0.8777206766328908 14 P49915 1 +Neuropeptide signaling pathway 0.8685990631763432 1.4174461151471085 0.156352538099622 1.0 0.881746024072342 3 Q9Y4G8 1 +Glycolipid transport 0.8684715681494579 1.416967661895557 0.1564923823747142 1.0 0.8817611974470092 3 P07602 1 +Pyramidal neuron differentiation 0.8683286358260185 1.41643127408007 0.1566492727639721 1.0 0.8818723070048832 3 O14949 1 +Retinoic acid metabolic process 0.8673806563534114 1.4128736838133 0.1576928680753997 1.0 0.8822029675857375 3 Q9HB40 1 +Negative regulation of tor signaling 0.6768273716951756 1.41101421617128 0.1582404222705191 1.0 0.8822029675857375 5 P49840,O75340,Q96B36,P54646 4 +Viral protein processing 0.5898389007340332 1.410506112052945 0.1583902929704073 1.0 0.8822029675857375 9 P48729,Q10472,P61009,P27824 4 +Adult behavior 0.4910661302265607 1.4092849128131797 0.1587509381774463 1.0 0.8828804338605558 18 O75844,P50897 2 +Cytosolic calcium ion transport 0.4735406141971126 1.4037007445220984 0.1604079806708407 1.0 0.8882540118284539 27 P55061,Q9H4I9,Q9NVV0,Q96AQ8,Q8IYU8,P16615,P78417,P62942,P21796,P20020 10 +Vitamin metabolic process 0.4734105187697978 1.4026944271631798 0.1607079798452897 1.0 0.889149399677597 27 Q96EY8,Q9Y5Z9,P38435,Q9H3L0,Q9H2D1,P04062,Q8N0U8,P11166,P09455,P78417,P00374 11 +Golgi vesicle budding 0.6746634116518055 1.4012723322077296 0.1611326515514695 1.0 0.8899671965845338 5 Q9H4A6,Q15363,P49755 3 +T cell differentiation in thymus 0.5688434802268495 1.398722296102595 0.1618962755080517 1.0 0.8910987951710363 10 Q5HYI8,O96005,P04062 3 +Membrane protein proteolysis 0.5415078606510038 1.3965768750951313 0.1625408482837795 1.0 0.8910987951710363 12 O43847,P38159,Q9NZ08,Q92542,Q9H300,Q16740 6 +Glutamate receptor signaling pathway 0.7314794625925074 1.3916122105868285 0.1640398592623286 1.0 0.8935821034731414 4 Q8NCG7,P05067 2 +Spinal cord development 0.5399833778020892 1.387345728919598 0.1653363652853556 1.0 0.8956012859942899 12 O43175,P25325,P07196 3 +Regulation of toll like receptor signaling pathway 0.5665425001197912 1.385719899712196 0.1658324493375613 1.0 0.8956012859942899 10 Q9NPR9 1 +Lipoprotein biosynthetic process 0.5236406347493907 1.3835174891057922 0.1665062485336867 1.0 0.8956012859942899 14 Q9Y2B2,P04062,Q5HYI8,O43292,Q9H490 5 +Negative regulation of blood circulation 0.8593465400497744 1.3827194341967437 0.1667509105506475 1.0 0.8956012859942899 3 P16615 1 +Cholesterol efflux 0.6218441263997321 1.3787519042631555 0.1679712602613872 1.0 0.8959929326385003 7 Q8WTV0,O15118 2 +Negative regulation of inflammatory response 0.5382282582403703 1.3767109208727226 0.1686016409505975 1.0 0.8959929326385003 12 Q86UT6,P00813,P28070,P04062,Q6P1A2 5 +Homologous chromosome segregation 0.5645659089433106 1.3745417876802206 0.1692735465175503 1.0 0.8959929326385003 10 P46379,Q9BTX1 2 +Mitochondrial electron transport cytochrome c to oxygen 0.6193321416364653 1.3662986147662894 0.1718452556283498 1.0 0.9015385229023778 7 P20674,P13073,Q7KZN9,O14548 4 +Vesicle targeting 0.4662027295482948 1.3661331077867742 0.171897188353028 1.0 0.9015385229023778 22 O95772,O00743,Q9NR31,Q15363,P49755,Q9Y6B6,Q9HCU5,O75340 8 +Protein processing involved in protein targeting to mitochondrion 0.8545437482321063 1.3646916259546795 0.1723499927194107 1.0 0.9015385229023778 3 Q10713 1 +Non canonical wnt signaling pathway 0.6381170379040759 1.3636960862558465 0.1726632363453433 1.0 0.9015385229023778 6 Q9ULK5 1 +Negative regulation of gliogenesis 0.7239562460700173 1.3602609250611717 0.1737473689174111 1.0 0.9052040800405482 4 Q8IXJ6,Q96G23 2 +Learning 0.4838894756516497 1.3587429212697304 0.17422806606685 1.0 0.9055070628486492 18 O00264,Q13641,P50897 3 +Fatty acid derivative biosynthetic process 0.502075440704484 1.3551452622481368 0.1753712803358076 1.0 0.9083213637011354 16 Q9UMR5,Q53GQ0,Q9UKU0,P50897 4 +Regulation of exit from mitosis 0.6362483492456223 1.3548166230322691 0.1754759890677881 1.0 0.9083213637011354 6 Q8IXJ6,P50748 2 +Embryonic axis specification 0.6164877858390255 1.352187680646439 0.17631528365261 1.0 0.9097359218319664 7 Q15363,Q8N2A8 2 +Embryonic pattern specification 0.6164877858390255 1.352187680646439 0.17631528365261 1.0 0.9097359218319664 7 Q15363,Q8N2A8 2 +Cobalamin metabolic process 0.849959239860157 1.3474834725508524 0.1778245728518861 1.0 0.9131263409463068 3 Q96EY8 1 +Regulation of response to endoplasmic reticulum stress 0.4642779571047137 1.3463332316544383 0.1781950731733257 1.0 0.9132801333566734 23 O43765,P55061,Q4ZIN3,O60313,P51572,P46379,Q92905,Q96HY6,P57088,Q9UHD9,Q6P1A2,P18031,O76024 13 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5948334660015944 1.3428622994669346 0.1793165659981941 1.0 0.9152043195140778 8 O43657,Q86UT6 2 +Nuclear pore organization 0.5251414260705992 1.3428310020866376 0.1793267023128009 1.0 0.9152043195140778 13 Q9NQC3,Q9BTX1,Q8NFH5 3 +Protein targeting to peroxisome 0.61431186359063 1.3413860154369803 0.1797951556301571 1.0 0.9152043195140778 7 P56589,Q9Y5Y5,O75381 3 +Cellular lipid catabolic process 0.3855989902040327 1.3364874406735356 0.1813900028700856 1.0 0.919527370168808 72 Q8NHP8,P04062,P31751,O95470,Q8NCG7,P06865,P50897,P06280,Q9BWD1,P23786,Q8NCC3,P04066,Q9NP80,Q2T9J0,Q8WTV0,Q13510,Q8IXJ6,O15254,A1L0T0,Q16134 20 +Import across plasma membrane 0.489612021579742 1.332375449779196 0.1827368452435147 1.0 0.9195713798845554 17 P30825,P05023,P11166,P31751,Q15041 5 +Lipopolysaccharide mediated signaling pathway 0.5914988491460711 1.3255363451369508 0.1849933229816054 1.0 0.9195713798845554 8 Q8WTV0 1 +Protein import into peroxisome matrix 0.7141955227314681 1.3195526536986912 0.1869844194245284 1.0 0.9195713798845554 4 Q9Y5Y5,O75381 2 +Phosphatidylinositol metabolic process 0.4603081068923981 1.316142784464269 0.1881261231488875 1.0 0.9195713798845554 23 Q96N66,Q9Y2B2,Q10713,Q92643,Q9NTJ5,O43292,Q92604,P42356,O14735,O96017,Q9H490,Q9NX62 12 +Heme transport 0.9751398384089496 1.313607909034288 0.1889781857746393 1.0 0.9195713798845554 2 O15173 1 +Iron coordination entity transport 0.9751398384089496 1.313607909034288 0.1889781857746393 1.0 0.9195713798845554 2 O15173 1 +Acylglycerol homeostasis 0.8408968655669712 1.31347289994147 0.1890236468549067 1.0 0.9195713798845554 3 Q8WTV0 1 +Protein import 0.339205159370562 1.3122251080917111 0.1894441925696002 1.0 0.9195713798845554 86 P56589,Q7Z434,P50542,O60830,Q7Z4Q2,Q9NS69,O96008,O95831,Q9UHD1,O14737,Q8NFH5,Q99595,Q8N1F7,Q53FT3,Q9Y5Y5,O14925,Q9BW27,Q9Y512,O75381 19 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.5270744953438636 1.3089582791939949 0.1905484834934212 1.0 0.9195713798845554 12 O43657,Q86UT6 2 +Regulation of cholesterol metabolic process 0.588247015669843 1.3086256228442676 0.190661197133019 1.0 0.9195713798845554 8 Q6P1A2,P49748,Q9H2C2,P16435 4 +Vasculogenesis 0.6076916648710476 1.3084877860119728 0.1907079146380494 1.0 0.9195713798845554 7 O95470 1 +Phosphatidylinositol biosynthetic process 0.4577626956759819 1.308448511129353 0.1907212277497927 1.0 0.9195713798845554 21 Q96N66,Q9Y2B2,Q10713,Q92643,Q9NTJ5,O43292,P42356,O14735,O96017,Q9H490,Q9NX62 11 +Amino acid import across plasma membrane 0.6250484515916616 1.3015255558411165 0.1930786227965399 1.0 0.9195713798845554 6 Q15041,O75915,P30825 3 +Photoreceptor cell development 0.7093936072180187 1.2995159679478026 0.1937669171525406 1.0 0.9195713798845554 4 Q8NBN7,P54802 2 +Amyloid beta formation 0.5324387284538561 1.2993348168055725 0.1938290507705879 1.0 0.9195713798845554 11 O75298,P49755,Q9NQC3,Q16799,O95197 5 +Mitochondrial proton transporting atp synthase complex assembly 0.8359961994031935 1.295086656331142 0.1952903375055728 1.0 0.9195713798845554 3 Q15070 1 +Phosphatidylcholine acyl chain remodeling 0.7082986652932681 1.294946531954026 0.1953386748817132 1.0 0.9195713798845554 4 Q96N66,Q8NF37 2 +Response to ischemia 0.5855223913376507 1.2944457994578842 0.1955114795017478 1.0 0.9195713798845554 8 O95831 1 +Amyloid beta metabolic process 0.5172506784688048 1.2937226906914494 0.1957612247256652 1.0 0.9195713798845554 13 O75298,P49755,Q9NQC3,Q16799,O95197 5 +Regulation of dna methylation 0.6046122927086055 1.2931687701909376 0.1959526942976048 1.0 0.9195713798845554 7 O75844 1 +Sodium ion homeostasis 0.6506998444790079 1.2931379769497189 0.1959633423930906 1.0 0.9195713798845554 5 P05026,P05023,P55011,Q9Y5X3 4 +Specification of symmetry 0.603986062375627 1.2900522515644024 0.1970325167329352 1.0 0.9195713798845554 7 Q9ULK5 1 +Regulation of release of cytochrome c from mitochondria 0.5165726264720336 1.2894963724124286 0.197225576668184 1.0 0.9195713798845554 13 O14737,Q96A26,Q9H3K2 3 +Negative regulation of amyloid precursor protein biosynthetic process 0.8314933041061503 1.2781979907208862 0.2011796244332915 1.0 0.9214061762044184 3 Q9Y287 1 +Homologous chromosome pairing at meiosis 0.5822928702207717 1.2776262571437358 0.2013812378462249 1.0 0.9214061762044184 8 P46379,Q9BTX1 2 +Protein o linked glycosylation via threonine 0.8312014816799002 1.2771036782016885 0.2015656464709596 1.0 0.9214061762044184 3 Q8N4A0 1 +Cation transport 0.3893657631757647 1.2730330668448242 0.2030063082846023 1.0 0.9227927224198604 158 P55061,P05067,P98194,P21281,Q96AQ8,Q4KMQ2,Q70HW3,Q9Y619,Q9HC21,P30536,Q8IYU8,P00846,P62942,Q15907,P21796,P05141,P27105,Q8N4V1,Q9H4I9,Q13423,Q00325,O75844,O00400,Q9NW15,P05023,O75964,Q9Y6M7,Q9UHD1,O76024,P20020,O43808,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,O15173,Q9UDW1,Q7KZN9,O75027,O43772,P13073,O14548,P16615,Q9HD20,Q9UJZ1,P56385,O75251,Q96NB2,P12235,Q96ES6,P78417,O75947,P51790 54 +Cell recognition 0.453492893842559 1.26989198727882 0.2041231077492293 1.0 0.9247032785831812 22 Q9NQC3,P45880,Q8WTV0 3 +Peripheral nervous system development 0.5460257946611728 1.2693312167351063 0.2043229570635665 1.0 0.9247032785831812 10 P51648,P31751,Q9NR77 3 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.5632343415521406 1.2663012485013756 0.2054052501466876 1.0 0.9273527761187184 9 P61978,P46379,O96017,Q9BVC6 4 +Regulation of phospholipid metabolic process 0.562672927286373 1.2632464930437766 0.2065006089142564 1.0 0.9275398272297608 9 Q8NF37,Q9UJZ1,Q8WTV0 3 +Glycosylceramide metabolic process 0.8274790177183599 1.2631471845476208 0.2065362894973077 1.0 0.9275398272297608 3 P04062,P06280 2 +Negative regulation of mrna catabolic process 0.4539840778707518 1.262897995464048 0.2066258404348135 1.0 0.9275398272297608 24 Q14103,P35637,Q14011,Q92804,O60506,Q13151,P98175 7 +Protein exit from endoplasmic reticulum 0.4520429252854641 1.258879094566195 0.2080740058719232 1.0 0.9291794720082852 22 Q9UBV2,Q9BUN8,Q9BVK6,P51572,Q9NR31,Q92544,O15260,Q13438,Q9Y679,Q9Y6B6,Q9HCU5 11 +Photoreceptor cell maintenance 0.8259247746347507 1.2573213843169708 0.2086372836147827 1.0 0.9291794720082852 3 P11166,P51790 2 +Eye photoreceptor cell development 0.8259247746347448 1.25732138431695 0.2086372836147902 1.0 0.9291794720082852 3 Q8NBN7,P54802 2 +Positive regulation of macroautophagy 0.4522571570668491 1.2496406535336568 0.2114308454239486 1.0 0.9291794720082852 24 P09601,O60858,P21796,P27544,Q9Y371,O15269,P12235,P54646,P05141,Q6UWE0 10 +Regulation of nitric oxide synthase activity 0.6141620445068143 1.249625233962826 0.2114364807495967 1.0 0.9291794720082852 6 Q8WTV0,P00374 2 +Photoreceptor cell differentiation 0.6409051111924545 1.248839261718051 0.2117238705653075 1.0 0.9291794720082852 5 Q8NBN7,P54802,Q15555 3 +Cellular response to oxygen levels 0.4542360576211727 1.2488073042377108 0.2117355617502159 1.0 0.9291794720082852 32 O75306,Q8IXJ6,Q8N511,Q96A26,P55786,O95831,Q9Y487 7 +Mucopolysaccharide metabolic process 0.5590621427376172 1.2435898928031044 0.2136505379347102 1.0 0.9330892019072632 9 Q8NCH0,O43505,Q9NRB3,Q9NX62 4 +Ornithine transport 0.9561839651957708 1.2432177959520183 0.2137875866245759 1.0 0.9330892019072632 2 P30825 1 +Dna methylation or demethylation 0.4490351340893834 1.2425268465876371 0.2140422415504967 1.0 0.9335668730855792 21 O75844,Q9Y2W6,Q8N2A8 3 +Postsynaptic cytoskeleton organization 0.6390328421308038 1.2403673082819453 0.2148395670967486 1.0 0.934636432014454 5 P07196,Q9Y6W5 2 +Dna methylation involved in gamete generation 0.8203294995337101 1.2363567039939674 0.216326002193977 1.0 0.9377626563474242 3 Q9Y2W6,Q8N2A8 2 +Regulation of epidermal growth factor activated receptor activity 0.6376275798176769 1.23400785813294 0.2171999760812968 1.0 0.9377626563474242 5 Q99816 1 +Negative regulation of nitric oxide metabolic process 0.818775256450101 1.2305357000234671 0.2184965669007503 1.0 0.938945819780819 3 P30536,P06280 2 +Regulation of erad pathway 0.5920086874919869 1.230375991144585 0.2185563396886096 1.0 0.938945819780819 7 Q4ZIN3,P46379,P51572,Q9UHD9 4 +Neuromuscular process 0.4494715509343226 1.2282373645123223 0.219357876125646 1.0 0.9405095439920184 24 P05067,O75844,P04062,P10253,P17900,P78417,O14773,P07196,Q6Y7W6 9 +Fucose metabolic process 0.8161475080153142 1.2206969306980635 0.2222007903116762 1.0 0.942358674651306 3 Q9BTY2 1 +Forebrain neuron development 0.8158158115220377 1.2194552568478896 0.2226714481955789 1.0 0.9430531887018292 3 O14949 1 +Forebrain neuron differentiation 0.8158158115220377 1.2194552568478896 0.2226714481955789 1.0 0.9430531887018292 3 O14949 1 +Mitochondrial fusion 0.4813377966336185 1.2159724203676388 0.2239954283090153 1.0 0.9461672855444544 16 Q07812,Q8NAN2,Q99536,O60313,Q9Y6C9,Q9GZY8,P02786,Q8IWA4,Q9H300,Q9UJZ1,Q8N2A8 11 +Mitochondrial respirasome assembly 0.8147342244326836 1.2154068582186652 0.2242109535854326 1.0 0.9463860304655722 3 Q9Y241,P14406 2 +Negative regulation of reactive oxygen species metabolic process 0.5181401821607091 1.2139570981829555 0.224764107264741 1.0 0.9471943178426736 11 O75027,P52789 2 +Regulation of nitric oxide metabolic process 0.5520510347315721 1.2053784487183328 0.2280572373394469 1.0 0.9487435173617575 9 P30536,Q08722,P06280 3 +Negative regulation of endoplasmic reticulum unfolded protein response 0.6312943672464881 1.205341580328408 0.2280714639871868 1.0 0.9487435173617575 5 Q96HY6,O76024,P18031 3 +Leukotriene metabolic process 0.6312349008604441 1.2050723825429024 0.2281753602663967 1.0 0.9487435173617575 5 Q14914 1 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6311666551599447 1.204763441229214 0.2282946370133207 1.0 0.9487435173617575 5 O43657 1 +Linoleic acid metabolic process 0.6859838322399869 1.2018127506076015 0.2294360842246625 1.0 0.9490585090256692 4 O95864,Q9NP80 2 +Integrated stress response signaling 0.6842380628821135 1.194529074624186 0.232271074536684 1.0 0.9490585090256692 4 Q15363 1 +Perk mediated unfolded protein response 0.6842380628821135 1.194529074624186 0.232271074536684 1.0 0.9490585090256692 4 Q15363 1 +Amino acid salvage 0.9428216283405784 1.1937911908854266 0.2325596583974643 1.0 0.9490585090256692 2 Q13126 1 +L methionine salvage from methylthioadenosine 0.9428216283405784 1.1937911908854266 0.2325596583974643 1.0 0.9490585090256692 2 Q13126 1 +Somatic diversification of immune receptors via somatic mutation 0.6286372068953299 1.193312548896516 0.2327469896629361 1.0 0.9490585090256692 5 Q9UQ84 1 +Neurotrophin signaling pathway 0.6018604080769704 1.1908923529146436 0.2336958469677033 1.0 0.9491033481714242 6 Q99523,Q96B36,Q9Y4G8 3 +Regulation of lipase activity 0.5140995530412663 1.1897698173935236 0.2341368756386717 1.0 0.949249913690414 11 P16435,P50897 2 +Endothelial cell proliferation 0.4918322949303213 1.1804588042789197 0.2378177858036303 1.0 0.9537944116576436 14 P09601,P57105,Q8WTV0,O75340 4 +Pirna metabolic process 0.9372280919825946 1.173158950600877 0.2407320700227475 1.0 0.9583074168273956 2 Q8N2A8 1 +Atp metabolic process 0.3511099698002087 1.1715345352161484 0.2413839845841228 1.0 0.9587898640025933 114 O43676,P21281,P03886,P30536,O14949,P00846,Q9NTK5,O75306,O75208,O95139,Q9BRR6,O75964,P14406,Q99643,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9Y6M9,Q9BSK2,P17858,Q9UJZ1,P56385,O75251,Q9H3K2,P52789,P33897,P22695,P54646,O75947 31 +Response to mitochondrial depolarisation 0.5795839205616857 1.1683617445746788 0.2426608791454749 1.0 0.9587898640025933 7 P04062 1 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5795839205616857 1.1683617445746788 0.2426608791454749 1.0 0.9587898640025933 7 P04062 1 +Regulation of camp dependent protein kinase activity 0.6230540533288282 1.1680365543428484 0.2427920203136135 1.0 0.9587898640025933 5 Q9Y4G8 1 +Regulation of mitochondrial fission 0.5102333919729352 1.166606048891509 0.2433694994365289 1.0 0.9592278426682422 11 Q9NUQ9,Q96H55,Q9NX47,Q96HS1 4 +Nervous system process 0.3335514484888738 1.1634916232967651 0.2446300948150641 1.0 0.9615922501423092 92 Q99797,O00264,Q9Y5J9,Q14108,O75844,Q9Y6M9,Q9H6K4,Q9Y639,P04062,P10253,Q13641,Q9UQB8,P78417,O14773,O76024,P62072,O43924,P50897 18 +Amino acid import 0.5442382994380635 1.162740218219185 0.2449349187122882 1.0 0.9615922501423092 9 Q15041,O75915,Q96NB2,P30825 4 +Intrinsic apoptotic signaling pathway in response to dna damage 0.4384451663887927 1.162253606036604 0.2451324657223477 1.0 0.9615922501423092 21 P09601,Q96K76,Q9BVC6,P61978,Q07820,P23396,P46379,O96017,O43464 9 +Prenylation 0.6748797441550268 1.1555021513476145 0.2478848521330414 1.0 0.9615922501423092 4 P49356,P49354 2 +Very low density lipoprotein particle assembly 0.7978098097659643 1.1521570976768103 0.2492565237290738 1.0 0.9615922501423092 3 P35610 1 +Sulfate transport 0.7977971942655062 1.152110031120105 0.2492758616014496 1.0 0.9615922501423092 3 Q9UBX3 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.5076986078537967 1.1514091444938737 0.2495639535579161 1.0 0.9615922501423092 11 Q03518,Q9Y6B6,Q9NZ08,P10321,Q9UIQ6 5 +Dendrite self avoidance 0.7959678483765811 1.1452864592102898 0.2520905132712294 1.0 0.9615922501423092 3 Q9Y639 1 +Positive regulation of fatty acid oxidation 0.7954616101958362 1.143398675524086 0.252873102154437 1.0 0.9615922501423092 3 P31751,P33897 2 +Positive regulation of fatty acid beta oxidation 0.7954616101958362 1.143398675524086 0.252873102154437 1.0 0.9615922501423092 3 P31751,P33897 2 +Vitamin d metabolic process 0.9288377874456146 1.142283908289018 0.2533360278045471 1.0 0.9615922501423092 2 P04062 1 +Metal ion homeostasis 0.3419829378627662 1.1389909160605374 0.2547069430425581 1.0 0.9615922501423092 79 P55061,P05067,P98194,Q96AQ8,P30519,Q96A33,Q8IYU8,P62942,Q9H4I9,Q8N511,P05023,Q16891,Q8NE01,O76024,P20020,Q9Y487,P09601,Q9NVV0,Q9HC07,P51572,Q9Y639,O75027,P16615,Q9HD20,Q9Y6N1,Q9UJZ1,P78417 27 +Sterol transport 0.4362621320926461 1.1386547744383038 0.254847172838732 1.0 0.9615922501423092 22 O15118,Q9H2C2,P35610,P30536,Q8WTV0 5 +Regulation of mitochondrial membrane permeability 0.4695385408865575 1.1363793493276226 0.2557978346195848 1.0 0.9615922501423092 16 P45880,P52789 2 +Mitochondrial adp transmembrane transport 0.7929748212620389 1.134128689358328 0.2567405709496482 1.0 0.9615922501423092 3 P12236,P12235 2 +Nucleobase transport 0.7929748212620285 1.134128689358289 0.2567405709496646 1.0 0.9615922501423092 3 Q9Y277,P12235 2 +Cellular response to increased oxygen levels 0.5727019410715042 1.1339830188793605 0.2568016711035463 1.0 0.9615922501423092 7 Q8N511 1 +Antigen processing and presentation of peptide antigen 0.498188421694706 1.1323853536444823 0.2574724597415931 1.0 0.9615922501423092 12 Q03518,Q9Y6B6,Q9NZ08,P10321,Q9UIQ6 5 +Response to testosterone 0.5543295821516578 1.1315682828960263 0.2578159808577014 1.0 0.9615922501423092 8 P04062,Q13126 2 +Regulation of hormone levels 0.3939085199489729 1.1307730494582788 0.2581506260424921 1.0 0.9615922501423092 64 P42892,Q53GQ0,O75844,Q8N5M9,P05023,Q9HB40,Q8NBN7,P30536,O95470,Q6NUM9,P09455,P53985,Q15907,P16435,P17858 15 +Synaptic transmission gabaergic 0.6689445069972637 1.130771562257804 0.2581512521589566 1.0 0.9615922501423092 4 Q13641 1 +Regulation of autophagy of mitochondrion 0.4511452304840881 1.1263074401139623 0.2600354096343895 1.0 0.9615922501423092 18 O00165,P27544,P12235,P30536,P21796,Q9H300 6 +Glycerolipid metabolic process 0.3643907021128737 1.1262983907737552 0.2600392387021479 1.0 0.9615922501423092 73 Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,Q8NCG7,Q8WUK0,Q8NCC3,Q9NP80,Q8WTV0,O14735,Q9C0D9,Q96N66,Q9Y2B2,Q9BVG9,Q10713,O43292,P35790,Q9H490,Q9UG56 21 +Regulation of anion transmembrane transport 0.588111671385829 1.125195809218607 0.2605060686116434 1.0 0.9615922501423092 6 Q15041,O75915,P08183 3 +Positive regulation of mitochondrion organization 0.436917645282265 1.1219258953351212 0.2618939493279142 1.0 0.9615922501423092 26 Q9NX47,Q96HS1,P21796,P27544,O14737,Q96A26,P12235,O94830,P05141,Q8N2A8 10 +Oligosaccharide lipid intermediate biosynthetic process 0.5358464119900376 1.1168904109823448 0.2640411850983595 1.0 0.9677088236199172 9 Q86SQ9,Q9BV10,Q86YN1 3 +Serine family amino acid biosynthetic process 0.5512561345804058 1.1154841494528376 0.2646430070920473 1.0 0.9677088236199172 8 O43175 1 +Import into cell 0.4360896524290196 1.1154636641581506 0.2646517809351927 1.0 0.9677088236199172 26 P30825,O14975,P05023,P11166,P08195,P31751,Q99816,Q15041,O75955,O75915,Q6UWE0 11 +Cellular copper ion homeostasis 0.6647738957630775 1.113406610693099 0.2655338371003779 1.0 0.9677534233097108 4 O60826,P05067 2 +Negative regulation of oxidoreductase activity 0.7868039340254156 1.1111511220741732 0.266503306072567 1.0 0.9700973451830212 3 Q15070 1 +Receptor recycling 0.5680729290901604 1.1108532763949983 0.2666315098747325 1.0 0.9700973451830212 7 P42892,Q9NZZ3 2 +Long chain fatty acid import across plasma membrane 0.7866977839510769 1.1107562054720266 0.2666733019584646 1.0 0.9700973451830212 3 P31751 1 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.4731439402267514 1.1080362939446171 0.2678461418343349 1.0 0.9712077356480352 15 P46379,O95831 2 +Positive regulation of cysteine type endopeptidase activity 0.4342891841191685 1.1060045208576956 0.2687245626147363 1.0 0.9712077356480352 25 Q9NR28,Q9NZJ7,P51572,O14737,Q96A26,Q9P0J0,P23396,Q12797,O95831,O75915,Q9BXK5,O75340 12 +Fatty acid derivative metabolic process 0.4341497810616014 1.104922067917238 0.2691933592666853 1.0 0.9712077356480352 25 Q53GQ0,Q9UKU0,Q14914,Q9NZ01,Q9UMR5,P50897 6 +Maternal process involved in female pregnancy 0.533385334107415 1.10343703630429 0.2698374204746678 1.0 0.9724129911612328 9 Q9BQE5 1 +Endochondral bone morphogenesis 0.6079332722270565 1.09960605916068 0.2715038008218124 1.0 0.9755234585591696 5 O75844,P16435 2 +Regulation of mitochondrial fusion 0.6078104076431691 1.0990503405391447 0.271746108785496 1.0 0.9755234585591696 5 Q99536,Q8N2A8 2 +Microtubule anchoring at microtubule organizing center 0.6608558355246827 1.0971046658137735 0.2725956408425016 1.0 0.9759580147753966 4 Q15154 1 +Microtubule anchoring at centrosome 0.6608558355246827 1.0971046658137735 0.2725956408425016 1.0 0.9759580147753966 4 Q15154 1 +Positive regulation of sequestering of calcium ion 0.6065902433968408 1.0935319191772093 0.2741603224202711 1.0 0.9759580147753966 5 P78417 1 +Negative regulation of ryanodine sensitive calcium release channel activity 0.6065902433968408 1.0935319191772093 0.2741603224202711 1.0 0.9759580147753966 5 P78417 1 +Regulation of the force of heart contraction 0.6586472238411665 1.0879207295388535 0.2766301039387657 1.0 0.9779716379742334 4 P10253,P16615 2 +Regulation of monooxygenase activity 0.5304099577817232 1.0871694000368084 0.2769619515377366 1.0 0.9779716379742334 9 P06280,Q8WTV0,P00374 3 +Response to oxidative stress 0.3381995815841684 1.0854418972998163 0.2777259844205613 1.0 0.9779716379742334 105 Q9NR28,P04062,Q8N0U8,P30519,O43169,P28074,Q15392,O75306,Q9NP80,Q99757,O95831,P00374,Q99720,Q8IXJ6,P16615,Q93062,Q7Z2K6,P54646,Q7LG56,Q16134 20 +Negative regulation of interleukin 6 production 0.7795019220821091 1.0840139438733367 0.2783586163983496 1.0 0.9779716379742334 3 P04062 1 +Negative regulation of cation channel activity 0.562630146474246 1.0836564674979992 0.2785171439726794 1.0 0.9779716379742334 7 P78417 1 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7781708524231554 1.0790738168583145 0.2805548222964882 1.0 0.9779716379742334 3 Q9UIQ6 1 +Central nervous system neuron development 0.5126487093467883 1.0787168768783584 0.2807139598123007 1.0 0.9779716379742334 10 O14949 1 +Maintenance of protein location in mitochondrion 0.777774198843622 1.077602096212651 0.2812113663468647 1.0 0.9780319784069472 3 P52789 1 +Glycosylceramide catabolic process 0.9111249223119886 1.0774372309510425 0.2812849787018892 1.0 0.9780319784069472 2 P04062 1 +Positive regulation of muscle contraction 0.5776143003369835 1.075038936153882 0.2823572964898289 1.0 0.9806996537726148 6 P00813,P78417 2 +Isoprenoid metabolic process 0.4315137135469918 1.0722288416287884 0.2836172589859149 1.0 0.9813038834679751 28 Q86SQ9,P48449,Q9HB40,Q8NBN7,P51648,P09455 6 +Response to endoplasmic reticulum stress 0.3223484629327856 1.0720439907009276 0.2837002738855232 1.0 0.9813038834679751 86 P55061,Q9H8Y8,O60858,Q4ZIN3,Q13217,Q15363,Q96A33,Q92575,P57088,Q9UHD9,Q9Y679,Q6P1A2,Q9Y4P3,O95831,O76024,Q9UBV2,P51572,Q9UBU6,Q96JB5,Q13438,P16615,P27824,Q9BUN8,Q9H3N1,P46379,Q7Z2K6,Q96HY6 27 +Lipophagy 0.6016540711980392 1.0712155552497369 0.2840725189414248 1.0 0.9813038834679751 5 Q9Y679 1 +Antiviral innate immune response 0.6015621463434732 1.0708001064410313 0.2842593190606741 1.0 0.9813038834679751 5 Q99623,Q92667,Q9NVI7 3 +Protein lipid complex subunit organization 0.576722216424101 1.0707779426976785 0.2842692869798262 1.0 0.9813038834679751 6 P35610,Q8WTV0 2 +Branched chain amino acid transport 0.7758781473422138 1.0705698015369762 0.2843629079018257 1.0 0.9813038834679751 3 Q96H78,Q9H2J7 2 +Peptidyl lysine dimethylation 0.7746347528753388 1.0659606345229984 0.2864414373214727 1.0 0.9839599492955808 3 Q03164,O15047 2 +Tetrapyrrole metabolic process 0.4235012814752881 1.0567073401730382 0.2906451740041862 1.0 0.9839599492955808 20 Q96EY8,O00264,Q7KZN9,P30519,O75027,P30536,Q9H3L0 7 +Potassium ion import across plasma membrane 0.5982352630622356 1.0557684416545063 0.291074019545221 1.0 0.9839599492955808 5 P05026,P05023,P55011 3 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.7718371153248362 1.0555974218208022 0.2911521793068279 1.0 0.9839599492955808 3 P51572,Q9UHD9 2 +Potassium ion homeostasis 0.6504975124378061 1.0540716161650203 0.2918501300805136 1.0 0.9839599492955808 4 P05026,P05023,P55011 3 +Cellular potassium ion homeostasis 0.6504975124378061 1.0540716161650203 0.2918501300805136 1.0 0.9839599492955808 4 P05026,P05023,P55011 3 +Cellular sodium ion homeostasis 0.6504975124378061 1.0540716161650203 0.2918501300805136 1.0 0.9839599492955808 4 P05026,P05023,P55011 3 +Dermatan sulfate biosynthetic process 0.904288377874445 1.0525479641941615 0.2925482167375151 1.0 0.9839599492955808 2 Q8NCH0 1 +Dermatan sulfate proteoglycan metabolic process 0.904288377874445 1.0525479641941615 0.2925482167375151 1.0 0.9839599492955808 2 Q8NCH0 1 +Dermatan sulfate metabolic process 0.904288377874445 1.0525479641941615 0.2925482167375151 1.0 0.9839599492955808 2 Q8NCH0 1 +Regulation of tube size 0.4910191144134531 1.0512662124387269 0.2931363404808729 1.0 0.9839599492955808 11 Q9HB40 1 +Nuclear pore complex assembly 0.5228075829933565 1.0455967823749317 0.2957472354763055 1.0 0.9847923206498672 9 Q9NQC3,Q9BTX1 2 +Lipid droplet organization 0.4900082502853566 1.045191849566216 0.29593430964439 1.0 0.9847923206498672 11 Q15042,Q14534,O95674,Q9Y679,O94830,O96017 6 +Olfactory behavior 0.9021131137352394 1.044646724346978 0.2961862761132825 1.0 0.9847923206498672 2 Q13641 1 +Chemosensory behavior 0.9021131137352394 1.044646724346978 0.2961862761132825 1.0 0.9847923206498672 2 Q13641 1 +Cholesterol storage 0.7688511172839679 1.04454822919752 0.2962318176136409 1.0 0.9847923206498672 3 Q8WTV0 1 +Regulation of autophagy 0.3306875169877863 1.0443786797600867 0.2963102236755126 1.0 0.9847923206498672 99 P21281,O60858,O15118,P04062,Q9NZ45,P30536,P10619,Q9BXS4,P21796,O75844,Q93050,Q9Y487,P07602,O00165,Q8IXJ6,Q9NZJ7,Q86UE4,P12235,P54646 19 +Membrane organization 0.4197254933170889 1.0380217443764446 0.299259931879194 1.0 0.9847923206498672 241 Q00765,P57088,Q15629,Q15392,P50897,Q8N4V1,O75844,Q9NS69,Q9Y371,Q16739,Q9Y584,O75431,Q5HYI7,Q9UHD1,P45880,O15228,Q6UXV4,O14737,P49755,P42356,Q9P2W9,O00743,Q96CP7,Q9HCU5,Q15070,Q8N1F7,Q9H3K2,Q9ULX6,Q9UQB8,O15258,P46379,P33897,Q5XKP0,Q86XL3,O15118,Q4KMQ2,Q9NVH1,Q15363,P50542,Q13505,P62072,P05141,O60499,O75340,Q5JRA6,P17152,Q9H6H4,O95249,Q6NUK4,Q16891,Q9Y6B6,P49354,O14657,Q9BUR5,O43765,O95202,P52789,Q9H270,Q9BVK6,Q9H2C2,Q8NHH9,P12235,P08183,O94826,Q9NZZ3,Q9NPA0,Q96A33,O43760,P31751,O43752,Q8N8Q8,Q9NQC3,Q9H4A6,Q8IXJ6,P16615,Q9Y5J9,Q9NZJ7,Q9UH99,P98194,Q9BRK0,P30536,O14653,Q6P1A2,Q9Y5J6,O14964,P50402,Q9NR31,Q9Y512,Q15041,P51790 90 +Vacuolar proton transporting v type atpase complex assembly 0.7669368363754453 1.0374713984415076 0.2995162185762465 1.0 0.9847923206498672 3 Q8N511 1 +Proton transporting v type atpase complex assembly 0.7669368363754453 1.0374713984415076 0.2995162185762465 1.0 0.9847923206498672 3 Q8N511 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4824653238407739 1.0358529844758864 0.3002707344531981 1.0 0.9847923206498672 12 Q9NR28,Q9NZJ7,Q96A26,O95831,Q9BXK5 5 +Establishment of protein localization to endoplasmic reticulum 0.4234167285360882 1.0335094041895128 0.3013655718689934 1.0 0.9847923206498672 23 Q15005,Q99442,P61009,P49458,P61026,P46379,Q9UGP8,Q9UHB9,Q15629,Q9Y5M8 10 +Ventricular system development 0.5518952226128007 1.0300333466621303 0.302994352004355 1.0 0.9847923206498672 7 Q96N66 1 +Negative regulation of cellular response to insulin stimulus 0.5680309948108415 1.029285594447931 0.3033454905964337 1.0 0.9847923206498672 6 P49840,Q8TBX8,P18031 3 +Peptidyl proline modification 0.4270359922567271 1.0289802896496585 0.3034889370697806 1.0 0.9847923206498672 32 Q9NWM8,Q8WUA2,P13674,Q9BV86,Q02790,O75718,Q9Y680,P26885,Q96AY3,P62942,Q5T1M5,Q32P28 12 +Glycosyl compound metabolic process 0.4266701070501013 1.0286142199440589 0.3036609931582947 1.0 0.9847923206498672 30 Q9BTY2,O60725,P04062,Q13126,P16260,Q9NUJ1,P06280 7 +Regulation of smooth muscle contraction 0.6440551910182309 1.0273649055005707 0.3042486702393414 1.0 0.9847923206498672 4 P00813 1 +Purine ribonucleoside metabolic process 0.5338703471316686 1.024480029427899 0.3056085987793193 1.0 0.9856361113807584 8 O60725,Q13126 2 +Stem cell proliferation 0.5029260003153876 1.0230512378739427 0.306283620530243 1.0 0.9856361113807584 10 P04062 1 +Intracellular lipid transport 0.4739920887648248 1.0226480583606468 0.3064742782641603 1.0 0.9856361113807584 13 O15118,P23786,Q9H2C2,O43772,P33897 5 +Copi coated vesicle budding 0.6427698578774439 1.02204265909587 0.3067607104512706 1.0 0.9856361113807584 4 Q15363,P49755 2 +Gpi anchor metabolic process 0.5494403509840154 1.017777753494333 0.3087835865515949 1.0 0.9865601707428916 7 Q9Y2B2,O43292,Q9H490 3 +Calcium ion import into sarcoplasmic reticulum 0.8940335612181352 1.0153807867471587 0.3099243480629443 1.0 0.9876245262662404 2 O75844 1 +Positive regulation of nitric oxide synthase activity 0.6404391485939189 1.012397369295437 0.3113480956853021 1.0 0.9891789856553732 4 Q8WTV0 1 +Negative regulation of leukocyte migration 0.5643323416419276 1.0116430479101763 0.3117087553347162 1.0 0.9896175743441432 6 P09601,P00813,Q5JRA6 3 +Positive regulation of mitochondrial translation 0.5305128022160867 1.0069121098931968 0.3139770119923459 1.0 0.990253692950864 8 Q9Y2R0 1 +Cellular lipid metabolic process 0.409930076711862 1.0064768826722374 0.3141862264804902 1.0 0.990253692950864 226 Q86SQ9,P48449,Q9HBU6,Q8NF37,Q8NHP8,P04062,O95674,Q9P035,P35610,Q9NUQ2,O95470,Q9NPH0,P31751,Q6NUM9,Q6P1A2,Q8NCG7,Q96G23,P06865,P50897,P06280,Q9BT22,Q9BWD1,Q53GQ0,Q8WUK0,O75844,P23786,Q8NCC3,P04066,Q9UKU0,Q9NP80,Q2T9J0,O15269,P49748,P51648,P09455,Q9NZ01,Q8WTV0,Q9BV10,O14735,Q13510,Q8NBX0,Q15800,Q9C0D9,Q96N66,Q9BVG9,P07602,Q10713,Q99805,Q8IXJ6,Q15067,O15254,Q86YN1,O43292,P16435,Q9H7Z7,Q9NZJ7,A1L0T0,Q9H2C2,Q9HB40,Q8N4Q0,Q14914,Q8NBN7,P54646,P35790,Q16134,Q9H490,Q9UG56 67 +Negative regulation of fat cell differentiation 0.5630975064430994 1.0057553939259425 0.314533249316008 1.0 0.990253692950864 6 Q8IXJ6,Q8N4Q0 2 +Positive regulation of protein kinase b signaling 0.4499152438086063 1.0036375327210274 0.3155533566704775 1.0 0.990253692950864 16 Q9NQC3,Q86UE4,Q13641 3 +Cartilage development involved in endochondral bone morphogenesis 0.6382134325155989 1.003193612018045 0.3157674545286264 1.0 0.990253692950864 4 O75844 1 +Sarcoplasmic reticulum calcium ion transport 0.5289553912678195 0.9987650919461374 0.3179085000606827 1.0 0.990253692950864 8 O75844,P78417 2 +Regulation of receptor recycling 0.5616191354641087 0.9987083777203802 0.3179359810972946 1.0 0.990253692950864 6 P42892 1 +Prostate gland growth 0.8887507768800373 0.9963189388965908 0.3190952046542223 1.0 0.990253692950864 2 P07602 1 +Neutral amino acid transport 0.5605897565083361 0.9938028175868449 0.3203188741429148 1.0 0.990253692950864 6 Q9H2J7,Q96NB2 2 +Keratan sulfate metabolic process 0.7538078955548584 0.9890889544212496 0.3226196213343044 1.0 0.990253692950864 3 O43505,P16278 2 +Regulation of protein tyrosine kinase activity 0.480623931451287 0.98879542115508 0.3227632449787143 1.0 0.990253692950864 11 Q99816,O95684 2 +Collagen fibril organization 0.5269068751123805 0.9880512880848042 0.3231275305729626 1.0 0.990253692950864 8 P13674,O75718,Q92791,Q96AY3 4 +Response to light intensity 0.8859540087010576 0.9862523310048148 0.3240093053533197 1.0 0.990253692950864 2 P31751 1 +Energy derivation by oxidation of organic compounds 0.351001196777696 0.9857904684817824 0.3242359439864162 1.0 0.990253692950864 132 O43676,P03886,P04062,Q9NZ45,P31751,O14949,P00846,O75306,Q13423,O75208,O75964,P14406,Q99643,Q7KZN9,Q9UDW1,P13073,Q9Y6M9,Q15070,Q9BSK2,Q9H3K2,P22695,Q16134 22 +Nerve growth factor signaling pathway 0.8856432566811694 0.9851349175996384 0.3245578038391201 1.0 0.990253692950864 2 Q9Y4G8 1 +Copii coated vesicle budding 0.4137236130770029 0.9825805717497414 0.325813910230798 1.0 0.990253692950864 20 Q5JRA6,Q9NR31,Q15363,P49755,O00743,Q9HCU5,O75340 7 +Protein deglycosylation 0.5817132464979247 0.9812682317168144 0.3264604844458718 1.0 0.990253692950864 5 O60858 1 +Negative regulation of defense response to virus 0.5415361992927775 0.9783464101896698 0.3279030233262354 1.0 0.990253692950864 7 O43657 1 +Multicellular organism growth 0.4173685144119782 0.9744509779548516 0.3298326683449011 1.0 0.990253692950864 25 P05067,O75844,P50542,Q15363,Q9Y696,P40763,O95470,Q14353,Q6Y7W6 9 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.6305116640337273 0.9714031715141372 0.3313475498363134 1.0 0.990253692950864 4 O14964,O75340 2 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6305116640337273 0.9714031715141372 0.3313475498363134 1.0 0.990253692950864 4 O14964,O75340 2 +Purine nucleoside metabolic process 0.4937630584447112 0.9706000024535848 0.3317475047531404 1.0 0.990253692950864 10 P16260,O60725,Q13126 3 +Divalent inorganic cation homeostasis 0.3975900494156072 0.9701274732542068 0.3319829563355818 1.0 0.990253692950864 56 P55061,P05067,P98194,Q96AQ8,Q96A33,Q8IYU8,P62942,Q9H4I9,Q16891,Q8NE01,O76024,P20020,Q9NVV0,Q9HC07,Q9Y639,P51572,P16615,Q9HD20,Q9UJZ1,P78417 20 +Ganglioside catabolic process 0.7485207769915168 0.9696884011245434 0.3322018337119234 1.0 0.990253692950864 3 P06865 1 +Ganglioside metabolic process 0.7485207769915168 0.9696884011245434 0.3322018337119234 1.0 0.990253692950864 3 P06865 1 +Fatty acid transport 0.4206543196443495 0.9685228936410726 0.3327832910740329 1.0 0.990253692950864 19 P23786,O14975,Q9NP80,O43772,P11166,P50416,P31751,P09455,P33897 9 +Intermembrane lipid transfer 0.5548585608730878 0.966511004589766 0.3337885430378908 1.0 0.990253692950864 6 P30536,P48739,P61916,Q9BZF1 4 +Segmentation 0.4768358016123643 0.9660342156905422 0.3340270601607773 1.0 0.990253692950864 11 Q15363,Q8N2A8 2 +Skeletal muscle contraction 0.7474504395426649 0.9657672725662776 0.3341606483885004 1.0 0.990253692950864 3 P78417 1 +Mitochondrial fission 0.451518664410082 0.9653969379008894 0.3343460346120748 1.0 0.990253692950864 15 Q96H55,Q9NX47,Q96HS1,Q9UDX5,O60313,Q9NUQ9 6 +Export across plasma membrane 0.5218548466826208 0.9616423366350356 0.3362292971242651 1.0 0.990253692950864 8 Q4KMQ2,P05023,P08183 3 +Negative regulation of protein secretion 0.5073145632102865 0.9609115758543704 0.3365966298728324 1.0 0.990253692950864 9 Q8N5M9,Q16850 2 +Antigen processing and presentation 0.4111813331710227 0.9547327196546036 0.3397128789384878 1.0 0.990253692950864 21 Q03518,P04062,P61026,Q9Y6B6,Q9NZ08,P10321,Q9UIQ6 7 +Phosphate ion transport 0.7441679910545115 0.9537561359331844 0.3402070975302074 1.0 0.990253692950864 3 Q9UBX3 1 +Phosphate ion transmembrane transport 0.7441679910545115 0.9537561359331844 0.3402070975302074 1.0 0.990253692950864 3 Q9UBX3 1 +Negative regulation of glial cell proliferation 0.8753884400248495 0.94838940371607 0.342931251809333 1.0 0.990253692950864 2 Q96G23 1 +Cellular metabolic compound salvage 0.5049947311276468 0.948243946334086 0.3430052795225169 1.0 0.990253692950864 9 Q9BV57,Q13126 2 +Pore complex assembly 0.4617742472773937 0.9458568609601172 0.3442215990304826 1.0 0.990253692950864 13 Q9NQC3,Q8N1F7,Q9BTX1 3 +Sulfur compound biosynthetic process 0.4099782283141234 0.943592335392731 0.3453780104609736 1.0 0.990253692950864 46 Q53GQ0,Q8TB61,Q8NCH0,Q9UKU0,Q13126,Q9NZ01,O43505,Q9UMR5,Q9BV57,P50897 10 +Endomembrane system organization 0.3818696685805433 0.9425670105090956 0.3459024204544809 1.0 0.990253692950864 184 Q9Y3A6,Q9H8Y8,Q86XL3,Q4KMQ2,Q9BRK0,Q00765,Q9NPA0,Q15363,P50542,A0FGR8,Q96A33,O15260,O43760,P57088,P31751,O95197,Q15629,P48729,Q6P1A2,O43264,O14964,Q8N4V1,O43752,Q5JRA6,O75844,Q8N5M9,Q9H6H4,Q16739,Q9Y371,Q6NUK4,Q9NQC3,Q9H4A6,Q9Y3B3,Q9NVV0,Q7RTS9,Q8IXJ6,O14657,P49755,Q7Z3D4,Q9P2W9,P16615,Q96CP7,Q8N1F7,Q12907,Q8TBA6,Q53FT3,O43765,P50402,Q14108,Q96JB2,Q9H270,Q9BVK6,Q9H2C2,Q9ULX6,Q8NHH9,Q9UQB8,P46379,P61026,Q9UH99,P33897,Q8NFQ8,Q99816,Q15041,Q9NZZ3,P51790 65 +Regulation of long term synaptic potentiation 0.5730185059582351 0.9421991525218572 0.3460906877372505 1.0 0.990253692950864 5 Q9Y639,P05067 2 +Protein targeting to lysosome 0.4671197950856421 0.941589177875493 0.3464030125551764 1.0 0.990253692950864 12 Q99523,O14964,Q14108,P13473 4 +Regulation of organic acid transport 0.503755869380754 0.9414811190309044 0.3464583605463569 1.0 0.990253692950864 9 P14174,P31751,Q15041,P55011,O75915 5 +Peripheral nervous system axon regeneration 0.6230473244779794 0.9406888811621664 0.346864318601455 1.0 0.990253692950864 4 P30536,Q96G23 2 +Regulation of programmed necrotic cell death 0.5177716267709858 0.9403149134123364 0.3470560520848846 1.0 0.990253692950864 8 Q13510 1 +Nucleobase catabolic process 0.5719776516936034 0.937530139437414 0.3484859278541297 1.0 0.990253692950864 5 P16260,Q02252 2 +Telencephalon glial cell migration 0.5485191203571884 0.9363700929685134 0.3490826706680243 1.0 0.990253692950864 6 Q96N66 1 +Cerebral cortex radially oriented cell migration 0.5485191203571884 0.9363700929685134 0.3490826706680243 1.0 0.990253692950864 6 Q96N66 1 +Cellular homeostasis 0.3550676020041908 0.935571895059896 0.3494936505916735 1.0 0.990253692950864 143 P55061,P05067,P98194,Q96AQ8,Q4KMQ2,Q96A33,P13473,Q92544,Q8IYU8,P62942,Q15907,P50897,Q9H4I9,P62995,Q8N5M9,Q8N511,P05023,Q9BWH2,Q93050,Q9NQC3,Q99757,Q16891,Q9Y6M7,Q9UHD1,O76024,P20020,Q9Y487,P09601,Q9NVV0,Q15904,Q96ER9,Q9HC07,P51572,Q9Y639,O75503,O75027,Q9Y696,O75787,P16615,Q9NWS0,Q9HD20,Q9UJZ1,P0CG08,P52789,P54105,P10253,P78417,P54646,P51790 49 +Positive regulation of heart rate 0.7389033497125821 0.9345375693095443 0.3500266658282163 1.0 0.990253692950864 3 P16615 1 +Protein localization to lysosome 0.4535396836912099 0.9341797357426084 0.3502111868843545 1.0 0.990253692950864 14 Q14108,P13473,Q99523,Q9NQC3,O14964 5 +Tail anchored membrane protein insertion into er membrane 0.4657198703164939 0.9329951333402212 0.3508224810927434 1.0 0.990253692950864 12 Q8N4V1,P46379 2 +Positive regulation of peptidase activity 0.4138900533455423 0.9310059030871828 0.3518505106297407 1.0 0.990253692950864 39 Q9NR28,P05067,P61289,Q9NZJ7,P51572,O14737,Q96A26,Q9P0J0,P23396,Q96HY6,P40763,Q9UL46,Q12797,O95831,Q92542,O75915,Q9BXK5,O75340 18 +Fatty acid alpha oxidation 0.5704022093516522 0.9304666512924398 0.3521295230367447 1.0 0.990253692950864 5 O14975,A1L0T0 2 +Histone h3 k9 acetylation 0.7375703278397159 0.9296807109444538 0.3525364244849536 1.0 0.990253692950864 3 Q03164 1 +Regulation of t cell differentiation in thymus 0.8701056556867623 0.9295631331610305 0.3525973230912567 1.0 0.990253692950864 2 O96005 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.736424467947179 0.9255088901770716 0.3547012614732021 1.0 0.990253692950864 3 P35610 1 +Natural killer cell mediated immunity 0.5007903774385567 0.925299410783816 0.3548101851690728 1.0 0.990253692950864 9 P68371,P46108,P07437,P11279,P51809,P04439 6 +Regulation of steroid hormone biosynthetic process 0.8676196395276576 0.9207294880438898 0.3571916766890364 1.0 0.990253692950864 2 P16435 1 +Regulation of hormone biosynthetic process 0.8676196395276576 0.9207294880438898 0.3571916766890364 1.0 0.990253692950864 2 P16435 1 +Positive regulation of striated muscle contraction 0.867619639527654 0.9207294880438766 0.3571916766890433 1.0 0.990253692950864 2 P78417 1 +Positive regulation of monooxygenase activity 0.5451408416923771 0.9203319728648056 0.3573993057970004 1.0 0.990253692950864 6 Q8WTV0,P00374 2 +Second messenger mediated signaling 0.4093918595134698 0.9186864371420618 0.3582596059284164 1.0 0.990253692950864 24 P00813,O75844,Q9Y4G8,P16615,P63096,P78417,Q9UHD1 7 +Negative regulation of cytokine production involved in inflammatory response 0.7345005941255649 0.9185110864969532 0.3583513574857178 1.0 0.990253692950864 3 Q53EL6 1 +Membrane raft organization 0.4990559595462639 0.9158400592620848 0.359750789170818 1.0 0.990253692950864 9 P50897 1 +N terminal protein amino acid modification 0.4841066066144742 0.9153808348411536 0.3599917360342801 1.0 0.990253692950864 10 Q86UY6,Q9BV86 2 +Response to acid chemical 0.4069071344515979 0.9140219100282384 0.3607053330660492 1.0 0.990253692950864 22 Q99729,Q14103,P55061,Q15388,Q9UQB8,O94826,O95831 7 +Vacuole organization 0.3916631787267883 0.9113320111059234 0.3621204647609799 1.0 0.990253692950864 56 Q9HC07,Q14108,Q8N511,P04062,O75503,P54802,P16615,P11117,O14773,P50897 10 +Pigment metabolic process 0.4116041695833463 0.9110081570076104 0.3622910757908035 1.0 0.990253692950864 29 Q7KZN9,Q9Y4G8,P30519,O75027,P30536,P49915,O00264 7 +Methionine metabolic process 0.565752335963031 0.9096453714967674 0.3630095625515217 1.0 0.990253692950864 5 Q13126 1 +Regulation of camp mediated signaling 0.8638906152889994 0.9075111230701502 0.3641365701285539 1.0 0.990253692950864 2 Q9Y4G8 1 +Neuron projection regeneration 0.4669348998275052 0.906587960861688 0.3646247305893009 1.0 0.990253692950864 11 P07196,P00374,Q96G23,P30536 4 +Multicellular organismal movement 0.5271030353422654 0.9065157744812732 0.3646629193746062 1.0 0.990253692950864 7 P10253,P78417 2 +Regulation of er to golgi vesicle mediated transport 0.5413244884455983 0.9022369179358852 0.3669310274391852 1.0 0.990253692950864 6 Q9NR31,Q9HCU5,Q9P2W9 3 +Pyridine containing compound metabolic process 0.5403844534877214 0.8977837805454639 0.3693008333445549 1.0 0.990253692950864 6 Q13126 1 +Detection of biotic stimulus 0.5400999439087166 0.8964363256475342 0.3700197735855437 1.0 0.990253692950864 6 Q8WTV0 1 +Regulation of actin cytoskeleton reorganization 0.4948314454931491 0.8928169591438014 0.3719552028332058 1.0 0.990253692950864 9 Q9UQB8 1 +Histone h3 k4 monomethylation 0.8592293349906696 0.8910442503350516 0.372905431421465 1.0 0.990253692950864 2 Q03164 1 +Histone h3 k4 dimethylation 0.8592293349906696 0.8910442503350516 0.372905431421465 1.0 0.990253692950864 2 Q03164 1 +Reactive nitrogen species metabolic process 0.4402249428957263 0.8909403033606843 0.3729611969514235 1.0 0.990253692950864 15 Q08722,P30536,O43169,P16435,P06280 5 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.6107117680894966 0.8901759055822962 0.3733714401206711 1.0 0.990253692950864 4 Q7LG56 1 +Glycerophospholipid metabolic process 0.3741270503999198 0.8889422283087197 0.374034128993892 1.0 0.990253692950864 63 Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,Q8WUK0,Q8NCC3,Q9NP80,Q8WTV0,O14735,Q9C0D9,Q96N66,Q9Y2B2,Q9BVG9,Q10713,O43292,P35790,Q9H490,Q9UG56 20 +Atp biosynthetic process 0.4012541727669285 0.8880648783491841 0.3745058535807672 1.0 0.990253692950864 20 P00846,P24539,Q9UJZ1,O75964 4 +Aspartate family amino acid biosynthetic process 0.4786929319966989 0.8844690001665327 0.3764430896065507 1.0 0.990253692950864 10 Q13126 1 +Tripartite regional subdivision 0.6091020350386919 0.8836096343921083 0.3769069763935722 1.0 0.990253692950864 4 Q8N2A8 1 +Blastoderm segmentation 0.6091020350386919 0.8836096343921083 0.3769069763935722 1.0 0.990253692950864 4 Q8N2A8 1 +Adipose tissue development 0.4785081728194895 0.883414783007206 0.3770122064403032 1.0 0.990253692950864 10 P43490,O15173 2 +Cell cycle dna replication initiation 0.5362439172073441 0.8781894961499567 0.3798408912866011 1.0 0.990253692950864 6 P25205 1 +Leukotriene biosynthetic process 0.7224121852657717 0.8747423810431277 0.3817140945531112 1.0 0.990253692950864 3 P09960,O14880 2 +Calcium ion transport 0.3839935101633991 0.8739501069713772 0.3821454253673535 1.0 0.990253692950864 58 P55061,Q9H4I9,P98194,Q9NVV0,Q9HC07,Q96AQ8,Q4KMQ2,O75844,P30536,Q8IYU8,P08195,O76024,P16615,P78417,P62942,P21796,Q9UJZ1,P20020 18 +Epithelial cell differentiation involved in prostate gland development 0.7218635075619962 0.8727644885413712 0.3827914592471968 1.0 0.990253692950864 3 P07602 1 +Regulation of protein glycosylation 0.7211687907988484 0.8702612913863546 0.3841576276055582 1.0 0.990253692950864 3 Q9UHD1,Q9BXS4 2 +Response to ether 0.6058033195417211 0.8701739305609741 0.3842053602847672 1.0 0.990253692950864 4 Q9H4A6 1 +L glutamate transmembrane transport 0.5195834633138845 0.8692193870913082 0.3847271453146257 1.0 0.990253692950864 7 O60831,Q15041,O75915 3 +Lipid modification 0.3873115878922785 0.8681427074134815 0.3853162138093347 1.0 0.990253692950864 56 P04062,P50542,P35610,P50416,P31751,Q6P1A2,Q9BWD1,P23786,O14975,Q9NTJ5,Q2T9J0,P49748,Q709F0,Q96N66,Q10713,Q15067,O15254,P16435,A1L0T0,O14734,P33897,Q16134 22 +Cellular amino acid biosynthetic process 0.4065230694028547 0.8672728325581668 0.3857925384354184 1.0 0.990253692950864 30 Q9BV57,O43175,P00374,Q13126 4 +Negative regulation of calcium ion transport into cytosol 0.5339073856517922 0.8671478251190133 0.3858610193453111 1.0 0.990253692950864 6 P62942,P78417 2 +Regulation of multicellular organism growth 0.4428270382340797 0.8653336718616585 0.3868556746094476 1.0 0.990253692950864 14 P05067,O75844,P50542,P40763,O95470,Q14353 6 +Histone h3 deacetylation 0.5552079351843957 0.8625948621215397 0.3883602562282306 1.0 0.990253692950864 5 Q9H4L7,Q8IXJ6 2 +Brown fat cell differentiation 0.5179008784687514 0.8608889475449183 0.3892992095011292 1.0 0.990253692950864 7 Q02252,O75192 2 +Glycolytic process through fructose 6 phosphate 0.5022878874887223 0.8596443708250651 0.3899851082601027 1.0 0.990253692950864 8 Q9BRR6,P52789 2 +Sensory perception 0.4059919793369337 0.8583093632690886 0.3907216605487815 1.0 0.990253692950864 32 Q99797,Q14108,Q9Y6M9,Q9H6K4,O43924,Q9Y5J9,P62072,O76024,P50897 9 +Developmental maturation 0.405258500539631 0.8574775264946181 0.3911810297723768 1.0 0.990253692950864 39 Q15125,Q9NZJ7,Q8IXJ6,Q9Y2W6,P04062,O75503,P07196,Q8N2A8 8 +Retina morphogenesis in camera type eye 0.5538049296608951 0.856353843448738 0.3918020870988523 1.0 0.990253692950864 5 Q8NBN7,P54802 2 +Positive regulation of jnk cascade 0.5167236564991062 0.8550641338843922 0.392515643883816 1.0 0.990253692950864 7 O00560,P05067,Q13546 3 +Triglyceride catabolic process 0.7169213117878781 0.8549851466858451 0.3925593706702051 1.0 0.990253692950864 3 Q8NCG7 1 +Cellular response to glucose starvation 0.4580583832831373 0.8533900269418744 0.3934430502131629 1.0 0.990253692950864 11 Q9Y4P3,P11166,P54646 3 +Ubiquinone metabolic process 0.5157522535857745 0.850259996791382 0.3951805518615603 1.0 0.990253692950864 7 Q8NI60,O75208 2 +Protein hydroxylation 0.446201774696241 0.8481567689498122 0.3963506696168073 1.0 0.990253692950864 13 P13674,Q92791,O75718,Q96AY3,Q12797,Q32P28 6 +Body morphogenesis 0.4863907591472886 0.8469042725920136 0.3970484808049899 1.0 0.990253692950864 9 O75787,Q7Z460,O95470,Q12797 4 +Cellular response to hydrogen peroxide 0.4193435469231249 0.8453379884624177 0.3979221566596345 1.0 0.990253692950864 17 O95831 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.8455562461155801 0.8431265600591267 0.3991576658258373 1.0 0.990253692950864 2 O75844 1 +Mitochondrial electron transport nadh to ubiquinone 0.4018692536542599 0.8425409601041085 0.399485222521128 1.0 0.990253692950864 27 O75306,O43676,O75208,P03886 4 +Amine transport 0.5285949174978192 0.8420885676387598 0.399738379977772 1.0 0.990253692950864 6 P55011,Q15041,O14656,O75915 4 +Head morphogenesis 0.5280451540890526 0.8394991526445433 0.4011892645019075 1.0 0.990253692950864 6 O95470,Q12797 2 +Histone h4 k20 methylation 0.7121541809138912 0.8379001982617239 0.4020867574174787 1.0 0.990253692950864 3 Q14166,O96028 2 +Calcium mediated signaling 0.4105748357187437 0.8365630477772741 0.4028382237098333 1.0 0.990253692950864 18 P00813,O75844,P51572,P16615,P78417,Q9UHD1 6 +Regulation of gliogenesis 0.4498449250829789 0.8357103167997527 0.4033178899247116 1.0 0.990253692950864 12 Q8IXJ6,Q96G23 2 +Bone growth 0.7105093330256026 0.8320205608115784 0.4053973390551699 1.0 0.990253692950864 3 O75844 1 +Growth plate cartilage development 0.7105093330256026 0.8320205608115784 0.4053973390551699 1.0 0.990253692950864 3 O75844 1 +Connective tissue development 0.3989791443976629 0.8315044384469196 0.4056887219214873 1.0 0.990253692950864 25 O75844,O15173,P35610,Q96HY6,P16435,P43490 6 +Polyol biosynthetic process 0.4435281798725266 0.8314226426412609 0.4057349121746059 1.0 0.990253692950864 13 Q13510,P04062,P00374 3 +Negative regulation of organic acid transport 0.842137973896824 0.8312429810946103 0.4058363784325762 1.0 0.990253692950864 2 P31751 1 +Negative regulation of atp dependent activity 0.525993996444763 0.829844848322151 0.4066265103506241 1.0 0.990253692950864 6 Q15070 1 +Retrograde transport endosome to golgi 0.4021242599517462 0.8243408863495613 0.4097458930658155 1.0 0.990253692950864 35 Q8NBN3,O75503,O15260,O95249,O60499 5 +Positive regulation of oxidoreductase activity 0.4952358878453648 0.823050184233665 0.4104794557718931 1.0 0.990253692950864 8 Q8WTV0,P00374 2 +Cardiac epithelial to mesenchymal transition 0.8396519577377233 0.822625876159408 0.4107207789961944 1.0 0.990253692950864 2 Q9NQC3 1 +Regulation of establishment of protein localization to mitochondrion 0.4159529529081106 0.8218531080034016 0.41116050368516 1.0 0.990253692950864 17 O00165,Q9H270,O14737,Q9Y371,P55786,O43464,Q9H300 7 +Fat cell differentiation 0.3990228958194838 0.8202010024137942 0.412101530622873 1.0 0.990253692950864 27 O75192,Q8IXJ6,Q8N4Q0,Q99523,P31751,Q9NZ08 6 +Negative regulation of lipid biosynthetic process 0.5234825920808318 0.8180393236552056 0.4133347335435822 1.0 0.990253692950864 6 Q8NF37,P05023 2 +Response to dexamethasone 0.481055600033962 0.8179589071374523 0.4133806519923682 1.0 0.990253692950864 9 P04062 1 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5927296958871328 0.8172163605172152 0.4138047945108076 1.0 0.990253692950864 4 Q7L576,Q9Y6W5 2 +Positive regulation of actin nucleation 0.5927296958871328 0.8172163605172152 0.4138047945108076 1.0 0.990253692950864 4 Q7L576,Q9Y6W5 2 +Hyperosmotic salinity response 0.5926342329763827 0.8168315216008482 0.4140247157399446 1.0 0.990253692950864 4 O95202 1 +Cellular response to salt stress 0.5926342329763827 0.8168315216008482 0.4140247157399446 1.0 0.990253692950864 4 O95202 1 +Cellular hyperosmotic salinity response 0.5926342329763827 0.8168315216008482 0.4140247157399446 1.0 0.990253692950864 4 O95202 1 +Pyrimidine containing compound transmembrane transport 0.8362336855189579 0.8108133710998561 0.4174728546427366 1.0 0.990253692950864 2 Q9BSK2 1 +Quaternary ammonium group transport 0.8362336855189572 0.8108133710998522 0.4174728546427388 1.0 0.990253692950864 2 O43772 1 +Azole transmembrane transport 0.8362336855189365 0.8108133710997818 0.4174728546427793 1.0 0.990253692950864 2 P30825 1 +Regulation of vasoconstriction 0.7033687016584796 0.8065916101529749 0.4199018089979058 1.0 0.990253692950864 3 P42892 1 +Organic hydroxy compound catabolic process 0.4449777307410766 0.8059764239158792 0.4202564431605258 1.0 0.990253692950864 12 P30837,Q10713,Q8WTV0,P21964 4 +Behavior 0.3502849784092777 0.8032309848084233 0.4218412396551572 1.0 0.990253692950864 69 P05067,O00264,O15118,P04062,P30536,P17900,Q15154,P50897,O75844,Q13641,O76024,Q9Y639,O43815,P53985,Q6Y7W6,P10253,P54802,O75915,P51790 19 +Response to camp 0.4782303276576125 0.8026586212257201 0.422172075689363 1.0 0.990253692950864 9 P35613,P05067,Q9Y4G8 3 +Macrophage differentiation 0.5415282166423815 0.8019695491801487 0.422570572910784 1.0 0.990253692950864 5 P05067,P04062 2 +Phosphatidylinositol 3 kinase signaling 0.4442757170620924 0.8016926362859169 0.4227307764442616 1.0 0.990253692950864 12 Q10713,O00165 2 +Establishment of pigment granule localization 0.7018961765620133 0.8013677846651961 0.4229187595006323 1.0 0.990253692950864 3 Q15907,P62820 2 +Negative regulation of receptor binding 0.8328154133001882 0.7990436885663579 0.4242650797702767 1.0 0.990253692950864 2 P16615 1 +Ribonucleoside metabolic process 0.4768239218827188 0.7950501248975329 0.4265843451795135 1.0 0.990253692950864 9 Q13126 1 +Cardiac muscle cell proliferation 0.5185320199278998 0.7948196515291139 0.4267184180183587 1.0 0.990253692950864 6 Q8NDZ4,P10644 2 +Membrane repolarization 0.5041087860630187 0.7928579291302412 0.4278606011259984 1.0 0.990253692950864 7 O75844 1 +Positive regulation of autophagy 0.3981484522350031 0.7915106883172427 0.428646041516439 1.0 0.990253692950864 35 O60858,P27544,Q9Y371,O15269,Q86UE4,P12235,Q9BXS4,P54646,P21796,P19474 10 +Aspartate family amino acid metabolic process 0.3884064030084397 0.7909355996779054 0.4289815730006583 1.0 0.990253692950864 20 Q9BV57,O43175,Q13126 3 +Dolichyl diphosphate biosynthetic process 0.698613588972302 0.789748448981424 0.4296746906201671 1.0 0.990253692950864 3 Q86YN1 1 +Rna stabilization 0.3941849983758156 0.7880127140231639 0.4306892691094839 1.0 0.990253692950864 26 P35637,Q14011,Q92804,O60506,Q13151,P98175 6 +Cardiac muscle cell membrane repolarization 0.5170644334056275 0.7879502475468376 0.4307258081493486 1.0 0.990253692950864 6 O75844 1 +Neuron projection maintenance 0.6979508560511953 0.787406972896877 0.4310436661802153 1.0 0.990253692950864 3 P33897 1 +Protein kinase b signaling 0.3923252237403895 0.7869176434325935 0.4313300784877962 1.0 0.990253692950864 24 O00165,Q9NQC3,Q86UE4,Q13641 4 +Pigment biosynthetic process 0.3930414455864434 0.7854805923000643 0.4321718449006204 1.0 0.990253692950864 25 Q7KZN9,Q9Y4G8,O75027,P30536,P49915,O00264 6 +Lipid storage 0.4105736439958025 0.7846565245417895 0.4326549793960001 1.0 0.990253692950864 17 Q14534,P04062,O95674,P35610,Q9Y679,Q8WTV0 6 +Regulation of alcohol biosynthetic process 0.5373329911987892 0.7834888418587987 0.4333401035647994 1.0 0.990253692950864 5 Q6P1A2,P16435 2 +Regulation of cholesterol biosynthetic process 0.5373329911987892 0.7834888418587987 0.4333401035647994 1.0 0.990253692950864 5 Q6P1A2,P16435 2 +Glycosphingolipid biosynthetic process 0.8272218769421847 0.7798798593009714 0.4354615945088027 1.0 0.990253692950864 2 Q99805 1 +Glucosylceramide metabolic process 0.8272218769421824 0.7798798593009635 0.4354615945088074 1.0 0.990253692950864 2 P04062 1 +Posttranslational protein targeting to membrane translocation 0.5828597024600968 0.777585855721398 0.4368132021218835 1.0 0.990253692950864 4 Q99442 1 +Long chain fatty acid transport 0.4164018673985776 0.7772942608777668 0.4369851802730748 1.0 0.990253692950864 16 P23786,O14975,Q9NP80,O43772,P11166,P31751,P33897 7 +Lung alveolus development 0.5824632864269809 0.7760011368412396 0.4377483146246161 1.0 0.990253692950864 4 P00813 1 +Regulation of protein targeting 0.3907784717343004 0.7750122765189893 0.4383324053926212 1.0 0.990253692950864 24 O00165,O14737,Q9Y371,P31751,P55786,Q9UHD1,P27105 7 +Retinal rod cell differentiation 0.8256681168427458 0.7745782702662676 0.4385889015612993 1.0 0.990253692950864 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.8256681168427458 0.7745782702662676 0.4385889015612993 1.0 0.990253692950864 2 P54802 1 +Retinal rod cell development 0.8256681168427458 0.7745782702662676 0.4385889015612993 1.0 0.990253692950864 2 P54802 1 +Negative regulation of release of cytochrome c from mitochondria 0.5000720201629615 0.7730456994131147 0.4394953353750752 1.0 0.990253692950864 7 Q9H300,Q9H3K2 2 +Positive regulation of chemokine production 0.4993156613582548 0.769339259451124 0.4416919367409073 1.0 0.990253692950864 7 P09601,P05067,Q7Z434 3 +Response to muramyl dipeptide 0.5806983824863274 0.7689526356220214 0.4419214287254147 1.0 0.990253692950864 4 Q9NZZ3 1 +Peptidyl lysine hydroxylation 0.5340126268724434 0.7689038290479235 0.4419504041589928 1.0 0.990253692950864 5 Q92791,O60568,Q96AY3 3 +Lipid metabolic process 0.4246238213176063 0.7679907083047234 0.4424927051338403 1.0 0.990253692950864 297 Q15125,Q9HBU6,Q9H6K4,Q15392,P50897,Q9BWD1,O75844,Q8NCC3,Q9UKU0,Q9BQE5,Q8WTV0,Q14739,Q13510,Q8NBX0,Q15800,P07602,Q86YN1,Q9HB40,Q14914,Q8N2A8,Q16850,O15118,Q8NHP8,P04062,Q9NUQ2,O95470,Q9NPH0,Q96G23,Q53GQ0,P23786,Q9NP80,P51648,P09455,Q9BV10,Q96N66,Q10713,Q99805,O15254,O14773,O43292,P38435,A1L0T0,Q9H2C2,P35790,Q16134,P49356,Q86SQ9,P48449,Q8NF37,O95674,P31751,Q8NCG7,P06865,P06280,Q8WUK0,P04066,Q2T9J0,Q9NZ01,Q9BVG9,P09960,Q8IXJ6,Q15067,P16435,P21964,Q9H7Z7,Q9NZJ7,Q8N4Q0,Q8NBN7,P54646,Q86UY6,Q9H490,Q9UG56,Q9P035,Q9H3P7,P35610,P30536,Q6NUM9,Q6P1A2,Q9BT22,P05023,O15269,P49748,O14735,Q9C0D9,Q9Y2B2,Q14534,O75845,P53985,Q9UBM7 89 +Cellular response to acidic ph 0.8234928527035442 0.7671723017682678 0.4429790787829966 1.0 0.990253692950864 2 Q15907 1 +Cellular response to ph 0.8234928527035442 0.7671723017682678 0.4429790787829966 1.0 0.990253692950864 2 Q15907 1 +Response to acidic ph 0.8234928527035442 0.7671723017682678 0.4429790787829966 1.0 0.990253692950864 2 Q15907 1 +Positive regulation of mitochondrial membrane potential 0.5795789183582559 0.7644877583992055 0.4445766290164359 1.0 0.990253692950864 4 P31751,Q9UJZ1 2 +Anterior posterior pattern specification 0.4074648864743591 0.7632022524161363 0.4453427857053194 1.0 0.990253692950864 17 Q9Y2W6,Q15363,Q8N2A8 3 +Maintenance of protein location 0.3918718872265367 0.7589383663235227 0.4478894268518709 1.0 0.990253692950864 28 P52789,O43292,Q9UH99,O43731,Q9H4A6,P24390 6 +Positive regulation of epithelial cell apoptotic process 0.6886924944743062 0.7548578838057375 0.4503342583674485 1.0 0.990253692950864 3 Q53EL6 1 +Dna modification 0.3904807519577178 0.7532972138546346 0.451271332684243 1.0 0.990253692950864 27 O75844,Q9Y2W6,Q8N2A8 3 +Neuron cellular homeostasis 0.6871993674431724 0.749637846332989 0.4534728504241307 1.0 0.990253692950864 3 P51790 1 +Establishment of protein localization to organelle 0.3714182156079167 0.7472038707907419 0.4549405079267785 1.0 0.990253692950864 190 P56589,Q99797,Q7Z434,P50542,P49458,P13473,P30536,Q9UGP8,Q9UHB9,Q15629,P62072,O60830,Q9Y5J6,O14964,Q7Z4Q2,Q8N8Q8,Q9NS69,Q9Y371,P11279,Q9Y584,Q9H1Z9,O96008,O95831,Q9UHD1,Q8N4H5,Q10713,O00165,P51572,O14737,P61009,Q8NFH5,Q99595,P55786,Q9Y5J9,Q15070,Q9H300,Q8N1F7,Q53FT3,Q9Y5Y5,Q15005,O14925,Q14108,P52789,Q99442,Q9BW27,Q99816,P46379,P61026,Q99523,Q9Y512,O75381,Q9Y5M8 52 +Regulation of leukocyte mediated cytotoxicity 0.4947294627713817 0.7469064646023966 0.4551200234664021 1.0 0.990253692950864 7 P46108,Q9NUQ9,P11279,P04439 4 +Positive regulation of b cell proliferation 0.6860428971091029 0.7456005792443424 0.4559087329000904 1.0 0.990253692950864 3 P14174,P00813 2 +Positive regulation of anion transmembrane transport 0.5740853413082382 0.7426462907783611 0.4576958548448904 1.0 0.990253692950864 4 P08183 1 +Primary alcohol metabolic process 0.4036719876923679 0.7370755306725085 0.4610764186011362 1.0 0.990253692950864 17 Q8NBN7,P30837,P51648 3 +Positive regulation of anion transport 0.4924438208014455 0.7357543884507497 0.4618801837142747 1.0 0.990253692950864 7 P14174,Q15041,P55011,P08183 4 +Regulation of membrane permeability 0.3808102715013467 0.7337540225815316 0.4630986669036374 1.0 0.990253692950864 20 P45880,P52789 2 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.4777556843572127 0.7329207352514716 0.4636067755497748 1.0 0.990253692950864 8 P07602,Q9NZJ7 2 +Bone morphogenesis 0.4918293418008056 0.732759545837177 0.4637050988932591 1.0 0.990253692950864 7 O75844,P16435 2 +Positive regulation of ire1 mediated unfolded protein response 0.6823127137084212 0.7326136502230316 0.4637941032406711 1.0 0.990253692950864 3 P18031,P57088 2 +Positive regulation of endoplasmic reticulum unfolded protein response 0.6823127137084212 0.7326136502230316 0.4637941032406711 1.0 0.990253692950864 3 P18031,P57088 2 +Neurotrophin trk receptor signaling pathway 0.5253089996195077 0.7308634162590442 0.4648625836066022 1.0 0.990253692950864 5 Q99523,Q96B36 2 +Regulation of mast cell activation 0.5709554829497816 0.7302560565538294 0.4652336834279247 1.0 0.990253692950864 4 P09601 1 +Regulation of mast cell activation involved in immune response 0.5709554829497816 0.7302560565538294 0.4652336834279247 1.0 0.990253692950864 4 P09601 1 +Xenobiotic metabolic process 0.4373028969233733 0.7296872141494603 0.4655813982868968 1.0 0.990253692950864 11 O43169,P78417 2 +Positive regulation of cell killing 0.5042746822514279 0.7283913576936876 0.4663740521101902 1.0 0.990253692950864 6 Q9NUQ9,P11279 2 +Positive regulation of glycoprotein metabolic process 0.4764836079354982 0.726401279502427 0.4675928070512807 1.0 0.990253692950864 8 P35610,Q9UHD1,Q08379,Q92542 4 +Positive regulation of autophagy of mitochondrion 0.4902072958659413 0.724860978398072 0.4685373220165891 1.0 0.990253692950864 7 P21796,P27544,P12235 3 +Porphyrin containing compound metabolic process 0.401515005150994 0.7222443157446876 0.4701442817095373 1.0 0.990253692950864 17 O75027,Q7KZN9,P30519,O00264 4 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.4258627837262539 0.7213504339634964 0.4706939343065492 1.0 0.990253692950864 13 P07602,Q9Y4G8,Q9NZJ7 3 +Sensory perception of mechanical stimulus 0.4202189748719887 0.7208661715593364 0.4709918578737391 1.0 0.990253692950864 14 Q9Y5J9,P62072,O76024,Q14108 4 +Response to thyroglobulin triiodothyronine 0.8095090118085791 0.7200374876053127 0.4715019146569033 1.0 0.990253692950864 2 P11166 1 +Antigen processing and presentation of exogenous antigen 0.4885163519704677 0.7166379061435666 0.4735975488299662 1.0 0.990253692950864 7 Q9UIQ6 1 +Camp mediated signaling 0.6770993592855966 0.7145559881625627 0.4748834485427498 1.0 0.990253692950864 3 Q9Y4G8 1 +Regulation of mammary gland epithelial cell proliferation 0.6770282872240959 0.7143105843053391 0.4750351487778537 1.0 0.990253692950864 3 Q07812,Q9NQC3 2 +Prostate gland development 0.5011999544571474 0.7141640836205684 0.4751257231463826 1.0 0.990253692950864 6 P07602 1 +Xenobiotic transport 0.676815550252623 0.7135761534049998 0.4754893076081907 1.0 0.990253692950864 3 P08183 1 +Localization within membrane 0.3695064509087777 0.7123595910818351 0.4762421315685294 1.0 0.9906483421852345 191 P56589,Q4J6C6,Q9H8Y8,P98194,O15118,Q9BRK0,Q9NPA0,Q15363,Q9Y4G8,Q96A33,Q92544,P31751,P43307,Q9BXS4,Q9UHB9,Q15629,P62072,Q9Y5J6,Q15907,O14964,P27105,Q96L92,Q8N4V1,O43752,Q8N8Q8,O43805,O00560,Q9NS69,Q9Y371,Q9BTX1,Q9Y584,Q13641,Q9H4A6,Q9UHD1,P35613,P07602,P57105,Q99805,Q9HD45,Q9Y5J9,Q9HD20,Q15070,Q9Y5Y5,O60725,Q9NZJ7,Q99442,Q8N2H4,P46379,Q9Y512,Q15041,Q5BJH7,O75915,O00264 53 +Positive regulation of glucose metabolic process 0.6757887683401581 0.7100340655178572 0.4776830117071027 1.0 0.9915265808253904 3 P31751 1 +Positive regulation of cellular carbohydrate metabolic process 0.6757887683401581 0.7100340655178572 0.4776830117071027 1.0 0.9915265808253904 3 P31751 1 +Pattern recognition receptor signaling pathway 0.3864194271297732 0.7069376692295557 0.4796052134764585 1.0 0.9915265808253904 30 O43657,Q86UT6,Q9NPR9,Q9NUD5,Q9NQC3 5 +Regulation of cysteine type endopeptidase activity 0.3857585865664634 0.7061637811752726 0.4800862912275083 1.0 0.9915265808253904 43 Q9NR28,Q96K76,O75915,Q9NZJ7,P51572,O14737,Q96A26,P51812,P23396,Q12797,O95831,Q15418,Q15041,P16435,Q15392,Q9BXK5,O75340 17 +Mitotic nuclear membrane organization 0.4863013008578293 0.7058836665215261 0.4802604857976049 1.0 0.9915265808253904 7 Q8IXJ6,Q9H6H4,Q86XL3 3 +Regulation of t cell mediated cytotoxicity 0.6734062713739946 0.7018323779053749 0.4827837042540701 1.0 0.9920295131786592 3 Q9NUQ9 1 +Positive regulation of t cell mediated cytotoxicity 0.6734062713739946 0.7018323779053749 0.4827837042540701 1.0 0.9920295131786592 3 Q9NUQ9 1 +Histone h3 acetylation 0.4464623852963615 0.70180231081779 0.4828024574838538 1.0 0.9920295131786592 10 Q9NRF9,Q03164,Q969T9,Q9Y6J9,Q9NWS0 5 +Regulation of mitochondrial gene expression 0.4276288675250059 0.7005754180282743 0.4835680237433224 1.0 0.9920858137434316 12 Q9Y2R0 1 +Bone development 0.3828207596555805 0.6997682127447108 0.4840720691529838 1.0 0.9920858137434316 26 O75844,Q7RTS9,Q15125,P16435 4 +Carbohydrate derivative biosynthetic process 0.3576688432161675 0.6984149735755731 0.4849177148403172 1.0 0.9925297639950332 173 Q9Y287,Q86SQ9,O15118,Q8TB61,O60502,P35610,Q10472,Q9BXS4,P00846,Q9NQX7,P06865,P50897,Q8N4A0,Q9BT22,P00813,Q53GQ0,Q8NCH0,Q7LGA3,Q9UKU0,Q13126,P31350,O75964,Q9NZ01,Q9NRB3,Q9BV10,Q9UMR5,Q9H4A6,Q8NBX0,Q9Y2B2,Q9HC07,Q99805,P24539,Q8NBI6,Q86YN1,P49915,P16260,O43292,Q9UJZ1,P56385,Q96JB2,O43505,Q7LG56,Q9H490 43 +Locomotory behavior 0.3857254496086691 0.6977285468000859 0.4853469719669205 1.0 0.9930921969367702 31 O15118,O75844,P51790,P10253,O43815,P54802,Q6Y7W6,P50897 8 +Positive regulation of peptidyl lysine acetylation 0.4840196909372861 0.694827910207485 0.4871631548989295 1.0 0.994439874897118 7 P54646,Q9NWS0 2 +Negative regulation of cysteine type endopeptidase activity 0.3905301811258694 0.694428383242563 0.4874135990065622 1.0 0.994439874897118 18 P51812,Q15392,Q15041,P16435,Q15418 5 +Negative regulation of cell aging 0.5613758773576984 0.692593146132614 0.4885649127460718 1.0 0.994439874897118 4 P14174,Q9NX47 2 +Positive regulation of pathway restricted smad protein phosphorylation 0.561129013056577 0.6916280356502813 0.489170950737587 1.0 0.994439874897118 4 Q93062,O00560 2 +Positive regulation of glycolytic process 0.8004972032318193 0.6901269524134458 0.4901143551299756 1.0 0.994439874897118 2 P54646 1 +Microglia differentiation 0.8004972032317994 0.6901269524133802 0.4901143551300169 1.0 0.994439874897118 2 P04062 1 +Glial cell development 0.3894655782013524 0.6869283389537817 0.4921278877176498 1.0 0.994439874897118 18 P05067,Q8IXJ6,O43175,P31751,P08670 5 +Platelet derived growth factor receptor signaling pathway 0.468665928072399 0.6864772429888019 0.492412209996891 1.0 0.994439874897118 8 O95470 1 +Collagen biosynthetic process 0.5597158428804048 0.6861087869962452 0.4926445102837089 1.0 0.994439874897118 4 Q92791 1 +Negative regulation of sister chromatid cohesion 0.6686353745725663 0.6854827949904261 0.4930393138363078 1.0 0.994439874897118 3 Q7Z5K2,Q14674 2 +Regulation of translation at synapse modulating synaptic transmission 0.559390547263675 0.6848396571415503 0.4934451074828168 1.0 0.994439874897118 4 Q7L576,P38919,P35268 3 +Purinergic nucleotide receptor signaling pathway 0.7986326911124951 0.6839870301322353 0.4939833557954751 1.0 0.994439874897118 2 P00813 1 +Negative regulation of cell volume 0.7986326911124949 0.6839870301322336 0.4939833557954762 1.0 0.994439874897118 2 P51790 1 +Endothelial cell apoptotic process 0.798632691112495 0.6839870301322336 0.4939833557954762 1.0 0.994439874897118 2 Q53EL6 1 +Positive regulation of endothelial cell apoptotic process 0.798632691112495 0.6839870301322336 0.4939833557954762 1.0 0.994439874897118 2 Q53EL6 1 +Pathway restricted smad protein phosphorylation 0.5142907383607718 0.6831528430119157 0.4945102672123023 1.0 0.994439874897118 5 Q93062,O00560 2 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.7983219390925823 0.6829653703073858 0.4946287250425025 1.0 0.994439874897118 2 Q15363 1 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.7983219390925823 0.6829653703073858 0.4946287250425025 1.0 0.994439874897118 2 Q15363 1 +Positive regulation of fatty acid metabolic process 0.5131863587978218 0.6784011116565121 0.4975174044538599 1.0 0.994439874897118 5 P50416,P31751,P33897 3 +Negative regulation of ion transmembrane transport 0.4015285185820426 0.6778024690216926 0.4978969453815469 1.0 0.994439874897118 16 P21796,P78417 2 +Glycine metabolic process 0.4666824390778139 0.6763895990887617 0.4987933190895077 1.0 0.994439874897118 8 O43175 1 +Golgi organization 0.3584671496988819 0.6745322376731797 0.4999729973372142 1.0 0.994439874897118 61 Q53FT3,Q9Y3B3,O43752,Q96JB2,Q8NHH9,Q15363,O15260,Q7Z3D4,Q9P2W9,Q9H4A6,Q8TBA6 11 +Cell cycle dna replication 0.387542394835917 0.6733957664118688 0.5006955412780627 1.0 0.994439874897118 18 O75844,P25205,P49736,O75419 4 +Positive regulation of proteolysis 0.2961070048621562 0.6706282871069401 0.5024573576351816 1.0 0.994439874897118 88 Q9NR28,P05067,Q4ZIN3,P04062,Q9P0J0,Q9UHD9,Q6P1A2,P48729,O75340,O43847,P23396,P40763,Q9UL46,Q12797,O95831,Q8IXJ6,P51572,P45974,O14737,Q96JB5,Q92542,P61289,O43765,Q9NZJ7,Q96A26,P46379,Q96HY6,Q9BW61,P54725,O75915,Q9BXK5 31 +Quinone metabolic process 0.4226512068222853 0.6705562613320835 0.5025032539894951 1.0 0.994439874897118 12 Q8NI60,Q8N0U8,O75208 3 +Cellular response to camp 0.510899622369061 0.6685809487608607 0.5037628287205718 1.0 0.994439874897118 5 Q9Y4G8 1 +Regulation of establishment of planar polarity 0.4784295696824767 0.6678389494975281 0.5042364010315921 1.0 0.994439874897118 7 Q9ULK5 1 +Negative regulation of organ growth 0.554182053246346 0.6645889204497377 0.5063134577099482 1.0 0.9951757797877704 4 O94826 1 +Negative regulation of leukocyte mediated immunity 0.5541120685307498 0.6643177349891894 0.5064869724367291 1.0 0.9951757797877704 4 P09601,P04439 2 +Cellular transition metal ion homeostasis 0.3709608904731132 0.6600311245960986 0.5092338560352343 1.0 0.9978251936758674 20 P09601,P05067,Q15904,Q8N511,O75027,O60826,Q9Y487 7 +Respiratory chain complex iii assembly 0.507610354400607 0.6545013641782811 0.5127888485445733 1.0 1.0 5 Q9BSK2 1 +Deoxyribose phosphate metabolic process 0.3980045066536538 0.6543877232985194 0.5128620417881062 1.0 1.0 16 Q9H773,P16260,P00813,Q7LG56 4 +Membrane protein ectodomain proteolysis 0.4501547094839135 0.6520785480166134 0.5143505020363328 1.0 1.0 9 Q9NZ08,O43847,P38159,Q92542 4 +Leukocyte mediated cytotoxicity 0.41444261982307 0.6508445110670862 0.5151468639082526 1.0 1.0 13 P68371,P46108,P07437,P11279,P51809,Q9NUQ9,P04439 7 +Chemical homeostasis 0.3596439404562996 0.6492540223221056 0.5161741987512287 1.0 1.0 182 P55061,P05067,P98194,O15118,Q96AQ8,Q8NF37,Q9P035,P04062,P30519,Q96A33,Q92544,O15260,P35610,Q8IYU8,P30536,P62942,Q15907,P50897,Q9H4I9,P62995,Q8N5M9,Q8N511,Q9Y6C9,P05023,Q16739,Q9BWH2,Q9NP80,Q93050,Q9NQC3,P09455,Q16891,Q8WTV0,Q9Y6B6,Q9Y6M7,Q9UHD1,Q8NE01,O76024,P20020,Q9Y487,P09601,Q9NVV0,Q15904,Q9HC07,P42785,P51572,Q9Y639,Q15067,O15254,O75503,O75027,Q9Y696,O75787,P16615,Q9NWS0,Q96CP7,Q9HD20,Q9Y6N1,P53985,Q9UJZ1,P0CG08,O95202,P52789,Q5BJF2,P33897,P78417,P54646,P51790 67 +Positive regulation of smooth muscle cell apoptotic process 0.549785291549689 0.6476007174227125 0.5172432331482257 1.0 1.0 4 P98175 1 +Bile acid metabolic process 0.4231574587364329 0.6462751973175912 0.5181011476429387 1.0 1.0 11 O14975,Q9H2C2,O15118 3 +Positive regulation of antigen receptor mediated signaling pathway 0.7865133623368556 0.644506019484313 0.5192473555140571 1.0 1.0 2 P00813 1 +Positive regulation of t cell receptor signaling pathway 0.7865133623368556 0.644506019484313 0.5192473555140571 1.0 1.0 2 P00813 1 +Regulation of dna directed dna polymerase activity 0.4484328325631174 0.6429543338483316 0.520253731922883 1.0 1.0 9 Q14691,Q9Y248 2 +Purine nucleobase metabolic process 0.4174603633531971 0.6393853575276441 0.5225722721126058 1.0 1.0 12 P16260,P49915 2 +Purine deoxyribonucleoside monophosphate metabolic process 0.5475888920383243 0.6391524060566434 0.5227237904182993 1.0 1.0 4 P16260 1 +Neurotransmitter catabolic process 0.7846488502175182 0.6385004759265598 0.5231479443431897 1.0 1.0 2 P21964 1 +Gamma aminobutyric acid metabolic process 0.7846488502175017 0.6385004759265066 0.5231479443432243 1.0 1.0 2 O43175 1 +Regulation of amino acid transport 0.5034171845424802 0.6366345890452793 0.5243628894080237 1.0 1.0 5 Q15041,P55011,O75915 3 +Vesicle cargo loading 0.4169140354707633 0.6361133360859301 0.5247025538452799 1.0 1.0 12 Q9NR31,Q96PC5,Q15363,P49755 4 +Entry into host 0.377407457969361 0.6356379179134609 0.5250124491504176 1.0 1.0 30 Q9BTY2,Q14108,O15118,P11279,Q8WTV0,P19474 6 +Mating 0.5463007233086777 0.6342097080893762 0.5259439727643964 1.0 1.0 4 P00813 1 +Attachment of gpi anchor to protein 0.5025688955001625 0.6330316751141973 0.5267129584681729 1.0 1.0 5 O43292,Q9H490 2 +Regulation of neuron projection regeneration 0.5458332363831461 0.6324182180050645 0.5271136326403858 1.0 1.0 4 Q96G23 1 +Positive regulation of release of cytochrome c from mitochondria 0.4710043803327233 0.6322264679097116 0.527238904444713 1.0 1.0 7 Q96A26 1 +Response to muscle activity 0.501950186746001 0.6304063693796159 0.5284287446194396 1.0 1.0 5 Q9UDX5,P54646 2 +Chromosome organization involved in meiotic cell cycle 0.3942262375266194 0.6293666348995426 0.5291090561111371 1.0 1.0 16 Q92791,Q9BTX1,P46379 3 +Positive regulation of establishment of protein localization to mitochondrion 0.4197699550693217 0.6264491979090239 0.5310203486682663 1.0 1.0 11 Q9H270,O14737,Q9Y371,P55786,O43464 5 +Protein processing 0.3745779763097992 0.6253375128409743 0.5317495643823973 1.0 1.0 46 Q9UJZ1,Q15005,Q99797,P42892,Q10713,O75844,P61009,Q2T9J0,O75503,P67812,Q9BXS4,Q12797,Q6P1A2,Q15392,Q9UG56 15 +Sodium ion export across plasma membrane 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 1.0 3 P05026,P05023 2 +Tubulin deacetylation 0.5433579528813326 0.622952825830892 0.5333155224016319 1.0 1.0 4 Q8IXJ6,P54646 2 +Golgi to plasma membrane protein transport 0.3802939827726435 0.6225987548833355 0.5335482296250316 1.0 1.0 18 Q9H4A6,Q4J6C6,Q8N2H4,P98194 4 +Positive regulation of nuclease activity 0.6495772141969142 0.6212374033171316 0.5344434329179122 1.0 1.0 3 P23396 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3775178369889577 0.6209278319910556 0.5346471078712955 1.0 1.0 37 O43657,O60858,Q9Y3E0,Q8TB61,Q5T9L3,Q86UE4,P62942,Q8TCD1 8 +Calcium ion transmembrane transport 0.3762737408744926 0.6194779129296004 0.5356015679386714 1.0 1.0 42 Q9H4I9,Q9NVV0,P98194,Q9HC07,Q96AQ8,Q4KMQ2,Q8IYU8,P16615,P78417,P62942,P21796,Q9UJZ1,P20020 13 +Cytoplasmic pattern recognition receptor signaling pathway 0.3985338959985043 0.6188958133396578 0.53598499676075 1.0 1.0 15 O43657,Q86UT6 2 +Postsynaptic actin cytoskeleton organization 0.5422571555902906 0.6187545562579194 0.5360780635916722 1.0 1.0 4 Q9Y6W5 1 +Purine containing compound biosynthetic process 0.2995222829075314 0.6151217544406403 0.538474316344165 1.0 1.0 80 P00813,Q53GQ0,P16260,P24539,Q8TB61,Q9UKU0,Q13126,P35610,O75964,P49915,Q9NZ01,Q9UMR5,P00846,Q9UJZ1,P50897 15 +Neural retina development 0.4672470144830047 0.6143180102589778 0.5390052034544297 1.0 1.0 7 Q8NBN7,P54802,Q15555 3 +Mammary gland development 0.3720233805965816 0.6134686492887 0.5395665061843604 1.0 1.0 19 P52789,P31751,Q13505 3 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4978820079774815 0.6131984371553713 0.5397451380295974 1.0 1.0 5 Q96K76,P14174 2 +Retrograde transport vesicle recycling within golgi 0.4975751011181194 0.6119041519832509 0.5406011744227448 1.0 1.0 5 Q8TBA6 1 +Phosphatidylglycerol acyl chain remodeling 0.7762585456805272 0.6117134733216674 0.5407273460682627 1.0 1.0 2 Q8NF37 1 +Phosphatidylinositol acyl chain remodeling 0.7762585456805243 0.6117134733216584 0.5407273460682687 1.0 1.0 2 Q96N66 1 +Positive regulation of phospholipid metabolic process 0.540371124315207 0.6115777728587336 0.5408171477265005 1.0 1.0 4 Q9UJZ1 1 +Regulation of dna templated transcription in response to stress 0.4170230825348765 0.6104219732855386 0.5415823160532871 1.0 1.0 11 P09601,Q8IXJ6,Q15418,P51812 4 +Fatty acid beta oxidation using acyl coa oxidase 0.4972178815962969 0.6103983906859628 0.5415979339500672 1.0 1.0 5 Q15067,O15254 2 +Maintenance of location in cell 0.3747286507234759 0.6100889260378581 0.541802901945388 1.0 1.0 43 P52789,P10253,O43292,Q9UH99,O43731,P78417,Q9H4A6,P62942,P24390 9 +Leucine transport 0.775637041640774 0.609745126548968 0.5420306563466857 1.0 1.0 2 Q9H2J7 1 +Deoxyribonucleoside monophosphate catabolic process 0.5393769260643775 0.6078029927549201 0.5433181441534805 1.0 1.0 4 P16260 1 +Negative regulation of nervous system development 0.401366614772905 0.6020223508491407 0.5471592596839425 1.0 1.0 14 Q8IXJ6,Q9Y4G8,Q9NQC3,P30536,Q96G23 5 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 1.0 2 P10321 1 +Negative regulation of cardiac muscle tissue growth 0.6424292385632493 0.5976212659375527 0.5500926712746059 1.0 1.0 3 O94826 1 +Regulation of cell growth involved in cardiac muscle cell development 0.6424292385632493 0.5976212659375527 0.5500926712746059 1.0 1.0 3 O94826 1 +Negative regulation of cell growth involved in cardiac muscle cell development 0.6424292385632493 0.5976212659375527 0.5500926712746059 1.0 1.0 3 O94826 1 +Negative regulation of map kinase activity 0.4632148535907668 0.5951908996207099 0.5517158726788876 1.0 1.0 7 Q96JB5,P04062,Q53EL6 3 +Heart morphogenesis 0.3708966142789401 0.5950722808406478 0.5517951563872208 1.0 1.0 28 O96028,Q9ULK5,O75844,Q15363,Q9NQC3,P62942 6 +Maternal placenta development 0.5359428612236865 0.594809950002557 0.5519705157952612 1.0 1.0 4 Q15363 1 +Deoxyribose phosphate catabolic process 0.4389356040991412 0.5929265152756446 0.5532303320807292 1.0 1.0 9 Q9H773,P16260 2 +Water soluble vitamin metabolic process 0.3619068527200405 0.5928309215591093 0.553294311608334 1.0 1.0 20 P00374,Q96EY8,Q9H2D1,P11166,P78417,Q9H3L0 6 +Response to axon injury 0.375243370234376 0.5874251858481072 0.5569181828292633 1.0 1.0 18 P30536,Q99757,P07196,Q96G23,P00374 5 +Regulation of lipid transport 0.3816247989766215 0.5866953086631486 0.5574083590918866 1.0 1.0 17 O15260,P30536,Q9H2C2,P31751 4 +Nucleoside catabolic process 0.4726665245737446 0.5842870391662466 0.5590272106282657 1.0 1.0 6 P16260,Q13126 2 +Regulation of cell killing 0.4481936995582395 0.5833327359227275 0.5596693292888677 1.0 1.0 8 P46108,Q9NUQ9,P11279,P04439 4 +Intracellular sterol transport 0.4471799990730499 0.5782882063042384 0.563069555477063 1.0 1.0 8 O15118 1 +Aspartate transmembrane transport 0.6363071184333207 0.5776213996315719 0.5635197559215155 1.0 1.0 3 Q9H936,Q9UJS0 2 +Histone h4 deacetylation 0.5311648812618592 0.5768530796120201 0.5640387090428121 1.0 1.0 4 Q8IXJ6 1 +Membrane biogenesis 0.3690418022543987 0.5750593446120347 0.5652511623296199 1.0 1.0 29 Q9Y5Y5,Q86XL3,O75192,Q96CP7,Q9NZZ3 5 +Dendrite extension 0.6353376965302757 0.5744744015413146 0.5656468181473193 1.0 1.0 3 O60271 1 +Neurofilament cytoskeleton organization 0.7641392169049074 0.5737440635930777 0.5661410057940797 1.0 1.0 2 P07196 1 +Cellular response to topologically incorrect protein 0.3713495766057731 0.5707617078848541 0.5681611829526794 1.0 1.0 39 Q9Y4P3,Q9BUN8,Q15363,P46379,Q7Z2K6,Q13438,P57088,Q96HY6,Q9Y679,O76024,P48723 11 +Negative regulation of ion transport 0.3653468220467192 0.5656898329606747 0.571604647895553 1.0 1.0 19 P21796,P78417 2 +Protein n linked glycosylation 0.3626323483029076 0.560602417212783 0.575068603318202 1.0 1.0 24 Q86SQ9,Q9HC07,Q86YN1,Q9BV10,Q9BT22 5 +Protein maturation 0.3289635087788609 0.5564305683633143 0.5779165467153606 1.0 1.0 69 Q15005,Q99797,P42892,Q10713,O75844,Q86UY6,Q2T9J0,Q9BU89,O75503,P67812,Q9BXS4,Q9BU23,P62942,O76024,Q15392,Q9UG56 16 +Regulation of translation in response to stress 0.4074841054628754 0.5551490060867537 0.5787927451575894 1.0 1.0 11 Q15418,Q15363,Q9BWF3,P51812 4 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.5250082211672107 0.5539325043500724 0.5796250389296216 1.0 1.0 4 Q8IXJ6 1 +Intraciliary transport involved in cilium assembly 0.7573026724673757 0.5527253339719244 0.580451503069455 1.0 1.0 2 Q15154 1 +Cellular response to lipoprotein particle stimulus 0.6285159745203504 0.5524889332389854 0.5806134145403055 1.0 1.0 3 O15118 1 +Metal ion export 0.4418431884412458 0.5518433007394695 0.5810557176345319 1.0 1.0 8 Q4KMQ2,P05023,P20020 3 +Organ growth 0.3573702738946969 0.5491086768318788 0.5829308709766703 1.0 1.0 21 O75844,P07602,P16435,P10644 4 +Membrane protein intracellular domain proteolysis 0.7554381603480468 0.5470452377878283 0.584347653365789 1.0 1.0 2 Q92542 1 +Cyclic nucleotide mediated signaling 0.5231318371886611 0.5469977476156686 0.5843802795505104 1.0 1.0 4 Q9Y4G8 1 +Cellular response to sterol depletion 0.4639870271182391 0.5457204527879929 0.5852581106197805 1.0 1.0 6 Q15363 1 +3 utr mediated mrna stabilization 0.4404957568157678 0.5451977724732612 0.5856175033842344 1.0 1.0 8 P98175 1 +Nucleobase containing small molecule catabolic process 0.4524278882980971 0.5445307150822911 0.5860763179801047 1.0 1.0 7 P16260,Q13126 2 +Cellular response to fatty acid 0.4812802959928005 0.5440407930790884 0.5864134017081164 1.0 1.0 5 P50416,Q96GM5,P13010 3 +Terpenoid biosynthetic process 0.4635755494406393 0.5439049594194569 0.586506876000243 1.0 1.0 6 P09455 1 +Activated t cell proliferation 0.480712406285943 0.5417080839993905 0.58801961986789 1.0 1.0 5 P23396,P10644 2 +Response to glycoside 0.7532628962088191 0.5404474134010746 0.5888885173227634 1.0 1.0 2 P05023 1 +Cdp choline pathway 0.753262896208802 0.5404474134010234 0.5888885173227987 1.0 1.0 2 P35790 1 +Regulation of lipid catabolic process 0.4171616488825282 0.5395980677485808 0.5894742494582061 1.0 1.0 10 Q8NCG7,P31751,Q8WTV0 3 +Interleukin 6 mediated signaling pathway 0.5210387042640634 0.5392908556702039 0.5896861775015922 1.0 1.0 4 P40763,Q13546 2 +Alcohol catabolic process 0.4043268285389476 0.5370003260662269 0.5912673888231392 1.0 1.0 11 P30837,Q10713,Q8WTV0 3 +Ubiquitin dependent endocytosis 0.7520198881292772 0.536691377333405 0.5914808131353397 1.0 1.0 2 Q99816 1 +Purine nucleoside biosynthetic process 0.4616189401727076 0.535288858839428 0.5924501291752988 1.0 1.0 6 Q13126 1 +Regulation of fat cell differentiation 0.3953202070536862 0.5345400639586019 0.5929679384499513 1.0 1.0 13 Q86X55,Q8IXJ6,Q99523,Q8N4Q0 4 +Regulation of histone h3 k14 acetylation 0.7501553760099192 0.5310768216859998 0.5953655453008175 1.0 1.0 2 Q03164 1 +Histone h3 k14 acetylation 0.7501553760099192 0.5310768216859998 0.5953655453008175 1.0 1.0 2 Q03164 1 +Regulation of epithelial cell apoptotic process 0.4269036046282112 0.5303810692212438 0.5958477486778384 1.0 1.0 9 P09601,O76024,Q53EL6 3 +Neuromuscular process controlling balance 0.3989867250444585 0.5298410260206572 0.5962221577272162 1.0 1.0 12 P10253,P17900,O14773,P07196,Q6Y7W6 5 +Retina development in camera type eye 0.372873197924684 0.5279771263552856 0.5975152119374969 1.0 1.0 17 Q8NF37,Q8NBN7,P54802,Q9Y696,Q15555 5 +Ubiquitin dependent erad pathway 0.3656198004782772 0.5241161080418527 0.600197785549784 1.0 1.0 36 Q9UBV2,O60858,Q9BUN8,P51572,Q9UBU6,Q96A33,Q92575,P46379,Q13438,Q9UHD9,Q9Y679,P27824,O76024 13 +Peptidyl arginine methylation 0.4761649994902031 0.5231141447316794 0.6008948228195958 1.0 1.0 5 Q6P2P2 1 +Peptidyl arginine n methylation 0.4761649994902031 0.5231141447316794 0.6008948228195958 1.0 1.0 5 Q6P2P2 1 +Regulation of protein folding 0.5164800995024803 0.5226145536915271 0.6012425106089321 1.0 1.0 4 P08621,Q9UL15,O14737 3 +Response to sterol depletion 0.4475498137457627 0.5218889009041475 0.6017476865891207 1.0 1.0 7 Q15363 1 +Leptin mediated signaling pathway 0.7458048477315153 0.5180685308791912 0.6044104555770318 1.0 1.0 2 Q16739 1 +Eating behavior 0.7458048477315151 0.51806853087919 0.6044104555770327 1.0 1.0 2 P50416 1 +Positive regulation of metallopeptidase activity 0.7458048477315126 0.5180685308791827 0.6044104555770378 1.0 1.0 2 Q96HY6 1 +Regulation of smad protein signal transduction 0.5144881291059474 0.5153754413991555 0.6062906903730465 1.0 1.0 4 Q93062 1 +Regulation of necrotic cell death 0.396478513753362 0.5151688091144698 0.6064350628745643 1.0 1.0 12 Q13510,P12235 2 +Negative regulation of calcineurin mediated signaling 0.6164534379699727 0.5143318331873872 0.6070200091396516 1.0 1.0 3 Q9UHD1 1 +Negative regulation of calcium mediated signaling 0.6164534379699727 0.5143318331873872 0.6070200091396516 1.0 1.0 3 Q9UHD1 1 +Neurotransmitter metabolic process 0.5135326484191653 0.5119136653682678 0.6087114337589468 1.0 1.0 4 Q8NCG7,P21964 2 +Negative regulation of protein serine threonine kinase activity 0.3762610103515367 0.5118569126059324 0.6087511555409939 1.0 1.0 16 Q53EL6,P04062,Q96JB5,Q96SZ6,P10644,Q9UHD1,O00410 7 +Heparan sulfate proteoglycan metabolic process 0.4551750591504049 0.5071153561308285 0.6120738809260087 1.0 1.0 6 Q99805 1 +Heparan sulfate proteoglycan biosynthetic process 0.4551750591504049 0.5071153561308285 0.6120738809260087 1.0 1.0 6 Q99805 1 +Central nervous system neuron differentiation 0.3753633703087419 0.5060609614406837 0.6128138548586688 1.0 1.0 16 Q9Y4G8,Q6Y7W6,O14949 3 +Negative regulation of secretion 0.3694266213156427 0.5050519015596137 0.6135223826816327 1.0 1.0 17 Q8N5M9,P00813,P17858,Q16850 4 +Metal ion transport 0.2959806750668176 0.5041462717867277 0.6141585929288365 1.0 1.0 103 P98194,Q96AQ8,P30536,P62942,Q15907,P21796,P27105,Q8N4V1,Q9H4I9,O75844,P05023,Q9Y6M7,O76024,Q9HC07,Q9H2J7,O15173,O75027,P16615,Q9HD20,P78417 20 +Positive regulation of receptor signaling pathway via stat 0.7402113113735013 0.501537933104526 0.6159925882891271 1.0 1.0 2 Q9NX40 1 +Acidic amino acid transport 0.409982294429588 0.5007475568400795 0.6165487981766864 1.0 1.0 10 O60831,P55011,Q15042,Q15041,O75915,Q9UJS0 6 +Negative regulation of cell development 0.3557823746767679 0.4979855998656218 0.6184941919216802 1.0 1.0 19 Q8IXJ6,Q9Y4G8,P30536,Q9NQC3,Q96G23 5 +Regulation of peptidyl lysine acetylation 0.3682279672497643 0.4971080591108857 0.6191128517664537 1.0 1.0 17 O75844,Q03164,P54646 3 +Regulation of lysosomal protein catabolic process 0.6109039433383261 0.4971042335432984 0.6191155493549707 1.0 1.0 3 P04062 1 +Regulation of protein catabolic process in the vacuole 0.6109039433383261 0.4971042335432984 0.6191155493549707 1.0 1.0 3 P04062 1 +Regulation of calcium ion transmembrane transport 0.3487419137655003 0.4964520153744293 0.619575534181126 1.0 1.0 20 P21796,P78417 2 +Positive regulation of long term synaptic potentiation 0.6106510119585831 0.4963241609253011 0.6196657225599178 1.0 1.0 3 Q9Y639 1 +Branched chain amino acid biosynthetic process 0.7380360472342808 0.4951697852672829 0.6204802767811486 1.0 1.0 2 A1L0T0 1 +Cellular response to virus 0.3507384119207075 0.4904872284090384 0.6237891651245013 1.0 1.0 22 O43657,Q86UT6 2 +Protein localization to membrane raft 0.4677945068397918 0.4893050318611428 0.6246257591873792 1.0 1.0 5 P05026,Q9BRK0,O75955 3 +Mitochondrion localization 0.3609611370238206 0.4891995108860678 0.6247004557819864 1.0 1.0 18 Q96H55,Q6PJG6,O75153,Q8IWA4,P07196 5 +Cell adhesion molecule production 0.5065996174183723 0.4870064418558422 0.6262537658526681 1.0 1.0 4 Q9H4A6,O75955 2 +Non motile cilium assembly 0.3910323631048417 0.483506338890545 0.6287362600056134 1.0 1.0 12 Q9ULK5,Q15154 2 +Golgi vesicle transport 0.3166410582349422 0.4814304915128466 0.6302105699837237 1.0 1.0 134 Q4J6C6,P98194,Q15363,O15260,O14653,P24390,O43264,O60499,O75340,O43752,Q5JRA6,Q9Y282,Q12893,P11279,O95249,O43731,Q9Y6B6,Q9H4A6,Q9Y3B3,Q96RQ1,P51572,P49755,Q9P2W9,O00743,Q9HCU5,Q96PC5,Q12907,Q8TBA6,Q9Y5X2,Q96JB2,Q9BVK6,Q9NR31,Q8N2H4,Q8NHH9,O15258,P61026,Q99523,O14828,Q969X5,O95070,Q5BJH7 41 +Lactation 0.406342709112781 0.481221434097227 0.6303591286939012 1.0 1.0 10 Q13505 1 +Folic acid containing compound metabolic process 0.3762662596558081 0.4777599394839941 0.6328210770926672 1.0 1.0 15 Q9H2D1 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4166084249718316 0.4777492547543293 0.6328286828043925 1.0 1.0 9 P61978,Q96K76,P14174,P23396 4 +Macromolecule deacylation 0.3598043781289541 0.4757973536441031 0.6342187553805718 1.0 1.0 37 P23246,Q9H4L7,Q8IXJ6,Q96PK6,O43823,P54646,Q9UMR5,Q9NUJ1,P50897 9 +Response to molecule of bacterial origin 0.3595206043695612 0.4734995721241897 0.635856806176931 1.0 1.0 37 Q53EL6,Q8IXJ6,Q86UE4,P51812,O43823,P30536,Q8WTV0,P08670,Q9NUQ9,Q9NZZ3 10 +Protein peptidyl prolyl isomerization 0.3507508235658268 0.4720948799745052 0.6368590668717278 1.0 1.0 24 Q9NWM8,Q8WUA2,Q02790,Q9Y680,P26885,Q96AY3,P62942,Q5T1M5 8 +Regulation of leukocyte degranulation 0.4363280774102371 0.4705184720670559 0.6379846400051385 1.0 1.0 7 P09601,P11279,P51809 3 +Calcium ion regulated exocytosis 0.4359449511889269 0.4687835374097736 0.6392243683360723 1.0 1.0 7 P16615,Q68EM7,Q9BRK5,P51809 4 +Negative regulation of natural killer cell mediated immunity 0.7287134866376689 0.468273211197721 0.6395892231020031 1.0 1.0 2 P04439 1 +Cellular response to muramyl dipeptide 0.6014343340438129 0.4682134343857754 0.6396319658937997 1.0 1.0 3 Q9NZZ3 1 +Positive regulation of metaphase anaphase transition of cell cycle 0.4142011834319549 0.4655766108572648 0.6415185878847445 1.0 1.0 9 Q9UJX5,Q14674,Q96MF7,Q9UJX2,Q9UJX4,Q15398,P30260,Q9UJX3 8 +Regulation of lipid metabolic process 0.3433914521340702 0.4649184917261847 0.6419898276199345 1.0 1.0 58 Q9H6K4,Q8NF37,P30536,P31751,Q6P1A2,Q8NCG7,Q96G23,O75844,P05023,Q2T9J0,P49748,Q8WTV0,Q13510,Q96N66,P07602,Q9UBM7,P16435,Q9NZJ7,Q9H2C2 19 +Response to mineralocorticoid 0.4346774325012719 0.4630531540924114 0.643326267383429 1.0 1.0 7 P07196,O95831 2 +Negative regulation of production of molecular mediator of immune response 0.5994482612972682 0.4622382022267129 0.6439105104843132 1.0 1.0 3 P09601 1 +Positive regulation of receptor catabolic process 0.7237414543194589 0.4541984224538771 0.6496860183813871 1.0 1.0 2 Q96J02 1 +Regulation of perk mediated unfolded protein response 0.7237414543194547 0.4541984224538654 0.6496860183813955 1.0 1.0 2 P57088 1 +Receptor localization to synapse 0.3894646439675331 0.4527315353061247 0.6507420687709877 1.0 1.0 11 P57105 1 +Positive regulation of protein dephosphorylation 0.3815112299546969 0.4524373310378852 0.6509539586340725 1.0 1.0 13 P04062,Q86XL3 2 +Cerebral cortex cell migration 0.4006447769657945 0.4509025782681894 0.6520597652095359 1.0 1.0 10 Q96N66 1 +Regulation of amino acid transmembrane transport 0.5953354447918394 0.4499603400916954 0.6527390377635633 1.0 1.0 3 Q15041 1 +L glutamate import across plasma membrane 0.5953354447918394 0.4499603400916954 0.6527390377635633 1.0 1.0 3 Q15041 1 +Regulation of l glutamate import across plasma membrane 0.5953354447918394 0.4499603400916954 0.6527390377635633 1.0 1.0 3 Q15041 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.410868597278097 0.448815427569547 0.6535648086698602 1.0 1.0 9 Q10713 1 +Negative regulation of signal transduction by p53 class mediator 0.457494470975609 0.448508242502965 0.6537864388886179 1.0 1.0 5 Q7LG56 1 +Positive regulation of toll like receptor signaling pathway 0.4572230560524309 0.447446037903925 0.6545530415989131 1.0 1.0 5 Q9NQC3 1 +Positive regulation of protein glycosylation 0.720944686140465 0.4463663793142287 0.6553326144776439 1.0 1.0 2 Q9UHD1 1 +Positive regulation of organic acid transport 0.4405053181006785 0.4442521090839433 0.6568603216705831 1.0 1.0 6 Q15042,P14174,Q15041,P55011 4 +Protein maturation by protein folding 0.4563041270264767 0.4438548128713653 0.6571475561931417 1.0 1.0 5 P62942 1 +Mammary gland epithelium development 0.4192443970269039 0.442306288447537 0.6582675810433529 1.0 1.0 8 P31751 1 +Protein targeting to vacuole 0.3650810824611358 0.4402979146190299 0.6597213509145621 1.0 1.0 16 Q99523,O14964,Q14108,P13473 4 +Eosinophil mediated immunity 0.7181479179614729 0.438596646449758 0.6609538274009161 1.0 1.0 2 P51809 1 +Eosinophil activation 0.7181479179614729 0.438596646449758 0.6609538274009161 1.0 1.0 2 P51809 1 +Protein localization to vacuole 0.3419529847410029 0.4368694603757344 0.6622060210985572 1.0 1.0 21 Q14108,Q9Y371,P13473,Q99523,Q9NQC3,O14964 6 +Folic acid containing compound catabolic process 0.5899406032080865 0.434055970283271 0.6642477975333816 1.0 1.0 3 Q9NRN7 1 +Axonal transport of mitochondrion 0.4536475219027912 0.4335173197295566 0.6646389863100122 1.0 1.0 5 P07196,O60313 2 +Myelin assembly 0.437763981953467 0.4327203171992573 0.6652179678091681 1.0 1.0 6 Q9NR77,O15228 2 +Regulation of peptidase activity 0.3075648642697078 0.4312084350237161 0.6663168212473347 1.0 1.0 73 Q9NR28,P05067,Q9P0J0,Q15392,O75340,O43847,Q96K76,P23396,P40763,Q9UL46,Q12797,O95831,P51572,O14737,P49755,P51812,Q9NWS0,Q92542,P16435,P61289,Q9NZJ7,Q96A26,Q96HY6,Q15418,Q15041,O75915,Q9BXK5 27 +Allantoin metabolic process 0.490369013458618 0.4302579524895226 0.6670080099417981 1.0 1.0 4 P16260 1 +Face development 0.4155756131604559 0.424957110363178 0.6708679408731193 1.0 1.0 8 O95470 1 +Cenp a containing chromatin organization 0.7131758856432426 0.4249403177297689 0.6708801826966255 1.0 1.0 2 Q6IPU0 1 +Negative regulation of membrane potential 0.5859061568010568 0.4223151258028318 0.6727950191131553 1.0 1.0 3 O75915 1 +L ascorbic acid metabolic process 0.4872875023044268 0.419749377804804 0.6746685491965219 1.0 1.0 4 P78417 1 +Fatty acid metabolic process 0.2890946674222937 0.41695636780181 0.6767103224751891 1.0 1.0 102 Q9P035,O95470,P31751,Q8NCG7,Q9BWD1,Q53GQ0,P23786,Q8NCC3,Q9UKU0,Q9NP80,Q2T9J0,P51648,Q9NZ01,Q13510,Q15800,Q15067,O15254,P16435,Q9H7Z7,A1L0T0,Q8N4Q0,Q14914,P54646,Q16134 24 +Regulation of animal organ morphogenesis 0.4043889850449679 0.4165458041385497 0.6770106575933381 1.0 1.0 9 Q9ULK5 1 +Response to iron ion 0.4338629525490707 0.4164366678886902 0.6770905014768858 1.0 1.0 6 P09601,P02786,P36551 3 +Urogenital system development 0.3508603052296574 0.4164142952769924 0.6771068696874774 1.0 1.0 46 P07602,Q9NZJ7,O75844,Q9BW27,P35610,P46379,O95470,Q7LG56,Q9ULK5,O76024 10 +Cartilage development 0.3662983697349471 0.4161987847111683 0.6772645489547366 1.0 1.0 15 O75844,Q96HY6,P16435 3 +Negative regulation of transmembrane transport 0.3374381596749826 0.4153705504160787 0.6778706618462018 1.0 1.0 20 P31751,P21796,P78417 3 +Regulation of protein acetylation 0.3367510506568797 0.4105019835971369 0.6814377486949665 1.0 1.0 20 O75844,Q03164,P54646 3 +Plasma membrane organization 0.348997884338581 0.4100705268244587 0.6817542124008356 1.0 1.0 31 Q9H2C2,Q16739,Q9Y371,Q9UQB8,P31751,P33897,P16615,Q96CP7,Q9NZZ3 9 +Fructose 6 phosphate metabolic process 0.4226980179739259 0.4096492933929363 0.6820632315410566 1.0 1.0 7 P52789 1 +Execution phase of apoptosis 0.381631077923328 0.4092134058336983 0.6823830571720633 1.0 1.0 11 O95831 1 +Release of cytochrome c from mitochondria 0.3600755620624887 0.4087491608126876 0.6827237523837388 1.0 1.0 16 Q9H3K2 1 +Ketone biosynthetic process 0.411597776041121 0.4063027181454191 0.6845201884528793 1.0 1.0 8 Q8NI60,O75208 2 +Response to antibiotic 0.4217242452536537 0.4053717084004891 0.6852043037317181 1.0 1.0 7 P07900,P04637,P61160,O60341,P50416,P22681 6 +Purine containing compound salvage 0.4216546181415739 0.4050662350307979 0.6854288249108413 1.0 1.0 7 Q13126 1 +Negative regulation of cellular response to growth factor stimulus 0.3918379022702025 0.4047014176520439 0.6856969999993425 1.0 1.0 10 P18031,O14964,Q05D32,O75340 4 +Establishment of tissue polarity 0.4006032658173887 0.3979002786788886 0.6907036946112699 1.0 1.0 9 Q9ULK5 1 +Protein localization to microtubule end 0.7026103169670559 0.3966053688864076 0.6916584928013907 1.0 1.0 2 Q15555 1 +Maintenance of location 0.3192710013647386 0.3926217510580435 0.6945988720429275 1.0 1.0 67 P52789,P04062,O95674,O43292,P10253,P35610,Q9UH99,O43731,Q9Y679,Q8WTV0,Q9H4A6,P78417,P62942,P24390 14 +Regulation of long term neuronal synaptic plasticity 0.4427034985480936 0.3916648147542942 0.6953058908514906 1.0 1.0 5 Q9Y639 1 +Phosphatidylinositol dephosphorylation 0.4425974214133108 0.3912651773868791 0.6956012357363226 1.0 1.0 5 Q10713 1 +Nuclear envelope organization 0.3476613275364339 0.3904990724849106 0.6961675410277546 1.0 1.0 33 P50402,Q86XL3,O75844,Q8IXJ6,Q9H6H4,Q9ULX6,Q6NUK4,Q9UH99,Q8N1F7,Q9NZZ3 10 +Respiratory gaseous exchange by respiratory system 0.3888875556763698 0.3894194395571942 0.696965894044175 1.0 1.0 10 Q7KZN9 1 +Protein localization to endoplasmic reticulum exit site 0.4782251208234505 0.3893737103455212 0.6969997167078184 1.0 1.0 4 P51572 1 +Amide transport 0.3490575517694804 0.38884942388722 0.6973875373393625 1.0 1.0 42 P07602,Q9NZJ7,Q03518,O00400,Q8N5M9,Q9H2D1,P08183,Q15907,P17858 9 +Nadh regeneration 0.4271032790601188 0.3885897021296114 0.6975796857586594 1.0 1.0 6 P52789 1 +Positive regulation of erk1 and erk2 cascade 0.3568238512077415 0.3884374370207882 0.6976923441763379 1.0 1.0 16 Q9Y4G8,Q13641 2 +Cellular modified amino acid catabolic process 0.3886170290839617 0.3880233923874441 0.6979987225924424 1.0 1.0 10 Q9UHG3 1 +Hematopoietic stem cell homeostasis 0.4417085963368999 0.3879213111709718 0.6980742666560906 1.0 1.0 5 Q56VL3,Q9NX40 2 +Regulation of nervous system process 0.3775397230406827 0.3867695873270148 0.6989267941380859 1.0 1.0 11 Q9UQB8 1 +Purine deoxyribonucleoside metabolic process 0.5726254469749539 0.3846329292121855 0.7005093936170317 1.0 1.0 3 P16260 1 +Deoxyribonucleoside catabolic process 0.5726254469749539 0.3846329292121855 0.7005093936170317 1.0 1.0 3 P16260 1 +Purine deoxyribonucleoside monophosphate catabolic process 0.5726254469749539 0.3846329292121855 0.7005093936170317 1.0 1.0 3 P16260 1 +Receptor signaling pathway via stat 0.3558682660578005 0.3824973695694292 0.7020924796278107 1.0 1.0 16 Q13610,Q56VL3,P40763,Q9NX40,O14964,Q9H490 6 +Collateral sprouting in absence of injury 0.6970167806090788 0.3819936818836383 0.7024660510544629 1.0 1.0 2 P05067 1 +Dna strand elongation involved in dna replication 0.3692953769210029 0.3815533245807717 0.7027927109601526 1.0 1.0 13 Q9NRF9,Q14691,P25205 3 +Inositol lipid mediated signaling 0.3604203993358472 0.380490912144212 0.7035810412602272 1.0 1.0 15 Q10713,O00165 2 +Cellular response to unfolded protein 0.3456149805771362 0.3793182383437503 0.704451557639691 1.0 1.0 32 Q9Y4P3,Q9BUN8,Q15363,Q7Z2K6,Q13438,P57088,Q96HY6,O76024,P48723 9 +Sodium ion transmembrane transport 0.3385121046614571 0.3786147978121386 0.7049739318241703 1.0 1.0 19 Q4KMQ2,Q9H2J7,P05023,Q9Y6M7,Q9UHD1,P27105 6 +Post embryonic development 0.3644743713187121 0.3777471918801171 0.7056184066774778 1.0 1.0 14 Q6Y7W6,Q96A33,O95470,P51649,Q9NX62 5 +Regulation of cellular respiration 0.3443044150026182 0.377694250153151 0.7056577396826693 1.0 1.0 18 Q9NZ45,Q9BSK2,P14406,O14548 4 +Response to salt stress 0.4148770619358798 0.3755841249625364 0.7072260945693616 1.0 1.0 7 Q07812,O95202,P04637,P15121,Q9BPX6,P13010 6 +Thioester biosynthetic process 0.3384858007625131 0.3738188591431534 0.7085390875071198 1.0 1.0 25 Q53GQ0,Q9UKU0,Q9NZ01,Q9UMR5,P50897 5 +Interferon gamma production 0.4144510042236587 0.373747974792987 0.7085918289376032 1.0 1.0 7 Q9NUQ9,Q08722 2 +Regulation of natural killer cell mediated immunity 0.437776926738739 0.3732324055844259 0.7089754797232324 1.0 1.0 5 P46108,P11279,P04439 3 +Regulation of ryanodine sensitive calcium release channel activity 0.4225813005513559 0.370236577213164 0.7112062252289024 1.0 1.0 6 P78417 1 +Response to manganese ion 0.4366527407783886 0.3690636742032857 0.7120802643624313 1.0 1.0 5 P30536,P05067,P02786 3 +Protein geranylgeranylation 0.5669445810715913 0.3689867654027706 0.7121375894955955 1.0 1.0 3 P49354 1 +Lipid oxidation 0.3461272631716712 0.3686236901344945 0.7124082350799079 1.0 1.0 44 Q9BWD1,P23786,O14975,A1L0T0,Q15067,P50542,O15254,P35610,Q2T9J0,P49748,P50416,P31751,O14734,P33897,Q16134,Q709F0,P16435 17 +Negative regulation of phosphatase activity 0.4132012728179164 0.3683741909888086 0.7125942391213382 1.0 1.0 7 P62942 1 +Hydrogen sulfide biosynthetic process 0.6901802361715135 0.3645129464745065 0.7154750079403485 1.0 1.0 2 P25325 1 +Positive regulation of defense response to virus by host 0.4207765528779407 0.3629761647617955 0.7166226895821244 1.0 1.0 6 Q7Z434 1 +Regulation of dendrite morphogenesis 0.3619127296850539 0.3627654455216123 0.7167801064769823 1.0 1.0 14 Q9UQB8 1 +Regulation of protein exit from endoplasmic reticulum 0.4020155710798289 0.362083976108299 0.7172892776046689 1.0 1.0 8 Q9NR31,P51572,Q13438,Q92544 4 +Insulin like growth factor receptor signaling pathway 0.4697347790729773 0.3616691686609571 0.717599269373371 1.0 1.0 4 Q6Y7W6,P11717 2 +Intestinal lipid absorption 0.563420265710063 0.3594281842264356 0.7192747935210013 1.0 1.0 3 Q6P1A2 1 +Fibroblast proliferation 0.3569117411766786 0.3594112656722558 0.7192874482158191 1.0 1.0 15 O75844,Q7Z5K2 2 +Cellular response to calcium ion 0.3926566962557026 0.3593031770156282 0.7193682978956308 1.0 1.0 9 Q9Y696,P54646,Q6NUK1 3 +Positive regulation of smad protein signal transduction 0.5633692575020075 0.3592906860058732 0.7193776412999204 1.0 1.0 3 Q93062 1 +Modified amino acid transport 0.4339735508988891 0.3591859903292678 0.7194559563957372 1.0 1.0 5 Q9H2D1 1 +Negative regulation of mitochondrion organization 0.3469275775518198 0.3589498885252868 0.7196325775094254 1.0 1.0 17 Q9H3K2,Q9H300,Q99536,P30536 4 +Positive regulation of protein monoubiquitination 0.6876942200124339 0.358261483626523 0.720147639256947 1.0 1.0 2 O75340 1 +Regulation of protein monoubiquitination 0.6876942200124339 0.358261483626523 0.720147639256947 1.0 1.0 2 O75340 1 +Regulation of response to osmotic stress 0.4686535946598651 0.358195891123512 0.7201967219337047 1.0 1.0 4 P08183 1 +Vascular transport 0.3687029365550104 0.3570523263453695 0.7210526332421368 1.0 1.0 12 P53985,P08183,P30825 3 +Positive regulation of receptor internalization 0.561081753186206 0.35314950155323 0.7239763637141428 1.0 1.0 3 Q96CW1,Q06787 2 +Fatty acyl coa catabolic process 0.6855189558732122 0.352838149486313 0.7242097816687549 1.0 1.0 2 P33897 1 +Positive regulation of endothelial cell proliferation 0.3995995224231864 0.3511055279018195 0.7255091809657106 1.0 1.0 8 P09601,O75340 2 +Dendrite arborization 0.5603062594163478 0.3510787327069368 0.7255292825449553 1.0 1.0 3 Q13641 1 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.3674874287050627 0.350350533948494 0.726075644830166 1.0 1.0 12 Q92896,Q13526,Q9UNE7,Q05D32,Q8N0X7,P62942 6 +Tetrapyrrole biosynthetic process 0.3635571345476299 0.348932657723532 0.7271398669058611 1.0 1.0 13 O75027,Q7KZN9,O00264 3 +Ribonucleoside triphosphate biosynthetic process 0.3383109680680637 0.3488687921697381 0.7271878151863915 1.0 1.0 28 P00846,P24539,Q9UJZ1,O75964 4 +Regulation of rig i signaling pathway 0.4084445314446051 0.3480892835046533 0.7277731322033898 1.0 1.0 7 Q86UT6 1 +Negative regulation of lipase activity 0.5591171019652182 0.347914439334367 0.7279044409139732 1.0 1.0 3 P16435 1 +Regulation of cell adhesion mediated by integrin 0.4168078469217415 0.3471439613260507 0.728483168262098 1.0 1.0 6 P00813 1 +Protein heterotetramerization 0.4081758357018583 0.3469516018625029 0.7286276789388322 1.0 1.0 7 P31350,Q9NSD9 2 +Establishment or maintenance of transmembrane electrochemical gradient 0.6821006836544514 0.3444047087538908 0.7305419481625661 1.0 1.0 2 P05026 1 +Regionalization 0.32859672307001 0.3424240235104471 0.7320318118891675 1.0 1.0 21 Q9Y2W6,Q15363,Q8N2A8 3 +Positive regulation of viral life cycle 0.3976563484175348 0.342328511154907 0.7321036814994768 1.0 1.0 8 Q99816,P19474,P52292 3 +Negative regulation of ire1 mediated unfolded protein response 0.680857675574872 0.34136517869417 0.7328286857858985 1.0 1.0 2 Q96HY6 1 +Regulation of defense response to virus by host 0.4067849361967043 0.3410766730002066 0.7330458616820126 1.0 1.0 7 P07900,O60828,P42224,Q7Z434,Q08211,O94826 6 +Neuron apoptotic process 0.340273913789123 0.3402877877866312 0.733639812940879 1.0 1.0 49 Q9NR28,P04062,Q96A26,Q01105,P31751,O95831,O76024,Q99720,P50897 9 +Regulation of electron transfer activity 0.4629975124378036 0.340234363386849 0.7336800419121257 1.0 1.0 4 Q99623,Q9NRA0,Q9BSH4 3 +Positive regulation of monocyte chemotaxis 0.5561521375299368 0.3400835944242619 0.7337935760081211 1.0 1.0 3 Q4KMQ2 1 +Deoxyribonucleoside triphosphate catabolic process 0.4150156875203037 0.3400562940173712 0.7338141347546112 1.0 1.0 6 Q9H773 1 +Nucleoside triphosphate catabolic process 0.4150156875203037 0.3400562940173712 0.7338141347546112 1.0 1.0 6 Q9H773 1 +Gliogenesis 0.3367240870715481 0.3392780382557587 0.7344002854675011 1.0 1.0 53 O75306,Q96N66,Q8IXJ6,P04062,P30536,Q9NQC3,P31751,O43175,Q96G23 9 +Polyadenylation dependent snorna 3 end processing 0.4144368388301139 0.3377754222846068 0.7355324326151396 1.0 1.0 6 Q9NQT5,Q01780,Q9NQT4,O95453,Q5RKV6 5 +Selective autophagy 0.3385979926624782 0.3376501054838471 0.735626878651588 1.0 1.0 30 P05141,O94874,O43464,Q86VR2,P27544,O15269,P12235,Q9Y6I9,Q99623,Q96HY6,Q9Y679,A6NDU8,P21796,Q16543,Q6UWE0 15 +Cellular response to growth hormone stimulus 0.5544626319788308 0.3356592756182373 0.7371278191045669 1.0 1.0 3 P40763 1 +Growth hormone receptor signaling pathway via jak stat 0.5544626319788308 0.3356592756182373 0.7371278191045669 1.0 1.0 3 P40763 1 +Response to purine containing compound 0.3571833174823366 0.3353623117210804 0.7373517943357755 1.0 1.0 14 P35613,P05067,Q9Y4G8,Q86X55 4 +Golgi to lysosome transport 0.4263181378742909 0.3314217661481368 0.7403259260346586 1.0 1.0 5 Q99523 1 +Chondroitin sulfate proteoglycan metabolic process 0.4599496785518562 0.3307039164206947 0.7408681437337763 1.0 1.0 4 Q9NRB3 1 +Response to sodium arsenite 0.5524387031061858 0.3303957746739523 0.7411009337751733 1.0 1.0 3 P07196 1 +Regulation of cellular response to transforming growth factor beta stimulus 0.3598722469306033 0.3282399957253459 0.7427302093106785 1.0 1.0 13 Q92896,Q13526,O00560,Q9UNE7,P62942,Q8N3R9 6 +Myeloid leukocyte differentiation 0.3361216259016244 0.3259024971110317 0.7444981263387742 1.0 1.0 29 Q8N5M9,P04062,Q14739 3 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4582756897435227 0.3255146004591661 0.7447916342387497 1.0 1.0 4 P51572,Q9UHD9 2 +Regulation of dna dependent dna replication 0.3361755235490476 0.3248245988260958 0.7453138260420711 1.0 1.0 18 O75844,Q14691,Q9UJZ1,Q9Y248 4 +Positive regulation of g protein coupled receptor signaling pathway 0.5495803543674314 0.3230308356321261 0.7466718894231041 1.0 1.0 3 P49840,O14744 2 +Complement activation 0.5495803543674312 0.3230308356321257 0.7466718894231044 1.0 1.0 3 Q99623,Q07021 2 +Regulation of complement activation 0.5495803543674312 0.3230308356321257 0.7466718894231044 1.0 1.0 3 Q99623,Q07021 2 +Regulation of humoral immune response 0.5495803543674312 0.3230308356321257 0.7466718894231044 1.0 1.0 3 Q99623,Q07021 2 +Bone remodeling 0.4022107243409569 0.3219282117362726 0.7475070801035253 1.0 1.0 7 O14773 1 +Regulation of attachment of spindle microtubules to kinetochore 0.4101163770629135 0.3208830536549891 0.7482990166282806 1.0 1.0 6 Q8IXJ6 1 +Response to hydrogen peroxide 0.3276888802079294 0.3156291661006217 0.75228399716103 1.0 1.0 23 O95831 1 +Feeding behavior 0.4005153985775748 0.3149001349240766 0.7528374791574097 1.0 1.0 7 P05067,P50416,Q6Y7W6 3 +Small molecule biosynthetic process 0.3132863707209456 0.3127513674034644 0.7544695662234635 1.0 1.0 147 Q86SQ9,Q15125,P48449,Q16850,Q9P035,P04062,Q6P1A2,Q8NCG7,Q15392,P00813,Q53GQ0,Q9Y5Z9,O75208,Q9NP80,Q13126,O15269,Q9NZ01,P09455,Q9BV57,Q14739,Q13510,Q15800,P00374,Q92520,P09960,P16435,Q8NI60,Q9H7Z7,Q9UBX3,A1L0T0,Q9H2C2,O43175,P54646 33 +Purine deoxyribonucleotide catabolic process 0.420828572000972 0.3119504649232487 0.755078169285015 1.0 1.0 5 P16260 1 +Interleukin 6 production 0.3488076713754221 0.3114624538706758 0.7554490818030262 1.0 1.0 15 Q86UT6,P05067,P04062,Q08722 4 +Exonucleolytic catabolism of deadenylated mrna 0.3734757862838324 0.3114060809431362 0.7554919316481594 1.0 1.0 10 Q969T7,Q96B26 2 +Toll like receptor signaling pathway 0.3442184132427041 0.3112401032853715 0.7556180979383185 1.0 1.0 16 Q9NQC3,Q9NPR9 2 +Cellular response to manganese ion 0.6681168427594718 0.3110625081170566 0.7557531023832618 1.0 1.0 2 P05067 1 +Hindbrain morphogenesis 0.3993550971355724 0.3101120339247774 0.7564757613339286 1.0 1.0 7 P04062 1 +Positive regulation of deoxyribonuclease activity 0.6671845866998128 0.3089072260139175 0.7573920999002652 1.0 1.0 2 P23396 1 +Negative regulation of dna binding transcription factor activity 0.3213546930752136 0.3035907258408825 0.7614397180102812 1.0 1.0 20 P09601,O75381,Q96JB5,Q96J02,Q9UHD1,O76024,P19474 7 +Positive regulation of small gtpase mediated signal transduction 0.4510152991593577 0.3033876313016638 0.761594470559738 1.0 1.0 4 Q96AG4 1 +Negative regulation of glycogen metabolic process 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 1.0 2 P49840 1 +Regulation of glycogen starch synthase activity 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 1.0 2 P49840 1 +Response to interleukin 3 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 1.0 2 P49840 1 +Purine deoxyribonucleotide metabolic process 0.4053030489374545 0.3023455935341571 0.7623886250231804 1.0 1.0 6 P16260 1 +Forebrain cell migration 0.3615913988992875 0.3014356711248378 0.7630822968456983 1.0 1.0 11 Q96N66 1 +Positive regulation of small molecule metabolic process 0.3509149038721125 0.29959283459523 0.7644877504311587 1.0 1.0 14 P05067,Q92604,P31751,P33897,P50416,P00403,P16435,P54646 8 +Positive regulation of synaptic vesicle endocytosis 0.6615910503418359 0.2961565343041439 0.7671105412031813 1.0 1.0 2 O14656 1 +Female gamete generation 0.3233449267910415 0.2956479564198653 0.767498945941774 1.0 1.0 22 Q9Y2W6,Q8N2A8 2 +Regulation of short term neuronal synaptic plasticity 0.6612802983219475 0.2954573194854537 0.7676445518505548 1.0 1.0 2 Q15042 1 +Positive regulation of protein localization to cell surface 0.5385209965782206 0.2953088289451719 0.7677579725966421 1.0 1.0 3 Q92544 1 +Positive regulation of protein targeting to membrane 0.3869708714074694 0.2949526560283224 0.7680300465452872 1.0 1.0 8 P31751,P27105 2 +Schwann cell development 0.4030085788767036 0.2936171307319662 0.7690504840638686 1.0 1.0 6 P31751 1 +Neurotransmitter secretion 0.3311568136953495 0.2927890895573984 0.7696833682659006 1.0 1.0 18 P16615,P50897 2 +Body fluid secretion 0.3534138685760642 0.2924936617690931 0.7699092052867462 1.0 1.0 13 Q13505,P52789 2 +Reticulophagy 0.4147805675650527 0.2909436062006796 0.7710944502294543 1.0 1.0 5 Q9Y6I9,Q96HY6,Q86VR2 3 +Positive regulation of calcium ion transport 0.3406943576185213 0.2901466114532693 0.7717040779528248 1.0 1.0 16 O76024,P78417 2 +B cell differentiation 0.3593942511198393 0.2899780988150096 0.7718329927001999 1.0 1.0 11 Q5HYI8,P00813 2 +Microglial cell activation 0.6587942821628227 0.2898985675461961 0.7718938375264597 1.0 1.0 2 P05067 1 +Regulation of potassium ion import 0.5362138638483147 0.2896841820825837 0.7720578585729299 1.0 1.0 3 P05026,P54709 2 +Positive regulation of potassium ion import across plasma membrane 0.5362138638483147 0.2896841820825837 0.7720578585729299 1.0 1.0 3 P05026,P54709 2 +Suppression of viral release by host 0.401963715435818 0.2896660272069836 0.772071748889767 1.0 1.0 6 O60858 1 +Kinetochore assembly 0.4460216832674628 0.2885374947592615 0.7729353336342284 1.0 1.0 4 P50748 1 +Positive regulation of fatty acid transport 0.6581727781230665 0.2885186217984057 0.7729497781481389 1.0 1.0 2 P14174 1 +Positive regulation of dephosphorylation 0.3489061364331414 0.2882719855855262 0.7731385496215444 1.0 1.0 14 P04062,Q86XL3 2 +Deoxyribonucleoside triphosphate metabolic process 0.3685730379432984 0.2872970099893452 0.7738849118875284 1.0 1.0 10 Q9H773,Q7LG56 2 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.5348135197740326 0.2862974357936979 0.7746503219117138 1.0 1.0 3 P51572 1 +Regulation of monocyte chemotaxis 0.4133748055987453 0.2861299418530453 0.7747785995140579 1.0 1.0 5 Q4KMQ2,P07948,P09429,Q8NHP6 4 +Positive regulation of pattern recognition receptor signaling pathway 0.3769100403228578 0.2852569693590642 0.7754472772879906 1.0 1.0 9 Q9NQC3 1 +Camera type eye morphogenesis 0.3764006659417537 0.2829212403284175 0.7772372120792428 1.0 1.0 9 P54802,Q8NBN7 2 +Negative regulation of peptidyl serine phosphorylation 0.4440298507462608 0.2827002373425544 0.7774066342921533 1.0 1.0 4 Q07812,P63244,Q13610 3 +Pigment granule localization 0.4425425356981485 0.2783740390316885 0.780725246062594 1.0 1.0 4 Q15907,P62820 2 +Organic hydroxy compound transport 0.3285352885795293 0.2783176389466352 0.7807685369045614 1.0 1.0 28 O15118,Q9H2C2,P35610,P30536,Q8WTV0,Q6P1A2 6 +Low density lipoprotein particle clearance 0.3570815283896133 0.278003438743048 0.7810097190346665 1.0 1.0 11 P09601,Q92945,P35610,Q8WTV0,P38571 5 +Embryonic body morphogenesis 0.531240285980736 0.2777494978492186 0.7812046611202688 1.0 1.0 3 Q7Z460,Q9Y2X9 2 +Polyol metabolic process 0.3249228170701913 0.2776240067417264 0.7813010015999249 1.0 1.0 25 Q13510,P04062,P00374 3 +Regulation by virus of viral protein levels in host cell 0.4421369271550341 0.2771990923053227 0.7816272365668071 1.0 1.0 4 Q9P035 1 +Negative regulation of hormone secretion 0.3912347997144823 0.2771212858063178 0.7816869779355617 1.0 1.0 7 Q8N5M9 1 +Negative regulation of peptide secretion 0.3912347997144823 0.2771212858063178 0.7816869779355617 1.0 1.0 7 Q8N5M9 1 +Regulation of activin receptor signaling pathway 0.5306742546634164 0.2764079002738884 0.7822347894635526 1.0 1.0 3 P62942 1 +Activin receptor signaling pathway 0.5306742546634164 0.2764079002738884 0.7822347894635526 1.0 1.0 3 P62942 1 +Regulation of calcineurin mediated signaling 0.4096423017107405 0.2734787773094343 0.7844852040183001 1.0 1.0 5 Q9UHD1,P49841,Q8IWX8,P42345 4 +Negative regulation of translational elongation 0.6510254816656178 0.2729317678412401 0.7849056660520217 1.0 1.0 2 P49458 1 +Valine metabolic process 0.4091855017809398 0.2719435977342137 0.7856653878570232 1.0 1.0 5 A1L0T0 1 +Long term synaptic potentiation 0.3734948084833244 0.2696731269898407 0.7874117363806645 1.0 1.0 9 Q14168,Q9Y639,P05067,Q92542 4 +Insulin receptor signaling pathway 0.3231610335558894 0.2654131783027221 0.7906911852840353 1.0 1.0 25 P43490,Q9UQB8 2 +Positive regulation of leukocyte proliferation 0.3445256161842069 0.2638382876944445 0.7919045302457535 1.0 1.0 14 P49366,P00813,P30825,P23396,P04439 5 +Lens development in camera type eye 0.4062114944835306 0.2620199100566749 0.7933060922883055 1.0 1.0 5 Q99797 1 +Negative regulation of proteasomal protein catabolic process 0.326227976930445 0.2618253876642594 0.7934560651256646 1.0 1.0 18 Q96KB5,O00560,P46379,Q96HY6,O15372 5 +Apoptotic mitochondrial changes 0.3308122178181858 0.258773081763198 0.795810328244448 1.0 1.0 34 P45880,Q96A26,Q9H3K2,P52789 4 +Response to ketone 0.3327437880180489 0.2580727623787051 0.7963507521919513 1.0 1.0 39 P63096,P07196,P04062,Q13126,P30536,O95831,Q9H4A6,P16435,P54646 9 +Roof of mouth development 0.4353475544937669 0.2578458374873044 0.796525887039214 1.0 1.0 4 O95470 1 +Negative regulation of response to endoplasmic reticulum stress 0.3394886133354917 0.2577489545641888 0.7966006619319197 1.0 1.0 15 O43765,P55061,O60313,Q96HY6,Q6P1A2,P18031,O76024 7 +Programmed necrotic cell death 0.3393870596502812 0.2571727620781905 0.7970454097273265 1.0 1.0 15 Q13510 1 +Midbrain development 0.3160074662038015 0.2565382406946099 0.7975352563099747 1.0 1.0 21 Q8IXJ6,Q5T9L3,O14949 3 +Regulation of oxidative phosphorylation 0.3618462952351532 0.2548407324675314 0.7988461136817326 1.0 1.0 10 Q9BSK2,P14406,O14548 3 +Myelin maintenance 0.4031381859833796 0.2518963538988239 0.8011211779061038 1.0 1.0 5 P31751,P33897 2 +Lamellipodium morphogenesis 0.4027993779160124 0.2507886055290944 0.8019775515808316 1.0 1.0 5 O60749,Q9BR76,Q9Y6W5,Q9ULV4 4 +Neuron death 0.2973370716574233 0.2504979825060749 0.8022022647055493 1.0 1.0 71 Q9NR28,P09601,O75915,P05067,Q4ZIN3,P04062,Q96A26,Q99720,P31751,Q01105,O95831,P07196,Q9UHD1,Q9UMX5,O76024,Q15392,P50897 17 +Phagosome maturation 0.4315920398009867 0.2473998204950902 0.804598813093236 1.0 1.0 4 Q9BZG1,P61106,Q13636 3 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3286943569575323 0.2465261952554463 0.8052749291547738 1.0 1.0 17 Q96KB5,O00560,P46379,Q96HY6,O15372 5 +Vitamin k metabolic process 0.5176129249937329 0.2464159995791268 0.8053602221478842 1.0 1.0 3 Q8N0U8 1 +Positive regulation of leukocyte degranulation 0.4010559706591772 0.2451147911059206 0.8063675505639805 1.0 1.0 5 P11279,P51809 2 +Positive regulation of regulated secretory pathway 0.4010559706591772 0.2451147911059206 0.8063675505639805 1.0 1.0 5 P11279,P51809 2 +Purine deoxyribonucleoside triphosphate metabolic process 0.4305077492352849 0.2444188422913149 0.8069064501983705 1.0 1.0 4 P00813 1 +Peptidyl proline hydroxylation 0.3828497153617893 0.244060808365218 0.8071837252123031 1.0 1.0 7 P13674,O75718 2 +Negative regulation of mrna 3 end processing 0.4006220839813336 0.2437096228963258 0.8074557200613077 1.0 1.0 5 O75150,Q6PJT7,Q6PD62,P18615 4 +Isoleucine metabolic process 0.3887892990681023 0.241179335169452 0.8094161263773756 1.0 1.0 6 A1L0T0 1 +Skeletal muscle acetylcholine gated channel clustering 0.3996889580093336 0.2406970023800442 0.8097899624332021 1.0 1.0 5 Q96EY1,P49354,Q14696,O15258 4 +Nucleoside bisphosphate biosynthetic process 0.3276030836413743 0.2399948128091979 0.8103342778895928 1.0 1.0 33 Q53GQ0,Q8TB61,Q9UKU0,Q9UMR5,P16260,P50897 6 +Ribose phosphate biosynthetic process 0.2636362394902543 0.2397918118887141 0.8104916549773673 1.0 1.0 85 P00813,Q53GQ0,P16260,P24539,Q8TB61,Q9UKU0,P35610,O75964,P49915,Q9NZ01,Q9UMR5,P00846,Q9UJZ1,P50897 14 +Regulation of phospholipid biosynthetic process 0.3993635466255922 0.2396494207077085 0.8106020487500663 1.0 1.0 5 Q8NF37 1 +Nucleoside bisphosphate catabolic process 0.4286858411698566 0.2394456444007673 0.810760040054006 1.0 1.0 4 P35610 1 +Protein localization to condensed chromosome 0.3491217147563247 0.2374978603415945 0.8122705789265867 1.0 1.0 11 Q96DY7,P50748 2 +Negative regulation of rna catabolic process 0.3264339762577103 0.2369231718525185 0.8127163931633514 1.0 1.0 32 Q99729,Q14103,P35637,Q14011,Q92804,O60506,Q13151,P98175 8 +Glucose catabolic process 0.3656710357480845 0.2346790158841943 0.8144578758359777 1.0 1.0 9 P52789 1 +Response to phorbol 13 acetate 12 myristate 0.6314481044126885 0.2329534068142942 0.8157975863976576 1.0 1.0 2 P11802 1 +Lipid phosphorylation 0.6314481044126884 0.2329534068142933 0.8157975863976583 1.0 1.0 2 Q53H12 1 +Positive regulation of mast cell activation involved in immune response 0.6314481044126741 0.2329534068142659 0.8157975863976796 1.0 1.0 2 P51809 1 +Positive regulation of mast cell activation 0.6314481044126741 0.2329534068142659 0.8157975863976796 1.0 1.0 2 P51809 1 +Mitophagy 0.3297409485963111 0.226151295340198 0.8210837499428747 1.0 1.0 16 P21796,P27544,P12235,Q16543,P05141 5 +Regulation of jnk cascade 0.3410553607760365 0.22614865672078 0.8210858021022123 1.0 1.0 13 P05067,Q53EL6,O00560,Q13546,Q9UL54,Q96J02 6 +Positive regulation of t cell proliferation 0.3636118272377235 0.2256397856482938 0.8214815942627294 1.0 1.0 9 P23396,P04439,P30825 3 +Ribonucleoside monophosphate catabolic process 0.3949373727707195 0.2255572000622439 0.8215458323612361 1.0 1.0 5 P16260 1 +Purine nucleoside monophosphate catabolic process 0.3949373727707195 0.2255572000622439 0.8215458323612361 1.0 1.0 5 P16260 1 +Detection of light stimulus 0.5079013796585116 0.2253447530589065 0.8217110869315563 1.0 1.0 3 Q15555 1 +Phototransduction 0.5079013796585116 0.2253447530589065 0.8217110869315563 1.0 1.0 3 Q15555 1 +Nuclear membrane reassembly 0.340782007067208 0.2247144514146035 0.8222014215123206 1.0 1.0 13 Q86XL3,Q9NZZ3 2 +Centromere complex assembly 0.3626421570204915 0.2214088843297841 0.8247740753901283 1.0 1.0 9 Q6IPU0,P50748 2 +Endoplasmic reticulum plasma membrane tethering 0.505750699409397 0.220823354262834 0.8252299783588524 1.0 1.0 3 A0FGR8,Q9BSJ8 2 +Endoplasmic reticulum localization 0.505750699409397 0.220823354262834 0.8252299783588524 1.0 1.0 3 A0FGR8,Q9BSJ8 2 +Regulation of b cell apoptotic process 0.3928278910099663 0.2189451308252296 0.8266927899299241 1.0 1.0 5 P14174,P00813 2 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.5046625800860169 0.2185560184340628 0.8269959166571057 1.0 1.0 3 P98194 1 +Negative regulation of helicase activity 0.5041913642288115 0.2175783657878537 0.8277576422669415 1.0 1.0 3 P49736 1 +Fatty acid beta oxidation 0.327114109952376 0.2170924979140454 0.8281362603555891 1.0 1.0 38 Q9BWD1,P23786,O14975,Q15067,P50542,O15254,P35610,Q2T9J0,P49748,P50416,P31751,O14734,P33897,Q16134,Q709F0 15 +Positive regulation of neutrophil migration 0.392223950233277 0.2170646642256677 0.8281579512853834 1.0 1.0 5 Q07021,O00429,Q8NE86,Q8NHP6 4 +Positive regulation of granulocyte chemotaxis 0.392223950233277 0.2170646642256677 0.8281579512853834 1.0 1.0 5 Q07021,O00429,Q8NE86,Q8NHP6 4 +Pyrimidine nucleobase catabolic process 0.4202148172011614 0.2169198802316881 0.8282707842751129 1.0 1.0 4 Q02252 1 +Positive regulation of amine transport 0.4201044848068506 0.2166330705458911 0.8284943111168408 1.0 1.0 4 Q15041,P55011 2 +Positive regulation of amino acid transport 0.4201044848068506 0.2166330705458911 0.8284943111168408 1.0 1.0 4 Q15041,P55011 2 +Protein localization to chromosome centromeric region 0.3420395037258764 0.2155296584785707 0.8293543912458858 1.0 1.0 12 Q96DY7,P50748 2 +Establishment of protein localization to plasma membrane 0.3158023875359145 0.2152208163078915 0.8295951621242346 1.0 1.0 25 Q4J6C6,Q9H8Y8,P98194,Q8N2H4,P61026,Q9H4A6 6 +Regulation of ion transport 0.2729378966669598 0.2150951920926795 0.8296931023346876 1.0 1.0 79 P55061,P05067,Q4KMQ2,P30536,Q15907,P62942,P21796,P27105,O75844,P05023,Q9UHD1,O76024,P20020,Q9NVV0,Q13546,Q9Y696,P08183,P78417,Q15041,Q9BVC6,O75915 21 +Carnitine metabolic process 0.391424317682241 0.2145835374879859 0.8300920301385455 1.0 1.0 5 P23786 1 +Protein ufmylation 0.4187032158137193 0.2130053849914451 0.8313227624524515 1.0 1.0 4 Q96JB5,Q96HY6 2 +Negative regulation of viral transcription 0.4986045601220905 0.2061829339346579 0.8366480181943192 1.0 1.0 3 O60858 1 +Medium chain fatty acyl coa metabolic process 0.616842759477947 0.2057818092376495 0.8369613512236294 1.0 1.0 2 O00154 1 +Sulfur amino acid metabolic process 0.3400751164476849 0.2056169268387982 0.8370901543410321 1.0 1.0 12 Q13126 1 +Positive regulation of myeloid leukocyte differentiation 0.498212174145942 0.2053962098206241 0.8372625812776442 1.0 1.0 3 O00165 1 +Positive regulation of histone ubiquitination 0.4979794839913058 0.2049305199541969 0.8376264097495092 1.0 1.0 3 O60341,Q6PD62 2 +Tolerance induction 0.4976686353745812 0.2043093949131799 0.8381117287387045 1.0 1.0 3 P09429,Q96J02 2 +Secretory granule organization 0.6155997513983944 0.203575528175951 0.838685218347375 1.0 1.0 2 P22059 1 +Negative regulation of lipid storage 0.6152889993785065 0.2030265713846143 0.8391142637345765 1.0 1.0 2 Q9BZF1 1 +Negative regulation of sequestering of triglyceride 0.6152889993785065 0.2030265713846143 0.8391142637345765 1.0 1.0 2 Q9BZF1 1 +Response to zinc ion 0.3875094199768782 0.2025800548260168 0.8394632806999618 1.0 1.0 5 P09960 1 +Positive regulation of mitochondrial fission 0.3647771323509195 0.2019921816028727 0.8399228363821873 1.0 1.0 8 Q9GZY8,Q9NX47,Q96HS1,O94830 4 +Regulation of water loss via skin 0.3857086199714697 0.1971397599272181 0.8437181699813552 1.0 1.0 5 P04062 1 +Nucleoside monophosphate catabolic process 0.3761323482921034 0.1970893488730279 0.8437576183247417 1.0 1.0 6 P16260 1 +Schwann cell differentiation 0.3700292703377907 0.1956647800835026 0.8448725529313568 1.0 1.0 7 P31751 1 +Positive regulation of calcium ion import 0.6109384711000727 0.1954510495700531 0.8450398553617446 1.0 1.0 2 Q9NRA0 1 +Nucleobase containing small molecule biosynthetic process 0.3691782914221954 0.1925501210688216 0.8473113114057558 1.0 1.0 7 Q13126 1 +Glycosyl compound biosynthetic process 0.3691782914221954 0.1925501210688216 0.8473113114057558 1.0 1.0 7 Q13126 1 +Deoxyribonucleoside monophosphate metabolic process 0.3559025745239185 0.1924704537134801 0.8473737097318377 1.0 1.0 9 P16260 1 +Regulation of cytosolic calcium ion concentration 0.3093162543045309 0.1914661509492926 0.8481603975567586 1.0 1.0 23 P55061,Q9NVV0,Q9Y639,P51572,P78417,P62942,P20020 7 +Translational readthrough 0.6081417029210796 0.1906894781800424 0.8487688826245747 1.0 1.0 2 P38919 1 +Autophagy of mitochondrion 0.3218589140249738 0.1887675674226798 0.8502749922513984 1.0 1.0 35 O00165,P52789,P04062,P21796,P27544,Q9BWH2,P12235,P30536,P05141,Q9H300 10 +Lipid translocation 0.4896178091182699 0.1886171683732961 0.8503928759263215 1.0 1.0 3 P08183 1 +Rna guanine n7 methylation 0.606587942821639 0.1880808482840143 0.8508132740289127 1.0 1.0 2 O43709 1 +Regulation of receptor binding 0.488826089523294 0.1871152197057119 0.851570295309253 1.0 1.0 3 P16615 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.3813374805598703 0.184150833595614 0.8538951288684768 1.0 1.0 5 Q99729,P11940,Q9Y5S9,P38919 4 +Fatty acid homeostasis 0.4060896871889246 0.1816176650990579 0.8558827846675683 1.0 1.0 4 P54646 1 +Regulated exocytosis 0.3194345860655426 0.1813569805297237 0.8560873834597684 1.0 1.0 33 P09601,Q4J6C6,Q68EM7,P11279,P49755,O43760,P16615,Q15907 8 +Cellular response to reactive oxygen species 0.3141244335985947 0.1783524574090959 0.8584461840928088 1.0 1.0 28 Q99720,O95831 2 +L aspartate transmembrane transport 0.40360696517412 0.1757132331979636 0.8605192384748703 1.0 1.0 4 Q9H936,O75746,Q9UJS0 3 +Sulfur compound metabolic process 0.27322006736804 0.1750435583952976 0.8610454072696003 1.0 1.0 104 O60725,Q53GQ0,Q9UBX3,Q8TB61,Q8NCH0,Q9UKU0,Q13126,O75027,Q9NZ01,O43175,O43505,P78417,Q9UMR5,Q9BV57,P50897 15 +Positive regulation of stress activated protein kinase signaling cascade 0.3278440539775241 0.1743326226236851 0.8616040626292583 1.0 1.0 14 P05067,O00560,Q13546,Q9UL54,O75915 5 +Reactive oxygen species biosynthetic process 0.3308727242362809 0.1737911547314972 0.8620295961120765 1.0 1.0 13 O75027,Q9BSK2,Q15067,P51790 4 +Negative regulation of response to external stimulus 0.3219000118242175 0.1720859138350727 0.8633699866939208 1.0 1.0 45 O43657,P00813,Q86UT6,Q96KB5,Q8IXJ6,P28070,P04062,P80303,Q6P1A2,Q96G23,Q9UMX5 11 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.315869302031886 0.1717223051579378 0.8636558493171624 1.0 1.0 17 O43159,P61978,P14174,P17844,P46379,Q7LG56,O96017,Q9BVC6 8 +Negative regulation of neuron projection development 0.3111353414547556 0.1705147634681465 0.8646053248131345 1.0 1.0 18 Q9NQX7,Q9NQC3,Q9NR77,Q96G23 4 +Response to gamma radiation 0.3107138740402401 0.1680486155274362 0.8665450332104707 1.0 1.0 18 O75844 1 +Macrophage chemotaxis 0.3757117174348527 0.167893923335051 0.8666667307472427 1.0 1.0 5 Q9BW27 1 +Macrophage migration 0.3757117174348527 0.167893923335051 0.8666667307472427 1.0 1.0 5 Q9BW27 1 +Amyloid beta clearance 0.3495249860359084 0.1658738309492706 0.86825624205239 1.0 1.0 9 Q16850 1 +Adiponectin activated signaling pathway 0.4771526266708216 0.1658338814780805 0.8682876817180039 1.0 1.0 3 P67870,P33121 2 +Positive regulation of cytokine production involved in inflammatory response 0.4771526266708191 0.1658338814780759 0.8682876817180074 1.0 1.0 3 P40763,O60684 2 +Protein lipid complex assembly 0.3745903231973175 0.1647163942688037 0.8691672124812988 1.0 1.0 5 P35610 1 +Negative regulation of b cell apoptotic process 0.4764385668592927 0.1645848454353122 0.8692707601292426 1.0 1.0 3 P00813 1 +Nucleoside phosphate biosynthetic process 0.2672572827926518 0.1642836196066755 0.8695078761546353 1.0 1.0 97 P00813,Q53GQ0,P16260,Q7LG56,P24539,Q8TB61,Q9UKU0,P35610,O75964,P49915,Q9NZ01,P31350,Q9UMR5,P00846,P43490,Q9UJZ1,P50897 17 +Nuclear ncrna surveillance 0.3658475058734964 0.1632194465980656 0.8703456553518045 1.0 1.0 6 Q96B26 1 +Regulation of biological process involved in symbiotic interaction 0.3548404354936175 0.1630970744830197 0.8704420031809448 1.0 1.0 8 Q9BTY2 1 +Regulation of phagocytosis 0.3220599840045202 0.1621309767321017 0.871202712999628 1.0 1.0 15 Q4KMQ2,Q08722,Q8WTV0 3 +Response to arsenic containing substance 0.3278370901821896 0.158629264525015 0.8739609709662268 1.0 1.0 13 P09601,P78417,P07196 3 +Dna unwinding involved in dna replication 0.3132052776937969 0.1567027079994629 0.8754791527753392 1.0 1.0 17 P25205,P49736,Q9Y248,O75419 4 +Ventral spinal cord development 0.3945895522387964 0.1550428952901454 0.8767875006023802 1.0 1.0 4 Q14203,Q8NCM8,Q6Y7W6 3 +Visual behavior 0.3632628399051609 0.1549985548587094 0.8768224565933345 1.0 1.0 6 Q9Y639,P05067 2 +3 utr mediated mrna destabilization 0.3632593855844681 0.1549876480326299 0.8768310550785985 1.0 1.0 6 Q92945,Q9HCE1 2 +Negative regulation of cell killing 0.4704613210002644 0.1543687537357047 0.8773189892259079 1.0 1.0 3 P04439 1 +Fatty acid catabolic process 0.3189706438141373 0.1503319601793931 0.8805027189259056 1.0 1.0 46 Q9BWD1,P23786,O14975,A1L0T0,Q15067,Q8NCC3,P50542,O15254,P35610,Q2T9J0,P49748,P50416,P31751,O14734,P33897,Q16134,Q709F0 17 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.3692068429237858 0.149758766818063 0.8809549417095339 1.0 1.0 5 P11177,O95563,P08559,P09622 4 +Regulation of protein dephosphorylation 0.3043815236732825 0.1497290298230938 0.8809784038698085 1.0 1.0 24 P04062,P62942,Q86XL3 3 +Endoplasmic reticulum to cytosol transport 0.3229555125621957 0.1492889548500845 0.8813256303597088 1.0 1.0 14 Q9UBV2,Q9BUN8,P51572,Q13438,Q9Y679 5 +Protein destabilization 0.3382875978353236 0.1476617881379184 0.8826096896243629 1.0 1.0 10 Q9BUN8,P54725 2 +Pattern specification process 0.3117053646311875 0.1470375635076339 0.8831023711417887 1.0 1.0 30 Q9ULK5,Q9Y2W6,Q15363,Q8N2A8 4 +Plasma lipoprotein particle clearance 0.3278605521206864 0.1458418719665476 0.8840462202270458 1.0 1.0 12 P09601,Q92945,P35610,Q8WTV0,P38571 5 +Spermatid nucleus differentiation 0.464407833385152 0.1444585772466914 0.8851383638672077 1.0 1.0 3 Q96SB4,P26583 2 +Response to hepatocyte growth factor 0.3592991059802147 0.1426256338001977 0.8865858516028291 1.0 1.0 6 Q8IXJ6,P46108 2 +Cellular modified amino acid metabolic process 0.3085484700150461 0.1423219389565127 0.8868257181337 1.0 1.0 59 Q9BVG9,O60725,Q9H7Z7,P23786,Q9UHG3,Q9H2D1,Q8NCC3,Q8NBM8,P78417,P16435,P00374 11 +Positive regulation of ubiquitin dependent protein catabolic process 0.3086495810690165 0.1418707957788206 0.8871820625435303 1.0 1.0 28 O43765,Q8IXJ6,P51572,P45974,P04062,Q96JB5,Q96HY6,Q9UHD9,Q9BW61,O60826,P48729,P54725 12 +Negative regulation of cell growth 0.3014506236015656 0.1410616663070558 0.8878212266358332 1.0 1.0 23 Q16576,Q9P0J0,P49840,Q9NQC3,Q8N0X7,O94826,O60271,P50897 8 +Circulatory system process 0.28748930249208 0.1400335633118554 0.8886334719609421 1.0 1.0 71 P42892,P00813,P30825,O75844,P42785,P05023,P10253,Q9HB40,P08183,P11166,P16615,P78417,Q9NZ08,P53985,Q9UIQ6 15 +Rig i signaling pathway 0.3288596939187598 0.1399945449165909 0.8886643004702273 1.0 1.0 11 Q86UT6 1 +Regulation of anaphase promoting complex dependent catabolic process 0.574269732753275 0.1397416802041936 0.8888640934466159 1.0 1.0 2 P24941 1 +Cellular response to acid chemical 0.3239247535253128 0.1394113097108889 0.8891251357759695 1.0 1.0 13 Q99729,Q14103,O00410,Q9UQB8 4 +Regulation of extracellular matrix organization 0.3868159203980047 0.1382137830417802 0.8900714623516786 1.0 1.0 4 Q8NBJ5,Q7Z460,O75122 3 +Positive regulation of extracellular matrix organization 0.3868159203980047 0.1382137830417802 0.8900714623516786 1.0 1.0 4 Q8NBJ5,Q7Z460,O75122 3 +Regulation of amyloid fibril formation 0.36454121306376 0.1371989477436983 0.8908735426248802 1.0 1.0 5 Q9UHV9,P05067,O60925,P61758 4 +Meiotic cytokinesis 0.4597451041342972 0.1371244336916073 0.8909324395985605 1.0 1.0 3 P61160,Q12768 2 +Collateral sprouting 0.4592145342278219 0.136306365305783 0.891579092065057 1.0 1.0 3 P05067 1 +Protein refolding 0.3279734264253797 0.1359341211499588 0.8918733610468781 1.0 1.0 11 P62942 1 +Regulation of protein deacetylation 0.3277927492729899 0.1351086094170713 0.8925260032658682 1.0 1.0 11 O43823,Q9ULX6,P54646 3 +Maintenance of organelle location 0.5705407085146175 0.1348833379019665 0.8927041135794065 1.0 1.0 2 P43034 1 +Maintenance of centrosome location 0.5705407085146175 0.1348833379019665 0.8927041135794065 1.0 1.0 2 P43034 1 +Pyrimidine containing compound catabolic process 0.3472205357825532 0.1345459995158064 0.8929708393786338 1.0 1.0 8 Q9H773 1 +Epithelial structure maintenance 0.5699192044748413 0.1340878349319907 0.893333119089174 1.0 1.0 2 Q9Y3F4 1 +Rrna 5 end processing 0.3633250888129992 0.1339875621001374 0.8934124097525775 1.0 1.0 5 Q86U38 1 +Inorganic ion import across plasma membrane 0.356018872970942 0.1326044713410252 0.8945061960347027 1.0 1.0 6 P05026,P05023,P55011 3 +Hydrogen peroxide biosynthetic process 0.4559162244022595 0.131296225058663 0.8955409779086194 1.0 1.0 3 Q15067 1 +Regulation of cardiac muscle cell proliferation 0.454460677649995 0.1291265145400455 0.897257542067947 1.0 1.0 3 Q16539,P06493 2 +Positive regulation of cardiac muscle cell proliferation 0.454460677649995 0.1291265145400455 0.897257542067947 1.0 1.0 3 Q16539,P06493 2 +T cell selection 0.4535281317998237 0.1277496764639966 0.8983470759988632 1.0 1.0 3 P40763,P42345 2 +Regulation of endoplasmic reticulum tubular network organization 0.3534443197858141 0.1248798413138907 0.900618677726694 1.0 1.0 6 Q15041 1 +Rrna 3 end processing 0.3496094613838174 0.1245630060319644 0.900869517140797 1.0 1.0 7 Q96B26 1 +Meiosis i cell cycle process 0.3073182702317595 0.124205726359144 0.9011523883715772 1.0 1.0 17 P46379,Q9BTX1 2 +Negative regulation of lymphocyte mediated immunity 0.4501420879621965 0.1228373332319268 0.9022359104708496 1.0 1.0 3 P04439 1 +Water homeostasis 0.3439993634285053 0.1228270343174665 0.9022440660583247 1.0 1.0 8 P04062,O76024 2 +Inositol phosphate catabolic process 0.3589775827035075 0.1227207407176833 0.9023282392942584 1.0 1.0 5 Q10713 1 +Positive regulation of myotube differentiation 0.558110627719093 0.1197364761712429 0.9046919044049502 1.0 1.0 2 Q16539 1 +Cellular response to leucine 0.5581106277190909 0.1197364761712406 0.904691904404952 1.0 1.0 2 Q9P2J5 1 +Regulation of nik nf kappab signaling 0.3136695943076605 0.1187140667680107 0.9055018916919946 1.0 1.0 15 O43657,P05067,Q53EL6 3 +Morphogenesis of a branching structure 0.3020146996463808 0.1182796753225143 0.9058460610861758 1.0 1.0 18 Q9NQC3,Q15363 2 +Sodium ion transport 0.2977841371447907 0.1182215165276626 0.905892141783872 1.0 1.0 23 Q4KMQ2,Q9H2J7,P05023,Q9Y6M7,Q9UHD1,P27105 6 +Positive regulation of transporter activity 0.2943328466766909 0.1181110708657465 0.9059796515730144 1.0 1.0 21 Q03164,P08183 2 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.3765547263681538 0.1174256943033452 0.9065227238106672 1.0 1.0 4 P78406,P57740,O75694 3 +Monocarboxylic acid transport 0.3422240076351515 0.1164597460568889 0.9072881869540236 1.0 1.0 8 Q9NP80 1 +Alpha linolenic acid metabolic process 0.3564183741579672 0.1162457731310843 0.9074577609108684 1.0 1.0 5 O14734,O95864 2 +Positive regulation of ruffle assembly 0.4451352191482793 0.1158224139861541 0.907793286272052 1.0 1.0 3 Q7L576,Q8NCA5 2 +Oxidative rna demethylation 0.5543816034804356 0.1155018075087103 0.9080473878817736 1.0 1.0 2 Q6P6C2 1 +Oxidative demethylation 0.5543816034804356 0.1155018075087103 0.9080473878817736 1.0 1.0 2 Q6P6C2 1 +Physiological cardiac muscle hypertrophy 0.3753109452736221 0.115017077497048 0.9084315859902724 1.0 1.0 4 P49840,O94826,P11413 3 +Regulation of calcium ion transport 0.3078922247684285 0.1145952847397138 0.9087659173203464 1.0 1.0 31 P62942,P21796,O76024,P78417 4 +Organophosphate biosynthetic process 0.3121002309062702 0.1145671572303131 0.9087882129861032 1.0 1.0 168 Q86SQ9,Q9HBU6,Q8TB61,Q8NF37,O95674,P35610,Q9NUQ2,Q9NPH0,Q6P1A2,P00846,P50897,Q8WUK0,Q53GQ0,P00813,Q9UKU0,O15269,P31350,O75964,Q9NZ01,Q9UMR5,O14735,Q9C0D9,Q96N66,Q9Y2B2,Q9BVG9,Q10713,P24539,Q86YN1,P49915,P16260,O43292,Q9UJZ1,Q7LG56,P35790,P43490,Q9H490,Q9UG56 37 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3016267727442104 0.1135858705050556 0.9095660885576616 1.0 1.0 26 O43765,Q8IXJ6,P51572,P45974,P04062,Q96HY6,Q9UHD9,Q9BW61,P54725 9 +Telomere maintenance via recombination 0.3552099533436966 0.1132292496765707 0.9098488068920136 1.0 1.0 5 Q96SB8,Q8IY18,P18887,Q96MF7 4 +Chromosome attachment to the nuclear envelope 0.5506525792417695 0.1114073614955784 0.911293322773466 1.0 1.0 2 O94901 1 +Negative regulation of nuclear division 0.300557693931007 0.1101648870328849 0.9122786088241056 1.0 1.0 18 Q96DY7,O43264,P50748 3 +Activation of protein kinase c activity 0.5494095711622257 0.1100734299869656 0.9123511398889737 1.0 1.0 2 Q99623 1 +Regulation of phospholipase c activity 0.5494095711622257 0.1100734299869656 0.9123511398889737 1.0 1.0 2 Q99623 1 +Activation of phospholipase c activity 0.5494095711622257 0.1100734299869656 0.9123511398889737 1.0 1.0 2 Q99623 1 +Plasma membrane tubulation 0.3530326594090104 0.1078606928118113 0.9141061977497866 1.0 1.0 5 Q9UNF0,Q9UKS6,P50570,Q9Y371 4 +Positive regulation of potassium ion transmembrane transporter activity 0.3700248756218865 0.10504963656432 0.9163364222927056 1.0 1.0 4 P05026,P50570,P54709 3 +Negative regulation of programmed necrotic cell death 0.3695649859051751 0.1042030901859683 0.9170081817112494 1.0 1.0 4 P12235 1 +Negative regulation of necrotic cell death 0.3695649859051751 0.1042030901859683 0.9170081817112494 1.0 1.0 4 P12235 1 +Amyloid fibril formation 0.3383818716884021 0.1029072726222228 0.9180365656305314 1.0 1.0 8 P62942,P05067 2 +I kappab kinase nf kappab signaling 0.3120639234786851 0.1023930594348903 0.9184446924870732 1.0 1.0 49 O43657,Q86UT6,P98194,O60858,Q9Y3E0,Q8TB61,Q5T9L3,Q86UE4,P62942,Q8TCD1 10 +Intestinal absorption 0.3273437001809659 0.1018195970896156 0.9188998702631592 1.0 1.0 10 Q6P1A2,Q8WTV0 2 +Positive regulation of rna export from nucleus 0.3501610462160421 0.1009116712399859 0.9196205780953364 1.0 1.0 5 Q07666 1 +Positive regulation of nucleobase containing compound transport 0.3501610462160421 0.1009116712399859 0.9196205780953364 1.0 1.0 5 Q07666 1 +Purine nucleobase biosynthetic process 0.3270569987117989 0.1006559299532103 0.9198235964297709 1.0 1.0 10 P49915 1 +Spermidine metabolic process 0.4330121230960584 0.100054178065516 0.9203013133202308 1.0 1.0 3 P49366,Q9H2H9 2 +Cellular carbohydrate catabolic process 0.3064064812933065 0.09926701343094 0.920926268493104 1.0 1.0 16 Q14108,Q9NUJ1 2 +Bleb assembly 0.3668297294204843 0.0992363775635093 0.9209505922776264 1.0 1.0 4 Q9NR77 1 +Skeletal system morphogenesis 0.3025182449860225 0.0984547406934803 0.9215712089843868 1.0 1.0 17 O75844,O95470 2 +Negative regulation of defense response 0.3053379692898154 0.0977581424814419 0.9221243455812492 1.0 1.0 31 O43657,P00813,Q86UT6,Q96KB5,Q8IXJ6,P28070,P04062,Q6P1A2 8 +Negative regulation of cell adhesion mediated by integrin 0.5360472343070359 0.0966887343920959 0.9229735865635252 1.0 1.0 2 Q06124 1 +Negative regulation of amyloid fibril formation 0.3644278606965117 0.0949713556294439 0.9243375789532442 1.0 1.0 4 Q9UHV9,O60925,P61758 3 +Mannosylation 0.3255419530289314 0.094539335403024 0.9246807372198638 1.0 1.0 10 O43505,Q9BV10 2 +Negative regulation of translational initiation 0.3401805166510978 0.094453697950717 0.9247487616267538 1.0 1.0 7 P40429,P05198,Q9BWF3,Q06787,P60228,Q6PKG0 6 +Response to corticosterone 0.427818817917767 0.0938185738522295 0.9252532769614406 1.0 1.0 3 P07196 1 +Cell migration involved in gastrulation 0.4274168479950359 0.093348729626805 0.9256265204133428 1.0 1.0 3 Q9HCM4,Q4VCS5 2 +Positive regulation of membrane potential 0.3424381413422787 0.0932877405143445 0.925674971262502 1.0 1.0 6 P31751 1 +Positive regulation of muscle cell apoptotic process 0.3397517566547079 0.0931277774113641 0.925802050141153 1.0 1.0 7 P98175 1 +Positive regulation of hexokinase activity 0.4271059993783128 0.0929866472547084 0.9259141692059962 1.0 1.0 3 P49792,Q9UNI6 2 +Regulation of extracellular matrix assembly 0.5310752019888234 0.0921435306169147 0.9265840031111848 1.0 1.0 2 Q7Z460 1 +Positive regulation of basement membrane assembly involved in embryonic body morphogenesis 0.5310752019888234 0.0921435306169147 0.9265840031111848 1.0 1.0 2 Q7Z460 1 +Positive regulation of extracellular matrix assembly 0.5310752019888234 0.0921435306169147 0.9265840031111848 1.0 1.0 2 Q7Z460 1 +Gmp biosynthetic process 0.3161218382926961 0.0917129542352544 0.926926104780782 1.0 1.0 12 P49915 1 +Gmp metabolic process 0.3011533582653642 0.091260516906734 0.9272855899709036 1.0 1.0 17 P16260,P49915 2 +Regulation of map kinase activity 0.3011030473500576 0.0909964401093 0.9274954197035434 1.0 1.0 17 Q53EL6,P14174,P04062,P23396,Q96JB5,Q99816,O14964 7 +Positive regulation of histone phosphorylation 0.529521441889384 0.0907702298419475 0.927675165517502 1.0 1.0 2 Q06787 1 +Positive regulation of cyclase activity 0.5295214418893824 0.0907702298419461 0.9276751655175032 1.0 1.0 2 Q16539 1 +Sertoli cell development 0.5288999378496062 0.0902271188665878 0.9281067344737666 1.0 1.0 2 P51659 1 +Regulation of mitotic centrosome separation 0.4246192104445179 0.0901292500138832 0.9281845056548296 1.0 1.0 3 P52732,Q9UNZ2 2 +Negative regulation of epithelial cell apoptotic process 0.3411324425621288 0.0896968519426958 0.92852811764537 1.0 1.0 6 O76024 1 +Negative regulation of mitophagy 0.4233758159776286 0.0887266206295259 0.9292991757641448 1.0 1.0 3 P49815,Q9NQ88 2 +Positive regulation of lymphocyte apoptotic process 0.4233758159776227 0.0887266206295195 0.92929917576415 1.0 1.0 3 Q07812,Q9Y255 2 +Protein heterooligomerization 0.3339238017339918 0.087580035444327 0.9302104706031344 1.0 1.0 8 P31350,Q9NSD9 2 +Cellular hyperosmotic response 0.3399267984984862 0.086411190091871 0.931139551797558 1.0 1.0 6 O95202,P11166 2 +Pteridine containing compound metabolic process 0.291614593988946 0.0850386369306295 0.9322306741153152 1.0 1.0 19 Q9H2D1 1 +Response to interleukin 4 0.337068160597568 0.0849160414510953 0.9323281386167448 1.0 1.0 7 P12268,P11802,P33993,P49736,P39023,P08238 6 +Astrocyte development 0.3432442579536812 0.0847933619616297 0.9324256709225054 1.0 1.0 5 P08670 1 +Regulation of protein targeting to membrane 0.3283687403071061 0.0836925988032746 0.9333008418000468 1.0 1.0 9 P31751,P27105 2 +Striated muscle cell proliferation 0.3363134898959011 0.0826340025702753 0.9341425635821954 1.0 1.0 7 Q8NDZ4,P10644 2 +Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.3569651741293457 0.0822935400545022 0.9344132912878208 1.0 1.0 4 P49840,P49841,Q9UII2 3 +Immune response regulating signaling pathway 0.3057912329545615 0.0807002328563195 0.9356803516295982 1.0 1.0 55 O43657,P00813,Q86UT6,Q08722,Q9NPR9,Q9NUD5,P51812,P46379,Q9NQC3,Q9UJZ1 10 +Ensheathment of neurons 0.2945723794402651 0.0790779216357351 0.9369706444922756 1.0 1.0 25 Q96PU8,Q8IXJ6,Q9NR77,P31751,P33897,Q92542,Q8N3R9,O15228 8 +T cell homeostasis 0.3369632856253825 0.0784583229665418 0.9374634814395596 1.0 1.0 6 Q07812,Q99576,Q96EY1,O95067,P62753 5 +Negative regulation of leukocyte chemotaxis 0.4131178116257407 0.0778080611602984 0.937980734013402 1.0 1.0 3 P14174,P30046 2 +Positive regulation of production of mirnas involved in gene silencing by mirna 0.3396578538102568 0.0767835196621649 0.938795761433424 1.0 1.0 5 P04637,P17844,Q13546,Q02750 4 +Neuron projection guidance 0.2891910042009068 0.0767664148498902 0.9388093689358964 1.0 1.0 22 P42892,O00264,Q13509 3 +Negative regulation of ion transmembrane transporter activity 0.3125484608665056 0.0759411016844378 0.9394659568379338 1.0 1.0 12 P78417 1 +Meiotic chromosome segregation 0.286705230096321 0.072901239868817 0.9418847072982884 1.0 1.0 21 Q92791,Q9BTX1,P46379 3 +Chemokine c x c motif ligand 2 production 0.5049720323182251 0.0719001109940016 0.9426814017195142 1.0 1.0 2 P14174 1 +Positive regulation of vascular endothelial cell proliferation 0.5049720323182251 0.0719001109940016 0.9426814017195142 1.0 1.0 2 P40763 1 +Positive regulation of chemokine c x c motif ligand 2 production 0.5049720323182251 0.0719001109940016 0.9426814017195142 1.0 1.0 2 P14174 1 +Vascular endothelial cell proliferation 0.5049720323182251 0.0719001109940016 0.9426814017195142 1.0 1.0 2 P40763 1 +Negative regulation of interferon gamma production 0.504972032318225 0.0719001109940013 0.9426814017195144 1.0 1.0 2 Q07021 1 +Necrotic cell death 0.2934221273278716 0.0714036449086021 0.9430765087988662 1.0 1.0 18 Q13510,P12235 2 +Natural killer cell degranulation 0.4051212570163902 0.0700855258428785 0.9441255870759764 1.0 1.0 3 P11279 1 +Natural killer cell activation involved in immune response 0.4051212570163902 0.0700855258428785 0.9441255870759764 1.0 1.0 3 P11279 1 +Negative regulation of proteolysis 0.3026279045798981 0.0690295194247761 0.9449661224330128 1.0 1.0 57 Q96K76,P05067,P19474,Q96KB5,O00560,P49755,P51812,P46379,Q96HY6,Q15041,O15372,Q9BXS4,Q9NWS0,Q15418,Q96KC8,P16435,Q15392 17 +Regulation of histone h2b ubiquitination 0.4978247358607969 0.0673459069916504 0.946306331323738 1.0 1.0 2 Q6PD62 1 +Dendritic cell differentiation 0.4975139838409099 0.0671568849116727 0.9464568084524964 1.0 1.0 2 P09429 1 +Regulation of metallopeptidase activity 0.4015031140567731 0.0668116936965999 0.9467316139882992 1.0 1.0 3 Q96HY6 1 +Positive regulation of chromatin binding 0.4968924798011324 0.0667810462284485 0.946756012638804 1.0 1.0 2 O60341 1 +Positive regulation of endocytosis 0.288315875990593 0.0667599540358517 0.9467728043007486 1.0 1.0 19 P61978,Q4KMQ2,Q99816,O75955,P50897 5 +Nucleotide excision repair dna gap filling 0.4959602237414697 0.0662227778901035 0.9472004624430086 1.0 1.0 2 Q07864 1 +Positive regulation of glucokinase activity 0.4956494717215816 0.0660381459454758 0.9473474556510428 1.0 1.0 2 Q9UNI6 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.3321074252084295 0.0658098389005291 0.947529222909704 1.0 1.0 6 Q53EL6 1 +Reelin mediated signaling pathway 0.3994404724899039 0.0650054797060217 0.9481696373106632 1.0 1.0 3 P46108,P43034 2 +Positive regulation of protein acetylation 0.3224648000329624 0.0625607533197534 0.9501162824811866 1.0 1.0 9 P54646,Q9NWS0 2 +Regulation of cardiac muscle contraction by calcium ion signaling 0.3294008055449725 0.0622952469301466 0.9503277135275776 1.0 1.0 7 P78417 1 +Positive regulation of fat cell differentiation 0.3306460585945506 0.0620971253546298 0.9504854862170578 1.0 1.0 6 O96017,Q96A49,Q86X55 3 +Spinal cord motor neuron differentiation 0.394466894622328 0.0608266503043454 0.9514972657399736 1.0 1.0 3 Q8NCM8,Q6Y7W6 2 +Cell differentiation in spinal cord 0.394466894622328 0.0608266503043454 0.9514972657399736 1.0 1.0 3 Q8NCM8,Q6Y7W6 2 +Response to thyroxine 0.3941565547850282 0.0605740620854539 0.9516984310378388 1.0 1.0 3 O94826 1 +Response to l phenylalanine derivative 0.3941565547850282 0.0605740620854539 0.9516984310378388 1.0 1.0 3 O94826 1 +Regulation of post translational protein modification 0.3937428691035856 0.0602388351192618 0.9519654159069002 1.0 1.0 3 O75718 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3255697638946992 0.0600458113498138 0.9521191483079424 1.0 1.0 8 P55061,O60313,P18031,O76024 4 +Icosanoid catabolic process 0.4807333747669474 0.0579996718538956 0.9537488899110204 1.0 1.0 2 O95870 1 +Trna transcription 0.3306376360808635 0.0576962574516998 0.95399057485296 1.0 1.0 5 Q9Y5Q9,P62875,Q8WUA4,Q9Y5Q8 4 +Positive regulation of oxidative stress induced cell death 0.3303690219090514 0.0571511612941831 0.9544247821698488 1.0 1.0 5 P23246,Q13546 2 +Endocrine hormone secretion 0.4788688626476232 0.0571034627640204 0.954462778039696 1.0 1.0 2 Q06124 1 +Response to progesterone 0.3296180263335109 0.0556343369048735 0.9556331099604738 1.0 1.0 5 P30536 1 +Cellular response to sodium arsenite 0.4754505904288494 0.0555197203081638 0.9557244196454427 1.0 1.0 2 P09651 1 +Cellular response to salt 0.4754505904288494 0.0555197203081638 0.9557244196454427 1.0 1.0 2 P09651 1 +Regulation of extracellular matrix disassembly 0.3866956792042308 0.0547833822285271 0.9563110395796692 1.0 1.0 3 Q7Z460,O75122 2 +Positive regulation of extracellular matrix disassembly 0.3866956792042308 0.0547833822285271 0.9563110395796692 1.0 1.0 3 Q7Z460,O75122 2 +Negative regulation of protein targeting to mitochondrion 0.4723430702299659 0.0541449703840202 0.9568196635879738 1.0 1.0 2 O95429 1 +Mating behavior 0.3854522847373393 0.053870010915932 0.9570387297815072 1.0 1.0 3 P05067,P07686 2 +Reproductive behavior 0.3854522847373393 0.053870010915932 0.9570387297815072 1.0 1.0 3 P05067,P07686 2 +Vitamin catabolic process 0.4704785581106441 0.0533491156120827 0.9574537472917516 1.0 1.0 2 Q8IYS1 1 +Regulation of macroautophagy 0.3025557042226773 0.0532817253226556 0.957507440596444 1.0 1.0 55 P09601,P21281,O60858,O15118,P04062,P27544,Q9Y371,O15269,P12235,Q93050,Q9UHD9,P54646,P21796,Q9Y487 14 +Regulation of fc receptor mediated stimulatory signaling pathway 0.3373756218905382 0.0530995337817704 0.9576526029187626 1.0 1.0 4 P07948,Q9UKG1,Q08722 3 +Lateral ventricle development 0.469857054070868 0.0530885824348414 0.9576613285220794 1.0 1.0 2 Q9Y5K5 1 +Negative regulation of cellular senescence 0.4698570540708601 0.0530885824348384 0.957661328522082 1.0 1.0 2 P67809 1 +Genomic imprinting 0.4645742697327635 0.0509677112198446 0.9593512498074526 1.0 1.0 2 Q6PD62 1 +Regulation of genetic imprinting 0.4645742697327635 0.0509677112198446 0.9593512498074526 1.0 1.0 2 Q6PD62 1 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.3811004041032053 0.0507863767850017 0.9594957466189946 1.0 1.0 3 Q99729,P11940 2 +Anterograde neuronal dense core vesicle transport 0.4636420136731055 0.050610468098533 0.9596359211806064 1.0 1.0 2 P33176 1 +Dense core granule transport 0.4636420136731055 0.050610468098533 0.9596359211806064 1.0 1.0 2 P33176 1 +Regulation of viral transcription 0.3270431544233091 0.0505138676451331 0.9597128987301786 1.0 1.0 5 O60858 1 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.3804787068697586 0.0503600353063575 0.959835483158506 1.0 1.0 3 Q99873,Q86X55 2 +Embryonic brain development 0.3261862158549501 0.0488372526859004 0.961048994231284 1.0 1.0 5 P62995 1 +Cellular response to ketone 0.284922448306479 0.048361495345899 0.9614281456407971 1.0 1.0 19 Q9H4A6,P54646,O95831,P63096 4 +Skin development 0.3022856338200461 0.048159976793307 0.9615887470451534 1.0 1.0 36 O75844,Q13510,Q15392 3 +Post translational protein modification 0.3074972448675431 0.0475752246851114 0.9620547775021222 1.0 1.0 11 O60725,P46977 2 +Axon ensheathment in central nervous system 0.4546302050963502 0.0474077814175379 0.9621882273208636 1.0 1.0 2 Q92542 1 +Erythrocyte maturation 0.4546302050963501 0.0474077814175379 0.9621882273208636 1.0 1.0 2 P11413 1 +Positive regulation of notch signaling pathway 0.4543194530764605 0.0473051719382255 0.9622700060887316 1.0 1.0 2 P40763 1 +Metanephric nephron tubule epithelial cell differentiation 0.4543194530764566 0.0473051719382241 0.9622700060887328 1.0 1.0 2 P42224 1 +Golgi to vacuole transport 0.3243997300822033 0.0467220429911407 0.9627347617621558 1.0 1.0 6 Q99523 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3321464893845636 0.0462864377379727 0.9630819488413808 1.0 1.0 4 P61978 1 +Axoneme assembly 0.3739776314082325 0.0461086691797475 0.9632236363527676 1.0 1.0 3 Q15555 1 +Regulation of interleukin 1 mediated signaling pathway 0.3720857942182219 0.0449409457466757 0.9641543798119014 1.0 1.0 3 Q01804,Q86Y07 2 +Positive regulation of programmed necrotic cell death 0.3720857942182178 0.0449409457466735 0.9641543798119032 1.0 1.0 3 P04637,Q13546 2 +Intermediate filament bundle assembly 0.3714385226978115 0.0445484517667154 0.9644672313617316 1.0 1.0 3 P07196 1 +5s class rrna transcription by rna polymerase iii 0.3305348258706388 0.0442678008738435 0.9646909376830388 1.0 1.0 4 Q8WUA4,Q9Y5Q9,Q9Y5Q8 3 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.3683556108175371 0.0427275210254516 0.9659187409920575 1.0 1.0 3 O60341,P14174 2 +Suckling behavior 0.3680447622008115 0.0425483195944704 0.9660615931358398 1.0 1.0 3 P05067,Q92968 2 +Glutamate biosynthetic process 0.3680447622008113 0.0425483195944704 0.9660615931358398 1.0 1.0 3 O75746,P00367 2 +Positive regulation of lamellipodium organization 0.3003742981908956 0.0418326217613322 0.96663212936144 1.0 1.0 14 Q8WUW1,P63000,P60953,P61160,P61158,Q7L576,Q9Y6W5,P42345,Q9Y2A7,Q9BR76,Q16658,Q9ULV4,P50570 13 +Monoubiquitinated protein deubiquitination 0.3222967919472667 0.0417271305705805 0.9667162257242216 1.0 1.0 6 Q9Y6J9 1 +Mrna alternative polyadenylation 0.3283582089552158 0.0416016550077598 0.9668162538802798 1.0 1.0 4 Q8N684,Q16630,Q96MU7 3 +Smooth muscle cell apoptotic process 0.3222029521128338 0.0415063813095839 0.966892205690382 1.0 1.0 6 P98175,Q53EL6 2 +Negative regulation of macrophage chemotaxis 0.4322560596644014 0.0412126926328908 0.9671263350125628 1.0 1.0 2 P14174 1 +Negative regulation of macrophage migration 0.4322560596644014 0.0412126926328908 0.9671263350125628 1.0 1.0 2 P14174 1 +Regulation of collateral sprouting 0.4310130515848437 0.0409333761248582 0.967349009436713 1.0 1.0 2 Q8N0X7 1 +Protein k29 linked ubiquitination 0.364952835799329 0.0408090087235815 0.9674481574203112 1.0 1.0 3 Q15386 1 +Negative regulation of glycolytic process 0.426973275326303 0.0400676428164162 0.9680391983681296 1.0 1.0 2 P40763 1 +Stress induced premature senescence 0.4232442510876497 0.0393234056956757 0.968632545999248 1.0 1.0 2 Q16539 1 +Replicative senescence 0.4232442510876463 0.0393234056956749 0.9686325459992486 1.0 1.0 2 O96017 1 +Regulation of reactive oxygen species metabolic process 0.2982862192937777 0.0390794205231812 0.9688270684772404 1.0 1.0 33 P52789,P42785,Q8IXJ6,P51790,O75027,P30536,Q9BSK2,Q9H300,P00374 9 +Substrate dependent cell migration cell extension 0.3258781663585318 0.0386473566757458 0.9691715453069364 1.0 1.0 4 O00560 1 +Positive regulation of cell size 0.4142324425108948 0.0377267925969029 0.9699055137958776 1.0 1.0 2 O60341 1 +Intra golgi vesicle mediated transport 0.2828900225072771 0.0375449849852132 0.9700504725815484 1.0 1.0 19 O95249,Q8TBA6,Q96JB2 3 +Cdc42 protein signal transduction 0.4105034182722278 0.0371435480468013 0.970370549648046 1.0 1.0 2 A0MZ66 1 +Negative regulation of excitatory postsynaptic potential 0.4095711622125701 0.0370043652793245 0.9704815251363452 1.0 1.0 2 P38919 1 +Negative regulation of nervous system process 0.4095711622125685 0.0370043652793243 0.9704815251363454 1.0 1.0 2 P53634 1 +Negative regulation of myelination 0.4095711622125685 0.0370043652793243 0.9704815251363454 1.0 1.0 2 P53634 1 +Primary mirna processing 0.3201125289503722 0.0366030673653658 0.9708014977670016 1.0 1.0 7 P22626 1 +Negative regulation of establishment of protein localization to mitochondrion 0.3565433633820439 0.0364624580412574 0.970913612933904 1.0 1.0 3 O95817,O95429 2 +L serine transport 0.4033561218148109 0.0361406874525241 0.9711701796096426 1.0 1.0 2 Q9H9B4 1 +Regulation of transcription involved in g1 s transition of mitotic cell cycle 0.4014916096954822 0.0359023864633991 0.9713601929732154 1.0 1.0 2 O75312 1 +Diapedesis 0.3993163455562572 0.035635872885903 0.9715727040512304 1.0 1.0 2 P46108 1 +Positive regulation of leukocyte cell cell adhesion 0.2819788180855798 0.0353841687965042 0.9717734082774652 1.0 1.0 22 P00813,Q08722,P30825,P23396,Q9NUQ9,P04439 6 +Autophagy of peroxisome 0.3965195773772674 0.0353107706849146 0.9718319349231864 1.0 1.0 2 Q5T8D3 1 +Receptor clustering 0.300816194759449 0.034107879753414 0.9727911250078952 1.0 1.0 13 O43805,P49354,P57105,O15258 4 +Membrane depolarization during action potential 0.378185208203868 0.0336108652469023 0.9731874579505716 1.0 1.0 2 Q12955 1 +Response to iron ii ion 0.3688626476072273 0.0329872824158439 0.9736847292850952 1.0 1.0 2 P21399 1 +Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.3567433188315869 0.0323653955146878 0.974180658400966 1.0 1.0 2 Q07812 1 +Response to human chorionic gonadotropin 0.3558110627719181 0.0323251522495976 0.9742127510885104 1.0 1.0 2 P48507 1 +Peptidyl serine autophosphorylation 0.339341205717849 0.0317593960857323 0.9746639275182888 1.0 1.0 2 Q13546 1 +Regulation of spontaneous synaptic transmission 0.3459674682474185 0.0317434154498477 0.9746766717952308 1.0 1.0 3 P05067 1 +Spontaneous synaptic transmission 0.3459674682474185 0.0317434154498477 0.9746766717952308 1.0 1.0 3 P05067 1 +Regulation of bone remodeling 0.3371659415786354 0.0317024286611615 0.9747093580701648 1.0 1.0 2 P02786 1 +Regulation of bone resorption 0.3371659415786354 0.0317024286611615 0.9747093580701648 1.0 1.0 2 P02786 1 +Necroptotic signaling pathway 0.3365444375388557 0.0316868048289531 0.9747218178248772 1.0 1.0 2 Q13546 1 +Neutrophil activation involved in immune response 0.2980111870727283 0.0311282717969624 0.9751672429566998 1.0 1.0 2 P51809 1 +Neutrophil degranulation 0.2980111870727283 0.0311282717969624 0.9751672429566998 1.0 1.0 2 P51809 1 +Regulation of synaptic transmission dopaminergic 0.2970789310130641 0.0311217572985778 0.975172438257256 1.0 1.0 2 O75955 1 +Positive regulation of heterotypic cell cell adhesion 0.2970789310130641 0.0311217572985778 0.975172438257256 1.0 1.0 2 O75955 1 +Positive regulation of toll like receptor 3 signaling pathway 0.2970789310130641 0.0311217572985778 0.975172438257256 1.0 1.0 2 O75955 1 +Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.2743940335612316 0.0310169688255715 0.9752560070175598 1.0 1.0 2 Q9UNS2 1 +Antibacterial humoral response 0.2712865133623504 0.0310086221771604 0.9752626634776216 1.0 1.0 2 P04439 1 +Negative regulation of i kappab kinase nf kappab signaling 0.3178202357735596 0.0305566606369645 0.9756231057967466 1.0 1.0 7 Q86UT6,Q13546 2 +Positive regulation of exosomal secretion 0.3157851125610635 0.0298409160627635 0.9761939269854578 1.0 1.0 8 Q99816,O14964 2 +Positive regulation of intracellular protein transport 0.3029702205280678 0.0293972497190888 0.9765477662644336 1.0 1.0 48 Q7Z434,Q05D32,Q92544,P31751,Q15154,P27105,Q9Y282,Q9Y371,Q9Y6B6,Q9UHD1,O43464,O00410,P51572,O14737,P55786,P50402,Q9H270,Q9NR31,P06493 19 +Protein autoubiquitination 0.3014505504302539 0.0292211355513515 0.9766882246977528 1.0 1.0 12 Q96J02,Q9NX47,P19474,O60858 4 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.3366490519117249 0.02821534743508 0.9774903966145654 1.0 1.0 3 Q07812,O43464 2 +Regulation of type b pancreatic cell development 0.3335405657444864 0.0271594690090073 0.9783325428163256 1.0 1.0 3 P49840,P49841 2 +U4 snrna 3 end processing 0.316313997962961 0.0266477849912524 0.978740659864312 1.0 1.0 7 Q96B26 1 +Cellular response to leptin stimulus 0.3316827259851529 0.0265558039051167 0.9788140241898736 1.0 1.0 3 Q16739 1 +Response to leptin 0.3316827259851529 0.0265558039051167 0.9788140241898736 1.0 1.0 3 Q16739 1 +Toll like receptor 3 signaling pathway 0.3146095181805793 0.0263190915757081 0.9790028273099912 1.0 1.0 4 O75955,Q5KU26 2 +Positive regulation of neuron projection development 0.2886721566128276 0.025841545345085 0.9793837245089247 1.0 1.0 27 Q14108,Q9Y4G8,Q9UQB8 3 +Long chain fatty acid biosynthetic process 0.3270127447932915 0.0251255758668379 0.9799548000277144 1.0 1.0 3 Q96PU8,O00154 2 +Detoxification of nitrogen compound 0.3270127447932896 0.0251255758668373 0.9799548000277148 1.0 1.0 3 P21266,Q5VT66 2 +Response to caffeine 0.3270127447932896 0.0251255758668373 0.9799548000277148 1.0 1.0 3 Q92769,Q9NVV0 2 +Cellular response to exogenous dsrna 0.3139897205254857 0.0245449792057372 0.9804179062912428 1.0 1.0 8 Q9NUD5,O75955,Q7Z434 3 +Positive regulation of lamellipodium assembly 0.3001870324189584 0.0241279992616469 0.9807505096391904 1.0 1.0 12 Q8WUW1,P63000,P60953,P61160,P61158,Q7L576,Q9Y6W5,P42345,Q9Y2A7,Q16658,P50570 11 +Negative regulation of dna biosynthetic process 0.3065420560747766 0.0227369799819529 0.9818600776933022 1.0 1.0 10 Q99543,P04637,P07910,P27544,Q96TA1,P09651,Q9H0A0,Q01780,Q9NVN8 9 +Positive regulation of non motile cilium assembly 0.3110419906687329 0.0214680880431922 0.9828722596459004 1.0 1.0 5 Q9P2S5,Q16181,Q15555,P27695 4 +Response to topologically incorrect protein 0.2978106166316209 0.0202495834739478 0.9838442740884634 1.0 1.0 56 Q9Y4P3,P55061,Q9BUN8,Q13217,O14657,Q15363,Q92575,P46379,Q7Z2K6,Q13438,P57088,Q96HY6,Q9Y679,Q15629,O76024,P48723 16 +Megakaryocyte development 0.3052533416226339 0.0199250651777035 0.9841031499920392 1.0 1.0 3 Q06124,Q9Y6W5 2 +Regulation of response to interferon gamma 0.3052533416226327 0.0199250651777032 0.9841031499920394 1.0 1.0 3 Q16543,P08238 2 +Response to potassium ion 0.3039062320754329 0.0196729604320312 0.9843042610540612 1.0 1.0 3 Q14168 1 +Cellular response to potassium ion 0.3039062320754329 0.0196729604320312 0.9843042610540612 1.0 1.0 3 Q14168 1 +Chromatin remodeling at centromere 0.30721393034825 0.0191706850508026 0.9847049432445736 1.0 1.0 4 Q6IPU0,P49321,Q9NRZ9 3 +Lung cell differentiation 0.3094830524576548 0.0188921782067575 0.9849271193155792 1.0 1.0 5 P09960 1 +Positive regulation of cell adhesion molecule production 0.2971712775878195 0.0185178626025477 0.9852257277125108 1.0 1.0 3 O75955,Q5KU26 2 +Regulation of toll like receptor 3 signaling pathway 0.2971712775878188 0.0185178626025474 0.9852257277125108 1.0 1.0 3 O75955,Q14254 2 +Plasma membrane raft organization 0.2971712775878184 0.0185178626025474 0.9852257277125108 1.0 1.0 3 O75955,Q9UNF0 2 +Plasma membrane raft assembly 0.2971712775878184 0.0185178626025474 0.9852257277125108 1.0 1.0 3 O75955,Q9UNF0 2 +Sugar mediated signaling pathway 0.2965495803543708 0.018419691734527 0.9853040433746856 1.0 1.0 3 P17480,Q9NWS0 2 +Vesicle fusion to plasma membrane 0.2887783649362831 0.0173036603796631 0.9861943654806302 1.0 1.0 3 Q12846,O95721 2 +Regulation of reactive oxygen species biosynthetic process 0.2996091631690987 0.0165563750691758 0.9867905274347816 1.0 1.0 11 O75027,Q9BSK2,P51790 3 +Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest 0.2744793285669912 0.0157230639967958 0.987455326861925 1.0 1.0 3 P04637,O96017 2 +Nad metabolic process 0.2979659367804721 0.0152907906131807 0.9878001896519002 1.0 1.0 12 P52789 1 +Negative regulation of anoikis 0.2673298103823496 0.0151248493503134 0.987932576313458 1.0 1.0 3 Q07820,Q9Y3E5 2 +Negative regulation of lipoprotein particle clearance 0.2660864159154546 0.0150320465705178 0.9880066138015848 1.0 1.0 3 Q92945,P41240 2 +Negative regulation of autophagy 0.2836245250030365 0.0149510782776161 0.988071209893093 1.0 1.0 25 Q8IXJ6,P10619,O15118 3 +Regulation of platelet activation 0.2505439850792708 0.0141097592807195 0.988742414451154 1.0 1.0 3 P07948,Q9BWH2 2 +Glycerol ether metabolic process 0.3074010177713022 0.012523905364913 0.9900076304832672 1.0 1.0 9 Q99757,O15228,Q6IAN0 3 +Interferon gamma mediated signaling pathway 0.3054432348366961 0.0124243362097391 0.9900870689941768 1.0 1.0 5 P04637,Q16543,P42224,P08238 4 +Positive regulation of tor signaling 0.3096991991326678 0.0122043791629825 0.9902625560192404 1.0 1.0 8 Q9H4A6 1 +Regulation of plasma lipoprotein particle levels 0.2908589322768565 0.0109492159328897 0.9912639642083544 1.0 1.0 15 P09601,Q92945,P35610,Q8WTV0,Q6P1A2,P38571 6 +Regulation of toll like receptor 4 signaling pathway 0.2972636815920343 0.0106680421518239 0.9914882953221424 1.0 1.0 4 P07948,Q9UKG1,O75955 3 +Toll like receptor 4 signaling pathway 0.2972636815920343 0.0106680421518239 0.9914882953221424 1.0 1.0 4 P07948,Q9UKG1,O75955 3 +Positive regulation of cell cell adhesion mediated by cadherin 0.2972636815920345 0.0106680421518239 0.9914882953221424 1.0 1.0 4 Q07157,P55196,O75955 3 +Regulation of heterotypic cell cell adhesion 0.2972636815920319 0.0106680421518219 0.991488295322144 1.0 1.0 4 O75955,Q14254,Q9H4A3 3 +Calcium ion export 0.2967574923235431 0.0102683532240575 0.991807183471744 1.0 1.0 4 P20020 1 +Carbohydrate mediated signaling 0.2966417910447702 0.0101774304389637 0.9918797255674744 1.0 1.0 4 P17480,Q5KU26,Q9NWS0 3 +Cysteine metabolic process 0.3020256202102853 0.0071846514533991 0.994267526848254 1.0 1.0 5 P48507,P25325 2 +Positive regulation of histone acetylation 0.3064225053270846 0.0070003888744785 0.994414543417105 1.0 1.0 6 Q9NWS0 1 +Negative regulation of telomere maintenance via telomerase 0.3061605476042326 0.0064715861819622 0.9948364573442888 1.0 1.0 6 P07910,P09651,Q9H0A0,Q01780,Q9NVN8 5 +Negative regulation of bmp signaling pathway 0.2913557213930264 0.0061935946791216 0.9950582580243884 1.0 1.0 4 Q8N0X7,Q8NC56,Q05D32 3 +Snorna localization 0.2910447761193975 0.0059694680877517 0.9952370818640012 1.0 1.0 4 P22087,Q8WWY3,Q9NWS0 3 +Mitochondrial genome maintenance 0.2965422137602103 0.0049839480150405 0.9960234012899069 1.0 1.0 11 P12235 1 +Histamine production involved in inflammatory response 0.2888681592039748 0.004431699286847 0.9964640271353008 1.0 1.0 4 Q9UNH7,P07948,P51809 3 +Histamine transport 0.2888681592039748 0.004431699286847 0.9964640271353008 1.0 1.0 4 Q9UNH7,P07948,P51809 3 +Histamine secretion 0.2888681592039748 0.004431699286847 0.9964640271353008 1.0 1.0 4 Q9UNH7,P07948,P51809 3 +Centriole assembly 0.3073302262013286 0.0043991239283116 0.9964900182575768 1.0 1.0 7 P41208 1 +Fibroblast growth factor receptor signaling pathway 0.3072001995328673 0.0040905786192314 0.9967361995770724 1.0 1.0 7 Q9Y639 1 +Dna damage response signal transduction resulting in transcription 0.284376620027497 0.0014271850966467 0.9988612714325488 1.0 1.0 4 Q9UNS2 1 +Regulation of cell cell adhesion mediated by cadherin 0.2973561430793091 0.0003655996214123 0.999708293713138 1.0 1.0 5 Q07157,P55196,O75955,P49593 4 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..01e47313dac42c78a382d6b99aed9e1db81a44f7 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular valve development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell chemotaxis", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bud elongation involved in lung branching", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac muscle tissue regeneration", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in kidney development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated inhibitory signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response inhibiting cell surface receptor signaling pathway", "Immune response inhibiting signal transduction", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion import across plasma membrane", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral mesoderm development", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid catabolic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell proliferation", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 mediated signaling pathway", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor 2 signaling pathway", "Negative regulation of toll like receptor 4 signaling pathway", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Notochord development", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation cycle", "Ovulation cycle process", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of digestive system process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell population maintenance", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked deubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein lipoylation", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intestinal lipid absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of iron ion transmembrane transport", "Regulation of iron ion transport", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Tolerance induction to self antigen", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRAT1", "BRD2", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C17orf75", "C18orf32", "C19orf70", "C1QBP", "C2CD5", "C3orf58", "C5orf51", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPP", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG3", "COG4", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "LYSMD3", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL55", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS18A", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VANGL2", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VKORC1L1", "VMA21", "VPS11", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "WAPL", "WARS", "WASF2", "WASHC2A", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YIF1B", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YOD1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF148", "ZNF207", "ZNF281", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["AASDHPPT", "ABCB1", "ABCB7", "ABCD1", "ABHD10", "ABHD16A", "ACAD11", "ACADVL", "ACAT2", "ACBD3", "ACBD5", "ACO1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTR2", "ACTR3", "ADA", "ADI1", "ADPGK", "AFDN", "AGK", "AGPAT5", "AGTRAP", "AIFM1", "AKAP1", "AKAP8", "AKAP8L", "AKR1B1", "AKT1S1", "AKT2", "ALDH1B1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALG1", "ALG12", "ALKBH5", "AMOT", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO10", "ANO6", "AP2M1", "APEX1", "APOL2", "APOO", "APOOL", "APP", "APPL1", "ARHGAP17", "ARL6IP1", "ARL6IP5", "ARV1", "ASAH1", "ASPH", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATPIF1", "AUP1", "B4GAT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCL2L13", "BRAT1", "BRK1", "BSG", "BUD23", "C18orf32", "C19orf70", "C1QBP", "C3orf58", "C5orf51", "CANX", "CARM1", "CBL", "CCDC22", "CCDC47", "CCDC51", "CCNB2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDS2", "CENPP", "CERS1", "CERS2", "CETN2", "CHEK2", "CHERP", "CHKA", "CHMP5", "CHORDC1", "CHST12", "CHST14", "CIRBP", "CISD1", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC4", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLUH", "CNNM3", "COA3", "COG3", "COLEC12", "COLGALT1", "COMT", "COPS3", "COPS5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7A2L", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRTAP", "CSK", "CSNK1A1", "CSNK2B", "CTDSPL2", "CTR9", "CTSA", "CTSC", "CYB5B", "CYFIP1", "CYP51A1", "DAGLB", "DCTN1", "DCTPP1", "DDA1", "DDHD2", "DDRGK1", "DDT", "DDX5", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS7B", "DHX9", "DIABLO", "DLD", "DLGAP5", "DNAJA3", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DOHH", "DOLPP1", "DUSP12", "DYM", "DYNC2H1", "EBP", "ECE1", "EIF2S1", "EIF3E", "EIF3H", "EIF4A3", "EMC7", "EMD", "EPB41L5", "ERAP1", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "ESPL1", "ESYT1", "ESYT2", "ETFDH", "ETNK1", "EXO1", "EXOSC10", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC8", "FADS2", "FAM129B", "FAM162A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FARSB", "FBL", "FGFR1OP", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FLOT1", "FLOT2", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FUCA1", "FUCA2", "FUNDC2", "FUS", "G6PD", "GAA", "GALNT1", "GALNT4", "GAMT", "GBA", "GCLM", "GGCX", "GHITM", "GIGYF2", "GINS1", "GINS2", "GLA", "GLB1", "GLG1", "GLUD1", "GM2A", "GMPS", "GNAI1", "GNL3L", "GNPAT", "GOLGA2", "GOLGA5", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPAA1", "GPR108", "GPR89B", "GSK3A", "GSK3B", "GSTM3", "GSTO1", "GTF3C2", "GTF3C3", 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sha256:6e25e5cbf2aa241492c34380204b949f320d3f041f9f91ec2fb49676d12fe391 +size 146854 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e744f5f610ed6054937065da4b8af4ae2b8a573 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:692d64359267adcd0648a0f7d62baf693e70c37db84876380a56973b0bed13cf +size 117493 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f06cfd5d93037bf965e0dd18828bc528f8ec65e6 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,41 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Intrinsic component of organelle membrane 98 155 4.538697141320176 5.660286263031722e-06 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 4.006854451429354e-20 0.0006121599419964 7.080113180934568e-06 5.902661852372762e-15 5.1909150525609335e-27 +Inner mitochondrial membrane protein complex 40 85 4.5003077804781215 6.785514093055056e-06 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 4.38549417133505e-10 3.265745079131887e-06 5.467249505514427e-06 4.347633275019364e-11 1.3570800243961308e-10 +Outer membrane 51 95 3.798883214555541 0.0001453495574805 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 2.5440119697839788e-06 0.0002393341141964 1.0544094136922732e-05 1.6742515423577266e-06 4.409987442568302e-08 +Lysosomal lumen 17 32 3.484169725350157 0.0004936663255601 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 1.3391805146980802e-10 0.0437266531990119 0.0005246070390923 6.546781738469502e-08 2.197044118262804e-09 +Intrinsic component of mitochondrial inner membrane 28 38 3.4730647603781875 0.0005145511816397 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 1.5719071227554384e-10 0.0248568883498602 0.0001225586688041 1.604003607050196e-09 7.041463148156409e-12 +Golgi membrane 60 144 3.4577444411685976 0.0005447178332858 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 2.31980556847384e-07 0.0001908684614395 0.0008895026951456 3.895043154169477e-06 2.266429225753764e-07 +Intrinsic component of mitochondrial membrane 34 55 3.2586238659403057 0.0011195399157297 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 1.4502202742069942e-09 0.0571768496395965 0.0010419295639301 4.825978027817743e-09 1.167148790015892e-11 +Intrinsic component of endoplasmic reticulum membrane 36 61 3.1748898234443907 0.0014989340297417 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 2.521486703042773e-07 0.0003613299844351 0.0014611582954646 0.0002272816947708 4.3830319923569645e-11 +Outer mitochondrial membrane protein complex 14 17 2.7788368527241487 0.0054553917164281 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0002717646605189 0.0937235599037543 0.0161297090986061 9.045491853019026e-05 0.0002747300414667 +Intrinsic component of golgi membrane 12 14 2.763180510381915 0.0057241100312599 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0086257880709111 0.1868885334554594 0.339526513295544 0.0180565405233996 0.0001478156049624 +Nuclear outer membrane endoplasmic reticulum membrane network 162 344 2.6466303714620305 0.0081298161031428 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 1.863066469832368e-21 1.863080629732415e-06 7.486652793287747e-07 1.889554927946156e-16 3.993353893667844e-32 +Endoplasmic reticulum golgi intermediate compartment membrane 18 30 2.643528748595517 0.0082046797839383 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 3.7619332166891866e-05 0.0024333620388206 0.0166167011229059 0.0020006005653745 5.412109352262341e-05 +Golgi cisterna 17 28 2.6397522226425805 0.0082966660954708 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.0003551558384187 0.3024216363859021 0.1605058634275269 0.0003558175935407 0.0001840815286022 +Golgi cisterna membrane 13 21 2.5533282383497897 0.0106698890400023 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0047982913038071 0.2260688267312995 0.0921147949975289 0.0081044088621321 0.0007920809146458 +Intrinsic component of plasma membrane 43 79 2.539500386421378 0.0111010922687602 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.6734886420081322 0.674583845081253 0.486114653744096 0.6961322988647874 0.3343360929921224 +Organelle inner membrane 117 260 2.5106276540317385 0.0120516739791318 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 6.910951607970935e-21 8.059186689692238e-06 9.356962046203126e-09 7.155256134256937e-19 5.30628574662529e-29 +Cis golgi network 6 17 2.499705304477604 0.0124296654813116 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.0001524432549311 0.1747599807978781 0.0005505691972034 3.475150315812665e-05 0.0004730993907641 +Vacuolar lumen 19 61 2.4874306164527367 0.0128669549405642 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 6.453665761161135e-08 0.1090224971962506 0.0053807722164466 2.033133062369488e-05 5.687860207994201e-07 +Transport vesicle 34 95 2.4636778230764445 0.0137519661137379 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 0.0290244223149916 0.3675531568855632 0.1133593840721368 0.0515596375225491 0.0158726478369225 +Proteasome core complex beta subunit complex 5 7 2.4220238524198625 0.0154343374348433 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0020591533048899 0.0432957136582515 0.0849171013653387 0.0186627473263165 2.8311070051942505e-05 +Organelle membrane contact site 12 17 2.383111517167728 0.0171669930242512 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.0899509529230909 1.0 1.0 0.051542815486873 0.0257423149537502 +Mib complex 8 11 2.3229220330548435 0.0201833412611442 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.0064033235801391 1.0 1.0 0.0033170374819039 0.0225979674873623 +Tim23 mitochondrial import inner membrane translocase complex 3 7 2.3172382257229613 0.0204907582929365 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.000236451798507 0.0526645480715484 0.0001426699384292 9.549361773523036e-05 9.569573614901708e-05 +Cytochrome complex 5 17 2.300755295249449 0.0214054666392551 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0016621291292449 0.1330370821365251 0.2489059409173845 0.0005802452812718 0.0023211498250519 +Respirasome 21 49 2.259203590015156 0.0238707236225417 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 9.385030576384704e-06 0.0082661149627475 0.0507760863542232 5.692764928188808e-06 2.631621948630412e-06 +Pore complex 4 9 2.1579205262180805 0.0309340113119251 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0014751616716224 0.0802348466038066 0.0117676307173903 0.0073447144383531 0.0010053263520343 +Haus complex 2 5 2.141818977281996 0.0322080517176517 1.7142857142857142 4.192118226600985 0.9491182117305148 0.3338762298151981 1.141316695812668 1.4443833619809177 1.0587020246145291 0.3035334299176759 0.0229934988929211 1.0 1.0 0.0147480216610697 0.0053031795330487 +Intrinsic component of peroxisomal membrane 6 9 2.139136103583488 0.0324246471931408 1.9320388349514563 4.434466019417476 0.5069121698582412 0.444591863161664 1.4960279832433574 1.753796563107492 1.0627811042818465 0.325067944975853 0.0097377531702328 1.0 0.1375212864755611 0.0050923434600555 0.0334620993119388 +Proton transporting two sector atpase complex proton transporting domain 7 11 2.138385658359094 0.0324854554960811 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 0.0097377531702328 0.0023758658868836 0.009201700056446 0.0495157384890535 4.367834065541858e-05 +Azurophil granule membrane 9 24 2.1362109282649726 0.0326622250968988 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0125959111054095 1.0 0.0746250944081647 0.3051232152156647 5.575737006440399e-05 +Microbody membrane 15 35 2.1301794981726068 0.033156796999294 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0016399549581251 0.2449590299452383 0.1075014480598519 0.0004129808075874 0.0015622461376846 +Organelle subcompartment 185 417 2.0988816627325355 0.0358273337042465 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 2.191989465798957e-22 9.183644430231483e-06 1.5176467703937815e-06 2.9005870711524402e-18 7.768856095096451e-31 +Endoplasmic reticulum tubular network 9 15 2.075052812681541 0.0379816403665709 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 0.0281770440971773 1.0 1.0 0.097689242801984 0.0034992238505004 +Golgi associated vesicle membrane 4 20 2.060320265269814 0.0393679338293204 4.201456310679611 19.589805825242717 0.79417597045559 0.3511132904952779 2.457541951272857 2.384047500904294 1.2111660039755976 0.3110721945776767 0.0070098432849392 0.0163255968864409 0.0069536692626337 0.0025916473916576 0.0119603409362114 +Copi coated vesicle membrane 4 14 2.043287358159946 0.0410240002978554 2.9611650485436893 12.451456310679612 0.9351146201256926 0.2894293018559171 1.7580457491925867 1.2208038158644114 1.2401568068418547 0.2855671555488221 0.0011555838382646 0.0027067874988798 0.0004672463302539 0.0004788146962384 0.0007388687073799 +Respiratory chain complex iii 2 7 2.039788302591826 0.0413714153845727 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.0064033235801391 0.0619434524836269 0.1203280145079081 0.0033170374819039 0.0225979674873623 +Mitochondria associated endoplasmic reticulum membrane 6 10 2.0364429984058257 0.0417058914492716 4.191747572815534 9.240291262135925 0.7019541594808174 0.4009163152547425 2.0831338076447135 1.0418560326821893 1.1194321867771957 0.3336055532093068 0.427681256978171 1.0 1.0 0.3559534457378639 0.0539281835546241 +Mitochondrial protein containing complex 57 164 1.982085287314116 0.0474696959310767 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 3.639012546278977e-09 3.398663014149417e-06 1.1317171027364182e-06 8.432767835636034e-11 3.324863983777743e-11 +Proton transporting two sector atpase complex 11 24 1.9722220559467567 0.0485842628974966 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 0.0191572938808404 0.0005966319628977 0.004393919895815 0.0479498850625808 0.0001729005795719 +Endoplasmic reticulum golgi intermediate compartment 22 54 1.964996806876136 0.0494146071202192 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0001876141329787 0.0013172485850158 0.0155897140308576 0.0024873657620056 0.0008689936972513 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8bf431ffbcc882940a3341492434616657cfd42e --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 897, + "title": "Average number of proteins per term", + "value": 29.190635451505017 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1acd1d5c2f9c2d3eeed00745525066fd6cbc7619 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4189ddb08c777dffbad690352a0c12d438193ec --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,240 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Intrinsic component of organelle membrane 0.6589524292046847 4.538697141320176 5.660286263031722e-06 0.0050644234915396 0.0030433030707356 155 P56589,Q15125,Q5SNT2,Q9P0S2,Q9HC21,P57088,Q15629,O60830,Q8N4V1,Q9Y282,O75844,O14975,O75431,Q5HYI7,Q14739,Q96ER9,P51572,Q6UXV4,Q96HA9,Q86YN1,Q99595,Q9HCU5,Q6P4A7,Q15070,O14925,Q9H3K2,Q9BUN8,O15258,P33897,Q5XKP0,Q969X5,Q5BJH7,Q9Y287,P42892,Q86XL3,O15118,Q9Y2R0,Q8TB61,Q9NVH1,Q13505,P13473,P50416,O95470,O60499,O00767,Q9H4I9,Q00325,O75192,P17152,Q9BWH2,Q6Y1H2,Q16891,Q9H9P8,P20020,O43808,P57105,Q92643,O43292,Q9BUR5,Q9Y5Y5,P12235,O43505,Q16134,Q03518,Q9NPA0,Q96A33,Q9Y679,O43752,Q8N8Q8,Q5T9L3,Q9NQC3,Q9NZ01,Q9NRB3,O76024,Q8NBI6,L0R6Q1,Q9Y6N1,Q9UH99,Q9H490,Q9UG56,P98194,Q96AQ8,Q9P035,Q9BUB7,Q9Y4P3,Q9Y5Z9,O96008,O75298,Q16799,P27824,Q9UBM7,Q96NB2,Q99442,Q8N2H4,Q9Y512,O95070,Q15041,P10321 98 +Inner mitochondrial membrane protein complex 0.5999193402584554 4.5003077804781215 6.785514093055056e-06 0.0060681408038743 0.0030433030707356 85 O43676,P03886,Q9NVH1,Q13505,Q8IYU8,O14949,P00846,O60830,P62072,Q96CU9,Q9Y5J6,O75306,Q9H4I9,O95139,Q86Y39,Q9Y584,O75964,O75431,Q5HYI7,P14406,Q99643,P24539,Q6UXV4,Q9UDW1,Q99595,P13073,O14548,Q9NX14,Q9Y6M9,Q9BUR5,P56385,O14925,O75251,P12236,Q96IX5,Q5XKP0,P22695,Q9Y512,P21912,O75947 40 +Outer membrane 0.5440434682954479 3.798883214555541 0.0001453495574805 0.122245229659124 0.0434595176866932 95 Q96H55,O00264,Q96HS1,Q99536,Q7Z434,Q9NVH1,Q13505,Q5VT66,Q9NZ45,O43169,Q9NUQ2,P50416,Q8IWA4,P30536,Q6NUM9,P21796,Q8WY22,Q9NX47,Q9Y277,Q9Y6C9,Q07820,Q9NS69,Q9UKU0,Q9Y371,Q9BWH2,O60313,O96008,Q16891,O75431,Q5HYI7,P45880,Q8N4H5,Q99720,Q9NQZ5,P09601,P57105,O00165,Q13057,Q6UXV4,Q9UBM7,Q9BUR5,Q86UT6,P50402,P52789,Q9NZJ7,Q15388,O94826,Q5XKP0,Q9Y512,Q9BVC6,Q8N2A8 51 +Lysosomal lumen 0.7632501141855081 3.484169725350157 0.0004936663255601 0.3578465803039522 0.0814353160762274 32 P07602,Q8IV08,Q14108,P38435,Q9NZJ7,Q8NHP8,P04062,P04066,P54802,P10619,P11117,Q9UMR5,O14773,Q13510,P50897,P06865,P06280 17 +Intrinsic component of mitochondrial inner membrane 0.7465027836700134 3.4730647603781875 0.0005145511816397 0.3697704726678034 0.0814353160762274 38 Q96AQ8,Q9Y2R0,Q9NVH1,Q13505,Q9HC21,Q9P0S2,O60830,Q9H4I9,Q00325,P17152,Q8N8Q8,O75431,Q5HYI7,Q9H9P8,Q96ER9,Q6UXV4,Q99595,Q9Y6N1,Q15070,Q6P4A7,Q9BUR5,O14925,Q96NB2,Q9H3K2,Q5XKP0,Q9Y512,Q16134,Q9UG56 28 +Golgi membrane 0.5525674158502736 3.4577444411685976 0.0005447178332858 0.3866042909072126 0.0814353160762274 144 Q9Y287,Q9H8Y8,P98194,P10321,Q6RW13,Q8TB61,Q8NF37,Q15363,Q9H3P7,O15260,O14653,Q10472,Q9BXS4,O95197,P24390,Q15392,O60499,Q8N4A0,Q8N4V1,O43752,Q9Y282,Q9Y5Z9,Q8NBN3,O00400,Q8NCH0,Q5T9L3,Q16739,Q9Y371,Q7LGA3,O95249,O43731,Q9NRB3,Q8IZA0,Q9H4A6,Q9UHD1,Q9Y3B3,P35613,Q10713,Q9HC07,P51572,P49755,L0R6Q1,Q9P2W9,Q16799,O00461,Q8TBA6,Q9BUR5,Q14108,Q96JB2,Q9H7Z7,Q9Y3E0,Q8N2H4,O15258,P61026,P11166,O43505,O95070,Q5BJH7,Q8IV08,P51790 60 +Intrinsic component of mitochondrial membrane 0.654512318334969 3.2586238659403057 0.0011195399157297 0.6338784367113169 0.1434610434870867 55 Q96AQ8,Q9Y2R0,Q9NVH1,Q13505,Q9HC21,Q9P0S2,P50416,Q9BUB7,O60830,Q9H4I9,Q00325,P17152,Q8N8Q8,Q9BWH2,O96008,O75431,Q5HYI7,Q9H9P8,P57105,Q96ER9,Q6UXV4,Q99595,Q9Y6N1,Q15070,Q6P4A7,Q9BUR5,O14925,Q96NB2,Q9H3K2,P12235,Q5XKP0,Q9Y512,Q16134,Q9UG56 34 +Intrinsic component of endoplasmic reticulum membrane 0.6158706242914178 3.1748898234443907 0.0014989340297417 0.7396042068284879 0.1680679780847963 61 Q15125,Q86XL3,Q03518,Q8TB61,Q9P035,Q9NPA0,Q96A33,O95470,P57088,Q9Y679,Q15629,Q9Y4P3,Q8N4V1,O00767,Q9Y282,O75844,O14975,Q6Y1H2,Q9NQC3,Q9NZ01,O76024,O75298,P51572,Q8NBI6,Q86YN1,Q16799,P27824,Q9HCU5,O43292,Q9UBM7,Q9BUN8,Q99442,Q969X5,Q15041,Q9H490,P10321 36 +Outer mitochondrial membrane protein complex 0.7151296239621391 2.7788368527241487 0.0054553917164281 0.9926044961934324 0.5134526698040169 17 Q6UXV4,Q9NVH1,Q15388,Q9NS69,O96008,Q13505,O94826,Q16891,Q5XKP0,Q9Y512,Q5HYI7,O75431,Q9BUR5,Q8N4H5 14 +Intrinsic component of golgi membrane 0.7563664230191169 2.763180510381915 0.0057241100312599 0.9941964084256476 0.5134526698040169 14 P98194,Q9Y282,Q9Y5Z9,Q8TB61,Q8N2H4,O15258,L0R6Q1,Q9NRB3,O43505,Q969X5,O95070,Q5BJH7 12 +Nuclear outer membrane endoplasmic reticulum membrane network 0.5775392984902233 2.6466303714620305 0.0081298161031428 0.9993393258541822 0.5217832790941542 344 Q15125,Q9H8Y8,Q969V3,Q6RW13,Q8N0U8,P30519,P27544,Q92575,P57088,P43307,O95197,Q15629,Q96AG4,P24390,Q15392,Q8N4V1,Q9Y282,O75844,O00400,Q8N511,O14975,O00560,Q9UKU0,Q9Y320,O43731,Q9BQE5,Q12797,Q14739,Q15800,Q99720,P09601,P35613,P51572,O95864,P61009,Q86YN1,P49755,Q13438,Q9P2W9,Q9HD20,Q9HCU5,O60725,Q14108,Q9BUN8,Q06136,Q5BJF2,P61026,Q7Z2K6,P67812,P33897,Q969X5,Q5BJH7,Q9BVC6,Q8IV08,O95772,P55061,Q86XL3,Q16850,Q4ZIN3,Q8TB61,Q15363,P49458,Q9NUQ2,O95470,Q9UGP8,Q9NZ08,Q96G23,O75340,O00767,Q5JRA6,Q53GQ0,O43909,Q8N5M9,Q9BRR6,Q9NTJ5,Q9H6H4,Q9NP80,Q6Y1H2,Q6NUK4,P51648,Q9BV10,Q9Y6B6,Q96N66,Q9UBV2,Q9NVV0,Q15904,Q96RQ1,Q5VV42,Q96PC5,O43292,Q9BUR5,Q9Y5Y5,P38435,Q9H3N1,A1L0T0,Q9H2C2,Q8NHH9,Q86UE4,Q9BU23,O00264,Q86SQ9,P48449,O60858,Q03518,Q8NF37,Q9NPA0,O95674,Q96A33,O15260,Q10472,Q9Y679,P62942,Q5T9L3,Q9NQC3,Q9NZ01,O76024,Q9Y3B3,Q9BVG9,Q96JJ7,Q8NBI6,P16615,P16435,Q15005,O43852,Q99523,Q96KC8,Q9Y5M8,Q9H490,Q07065,Q9BRK0,Q9P035,P35610,O14653,Q6NUM9,Q6P1A2,O43264,Q9BT22,Q9Y4P3,Q9NX47,Q9Y5Z9,O15269,O14735,Q9C0D9,Q9Y2B2,O75298,Q14534,Q9UBU6,Q70UQ0,Q16799,O75845,P27824,P51571,Q9UBM7,Q6NUQ4,P50402,Q99442,P46977,Q96HY6,O95070,Q15041,O75915,P10321 162 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6406675506309695 2.643528748595517 0.0082046797839383 0.9993825765730338 0.5217832790941542 30 Q9Y3B3,Q9Y282,Q15904,Q03518,Q96RQ1,Q8N511,P51572,Q9BVK6,Q15363,Q5BJH7,P49755,O15260,O14653,Q10472,Q969X5,O95070,P24390,Q12907 18 +Golgi cisterna 0.642070107309579 2.6397522226425805 0.0082966660954708 0.9994318662345376 0.5217832790941542 28 Q10713,Q12893,P98194,Q96JB2,Q8NBN3,P51572,Q15363,Q9Y3A3,O95249,Q99523,Q10472,Q9BXS4,Q9Y6B6,Q9H4A6,O00461,Q8TBA6,P0CG08 17 +Golgi cisterna membrane 0.6324155762817923 2.5533282383497897 0.0106698890400023 0.999933766009446 0.5217832790941542 21 Q10713,Q12893,P98194,Q96JB2,Q8NBN3,P51572,Q15363,Q9Y3A3,Q99523,Q10472,Q9Y6B6,Q9H4A6,O00461 13 +Intrinsic component of plasma membrane 0.4527965281375477 2.539500386421378 0.0111010922687602 0.9999552027052112 0.5217832790941542 79 Q9NR28,P55061,P05067,Q99797,O15118,Q9BRK0,P51790,Q9Y4G8,O60637,P10586,P05141,P20645,P27105,Q08722,Q00325,P17152,O00400,O00560,P05023,P11279,Q13641,Q9H1Z9,Q8WTV0,P20020,O43657,P35613,Q99805,P30825,Q9H2J7,P51572,Q9Y639,O95864,P16615,P27824,Q92542,P53985,Q12907,Q9UIQ6,O96005,P12235,P11166,P10321,O00264 43 +Organelle inner membrane 0.5393016778251715 2.5106276540317385 0.0120516739791318 0.9999810938090816 0.5217832790941542 260 O43676,P03886,Q5SNT2,Q9H061,Q70HW3,Q9P0S2,Q9HC21,Q8IYU8,O14949,P00846,O60830,P62995,O95139,O75844,Q9Y6C9,Q9Y584,O75964,O75431,Q5HYI7,O95831,Q14739,Q99720,Q96ER9,Q9H2V7,Q6UXV4,Q9BYC9,O75027,Q99595,O14548,Q9NX14,Q9HD33,Q6P4A7,Q15070,Q9H300,Q7Z7F7,O14925,O75251,Q9H3K2,Q9UBX3,Q9H2D1,Q6NUK1,Q5XKP0,Q9H1E5,P21912,O75947,Q9H2W6,Q9Y2R0,Q9NVH1,Q9Y619,Q13505,P62072,Q96CU9,P05141,O95167,Q13423,Q9H4I9,P82933,P17152,Q00325,P23786,Q8N442,Q86Y39,Q567V2,P23396,Q16891,Q9H9P8,P14406,Q10713,Q9BQT8,Q9UDW1,Q9Y241,P13073,P16260,Q9BUR5,Q8NI60,P12235,P22695,Q16134,O95674,P53701,O75306,Q8WUK0,Q9UDX5,O75208,Q8N8Q8,Q9NPL8,Q99643,Q7KZN9,Q9BYD1,Q9Y5J9,Q9Y6M9,Q9Y6N1,Q9BSK2,Q8IXM6,Q8NBN7,Q9UH99,Q9UG56,Q96AQ8,Q9NVI7,Q9BUB7,Q9Y5J6,Q6DKK2,O96008,P49748,Q9P015,P24539,O43772,Q9NVS2,Q9UJZ1,P56385,P50402,P12236,Q96NB2,Q9BRJ2,Q96IX5,Q9Y512,Q5T9A4 117 +Cis golgi network 0.6687627608267116 2.499705304477604 0.0124296654813116 0.9999865869338868 0.5217832790941542 17 Q9NPR9,O95249,O43731,O00461,P24390,Q8TBA6 6 +Vacuolar lumen 0.5391925246537854 2.4874306164527367 0.0128669549405642 0.9999909844052736 0.5217832790941542 61 Q8NHP8,P04062,P10619,P11117,P06865,P50897,P06280,Q9BTY2,P04066,Q9UMR5,Q13510,P07602,O14773,Q14108,P38435,Q9H7Z7,Q9NZJ7,P54802,Q8IV08 19 +Transport vesicle 0.4322183930404223 2.4636778230764445 0.0137519661137379 0.9999959674761512 0.5217832790941542 95 P05067,Q15363,O15260,O43760,Q96A57,O14653,Q15907,P24390,P20645,O60499,O75340,P50897,O43752,Q9UI14,P11279,O95249,O43731,Q9GZM5,Q9Y6B6,Q9UHD1,O76024,P20020,Q9Y3B3,P49755,O00461,Q92542,Q8TBA6,P04439,Q9BT78,Q9NR31,P61026,Q99523,P10321,P51790 34 +Proteasome core complex beta subunit complex 0.8422843905158065 2.4220238524198625 0.0154343374348433 0.9999991280676804 0.5217832790941542 7 P49721,P28070,P20618,P28074,P28072 5 +Organelle membrane contact site 0.6498437353840483 2.383111517167728 0.0171669930242512 0.9999998203940724 0.5217832790941542 17 Q96N66,O95772,Q96S66,Q96TC7,P51572,Q9NTJ5,A0FGR8,Q15388,O96008,Q9Y320,Q5XKP0,P27824 12 +Mib complex 0.7121664195936975 2.3229220330548435 0.0201833412611442 0.9999999886000576 0.5217832790941542 11 Q6UXV4,Q9NVH1,Q13505,Q5XKP0,Q9Y512,Q5HYI7,O75431,Q9BUR5 8 +Tim23 mitochondrial import inner membrane translocase complex 0.8190199216792928 2.3172382257229613 0.0204907582929365 0.9999999913968296 0.5217832790941542 7 O60830,O14925,Q99595 3 +Cytochrome complex 0.6366340960616761 2.300755295249449 0.0214054666392551 0.9999999962786676 0.5217832790941542 17 Q9UDW1,P13073,P22695,O14949,P14406 5 +Respirasome 0.5541515311430665 2.2592035900151557 0.0238707236225417 0.9999999996126688 0.5217832790941542 49 O43676,P03886,O14949,Q96CU9,O75306,Q13423,O95139,Q6DKK2,Q86Y39,P14406,Q99643,Q7KZN9,Q9UDW1,Q9Y241,P13073,O14548,Q9NX14,Q9Y6M9,O75251,P22695,P21912 21 +Pore complex 0.732985180218554 2.1579205262180805 0.0309340113119251 0.999999999999426 0.5217832790941542 9 Q9Y277,P21796,P45880,P12235 4 +Haus complex 0.8437275027632449 2.141818977281996 0.0322080517176517 0.9999999999998236 0.5217832790941542 5 O94927,Q9H6D7 2 +Intrinsic component of peroxisomal membrane 0.7292501551763775 2.1391361035834877 0.0324246471931408 0.9999999999998556 0.5217832790941542 9 P56589,Q9Y5Y5,O75192,O14975,Q96HA9,P33897 6 +Proton transporting two sector atpase complex proton transporting domain 0.6783236718475641 2.138385658359094 0.0324854554960811 0.9999999999998636 0.5217832790941542 11 P24539,Q93050,O75964,P00846,O75947,P56385,Q9Y487 7 +Azurophil granule membrane 0.5717929170897367 2.1362109282649726 0.0326622250968988 0.9999999999998842 0.5217832790941542 24 Q07065,P07602,Q9NZJ7,P42785,Q8NF37,P10253,O15260,Q9NQX7,P27105 9 +Microbody membrane 0.5646165456614186 2.1301794981726068 0.033156796999294 0.9999999999999268 0.5217832790941542 35 P56589,Q9Y5Y5,O75192,Q7Z434,O14975,Q15067,P50542,Q9UKU0,Q9NP80,Q96HA9,P51648,Q9NR77,P33897,O75381,O15228 15 +Organelle subcompartment 0.548148778391933 2.0988816627325355 0.0358273337042465 0.999999999999994 0.5332425201433137 417 Q4J6C6,Q15125,Q9H8Y8,Q969V3,Q6RW13,Q00765,Q8N0U8,P30519,P27544,Q92575,P57088,P43307,O95197,Q15629,Q96AG4,P24390,Q15392,Q9NX62,Q8N4V1,Q9Y282,Q8NBN3,O75844,O00400,Q8N511,O14975,O00560,Q9UKU0,Q9Y320,O43731,Q9BQE5,Q12797,Q14739,Q15800,Q99720,P09601,P35613,Q9NPR9,P51572,O95864,P61009,Q86YN1,P49755,Q13438,Q9P2W9,O00461,Q9HD20,Q9HCU5,O60725,Q14108,Q9BUN8,Q06136,Q5BJF2,P61026,Q7Z2K6,P67812,P33897,Q969X5,Q5BJH7,Q9BVC6,Q8IV08,O95772,P55061,P05067,Q86XL3,Q16850,Q4ZIN3,Q8TB61,P04062,Q15363,P49458,Q9NUQ2,Q96A57,O95470,Q9BXS4,Q9UGP8,Q9NZ08,Q96G23,P20645,O60499,O75340,O00767,Q5JRA6,Q53GQ0,Q12893,O43909,Q8N5M9,Q9BRR6,Q9NTJ5,Q9H6H4,Q9NP80,O95249,Q6Y1H2,P51648,Q6NUK4,Q9BV10,Q9Y6B6,Q9Y3A3,Q96N66,Q9UBV2,Q10713,Q9NVV0,Q9HC07,Q15904,Q96RQ1,Q5VV42,Q96PC5,O43292,Q8TBA6,Q9BUR5,Q9Y5Y5,Q96JB2,P38435,Q9H3N1,A1L0T0,Q9H2C2,Q8NHH9,Q86UE4,Q9BU23,O00264,Q86SQ9,P48449,O60858,Q03518,Q8NF37,Q9NPA0,O95674,Q96A33,O15260,Q10472,Q9Y679,P62942,O43752,Q5T9L3,Q9NQC3,Q9NZ01,Q9H4A6,O76024,Q9Y3B3,Q9BVG9,Q96JJ7,Q8NBI6,P16615,P16435,Q15005,O43852,Q99523,Q96KC8,Q9Y5M8,Q9H490,Q07065,P98194,Q9BRK0,Q9P035,P35610,O14653,Q6NUM9,Q6P1A2,O43264,Q9BT22,Q9Y4P3,Q9NX47,Q9Y5Z9,O15269,O14735,Q9C0D9,Q9Y2B2,O75298,Q14534,Q9UBU6,Q70UQ0,Q16799,O75845,P27824,P51571,Q9UBM7,Q6NUQ4,P50402,Q99442,Q8N2H4,P46977,Q96HY6,O95070,Q15041,O75915,P10321 185 +Endoplasmic reticulum tubular network 0.6247470328252707 2.0750528126815415 0.0379816403665709 0.9999999999999992 0.5407862128383194 15 P50402,Q9BRK0,Q00765,Q9H6H4,Q8NHH9,Q9H2C2,P61026,Q9NQC3,Q12797 9 +Golgi associated vesicle membrane 0.5601726320762583 2.060320265269814 0.0393679338293204 0.9999999999999998 0.5472210195905765 20 Q9Y287,Q8N511,P24390,O43731 4 +Copi coated vesicle membrane 0.6306048883115208 2.043287358159946 0.0410240002978554 1.0 0.5472210195905765 14 Q8N511,P24390,O43731,Q15363 4 +Respiratory chain complex iii 0.7587672417032404 2.039788302591826 0.0413714153845727 1.0 0.5472210195905765 7 Q9UDW1,O14949 2 +Mitochondria associated endoplasmic reticulum membrane 0.6849045182529236 2.0364429984058257 0.0417058914492716 1.0 0.5472210195905765 10 Q96N66,P51572,Q15388,Q9Y320,O96008,P27824 6 +Mitochondrial protein containing complex 0.4460334756481037 1.982085287314116 0.0474696959310767 1.0 0.5472210195905765 164 O43676,P03886,Q9NVH1,Q13505,Q8IYU8,O14949,P00846,O60830,P62072,P21796,Q96CU9,P05141,Q9Y5J6,O75306,Q9H4I9,P82933,O95139,Q86Y39,Q9NS69,Q567V2,Q9Y584,O75964,O96008,Q9P015,O75431,Q5HYI7,P14406,Q8N4H5,Q99643,P24539,Q6UXV4,Q9UDW1,Q9BYC9,Q9BYD1,Q9NVS2,Q99595,P13073,O14548,Q9NX14,Q9HD33,Q9Y5J9,Q9Y6M9,Q9BUR5,P56385,Q7Z7F7,O14925,O75251,P12236,Q9BRJ2,P12235,Q96IX5,Q5XKP0,P22695,Q9Y512,P21912,O75947,Q9H2W6 57 +Proton transporting two sector atpase complex 0.5489248238536413 1.9722220559467571 0.0485842628974966 1.0 0.5472210195905765 24 Q15904,P21281,P24539,Q8N511,O75964,Q93050,Q96IX5,P00846,O75947,P56385,Q9Y487 11 +Endoplasmic reticulum golgi intermediate compartment 0.5066697513500349 1.9649968068761356 0.0494146071202192 1.0 0.5472210195905765 54 Q02818,Q03518,Q15363,P80303,O15260,O14653,Q10472,P24390,Q9Y282,Q8N511,Q9UHD1,Q9Y3B3,Q15904,Q96RQ1,P51572,P49755,Q12907,Q9BVK6,O15258,Q969X5,O95070,Q5BJH7 22 +Copi coated vesicle 0.6027079653016886 1.939680975470822 0.0524184730394374 1.0 0.5564982785128071 15 Q8N511,P24390,O43731,Q15363 4 +Integral component of synaptic vesicle membrane 0.7851926101948279 1.8909125396305568 0.0586360202420968 1.0 0.5831887459004472 5 O43752,O60499 2 +Er ubiquitin ligase complex 0.7816485225505299 1.8755161692547764 0.0607217471638303 1.0 0.5831887459004472 5 Q9BUN8,Q13438,Q9UBU6,Q9Y679 4 +Coated vesicle 0.3829416552137989 1.8716474984539648 0.061255387472874 1.0 0.5831887459004472 90 P42892,P05067,Q9Y3A6,Q5VW38,Q15363,O14653,P24390,P20645,O75340,O43752,Q9Y282,Q8N511,P11717,O43731,Q9Y6B6,P51809,O94830,Q9Y3B3,O00165,Q96RQ1,P51572,P49755,Q12907,P04439,Q14108,Q9H270,Q9BVK6,Q9NR31,Q99523,Q969X5,O95070,Q5BJH7,P10321 33 +Nuclear inner membrane 0.5333185624138871 1.8660873792734685 0.0620291414225211 1.0 0.5831887459004472 21 Q9H1E5,P50402,Q8IXM6,O75844,Q5SNT2,Q9UH99,Q14739,Q99720 8 +Copii coated er to golgi transport vesicle 0.5292553093238478 1.8570846500259204 0.0632991117163899 1.0 0.5831887459004472 35 Q9Y3B3,P05067,Q9Y282,Q969X5,Q9BVK6,Q96RQ1,Q9NR31,Q15363,P49755,P04439,O14653,Q9Y6B6,O95070,Q5BJH7,Q12907,P10321,O75340 17 +Tim22 mitochondrial import inner membrane insertion complex 0.8433797367990846 1.852180578369036 0.063999896701965 1.0 0.5831887459004472 4 Q9Y584,P62072 2 +Photoreceptor inner segment 0.767217802515517 1.812594394851505 0.0698944029618631 1.0 0.5831887459004472 5 P11166,Q15555,P05023 3 +Endoplasmic reticulum 0.52610234843734 1.7880982539739791 0.0737601572728967 1.0 0.5831887459004472 517 P56589,Q15125,Q9H8Y8,Q969V3,Q6RW13,O75718,Q00765,Q8N0U8,P30519,P27544,O60506,P80303,Q92575,P10619,P43307,P57088,O95197,Q15629,Q96AG4,P24390,Q15392,Q8N4V1,Q9Y282,O75844,O00400,Q8N511,O14975,O00560,Q9UKU0,Q9Y320,O43731,Q9BQE5,Q12797,Q14739,Q9UHD1,Q13510,Q9UMX5,Q15800,Q99720,P09601,Q9NWM8,P13674,P35613,P51572,O15173,O95864,P61009,Q86YN1,O75503,P49755,Q13438,Q9P2W9,Q9HD20,Q9HCU5,Q8TCD1,Q6Y7W6,O60725,Q14108,Q9BUN8,Q06136,Q5BJF2,Q9UQB8,O15258,P61026,Q7Z2K6,P67812,P33897,Q969X5,Q5BJH7,Q9BVC6,Q9NUQ7,Q8IV08,O95772,P55061,Q02818,Q86XL3,Q16850,P05067,O15118,Q96LJ7,Q4ZIN3,Q8TB61,Q13217,P04062,Q15363,P49458,Q9NUQ2,Q96A57,O95470,Q9UGP8,Q9UHB9,Q9NZ08,Q96G23,O00584,O75340,O00767,Q5JRA6,Q53GQ0,O43909,Q8N5M9,Q9BRR6,Q9Y680,Q9NTJ5,Q9H6H4,Q9NP80,P23396,Q6Y1H2,P84157,P51648,Q6NUK4,Q9BV10,Q9Y6B6,O95433,Q96N66,Q9UBV2,Q9NVV0,Q15904,Q14257,Q96RQ1,Q5VV42,Q96PC5,O43292,Q9BUR5,Q9Y5Y5,P38435,P52789,Q9H3N1,A1L0T0,Q9H2C2,Q8NHH9,Q86UE4,Q9BU23,O00264,Q86SQ9,P48449,O60858,Q03518,Q8NF37,Q9NPA0,O95674,Q96A33,O15260,Q10472,Q9Y679,P62942,Q9BTY2,Q5T9L3,Q13641,Q9NQC3,Q9NZ01,O76024,P48723,Q9Y3B3,Q9BVG9,Q96JJ7,O00165,Q8NBI6,P16615,P16435,Q15005,Q9Y3E0,O43852,Q99523,Q96KC8,Q9Y5M8,Q9H490,Q99797,Q07065,P98194,Q9BRK0,Q9P035,P35610,P30536,O14653,Q01105,Q6NUM9,Q6P1A2,O43264,P27105,Q9BT22,Q9Y4P3,Q9NX47,Q9Y5Z9,Q92791,P05023,O15269,O14735,Q9C0D9,Q9Y2B2,O75298,Q14534,Q9UBU6,Q70UQ0,Q16799,O75845,P27824,P51571,Q9UBM7,Q6NUQ4,P50402,Q9NR31,Q99442,P46977,O43390,Q96HY6,O95070,Q15041,O75915,P10321 209 +Sarcoplasmic reticulum membrane 0.6387310895759997 1.7873869556637825 0.0738749684440891 1.0 0.5831887459004472 10 O75298,Q12797,P16615,P62942,Q9BVC6 5 +Extrinsic component of mitochondrial inner membrane 0.8252523850692568 1.7785406954353755 0.0753150943540559 1.0 0.5831887459004472 4 Q8NI60 1 +Proteasome core complex 0.5853815471526197 1.7693835658533037 0.0768298862894365 1.0 0.5831887459004472 14 P49721,P28070,P20618,P28074,P28072,Q99436 6 +Vacuolar membrane 0.4034181083621298 1.7681613067226405 0.0770339407631015 1.0 0.5831887459004472 126 O95772,P42892,Q07065,P21281,O15118,Q8NF37,P04062,O15260,P10619,Q9BXS4,P11117,Q8NCG7,Q9NQX7,P27105,P51798,Q15012,Q8N511,P11279,Q93050,Q8WTV0,Q9Y487,P07602,Q9HC07,Q9H2V7,P42785,O75503,Q9UIQ6,Q14108,Q9NZJ7,P10253,Q99523,Q8IV08,Q9NZZ3 33 +Respiratory chain complex iv 0.6326632349631351 1.754175385840191 0.0794004594741466 1.0 0.5831887459004472 10 P09669,P13073,P22695,O14548,P20674,P14406 6 +Lipid droplet 0.5164366095822768 1.7503425119395275 0.0800592294143889 1.0 0.5831887459004472 34 P48449,Q07065,Q8NF37,O43760,Q01105,P09455,Q9Y679,Q8NBX0,Q8TCD1,Q99720 10 +Mitochondrial envelope 0.5094579733355799 1.7452110136331564 0.0809481448060682 1.0 0.5831887459004472 343 O43676,Q96H55,Q99536,P03886,Q9H061,Q70HW3,Q9P0S2,Q9HC21,Q9NZ45,O43169,Q8IYU8,O14949,P00846,O60830,P21796,Q8WY22,O95139,Q9Y6C9,Q9NS69,Q9UKU0,Q9Y371,Q9Y584,O75964,Q9Y320,O75431,O95831,Q5HYI7,P45880,Q8N4H5,O15228,Q9NQZ5,P09601,Q96ER9,Q9H2V7,Q96H78,Q6UXV4,O75027,Q9BYC9,Q99595,O14548,Q9NX14,Q9HD33,Q15070,Q6P4A7,Q9H300,Q7Z7F7,O14925,O75251,Q9H3K2,Q9UBX3,Q9H2D1,Q96A26,Q6NUK1,Q5XKP0,P33897,P21912,O75947,Q9BXK5,Q8N2A8,Q9H2W6,P55061,Q7Z434,Q9Y2R0,Q9NVH1,Q9Y619,Q13505,Q9NUQ2,P50416,P62072,Q96CU9,P05141,O95167,O00584,Q13423,Q9H4I9,P82933,Q00325,P17152,P23786,Q8N442,Q86Y39,Q9BWH2,Q9NP80,Q567V2,P23396,Q9H9P8,P14406,P57105,Q10713,Q9BQT8,Q9UDW1,Q9Y241,P13073,P16260,Q9BUR5,Q8NI60,P52789,P12235,P22695,Q16134,O00264,O95674,P53701,O75306,Q8WUK0,Q9UDX5,O75208,Q8N8Q8,Q9Y277,Q9NPL8,Q9H4A6,Q99643,O00165,Q7KZN9,Q9BYD1,Q9Y5J9,Q9Y6M9,Q9Y6N1,Q9BSK2,Q86UT6,Q9NZJ7,Q8NBN7,Q9UG56,Q9NR28,Q96AQ8,P30536,Q9NVI7,Q9BUB7,Q9Y5J6,Q9NX47,Q9Y5Z9,Q6DKK2,O96008,P49748,Q9P015,P24539,O43772,Q9NVS2,Q9UJZ1,P56385,P12236,Q96NB2,Q9BRJ2,Q96IX5,Q9Y512,Q5T9A4 146 +Micos complex 0.7506489784245364 1.739904978181473 0.0818757044215825 1.0 0.5831887459004472 5 Q6UXV4,Q5XKP0,Q9BUR5 3 +Golgi stack 0.5115403141062755 1.739655717374899 0.0819194893906982 1.0 0.5831887459004472 38 Q10713,Q96JB2,Q8NBN3,Q15363,O95249,Q99523,Q10472,Q9BXS4,Q9H4A6,O00461,Q8TBA6 11 +Ciliary transition zone 0.7129893371470046 1.7154250547331205 0.0862673250868426 1.0 0.5894391920171986 6 Q15154,A6NIH7,P41208 3 +Proton transporting atp synthase complex 0.593405041232026 1.70690479671773 0.0878397491245557 1.0 0.5894391920171986 12 P24539,O75964,Q96IX5,P00846,P56385 5 +Proton transporting atp synthase complex coupling factor f o 0.6865059196531118 1.6957586030748515 0.0899316051873238 1.0 0.5894391920171986 7 O75964,P56385,P00846,P24539 4 +Synaptic vesicle membrane 0.5719697022371508 1.6866675532478652 0.0916672944591456 1.0 0.594278320212032 14 O43752,O43760,O76024,O60499 4 +Golgi medial cisterna 0.7341113240305022 1.6669008142076438 0.0955341289797444 1.0 0.599259536327488 5 Q9BXS4 1 +Postsynaptic density membrane 0.6942017141023353 1.6280245036277126 0.1035196901403563 1.0 0.6070564333179896 6 P57105,Q99720 2 +Platelet alpha granule lumen 0.569929287821124 1.6184064547120125 0.1055750318813895 1.0 0.6070564333179896 13 Q6UXV4,Q8NBX0,Q8NBM8,Q9NUQ9,Q9NTK5 5 +Uniplex complex 0.7849911195894184 1.6134959425119109 0.1066368040636938 1.0 0.6075443306042924 4 Q9H4I9 1 +Rough endoplasmic reticulum membrane 0.5674542024028049 1.6033364137962625 0.1088604012221987 1.0 0.6075443306042924 13 Q5BJF2,P49458,Q96A33,P51571,Q15041,Q9Y5M8 6 +Platelet alpha granule 0.5289383223873132 1.6001469443054122 0.1095659888610334 1.0 0.6075443306042924 17 Q96JJ7,Q6UXV4,Q8NBX0,Q8NBM8,Q9NUQ9,Q9NTK5 6 +Exocytic vesicle 0.4892099593559514 1.5842544709528503 0.1131358220842997 1.0 0.6075443306042924 41 O43752,P05067,Q9BT78,Q9UI14,P51790,P20020,P11279,P61026,O43760,Q96A57,Q92542,Q15907,O76024,O60499,P50897 15 +Chloride channel complex 0.684429841444836 1.5823169731470563 0.1135772279016031 1.0 0.6075443306042924 6 P51798,Q9C0H2 2 +Snare complex 0.4935744053612234 1.581395801128657 0.1137875669359209 1.0 0.6075443306042924 20 O95249,O43752,Q9P2W9,O60499 4 +Intrinsic component of synaptic vesicle membrane 0.610810598418362 1.5232472377313038 0.1276968619746905 1.0 0.6470329328416626 9 O43752,O60499 2 +Mitotic spindle microtubule 0.6291149714047013 1.5199214380324668 0.1285307217390412 1.0 0.6470329328416626 8 O94927,Q9H6D7 2 +Mcm complex 0.6694200735605436 1.511801943827527 0.1305842547743065 1.0 0.6470329328416626 6 Q14566,P25205,P49736 3 +Mitochondrial permeability transition pore complex 0.6981790506918113 1.5068765345721482 0.1318423072091206 1.0 0.6470329328416626 5 P21796 1 +Emc complex 0.6259499147565883 1.5036646157238984 0.1326677444615223 1.0 0.6470329328416626 8 Q8N4V1 1 +Nucleotide activated protein kinase complex 0.7565805742613404 1.4959796564779582 0.1346589566155789 1.0 0.6470329328416626 4 P10644 1 +Specific granule membrane 0.5132675775024096 1.4940974819422466 0.1351501420499741 1.0 0.6470329328416626 17 Q07065,Q08722,O14975,P30519,P27105,O00264 6 +Protein lipid complex 0.7555132658363264 1.491550922883721 0.1358169121225767 1.0 0.6470329328416626 4 Q9UHG3,Q9BUR5 2 +Sarcoplasm 0.4746951935487656 1.441730361769662 0.1493784548904762 1.0 0.6935818790287698 20 O75298,O00165,P52789,O43852,Q12797,P16615,P62942,Q9BVC6 8 +Mitochondrial intermembrane space protein transporter complex 0.873484612993471 1.4357782915314543 0.1510654388898209 1.0 0.6935818790287698 3 Q9Y5J9,P62072 2 +Intrinsic component of nuclear inner membrane 0.6306357041832118 1.4222680034321975 0.1549484638213556 1.0 0.6994244792756962 7 Q14739,Q9UH99 2 +Vacuolar proton transporting v type atpase v0 domain 0.7360786826087075 1.410764766299765 0.1583139867321552 1.0 0.6994244792756962 4 Q93050,Q9Y487 2 +Proton transporting v type atpase v0 domain 0.7360786826087075 1.410764766299765 0.1583139867321552 1.0 0.6994244792756962 4 Q93050,Q9Y487 2 +Secretory granule membrane 0.3911053198061253 1.4015971461116177 0.1610355797037521 1.0 0.6994244792756962 72 Q07065,Q4KMQ2,Q8NF37,Q15363,P30519,O15260,Q9NQX7,P27105,Q08722,O14975,P11279,Q93050,Q969Q5,P35613,P07602,Q96JJ7,P42785,P49755,Q9NZJ7,P10253,P61026,Q5T9A4,P10321,O00264 24 +Nadh dehydrogenase complex 0.4713281663755411 1.3865776347628458 0.1655705920304195 1.0 0.7050633287640908 27 O75306,O43676,O75251,O95139,P03886,Q86Y39,Q9NX14,Q9Y6M9,Q96CU9 9 +Dynactin complex 0.6706704586407723 1.3832853314085365 0.1665773939421146 1.0 0.7050633287640908 5 P61163,Q9UJW0,O75935 3 +Endoplasmic reticulum protein containing complex 0.410269289289882 1.3750150038141322 0.1691267932002143 1.0 0.7122381854487897 66 Q03518,Q9NPA0,P49458,Q9UGP8,Q9Y679,P62942,O43264,Q8N4V1,Q53GQ0,O15269,P13674,Q9UBV2,Q92643,Q9UBU6,P61009,Q13438,P51571,O43292,Q15005,Q9BUN8,P46977,P67812,Q15041,Q9Y5M8,Q9H490 25 +Nuclear pore outer ring 0.6000468288372693 1.3699170383060255 0.1707128003875473 1.0 0.7132353487821292 8 Q9BW27,Q8NFH4,Q12769 3 +Proton transporting v type atpase complex 0.5298376153103883 1.3257687163007068 0.1849163182191497 1.0 0.7438113786662661 12 Q93050,Q8N511,Q9Y487 3 +Transporter complex 0.4191005688198599 1.279860406747346 0.200594234524581 1.0 0.7702800378633348 60 O75306,O43676,Q9H4I9,P51798,P03886,Q9Y6M9,O75381,Q9Y5J6,Q86Y39,Q9UDW1,Q9Y696,Q9C0H2,P22695,O14949,Q9Y5J9,P62072,P62942,Q96CU9 18 +Oxidoreductase complex 0.4156922804746021 1.2725107580185988 0.2031917041807813 1.0 0.7702800378633348 61 O75306,O43676,P03886,Q86Y39,Q9UDW1,O43169,P22695,O14949,Q96CU9,Q99643 10 +Cortical endoplasmic reticulum 0.8246813801678565 1.2526614200065906 0.2103289519917264 1.0 0.7732174997400761 3 Q9H2C2,P50402 2 +Signal peptidase complex 0.8172210133664786 1.2247158975505146 0.220682282179863 1.0 0.7775321315201544 3 Q15005,P67812 2 +Rough endoplasmic reticulum 0.4497416591431457 1.215280670550984 0.2242590615929522 1.0 0.7775321315201544 34 P05067,Q07065,Q99442,Q5BJF2,P49458,Q96A33,Q9UQB8,Q5VV42,P27824,P51571,Q15041,Q9Y5M8 12 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6333476695602364 1.2146363504158242 0.2245048183542028 1.0 0.7775321315201544 5 O75964,P56385,P24539 3 +Intrinsic component of mitochondrial outer membrane 0.5027481048858583 1.2031308293473213 0.2289256968824977 1.0 0.7791845173237459 13 P57105,Q15388,Q9BWH2,O96008,O94826,P50416,Q8IWA4,Q9GZY8,Q9UH62 9 +Golgi apparatus subcompartment 0.3385858960420661 1.17884929517365 0.2384581911688654 1.0 0.7951561244552874 97 O43752,Q10713,Q9H4A6,Q9NPR9,Q9HC07,Q8NBN3,Q96JB2,Q5T9L3,P04062,Q15363,O95249,Q99523,Q96A57,Q10472,Q9BXS4,O00461,Q8TBA6,O60499 18 +Blood microparticle 0.4731838519578094 1.1609938286315182 0.2456444091683081 1.0 0.7972942506903253 16 Q08380,P38435,P04062,P11166,P27105 5 +Golgi lumen 0.6203319673291758 1.155713701415736 0.2477982819449962 1.0 0.7972942506903253 5 O00461,Q9NX62 2 +Triglyceride rich plasma lipoprotein particle 0.9313238036047186 1.1514223945377826 0.2495585051122097 1.0 0.7972942506903253 2 Q9UHG3 1 +Platelet dense granule 0.7970158532794385 1.149195228248533 0.2504754880517734 1.0 0.7972942506903253 3 Q08380,Q92520 2 +Postsynaptic specialization membrane 0.5220171766073698 1.1323237075395716 0.2574983665369388 1.0 0.7972942506903253 10 P57105,Q99720 2 +Hrd1p ubiquitin ligase erad l complex 0.7918745559486129 1.1300290668463906 0.258463976752042 1.0 0.7972942506903253 3 Q9BUN8 1 +Endoplasmic reticulum tubular network membrane 0.6674346569532346 1.1244837329025443 0.2608078676888898 1.0 0.7972942506903253 4 Q8NHH9 1 +Pole plasm 0.6656412517007018 1.1170169928988147 0.2639870595931177 1.0 0.7972942506903253 4 Q9Y2W6 1 +Lumenal side of membrane 0.5491994783165246 1.104719568473071 0.2692811215004949 1.0 0.799899229007357 8 P51572,P10619,P27824,P10321,P04439 5 +Golgi associated vesicle 0.4352879995717438 1.0963508695306372 0.2729252557097468 1.0 0.799899229007357 31 Q9Y287,Q9Y3B3,Q8N511,Q15363,O43731,P24390 6 +Vacuole 0.4119099222166615 1.0919848603790188 0.2748397557249378 1.0 0.799899229007357 218 O95772,P42892,Q07065,P21281,O15118,Q8NF37,Q8NHP8,P04062,O15260,Q96A57,P10619,Q9BXS4,Q9Y679,P11117,Q8NCG7,Q9NQX7,O14964,P27105,P06865,P50897,P51798,P06280,P00813,Q9BTY2,Q15012,Q8N511,Q8NCC3,P04066,P11279,Q93050,Q8WTV0,Q9NX40,Q9UMR5,Q969Q5,Q15165,Q13510,Q9Y487,P07602,Q9HC07,Q9H2V7,P42785,O75503,O14773,Q9UIQ6,Q14108,P38435,Q9NZJ7,Q9H7Z7,Q9UHG3,Q5BJF2,P10253,P54802,Q99523,Q96S38,Q9NZZ3,Q8IV08 56 +Compact myelin 0.7814806594776433 1.0913617339503054 0.2751137433085615 1.0 0.799899229007357 3 Q9NR77 1 +Sec61 translocon complex 0.6592278135015239 1.0903345558276505 0.2755657985793096 1.0 0.799899229007357 4 P51571 1 +Translocon complex 0.6592278135015239 1.0903345558276505 0.2755657985793096 1.0 0.799899229007357 4 P51571 1 +Dendrite membrane 0.7755672987255224 1.069417323531801 0.2848816647297298 1.0 0.799899229007357 3 Q14168,P20020 2 +Azurophil granule 0.3759990966669848 1.064436213491261 0.2871311359864479 1.0 0.799899229007357 68 Q07065,Q99536,Q8NF37,Q13217,P13473,O15260,P10619,P17900,Q9NQX7,P27105,P06865,P06280,Q9BTY2,O00560,P11279,P04066,P07602,P42785,Q9H7Z7,Q9NZJ7,P16278,P10253 22 +Nuclear outer membrane 0.5076166319375303 1.049908056559148 0.2937603871023051 1.0 0.8082363065362362 10 P50402,Q9UBM7,Q6NUM9,Q99720 4 +Endoplasmic reticulum quality control compartment 0.5703311939712595 1.0402625735958118 0.2982179271985046 1.0 0.8082363065362362 6 Q9BUN8,O60858 2 +Mitochondrial crista 0.6451323993028482 1.0318269909303233 0.3021531726650757 1.0 0.8082363065362362 4 O60313,Q9BUB7 2 +Neurofilament 0.7643767485234655 1.0280155454151274 0.3039425152695045 1.0 0.8082363065362362 3 P07196,P07197 2 +Platelet dense granule lumen 0.890926041019267 1.004160600451652 0.3153012094968823 1.0 0.8152135633879644 2 Q92520 1 +Synaptonemal structure 0.5859405570993171 1.0003014163930002 0.3171646619604074 1.0 0.8152135633879644 5 Q7Z5K2 1 +Perinuclear endoplasmic reticulum 0.580804505443135 0.9771797151475504 0.3284801885769162 1.0 0.8204812124370913 5 O60858 1 +Apical plasma membrane 0.4153554065117522 0.9590955625547656 0.3375106056717047 1.0 0.8211868398648513 42 Q99797,P21281,O00165,P30825,P05023,Q9Y4G8,Q86UE4,P08183,P11166,Q9Y6M7,P53985,Q9ULK5 12 +Microbody 0.376583186755014 0.9430990826318436 0.3456302249380671 1.0 0.8284253212250834 64 P56589,Q7Z434,P50542,O75192,O14975,Q9UKU0,Q9NP80,Q2T9J0,P51648,P08670,Q709F0,O15228,Q15067,Q96HA9,O15254,Q9Y5Y5,Q96CN7,Q8N4Q0,Q9NR77,O14734,P33897,O75381 22 +Er to golgi transport vesicle membrane 0.4083250061250682 0.924874778154982 0.3550310475887941 1.0 0.8284253212250834 22 Q9Y3B3,Q9NR31,Q15363,P49755,O14653,Q9Y6B6,P10321,O75340 8 +Phagocytic vesicle membrane 0.4089608001747515 0.9090497921193392 0.3633238433370847 1.0 0.8285059917492889 25 Q03518,P11279,P13473,Q93050,P04439,P61026,Q15907,P10321,Q9Y487 9 +Paraspeckles 0.5427520429942729 0.9090026169623584 0.3633487444312764 1.0 0.8285059917492889 6 Q8WXF1,Q16630,P23246,Q15233 4 +Derlin 1 retrotranslocation complex 0.6064797703158722 0.8729268705352576 0.3827029390800476 1.0 0.8372793569629334 4 Q9BUN8,Q9UBV2 2 +Inhibitory synapse 0.8415164698570559 0.8290866682633918 0.4070553670460226 1.0 0.8663963560971295 2 Q9Y639 1 +Endoplasmic reticulum exit site 0.4044669901960491 0.7931000966659332 0.427719506528188 1.0 0.8663963560971295 18 Q5JRA6,Q9NR31,P04439,Q9HCU5,Q9Y6B6,Q96PC5,O75340 7 +Intrinsic component of presynaptic membrane 0.5354281497731717 0.775116981778516 0.4382705378674445 1.0 0.8663963560971295 5 Q9Y639,P20020,P27824 3 +Cis golgi network membrane 0.6936866774331517 0.7723776431617433 0.4398907913061012 1.0 0.8663963560971295 3 Q9NPR9 1 +Dendritic shaft 0.5332237611507097 0.7654443369603663 0.4440070001575549 1.0 0.8663963560971295 5 P05067,Q9UQB8 2 +Zymogen granule membrane 0.8166563082659847 0.744023443176127 0.4568622925684975 1.0 0.8663963560971295 2 Q15363 1 +Endocytic vesicle membrane 0.3890585250281385 0.7258596040245865 0.4679248429212292 1.0 0.8739751441007602 41 Q14108,Q03518,Q5T9L3,P11279,P13473,P11717,Q93050,P04439,P61026,Q8WTV0,Q15907,P20645,P10321,Q9Y487 14 +Dna replication preinitiation complex 0.4270565739296308 0.6971181466690711 0.485728858553863 1.0 0.8817717452806257 12 P25205,P49736,Q9Y248,O75419 4 +Secondary lysosome 0.7967681789931663 0.6778642529468616 0.4978577670888873 1.0 0.8931568341575594 2 P11279 1 +Autolysosome 0.7967681789931663 0.6778642529468616 0.4978577670888873 1.0 0.8931568341575594 2 P11279 1 +Intrinsic component of vacuolar membrane 0.7967681789931411 0.6778642529467775 0.4978577670889406 1.0 0.8931568341575594 2 O15118 1 +Nuclear pore nuclear basket 0.4656390277996356 0.6710902915760028 0.5021630112914943 1.0 0.8990822777015378 8 Q8NFH5 1 +Zymogen granule 0.6631992555151832 0.6669786302137231 0.5047857835558895 1.0 0.899279361052599 3 Q15363 1 +Envelope 0.4549241181253561 0.6589249666645849 0.5099439525799896 1.0 0.899279361052599 513 O43676,Q96H55,Q15125,Q99536,P03886,Q9H061,Q5SNT2,Q70HW3,Q92575,Q9P0S2,P80303,Q9NZ45,O43169,Q9HC21,P57088,O14949,Q8IYU8,P00846,O60830,Q96AG4,P21796,Q15154,Q8WY22,P62995,O95139,O75844,O00560,Q9Y6C9,Q9NS69,Q9UKU0,Q9Y371,Q9Y584,O75964,Q9Y320,O75431,O95831,Q5HYI7,Q14739,P45880,Q8N4H5,Q99720,Q9NQZ5,O15228,P09601,Q96ER9,Q9H2V7,Q96H78,Q6UXV4,O15173,Q9UBU9,O75027,Q9BYC9,Q99595,O14548,Q9NX14,Q9HD33,Q15070,Q6P4A7,Q9H300,Q8N1F7,Q7Z7F7,O14925,O75251,Q9H3K2,Q9UBX3,P42167,Q9H2D1,Q5BJF2,Q96A26,Q6NUK1,P42166,Q5XKP0,P33897,Q9H1E5,O75947,P21912,Q9BVC6,Q9BXK5,Q8N2A8,Q9H2W6,P55061,P05067,Q12769,O15118,Q7Z434,Q9Y2R0,Q9NVH1,Q9Y619,Q13505,Q9NUQ2,P50416,P62072,Q96CU9,P05141,O95167,O00584,Q13423,Q9H4I9,P82933,Q00325,P17152,P23786,Q8N442,Q86Y39,Q9BTX1,Q9NP80,Q567V2,Q9BWH2,P23396,Q16891,Q9H9P8,Q709F0,P14406,Q9Y5Q9,P57105,Q10713,Q9NVV0,Q13057,O14657,Q9BQT8,Q9UDW1,Q9Y241,P13073,P16260,Q9BUR5,Q8NI60,P52789,Q86UE4,P12235,P22695,Q16134,Q9NZZ3,O00264,O95674,P53701,O75306,Q8WUK0,Q9UDX5,O75208,Q8N8Q8,Q9Y277,Q9NQC3,Q9NPL8,Q9H4A6,Q99643,O00165,Q7KZN9,Q8NFH5,P41208,Q9BYD1,Q9Y5J9,Q9Y6M9,Q9Y6N1,Q9BSK2,Q86UT6,Q8IXM6,Q9NZJ7,Q9BW27,Q8NBN7,Q99523,Q9UH99,Q8NFH4,Q96KC8,Q9UG56,Q9NR28,Q96AQ8,Q9P035,P30536,Q6NUM9,Q9NVI7,Q9BUB7,Q9Y5J6,Q9NX47,Q9Y5Z9,Q6DKK2,O96008,P49748,Q9P015,P24539,O43772,Q9NVS2,Q9UBM7,Q9UJZ1,P56385,P50402,P12236,Q96NB2,Q9BRJ2,Q96IX5,Q9Y512,Q5T9A4 191 +Late endosome 0.3455095988965511 0.657401673259793 0.5109226760082235 1.0 0.899279361052599 66 O95772,P07602,Q9HC07,Q15012,O15118,Q14108,Q9BUN8,Q9NZJ7,Q9Y4G8,O14653,Q96A57,P10644,Q9BXS4,Q9NZZ3,O14964,Q8IV08 16 +Organelle envelope lumen 0.3792027432975481 0.6412632863273751 0.5213516380962577 1.0 0.899279361052599 41 Q9NR28,P05067,Q9Y5J9,O14925,O00165,Q9Y5J6,O60313,P36551,P11717,Q8IYU8,Q16891,Q96AY3,O95831,Q9H4A6,P62072,Q9UJZ1,O00584 17 +Photoreceptor connecting cilium 0.5475744464571894 0.6390969281769511 0.5227598781459917 1.0 0.899279361052599 4 P41208 1 +Early endosome 0.3030336063136993 0.6372395219126089 0.5239688378649385 1.0 0.899279361052599 100 Q5VW38,Q92544,Q96A57,P31751,O14964,Q96L92,Q8N4V1,O43752,Q5T9L3,Q13510,Q9HC07,Q9Y2I1,Q9UIQ6,Q9BUN8,Q99523,Q96S38,Q99816,Q8IV08,P10321 19 +External side of plasma membrane 0.3701429670493001 0.6345540527281656 0.5257193030310405 1.0 0.899279361052599 22 P42892,P00813,O96005,P11279,P08183 5 +Gpi anchor transamidase complex 0.5025688955001625 0.6330316751141973 0.5267129584681729 1.0 0.899279361052599 5 O43292,Q9H490 2 +Lumenal side of endoplasmic reticulum membrane 0.4824880516106006 0.6285033595374429 0.5296742465469244 1.0 0.899279361052599 6 P51572,P04439,P10321,P27824 4 +Sodium potassium exchanging atpase complex 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 0.899279361052599 3 P05026,P05023 2 +Cation transporting atpase complex 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 0.899279361052599 3 P05026,P05023 2 +Atpase dependent transmembrane transport complex 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 0.899279361052599 3 P05026,P05023 2 +Endoplasmic reticulum lumen 0.3448175507563943 0.6231424122289976 0.5331909410005822 1.0 0.899279361052599 65 P05067,Q02818,Q07065,O75718,Q13217,Q9NZ08,Q8TED1,O00584,Q5JRA6,Q9BTY2,O14975,Q9Y680,Q96AY3,Q9BV10,O76024,Q32P28,Q9NWM8,P13674,Q14257,O14657,O14656,Q13438,P27824,Q9BTV4,O43852,Q6P179 26 +Dendritic spine membrane 0.7753262896208863 0.6087617915752246 0.5426823428102814 1.0 0.8997935047605048 2 P20020 1 +Extrinsic component of organelle membrane 0.4020955703386989 0.6065782578875734 0.5441308327815584 1.0 0.8997935047605048 14 Q8NI60,P62942 2 +Gamma secretase complex 0.7737725295214457 0.6038535471473963 0.5459410151189283 1.0 0.900200534120733 2 P49755 1 +Mhc protein complex 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.9016763830655112 2 P10321 1 +Mhc class i protein complex 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.9016763830655112 2 P10321 1 +Glial cell projection 0.4938378486332864 0.5961887980422316 0.5510491081778421 1.0 0.9019909672181102 5 Q8IXJ6 1 +Apical part of cell 0.3623002240172706 0.5914655525161892 0.5542085294316559 1.0 0.9040297067177776 54 Q99797,P21281,O00165,P30825,P05023,Q9Y4G8,Q86UE4,P41208,Q9Y696,P08183,P11166,Q9Y6M7,P53985,Q9ULK5,P51790 15 +Dendrite cytoplasm 0.4131788283290999 0.5880716125052705 0.5564842263324272 1.0 0.9042868677901942 11 P27824,Q9UQB8 2 +Proteasome regulatory particle lid subcomplex 0.4569915654736369 0.5658685965834801 0.5714831107456353 1.0 0.9163948325985144 7 O00231,P48556 2 +Peptidase complex 0.3493987119962233 0.5602269381933029 0.575324654904696 1.0 0.9163948325985144 60 Q15005,P49721,P48556,P28070,O00231,P61009,P60900,Q9Y6J9,P28074,P20618,P28072,P67812,Q99436,O43292,P54725,Q9H490,P61289 17 +Endoplasmic reticulum plasma membrane contact site 0.7576134244872638 0.5536742244029889 0.5798018185059646 1.0 0.9163948325985144 2 Q9NTJ5 1 +Calcium channel complex 0.4384078105818442 0.5349260621056602 0.5927009857503491 1.0 0.9193961585844532 8 Q9H4I9,P62942 2 +Cd40 receptor complex 0.7430080795525038 0.5097755276142386 0.6102087325031935 1.0 0.9254520339753164 2 Q9NR28 1 +Intrinsic component of presynaptic active zone membrane 0.5111186597112135 0.5031986643998487 0.6148246037440608 1.0 0.9254520339753164 4 Q9Y639,P27824 2 +Integral component of presynaptic active zone membrane 0.5111186597112135 0.5031986643998487 0.6148246037440608 1.0 0.9254520339753164 4 Q9Y639,P27824 2 +Transport vesicle membrane 0.3626630027538264 0.5030848973909081 0.6149045844473675 1.0 0.9254520339753164 42 Q9Y3B3,O43752,P10321,Q9NR31,P20020,Q15363,P49755,O43760,O14653,Q9Y6B6,Q15907,O76024,O60499,O75340 14 +Presynaptic active zone membrane 0.4692175834196361 0.4950132112085609 0.6205907949539844 1.0 0.9308861924309766 5 Q9Y639,P20020,P27824 3 +Caveola 0.3835575814055869 0.4920213278348906 0.6227042663300002 1.0 0.9324970398965112 14 P11166,Q8WTV0 2 +Endosome lumen 0.6070157218070233 0.4851627961765442 0.6275608703317759 1.0 0.935756031836932 3 Q9UIQ6 1 +Schmidt lanterman incisure 0.7333747669359623 0.4816403381370262 0.63006146548842 1.0 0.9360808676205652 2 Q8IXJ6 1 +Multivesicular body 0.3890657583420971 0.4721430062919804 0.6368247172959915 1.0 0.9364455269090236 12 O14964,P10644,P11279,Q9NZZ3 4 +Ciliary basal body 0.3514373647264884 0.4675682545330432 0.6400933711935979 1.0 0.9397115449437926 19 Q9P2S5,O43805,P28070,A0AVF1,O75419,P41208,P48729,Q15154,Q15691 9 +Golgi apparatus 0.4122930737788742 0.4426604423417321 0.6580113589996239 1.0 0.9520229176365116 327 Q4J6C6,Q9H8Y8,Q5VW38,P80303,O95197,P24390,Q15392,P50897,Q8N4A0,Q8N4V1,Q9Y282,Q15012,Q8NBN3,O00400,Q8NCH0,O43731,Q9NPR9,O75503,Q9P2W9,O00461,Q14108,Q9UQB8,Q5BJH7,Q8IV08,Q8N2A8,Q9Y287,Q02818,O15118,Q8TB61,P04062,Q15363,Q96A57,Q9BXS4,O60499,O95249,Q9GZM5,Q10713,Q9HC07,Q99805,Q96RQ1,Q7Z3D4,O14773,Q8TBA6,Q9BUR5,Q96JB2,Q9H2C2,O43505,Q8NF37,O15260,Q10472,Q9NQX7,P06280,O43752,Q5T9L3,Q7LGA3,Q93050,Q9NRB3,Q9NX40,Q9H4A6,Q92520,Q9Y3B3,Q7RTS9,L0R6Q1,Q9H7Z7,Q9Y3E0,O43852,Q99523,P54646,P98194,Q9H3P7,Q92544,O14653,Q7Z5K2,Q9Y5Z9,Q9UI14,P05023,Q8IZA0,O14735,Q9C0D9,O43823,Q16799,Q6NUQ4,Q9NR31,Q8N2H4,P11166,O95070,P10321,P51790 88 +Proximal dendrite 0.7169049098819205 0.435163658301169 0.6634436393334457 1.0 0.9552310505330672 2 Q6Y7W6 1 +Cell body membrane 0.7134866376631511 0.4257878979305036 0.6702624061743394 1.0 0.9594187885653056 2 P20020 1 +Immunological synapse 0.3800536552831776 0.4205931215225381 0.674052217381093 1.0 0.9594187885653056 12 Q9Y639,P10644,Q96L92 3 +Escrt i complex 0.7110006215040319 0.4190296842656615 0.6751944382794366 1.0 0.9594187885653056 2 Q99816 1 +Caspase complex 0.4240667485480084 0.4156786539758232 0.6776451631773195 1.0 0.9594187885653056 7 O43292,Q9H490 2 +Guanyl nucleotide exchange factor complex 0.4670398009950167 0.3530352015004489 0.7240620504958943 1.0 0.9873966442979318 4 Q9HAD4,Q6IAA8,Q9NR50 3 +Bcl 2 family protein complex 0.6821006836544513 0.3444047087538905 0.7305419481625663 1.0 0.9873966442979318 2 Q07820 1 +Endocytic vesicle 0.2705960513968189 0.3378345849284531 0.7354878455916474 1.0 0.9873966442979318 85 O43752,Q14108,Q03518,Q5T9L3,Q9Y4G8,P11279,Q93050,Q8WTV0,O00461,Q969Q5,Q15907,P08670,O14964,P10321,Q9Y487 15 +Kinetochore microtubule 0.3877584362444571 0.3359045193181053 0.7369428689575273 1.0 0.9873966442979318 9 P50748,Q9NZZ3 2 +Histone pre mrna 3 end processing complex 0.6743318831572223 0.325648556883627 0.7446902698817002 1.0 0.9873966442979318 2 O60506 1 +Acrosomal membrane 0.6706028589185686 0.3168516946113761 0.7513561369106614 1.0 0.989671739807435 2 P35613 1 +Astrocyte projection 0.6681168427594718 0.3110625081170566 0.7557531023832618 1.0 0.989956317451788 2 P05067 1 +Cytoplasmic ubiquitin ligase complex 0.3821943996190352 0.3097172951925402 0.7567759494106157 1.0 0.989956317451788 9 Q9BUN8,Q13438,Q9UBU6,Q9Y679 4 +Membrane protein complex 0.3915590608001907 0.2872599630906172 0.7739132761170122 1.0 0.9959442735152304 300 O43676,P03886,Q8IYU8,O14949,P00846,O60830,P21796,Q8N4V1,O95139,O00560,Q8N511,Q9NS69,Q9Y584,O75964,Q9C0H2,Q07666,O75431,Q5HYI7,P45880,Q8N4H5,Q96ER9,Q6UXV4,P61009,P49755,Q13438,Q99595,Q9P2W9,O14548,Q9NX14,O14925,O75251,Q9BUN8,P67812,Q5XKP0,P21912,O75947,Q4KMQ2,Q9NVH1,P49458,Q13505,Q9UGP8,P62072,Q96CU9,P05141,O95167,O60499,O75340,P51798,Q9H4I9,Q53GQ0,Q86Y39,O95249,Q16891,Q9Y6B6,P14406,Q9UBV2,Q15904,Q92643,Q13546,Q9UDW1,P08195,O75787,P13073,Q92542,O43292,Q9BUR5,P04439,Q9H270,Q15388,P12235,P22695,Q03518,Q9NPA0,Q9Y679,P62942,O75306,O43752,Q9Y277,Q93050,Q99643,Q9Y487,Q9Y3B3,Q9Y696,Q9Y6M9,Q15005,Q9UH99,Q9Y5M8,Q9H490,Q9NR28,P21281,O14653,Q9Y5J6,P05023,O15269,O96008,P63096,P24539,Q9UBU6,P51571,P56385,P12236,Q9NR31,P46977,Q96IX5,Q9Y512,Q99816,Q15041,P10321 108 +Cul4a ring e3 ubiquitin ligase complex 0.5343487721479727 0.2851780047131639 0.7755077706942537 1.0 0.9959442735152304 3 Q92990,Q16531 2 +Nuclear membrane 0.2840931124175636 0.2744474997114758 0.7837407442570801 1.0 0.9959442735152304 109 Q5SNT2,Q9P035,Q6NUM9,Q15154,P62995,O75844,Q9BTX1,Q14739,Q99720,Q9H2V7,O00165,Q8NFH5,Q9UBM7,Q8IXM6,P50402,Q9BW27,Q5BJF2,Q86UE4,Q99523,Q9UH99,Q9H1E5,Q96KC8 22 +Messenger ribonucleoprotein complex 0.3976185641414888 0.2340586610814307 0.8149394382432009 1.0 1.0 5 P51991 1 +Anaphase promoting complex 0.3653475043200656 0.2332539668873384 0.8155642018239952 1.0 1.0 9 P30260,O60566,Q96DE5,Q9UJX4 4 +Membrane microdomain 0.3144559877687837 0.2251285366411735 0.8218792817115348 1.0 1.0 61 P09601,Q9UJZ1,P35613,P05067,O15118,O00560,P05023,P21796,P13473,P11166,P10644,Q8WTV0,O14773,P05141,P27105,P20020,P50897 17 +Dendritic growth cone 0.4181597649436073 0.2116059327884687 0.8324144804494815 1.0 1.0 4 Q9UL54 1 +Dendrite terminus 0.4181597649436073 0.2116059327884687 0.8324144804494815 1.0 1.0 4 Q9UL54 1 +Mcrd mediated mrna stability complex 0.4163078658785771 0.2068685484394133 0.8361125198965722 1.0 1.0 4 O60506 1 +Late endosome membrane 0.3249223883192914 0.2035688728929307 0.8386904195964597 1.0 1.0 37 O95772,Q9HC07,Q15012,O15118,Q14108,P11279,O14653,Q9BXS4,Q9NZZ3,Q99816,O14964,Q8IV08 12 +Nuclear envelope lumen 0.3738079100444371 0.1625119265236237 0.8709027371109661 1.0 1.0 5 P05067,P11717 2 +Schaffer collateral ca1 synapse 0.320493079824081 0.1368975801123885 0.8911117516193303 1.0 1.0 14 Q9Y639,Q9UQB8 2 +External encapsulating structure 0.3091784804763668 0.1301391010616257 0.8964563749822714 1.0 1.0 30 Q08380,P84157,P07602,Q53GQ0 4 +Juxtaparanode region of axon 0.3818890518491408 0.1280287538336029 0.8981262180184721 1.0 1.0 4 Q8IXJ6 1 +Manchette 0.5571783716594284 0.1186645786158649 0.905541100380192 1.0 1.0 2 Q96SI9 1 +Checkpoint clamp complex 0.5550031075202118 0.1161978057736941 0.907495775713252 1.0 1.0 2 O60921 1 +Pronucleus 0.3523134321714796 0.106106157835694 0.9154981254831028 1.0 1.0 5 O43823 1 +Female pronucleus 0.3523134321714796 0.106106157835694 0.9154981254831028 1.0 1.0 5 O43823 1 +Chromaffin granule membrane 0.5431945307644632 0.1036325571376317 0.9174609499015188 1.0 1.0 2 P30626 1 +Chromaffin granule 0.5431945307644632 0.1036325571376317 0.9174609499015188 1.0 1.0 2 P30626 1 +Postsynaptic endosome 0.4351880634131255 0.1027587128657781 0.918154474096563 1.0 1.0 3 Q86Y82,P20339 2 +Tertiary granule membrane 0.3181575457173429 0.1008495370350174 0.9196699023943882 1.0 1.0 12 Q4KMQ2,P10253,Q08722,P27105 4 +Coated vesicle membrane 0.3053628479699393 0.093019919057659 0.925887736711061 1.0 1.0 57 Q8N511,P24390,O43731,Q14108 4 +Basal cortex 0.5310752019888234 0.0921435306169147 0.9265840031111848 1.0 1.0 2 Q7Z460 1 +Spectrin 0.4236866645943521 0.0890756543313245 0.9290217854972148 1.0 1.0 3 Q01082,Q13813 2 +Spectrin associated cytoskeleton 0.4227541187441784 0.0880317941672405 0.929851406139063 1.0 1.0 3 Q01082,Q12955 2 +Hippocampal mossy fiber to ca3 synapse 0.4208890270438378 0.0859731646353733 0.9314877497414124 1.0 1.0 3 O60716,P47756 2 +Copii vesicle coat 0.3220479334891686 0.0806455638642654 0.9357238294644584 1.0 1.0 10 Q9NR31,Q9Y3B3,O75340 3 +Collagen trimer 0.5087010565568826 0.0744374277540231 0.940662328356268 1.0 1.0 2 Q5KU26 1 +Saga complex 0.4079648897361544 0.0727541488735467 0.9420017581090614 1.0 1.0 3 Q9Y6J9 1 +Endopeptidase complex 0.3061748281831978 0.071394761235072 0.9430835789006864 1.0 1.0 53 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,O43292,P54725,Q9H490,P61289 12 +Chromocenter 0.3922909543052573 0.0590755751803369 0.9528919128394248 1.0 1.0 3 P83916,Q06787 2 +Esc e z complex 0.38545228473734 0.0538700109159325 0.9570387297815068 1.0 1.0 3 Q16576,Q15022 2 +Presynapse 0.2551543587462836 0.0514031958388169 0.9590042382307216 1.0 1.0 92 Q9BT78,O43752,Q9UI14,Q9Y639,P11279,Q13641,Q9UQB8,P11166,O43760,Q96A57,P27824,P07196,Q15907,O76024,O60499,P50897 16 +Dense core granule 0.4636420136731056 0.050610468098533 0.9596359211806064 1.0 1.0 2 Q96RL7 1 +Neuronal dense core vesicle 0.4636420136731056 0.050610468098533 0.9596359211806064 1.0 1.0 2 Q96RL7 1 +Pcg protein complex 0.3245177349097691 0.0470050459731393 0.9625092058709483 1.0 1.0 6 Q9UQR0,Q16576,Q14157,Q92769,Q15022 5 +Rna polymerase iii transcription regulator complex 0.3305348258706388 0.0442678008738435 0.9646909376830388 1.0 1.0 4 Q8WUA4,Q9Y5Q9,Q9Y5Q8 3 +Transcription factor tfiiic complex 0.3305348258706388 0.0442678008738435 0.9646909376830388 1.0 1.0 4 Q8WUA4,Q9Y5Q9,Q9Y5Q8 3 +T tubule 0.3227472845981684 0.0436975820362197 0.9651454666330864 1.0 1.0 7 P05023 1 +Rnai effector complex 0.3222395023328038 0.0412927682065766 0.9670624982900312 1.0 1.0 5 Q08211,P06730,P26196,Q9HAV4 4 +Cuticular plate 0.3527035425730419 0.0321979956068116 0.9743141546259262 1.0 1.0 2 Q01082 1 +Extrinsic component of postsynaptic specialization membrane 0.3455562461156103 0.0319431916731622 0.9745173542254648 1.0 1.0 2 P52292 1 +Extrinsic component of postsynaptic membrane 0.345663661796712 0.0316194279201569 0.9747755498957944 1.0 1.0 3 P52292,P46109 2 +Dopaminergic synapse 0.2970789310130641 0.0311217572985778 0.975172438257256 1.0 1.0 2 O75955 1 +Cell pole 0.3362555391696471 0.0280784521751258 0.9775995799701316 1.0 1.0 3 P08195 1 +Proteasome complex 0.3029449341431426 0.0277977903984608 0.977823428289627 1.0 1.0 45 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P54725,P61289 10 +Plasma membrane raft 0.2799617200678806 0.0222355619907012 0.9822600502305248 1.0 1.0 19 P11166,P10644,Q8WTV0 3 +Phagocytic vesicle 0.3015881703946386 0.0188147572444771 0.9849888813283204 1.0 1.0 44 O43752,Q03518,P51790,P11279,Q93050,P61026,Q15907,P08670,O14964,P10321,Q9Y487 11 +Neuron projection terminus 0.2903129718548881 0.0085727426241513 0.9931600247970362 1.0 1.0 15 Q13641,Q9UQB8 2 +Lateral plasma membrane 0.2720819417192857 0.0030765202194747 0.99754529588817 1.0 1.0 20 Q9ULK5,P05023,Q8TAA9 3 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5fc7110128d90c1db2bd51c0e167b9f61bd16237 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATG3", "ATG7", "ATG9A", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCS1L", "BIRC6", "BMS1", "BNIP1", "BOP1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf43", "C14orf2", "C17orf75", "C18orf32", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "CAB39", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CASK", "CAST", "CBL", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPP", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD4", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTC", "CMPK1", "CNN2", "CNN3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG4", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPAGT1", "DPF2", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA1", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISCU", "ISOC1", "IST1", "ISY1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "IVD", "JAGN1", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRWD1", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "LYSMD3", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL13", "METTL14", "METTL3", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1", "PAK2", "PALLD", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PECR", "PEF1", "PELP1", "PES1", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF40", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A1", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM223", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOR3A", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRMT10C", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN10", "TSPAN3", "TSPAN6", "TSPO", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNG", "TXN2", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "ULK3", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VANGL2", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VKORC1L1", "VMA21", "VPS11", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WASF2", "WASHC2A", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ACAD11", "ACADVL", "ACBD3", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACSL6", "ACTR1A", "ADA", "ADPGK", "AGPAT5", "AGTRAP", "AHSA1", "AIFM1", "AKAP8", "AKT2", "ALDH3A2", "ALG1", "ALG12", "ANAPC16", "ANAPC5", "ANK3", "ANKLE2", "ANO6", "APOL2", "APOO", "APOOL", "APP", "ARL6IP1", "ARL6IP5", "ARMCX3", "ARV1", "ASAH1", "ASPH", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "AUP1", "B4GAT1", "BAIAP2", "BCAP31", "BCL2L13", "BRI3BP", "BSG", "BUB1B", "C18orf32", "C19orf70", "CALU", "CANX", "CAPZB", "CBX1", "CCDC47", "CCDC51", "CD47", "CDC27", "CDC45", "CDIPT", "CDKAL1", "CDS2", "CERS1", "CERS2", "CETN2", "CHMP5", "CHORDC1", "CHST12", "CHST14", "CISD1", "CKAP4", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLIC4", "CLN5", "CLPTM1", "COA3", "COASY", "COG3", "COLEC12", "COPS4", "COQ8A", "COQ9", "COX11", "COX15", "COX16", "COX18", "COX4I1", "COX5A", "COX6C", "COX7A2", "COX7A2L", "CPOX", "CPSF6", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK1A1", "CTNND1", "CTSA", "CYB5B", "CYP51A1", "DAGLB", "DCTN3", "DCTN4", "DDB1", "DDHD2", "DDRGK1", "DDX6", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHRS1", "DHX9", "DIABLO", "DNAJC1", "DNAJC11", "DNAJC3", "DOLPP1", "DYM", "EBP", "ECE1", "EIF2B3", "EIF4E", "EMC7", "EMD", "ERAP1", "ERAP2", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "ESYT2", "ETFDH", "EXTL3", "FADS2", "FAM162A", "FAM3C", "FAM49B", "FAM8A1", "FKBP10", "FKBP14", "FKBP1A", "FKBP7", "FLOT1", "FMR1", "FOXRED1", "FUCA1", "FUCA2", "FUNDC2", "GAA", "GALNT1", "GALNT4", "GBA", "GGCX", "GHITM", "GIGYF2", "GINS2", "GLA", "GLB1", "GLMN", "GM2A", "GNAI1", "GNPAT", "GOLGA5", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPAA1", "GPR107", "GPR108", "GPR89B", "GPX8", "GTF3C2", "GTF3C3", "GTF3C5", "GUF1", "HACD2", "HACD3", "HAUS4", "HAUS5", "HAX1", "HCCS", "HDAC2", "HEXA", "HGS", "HIGD1A", "HK2", "HLA-A", "HLA-C", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPR", "HS2ST1", "HSD17B12", "HSPA13", "HUS1", "ICMT", "IGF2R", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "ISOC1", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KHDRBS1", "KIAA0319L", "KNTC1", "KPNA2", "L2HGDH", "LAMP1", "LAMP2", "LAMTOR1", "LAPTM4A", "LBR", "LGALS3BP", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "LPCAT3", "LRRC59", "LSS", "LYSMD3", "M6PR", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MAVS", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM6", "MCUR1", "MFF", "MFN1", "MIA2", "MIA3", "MICU2", "MIPEP", "MMGT1", "MOB4", "MPP2", "MPV17L2", "MRPL13", "MRPL15", "MRPL20", "MRPL45", "MRPL46", "MRPL47", "MRPL55", "MRPS18A", "MRPS9", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX2", "MTX3", "MXRA7", "MYO19", "NAGLU", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA3", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB9", "NDUFS2", "NDUFS7", "NEFL", "NEFM", "NENF", "NISCH", "NLRX1", "NNT", "NONO", "NPC1", "NPTN", "NRM", "NUCB1", "NUCB2", "NUP160", "NUP35", "NUP37", "NUP85", "NUP93", "NXF1", "OCIAD1", "OLA1", "OPA1", "OS9", "OXA1L", "P3H1", "P3H4", "P4HA1", "PARL", "PCM1", "PCYOX1", "PCYOX1L", "PDCD6", "PEX11A", "PEX11G", "PEX14", "PEX16", "PEX3", "PEX5", "PGAM5", "PGRMC1", "PGRMC2", "PIGK", "PIGL", "PIGU", "PISD", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PMPCA", "PNPLA8", "PON2", "POR", "PPT1", "PPT2", "PRCP", "PREB", "PREPL", "PRKAA2", "PRKAR1A", "PSAP", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSMD8", "PSME3", "PSPC1", "PTDSS2", "PTGES2", "PTPMT1", "PTPRF", "PXMP2", "RAB10", "RAB11B", "RAB24", "RAB5A", "RABAC1", "RAD23A", "RAPGEF2", "RBBP7", "RBP1", "RCN2", "RDH13", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RETSAT", "RIPK1", "RMDN3", "RNASET2", "RPS3", "RPS6KC1", "RTN1", "RTN2", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SAR1B", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SDCBP", "SDHB", "SDHC", "SEC11A", "SEC62", "SEC63", "SEL1L", 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0.0012144027622474 1.4917453751448747e-05 +Metalloendopeptidase activity 5 14 2.886583427301934 0.0038944948278816 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.003007131926098 0.1499686155438198 0.2780273254227372 0.0078094686864188 0.0045924061823516 +Protein transporter activity 13 16 2.881217142925332 0.0039614262152152 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 8.322368656265211e-05 0.0002365528693072 1.1653357867839908e-07 2.2359581100408143e-05 1.4175664763662648e-06 +Secondary active transmembrane transporter activity 14 23 2.809743141907203 0.0049581052455847 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.0518488850424092 0.3523884632837075 0.5815024054643041 0.0194272316030456 0.0100189635560291 +Nucleobase containing compound transmembrane transporter activity 12 14 2.759887940349536 0.0057821191202585 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.0155746476830001 0.1457663642848915 0.27085351108605 0.0069928111010265 0.0007105677029561 +Anion transmembrane transporter activity 27 46 2.714933938956181 0.0066288992037264 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 0.0001188938805975 0.1267011687502946 0.0078713338334775 5.078931708252657e-05 3.511391403057467e-05 +Organic acid transmembrane transporter activity 10 24 2.711693238065972 0.0066940510750232 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0045245212935941 1.0 0.1434310184114938 0.0012097891796545 0.0015271087737537 +Inorganic anion transmembrane transporter activity 7 18 2.691521221840763 0.0071126972907522 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0047982913038071 0.2260688267312995 0.0142951840993497 0.0081044088621321 0.0033296386804888 +Alcohol binding 8 17 2.664845843579728 0.0077023621769047 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0039402001099595 0.2183837422916212 0.0861587362261736 0.001212131153867 0.0005879318152671 +Protein transmembrane transporter activity 4 12 2.663715225742053 0.0077282956131226 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0001169558798128 7.189730386960826e-05 4.6250912861383714e-07 3.830880641039723e-05 9.937036022358197e-05 +Macromolecule transmembrane transporter activity 11 13 2.652780394457782 0.0079831791350142 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0002717646605189 0.0001192904084611 1.132066507822963e-06 9.045491853019026e-05 0.0002747300414667 +Nucleotide transmembrane transporter activity 10 12 2.5948300098564285 0.0094637712400529 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 0.0033695122551162 0.0981765691424607 0.1871299927573601 0.0014320459890063 0.0003689915939861 +Organophosphate ester transmembrane transporter activity 10 12 2.5948300098564285 0.0094637712400529 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.0040207313875964 0.1026081339138497 0.1951188871774342 0.0017174581383874 0.0004867641084232 +Membrane insertase activity 4 11 2.558937479124914 0.0104992621980057 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 4.080638129697421e-05 0.066549445548378 0.0080257871552124 0.0041470760753771 0.0003671727016274 +Sterol binding 6 16 2.493419071539578 0.0126519422158029 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0044339660591253 0.1624541869963563 0.0483495219963649 0.0016056440309417 0.0014896299843671 +Glycolipid binding 5 8 2.4863676678483926 0.0129054556723049 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 0.0014751616716224 0.0802348466038066 0.0117676307173903 0.0006143549700213 9.937036022358197e-05 +Peptide binding 14 71 2.4852187183726877 0.0129471860079257 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 4.095552332585046e-05 0.0351600240262175 0.0031807675007041 0.0002237177417525 0.0020342884965043 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 12 28 2.474276144822955 0.0133506458526111 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.1543333474103733 0.3682511930157578 0.2316260817282189 0.0740089890485984 0.0817388517598971 +Protein carrier chaperone 4 14 2.457482065275018 0.0139914796687143 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 0.0001579195479637 0.0847528009868792 0.0131546828557762 0.0086586519898169 0.0013369974246366 +Serine type carboxypeptidase activity 3 5 2.450047760745011 0.014283726687754 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 4.145186531543548e-06 0.0242848323540905 9.025666232893031e-06 1.6228361660218084e-06 2.639864710894744e-05 +Cholesterol binding 6 13 2.419801618287611 0.015528976348994 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0019454827870102 0.1373006943976843 0.0346664630686661 0.0006827439557333 0.0004675519327548 +Exopeptidase activity 10 34 2.4173322582154877 0.0156347383375026 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 1.909530091969719e-06 0.0032700867405931 2.747918391652972e-05 1.8588942110655865e-07 2.9640015944659375e-05 +Phosphatidylcholine binding 2 7 2.4164935081471635 0.0156708056728092 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0117182537853428 0.0756950383436983 0.0104494791604543 0.0061570039439817 0.0397387250697101 +Sulfur compound transmembrane transporter activity 3 7 2.4048881029377704 0.016177418371202 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0110460269750891 0.0087935329278829 0.0325598174288622 0.0048864602536943 0.0498364179528963 +Active ion transmembrane transporter activity 21 41 2.402942230668028 0.0162637564691381 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.0689958360186826 0.4420266901261166 0.3224853892114088 0.0239861063430982 0.0005671525901641 +Serine type exopeptidase activity 4 7 2.386520508516484 0.0170086586730693 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 2.9136663587575637e-06 0.0432957136582515 7.367718167669133e-05 9.14133433735114e-07 2.8311070051942505e-05 +Anion channel activity 9 12 2.3853306894038755 0.0170637749461961 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0014102786979957 0.1287528218161406 0.002509898486982 0.0042924995678 0.001918269568256 +Gated channel activity 11 14 2.3847438934496967 0.0170910148901939 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.0356511886847883 0.2560754722464486 0.0209290225413289 0.0564393829037643 0.0698685551762488 +Proton transmembrane transporter activity 18 37 2.374289849997389 0.0175827419081604 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 0.0003937031030927 0.0056332205677222 0.0359624367366125 0.0003907769995998 1.0438111343814942e-05 +Antiporter activity 8 11 2.3558643014028564 0.0184796669827462 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.0301995022754788 1.0 1.0 0.0140312853386763 0.0390278099301106 +Sphingolipid binding 3 6 2.35567645405481 0.0184890135699551 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0163255392019355 0.0847528009868792 0.0006712136127385 0.0086586519898169 0.0097510399506001 +Carbohydrate derivative transmembrane transporter activity 8 10 2.336640111288066 0.0194579049626013 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 0.0435317720090838 0.1201219647894398 0.2263045436956677 0.0239571113561098 0.0074494564855197 +Fad binding 5 11 2.334553170966509 0.0195667753351813 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0435317720090838 0.1201219647894398 0.0265618978442646 0.0239571113561098 0.0074494564855197 +Organic anion transmembrane transporter activity 17 31 2.3160846934835697 0.0205536448710668 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0042958002485272 0.3426841548479852 0.2027827245191691 0.0009941384248502 0.0007767330813302 +Passive transmembrane transporter activity 19 37 2.2543933992171734 0.0241714301809017 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.0595273170630676 0.0182301376254106 0.0051863919477672 0.0575259106236958 0.0091850044185398 +Voltage gated channel activity 8 10 2.246329851967919 0.0246828878271365 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0191572938808404 0.1541506060207377 0.0435975481844182 0.0479498850625808 0.0229507437408614 +Monooxygenase activity 6 10 2.2436538849892287 0.0248546793541359 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0011877087888605 0.1244478155008913 0.0285062952815799 0.0004102788019959 0.0015706126808535 +Palmitoyl protein hydrolase activity 2 7 2.2359303383681284 0.0253563346506797 1.91747572815534 5.429611650485437 0.9780254626091984 0.222941388490727 1.137611804765983 0.8139540579221628 1.3123017012345466 0.2566673774233151 0.0050382705358123 0.0573151884822011 0.0058956460302812 0.0025975272437437 0.018020673376298 +Threonine type peptidase activity 5 8 2.234349168086861 0.0254601075386344 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.0079677731040502 0.066549445548378 0.1289666473793992 0.0435926191526008 0.0003671727016274 +Threonine type endopeptidase activity 5 8 2.234349168086861 0.0254601075386344 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0028755778106474 0.0479914252810258 0.0938999510605359 0.0229613270793894 5.436360967141595e-05 +O acyltransferase activity 9 15 2.210036138935952 0.0271026542829748 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.0026157118857966 0.1457663642848915 0.27085351108605 0.0069928111010265 0.0007105677029561 +Amide binding 24 103 2.194596461464658 0.028192557609846 22.521844660194176 102.53398058252426 0.8716704131409604 0.4134472412494542 7.596116055031058 7.786365397071367 1.2519470693533183 0.3815633057547212 1.2113085559647514e-06 0.0180648926896899 0.0001829158898512 9.716255438017107e-06 2.26974962868853e-06 +Metallopeptidase activity 11 43 2.191262801483832 0.0284327802833719 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 0.0001496929014378 0.0584635742500571 0.0437228444640497 0.0001247279452058 0.0004431313439272 +Acylglycerol o acyltransferase activity 4 10 2.187960819802861 0.028672456402206 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.0033695122551162 0.0981765691424607 0.1871299927573601 0.0133829456596615 0.0028145739091465 +Purine nucleotide transmembrane transporter activity 7 9 2.179576893786621 0.029288839114927 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 0.0117182537853428 0.0756950383436983 0.1459927402947744 0.0061570039439817 0.0062633876942655 +Metalloexopeptidase activity 6 22 2.164007366895576 0.0304637840201882 5.395631067961165 20.067961165048544 0.9825976981990544 0.3457114951896768 2.1791777953827336 1.4039620491256346 0.996651753778752 0.2995335114577974 0.000590000140569 0.012648542478749 0.0047719907059414 0.000167417985794 0.0012514150662819 +Hydrolase activity hydrolyzing o glycosyl compounds 8 19 2.1454022663965397 0.031920698056385 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 8.917547480663806e-05 1.0 1.0 0.1089349903226686 0.0004290006789134 +Amyloid beta binding 3 10 2.128282287954556 0.0333136857341893 3.5898058252427183 10.560679611650484 1.053866189591651 0.2544642672774957 2.009490338022764 1.9342863324228672 1.0942484681219342 0.2534200432416059 0.0254176145400096 1.0 0.3060304729743218 0.224257489169728 0.1028731839020021 +Lipid binding 35 135 2.1093425103943653 0.0349150279320096 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0053652082450115 0.1769838899728609 0.0124480366702801 0.0028166307001182 0.0010897343598396 +Voltage gated anion channel activity 6 7 2.108067439367006 0.035025156414747 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0001541627914423 0.0479914252810258 0.004071454093033 0.0014684283121974 0.0009118158302113 +Cargo receptor activity 3 7 2.1071340780886545 0.0351059591357982 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0524814200598482 1.0 0.2414457297612108 0.1457934990596532 0.0446088038944012 +Quaternary ammonium group binding 3 11 2.0777882267821663 0.0377288686681114 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0040207313875964 0.1026081339138497 0.0193632099375005 0.0017174581383874 0.0200033311952484 +Serine hydrolase activity 7 21 2.037228327384915 0.0416271663773093 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 8.917547480663806e-05 0.2106238865633207 0.0012175599782738 0.0001382861626823 0.0019780921583714 +Hydrolase activity acting on glycosyl bonds 9 26 2.016360862027584 0.0437622549553906 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 0.0003551558384187 1.0 0.5142525268330266 0.0994768290011166 0.0026289561565188 +Vitamin transmembrane transporter activity 4 6 2.0125729111543267 0.0441595791435192 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0189572928019038 1.0 1.0 0.0101015401572799 0.0618109910728358 +Sterol transporter activity 2 8 2.012067360099674 0.0442128367983734 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.1545530381620926 1.0 1.0 0.1053546389470493 0.0981468657129251 +Symporter activity 4 10 2.00982581250078 0.0444496278223516 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 0.390105690092614 0.1948770046367652 0.3524722176470324 0.2871762535363917 0.0605931687414638 +Peptidase activity 26 116 2.002309154378044 0.045251492059043 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 9.58982753057533e-06 0.0542732260417351 0.0022285707236609 7.591467828762224e-06 0.000192800308981 +Amide transmembrane transporter activity 2 6 1.986062652716236 0.0470263675581785 1.9781553398058251 4.745145631067961 1.408683964326367 0.195466717632665 1.3391087077639925 1.811666809674734 1.0002201259794938 0.2223338014085611 0.0218096458546513 0.0937235599037543 0.179062604831997 0.0828772873031817 0.0701952648708137 +Amino acid transmembrane transporter activity 4 13 1.9801939384066636 0.0476817407286429 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.1218502511695123 1.0 0.0583817580096799 0.0713646261968556 0.0428945912137629 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..833884ab615d12b3fb66843639ff976e5b96f7aa --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 1373, + "title": "Average number of proteins per term", + "value": 16.41879096868172 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..16bdd4846d2188ad9c4f9a0e00188a83ee3aba15 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..018f81a041960b44240afe544831c8c6179bfb4a --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,376 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ion transmembrane transporter activity 0.5841268840242265 4.155576440186493 3.244684385550478e-05 0.0435724514355361 0.0445495166136094 104 P98194,P21281,Q4KMQ2,Q8TB61,Q70HW3,Q9Y619,Q9HC21,P00846,P21796,P05141,P51798,Q8N4V1,Q13423,Q00325,O00400,Q9NW15,Q9Y277,P05023,O75964,Q93050,Q9C0H2,Q9Y6M7,P45880,P20020,O43808,Q9Y487,Q9NVV0,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,Q9BQT8,Q9UDW1,Q7KZN9,Q9Y696,O43772,P08195,P13073,O14548,P16615,P53985,Q9HD20,Q6P4A7,P0CG08,P56385,P12236,Q96NB2,Q9UBX3,Q9H2D1,P12235,Q6NUK1,P11166,Q96ES6,O75947,Q9BVC6,P51790 57 +Inorganic molecular entity transmembrane transporter activity 0.605918548778841 3.964218502876755 7.363678220251302e-05 0.096163705015621 0.0505516509820258 76 Q99797,P98194,P21281,Q4KMQ2,P00846,P21796,P05141,P51798,Q8N4V1,Q13423,Q00325,O00400,Q9NW15,P05023,Q9Y277,Q93050,O75964,Q9C0H2,Q9Y6M7,P45880,P20020,Q9Y487,Q9NVV0,Q96ER9,Q9HC07,P24539,Q9H2J7,Q7KZN9,Q9UDW1,Q9Y696,P08195,P13073,P16615,O14548,Q9HD20,P56385,P0CG08,Q9UBX3,P12235,Q96ES6,O75947,P51790 42 +Cation transmembrane transporter activity 0.586291297870693 3.556981045266126 0.0003751412126948 0.4025982960824578 0.117734329380706 73 P98194,P21281,Q4KMQ2,Q70HW3,Q9Y619,Q9HC21,P00846,P05141,Q8N4V1,Q13423,Q00325,O00400,Q9NW15,P05023,Q93050,O75964,Q9Y6M7,P20020,Q9Y487,O43808,Q9NVV0,Q96ER9,Q9HC07,P30825,P24539,Q9H2J7,Q7KZN9,Q9UDW1,O43772,P08195,P13073,P16615,O14548,Q9HD20,P56385,Q96NB2,P12235,Q96ES6,O75947,P51790 40 +Transporter activity 0.5807555029893188 3.4853826300785915 0.0004914337627008 0.4907949043496499 0.117734329380706 183 O43676,P03886,Q70HW3,P51991,Q9HC21,P17900,P00846,O60830,P21796,Q8N4V1,O95139,O00400,O14975,Q9NS69,Q9Y584,O75964,Q9C0H2,Q8WTV0,P45880,Q96ER9,Q9H2V7,P30825,Q96H78,O15173,P49755,O75027,Q99595,O14548,Q9HD20,Q6P4A7,O14925,O75251,Q9UBX3,Q9H2D1,Q6NUK1,P33897,O75947,Q9BVC6,O15118,Q4KMQ2,Q8TB61,P04062,Q9Y619,Q9UGP8,P05141,O95167,P51798,Q8NHS3,Q13423,Q00325,Q9NW15,P20020,O43808,Q9HC07,Q9BQT8,Q9UDW1,P13073,P16260,P38435,Q9H2C2,P12235,P08183,Q96ES6,Q8IXU6,Q03518,O75306,Q9Y277,Q93050,Q9Y6M7,Q8NE01,Q9Y487,Q7KZN9,Q9Y696,L0R6Q1,P16615,Q9Y5J9,Q9Y6M9,Q9BSK2,Q99797,P98194,P21281,P30536,Q9Y5J6,P05023,O96008,P24539,Q9H2J7,O43772,P53985,P56385,P12236,Q96NB2,P11166,P51790 94 +Tetrapyrrole binding 0.7988168729097485 3.4730924162444814 0.0005144981618967 0.5066753295411618 0.117734329380706 19 Q16850,Q9H7Z7,Q7KZN9,O15173,P30519,Q6UW02,O43169,Q8WUJ1,Q9NRV9,P53701,Q99643,O00264 12 +Steroid binding 0.7381098269688233 3.230894184393852 0.0012340361560922 0.8164701466994306 0.2420473774735327 21 O95772,Q14108,P38435,O15118,P04062,O15173,P35610,P30536,P45880,P21796,O00264 11 +Active transmembrane transporter activity 0.5177292146576664 3.1312929114175887 0.0017403848130845 0.9085195628268196 0.2895181747966237 77 O43676,P98194,P21281,P03886,Q03518,P05141,O95167,P51798,O75306,Q00325,O95139,O00400,P05023,Q9Y6M7,P20020,Q9H2J7,Q7KZN9,Q9UDW1,O75027,P08195,P13073,O14548,P16615,P16260,Q9HD20,Q9Y6M9,P53985,O95202,O75251,P12236,Q9UBX3,P12235,P08183,Q96ES6,P33897,P51790 36 +Metalloendopeptidase activity 0.7790323684607767 2.886583427301934 0.0038944948278816 0.9952877073099414 0.4264314688127621 14 O43847,P42892,Q10713,O75844,P22695 5 +Protein transporter activity 0.7481744633483081 2.881217142925332 0.0039614262152152 0.9957030074328024 0.4264314688127621 16 O14925,Q9HD20,Q15388,Q9NS69,O96008,Q9Y584,P49755,O94826,Q99595,Q9UGP8,Q9Y5J9,Q9Y5J6,O60830 13 +Secondary active transmembrane transporter activity 0.6707270221784108 2.809743141907203 0.0049581052455847 0.9989130836081166 0.4264314688127621 23 P51798,Q00325,P12236,Q9UBX3,O00400,Q9H2J7,P53985,P12235,Q96ES6,P08195,Q9Y6M7,P16260,P05141,P51790 14 +Nucleobase containing compound transmembrane transporter activity 0.7557663112434172 2.759887940349536 0.0057821191202585 0.9996515061926592 0.4264314688127621 14 P12236,O00400,Q8TB61,Q9H2D1,P51991,P12235,Q6NUK1,Q9HC21,L0R6Q1,P33897,Q9BSK2,P05141 12 +Anion transmembrane transporter activity 0.6187347246147458 2.7149339389561815 0.0066288992037264 0.9998918270235728 0.4264314688127621 46 Q4KMQ2,Q8TB61,Q9Y619,Q9HC21,P05141,P21796,P51798,O00400,Q9NW15,Q9Y277,Q9C0H2,Q9Y6M7,P45880,O43808,P30825,Q9BQT8,Q9Y696,P08195,P53985,P12236,Q96NB2,Q9UBX3,Q9H2D1,P12235,Q6NUK1,P11166,P51790 27 +Organic acid transmembrane transporter activity 0.6554060314160007 2.7116932380659717 0.0066940510750232 0.9999011426233414 0.4264314688127621 24 Q96NB2,P30825,Q9UBX3,Q96H78,Q9H2J7,Q9H2D1,Q9BQT8,Q9Y619,P08183,P53985 10 +Inorganic anion transmembrane transporter activity 0.6852275801274712 2.691521221840763 0.0071126972907522 0.999944583285323 0.4264314688127621 18 P51798,Q9UBX3,Q9Y277,Q9C0H2,Q9Y6M7,P45880,P21796 7 +Alcohol binding 0.6960080909406935 2.664845843579728 0.0077023621769047 0.9999754863677988 0.4264314688127621 17 O95772,Q14108,O15118,P35610,P30536,P09455,P45880,P21796 8 +Protein transmembrane transporter activity 0.7643558175908779 2.663715225742053 0.0077282956131226 0.999976350406691 0.4264314688127621 12 Q9Y584,O60830,Q99595,Q9NS69 4 +Macromolecule transmembrane transporter activity 0.749567518413106 2.652780394457782 0.0079831791350142 0.9999833797817976 0.4264314688127621 13 O14925,P51991,Q15388,Q9NS69,O96008,Q9Y584,P49755,O94826,Q99595,Q9UGP8,O60830 11 +Nucleotide transmembrane transporter activity 0.751399181178917 2.5948300098564285 0.0094637712400529 0.9999978619868248 0.4264314688127621 12 P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 10 +Organophosphate ester transmembrane transporter activity 0.751399181178917 2.5948300098564285 0.0094637712400529 0.9999978619868248 0.4264314688127621 12 P12236,O00400,Q8TB61,Q9H2D1,P12235,Q6NUK1,Q9HC21,P33897,Q9BSK2,P05141 10 +Membrane insertase activity 0.7565448718593065 2.558937479124914 0.0104992621980057 0.9999994914472488 0.4264314688127621 11 Q15070,Q8N4V1,P62072,Q9NPA0 4 +Sterol binding 0.6816085212150982 2.493419071539578 0.0126519422158029 0.9999999744324432 0.4264314688127621 16 O95772,Q14108,O15118,P35610,P45880,P21796 6 +Glycolipid binding 0.8266585823387309 2.4863676678483926 0.0129054556723049 0.9999999820292624 0.4264314688127621 8 P07602,Q9NZJ7,O14773,O43292,P50897 5 +Peptide binding 0.4925346855096832 2.4852187183726873 0.0129471860079257 0.9999999830426956 0.4264314688127621 71 Q9Y287,P42892,Q9UIQ6,Q03518,Q9Y584,O43731,Q8WTV0,Q9UHB9,Q9NZ08,P55786,O14773,P24390,Q15392,O00264 14 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6182409347808395 2.474276144822955 0.0133506458526111 0.9999999903267204 0.4264314688127621 28 P09601,P13674,Q8NB78,Q16850,Q14534,P30519,Q9BU89,Q6UW02,Q12797,O75845,P16435,Q15800 12 +Protein carrier chaperone 0.7016545423163083 2.457482065275018 0.0139914796687143 0.9999999960357878 0.4264314688127621 14 Q15070,Q8N4V1,P62072,Q9NPA0 4 +Serine type carboxypeptidase activity 0.91785364827977 2.450047760745011 0.014283726687754 0.9999999973612698 0.4264314688127621 5 P42785,Q9H3G5,P10619 3 +Cholesterol binding 0.707232636079393 2.419801618287611 0.015528976348994 0.9999999995348064 0.4264314688127621 13 O95772,Q14108,O15118,P35610,P45880,P21796 6 +Exopeptidase activity 0.60424478122197 2.4173322582154873 0.0156347383375026 0.999999999598606 0.4264314688127621 34 Q9H3G5,Q969V3,O75844,P42785,Q9HB40,Q7Z2K6,P10619,P55786,Q9NZ08,O14773 10 +Phosphatidylcholine binding 0.8410492922897659 2.4164935081471635 0.0156708056728092 0.9999999996182996 0.4264314688127621 7 P45880,P21796 2 +Sulfur compound transmembrane transporter activity 0.838460092887835 2.4048881029377704 0.016177418371202 0.9999999998117444 0.4264314688127621 7 O00400,Q70HW3,Q9UBX3 3 +Active ion transmembrane transporter activity 0.5907440494980162 2.4029422306680277 0.0162637564691381 0.999999999833115 0.4264314688127621 41 P98194,P21281,P05141,P51798,Q00325,O00400,P05023,Q9Y6M7,P20020,Q9H2J7,Q7KZN9,Q9UDW1,P08195,P13073,P16615,O14548,Q9HD20,P12236,P12235,Q96ES6,P51790 21 +Serine type exopeptidase activity 0.8343695398922296 2.386520508516484 0.0170086586730693 0.9999999999410168 0.4264314688127621 7 P42785,Q9H3G5,P10619,Q9HB40 4 +Anion channel activity 0.7126517952740564 2.3853306894038755 0.0170637749461961 0.9999999999453874 0.4264314688127621 12 P51798,Q4KMQ2,Q9NW15,Q9Y277,Q9Y696,Q9C0H2,P45880,P21796,P51790 9 +Gated channel activity 0.6889285287126493 2.3847438934496967 0.0170910148901939 0.9999999999474264 0.4264314688127621 14 P51798,Q96ER9,Q4KMQ2,Q9NW15,Q9Y277,P21796,Q9Y696,Q9C0H2,P45880,Q9BVC6,P51790 11 +Proton transmembrane transporter activity 0.5941499994414676 2.3742898499973895 0.0175827419081604 0.9999999999735524 0.4264314688127621 37 Q13423,P21281,P24539,O00400,P51790,Q7KZN9,Q9UDW1,P12235,Q93050,O75964,Q96ES6,P13073,O14548,P00846,O75947,P05141,P56385,Q9Y487 18 +Antiporter activity 0.7182854150684603 2.3558643014028564 0.0184796669827462 0.9999999999924536 0.4264314688127621 11 P51798,P12236,Q9UBX3,P12235,P08195,P16260,P05141,P51790 8 +Sphingolipid binding 0.8557056296247226 2.35567645405481 0.0184890135699551 0.9999999999925516 0.4264314688127621 6 P45880,P07602,P21796 3 +Carbohydrate derivative transmembrane transporter activity 0.7422851942665778 2.336640111288066 0.0194579049626013 0.9999999999980806 0.4264314688127621 10 P12236,O00400,Q8TB61,P12235,Q6NUK1,L0R6Q1,P33897,P05141 8 +Fad binding 0.7143241574772716 2.3345531709665095 0.0195667753351813 0.999999999998352 0.4264314688127621 11 Q14534,Q15067,O15254,O95831,Q15392 5 +Organic anion transmembrane transporter activity 0.5936630983801932 2.3160846934835697 0.0205536448710668 0.9999999999995866 0.4341562216611497 31 P12236,Q96NB2,P30825,Q9UBX3,O00400,Q8TB61,Q9H2D1,Q9BQT8,Q9Y619,P12235,Q9HC21,Q6NUK1,P11166,Q9Y6M7,P53985,P05141,O43808 17 +Passive transmembrane transporter activity 0.5783275531288925 2.2543933992171734 0.0241714301809017 0.9999999999999974 0.4625291873275969 37 Q99797,Q4KMQ2,P00846,P21796,P51798,Q9NW15,Q9Y277,O96008,O75964,Q9C0H2,P45880,Q9NVV0,Q96ER9,P24539,Q9Y696,P56385,O75947,Q9BVC6,P51790 19 +Voltage gated channel activity 0.7248125722685393 2.246329851967919 0.0246828878271365 0.9999999999999988 0.4625291873275969 10 P51798,Q4KMQ2,Q9Y277,P21796,Q9Y696,P45880,Q9BVC6,P51790 8 +Monooxygenase activity 0.7242976683673731 2.2436538849892287 0.0248546793541359 0.999999999999999 0.4625291873275969 10 Q16850,Q14534,P30519,Q6UW02,Q9BU89,Q15800 6 +Palmitoyl protein hydrolase activity 0.801164372520204 2.2359303383681284 0.0253563346506797 0.9999999999999996 0.4625291873275969 7 Q9UMR5,P50897 2 +Threonine type peptidase activity 0.7730992528416881 2.2343491680868612 0.0254601075386344 0.9999999999999996 0.4625291873275969 8 P49721,P28070,P20618,P28074,P28072 5 +Threonine type endopeptidase activity 0.7730992528416881 2.2343491680868612 0.0254601075386344 0.9999999999999996 0.4625291873275969 8 P49721,P28070,P20618,P28074,P28072 5 +O acyltransferase activity 0.6470533878004247 2.2100361389359517 0.0271026542829748 1.0 0.4625291873275969 15 Q96N66,P23786,Q8NF37,Q8NCC3,P35610,Q9NUQ2,P50416,Q6P1A2,O15228 9 +Amide binding 0.417901147115041 2.194596461464658 0.028192557609846 1.0 0.4625291873275969 103 Q9Y287,P42892,Q03518,Q9H3P7,Q9UHB9,Q9NZ08,P62942,P24390,P21796,Q15392,Q9NQX7,Q9Y680,Q9Y584,O43731,Q8WTV0,P45880,P00374,P07602,O14773,P55786,Q9UIQ6,Q9H7Z7,Q9NZJ7,O00264 24 +Metallopeptidase activity 0.5598950863463814 2.1912628014838313 0.0284327802833719 1.0 0.4625291873275969 43 O43847,P42892,Q10713,P09960,Q969V3,O75844,Q7Z2K6,P22695,P55786,Q9NZ08,Q9UIQ6 11 +Acylglycerol o acyltransferase activity 0.7136176665499495 2.187960819802861 0.028672456402206 1.0 0.4625291873275969 10 Q96N66,Q8NF37,Q8NCC3,Q9NUQ2 4 +Purine nucleotide transmembrane transporter activity 0.7373012363769781 2.179576893786621 0.029288839114927 1.0 0.4625291873275969 9 P12236,O00400,Q8TB61,P12235,Q6NUK1,P33897,P05141 7 +Metalloexopeptidase activity 0.5755775740418282 2.164007366895576 0.0304637840201882 1.0 0.4647419495524271 22 Q969V3,O75844,Q7Z2K6,P55786,Q9NZ08,Q9UIQ6 6 +Hydrolase activity hydrolyzing o glycosyl compounds 0.586021517240608 2.1454022663965393 0.031920698056385 1.0 0.4704113010446956 19 Q9BTY2,P04062,P04066,O60502,P54802,Q9NUJ1,P06865,P06280 8 +Amyloid beta binding 0.7022493686687817 2.128282287954556 0.0333136857341893 1.0 0.4704113010446956 10 Q9Y287,Q8WTV0,O00264 3 +Lipid binding 0.4358137716393192 2.1093425103943653 0.0349150279320096 1.0 0.4704113010446956 135 O95772,O15118,P04062,Q9Y4G8,P35610,P30536,P21796,O14964,A6NIH7,P50897,Q96L92,O75208,P05023,Q8NCC3,P09455,Q9BQE5,Q8WTV0,Q9H4A6,P45880,Q9NQZ5,P07602,P28070,Q15067,O15173,O15254,Q8NFH5,O14773,Q9Y2I1,O43292,Q14108,P38435,Q9NZJ7,Q96S38,Q9H490,O00264 35 +Voltage gated anion channel activity 0.7734204793028112 2.108067439367006 0.035025156414747 1.0 0.4704113010446956 7 P51798,Q4KMQ2,Q9Y277,P45880,P21796,P51790 6 +Cargo receptor activity 0.7732194254612289 2.1071340780886545 0.0351059591357982 1.0 0.4704113010446956 7 O15260,Q14108,Q8WTV0 3 +Quaternary ammonium group binding 0.6673668326027805 2.0777882267821663 0.0377288686681114 1.0 0.4704113010446956 11 P45880,P21796,Q14108 3 +Serine hydrolase activity 0.5573042901973974 2.037228327384915 0.0416271663773093 1.0 0.4768739941981646 21 Q9H3G5,P42785,Q9HB40,P67812,P10619,O14773,Q16740 7 +Ceramide binding 0.8893034825870629 2.0366470715186655 0.0416854220891673 1.0 0.4768739941981646 4 P45880,P07602,P21796 3 +Acid phosphatase activity 0.8872903175370767 2.0286264398332965 0.0424963534478544 1.0 0.4768739941981646 4 Q9NPH0 1 +Hydrolase activity acting on glycosyl bonds 0.5549885640186455 2.016360862027584 0.0437622549553906 1.0 0.4768739941981646 26 Q9BTY2,P04062,P04066,O60502,O75503,P54802,Q9NUJ1,P06865,P06280 9 +Vitamin transmembrane transporter activity 0.7780192518702087 2.0125729111543267 0.0441595791435192 1.0 0.4768739941981646 6 P11166,Q9H2D1,P04062,P38435 4 +Sterol transporter activity 0.7271459036380502 2.012067360099674 0.0442128367983734 1.0 0.4768739941981646 8 Q9H2C2,O15118 2 +Symporter activity 0.679910741634743 2.0098258125007797 0.0444496278223516 1.0 0.4768739941981646 10 Q9H2J7,Q96ES6,Q9Y6M7,O00400 4 +Peptidase activity 0.4134698132962203 2.002309154378044 0.045251492059043 1.0 0.4768739941981646 116 P42892,Q969V3,P28074,P10619,Q9BXS4,Q9NZ08,O43847,P49721,O75844,Q2T9J0,Q10713,Q9H3G5,P09960,P42785,P28070,P20618,P55786,O14773,O43292,Q16740,Q9UIQ6,Q9BT78,Q9HB40,Q7Z2K6,P67812,P22695 26 +Transition metal ion transmembrane transporter activity 0.8802860696517392 2.000672791761952 0.0454276634028256 1.0 0.4768739941981646 4 Q8N4V1,Q9HD20,Q9HC07 3 +Amide transmembrane transporter activity 0.7721382065805034 1.9860626527162355 0.0470263675581785 1.0 0.4768739941981646 6 O00400,Q9H2D1 2 +Amino acid transmembrane transporter activity 0.6304400064453204 1.9801939384066631 0.0476817407286429 1.0 0.4768739941981646 13 Q96H78,Q9H2J7,Q9Y619,P30825 4 +Wide pore channel activity 0.86691542288557 1.9471061963359984 0.0515220043018735 1.0 0.4768739941981646 4 Q9Y277,P21796,P45880 3 +Porin activity 0.86691542288557 1.9471061963359984 0.0515220043018735 1.0 0.4768739941981646 4 Q9Y277,P21796,P45880 3 +Hexosaminidase activity 0.7970001820047552 1.9420425556756349 0.0521319487403688 1.0 0.4768739941981646 5 P54802,O60502,P06865 3 +Quinone binding 0.7597118335172044 1.9298048347209853 0.0536310242332951 1.0 0.4768739941981646 6 O75306,Q16134,O75251,Q8N0U8 4 +Metal ion transmembrane transporter activity 0.5409518216812103 1.914379965872 0.0555716235045202 1.0 0.4768739941981646 24 Q8N4V1,Q9NVV0,P98194,Q96ER9,Q9HC07,Q9H2J7,P05023,P08195,P16615,Q9Y6M7,Q9HD20,P20020 12 +Snap receptor activity 0.5631750260617849 1.9057934401228231 0.0566770103698686 1.0 0.4783781751980765 18 O95249,O43752,Q9P2W9,O60499 4 +L amino acid transmembrane transporter activity 0.6799229320555424 1.8872985379733156 0.0591201829902068 1.0 0.4783781751980765 9 P30825 1 +Scavenger receptor activity 0.8518027293734345 1.886243816536558 0.0592621064644292 1.0 0.4783781751980765 4 Q14108,Q8WTV0 2 +G protein alpha subunit binding 0.850267942197836 1.8800444779706624 0.0601020164007652 1.0 0.4783781751980765 4 P80303 1 +Atp transmembrane transporter activity 0.7825816485225504 1.879572089569598 0.0601664200701725 1.0 0.4783781751980765 5 P05141,P12236,P12235,Q6NUK1 4 +Solute cation symporter activity 0.7002472899258805 1.87938310411913 0.0601922016599592 1.0 0.4783781751980765 8 Q9H2J7,Q96ES6,Q9Y6M7,O00400 4 +Phospholipid binding 0.3790007124493111 1.8746905193211263 0.0608353119318474 1.0 0.4783781751980765 85 Q9H4A6,P07602,Q14108,Q9NZJ7,Q8NCC3,Q9Y4G8,Q8NFH5,Q8WTV0,O14773,Q9Y2I1,Q96S38,P45880,O43292,P21796,Q9H490,O14964,P50897 17 +Atpase coupled transmembrane transporter activity 0.5309220945139551 1.8429977413553944 0.0653293402575505 1.0 0.4895533449499986 23 P51798,P98194,P21281,Q03518,P08183,O75027,P16615,Q9HD20 8 +Oxidoreductase activity acting on the ch ch group of donors 0.5309890031273559 1.8413956619031848 0.0655635980723816 1.0 0.4895533449499986 28 Q9H7Z7,Q15067,Q7KZN9,O15254,Q8N4Q0,Q14914,P49748,Q9NZ01,Q6NUM9,Q14739,Q15392,Q99643 12 +Flavin adenine dinucleotide binding 0.5284552261724028 1.822382532287496 0.0683969631301666 1.0 0.499516119030419 28 A1L0T0,Q15067,O15254,P49748,O95831,Q16134,P16435,Q15392 8 +Peptide antigen binding 0.7623152563286089 1.791135007307444 0.0732716326415132 1.0 0.5212536353201954 5 Q03518,Q15392,P10321 3 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8274569852373593 1.7875201356252952 0.0738534606611294 1.0 0.5226845437511891 4 Q15800,Q16850 2 +Carboxypeptidase activity 0.6052916851073471 1.7767869202197564 0.0756033047130766 1.0 0.5242508606778394 12 P42785,Q9H3G5,P10619 3 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.7565400316709998 1.7658029490410443 0.0774289135928871 1.0 0.528904966980269 5 Q9UHG3 1 +Lamin binding 0.6725446382934078 1.7408108832120814 0.081716733654406 1.0 0.5426418626427562 8 P42167,Q5SNT2,Q9ULX6,Q9UH99,Q14739 5 +G protein coupled receptor activity 0.8158740995138561 1.7402720235142168 0.0818112640692283 1.0 0.5426418626427562 4 Q99720 1 +Mannose binding 0.7443698455834923 1.7122379054764938 0.0868528346068071 1.0 0.5557013416859544 5 O75503,P35613,Q12907 3 +Antigen binding 0.6888735435361751 1.7072149017976397 0.0877821162468683 1.0 0.5578190397190617 7 Q03518,Q15392,P10321 3 +Arachidonate coa ligase activity 0.7093432555110356 1.698514297288428 0.0894107365626508 1.0 0.5578190397190617 6 Q9UKU0 1 +Long chain fatty acid coa ligase activity 0.7093432555110356 1.698514297288428 0.0894107365626508 1.0 0.5578190397190617 6 Q9UKU0 1 +Proton channel activity 0.5978025563207582 1.6834781266683054 0.0922825702532803 1.0 0.5578190397190617 11 O75964,P56385,P00846,P24539 4 +Proton transporting atp synthase activity rotational mechanism 0.5978025563207582 1.6834781266683054 0.0922825702532803 1.0 0.5578190397190617 11 O75964,P56385,P00846,P24539 4 +Iron ion binding 0.5079031564696354 1.681486531885524 0.0926684502959611 1.0 0.5578190397190617 21 P13674,Q16850,P31350,Q9BU89,Q6UW02,O75845,Q9BV57,Q15800 8 +Exogenous protein binding 0.5707381192342011 1.6790392269248249 0.0931443990136338 1.0 0.5578190397190617 14 P11279,Q14108,Q8WTV0,O15118 4 +Lysophospholipid acyltransferase activity 0.6593408703237588 1.6741062473109585 0.0941097201991265 1.0 0.5578190397190617 8 Q96N66,Q8NF37,Q9NUQ2 3 +Primary active transmembrane transporter activity 0.4722597877824091 1.6720105786419492 0.0945222360804241 1.0 0.5578190397190617 55 O75306,O43676,P51798,P98194,P21281,P03886,Q03518,Q7KZN9,Q9UDW1,P08183,O75027,P13073,P16615,Q9Y6M9,Q9HD20 15 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.5785944023873562 1.6710054125942273 0.0947206087163601 1.0 0.5578190397190617 13 Q9H7Z7,Q8N4Q0,Q14914,Q9NZ01,Q14739,Q15392 6 +Endopeptidase activity 0.4473744102550799 1.662345337614354 0.0964435522423845 1.0 0.5578190397190617 63 Q4J6C6,Q99797,P42892,P28074,Q9BXS4,Q9NZ08,O43847,Q96K76,P49721,O75844,Q2T9J0,Q10713,P28070,P20618,P28072,O14773,O43292,Q16740,P67812,Q99436,P22695 21 +Signal recognition particle binding 0.7282321686026876 1.6408444383242908 0.100829711023447 1.0 0.5646219641947908 5 Q9BUN8 1 +Dicarboxylic acid transmembrane transporter activity 0.6527084485825808 1.6404462616373616 0.1009124131999805 1.0 0.5646219641947908 8 Q9UBX3 1 +P type transmembrane transporter activity 0.7251798419582504 1.6272960064751878 0.1036742456701391 1.0 0.5683272420208361 5 P05023,P98194,P16615 3 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.7869859680338389 1.6217175777102042 0.1048638333590346 1.0 0.5683272420208361 4 Q7KZN9 1 +Protein lipid complex binding 0.7833092456541624 1.606560944021736 0.1081507158378425 1.0 0.5683272420208361 4 Q9BQE5 1 +Adp transmembrane transporter activity 0.782338308457709 1.6025560598200652 0.1090327013698551 1.0 0.5683272420208361 4 P05141,P12236,P12235 3 +Organic cation transmembrane transporter activity 0.7823383084577077 1.6025560598200592 0.1090327013698564 1.0 0.5683272420208361 4 Q9HC21,O43772,Q70HW3 3 +Acetylgalactosaminyltransferase activity 0.7819694196187692 1.6010342252601455 0.1093693389064629 1.0 0.5683272420208361 4 Q8N4A0 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.7819694196187692 1.6010342252601455 0.1093693389064629 1.0 0.5683272420208361 4 Q8N4A0 1 +Beta n acetylhexosaminidase activity 0.781230166803411 1.5979840482529215 0.1100465272350275 1.0 0.5683272420208361 4 O60502,P06865 2 +Mhc protein binding 0.6042278832539056 1.5971259293371067 0.1102376393815434 1.0 0.5683272420208361 10 Q9BUN8,Q9NUQ9 2 +Solute proton symporter activity 0.7806626672411459 1.5956421491949502 0.1105687114395381 1.0 0.5683272420208361 4 O00400 1 +Oxidoreductase activity acting on a heme group of donors 0.6633217348317266 1.5829725529565564 0.1134277204102875 1.0 0.5746725465805346 7 Q7KZN9,P13073,O14548,P20674,P16435 5 +Molecular transducer activity 0.4946614137945482 1.5707913887357745 0.1162311129505559 1.0 0.5819001093428475 32 Q14108,O15118,Q6RW13,Q9BUN8,Q99442,O15173,Q99523,P30536,Q8WTV0,Q15629,P10586,Q99720 12 +Sulfotransferase activity 0.9045694746658356 1.552265735034885 0.1205986530694445 1.0 0.5934836941374456 3 Q8NCH0,Q7LGA3 2 +Histone methyltransferase activity 0.5405846112152654 1.547749684640216 0.1216825747979939 1.0 0.5966791971344488 15 Q03164,O96028,Q9BV86 3 +Mhc class ib protein binding 0.9001130527696928 1.5355876367557486 0.1246395482905708 1.0 0.6068443255423895 3 Q9NUQ9 1 +Atpase coupled cation transmembrane transporter activity 0.5400077454368903 1.4870108638435156 0.1370119416809683 1.0 0.6500179231289324 14 Q9HD20,P98194,P21281,P16615 4 +Cdp alcohol phosphatidyltransferase activity 0.753731343283579 1.484154946301279 0.1377678191045297 1.0 0.6500179231289324 4 O14735,Q9BVG9,Q9C0D9 3 +Sodium ion transmembrane transporter activity 0.6412928847602826 1.4748632825998549 0.1402493035217076 1.0 0.6540315309012804 7 Q9H2J7,P05023,P08195,Q9Y6M7,P55011 5 +Tap binding 0.7506939086221521 1.4715422962283289 0.1411445177702199 1.0 0.6540315309012804 4 Q03518,P10321 2 +Potassium ion transmembrane transporter activity 0.6902021772939226 1.4711217591951815 0.1412581914894728 1.0 0.6540315309012804 5 P05023,Q9NVV0,P55011,Q96ER9 4 +Long chain acyl coa dehydrogenase activity 0.7505855059366255 1.4710920373769376 0.1412662281391652 1.0 0.6540315309012804 4 P49748,Q9NZ01 2 +Hormone binding 0.6396142278709167 1.4665907219281196 0.1424874254762327 1.0 0.6564940777814346 7 O43847,P42892,P30536 3 +Manganese ion transmembrane transporter activity 0.880012433944661 1.4602654839139666 0.1442171243100474 1.0 0.659425209219718 3 Q9HD20,Q9HC07 2 +Abc type transporter activity 0.615356525943004 1.449112237591693 0.1473062410241064 1.0 0.6697068507486691 8 O75027,Q9HD20,P08183 3 +Steroid dehydrogenase activity 0.6352538407594689 1.445081221400635 0.1484350729640096 1.0 0.6703991946696881 7 Q3SXM5 1 +Protein methyltransferase activity 0.4719933578856253 1.4097887759454102 0.1586020618017689 1.0 0.6979622128409116 22 Q03164,O96028,O60725,Q9BV86,O15047 5 +Thiolester hydrolase activity 0.4898596142215764 1.4008000039194206 0.1612738874814197 1.0 0.6979622128409116 18 Q9UMR5,P50897 2 +Nadh dehydrogenase activity 0.4662980749224079 1.3571484762925463 0.1747340381288449 1.0 0.709292191108458 24 O75306,O43676,O95831,P03886 4 +Oxidoreductase activity acting on nad p h 0.4673390079117768 1.3528173364071412 0.1761139928982904 1.0 0.709292191108458 31 O75306,O43676,Q13423,P03886,Q7KZN9,O95831,Q9Y6M9 7 +Glycosphingolipid binding 0.8502398033914156 1.34853654991335 0.1774858727136314 1.0 0.709292191108458 3 P07602 1 +Er retention sequence binding 0.9841516469857045 1.3471589276506368 0.1779290528175372 1.0 0.709292191108458 2 P24390 1 +Udp glycosyltransferase activity 0.462779991680298 1.3462338913764422 0.178227098275614 1.0 0.709292191108458 21 Q8N4A0,Q16739,Q8NBI6,O43505,Q10472,P13807,P06865 7 +Glucosidase activity 0.6614038409892299 1.3414908294297516 0.1797611451944898 1.0 0.710773481097543 5 P04062 1 +Signal sequence binding 0.4650127201355686 1.334530898911055 0.1820299273619727 1.0 0.710773481097543 29 Q9Y584,P24390,O43731 3 +Acyl coa binding 0.5353344655538179 1.3165791697149267 0.187979724847664 1.0 0.7230316739430594 11 P35610,P49748,Q9H3P7 3 +Fatty acid derivative binding 0.5353344655538179 1.3165791697149267 0.187979724847664 1.0 0.7230316739430594 11 P35610,P49748,Q9H3P7 3 +Heme transmembrane transporter activity 0.9751398384089496 1.313607909034288 0.1889781857746393 1.0 0.7230316739430594 2 O15173 1 +Proline rich region binding 0.6272200828385414 1.3118676121974744 0.189564807092974 1.0 0.7230316739430594 6 Q9UQB8,Q9UI14 2 +Acetylglucosaminyltransferase activity 0.6447411682454669 1.2661934868526474 0.2054438187778371 1.0 0.7345686541197145 5 O43505,P06865 2 +Palmitoyltransferase activity 0.6410293083027163 1.249401209499558 0.2115183662766018 1.0 0.7446531202507033 5 P23786,O15269 2 +L ornithine transmembrane transporter activity 0.9561839651957708 1.2432177959520183 0.2137875866245759 1.0 0.7472166345143325 2 P30825 1 +Lipid transporter activity 0.4468912366732804 1.2335159087646876 0.2173833450345641 1.0 0.7472166345143325 20 O15118,O14975,Q9H2C2,P08183,P11166,P30536,P17900,P33897 8 +Ephrin receptor binding 0.6095550800449147 1.2276383312789476 0.2195827658243012 1.0 0.7472166345143325 6 P46108,O00560,P62993 3 +Oxidoreduction driven active transmembrane transporter activity 0.4498651839805488 1.213609177250368 0.2248970009096247 1.0 0.7472166345143325 32 O75306,O43676,P03886,Q7KZN9,Q9UDW1,P13073 6 +High density lipoprotein particle binding 0.8139805628771543 1.21258627685366 0.2252880382353006 1.0 0.7472166345143325 3 Q9BQE5 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.6324297608193188 1.2104812918697023 0.2260942651953179 1.0 0.7472166345143325 5 Q96N66,Q8NF37 2 +Single stranded dna exodeoxyribonuclease activity 0.6319302014502132 1.2082199032348069 0.2269626879631543 1.0 0.7472166345143325 5 Q8IV08 1 +Phospholipase a1 activity 0.946239900559348 1.206417474561948 0.2276565615540033 1.0 0.7472166345143325 2 Q8NCC3 1 +Cytokine activity 0.6050548065237111 1.2061501885763242 0.2277595861236392 1.0 0.7472166345143325 6 P43490 1 +Electron transfer activity 0.4235810529169133 1.205451719683914 0.2280289656675203 1.0 0.7472166345143325 55 O75306,O43676,P03886,Q16134,Q7KZN9,Q9UDW1,P13073,O43175,Q9Y6M9,Q9Y6N1,P14406,Q99643 12 +Molecular carrier activity 0.4470658643431086 1.2027381567126931 0.2290776632495452 1.0 0.7475713529004274 37 Q53FT3,Q8N4V1,Q9NPA0,P62072,Q15070 5 +Proteasome binding 0.5157324978401598 1.1995474746232258 0.2303151363997675 1.0 0.7475713529004274 11 P46379,O76024 2 +Phosphatidylserine binding 0.532826952296447 1.194094372470658 0.2324410543179502 1.0 0.7503278463964602 10 Q8WTV0 1 +Nadp retinol dehydrogenase activity 0.6276266974786053 1.188737806497179 0.2345428584636053 1.0 0.7503278463964602 5 Q8NBN7,Q9HBH5 2 +Cation channel activity 0.4425915224410977 1.1869478974335703 0.2352481727338096 1.0 0.7503278463964602 22 Q96ER9,P24539,Q4KMQ2,Q9NW15,O75964,P00846,O75947,P56385 8 +Lysophospholipase activity 0.5620994019703882 1.1722110664179477 0.2411123264834616 1.0 0.7503278463964602 8 Q8NCC3 1 +Sulfatide binding 0.9334990677439324 1.1594253671768893 0.2462828416852855 1.0 0.7503278463964602 2 P50897 1 +Lysophosphatidic acid binding 0.9334990677439324 1.1594253671768893 0.2462828416852855 1.0 0.7503278463964602 2 P50897 1 +Solute anion antiporter activity 0.6211397601548414 1.1593704852571491 0.246305202069589 1.0 0.7503278463964602 5 P12236,P12235 2 +Voltage gated chloride channel activity 0.7988809449797856 1.1561538317969422 0.2476182402941669 1.0 0.7503278463964602 3 P51798,P51790 2 +Protein prenyltransferase activity 0.6748797441550268 1.1555021513476145 0.2478848521330414 1.0 0.7503278463964602 4 P49356,P49354 2 +Phospholipase a2 activity 0.7982514955983002 1.153805046563681 0.248580104731432 1.0 0.7503278463964602 3 Q8NCC3 1 +Calcium independent phospholipase a2 activity 0.7982514955983002 1.153805046563681 0.248580104731432 1.0 0.7503278463964602 3 Q8NCC3 1 +Vitamin d binding 0.9288377874456146 1.142283908289018 0.2533360278045471 1.0 0.7503278463964602 2 P04062 1 +Nadph binding 0.67014526673956 1.1357731950563748 0.2560514981055908 1.0 0.7507401338074775 4 Q14739 1 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.7917314267951476 1.1294958477378108 0.2586887201888834 1.0 0.7555829133382733 3 O95864,O75845 2 +Ion gated channel activity 0.7886229406278847 1.1179203076172135 0.2636010309461274 1.0 0.7555829133382733 3 Q4KMQ2,Q9C0H2 2 +Intracellular calcium activated chloride channel activity 0.7886229406278847 1.1179203076172135 0.2636010309461274 1.0 0.7555829133382733 3 Q4KMQ2,Q9C0H2 2 +Solute sodium symporter activity 0.6655156762766228 1.1164942501014594 0.2642106300596667 1.0 0.7557524897331717 4 Q9Y6M7 1 +Camp binding 0.786538171240191 1.110162410942758 0.2669290472674275 1.0 0.7603601284194563 3 Q9Y4G8 1 +P type calcium transporter activity 0.7824059682934262 1.0947993169510972 0.2736045657577444 1.0 0.7733949427446114 3 P98194,P16615 2 +Gpi anchor binding 0.7802300279763618 1.086717135220494 0.277161838836284 1.0 0.7793100735820452 3 O43292,Q9H490 2 +Lipopolysaccharide binding 0.5604432681541862 1.072729812243001 0.2833923602719554 1.0 0.7793100735820452 7 Q8WTV0 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.6549367624725428 1.072501548851872 0.2834948186486472 1.0 0.7793100735820452 4 Q10713 1 +Phosphoric diester hydrolase activity 0.5271106282448711 1.0691280984355187 0.2850119520082901 1.0 0.7810806588969708 9 Q8IV08 1 +Hexosyltransferase activity 0.4304510660336709 1.0637840396660836 0.2874265431435705 1.0 0.784244164741601 37 Q8N4A0,P04062,Q16739,P46977,Q13126,O75340,O43505,Q10472,Q9BV10,P13807,P06865,Q9BT22 12 +Solute cation antiporter activity 0.7715262667081147 1.0544466023277876 0.2916784956794611 1.0 0.784244164741601 3 P08195,P51790 2 +Mhc class i protein binding 0.52411877806099 1.052767094468 0.2924477495560875 1.0 0.784244164741601 9 Q9BUN8,Q03518 2 +Phospholipase binding 0.6493127405744086 1.0491564909565223 0.2941060998267009 1.0 0.784244164741601 4 P07196,P84103 2 +Phosphotransferase activity for other substituted phosphate groups 0.5372171788847746 1.0419962210739098 0.2974134309657419 1.0 0.784244164741601 8 Q9BVG9,P48651,O14735,Q9NRN7,Q9C0D9 5 +Mitochondrion targeting sequence binding 0.7659309916070545 1.033755076121906 0.3012506781083011 1.0 0.784244164741601 3 Q9Y584,Q15388 2 +Ganglioside binding 0.8887507768800373 0.9963189388965908 0.3190952046542223 1.0 0.8009464643331761 2 P07602 1 +Dioxygenase activity 0.4530522490373451 0.97551445932167 0.3293051328731737 1.0 0.8027867893354093 15 Q9BV57,P16435,Q12797 3 +Fk506 binding 0.5397761012977222 0.9695732930933926 0.3322592304656364 1.0 0.8027867893354093 7 P62942,Q9Y680,Q96AY3,P26885 4 +Macrolide binding 0.5397761012977222 0.9695732930933926 0.3322592304656364 1.0 0.8027867893354093 7 P62942,Q9Y680,Q96AY3,P26885 4 +Structural constituent of eye lens 0.7479017718370977 0.9674204378484448 0.3333338971239157 1.0 0.8027867893354093 3 Q99797,P08670 2 +Lipid transfer activity 0.5548585608730878 0.966511004589766 0.3337885430378908 1.0 0.8027867893354093 6 P30536,P48739,P61916,Q9BZF1 4 +Transferase activity transferring sulphur containing groups 0.4768910260948363 0.9663659909587816 0.3338610755357019 1.0 0.8027867893354093 11 Q5VV42,Q8NCH0,Q7LGA3,Q9NRB3 4 +Phosphatidyl phospholipase b activity 0.7416827558658421 0.9446765814363698 0.3448240164711342 1.0 0.813476588685339 3 Q8NCC3 1 +Phosphatidylinositol phosphate phosphatase activity 0.547471640818346 0.9313953515323646 0.3516490945458796 1.0 0.8222138691809343 6 Q10713 1 +Metalloaminopeptidase activity 0.4588401707601661 0.9274265755921428 0.3537050977543501 1.0 0.8222138691809343 13 Q9NZ08,Q9UIQ6,P55786 3 +Diacylglycerol binding 0.8632691112492232 0.9053118901223004 0.3653001790808792 1.0 0.8277881466421223 2 Q9Y4G8 1 +Pre mrna intronic binding 0.561346219312026 0.8899549827815412 0.3734900587702732 1.0 0.8389776934928244 5 P22626,Q9BWF3 2 +Aspartic type peptidase activity 0.7257519309967078 0.8867984864947286 0.3751874026253416 1.0 0.8389776934928244 3 Q92542 1 +Ribosomal protein s6 kinase activity 0.8564325668116795 0.8811951047550342 0.3782122283909155 1.0 0.8402676206807881 2 Q15418 1 +Nadplus binding 0.5579700578674361 0.874895655395696 0.3816306832391261 1.0 0.843766389834654 5 Q8IXJ6,Q16836 2 +G protein beta gamma subunit complex binding 0.6032323159241766 0.859721681311466 0.3899424802820495 1.0 0.8471330949379342 4 P41208 1 +Triglyceride lipase activity 0.7169213117878781 0.8549851466858451 0.3925593706702051 1.0 0.8471330949379342 3 Q8NCG7 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.7120332530067897 0.8374676591708384 0.4023297483598984 1.0 0.8507727668739823 3 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.7120332530067897 0.8374676591708384 0.4023297483598984 1.0 0.8507727668739823 3 Q10713 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.7120332530067897 0.8374676591708384 0.4023297483598984 1.0 0.8507727668739823 3 Q10713 1 +Poly a binding 0.4498661409915112 0.8358400451835933 0.4032448948856924 1.0 0.8507727668739823 12 Q93062,O14979 2 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.7098950853012693 0.8298269544162233 0.4066366287454745 1.0 0.852610088388104 3 Q99757 1 +Volume sensitive anion channel activity 0.8415164698570345 0.8290866682633169 0.407055367046065 1.0 0.852610088388104 2 Q9C0H2 1 +Peptide receptor activity 0.8387197016780414 0.8194001077500596 0.4125581734822328 1.0 0.8556574588674463 2 Q99720 1 +Sphingosine n acyltransferase activity 0.8371659415786044 0.8140307687454899 0.4156273245689685 1.0 0.8556574588674463 2 Q96G23 1 +Quaternary ammonium group transmembrane transporter activity 0.8362336855189572 0.8108133710998522 0.4174728546427388 1.0 0.8556574588674463 2 O43772 1 +Azole transmembrane transporter activity 0.8362336855189365 0.8108133710997818 0.4174728546427793 1.0 0.8556574588674463 2 P30825 1 +Protease binding 0.3966763800558554 0.8074242033530505 0.4194221272186647 1.0 0.8556574588674463 26 P07602,Q9NZJ7,Q9BUN8,Q2T9J0,P46379,Q13438,P54725 7 +Peptidyl proline dioxygenase activity 0.5893097234734851 0.8034475639727849 0.4217160928126828 1.0 0.8556574588674463 4 P13674 1 +Procollagen proline dioxygenase activity 0.5893097234734851 0.8034475639727849 0.4217160928126828 1.0 0.8556574588674463 4 P13674 1 +Glucose binding 0.5200189851542792 0.8017864488447796 0.4226764987021516 1.0 0.8556574588674463 6 P52789 1 +Translation repressor activity 0.4772270085173283 0.7972302214987063 0.4253173372302063 1.0 0.8556574588674463 9 P00374 1 +Hsp70 protein binding 0.4031674100819241 0.7838667151292985 0.4331183221916532 1.0 0.8618426903900578 18 Q53FT3 1 +Ubiquitin specific protease binding 0.4865688940247344 0.7782454832831386 0.4364243078075769 1.0 0.8634158135732033 8 Q9BUN8 1 +Phosphatidic acid binding 0.6937288106789452 0.7725258319017021 0.43980305335576 1.0 0.8651140290221467 3 Q9Y4G8 1 +5 3 exodeoxyribonuclease activity 0.8238036047234119 0.7682291253245768 0.4423510729349256 1.0 0.8674745858012395 2 Q8IV08 1 +Phospholipase d activity 0.8213175885643065 0.7597856039843264 0.4473827494215476 1.0 0.8674745858012395 2 Q8IV08 1 +Atpase binding 0.3918704060127379 0.7502736223073262 0.4530899258260503 1.0 0.8674745858012395 30 Q9BUN8,Q93050,O76024,Q16740 4 +Mdm2 mdm4 family protein binding 0.5088225456551853 0.7495028532724972 0.4535541795468731 1.0 0.8674745858012395 6 Q96JB5,P61289 2 +Death domain binding 0.5745376651602938 0.7444401944882539 0.4566102097157682 1.0 0.8674745858012395 4 Q07820,Q13546 2 +Cyclic nucleotide binding 0.5242310992509074 0.7261728933359253 0.4677327871260419 1.0 0.8743749226786208 5 Q9Y4G8 1 +Demethylase activity 0.4753253844163712 0.7204706951890486 0.4712352364572421 1.0 0.8748819448954112 8 Q16850 1 +Galactoside binding 0.8095090118085648 0.7200374876052655 0.4715019146569323 1.0 0.8748819448954112 2 P06280 1 +Galactosidase activity 0.8095090118085648 0.7200374876052655 0.4715019146569323 1.0 0.8748819448954112 2 P06280 1 +Pentosyltransferase activity 0.414150956799299 0.7199895662295022 0.4715314196814306 1.0 0.8748819448954112 15 Q8IXJ6,P43490,Q13126 3 +Xenobiotic transmembrane transporter activity 0.676815550252623 0.7135761534049998 0.4754893076081907 1.0 0.879847465425938 3 P08183 1 +Histone methyltransferase activity h3 k4 specific 0.5199611278047299 0.707639768873237 0.4791689897230671 1.0 0.8819021754554572 5 Q03164 1 +Ubiquinone binding 0.8036047234306858 0.7003976227311827 0.4836790204838477 1.0 0.8856257780376523 2 Q16134 1 +Coa hydrolase activity 0.4591176952421261 0.6998083815219969 0.4840469797183564 1.0 0.8856257780376523 9 O14734,P50897 2 +Modified amino acid binding 0.3798514208789594 0.6992155971393682 0.4844173046658973 1.0 0.8856257780376523 23 Q14108,Q8WTV0,P00374 3 +Nadp binding 0.4091473252401583 0.6874573317258933 0.491794579909047 1.0 0.8931666113956636 15 Q13423,Q14739,P16435,P00374 4 +Lysine n methyltransferase activity 0.4557089605903012 0.6816119075896302 0.4954843834815872 1.0 0.8938900927331404 9 Q03164,O96028 2 +Histone lysine n methyltransferase activity 0.4557089605903012 0.6816119075896302 0.4954843834815872 1.0 0.8938900927331404 9 Q03164,O96028 2 +Carnitine o acyltransferase activity 0.7952144188937018 0.6727752050775152 0.5010903143306771 1.0 0.8958294291354423 2 P23786 1 +O palmitoyltransferase activity 0.7952144188937018 0.6727752050775152 0.5010903143306771 1.0 0.8958294291354423 2 P23786 1 +Proteoglycan binding 0.6629034380089709 0.6659756301342816 0.5054266772559957 1.0 0.8969129609112039 3 P10586 1 +Nucleobase transmembrane transporter activity 0.7927284027345993 0.6646581746235886 0.5062691512790845 1.0 0.8969129609112039 2 P12235 1 +Oxidative phosphorylation uncoupler activity 0.7927284027345993 0.6646581746235886 0.5062691512790845 1.0 0.8969129609112039 2 P12235 1 +Myosin v binding 0.5527711499899423 0.6591265885592476 0.5098144830850089 1.0 0.8997111635934668 4 Q15907 1 +Calcium activated cation channel activity 0.7883778744561871 0.650530260376084 0.5153497617590546 1.0 0.9071477216604896 2 Q4KMQ2 1 +3 hydroxyacyl coa dehydratase activity 0.7862026103169648 0.6435037905647816 0.519897255954215 1.0 0.91281193404749 2 Q9P035 1 +Misfolded protein binding 0.417286788812835 0.6383456128691166 0.5232487261529868 1.0 0.9140209936489196 12 Q9BUN8,P46379 2 +Potassium channel activity 0.7806090739589842 0.6255537702098848 0.5316076694683045 1.0 0.920425384842348 2 Q96ER9 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.5422909709322088 0.6188834193484173 0.5359931621814225 1.0 0.9222037740289386 4 O15254 1 +Acetyl coa c acetyltransferase activity 0.4788766753863859 0.6121787484362697 0.5404195004261605 1.0 0.9260920622197962 6 Q9BWD1 1 +Solute proton antiporter activity 0.7712865133623409 0.5960298633300475 0.5511552768400327 1.0 0.927831079712504 2 P51790 1 +Calcium cation antiporter activity 0.7712865133623408 0.5960298633300475 0.5511552768400327 1.0 0.927831079712504 2 P08195 1 +Cation cation antiporter activity 0.7712865133623408 0.5960298633300475 0.5511552768400327 1.0 0.927831079712504 2 P08195 1 +Glycosyltransferase activity 0.3648479149361268 0.5797659476054409 0.5620724640557886 1.0 0.9293218293307094 51 Q8N4A0,Q8IXJ6,P04062,Q13126,O43505,Q10472,Q9BV10,P43490,P06865 9 +Transmembrane transporter binding 0.3665800085339851 0.5507489289979425 0.5818057982102474 1.0 0.9369769780869346 30 P62942,P21796,Q9Y639,P16615 4 +Aspartic endopeptidase activity intramembrane cleaving 0.7554381603480468 0.5470452377878283 0.584347653365789 1.0 0.9369769780869346 2 Q92542 1 +O methyltransferase activity 0.4528857427078525 0.5466648445082365 0.5846090108362674 1.0 0.9369769780869346 7 O60725 1 +Four way junction dna binding 0.4805598755832065 0.5410819332945372 0.5884511103457797 1.0 0.9369769780869346 5 P09429,P26583,P43246,P52701 4 +Primary mirna binding 0.6240960489484952 0.538397980213549 0.5903023204990521 1.0 0.9369769780869346 3 P40763 1 +Phosphoserine residue binding 0.5205223880596943 0.5373945424748827 0.590995112316052 1.0 0.9369934055542024 4 P31946,Q13526,O95104 3 +Small ribosomal subunit rrna binding 0.4791477752973928 0.5352931870981601 0.592447136685563 1.0 0.9382121322598362 5 Q9NVS2,Q14011 2 +Phosphatidylglycerol binding 0.7486016159105031 0.5264160640938622 0.5985991567333317 1.0 0.9398185961267188 2 Q9UJZ1 1 +Cardiolipin binding 0.7486016159105031 0.5264160640938622 0.5985991567333317 1.0 0.9398185961267188 2 Q9UJZ1 1 +Protein arginine n methyltransferase activity 0.4761649994902031 0.5231141447316794 0.6008948228195958 1.0 0.9398185961267188 5 Q6P2P2 1 +C acyltransferase activity 0.4017181744677928 0.5220656642336464 0.6016246120450686 1.0 0.9398185961267188 11 P35610,Q9BWD1 2 +Calcium ion transmembrane transporter activity 0.3930653002510771 0.5210096318693437 0.6023600616107156 1.0 0.9398185961267188 13 P98194,Q9HC07,P08195,P16615,P20020 5 +Armadillo repeat domain binding 0.6174263215955673 0.5173737892856894 0.6048952529429252 1.0 0.9416339935267988 3 Q9P1Z2 1 +Apolipoprotein binding 0.6164940212697705 0.5144585984977021 0.6069313991275671 1.0 0.941790939527119 3 Q8WTV0 1 +C acetyltransferase activity 0.4421460043932091 0.4970212727761011 0.6191740501748124 1.0 0.9498614199888464 7 Q9BWD1 1 +Aminopeptidase activity 0.3784857369993772 0.49162172120199 0.6229867851256956 1.0 0.9513164299829608 15 Q9NZ08,Q9UIQ6,P55786 3 +Acyl coa oxidase activity 0.6084440562256164 0.4895368982962994 0.6244616382300812 1.0 0.9513164299829608 3 O15254 1 +Nucleotidase activity 0.4360576749019859 0.4692938551369906 0.6388596069088344 1.0 0.955823465067566 7 Q969T7,Q9H857 2 +Guanyl nucleotide exchange factor activity 0.3542217382031991 0.4673495952427326 0.6402497786479293 1.0 0.955823465067566 28 P80303,Q02818 2 +Oxidoreductase activity acting on ch or ch2 groups 0.5996576778034326 0.4628668373771616 0.6434598193497858 1.0 0.955823465067566 3 Q7LG56 1 +Neutral amino acid transmembrane transporter activity 0.4605662372701273 0.4605768736821091 0.6451022067305048 1.0 0.955823465067566 5 Q96NB2 1 +Histone acetyltransferase binding 0.4432918098307423 0.4560465245208101 0.6483565229381041 1.0 0.955823465067566 6 P12004,Q8IXJ6,O95905 3 +1 phosphatidylinositol 4 kinase activity 0.7224984462399066 0.4507098771326195 0.6521986626728618 1.0 0.955823465067566 2 P42356 1 +Leukotriene c4 synthase activity 0.7221876942200183 0.4498396461553094 0.6528260685161966 1.0 0.955823465067566 2 O14880 1 +Glucosyltransferase activity 0.4097378857690561 0.4431532510458179 0.6576548902859325 1.0 0.957801095546134 9 P04062,Q16739 2 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3467684125978658 0.4342012027642891 0.6641423397613517 1.0 0.9588974571229352 25 O75306,O43676,P03886 3 +Heparin binding 0.3756147582503101 0.4179935317232991 0.6759518464333603 1.0 0.9723705952378824 13 P10586,Q53GQ0,O14737 3 +Single stranded dna helicase activity 0.3755306304178742 0.39507455571932 0.6927878662436964 1.0 0.9775927444528212 12 P40938,P25205,P49736,Q14566 4 +Oxidoreductase activity 0.3670803256105138 0.3823009129130266 0.7022381776186282 1.0 0.9828471130177132 230 O43676,Q16850,Q99536,P03886,Q8N0U8,P30519,Q3SXM5,Q9BU89,P30837,O43169,Q6NUM9,Q96CU9,Q15392,O75306,Q13423,Q53GQ0,O95139,Q9Y320,P31350,P49748,P51648,Q9NZ01,Q99757,Q12797,O95831,Q9H9P8,Q14739,Q9BV57,Q8NBX0,Q15800,P14406,P00374,P09601,P13674,Q99643,Q96JJ7,Q8NB78,Q14534,Q15067,O95864,Q9UDW1,O15254,Q8NBM8,Q7KZN9,P13073,O14548,O75845,Q9Y6M9,Q9Y6N1,P16435,Q9UBM7,O75251,Q9H7Z7,Q9H3N1,Q9UHG3,Q02252,Q8N4Q0,Q14914,Q6UW02,Q8NBN7,O43175,P78417,Q7LG56,Q16134 64 +Protein geranylgeranyltransferase activity 0.5669445810715913 0.3689867654027706 0.7121375894955955 1.0 0.9846591083383964 3 P49354 1 +P type potassium transmembrane transporter activity 0.6895587321317345 0.3629447712836444 0.7166461411807865 1.0 0.9846591083383964 2 P05023 1 +1 acylglycerophosphocholine o acyltransferase activity 0.4673082127963668 0.3538915767317261 0.7234201398768783 1.0 0.9846591083383964 4 Q8NF37 1 +Mitogen activated protein kinase kinase binding 0.6805469235550108 0.3406075742008206 0.7333990266815718 1.0 0.9872126114056844 2 Q9UL54 1 +Retromer complex binding 0.4139777268907216 0.3359692884383896 0.7368940259710057 1.0 0.9890083066062472 6 Q99523,P20645 2 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.4101695059388708 0.3210893469734708 0.7481426831186415 1.0 0.993846885745042 6 Q15418,P51812 2 +Mutlalpha complex binding 0.5483369599005368 0.3198523454613707 0.7490802643522687 1.0 0.993846885745042 3 P12004,P43246 2 +Mismatch repair complex binding 0.5483369599005368 0.3198523454613707 0.7490802643522687 1.0 0.993846885745042 3 P12004,P43246 2 +Molecular function activator activity 0.361703644363686 0.3187590531215837 0.7499092306131561 1.0 0.993846885745042 12 O95433 1 +Atpase activator activity 0.361703644363686 0.3187590531215837 0.7499092306131561 1.0 0.993846885745042 12 O95433 1 +Growth factor receptor binding 0.3386787360912234 0.307304224369496 0.7586118205793608 1.0 0.9947076572362372 17 P05067,O00560,Q9Y639,Q9NZ08,Q92542 5 +Monocarboxylic acid transmembrane transporter activity 0.4181254206835728 0.3025025784414692 0.7622689681625958 1.0 0.9967574221783276 5 P53985 1 +O acetyltransferase activity 0.5402180053061802 0.2994813969025139 0.7645727641830207 1.0 0.9973211582802736 3 Q8NF37 1 +Acetyl coa c acyltransferase activity 0.3858163601981793 0.2899286016137756 0.7718708600137953 1.0 1.0 8 Q9BWD1 1 +Mannosyltransferase activity 0.392844985251553 0.2835891835427538 0.7767252272295502 1.0 1.0 7 Q9BV10,Q9BT22 2 +Cis trans isomerase activity 0.3255266280909988 0.2818252663340919 0.7780774961495631 1.0 1.0 25 Q9NWM8,Q8WUA2,Q02790,Q9Y680,P26885,Q96AY3,P62942,Q5T1M5 8 +Pdz domain binding 0.3456927643496035 0.2703135780112879 0.7869190203154615 1.0 1.0 14 Q15067,Q9Y4G8,Q9UQB8 3 +Phospholipid transporter activity 0.3963847240268031 0.2688266302263052 0.7880630994841162 1.0 1.0 6 P08183 1 +Insulin receptor binding 0.3932794026135588 0.257420048631829 0.7968545276721295 1.0 1.0 6 O14654,Q06124,Q13596,O60749,P18031 5 +Ccr5 chemokine receptor binding 0.6429459291485486 0.2559455643562632 0.7979928708085751 1.0 1.0 2 P42224 1 +Rna strand annealing activity 0.4043545878693624 0.2558870621377204 0.7980380450364677 1.0 1.0 5 O00571,P23588,Q06787,P51114 4 +Collagen binding 0.3700830932512478 0.2542894213043946 0.7992719718363621 1.0 1.0 9 Q92791,Q53GQ0 2 +Growth factor binding 0.3495735870878922 0.2542554020846074 0.7992982518068439 1.0 1.0 12 O43847,O00165,Q99523 3 +Carbohydrate kinase activity 0.3835945867276047 0.2469543167215038 0.8049435791550374 1.0 1.0 7 P52789 1 +Phosphatidylethanolamine binding 0.4306592039800944 0.2448342792493006 0.8065847505180275 1.0 1.0 4 P50995,A0FGR8,Q9BSJ8 3 +Ccr chemokine receptor binding 0.5141436120609355 0.2387664005188045 0.811286725253402 1.0 1.0 3 P42224,P48681 2 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.4275582630535034 0.2363902757110688 0.8131298412590768 1.0 1.0 4 Q15418 1 +Lipid kinase activity 0.6314481044126884 0.2329534068142933 0.8157975863976583 1.0 1.0 2 Q53H12 1 +Endopeptidase activator activity 0.3933404176883106 0.2205453629641397 0.8254464474269623 1.0 1.0 5 P61289 1 +Chemoattractant activity 0.5051290021759499 0.2195262435239247 0.8262401390235037 1.0 1.0 3 P14174,P26583 2 +Ribosome binding 0.3277001260743549 0.2176473044531517 0.8277039242651236 1.0 1.0 40 P46379,Q15070,Q969V3,Q9UHB9 4 +Bh3 domain binding 0.503885607709055 0.2169453682024428 0.8282509207454243 1.0 1.0 3 Q07812,Q07820 2 +Peptidase activator activity involved in apoptotic process 0.503885607709055 0.2169453682024428 0.8282509207454243 1.0 1.0 3 P53634,Q9BXK5 2 +Bh domain binding 0.503885607709055 0.2169453682024428 0.8282509207454243 1.0 1.0 3 Q07812,Q07820 2 +Potassium ion binding 0.38455102889431 0.1936699554672937 0.8464343184602361 1.0 1.0 5 P35610 1 +Alkali metal ion binding 0.38455102889431 0.1936699554672937 0.8464343184602361 1.0 1.0 5 P35610 1 +Intramembrane lipid transporter activity 0.4896178091182699 0.1886171683732961 0.8503928759263215 1.0 1.0 3 P08183 1 +Acidic amino acid transmembrane transporter activity 0.40360696517412 0.1757132331979636 0.8605192384748703 1.0 1.0 4 Q9H936,O75746,Q9UJS0 3 +L aspartate transmembrane transporter activity 0.40360696517412 0.1757132331979636 0.8605192384748703 1.0 1.0 4 Q9H936,O75746,Q9UJS0 3 +Rna polymerase ii general transcription initiation factor activity 0.37311217517617 0.1605603673767696 0.8724396720671912 1.0 1.0 5 P35269,Q9Y6J9 2 +Protein phosphatase 2a binding 0.3405604165391618 0.1575171166860278 0.8748373191175653 1.0 1.0 10 Q86XL3 1 +Mrna 3 utr au rich region binding 0.3299734559782213 0.1559419796491942 0.8760787550837925 1.0 1.0 12 Q92945,Q14103,Q13151,Q96B26 4 +Acyltransferase activity 0.3118229074246487 0.1508052971282482 0.8801293075551495 1.0 1.0 57 Q96N66,Q9BWD1,P23786,Q8NF37,Q8NCC3,Q86UY6,P35610,Q9NUQ2,Q6P1A2,Q96G23 10 +Dna replication origin binding 0.3382254358116526 0.1473938101176752 0.8828211909744381 1.0 1.0 10 Q9BQ67,Q9Y619,O75419 3 +Sumo transferase activity 0.4647186820018703 0.1449567742512683 0.8847450003864539 1.0 1.0 3 P49792,Q96MF7 2 +Phosphoprotein binding 0.3033775862411747 0.1433332663517564 0.8860269843181643 1.0 1.0 24 P31946,Q13526,P14314,O95104,P62258,P46109,P42345,P22681,Q9Y4P3,Q06124,P11717,P11171,Q9Y2W1,P29372,P07948,P43034,Q9NWS0,Q02790,P46108,P27361,P07737,P62993 22 +Nadplus kinase activity 0.4588125582841206 0.1356888117175192 0.892067292870153 1.0 1.0 3 Q53H12,Q9NRA0 2 +Carbohydrate binding 0.3156700993912076 0.1228666089032785 0.902212727472373 1.0 1.0 44 Q8N4A0,P13674,P35613,P52789,Q9NPA0,P10253,O75503,Q13438,Q10472,P27824,O14735,P17858 12 +Mirna binding 0.3165300455291636 0.1172825599092326 0.9066361448219504 1.0 1.0 14 P22626,Q9BWF3,P09651,P43243,P98175 5 +Metal dependent deubiquitinase activity 0.3473389355742273 0.1171484356728623 0.9067424278293748 1.0 1.0 7 O00487,Q7L5N1,Q6P2Q9,O00303,Q92905,O15372 6 +Oxidative rna demethylase activity 0.5543816034804356 0.1155018075087103 0.9080473878817736 1.0 1.0 2 Q6P6C2 1 +Sh2 domain binding 0.3442060325292722 0.1070874716922687 0.914719586152525 1.0 1.0 7 P46108,Q07666,Q8NEM2 3 +Prenyltransferase activity 0.320353734566927 0.1018019901826676 0.9189138459224416 1.0 1.0 11 P49356,Q86SQ9,P49354,Q9Y5Z9 4 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.3162779023804338 0.0924095434694824 0.9263726572824926 1.0 1.0 12 Q8IXJ6,Q13510 2 +Non membrane spanning protein tyrosine phosphatase activity 0.5298321939092733 0.0910431133483989 0.9274583337862696 1.0 1.0 2 Q06124 1 +Wd40 repeat domain binding 0.3612258201653968 0.0894254258815875 0.9287438174856706 1.0 1.0 4 Q96K76 1 +Phospholipid transfer activity 0.5248601615910645 0.0867825444742877 0.93084436276239 1.0 1.0 2 P48739 1 +Protein kinase a catalytic subunit binding 0.3375855631611678 0.0801136586482576 0.9361468596354652 1.0 1.0 6 P13861,P15311,P49840,P10644,P49841 5 +Phosphatidylinositol 3 kinase regulatory subunit binding 0.5146053449347514 0.0786890336019408 0.9372799683498776 1.0 1.0 2 P22681 1 +Protein kinase a regulatory subunit binding 0.3307503050654582 0.0769355188257136 0.9386748413365064 1.0 1.0 8 O43823,Q9ULX6,Q9H3P7 3 +Phosphatidylinositol monophosphate phosphatase activity 0.4096984768417897 0.0744228413313634 0.9406739344451742 1.0 1.0 3 Q9NTJ5,Q9C0I1 2 +Rage receptor binding 0.504972032318225 0.0719001109940013 0.9426814017195144 1.0 1.0 2 P26583 1 +Sumo ligase activity 0.4956494717215769 0.0660381459454731 0.9473474556510452 1.0 1.0 2 Q96MF7 1 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.3966529069236545 0.062632887445309 0.950058840425807 1.0 1.0 3 P46977 1 +Hormone receptor binding 0.4885021752641549 0.061988730525558 0.9505718064802516 1.0 1.0 2 Q06124 1 +Peptide hormone receptor binding 0.4885021752641549 0.061988730525558 0.9505718064802516 1.0 1.0 2 Q06124 1 +Molybdopterin cofactor binding 0.4850839030453855 0.0601820486185456 0.9520106429240398 1.0 1.0 2 Q5VT66 1 +Single stranded dna 3 5 exodeoxyribonuclease activity 0.4847731510254974 0.0600218606331733 0.9521382238093392 1.0 1.0 2 Q07864 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 0.3251626812184972 0.0587445952854389 0.9531555387457638 1.0 1.0 8 P16260 1 +Scaffold protein binding 0.2866443265959409 0.057644900886603 0.9540314833780028 1.0 1.0 19 P07602,Q9UQB8,Q9NZJ7 3 +Map kinase scaffold activity 0.3395522388059632 0.0560553732156517 0.9552976950195712 1.0 1.0 4 P46940,O60271,Q02750 3 +Oxidoreductase activity acting on a sulfur group of donors 0.2948587771785128 0.054319543977407 0.9566805786976358 1.0 1.0 28 Q96JJ7,Q9H3N1,Q9UHG3,Q8NBM8,P78417 5 +Thiol oxidase activity 0.3857631333540648 0.0540969931332239 0.9568578878736288 1.0 1.0 3 Q6ZRP7,P07237 2 +Sulfate binding 0.4639527656929937 0.0507289921727556 0.9595414739725084 1.0 1.0 2 P15586 1 +Protein arginine omega n asymmetric methyltransferase activity 0.3804787068697586 0.0503600353063575 0.959835483158506 1.0 1.0 3 Q99873,Q86X55 2 +Deacetylase activity 0.3201920514380231 0.0368149329051627 0.9706325673836282 1.0 1.0 7 Q8IXJ6 1 +L serine transmembrane transporter activity 0.4033561218148109 0.0361406874525241 0.9711701796096426 1.0 1.0 2 Q9H9B4 1 +General transcription initiation factor activity 0.3192283758556233 0.0346039372802288 0.972395561886136 1.0 1.0 6 P35269,Q00403,P29083,Q9Y6J9,P17480 5 +Glucocorticoid receptor binding 0.3781852082038632 0.033610865246902 0.973187457950572 1.0 1.0 2 Q02790 1 +Acyl coa dehydrogenase activity 0.3168330661658937 0.0329678048724184 0.973700261668104 1.0 1.0 8 P49748,Q9NZ01 2 +Long chain fatty acyl coa binding 0.347731510254831 0.0320155071895608 0.974459684287888 1.0 1.0 2 O00154 1 +Transmembrane receptor protein kinase activity 0.2924176507147424 0.0310923097546627 0.9751959226328504 1.0 1.0 2 P11717 1 +Transmembrane receptor protein tyrosine kinase activity 0.2924176507147424 0.0310923097546627 0.9751959226328504 1.0 1.0 2 P11717 1 +Phosphatidylinositol kinase activity 0.331619396444426 0.0265355806434418 0.9788301543338868 1.0 1.0 3 P42356 1 +Dihydropyrimidinase activity 0.3232825613926034 0.0240691502938424 0.9807974506897316 1.0 1.0 3 Q16555,Q9BPU6 2 +Tropomyosin binding 0.3155113459745163 0.0220974030657722 0.9823702580247866 1.0 1.0 3 Q9NYL9,P28289 2 +Acetyl coa hydrolase activity 0.2969622292625217 0.0184846985995163 0.9852521842301168 1.0 1.0 3 O14734 1 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.2965495803543708 0.018419691734527 0.9853040433746856 1.0 1.0 3 P17480,Q9NWS0 2 +Sulfurtransferase activity 0.3039351648374228 0.0162308475818085 0.9870502258905338 1.0 1.0 4 P25325 1 +Structural constituent of postsynapse 0.3064276160090069 0.0139728749564483 0.9888516215739293 1.0 1.0 5 P07196 1 +Ubiquitin conjugating enzyme binding 0.3057032426820709 0.0011148765647316 0.9991104573860758 1.0 1.0 8 Q9Y679 1 +Signaling receptor regulator activity 0.2884431770440322 0.0005106069141705 0.9995925946442472 1.0 1.0 15 Q92520,Q9UMX5,P05067,P43490 4 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1e2420dc2a33ef783d622a45b54e2d34ec22d863 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chondroitin sulfotransferase activity", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein lipase activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Platelet derived growth factor receptor binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Steroid hydroxylase activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Store operated calcium channel activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPV", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GID8", "GIGYF2", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIKESHI", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDRG1", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", 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21.026699029126213 99.08495145631068 0.338494152708191 0.5916975591038598 7.650862365043173 8.679854297666031 0.9096277682010132 0.3494553445560299 0.001056914744378 0.1357113467114961 0.0141203510166531 0.0515596375225491 0.0001637339304192 +Optic disc pallor 14 54 2.3475008645848856 0.0188998292930073 14.480582524271844 48.592233009708735 1.02733963234224 0.3801436604957769 5.692535706296588 6.181615230530596 1.3595924408188145 0.3692839687174071 7.832237546083141e-05 0.0002995688944249 0.0011858256231916 0.0001587658980404 0.0007408569565356 +Abnormal conjunctiva morphology 7 24 2.3395446629477386 0.0193072629061816 6.997572815533981 26.58495145631068 0.5265054436970301 0.4429378103171669 2.669041123051977 2.4927208099742058 1.133049116684961 0.3300379664677785 0.0258330005231254 0.3744891089864141 0.0664204872480981 0.0794624934300223 0.089909804573414 +Increased cerebral lipofuscin 4 5 2.333751675392941 0.0196087285241544 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 0.0001541627914423 0.0479914252810258 0.0001045037164678 6.194004931981708e-05 5.436360967141595e-05 +Abnormality of the mitochondrion 23 99 2.3153904456775254 0.0205915739266095 24.216019417475728 91.8883495145631 0.797381253925538 0.4153343301115782 10.704523845407817 8.200885590005743 1.4941762160347407 0.3812617801525748 8.679273129526862e-06 0.0001307121217589 0.0051169884297825 0.0001461318064328 9.224446519004429e-07 +Peripheral demyelination 5 17 2.302652199491422 0.0212984196691181 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 0.0277469460726432 0.0148056693212618 0.0060217503205503 0.0128293519549119 0.0093317531476842 +Dementia 23 61 2.286402566265212 0.0222307183440808 17.021844660194176 58.19174757281554 0.9978727756866732 0.3214313161707923 5.814027938449679 5.568168011495494 1.793982160512653 0.3770196158976925 0.0031022925635837 0.145012854682081 0.0110705878241367 0.0058885527356408 0.0003323646209297 +Abnormal circulating cholesterol concentration 11 35 2.281400592124648 0.0225247530396677 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.007735867825346 0.0058478787222266 8.922499786531232e-05 0.0021480935661603 0.0002394821511088 +Hemivertebrae 4 12 2.2799607220533185 0.0226100181238226 3.512135922330097 11.783980582524272 0.6301475240174538 0.4485350988347466 1.996926838183888 1.5262860818032955 0.9074280753889176 0.307982460828651 0.1086335237092403 0.1706778675257841 0.0532804729840314 0.0630731351339203 0.0353817250131281 +Unusual infection by anatomical site 4 12 2.2774238999934098 0.0227609242355091 3.907766990291262 13.49271844660194 0.7293808434681487 0.4605880442375236 1.9820157102817233 2.372464489866843 0.7897149485111757 0.3081613942392058 0.0543155078320594 1.0 0.3714211816154574 0.1038817567329197 0.0762091064419948 +Anencephaly 7 16 2.273739807314737 0.0229816352409433 3.650485436893204 14.604368932038836 0.3352672102861634 0.6079749637780152 2.1608104280798432 2.3783571754848793 0.7012631526775229 0.2872057368613228 0.077594322161697 1.0 1.0 0.135543868878084 0.0135499856307104 +Splenomegaly 22 86 2.2678425762991825 0.0233388033455719 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 0.0112381238073923 0.6829262542482903 0.1912250381470315 0.010203975961045 0.00868857582787 +Respiratory distress 18 52 2.267185153741717 0.0233789173749008 12.805825242718448 52.09466019417476 0.6386570898760532 0.4437575130669694 5.288397728288474 5.051988998968333 1.24726945526474 0.3693239953771813 0.0002213802834264 0.1399625708529587 0.0020000579856151 0.0051017818302581 2.3826814668037323e-05 +Abnormality of the alveolar ridges 4 6 2.265083424623337 0.0235075605869996 2.1092233009708736 6.368932038834951 1.3424122348723253 0.2105791674194365 1.182482323454481 1.3741037061958896 0.9200079991465796 0.2386077675723682 0.2211054645003494 0.1330370821365251 0.2489059409173845 0.5079876539292768 0.0119362160344991 +Abnormality of glycolipid metabolism 4 7 2.2626329988401483 0.0236583221831179 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 0.0028755778106474 1.0 0.0938999510605359 0.2167775624926856 0.0009118158302113 +Biliary tract abnormality 9 27 2.2624703892193776 0.0236683562995676 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0130508773291006 1.0 0.1300768221953693 0.0043231258251732 0.0009461366743176 +Epiphyseal stippling 7 14 2.262316625712117 0.0236778479471975 4.638349514563107 12.094660194174756 1.0555865796987824 0.32401635996293 2.3050778042540805 1.737163917644219 0.9677864882437331 0.2966156619887163 0.0110460269750891 0.1330370821365251 0.0325598174288622 0.0048864602536943 0.000373895250662 +Mitochondrial inheritance 1 5 2.2620198805972755 0.0236961750250597 1.577669902912621 4.247572815533981 0.9928856357718184 0.2727497270810077 1.119676794457053 1.2095369137272214 1.2442723588935711 0.2811589341958167 0.0749917232739195 0.0023758658868836 0.009201700056446 0.0495157384890535 0.1630814235328921 +Abnormality of circulating adrenocorticotropin level 2 6 2.250590242065643 0.0244115020256197 2.6067961165048543 8.526699029126213 0.4678017709762634 0.488215339376942 1.5566183247401906 1.8673915603090907 0.8467951338817273 0.2872828179813482 0.5932632212061931 1.0 1.0 0.5079876539292768 0.1645088237572309 +Ventricular preexcitation 3 8 2.247995882593224 0.0245764524679621 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.0189572928019038 0.0038211367015083 0.0146091852998709 0.0757571260003459 0.0118865434534573 +Cherry red spot of the macula 6 9 2.245630771113499 0.0247276678157504 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 0.0003461886533046 0.0573151884822011 0.000188873280149 0.0025975272437437 0.0001575214550341 +Ascites 8 24 2.242261500878418 0.0249444764029991 6.538834951456311 25.800970873786408 0.2860997134153194 0.2561597752608451 2.6559964399945706 3.331112387328855 1.6846905274497244 0.2824645045304154 0.0651694936269209 1.0 0.1536294983436044 0.02815445047553 0.0559308134519845 +Ambiguous genitalia 10 22 2.2412680388256216 0.0250087179426816 4.87621359223301 21.094660194174757 0.6419151331050246 0.5170922748249285 2.593254362261455 3.0850832203953606 0.7584464446429787 0.3063377806646535 0.2405265061057818 0.3328373805982222 0.5557866832475982 0.592458577023541 0.0175418047376826 +Calcinosis 1 5 2.240699538501832 0.0250455440272447 1.5072815533980584 5.099514563106796 1.1513451038285936 0.2590169313384529 1.041584579038491 0.4030222683885372 0.953608514142629 0.2639318719258676 0.0354995311595153 0.0479914252810258 0.004071454093033 0.0229613270793894 0.0817606313480972 +Lacticaciduria 2 6 2.238359794672641 0.0251976016775377 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0097377531702328 0.0023758658868836 0.009201700056446 0.0050923434600555 0.0334620993119388 +Abnormality of the vasculature of the eye 21 71 2.237911736188051 0.02522681154557 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 0.0100940410370059 0.1007403353395005 0.0244752238801974 0.1007206487772324 0.0151365479882038 +Dyschromatopsia 1 6 2.23720162338958 0.0252731653149236 1.9563106796116505 6.881067961165049 0.8116181676256156 0.3616454151850379 1.3027357251175682 1.008666728011197 0.9552278076961072 0.2951208666933738 0.0425293714029277 0.0012601973854463 0.0049445172385496 0.0276231155809849 0.0968157430558884 +Visual loss 12 49 2.236693205282843 0.0253063984019572 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0029220024931586 0.0408125099476932 0.0185077935269698 0.0132467171015694 0.0400326383408667 +Abnormality of temperature regulation 22 99 2.218771567563562 0.0265022692701135 19.25485436893204 102.82038834951456 0.3970293406250321 0.5993116835261848 7.1176384711487035 9.956544993053525 0.8850362554833304 0.3476784016267602 0.0592080915797608 0.4164875911711549 0.1541180378169463 0.0229536495466617 0.0134886378229145 +Abnormal circulating citrulline concentration 2 5 2.2151671002588182 0.0267485971580063 1.519417475728155 4.283980582524272 0.9322911204120568 0.2795135602214257 1.0297099461920487 1.0355035731992424 1.235992875942202 0.2843671782204088 0.0050382705358123 0.0015075035399645 0.0058956460302812 0.0025975272437437 0.018020673376298 +Undetectable electroretinogram 2 5 2.204825437919353 0.0274663462858835 1.7427184466019416 4.415048543689321 1.0664751707047182 0.1916317897201908 0.9612998826677368 0.7632752290710167 1.383034454070232 0.2429274936147374 0.0064033235801391 0.0619434524836269 0.1203280145079081 0.0379575415698398 0.0225979674873623 +Corneal opacity 25 53 2.202105446932415 0.0276578608202988 15.480582524271844 53.95631067961165 0.9517965339960472 0.3644495779961974 5.277458167452316 6.791845051563607 1.5225460520633525 0.3686110256368129 0.063840975329977 0.2370016515803348 0.283187038525853 0.1725968058553044 0.0020698905923621 +Progressive psychomotor deterioration 4 8 2.196932770315893 0.0280252480177289 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.050027591577048 1.0 0.1116045715736199 0.032628233248221 0.018020673376298 +Action tremor 14 57 2.1968288726636995 0.0280326701937481 13.143203883495143 54.47572815533981 1.1235280535029035 0.3645421720231636 5.4627047451961745 5.814853194507433 1.1817578847970691 0.3688885139588422 0.0006481680454005 0.026201726433941 0.0017828183273307 0.0012466860629514 0.0016801748699389 +Elevated pulmonary artery pressure 4 19 2.1959096465772725 0.0280984111375888 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.1354074002415757 0.0704839558103872 0.2171594264364444 0.0637395822669413 0.2633668774735583 +Reduced visual acuity 21 111 2.185139273709522 0.028878636412134 25.553398058252423 114.88106796116504 0.4786956822479749 0.5063280215354549 8.433035081523723 11.838637206126975 1.2158495541746812 0.3830713742278179 0.004182004947062 0.0063277455662865 0.0192453895113126 0.0191082850784067 0.072372499510893 +Left ventricular systolic dysfunction 3 7 2.180912227171609 0.0291899091652447 2.0024271844660193 6.274271844660194 0.8306323903703577 0.3188570764916028 1.4472920586220064 1.367095356040773 1.072243004538969 0.2702909744520516 0.1438693650633994 0.1026081339138497 0.1951188871774342 0.097689242801984 0.0200033311952484 +Slow decrease in visual acuity 2 7 2.1759807188646603 0.0295567023242895 2.313106796116505 7.985436893203883 0.7332483742783148 0.3617245659278226 1.567733834853386 1.5547551717475598 1.083959755774155 0.2999488674407273 0.0393705518794579 0.0065792573185243 0.0246740936940832 0.1211421538065826 0.1188827437046941 +Fluctuations in consciousness 2 7 2.1605697277017546 0.0307285919606212 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0189572928019038 0.0892490045576324 0.1709159600444602 0.0757571260003459 0.0618109910728358 +Abnormality of the umbilical cord 3 8 2.158138822514832 0.0309170401437206 2.3276699029126213 7.713592233009709 0.8125665705120105 0.3888135484058521 1.4654305864343329 1.3565768271996297 0.908107514682906 0.2917208108772662 0.1874080902331407 0.1201219647894398 0.2263045436956677 0.1292409073430241 0.0351238878380088 +Abnormality of pulmonary circulation 5 22 2.1565006137134115 0.0310445959037497 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.1085134562610171 0.0966324665930835 0.2825796829681516 0.0446619282438801 0.2630004164211381 +Abnormal brainstem mri signal intensity 7 22 2.156167530571588 0.0310705859202324 6.252427184466019 20.32281553398058 0.9466857218441096 0.334812084954676 2.9078682900486936 2.582646312540884 1.1241621585657078 0.2967087697298931 0.0001075189267489 0.0140700862732742 0.0055856505984271 0.001820540651884 0.0003233683313873 +Decreased activity of mitochondrial complex iv 4 18 2.15067939164239 0.0315015140805312 3.878640776699029 15.9247572815534 0.8034271187166634 0.3445303465767608 2.844656052218728 1.5238137800378977 1.1422119451186783 0.2970372577525856 0.0014102786979957 0.0003334624710947 0.002509898486982 0.0004897389809093 0.010278445998416 +Increased serum pyruvate 12 36 2.144961516764295 0.0319559240050646 9.303398058252426 32.64563106796116 0.7845790996019184 0.387018609503293 3.945341127018032 3.24570744750092 1.0586848930233297 0.3138975633269482 1.0532005710494018e-08 3.0348447644900237e-06 5.935848101169321e-06 1.3157778505076486e-07 2.192271601565118e-07 +Retinal vascular tortuosity 6 16 2.1449585422772923 0.0319561618475789 3.495145631067961 14.25728155339806 0.5904651339279154 0.4721906216948602 2.0650761588615536 2.517284017277412 0.91909598108814 0.3171023435283937 0.1646257160382742 0.0212633176973237 0.0746250944081647 0.3051232152156647 0.0228888281479028 +Mucosal telangiectasiae 4 9 2.1351465048920164 0.0327490449678016 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0524814200598482 0.1287528218161406 0.0305060181117638 0.1457934990596532 0.010278445998416 +Lower limb hypertonia 1 10 2.128303218711149 0.0333119514178239 3.1019417475728157 10.560679611650484 0.3457861267289759 0.578509512407923 2.473999967919734 1.118558158372637 0.7853139694401313 0.305800517077934 0.1874080902331407 0.1201219647894398 0.0265618978442646 0.1292409073430241 0.3621483333283614 +Abnormal pericardium morphology 3 9 2.1280876775910444 0.033329814791001 3.487864077669903 10.762135922330096 1.0304485268572945 0.2849705132346721 1.7172308655515107 1.695717994097398 1.0794817436655069 0.2735310781030822 0.0840515145978115 1.0 1.0 0.0479498850625808 0.0807266025333323 +Raynaud phenomenon 1 6 2.123628521709344 0.0337012186339502 1.5145631067961165 6.242718446601942 0.9919476180863708 0.3155318164932874 1.0668352405519568 0.7236104114257896 0.8937818768405142 0.2739634297108673 0.0749917232739195 0.0711332726649859 0.009201700056446 0.0495157384890535 0.1630814235328921 +Lower limb spasticity 21 87 2.123194692863131 0.0337375405148996 17.24271844660194 80.34466019417475 0.5234592060757025 0.5553383930423336 6.384471482056576 8.884788223572686 0.9712236167697867 0.3629508150226985 0.0041552152985446 0.0611306223273009 0.009359912662931 0.0049863628675692 0.0015154633182365 +Color vision defect 1 12 2.1221959046459387 0.033821290323788 4.04126213592233 14.099514563106796 0.5067594972559855 0.4612749614061434 2.1007965108092805 2.354978151586148 0.920945555170958 0.3013565918016589 0.43287175482947 0.0230307909850112 0.0803264485176453 0.3229860752427858 0.6842653425207743 +Sensorimotor neuropathy 9 34 2.116467510100516 0.034305065634435 8.980582524271844 31.118932038834952 1.3016328701661894 0.3009249972125085 3.646997920951252 3.5836645053134393 1.2437208862143418 0.3260038325488978 0.0196324126676354 0.046072228335376 0.0048690104254232 0.0067097031977977 0.0019108778393583 +Abnormal csf protein level 5 13 2.116223696023251 0.0343257867914554 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.1151696921634261 0.1747599807978781 0.0558103535730672 0.0671599559498881 0.0105883475769395 +Broad palm 4 6 2.115166576251699 0.0344157525508577 1.9951456310679612 6.810679611650485 0.8447038493260335 0.3335088320973898 1.1679272687137603 1.380545313769426 0.9814334548432692 0.2724793488094146 0.1545530381620926 1.0 0.0210734332562196 0.1053546389470493 0.0042957165481444 +Adrenal hypoplasia 1 9 2.112394547688021 0.0346526222720224 1.8519417475728157 8.186893203883495 0.3852327899897437 0.5464880134936936 1.550108394739415 1.256641794723172 0.7382232570467291 0.2693753067389556 0.1438693650633994 0.1026081339138497 0.1951188871774342 0.097689242801984 0.2898287915273368 +Fetal ultrasound soft marker 10 19 2.110945101706601 0.0347770308218566 4.771844660194175 17.186893203883496 0.354928613195039 0.5805758515767048 2.3506626818475485 3.6485830549657137 0.7673664734584956 0.2977103399110563 0.664811038514784 0.3058671484100957 0.5190509805854646 0.5365210756997536 0.1492508258365027 +Abnormality of corneal stroma 7 13 2.109926915471517 0.0348646514845727 4.733009708737864 13.131067961165048 0.6716440045814968 0.2233795964932449 1.7589100966397004 2.506749302052849 1.61853564814875 0.2527544669587041 0.1050608843056718 0.2523879312119707 0.1138374922433585 0.053649406266927 0.0654262733188917 +Hypersplenism 3 8 2.1000541047586374 0.0357240819523201 2.7184466019417477 7.970873786407767 0.2142260937784027 0.1548364087136437 1.1589036979530396 1.1444786041391362 1.8316571038254568 0.2005205006822401 0.0117182537853428 1.0 0.1459927402947744 0.0061570039439817 0.0062633876942655 +Dystrophic toenail 0 6 2.0988828790006444 0.035827226461194 1.220873786407767 5.543689320388349 0.692189932800709 0.390030635448346 1.3855184489640129 0.8276378719992816 0.921193258391654 0.2804952362251065 0.3520614836486821 0.066549445548378 0.1289666473793992 0.2897526236095206 0.5020158400168588 +Abnormal auditory evoked potentials 3 9 2.098711515486577 0.0358423389417204 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 0.1230215118243738 0.0937235599037543 0.0161297090986061 0.0828772873031817 0.0143001062154138 +Delusions 4 18 2.0950754195488552 0.0361642886191588 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0899509529230909 1.0 0.0459506122728715 0.051542815486873 0.0257423149537502 +Abnormality of hepatobiliary system physiology 19 86 2.0928300217476186 0.0363643308181051 18.737864077669904 78.23543689320388 0.6753867917166245 0.4584905924436965 8.191827759406172 8.347745847320367 1.279744288983872 0.374212423907768 6.522080763476191e-05 0.0065722437922867 0.0171603994289533 8.173518037011231e-05 4.85630921879424e-05 +Abnormalities of placenta or umbilical cord 6 16 2.0882538475397627 0.0367749422721914 3.703883495145631 15.434466019417476 0.6748523820908133 0.4577828483842401 2.098238851439167 2.085101207366641 0.8521769849823545 0.3006675269511061 0.43287175482947 0.2106238865633207 0.3776146865857887 0.3229860752427858 0.0818539267356338 +Muscle abnormality related to mitochondrial dysfunction 12 40 2.0856402165618024 0.0370112255365324 11.12378640776699 35.58252427184466 0.9791864828781052 0.3365990386989574 4.6259837298613 4.333263242301439 1.4740065920951253 0.3430734831138388 4.281991309150906e-06 0.0040870836872518 0.0268391045488713 2.669458491354557e-05 1.3656105597610355e-05 +Mania 6 14 2.08298770551938 0.0372523442302241 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.2438347296531995 0.141543756104335 0.2636091346473535 0.1713585638073601 0.0033138804057902 +Hyperextensible skin 3 14 2.078169805633471 0.0376937220715121 3.6237864077669903 15.143203883495143 0.4300675673044501 0.5285935310652697 2.0185348028941346 1.904613057862172 0.8224947593752617 0.3015375840807006 0.0654113117108624 0.2183837422916212 0.0128572972549699 0.03203241935523 0.2236139420972091 +Pulmonary infiltrates 2 6 2.0701203507322705 0.0384410755819197 2.203883495145631 7.41747572815534 0.5937593446740285 0.3342650103364393 1.20966354385806 1.2445943063002318 1.1896790379366604 0.2811562889912624 0.0435317720090838 1.0 0.2263045436956677 0.0239571113561098 0.1298078118605267 +Abnormal lower motor neuron morphology 2 7 2.06916350010834 0.0385307465637527 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0393705518794579 1.0 0.0246740936940832 0.1211421538065826 0.1188827437046941 +Hyperventilation 1 5 2.068955028310705 0.0385503070065615 1.5121359223300972 5.842233009708738 0.257199533402791 0.3684899252913141 1.1070595624125217 1.4234045280807717 1.1968077455675237 0.2703462773314473 0.1545530381620926 0.0055832614279084 0.0210734332562196 0.1053546389470493 0.3080842130268088 +Limb ataxia 7 24 2.068402323125669 0.0386022069498515 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0088962393008072 1.0 1.0 0.0028705350867404 0.0073008402117251 +Neuronal loss in central nervous system 4 11 2.0659338653963006 0.0388347246488709 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0124461106964641 1.0 0.2562935091164666 0.0348798008289802 0.0137665493817408 +Submucous cleft of soft and hard palate 6 24 2.065750059844289 0.0388520858094558 5.138349514563107 22.941747572815533 0.8980380147163236 0.4007892874523231 2.272201189765468 2.581958475140233 0.7850752745431548 0.2945527466716488 0.0029380650506994 0.0380696669646128 0.1267862934099702 0.0177220872628324 0.0322356046235818 +Generalized joint laxity 2 11 2.0555745664304967 0.0398235414140946 2.7815533980582523 11.79368932038835 0.6564693612664338 0.4622151090919249 1.854108404410052 1.1421572930726116 0.9213406108825204 0.3139838952541599 0.2098059446663725 0.1287528218161406 0.0305060181117638 0.1457934990596532 0.1526461610854137 +Pericardial effusion 2 5 2.0551313603950843 0.0398663186258336 1.9466019417475728 5.980582524271845 0.6333430474464145 0.2773316461993735 1.2136213588737947 1.4646685732948297 1.3006352977804805 0.2635985168358294 0.1438693650633994 1.0 1.0 0.097689242801984 0.088385561156941 +Cognitive impairment 60 174 2.0497152372450405 0.0403922272227723 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 6.790030260286634e-06 0.1779583843155386 0.0044893506630742 3.151186547098943e-05 2.790327776500665e-06 +Abnormal metabolic brain imaging by mrs 5 20 2.047810722944758 0.0405785492583818 4.606796116504855 16.54854368932039 0.7235353195513555 0.4019359214719802 2.5477483733613684 2.1144608015049493 1.0143737900681629 0.2966800307492503 0.0191572938808404 0.0119629297909749 0.004393919895815 0.0479498850625808 0.0053527619374205 +Abnormal circulating long chain fatty acid concentration 5 8 2.0448520817484224 0.0408694433028291 2.0728155339805827 4.861650485436893 1.0288291622755297 0.284696092465088 1.384567800831184 1.563474222630441 1.0358408470651057 0.2764983518284591 0.0933798021105754 1.0 1.0 0.0621585272883563 0.0465653262864464 +Microretrognathia 2 16 2.0333241609834216 0.0420197837447939 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1.613102851845623 0.7481836900008295 0.2981059590210475 0.0393705518794579 1.0 0.2186221342412543 0.0215683584236732 0.0308662830144804 +Broad foot 2 6 2.016770505752853 0.0437194682296067 2.3300970873786406 9.016990291262136 0.256328891212772 0.5237546105785787 1.7131039762059068 1.5223903885177978 0.8992937610865464 0.290191176620823 0.1874080902331407 1.0 0.2263045436956677 0.1292409073430241 0.1298078118605267 +Impaired proprioception 11 43 2.0162240489524725 0.0437765527684925 9.813106796116504 38.25485436893204 1.0894904790984437 0.3853358407663543 4.186376779745541 5.223695147901442 1.052731732437443 0.3596256989246241 0.0064868922246931 0.0099608681798937 0.0599224496562618 0.0015514010815503 0.0014314583392422 +Increased intracranial pressure 4 15 2.007803017842825 0.044664228033868 4.483009708737864 18.225728155339805 0.6089364319190148 0.5193135356051898 2.352895895910637 2.1988563231789326 0.7556358037224847 0.3144749703857186 0.5321540048269278 1.0 0.4363210249842685 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0.0469507740789212 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.2666522144656411 1.0 0.2780273254227372 0.5539124029112868 0.0203628052401783 +Abnormal activity of mitochondrial respiratory chain 13 58 1.986497741335932 0.0469780833818944 14.847087378640778 52.86407766990291 0.7821137838412346 0.382257667326437 7.203923975365814 5.31995427327111 1.5049815702887546 0.3635380021892623 2.138532524970192e-05 8.244447906262265e-05 0.0020569485401092 7.074199918744216e-05 3.2772030765973025e-05 +Abnormality of lysosomal metabolism 3 5 1.9841058822171365 0.0472440375312566 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.0020591533048899 1.0 0.0032780640178306 0.0010464818333657 0.0005688349419973 +Stillbirth 4 11 1.9837262511129836 0.047286365462781 3.145631067961165 11.177184466019416 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0.3473011798108487 3.936575202939786 3.974666305559559 1.3336232032537867 0.3216890657230479 2.3588257113643183e-05 0.002071073147083 0.0142951840993497 0.0002314913891327 3.11780669585079e-05 +Morphological abnormality of the corticospinal tract 4 17 1.97705991165634 0.0480348584693817 3.686893203883495 15.03883495145631 0.5616218245613079 0.5231151147988415 1.9487419537195845 1.7976377708768945 0.8440336488225383 0.3280840546625515 0.1721468665961035 0.0221396463904123 0.0774589481602222 0.3140672800286707 0.0762091064419948 +Abnormal placenta morphology 1 8 1.976880490345306 0.0480551405911433 1.944174757281553 8.475728155339805 0.7648192021909558 0.3426805830523109 1.4036326133106245 0.983797478904342 1.0207702392187767 0.275511162241509 0.1438693650633994 0.1026081339138497 0.1951188871774342 0.097689242801984 0.2898287915273368 +Abnormal saccadic eye movements 6 26 1.9768536015604992 0.0480581807697526 6.293689320388349 24.570388349514563 0.6352395547829492 0.4765898942028741 2.9458970942458165 3.3125821982342476 0.9514629694011908 0.3397171221111555 0.0045245212935941 1.0 1.0 0.0058282629537454 0.0460574281433519 +Pedal edema 2 5 1.974989955640425 0.0482692878829671 2.092233009708738 7.211165048543689 0.6115824815809859 0.289867756561444 1.3297338459429695 1.219410808682535 1.3115580791228945 0.2762999280116011 0.1874080902331407 1.0 1.0 0.1292409073430241 0.1298078118605267 +Severe lactic acidosis 1 5 1.974561698325848 0.048317909250882 0.6359223300970874 3.3228155339805827 1.0052898533279455 0.3334709507855445 0.8234847065541359 0.7759515517301849 0.9491462794560998 0.2761677714094095 0.0128252824702257 0.0003491251705821 0.0013923625346842 0.0081566962170519 0.0309764532364539 +Poor head control 16 76 1.969418343473893 0.0489050710097782 16.62864077669903 70.83495145631068 0.6551149189569596 0.4893764407721695 6.123760433086226 7.081833846449059 1.1601225008146194 0.3772060433763 3.780048431558648e-05 0.1603872358408925 0.0551678125894675 0.0008022847163198 0.0007003127864278 +Nonprogressive 1 5 1.9665521976153464 0.049234859040852 1.7548543689320388 6.233009708737864 0.5197538339444207 0.4920096159874214 1.3779120014158963 0.8089773419024573 0.8548269611597411 0.29929586178195 0.0579592766667772 1.0 0.1203280145079081 0.0379575415698398 0.1289341732663725 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6f49f490da8b4c6357c7a0b0589cf53a2c6a8f38 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 4569, + "title": "Average number of proteins per term", + "value": 23.554169402495077 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4d01913c863e5fc05e0a9d2b24c4345850423223 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ac025daa2d76b5ec320f928ee6b5f8be4de7c63a --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1633 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Abnormal circulating lipid concentration 0.5201380673484306 3.5578675218525277 0.0003738777830339 0.8188748423976282 0.7457746331090924 82 Q15125,Q9P0S2,O95470,P31751,Q9NVI7,Q15392,P06280,Q9Y4P3,O75844,P23786,Q8N511,P49748,Q9BV10,Q14739,Q15800,P07602,P28070,O43772,O75845,Q9UBM7,Q9Y5Y5,P50402,Q9NZJ7,O75381 24 +Mental deterioration 0.4888997904267926 3.0720499529614007 0.0021259414488601 0.9999401558110884 0.7457746331090924 104 Q9Y287,Q86SQ9,P35637,P03886,O15118,P04062,O95470,P00846,P06865,P50897,O75306,P22626,Q9NPL8,Q9BQE5,Q13510,O76024,Q9Y487,Q9NQZ5,P07602,Q10713,O75503,P10644,P21964,Q03164,Q14108,Q9NZJ7,Q9H2C2,P54802,Q5XKP0,Q7LG56 30 +Postural tremor 0.7245332076614048 3.0329670631913537 0.002421620294738 0.9999845484565736 0.7457746331090924 19 O75306,P35637,Q14108,P03886,Q9H6K4,Q9NR77,O14773,P00846 8 +Central scotoma 0.8153966100756557 2.929562903743305 0.0033943910220526 0.9999998209058256 0.7457746331090924 12 Q9Y287,P03886,Q9H061,Q9H6K4,P00846 5 +Bulbar signs 0.8269678155756911 2.920049825736251 0.0034997542570269 0.999999889519174 0.7457746331090924 11 P07602,P35637,P03886,P04062,P00846,Q99720 6 +Abnormal retinal artery morphology 0.6787436920466856 2.8620751936567768 0.0042087704227296 0.9999999957248772 0.7457746331090924 23 Q9Y4P3,P21964,P07602,P03886,Q9NZJ7,O00192,P10619,P00846,Q13510,Q9C0D9,P06865 11 +Clumsiness 0.6956273708631996 2.8552528358024074 0.0043002579820432 0.9999999971904616 0.7457746331090924 19 P07602,O00165,Q15067,O75503,Q9NR77,O14773,Q13510 7 +Scotoma 0.7556788188930907 2.8385929678193755 0.0045312917307693 0.999999999026887 0.7457746331090924 15 Q9Y287,P03886,Q9H061,Q9H6K4,P00846 5 +Myoclonus 0.4632551037585204 2.810770933055424 0.0049422958581544 0.9999999998525212 0.7457746331090924 99 Q86SQ9,P21281,P03886,P04062,Q9Y4G8,O14653,Q01105,P00846,Q96CU9,P50897,O96008,Q99757,Q9NPL8,Q13510,P00374,Q9NQZ5,Q9Y2B2,P07602,Q10713,O75503,P13073,O75845,O14773,Q8NI60,Q14108,Q9UBX3,Q9NZJ7,Q9H2C2,P11166 29 +Ragged red muscle fibers 0.6690613642485892 2.7933637703748726 0.005216299521277 0.9999999999580964 0.7457746331090924 20 P03886,Q9H2D1,Q70HW3,P12235,O95831,P00846 6 +Psychomotor deterioration 0.8252858469868417 2.7527291098736892 0.0059100776592424 0.9999999999982706 0.7457746331090924 10 Q03164,P07602,Q9Y487,Q9NZJ7,P06865,P50897 6 +Avascular necrosis 0.6596234263851718 2.7322403896495446 0.0062905224937701 0.9999999999996992 0.7457746331090924 20 Q14108,O75844,P04062,Q9Y619,Q9NZ08 5 +Abnormal epiphyseal ossification 0.6744339713100996 2.7225219666457146 0.0064785726247682 0.9999999999998732 0.7457746331090924 19 Q9Y5Y5,Q15125,P38435,Q7RTS9,O75381,Q96HY6,P10644,Q14739,Q9UBM7,Q9UG56 10 +Increased bone mineral density 0.6538516414634886 2.704915774489705 0.0068321710000318 0.9999999999999752 0.7457746331090924 25 P51798,Q15125,Q14108,P04062,Q13126,Q14739,Q15392 7 +Abnormality of head blood vessel 0.6532967959365823 2.7011945020958588 0.006909092058094 0.9999999999999823 0.7457746331090924 25 Q9Y4P3,P21964,P07602,P03886,Q9NZJ7,O00192,P10619,P00846,Q13510,Q9C0D9,P06865 11 +Abnormal tissue metabolite concentration 0.6579894231063286 2.6180735754233413 0.0088427736453147 1.0 0.7457746331090924 19 P56589,Q9Y5Y5,P07602,Q9NZJ7,P17900,P33897,O75381,P06865,P06280 9 +Fever 0.4563515255362657 2.5815681844583525 0.0098352560746257 1.0 0.7457746331090924 79 P07602,P06280,Q9HC07,P03886,P23786,Q9NZJ7,P28070,Q9BW27,P10253,P35610,Q9NR77,Q8NFH4,P10644,Q9NZ08,P00846,Q9ULK5,Q13510,Q14739 18 +Horizontal nystagmus 0.6357027958703576 2.577284558804271 0.009957993560306 1.0 0.7457746331090924 23 P07602,Q9H061,P04062,O95831,P00846,O14773 6 +Muscle stiffness 0.6316763104589901 2.5489018794234473 0.0108062699438469 1.0 0.7457746331090924 22 P07602,Q9NZJ7,P23786,Q9BRK0,P53985,P49748,P11166,P33897,P00846,Q15392 10 +Morphological abnormality of the pyramidal tract 0.6295491324942372 2.537715526498408 0.0111578640508653 1.0 0.7457746331090924 24 Q9Y4P3,P35637,O75298,O00400,Q9Y619,O95831,Q9H9P8,P00846 8 +Abnormal biliary tract morphology 0.6264155680087086 2.5145788135214695 0.0119174662315033 1.0 0.7457746331090924 23 P07602,Q10713,Q14108,Q9NZJ7,P04062,Q5XKP0,Q14739,Q9NSD9 8 +3 methylglutaconic aciduria 0.747259351323719 2.510107919158651 0.0120694269756065 1.0 0.7457746331090924 11 Q9H6K4,Q5XKP0,Q9NVI7 3 +Rhizomelia 0.7215679167902419 2.49942483947403 0.0124395083267789 1.0 0.7457746331090924 13 Q03164,Q15125,Q7RTS9,O75718,Q9BV10,Q14739,Q9UBM7,Q15392 8 +Blindness 0.4603048850462125 2.4898824520458884 0.0127785350880686 1.0 0.7457746331090924 77 P51798,O43676,Q86SQ9,P07602,P53701,O75306,P03886,Q9Y6M9,Q9H6K4,Q86Y39,O43505,Q9NPL8,Q9NZ08,P00846,Q96CU9,P06865,P50897 17 +Abnormal corneal epithelium morphology 0.6929913683087243 2.48159839636715 0.0130794593679595 1.0 0.7457746331090924 15 O75844,Q14739,Q9NZ08,Q96EK5 4 +Progressive visual loss 0.6349052645203341 2.469252866712826 0.013539550455895 1.0 0.7457746331090924 19 P03886,O75503,O14773,P00846,P50897 5 +Variable expressivity 0.4393563382962878 2.4500939299062026 0.0142818952576435 1.0 0.7457746331090924 80 Q8NI60,P00374,Q15125,P07602,P03886,Q9H061,Q70HW3,Q9NR77,O95470,Q13510,Q13509 11 +Disproportionate short stature 0.6127918704835341 2.435998896522752 0.014850729830441 1.0 0.7457746331090924 28 Q03164,Q15125,Q7RTS9,O75718,Q7LGA3,Q96HY6,P10644,Q9BV10,Q14739,Q9UBM7,Q15392,Q9UHX1,O15228 13 +Progressive neurologic deterioration 0.6149423861875323 2.4358419773328936 0.0148571734177684 1.0 0.7457746331090924 22 Q9Y287,P07602,Q10713,Q9NZJ7,P04062,P54802,Q9NPL8,Q5XKP0 8 +Hypocholesterolemia 0.7866219797426509 2.4232345287315726 0.0153829919365735 1.0 0.7457746331090924 9 P07602,Q9NZJ7,Q9BV10,Q9NVI7,Q15800 5 +Disproportionate short limb short stature 0.6126931822751639 2.421093423713063 0.0154738999134433 1.0 0.7457746331090924 23 Q03164,Q15125,Q7RTS9,O75718,Q7LGA3,P10644,Q9BV10,Q14739,Q9UBM7,Q15392 10 +Aortic valve stenosis 0.7836790137993734 2.408891465931986 0.016001055671839 1.0 0.7457746331090924 9 O75844,Q15125 2 +Hypothermia 0.7813629774874609 2.3975864690273356 0.0165034852167549 1.0 0.7457746331090924 9 P49748,Q5XKP0,P00846,P03886 4 +Polyneuropathy 0.6056872992627911 2.373106784599277 0.0176391634600316 1.0 0.7457746331090924 21 P07602,P03886,Q9NZJ7,P04066,O95831,P00846,Q15041 7 +High frequency sensorineural hearing impairment 0.9734714290218524 2.366270355903096 0.0179683176913314 1.0 0.7457746331090924 4 O75844,Q13510 2 +Osteoarthritis 0.7464470806941378 2.3580099801357073 0.0183731989918205 1.0 0.7457746331090924 10 O75844,P04062,Q14108 3 +Dyspnea 0.4255448909019078 2.356955911665937 0.0184254342978547 1.0 0.7457746331090924 97 P35637,P21281,P03886,P04062,Q9Y619,P53701,P00846,P06280,O75306,O75844,P23786,Q92804,O75419,P49748,Q15165,O95831,Q13510,Q96EY8,P07602,P10644,Q9UHX1,Q9NZJ7,P10253,P12235,Q7LG56,Q16134 26 +Optic disc pallor 0.5495966478548797 2.3475008645848856 0.0188998292930073 1.0 0.7457746331090924 54 O75306,Q9Y287,O43676,P51798,Q10713,P03886,Q9Y6M9,Q9H061,Q9H6K4,Q86Y39,Q9NPL8,O95831,P00846,Q96CU9 14 +Abnormal conjunctiva morphology 0.6007175984572549 2.3395446629477386 0.0193072629061816 1.0 0.7457746331090924 24 P28070,P04066,P10619,Q9NZ08,Q14739,Q13510,P06280 7 +Increased cerebral lipofuscin 0.8895800933125865 2.333751675392941 0.0196087285241544 1.0 0.7457746331090924 5 O75503,P07602,P50897,O14773 4 +Abnormality of the mitochondrion 0.4239640316731113 2.3153904456775254 0.0205915739266095 1.0 0.7457746331090924 99 O43676,P35637,P03886,Q9Y2R0,Q70HW3,Q9P0S2,Q9BUB7,P00846,Q96CU9,O75306,P23786,Q86Y39,Q9Y584,P49748,Q99757,Q9NPL8,Q7KZN9,P13073,Q9Y6M9,Q9UBX3,P12235,Q7LG56,Q16134 23 +Peripheral demyelination 0.636936942874579 2.302652199491422 0.0212984196691181 1.0 0.7457746331090924 17 P07602,P03886,Q9NZJ7,Q9NR77,P00846 5 +Dementia 0.5177761611293549 2.286402566265212 0.0222307183440808 1.0 0.7457746331090924 61 Q9Y287,P05067,P35637,O15118,P03886,P04062,P27544,P17900,P00846,P06865,P22626,O96008,Q13510,O76024,Q9Y487,Q9NQZ5,P07602,Q6Y7W6,Q14108,Q9NZJ7,P33897,Q7LG56,P21912 23 +Abnormal circulating cholesterol concentration 0.5846281563558021 2.281400592124648 0.0225247530396677 1.0 0.7457746331090924 35 Q15125,P07602,Q9NZJ7,Q8N511,Q15800,Q9BV10,Q9NVI7,O75845,Q14739,Q9UBM7,Q15392 11 +Hemivertebrae 0.6935268521807569 2.2799607220533185 0.0226100181238226 1.0 0.7457746331090924 12 Q9UHX1,Q15125,P16435,Q9Y619 4 +Unusual infection by anatomical site 0.6930693320931387 2.2774238999934098 0.0227609242355091 1.0 0.7457746331090924 12 Q9NZ08,Q14739,Q8TAA9,Q9H9P8 4 +Anencephaly 0.6452367470035394 2.273739807314737 0.0229816352409433 1.0 0.7457746331090924 16 P21281,Q96J42,O43505,O43175,Q9ULK5,Q8TAA9,P21964 7 +Splenomegaly 0.40944622136604 2.2678425762991825 0.0233388033455719 1.0 0.7457746331090924 86 P21281,O15118,P04062,Q96A33,Q9NZ08,Q15392,Q9BT22,P51798,P00813,P04066,Q14739,Q13510,P07602,Q10713,P28070,P21964,Q14108,Q9NZJ7,P10253,P54802,O00192,P11166 22 +Respiratory distress 0.5466080995727178 2.267185153741717 0.0233789173749008 1.0 0.7457746331090924 52 O75306,Q96EY8,P07602,P21281,P03886,P23786,Q9NZJ7,P04062,P10253,Q9Y619,O75419,P49748,O95831,P53701,P00846,Q16134,Q13510,Q9UHX1 18 +Abnormality of the alveolar ridges 0.8348985733211423 2.265083424623337 0.0235075605869996 1.0 0.7457746331090924 6 P98175,Q15392,O43924,P21281 4 +Abnormality of glycolipid metabolism 0.8070097742888707 2.2626329988401483 0.0236583221831179 1.0 0.7457746331090924 7 P07602,P06280,P06865,Q9NZJ7 4 +Biliary tract abnormality 0.5888591034522775 2.2624703892193776 0.0236683562995676 1.0 0.7457746331090924 27 P07602,O96028,Q10713,Q14108,Q9NZJ7,P04062,Q5XKP0,Q14739,Q9NSD9 9 +Epiphyseal stippling 0.667753305470336 2.262316625712117 0.0236778479471975 1.0 0.7457746331090924 14 Q9Y5Y5,Q15125,P38435,P10644,O75381,Q9UBM7,Q14739 7 +Mitochondrial inheritance 0.8723280828151838 2.2620198805972755 0.0236961750250597 1.0 0.7457746331090924 5 P03886 1 +Abnormality of circulating adrenocorticotropin level 0.8315900443961257 2.250590242065643 0.0244115020256197 1.0 0.7457746331090924 6 Q13423,P10644 2 +Ventricular preexcitation 0.775958754080838 2.2479958825932234 0.0245764524679621 1.0 0.7457746331090924 8 O75306,P00846,P03886 3 +Cherry red spot of the macula 0.7505324721419665 2.245630771113499 0.0247276678157504 1.0 0.7457746331090924 9 P07602,Q9NZJ7,P10619,P17900,Q13510,P06865 6 +Ascites 0.5867978403669145 2.242261500878418 0.0249444764029991 1.0 0.7457746331090924 24 Q14108,O15118,P04062,P10644,Q14739,Q01844,Q13510,Q9NSD9 8 +Ambiguous genitalia 0.5866441385120613 2.2412680388256216 0.0250087179426816 1.0 0.7457746331090924 22 P21281,Q96J42,O43175,O75845,P16435,P53701,Q8TAA9,Q9UBM7,O60566,Q15392 10 +Calcinosis 0.8672272651970898 2.240699538501832 0.0250455440272447 1.0 0.7457746331090924 5 O75844 1 +Lacticaciduria 0.8288023356136899 2.238359794672641 0.0251976016775377 1.0 0.7457746331090924 6 P00846,P03886 2 +Abnormality of the vasculature of the eye 0.4693825096654307 2.237911736188051 0.02522681154557 1.0 0.7457746331090924 71 Q86SQ9,P03886,P10619,P17900,Q9NZ08,P00846,P06865,P06280,O75306,Q9Y4P3,P04066,Q14739,Q13510,Q9C0D9,Q99643,P07602,P28070,P21964,P38435,Q9NZJ7,O00192 21 +Dyschromatopsia 0.8285385537986252 2.23720162338958 0.0252731653149236 1.0 0.7457746331090924 6 Q9H061 1 +Visual loss 0.5514774366656388 2.236693205282843 0.0253063984019572 1.0 0.7457746331090924 49 O75306,P51798,P48449,P07602,Q10713,P03886,O75503,O14773,P53701,P00846,P50897,Q13509 12 +Abnormal placental size 0.938603511993542 2.2310902964965074 0.0256751483834141 1.0 0.7457746331090924 4 O75844 1 +Abnormality of temperature regulation 0.4165139717645291 2.218771567563562 0.0265022692701135 1.0 0.7457746331090924 99 P03886,P35610,Q9NZ08,P00846,P06280,P51798,P00813,P23786,P49748,Q14739,Q13510,P07602,Q9HC07,P28070,P10644,Q9NZJ7,Q9BW27,P10253,Q9NR77,Q8NFH4,Q5XKP0,Q9ULK5 22 +Abnormal circulating citrulline concentration 0.861134684342584 2.2151671002588182 0.0267485971580063 1.0 0.7457746331090924 5 P00846,P03886 2 +Undetectable electroretinogram 0.8586718587563067 2.204825437919353 0.0274663462858835 1.0 0.7457746331090924 5 P50897,O14773 2 +Corneal opacity 0.5361438293380767 2.202105446932415 0.0276578608202988 1.0 0.7457746331090924 53 P56589,P04062,P10619,Q9NVI7,P53701,O60566,P06280,Q9Y4P3,Q9Y5Z9,O75844,P04066,Q96J42,P51648,Q13510,Q9Y2B2,O75845,Q9NX14,Q9UBM7,Q9Y5Y5,O96028,P16278,Q06136,Q6NUK1,O43505,O75381 25 +Progressive psychomotor deterioration 0.7652823190569615 2.196932770315893 0.0280252480177289 1.0 0.7457746331090924 8 P16278,P07602,Q10713,Q9NZJ7 4 +Action tremor 0.5227455606167614 2.1968288726636995 0.0280326701937481 1.0 0.7457746331090924 57 O75306,Q9Y287,P07602,P35637,Q14108,P03886,Q9NZJ7,Q9BRK0,Q9H6K4,O75027,Q9NR77,O14773,P00846,Q99720 14 +Elevated pulmonary artery pressure 0.5935278963395532 2.1959096465772725 0.0280984111375888 1.0 0.7457746331090924 19 O75844,P04062,Q14108,P03886 4 +Reduced visual acuity 0.4235348486379555 2.185139273709522 0.028878636412134 1.0 0.7457746331090924 111 O43676,Q86SQ9,P03886,Q9H061,Q9H6K4,P53701,Q9NZ08,P00846,Q96CU9,P06865,Q13509,P51798,O75306,P50897,Q86Y39,Q9NPL8,P07602,Q10713,Q9Y6M9,Q9UHX1,O43505 21 +Left ventricular systolic dysfunction 0.7891770295198093 2.180912227171609 0.0291899091652447 1.0 0.7457746331090924 7 O75844,Q7LG56,P12235 3 +Slow decrease in visual acuity 0.788106230291899 2.1759807188646603 0.0295567023242895 1.0 0.7457746331090924 7 P00846,P03886 2 +Fluctuations in consciousness 0.7847638398627764 2.1605697277017546 0.0307285919606212 1.0 0.7457746331090924 7 P04062,P03886 2 +Abnormality of the umbilical cord 0.7572131413424547 2.158138822514832 0.0309170401437206 1.0 0.7457746331090924 8 O75844,O43175,P16435 3 +Abnormality of pulmonary circulation 0.5745073452911647 2.1565006137134115 0.0310445959037497 1.0 0.7457746331090924 22 Q14108,P03886,O75844,P04062,Q9NZ08 5 +Abnormal brainstem mri signal intensity 0.5744598784208248 2.156167530571588 0.0310705859202324 1.0 0.7457746331090924 22 O75306,O43676,P03886,Q86Y39,Q9NPL8,O95831,Q96CU9 7 +Decreased activity of mitochondrial complex iv 0.6000607470109646 2.15067939164239 0.0315015140805312 1.0 0.7457746331090924 18 Q9Y584,Q9Y2R0,Q70HW3,Q9P0S2 4 +Increased serum pyruvate 0.5653599508320188 2.144961516764295 0.0319559240050646 1.0 0.7457746331090924 36 O75306,O43676,Q9BWD1,P03886,Q70HW3,Q86Y39,Q9NP80,Q9P0S2,Q9NPL8,P22695,O95831,Q96CU9 12 +Retinal vascular tortuosity 0.624339281595524 2.1449585422772923 0.0319561618475789 1.0 0.7457746331090924 16 Q9Y4P3,O75306,P03886,P00846,Q9C0D9,P21964 6 +Mucosal telangiectasiae 0.7284579083658704 2.1351465048920164 0.0327490449678016 1.0 0.7457746331090924 9 Q14739,P10619,Q99643,P06280 4 +Lower limb hypertonia 0.7022533422180355 2.1283032187111495 0.0333119514178239 1.0 0.7457746331090924 10 O00400 1 +Abnormal pericardium morphology 0.7270570610825574 2.1280876775910444 0.033329814791001 1.0 0.7457746331090924 9 Q9NZ08,P04062,Q14108 3 +Raynaud phenomenon 0.8028388041106779 2.1236285217093434 0.0337012186339502 1.0 0.7457746331090924 6 O75844 1 +Lower limb spasticity 0.3992713665388142 2.123194692863131 0.0337375405148996 1.0 0.7457746331090924 87 P35637,Q9BRK0,Q9H6K4,P04062,Q9Y619,P00846,Q96CU9,O75306,O00400,Q6DKK2,O95831,Q9C0D9,Q99720,P07602,O75298,Q7KZN9,Q9Y5Y5,Q9NZJ7,P11166,Q5XKP0,Q15041 21 +Color vision defect 0.6653283527401863 2.1221959046459387 0.033821290323788 1.0 0.7457746331090924 12 Q9H061 1 +Sensorimotor neuropathy 0.5638893463252708 2.1164675101005157 0.034305065634435 1.0 0.7457746331090924 34 P07602,P03886,Q9NZJ7,Q9Y2R0,P05023,Q9NR77,O95831,Q7LG56,P00846 9 +Abnormal csf protein level 0.6537924476332175 2.116223696023251 0.0343257867914554 1.0 0.7457746331090924 13 P07602,Q9NZJ7,P03886,Q9NR77,Q7LG56 5 +Broad palm 0.800937049526219 2.115166576251699 0.0344157525508577 1.0 0.7457746331090924 6 Q7RTS9,Q14739,P10644,O95831 4 +Adrenal hypoplasia 0.7239467282262131 2.112394547688021 0.0346526222720224 1.0 0.7457746331090924 9 O75844 1 +Fetal ultrasound soft marker 0.5809245467679317 2.1109451017066014 0.0347770308218566 1.0 0.7457746331090924 19 P56589,Q9Y2B2,Q9BPU6,Q15125,Q9Y5Y5,P21281,P61978,P50542,O75381,P16435 10 +Abnormality of corneal stroma 0.6527036463834481 2.109926915471517 0.0348646514845727 1.0 0.7457746331090924 13 Q9Y5Z9,P16278,P04062,P10619,O43505,O75845,Q13510 7 +Hypersplenism 0.7451980328749385 2.1000541047586374 0.0357240819523201 1.0 0.7457746331090924 8 P07602,P04062,Q14108 3 +Abnormal auditory evoked potentials 0.7212392953183001 2.098711515486577 0.0358423389417204 1.0 0.7457746331090924 9 Q15125,P07602,Q9NZJ7 3 +Delusions 0.5915993687390124 2.0950754195488552 0.0361642886191588 1.0 0.7457746331090924 18 P07602,P04062,Q9BQE5,P21964 4 +Abnormality of hepatobiliary system physiology 0.3961325452952575 2.0928300217476186 0.0363643308181051 1.0 0.7457746331090924 86 P03886,O15118,P04062,Q9Y619,Q96A33,Q9P0S2,P00846,Q9BT22,O75306,P23786,Q8N511,Q13510,Q10713,O43772,Q9Y5Y5,Q5XKP0,P22695,O75381,Q9NSD9 19 +Abnormalities of placenta or umbilical cord 0.6152333592384014 2.0882538475397627 0.0367749422721914 1.0 0.7457746331090924 16 Q9Y2B2,P21281,O75844,O43175,Q9H4L7,P16435 6 +Muscle abnormality related to mitochondrial dysfunction 0.5520593265059424 2.0856402165618024 0.0370112255365324 1.0 0.7457746331090924 40 O75306,O43676,P03886,Q9Y6M9,Q9Y2R0,Q9UBX3,Q86Y39,Q9NP80,P12235,Q9NPL8,P00846,Q96CU9 12 +Mania 0.6372705053548454 2.08298770551938 0.0372523442302241 1.0 0.7457746331090924 14 P03886,P12235,P51812,P16615,Q7LG56,P21964 6 +Hyperextensible skin 0.6364600243379845 2.078169805633471 0.0376937220715121 1.0 0.7457746331090924 14 Q9NWM8,Q8NCH0,Q9UHX1 3 +Pulmonary infiltrates 0.7908430057856025 2.0701203507322705 0.0384410755819197 1.0 0.7457746331090924 6 Q13510,P04062 2 +Abnormal lower motor neuron morphology 0.7650578806116255 2.0691635001083397 0.0385307465637527 1.0 0.7457746331090924 7 Q13510,Q99720 2 +Hyperventilation 0.8265716379778192 2.068955028310705 0.0385503070065615 1.0 0.7457746331090924 5 P03886 1 +Limb ataxia 0.5622888168480323 2.068402323125669 0.0386022069498515 1.0 0.7457746331090924 24 Q10713,Q14108,P04062,Q9NR77,O14773,P07196,Q8IV08 7 +Neuronal loss in central nervous system 0.6652321767950548 2.0659338653963006 0.0388347246488709 1.0 0.7457746331090924 11 P07602,P04062,P35637,O15118 4 +Submucous cleft of soft and hard palate 0.5619184727022991 2.0657500598442895 0.0388520858094558 1.0 0.7457746331090924 24 O75844,Q7LGA3,Q9Y619,O43175,O43505,Q15392 6 +Generalized joint laxity 0.6633690681646014 2.0555745664304967 0.0398235414140946 1.0 0.7457746331090924 11 Q8NCH0,Q9UHX1 2 +Pericardial effusion 0.8233318038819764 2.0551313603950843 0.0398663186258336 1.0 0.7457746331090924 5 P04062,Q14108 2 +Cognitive impairment 0.4576431503359101 2.0497152372450405 0.0403922272227723 1.0 0.7457746331090924 174 P56589,Q9Y287,Q86SQ9,P05067,P35637,P03886,O15118,Q9Y2R0,Q9H6K4,Q13217,P04062,P27544,P50542,Q9Y619,P13473,Q9BRK0,O95470,P17900,Q9UHD9,Q9NZ08,P00846,P06865,P50897,P06280,Q8NHS3,O75306,P22626,Q6DKK2,O96008,Q9NPL8,Q9BQE5,O95831,P07196,Q13510,O76024,Q99643,Q99720,Q9NQZ5,Q9Y487,P07602,Q10713,O75503,P10644,Q6Y7W6,P21964,Q9Y5Y5,Q03164,Q14108,P16278,Q9NZJ7,O75381,Q9H2C2,P12235,P54802,P11166,P33897,Q5XKP0,Q9UEY8,Q7LG56,P21912 60 +Abnormal metabolic brain imaging by mrs 0.5583914902956904 2.047810722944758 0.0405785492583818 1.0 0.7457746331090924 20 O75306,P07602,Q9NZJ7,P03886,Q9P0S2 5 +Abnormal circulating long chain fatty acid concentration 0.7338517446951851 2.0448520817484224 0.0408694433028291 1.0 0.7457746331090924 8 P56589,Q9Y5Y5,P23786,P33897,O75381 5 +Erlenmeyer flask deformity of the femurs 0.8893034825870633 2.0366470715186655 0.0416854220891673 1.0 0.7457746331090924 4 P51798,P07602,P04062 3 +Microretrognathia 0.6064666872210953 2.0333241609834216 0.0420197837447939 1.0 0.7457746331090924 16 Q8NCH0,Q15125 2 +Abnormal sensory nerve conduction velocity 0.7567086122210642 2.0301546882499637 0.042340818033151 1.0 0.7457746331090924 7 Q7LG56,Q9NR77 2 +Angina pectoris 0.8869428727473658 2.0272415617844266 0.0426377146177037 1.0 0.7457746331090924 4 O75844 1 +Microcytic anemia 0.7293205819338354 2.0227122569681693 0.0431028224612766 1.0 0.7457746331090924 8 O75027,Q9UBX3 2 +Infectious encephalitis 0.7540856756126185 2.017865721831335 0.0436052478691111 1.0 0.7457746331090924 7 Q9NZ08,Q14739,Q9H9P8 3 +Broad foot 0.7789519634280114 2.016770505752853 0.0437194682296067 1.0 0.7457746331090924 6 O43175,O95831 2 +Impaired proprioception 0.5383155578596845 2.0162240489524725 0.0437765527684925 1.0 0.7457746331090924 43 O00165,Q9BRK0,Q9H6K4,O00400,Q9Y619,P54802,Q9NR77,O14773,P07196,P00846,Q8IV08 11 +Increased intracranial pressure 0.6137580956397899 2.007803017842825 0.044664228033868 1.0 0.7457746331090924 15 Q9NZ08,P07602,P10644,Q99643 4 +Metaphyseal striations 0.8109599740176672 2.0021595513200743 0.0452675744180048 1.0 0.7457746331090924 5 Q9UG56,Q13126 2 +Atrophic scars 0.7743623670892814 1.9960973340340973 0.0459233291740615 1.0 0.7457746331090924 6 Q8NCH0 1 +Spastic paraparesis 0.5519246670757298 1.9949227958410705 0.0460513008466141 1.0 0.7457746331090924 23 Q9Y5Y5,Q13057,Q6DKK2,Q9H6K4,P04062,Q9Y619,O75787,Q5XKP0,P33897,P21912,Q9C0D9 11 +Capillary hemangioma 0.7474586216703915 1.9867439920036352 0.0469507740789212 1.0 0.7457746331090924 7 P21281,Q7LGA3,P16435,Q9UBM7,Q9UHX1 5 +Abnormal activity of mitochondrial respiratory chain 0.4968016936472932 1.9864977413359317 0.0469780833818944 1.0 0.7457746331090924 58 O75306,O43676,P03886,Q9UBX3,Q9Y2R0,Q70HW3,Q86Y39,Q7KZN9,Q9P0S2,Q9Y584,Q9NPL8,P13073,Q96CU9 13 +Abnormality of lysosomal metabolism 0.8067588227306791 1.9841058822171365 0.0472440375312566 1.0 0.7457746331090924 5 P51798,Q13510,P07602 3 +Stillbirth 0.6505061789207035 1.9837262511129832 0.047286365462781 1.0 0.7457746331090924 11 O75844,O43175,P04062,Q14739 4 +Abnormal muscle fiber morphology 0.4413933258899361 1.981194756262189 0.0475694370609691 1.0 0.7457746331090924 72 Q8NI60,O43676,P22626,Q7LG56,P35637,P03886,P23786,O14979,Q70HW3,Q9H2D1,P12235,O96008,O95831,P07196,P00846,Q99720 16 +Abnormal circulating non proteinogenic amino acid concentration 0.7205177540600718 1.9795466612472823 0.0477544915412031 1.0 0.7457746331090924 8 P00846,P03886 2 +Mitochondrial myopathy 0.547464039996619 1.978960360723839 0.0478204693830146 1.0 0.7457746331090924 32 O75306,O43676,P03886,Q9Y6M9,Q86Y39,Q9NP80,P12235,Q9NPL8,P00846,Q96CU9 10 +Morphological abnormality of the corticospinal tract 0.5858904099394752 1.97705991165634 0.0480348584693817 1.0 0.7457746331090924 17 Q9Y4P3,O00400,P35637,P00846 4 +Abnormal placenta morphology 0.7199753881124558 1.976880490345306 0.0480551405911433 1.0 0.7457746331090924 8 O75844 1 +Abnormal saccadic eye movements 0.5495735411146043 1.9768536015604992 0.0480581807697526 1.0 0.7457746331090924 26 P51798,Q10713,P04062,O14773,Q8IV08,Q13509 6 +Pedal edema 0.8046404380533312 1.9749899556404251 0.0482692878829671 1.0 0.7457746331090924 5 P04062,Q14108 2 +Severe lactic acidosis 0.8045409663801175 1.9745616983258476 0.048317909250882 1.0 0.7457746331090924 5 Q70HW3 1 +Abnormal circulating ceruloplasmin concentration 0.8734746826667406 1.9734177878075256 0.04844798266344 1.0 0.7457746331090924 4 O00400 1 +Poor head control 0.4213043640093584 1.969418343473893 0.0489050710097782 1.0 0.7457746331090924 76 O75306,O43676,Q86SQ9,Q9NWM8,P07602,Q10713,P03886,Q9H2C2,Q86Y39,Q9NPL8,P13073,Q5XKP0,Q9Y6M9,Q96CU9,P06865,P00374 16 +Nonprogressive 0.802681383390164 1.9665521976153464 0.049234859040852 1.0 0.7457746331090924 5 Q9NQZ5 1 +Nonketotic hypoglycemia 0.8010245126771312 1.959410376995834 0.0500647463800316 1.0 0.7457746331090924 5 P23786,P31751 2 +Atrophy degeneration involving the corticospinal tracts 0.6058722508728975 1.9592390074706283 0.0500848028986116 1.0 0.7457746331090924 15 Q9Y4P3,O00400,P35637,P00846 4 +Optic neuropathy 0.5467652638248306 1.9565888451298104 0.0503958275527887 1.0 0.7457746331090924 24 O75306,O43676,P03886,Q9Y6M9,Q86Y39,Q9NPL8,P00846,Q96CU9 8 +Depletion of mitochondrial dna in muscle tissue 0.799812327702295 1.95418210689436 0.0506796846206836 1.0 0.7457746331090924 5 P12235,Q9UBX3 2 +Episodic vomiting 0.6257219169640883 1.9524627164441748 0.0508832932952649 1.0 0.7457746331090924 13 P00846,Q9NP80,Q9Y619,P03886 4 +Increased serum lactate 0.4041600682024636 1.9509046848128275 0.0510683852633959 1.0 0.7457746331090924 109 Q99797,P03886,Q70HW3,P35610,O14949,Q9NVI7,Q9BUB7,P00846,Q96CU9,O75306,Q9BWD1,O75208,Q86Y39,Q9NP80,Q9Y584,O95831,Q7KZN9,P13073,Q9Y6M9,Q8NI60,Q9UBX3,P12235,Q5XKP0,P22695,Q7LG56 25 +Duplication involving bones of the feet 0.5446732459106196 1.9474834637421463 0.0514768003586494 1.0 0.7457746331090924 21 Q15125,Q10713,O96028,Q96J42,O43924,O75845,Q14739,Q9UBM7,P21964 9 +Primary adrenal insufficiency 0.5927380486216274 1.9466414991186545 0.051577729689259 1.0 0.7457746331090924 16 P56589,Q9Y5Y5,Q13423,P50542,P33897,O75381,P16435 7 +Underdeveloped supraorbital ridges 0.6142394026405776 1.9450771894986123 0.0517656888117878 1.0 0.7457746331090924 14 P56589,Q9Y5Y5,Q6NUK1,O75381,P98175,P16435 6 +Myoclonic spasms 0.7975548918977726 1.944438302686443 0.0518426187146745 1.0 0.7457746331090924 5 P00846,Q10713,Q99757 3 +Abnormal circulating pyruvate family amino acid concentration 0.5450096120221779 1.9438609988727904 0.0519122155030122 1.0 0.7457746331090924 24 Q99797,O75208,P03886,Q9NP80,Q9P0S2,Q5XKP0,P22695,Q7LG56,P00846 9 +Progressive gait ataxia 0.666906662062609 1.940146957418807 0.0523618326418509 1.0 0.7457746331090924 10 P00846,P07602,O14773 3 +Widened cerebral subarachnoid space 0.8645489110020395 1.9375976442767555 0.0526723301080167 1.0 0.7457746331090924 4 P03886 1 +Centrocecal scotoma 0.8643865254213953 1.936944883804979 0.0527520810833119 1.0 0.7457746331090924 4 P00846,P03886 2 +Abnormality of the cerebrospinal fluid 0.4245925631425884 1.933991112077439 0.0531142206368291 1.0 0.7457746331090924 138 O43676,Q15125,P03886,P04062,P53701,P00846,Q96CU9,Q15392,Q8TAA9,Q13509,P51798,O75306,P23786,Q86Y39,Q96J42,Q99757,Q9NPL8,O95831,P07602,Q10713,Q7KZN9,P13073,P10644,Q9Y6M9,P16435,Q9UBM7,P21964,Q8NI60,O96028,Q9NZJ7,O00192,Q9NR77,O43505,Q7LG56,Q9ULK5,Q9H490 36 +Generalized hyperkeratosis 0.7945434845235797 1.9314254476892525 0.0534304606608149 1.0 0.7457746331090924 5 O75844,P04066,Q99643 3 +Bifid scrotum 0.7944462372612758 1.931004945317016 0.0534824408527001 1.0 0.7457746331090924 5 Q9UBM7,P16435,Q96EK5 3 +Biliary tract neoplasm 0.8624345800335731 1.9290953974560616 0.053719020280943 1.0 0.7457746331090924 4 P07602 1 +Neoplasm of the gallbladder 0.8624345800335731 1.9290953974560616 0.053719020280943 1.0 0.7457746331090924 4 P07602 1 +Progressive spastic quadriplegia 0.7351106565819487 1.9284799217240096 0.0537954593002125 1.0 0.7457746331090924 7 P07602,Q9NZJ7 2 +Very long chain fatty acid accumulation 0.6646847949328801 1.9281890232215335 0.0538316190333578 1.0 0.7457746331090924 10 P56589,Q9Y5Y5,P33897,O75381 4 +Paraplegia paraparesis 0.3812262933023325 1.92750427181834 0.0539168162026999 1.0 0.7457746331090924 83 P56589,P35637,Q9BRK0,Q9H6K4,P04062,Q9Y619,P00846,Q96CU9,O75306,O00400,Q6DKK2,O95831,Q13510,Q9C0D9,O75298,Q7KZN9,P42356,Q9Y5Y5,O75251,P11166,P33897,Q5XKP0,Q15041 23 +Phenotypic variability 0.3984038855722665 1.9267888415745689 0.0540059506506527 1.0 0.7457746331090924 104 Q8NI60,P00374,Q86SQ9,Q15125,P07602,P03886,O14979,Q9H061,Q70HW3,Q9NR77,O95470,P00846,Q13510,Q13509 14 +Segmental peripheral demyelination remyelination 0.7589245006446924 1.9262293264999344 0.0540757455217941 1.0 0.7457746331090924 6 P00846,Q9NR77,P03886 3 +Supernumerary tooth 0.7344797483109984 1.9254933925357256 0.0541676617971853 1.0 0.7457746331090924 7 Q9Y2B2,P21281,Q9UHX1 3 +Blurred vision 0.7923331588220264 1.921863586735016 0.0546229247141505 1.0 0.7457746331090924 5 P00846,P03886 2 +Nephropathy 0.5417715472107762 1.921772334034598 0.0546344109461134 1.0 0.7457746331090924 23 Q10713,P06280,Q14108,P03886 4 +Cerebral white matter atrophy 0.5401603992221978 1.918802396468812 0.0550093464653389 1.0 0.7457746331090924 20 Q9H9P8,O75503,O43175 3 +Impaired vibration sensation in the lower limbs 0.5649925680900376 1.918010838185944 0.0551096368931873 1.0 0.7457746331090924 18 Q9BRK0,Q9NR77,P00846,O00400 4 +Abnormal form of the vertebral bodies 0.3810841455920162 1.9141977803658152 0.0555948892735249 1.0 0.7457746331090924 84 Q15125,P21281,Q9Y619,Q8TAA9,P51798,Q9Y4P3,P00813,P04066,Q9BV10,O95831,Q14739,Q10713,Q7RTS9,P51812,P10644,O75845,P16435,Q9UBM7,Q9UHX1,O96028,P54802,Q9ULK5 22 +Atlantoaxial abnormality 0.7905183280862069 1.9140059342630875 0.0556193975087737 1.0 0.7457746331090924 5 Q9NWM8,Q8NCH0 2 +Central apnea 0.7067741645745064 1.9117502722052775 0.0559082328281346 1.0 0.7457746331090924 8 P07602,O76024,Q10713,Q9NZJ7 4 +Mitral stenosis 0.8571103337616786 1.9076564485748768 0.0564356341175042 1.0 0.7457746331090924 4 O75844 1 +Abnormal circulating proteinogenic amino acid derivative concentration 0.5400869282259603 1.9073050472371171 0.0564810970008224 1.0 0.7457746331090924 25 Q99797,O75208,P03886,Q9NP80,Q9P0S2,Q5XKP0,P22695,Q7LG56,P00846 9 +Contractures of the joints of the upper limbs 0.4391846174328701 1.9061719382203344 0.0566279017437614 1.0 0.7457746331090924 71 Q9Y2B2,P42892,P50402,P35637,O75844,P23786,Q7LGA3,Q9Y619,O75419,Q99720,Q9NR77,O43175,Q8IZA0,Q9BUB7,P07196,P16435,Q15392,Q13509 18 +Hydrocele testis 0.8564957412038873 1.9051790491683256 0.0567568006132583 1.0 0.7457746331090924 4 Q9NVI7,Q9UBX3 2 +Neurofibrillary tangles 0.7878229525728403 1.9023246886073424 0.0571287199799042 1.0 0.7457746331090924 5 Q9Y287,O96008,O15118 3 +Foam cells 0.7528247122658543 1.8984842919547231 0.0576323150808584 1.0 0.7463849697934495 6 Q13510,O75845,P16278,O15118 4 +Abnormality of skull ossification 0.6253326690460782 1.8935104055734595 0.0582900257554948 1.0 0.7463849697934495 12 O75844,O75718,P54802,Q9HC21,Q14739 5 +Anteriorly placed anus 0.6335984868764287 1.8884193947574492 0.0589696696528159 1.0 0.7463849697934495 11 Q9Y2B2,P53701,Q6NUK1,P49748,P48651,Q9NX14,P16435 7 +Anorexia 0.5367633753832504 1.8829422097786472 0.0597082001195279 1.0 0.7463849697934495 25 Q13423,Q14108,P04062,P35610,P10644,Q9NZ08,Q5HYI8,P06280 8 +Mitochondrial respiratory chain defects 0.7488895258547525 1.880543762920066 0.0600340079034655 1.0 0.7463849697934495 6 O75306,P00846,P03886 3 +Bilateral talipes equinovarus 0.8494211991010663 1.876622868104305 0.060569800857563 1.0 0.7463849697934495 4 Q15125 1 +Hyperactive patellar reflex 0.6996233452804329 1.8762832266571503 0.0606163990212236 1.0 0.7463849697934495 8 P21912,Q5T440,Q15041,P13073 4 +Abnormal social behavior 0.4446331600330281 1.8718529885399433 0.0612269450454401 1.0 0.7463849697934495 69 O75306,O43676,Q9Y4P3,Q15125,P07602,P03886,Q9NZJ7,Q15067,Q86Y39,Q9NPL8,Q5XKP0,Q9Y6M9,Q15907,Q96CU9,Q9UHX1,Q13509 16 +Unilateral renal agenesis 0.5332324098157628 1.869320308775277 0.0615782642858377 1.0 0.7463849697934495 20 Q86XL3,Q7LGA3,P10644,P16435,Q9UHX1 5 +Abdominal pain 0.3823393804250494 1.869188770172241 0.0615965560836104 1.0 0.7463849697934495 82 Q13423,P42892,Q7LG56,Q14108,P35637,P23786,Q9BW27,Q70HW3,P04062,Q8NFH4,P10644,Q9NZ08,Q5HYI8,Q99643,P06280 15 +Abnormal circulating carbohydrate concentration 0.523325282866971 1.8666142643583576 0.0619554741637409 1.0 0.7463849697934495 41 O75306,O43676,Q9BWD1,P03886,Q70HW3,Q86Y39,Q9NP80,Q9P0S2,Q9NPL8,P22695,O95831,Q96CU9 12 +Loss of speech 0.5447347135857804 1.8625477488877584 0.062525921555455 1.0 0.7463849697934495 19 P07602,Q9NZJ7,O15118,P17900,P50897 5 +Emphysema 0.6963957385291475 1.8602320562897217 0.062852701539747 1.0 0.7463849697934495 8 Q03518,P06280 2 +Focal t2 hyperintense brainstem lesion 0.5440392557772206 1.8577107224574465 0.063210105013999 1.0 0.7463849697934495 19 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q96CU9 6 +Acquired abnormal hair pattern 0.7438348612772145 1.8574524732844295 0.0632468069264295 1.0 0.7463849697934495 6 O75844,P11166 2 +Demyelinating peripheral neuropathy 0.5548457540080372 1.8496076688687544 0.0643701167031971 1.0 0.7463849697934495 18 P07196,P03886,Q9NR77,Q7LG56,P00846 5 +Abnormal mitochondria in muscle tissue 0.5313731422855329 1.8488332323100711 0.0644818971123608 1.0 0.7463849697934495 22 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q96CU9 6 +Macular degeneration 0.5981345027445182 1.84741747339065 0.0646866586752368 1.0 0.7463849697934495 14 Q13510,P04062,P50897 3 +Bilateral tonic clonic seizure with generalized onset 0.6720378168697323 1.8464028763399607 0.0648337298971151 1.0 0.7463849697934495 9 P11166,Q13510,P04062 3 +Airway obstruction 0.6075005392410857 1.8445905675552736 0.0650971201501768 1.0 0.7463849697934495 13 O75844,O00192,Q96HY6,P16435,P21964,P06280 6 +Pathologic fracture 0.5764226728394117 1.8425850750047843 0.0653896146880717 1.0 0.7463849697934495 16 P22626,Q14108,P04062,O15269,Q13126 5 +Corneal ulceration 0.7729713353175416 1.837725425399487 0.0661028753508579 1.0 0.7463849697934495 5 O75844 1 +Abnormal larynx morphology 0.5305960334331894 1.8374183395463624 0.0661481614808958 1.0 0.7463849697934495 27 P21964,P07602,Q9NZJ7,O00192,Q14739,Q13510,P16435,Q9UHX1 8 +Corpus callosum atrophy 0.5855324775095858 1.8328172155367952 0.0668297580961818 1.0 0.746851055398336 15 O75503,Q9H9P8 2 +Prolonged partial thromboplastin time 0.770671371778257 1.8276862992007952 0.0675966455250351 1.0 0.746851055398336 5 Q9BV10 1 +Laryngomalacia 0.6137837054840262 1.8264169995282935 0.0677874731489514 1.0 0.746851055398336 12 P07602,P16435,P21964,Q9NZJ7 4 +Abnormal circulating fatty acid concentration 0.5275577223702858 1.818444052045656 0.0689962905551924 1.0 0.746851055398336 23 P56589,Q9Y5Y5,P23786,Q9P0S2,P49748,O43772,O75431,P33897,O75381 9 +Abnormal morphology of the conjunctival vasculature 0.7115625562519136 1.8163893623051115 0.0693106658398743 1.0 0.746851055398336 7 P10619,P06280 2 +Hypocalcemia 0.5722405674521229 1.8157327733977535 0.0694113741075517 1.0 0.746851055398336 16 P51798,O00192,P49748,P10644,Q9BV10,P21964,Q9NSD9 7 +Upper airway obstruction 0.8340548407747337 1.814354956935751 0.0696230956566559 1.0 0.746851055398336 4 O75844,P16435 2 +Epispadias 0.7670295489890965 1.8117711402766896 0.0700215661234233 1.0 0.746851055398336 5 Q9NX14,P53701,Q9Y619,O75419 4 +Degeneration of the lateral corticospinal tracts 0.7098821318653212 1.8083423131042349 0.0705532401847928 1.0 0.746851055398336 7 O00400,P35637 2 +Lower limb hyperreflexia 0.5246337439330281 1.8075600667134444 0.0706749980938499 1.0 0.746851055398336 20 Q5T440,O00400,P21912,P13073,Q14739,Q15041,Q9C0D9 7 +Fibrous tissue neoplasm 0.5703427067273958 1.8035231706137216 0.0713060898697215 1.0 0.746851055398336 16 Q15392,P10644,Q99643,Q13126 4 +Toe walking 0.5247298452987927 1.80057215262131 0.0717703416557884 1.0 0.746851055398336 22 P07602,P35637,Q9NZJ7,Q9NP80,O95831,Q99720 6 +Abnormal macrophage morphology 0.7635855223494565 1.7966991825693166 0.0723833888113656 1.0 0.746851055398336 5 Q13510 1 +Abnormal middle phalanx morphology of the hand 0.7304451506076041 1.796031976958259 0.0724894315599611 1.0 0.746851055398336 6 P48651,Q03164,Q9UHX1 3 +Abnormal brain lactate level by mrs 0.5986915424819528 1.7920056479898234 0.0731320612894466 1.0 0.746851055398336 13 Q9P0S2,P03886 2 +Premature rupture of membranes 0.729241599469397 1.7904934385661038 0.0733746211310772 1.0 0.746851055398336 6 O75844 1 +Abnormal retinal vascular morphology 0.4926947564761446 1.790244370824177 0.0734146348817157 1.0 0.746851055398336 52 O75306,Q86SQ9,Q9Y4P3,Q99643,P07602,P21964,P38435,P03886,Q9NZJ7,P16278,O00192,Q15555,P10619,P17900,P00846,Q13510,Q9C0D9,P06865 18 +Resting tremor 0.5341944221167682 1.7889861571740482 0.0736170449442172 1.0 0.746851055398336 19 P07602,Q9NZJ7,Q9H6K4,P04062,P12235 5 +Abnormal light and dark adapted electroretinogram 0.7055324141241706 1.7874836163604115 0.0738593577988171 1.0 0.746851055398336 7 P00846,Q15067,P50897 3 +Abnormal full field electroretinogram 0.7055324141241706 1.7874836163604115 0.0738593577988171 1.0 0.746851055398336 7 P00846,Q15067,P50897 3 +Thickened nuchal skin fold 0.5979253188097434 1.7874185039211457 0.0738698731227125 1.0 0.746851055398336 13 P56589,Q9Y5Y5,Q15125,P21281,P50542,O75381 6 +Multiple lipomas 0.7283686635361797 1.7864745328595917 0.0740224571296488 1.0 0.746851055398336 6 Q9ULK5 1 +Fatigue 0.3962799503094357 1.7838153530742464 0.0744536739645438 1.0 0.746851055398336 78 Q13423,P07602,Q7LG56,P35637,Q9NZJ7,Q92804,Q9H3L0,Q70HW3,P04062,Q9NP80,P12235,P10644,Q15165,Q9NZ08,Q14739,Q5HYI8,Q99643,P06280 18 +Corneal dystrophy 0.759574099831046 1.7791184485934777 0.0752203447116697 1.0 0.746851055398336 5 P12235,P06280 2 +Abnormal foot bone ossification 0.8250842147935051 1.7778554679868048 0.0754275957135102 1.0 0.746851055398336 4 Q15125 1 +Hand polydactyly 0.521198319561198 1.7778529493127193 0.0754280094849482 1.0 0.746851055398336 32 P21964,Q15125,Q10713,O96028,Q15067,Q96J42,O43924,O75845,Q14739,Q9UBM7,P98175,Q9UHX1 12 +Global brain atrophy 0.5212524256481637 1.7752190995904686 0.0758617172587685 1.0 0.746851055398336 22 O75306,P07602,P35637,Q9NZJ7,Q9H9P8,Q9UHX1 6 +Recurrent aspiration pneumonia 0.7255585335026855 1.7735267391882807 0.076141465146428 1.0 0.746851055398336 6 Q13510 1 +Cardiac valve calcification 0.82389147657652 1.772994469876922 0.0762296232357644 1.0 0.746851055398336 4 O75844 1 +Mitral valve calcification 0.82389147657652 1.772994469876922 0.0762296232357644 1.0 0.746851055398336 4 O75844 1 +Endocarditis 0.8234525389579699 1.7712051149478196 0.0765265990063159 1.0 0.746851055398336 4 Q9NZ08,P04062 2 +Supranuclear gaze palsy 0.5311280796807222 1.7674853815088682 0.0771469750774278 1.0 0.746851055398336 19 P07602,P35637,O15118,P04062,Q99720 5 +Ectopic calcification 0.4736669589553061 1.7657526238237975 0.0774373599001914 1.0 0.746851055398336 58 P56589,Q15125,P05067,P03886,P04062,P50542,O75844,P23786,O75431,Q14739,O15228,P10644,O75845,Q9UBM7,Q9Y5Y5,P38435,P11166,O43175,O75381,Q9NSD9 20 +Patchy changes of bone mineral density 0.9615412843803816 1.7644497448585137 0.0776562893180639 1.0 0.746851055398336 3 Q13126 1 +Thickened skin 0.3845979750390265 1.7624600583281085 0.0779915990854345 1.0 0.746851055398336 102 P56589,Q15125,P48449,P98194,P04062,O95470,P31751,P06280,P00813,O75844,P04066,O15269,Q15555,P51648,O75431,Q14739,Q15800,Q99643,Q9Y2B2,Q9NWM8,Q14691,P28070,P16615,Q9Y5Y5,P50402,P16278,P42167,Q06136,O75381,P42166,O43175,Q9H4L7,P21912 33 +Abnormality of the wrist 0.5187974958661875 1.759276374351229 0.0785305774258837 1.0 0.746851055398336 32 Q15125,O75844,Q7RTS9,Q9H6K4,Q9BV10,O95831,Q13510,Q13509 8 +Focal segmental glomerulosclerosis 0.5189611800020958 1.7584803395605546 0.0786658139204106 1.0 0.746851055398336 22 Q14108,P03886,Q9BW27,Q8NFH4,O95470,O75431,Q8N1F7 7 +Stroke like episode 0.7215179500783506 1.7548823553551007 0.0792794328618458 1.0 0.746851055398336 6 P03886 1 +Paraparesis 0.5183522832698827 1.7494823980171716 0.0802076688092026 1.0 0.746851055398336 30 Q9Y5Y5,P35637,Q13057,Q6DKK2,Q9H6K4,P04062,Q9Y619,P42356,O75787,Q5XKP0,P33897,P21912,Q13510,Q9C0D9 14 +Impaired vibratory sensation 0.5160873417022899 1.7475993411675528 0.0805334295161908 1.0 0.746851055398336 34 O00165,Q9BRK0,O00400,Q9Y619,Q9NR77,O14773,P07196,P00846 8 +Polyhydramnios 0.4924901773924486 1.746287622587475 0.0807609855429682 1.0 0.746851055398336 50 P51798,Q15125,P21281,O75844,Q70HW3,P04062,O00192,O43175,Q9NVI7,Q9BV10,Q14739,Q9ULK5,Q9UBM7,P21964 14 +Vomiting 0.3768909481079269 1.745118079651565 0.0809643170812306 1.0 0.746851055398336 94 O43676,P03886,Q9Y619,P35610,P11117,P00846,Q96CU9,P06280,O75306,Q13423,P23786,Q86Y39,Q9NP80,Q9Y584,P49748,Q9NPL8,Q96EY8,P07602,P51571,Q9Y6M9,Q9NZJ7,O43175,P22695,Q7LG56,Q16134,Q9NSD9 26 +Arteriosclerosis 0.5612076370456281 1.744547495546819 0.0810636670374227 1.0 0.746851055398336 16 O75844,Q13510,O15118 3 +Dermal atrophy 0.5180089180744458 1.743391351165085 0.0812652780227409 1.0 0.746851055398336 26 Q9NWM8,O75844,Q8NCH0,P53701,Q15392 5 +Abnormal peripheral myelination 0.5151014462257263 1.7398523617045298 0.081884945412066 1.0 0.746851055398336 34 P07602,Q9NZJ7,P03886,O15269,Q9NR77,Q7LG56,P00846 7 +Vascular tortuosity 0.8155329857889672 1.7388779716108798 0.0820562297321438 1.0 0.746851055398336 4 P03886 1 +Abnormality of circulating leptin level 0.7502983321609342 1.738361665386552 0.0821471069445032 1.0 0.746851055398336 5 O75844 1 +Abnormality of extrapyramidal motor function 0.39242504933858 1.7354098779241554 0.0826682317030849 1.0 0.746851055398336 78 Q86SQ9,P05067,P35637,Q9H6K4,P04062,P35610,P17900,O14949,P06865,Q9Y4P3,Q6DKK2,O96008,Q9H9P8,P98175,Q99720,P07602,Q13057,O75787,Q6Y7W6,O75251,P16278,Q9NZJ7,P12235,P11166,Q96IX5,Q7LG56 26 +Left ventricular hypertrophy 0.5169607645104641 1.7352544988416791 0.0826957372467405 1.0 0.746851055398336 27 O75208,P03886,Q15233,P10253,P12235,Q6NUK1,Q9P0S2,O75787,O75431,P00403,Q7LG56,P21912,P13807,P06280 14 +Mandibular aplasia 0.8143656716417885 1.7341063255077658 0.082899219388334 1.0 0.746851055398336 4 P53701,Q9Y619,O75419 3 +Small placenta 0.9531106594137648 1.7331946219353762 0.0830610826056887 1.0 0.746851055398336 3 O75844 1 +Short umbilical cord 0.9531106594137648 1.7331946219353762 0.0830610826056887 1.0 0.746851055398336 3 O75844 1 +Thin ribs 0.5884106536905971 1.7302833327939549 0.0835796659087491 1.0 0.746851055398336 13 O75844,O95831 2 +Transposition of the great arteries 0.7479603583070753 1.728066281451643 0.0839763418450312 1.0 0.746851055398336 5 O75844,O43175 2 +Talipes calcaneovalgus 0.8127037969877646 1.727310116833211 0.0841119832316024 1.0 0.746851055398336 4 P07196,Q9NR77 2 +Abnormal vertebral morphology 0.3850718205499591 1.7260669275231455 0.0843353728756572 1.0 0.746851055398336 106 Q15125,P21281,P04062,Q9Y619,P10619,Q8TAA9,P51798,Q9Y4P3,P00813,Q8NCH0,P04066,Q9BV10,O95831,Q14739,Q10713,Q7RTS9,P51812,P10644,O75845,P16435,Q9UBM7,Q9UHX1,O96028,Q14108,P54802,Q96HY6,Q9ULK5 27 +Visual field defect 0.5033427327607438 1.7260510572211798 0.0843382277230431 1.0 0.746851055398336 43 P56589,Q9Y287,O75306,Q8NHS3,Q5T440,Q9Y5Y5,P03886,Q9H061,Q9H6K4,O75381,P50542,Q15555,Q9BVA1,P00846 14 +Ureteral duplication 0.7152728087790671 1.7260031258709907 0.0843468503834588 1.0 0.746851055398336 6 P23786,O75844,Q8TAA9 3 +Abnormal enchondral ossification 0.5138960321701368 1.721252215618013 0.08520506640238 1.0 0.746851055398336 32 P56589,Q9Y5Y5,Q15125,O96028,P38435,Q7RTS9,O75381,P50542,Q9Y619,Q96HY6,P10644,Q14739,Q9UBM7,Q9NUQ7,Q9UG56 15 +Thoracic kyphosis 0.557408920474861 1.719923552948091 0.0854463385794803 1.0 0.746851055398336 16 P51648,P04062,Q9UHX1,O95831 4 +Barrel shaped chest 0.7460951369462114 1.7198462735700937 0.0854603887387495 1.0 0.746851055398336 5 Q14739,P04066 2 +Abnormal echocardiogram 0.7457639573693211 1.7183861775105862 0.0857261998714922 1.0 0.746851055398336 5 Q7LG56,P12235 2 +Abnormal endocardium morphology 0.5770767917123232 1.7182422525294558 0.0857524376153073 1.0 0.746851055398336 14 Q9NZ08,P04062,P10644,P06280 4 +Corneal erosion 0.8104852294228349 1.7182319786398066 0.0857543108092149 1.0 0.746851055398336 4 Q96EK5 1 +Eeg with spike wave complexes 0.5560151585291849 1.7108744570541274 0.0871042908246295 1.0 0.746851055398336 16 Q9Y2B2,Q9NQZ5,Q14108,O75503,P11166 5 +Unexplained fevers 0.7118092376228278 1.7099544218486764 0.0872743016092583 1.0 0.746851055398336 6 P07602,Q9HC07 2 +Schizophrenia 0.5109623960012818 1.7085916396905907 0.0875266183592922 1.0 0.746851055398336 20 P07602,O15047,Q9NZJ7,P04062,Q9BQE5,P16615,O76024,P21964 8 +Cns demyelination 0.5657929571983045 1.7085605952216691 0.0875323730375312 1.0 0.746851055398336 15 Q9H9P8,Q15067,P07602,P51648 4 +Aortic valve calcification 0.9454112927602146 1.7046020755398383 0.0882686640113783 1.0 0.746851055398336 3 O75844 1 +Cardiovascular calcification 0.665308542022315 1.7043055940701957 0.0883240104290863 1.0 0.746851055398336 8 O75844 1 +Hypopigmentation of the fundus 0.8068585236427223 1.7033788899464035 0.0884971856398881 1.0 0.746851055398336 4 Q9Y619 1 +Abnormality of fundus pigmentation 0.8068585236427223 1.7033788899464035 0.0884971856398881 1.0 0.746851055398336 4 Q9Y619 1 +Decerebrate rigidity 0.8068517748895946 1.7033512356902052 0.0885023576531556 1.0 0.746851055398336 4 P07602,Q9NZJ7 2 +Trismus 0.8067228172031051 1.7028227973065544 0.0886012352003848 1.0 0.746851055398336 4 O43175 1 +Abnormality of krebs cycle metabolism 0.710029517386566 1.7016991342141463 0.0888117828086514 1.0 0.746851055398336 6 P00846,Q96EY8,P03886 3 +Bone fracture 0.709915947583991 1.7011721350115832 0.0889106686527889 1.0 0.746851055398336 6 Q13126 1 +Aplasia hypoplasia involving the vertebral column 0.5438581106316708 1.7002194563842377 0.0890896538756984 1.0 0.746851055398336 17 Q7RTS9,P04066,O95831,Q14739,Q9ULK5,Q8TAA9 6 +Abnormality of the distal phalanges of the toes 0.7401246069040155 1.6934964405511774 0.0903610118198074 1.0 0.746851055398336 5 O75844,Q7LGA3,O75431 3 +Abnormal speech prosody 0.6631357201432116 1.6933197002475775 0.0903946302571601 1.0 0.746851055398336 8 P00846,P03886 2 +Abnormality of upper limb joint 0.3888140716103606 1.6928013029795956 0.0904932945999053 1.0 0.746851055398336 114 P42892,Q15125,Q9H6K4,Q9Y619,Q9BUB7,Q15392,Q13509,Q9Y4P3,O75844,P23786,Q7LGA3,O75419,Q8IZA0,Q9BV10,O95831,P07196,Q13510,Q9Y2B2,Q7RTS9,P10644,P16435,Q03164,P50402,O96028,Q9NR77,O43175 26 +Elevated hepatic transaminase 0.3833691792346985 1.6923041596982429 0.0905879951273094 1.0 0.746851055398336 107 Q86SQ9,Q9Y619,Q9P0S2,P23786,Q8N511,P49748,Q9BV10,Q14739,Q5HYI8,Q13510,Q10713,Q9HC07,P28070,Q15067,O43772,Q9Y5Y5,P10253,P12235,Q5XKP0,P22695,Q7LG56,Q9NSD9 22 +Enlarged ovaries 0.8041044776119382 1.6920891334526251 0.0906289800393072 1.0 0.746851055398336 4 P16435,P10644,Q99643 3 +Periventricular white matter hyperintensities 0.5991230963631253 1.6911125931900015 0.0908153004746226 1.0 0.746851055398336 11 O75503,P07602,Q9C0D9,Q9NZJ7 4 +Chronic fatigue 0.6852788541995773 1.68981653999264 0.0910630584776044 1.0 0.746851055398336 7 Q13423,Q5HYI8,P07602 3 +Episodic respiratory distress 0.9411305879858508 1.6886860696319148 0.0912796066080319 1.0 0.746851055398336 3 P03886 1 +Limited wrist movement 0.7069035819383525 1.6871850207326655 0.0915677807703099 1.0 0.746851055398336 6 Q9H6K4 1 +Bilateral cryptorchidism 0.6200761806256199 1.6849387339961597 0.0920003924449042 1.0 0.746851055398336 10 O43924 1 +Vegetative state 0.8021697534212545 1.6841526445275612 0.0921521724623246 1.0 0.746851055398336 4 P07602,Q9NZJ7 2 +Hypoplastic vertebral bodies 0.7051089925323742 1.67884431077951 0.0931823902442823 1.0 0.746851055398336 6 Q14739,Q8TAA9,P10644 3 +Abnormal cardiac ventricular function 0.5185472912256148 1.6788061341490674 0.0931898327318507 1.0 0.746851055398336 19 P03886,O75844,P10253,P12235,Q7LG56 5 +Abnormal left ventricle morphology 0.5086118970646396 1.677003741083723 0.0935417502922992 1.0 0.746851055398336 31 O75208,P03886,P10253,P12235,Q6NUK1,Q9P0S2,O75431,Q7LG56,P21912,O60566,P06280 11 +Glomerulopathy 0.6397152465720013 1.6769986148632894 0.0935427527060095 1.0 0.746851055398336 9 Q9NZ08,Q14108 2 +Posterior embryotoxon 0.5078107152619793 1.676642454763377 0.0936124196157619 1.0 0.746851055398336 22 P56589,Q9Y4P3,Q9Y5Y5,Q9NX14,Q7LGA3,O00192,P53701,O75381,P21964 9 +Oromandibular dystonia 0.8002120049887981 1.6761172191004754 0.0937152345927463 1.0 0.746851055398336 4 Q99720 1 +Abnormality of alkaline phosphatase level 0.5085689620892506 1.6739180654284815 0.0941467032326961 1.0 0.746851055398336 25 P51798,Q9Y2B2,P22626,Q92643,Q8N511,Q96A33,Q96AY3,O75845,Q14739,P38571,O96017 11 +Saccadic smooth pursuit 0.7356712636036375 1.6738055594774943 0.0941688193820713 1.0 0.746851055398336 5 Q10713 1 +Amyotrophic lateral sclerosis 0.5500936034804523 1.6723425626323911 0.0944567912070692 1.0 0.746851055398336 16 Q92804,P22626,P35637,Q99720 4 +Foot acroosteolysis 0.7352142048825965 1.6717828756241386 0.0945671447806337 1.0 0.746851055398336 5 O75844 1 +Osteolysis involving bones of the feet 0.7352142048825965 1.6717828756241386 0.0945671447806337 1.0 0.746851055398336 5 O75844 1 +Aplasia hypoplasia involving bones of the thorax 0.503007560529114 1.67046810780306 0.0948267842309467 1.0 0.746851055398336 38 Q9Y2B2,Q03164,P21281,O75844,Q7RTS9,Q9Y619,O75419,Q96HY6,Q9BV10,P16435,Q14739,P98175,O60566,Q8TAA9,Q9UHX1 15 +Congenital ichthyosiform erythroderma 0.7032045171125083 1.669986394698577 0.0949220554581706 1.0 0.746851055398336 6 Q15125 1 +Paroxysmal involuntary eye movements 0.5060055657332173 1.6675738874475072 0.0954003455042376 1.0 0.746851055398336 21 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q96CU9 6 +Proximal tubulopathy 0.5076914418268957 1.667346693334461 0.0954454869823893 1.0 0.746851055398336 25 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q9Y6M9,Q16134,Q96CU9 8 +Polar cataract 0.797885572139301 1.6665627549919553 0.095601380008067 1.0 0.746851055398336 4 Q9Y287,P08670,Q7LGA3 3 +Abnormal midbrain morphology 0.6803945193657472 1.6661331828121189 0.0956868906356203 1.0 0.746851055398336 7 Q10713,P04062 2 +Abnormal lung lobation 0.586491121261437 1.6660408500204118 0.0957052783919518 1.0 0.746851055398336 12 P21964,O00192,Q14739,Q9UBM7,Q9UHX1 5 +Abnormal pulmonary valve morphology 0.5590065908793557 1.6654968569196242 0.0958136701764145 1.0 0.746851055398336 15 P51798,Q9Y2B2,P10644,Q9BUB7,P21964 5 +Abnormal visual fixation 0.6799939085633934 1.6641885056243444 0.0960747643778796 1.0 0.746851055398336 7 Q13510 1 +Macrogyria 0.7016830975334062 1.6629053434982 0.0963313846123137 1.0 0.746851055398336 6 O43175,Q15392 2 +Neck flexor weakness 0.7324361120372704 1.6594816572759994 0.0970187738283279 1.0 0.746851055398336 5 P35637,Q99720 2 +Postaxial foot polydactyly 0.6151069478774396 1.657480035093155 0.0974224620305117 1.0 0.746851055398336 10 Q10713,Q96J42,O75845,Q14739,O43924 5 +Abnormality of the 5th toe 0.6151069478774396 1.657480035093155 0.0974224620305117 1.0 0.746851055398336 10 Q10713,Q96J42,O75845,Q14739,O43924 5 +Abnormality of epiphysis morphology 0.44642823191521 1.6526074112660307 0.0984107887685254 1.0 0.7519045048217273 63 P56589,Q15125,P50542,Q9Y619,P51798,Q5JRA6,Q7LGA3,O75419,O95831,Q14739,O15228,Q9Y2B2,Q9HC07,Q7RTS9,P51812,P10644,Q9UBM7,P16435,Q9Y5Y5,O96028,P38435,P16278,Q96HY6,O75381,Q9NUQ7,Q9UG56 26 +Punctate cataract 0.7938107403375618 1.6498128230821734 0.0989812252461832 1.0 0.7537420302496853 4 Q9H6K4 1 +Anarthria 0.6985427844089449 1.648276301070104 0.0992959855913317 1.0 0.7548807956186272 6 Q99720 1 +Large hands 0.5915169720035519 1.647064162372098 0.0995448583492475 1.0 0.7555157106274285 11 Q9Y2B2,O43175,Q99643,P51812 4 +Brushfield spots 0.697704279768085 1.6443671541302447 0.1001003855256437 1.0 0.7566636600058708 6 P56589,Q9Y5Y5,O75381 3 +Dysostosis multiplex 0.6970598600529412 1.6413619860112745 0.100722295956604 1.0 0.7566636600058708 6 P54802,P10619 2 +Bone pain 0.5021668797584791 1.6393762660864324 0.1011349214146324 1.0 0.7566636600058708 21 P51798,P07602,Q14108,P04062,P10644 5 +Abnormal bleeding 0.3697249256495881 1.6360037043233444 0.10183881212443 1.0 0.7573069973347109 95 P51798,Q9NWM8,Q99643,Q14108,P38435,O75844,P23786,Q8NCH0,P04062,Q13126,P10644,P11117,Q9NZ08,Q14739,O76024,Q9UHX1,Q9Y487 17 +Young adult onset 0.589338194682572 1.634413343235579 0.1021720883773114 1.0 0.7573069973347109 11 P07602,P38435,O15118 3 +Gingival fibromatosis 0.7899584830870344 1.6339606745703878 0.1022671081977493 1.0 0.7573069973347109 4 Q15392 1 +Calcific stippling 0.7860070663777059 1.6176836285063971 0.105730795971223 1.0 0.7760964643241159 4 Q15125,O15228 2 +Posterior pituitary dysgenesis 0.7856146977095284 1.61606643256279 0.1060799507864793 1.0 0.7760964643241159 4 Q9UHX1 1 +Abnormal circulating acetylcarnitine concentration 0.6698357956510792 1.6147699528257502 0.1063605223349857 1.0 0.7760964643241159 7 P23786,Q9P0S2 2 +Meningitis 0.7222925029620685 1.6144672509443183 0.1064261147766134 1.0 0.7760964643241159 5 Q9NZ08 1 +Decreased activity of mitochondrial complex i 0.4956231101181598 1.6102553502846753 0.1073421223530404 1.0 0.7807524880480243 38 O75306,O43676,P03886,Q9UBX3,Q70HW3,Q86Y39,Q9Y584,Q9NPL8,Q96CU9 9 +Decreased absent ankle reflexes 0.5502386572791051 1.6096066140350618 0.1074837634016649 1.0 0.7807524880480243 15 Q7LG56,Q9H6K4,P12235,P07196 4 +Rhinitis 0.6892224826894682 1.604754827287168 0.1085477707575606 1.0 0.7822630356329565 6 P51798 1 +Abnormality of the larynx 0.4856233826864446 1.6019066318442663 0.1091762577671227 1.0 0.7855532625795019 45 P21964,P07602,P35637,Q9NZJ7,Q92804,Q9UBM7,O00192,Q15165,Q14739,Q13510,P16435,Q9UHX1 12 +Abnormal endocrine physiology 0.7806984668242658 1.595789892983503 0.1105357105850757 1.0 0.7915950809768197 4 Q13423 1 +Abnormal elasticity of skin 0.4528936425336594 1.5917946820596294 0.1114308454532047 1.0 0.7963089527339341 59 Q9Y4P3,Q9NWM8,P21281,P38435,O75844,Q9H4L7,Q8NCH0,P04062,Q13126,P51812,Q15555,O43175,P10644,Q9BV10,Q9NX14,Q9UHX1,Q9Y487 17 +Abnormal aortic valve physiology 0.4968446181851664 1.5912980727653288 0.1115425103413696 1.0 0.7963089527339341 33 O75844,Q15125,P04062,Q9UHX1 4 +Abnormality of the posterior pituitary 0.66464529472735 1.5894399131969386 0.1119611095409751 1.0 0.796999761122212 7 Q9ULK5,Q9UHX1 2 +Hydrocephalus 0.4111816833376104 1.589320079697096 0.1119881476560429 1.0 0.796999761122212 71 Q15125,P04062,P53701,Q8TAA9,Q15392,Q13509,P51798,P23786,Q96J42,Q10713,P10644,Q9UBM7,P16435,P21964,O96028,O00192,O43505,Q9ULK5,Q9H490 19 +Erythroderma 0.6217708381728526 1.581783966075568 0.1136988965693919 1.0 0.8079164205685095 9 Q15125,P48449 2 +Skin dimple 0.4964537674080099 1.5793251509016046 0.1142614958092169 1.0 0.8106533763234662 28 Q9Y4P3,O95202,P49366,Q15125,Q03164,O96028,P61978,O43909,Q9NX14,Q969X5,P53701,Q9ULK5,Q8TAA9 13 +Wormian bones 0.5256941034725071 1.5782689743265303 0.1145038303801349 1.0 0.8111131798555602 17 O75844,Q9Y487,O95831 3 +Vascular skin abnormality 0.3825794507935425 1.5768692981453525 0.1148256022348741 1.0 0.8120133665449916 117 Q15125,P98194,P03886,P04062,P10619,P53701,P00846,P06280,P51798,O75306,O75844,Q8NCH0,P04066,Q13126,P51648,Q8IZA0,Q14739,Q99643,Q9Y487,Q9Y2B2,Q9NWM8,P51812,P10644,Q9UBM7,P21964,Q14108,P38435 27 +Abnormality of fontanelles 0.4770549744606671 1.5725053416587356 0.1158334013312767 1.0 0.8167327325348818 48 P56589,Q9Y5Y5,Q15125,Q9Y487,O75844,O75718,Q8NCH0,O15228,Q9Y619,O75419,P51812,Q6NUK1,P16435,O75381,Q16134,P98175,Q9BT22 17 +Retinal pigment epithelial mottling 0.7738132147888724 1.567351027293474 0.1170326642351211 1.0 0.8216019714511161 4 P00846,Q9UG56 2 +Thoracic scoliosis 0.5614703715271858 1.5668205782315383 0.11715663597585 1.0 0.8216019714511161 13 O75844,Q9UHX1 2 +Elevated serum acid phosphatase 0.7718364034432221 1.5591774365333697 0.1189543896859874 1.0 0.8285690335442212 4 P51798,P07602 2 +Oculomotor apraxia 0.493559311741258 1.5570849890385463 0.1194503084740949 1.0 0.8285690335442212 28 Q9Y2B2,P05067,Q10713,P04062,O96008,P33897,O14773,O43292,O43924,Q13509 10 +Progressive pes cavus 0.7088423782821234 1.5545507215989158 0.1200531077851569 1.0 0.8285690335442212 5 O00400 1 +Leg muscle stiffness 0.7081981695028783 1.5516747292688882 0.1207400722852212 1.0 0.8285690335442212 5 P00846,P33897 2 +Retinal telangiectasia 0.6776361136619934 1.550445048069876 0.1210347332942873 1.0 0.8285690335442212 6 P00846,P03886 2 +Myoclonic seizure 0.4480078093273296 1.5433936840544458 0.1227352851954515 1.0 0.8285690335442212 59 Q96N66,P07602,P03886,P04062,Q9Y619,O43292,O75503,O43175,Q5XKP0,P00846,Q13510 11 +Ectopic anus 0.5302949017511865 1.542534662291002 0.1229437215472359 1.0 0.8285690335442212 16 Q9Y2B2,P53701,Q6DKJ4,Q6NUK1,P49748,P48651,Q9NX14,O60826,P16435 9 +Abnormal intraocular pressure 0.7678053361490369 1.5424986601279451 0.1229524632836467 1.0 0.8285690335442212 4 Q8NCH0,Q12797 2 +Bilateral tonic clonic seizure 0.3561803069685638 1.5388423708470451 0.1238427830162098 1.0 0.8317819059321806 87 Q86SQ9,P21281,P03886,P04062,P27544,Q9HC21,Q01105,P00846,O60566,P49748,Q99757,Q14739,Q13510,Q9NQZ5,Q9Y2B2,P07602,O15047,P51812,O43292,Q9NZJ7,P11166,O43175 22 +Aplastic clavicle 0.7667910447761161 1.5382996196109902 0.1239753727160899 1.0 0.8317819059321806 4 Q9Y2B2,Q9Y619,O75419 3 +Headache 0.4282165517618299 1.532424267434697 0.1254177728041585 1.0 0.8377687192137433 65 Q9NQZ5,Q7LG56,P03886,P23786,Q9BW27,P04062,P12235,Q8NFH4,P10644,Q9NZ08,P00846,Q8TAA9,Q99643 13 +Abnormality of chorioretinal pigmentation 0.702465950857368 1.5260600392903505 0.1269949128095597 1.0 0.8410585094411145 5 Q5XKP0 1 +Congenital sensorineural hearing impairment 0.6298372446015855 1.5236284742439157 0.1276015460254056 1.0 0.8410585094411145 8 Q9P0S2,Q16740 2 +Episodic tachypnea 0.6511266852901835 1.5232301519921878 0.1277011350113346 1.0 0.8410585094411145 7 Q10713,O43924,P22695 3 +Neck muscle weakness 0.5174959531237033 1.522803178180425 0.1278079546141768 1.0 0.8410585094411145 17 Q99720,P07602,P35637,Q9NZJ7 4 +Molar tooth sign on mri 0.7626087969899641 1.5209759614524527 0.1282658698413559 1.0 0.8410585094411145 4 Q10713 1 +Widely patent fontanelles and sutures 0.7625481697130366 1.5207247195419529 0.1283289327030481 1.0 0.8410585094411145 4 O75844 1 +Intestinal pseudo obstruction 0.6100849127494099 1.5193617696740929 0.1286714594220483 1.0 0.8410585094411145 9 P03886 1 +Bruising susceptibility 0.4883199187259279 1.5175517513082604 0.1291274379086655 1.0 0.8427153334448156 27 P51798,Q9NWM8,Q14108,P38435,Q8NCH0,P04062,Q13126 7 +Generalized hyperpigmentation 0.5687341747897645 1.5140769692532718 0.130006319122611 1.0 0.8427153334448156 11 Q13423,P51648 2 +Hepatic failure 0.4551158793109233 1.5094870592622618 0.1311743598586199 1.0 0.8427153334448156 55 Q10713,O15118,P03886,P23786,P04062,Q9Y619,Q9P0S2,P00846,Q13510 9 +Cogwheel rigidity 0.6481147162896463 1.508433588303501 0.1314435919345498 1.0 0.8427153334448156 7 P00846,P12235 2 +Postaxial polydactyly 0.4835144483390128 1.5071657967112957 0.1317681649559661 1.0 0.8427153334448156 20 Q15125,Q10713,Q96J42,O43924,O75845,Q14739,P98175 7 +Basal ganglia cysts 0.6476438448894066 1.506118964836649 0.1320366369741983 1.0 0.8427153334448156 7 P00846 1 +Agnosia 0.6261473210837263 1.5046791439657188 0.1324065876136602 1.0 0.8427153334448156 8 P05067,P33897,O96008 3 +Abnormal pleura morphology 0.4830635479899168 1.5038282621377823 0.1326255921273846 1.0 0.8427153334448156 20 Q14739,Q8NCH0 2 +Paresthesia 0.485085217532336 1.503580558749526 0.13268940003898 1.0 0.8427153334448156 23 Q7LG56,P07196,Q9H6K4,P54802,Q9NR77,Q9NZ08,P06280 7 +Head titubation 0.6465638659137161 1.5008087608437457 0.1334050320643047 1.0 0.8427153334448156 7 Q99720 1 +Positive romberg sign 0.6065201309301003 1.5002582076170012 0.1335475306299489 1.0 0.8427153334448156 9 Q9H6K4,Q8IV08 2 +Ventricular hypertrophy 0.4777459448133754 1.4978562251514265 0.1341706090469552 1.0 0.8427153334448156 42 O75208,P03886,P23786,O75844,P10253,P12235,Q6NUK1,Q9P0S2,O43772,O75431,Q9BV10,Q7LG56,P21912,P06280 14 +Breast aplasia 0.8891917488113311 1.4946799871441947 0.134997979716307 1.0 0.8427153334448156 3 Q9Y619 1 +Abnormality of the amniotic fluid 0.3546090696189052 1.494183017588265 0.1351277900834173 1.0 0.8427153334448156 89 Q15125,P21281,Q70HW3,P04062,Q9NVI7,Q9BUB7,Q9BT22,P51798,O75844,P23786,Q7LGA3,Q96J42,Q9BV10,Q14739,Q9Y2B2,O15047,P16435,Q9UBM7,P21964,Q9UHX1,O43175,Q9ULK5,Q9NSD9 23 +Cerebral dysmyelination 0.6239547172794488 1.4934064270376826 0.1353308316240249 1.0 0.8427153334448156 8 P07602,O43175 2 +Increased connective tissue 0.6239225618449646 1.493241038162872 0.1353741033863329 1.0 0.8427153334448156 8 P07196,P31751,O95831 3 +Personality changes 0.5320168389207616 1.4925853865130534 0.1355457509568089 1.0 0.8427153334448156 15 P03886 1 +Patellar aplasia 0.7554383050221756 1.491239843510494 0.1358985363936018 1.0 0.8436418651934332 4 Q9Y619 1 +Abnormality of the gastric mucosa 0.5314026549853075 1.4886215913492873 0.1365870427046644 1.0 0.8454836400236176 15 Q14739,P04062,O76024 3 +Abnormal visual electrophysiology 0.4654007134195191 1.4848413600988144 0.1375858527259676 1.0 0.8454836400236176 49 P51798,Q86SQ9,P07602,Q15067,P12235,O75503,O14773,P00846,O43924,P50897 10 +Tinnitus 0.5560372635189019 1.4842528396762242 0.1377418565075272 1.0 0.8454836400236176 12 Q9NR77,Q99643,O95831 3 +Rigidity 0.4420249482104232 1.483875753250382 0.1378418854575083 1.0 0.8454836400236176 59 Q9Y287,Q86SQ9,P07602,Q9NZJ7,Q9H6K4,Q9H2C2,P04062,P12235,Q7LG56,P00846,Q96CU9,Q15392 12 +Abnormal labia minora morphology 0.6430853527686302 1.4836916055696563 0.137890754283785 1.0 0.8454836400236176 7 Q9Y619,O75419 2 +Metaphyseal cupping 0.8862433940223395 1.483628989033366 0.1379073744054513 1.0 0.8454836400236176 3 O95831 1 +Infantile axial hypotonia 0.5634954549411753 1.483287007588562 0.1379981727739583 1.0 0.8454836400236176 11 Q13509,P07602,P17900,Q9NZJ7 4 +Loss of voice 0.8857171117908427 1.481656089238534 0.1384318265107851 1.0 0.8454836400236176 3 Q13510 1 +Hypoplastic labia minora 0.6923018953594741 1.480540534692232 0.1387290515368966 1.0 0.8454836400236176 5 Q9Y619 1 +Clitoral hypoplasia 0.6923018953594741 1.480540534692232 0.1387290515368966 1.0 0.8454836400236176 5 Q9Y619 1 +Progressive peripheral neuropathy 0.8853869485089993 1.480418346366409 0.1387616368761151 1.0 0.8454836400236176 3 P07602 1 +Ethylmalonic aciduria 0.6919130149917169 1.4787965010461512 0.1391947112944631 1.0 0.8468450544665808 5 Q9P0S2 1 +Ankylosis 0.6915008436643166 1.4769478236814475 0.1396896240404075 1.0 0.8478455709409861 5 O75844 1 +Hip pain 0.6903459050945422 1.471766643490278 0.1410839041066902 1.0 0.8495780416773779 5 O75844 1 +Constriction of peripheral visual field 0.4792699899905837 1.4697632078649023 0.1416258970095805 1.0 0.8495780416773779 21 P56589,Q9Y5Y5,Q9H061,O75381,Q15555,P00846 6 +Abnormal thoracic spine morphology 0.4821955379816795 1.4690025351630789 0.141832101601278 1.0 0.8495780416773779 29 O75844,P04062,O95831,Q9UHX1,Q13509 5 +Elevated circulating long chain fatty acid concentration 0.7498792656918636 1.4681584037282631 0.1420612002279528 1.0 0.8495780416773779 4 P23786,P33897 2 +Redundant skin 0.4815112552665428 1.4670581217148326 0.1423602450596475 1.0 0.85025354206213 26 Q9Y4P3,P38435,Q8NCH0,P51812,Q9BV10,Q9NX14,Q9Y487 7 +Abnormality of the spleen 0.3736285000749612 1.4643081065500534 0.1431097832110766 1.0 0.853614359649359 116 P21281,O15118,P04062,Q96A33,P10619,Q9NZ08,Q15392,Q9BT22,P51798,P00813,P04066,Q96J42,Q14739,Q5HYI8,Q13510,P07602,Q10713,P28070,O75845,P21964,O96028,Q14108,Q9NZJ7,P10253,P54802,O00192,P11166 27 +Short femur 0.6591020716155863 1.463128568188947 0.1434322020523251 1.0 0.8543152637634652 6 Q9UHX1 1 +Abnormality of the tongue 0.3521703490373339 1.46015215043262 0.1442482626042953 1.0 0.8565272645450048 89 P56589,Q9NWS8,Q9NQT5,P21281,P61978,P04350,P50542,Q96A33,Q9Y4P3,Q6DKJ4,O75844,Q7LGA3,P04066,Q96J42,O75431,O95831,P07196,Q13510,P98175,Q16637,Q99643,Q10713,Q9BQT8,P42356,Q9UBM7,Q9Y5Y5,P16278,O75381,P10253,Q6NUK1,P48651,P21912,O43924 33 +Congenital hypothyroidism 0.8797015853279446 1.4590996525101902 0.1445376818763235 1.0 0.8565272645450048 3 Q13423,P10644 2 +Abnormal ldl cholesterol concentration 0.543634367689281 1.4573180609534544 0.1450286035731676 1.0 0.8565272645450048 13 P50402,Q8N511,Q9Y6B6,P38571,Q15800,Q9UJS0 6 +Postaxial hand polydactyly 0.5515411879868373 1.457182366654985 0.1450660467352607 1.0 0.8565272645450048 12 Q10713,Q96J42,O75845,Q14739,O43924 5 +Skin nodule 0.4763341704538037 1.453915365923781 0.1459697721135548 1.0 0.8583473472160004 20 P35637,Q9NZ08,Q13510,Q99643,P06280 5 +Abnormality of prothrombin 0.5342272667351899 1.4505486545944866 0.1469055816279394 1.0 0.8627398489178089 14 Q5XKP0,Q9BV10 2 +Retinal arterial tortuosity 0.8765338149555664 1.4472176544763595 0.147835973468613 1.0 0.863829622945608 3 P03886 1 +Mild short stature 0.7446328828532394 1.4463545005422815 0.1480777966370985 1.0 0.863829622945608 4 Q14739 1 +Joint contracture of the hand 0.4645084781615886 1.4453744108915736 0.1483527470395405 1.0 0.863829622945608 47 Q9Y2B2,P42892,O75844,Q9Y619,O75419,Q9NR77,O43175,Q8IZA0,Q9BUB7,P07196,P16435,Q15392,Q13509 13 +Deep plantar creases 0.743729798176278 1.4425993928443672 0.1491333545208866 1.0 0.863829622945608 4 P21281,Q9Y487 2 +Lipoma 0.6346701400342973 1.4421995911986685 0.1492460758936027 1.0 0.863829622945608 7 Q9ULK5,Q8TAA9 2 +Loss of subcutaneous adipose tissue in limbs 0.742719499141272 1.438397844065718 0.1503212040065444 1.0 0.863829622945608 4 O75844 1 +Abnormality of the upper respiratory tract 0.3514046617004066 1.438089753162586 0.1504085896423341 1.0 0.863829622945608 90 P35637,Q03518,P00813,Q92804,P04066,Q9BV10,Q15165,Q14739,Q13510,P07602,Q7RTS9,P28070,P10644,Q9UBM7,P16435,P21964,Q9UHX1,Q9NZJ7,P54802,O00192 20 +Ecchymosis 0.5557521281572568 1.437641875931427 0.1505356927671297 1.0 0.863829622945608 11 Q8NCH0,P04062,P38435 3 +Abnormal larynx physiology 0.5308427519866585 1.4291536386074313 0.1529600795249108 1.0 0.8670900785971685 14 Q92804,Q13510,P35637 3 +Frontotemporal dementia 0.5738608034405333 1.427034942940608 0.1535698228663715 1.0 0.8673183197483951 10 P22626,P05067,P35637,O96008 4 +Flattened epiphysis 0.7379981682399834 1.4187546422898227 0.1559705605475922 1.0 0.8706257777249483 4 Q9NUQ7,O95831 2 +Premature loss of teeth 0.544995431267409 1.4176730159260391 0.1562862517549472 1.0 0.8706257777249483 12 O75844 1 +Aplasia hypoplasia of the patella 0.6781626406882264 1.4170232191538537 0.1564761390054827 1.0 0.8706257777249483 5 Q9Y619 1 +Inappropriate crying 0.629366962266164 1.4159949001021466 0.1567769976374373 1.0 0.8706257777249483 7 P07602,O43175 2 +Positional foot deformity 0.3562076793318422 1.4156174237296084 0.1568875471045194 1.0 0.8706257777249483 98 Q15125,Q9Y619,Q96A33,Q9NVI7,Q15907,Q8TAA9,Q15392,Q8NCH0,Q96J42,Q9BV10,P07196,P98175,Q9Y487,Q9NWM8,Q7RTS9,O75845,P16435,Q9UBM7,P21964,Q9UHX1,Q8NI60,O96028,O00192,Q9NR77 24 +Aortic regurgitation 0.4711115827402166 1.4150504053891884 0.1570537177533904 1.0 0.8706257777249483 20 O75844,Q9UHX1 2 +Arthritis 0.4701367670676044 1.414816815796286 0.1571222124134894 1.0 0.8706257777249483 40 P51798,Q14108,O75844,P28070,P04062,O00192,Q96HY6,Q9NZ08,Q14739,Q13510,P21964,P06280 12 +Neoplasm of fatty tissue 0.5715036450063168 1.4137403612031394 0.157438150058607 1.0 0.8706257777249483 10 Q9ULK5,Q8TAA9 2 +Specific learning disability 0.4233377525212757 1.4125913548407534 0.1577759124439171 1.0 0.8706257777249483 63 P22626,Q10713,P35637,Q96EK5,P03886,Q9NSD9,Q9H6K4,Q9Y619,O75419,O00192,O43505,P10644,O75845,P53701,P21964,Q13509 16 +Abnormal vascular physiology 0.465057842745499 1.410886925266876 0.158277957987948 1.0 0.8711032358475297 44 Q9NWM8,Q14108,P03886,O75844,P04062,Q9NZ08,Q14739 7 +Abnormality of the extraocular muscles 0.7353855721392997 1.4078791737034184 0.159166850943925 1.0 0.8711032358475297 4 Q7LG56,Q13509,Q9BVA1 3 +Respiratory arrest 0.6277211767719296 1.4078540436880005 0.1591742935972764 1.0 0.8711032358475297 7 P23786,P49748,O43772,P13473 4 +Incoordination 0.4026979785238088 1.4059533572580567 0.1597379755407402 1.0 0.8711032358475297 69 P07602,Q10713,O00165,Q9NZJ7,Q7RTS9,Q6DKK2,Q15067,P04062,Q9Y619,P12235,O75503,Q9NR77,Q01105,O14773,Q7LG56,P00846,Q13510 17 +Osteopetrosis 0.8650667745445302 1.4041896511950736 0.1602623826975178 1.0 0.8711032358475297 3 Q15392 1 +Short lingual frenulum 0.8650373014654524 1.4040790344382803 0.1602953159745719 1.0 0.8711032358475297 3 O75844 1 +Overtubulated long bones 0.8650373014654524 1.4040790344382803 0.1602953159745719 1.0 0.8711032358475297 3 O75844 1 +Perisylvian polymicrogyria 0.6751618556269509 1.4035166538047108 0.1604628293784369 1.0 0.8711032358475297 5 Q9BVA1,P34897,P42356 3 +Bilateral sensorineural hearing impairment 0.4717876070463113 1.4032858712026492 0.1605316096703042 1.0 0.8711032358475297 23 P07602,P35637,P03886,Q15067,Q13509 5 +Peripheral axonal degeneration 0.3618291475090516 1.4019688375477295 0.160924552537534 1.0 0.8721150157809706 79 P22626,P07602,P03886,Q9NZJ7,Q6DKK2,Q15067,Q9BQT8,P12235,O15269,Q99757,Q9NVI7,O95831,Q7LG56,P00846,O76024,Q8IV08,Q13509 17 +Eeg with polyspike wave complexes 0.6058619885360312 1.400044671655841 0.1614999417382137 1.0 0.8721150157809706 8 Q9Y2B2,P11166,Q14108 3 +Tongue fasciculations 0.5420131484280865 1.3996352460134982 0.1616225737386114 1.0 0.8721150157809706 12 Q13510,O95831 2 +Increased muscle lipid content 0.5490913489023743 1.3982556124502687 0.162036322020965 1.0 0.8721150157809706 11 P23786 1 +Hyperlipidemia 0.4731283699925878 1.3981960524579151 0.1620542018818218 1.0 0.8721150157809706 29 P50402,P23786,O75844,P28070,P50416,P31751,O95470,O75431,Q9UJS0,P38571,P22830,P06280 12 +Gastric ulcer 0.8625078758289568 1.3945854271330806 0.163140892113168 1.0 0.8738808071995288 3 P04062 1 +Meningocele 0.5484287201342384 1.3943314382935348 0.1632175415161858 1.0 0.8738808071995288 11 Q10713,O75845,Q9ULK5,Q8TAA9,P21964 5 +Bile duct proliferation 0.86237486545509 1.3940861888793017 0.1632915792775513 1.0 0.8738808071995288 3 Q5XKP0 1 +Generalized osteosclerosis 0.8623333514699495 1.393930370917617 0.1633386319431817 1.0 0.8738808071995288 3 Q15392 1 +Hypoketotic hypoglycemia 0.6045169454370534 1.3930810461534036 0.1635952839824126 1.0 0.8742302368604015 8 P23786,P49748,O43772,P31751 4 +Prenatal maternal abnormality 0.5249817903115312 1.3920265735561763 0.1639143511531746 1.0 0.874911998152868 14 O43772,P50416,Q14739,Q9ULK5,P16435,Q8TAA9 6 +Abnormal sacrum morphology 0.4721505940845597 1.3904101598087817 0.1644043630722318 1.0 0.8758717028015279 30 Q03164,Q15125,O96028,P04066,P53701,Q14739,Q9ULK5,Q8TAA9 8 +Abnormality of femur morphology 0.4116592330926911 1.3901690515655238 0.1644775489174241 1.0 0.8758717028015279 66 P51798,P07602,Q9Y487,O75844,Q7RTS9,P04062,Q7LGA3,Q9Y619,Q96A33,P04066,Q9BV10,O95831,Q14739,P16435,Q9UHX1,P06280 16 +Abnormal arterial physiology 0.4711528918823355 1.3875176796509767 0.1652839638872816 1.0 0.8772816851693249 26 Q9NWM8,O75844,Q9NZ08,Q14739,P06280 5 +Gastrointestinal obstruction 0.5240476055312971 1.386100066589325 0.1657163500538776 1.0 0.8772816851693249 14 P42892,Q01844,P33897,Q5HYI8,Q99643 5 +Nasogastric tube feeding in infancy 0.6028636999464874 1.384517715518146 0.1661999874387791 1.0 0.8772816851693249 8 P07602,Q9UHX1 2 +Abnormal corpus striatum morphology 0.4972097797060207 1.3845144800457534 0.1662009774303776 1.0 0.8772816851693249 17 P00846,O95831 2 +Zonular cataract 0.5394691058295737 1.3842303785467354 0.1662879242535748 1.0 0.8772816851693249 12 Q99797,Q9H6K4,O76024,P08670 4 +Intestinal malrotation 0.4708334410063473 1.3811296255839989 0.1672391080123414 1.0 0.8772816851693249 28 O96028,Q8NCH0,Q9BV10,Q14739,Q9UBM7,Q15392,P21964,Q9NSD9 8 +Hypolipoproteinemia 0.6020373963888632 1.3802360469943769 0.1675139786059105 1.0 0.8772816851693249 8 P38571,Q15800,Q9Y6B6 3 +Adenoma sebaceum 0.6697591603924552 1.3791782574436642 0.1678398000314298 1.0 0.8772816851693249 5 Q99643 1 +Angiofibromas 0.6697591603924552 1.3791782574436642 0.1678398000314298 1.0 0.8772816851693249 5 Q99643 1 +Leber optic atrophy 0.9925419515226842 1.3784344233382726 0.1680692014157778 1.0 0.8772816851693249 2 P03886 1 +Multiple glomerular cysts 0.9925419515226842 1.3784344233382726 0.1680692014157778 1.0 0.8772816851693249 2 P03886 1 +Low plasma citrulline 0.9925419515226842 1.3784344233382726 0.1680692014157778 1.0 0.8772816851693249 2 P03886 1 +Abnormal large intestine physiology 0.4677575935524394 1.3778677683990497 0.1682441179623652 1.0 0.8772816851693249 22 P07602,O75298,Q9NZJ7,Q8TAA9,P21964,P06280 6 +Limb muscle weakness 0.3429710893577544 1.3769252071874185 0.1685353729126777 1.0 0.8772816851693249 85 O75298,P07196,Q7RTS9,O00400,Q15067,Q9BQT8,P05023,P12235,Q13126,O15269,Q9NR77,Q7LG56,P00846,Q13510,Q99720,Q14739 16 +Fractures of the long bones 0.8553724170958713 1.3678021373116642 0.1713740185297299 1.0 0.8829270008494825 3 Q13126 1 +Progressive external ophthalmoplegia 0.5367223296870498 1.3675800808284002 0.1714435549705049 1.0 0.8829270008494825 12 P03886,O60313,Q13472,P12235,Q5ST30,Q7LG56 6 +Abnormality of visual evoked potentials 0.4660781660721884 1.3651926304736677 0.1721925140100171 1.0 0.8829270008494825 22 P51798,O75503,Q15067,P07602 4 +Abnormality of the tarsal bones 0.4688567075981714 1.364718455326042 0.1723415568232189 1.0 0.8829270008494825 29 Q15125,O75844,Q7RTS9,O43175,Q14739,P16435,Q9UHX1 7 +Migraine 0.4658396195402711 1.3633914002886265 0.1727591899232736 1.0 0.8829270008494825 22 Q9NQZ5,Q7LG56,P03886,P12235,Q9NZ08 5 +Overlapping toe 0.4743646749052269 1.3619053405330537 0.1732277605646521 1.0 0.8841017752795922 19 Q9UHX1,Q15907,Q15125,Q96A33 4 +Gait ataxia 0.4056233801130647 1.360624529655298 0.1736323756661257 1.0 0.8841017752795922 67 P07602,Q10713,Q14108,O15118,P03886,Q9NZJ7,P12235,Q9NR77,Q9NVI7,O14773,Q7LG56,P00846,Q15907,O43292,Q8IV08 15 +Cerebral inclusion bodies 0.5200039466706468 1.3604200513107143 0.1736970367977186 1.0 0.8841017752795922 14 Q9Y287,P22626,O15118,P04062,O96008,Q6Y7W6 6 +Retinal coloboma 0.5805351122676591 1.3602113429920428 0.1737630541039776 1.0 0.8841017752795922 9 Q10713,Q9UHX1 2 +Athetosis 0.5026220790508619 1.3587987745178074 0.1742103617726575 1.0 0.88493569759103 16 O43175,O14949 2 +Motor neuron atrophy 0.4651272441868059 1.3580111140221132 0.174460157583346 1.0 0.88493569759103 22 P22626,P35637,Q92804,Q13510,Q99720 5 +Cutaneous syndactyly 0.5799801025706883 1.3572061463467826 0.1747157183448524 1.0 0.88493569759103 9 P98175,P21281,Q9Y619 3 +Xerostomia 0.5110336115825339 1.3565068926171795 0.1749379438206186 1.0 0.88493569759103 15 Q92804,Q14739,P35637 3 +Abnormality of tibia morphology 0.5271409310935329 1.3552519901258406 0.1753372854741475 1.0 0.88493569759103 13 Q7RTS9,Q9BV10,O95831 3 +Abnormal systemic blood pressure 0.342087787070216 1.3529408112911403 0.1760745400785672 1.0 0.88493569759103 86 P42892,P03886,P04062,P35610,Q9BUB7,Q8TAA9,P06280,Q9Y4P3,Q13423,O75844,Q99643,P07602,Q10713,O43772,P10644,P16435,P21964,Q9NZJ7,Q9NSD9 19 +Oligomenorrhea 0.6351408641795018 1.34955244814442 0.1771595859592873 1.0 0.88493569759103 6 Q9UNE7,P31751,O15120 3 +Deep palmar crease 0.5601487297843958 1.3495331240282913 0.1771657883178798 1.0 0.88493569759103 10 P21281,Q6NUK1,O75431,P98175,Q9Y487 5 +Generalized myoclonic seizure 0.4561238154666295 1.3445548900503668 0.1787690192332065 1.0 0.88493569759103 45 Q96N66,Q86SQ9,Q8NHS3,P07602,P16278,P03886,Q9NZJ7,Q6PJG6,P04062,Q9Y619,P11166,P21912,Q01105,O43175,P51649,P00846,Q13510,O60566 18 +Hyperconvex nail 0.594335322260614 1.3402750636978915 0.18015593541936 1.0 0.8883656038388706 8 O95202,P42892,O96028,Q9Y619,P51812 5 +Short ribs 0.5581469358625917 1.3381870781872336 0.1808354603145643 1.0 0.8883656038388706 10 Q14739,Q9Y619 2 +Abnormality of lipoprotein cholesterol concentration 0.5164011968845492 1.337504460103249 0.1810580273948503 1.0 0.8883656038388706 14 Q8N511 1 +Osteopenia 0.4097862987637844 1.3347028730421655 0.1819736128875224 1.0 0.8897356535002262 65 Q9NWM8,P07602,Q14108,Q9NSD9,O75844,Q9NZJ7,P04062,Q13126,O43175,P10644,O43292,Q9H490,Q9Y487 13 +Keratoconjunctivitis 0.5931272282799314 1.3339990331609688 0.1822041733917578 1.0 0.8897356535002262 8 Q14739 1 +Photophobia 0.4641940327576254 1.3329241839320505 0.1825566853101192 1.0 0.8897356535002262 34 Q9Y287,Q86SQ9,P48449,P07602,P51648,Q9NZ08 6 +Chorea 0.3421299192295904 1.3305746040981137 0.1833290234028781 1.0 0.8897356535002262 88 Q96N66,O75306,Q9BWD1,P07602,P35637,P03886,Q9NZJ7,Q9H6K4,Q9NZ01,Q5XKP0,P00846,Q99720 12 +Retinal arteriolar tortuosity 0.537653682889148 1.3303778748284945 0.1833938006005975 1.0 0.8897356535002262 11 Q9Y4P3,P00846,P21964 3 +Telecanthus 0.460902604257025 1.3296468536835335 0.1836346530746864 1.0 0.8897356535002262 39 Q03164,Q15125,Q86XL3,P21281,Q96EK5,O75844,Q8NCH0,P51812,Q16134,Q9H490,P21964 11 +Cardiac conduction abnormality 0.4643087846576591 1.3287153546752015 0.1839418971903594 1.0 0.8897356535002262 31 O75306,P03886,P23786,P49748,O43772,Q7LG56,P00846,Q9H490,P06280 9 +Abnormal gastrointestinal motility 0.4635188867549963 1.328623391386332 0.1839722508459971 1.0 0.8897356535002262 26 P35637,P03886,Q99757,Q7LG56,Q5HYI8,Q9UBM7,O76024,P06280 8 +Abnormality of primary teeth 0.5147614694604151 1.3270641101092124 0.1844874762516319 1.0 0.8910394069700914 14 O75844 1 +Upper limb spasticity 0.573902254194403 1.324262660268981 0.1854158269339583 1.0 0.8930255465152704 9 P35637,Q99720 2 +Papule 0.4970770394406542 1.3216993775043997 0.1862682760423677 1.0 0.8930255465152704 16 O75844,Q9NZ08,Q99643,P38435 4 +Desquamation of skin soon after birth 0.8420982065885679 1.317980804538992 0.1875100737887587 1.0 0.8939892541466669 3 P04062 1 +Opisthotonus 0.4615751657795783 1.31699445467577 0.1878404833476892 1.0 0.8940033004329083 25 P07602,P35637,P04062,O43175,P11117,Q99720 6 +Hypoglycemic coma 0.5721266267903915 1.3146270049978774 0.1886352896572769 1.0 0.8968518610240357 9 Q13423,Q16134 2 +Lactic acidosis 0.3447854515938275 1.311253685498285 0.1897720700953018 1.0 0.8979333097752454 93 Q8NI60,O43676,O75306,Q10713,Q99797,O75208,P03886,Q70HW3,Q86Y39,Q9NP80,P12235,Q9P0S2,Q9NPL8,Q5XKP0,Q7LG56,Q9Y6M9,Q96CU9 17 +Decreased light and dark adapted electroretinogram amplitude 0.8400745092690101 1.3103872465672264 0.1900648658115535 1.0 0.8979333097752454 3 P50897 1 +Infantile spasms 0.4615145255017336 1.3088433580615912 0.1905874165650232 1.0 0.8979333097752454 33 P00846,Q13510,P03886 3 +Hypertrophic cardiomyopathy 0.3546363469428296 1.306298359307398 0.1914511148521727 1.0 0.8979333097752454 106 O43676,Q99797,P03886,Q9H061,Q9NVI7,Q9BUB7,P53701,P00846,Q96CU9,P06280,O75306,Q13423,Q9Y4P3,Q86Y39,Q9NPL8,Q7KZN9,Q9Y6M9,P10253,P12235,P54802,Q5XKP0 21 +Cytochrome c oxidase negative muscle fibers 0.5701246973605664 1.3037574484366314 0.19231629506851 1.0 0.8979333097752454 9 Q9Y2R0,P12235 2 +Prominent superficial blood vessels 0.5109150142994205 1.3025479262293655 0.1927291457234479 1.0 0.8979333097752454 14 O75844,Q9Y487,Q6NUK1 3 +Telangiectasia 0.4594604253729302 1.3012553279353771 0.1931710725976612 1.0 0.8979333097752454 36 O75306,P03886,P10619,Q8IZA0,P00846,Q14739,Q99643,P06280 8 +Adducted thumb 0.4605024604335457 1.300432363209328 0.1934528238650426 1.0 0.8979333097752454 28 P42892,Q8NCH0,O43175 3 +Depression 0.3492639250787225 1.2963314230226028 0.1948613271196035 1.0 0.8979333097752454 100 P35637,P03886,P04062,P06280,Q9Y4P3,P50897,Q92804,Q6DKK2,Q9NZ01,Q15165,O76024,Q96N66,P07602,P51812,P10644,P21964,Q9NZJ7,P12235,O00192,Q7LG56 20 +Abnormality of the nasolabial region 0.6233858259721012 1.2936048734449193 0.1958019382496914 1.0 0.8979333097752454 6 Q8NCH0 1 +Prominent nasolabial fold 0.6233858259721012 1.2936048734449193 0.1958019382496914 1.0 0.8979333097752454 6 Q8NCH0 1 +Hemiparesis 0.4926821827825756 1.2922369988352995 0.1962750822868824 1.0 0.8979333097752454 16 Q9NZ08,P03886 2 +Macular purpura 0.5163710928182419 1.2882400189573209 0.1976624253191552 1.0 0.8979333097752454 13 P51798,Q8NCH0,P04062,P38435 4 +Somatic sensory dysfunction 0.3540236164310657 1.2869435974471632 0.1981139479180398 1.0 0.8979333097752454 107 Q9BRK0,Q9H6K4,Q9Y619,Q9NZ08,P00846,P06280,O00400,Q8NCH0,O15269,O95831,P07196,P07602,O00165,O14773,Q9NZJ7,P54802,Q9NR77,Q7LG56,Q8IV08 19 +Ichthyosis 0.4561352319446954 1.2834660411110104 0.1993288495435907 1.0 0.8979333097752454 38 Q9Y2B2,Q9Y5Y5,Q15125,P48449,P50402,P04062,P51648,O95470,O43175,O75381,Q15800 11 +Talipes equinovarus 0.3570374723208908 1.2819597871219583 0.1998567530657942 1.0 0.8979333097752454 78 Q15125,Q9Y619,Q96A33,Q15907,Q8TAA9,Q15392,Q8NCH0,Q9BV10,P98175,Q9Y487,Q9NWM8,Q7RTS9,O75845,P16435,P21964,Q8NI60,O96028,O00192,Q9NR77 19 +Aplasia hypoplasia of the clavicles 0.5153408004556821 1.2818158800125974 0.1999072422155325 1.0 0.8979333097752454 13 Q9Y2B2,O75844,Q9Y619,O75419 4 +Nemaline bodies 0.7050303216575704 1.2813059676616765 0.2000862176043183 1.0 0.8979333097752454 4 O43676 1 +Aplasia hypoplasia of the phalanges of the toes 0.8322481035882687 1.2810285547452334 0.2001836365731097 1.0 0.8979333097752454 3 P21281 1 +Hyperintensity of cerebral white matter on mri 0.4553071753794409 1.2780348139967794 0.2012371512772051 1.0 0.8979333097752454 23 P07602,Q9NZJ7,P10253,O75503,P17900,P21912,Q9C0D9 7 +Recurrent paroxysmal headache 0.5474380942727073 1.277366757406479 0.2014727952076045 1.0 0.8979333097752454 10 Q99643,P03886 2 +Slurred speech 0.5652094105940317 1.277044598196906 0.201586502477888 1.0 0.8979333097752454 9 Q9NW15,P33897,P16278,Q9Y487 4 +Fetal distress 0.4563312319833651 1.276610842023328 0.201739672215568 1.0 0.8979333097752454 25 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q9Y6M9,Q96CU9 7 +Orthostatic hypotension due to autonomic dysfunction 0.5818213137589643 1.2751693096393009 0.202249321566089 1.0 0.8979333097752454 8 P07602,P04062,Q9NZJ7 3 +Increased csf lactate 0.4329070859793993 1.275105556516856 0.2022718829343173 1.0 0.8979333097752454 54 O75306,O43676,Q8NI60,P03886,Q86Y39,Q7KZN9,Q9NPL8,P13073,O95831,P00846,Q96CU9 11 +Retinal dysplasia 0.5646109797969734 1.2737900040550243 0.202737848668433 1.0 0.8979333097752454 9 Q10713,O43505,O43924 3 +Sensory axonal neuropathy 0.5063752194297941 1.273569038587356 0.2028161907831152 1.0 0.8979333097752454 14 Q15067,Q8IV08,O95831 3 +Leukodystrophy 0.4208629374859642 1.2713113921153816 0.2036178911202566 1.0 0.8979942827157285 59 O75306,O43676,Q53FT3,P07602,Q9Y5Y5,P03886,Q15067,Q86Y39,Q7KZN9,Q9NPL8,Q9Y6M9,Q96CU9 12 +Sporadic 0.4531979122138182 1.2676520404283769 0.2049222388236136 1.0 0.8979942827157285 22 O95202,Q9BWD1,O96028,P04062,P51812,P48651,P21912,Q99643 8 +Spastic diplegia 0.4550962071083191 1.2670867554037628 0.2051242708300042 1.0 0.8979942827157285 25 Q13509,P07602,P35637,P51648,Q99720 5 +Myelomeningocele 0.6448719340397384 1.2667849676558331 0.205232188579679 1.0 0.8979942827157285 5 Q9ULK5,Q8TAA9 2 +Abnormality of the peripheral nervous system 0.348638128680481 1.2655877379626317 0.2056607183971182 1.0 0.8979942827157285 102 P42892,Q15125,Q96EK5,P04062,Q9Y619,Q13509,P06280,O15269,Q99757,O95831,P07196,O76024,Q99720,Q9NQZ5,Q9Y2B2,P07602,Q10713,Q15067,Q9UBM7,P21964,Q9NZJ7,Q9NR77,Q7LG56 23 +Abnormality of the tonsils 0.598840475421225 1.2644301650499743 0.2060756715514147 1.0 0.8979942827157285 7 O00192,P00813,P31751,P21964 4 +Wide anterior fontanel 0.4546689224356781 1.2637905618628884 0.2063052096714164 1.0 0.8979942827157285 25 P56589,Q9Y5Y5,Q15125,O75718,O75419,Q6NUK1,O75381,Q16134,P16435,Q9Y487 10 +Tetraplegia 0.5047910789037879 1.2634464544658446 0.2064287782868783 1.0 0.8979942827157285 14 O95831 1 +Abnormally lax or hyperextensible skin 0.4500982036101609 1.260902537133624 0.2073439639974825 1.0 0.8979942827157285 42 Q9Y4P3,Q9NWM8,Q15904,P38435,Q8NCH0,P04062,P51812,Q6NUK1,Q15555,O75787,Q9BV10,Q9NX14,Q9UHX1,Q9Y487 14 +Poor eye contact 0.4514550683091213 1.2566978934925288 0.208863051200739 1.0 0.8979942827157285 40 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q5XKP0,Q9Y6M9,Q96CU9,Q9UHX1 9 +Abnormal pupillary function 0.6153734434251643 1.2554046078568786 0.2093319174659922 1.0 0.8979942827157285 6 P07602,Q9NR77 2 +Leukoencephalopathy 0.3447625134405419 1.2550618174652228 0.2094563200060306 1.0 0.8979942827157285 98 O43676,P03886,Q01105,Q9BUB7,Q96CU9,O75306,Q86Y39,Q9NPL8,O95831,Q9H9P8,Q9C0D9,P07602,O75503,Q9Y6M9,Q9UHX1,Q53FT3,O96028,Q9NZJ7,Q7LG56 19 +Metatarsus adductus 0.5181805616003462 1.2547423610457582 0.2095723025718561 1.0 0.8979942827157285 12 O96028,P50542,Q9UBM7,Q15392,Q13509 5 +Venous insufficiency 0.6400687308982342 1.2450548060088826 0.2131116051193768 1.0 0.8979942827157285 5 P04062,P21964 2 +Varicose veins 0.6400687308982342 1.2450548060088826 0.2131116051193768 1.0 0.8979942827157285 5 P04062,P21964 2 +Subcutaneous nodule 0.4767876046001861 1.244002775887858 0.2134985412885761 1.0 0.8979942827157285 17 Q9NZ08,Q13510,P35637,P06280 4 +Narrow vertebral interpedicular distance 0.8218523484326656 1.242061239319047 0.2142139681913564 1.0 0.8979942827157285 3 P10644 1 +Vertebral arch anomaly 0.8218523484326656 1.242061239319047 0.2142139681913564 1.0 0.8979942827157285 3 P10644 1 +Chronic pulmonary obstruction 0.612153794323279 1.2400422585168156 0.2149597642082961 1.0 0.8984203825239865 6 O00192,P21964,P06280 3 +Sensory neuropathy 0.4527238390293001 1.2396158671218838 0.2151175089694115 1.0 0.8984203825239865 34 P22626,P03886,Q15067,O15269,O95831,P00846,Q8IV08 7 +Torsion dystonia 0.6948561416745082 1.2388393319596285 0.2154050047154252 1.0 0.8987995128262812 4 P11166,P04350 2 +Furrowed tongue 0.6109040353656966 1.2340774862255348 0.2171740319325019 1.0 0.9022669477290736 6 P61978,P21912,Q96J42,Q99643 4 +Microcornea 0.4519420588027363 1.2332806961165117 0.2174710574058536 1.0 0.9022669477290736 28 Q9NWM8,Q15125,Q8NCH0,Q96J42,O43505,O75845 6 +Gastrointestinal hemorrhage 0.4519689023322548 1.2316986324461696 0.2180616808768534 1.0 0.9022669477290736 29 P21964,O00192,P21912,Q9UHX1,Q9NZ08,Q14739,O76024,Q99643 8 +Wide cranial sutures 0.5920893084721116 1.230778072398897 0.2184058788369323 1.0 0.9022669477290736 7 O75844,P98175 2 +Aplasia hypoplasia of the cerebral white matter 0.5732305756557103 1.2303659340009 0.2185601040773352 1.0 0.9022669477290736 8 P11166,P03886 2 +Gingival bleeding 0.5390154864590456 1.2294001694797223 0.2189218067558926 1.0 0.9022669477290736 10 P04062,Q14108 2 +Insulin resistant diabetes mellitus 0.538848035364712 1.2284455037843154 0.2192797749787758 1.0 0.9022669477290736 10 O75844,P31751 2 +Retinopathy 0.4512875357729985 1.2281368014552616 0.219395618062377 1.0 0.9022669477290736 28 O75306,Q8NHS3,Q5JRA6,O96028,Q15555,Q99757,P51648,Q9Y6B6,Q9NZ08,P00846 10 +Intellectual disability progressive 0.5133635258421212 1.2253165734905251 0.2204559662700973 1.0 0.9044074096709616 12 Q9H9P8,P53701,O95831 3 +Abnormal heart sound 0.6914290736563469 1.224535767058094 0.2207501821761299 1.0 0.9044074096709616 4 P10644 1 +Abdominal distention 0.4475230105050199 1.224509746702262 0.2207599917595184 1.0 0.9044074096709616 22 P07602,Q9NZJ7,Q7RTS9,P04062,Q96HY6,Q9UGP8,Q9Y6B6,Q7LG56,Q01844 9 +Saccadic oscillation 0.9505904288377875 1.2225054351326363 0.2215165497919373 1.0 0.9044074096709616 2 P04062 1 +Opsoclonus 0.9505904288377875 1.2225054351326363 0.2215165497919373 1.0 0.9044074096709616 2 P04062 1 +Megaloblastic anemia 0.5551205211064452 1.2221142526925672 0.2216644240083125 1.0 0.9044074096709616 9 O43175,O76024,P00374 3 +Soft skin 0.5708437498633211 1.2179046502910973 0.2232602088498971 1.0 0.909158551011747 8 Q9NWM8,Q13126 2 +Decreased circulating cortisol level 0.5706719422966405 1.2170074662614518 0.2236013751489394 1.0 0.9095128532525796 8 Q13423,P16435,P33897 3 +Abnormal caudate nucleus morphology 0.5185842810127932 1.216614019009706 0.2237511063163215 1.0 0.9095128532525796 11 P00846 1 +Nausea and vomiting 0.3716784971274884 1.216106383369128 0.2239443991921978 1.0 0.9095128532525796 138 O43676,P42892,P35637,P03886,Q9Y619,P35610,P11117,Q9NZ08,P00846,Q96CU9,P06280,O75306,Q13423,Q9Y4P3,P23786,Q92804,Q86Y39,Q9NP80,Q9Y584,P49748,Q9NPL8,Q8IZA0,Q15165,Q5HYI8,Q99643,Q96EY8,P07602,P51571,Q9Y6M9,Q9NZJ7,O43175,P22695,Q7LG56,Q16134,Q9NSD9 35 +Short nail 0.6332614859585811 1.2142462326320445 0.2246537106992447 1.0 0.9098544855847852 5 O75844 1 +Absent hypoplastic paranasal sinuses 0.8143042117430034 1.2137974945743066 0.2248250633016464 1.0 0.9098544855847852 3 P04066 1 +Abnormal electroretinogram 0.4495655158371312 1.2109769770855716 0.2259042284949355 1.0 0.910034010359904 31 Q86SQ9,P12235,O14773,P00846,O43924,P50897 6 +Severe short stature 0.4486514534503676 1.2100397141173682 0.2262636541406983 1.0 0.910034010359904 27 P16278,Q7RTS9,Q9NX14,Q9Y619,O75419,Q96HY6,P10619,P53701,Q15392 9 +Memory impairment 0.4485913252424358 1.2082940221752003 0.2269341870163197 1.0 0.9111268018256282 35 P07602,Q7LG56,Q9NZJ7,P03886,Q9BRK0,Q9NZ08 6 +Steroid resistant nephrotic syndrome 0.6315045948221959 1.2062932538573807 0.2277044379149564 1.0 0.9111631267732292 5 Q9BW27,Q8N1F7 2 +Symptomatic seizures 0.5680490676674329 1.2033075659489632 0.2288573223155632 1.0 0.9116382786920736 8 Q13423,P31751 2 +Abnormality of blood circulation 0.4005901990971999 1.2027675686503072 0.2290662781885586 1.0 0.911675805787042 64 P38435,O75844,P23786,P04062,P10644,Q9UHX1,Q9NZ08,Q14739,O76024,Q99643,Q9Y487 11 +Angiokeratoma 0.8097606465651079 1.1967994271970102 0.2313847415991556 1.0 0.9134902357647158 3 P04066,P06280 2 +Prominent sternum 0.8097606465650975 1.1967994271969709 0.231384741599171 1.0 0.9134902357647158 3 Q7RTS9,O95831 2 +Poor wound healing 0.6029425671672184 1.1960616233343584 0.2316725122111842 1.0 0.9134902357647158 6 P04062 1 +Decreased calvarial ossification 0.684287655980963 1.1947359747129631 0.2321902022480027 1.0 0.9134902357647158 4 O75844 1 +Abnormal renal tubule morphology 0.445732281004429 1.190632212442917 0.2337980001018498 1.0 0.9134902357647158 26 O75306,P03886,P23786,P00846,P06280 5 +Abnormality of corneal size 0.4450598952300078 1.190584246754881 0.2338168389398864 1.0 0.9134902357647158 38 Q9Y4P3,Q9NWM8,Q15125,O96028,Q96EK5,Q8NCH0,Q96J42,O43505 8 +Eeg with irregular generalized spike and wave complexes 0.8079960205112656 1.1902012158114896 0.2339673154511425 1.0 0.9134902357647158 3 Q9NQZ5 1 +Purpura 0.4599599584746701 1.1891221327286028 0.2343916101168219 1.0 0.9134902357647158 18 P51798,P38435,Q8NCH0,P04062,P10644 5 +Coronal craniosynostosis 0.6276624760181472 1.1888997826645324 0.2344791056834134 1.0 0.9134902357647158 5 P16435,Q9NX62 2 +Low frustration tolerance 0.5652917555581403 1.1888994287293655 0.234479244976641 1.0 0.9134902357647158 8 P04062,Q9UHX1 2 +Skin rash 0.4599282633609965 1.1888965300853265 0.2344803857569384 1.0 0.9134902357647158 18 Q06136,P28070,Q13546,P40763,Q9H4L7,P21912,Q99643,Q14739 8 +Respiratory failure 0.3931588058233931 1.1872552913569705 0.2351269373939131 1.0 0.915072382412938 66 O75306,P07602,P35637,Q9NZJ7,Q92804,P23786,Q9NSD9,Q70HW3,P10253,Q9Y619,O75419,Q5XKP0,Q15165,Q9BUB7,P53701,Q13510,Q9BT22 17 +Hypoglycemic seizures 0.5831177977550492 1.1860084643766835 0.2356189568468942 1.0 0.9162068202837956 7 Q13423,P31751 2 +Abnormal circulating free fatty acid concentration 0.681017480582711 1.1810945869362313 0.2375651500802356 1.0 0.9205989407058426 4 P49748,O75431 2 +Small basal ganglia 0.5468236322840421 1.1768556327336304 0.2392531331612348 1.0 0.9205989407058426 9 P00846 1 +Decreased muscle mass 0.4489489002425246 1.1764572952776418 0.2394121878278248 1.0 0.9205989407058426 19 O96028,Q8NCH0,P04066,Q8TAA9,Q9Y487 5 +Abnormality of endocrine pancreas physiology 0.6791003826242817 1.173099219039221 0.2407560196623119 1.0 0.9205989407058426 4 Q14739 1 +Generalized lipodystrophy 0.6788565634613469 1.1720824583323142 0.2411639519101012 1.0 0.9205989407058426 4 O75844 1 +Toxemia of pregnancy 0.5978078773354509 1.171531097246488 0.2413853656356148 1.0 0.9205989407058426 6 O43772,Q14739 2 +Occipital meningocele 0.6237448439859417 1.1711638602432586 0.2415329188101971 1.0 0.9205989407058426 5 Q10713,P21964 2 +Abnormal circulating fatty acid anion concentration 0.4903328793795375 1.1708381158571983 0.241663853673645 1.0 0.9205989407058426 14 P23786,Q9P0S2,P49748 3 +Follicular thyroid carcinoma 0.8021399225136687 1.1683198258169762 0.242677781145453 1.0 0.9205989407058426 3 Q99643 1 +Keratitis 0.5448284336633725 1.1659627026854893 0.2436295255424467 1.0 0.9205989407058426 9 Q14739 1 +Abnormal diaphysis morphology 0.3997291637168542 1.1629782053429856 0.2448383452056206 1.0 0.9205989407058426 63 O75718,Q9Y619,Q9NX62,Q13509,Q9Y4P3,P51798,Q7LGA3,Q13126,O75419,Q96J42,O75431,Q14739,Q9Y487,Q9HC07,Q7RTS9,P51812,P16435,P16278,Q96HY6,Q9NR77 20 +Impaired visuospatial constructive cognition 0.5599828303085623 1.1611428075503023 0.2455838286331597 1.0 0.9205989407058426 8 P11166,Q10713,P03886 3 +Abnormality of the knee 0.3277582181538166 1.1610444391927432 0.2456238278001719 1.0 0.9205989407058426 85 Q15125,Q86XL3,Q9Y619,Q9NX62,O75340,P51798,Q13509,Q9Y4P3,P23786,Q7LGA3,O75419,O75431,O95831,Q13510,Q7RTS9,P21964,P16278,O00192,Q96HY6,Q9NR77,Q969X5,P21912,Q15041,Q9NUQ7 24 +Increased total bilirubin 0.6759567563348204 1.1599917664397286 0.2460521583532853 1.0 0.9205989407058426 4 P23786 1 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9334990677439348 1.159425367176897 0.2462828416852824 1.0 0.9205989407058426 2 O75503 1 +Generalized onset seizure 0.3441316670009441 1.158566491608506 0.2466329340191944 1.0 0.9205989407058426 106 Q86SQ9,P03886,P04062,Q9Y619,O14653,Q01105,Q9NVI7,P00846,O60566,Q8NHS3,O43909,Q9NW15,P05023,Q9Y320,Q9NZ01,Q13510,P00374,Q96N66,P07602,P51812,O75503,O43292,Q14108,P16278,Q9NZJ7,Q6PJG6,P11166,O43175,P21912,Q9NUQ7 30 +Glucose intolerance 0.3448359213764989 1.15771641589207 0.246979782582555 1.0 0.9205989407058426 107 O75306,O43676,Q86SQ9,P03886,O75844,Q5HYI8,Q9Y6M9,Q86Y39,P12235,P31751,Q9NPL8,P10644,Q7LG56,P00846,Q9ULK5,Q96CU9,O76024,Q8TAA9 18 +Neurofibromas 0.6751757227975579 1.156735907661875 0.2473802744681705 1.0 0.9205989407058426 4 Q99643 1 +Hypokinesia 0.4880479176999222 1.1561708429786368 0.2476112834646127 1.0 0.9205989407058426 14 P04062,P12235,O95831 3 +Hyperthyroidism 0.5259893393549634 1.1550347198060935 0.2480762087848975 1.0 0.9205989407058426 10 Q7LG56,P21964,P12235 3 +Macrovesicular hepatic steatosis 0.5587202672178148 1.154539198426224 0.2482791776698518 1.0 0.9205989407058426 8 P23786,Q7LG56,Q5XKP0 3 +Abnormal csf metabolite level 0.4068530244423883 1.1542387475920275 0.248402300912363 1.0 0.9205989407058426 60 O75306,O43676,Q8NI60,P03886,Q86Y39,Q7KZN9,Q9NPL8,P13073,O95831,P00846,Q96CU9 11 +Abnormality of bladder morphology 0.5253631228019001 1.15145518544226 0.2495450217812576 1.0 0.9205989407058426 10 Q9NWM8,P16435 2 +Abnormal delivery 0.4377748216235373 1.1502043005667268 0.2500597353661375 1.0 0.9205989407058426 22 O75844,O75718,Q9Y619,Q9UBM7,Q9Y487 5 +Dysmetria 0.403643087261506 1.1474707907997534 0.2511870983987223 1.0 0.9205989407058426 61 Q5JRX3,Q9Y4P3,Q9NW15,Q6DKK2,Q9NP80,Q9NPL8,Q10713,O75503,O75027,P42356,O75787,O14773,Q6P4A7,O43292,Q9Y5Y5,Q6PJG6,Q13472,P33897,Q7LG56,Q8IV08 20 +Short middle phalanx of finger 0.9300807955251652 1.1468520995244311 0.2514427524996483 1.0 0.9205989407058426 2 Q9UHX1 1 +Delayed fine motor development 0.5411191181528303 1.145703419987661 0.2519178882940371 1.0 0.9205989407058426 9 P51798,Q13509 2 +Multifocal cerebral white matter abnormalities 0.6179765964885293 1.1450517838106848 0.2521877069591882 1.0 0.9205989407058426 5 Q9Y619 1 +Abnormal rib cage morphology 0.3543794193297817 1.1424958160345189 0.253247984185156 1.0 0.9205989407058426 76 P21281,Q9Y619,Q8TAA9,P51798,P00813,O75844,P04066,O75419,Q9BV10,O95831,Q14739,Q7RTS9,Q9UBM7,P16435,Q9UHX1,Q03164,O96028,P54802,Q96HY6 19 +Abnormal pupillary light reflex 0.6171873231275495 1.141479259410879 0.2536705381763013 1.0 0.9205989407058426 5 P07602,Q9NR77 2 +Slow pupillary light response 0.6171873231275495 1.141479259410879 0.2536705381763013 1.0 0.9205989407058426 5 P07602,Q9NR77 2 +Aplasia hypoplasia of the ribs 0.4378831314953962 1.1389800396276757 0.2547114795753302 1.0 0.9205989407058426 24 Q03164,P21281,Q9Y619,Q9BV10,Q14739,Q8TAA9,Q9UHX1 7 +Myositis 0.5555415259978004 1.1379097301073544 0.255158177883297 1.0 0.9205989407058426 8 Q9NZ08,P28070 2 +Abnormal chorioretinal morphology 0.4401316824370545 1.1362636666428652 0.2558462320310122 1.0 0.9205989407058426 30 P56589,Q9Y5Y5,Q10713,Q9NX14,Q9Y619,Q96J42,O43505,Q5XKP0,P53701,O75381 10 +Abnormal choroid morphology 0.4401316824370545 1.1362636666428652 0.2558462320310122 1.0 0.9205989407058426 30 P56589,Q9Y5Y5,Q10713,Q9NX14,Q9Y619,Q96J42,O43505,Q5XKP0,P53701,O75381 10 +Dysesthesia 0.5731481092185812 1.1362122177967784 0.2558677583936002 1.0 0.9205989407058426 7 Q8NCH0 1 +Agenesis of cerebellar vermis 0.7934032567139292 1.1357253607646738 0.256071523240263 1.0 0.9205989407058426 3 Q10713 1 +Inability to walk 0.3315841340274782 1.1354867647332587 0.256171424266665 1.0 0.9205989407058426 92 P35637,O14949,Q9NVI7,P00846,Q96CU9,Q13509,O15269,P07196,Q13510,Q9C0D9,Q99720,Q96N66,Q7RTS9,O75503,O43292,P12235,P11166,Q9NR77,Q7LG56 19 +Clonus 0.4377592423587931 1.1341086831909049 0.2567489617561906 1.0 0.9205989407058426 39 Q53FT3,P07602,P35637,Q9NZJ7,O00400,Q9BQT8,Q9Y619,O75027,Q9C0D9,Q99720 10 +Exaggerated startle response 0.5387914331044549 1.1329855612639923 0.2572203168122355 1.0 0.9205989407058426 9 P17900,P06865 2 +Male pseudohermaphroditism 0.6693695750707672 1.1325420355949702 0.257406622240895 1.0 0.9205989407058426 4 P53701,Q96J42 2 +Insidious onset 0.6151591888445185 1.132299886272006 0.257508377916694 1.0 0.9205989407058426 5 P04062 1 +Mixed demyelinating and axonal polyneuropathy 0.7924779700818598 1.132277264817714 0.2575178853001167 1.0 0.9205989407058426 3 P03886 1 +Aplasia hypoplasia of the sacrum 0.6690504556653061 1.1312128441097504 0.2579655171900654 1.0 0.9205989407058426 4 Q9ULK5,Q8TAA9 2 +Cyanosis 0.4421993316021816 1.1269441180309587 0.2597661086293756 1.0 0.9205989407058426 19 O75844,P04066,P51812,O43772,P98175 5 +Frontal balding 0.6672689630395408 1.1237937844758532 0.2611005189102164 1.0 0.9205989407058426 4 P11166 1 +Progressive sensorineural hearing impairment 0.5365264041481921 1.1206070951563607 0.2624551435407563 1.0 0.9205989407058426 9 P03886,O60313,P49736,P00403,O76024 5 +Sparse eyelashes 0.4666188687577464 1.1166513293919424 0.2641434355217655 1.0 0.9205989407058426 16 O75844,Q15125 2 +Focal t2 hyperintense basal ganglia lesion 0.4332230939055752 1.1154383704969149 0.2646626144763218 1.0 0.9205989407058426 22 O75306,P00846,Q96CU9,P03886 4 +Flat occiput 0.4662146252323092 1.1139190414572488 0.2653139197463119 1.0 0.9205989407058426 16 P56589,Q9Y5Y5,Q9BUB7,O75381,Q13509 5 +Abnormal size of the clitoris 0.432037775254062 1.1135638349914572 0.2654663485867707 1.0 0.9205989407058426 21 P56589,Q9Y5Y5,Q9NX14,Q9Y619,O75419,P16435,P53701,O75381,Q9UBM7 9 +Abnormal heart rate variability 0.6647237922157578 1.1131980704494682 0.2656233712072144 1.0 0.9205989407058426 4 P07602 1 +Red eye 0.4660421581985138 1.1127532753329874 0.2658144077988307 1.0 0.9205989407058426 16 Q9NZ08,Q14739 2 +Sclerocornea 0.5348185080857543 1.1112717227563265 0.2664514071424599 1.0 0.9205989407058426 9 P53701,O96028,Q6NUK1,Q96J42,Q9NX14,Q9UBM7 6 +Overlapping fingers 0.5504013742135985 1.11101044618773 0.2665638528931562 1.0 0.9205989407058426 8 Q15125 1 +Biparietal narrowing 0.5178427733955486 1.1084436791387773 0.2676702498861194 1.0 0.9205989407058426 10 Q10713,O43924,O75845 3 +Aplasia hypoplasia of the sternum 0.663344985777576 1.107459949633747 0.2680951189391916 1.0 0.9205989407058426 4 P98175,Q9Y619 2 +Titubation 0.5176311835732801 1.1072329673665178 0.2681932174763539 1.0 0.9205989407058426 10 Q99720 1 +Axial dystonia 0.919204474829078 1.1069557241110488 0.2683130715562871 1.0 0.9205989407058426 2 Q99720 1 +Vacuolated lymphocytes 0.7851900947046775 1.1051483517301708 0.269095312236717 1.0 0.9205989407058426 3 P04066 1 +Disproportionate short trunk short stature 0.6086998763444518 1.1030735832705465 0.2699952116671205 1.0 0.9205989407058426 5 Q7RTS9,Q9UHX1 2 +Abnormal response to endocrine stimulation test 0.7839823030913806 1.100657743259809 0.271045643959678 1.0 0.9205989407058426 3 Q13423 1 +Lissencephaly 0.4145222081764801 1.0978644836590172 0.2722636686580535 1.0 0.9210224165148414 54 Q86XL3,Q96EK5,P23786,O43175,O43505,Q9BV10,Q16134,Q15392,Q13509 9 +Arm dystonia 0.7821333225566087 1.0937863180018053 0.2740487061617283 1.0 0.9238701647272524 3 Q99720 1 +Sea blue histiocytosis 0.7820863453550688 1.0936117856032832 0.2741252780663399 1.0 0.9238701647272524 3 O15118 1 +Death in infancy 0.3958808618156199 1.0934673646848496 0.2741886503327104 1.0 0.9238701647272524 62 P56589,Q9NWS8,O75718,P04062,P50542,Q9HC21,Q9P0S2,Q9BUB7,Q9BT22,Q6DKJ4,P49748,P20674,O43464,P07602,Q15904,Q13057,Q15067,O14656,Q9Y5Y5,P16278,Q9NZJ7,Q6PJG6,Q6NUK1,O75381,P38571 25 +Chronic rhinitis 0.7815918711347383 1.0917748404270085 0.2749320803019877 1.0 0.9240167204976364 3 P51798 1 +Abnormal atrioventricular conduction 0.4780102841631615 1.0916629551034036 0.2749812736308441 1.0 0.9240167204976364 14 P50402,P49748,O43772,Q7LG56,P06280 5 +Biliary cirrhosis 0.5641792538457168 1.0913969524831384 0.2750982528128345 1.0 0.9240167204976364 7 Q14739,Q9UJW0 2 +Abnormal blood glucose concentration 0.3284321119100136 1.0905315695301792 0.2754790547054611 1.0 0.9240167204976364 92 O43676,P03886,Q9P0S2,P35610,O95470,P31751,Q96CU9,O75306,Q13423,O75844,P23786,Q86Y39,P49748,Q9NPL8,Q9BV10,O43772,Q9Y6M9,Q5XKP0,P22695,Q16134,Q9NSD9 21 +Abnormality of the ribs 0.3900965386038766 1.0895900698809085 0.2758937592536261 1.0 0.9240167204976364 64 P51798,Q03164,P00813,O96028,P21281,O75844,Q7RTS9,Q9Y619,O75419,P54802,Q96HY6,Q9BV10,O95831,Q14739,Q9UBM7,P16435,Q8TAA9,Q9UHX1 18 +Ophthalmoparesis 0.3501987722719119 1.0892304586051658 0.2760522704047436 1.0 0.9240167204976364 76 O75306,Q86SQ9,Q10713,P03886,P04062,Q7KZN9,P12235,Q9P0S2,P00846,Q96CU9,O76024,Q13509 12 +Dysdiadochokinesis 0.4771062360721907 1.0858480729085465 0.2775462137957538 1.0 0.9264624633077294 14 O75503 1 +Back pain 0.4272820411335097 1.0853503770278754 0.2777665016280095 1.0 0.9264624633077294 20 P51798,P50402,P36551,P33897,Q9UGP8,Q5HYI8,Q8TAA9 7 +Abnormal tricuspid valve morphology 0.4901092361745642 1.0828027270524163 0.2788959948606069 1.0 0.9279506863343177 12 P53701,Q6DKJ4,Q15233,P51812,O00192,Q9NX14,P21964 7 +Maternal diabetes 0.9117464263517644 1.0797040069891517 0.2802740090044557 1.0 0.9279506863343177 2 Q9ULK5 1 +Asymmetry of spinal facet joints 0.9117464263517644 1.0797040069891517 0.2802740090044557 1.0 0.9279506863343177 2 Q9ULK5 1 +Absence of the sacrum 0.9117464263517644 1.0797040069891517 0.2802740090044557 1.0 0.9279506863343177 2 Q9ULK5 1 +Abnormal macular morphology 0.4312295388564488 1.0734195164932965 0.2830829318128049 1.0 0.9320409002413116 27 Q13510,P51648,P04062,P50897 4 +Abnormality of the biliary system 0.3441481416137146 1.0734025434966732 0.2830905438183273 1.0 0.9320409002413116 114 O15118,P04062,Q96A33,Q9Y4P3,P04066,P49748,Q14739,Q5HYI8,Q13510,Q9UJW0,P00374,P07602,Q10713,P10644,O75845,Q9UBM7,P21964,Q9Y5Y5,O96028,Q14108,Q9NZJ7,O00192,P11166,Q5XKP0,O75381,Q16134,Q9NSD9 27 +Arthrogryposis multiplex congenita 0.4315070087336549 1.069641663003073 0.284780634236891 1.0 0.9327356734476274 36 O75844,Q8NCH0,O43175,Q15392 4 +Hyporeflexia of upper limbs 0.7755672987255029 1.0694173235317286 0.2848816647297625 1.0 0.9327356734476274 3 Q15067,Q9NR77 2 +Hypopigmented skin patches 0.4301682095792712 1.0692150765887327 0.2849727667081412 1.0 0.9327356734476274 26 P21964,P07602,Q15125,Q9NZJ7,Q9NX14,O00192,Q8IZA0,P53701,Q99643 9 +Increased adipose tissue 0.6540459264278087 1.0688015454761706 0.2851591028053735 1.0 0.9327356734476274 4 P31751 1 +Distal arthrogryposis 0.6010480192307921 1.068476644687331 0.2853055600822967 1.0 0.9327356734476274 5 Q8NCH0,Q96A33 2 +Turricephaly 0.5266762777426854 1.066752875361563 0.2860834435023538 1.0 0.9327356734476274 9 O00192,P16435,P21964,Q6NUK1 4 +Babinski sign 0.3248463396956794 1.06197566788534 0.288246731505873 1.0 0.9327356734476274 90 P07602,P35637,O75298,Q9NZJ7,O00400,Q9H6K4,Q15067,Q9BRK0,Q6DKK2,P51812,O75027,Q9NR77,O95831,P07196,P00846,O14773,Q9C0D9,Q99720 18 +Moderate global developmental delay 0.5097158470779908 1.061926846624252 0.288268896280651 1.0 0.9327356734476274 10 O43175,O95831 2 +Microtia third degree 0.906152889993778 1.0593275330197691 0.2894506400006555 1.0 0.9327356734476274 2 Q9Y619 1 +Impaired social interactions 0.4156846825562358 1.058173348095652 0.2899764195866117 1.0 0.9327356734476274 51 O75306,O43676,P03886,Q15067,Q86Y39,Q9NPL8,Q5XKP0,Q9Y6M9,Q96CU9,Q9UHX1,Q13509 11 +Generalized onset motor seizure 0.4043239881586673 1.0576649646429452 0.2902082133832697 1.0 0.9327356734476274 57 Q86SQ9,P03886,P04062,Q9Y619,Q01105,P00846,O60566,Q8NHS3,Q9Y320,P51649,Q13510,Q96N66,P07602,P16278,Q9NZJ7,Q6PJG6,P11166,O43175,P21912 19 +Vitritis 0.7721479639415565 1.0567483727548963 0.2906264419122997 1.0 0.9327356734476274 3 P53701,Q9NX14 2 +Cachexia 0.4412120542057919 1.0553866148915174 0.2912485420489747 1.0 0.9327356734476274 18 P07602,P35637,Q9NZJ7,P04062,Q99720 5 +Pulmonary hypoplasia 0.4292515249096497 1.0543448308878742 0.2917250706366643 1.0 0.9327356734476274 28 O75844,O75419,O43175,Q14739,Q16134,P98175,Q8TAA9 7 +Proportionate short stature 0.4287021732761167 1.0527332874846969 0.2924632479213713 1.0 0.9327356734476274 38 P16278,Q7RTS9,Q9NX14,Q9Y619,O75419,P21912,Q96HY6,P10619,P10644,P53701,Q14739,Q15392,Q9C0D9 13 +Micromelia 0.4257639564305776 1.0515676429714411 0.2929979596603074 1.0 0.9327356734476274 23 Q96HY6,O43175,P10644,Q14739,Q9UBM7,Q15392,Q9UHX1 7 +Inflammatory abnormality of the eye 0.4296283943881147 1.0505274905519602 0.2934756585981291 1.0 0.9327356734476274 34 Q9NZ08,Q14739,P51648,Q15800 4 +Gastrointestinal stroma tumor 0.7704115989993946 1.0503209855072644 0.2935705599498588 1.0 0.9327356734476274 3 Q99643 1 +Retrognathia 0.3308694720071625 1.0450848384577278 0.2959837607400652 1.0 0.9327356734476274 80 Q15125,O75844,Q8NCH0,P04062,Q7LGA3,Q9Y619,O43175,P53701,Q15392,Q9UHX1 10 +Peptic ulcer 0.4899897425443259 1.045080632396992 0.2959857045233152 1.0 0.9327356734476274 11 P04062,O76024 2 +Scarring 0.4281838848580411 1.042982919193673 0.2969562037142934 1.0 0.9327356734476274 29 Q9NWM8,Q8NCH0,Q15125 3 +Echolalia 0.5373907231752646 1.042904581698485 0.2969924874347427 1.0 0.9327356734476274 8 Q9NX14,P53701,O75787,Q9UHX1 4 +Flat face 0.4266416145181345 1.0416481953118788 0.297574815252775 1.0 0.9327356734476274 26 P56589,Q9Y5Y5,Q03164,Q15125,Q9BUB7,O75381,Q9NX62,Q9Y487 8 +Sparse or absent eyelashes 0.4244316313395425 1.04131808142312 0.2977279476358843 1.0 0.9327356734476274 23 O75844,Q15125,O43175 3 +Hypointensity of cerebral white matter on mri 0.5705357374369592 1.0412388613077852 0.2977647038928224 1.0 0.9327356734476274 6 P07602 1 +Spondyloepimetaphyseal dysplasia 0.5540222135518483 1.0406546773269827 0.2980358450414964 1.0 0.9327356734476274 7 Q7RTS9,O95831 2 +Enlarged thorax 0.4473184007855074 1.0396786467040495 0.298489224426786 1.0 0.9327356734476274 17 O75844,Q14739,P04066 3 +Abnormal tongue physiology 0.4301773523197314 1.0385868270045888 0.2989969348546719 1.0 0.9327356734476274 19 Q9NWS8,Q9NQT5,Q9BQT8,P10253,O95831,Q13510,Q16637 7 +Partial agenesis of the corpus callosum 0.4825153562267272 1.03616035744478 0.3001273376508468 1.0 0.9327356734476274 12 Q15392 1 +Weakness due to upper motor neuron dysfunction 0.3614694106337849 1.0349593806933186 0.3006878812326614 1.0 0.9327356734476274 142 P56589,P35637,P03886,Q9BRK0,Q9H6K4,P04062,Q9Y619,Q9NZ08,P00846,Q96CU9,O75306,Q13423,O00400,Q6DKK2,Q9NP80,O95831,Q9H9P8,Q13510,Q9C0D9,Q96B26,P07602,O75298,Q7RTS9,Q7KZN9,Q9Y5Y5,Q9UBX3,Q9NZJ7,P11166,Q5XKP0,Q7LG56,Q15041 31 +Brain imaging abnormality 0.4267386529764995 1.032655162384332 0.3017653035183376 1.0 0.9327356734476274 37 O75306,P07602,P03886,Q9NZJ7,P35610,Q9P0S2,P11166,P33897,Q9BV10,Q969X5,Q9BT22 11 +Tracheal stenosis 0.5685774081998922 1.031892855209403 0.3021223133872772 1.0 0.9327356734476274 6 Q96HY6,Q15125,Q9UBM7 3 +Abnormality of the glenoid fossa 0.8983840894965738 1.031123051334312 0.3024831192707631 1.0 0.9327356734476274 2 Q9Y619 1 +Atlantoaxial instability 0.8983840894965704 1.0311230513342995 0.3024831192707689 1.0 0.9327356734476274 2 Q9NWM8 1 +Pleural effusion 0.4875803235129696 1.0306012500877533 0.3027278496282664 1.0 0.9327356734476274 11 Q14739 1 +Generalized edema 0.5926510678746184 1.0305574819714614 0.3027483833263655 1.0 0.9327356734476274 5 O43175 1 +Generalized clonic seizure 0.566539315420305 1.02216901497276 0.3067009131325879 1.0 0.9360831476972574 6 P07602 1 +Cold induced muscle cramps 0.7616357700325065 1.0179026571284695 0.308724218761875 1.0 0.939747472033982 3 P23786 1 +Bacterial endocarditis 0.8943443132380273 1.01650393496903 0.3093894746314831 1.0 0.9405193011252472 2 P04062 1 +Apnea 0.3159844085504876 1.015340077289046 0.3099437464650194 1.0 0.9415777776586928 83 P03886,P04062,Q96A33,P00846,Q96CU9,O60566,P51798,O75306,P23786,Q86Y39,O76024,P98175,P07602,Q10713,Q7KZN9,P51812,O43772,P42356,O75251,Q9NZJ7,P11166,O43924 22 +Abnormality of the fetal cardiovascular system 0.5888172855361488 1.0132659708686145 0.3109331369080104 1.0 0.943492979016452 5 Q9Y2B2,P16435 2 +Hallucinations 0.4229617269151802 1.0131528028420007 0.3109871802142212 1.0 0.943492979016452 40 P07602,P35637,Q9NZJ7,Q6DKK2,P04062,O75503,Q9BQE5,O76024,P21964,P50897 10 +Hypotension 0.4204265194679132 1.0104984983189549 0.3122565185271366 1.0 0.9441368619254432 23 Q13423,P07602,Q9NZJ7,P04062,P35610 5 +Quadriceps muscle weakness 0.5880984777469082 1.0100256462402806 0.312483003031621 1.0 0.9441368619254432 5 P12235 1 +Abnormality of bone mineral density 0.3520035430584947 1.0098504116607463 0.3125669635582253 1.0 0.9441368619254432 131 Q15125,P04062,Q15392,P06280,P51798,O75844,Q13126,O95831,Q14739,Q13510,Q9Y487,Q9NWM8,P07602,Q9HC07,P10644,O43292,O96028,Q14108,Q9NZJ7,P12235,P54802,O43175,Q7LG56,Q9H490 24 +Dicarboxylic aciduria 0.4210630525308755 1.008988902788084 0.3129799562844444 1.0 0.9441368619254432 24 Q96EY8,P23786,Q9P0S2,P49748,O43772,Q9H9P8,Q16134 7 +Abnormal pelvis bone morphology 0.8921690490988191 1.00864619099422 0.3131443463527148 1.0 0.9441368619254432 2 Q7RTS9 1 +Motor seizure 0.3380001494587596 1.007519917746721 0.3136849910850714 1.0 0.9441368619254432 112 Q86SQ9,P03886,P04062,Q9Y619,O14653,Q01105,P00846,O60566,O75340,Q8NHS3,O43909,Q8N442,Q9Y320,Q9NZ01,P51649,Q13510,Q96N66,P07602,O75503,P42356,O75787,P13073,O43292,P16278,Q9UBX3,Q9NZJ7,Q6PJG6,P11166,O43175,Q5XKP0,P21912,Q9NUQ7 32 +Sensory ataxia 0.5874319053993703 1.0070213062018232 0.3139245355196118 1.0 0.9441368619254432 5 P54802,Q9NR77 2 +Vertebral segmentation defect 0.4241653514759924 1.0067864028040376 0.3140374301961075 1.0 0.9441368619254432 31 Q15125,O96028,P21281,Q9Y619,P16435,Q8TAA9,Q9UHX1 7 +Social and occupational deterioration 0.8915475450590302 1.0064029780146566 0.3142217616832465 1.0 0.9441368619254432 2 Q9BQE5 1 +Negativism 0.8915475450590302 1.0064029780146566 0.3142217616832465 1.0 0.9441368619254432 2 Q9BQE5 1 +Shuffling gait 0.499865900711371 1.0055312871576052 0.3146410918307243 1.0 0.9445434616127328 10 O75844 1 +Equinovarus deformity 0.5623059673099521 1.001982077236244 0.3163522491459669 1.0 0.9464580389557944 6 Q9NR77,P21281 2 +Aplasia hypoplasia of the breasts 0.5462049056391207 1.0016311890476457 0.3165217517015657 1.0 0.9464580389557944 7 Q9Y619 1 +Peripheral axonal neuropathy 0.3871283996774993 1.0009154310546016 0.3168676956066858 1.0 0.9464654142995644 62 P22626,P07602,P03886,Q9NZJ7,Q15067,O15269,P12235,Q9NVI7,O95831,Q7LG56,P00846,O76024,Q8IV08,Q13509 14 +Peripheral hypermyelination 0.7566453913443272 0.999521558760258 0.3175421007983079 1.0 0.9464654142995644 3 Q9NR77 1 +Abnormal sternum morphology 0.3336402339795914 0.9990626642819348 0.3177643360635735 1.0 0.9464654142995644 107 O75718,P04062,Q9Y619,Q96A33,Q9NVI7,O60566,Q9Y4P3,Q8NCH0,Q7LGA3,Q15555,O75431,O95831,Q14739,P55795,Q13510,P98175,Q99643,Q9Y487,Q9Y2B2,Q7RTS9,P51812,P42356,Q9UHX1,Q03164,P50402,O96028,P16278,Q9H490,Q9NSD9 29 +Aplasia hypoplasia of the capital femoral epiphysis 0.5456889346102125 0.9990569286870165 0.3177671143654041 1.0 0.9464654142995644 7 Q7RTS9,Q8WVQ1,O43909,Q7LGA3 4 +Abducens palsy 0.8887507768800373 0.9963189388965908 0.3190952046542223 1.0 0.9485660312720507 2 P07602 1 +Hyperesthesia 0.8887507768800373 0.9963189388965908 0.3190952046542223 1.0 0.9485660312720507 2 P07602 1 +Arrhinencephaly 0.4981576977923588 0.995752357562342 0.3193704838346889 1.0 0.9487670615349112 10 Q8TAA9,P21281,P21964 3 +Abnormality of chromosome segregation 0.6362640558940249 0.9951384836009948 0.3196689159498076 1.0 0.949036567235004 4 Q14739 1 +Protuberant abdomen 0.5840707152657105 0.9918798046179138 0.321256161769295 1.0 0.9513354451562052 5 P04062 1 +Abnormal talus morphology 0.4148456329913408 0.9910886405855868 0.3216422992542571 1.0 0.9518028920289512 20 O75844,O43175,P16435,Q9UHX1 4 +Long fingers 0.3423867180455347 0.9893555425748004 0.3224892178602976 1.0 0.9534599287687224 76 P21964,P42892,Q15125,O96028,Q03164,Q96EK5,P23786,Q8NCH0,P51812,O00192,Q9BV10,Q15907,P55795,P16435,Q9UHX1 15 +Thickened ribs 0.7538078955548577 0.989088954421246 0.3226196213343062 1.0 0.9534599287687224 3 P54802,P16278 2 +Abnormal nephron morphology 0.3833331577602841 0.9877398646522852 0.3232800654570282 1.0 0.9539830049163532 63 O75306,Q9Y4P3,Q14108,P03886,P23786,Q9BW27,Q8NFH4,O95470,Q9NZ08,P00846,Q99643,P06280 12 +Clonic seizure 0.5433615907473285 0.9874481342410094 0.3234229972894356 1.0 0.9539830049163532 7 P07602 1 +Malrotation of small bowel 0.6340816003138168 0.9861270831086476 0.3240707550267094 1.0 0.9546610443049874 4 Q8NCH0 1 +Abnormal iliac wing morphology 0.4799257063476613 0.9845996980926786 0.3248207380352643 1.0 0.9549265076497864 11 P16278,Q7RTS9,P51812,O95831,Q8TAA9 5 +Abnormality of subcutaneous fat tissue 0.4470500633338002 0.984241318750111 0.3249968744573031 1.0 0.9549265076497864 16 O75844,O43175,O75431,Q9Y487 4 +Delayed epiphyseal ossification 0.6332469200327066 0.9826826498177376 0.3257636525142078 1.0 0.955949986086972 4 Q9UG56 1 +Anotia 0.7515931665887897 0.980955977637596 0.3266144509971149 1.0 0.9564875164498357 3 Q9Y619 1 +Bladder diverticulum 0.5244660239316512 0.9752894028773038 0.3294167255489166 1.0 0.9586656172184714 8 Q9NWM8 1 +Transient ischemic attack 0.5405778384068509 0.9735691240653376 0.3302705230974063 1.0 0.9588588587633116 7 O75844 1 +Sagittal craniosynostosis 0.5800001019990788 0.973561568857103 0.3302742760056207 1.0 0.9588588587633116 5 P21281,O75419 2 +Glomerular sclerosis 0.4201389233616926 0.9730419834780818 0.3305324365402091 1.0 0.9588588587633116 32 Q14108,P03886,Q9BW27,Q8NFH4,O95470,O75431,P21912,Q8N1F7,Q99643 9 +Genu varum 0.4776375404689662 0.9708510154804332 0.3316224740317905 1.0 0.9597530203891446 11 Q7RTS9,Q96HY6,Q9NUQ7,Q9Y619 4 +Abnormal clavicle morphology 0.4127821949021065 0.9669301807074616 0.3335789379020952 1.0 0.96219833792593 21 Q9Y2B2,O75844,Q9Y619,O75419,Q14739 5 +Cortical cataract 0.7464582993344986 0.96213459388191 0.3359819988054977 1.0 0.9666653538121605 3 Q9H6K4 1 +Pain 0.3759043192903146 0.9618592170274288 0.3361203271495128 1.0 0.9666653538121605 172 P42892,P35637,Q9BRK0,Q9H6K4,Q70HW3,P04062,Q9NZ08,P00846,Q8TAA9,P06280,P51798,Q13423,Q9Y4P3,P22626,O75844,P23786,Q92804,O15269,P49748,Q15165,Q14739,Q5HYI8,Q13510,Q15800,Q99643,P07602,P28070,P10644,P21964,P50402,Q14108,Q9NZJ7,Q9BW27,P12235,O00192,Q9NR77,Q8NFH4,Q7LG56 38 +Abnormality of the anterior fontanelle 0.4187309020373718 0.9617296312674402 0.3361854338383723 1.0 0.9666653538121605 35 P56589,Q9Y5Y5,Q15125,O75718,Q9Y619,O75419,P51812,Q6NUK1,O75381,Q16134,P16435,Q9Y487 12 +Abscess 0.5210401369562396 0.9573856005400284 0.3383726636830781 1.0 0.9692944829893316 8 Q5HYI8 1 +Coxa vara 0.4568898173866317 0.9557344747501856 0.339206400442209 1.0 0.9698410232585544 14 Q8WVQ1,Q7RTS9,O75718,P50542,Q96HY6,O95831,Q9NUQ7,Q9Y487 8 +Adrenal hyperplasia 0.5753830407992739 0.9528125401329122 0.340685059432106 1.0 0.9698410232585544 5 P16435,P10644 2 +Focal dystonia 0.4119266002432925 0.95244931942628 0.3408691571071542 1.0 0.9698410232585544 22 Q9NQZ5,Q99720,Q13509 3 +Retinal detachment 0.4563540179415783 0.9522866333058332 0.3409516348908874 1.0 0.9698410232585544 14 Q8NCH0,Q9BV10 2 +Abnormality of the intrahepatic bile duct 0.6258483320219718 0.952202499231851 0.3409942937699051 1.0 0.9698410232585544 4 Q10713 1 +Persistent head lag 0.536232216456548 0.9519190354460888 0.3411380448466259 1.0 0.9698410232585544 7 Q5XKP0 1 +Nocturia 0.7433690517822855 0.9508359133000256 0.3416876785810063 1.0 0.9698410232585544 3 P12235 1 +Multiple mitochondrial dna deletions 0.7433690517822855 0.9508359133000256 0.3416876785810063 1.0 0.9698410232585544 3 P12235 1 +Delayed cranial suture closure 0.416509933366686 0.9500600539664068 0.342081738979326 1.0 0.9698410232585544 29 O75844,O75718,Q8NCH0,P51812,O75381,P16435,Q9Y487 7 +Poor motor coordination 0.462414980488527 0.9498824806011648 0.342171969685443 1.0 0.9698410232585544 13 O75503 1 +Impaired vibration sensation at ankles 0.7428340315753357 0.9488810747240612 0.3426811009813983 1.0 0.9699856545543364 3 Q9BRK0 1 +Microdontia 0.4150551407611344 0.9420209668098996 0.3461819054682424 1.0 0.9719320144149936 28 Q9Y4P3,Q9Y2B2,P21281,Q7LGA3,Q9Y619,Q96A33,Q15555,Q9Y487 8 +Adrenal insufficiency 0.4142846730159416 0.9401425299933448 0.3471444558710557 1.0 0.9719320144149936 27 P56589,Q13423,Q9Y5Y5,P50542,O95470,P33897,O75381,P16435 8 +Abnormality of metacarpal epiphyses 0.572482312857848 0.9397936942679972 0.3473233939344187 1.0 0.9719320144149936 5 O96028,P16435,P51812 3 +Temporal pattern 0.5491413634696032 0.9393260633569126 0.3475633609782611 1.0 0.9719320144149936 6 P04062 1 +Incomplete penetrance 0.4152514750524529 0.9371587616455588 0.3486768987785988 1.0 0.9719320144149936 30 P03886 1 +Juvenile onset 0.4111667811700581 0.9366376683192044 0.3489449689201156 1.0 0.9719320144149936 44 P51798,O15118,P54802,O75027,Q9NR77,O14773,Q13510 7 +Absent brainstem auditory responses 0.7393348010372494 0.9361103845648552 0.3492163568639181 1.0 0.9719320144149936 3 P07196 1 +Abnormality of the gallbladder 0.415391042475319 0.9353766180525596 0.3495942424884819 1.0 0.9719320144149936 36 Q9Y4P3,P07602,O96028,Q9NZJ7,P04062,P04066,Q96A33,O75845,Q9UBM7,P21964 10 +Diffuse cerebral atrophy 0.43974950164649 0.9348304970692768 0.3498756601333037 1.0 0.9719320144149936 16 P16278,P07602,Q10713,Q9NZJ7 4 +Abnormal pyramidal sign 0.343076645070325 0.9342477868068104 0.3501760908080171 1.0 0.9719320144149936 126 P35637,Q9BRK0,Q9H6K4,Q9Y619,P17900,Q9NZ08,P00846,O75306,O00400,Q6DKK2,P04066,P51648,O95831,Q9H9P8,Q9UHD1,P07196,Q9C0D9,Q99720,P07602,O75298,P51572,Q15067,P51812,O75027,O14773,Q8NI60,O75251,Q9NZJ7,Q6PJG6,P11166,Q9NR77,P33897,Q9UEY8,Q7LG56,P21912 35 +Agenesis of corpus callosum 0.3144166180348451 0.9318703161041426 0.3514035498495484 1.0 0.9719320144149936 82 Q10713,Q86XL3,P03886,P23786,Q7LGA3,O43175,O43505,P53701,Q9ULK5,Q15392,Q9UHX1,Q13509 12 +Cutis laxa 0.4150457003596918 0.9317231693502216 0.3514796093912604 1.0 0.9719320144149936 32 Q9Y4P3,Q15904,P38435,Q8NCH0,P51812,Q6NUK1,O75787,Q9BV10,Q9NX14,Q9Y487 10 +Limb dystonia 0.4460712873106728 0.9294693117778978 0.3526459220078619 1.0 0.9719320144149936 15 Q5BJH7,Q99720 2 +Spinal muscular atrophy 0.5014429532731602 0.928859448291615 0.3529619309660299 1.0 0.9719320144149936 9 Q13510 1 +Erythema 0.408784256731636 0.9283904133684652 0.3532050895267247 1.0 0.9719320144149936 22 Q9Y2B2,Q15125,P98194,P03886,Q9NX14,P51648,P53701 7 +Epistaxis 0.4704337070813053 0.9275854321262588 0.3536226572851553 1.0 0.9721431535113564 11 P04062,P38435 2 +Progressive spasticity 0.4454452657544112 0.9253418871741445 0.3547880968726302 1.0 0.9735896784450736 15 P51812,P07602,Q9C0D9,Q9NZJ7 4 +Abnormal cns myelination 0.3556441452059777 0.9245551417647436 0.3551973559790378 1.0 0.973870289186045 145 O43676,P35637,P03886,Q96CU9,O75306,O00400,Q86Y39,Q7LGA3,Q9Y584,P51648,Q9NPL8,Q99757,O95831,Q9H9P8,Q99720,Q9Y2B2,P07602,Q15067,Q7KZN9,Q9Y6M9,Q53FT3,Q9Y5Y5,Q9NZJ7,P10253,O43175,Q5BJH7,Q9H490 27 +Long toe 0.4851162375842663 0.9211500008460348 0.3569721182215359 1.0 0.9766510740420976 10 P23786,Q9UHX1 2 +Middle age onset 0.4999222147462145 0.9205640633863814 0.3572780716415296 1.0 0.9768209462223766 9 P07602 1 +Polydactyly 0.4083928617404119 0.9202116589016418 0.3574621628548509 1.0 0.9768209462223766 45 P21964,Q15125,Q10713,O96028,Q15067,O75419,Q96J42,O43924,O75845,Q14739,Q9UBM7,P98175,Q9UHX1 13 +Abnormal renal cortex morphology 0.3994412755292444 0.919406981142198 0.3578827391697583 1.0 0.977385675592723 52 Q14108,P03886,Q9BW27,Q8NFH4,O95470,Q9NZ08,P00846,Q16134,Q99643,P06280 10 +Shoulder girdle muscle weakness 0.4507850712904788 0.9164635266585558 0.3594238290975029 1.0 0.97876777966124 14 P07602,P12235,O14979,Q9NZJ7 4 +Agitation 0.4130493101346819 0.9145518399402416 0.3604269513762637 1.0 0.97876777966124 33 P42892,P48449,P05067,P35637,Q92804,Q6PJG6,P04062,O96008,P35610,P10644,Q15165,Q6Y7W6 12 +Abnormal anterior chamber morphology 0.5668068800732327 0.9143638312934388 0.3605257002536974 1.0 0.97876777966124 5 Q8NCH0 1 +Axonal degeneration 0.4986229735605804 0.9134791929785876 0.3609905718611708 1.0 0.978976820846577 9 Q6DKK2,Q99757,Q9BQT8,P33897 4 +Anterior rib cupping 0.6160602009627005 0.9120365049062916 0.3617495011100153 1.0 0.979166747968993 4 O95831 1 +Progressive spastic paraparesis 0.7326002760411694 0.9116072415996088 0.3619755089256051 1.0 0.9791984015873828 3 Q9C0D9 1 +Exercise intolerance 0.4119369721217121 0.908416883572271 0.3636580088577554 1.0 0.9799497962502072 37 Q8NI60,P03886,P23786,Q9Y2R0,Q9H2D1,P12235,Q7LG56 7 +Abnormal optical coherence tomography 0.7314267951507576 0.9073481846994028 0.3642227008702847 1.0 0.9799497962502072 3 Q9C0D9,P04439 2 +Abnormal peripheral nervous system physiology 0.3930900383794508 0.9070570772727556 0.3643766146698597 1.0 0.9799497962502072 55 Q9NQZ5,Q15125,P07602,Q9NZJ7,O15269,Q9Y619,Q9NR77,O95831,Q7LG56,Q99720 10 +Aganglionic megacolon 0.4354368014843329 0.9056598970785054 0.3651158949486683 1.0 0.9799497962502072 16 Q9Y2B2,P42892,Q10713,Q96EK5,Q9UBM7,P21964 6 +Tremor 0.3698412361049519 0.9035268255700628 0.3662463576306225 1.0 0.9799497962502072 169 Q9Y287,Q86SQ9,P35637,P03886,Q9BRK0,Q9H6K4,P04062,O14653,Q9BUB7,P00846,P51798,O75306,Q9Y4P3,Q6DKK2,O95831,Q13510,O76024,Q99643,Q99720,Q9NQZ5,P07602,Q10713,O75503,O75027,O14773,O43292,Q8NI60,Q14108,Q9NZJ7,Q9H2C2,P12235,Q9NR77,Q7LG56,O43924 34 +Posterior polar cataract 0.8626476072094335 0.9031137681814772 0.3664655174878888 1.0 0.9799497962502072 2 Q9Y287 1 +Tongue nodules 0.8623368551895557 0.9020151258834171 0.3670488327330421 1.0 0.9799497962502072 2 O43924 1 +Alveolar ridge overgrowth 0.8623368551895411 0.9020151258833646 0.3670488327330701 1.0 0.9799497962502072 2 Q15392 1 +Abnormal cervical spine morphology 0.5411278987178125 0.9013054971344294 0.3674259118140088 1.0 0.9799497962502072 6 Q8NCH0 1 +Telangiectasia of the skin 0.4110785122914873 0.898096111993708 0.3691343116612398 1.0 0.9799497962502072 19 Q14739,P06280 2 +Reduced brain n acetyl aspartate level by mrs 0.7282229927676502 0.8957369493329078 0.3703932713320768 1.0 0.9799497962502072 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.7282229927676502 0.8957369493329078 0.3703932713320768 1.0 0.9799497962502072 3 P07602 1 +Abnormal brain choline level by mrs 0.7282229927676502 0.8957369493329078 0.3703932713320768 1.0 0.9799497962502072 3 P07602 1 +Aplasia hypoplasia involving the skeletal musculature 0.4649290227036122 0.8945564248029836 0.3710242543667132 1.0 0.9799497962502072 11 Q9NR77,O43175,O43505 3 +Tapered finger 0.410569775298683 0.893891960456178 0.3713796996820901 1.0 0.9799497962502072 34 P42892,Q03164,Q96EK5,P23786,Q8NCH0,P51812,Q15555,Q9H4L7,Q15907 9 +Abnormal morphology of the musculature of the neck 0.4471310457048247 0.8929755938130701 0.3718702428255316 1.0 0.9799497962502072 14 Q13509,Q99720 2 +Aplasia hypoplasia involving bones of the lower limbs 0.3105903443267653 0.8913153900959349 0.3727599945206024 1.0 0.9799497962502072 87 P21281,Q9Y619,Q96A33,Q9NX62,Q13509,P00813,Q7LGA3,O75419,Q9BV10,O95831,Q13510,Q9Y2B2,Q7RTS9,P13073,P10644,Q9UBM7,Q9UHX1,Q03164,O96028,Q96HY6 20 +Oligosacchariduria 0.6106810490113294 0.8900505405109441 0.3734387487145674 1.0 0.9799497962502072 4 P04066,P10253 2 +Retrocollis 0.7261994522630181 0.8884161538178664 0.374316939225469 1.0 0.9799497962502072 3 Q99720 1 +Basal ganglia gliosis 0.4939970983276344 0.8882730054755151 0.3743939166393617 1.0 0.9799497962502072 9 P00846 1 +Slow saccadic eye movements 0.4582088952754919 0.8869200411441853 0.3751219508955159 1.0 0.9799497962502072 12 Q8IV08 1 +Extramedullary hematopoiesis 0.6096517824156626 0.8858514029283439 0.3756976063051194 1.0 0.9808927789760516 4 Q14739 1 +Limited elbow extension 0.4624489955366597 0.8796883921058919 0.3790281394011519 1.0 0.9828487905356772 11 Q7RTS9,Q9H6K4 2 +Preaxial polydactyly 0.4380152904976688 0.8763897535073052 0.3808181867552251 1.0 0.9841538774815024 15 O96028,O43924,Q9UHX1,O75419 4 +Ambiguous genitalia male 0.8542573026724485 0.8735512055714942 0.3823627088362591 1.0 0.9841538774815024 2 Q15392 1 +Ketotic hypoglycemia 0.8533250466127895 0.8702797617650787 0.3841475361250741 1.0 0.9841538774815024 2 Q13423 1 +Pancreatic islet cell hyperplasia 0.8533250466127852 0.8702797617650637 0.3841475361250823 1.0 0.9841538774815024 2 Q14739 1 +Hepatosplenomegaly 0.4070958732354046 0.8700726665457411 0.384260694004809 1.0 0.9841538774815024 38 P51798,P04062,P10619,Q14739,Q13510 5 +Coxa valga 0.4072505989311791 0.8699717966756048 0.3843158171991292 1.0 0.9841538774815024 19 P16278,O75844,P04066,Q9Y619,P51812,Q96A33 6 +Abnormal ossification involving the femoral head and neck 0.5565123456882891 0.8684016319000633 0.3851745018094921 1.0 0.9841538774815024 5 Q7RTS9,Q14739 2 +Spina bifida occulta 0.4070100999824241 0.8682056256713477 0.3852817750778825 1.0 0.9841538774815024 19 Q8TAA9,P21281,Q9UHX1,Q9ULK5 4 +Facial capillary hemangioma 0.85239279055314 0.8670110591487256 0.385935950255142 1.0 0.9841538774815024 2 P16435 1 +Broad alveolar ridges 0.8523927905531394 0.8670110591487223 0.3859359502551438 1.0 0.9841538774815024 2 P21281 1 +Ureteropelvic junction obstruction 0.8523927905531392 0.8670110591487215 0.3859359502551442 1.0 0.9841538774815024 2 Q9Y2B2 1 +Abnormal femoral neck morphology 0.4071458088097727 0.8666641003640569 0.3861260808063809 1.0 0.9841538774815024 36 P16278,O75844,Q7RTS9,O75718,P50542,Q9Y619,Q96A33,P04066,P51812,Q96HY6,O75431,O95831,Q9NUQ7,Q9Y487 14 +Abnormality of the intrinsic pathway 0.4546599900469943 0.8651761329563104 0.3869421230410634 1.0 0.9841538774815024 12 Q9BV10,P38435 2 +Decreased adenosylcobalamin 0.8514605344934747 0.8637451209892414 0.3877279209768707 1.0 0.9841538774815024 2 Q96EY8 1 +Decreased methylmalonyl coa mutase activity 0.8514605344934747 0.8637451209892414 0.3877279209768707 1.0 0.9841538774815024 2 Q96EY8 1 +Posteriorly rotated ears 0.3255093532797554 0.8617794601374846 0.388808889825754 1.0 0.9843637034593749 109 P56589,Q4J6C6,P42892,P04062,Q9Y619,O60566,Q15392,Q9Y4P3,P23786,Q8NCH0,Q7LGA3,O75419,Q96J42,P98175,Q10713,Q9HC07,P16435,Q9UBM7,Q9UHX1,Q9Y5Y5,O96028,O43505,O75381,O43924,Q9H490 25 +Abnormal lower limb bone morphology 0.3629447349906843 0.8604279131033784 0.3895532045892995 1.0 0.9843637034593749 163 Q15125,P21281,P04062,Q9Y619,Q96A33,Q15392,Q13509,P51798,P06280,P00813,O75844,Q7LGA3,P04066,O75419,Q96J42,Q9BV10,O95831,Q14739,Q13510,P98175,Q9Y487,Q9Y2B2,P07602,Q10713,Q7RTS9,P51812,P13073,P10644,O75845,P16435,Q9UBM7,Q9UHX1,P21964,Q03164,O96028,Q9NZJ7,O00192,O43175,O43505,O43924 40 +Abnormal autonomic nervous system physiology 0.4057491301373358 0.8549730139071767 0.3925660875572125 1.0 0.9843637034593749 33 P42892,P07602,P06280,Q9NZJ7,Q15067,P04062,O76024,Q13509 8 +Abnormality of the clitoris 0.4010654842045837 0.854325653937254 0.3929245767120846 1.0 0.9843637034593749 24 P56589,Q9Y5Y5,Q9NX14,Q9Y619,O75419,P53701,O75381,Q9UBM7,P16435 9 +Head tremor 0.4466276749272621 0.8508238629219927 0.3948672037585599 1.0 0.9843637034593749 13 P35637,Q99720 2 +Fatigable weakness of respiratory muscles 0.4334484364242303 0.8463435317160991 0.397361129922015 1.0 0.9843637034593749 15 Q7LG56,Q92804,P35637 3 +Developmental regression 0.3396880294815996 0.8461114473472378 0.3974905753166471 1.0 0.9843637034593749 130 Q86SQ9,P03886,O95470,Q9NZ08,P00846,P06280,O75306,O95831,Q9H9P8,P55795,Q13510,O76024,P07602,Q15067,O75503,P13073,O14773,Q8NI60,Q9Y5Y5,Q9NZJ7,Q9H2C2 21 +Hypercholesterolemia 0.4458143694060686 0.8457310555622326 0.3977027943672038 1.0 0.9843637034593749 13 Q15904,Q13045,Q8N511,O75431,O15120,P38571,Q9UJS0 7 +Myoclonic absence seizure 0.8458669981354805 0.8442088622932022 0.3985527031402953 1.0 0.9843637034593749 2 Q86SQ9 1 +Abnormal central sensory function 0.7128577033047465 0.8404174327922078 0.4006743781573807 1.0 0.9843637034593749 3 P33897 1 +Arthralgia 0.403084523183198 0.8397685013039763 0.4010381975940857 1.0 0.9843637034593749 30 Q9Y4P3,P28070,Q9NZ08,Q13510,Q15800,P06280 6 +Mesomelia 0.527908553766903 0.8388558749741021 0.4015501914793327 1.0 0.9843637034593749 6 Q14739 1 +Calvarial hyperostosis 0.5978123030698339 0.8377461397333351 0.4021732940135547 1.0 0.9843637034593749 4 P10644 1 +Ectodermal dysplasia 0.8436917339962721 0.8366396342582801 0.4027951601001152 1.0 0.9843637034593749 2 P21281 1 +Ankle clonus 0.4180328095257433 0.8362559666415845 0.4030109192589715 1.0 0.9843637034593749 17 P07602,O75298,Q9NZJ7,Q9NW15,P33897,Q9C0D9 6 +Muscle spasm 0.3760754245654077 0.835878307334873 0.4032233672055318 1.0 0.9843637034593749 60 Q7LG56,P35637,O75298,Q92804,P23786,Q9H6K4,P05023,P04062,P12235,P49748,Q9NR77,O43175,Q15165,P07196,P00846,P06280 16 +Urinary urgency 0.4842923515829243 0.8355118334150502 0.403429587065085 1.0 0.9843637034593749 9 P04062,O75298 2 +Abnormal metatarsal morphology 0.3994649218534866 0.8352739679681788 0.403563470985893 1.0 0.9843637034593749 25 O96028,Q7RTS9,O43505,P10644,P16435,Q15392,Q13509 7 +Aplasia hypoplasia of the lungs 0.4033262682457729 0.8352160010984554 0.4035961020000587 1.0 0.9843637034593749 33 O96028,O75844,O75419,O43175,Q14739,Q16134,P98175,Q8TAA9 8 +Premature skin wrinkling 0.3940263092750029 0.8333720467407504 0.4046349347408018 1.0 0.9843637034593749 20 O75844,P11166,Q9Y487 3 +Psoriasiform dermatitis 0.841827221876923 0.8301646560262238 0.406445695317537 1.0 0.9843637034593749 2 Q15800 1 +Abnormality of cranial sutures 0.3068878323114807 0.8248724461205169 0.4094440110650257 1.0 0.9843637034593749 82 P51798,P21964,P21281,O15047,O75844,O75718,Q8NCH0,Q9Y619,O75419,P51812,O00192,O75845,O95831,O75381,P98175,P16435,Q9NX62,Q9Y487 18 +Abnormal astrocyte morphology 0.4424441878515516 0.8246423888618867 0.4095746483252254 1.0 0.9843637034593749 13 P00846 1 +Abnormal basal ganglia mri signal intensity 0.4013331584235392 0.8228474343912416 0.4105947582813041 1.0 0.9843637034593749 31 O75306,Q8NI60,P03886,P00846,Q96CU9 5 +Spastic tetraparesis 0.4003578292361743 0.82158411992797 0.4113136302737141 1.0 0.9843637034593749 29 P07602,Q9NZJ7,Q7RTS9,P17900,P33897,Q9H9P8,P00846,Q96B26 8 +Abnormal gallbladder morphology 0.4003518578171305 0.8215367023709704 0.4113406271307647 1.0 0.9843637034593749 29 Q9Y4P3,P07602,Q9NZJ7,P04062,Q96A33,O75845,P21964 7 +Acute coronary syndrome 0.4157788283989901 0.8206478009703367 0.411846911604663 1.0 0.9843637034593749 17 O75844,Q9NZ08,P06280 3 +Abnormality of the bladder 0.3254759961988657 0.8188672143456857 0.4128621772448932 1.0 0.9843637034593749 113 Q86XL3,P35637,Q9BRK0,P04062,Q8TAA9,Q9Y4P3,P22626,Q8NCH0,O75419,P07196,O76024,Q99720,Q9NWM8,P07602,O75298,P51812,P16435,P21964,Q9UHX1,Q9NZJ7,P12235,O00192,P11166,Q9NR77,Q7LG56,Q9ULK5 26 +Poor appetite 0.4469590835379205 0.8180737468426957 0.413315078562583 1.0 0.9843637034593749 12 Q5HYI8,Q70HW3 2 +Synostosis of metacarpals metatarsals 0.7064619812007655 0.8175877788701359 0.4135926082162131 1.0 0.9843637034593749 3 P16435 1 +Thin eyebrow 0.428987341496016 0.8170352340963519 0.4139082929578173 1.0 0.9843637034593749 15 Q15125,P48449,Q96EK5 3 +Hypoplastic labia majora 0.4518821359907231 0.8164593049154851 0.4142374896085803 1.0 0.9843637034593749 11 Q9Y619,O75419 2 +Abnormal labia majora morphology 0.4518821359907231 0.8164593049154851 0.4142374896085803 1.0 0.9843637034593749 11 Q9Y619,O75419 2 +Decreased number of peripheral myelinated nerve fibers 0.40762096817942 0.8155306354615607 0.4147686359646152 1.0 0.9843637034593749 18 Q7LG56,Q9NR77,O15269 3 +Episodic pain 0.4464482212974728 0.8149536940507939 0.4150988164628659 1.0 0.9843637034593749 12 P23786,Q13423 2 +Abnormal brainstem morphology 0.3052664561907884 0.8144161386466103 0.4154065963019118 1.0 0.9843637034593749 87 O75306,O43676,Q10713,Q96EK5,P03886,Q86Y39,O43505,Q9NPL8,O95831,Q96CU9,Q13509 11 +Irritability 0.3385224967031647 0.809630363876331 0.4181526513952376 1.0 0.9843637034593749 73 P07602,Q9NZJ7,Q9BW27,Q15067,Q5BJH7,O43175,O95831,Q9NZ08,P00846,Q13510,P50897 11 +Osteomyelitis 0.4278532341272021 0.8095921992552664 0.4181745929511722 1.0 0.9843637034593749 15 P51798,Q13126 2 +Multiple rows of eyelashes 0.7040721168790838 0.8090894731304641 0.4184636829017845 1.0 0.9843637034593749 3 Q9Y606,Q9Y2Z4 2 +Thickened calvaria 0.5073326555555243 0.8087154555405588 0.4186788360033646 1.0 0.9843637034593749 7 Q7RTS9,P48651,P16278,P51812 4 +Butterfly vertebrae 0.5904304175412276 0.8079553275218159 0.4191162991435395 1.0 0.9843637034593749 4 Q9BV10 1 +Aplasia hypoplasia involving the sinuses 0.5900866948223797 0.8065723379338826 0.4199129161145345 1.0 0.9843637034593749 4 P04066 1 +Noncompaction cardiomyopathy 0.7029051867197829 0.8049465175200444 0.4208505432112195 1.0 0.9843637034593749 3 P21912 1 +Inappropriate behavior 0.4331025267373171 0.8030126089252763 0.4219674467476531 1.0 0.9843637034593749 14 P07602,O43175,Q9NZJ7 3 +Abnormal sternal ossification 0.5891065381932669 0.8026307326687383 0.4221881996413787 1.0 0.9843637034593749 4 Q9Y619 1 +Ulnar deviation of the wrist 0.5887608349683063 0.8012412734607757 0.4229919814367422 1.0 0.9843637034593749 4 P16435,Q9BV10 2 +Neoplasm of the male external genitalia 0.490898468329184 0.8006017397562921 0.4233622432413462 1.0 0.9843637034593749 8 Q13423,Q01844,O96017,P10644 4 +Aplasia hypoplasia of the femur 0.4198556029931233 0.8005192432624786 0.4234100188815379 1.0 0.9843637034593749 16 Q9UHX1,O95831 2 +Intracranial hemorrhage 0.3920513509065865 0.8005061994106517 0.4234175731686931 1.0 0.9843637034593749 22 P23786,O75844,P04062 3 +Aplasia hypoplasia of the tongue 0.5411555942306867 0.8003257893734922 0.4235220649070261 1.0 0.9843637034593749 5 P48651,Q96J42,Q9UBM7 3 +Bilateral ptosis 0.4196161718843949 0.7989079859513268 0.4243437679767634 1.0 0.9843637034593749 16 O75306,Q7LG56,Q13509 3 +Abnormality of the brainstem white matter 0.5880552713162686 0.7984066837650244 0.4246345258760913 1.0 0.9843637034593749 4 Q10713 1 +Abnormal blood sodium concentration 0.4774187386181882 0.798267353064033 0.4247153590864885 1.0 0.9843637034593749 9 Q13423 1 +Progressive cerebellar ataxia 0.3986409083416233 0.7958827691676208 0.4261001772991581 1.0 0.9843637034593749 36 O75306,Q8NI60,P35637,Q9Y619,O14773,Q96CU9,O76024,Q9Y487 8 +Hypoplasia of the odontoid process 0.5046240467198384 0.7953903707149985 0.4263864595226598 1.0 0.9843637034593749 7 Q7RTS9,P16278,O95831 3 +Acetabular dysplasia 0.4627720914372606 0.7938717224803801 0.4272701132375545 1.0 0.9843637034593749 10 Q9Y584,P16278,Q969X5 3 +Weakness of muscles of respiration 0.3982372386138934 0.793759754333866 0.4273353061891425 1.0 0.9843637034593749 33 P22626,Q7RTS9,Q15067,P10253,P12235,O95831,Q7LG56,Q13510 8 +Increased ldl cholesterol concentration 0.4765320016772766 0.7934715561822636 0.4275031349219587 1.0 0.9843637034593749 9 P38571,Q8N511,P50402,Q9UJS0 4 +Hyperlipoproteinemia 0.4765320016772766 0.7934715561822636 0.4275031349219587 1.0 0.9843637034593749 9 P38571,Q8N511,P50402,Q9UJS0 4 +Urinary glycosaminoglycan excretion 0.5180932180170855 0.7927650343396111 0.4279147318098188 1.0 0.9843637034593749 6 P54802,P04066,P16278 3 +Abnormality of the calcaneus 0.47622100993902 0.7917901219332562 0.4284830630280918 1.0 0.9843637034593749 9 Q14739,O43175 2 +Abnormality of the supraorbital ridges 0.393732388600324 0.7908307335297946 0.4290427728857917 1.0 0.9850735825704434 25 P56589,Q9Y5Y5,P50542,P51812,Q6NUK1,O75381,P98175,P16435 8 +Fasting hyperinsulinemia 0.5859845190176899 0.7900971387538985 0.4294710407374638 1.0 0.985095264570331 4 Q16836,P00367 2 +Vertebral compression fracture 0.4246882637866588 0.7888396751080125 0.4302057173588447 1.0 0.985095264570331 15 Q96HY6,P04062,Q14108 3 +Nephrotic syndrome 0.3956522974287486 0.7887060151136099 0.430283851457705 1.0 0.985095264570331 28 P06280,Q14108,Q9BW27,Q8NCH0,O95470,Q9BT22 6 +Pancreatitis 0.3892360083738985 0.7878492663267641 0.4307848797449731 1.0 0.985095264570331 21 P03886 1 +Fasciculations 0.3974516628667461 0.7869496082545783 0.4313113656019969 1.0 0.985095264570331 37 P22626,P07602,P35637,Q9NZJ7,Q9BQT8,O95831,Q13510,P06280 8 +Hyperglycemia 0.4879796648072596 0.7855241548323899 0.4321463137553902 1.0 0.9862520017724168 8 O75844 1 +Sparse and thin eyebrow 0.4414617209164418 0.7845348033554521 0.4327263685919453 1.0 0.9865902086310372 12 Q15125,Q96EK5 2 +Spastic paraplegia 0.3804484896450076 0.7829156146577161 0.43367666743096 1.0 0.987645112554562 55 O75306,O75298,Q9BRK0,O00400,P04062,Q7KZN9,Q9Y619,P11166,Q15041,O95831,P00846,Q96CU9,Q9C0D9 13 +Spinal cord lesion 0.5017324927945624 0.7811890799575186 0.4346912953858326 1.0 0.987645112554562 7 O00400 1 +Decreased specific antibody response to protein vaccine 0.6959900528442307 0.7804881485696997 0.435103600718373 1.0 0.987645112554562 3 Q13546,Q9BV10 2 +Progressive hearing impairment 0.4404779037266554 0.7785415564198614 0.4362498178976208 1.0 0.987645112554562 12 P03886,O60313,P49736,P00403,O76024 5 +Bone cyst 0.6950575069940796 0.7772022767653517 0.4370394391756931 1.0 0.987645112554562 3 P21912,Q99643 2 +Abnormality of the nasal tip 0.3078636778040767 0.7727796705942822 0.4396527866872202 1.0 0.9914973259496096 94 P42892,P21281,Q96EK5,Q96A33,O75844,P23786,Q7LGA3,O95831,Q9Y487,Q9Y2B2,P51812,P10644,O75845,O43292,P16435,P21964,Q9UHX1,Q03164,Q02252,O43924 20 +Melanocytic nevus 0.4439532333954514 0.769186402518669 0.4417826613275859 1.0 0.9923840900216632 11 P21912,P10644,Q99643 3 +Metaphyseal dysplasia 0.4388394051229998 0.7685667015011816 0.4421505793678051 1.0 0.9923840900216632 12 Q7RTS9,Q9NUQ7,Q9HC07,O95831 4 +Insulin resistance 0.3932291067950285 0.76723904369966 0.4429394030481817 1.0 0.9923840900216632 19 O75844,P31751 2 +Decreased number of large peripheral myelinated nerve fibers 0.5124569625225963 0.7664285470731151 0.4434213522799313 1.0 0.9923840900216632 6 Q7LG56,O15269 2 +Aplasia hypoplasia of toe 0.3943607640474801 0.7642106951927251 0.4447416940333468 1.0 0.9923840900216632 32 Q03164,P00813,O96028,Q7LGA3,P13073,P10644,Q13510,Q9UBM7,Q9UHX1 9 +Multicystic kidney dysplasia 0.3859898661580615 0.763266520113882 0.445304464537801 1.0 0.9923840900216632 21 P56589,Q9Y5Y5,Q10713,Q96J42,O75381,Q9UBM7,O60566 7 +Abnormality of the calf 0.3748301619347396 0.7620550527046173 0.4460271474278436 1.0 0.9923840900216632 57 Q9Y4P3,P51798,P16278,Q7RTS9,O75718,Q7LGA3,Q9Y619,Q13126,O75419,Q96HY6,Q9NR77,O75431,Q9BV10,O95831,P16435,Q9NX62,Q13509 17 +Abnormality of the fontanelles or cranial sutures 0.3154879834263731 0.7615229420619454 0.4463447811325274 1.0 0.9923840900216632 105 P56589,Q15125,P21281,O75718,Q9Y619,Q9NX62,Q9BT22,P51798,O75844,Q8NCH0,O75419,O75431,O95831,P98175,Q9Y487,O15047,P51812,O75845,P16435,P21964,Q9Y5Y5,O00192,O75381,Q16134 24 +Pelvic kidney 0.4701580112454096 0.7590672415006668 0.4478123340175821 1.0 0.9946789276258302 9 Q9UHX1 1 +Abnormal exteroceptive sensation 0.3810430965176318 0.7579095150133477 0.4485051536882709 1.0 0.9950718207065348 53 P07602,Q7LG56,P07196,Q9NZJ7,Q9H6K4,Q8NCH0,O15269,P54802,Q9NR77,O95831,Q9NZ08,P06280 12 +Abnormality of circulating glucocorticoid level 0.4414251975581177 0.7541533274658734 0.4507571591451875 1.0 0.9950718207065348 11 Q13423,P10644,P33897,P16435 4 +Fetal onset 0.5097121499052815 0.7536414619481543 0.4510645407326323 1.0 0.9951298341899552 6 Q9P0S2 1 +Congenital onset 0.3148128109454447 0.7518606896784314 0.4521348403533458 1.0 0.9970096938100566 105 Q4J6C6,Q15125,Q9NQT5,Q96EK5,P21281,P50542,Q9HC21,Q9BUB7,Q13509,Q7LGA3,Q99757,P08670,Q96N66,P07602,Q9BW92,P42356,Q9NX14,P51571,Q9UHX1,Q9NZJ7,P12235,Q6NUK1,P46977,Q8NFH4,O43505,Q5XKP0,Q969X5,Q5BJH7,O43924 29 +Neoplasm of the small intestine 0.508782505122853 0.7493166445523298 0.4536663780168974 1.0 0.997999068248559 6 Q99643 1 +Hypermetric saccades 0.6868954824573681 0.748576482627316 0.4541125110283988 1.0 0.997999068248559 3 O14773 1 +Upper limb postural tremor 0.6866645943425274 0.7477703061448866 0.4545987156662276 1.0 0.9981074156073976 3 P04350,Q9NR77 2 +Meningioma 0.5082912378013975 0.7470324802358989 0.455043955067175 1.0 0.9981256988487386 6 P21912,Q99643 2 +Abnormal femoral neck head morphology 0.3894610995907612 0.7444088399055175 0.4566291726293059 1.0 0.9984873768123456 44 P16278,O75844,Q7RTS9,O75718,Q7LGA3,P50542,Q9Y619,Q96A33,P04066,P51812,Q96HY6,O75431,O95831,Q14739,Q9NUQ7,Q9Y487 16 +Increased urine alpha ketoglutarate concentration 0.5077120008076675 0.7443404387818569 0.4566705424273061 1.0 0.9984873768123456 6 Q9P0S2,P21281 2 +Tissue ischemia 0.3897223189868002 0.7416469817673415 0.4583012502852583 1.0 0.9984873768123456 19 Q9NZ08,O75844,P06280 3 +Occipital encephalocele 0.5737560208622114 0.7413407302153391 0.4584868716463779 1.0 0.9984873768123456 4 Q10713 1 +Abnormal circulating carboxylic acid concentration 0.3056001957910421 0.7401864022619666 0.4591868972330934 1.0 0.9985585519483816 94 Q99797,P03886,Q9Y619,Q9P0S2,Q9BUB7,P00846,O75208,P23786,Q9NP80,Q9H9P8,Q14739,Q96EY8,O75845,Q9H3L0,O43175,Q5XKP0,P22695,Q7LG56,Q16134,Q9NSD9 20 +Abnormality of the coagulation cascade 0.3906073717757289 0.7391964333938379 0.4597877262692025 1.0 0.9985585519483816 41 P38435,Q9Y619,Q9P0S2,Q5XKP0,Q9BV10,Q9Y487 6 +Aplasia hypoplasia of the skin 0.3774296136277988 0.7376863614334734 0.4607050618312953 1.0 0.9985585519483816 54 Q9NWM8,Q15125,O96028,O75844,Q8NCH0,Q9Y619,Q13126,P10644,P53701,Q15392 10 +Abnormality of pancreas physiology 0.390333474544333 0.7368372632493819 0.4612213194851586 1.0 0.998835906375039 41 Q9NZ08,Q14739,Q9UHX1,P03886 4 +Ovotestis 0.8138595400869986 0.7346107824251293 0.4625765693873034 1.0 0.998835906375039 2 P53701 1 +Weak voice 0.5253073400336578 0.7308561908680492 0.4648669973888331 1.0 0.998835906375039 5 O75787,P04062 2 +Abnormality of the basal ganglia 0.2985836590002036 0.7291801711559734 0.4658914588632954 1.0 0.9989010209039872 86 Q96N66,Q8NI60,O75306,P03886,P23786,P04062,Q9NZ01,O95831,P00846,Q96CU9,Q13509 11 +Gastroesophageal reflux 0.3277293643305131 0.7270372618598532 0.4672031297307992 1.0 0.999659953483997 125 Q86SQ9,P21281,Q9Y619,Q96A33,Q01105,P00846,Q9Y4P3,O15269,Q9Y584,P49748,Q8IZA0,Q9BV10,Q14739,P55795,P07602,P51571,P16435,Q9UBM7,P21964,Q9UHX1,Q03164,O96028,Q9NZJ7,Q9H2C2,P12235,O43175,Q7LG56,Q9NSD9 28 +Hyperkalemia 0.5036577234548562 0.7255335352313398 0.4681247793122385 1.0 0.999659953483997 6 Q13423 1 +Multiple prenatal fractures 0.5032514729683686 0.7236525643817004 0.4692790619825335 1.0 0.999659953483997 6 Q14739 1 +Paraplegia 0.3706882052769003 0.720576595594498 0.471170057898151 1.0 0.999659953483997 57 O75306,O75298,Q9BRK0,O00400,P04062,Q7KZN9,Q9Y619,P11166,Q15041,O95831,P00846,Q96CU9,Q9C0D9 13 +Dilatation of the cerebral artery 0.4497705716194825 0.7203985245317239 0.4712796582061047 1.0 0.999659953483997 10 P10644,P10253,P38435 3 +Preaxial hand polydactyly 0.4355407110408595 0.7192479319484455 0.4719881711010187 1.0 0.999659953483997 11 O43909,Q96J42,O96028,Q9UHX1 4 +Cerebral hemorrhage 0.4353883421082146 0.7183458672364216 0.4725440555237439 1.0 0.999659953483997 11 P23786,P21912,Q99643 3 +Hypoplasia of the uterus 0.4618391864188653 0.714372128139875 0.4749971019946941 1.0 0.999659953483997 9 Q16740 1 +Absent nipple 0.806712243629586 0.7107141979677531 0.4772613596381774 1.0 0.9997295161416468 2 P10586 1 +Congenital craniofacial dysostosis 0.8067122436295786 0.7107141979677277 0.4772613596381931 1.0 0.9997295161416468 2 P10644 1 +Difficulty walking 0.3135890065656729 0.7084296835574706 0.4786784643568857 1.0 1.0 78 Q86SQ9,P07602,P35637,O75298,Q9NZJ7,Q7RTS9,Q9H2C2,Q15067,O43292,Q9NR77,O14653,Q15041,O14773,P00846,Q15907,Q13510,Q99720 17 +Encephalopathy 0.3160128149159043 0.7050272554310489 0.4807932747771837 1.0 1.0 111 O43676,Q86SQ9,P03886,P04062,Q9Y619,Q9P0S2,Q9NVI7,Q96CU9,O75306,O75208,P23786,Q86Y39,Q9NPL8,P07602,Q15067,Q7KZN9,Q9Y6M9,Q9NZJ7,Q9H2C2 19 +Abnormal pigmentation of the oral mucosa 0.8048477315102573 0.7045188038893386 0.4811097440158569 1.0 1.0 2 O75431 1 +Tetraplegia tetraparesis 0.3765585125604934 0.701569194918749 0.4829478682996733 1.0 1.0 52 Q13423,P07602,P35637,Q9UBX3,Q7RTS9,Q9NZJ7,P51572,P17900,P33897,O95831,Q9H9P8,P00846,Q9C0D9,Q96B26 14 +Conjunctival hamartoma 0.8036047234306937 0.7003976227312093 0.483679020483831 1.0 1.0 2 Q99643 1 +Glomus jugular tumor 0.8036047234306937 0.7003976227312093 0.483679020483831 1.0 1.0 2 Q99643 1 +Abnormality of retinal pigmentation 0.3231325167020098 0.6992289215417363 0.4844089789428718 1.0 1.0 75 P56589,Q86SQ9,P03886,P50542,P53701,P00846,Q96CU9,O75306,Q15555,P51648,O76024,Q9C0D9,Q15067,Q7KZN9,P51812,Q9NX14,Q9Y5Y5,O75251,P21912,Q7LG56,O75381,Q9UG56 22 +Mortality aging 0.3130634166335413 0.6947140901511267 0.4872344961005996 1.0 1.0 108 P56589,P05067,O75718,P04062,Q9P0S2,Q9HC21,Q9NVI7,Q9BUB7,Q9BT22,Q9Y4P3,O75844,P49748,Q9NPL8,O75431,Q14739,P07602,Q15067,P51812,Q9NX14,P16435,Q9Y5Y5,P16278,Q9NZJ7,Q6PJG6,Q6NUK1,Q96IX5,O43175,O75381,Q16134 29 +Vertebral hypoplasia 0.4450972192117487 0.6941418235836257 0.4875932721789053 1.0 1.0 10 Q14739,Q96HY6,Q8TAA9,P10644 4 +Lymphedema 0.4213122548725393 0.6931811300443713 0.4881958886535231 1.0 1.0 13 Q14739 1 +Ectrodactyly 0.4156224529996363 0.6917160585792526 0.4891156602502871 1.0 1.0 14 P48449,O96028,Q9NR77,P07196,Q99720 5 +Proximal symphalangism 0.6704065879332093 0.6915409143620403 0.4892256781852848 1.0 1.0 3 P48651 1 +Symphalangism affecting the phalanges of the hand 0.6704065879332093 0.6915409143620403 0.4892256781852848 1.0 1.0 3 P48651 1 +Brittle hair 0.4034283804483811 0.6904542850967196 0.4899085488969799 1.0 1.0 16 O75844,Q9Y487 2 +Finger agnosia 0.8004972032318238 0.6901269524134589 0.4901143551299673 1.0 1.0 2 O96008 1 +Deposits immunoreactive to beta amyloid protein 0.8004972032318238 0.6901269524134589 0.4901143551299673 1.0 1.0 2 O96008 1 +Cerebral amyloid angiopathy 0.8004972032317991 0.6901269524133784 0.490114355130018 1.0 1.0 2 Q9Y287 1 +Dyskinesia 0.3429998509883986 0.6871859985267408 0.4919655264177343 1.0 1.0 68 O75306,Q86SQ9,Q96N66,P03886,Q9UBX3,Q9H2C2,P04062,P35610,Q9NZ01,P00846,Q5BJH7 11 +Thoracic hypoplasia 0.3829587094796578 0.683947062800519 0.494008594169129 1.0 1.0 29 P51798,P04062,Q96A33,Q96HY6,Q14739,P16435,Q9UHX1 7 +Abnormal lung development 0.3811324142157801 0.6839369711475684 0.494014966905492 1.0 1.0 46 P21964,O96028,O75844,O75419,O00192,O43175,Q14739,Q16134,Q9UBM7,P98175,Q8TAA9,Q9UHX1 12 +Cupped ear 0.4247991393481717 0.6834954678709012 0.494293813042741 1.0 1.0 12 Q15392 1 +Contractures of the large joints 0.7973896830329426 0.6799032591875174 0.496565717832115 1.0 1.0 2 O75431 1 +Irregular capital femoral epiphysis 0.7973896830329426 0.6799032591875174 0.496565717832115 1.0 1.0 2 Q9NUQ7 1 +Optic nerve dysplasia 0.7973896830329219 0.6799032591874493 0.4965657178321581 1.0 1.0 2 O43505 1 +Gangrene 0.4551817354204376 0.678802160088851 0.4972632249431319 1.0 1.0 9 Q9NZ08 1 +Progressive spastic paraplegia 0.3822863358283648 0.6741776000544855 0.5001984088870728 1.0 1.0 30 O75306,O00400,Q7KZN9,P00846,Q96CU9,Q9C0D9 6 +Supraventricular arrhythmia 0.4068965798463431 0.6728640018746781 0.501033815715985 1.0 1.0 15 Q7LG56,P00846,P12235 3 +Gliosis 0.383045862787631 0.671218764304734 0.5020811766126247 1.0 1.0 40 O75306,Q10713,P35637,P04062,Q9H9P8,P00846,Q16134 7 +Subcutaneous hemorrhage 0.3829167431716472 0.6656315483268921 0.5056466361923888 1.0 1.0 36 P51798,Q9NWM8,Q14108,P38435,Q8NCH0,P04062,Q13126,P10644 8 +Frequent falls 0.3815005659751044 0.6645686024054858 0.5063264568805155 1.0 1.0 42 P07602,Q9NZJ7,Q7RTS9,P04062,P12235,Q9NR77,P00846,Q13510 8 +Nasal regurgitation 0.6624184022381012 0.664331962200326 0.5064778685512035 1.0 1.0 3 Q13472,P53007 2 +Abnormal platelet volume 0.4523346150194535 0.6636516722822099 0.5069132772499603 1.0 1.0 9 Q14739 1 +Decreased plasma carnitine 0.4213108701524532 0.6624937906950027 0.5076548129373311 1.0 1.0 12 O75880,P23786,Q16836,P49748,O43772,O75648 6 +Weight loss 0.3406708997704725 0.6605810504915569 0.5088810247104567 1.0 1.0 68 Q13423,P42892,P07602,Q7LG56,P35637,Q9NZJ7,O75844,P04062,P10644,Q9NZ08,Q5HYI8,Q99643,Q99720 13 +Type ii lissencephaly 0.6612861554699789 0.6604994118361837 0.5089333958054214 1.0 1.0 3 Q13509 1 +Soft tissue sarcoma 0.3777053718957761 0.6602569169721442 0.5090889726079926 1.0 1.0 26 P10644,Q15392,Q99643,Q13126 4 +Protruding tongue 0.4388821831037072 0.6593751183052015 0.5096549158543218 1.0 1.0 10 Q10713,P67870,P42356,Q6NUK1 4 +Delayed eruption of permanent teeth 0.7905531385953983 0.6575818493386737 0.5108068608418177 1.0 1.0 2 P21281 1 +Cavernous hemangioma 0.5081070952771901 0.6566240969592084 0.5114226506808919 1.0 1.0 5 Q99643 1 +Lack of skin elasticity 0.4094881987778248 0.6529762217880084 0.5137716080558534 1.0 1.0 14 O75844,O43175,P10644 3 +Constipation 0.2979885338845141 0.6528407529145283 0.5138589478156992 1.0 1.0 92 P42892,P03886,P04062,Q8TAA9,Q9Y4P3,Q13423,Q8NCH0,Q7LGA3,P55795,O76024,Q99643,O15047,Q9UBM7,P16435,P21964,Q9Y5Y5,Q03164,P12235,Q7LG56 19 +Broad metacarpals 0.7889993784959635 0.6525424536882762 0.5140512951130425 1.0 1.0 2 P16278 1 +Cloverleaf skull 0.7889993784959523 0.6525424536882394 0.5140512951130662 1.0 1.0 2 P16435 1 +No social interaction 0.7889993784959504 0.6525424536882333 0.5140512951130702 1.0 1.0 2 Q15067 1 +Muscle fiber atrophy 0.3712120503739075 0.6519831209664468 0.5144120611939877 1.0 1.0 21 P23786,P22626,P35637,Q99720 4 +Exercise induced muscle cramps 0.4873608333581781 0.6506438525823907 0.5152764154792058 1.0 1.0 6 P23786,P53985 2 +Expressive language delay 0.4496267091066873 0.6492790318379212 0.5161580362871625 1.0 1.0 9 Q9UHX1 1 +Hepatomegaly 0.3583857191767552 0.6485406852359509 0.5166353051551664 1.0 1.0 180 P56589,O43676,Q86SQ9,P21281,P03886,O15118,P04062,Q9Y619,Q96A33,Q9HC21,P35610,P31751,Q9NVI7,Q9BUB7,P00846,Q96CU9,Q9BT22,P51798,O75306,P00813,P23786,Q86Y39,P04066,P49748,Q9NPL8,Q14739,Q13510,Q9UJW0,P00374,Q96EY8,P07602,Q10713,Q9HC07,P28070,Q15067,O43772,O75845,Q9Y6M9,Q9Y5Y5,Q14108,Q9NZJ7,P10253,P54802,P11166,Q96HY6,O75381,Q16134 47 +Abnormal cerebellar vermis morphology 0.3156318305972111 0.645609419785952 0.5185323353376015 1.0 1.0 76 Q15125,P21281,Q9HC21,Q15907,O60566,Q13509,P23786,Q96J42,Q9UHD1,P98175,Q9Y487,Q96B26,Q10713,P42356,Q9UBM7,Q9Y5Y5,Q8NFH4,O43175,O43505,O43924,Q9H490 21 +Spastic ataxia 0.4737433004744682 0.6453296187478018 0.5187136024980981 1.0 1.0 7 Q13509 1 +Hammertoe 0.376117653140632 0.6429440883774498 0.520260380165463 1.0 1.0 19 P07196,Q9NR77,Q9UBM7,Q99720 4 +Hypoparathyroidism 0.4130942558830855 0.6425644659695516 0.5205067464053195 1.0 1.0 13 P21964,P03886 2 +Fatigable weakness of swallowing muscles 0.4126848487359074 0.6400524467799587 0.5221385030199057 1.0 1.0 13 Q92804,P35637,Q15165 3 +Abnormality of the peritoneum 0.3681485452287389 0.6390911904645967 0.5227636105354179 1.0 1.0 20 Q9BW27,Q01844,Q8NFH4,Q5HYI8,Q8N1F7 5 +Severe global developmental delay 0.3151024478190342 0.6388128725968207 0.5229446731061009 1.0 1.0 76 P56589,Q9Y5Y5,P03886,Q9BT22,Q7RTS9,O75381,Q15067,Q7LGA3,Q96A33,P51812,Q9HC21,Q99757,O43175,Q9BV10,P00846,Q9H490,Q13509 17 +Abnormal circulating gaba concentration 0.7846488502175297 0.6385004759265963 0.5231479443431659 1.0 1.0 2 P05067 1 +Abnormal phalangeal joint morphology of the hand 0.3795487406731954 0.6378955883562623 0.5235416497301439 1.0 1.0 36 Q9Y2B2,O75844,Q9Y619,O75419,P16435,Q9BUB7,O76024,Q13509 8 +Diaphragmatic weakness 0.5469793915410239 0.6368126232286899 0.5242469026830412 1.0 1.0 4 Q9NR77 1 +Proximal muscle weakness 0.3481534981562669 0.6342666114955071 0.525906842409489 1.0 1.0 64 Q8NI60,P22626,Q7LG56,P35637,Q9BQT8,P10253,Q9NP80,Q13126,P12235,P07196,P00846,Q13510,Q99720 13 +Parkinsonism 0.3765318128698054 0.6334881154760145 0.5264149393486497 1.0 1.0 29 P05067,P07602,P35637,Q13057,Q9NZJ7,P04062,O96008,Q6Y7W6,Q99720 9 +Increased c peptide level 0.6524712465029536 0.6308767363644212 0.5281211239391577 1.0 1.0 3 Q16836,O15120 2 +Abnormal thyroid stimulating hormone level 0.7815413300186345 0.6285334488835898 0.5296545417497871 1.0 1.0 2 P10644 1 +Broad femoral neck 0.541156325590087 0.6145631325751297 0.5388432680733464 1.0 1.0 4 Q7RTS9,Q9NUQ7 2 +Ectopia lentis 0.4793772500633378 0.6144370537861163 0.5389265565734647 1.0 1.0 6 Q03518 1 +Cerebral hypoplasia 0.3976309798175044 0.6130952757327517 0.5398133437940902 1.0 1.0 15 O43175,Q9UBM7,Q86XL3 3 +Dermatological manifestations of systemic disorders 0.3193843287954956 0.612214104054732 0.5403961112412317 1.0 1.0 74 Q9Y5Y5,O15118,O75844,O75381,Q16134,P04066,P51812,P49748,O43772,P11166,P10644,Q14739,Q5HYI8,P98175,P00374 15 +Retinal dystrophy 0.3561909650663998 0.610773117359798 0.5413497927218689 1.0 1.0 59 Q9Y287,Q86SQ9,Q10713,Q9Y5Y5,P38435,P03886,Q15067,Q9H2C2,O43505,P53701,P00846 11 +Parkinsonism with favorable response to dopaminergic medication 0.4299291201879678 0.609644711492008 0.5420971866056163 1.0 1.0 10 P07602,P04062 2 +Recurrent fever 0.4023620956939501 0.608244926649631 0.5430250416509415 1.0 1.0 14 Q5T440,P28070,P51572,Q13546,Q9NR77,Q13510 6 +Everted upper lip vermilion 0.5392199273661172 0.6072074328543062 0.5437132601242707 1.0 1.0 4 P04062 1 +Abnormality of earlobe 0.3687368541729547 0.6066358349718809 0.5440926132287021 1.0 1.0 24 Q7LGA3,O00192,P16435,P53701,P10586,P98175,Q15392,P21964 8 +Abnormal head movements 0.4070918388952586 0.6058376203729023 0.5446225854687454 1.0 1.0 13 P35637,Q99720 2 +Abnormal mitral valve physiology 0.3753093618605465 0.604177669328158 0.5457255257097695 1.0 1.0 35 O75306,Q9Y4P3,O75844,P04062,P51812,O75431,P53701,Q9NZ08,P06280 9 +Progressive 0.3101882603111651 0.6010644941598481 0.5477970308540856 1.0 1.0 113 Q9NR28,Q12769,P04062,P27544,O14653,O95470,Q9UHD9,Q5T440,O00400,Q9NP80,Q13126,Q99757,O95831,Q13510,Q16637,Q99720,O75298,Q13057,Q9Y6M9,Q8N1F7,Q9Y5Y5,O75251,Q6PJG6,Q9BW27,P12235,P54802,P33897,Q5XKP0,Q7LG56 29 +Heterogeneous 0.3740932215234498 0.6007227509083719 0.5480246631978067 1.0 1.0 42 P51798,P03886,O75844,Q9Y619,P12235,Q9BQE5,P00846 7 +Abnormal heart valve morphology 0.3152159419462171 0.5991765679332215 0.5490551466711979 1.0 1.0 75 P04062,Q9BUB7,P53701,P06280,Q9Y4P3,P51798,O75844,Q8NCH0,O75431,P55795,Q9Y2B2,P51812,P10644,Q9NX14,P21964,Q9UHX1,O96028,P16278,O00192 19 +Absent epiphyses 0.4513551958055498 0.5991072483860033 0.5491013684027419 1.0 1.0 8 Q7RTS9,Q8WVQ1,O43909,Q7LGA3 4 +Abnormality of the vertebral endplates 0.4638785045063727 0.5983322967351082 0.5496182307518447 1.0 1.0 7 P51798,Q7RTS9 2 +Retinal thinning 0.7719080174020894 0.5979823540064416 0.5498517073989813 1.0 1.0 2 P51648 1 +Abnormality of the autonomic nervous system 0.3615050257518017 0.5976814026484831 0.5500525368042708 1.0 1.0 55 Q13509,Q9Y2B2,P42892,P07602,Q10713,P21964,Q96EK5,Q9NZJ7,Q6PJG6,Q15067,P04062,O15269,O00192,Q99757,Q9UBM7,O76024,Q6Y7W6,P06280 18 +Amyloidosis 0.6421478081199499 0.5966972014715393 0.5507095613738535 1.0 1.0 3 Q9Y287 1 +Kinetic tremor 0.373969564133599 0.595100245217967 0.5517764647488352 1.0 1.0 34 Q9Y287,P07602,Q14108,Q9NZJ7,O75027 5 +Limb myoclonus 0.4631936985420293 0.5950908064835264 0.5517827736480636 1.0 1.0 7 P11166,Q13510 2 +Abnormal meningeal morphology 0.3660523796918913 0.5948604970300966 0.551936724666104 1.0 1.0 23 P21964,Q10713,O75845,Q9ULK5,Q8TAA9,Q9UHX1 6 +Nyctalopia 0.373501006817287 0.593795830385297 0.5526486782038358 1.0 1.0 33 P56589,Q9Y287,Q86SQ9,Q10713,Q9Y5Y5,P38435,Q15555,O75381 8 +Ventricular arrhythmia 0.3741966889698449 0.593690774412174 0.5527189546277045 1.0 1.0 38 O75306,P42892,P03886,P23786,P10253,P12235,P49748,O43772,Q7LG56,P00846,Q99643 11 +Orthostatic hypotension 0.4048915139924187 0.5924330490272532 0.5535606410354514 1.0 1.0 13 P07602,P04062 2 +Breech presentation 0.4385369672680535 0.5908384933498277 0.5546286405232013 1.0 1.0 9 O75718,Q9UBM7,Q9Y619,Q969X5 4 +Abnormal blood inorganic cation concentration 0.3736000507679811 0.5891012069157577 0.5557933838339228 1.0 1.0 36 Q9Y4P3,P51798,P21964,P05023,O00192,P49748,P10644,Q9BV10,Q99643,Q9NSD9 10 +Bowing of the legs 0.3683176368830602 0.5838760337146364 0.5593037185583487 1.0 1.0 48 Q9Y4P3,P51798,P16278,Q7RTS9,O75718,Q7LGA3,Q9Y619,Q13126,O75419,Q96HY6,Q9NR77,O75431,P16435,Q9NX62,Q13509 15 +Supernumerary bones of the axial skeleton 0.4905273652157947 0.5823401963809338 0.5603375551951877 1.0 1.0 5 Q9UHX1 1 +2 3 toe syndactyly 0.3674959515538573 0.5819352806203999 0.560610275164781 1.0 1.0 26 Q15125,P51812,O75419,O43924,Q9UHX1 5 +Cupped ribs 0.4721286819842973 0.5818826701998099 0.5606457141974208 1.0 1.0 6 O95831 1 +Humeroradial synostosis 0.7663144810441134 0.5804936109023504 0.5615817940630421 1.0 1.0 2 P16435 1 +Elbow ankylosis 0.7663144810441134 0.5804936109023504 0.5615817940630421 1.0 1.0 2 P16435 1 +Abnormal oral frenulum morphology 0.4072951374302951 0.5788087968710012 0.5627181947781792 1.0 1.0 12 O75844,O43924 2 +Calvarial skull defect 0.4713891475187702 0.5785796873712601 0.5628728139576369 1.0 1.0 6 Q14739 1 +Asymmetric growth 0.4360971990529728 0.5780815877149682 0.5632090372995964 1.0 1.0 9 Q15125 1 +Psychosis 0.3693426387069128 0.5773971303447701 0.5636712123031407 1.0 1.0 29 Q9Y287,O15118,P03886,Q6DKK2,P10644,O76024 6 +Abnormal aortic arch morphology 0.4237504711372912 0.5756060205883097 0.5648815106880138 1.0 1.0 10 P21964,Q9UHX1 2 +Antenatal onset 0.4350710118752345 0.5727276748765388 0.5668290960997444 1.0 1.0 9 Q9P0S2 1 +Periportal fibrosis 0.7635177128651303 0.5718210275088198 0.5674432301594494 1.0 1.0 2 P49748 1 +Limb joint contracture 0.2998996416849215 0.5707561594597621 0.5681649445357095 1.0 1.0 102 P42892,Q86XL3,P35637,P50542,Q9Y619,Q9HC21,Q9BUB7,Q15392,Q13509,O75340,O75844,P23786,Q7LGA3,O75419,Q8IZA0,P07196,Q99720,Q9Y2B2,P16435,P50402,Q9NR77,O43175,P33897,Q969X5,Q9H4L7,P21912 26 +Dental malocclusion 0.3627956990712546 0.570446900291112 0.5683746271968921 1.0 1.0 23 Q9Y4P3,P51798,P21281,P51812,P10644 5 +Increased blood pressure 0.3247040371122762 0.5696914720606635 0.5688869751416803 1.0 1.0 71 P21964,P42892,Q10713,P06280,P03886,O75844,P04062,P35610,P10644,Q9BUB7,P16435,Q8TAA9,Q99643,Q9NSD9 14 +Abnormality of female external genitalia 0.3712176604217405 0.5689693328909298 0.5693769518986675 1.0 1.0 38 P56589,Q9Y5Y5,Q9NX14,Q9Y619,O75419,Q6NUK1,P10644,P53701,O75381,Q9UBM7,P16435,Q15392 12 +Diminished movement 0.3611027188069156 0.5669829496169401 0.5707257658104217 1.0 1.0 22 P04062,P12235,O95831 3 +Bilateral tonic clonic seizure with focal onset 0.6329846176248892 0.5668589066154143 0.5708100451935452 1.0 1.0 3 P07602 1 +Choreoathetosis 0.3704647895012352 0.5648720382759785 0.5721608038056027 1.0 1.0 35 P00846,Q9H6K4 2 +Widened subarachnoid space 0.36663529816021 0.5621619048007251 0.574005714065037 1.0 1.0 28 Q9P0S2,O95831,P03886 3 +Tachypnea 0.371346106729599 0.5604269901853707 0.5751882261157333 1.0 1.0 18 Q10713,Q9Y619,P35610,P22695,O43924,Q9NSD9 6 +Abnormal shape of the frontal region 0.2983001789456959 0.5586528086585123 0.5763986919986324 1.0 1.0 101 Q4J6C6,Q15125,P21281,Q9Y619,Q9NVI7,O60566,Q15392,P51798,P04066,Q14739,Q9Y487,Q9Y2B2,Q15067,P51812,P13073,P16435,O96028,Q02252,Q9ULK5,O43924 20 +Lambdoidal craniosynostosis 0.7591671845866845 0.5584280666320429 0.5765521118256549 1.0 1.0 2 P16435 1 +Neoplasm of the respiratory system 0.4202492211837954 0.5564320979340864 0.577915501327591 1.0 1.0 10 P04637,P02545,P30154,P52701,P49815,P43246,Q01844,O96017,Q13263 9 +Brisk reflexes 0.3627419723275146 0.5533309860147448 0.5800367869659198 1.0 1.0 25 Q8NI60,Q10713,Q99720 3 +Skeletal dysplasia 0.3667819506604456 0.5503412994031291 0.5820853024851638 1.0 1.0 45 P56589,Q9Y5Y5,Q9HC07,P16278,Q7RTS9,O75381,P50542,Q96HY6,P51648,P10619,O95831,Q14739,Q9NUQ7 13 +Mutism 0.3877676907560494 0.5501222205890737 0.5822355467944473 1.0 1.0 15 P53701,Q13510,P35637 3 +Abnormal bone structure 0.3494970269635995 0.5500218523886473 0.5823043853819561 1.0 1.0 177 P56589,Q15125,Q86XL3,O75718,P04062,Q9Y619,Q9HC21,Q15392,P06280,P51798,Q9Y4P3,P22626,O75844,Q13126,Q9BV10,O95831,Q14739,Q13510,Q99643,Q9Y487,Q9Y2B2,Q9NWM8,P07602,Q9HC07,Q7RTS9,P10644,O75845,O43292,Q9UBM7,Q9Y5Y5,O96028,Q14108,P38435,Q9NZJ7,P12235,P54802,Q96HY6,O43175,Q7LG56,O75381,Q9H490,Q9UG56,Q9NSD9 43 +Anti thyroid peroxidase antibody positivity 0.7557489123679231 0.547990337556381 0.5836985374844181 1.0 1.0 2 P00813 1 +Craniofacial dysostosis 0.5232771223158789 0.5475338242449722 0.5840120392061305 1.0 1.0 4 P10644,Q6NUK1 2 +Abnormality of the metacarpal bones 0.36850430109381 0.547029581172162 0.5843584095109873 1.0 1.0 39 P51798,O95202,Q8WVQ1,O96028,P16278,Q15233,O43909,Q7RTS9,P51812,Q6NUK1,P48651,O43924,P10644,Q14739,Q9UBM7,P16435,Q9NX62 17 +Polymicrogyria 0.3079350779763111 0.5469682996087466 0.5844005110276218 1.0 1.0 76 Q96N66,Q9Y5Y5,Q10713,P21281,Q96EK5,Q9Y487,P23786,Q9NZ01,O43175,O43505,O75381,Q15392,Q13509 13 +Ovarian cyst 0.3751741080036865 0.5433475851701206 0.5868905068618839 1.0 1.0 17 P31751,P10644,Q99643,P16435 4 +Broad phalanx of the toes 0.4808442322278854 0.5422493755182024 0.5876467251386865 1.0 1.0 5 Q7LGA3,Q6DKJ4 2 +Asymmetric septal hypertrophy 0.7535736482286898 0.5413880362867836 0.5882401515968825 1.0 1.0 2 P54802 1 +Abnormal patella morphology 0.3621136879079454 0.5410010375097453 0.5885068675943717 1.0 1.0 26 Q9Y4P3,Q15125,Q9Y619,O75419,O00192,P21964 6 +Abnormal blood phosphate concentration 0.4511599221697202 0.5386284376404106 0.5901432612840978 1.0 1.0 7 P51798 1 +Abnormality of central nervous system electrophysiology 0.3354080868102661 0.53798340659372 0.590588504396143 1.0 1.0 156 Q86SQ9,Q15125,P48449,P03886,Q96A33,Q9P0S2,P50897,Q9NZ01,Q9BQE5,Q9NQZ5,Q96N66,P07602,Q15067,O75503,P13073,O43292,P21964,Q9Y5Y5,O96028,Q14108,Q9UBX3,Q9NZJ7,Q9H2C2,O43175,O75381 25 +Hypoplastic female external genitalia 0.3906647082222578 0.5355945506390788 0.592238795742019 1.0 1.0 14 Q9Y619,O75419 2 +Macroglossia 0.3648648020697446 0.5326789117254902 0.5942558665168729 1.0 1.0 31 Q10713,P21281,Q7LGA3,P04066,Q96A33,P10253,Q99643 7 +Cranial nerve compression 0.403457130453565 0.5320150354720936 0.5947155819851073 1.0 1.0 11 P51798,P22626,Q99643 3 +External ophthalmoplegia 0.3562368392553908 0.530923919959431 0.5954715012416059 1.0 1.0 22 Q13509,P12235,P03886 3 +Abnormality of the phalanges of the hallux 0.7498446239900607 0.530143352646091 0.59601254309539 1.0 1.0 2 Q8WVQ1 1 +Complete atrioventricular canal defect 0.6209585999791887 0.5284716734384122 0.5971720026283438 1.0 1.0 3 Q9UHX1 1 +Muscle fibrillation 0.3787321031056542 0.5278538546846196 0.5976007748469705 1.0 1.0 16 Q13510,O95831 2 +Cerebellar atrophy 0.3246335837309307 0.5264484252054946 0.5985766773040502 1.0 1.0 141 Q9NQT5,Q9H6K4,Q13217,Q9NVI7,Q96CU9,Q9BT22,P51798,Q8NHS3,Q5T440,O75208,O00400,Q9NW15,Q6DKK2,Q9Y320,Q99757,P51649,Q9H9P8,Q9UHD1,Q10713,Q92643,P51572,O75503,O75787,P13073,O75845,O14773,Q9BVA1,O43292,Q8NI60,Q9Y5Y5,Q14108,Q9H270,Q6PJG6,P12235,P46977,Q5XKP0,Q7LG56,Q5BJH7,Q9H490,Q8IV08 40 +Hamstring contractures 0.7486016159105082 0.5264160640938782 0.5985991567333206 1.0 1.0 2 P33897 1 +Abnormal cellular phenotype 0.3554842125714522 0.5252021704841671 0.5994426562429618 1.0 1.0 190 O43676,P35637,P03886,Q9Y2R0,Q70HW3,P04062,Q9P0S2,Q9BUB7,P00846,Q96CU9,P51798,O75306,P00813,O75844,P23786,Q86Y39,Q9Y584,P49748,Q99757,Q9NPL8,Q9BV10,Q14739,Q13510,Q9UJW0,P07602,P28070,Q7KZN9,O75503,O43772,P13073,O14773,Q9Y6M9,P21964,Q14108,Q9UBX3,Q9NZJ7,P12235,O00192,P11166,Q7LG56,Q16134 41 +Limb girdle muscle weakness 0.3609161696133541 0.5248308892756879 0.5997007562708299 1.0 1.0 27 P07602,Q9NZJ7,O14979,P12235,Q13126 5 +Genu valgum 0.3638359824487867 0.5246363524006804 0.5998360107038407 1.0 1.0 31 Q9Y4P3,P51798,Q7RTS9,Q7LGA3,Q9Y619,Q9NR77,O75431,Q9NX62,Q13509 9 +Small intestinal dysmotility 0.7476693598508256 0.5236275483534544 0.6005376168929646 1.0 1.0 2 Q7LG56 1 +Abnormal placental membrane morphology 0.6188861461868671 0.521950250190934 0.6017049697939965 1.0 1.0 3 P21281 1 +Abnormality of thyroid physiology 0.3258341425004549 0.5204441615424298 0.6027540369075912 1.0 1.0 69 Q9Y4P3,Q13423,P00813,P21281,P03886,P04066,P12235,O00192,O95470,P10644,Q7LG56,O76024,P21964 13 +Arnold chiari type i malformation 0.4754027599776257 0.5200125941976113 0.6030547971555325 1.0 1.0 5 Q86SQ9 1 +Abnormality of adrenal morphology 0.3601046330098881 0.5186629454713146 0.6039958058387298 1.0 1.0 27 O75844,P10644,Q9ULK5,P16435,Q99643 5 +Increased circulating antibody level 0.3772018345682399 0.5179403934648932 0.6044998579810785 1.0 1.0 16 P28070,P04062,Q14108 3 +Temperature instability 0.4239559233726234 0.5152215382936324 0.6063982199129145 1.0 1.0 9 P07602,Q9NZJ7 2 +Abnormal tongue morphology 0.3300739901371777 0.5124448879710628 0.6083396821249845 1.0 1.0 67 P21281,Q96A33,Q9Y4P3,O75844,Q7LGA3,P04066,Q96J42,O75431,P07196,P98175,Q99643,Q10713,P42356,Q9UBM7,Q9Y5Y5,P16278,P10253,Q6NUK1,P21912,O43924 20 +Optic atrophy 0.3556752606555019 0.5116470040780057 0.6088980824825605 1.0 1.0 192 P56589,Q86SQ9,Q15125,P21281,P03886,Q9H061,Q9H6K4,Q9NVI7,P00846,Q15907,Q96CU9,P50897,P51798,O75306,P06280,Q86Y39,Q96J42,Q99757,Q9H9P8,O76024,P98175,Q9C0D9,P07602,Q15067,Q7KZN9,P51812,P10644,O43292,Q9UBM7,P21964,Q53FT3,Q9Y5Y5,O96028,Q9NZJ7,Q9H2C2,O00192,O43505,Q5XKP0,O75381,Q9H490 40 +Abnormal renal vascular morphology 0.6154802611128232 0.5112953922591973 0.6091442309868773 1.0 1.0 3 P21912,P42224 2 +Abnormal shape of the occiput 0.3606431719110073 0.5101490285654556 0.609947058770715 1.0 1.0 29 Q9Y5Y5,P21281,O43175,Q9BUB7,O75381,Q13509 6 +Abnormality of the elbow 0.3425446325114768 0.5089184039543134 0.610809419299474 1.0 1.0 61 Q03164,P23786,Q7RTS9,Q9H6K4,Q7LGA3,Q9Y619,O75419,P10644,Q13510,Q13509 10 +Abnormal circulating androgen level 0.4114130588308456 0.5084556800534042 0.6111338130110515 1.0 1.0 10 Q13423 1 +Confusion 0.3697691446420768 0.5073247293531384 0.6119269899029369 1.0 1.0 17 P05067,P36551,Q9Y619,O96008,P11166,P33897,Q9NZ08,Q9UJS0 8 +Limited knee extension 0.741454319453055 0.5051921893533732 0.6134238556947986 1.0 1.0 2 Q7RTS9 1 +Hypertriglyceridemia 0.3539462930471049 0.5046357392602416 0.6138147030425727 1.0 1.0 23 P50402,P28070,O95470,P31751,O75431,P38571,P22830,Q9UJS0 8 +Abnormal insulin level 0.3557708567455172 0.5009630657550972 0.6163971166805604 1.0 1.0 25 Q86SQ9,O75844,Q15555,P31751,P53985 5 +Flaring of rib cage 0.6115668729222381 0.4991509329407272 0.6176730584459778 1.0 1.0 3 Q7RTS9 1 +Tetany 0.4700726236244651 0.4984509099802356 0.6181662613145902 1.0 1.0 5 P21964 1 +X linked dominant inheritance 0.3542721905095102 0.4981566122410124 0.6183736609004149 1.0 1.0 24 Q15125,Q9NX14,P51812,P13473,P53701,P55795 6 +Chronic infection 0.4203617794343335 0.4968333104609629 0.6193066030695078 1.0 1.0 9 P51798 1 +Prominent antihelix 0.7377252952144118 0.4942628536365419 0.6211205554942785 1.0 1.0 2 P98175 1 +Abnormal urine carboxylic acid level 0.3510221499897742 0.4925651665340299 0.6223198658171087 1.0 1.0 22 Q9H6K4,Q9NVI7,Q5XKP0,Q9Y619 4 +Dysarthria 0.3410104822173033 0.4919694597603338 0.6227409335211325 1.0 1.0 170 P35637,O15118,Q9H6K4,P04062,O14653,P00846,Q96CU9,Q13509,O75306,Q9Y4P3,Q6DKK2,Q9NP80,P51648,P07196,O76024,P07602,Q10713,Q7KZN9,O75503,O75027,O14773,O43292,Q9Y5Y5,Q14108,Q9NZJ7,P12235,Q5XKP0,Q7LG56,Q8IV08 29 +Atrioventricular canal defect 0.4193126288592427 0.4914863662178867 0.6230824926383036 1.0 1.0 9 Q9UHX1,O75419 2 +Aplasia hypoplasia of the cerebellar vermis 0.3301945221135304 0.4879916952438191 0.6255557234844527 1.0 1.0 66 Q15125,Q10713,P21281,Q9Y487,P23786,Q96B26,Q9HC21,Q96J42,Q8NFH4,O43924,O43175,O43505,Q15907,Q9UBM7,P98175,Q9H490,Q13509 17 +Cerebral edema 0.4285706164604576 0.4869869020115144 0.6262676130305362 1.0 1.0 8 Q9P0S2 1 +Fat malabsorption 0.4073601985603422 0.4866680984730469 0.626493556127182 1.0 1.0 10 Q14739 1 +Aplasia hypoplasia of the scapulae 0.5062410100183647 0.4857284965099386 0.6271596766165262 1.0 1.0 4 Q7RTS9 1 +Postural instability 0.3663377587695089 0.4846130618492408 0.6279508464906374 1.0 1.0 17 O75503,P04062 2 +Abnormality of the odontoid process 0.428014957024246 0.4843028387913868 0.6281709615642921 1.0 1.0 8 Q7RTS9,P16278,O95831 3 +Pseudoepiphyses of hand bones 0.5053150657799986 0.4824336000929709 0.6294979570491537 1.0 1.0 4 O96028,P51812 2 +Pseudoepiphyses of the metacarpals 0.5053150657799986 0.4824336000929709 0.6294979570491537 1.0 1.0 4 O96028,P51812 2 +Weak cry 0.4172557953023293 0.481031877287898 0.6304938429591647 1.0 1.0 9 Q13510 1 +Abnormality of the lymphatic system 0.3233899307810705 0.4807182311295482 0.6307167720408615 1.0 1.0 144 P21281,O15118,P04062,Q96A33,P10619,P31751,Q9NZ08,Q15392,Q9BT22,P51798,P00813,P04066,Q96J42,Q14739,Q5HYI8,Q13510,P07602,Q10713,P28070,P10644,O75845,P21964,O96028,Q14108,Q9NZJ7,P10253,P54802,O00192,P11166,Q9ULK5 30 +Adrenocortical carcinoma 0.6051633046201299 0.479512017970669 0.6315744206289691 1.0 1.0 3 P10644 1 +Eyelid myoclonus 0.4059408630228003 0.4790729777299618 0.6318867127594165 1.0 1.0 10 Q13510,P00374 2 +Photoreceptor layer loss on macular oct 0.7311995027967738 0.4753818987275389 0.6345147940245768 1.0 1.0 2 P04439 1 +Anophthalmia 0.4050887981734525 0.4745224535837363 0.6351273901307248 1.0 1.0 10 P53701,Q96J42,O43505 3 +Large basal ganglia 0.3647885631063422 0.4744024418362556 0.6352129521062593 1.0 1.0 17 Q96N66,Q13509 2 +Gowers sign 0.3699910617475112 0.4715506476554281 0.6372475603918142 1.0 1.0 16 Q13510,Q9NP80 2 +Emg chronic denervation signs 0.3699310266459662 0.471166796756272 0.6375216275868882 1.0 1.0 16 Q13510,P07602,Q9NZJ7 3 +Inguinal hernia 0.3213235340723847 0.4687637739730403 0.639238496466535 1.0 1.0 69 Q9Y4P3,Q9NWM8,P21964,Q10713,Q9Y487,P16278,Q8NCH0,P51812,O00192,Q15555,O43175,Q9BUB7,Q9UHX1,Q9NSD9 14 +Chorioretinal dysplasia 0.4458715429100103 0.467029156898688 0.6404790177496196 1.0 1.0 6 P53701,O43505 2 +Abnormal vitreous humor morphology 0.4455984145075616 0.4658635455741128 0.6413131762846564 1.0 1.0 6 Q9NX14,P53701 2 +Abnormal anatomic location of the heart 0.3917689085428416 0.4656589279701039 0.6414596556799441 1.0 1.0 11 O75844,Q10713 2 +Aplasia hypoplasia of the phalanges of the hand 0.3513540524853021 0.4645471709126861 0.6422557718847228 1.0 1.0 52 P51798,Q9Y2B2,Q03164,P21281,P38435,O75844,Q7RTS9,P10644,Q14739,P16435,Q9UHX1 11 +Slender long bone 0.3686468810442246 0.4629662129795175 0.6433885854071817 1.0 1.0 16 Q9Y487,Q9Y619,O75419 3 +Abnormality of exocrine pancreas physiology 0.3569830746946213 0.4622313128196907 0.6439154504736844 1.0 1.0 18 P09601,Q15904,P40763,Q9UHX1,Q5HYI8,Q9UJW0 6 +Glaucoma 0.2861721426341888 0.4611838014188226 0.6446667423397614 1.0 1.0 94 P56589,Q86SQ9,Q15125,Q86XL3,P53701,O60566,Q9Y4P3,Q8NCH0,Q15555,O76024,Q9NX14,Q9UBM7,P21964,Q9Y5Y5,Q06136,P12235,O00192,O43505,Q7LG56,O75381 20 +Foot dorsiflexor weakness 0.3575069333049288 0.4608899727310985 0.6448775461816103 1.0 1.0 35 P05023,Q9BQT8,O15269,Q9NR77,Q7LG56,Q14739,Q99720 7 +Diffuse mesangial sclerosis 0.3502355525779171 0.4591968906907818 0.6460927831994592 1.0 1.0 19 P00813,Q9BW27,Q8NFH4,O95470,Q8N1F7 5 +Abnormal neuron morphology 0.3530005983799129 0.4581221539946467 0.6468646834305749 1.0 1.0 28 P22626,P35637,Q92804,Q13510,Q99720 5 +Hypohidrosis 0.4223837873973329 0.4572568107214301 0.6474864688618429 1.0 1.0 8 P06280 1 +Increased sulfur amino acid level in urine 0.4595644901637792 0.4566316985105633 0.6479357913110007 1.0 1.0 5 Q9H3L0 1 +Areflexia of lower limbs 0.3484510237668886 0.4551603473555548 0.6489938852468398 1.0 1.0 24 Q7LG56,Q9H6K4,Q15067,Q13217,P12235,Q9NR77,P07196,Q15041,Q16637 9 +Abnormal circulating bilirubin concentration 0.3525876378101368 0.4550061618875814 0.6491048058299227 1.0 1.0 28 Q9NSD9,P23786,P36551,P11166,Q9UGP8,O75845,P00390,Q14739,Q9UJS0 9 +Abnormal posterior segment imaging 0.4591163181566615 0.4548696015339847 0.6492030534548243 1.0 1.0 5 Q96S66,Q9C0D9,P04439 3 +Abnormal greater sciatic notch morphology 0.4587964220841762 0.4536129693610536 0.6501074171211301 1.0 1.0 5 Q7RTS9,Q96HY6 2 +Abnormality of iron homeostasis 0.4584758942457116 0.4523547919080934 0.6510134094905853 1.0 1.0 5 Q15477,Q02241,Q6PGP7,P28288 4 +Autoamputation 0.4319950202303202 0.45097459015589 0.6520078627044708 1.0 1.0 7 O15270,P48643,O15269,P39210,Q9H4A3,Q12756 6 +Renal tubular dysfunction 0.3566558963377538 0.4495072362142459 0.6530657892199443 1.0 1.0 40 O75306,O43676,P03886,Q86Y39,Q9NPL8,Q9Y6M9,Q16134,Q96CU9 8 +Abnormal cornea morphology 0.3223992197312046 0.448222849667105 0.6539923736478375 1.0 1.0 146 P56589,Q86SQ9,Q15125,Q96EK5,P04062,P10619,Q9NVI7,Q9NZ08,P53701,O60566,P06280,Q9Y4P3,Q9Y5Z9,O75844,Q8NCH0,Q7LGA3,P04066,Q15555,P51648,Q96J42,Q14739,Q13510,Q9Y2B2,Q9NWM8,O75845,Q9NX14,Q9UBM7,P21964,Q9Y5Y5,O96028,P16278,Q06136,P12235,O00192,O43505,O75381 36 +Decreased circulating level of specific antibody 0.4313103648674725 0.4479024236877687 0.6542236191385824 1.0 1.0 7 P00813,Q9BV10 2 +Spastic gait 0.3514778173696899 0.4466435591492327 0.6551324395103859 1.0 1.0 28 O75298,Q9BRK0,O00400,Q9Y619,Q9NVI7 5 +Tricuspid atresia 0.4950025646117975 0.4462238092007402 0.6554355860438927 1.0 1.0 4 P21964 1 +Multiple suture craniosynostosis 0.4950025646117975 0.4462238092007402 0.6554355860438927 1.0 1.0 4 P21964 1 +Hypertensive crisis 0.4950025646117975 0.4462238092007402 0.6554355860438927 1.0 1.0 4 P21964 1 +Secondary microcephaly 0.296764235881288 0.4440122688634734 0.6570337136655895 1.0 1.0 77 P00374,Q9HC07,O75208,Q86Y39,O75419,P55795,Q5XKP0,Q9BV10,Q96CU9,Q9UHX1,P50897 11 +Nuclear cataract 0.4395858106068473 0.4403760678643558 0.6596647552775803 1.0 1.0 6 Q99797,O76024 2 +Abnormal urine alpha ketoglutarate concentration 0.4188008859562182 0.440201862590395 0.6597909108439557 1.0 1.0 8 Q9P0S2 1 +Abnormal circulating methionine concentration 0.4378881557847905 0.4332411068316658 0.6648396181950129 1.0 1.0 6 Q9H3L0 1 +Abnormal venous morphology 0.3454354951203334 0.4330662237466306 0.6649666598802206 1.0 1.0 24 P04062,O00192,P98175,P21964,Q9Y487 5 +Shield chest 0.4373770840063841 0.431098615400402 0.6663966673605668 1.0 1.0 6 P04066 1 +Congenital contracture 0.3535564530100173 0.426335242379294 0.6698635811776517 1.0 1.0 42 O75844,Q8NCH0,P04062,O43175,Q15392 5 +Premature birth 0.3501376741169522 0.4210215947771752 0.6737393130336649 1.0 1.0 48 P56589,O43676,P51798,Q9Y5Y5,O75844,P04062,P50542,Q9BV10,Q9BUB7,Q9NX14,O75381,Q9UBM7 12 +Aplasia hypoplasia of the uterus 0.3563172862483617 0.4190901712258797 0.6751502335915638 1.0 1.0 17 P53701,Q16740 2 +Lethargy 0.2782271192243727 0.4181089931646604 0.6758674300202288 1.0 1.0 82 O43676,P03886,Q9Y619,Q9HC21,Q96CU9,O75306,P23786,Q86Y39,P49748,Q9NPL8,Q96EY8,O43772,Q9NX14,Q9Y6M9,Q9H3L0,O75251,P12235,P11166,Q96IX5,Q7LG56 20 +Petechiae 0.4046972516647773 0.4180710340791831 0.6758951822974615 1.0 1.0 9 P51798,P04062 2 +Cholecystitis 0.4045145896123389 0.4171671416072811 0.6765561574009946 1.0 1.0 9 P07602 1 +Corneal neovascularization 0.4490136321797783 0.4156488592671982 0.6776669684385792 1.0 1.0 5 P21964 1 +Low set posteriorly rotated ears 0.3034649714413107 0.4155665072366074 0.6777272391871862 1.0 1.0 74 P56589,Q4J6C6,Q9Y4P3,Q10713,Q9Y5Y5,O96028,Q8NCH0,P04062,Q96J42,O43924,P16435,O75381,P98175,Q9UBM7,O60566,Q15392 16 +Scrotal hypoplasia 0.365869547207721 0.4135779106138872 0.6791832532786612 1.0 1.0 15 P46977,Q15555,Q9BV10,P16435,Q9UBM7 5 +Abnormal upper motor neuron morphology 0.3931939090495933 0.4117592912321688 0.6805158620159117 1.0 1.0 10 Q99720 1 +Upper limb asymmetry 0.7082038533250457 0.4114884434376302 0.6807144135253917 1.0 1.0 2 Q15555 1 +Abnormality of the inner ear 0.4026936328470365 0.4081761260172523 0.6831443742332328 1.0 1.0 9 Q9Y619 1 +Chylothorax 0.4469673405909762 0.4078262643411561 0.6834012298233181 1.0 1.0 5 P49815,P22681,Q06124,P52732 4 +Proximal upper limb amyotrophy 0.4317626671751739 0.4077331899342641 0.6834695678069629 1.0 1.0 6 O14979 1 +Abnormality of the musculature of the upper arm 0.4317626671751739 0.4077331899342641 0.6834695678069629 1.0 1.0 6 O14979 1 +Abnormality of adrenal physiology 0.3498613282141835 0.4074651087919504 0.6836664154051517 1.0 1.0 33 P56589,Q13423,Q9Y5Y5,P50542,O95470,P10644,P33897,O75381,P16435 9 +Abnormal circulating amino acid concentration 0.3416218984029393 0.4063078933198002 0.6845163864055899 1.0 1.0 55 Q99797,Q96EY8,O75208,P03886,Q9Y619,Q9NP80,Q9P0S2,O43175,Q5XKP0,P22695,Q9BUB7,Q7LG56,P00846 13 +Cns hypomyelination 0.3500855734565528 0.4054904416551423 0.6851170429707731 1.0 1.0 45 O00400,Q5BJH7,O43175,Q99720 4 +Abnormal pulmonary thoracic imaging finding 0.348414471878948 0.4048426097816627 0.6855932058048546 1.0 1.0 18 Q9NZ08,Q13510,P04062,P21964 4 +Large for gestational age 0.4019661648466921 0.4045944645081375 0.6857756281274974 1.0 1.0 9 P31751 1 +Thin skin 0.3401498878457372 0.4039529999155087 0.686247281339688 1.0 1.0 23 O75844,Q13126 2 +Abnormal atrioventricular valve morphology 0.3502279143963306 0.4034041192003235 0.6866509569410548 1.0 1.0 35 Q9Y4P3,O75844,P04062,P51812,O00192,O75431,P53701,P55795,P21964 9 +Amblyopia 0.3591745929928789 0.4031063176033761 0.6868700132338241 1.0 1.0 16 Q9UHX1,Q13509 2 +Inverted nipples 0.4016472278238203 0.4030260551554015 0.6869290570217434 1.0 1.0 9 Q15067,Q9BV10 2 +Synostosis involving digits 0.4820519180147102 0.4021022123529065 0.6876088046583586 1.0 1.0 4 P48651 1 +Hyperconvex fingernails 0.4300338164724619 0.400603200967037 0.6887122885906982 1.0 1.0 6 O95202,O96028,P51812 3 +Focal white matter lesions 0.4096354131480514 0.397162429082002 0.6912476857976246 1.0 1.0 8 Q7LG56,P12235 2 +Abnormality of hair texture 0.3416710962277581 0.3952831104030213 0.6926339625918012 1.0 1.0 54 P51798,Q9Y2B2,Q15125,O75844,Q96A33,P54802,O43175,Q9NVI7,P55795,Q9Y487 10 +Serositis 0.3407853655626509 0.3940758513262574 0.6935250392795322 1.0 1.0 19 Q9NZ08,Q9BW27,Q8NFH4,Q8N1F7 4 +Aplasia hypoplasia of the cerebellum 0.3068736882243807 0.3932189942774873 0.6941577419362834 1.0 1.0 129 Q15125,P21281,Q9NVI7,Q15907,Q13509,P23786,Q96J42,Q9BV10,Q9H9P8,P55795,P98175,P00374,Q9Y487,Q96B26,Q10713,P51812,O43292,O96028,Q8NFH4,O43175,Q5XKP0,O43505,Q9ULK5,O43924,Q9H490 25 +Abnormality of the dorsal column of the spinal cord 0.4785447761193951 0.3904313108824886 0.6962176386132284 1.0 1.0 4 Q6PI48,P33897,P54886 3 +Abnormal acetabulum morphology 0.3354161817265519 0.3902699693886187 0.6963369271257656 1.0 1.0 21 Q8WVQ1,P16278,O43909,Q7RTS9,O75718,Q9Y584,Q969X5,Q9NUQ7 8 +Abnormality of the lymph nodes 0.3486399040279649 0.3883042108562629 0.6977909214620925 1.0 1.0 36 P51798,P00813,P28070,Q01844,P10644,Q9NZ08,Q5HYI8,Q13510 8 +Gastroparesis 0.3984095856620918 0.387170174205158 0.6986302291244879 1.0 1.0 9 Q7LG56,P12235 2 +Abnormality of the common coagulation pathway 0.3737535268958919 0.3851184669416834 0.7001496466248494 1.0 1.0 12 Q9BV10,P38435 2 +Lower limb amyotrophy 0.3453220927381547 0.3843917289974646 0.7006881298454415 1.0 1.0 18 P07196,O00400,Q9NR77,Q9NVI7 4 +Fatigable weakness of bulbar muscles 0.3654352435750209 0.3833909641149393 0.7014299020528472 1.0 1.0 14 Q92804,P35637,Q15165 3 +Osteolysis 0.3420146483438797 0.3833643981889553 0.7014495967386021 1.0 1.0 27 Q9Y2B2,P22626,Q14108,O75844,P04062,O60566 6 +Abnormality of the skull base 0.3364403400824999 0.3821994866152476 0.7023134026051876 1.0 1.0 57 Q15125,Q10713,P21281,P23786,P49748,Q96J42,Q9NPL8,O43175,O43505,Q14739,Q9H490,Q9UHX1,Q9Y487 13 +Knee clonus 0.6970167806090539 0.381993681883573 0.7024660510545113 1.0 1.0 2 O75298 1 +Abnormal vitamin b12 level 0.4162034324494342 0.381313564684038 0.7029705894900917 1.0 1.0 7 Q96EY8,Q9H3L0 2 +Bloody diarrhea 0.4757462686567097 0.3812075822064146 0.7030492233669237 1.0 1.0 4 Q02241,Q6PGP7,Q15477 3 +Decreased circulating igg subclass level 0.6957737725294976 0.3787841507517099 0.7048481577874621 1.0 1.0 2 P00813 1 +Cerebellar vermis atrophy 0.3724899879037762 0.3780646462639455 0.705382570750883 1.0 1.0 12 Q10713 1 +Subependymal cysts 0.5690094909908026 0.3746401648255721 0.7079280977903306 1.0 1.0 3 Q99757 1 +Abnormal nerve conduction velocity 0.3471739976696791 0.3732519788740313 0.7089609132921293 1.0 1.0 42 P07602,Q9NZJ7,O15269,Q9Y619,Q9NR77,O95831,Q7LG56,Q99720 8 +Abnormal urine ph 0.3467704092700062 0.3716197225760071 0.7101760026380906 1.0 1.0 43 Q96EY8,P03886,P23786,Q9BQT8,P12235,Q9P0S2,P49748,O43772,Q9H9P8,P00846,Q16134,Q9H3L0 12 +Abnormal circulating albumin concentration 0.345175938131128 0.3714277779612859 0.710318939150562 1.0 1.0 33 Q9BW27,Q8NFH4,O95470,Q5XKP0,Q9BV10,Q9NSD9 6 +Esodeviation 0.3469938824641931 0.3706900015623793 0.7108684382165773 1.0 1.0 39 P04062,O43175,Q9NVI7,Q7LG56,O43924,Q9UHX1,Q13509 7 +Spina bifida 0.345562474798 0.3704066676192949 0.7110795065261666 1.0 1.0 34 Q9Y4P3,P21964,Q10713,P21281,O00192,O43175,O75845,Q9ULK5,Q8TAA9,Q9UHX1 10 +Acute pancreatitis 0.4723258706467587 0.370043963930183 0.7113497332887389 1.0 1.0 4 P02545,Q96MF7,O15120 3 +Absent facial hair 0.3948753651945967 0.3700025044475656 0.7113806243443082 1.0 1.0 9 O75844 1 +Adult onset 0.3076813600779003 0.369543568147022 0.7117226049449727 1.0 1.0 71 Q9NQZ5,P07602,P38435,O15118,O14979,P04062,Q9Y4G8,P12235,P31751,Q8IV08,O76024,Q99643 12 +Abnormal cortical bone morphology 0.3480664644806869 0.3661718545835772 0.7142368427067765 1.0 1.0 17 P51798,Q86XL3 2 +Diplopia 0.3425297627794652 0.3660552526813018 0.7143238467566735 1.0 1.0 18 Q9NW15,P04062,Q13472,P11166,O14773,O43464,Q6Y7W6 7 +Esophageal varix 0.4702478825319229 0.3633219040265454 0.7163644326492236 1.0 1.0 4 P04062 1 +Protrusio acetabuli 0.5631050855102051 0.3585789697890655 0.7199100816026194 1.0 1.0 3 O75718 1 +Hypogonadism 0.2705013356450094 0.3585318415586678 0.7199453433894232 1.0 1.0 83 Q86SQ9,P48449,P03886,O75844,Q9BT22,O95470,O43175,P10644,Q7LG56,O76024,Q16740 11 +Falls 0.3922699197173109 0.3574443011273335 0.7207592167809889 1.0 1.0 9 P21912,Q9BQT8 2 +Coarse hair 0.3412110934891577 0.3574407670015918 0.7207618621009297 1.0 1.0 18 P54802,Q9Y487,Q96A33,P51812 4 +Extra axial cerebrospinal fluid accumulation 0.6864512119328849 0.3551570739028505 0.7224719211644162 1.0 1.0 2 Q03252 1 +Limited hip movement 0.3683025035305282 0.354842184935478 0.7227078231415127 1.0 1.0 12 O75844 1 +Beaking of vertebral bodies 0.4003126049356746 0.3543382736509696 0.7230853877689429 1.0 1.0 8 Q7RTS9,P04066 2 +Cardiorespiratory arrest 0.5613812229108002 0.3539506821962773 0.7233758435416582 1.0 1.0 3 O43772 1 +Microglossia 0.4664210149043114 0.3510639552922611 0.7255403685453081 1.0 1.0 4 P48651,Q9UBM7 2 +Cervical spinal canal stenosis 0.6845866998135515 0.3505272984692569 0.7259430068604076 1.0 1.0 2 O43909 1 +Hypoplasia of teeth 0.3400529763217131 0.3498996249684161 0.7264140284952081 1.0 1.0 18 O75844 1 +Exodeviation 0.3310652790248057 0.3492333534727205 0.7269141282082352 1.0 1.0 22 Q9UHX1,Q13509 2 +Focal onset seizure 0.2704300356014132 0.3464711524132434 0.7289886602790308 1.0 1.0 84 Q96N66,P07602,P21281,Q9UBX3,P03886,Q9NZJ7,Q9NP80,O75503,Q9NZ01,O43175,Q13509 11 +Absent hair 0.3697243827926073 0.3444990051710578 0.7304710440596389 1.0 1.0 11 O75844 1 +Autoamputation of digits 0.4639303482586984 0.3431722713216684 0.7314688637192504 1.0 1.0 4 P48643,Q9H4A3,P39210 3 +Acral ulceration 0.4639303482586984 0.3431722713216684 0.7314688637192504 1.0 1.0 4 P48643,Q9H4A3,P39210 3 +Abnormality of the periungual region 0.4639303482586982 0.3431722713216678 0.7314688637192508 1.0 1.0 4 P40763,P49815,Q9H4A3 3 +Hypoplasia of the radius 0.3892441371043005 0.3429684548803287 0.7316221917779193 1.0 1.0 9 P10644,Q9BV10 2 +Megalocornea 0.3693749237975647 0.3426284974668811 0.7318779604984404 1.0 1.0 11 O96028,Q96EK5 2 +Renal agenesis 0.3386087604176893 0.3393184796733522 0.7343698228145226 1.0 1.0 51 O75306,Q86XL3,Q7LGA3,O43175,P10644,Q8TAA9,O43924,Q15392,Q9UHX1 9 +Cerebral hypomyelination 0.3383621622031071 0.3389319814346709 0.7346609711821896 1.0 1.0 18 Q9Y2B2,Q9H270,P51572,O43175,O75340 5 +Short nose 0.2760257346688061 0.3386865777103795 0.7348458531278361 1.0 1.0 92 Q9Y4P3,P42892,Q03164,P38435,O75844,Q8NCH0,P04062,Q02252,Q9H490,P10644,Q9NVI7,P16435,O75845,O60566,Q15392,Q9UHX1,Q9Y487 17 +Chronic diarrhea 0.3381695634268045 0.3376859032164321 0.7355998989885193 1.0 1.0 18 Q13510,Q96A33,Q9BT22 3 +Epiphyseal dysplasia 0.396612615880338 0.3376339338148825 0.7356390668539277 1.0 1.0 8 Q7RTS9,Q9HC07,O43909 3 +Primitive reflex 0.4059605997753164 0.3376061932728102 0.7356599743958112 1.0 1.0 7 Q13509 1 +Cerebellar hypoplasia 0.2921492940724794 0.3361212592543144 0.7367794275603705 1.0 1.0 114 Q15125,P21281,Q9NVI7,Q15907,Q13509,P23786,Q96J42,Q9BV10,P55795,P98175,P00374,Q9Y487,Q96B26,Q10713,O43292,Q8NFH4,O43175,Q5XKP0,O43505,O43924,Q9H490 21 +Anterior uveitis 0.6786824114356822 0.3360811589096857 0.7368096659278514 1.0 1.0 2 P14174 1 +Omphalocele 0.3647916590243918 0.3355636128158672 0.7371999671835254 1.0 1.0 12 Q14739 1 +Hyporeflexia 0.2989325730545529 0.331365421064638 0.7403684808397866 1.0 1.0 124 Q86SQ9,P35637,P21281,P03886,P04062,P35610,P00846,P05023,O15269,O95831,Q99720,P07602,Q10713,O14979,Q15067,Q9NZJ7,Q9H2C2,P12235,P54802,Q9NR77,O43505,Q7LG56 22 +Broad ribs 0.4262224889329589 0.3310793065995853 0.7405845819660728 1.0 1.0 5 Q7RTS9,P16278 2 +Central nervous system cyst 0.3297279734438066 0.3308613630976458 0.7407492075699249 1.0 1.0 58 Q15125,O96028,P21281,P23786,Q96J42,Q99757,O43175,O43505,P00846,Q9UHX1,Q9Y487 11 +Confetti like hypopigmented macules 0.6761963952765773 0.3300974438003503 0.741326334635223 1.0 1.0 2 Q15233 1 +Shagreen patch 0.6761963952765631 0.3300974438003171 0.7413263346352481 1.0 1.0 2 Q6NUK1 1 +Easy fatigability 0.329474651558009 0.3281074944717755 0.7428303876258231 1.0 1.0 23 Q9NWM8,P10644,P12235 3 +Abnormality of the musculature of the thigh 0.3943961005623454 0.3277111360062803 0.7431300826584479 1.0 1.0 8 P07196,O14979 2 +Joint dislocation 0.2744626101474161 0.3273691666214459 0.7433886842401367 1.0 1.0 91 P51798,P21964,Q9Y4P3,Q15125,O96028,Q9Y2B2,O75844,Q8NCH0,Q9Y619,Q96A33,O75419,P10644,P51571,Q9UBM7,Q9UHX1,Q9Y487 16 +Abnormal serum iron concentration 0.4583333333333272 0.3256927561576661 0.7446568254159815 1.0 1.0 4 Q02241,Q6PGP7,Q15477 3 +Abnormality of the phalanges of the toes 0.3465915788923825 0.3255717170620734 0.7447484137648226 1.0 1.0 16 Q9Y2B2,O75844,Q7LGA3,P21281 4 +External ear malformation 0.3362368116214292 0.3252188055563951 0.7450154768589425 1.0 1.0 18 P56589,Q9Y5Y5,Q8NCH0,Q15555,O75381 5 +Abnormal femoral head morphology 0.3260385919333435 0.3247006799012542 0.7454076200319957 1.0 1.0 21 P16278,Q7RTS9,Q7LGA3,P50542,O75431,O95831,Q9NUQ7 7 +Spastic tetraplegia 0.3412314306635255 0.3239472005634889 0.7459780082499328 1.0 1.0 40 Q5T440,Q86XL3,P16278,Q13057,P04066,Q9Y320,P42356,O43175,Q9UEY8,Q5BJH7,Q13509 11 +Extrapyramidal dyskinesia 0.5496663708009097 0.3232512888520037 0.746504941138719 1.0 1.0 3 P35610 1 +Bull s eye maculopathy 0.6721566190180214 0.3205006318951134 0.7485888514254933 1.0 1.0 2 Q8NHS3 1 +Abnormality of skeletal maturation 0.2724298417277365 0.3202381351776449 0.7487878164296791 1.0 1.0 89 Q03164,P48449,O96028,Q14108,P04062,Q9Y619,O75419,P13073,P10644,O95831,Q7LG56,P16435,Q15800,Q9NSD9 14 +Abnormal renal pelvis morphology 0.333473364806854 0.3190530947946838 0.7496862511654081 1.0 1.0 54 P56589,Q9Y2B2,Q9Y5Y5,Q15125,P21281,P23786,Q8NCH0,O43505,O76024,P16435,O75381,Q9UBM7,P98175 13 +Metaphyseal widening 0.3235473548139419 0.3185376359214714 0.7500771508300219 1.0 1.0 20 O95831 1 +Abnormality of acid base homeostasis 0.3312581264233262 0.3147215373078376 0.7529730902310678 1.0 1.0 175 O43676,Q99797,P03886,Q70HW3,Q9Y619,Q9P0S2,P35610,O14949,Q9NVI7,Q9BUB7,P00846,Q96CU9,O75306,Q9BWD1,O75208,P23786,Q86Y39,Q9NP80,Q9Y584,P49748,Q99757,Q9NPL8,O95831,Q9H9P8,Q96EY8,Q10713,Q7KZN9,P13073,Q9Y6M9,P53985,Q9H3L0,Q8NI60,Q9UBX3,P12235,Q5XKP0,P22695,Q7LG56,Q16134 38 +Narrow mouth 0.3025598706116123 0.3102819056083046 0.756346589842102 1.0 1.0 71 P21964,O75844,Q8NCH0,P04062,Q7LGA3,Q9Y619,O75419,O00192,Q15555,Q9NVI7,P16435,Q15392,Q9NX62,Q9Y487 14 +Pigmentary retinopathy 0.3379761736147132 0.3100581003856877 0.7565167741581535 1.0 1.0 47 O75306,O75251,Q7LG56,P03886,Q15067,Q7KZN9,P50542,Q9NX14,P21912,Q15555,P53701,P00846,Q96CU9,O76024,Q9UG56 15 +Abnormal circulating follicle stimulating hormone concentration 0.4201669075037046 0.3096291765797913 0.756842966233092 1.0 1.0 5 P16435 1 +Abnormal umbilicus morphology 0.3324273186701951 0.3094205205516203 0.7570016626306697 1.0 1.0 54 Q9NWM8,O75844,Q8NCH0,O43175,Q9BUB7,Q14739,P21964,Q9Y487 8 +Truncus arteriosus 0.3820039751175134 0.3088287530065574 0.7574517958180964 1.0 1.0 9 P21964,Q9UHX1 2 +Micropenis 0.324443233029245 0.308254982993496 0.7578883175822797 1.0 1.0 60 Q86SQ9,P42892,P48449,Q10713,Q9NX14,Q9Y619,O75419,P46977,O95470,P16435,Q9NVI7,Q9BV10,P53701,O43505,Q9UBM7,O60566 16 +Delayed myelination 0.2769055891713537 0.3079256070347002 0.7581389402917051 1.0 1.0 80 Q53FT3,O15047,Q7LGA3,Q02252,Q9Y584,Q99757,O43175,Q9BV10,O95831,Q15907,Q96CU9,Q9H490,P00374 13 +Truncal titubation 0.6665630826600251 0.3074751367161049 0.7584817450508161 1.0 1.0 2 Q6PJG6 1 +Cavum septum pellucidum 0.3810348381650291 0.3043147495277738 0.7608881092084454 1.0 1.0 9 Q9BVA1,O96028,Q9BV10 3 +Abnormal cerebral artery morphology 0.3517393539634085 0.3042596560523436 0.7609300787683884 1.0 1.0 14 P10644,P10253,P38435 3 +Abnormal subarachnoid space morphology 0.3348727278291185 0.3041775681811531 0.760992613645727 1.0 1.0 31 Q9P0S2,O95831,P03886 3 +Urinary bladder sphincter dysfunction 0.3589554153612176 0.3039288194868039 0.7611821209558931 1.0 1.0 12 Q9BRK0,P22626,Q9NR77,O75298 4 +Difficulty standing 0.4055756686075382 0.3033873776769282 0.7615946638208939 1.0 1.0 6 O43292 1 +Goiter 0.3883115475121796 0.3008107814319426 0.7635587865789284 1.0 1.0 8 Q7LG56,Q99643,P12235 3 +Rickets 0.4169574165992403 0.2984495317711823 0.7653600896235666 1.0 1.0 5 O43175 1 +Myopathy 0.2804941529002402 0.2959534467714523 0.7672656336621735 1.0 1.0 102 O75306,O43676,Q9NWM8,Q9Y4P3,P22626,P03886,P23786,O14979,Q8NCH0,Q86Y39,P12235,Q13126,P10644,Q7LG56,P00846,O76024 16 +Cutaneous abscess 0.5381198002733156 0.2943267467951801 0.7685082363435765 1.0 1.0 3 Q13546 1 +Patellar dislocation 0.3193012019855755 0.2896858740532738 0.7720565640478709 1.0 1.0 20 Q9Y4P3,O00192,Q15125,P21964 4 +Abnormality of the septum pellucidum 0.3366903674445055 0.2888376666444508 0.7727056061752124 1.0 1.0 39 Q96N66,Q9NZ01,O43175,O43505,Q9BV10,P53701,Q15392 7 +Abnormality of the optic nerve 0.3710506910650176 0.2882106259372373 0.7731855154154337 1.0 1.0 252 O43676,Q9Y287,Q15125,Q86SQ9,P21281,P03886,Q9H061,Q9H6K4,P04062,Q9NVI7,Q9NZ08,P00846,Q15907,Q96CU9,Q13509,P51798,P50897,O75306,P06280,Q86Y39,Q7LGA3,Q96J42,Q99757,Q9NPL8,O95831,Q9H9P8,P07196,O76024,P98175,Q9C0D9,P07602,Q10713,Q15067,Q7KZN9,P51812,P10644,Q9Y6M9,O43292,Q9UHX1,P21964,Q53FT3,Q9Y5Y5,O96028,P38435,Q9NZJ7,Q9H2C2,O43505,Q5XKP0,O75381,Q9H490,Q9UG56 51 +Spondyloepiphyseal dysplasia 0.6578620261031782 0.2878301145972161 0.7734767842744534 1.0 1.0 2 Q9NSE4 1 +Absent septum pellucidum 0.3339802749776986 0.2869340688918591 0.7741628036046468 1.0 1.0 33 Q96N66,Q9NZ01,O43175,O43505,P53701,Q15392 6 +Elevated circulating follicle stimulating hormone level 0.4436358495103498 0.2815514750609056 0.7782874526807164 1.0 1.0 4 P16435,P51809 2 +Epileptic spasm 0.3108719446877437 0.2787093162103958 0.7804679124108265 1.0 1.0 66 Q96N66,Q9UBX3,P03886,O43175,P00846,Q13510 6 +Abnormal circulating dicarboxylic acid concentration 0.3353734891101395 0.2778271920864208 0.7811450163451639 1.0 1.0 43 Q96EY8,Q9NSD9,P23786,P22695,O75845,Q9H9P8,Q14739,Q16134,Q9H3L0 9 +Abnormality of the carpal bones 0.3337601892870421 0.2771093205980646 0.7816961651733871 1.0 1.0 17 Q7RTS9,Q15125 2 +Heparan sulfate excretion in urine 0.5305632523187158 0.2761452064381543 0.7824365403112996 1.0 1.0 3 P54802 1 +Developmental cataract 0.3276229595045456 0.275173689591478 0.7831827996321912 1.0 1.0 55 Q99797,P48449,P03886,O00400,O43175,Q16134,O76024,Q15800 8 +Corticospinal tract hypoplasia 0.6516469857054159 0.2742663906454456 0.7838799109165557 1.0 1.0 2 Q13045 1 +Atelectasis 0.3532411951105272 0.273491706610256 0.7844752665958541 1.0 1.0 12 Q13510,P21964 2 +Atonic seizure 0.3229707832466983 0.273320655655706 0.7846067386966982 1.0 1.0 24 O43292,O14653,O43175,Q01105,Q13510 5 +Agenesis of incisor 0.6510254816656398 0.2729317678412869 0.7849056660519858 1.0 1.0 2 P41227 1 +Delayed ability to stand 0.5286456493685663 0.2716279518646602 0.7859081047729017 1.0 1.0 3 P10253 1 +Nonimmune hydrops fetalis 0.3264208699516734 0.2711171074236224 0.7863009643491012 1.0 1.0 27 Q14739,P10619 2 +Retinal degeneration 0.3206470960541164 0.2709105109776451 0.786459860644213 1.0 1.0 60 Q86SQ9,Q10713,Q9H2C2,P04062,O75503,P51648,O14773,Q13510,P50897 9 +Abnormal paranasal sinus morphology 0.3274669106971511 0.269559887677317 0.7874988632657671 1.0 1.0 18 Q03518,P28070,P10644,P04066 4 +Heart block 0.3207228879690327 0.267601003207928 0.7890064586701591 1.0 1.0 23 P23786,P49748,O43772,Q7LG56,Q9H490,P06280 6 +Capillary malformation 0.3485581774709251 0.2660874014344003 0.7901718975483818 1.0 1.0 13 Q9UHX1 1 +Abnormality of the auditory canal 0.317350836084695 0.265534640128762 0.7905976283217602 1.0 1.0 21 O96028,P16435,Q9Y619,O75419 4 +Radioulnar dislocation 0.5256420584032198 0.2646322115977839 0.7912928032446396 1.0 1.0 3 P16435 1 +Abnormality of the radioulnar joints 0.5256420584032198 0.2646322115977839 0.7912928032446396 1.0 1.0 3 P16435 1 +Abnormality of globe size 0.3251329069870074 0.2626483791134505 0.7928216076019656 1.0 1.0 56 P21964,Q15125,Q9NX14,Q02252,O00192,P11166,Q96J42,Q15555,O43175,O75431,Q12797,O43505,P53701,O43924,O60566,Q9UHX1 16 +Abnormal cry 0.3540406201946198 0.2623964968062683 0.7930157732349561 1.0 1.0 11 Q13510 1 +Urinary incontinence 0.3335038822104058 0.2620693586646823 0.7932679696281437 1.0 1.0 42 P07602,P35637,O75298,Q9NZJ7,P51812,P07196,Q9ULK5,Q8TAA9,Q99720 9 +Hepatic encephalopathy 0.4368229315821347 0.2620005660848211 0.793321005757893 1.0 1.0 4 Q6NUQ1,Q9UJS0 2 +Delayed puberty 0.3309006195135308 0.2589339760000727 0.7956861828633643 1.0 1.0 49 Q14108,O75844,P04062,P16435,O76024,Q15800,P06280 7 +Abnormal lumbar spine morphology 0.3626545237881154 0.2587007003081166 0.7958661791857262 1.0 1.0 10 P04062,O75845,P51812 3 +Overriding aorta 0.3708017487297173 0.2575142641677048 0.7967818052998783 1.0 1.0 9 Q9Y4P3,P53701 2 +Impotence 0.3932794026135531 0.2574200486318083 0.7968545276721455 1.0 1.0 6 P07686,P20700,Q06787,P33897,Q969G3 5 +Erectile dysfunction 0.3932794026135531 0.2574200486318083 0.7968545276721455 1.0 1.0 6 P07686,P20700,Q06787,P33897,Q969G3 5 +Pulmonary artery stenosis 0.3350141261043647 0.2566502271041931 0.797448797694351 1.0 1.0 16 P51798,Q9Y4P3 2 +Generalized muscle weakness 0.3282066120585281 0.2555855969049075 0.7982708410994583 1.0 1.0 31 P35637,Q92804,P10253,P12235,O95831 5 +Abnormal labia morphology 0.3251840937492004 0.2553347430459915 0.7984645679596545 1.0 1.0 18 Q9Y619,O75419 2 +Vascular neoplasm 0.3296324531188456 0.2548284553971373 0.7988555964059456 1.0 1.0 33 O96028,P21281,Q7LGA3,P10619,Q9UHX1,P16435,Q99643 7 +Hypoplasia of the brainstem 0.327164848795566 0.2544477289489621 0.7991496815985644 1.0 1.0 30 Q10713,Q96EK5,Q13509 3 +Choanal stenosis 0.4326921067195688 0.250440260766158 0.8022468977786841 1.0 1.0 4 P16435 1 +Tremor by anatomical site 0.3207195035956204 0.2486113978380723 0.80366139107132 1.0 1.0 25 Q9NR77,P35637,Q99720 3 +Abnormal waist to hip ratio 0.3839558634174335 0.248360831304009 0.8038552363795317 1.0 1.0 7 P31751 1 +Short palm 0.3161022227369529 0.2465538831818907 0.8052534986770485 1.0 1.0 22 Q9Y2B2,Q9UHX1,P10644,Q9Y619 4 +Short sternum 0.5171539203755846 0.2453961926401969 0.8061496767384915 1.0 1.0 3 P98175 1 +Functional motor deficit 0.3101725568281043 0.2430941549837357 0.8079324590772363 1.0 1.0 150 Q86SQ9,P35637,P03886,Q9Y2R0,P04062,O14653,P53701,P00846,Q15907,P23786,P07196,Q13510,Q9C0D9,Q99720,Q9NWM8,P07602,Q7RTS9,Q15067,P10644,O14773,O43292,Q8NI60,Q9NZJ7,Q9H2D1,Q9H2C2,P12235,Q9NR77,Q7LG56,Q9NSD9 29 +Emotional lability 0.3269418841324396 0.2430047076525203 0.8080017505678458 1.0 1.0 52 O75306,P07602,P35637,Q9NZJ7,Q92804,Q7KZN9,P10644,Q96CU9,Q13509 9 +Acanthocytosis 0.3892364132168772 0.2427829169887413 0.8081735699677215 1.0 1.0 6 O75845,Q9Y6B6 2 +Abnormality of upper limb epiphysis morphology 0.3368189880862825 0.2426714650997362 0.8082599143211928 1.0 1.0 15 Q5JRA6,O96028,Q7RTS9,P51812,P10644,P16435,O15228 7 +Cone shaped epiphysis 0.3440326397114725 0.2418665533497928 0.8088835673246779 1.0 1.0 13 Q7RTS9,O95831 2 +Abnormal glomerular mesangium morphology 0.3119891908700875 0.2409586290757001 0.8095871810865922 1.0 1.0 20 P00813,Q9BW27,Q8NFH4,O95470,Q8N1F7 5 +Facial hemangioma 0.3996102268663941 0.2404434035095327 0.8099865337699461 1.0 1.0 5 P16435 1 +Tricuspid valve prolapse 0.514769326546157 0.2401360789742607 0.8102247653845744 1.0 1.0 3 P53701 1 +Urticaria 0.3465300324941314 0.2384797744303938 0.8115090005511809 1.0 1.0 12 P51648 1 +Congenital hepatic fibrosis 0.3878012690574139 0.2376465904872829 0.8121552115141273 1.0 1.0 6 Q10713 1 +Bulbar palsy 0.358141546326348 0.2372918837236056 0.812430358171059 1.0 1.0 10 P35637,P53007,P33897,P31483,P43243 5 +Prominent nasal bridge 0.3301634826641265 0.2369049768481809 0.8127305089187469 1.0 1.0 44 Q9Y2B2,P42892,Q15125,Q10713,Q96EK5,P13073,Q9BV10,O43924,P21964 9 +Aspiration 0.356302601251182 0.2286712521440195 0.819124440251807 1.0 1.0 10 P42356,P17900,P43243,P06865 4 +Uncombable hair 0.6283405842138071 0.2269803605868627 0.8204390136143136 1.0 1.0 2 Q15477 1 +Conical tooth 0.3846123493291 0.2263474647977473 0.8209311845789873 1.0 1.0 6 Q9Y487 1 +Hypoplastic facial bones 0.3252800535275534 0.2262295946699141 0.8210228539952578 1.0 1.0 17 Q7RTS9,Q9ULK5,P16435 3 +Neoplasm of the larynx 0.4235074626865583 0.2255575663001358 0.8215455474853264 1.0 1.0 4 O96017,P43246,P52701 3 +Aplasia hypoplasia of the epiglottis 0.6274083281541429 0.225208593076429 0.8218170048450433 1.0 1.0 2 P38919 1 +Aplasia hypoplasia involving the femoral head and neck 0.35513456557121 0.2232275610384338 0.8233584024788074 1.0 1.0 10 Q96HY6,O75431,P50542,O95831 4 +Delayed closure of the anterior fontanelle 0.3435414698850743 0.223161606577855 0.8234097319589466 1.0 1.0 12 O75381,Q9Y487 2 +Abnormality of peripheral nerves 0.3268177085958111 0.2198439602805297 0.825992681695578 1.0 1.0 48 P07602,Q9NZJ7,O15269,Q9Y619,Q9NR77,O95831,Q7LG56,Q99720 8 +Abnormality of thalamus morphology 0.3240812830816993 0.2191666728079499 0.8265202156052909 1.0 1.0 17 O75306,Q13509 2 +Irregular femoral epiphysis 0.504920231310305 0.2190916604941657 0.826578646930415 1.0 1.0 3 Q9NUQ7 1 +Delayed eruption of primary teeth 0.6239900559353736 0.2187918941605877 0.8268121614309454 1.0 1.0 2 Q13045 1 +Abnormality of the upper arm 0.3102761116500098 0.2186571644110455 0.826917119334746 1.0 1.0 21 P50402,O14979,Q7RTS9,P50542,Q9BV10,P16435,O15228 7 +Tetraparesis 0.3275880063503937 0.2184424297628961 0.827084409481377 1.0 1.0 39 P07602,P35637,Q9NZJ7,Q7RTS9,Q9UBX3,P17900,P33897,Q9H9P8,P00846,Q96B26 10 +Abnormal glial cell morphology 0.3232099275200775 0.2174974127330412 0.8278207230828745 1.0 1.0 53 O75306,Q10713,P35637,P04062,O95831,Q9H9P8,P00846,Q16134 8 +Progressive night blindness 0.3322881182428737 0.217423063779397 0.8278786587825309 1.0 1.0 15 Q10713 1 +Subvalvular aortic stenosis 0.4194651741293442 0.2149745515491942 0.8297871596240565 1.0 1.0 4 Q06124,O43684,O60566 3 +Abnormal left ventricular outflow tract morphology 0.4194651741293442 0.2149745515491942 0.8297871596240565 1.0 1.0 4 Q06124,O43684,O60566 3 +Abnormal nervous system electrophysiology 0.3339748330994002 0.2139575948266763 0.830580125825068 1.0 1.0 192 Q86SQ9,Q15125,P48449,P21281,P03886,Q9Y619,Q96A33,Q9P0S2,P50897,O15269,Q9NZ01,Q9BQE5,O95831,P07196,Q99720,Q9NQZ5,Q96N66,P07602,Q15067,O75503,P13073,O14773,O43292,P21964,Q9Y5Y5,O96028,Q14108,Q9UBX3,Q9NZJ7,Q9H2C2,Q9NR77,O43175,Q7LG56,O75381 34 +Hypoplasia of the frontal lobes 0.3607855455745326 0.2133545685047386 0.8310504137059413 1.0 1.0 9 Q86XL3 1 +Blue irides 0.3670614432805797 0.2111860417540287 0.8327421022003696 1.0 1.0 8 P10644 1 +Multifocal epileptiform discharges 0.3175382674611545 0.2095761713191318 0.8339984791469108 1.0 1.0 27 Q96N66,O75503,Q9UBX3 3 +Cardiomegaly 0.3252601015405366 0.2095367315475041 0.8340292641122811 1.0 1.0 36 Q9Y4P3,P23786,P04062,P04066,P10253,P54802,P10644,Q14739 8 +Progressive leukoencephalopathy 0.6177750155376113 0.2074474913056174 0.8356603964712552 1.0 1.0 2 Q5JTZ9 1 +Infantile muscular hypotonia 0.2957879183845477 0.2071719540542621 0.8358755695704758 1.0 1.0 70 O75306,P07602,P21281,Q9Y487,P03886,Q9NZJ7,P10253,P49748,P00846,Q13510,Q13509 11 +Limb undergrowth 0.3240344088512821 0.2054450426213258 0.8372244318000939 1.0 1.0 50 Q03164,Q15125,Q7RTS9,Q96HY6,O43175,P10644,Q9BV10,Q14739,Q9UBM7,P98175,Q15392,Q9UHX1 12 +Apraxia 0.2999372178705835 0.2054222115847269 0.8372422679630733 1.0 1.0 68 P05067,P35637,Q9NQT5,Q15233,P04062,Q9Y619,Q13509,Q6DKK2,Q7LGA3,O96008,P40763,Q9Y2B2,Q9BPU6,Q10713,P42356,O75787,O14773,Q9BVA1,O75648,O43292,Q8N3R9,Q9H270,P11166,P33897,O43924 25 +Abnormal ureter morphology 0.3126902827327606 0.2038169888830868 0.8384965162968994 1.0 1.0 24 P23786,O75844,Q7LGA3,O76024,Q8TAA9 5 +Atypical absence seizure 0.6155997513983944 0.203575528175951 0.838685218347375 1.0 1.0 2 Q96CW1 1 +Dilation of virchow robin spaces 0.6155997513983944 0.203575528175951 0.838685218347375 1.0 1.0 2 P27635 1 +Pectus excavatum 0.2717397687280387 0.1996499090035517 0.8417543917547281 1.0 1.0 79 O75718,P04062,Q96A33,Q9Y4P3,Q8NCH0,Q7LGA3,Q15555,O75431,P98175,Q99643,Q9Y487,Q9Y2B2,P51812,P42356,Q9UHX1,Q03164,P50402,Q9H490,Q9NSD9 19 +Hypoplasia of the musculature 0.3707145067023922 0.1981819236868106 0.8429027297989413 1.0 1.0 7 Q9NR77 1 +Bulbous nose 0.3253739901875228 0.1979366691734518 0.8430946138720659 1.0 1.0 43 Q9Y2B2,P42892,P21281,Q96EK5,P23786,Q02252,Q96A33,O00192,O75845,P16435,P21964 11 +Atrial arrhythmia 0.3495147558705326 0.1973928290519658 0.8435201408157118 1.0 1.0 10 Q7LG56,P12235 2 +Abnormal pattern of respiration 0.3226008370159857 0.1971580877809943 0.84370382791725 1.0 1.0 175 P35637,P21281,P03886,P04062,Q9Y619,Q96A33,P35610,P53701,P00846,Q96CU9,P06280,P51798,O75306,O75844,P23786,Q92804,Q86Y39,O75419,P49748,Q15165,O95831,Q13510,O76024,P98175,Q96EY8,P07602,Q10713,Q7KZN9,P51812,O43772,P10644,Q9UHX1,Q9NZJ7,P10253,P12235,P22695,Q7LG56,Q16134,O43924,Q9NSD9 40 +Abnormality of lower limb epiphysis morphology 0.315527151147945 0.1964970607956433 0.844221132971245 1.0 1.0 18 Q7RTS9,Q7LGA3,P50542,O95831,Q9NUQ7 5 +Truncal obesity 0.3318874747955572 0.1954738204106609 0.845022030634536 1.0 1.0 14 Q10713,P31751 2 +Heinz bodies 0.6109384711000727 0.1954510495700531 0.8450398553617446 1.0 1.0 2 P11413 1 +Hypertension associated with pheochromocytoma 0.3630413811206145 0.1950678074343003 0.8453398643745569 1.0 1.0 8 P10644,Q99643 2 +Elevated calcitonin 0.3630413811206145 0.1950678074343003 0.8453398643745569 1.0 1.0 8 P10644,Q99643 2 +Intestinal polyp 0.3151592623441103 0.1943010894377352 0.8459401326431473 1.0 1.0 18 P42892,O60566,P33897,Q99643 4 +Severe muscular hypotonia 0.3193082960096063 0.1923926166565361 0.8474346754267421 1.0 1.0 31 Q9NWM8,Q9Y5Y5,O43505,O95831,O75381 5 +Abnormality of the abdominal wall 0.2764914283049548 0.1897724750619903 0.8494874256412785 1.0 1.0 107 Q9Y4P3,Q9NWM8,P21964,Q10713,Q9NSD9,O75844,Q8NCH0,P04066,P51812,O00192,O43175,Q9BUB7,Q14739,Q9ULK5,Q9UBM7,Q9UHX1,Q9Y487 17 +Abnormal aortic valve morphology 0.3240042322254466 0.1893996523804242 0.8497795968980282 1.0 1.0 40 Q9Y4P3,P21964,O75844,P04062,P51812,Q9BUB7,Q9UHX1,P06280 8 +Abnormality of limb epiphysis morphology 0.3186788564472677 0.1880021645112064 0.8508749544025376 1.0 1.0 31 Q5JRA6,O96028,O43909,Q7RTS9,Q7LGA3,P50542,P51812,P10644,O95831,P16435,Q9NUQ7,O15228 12 +Aplasia involving bones of the extremities 0.48678893378925 0.1832846938908275 0.8545746434729093 1.0 1.0 3 Q9BXW9,P02545 2 +Blue sclerae 0.3108718199559616 0.1823819054432587 0.855283025018994 1.0 1.0 25 Q8NCH0 1 +Rod cone dystrophy 0.3233070469778905 0.1821908037189312 0.8554329897834274 1.0 1.0 44 Q86SQ9,Q9Y5Y5,P38435,P03886,Q15067,P00846 6 +Abnormality of the adrenal glands 0.3151878688191038 0.1814728379755809 0.8559964513226361 1.0 1.0 57 P56589,Q13423,Q9Y5Y5,P21281,O75844,P50542,P21912,O95470,P10644,P33897,O75381,Q9ULK5,P16435,Q99643 14 +Neonatal hypoglycemia 0.3528197615918376 0.1795156361155984 0.85753284090805 1.0 1.0 9 P31751 1 +Missing ribs 0.3319422780963473 0.1791838041204743 0.8577933803566555 1.0 1.0 13 Q14739,Q8TAA9 2 +Abnormal heart valve physiology 0.2812012179865193 0.1787656417978415 0.8581217245254535 1.0 1.0 75 O75306,Q9Y4P3,Q15125,P00813,P16278,O75844,Q9NX14,P04062,P51812,O75431,P10644,P53701,O60566,Q9NZ08,Q9UHX1,P06280 16 +Diaphragmatic eventration 0.4830587503885644 0.1763983490728422 0.8599810015780163 1.0 1.0 3 P08243,O60568 2 +Abnormal abdomen morphology 0.3482542357404213 0.1753562116709788 0.8607997454250436 1.0 1.0 223 P56589,O43676,Q86SQ9,P21281,P03886,O15118,P04062,Q9Y619,Q96A33,Q9HC21,P35610,P10619,P31751,Q9NVI7,Q9BUB7,Q9NZ08,P00846,Q01844,Q96CU9,Q15392,Q9BT22,P51798,O75306,P00813,P23786,Q86Y39,P04066,P49748,Q9NPL8,Q14739,Q5HYI8,Q13510,Q9UJW0,P00374,Q96EY8,P07602,Q10713,Q9HC07,P28070,Q15067,O43772,P10644,O75845,Q9Y6M9,P21964,Q9Y5Y5,Q14108,Q9NZJ7,P10253,P54802,O00192,P11166,Q96HY6,O75381,Q16134,Q9NSD9 56 +Postnatal growth retardation 0.3073927074235101 0.1710315025671409 0.8641989950688131 1.0 1.0 62 Q03164,Q15125,O96028,Q9Y487,Q7RTS9,Q9NP80,P11166,P17900,O75431,O76024,P10644,O60566,Q13509 13 +Irregular epiphyses 0.3677641856132441 0.1693923945585767 0.8654880053262433 1.0 1.0 6 Q7RTS9,Q9NUQ7 2 +Neonatal death 0.3193569037559896 0.1679494524232768 0.8666230452229111 1.0 1.0 16 P04062,Q9NVI7,Q9NX14,Q14739,Q16134 5 +Small earlobe 0.3620484460020494 0.1669575315587924 0.8674034647278226 1.0 1.0 7 O00192,P98175,P21964 3 +Emg neuropathic changes 0.3110511492798036 0.1659492378444101 0.86819689846625 1.0 1.0 27 P07602,Q9NZJ7,Q9NR77,O14773,Q13510 5 +Limited extraocular movements 0.3552886161799753 0.1648116824905705 0.8690922084948538 1.0 1.0 8 O75306,Q9UHD1 2 +Optic nerve hypoplasia 0.3001056184210023 0.1647088957113147 0.8691731148526074 1.0 1.0 20 Q9UHX1,Q9NVI7,Q13509 3 +Carcinoid tumor 0.4755983835871968 0.1631230023551807 0.8704215891033649 1.0 1.0 3 P49815,P02545 2 +Restlessness 0.3195378199865483 0.1607301643834092 0.8723059305661098 1.0 1.0 38 P42892,P48449,P05067,P35637,Q92804,Q6PJG6,P04062,O96008,P35610,P10644,Q15165,Q6Y7W6 12 +Craniosynostosis 0.3184970587865361 0.1602882985247031 0.8726539761229493 1.0 1.0 36 P51798,P21281,O15047,Q8NCH0,Q9Y619,O75419,O00192,P16435,P21964 9 +Midface retrusion 0.2715156040835454 0.1600370984015252 0.8728518505306222 1.0 1.0 78 Q15125,Q9HC07,Q96A33,P10644,Q9BV10,O95831,P53701,Q14739,P55795,Q9Y487 10 +Moderate albuminuria 0.4735444041747037 0.1595848296316332 0.8732081300158496 1.0 1.0 3 Q5JRA6 1 +Acne 0.3327115686901706 0.1578522861551227 0.8745731967017172 1.0 1.0 11 Q9NZ08,P21964 2 +Abnormal atrioventricular valve physiology 0.320075560373399 0.1568665390842017 0.8753500312699736 1.0 1.0 44 O75306,Q9Y4P3,O75844,Q9NX14,P04062,P51812,O75431,P10644,P53701,Q9NZ08,P06280 11 +Excessive wrinkled skin 0.3401869158878462 0.1558899406859118 0.876119774539591 1.0 1.0 10 P38606,O60832,Q06124,P36543,P32322,Q02750,O95453,Q02809,Q9Y487 9 +Dysphagia 0.2942879251410897 0.154481577143016 0.8772300361574334 1.0 1.0 136 P35637,P03886,O15118,P04062,P00846,O75306,Q14739,Q13510,O76024,Q99643,Q99720,P07602,Q15067,Q9UHX1,Q9Y5Y5,Q03164,Q14108,Q9NZJ7,P12235,Q9NR77,Q7LG56 21 +Thick eyebrow 0.3191615904966722 0.1529762335306531 0.8784170175660437 1.0 1.0 40 Q03164,P21281,Q96EK5,P04066,O95831,P98175,Q9UHX1 7 +Pseudoepiphyses 0.3702597171651305 0.1526451757997139 0.878678097301643 1.0 1.0 5 O96028,P51812 2 +Accessory spleen 0.3571731864182358 0.1499911193995233 0.8807716216908497 1.0 1.0 7 Q96J42,Q15904,O96028 3 +Polycystic kidney dysplasia 0.3159701916962837 0.1495461466980333 0.8811226989296732 1.0 1.0 16 P23786,O00192,Q16134,P21964 4 +Bifid tongue 0.3689947048336643 0.1491795078396443 0.8814119894203352 1.0 1.0 5 P61978,Q9UBM7 2 +Genetic anticipation 0.5811062771908063 0.149031069833028 0.8815291165426051 1.0 1.0 2 P54886 1 +Dilated fourth ventricle 0.3190350862411771 0.1487024696332881 0.8817884124214015 1.0 1.0 43 Q15125,Q10713,P21281,P23786,Q96J42,O43175,O43505,Q9UBM7,Q9Y487 9 +Abnormality of skeletal muscle fiber size 0.3154943009641609 0.146984366556733 0.8831443599711841 1.0 1.0 16 O95831 1 +Hypermethioninemia 0.3908582089552165 0.1468495088801421 0.8832508058129913 1.0 1.0 4 P55263,Q6PGP7,Q9UJS0 3 +Pheochromocytoma 0.3446253972136223 0.1459895849202027 0.8839296103668386 1.0 1.0 9 P10644,Q99643 2 +Hyperkinetic movements 0.3301183737031908 0.1457925638124696 0.8840851463972856 1.0 1.0 11 P07602 1 +Abnormality of the pubic bone 0.3559205952702821 0.1457039906924666 0.8841550708765837 1.0 1.0 7 Q7RTS9,O96028 2 +Delayed ossification of carpal bones 0.4642843637080623 0.1442610135702703 0.8852943628856407 1.0 1.0 3 Q9NUQ7 1 +Diminished motivation 0.300316570034636 0.1442559668052954 0.8852983479395107 1.0 1.0 22 P35637,P04062,P35610,P17900,P06865 5 +Paronychia 0.4637861361517038 0.1434656551112186 0.8859224338728144 1.0 1.0 3 P40763,Q9H4A3 2 +Painless fractures due to injury 0.4637861361517024 0.1434656551112164 0.8859224338728162 1.0 1.0 3 Q9H4A3,P39210 2 +Abnormal cranial nerve physiology 0.2831661635854539 0.1433300775877937 0.886029502582812 1.0 1.0 73 P51798,Q9Y5Y5,P07602,Q7LG56,P07196,Q9NZJ7,O75381,P12235,Q9NR77,Q9NZ08,Q9UHX1,Q13510,Q99643,Q13509 14 +Iris coloboma 0.3127647106024933 0.1408748818885206 0.8879687855816409 1.0 1.0 32 Q10713,Q96EK5,O43505,P53701,Q9UHX1 5 +Abnormal sella turcica morphology 0.3543995419410078 0.1405382460385318 0.888234736362274 1.0 1.0 7 Q7RTS9,O75431 2 +Reduced consciousness confusion 0.2856212596329947 0.1396303395899047 0.8889520679163865 1.0 1.0 125 O43676,P03886,P04062,Q9Y619,P35610,P31751,Q9NZ08,Q96CU9,O75306,Q13423,P23786,Q86Y39,O96008,P49748,Q9NPL8,Q96EY8,P07602,O43772,Q9Y6M9,Q9UBM7,Q9H3L0,Q9NZJ7,P12235,P11166,Q7LG56,Q16134 26 +Abnormal hdl cholesterol concentration 0.3866870819326504 0.137942670263052 0.8902857267455873 1.0 1.0 4 P38571 1 +Vertebral wedging 0.4598105405942232 0.1372255611212549 0.8908525071761162 1.0 1.0 3 Q8WVQ1 1 +Proximal amyotrophy 0.320514131489753 0.1370028637334524 0.8910285315258497 1.0 1.0 14 P07196,P35637,O14979 3 +Distal upper limb amyotrophy 0.3233065025962162 0.1364085419177592 0.8914983213247285 1.0 1.0 13 Q9NR77,Q9BQT8 2 +Pes cavus 0.2710508662739689 0.1356092413339859 0.8921301994191162 1.0 1.0 105 Q8NI60,Q10713,P21281,O00400,Q9H6K4,Q9BRK0,P04062,Q7LGA3,P05023,O15269,Q9NR77,O95831,P07196,Q14739,Q15907,Q99720 16 +Dry hair 0.4581908610506789 0.1347375031053047 0.8928194203529967 1.0 1.0 3 P46778,O60828 2 +Increased serum iron 0.4581908610506773 0.1347375031053021 0.8928194203529987 1.0 1.0 3 Q02241,Q6PGP7 2 +Aplasia hypoplasia of the distal phalanges of the hand 0.3096707079108782 0.1334149730465573 0.8938652044856434 1.0 1.0 30 P51798,Q9Y2B2,P21281,P38435,O75844,P16435 6 +Stroke 0.3105756713121436 0.1325183305421624 0.8945743252098812 1.0 1.0 31 O75844,P06280,O76024,P03886 4 +Hypomimic face 0.3271549305647426 0.1322005731251964 0.8948256478124095 1.0 1.0 11 Q7LG56,P04062,Q6Y7W6,P12235 4 +Cystoid macular edema 0.36252107556205 0.1318787084533063 0.895080229712824 1.0 1.0 5 Q86SQ9 1 +Abnormal macroscopic urine appearance 0.2946833143672614 0.1312898226557427 0.8955460424475066 1.0 1.0 20 P23786,Q9BW27,Q8NFH4,Q8N1F7 4 +Food allergy 0.3830845771144211 0.1304656994060894 0.8961979900659711 1.0 1.0 4 Q6P1M0,Q01082,O95394 3 +Trichorrhexis nodosa 0.4547715262667149 0.1295877613225007 0.8968925866426336 1.0 1.0 3 Q6PGP7,Q15477 2 +Bilateral cleft lip 0.4544606776499912 0.1291265145400399 0.8972575420679514 1.0 1.0 3 O60716,Q9NXE4 2 +Abnormal eosinophil morphology 0.3448500152077176 0.125901084154795 0.8998102244748236 1.0 1.0 8 O43909,P00813 2 +Hypoplastic fingernail 0.3149764098460009 0.1253534511194075 0.9002437379797867 1.0 1.0 15 Q14739,P21281,P51812 3 +Aplasia hypoplasia of the 5th finger 0.3149353871105444 0.1251443243784549 0.9004092933145289 1.0 1.0 15 P13073,Q9UHX1 2 +Abnormal nasolacrimal system morphology 0.3208753272819108 0.1246932759545183 0.900766380864447 1.0 1.0 13 Q9NX14,P53701,O43175,Q6NUK1 4 +Plagiocephaly 0.312713910668875 0.1238909065893962 0.9014016529674832 1.0 1.0 35 Q10713,P21281,Q96A33,Q01105,Q9BV10,Q13509 6 +Minimal change glomerulonephritis 0.317818631776382 0.1236152613330175 0.9016199083741818 1.0 1.0 14 Q9BW27,Q8NFH4,Q8N1F7 3 +Status epilepticus 0.3136332853386029 0.1229925711086543 0.9021129806988836 1.0 1.0 51 Q86SQ9,P42892,P07602,Q9NZJ7,Q9H2C2,O43292,Q01105,P53701,Q13510,Q15392,Q9Y487 11 +Impaired tactile sensation 0.3385826268409839 0.1221547040819103 0.902776498630242 1.0 1.0 9 Q9NR77 1 +Hypogonadotropic hypogonadism 0.2982867216571245 0.1213263816566357 0.9034325248257968 1.0 1.0 23 Q7LG56,P03886 2 +Stenosis of the external auditory canal 0.3483978704996127 0.1205936962749884 0.9040128620464016 1.0 1.0 7 P16435 1 +Focal cortical dysplasia type ii 0.558110627719093 0.1197364761712429 0.9046919044049502 1.0 1.0 2 P49815 1 +Hemimegalencephaly 0.558110627719093 0.1197364761712429 0.9046919044049502 1.0 1.0 2 P49815 1 +Aplasia hypoplasia of the proximal phalanges of the hand 0.5581106277190869 0.1197364761712362 0.9046919044049556 1.0 1.0 2 Q9BXW9 1 +Juvenile myelomonocytic leukemia 0.4466894622319016 0.1179683158891535 0.9060927628031594 1.0 1.0 3 P22681,Q06124 2 +Myeloid leukemia 0.4466894622319016 0.1179683158891535 0.9060927628031594 1.0 1.0 3 P22681,Q06124 2 +Heterotropia 0.312257146878069 0.116606880364162 0.9071715851827892 1.0 1.0 52 P04062,O43175,Q9NVI7,Q7LG56,P55795,O43924,Q9UHX1,Q13509 8 +Malabsorption 0.3107430074657757 0.116076989086358 0.9075915255684124 1.0 1.0 54 P56589,Q9Y4P3,P09601,Q9Y5Y5,O75381,P50542,Q96A33,Q9Y6B6,Q9NZ08,Q14739,P38571,O76024,Q9UJW0,P06280 14 +Coarse facial features 0.3054418579203187 0.113701279011678 0.9094745985938308 1.0 1.0 59 Q9Y4P3,Q9Y2B2,P21281,Q7RTS9,Q7LGA3,P04066,Q96A33,P54802,P10619,O95831,P06280 11 +Accelerated skeletal maturation 0.3363413821894705 0.1135145685256467 0.909622613721106 1.0 1.0 9 Q03164 1 +Aplasia hypoplasia affecting the eye 0.2627679323367271 0.1133911528333479 0.9097204534910897 1.0 1.0 96 Q15125,Q9NVI7,P53701,O60566,Q13509,Q9Y4P3,Q7LGA3,Q15555,Q96J42,Q12797,P07196,Q99643,Q9NX14,Q9UBM7,P21964,Q9UHX1,O96028,Q02252,Q6NUK1,O00192,P11166,O43175,O43505,O43924 24 +Aplasia of the semicircular canal 0.5518955873213307 0.1127566942866389 0.910223452262467 1.0 1.0 2 P22681 1 +Morphological abnormality of the vestibule of the inner ear 0.5518955873213307 0.1127566942866389 0.910223452262467 1.0 1.0 2 P22681 1 +Cerebral calcification 0.3094483107687331 0.1122903501674646 0.9105931928635628 1.0 1.0 33 P03886,P23786,O43175,O75845,Q9NSD9 5 +Abnormal circulating iga level 0.3206303680243089 0.1120924522121908 0.910750101972059 1.0 1.0 12 P00813,Q15904,Q9BV10 3 +Abnormality of facial soft tissue 0.2800501389600482 0.111913168740184 0.9108922550551632 1.0 1.0 120 P56589,Q12769,P04062,P50542,Q15907,Q13509,P51798,Q9Y4P3,O75844,P07196,Q13510,Q99643,P28070,Q9BQT8,P51812,P42356,P16435,Q8N1F7,Q6Y7W6,Q9UHX1,Q9UBM7,Q9Y5Y5,O75381,Q9BW27,P10253,P12235,Q8NFH4,P33897,Q7LG56,P21912 30 +Abnormal spermatogenesis 0.3225711858064011 0.1115884869785181 0.9111497010648462 1.0 1.0 11 Q13423,P04062 2 +Aplasia of the phalanges of the hand 0.550652579241778 0.1114073614955876 0.9112933227734588 1.0 1.0 2 Q9BXW9 1 +Labial hypertrophy 0.550652579241778 0.1114073614955876 0.9112933227734588 1.0 1.0 2 O15120 1 +Late onset 0.3293109573784849 0.1098569091997799 0.912522857105476 1.0 1.0 10 P31751 1 +Abnormal blood monovalent inorganic cation concentration 0.2959594872367385 0.1096826470307738 0.9126610630366438 1.0 1.0 19 Q13423,P05023,Q9BV10 3 +Dysphasia 0.3083707242761148 0.1093812922512749 0.9129000713314246 1.0 1.0 16 O00192,P53701,Q9H9P8,P21964 4 +Short upper lip 0.3718516015971105 0.1084448096984672 0.9136428576988908 1.0 1.0 4 O96028 1 +Esophageal neoplasm 0.3475778072200388 0.1077486113362956 0.9141951076759902 1.0 1.0 6 Q99643 1 +Impairment of activities of daily living 0.3088442707159635 0.1069495873398949 0.9148289737452222 1.0 1.0 55 P07602,P35637,O75298,Q9NZJ7,O15269,P51812,O00192,P07196,Q9ULK5,Q8TAA9,P21964,Q99720 12 +Primary microcephaly 0.3077665032447505 0.1062579965426997 0.9153776567613204 1.0 1.0 16 O43175 1 +Epidermoid cyst 0.4376748523469151 0.1059165785562876 0.9156485402722534 1.0 1.0 3 O60716,P49815 2 +Elevated hemoglobin a1c 0.3690920398009852 0.1033359547879782 0.9176963405574824 1.0 1.0 4 Q9UKG1,O75431,Q96MF7 3 +Neuroendocrine neoplasm 0.3206150313731164 0.1029488073074646 0.9180036008272944 1.0 1.0 11 P10644,Q99643 2 +Abnormality of the gingiva 0.3127534942432394 0.1008634860760715 0.919658829132166 1.0 1.0 45 Q9Y4P3,P21281,Q14108,P04062,P10644,O75845,Q14739,Q15392 8 +Abnormal circulating igg level 0.3157980604983263 0.1007167288550694 0.9197753311958916 1.0 1.0 13 O43909,P00813,Q9BV10 3 +Cerebral cortical atrophy 0.2616965391882796 0.0989476623588235 0.9211798254673156 1.0 1.0 96 Q9Y4P3,Q9Y2B2,P03886,P04062,Q7LGA3,Q9Y619,O96008,O75503,P51812,O76024,Q9BUB7,P00846,O43924,Q96B26 14 +Paralysis 0.3119666843775547 0.0989143451156076 0.9212062790090624 1.0 1.0 48 P51798,P50402,P35637,Q92804,P04062,P10253,Q9HC21,P11166,Q9NR77,P42356,P17900,Q15165,P21912,Q99643 14 +Limb hypertonia 0.3122476608329649 0.0984569811356427 0.921569430013383 1.0 1.0 42 O00400,Q15125,Q9H2C2,Q14739 4 +Enlarged posterior fossa 0.3110940201858981 0.0979647946849237 0.9219602486305682 1.0 1.0 50 Q15125,Q10713,P21281,P23786,P49748,Q96J42,Q9NPL8,O43175,O43505,Q9H490,Q9Y487 11 +Abnormal adipose tissue morphology 0.3008359425273721 0.0946850098898111 0.9245650248542634 1.0 1.0 61 O75844,P28070,P04066,P31751,O43175,Q9BV10,Q9ULK5,Q8TAA9,Q99643 9 +Vertebral fusion 0.316772754150105 0.0946225518432718 0.9246146364233404 1.0 1.0 12 Q8TAA9,Q9UHX1 2 +Abnormal circulating copper concentration 0.3427407721641891 0.0941248423128719 0.9250099866707604 1.0 1.0 6 Q9Y487 1 +Dyscalculia 0.3358154781939422 0.0940309235397847 0.9250845921248438 1.0 1.0 8 P35637 1 +Sepsis 0.2931905157208106 0.0939039143094857 0.9251854844108048 1.0 1.0 19 P42892,Q9BV10,Q9BT22 3 +Abnormality of coagulation 0.2991330738678165 0.0916481714631301 0.9269775771781276 1.0 1.0 62 Q9Y5Y5,P38435,Q9Y619,Q9P0S2,P10644,Q9BV10,Q5XKP0,P51571,O75381,Q9Y487 10 +Cerebral visual impairment 0.2891050363911362 0.0910853539366412 0.9274247701285724 1.0 1.0 68 Q96N66,P03886,Q5BJH7,Q96A33,P12235,Q9NZ01,Q01105,O43175,Q7LG56,Q96CU9,Q9H490 11 +Aplasia hypoplasia of the earlobes 0.3347656382719586 0.0904411285627403 0.9279366747244908 1.0 1.0 8 O00192,P98175,P21964 3 +Skin plaque 0.3413903330677551 0.0904034153824215 0.927966642726046 1.0 1.0 6 P16615 1 +Membranoproliferative glomerulonephritis 0.5282784338098339 0.0896875407036325 0.9285355171160968 1.0 1.0 2 Q03252 1 +Allergic rhinitis 0.5282784338098333 0.0896875407036323 0.9285355171160972 1.0 1.0 2 Q6P1M0 1 +Abnormality of the thymus 0.3075094713361892 0.0880602606212317 0.929828781061067 1.0 1.0 15 O00192,Q9ULK5,P00813,P21964 4 +Neonatal hyperbilirubinemia 0.4227541187441804 0.0880317941672427 0.9298514061390613 1.0 1.0 3 P36551,P43034 2 +Cellulitis 0.360074626865664 0.0874706063366992 0.93029744860431 1.0 1.0 4 P40763,P52732,P02545 3 +Caesarian section 0.3591417910447687 0.0859017043512012 0.9315445566446984 1.0 1.0 4 P33991,O60313,Q96EY7 3 +Wide nasal ridge 0.359141791044768 0.0859017043512 0.9315445566446994 1.0 1.0 4 P61978,P27635,Q15022 3 +Ectopia pupillae 0.3582360691641365 0.084391352729972 0.9327452822832072 1.0 1.0 4 O96028 1 +Open mouth 0.3007284691460633 0.0827771118170753 0.9340287687801824 1.0 1.0 29 Q10713,Q86XL3,P21281,Q15233,P61978,O43909,P04350,P04062,P51812,P10644 10 +Focal tonic seizure 0.5195773772529666 0.0824984860336054 0.934250322202538 1.0 1.0 2 Q9H936 1 +Generalized neonatal hypotonia 0.338304529277143 0.0820358809838666 0.9346181807047942 1.0 1.0 6 Q9Y5Y5 1 +Abnormal circulating sex hormone concentration 0.2951650868783613 0.0807174182267756 0.9356666842744004 1.0 1.0 18 Q13423 1 +Abnormality of the ureter 0.2947529725740742 0.0782402851419553 0.9376369173074752 1.0 1.0 64 Q9Y4P3,Q9Y2B2,P21964,Q86XL3,O75844,P23786,Q7LGA3,O75419,Q96J42,P16435,Q9UBM7,O76024,Q8TAA9,Q9UHX1 14 +Cerebellar malformation 0.3002781242120639 0.0776507533781469 0.9381058688686936 1.0 1.0 60 Q9Y4P3,Q86SQ9,Q15125,P21281,P23786,O75419,Q96J42,O43175,O43505,O75845,P16435,Q8TAA9,Q9Y487 13 +Renal hypoplasia aplasia 0.2621033936084005 0.0775808531142151 0.9381614734705914 1.0 1.0 79 O75306,P21964,Q9Y4P3,Q86XL3,Q7LGA3,O43175,P10644,P16435,Q8TAA9,Q9UBM7,O43924,Q15392,Q9UHX1 13 +Abnormal cranial nerve morphology 0.289618479253149 0.077358760981259 0.9383381464003836 1.0 1.0 67 P56589,P51798,P22626,Q9Y5Y5,Q7LG56,O75381,P50542,P12235,P51812,P21912,P42356,P10644,P07196,Q9UHX1,Q13510,Q99643,Q13509 17 +Increased muscle glycogen content 0.4121852657755764 0.0768723901486157 0.938725062005507 1.0 1.0 3 O75648,Q9BUK6 2 +Bifid uvula 0.3077838252816629 0.0768063818846044 0.9387775737289336 1.0 1.0 38 P21281,Q9Y619,O75419,O43175,O43505,Q15392,Q9C0D9 7 +Cerebral white matter hypoplasia 0.3362165019815526 0.0764820731552358 0.9390355757464484 1.0 1.0 6 P11166 1 +Preaxial foot polydactyly 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Rib segmentation abnormalities 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Hypoplastic pubic rami 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Abnormality of abdominal situs 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Craniofacial asymmetry 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Rieger anomaly 0.4113743017822471 0.0760663038866086 0.939366348048002 1.0 1.0 3 O96028 1 +Rectal prolapse 0.3256739852355739 0.0739445633934188 0.941054496423539 1.0 1.0 9 Q9Y4P3 1 +Abnormality of the parathyroid gland 0.2849826857902077 0.0739338951927082 0.9410629851803768 1.0 1.0 20 P10644,P21964,P03886 3 +Abnormal ilium morphology 0.2976955443344186 0.0732974326718915 0.9415694346377004 1.0 1.0 17 P16278,Q7RTS9,P50542,P51812,O95831,Q8TAA9 6 +Atrial flutter 0.5059042883778895 0.0725238955388264 0.9421849896473138 1.0 1.0 2 P02545 1 +Laryngeal stenosis 0.35041843693073 0.0718834002940295 0.9426947005176608 1.0 1.0 4 Q96HY6 1 +Movement abnormality of the tongue 0.3503192611859475 0.0717307837793439 0.9428161573429488 1.0 1.0 4 P10253 1 +Narrow foot 0.5043505282784476 0.0714881242358309 0.9430092758628936 1.0 1.0 2 O60828 1 +Abnormal natural killer cell morphology 0.3501243781094447 0.0714313287322837 0.9430544765623156 1.0 1.0 4 P33991,Q13546,O95394 3 +Reduced natural killer cell count 0.3501243781094447 0.0714313287322837 0.9430544765623156 1.0 1.0 4 P33991,Q13546,O95394 3 +Exertional dyspnea 0.2889273059458569 0.070119100474438 0.9440988641392822 1.0 1.0 19 O75844,P10644,P12235 3 +Abnormal chromosome morphology 0.502175264139232 0.070070353996366 0.9441376627702636 1.0 1.0 2 O95453 1 +Gingival overgrowth 0.2960412987695175 0.0700121413294008 0.9441839959688167 1.0 1.0 27 Q9Y4P3,P21281,Q6DKJ4,P16278,O43909,P10644,O75845,Q14739,Q9UBM7 9 +Hyperactive deep tendon reflexes 0.3193025411172563 0.0699405148748178 0.9442410058602696 1.0 1.0 10 P11166,Q9NR77,P21912 3 +Erythrocyte inclusion bodies 0.3482587064676551 0.0685940805226731 0.9453127308288324 1.0 1.0 4 Q9Y606,P11413,O14936 3 +Abnormality of the nasal septum 0.335152141660502 0.067059382725653 0.9465344289623588 1.0 1.0 5 P21281,P51812 2 +Limited elbow movement 0.3057356716610733 0.0667319591509033 0.9467950912873808 1.0 1.0 37 P50402,O43909,P23786,Q9H6K4,Q7RTS9,Q7LGA3,O14656,P48651,Q96J02,Q96AY3,Q969X5,P16435 12 +Brain neoplasm 0.4959602237414697 0.0662227778901035 0.9472004624430086 1.0 1.0 2 Q07864 1 +Sparse eyebrow 0.3002266023329492 0.0647517758739403 0.948371638098541 1.0 1.0 31 O75844,Q15125,Q96EK5 3 +Bradycardia 0.3114452447775145 0.0637572253833609 0.9491635381234766 1.0 1.0 11 O75208,Q6PJG6,O43772,O43464,Q9BTV4 5 +Cough 0.2901326342215131 0.0620922731775962 0.950489350237662 1.0 1.0 24 P04062,P35610,Q9NR77,P10644,Q9NSD9 5 +Aplasia involving bones of the lower limbs 0.4866376631448261 0.060993078479891 0.9513647213671416 1.0 1.0 2 P02545 1 +Abnormal thalamic mri signal intensity 0.3321928460342109 0.0608787597851849 0.9514557653000612 1.0 1.0 5 Q9GZY8,Q969Y2,Q969G3,Q96EY7 4 +Congenital diaphragmatic hernia 0.2826429998112093 0.0606028037997281 0.951675540521416 1.0 1.0 20 P53701,O96028,Q9ULK5,Q9UBM7 4 +Nocturnal seizures 0.4850839030453801 0.0601820486185425 0.9520106429240422 1.0 1.0 2 Q01082 1 +Moderately reduced visual acuity 0.3919801056885319 0.0588292033713536 0.9530881478091328 1.0 1.0 3 O00429,O60313 2 +Platybasia 0.3307035323127447 0.0578301862464546 0.9538838932603556 1.0 1.0 5 P21964 1 +Anteverted ears 0.4801118707271679 0.0576983647647686 0.9539888962567308 1.0 1.0 2 P27635 1 +Hypoplasia of the iris 0.3288414377803621 0.0575726562961821 0.9540890306488974 1.0 1.0 6 Q7LGA3 1 +Hoarse voice 0.287553183244098 0.0569233259424033 0.9546062730215144 1.0 1.0 23 Q9Y4P3,Q13510,Q99643 3 +Low back pain 0.4782473586078415 0.0568098410700118 0.9546966745601722 1.0 1.0 2 P54886 1 +Pulmonary carcinoid tumor 0.4754505904288539 0.055519720308166 0.9557244196454412 1.0 1.0 2 P02545 1 +Abnormality of cardiovascular system electrophysiology 0.2686486304710416 0.0550465810693861 0.9561013536973776 1.0 1.0 110 P42892,P03886,P04062,Q9BUB7,P53701,P00846,P06280,O75306,Q9Y4P3,O75208,P23786,P49748,Q99643,P07602,O43772,Q9Y5Y5,P50402,Q9NZJ7,P10253,P12235,Q7LG56,O75381,Q9H490 23 +Aplasia hypoplasia involving bones of the feet 0.2890727147758931 0.054463572934322 0.9565658300808486 1.0 1.0 66 Q9Y2B2,Q03164,P00813,O96028,P21281,Q7RTS9,Q7LGA3,Q96A33,P13073,P10644,Q13510,Q9UHX1,Q13509 13 +Phimosis 0.4729645742697491 0.0544150519412746 0.956604486907176 1.0 1.0 2 O60828 1 +Abnormal retinal morphology 0.3375357189544554 0.0542448655410514 0.9567400757486642 1.0 1.0 220 Q9Y287,Q86SQ9,P03886,P04062,Q9Y619,P10619,Q9NZ08,P00846,P53701,Q96CU9,P06865,P50897,O75306,Q9Y4P3,Q8NCH0,Q7LGA3,Q96J42,P51648,Q99757,Q9BV10,Q13510,O76024,Q9C0D9,Q99643,Q9Y487,Q9Y2B2,P07602,Q10713,Q15067,Q7KZN9,O75503,O14773,Q9UHX1,P21964,Q9Y5Y5,O96028,P38435,Q9NZJ7,Q9H2C2,O43505,Q5XKP0,Q7LG56,O75381,O43924,Q9UG56 45 +Abnormality of macular pigmentation 0.33768656716417 0.0535174572788018 0.95731962168392 1.0 1.0 4 Q9UM00,Q8NHS3,P55265 3 +Respiratory insufficiency 0.3152344155145691 0.0514019032118311 0.9590052682361856 1.0 1.0 181 O43676,P35637,P03886,Q70HW3,Q9Y619,Q9BUB7,P53701,Q96CU9,P06280,O75306,Q9BT22,O75208,P23786,Q92804,Q86Y39,O75419,P49748,Q9NPL8,Q15165,O95831,Q14739,Q13510,O76024,Q96B26,P07602,Q7RTS9,Q15067,O43772,Q9Y6M9,Q9Y5Y5,Q9NZJ7,P10253,P12235,Q9NR77,Q5XKP0,Q7LG56,O75381,Q9NSD9 38 +Pili torti 0.4580484773151194 0.0485702696518922 0.9612617633715824 1.0 1.0 2 P02545 1 +Cholangitis 0.4580484773151188 0.048570269651892 0.9612617633715828 1.0 1.0 2 Q96J02 1 +Urinary retention 0.3249613671142906 0.0480715585437231 0.961659212985334 1.0 1.0 6 Q8TAA9 1 +Diarrhea 0.2768629046275191 0.0477122133282163 0.9619456003611172 1.0 1.0 72 P42892,P03886,Q96A33,P35610,Q96J02,P50416,P15586,P06280,Q9BT22,Q13423,P00813,P36551,Q9Y6B6,Q5HYI8,Q13510,O43464,Q9UJS0,Q14691,Q15904,Q13546,Q16836,P54802,P33897,Q7LG56,P38571,Q14566 26 +Focal cortical dysplasia 0.3764376748523528 0.0476734782858667 0.9619764713237332 1.0 1.0 3 P49815,P42345 2 +Bilateral cleft lip and palate 0.4543194530764565 0.0473051719382244 0.9622700060887326 1.0 1.0 2 O60716 1 +Non midline cleft palate 0.4543194530764565 0.0473051719382244 0.9622700060887326 1.0 1.0 2 O60716 1 +Bilateral cleft palate 0.4543194530764565 0.0473051719382244 0.9622700060887326 1.0 1.0 2 O60716 1 +Femoral bowing 0.3213968064800088 0.0468891970373408 0.9626015381404208 1.0 1.0 8 Q7RTS9,Q9NVV0,P16435 3 +Abnormality of malar bones 0.2954313904046732 0.0448477632137596 0.964228653828743 1.0 1.0 61 Q15125,Q9HC07,P10644,O95831,Q14739,P16435,P21964,Q9Y487 8 +Dolichocephaly 0.2968900754652653 0.0437261343090324 0.9651227069695708 1.0 1.0 31 P56589,Q4J6C6,O95202,Q9Y5Y5,O96028,P21281,Q03164,P61978,Q7RTS9,P50542,P42356,Q969X5,O75381 13 +Vertical nystagmus 0.3698347876288875 0.0435912558056775 0.9652302219299108 1.0 1.0 3 P50542 1 +Hypomelanotic macule 0.4375388440024944 0.0424707968209117 0.966123391497972 1.0 1.0 2 P49815 1 +Abnormality of the humerus 0.297878037380183 0.0423839466145718 0.9661926255951192 1.0 1.0 15 Q7RTS9,P50542,Q9BV10,P16435,O15228 5 +Female sexual dysfunction 0.3226958087149249 0.0421501481619868 0.96637900321386 1.0 1.0 5 P33897,O75298 2 +Acanthosis nigricans 0.311837602723981 0.0418052429346226 0.9666539554112672 1.0 1.0 10 P28070,P31751 2 +Hallux valgus 0.2913734315766474 0.0414669859993395 0.9669236115615316 1.0 1.0 17 P04062,P21281 2 +Morning glory anomaly 0.4307022995649617 0.0408645133919857 0.9674039080137946 1.0 1.0 2 O60313 1 +Temporal optic disc pallor 0.4307022995649617 0.0408645133919857 0.9674039080137946 1.0 1.0 2 O60313 1 +Increased head circumference 0.2689474749393115 0.0400873951573017 0.9680234509322024 1.0 1.0 112 Q15392,Q13509,P51798,O75844,Q7LGA3,P49748,Q9H9P8,Q14739,Q99643,Q9Y2B2,P07602,Q10713,O15047,P51812,Q9Y5Y5,Q9NZJ7,P11166,O43505,O75381,Q16134 20 +Choriocarcinoma 0.4232442510876463 0.0393234056956749 0.9686325459992486 1.0 1.0 2 O96017 1 +Lung adenocarcinoma 0.4232442510876451 0.0393234056956749 0.9686325459992486 1.0 1.0 2 P30154 1 +Central primitive neuroectodermal tumor 0.4232442510876463 0.0393234056956749 0.9686325459992486 1.0 1.0 2 O96017 1 +Choroid plexus carcinoma 0.4232442510876463 0.0393234056956749 0.9686325459992486 1.0 1.0 2 O96017 1 +Hypoplastic nipples 0.3053131822022082 0.0388090762996235 0.9690426084468428 1.0 1.0 11 Q9Y2B2,P10586,Q96A33 3 +Localized osteoporosis 0.4204474829086462 0.0387982364572788 0.9690512508806824 1.0 1.0 2 P57740 1 +Metopic synostosis 0.3604312855650657 0.0384036760076729 0.969365830115512 1.0 1.0 3 P61978 1 +Deformed sella turcica 0.3202392893796231 0.0375803383344728 0.9700222845829976 1.0 1.0 5 Q7RTS9 1 +Aspiration pneumonia 0.2875575529207331 0.0374534112691756 0.9701234864819704 1.0 1.0 25 Q13510,P04062,P21281,P16278 4 +Eversion of lateral third of lower eyelids 0.4105034182722326 0.0371435480468021 0.9703705496480456 1.0 1.0 2 P61978 1 +Abnormality of skin pigmentation 0.2778314454665786 0.0363920772682278 0.9709697314206198 1.0 1.0 125 Q15125,P21281,P03886,P04062,P53701,O60566,P51798,Q13423,O75844,Q7LGA3,Q15555,P51648,O75431,Q8IZA0,Q14739,Q99643,P07602,P10644,P16615,Q9NX14,P21964,Q9NZJ7,Q06136,O00192,P33897,Q9H4L7 26 +Decreased circulating iga level 0.3198683510423051 0.0359534052815449 0.9713195121100932 1.0 1.0 7 P00813,Q15904 2 +Heterotaxy 0.3231484873804456 0.035497502178213 0.9716830380947116 1.0 1.0 4 O96028 1 +Eunuchoid habitus 0.3927905531386081 0.0349066223986706 0.9721541999224126 1.0 1.0 2 P04350 1 +Glomerular deposits 0.3903045369795002 0.0346549069238068 0.9723549183715552 1.0 1.0 2 P57740 1 +Abnormal metacarpal morphology 0.2965209488432259 0.0344866410097431 0.9724890949425896 1.0 1.0 32 Q8WVQ1,P16278,Q15233,O43909,Q7RTS9,P51812,O43924,P10644,Q14739,P16435,Q9NX62 11 +Abnormal circulating porphyrin concentration 0.3519020160202072 0.0342930400328602 0.9726434748562016 1.0 1.0 3 P22830 1 +Prominent antitragus 0.3837787445618535 0.0340569279440178 0.9728317550649536 1.0 1.0 2 Q92643 1 +Posterior pharyngeal cleft 0.3806712243629672 0.0338019648422716 0.973035069124855 1.0 1.0 2 P29372 1 +Reduced pancreatic beta cells 0.36886264760722 0.0329872824158436 0.9736847292850954 1.0 1.0 2 P40763 1 +Neurodegeneration 0.2939549715703186 0.0329637577381522 0.9737034890599016 1.0 1.0 30 Q8NHS3,P35637,Q13057,Q92804,Q6DKK2,Q99757,P17900,Q9UHD9,Q15165,P33897 10 +Sunken cheeks 0.3592293349906886 0.0324776645662338 0.974091127725832 1.0 1.0 2 P04350 1 +Smooth muscle antibody positivity 0.3365444375388549 0.0316868048289531 0.9747218178248772 1.0 1.0 2 Q96J02 1 +Medullary nephrocalcinosis 0.3194530764450084 0.0313542032182504 0.9749870637145096 1.0 1.0 2 O14656 1 +Phalangeal dislocation 0.3123057799875818 0.0312601854979728 0.9750620422481826 1.0 1.0 2 Q8WVQ1 1 +Advanced ossification of carpal bones 0.3123057799875818 0.0312601854979728 0.9750620422481826 1.0 1.0 2 Q8WVQ1 1 +Abnormality of the maxilla 0.296001866408073 0.0312477733652516 0.9750719408615284 1.0 1.0 32 Q96EK5,Q9Y619,O75419,P10644,Q14739 5 +Duplication of the distal phalanx of hand 0.29117464263519 0.0310852763385874 0.9752015317756366 1.0 1.0 2 Q8WVQ1 1 +Gonadoblastoma 0.2840273461777632 0.0310506662404315 0.975229133314624 1.0 1.0 2 P51809 1 +Ovarian gonadoblastoma 0.2840273461777632 0.0310506662404315 0.975229133314624 1.0 1.0 2 P51809 1 +Abnormal sex determination 0.2840273461777632 0.0310506662404315 0.975229133314624 1.0 1.0 2 P51809 1 +Hypoplasia of the vagina 0.2840273461777632 0.0310506662404315 0.975229133314624 1.0 1.0 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.2840273461777632 0.0310506662404315 0.975229133314624 1.0 1.0 2 P51809 1 +Abnormal protein glycosylation 0.2770570912953412 0.0296207698004488 0.9763695006749598 1.0 1.0 20 Q15904,Q9Y487,Q9BT22,Q8N511,P51571,O75340 6 +Thick corpus callosum 0.3403792353124072 0.029560691108383 0.976417415553787 1.0 1.0 3 O75175,Q15233 2 +Lymphocytosis 0.3366490519117262 0.0282153474350803 0.9774903966145652 1.0 1.0 3 O15143,Q03252 2 +Antineutrophil antibody positivity 0.3366490519117243 0.0282153474350798 0.9774903966145656 1.0 1.0 3 Q96J02,P61011 2 +Rheumatoid factor positive 0.3366490519117237 0.0282153474350795 0.9774903966145658 1.0 1.0 3 Q13546,O95394 2 +Small hand 0.2942095527265347 0.0271467275514098 0.9783427052815884 1.0 1.0 31 Q9Y619,Q96EK5 2 +Abnormal periventricular white matter morphology 0.3025128995340787 0.02540920071061 0.9797285723725891 1.0 1.0 44 Q53FT3,P07602,O96028,Q9NZJ7,O75503,P51571,Q9C0D9,Q9UHX1 8 +Abnormal fingernail morphology 0.3022741434564891 0.0241545714138461 0.9807293143064416 1.0 1.0 48 O75844,Q15125 2 +Impaired antigen specific response 0.3109011273915723 0.0236381968781627 0.9811412039525398 1.0 1.0 9 Q9BV10 1 +Arthropathy 0.3142173803480577 0.0233935852525667 0.9813363218342356 1.0 1.0 6 Q9Y3Z3,O15269 2 +Decreased activity of mitochondrial complex ii 0.3115656997053855 0.0223434793099335 0.9821739660546518 1.0 1.0 5 P21912 1 +Aplasia hypoplasia of the eyebrow 0.3002756423606437 0.0218871335177194 0.982537988283374 1.0 1.0 39 Q15125,P48449,Q96EK5,O75844,O75419,Q9NVI7 6 +Abnormal duodenum morphology 0.2978530347708321 0.0217151515808614 0.9826751774091896 1.0 1.0 13 Q8NCH0,P98175,O75419 3 +Submucous cleft soft palate 0.3077401305564246 0.0204099174698999 0.9837163725021728 1.0 1.0 3 O14802,Q15233 2 +Hyperacusis 0.3125024692359199 0.0202167566895683 0.9838704607121956 1.0 1.0 8 Q9Y4P3 1 +Connective tissue nevi 0.2994226076688833 0.0188850387436422 0.9849328147668706 1.0 1.0 3 Q6NUK1 1 +Arnold chiari malformation 0.2770072560762663 0.0185313829364875 0.9852149418976012 1.0 1.0 21 Q9Y4P3,Q86SQ9,O75419,P16435,Q8TAA9 5 +Aplasia hypoplasia of the vagina 0.2841156356854252 0.0167258179446381 0.986655350299008 1.0 1.0 3 P30153,P51809 2 +Acne inversa 0.2794529064345677 0.0162102119378509 0.9870666885863936 1.0 1.0 3 Q92542,Q9H488 2 +Coloboma 0.3010932879931696 0.0153004881650516 0.9877924530300546 1.0 1.0 44 Q9Y2B2,Q10713,O96028,Q96EK5,O43505,P53701,O43924,Q9UHX1 8 +Shyness 0.2670189617656245 0.0151013523200796 0.9879513220901612 1.0 1.0 3 Q06787,Q15233 2 +Abnormal libido 0.2489897419956509 0.0140386609467048 0.988799137095966 1.0 1.0 3 Q8WWQ0,P33897 2 +Neoplasm of head and neck 0.3077814505464383 0.0137166027222329 0.9890560776367324 1.0 1.0 9 P21912,Q99643 2 +Optic disc hypoplasia 0.3060653188180287 0.0134008885385843 0.9893079579545956 1.0 1.0 5 O14802,O94830,Q96KP1,O95721 4 +Male hypogonadism 0.3103360755021995 0.0116392545636603 0.9907134281636664 1.0 1.0 7 O76024 1 +Disproportionate tall stature 0.2889382150797233 0.0106967701309197 0.9914653750189584 1.0 1.0 29 Q9NWM8,Q8NCH0,Q7LGA3,P16435 4 +Peripheral cyanosis 0.3082448910025552 0.0081230925502247 0.9935187811450888 1.0 1.0 8 P04066 1 +Spinal canal stenosis 0.3063355604509734 0.006824717680101 0.9945547054019488 1.0 1.0 6 P10644 1 +Unsteady gait 0.2981509154258532 0.0063373732261885 0.9949435415933008 1.0 1.0 53 Q10713,Q9H6K4,Q9H2C2,O75503,Q9NR77,O95831 6 +Cranial asymmetry 0.3014191899991146 0.0062769642225007 0.9949917400459836 1.0 1.0 5 O96028 1 +Glossoptosis 0.3080996224542014 0.0062327478088246 0.995027018949668 1.0 1.0 7 Q9Y5Y5 1 +Thyroiditis 0.3060080554288389 0.0061644186320733 0.9950815366974772 1.0 1.0 6 P00813 1 +Hypopigmentation of the skin 0.2995900868248487 0.0032594384531343 0.9973993489862174 1.0 1.0 46 P51798,P21964,Q15125,P07602,Q9NZJ7,Q8IZA0,P53701,Q99643 8 +Skeletal muscle hypertrophy 0.2981904973142062 0.0013186097724461 0.9989479019257276 1.0 1.0 41 Q10713,P21281,Q7LGA3,P04066,Q96A33,P10253,Q9NR77,Q99643 8 +Kyphosis 0.2893240910078319 0.0012481736328945 0.9990041017877034 1.0 1.0 146 Q15125,P21281,P04062,Q13509,Q9BT22,Q9Y4P3,O75844,Q8NCH0,Q7LGA3,P04066,P51648,O95831,Q14739,Q99643,Q9Y487,Q9NWM8,Q9HC07,Q7RTS9,P51812,P10644,Q9UBM7,Q9UHX1,O96028,Q14108,Q9NR77 25 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..88fe9e13736e6a0f0421c0c4f4b239b057ed5779 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcification of the carpal bones", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Coronary artery stenosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglutaminemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Moderately short stature", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overgrowth of external genitalia", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Precocious puberty in females", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPAT2", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO10", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARV1", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATXN10", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCS1L", "BLVRA", "BMS1", "BRAT1", "BRD4", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CASK", "CAST", "CBL", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD2AP", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK6", "CELF2", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD4", "CHEK2", "CHMP1A", "CHMP4B", "CHORDC1", "CHST14", "CISD2", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNOT1", "CNOT2", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG4", "COG7", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ5", "COQ8A", "COQ9", "COX15", "COX16", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "CYP7B1", "DARS", "DARS2", "DAXX", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPAGT1", "DPF2", "DPM1", "DPYSL5", "DSG2", "DSP", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "EARS2", "EBP", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMC10", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GNAI3", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HAX1", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIKESHI", "HIST1H1E", "HK1", "HLA-A", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "INF2", "IRF2BPL", "IRS4", "ISCU", "ITCH", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRSAM1", "LSS", "LYRM7", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED17", "MED23", "MESD", "MFF", "MFN2", "MFSD8", "MGME1", "MGMT", "MIA3", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMADHC", "MOGS", "MPG", "MPI", "MPP5", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVK", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NEMF", "NFS1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUS1", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS2", "PEPD", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLD3", "PLEC", "PLOD1", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB11B", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASET2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS27", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRM2B", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SDHA", "SDHB", "SDHC", "SEC23A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENOI", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIN3A", "SIN3B", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC30A9", "SLC33A1", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SPART", "SPATA5", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQOR", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STUB1", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKT", "TMCO1", "TMEM126A", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOP3A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRMT1", "TRMT10C", "TRMU", "TSC2", "TSFM", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXN2", "TXNDC15", "UBA1", "UBE4B", "UBIAD1", "UBQLN2", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC45A", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VANGL2", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VMA21", "VPS11", "VPS13A", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR34", "WDR36", "WDR4", "WDR73", "WFS1", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "YAP1", "YARS", "YARS2", "YIF1B", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF148", "ZNF687", "ZPR1"], "leading_proteins": ["AARS2", "ABCB7", "ABCD1", "ABCD3", "ACADVL", "ACAT2", "ACOX1", "ACP2", "ADA", "ADAR", "ADD3", "ADK", "AGPAT2", "AIFM1", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALG1", "ALG12", "ANKLE2", "ANO10", "AP2M1", "APOL2", "APP", "APPL1", "ARL6IP1", "ARPC1B", "ARV1", "ARVCF", "ASAH1", "ASNS", "ASPH", "ATAD3A", "ATP1A1", "ATP2A2", "ATP2C1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "B4GAT1", "BCAP31", "BRAT1", "BUB1B", "BUB3", "C19orf70", "CANT1", "CASK", "CBL", "CCDC22", "CCDC47", "CCT5", "CDC45", "CERS1", "CHEK2", "CHORDC1", "CHST14", "CLCC1", "CLCN7", "CLN5", "CLPP", "CNOT3", "COA3", "COASY", "COMT", "COQ8A", "COQ9", "COX15", "COX16", "COX2", "COX4I1", "COX5A", "CPOX", "CPT1A", "CPT2", "CRTAP", "CSNK2B", "CTNND1", "CTSA", "DARS2", "DCTN4", "DDHD2", "DDRGK1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DIABLO", "DKC1", "DNAJC3", "DNM1L", "DPYSL5", "DYM", "EBP", "ECE1", "EIF4A3", "EMD", "ERAP1", "ERGIC1", "ETFDH", "EWSR1", "EXOC2", "EXOSC3", "EXOSC8", "EXTL3", "FANCD2", "FARSB", "FECH", "FKBP10", "FKBP14", "FLII", "FMR1", "FOXRED1", "FUCA1", "FUS", "G6PD", "GAA", "GBA", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLUD1", "GM2A", "GNPAT", "GNS", "GOSR2", "GPAA1", "GSR", "GTPBP3", "GUF1", "GYS1", "HADH", "HAX1", "HCCS", "HEXA", "HEXB", "HIKESHI", "HLA-A", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HS2ST1", "HTRA2", "IARS2", "IBA57", "IMPAD1", "ITCH", "ITM2B", "KDSR", "KIAA0319L", "KIF11", "KIF1A", "KIF23", "KIFBP", "KMT2A", "L2HGDH", "LAMP2", "LBR", "LETM1", "LIPA", "LMNA", "LMNB1", "LMNB2", "LSS", "MAP2K1", "MAPRE2", "MATR3", "MBOAT7", "MCM2", "MCM4", "MCM6", "MFF", "MFSD8", "MIA3", "MIF", "MIPEP", "MMAB", "MMADHC", "MPG", "MPP5", "MPV17", "MSH2", "MSH6", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTOR", "MTX2", "NAA10", "NAGLU", "NCSTN", "ND1", "NDUFA11", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS7", "NEFL", "NNT", "NONO", "NPC1", "NSD2", "NSMCE2", "NUP107", "NUP160", "NUP37", "NUP85", "NUP93", "NXN", "OPA1", "OPA3", "PAFAH1B1", "PARN", "PDCD6", "PDE6D", "PEX14", "PEX16", "PEX3", "PEX5", "PGM3", "PHGDH", "PHIP", "PI4KA", "PIGK", "PIGL", "PIGU", "PISD", "PITRM1", "PLD3", "PLOD1", "PLOD3", "PMPCA", "PNPLA8", "POFUT1", "POLE", "POLR3A", "PON2", "POR", "PPP2R1A", "PPP2R1B", "PPT1", "PQBP1", "PREPL", "PRKAR1A", "PSAP", "PSMB4", "PTCD3", "PTDSS1", "PTPN11", "PTPRF", "PUF60", "PUS1", "PXMP2", "PYCR1", "RAB11B", "RABL3", "RAPGEF2", "RBM10", "REEP2", "RINT1", "RIPK1", "RMND1", "RPL10", "RPL21", "RPS6KA3", "RRM2B", "RTN2", "SAMHD1", "SAR1B", "SC5D", "SCARB2", "SCO1", "SDHB", "SDHC", 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+Glycerophospholipid metabolism 9 20 2.7249988300002523 0.0064301714930208 5.553398058252427 16.104368932038835 0.8448777148315795 0.3373638196000335 3.045697762577092 2.514285464673758 1.2272389207362138 0.3056726473181033 0.0057864221222492 0.0286799036387023 0.0981876870196897 0.1411134338084059 0.0002308677663279 +Protein export 8 15 2.2518203581676803 0.024333626627607 4.822815533980583 15.32766990291262 0.4171726846718274 0.4878397660443146 2.560939571767388 1.0757302364075068 1.049330437992782 0.3330766219894535 0.0248830014547047 1.0 0.1871299927573601 0.0133829456596615 0.0003689915939861 +Oxidative phosphorylation 24 65 2.1658807443081693 0.0303203011023929 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 6.680335649849196e-05 0.0001409428662617 0.003364879438832 0.0001835775213899 8.685512602107174e-08 +Huntingtons disease 24 80 2.133057512721646 0.0329200085587104 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 0.0019921088920251 0.0059901365409964 0.0154677756890255 0.0032384967658702 0.0008831412078154 +Other glycan degradation 3 6 2.0501068413533146 0.0403540059425306 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 0.0006670086583305 1.0 1.0 0.2897526236095206 0.003721367796782 +Cardiac muscle contraction 6 21 2.047065382604736 0.040651665342942 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0115062578750082 0.1988423464133734 0.3588505448912167 0.0043649502990921 0.0055591316089767 +O glycan biosynthesis 2 5 2.0059604774205995 0.0448604649065733 1.5655339805825244 3.71116504854369 0.8243447291650007 0.3242728728546938 0.9466735098661064 0.6873133299563432 1.0938914110247178 0.2793328954524876 0.013913202095476 0.0802348466038066 0.1543818096433915 0.0621585272883563 0.0465653262864464 +Parkinsons disease 23 59 1.9929579499324264 0.0462660518265414 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 1.3971720494525533e-05 0.0001409428662617 0.000508180078871 3.6316852483644015e-05 8.347378531813546e-06 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7f4b6f3ebe7b8d39d4e8276b9c3f3aeb5741f4bf --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 16.544444444444444 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9d062abe120563245d5b701ff7a50786e4de0687 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5155048e90937cfa6e76c210363babfd79cf7f4c --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,61 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.6917498908589481 3.321806757755222 0.0008943661133493 0.1487572458125821 0.1609859004028859 48 O15118,P04062,P10619,P11117,P06865,P50897,P06280,Q15012,Q8NCC3,P04066,Q93050,Q9UMR5,Q13510,Q9Y487,P07602,O75503,O14773,Q14108,Q9NZJ7,P10253,P54802 21 +Sphingolipid metabolism 0.7950553869027934 2.824653195545616 0.0047331815659206 0.5742893281356457 0.2893577171859374 12 P16278,P04062,Q16739,O15269,O95470,Q13510,P06280 7 +Steroid biosynthesis 0.7932986365839338 2.815528914280275 0.0048697014666221 0.5846723189873797 0.2893577171859374 12 Q15125,P48449,Q16850,Q14534,P35610,Q15392,O75845,Q15800 8 +Glycerophospholipid metabolism 0.6585097819853039 2.7249988300002523 0.0064301714930208 0.6868798003439422 0.2893577171859374 20 Q96N66,Q9BVG9,Q9HBU6,Q8NF37,O95674,Q8NCC3,Q6P1A2,P35790,Q9UG56 9 +Protein export 0.6540277645523962 2.2518203581676803 0.024333626627607 0.9881357390840868 0.4383099646724976 15 Q15005,Q99442,P49458,P61009,P67812,Q9UHB9,Q15070,Q9Y5M8 8 +Oxidative phosphorylation 0.489349617748481 2.1658807443081693 0.0303203011023929 0.9960817277727504 0.4383099646724976 65 O43676,P21281,P03886,O14949,P00846,O75306,O95139,Q86Y39,Q93050,O75964,P14406,Q99643,Q9Y487,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9Y6M9,Q9Y6N1,P56385,O75251,P22695,P21912 24 +Huntingtons disease 0.4136941534745757 2.133057512721646 0.0329200085587104 0.9975832505094008 0.4383099646724976 80 O43676,O14949,P00846,P05141,P21796,O75306,O95139,Q9Y277,P45880,P14406,Q99643,Q9UJW0,P24539,Q9UDW1,P13073,O15514,O14548,Q9Y6M9,O75251,P12236,P12235,P22695,P21912,O75947 24 +Renin angiotensin system 0.8980368242476489 2.0713694252206087 0.0383242858900116 0.9991186330644506 0.4383099646724976 4 P10619 1 +Other glycan degradation 0.7863742234368082 2.0501068413533146 0.0403540059425306 0.9993974544954224 0.4383099646724976 6 P04062,Q9BTY2,P06865 3 +Cardiac muscle contraction 0.5586961096081025 2.047065382604736 0.040651665342942 0.9994301787003532 0.4383099646724976 21 Q9UDW1,P13073,P22695,P16615,O14949,P14406 6 +O glycan biosynthesis 0.811845449123434 2.0059604774205995 0.0448604649065733 0.9997417573841012 0.4383099646724976 5 Q8N4A0,O43505 2 +Parkinsons disease 0.4941777138647751 1.9929579499324264 0.0462660518265414 0.9998018913251406 0.4383099646724976 59 O43676,P03886,O14949,P00846,P21796,P05141,O75306,O95139,Q9Y277,P45880,P14406,Q99643,P24539,Q9UDW1,P13073,O14548,Q9Y6M9,O75251,P12236,P12235,P22695,P21912,O75947 23 +Snare interactions in vesicular transport 0.5631750260617849 1.9057934401228231 0.0566770103698686 0.9999725289430836 0.5100930933288175 18 O95249,O43752,Q9P2W9,O60499 4 +Glycosphingolipid biosynthesis ganglio series 0.771102638140878 1.556142567001324 0.1196741948493493 0.999999999891403 0.6630550421198877 4 O00400,P06865 2 +Glycosaminoglycan degradation 0.7057363355856265 1.5406791287140356 0.1233948989024231 0.9999999999493338 0.6630550421198877 5 P54802,P16278,P06865 3 +Calcium signaling pathway 0.5195491326127644 1.4714855944045482 0.1411598405160126 0.9999999999987288 0.6931452671032753 16 P05141,P12236,Q9Y277,P12235,P16615,Q9UHD1,P45880,P21796 8 +Riboflavin metabolism 0.688928046684737 1.4654039193283634 0.1428107487666317 0.9999999999991008 0.6931452671032753 5 Q9NPH0 1 +Biosynthesis of unsaturated fatty acids 0.5363318653793222 1.3652117064753149 0.1721865200562615 0.9999999999999984 0.7019295929140129 12 O00767,Q53GQ0,Q15067,O95864,O15254,Q9NZ01 6 +Nicotinate and nicotinamide metabolism 0.6648187744203465 1.356900770137212 0.174812742124248 0.999999999999999 0.7019295929140129 5 P43490 1 +Primary immunodeficiency 0.8461815278095779 1.333304712606272 0.1824318278060328 0.9999999999999998 0.7019295929140129 3 Q03518 1 +Glycosphingolipid biosynthesis globo series 0.8423601548785087 1.3189637706297357 0.1871812247770701 1.0 0.7019295929140129 3 P06865 1 +Steroid hormone biosynthesis 0.8349850209798357 1.2912936236294323 0.1966018808451557 1.0 0.7134566939196019 3 Q53GQ0 1 +Amyotrophic lateral sclerosis als 0.5234277259630697 1.2867472021125126 0.1981824149776672 1.0 0.7134566939196019 12 Q9BUN8,Q9UHD1,P07196,O96008 4 +Alpha linolenic acid metabolism 0.8178427105999272 1.2270436706506471 0.2198061775915523 1.0 0.7421991790895592 3 Q15067,O15254 2 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8063815662121745 1.1841663461895735 0.2363472211256563 1.0 0.7522464064637762 3 Q8NCH0 1 +Vibrio cholerae infection 0.4297793909645616 1.1042603980760806 0.2694801963663202 1.0 0.7579130522802757 20 Q93050,P24390,O43731,Q9Y487 4 +Fatty acid metabolism 0.4333229016166916 1.0838511570710123 0.2784307987186003 1.0 0.7710391349130471 29 Q9BWD1,P23786,Q15067,Q9UKU0,O15254,P35610,P30837,P51648 8 +Alzheimers disease 0.3926462395862694 1.0592981639146508 0.2894640108921473 1.0 0.7884830934554505 62 O43676,P05067,O14949,P00846,O75306,O95139,Q9UHD1,P14406,Q99643,P24539,Q9UDW1,P13073,P16615,O14548,Q9Y6M9,O75251,P22695,P21912,O75947 19 +Peroxisome 0.4229554801783982 1.0130992096775682 0.3110127757518721 1.0 0.7884830934554505 40 P56589,Q9Y5Y5,O75192,O14975,Q15067,P50542,Q9UKU0,Q96HA9,O15254,Q9NR77,O14734,P33897,O75381,O15228 14 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.5513533285759389 0.9498385636608132 0.3421942876351045 1.0 0.8323644834367407 6 Q9Y2B2,O43292,Q9H490 3 +Abc transporters 0.5308630612858494 0.9252014890696144 0.3548611090901055 1.0 0.8516666618162532 7 O75027,P08183 2 +Mtor signaling pathway 0.4416786967260308 0.9005171157343849 0.3678451209951809 1.0 0.8712121286727971 15 P31751,Q15418,P54646 3 +Proteasome 0.4075021025861411 0.8686867005664943 0.3850185176830853 1.0 0.8885042715763508 34 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +P53 signaling pathway 0.4419381746336189 0.8214782722027657 0.4113738953880195 1.0 0.9150947112222984 13 Q07812,P06493,P31350,P11802,P49815,Q7LG56,O96017 7 +Lysine degradation 0.3898674541768696 0.7926355552399995 0.4279901871713623 1.0 0.9150947112222984 21 Q9BWD1,O96028,P35610,P30837,P51648 5 +Apoptosis 0.418209428994291 0.7464580481052412 0.4553907648143098 1.0 0.9203412643840232 15 P31751,O94919,O95831 3 +Galactose metabolism 0.4190656750863455 0.7135432609747108 0.4755096532650786 1.0 0.9203412643840232 14 P06280,P17858,P52789 3 +N glycan biosynthesis 0.3891857145504028 0.6849577579094751 0.493370577331977 1.0 0.9348074096816406 18 Q9BT22,Q9BV10,Q86YN1 3 +Porphyrin and chlorophyll metabolism 0.4155489286241704 0.6576457808923976 0.5107657696527608 1.0 0.9478127684278036 13 P53701,Q96EY8,Q7KZN9,P30519 4 +Tryptophan metabolism 0.4036569635116029 0.6163489579652097 0.5376642331942563 1.0 0.9875465507649606 14 P35610,Q9BWD1,P51648 3 +Proximal tubule bicarbonate reclamation 0.4529679603851085 0.6071778750616854 0.5437328735556615 1.0 0.9886052246466572 8 Q9UBX3 1 +Hypertrophic cardiomyopathy hcm 0.439036462881133 0.5934549639572296 0.5528767142656128 1.0 0.995178085678103 9 P16615,P54646 2 +Ppar signaling pathway 0.3724841017660676 0.5682966619695806 0.5698335452300469 1.0 1.0 18 P23786,O14975,Q15067,O95864,O15254,Q9UKU0,P50416 7 +Butanoate metabolism 0.3651739544009084 0.5179587486029549 0.6044870511038907 1.0 1.0 18 P35610,Q9BWD1,P51648,Q9H9P8 4 +Glycosaminoglycan biosynthesis heparan sulfate 0.5914670641760247 0.4385326014105449 0.6610002425435608 1.0 1.0 3 Q7LGA3 1 +Adipocytokine signaling pathway 0.351311087836112 0.3261586228826234 0.7443043452136759 1.0 1.0 15 Q9UKU0,P11166,P31751,P50416,P54646 5 +Phosphatidylinositol signaling system 0.3757051316867504 0.3224882969254504 0.7470828022940279 1.0 1.0 10 Q10713,O95674,P42356,O14735,O96017 5 +Aldosterone regulated sodium reabsorption 0.4074726261916306 0.3106636840935092 0.7560563079413327 1.0 1.0 6 O14654,P05026,P05023 3 +Autoimmune thyroid disease 0.5301271113911346 0.2751143303472979 0.7832284022170344 1.0 1.0 3 P10321 1 +Graft versus host disease 0.5301271113911346 0.2751143303472979 0.7832284022170344 1.0 1.0 3 P10321 1 +Allograft rejection 0.5301271113911346 0.2751143303472979 0.7832284022170344 1.0 1.0 3 P10321 1 +Rig i like receptor signaling pathway 0.374727910161993 0.2426933259115409 0.8082429780610614 1.0 1.0 8 Q86UT6,Q7Z434 2 +Glycerolipid metabolism 0.3470482292313332 0.2271360591572114 0.8203179455590393 1.0 1.0 11 P51648,P06280 2 +Terpenoid backbone biosynthesis 0.334264053520505 0.1651445205330013 0.8688302317424663 1.0 1.0 11 Q86SQ9,Q9BWD1 2 +Nitrogen metabolism 0.3681592039800918 0.1016358616397057 0.9190457133551352 1.0 1.0 4 P08243,P00367,P32929 3 +Jak stat signaling pathway 0.3415852049357329 0.09882432204489 0.92127775681916 1.0 1.0 7 P31751,P62993 2 +Gap junction 0.2994867733740932 0.0825551814313796 0.934205239603225 1.0 1.0 17 Q13509,P68371,P04350,P06493,P63096,Q9BVA1,P62993 7 +Primary bile acid biosynthesis 0.3478396021137778 0.0325213147567549 0.9740563183007472 1.0 1.0 3 P51659,O75881 2 +Inositol phosphate metabolism 0.2994049589459112 0.0157772273369054 0.987412116129008 1.0 1.0 11 O14735,Q10713,Q02252 3 +Antigen processing and presentation 0.2901675495646432 0.0079414457513131 0.9936637096459836 1.0 1.0 15 Q03518,P27824,P61289 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e1b0a3cb6c3ed0779bb619b013420133b270e78e --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALYREF", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "APP", "APPL1", "APRT", "AQR", "ARF6", "ARFGAP1", "ARG2", "ARHGDIA", "ARHGEF2", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT2", "BIRC6", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BRK1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK6", "CDS2", "CETN2", "CFL1", "CFL2", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHST12", "CHST14", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTC", "CMPK1", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DARS", "DARS2", "DAXX", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOLPP1", "DPAGT1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBP", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EHD1", "EHD4", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "ETNK1", "EXO1", "EXOC3", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGCT", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "ILK", "IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "L2HGDH", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARS", "LARS2", "LDHA", "LDHB", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LYN", "LYPLA1", "LYPLA2", "M6PR", "MAD2L1", "MAN2A1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MFSD8", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPP5", "MPST", "MPV17", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYH10", "MYH9", "MYL6", "MYL6B", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NNT", "NPC1", "NPC2", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NTHL1", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC3", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS2", "PECR", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PI4KA", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIH", "PPIL1", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTDSS1", "PTDSS2", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB13", "RAB31", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RALB", "RAPGEF2", "RARS", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RDH11", "RDX", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RSL24D1", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCLY", "SCP2", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC33A1", "SLC38A1", "SLIT2", "SLK", "SLTM", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPCS2", "SPCS3", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TAF10", "TAF6L", "TALDO1", "TAOK2", "TAP1", "TAP2", "TARS", "TARS2", "TARSL2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TOLLIP", "TOMM40", "TOP3A", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "ULK3", "UMPS", "UNC45A", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USE1", "USP39", "USP8", "VAMP7", "VANGL1", "VANGL2", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VTA1", "WARS", "WASF2", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YKT6", "YOD1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "AIFM1", "AKT2", "ALDH1B1", "ALDH3A2", 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3.248015170624823e-05 0.0098773233595845 7.548910125606223e-05 3.9980443747095845e-05 1.6828407640817953e-08 +Metabolism of fat soluble vitamins 3 5 2.24510215985758 0.0247615749929244 1.6650485436893203 4.580097087378641 0.3536798037155611 0.3331745511018804 1.178052427490116 1.3130753903966457 1.3422038796699125 0.2910915635007025 0.2211054645003494 0.1330370821365251 0.2489059409173845 0.154226710893935 0.0498364179528963 +Processing of smdt1 4 13 2.1973265478385597 0.0279971329573527 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.0840307903449433 1.0 1.0 0.0557098434243155 0.0397387250697101 +Pink1 prkn mediated mitophagy 2 8 2.187376081838074 0.0287150807612917 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.013913202095476 0.0030581061915538 0.0005633424812776 0.0073447144383531 0.0078812527225172 +Synthesis of pa 3 10 2.1671476530370803 0.0302235973555857 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.0064716127922198 1.0 1.0 0.0215683584236732 0.0308662830144804 +Unwinding of dna 6 11 2.1377641478261564 0.0325358901954453 3.6359223300970873 9.509708737864075 0.4276038999200338 0.486594295939733 2.5415901439820705 1.0485324522950554 0.9385911632117738 0.312627671257055 0.050027591577048 1.0 1.0 0.2541534411772372 0.018020673376298 +Respiratory electron transport 14 60 2.0188431776010325 0.0435035217118879 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 5.498923441068985e-05 0.0014729216301342 0.0172354677097154 0.0030034349550393 9.953029542124808e-05 +O linked glycosylation 2 5 2.0059604774205995 0.0448604649065733 1.766990291262136 4.330097087378641 0.8603336668848929 0.3169450005244383 1.1529100664253755 1.1773621125091884 1.0771631098821022 0.279831511700265 0.0899509529230909 0.1583124314184509 0.2921659829416722 0.2064377407436189 0.2403376761227438 +O linked glycosylation of mucins 2 5 2.0059604774205995 0.0448604649065733 1.5946601941747574 3.79126213592233 0.8273892413522829 0.3233813801440507 0.9620319470039822 0.7664831800276773 1.0938082052075415 0.2789554131782936 0.0281770440971773 0.1026081339138497 0.1951188871774342 0.097689242801984 0.088385561156941 +Synthesis of pc 2 5 1.9777036926023364 0.0479621434596702 1.4975728155339805 5.177184466019417 0.9792901538510108 0.3349579960493364 1.1180313541111304 1.1575685242362048 0.9033750611806022 0.284045310792182 0.0281770440971773 1.0 0.1951188871774342 0.4160065505344545 0.088385561156941 +Transport of vitamins nucleosides and related molecules 4 7 1.9697583878598413 0.0488660677334062 3.2985436893203883 7.703883495145631 0.5884630304197642 0.3368828823659784 1.766928610360549 0.9135891377639136 1.2550983698791685 0.3076045725047946 0.0248830014547047 0.0981765691424607 0.1871299927573601 0.0133829456596615 0.017002584405276 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b479325476c634172d2504005065be2e60abb0e6 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 1394, + "title": "Average number of proteins per term", + "value": 19.227403156384504 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c65ca569bf8288cff94e7d5b0c1a316e11f5d12c --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..88833b8180a9e794c43f13739c0e39228dce8c3c --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,392 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.5160573163426742 3.4253741942072793 0.0006139531953426 0.5751901356003399 0.4387792156240129 81 P56589,P05067,Q13505,P62072,O60830,Q9Y5J6,P21796,O14975,Q9NS69,O96008,Q9Y584,Q2T9J0,P51648,O75431,Q8N4H5,O15228,P09601,Q10713,Q15067,O15254,Q99595,Q9Y5J9,Q9Y5Y5,O14925,P50402,P12236,P12235,P46379,Q9NR77,O14734,P33897,Q9Y512,O75381 33 +Sphingolipid metabolism 0.7634963717667285 3.4185638677097745 0.0006295254169641 0.5843180148728887 0.4387792156240129 26 P07602,P16278,Q9NZJ7,P04062,P27544,Q16739,O15269,P51648,O95470,P10619,P17900,Q96G23,Q13510,P06865,P06280 15 +Glycerophospholipid biosynthesis 0.6845698189454367 3.047061469258633 0.00231090447244 0.9602493367994452 0.5616630935835475 38 Q96N66,Q9NQZ5,Q9BVG9,Q8WUK0,P35790,Q9HBU6,Q8NF37,O95674,Q8NCC3,Q9NP80,Q9NUQ2,Q9NPH0,Q6P1A2,O14735,Q8IV08,Q9UG56,Q8N2A8 17 +Glycosphingolipid metabolism 0.7652268464713907 2.8916423671808986 0.0038323391578209 0.9952639116710776 0.5616630935835475 15 P07602,Q9NZJ7,P04062,Q16739,P10619,P17900,Q13510,P06865,P06280 9 +Mitochondrial calcium ion transport 0.7036697903362256 2.8042440861131537 0.0050434707784712 0.99913119114059 0.5616630935835475 18 Q9H4I9,Q10713,Q9Y277,Q8IYU8,P45880,P21796,Q9UJZ1 7 +Cholesterol biosynthesis 0.6754004158578877 2.72862040651991 0.0063599867094095 0.9998628087799528 0.5616630935835475 19 Q15125,Q9BWD1,P48449,Q16850,Q14534,Q9H2C2,Q15800,O75845,Q14739,Q15392 10 +Cristae formation 0.651710189933297 2.681123005214625 0.0073375539199851 0.9999652127986856 0.5616630935835475 21 P17152,P24539,Q9NVH1,Q6UXV4,Q13505,O75964,O75431,Q5XKP0,Q9Y512,P00846,O75947,Q9BUR5,P56385 13 +Slc mediated transmembrane transport 0.651439333983163 2.68054884447625 0.0073501536765496 0.999965822909951 0.5616630935835475 22 P12236,P30825,Q9UBX3,O00400,Q8TB61,Q70HW3,Q9H2J7,P12235,P11166,Q9Y6M7,P53985 11 +Mitochondrial protein import 0.6372484799690106 2.6799468627181713 0.0073633847962109 0.999966452086794 0.5616630935835475 36 Q10713,O14925,P12236,Q9Y5J6,Q9NS69,P12235,Q13505,O96008,Q9Y584,Q99595,Q9Y5J9,P62072,O60830,P21796,Q8N4H5 15 +Phospholipid metabolism 0.5820813970948979 2.6273896053355195 0.0086042755677067 0.9999941335416266 0.5616630935835475 54 Q96N66,Q9NQZ5,Q9BVG9,Q8WUK0,Q10713,P35790,Q9HBU6,Q8NF37,O95674,Q8NCC3,Q9NP80,Q9NUQ2,Q9NPH0,Q6P1A2,O14735,Q8IV08,Q9UG56,Q8N2A8 18 +Sphingolipid de novo biosynthesis 0.7565730253342604 2.559085089026535 0.0104948050358728 0.9999995899832504 0.5616630935835475 11 P27544,O15269,P51648,O95470,Q96G23 5 +Glycosaminoglycan metabolism 0.7195187195494921 2.558537953256726 0.0105113345496341 0.9999995994208852 0.5616630935835475 14 Q8TB61,Q8NCH0,Q7LGA3,P54802,O43505,P06865 6 +Stimuli sensing channels 0.7542134716590898 2.546704629509844 0.0108745433865822 0.9999997598831524 0.5616630935835475 11 P51798,Q4KMQ2,Q9NW15,Q9C0H2,Q12797,P27105,P51790 7 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4937456511467012 2.4447535095197086 0.0144951170276947 0.9999999985534284 0.5616630935835475 70 O43676,P03886,Q9P0S2,O14949,P00846,O75306,O95139,Q8N8Q8,Q86Y39,O75964,Q9NPL8,Q99643,P24539,Q9UDW1,P13073,O14548,Q9NX14,Q9Y6M9,Q9Y6N1,P56385,O75251,P22695,P21912,Q16134 24 +Transport of inorganic cations anions and amino acids oligopeptides 0.7339473936702474 2.439596635554052 0.0147036694550546 0.9999999989230132 0.5616630935835475 11 Q70HW3,Q9UBX3,Q9Y6M7,P30825 4 +Mitophagy 0.718127447636773 2.3550154879592897 0.0185219336877624 0.9999999999951964 0.5616630935835475 11 Q96HS1,Q15388,Q9NS69,O96008,O94826,Q8IWA4,P21796,Q8N4H5 8 +Transport of small molecules 0.4670699034889182 2.3308786060610567 0.0197597616829556 0.9999999999991728 0.5616630935835475 155 P56589,Q99797,P98194,P21281,P48556,O15118,Q4KMQ2,Q8TB61,Q70HW3,P30519,P35610,Q8IYU8,P28074,P21796,P05141,P27105,P51798,Q8N4V1,Q9H4I9,P49721,O00400,Q9NW15,Q9Y277,P05023,P60900,Q93050,Q9C0H2,Q12797,Q8WTV0,Q9Y6B6,Q9Y6M7,P45880,P20020,Q9Y487,P09601,P35613,Q9UBV2,Q10713,Q15904,P30825,Q9H2J7,P28070,Q13546,O00231,O75027,P20618,Q13438,P28072,P10644,P16615,P53985,Q9HD20,Q9H300,Q9UJZ1,P61289,P12236,Q9UBX3,Q9BUN8,P12235,P08183,P11166,Q99436,P33897,Q9UEY8,Q9BU23,O43242,P51790 67 +Metabolism of fat soluble vitamins 0.8682795790624196 2.2451021598575793 0.0247615749929244 0.9999999999999992 0.5815937446873295 5 P09455,Q8N0U8,Q6NUM9 3 +Processing of smdt1 0.667885981122087 2.1973265478385593 0.0279971329573527 1.0 0.6041978563888468 13 Q8IYU8,Q9H4I9,Q10713,Q9UJZ1 4 +Pink1 prkn mediated mitophagy 0.7632911776427658 2.187376081838074 0.0287150807612917 1.0 0.6041978563888468 8 P21796,Q9NS69 2 +Synthesis of pa 0.7096440703259205 2.1671476530370803 0.0302235973555857 1.0 0.6041978563888468 10 Q9NUQ2,Q9NPH0,Q8N2A8 3 +Unwinding of dna 0.6782109101202114 2.1377641478261564 0.0325358901954453 1.0 0.6041978563888468 11 Q14691,P25205,Q9Y248,O75419,P49736,Q14566 6 +Synthesis of pg 0.910447761194029 2.1205098117945216 0.033963074965182 1.0 0.6041978563888468 4 O95674,Q8IV08,Q8N2A8 3 +Respiratory electron transport 0.4934594075815492 2.0188431776010325 0.0435035217118879 1.0 0.6582682955764555 60 O75306,O43676,P03886,Q8N8Q8,Q86Y39,Q9UDW1,Q9P0S2,Q9NPL8,P13073,O14949,P22695,Q9Y6M9,Q16134,Q99643 14 +O linked glycosylation 0.811845449123434 2.0059604774205995 0.0448604649065733 1.0 0.6582682955764555 5 Q8N4A0,O43505 2 +O linked glycosylation of mucins 0.811845449123434 2.0059604774205995 0.0448604649065733 1.0 0.6582682955764555 5 Q8N4A0,O43505 2 +Synthesis of pc 0.8052708598653673 1.9777036926023364 0.0479621434596702 1.0 0.6892703915750543 5 Q9NQZ5,P35790 2 +Transport of vitamins nucleosides and related molecules 0.7438510000964877 1.9697583878598413 0.0488660677334062 1.0 0.6925882691711497 7 O00400,Q8TB61,P12236,P12235 4 +Chondroitin sulfate dermatan sulfate metabolism 0.7989733789101326 1.95056204254801 0.0511091662221872 1.0 0.6959582943061965 5 Q8NCH0,P06865 2 +The citric acid tca cycle and respiratory electron transport 0.3984122888882297 1.9375295209227523 0.0526806483623811 1.0 0.6959582943061965 103 O43676,P03886,Q9P0S2,O14949,P00846,P21796,O75306,Q13423,Q8N8Q8,Q86Y39,O75964,Q9NPL8,Q9H9P8,Q99643,Q9UDW1,P13073,Q9Y6M9,P22695,Q16134 19 +Synthesis of pe 0.8625621890547237 1.9296087301877296 0.0536553362895282 1.0 0.6959582943061965 4 Q9HBU6,P35790,Q9UG56 3 +Phase i functionalization of compounds 0.6151820863234523 1.8902149975348272 0.0587292116830473 1.0 0.7227378297477208 13 O43169,P16435,Q16850 3 +Metabolism of steroid hormones 0.7441458472046714 1.8588746740403963 0.0630449046702847 1.0 0.7227378297477208 6 O95772,Q53GQ0 2 +Class i peroxisomal membrane protein import 0.6073177870855189 1.8435024899354444 0.0652556785109488 1.0 0.7227378297477208 13 P56589,Q9Y5Y5,P51648,Q9NR77,P33897,O75381 6 +Diseases associated with glycosaminoglycan metabolism 0.7531277696318075 1.7508091726398542 0.0799787860637342 1.0 0.8142087378470342 5 Q8NCH0 1 +Synthesis of very long chain fatty acyl coas 0.6530279867219088 1.7471086798966295 0.0806184880508633 1.0 0.8142087378470342 9 Q9NZ01,Q53GQ0,Q9UKU0 3 +Metabolism of lipids 0.4477922927789585 1.7298097109468995 0.0836642788643462 1.0 0.8252401793943979 198 O95772,Q9UG56,Q15125,P48449,Q16850,Q9HBU6,Q8NF37,Q9P035,P04062,O95674,P35610,Q9NUQ2,P30536,P10619,Q9NPH0,O95470,Q6P1A2,Q96G23,Q15392,P06865,P50897,P06280,Q9BWD1,Q53GQ0,Q8WUK0,O75192,P23786,Q8NCC3,Q9UKU0,Q9NP80,O15269,P49748,P51648,Q9NZ01,Q15165,Q9UMR5,Q14739,O14735,Q13510,Q15800,Q9C0D9,Q9NQZ5,Q96N66,Q9BVG9,P07602,Q10713,P09960,Q14534,Q15067,O15254,O43772,O75845,P38435,Q9NZJ7,Q9H7Z7,Q9H2C2,Q14914,P54646,P35790,Q8IV08,Q8N2A8 61 +Activation of ampk downstream of nmdars 0.6645700467057967 1.7005729722469791 0.0890232029728408 1.0 0.8396756536043668 8 Q9BVA1,Q13509,P04350,P54646 4 +Disorders of transmembrane transporters 0.3926899125438666 1.6792562245913882 0.0931021184831102 1.0 0.8396756536043668 77 P48556,P28074,P49721,O00400,Q9BTX1,P60900,P35613,P28070,O00231,Q8NFH5,P20618,Q13438,P28072,P53985,Q8N1F7,P61289,Q9BUN8,Q9BW27,P11166,Q8NFH4,Q99436,P33897,O43242 23 +Peptide ligand binding receptors 0.6794497946903397 1.6615466989288057 0.0966036981056783 1.0 0.8396756536043668 7 P42892,P07602,Q9NZJ7 3 +Class a 1 rhodopsin like receptors 0.6794497946903397 1.6615466989288057 0.0966036981056783 1.0 0.8396756536043668 7 P42892,P07602,Q9NZJ7 3 +Sulfur amino acid metabolism 0.5842562148297784 1.652798282269753 0.0983719238064522 1.0 0.8396756536043668 12 Q9BV57,Q99757,Q13126,Q9UBX3 4 +Ras processing 0.6953167964242994 1.6332297329105463 0.1024206888249135 1.0 0.8396756536043668 6 O60725,O43924 2 +Formation of atp by chemiosmotic coupling 0.6069378705877582 1.6121904212162266 0.106920509044063 1.0 0.8396756536043668 10 O75964,P56385,P00846,P24539 4 +Ire1alpha activates chaperones 0.5002225556096245 1.6085177658437333 0.1077218284316599 1.0 0.8396756536043668 27 Q9NWM8,Q13217,P49748,O95070,O14653,O43731,P43307,O14773,Q9Y5M8,Q9HCU5,O76024 11 +Organelle biogenesis and maintenance 0.3676937677868417 1.6080664854827509 0.1078206183609624 1.0 0.8396756536043668 95 O75935,Q9NVH1,Q13505,Q86X55,P00846,Q15154,A6NIH7,Q13509,P17152,O43805,Q9Y496,O75964,O75431,Q10713,P24539,Q6UXV4,P41208,Q9BUR5,P56385,Q96CS2,O94927,Q5XKP0,Q9H6D7,P54646,Q9Y512,O75947,O43924,O95684 28 +Intra golgi traffic 0.5247883406832236 1.5721534936107369 0.1159149580045968 1.0 0.8810233814756885 17 O43752,Q96JB2,O95249,O00461,Q8TBA6 5 +Carboxyterminal post translational modifications of tubulin 0.6594696300551497 1.5641310431841084 0.1177867970377237 1.0 0.8827677154332632 7 Q14166,Q13509,P04350,Q9BVA1 4 +Visual phototransduction 0.6356705120989763 1.553528459332584 0.1202969356594472 1.0 0.8858170336020169 8 P49356,P09455 2 +Keratan sulfate keratin metabolism 0.6716330246936691 1.5222205983375552 0.1279538155518911 1.0 0.8858170336020169 6 O43505,P16278,P06865 3 +Diseases of glycosylation 0.4859127711084664 1.514174626915498 0.1299815551890661 1.0 0.8925826991800899 22 Q86SQ9,Q8NCH0,P10619,O43505,Q9BV10,P06865 6 +Response to elevated platelet cytosolic ca2 0.4857993808875524 1.5036203879039831 0.1326791385226022 1.0 0.9022181419536954 33 Q92520,Q08380,P05067,P07602,Q96JJ7,Q9NZJ7,Q6UXV4,Q8NBX0,Q8NBM8,O43852,O94919,Q9NUQ9,Q9NTK5 13 +Gpcr ligand binding 0.6042556358880544 1.488108375918394 0.1367223149254939 1.0 0.9075757476482788 9 P42892,P07602,Q9NZJ7 3 +G1 s specific transcription 0.5789706968702036 1.4558125032527904 0.1454444583963159 1.0 0.9253742526201806 10 P00374,Q9Y619,O75419 3 +Pre notch processing in golgi 0.7427731654927416 1.438621043939132 0.1502579206982277 1.0 0.9253742526201806 4 Q15363,P16615 2 +Gap junction assembly 0.6519020745272913 1.4290754982052405 0.1529825349370297 1.0 0.9253742526201806 6 Q9BVA1,P04350,Q13509 3 +Transport of connexons to the plasma membrane 0.6519020745272913 1.4290754982052405 0.1529825349370297 1.0 0.9253742526201806 6 Q9BVA1,P04350,Q13509 3 +Constitutive signaling by akt1 e17k in cancer 0.6472340281821443 1.406961476545391 0.1594388123424299 1.0 0.9253742526201806 6 P49840,Q96B36,P49815,P31751 4 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.5693380362989031 1.4015154794493432 0.161059981932415 1.0 0.9253742526201806 10 Q9BU89,O60725 2 +Signaling by fgfr1 in disease 0.5848891147082681 1.3837680406716948 0.1664294919049549 1.0 0.9253742526201806 9 Q16630,O95684,P62993 3 +Fgfr1 mutant receptor activation 0.5848891147082681 1.3837680406716948 0.1664294919049549 1.0 0.9253742526201806 9 Q16630,O95684,P62993 3 +Akt phosphorylates targets in the cytosol 0.6650077760497694 1.3577533862058788 0.1745419504961494 1.0 0.9253742526201806 5 P49840,P49815,Q96B36,P31751 4 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4825494552013299 1.3492871660517716 0.1772447462711617 1.0 0.9253742526201806 18 Q07065,P05067,Q02818,Q9BTY2,Q13217,O43852,O76024 7 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7210820895522352 1.3482772481578915 0.1775692270412991 1.0 0.9253742526201806 4 P05141,P12236,P12235 3 +Amino acid transport across the plasma membrane 0.6597485705015759 1.3340183527156246 0.1821978418939509 1.0 0.9253742526201806 5 Q9H2J7,P30825 2 +Cargo concentration in the er 0.5061847253539826 1.3248827695976864 0.1852100365658755 1.0 0.9253742526201806 15 Q5JRA6,Q15363,P49755,O14653,Q9HCU5,Q9Y6B6,Q96PC5 7 +Signaling by cytosolic fgfr1 fusion mutants 0.6108191567608101 1.3240357066188804 0.1854911863537451 1.0 0.9253742526201806 7 Q16630,O95684,P62993 3 +Metabolism of steroids 0.4498707910249858 1.3146165853983092 0.1886387932257807 1.0 0.9253742526201806 47 O95772,Q15125,P48449,Q16850,Q9BWD1,Q53GQ0,P38435,Q14534,Q9H2C2,P04062,P30536,Q15800,O75845,Q14739,Q15392 15 +Fatty acyl coa biosynthesis 0.4949427229410803 1.307397495674653 0.1910777474378071 1.0 0.9253742526201806 16 Q53GQ0,Q9UKU0,Q9NZ01,Q9UMR5,P50897 5 +Acyl chain remodelling of pc 0.7109498672147556 1.306010218584248 0.191549082580277 1.0 0.9253742526201806 4 Q8NF37,Q9NP80 2 +Plasma lipoprotein clearance 0.5132142038937679 1.2685490726369115 0.2046019379047505 1.0 0.9253742526201806 13 Q8WTV0,O15118 2 +Cytochrome p450 arranged by substrate type 0.6998426859042576 1.2596531461834768 0.2077945144388073 1.0 0.9253742526201806 4 Q16850 1 +Signaling by pdgfr in disease 0.6423017107309367 1.2551580722977886 0.2094213826251612 1.0 0.9253742526201806 5 P40763,O43815,P42224,P62993 4 +Pregnenolone biosynthesis 0.6971149108504446 1.2482673190742295 0.2119331781168525 1.0 0.9253742526201806 4 O95772 1 +Er quality control compartment erqc 0.695060258501655 1.2396912918113177 0.2150895993107799 1.0 0.9253742526201806 4 Q13438,O60858 2 +Heparan sulfate heparin hs gag metabolism 0.692735876545097 1.2299898166330063 0.218700918249221 1.0 0.9253742526201806 4 P54802,Q7LGA3 2 +Selective autophagy 0.4518734371847095 1.229788891099886 0.218776169241823 1.0 0.9253742526201806 32 Q96HS1,P04350,P50542,Q9NS69,O96008,Q15388,O94826,Q8IWA4,P54646,Q9BVA1,P08670,P21796,Q8N4H5,Q13509 14 +Synthesis secretion and deacylation of ghrelin 0.8172210133664786 1.2247158975505146 0.220682282179863 1.0 0.9253742526201806 3 Q15005,P67812 2 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8172210133664786 1.2247158975505146 0.220682282179863 1.0 0.9253742526201806 3 Q15005,P67812 2 +Assembly and cell surface presentation of nmda receptors 0.5101592469388824 1.205721040170476 0.2279250695573393 1.0 0.9455376149136044 12 P68371,P04350,Q9BVA1,Q14168,P07196,Q13509 6 +Metabolism of folate and pterines 0.5512008684338333 1.2007413574404515 0.2298515459505314 1.0 0.9455376149136044 9 Q9H2D1 1 +Signaling by ptk6 0.5083371081197381 1.1945707557790426 0.232254780763816 1.0 0.9455376149136044 12 P23246,Q8IZL8,P46108,P40763,Q07666,Q96JJ3,P18031 7 +Vitamin c ascorbate metabolism 0.8069827144775192 1.1864132444650113 0.2354591438308013 1.0 0.9455376149136044 3 P78417 1 +Cargo trafficking to the periciliary membrane 0.4572598483099821 1.1698958376042603 0.2420428891656567 1.0 0.9503410917066902 18 Q10713,A6NIH7 2 +Keratan sulfate degradation 0.677725091004457 1.1673643740516688 0.2430632519119018 1.0 0.9503410917066902 4 P16278,P06865 2 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6224322562289704 1.16522162088958 0.2439292960229326 1.0 0.9503410917066902 5 O14654,P31751 2 +Peroxisomal lipid metabolism 0.4893869427374905 1.164767002559657 0.244113319070605 1.0 0.9503410917066902 14 O14975,Q15067,O15254,P51648,O14734,P33897 6 +Translation of sars cov 1 structural proteins 0.5748086051705277 1.144508209323705 0.2524129353096833 1.0 0.9503410917066902 7 Q10472 1 +Alpha oxidation of phytanate 0.6176652751275027 1.143642619917255 0.2527718788294146 1.0 0.9503410917066902 5 O14975,P51648 2 +Vitamin d calciferol metabolism 0.9288377874456146 1.142283908289018 0.2533360278045471 1.0 0.9503410917066902 2 P04062 1 +Abc transporters in lipid homeostasis 0.6644900497512393 1.1122252151897436 0.2660413289656846 1.0 0.9533717546996516 4 P56589,P33897,P28288 3 +Cytoprotection by hmox1 0.385677792835684 1.1045432393935548 0.2693575576234159 1.0 0.9556171347918494 66 P48556,P30519,Q9P0S2,P28074,Q8TCT9,Q86X55,P49721,Q8N8Q8,P67870,P09669,P60900,P40763,Q9UL46,P20674,P09601,P28070,O00231,P20618,P28072,P13073,O14548,P00403,Q9Y6N1,P61289,Q99436,O43242 26 +Initiation of nuclear envelope ne reformation 0.4382461515508593 1.0979089554915642 0.2722442470350119 1.0 0.9607809629539408 19 P50402,Q86XL3,P42167,Q8IXJ6,Q14739 5 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.6599367794449349 1.0932825068755256 0.2742697810139973 1.0 0.9624327194187536 4 Q15005,P67812 2 +Incretin synthesis secretion and inactivation 0.6599367794449349 1.0932825068755256 0.2742697810139973 1.0 0.9624327194187536 4 Q15005,P67812 2 +Plasma lipoprotein assembly remodeling and clearance 0.454725853070845 1.0911488005939114 0.2752074124549781 1.0 0.9624327194187536 17 Q9BU23,Q8WTV0,O15118 3 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.5613628008243041 1.0773241173113584 0.2813354915167263 1.0 0.965431911448156 7 Q16850 1 +Synthesis of leukotrienes lt and eoxins ex 0.7762952600786956 1.0721164493996698 0.2836677313709463 1.0 0.9659676806297344 3 Q14914 1 +Rsk activation 0.6546080823444569 1.0711363157017673 0.2841081413616866 1.0 0.9659676806297344 4 Q15418 1 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7751434344529573 1.0678460370578893 0.2855899676111568 1.0 0.9662922690532832 3 Q8NB78 1 +Endosomal vacuolar pathway 0.7721479639415525 1.056748372754882 0.2906264419123063 1.0 0.9690272299900672 3 P10321,Q9UIQ6 2 +Platelet calcium homeostasis 0.7717173001714175 1.055153828196956 0.2913549769550423 1.0 0.9690272299900672 3 P16615 1 +Reduction of cytosolic ca levels 0.7717173001714175 1.055153828196956 0.2913549769550423 1.0 0.9690272299900672 3 P16615 1 +Methionine salvage pathway 0.7709693207553601 1.052385015428651 0.2926229407595651 1.0 0.9690272299900672 3 Q13126 1 +Nr1h2 and nr1h3 mediated signaling 0.5970870670773736 1.050582535602887 0.2934503655978833 1.0 0.9690272299900672 5 Q8NB78,Q9HCE1 2 +Rhod gtpase cycle 0.4275436478830926 1.0444460706190632 0.2962790579350978 1.0 0.9690272299900672 27 Q9H0H5,P50402,P42167,O15173,Q68EM7,P42166,Q9Y6M7,Q14739,Q8TAA9 9 +Rnd2 gtpase cycle 0.4462261595916329 1.0320861657857063 0.3020317540250636 1.0 0.9690272299900672 17 Q9Y2I1,Q9ULK5,P51648,Q8TAA9 4 +Intra golgi and retrograde golgi to er traffic 0.329708990039545 1.0304277063049163 0.3028092726878977 1.0 0.9690272299900672 99 Q9H0H5,O75935,Q15363,O15260,O14653,Q10472,Q5VZE5,O43264,P24390,O60499,Q13509,O43752,O95249,O43731,Q9UJW0,Q9Y3B3,Q9P2W9,O00461,Q8TBA6,Q96JB2,Q8N2H4 21 +Signaling by egfr in cancer 0.6438309429025337 1.02643619540951 0.3046860242252367 1.0 0.9690272299900672 4 Q16543 1 +Constitutive signaling by ligand responsive egfr cancer variants 0.6438309429025337 1.02643619540951 0.3046860242252367 1.0 0.9690272299900672 4 Q16543 1 +Constitutive signaling by egfrviii 0.6438309429025337 1.02643619540951 0.3046860242252367 1.0 0.9690272299900672 4 Q16543 1 +Beta oxidation of pristanoyl coa 0.6409318849354074 1.0144358687232085 0.3103748162097379 1.0 0.9696281206678932 4 O15254 1 +Gastrin creb signalling pathway via pkc and mapk 0.587444137766932 1.00707643479057 0.3138980445642614 1.0 0.9696281206678932 5 Q15418,P51812 2 +Unfolded protein response upr 0.4195399031064064 1.0027649650720472 0.3159742765309472 1.0 0.9696281206678932 43 Q9NWM8,Q9NQT5,Q92945,Q13217,P49748,O95070,O14653,O43731,P43307,O14773,Q9Y5M8,Q9HCU5,O76024,Q96B26 14 +Asymmetric localization of pcp proteins 0.4229852740834114 1.0011639410962572 0.3167475563341089 1.0 0.9696281206678932 37 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,Q9ULK5,P61289 10 +Biosynthesis of specialized proresolving mediators spms 0.7547928550770143 0.9927087579824264 0.320851905674554 1.0 0.9696281206678932 3 Q14914 1 +Mucopolysaccharidoses 0.7538078955548577 0.989088954421246 0.3226196213343062 1.0 0.9709063164864284 3 P54802,P16278 2 +Mitochondrial biogenesis 0.419738137424665 0.97006665384755 0.332013269237188 1.0 0.9789328787735746 35 P56385,P17152,P24539,Q9NVH1,Q6UXV4,Q13505,O75964,O75431,Q5XKP0,Q86X55,Q9Y512,P00846,O75947,Q9BUR5,P54646 15 +Defects in cobalamin b12 metabolism 0.6293920061966835 0.9667896261975408 0.3336492114178013 1.0 0.9789328787735746 4 Q96EY8 1 +Acyl chain remodelling of pe 0.8735239279055214 0.9417364946937832 0.3463275656102742 1.0 0.995296560939002 2 Q9NP80 1 +Hyaluronan metabolism 0.7352523572794607 0.9212445197170528 0.3569227796598797 1.0 0.995296560939002 3 P06865 1 +Hyaluronan uptake and degradation 0.7352523572794607 0.9212445197170528 0.3569227796598797 1.0 0.995296560939002 3 P06865 1 +Pi3k akt signaling in cancer 0.4690452855095451 0.919251518766142 0.3579640296780053 1.0 0.995296560939002 11 O43815,P49840,Q96B36,P49815,P31751,P62993 6 +Activation of nmda receptors and postsynaptic events 0.4085673459422612 0.912309225637508 0.3616059591656397 1.0 0.995296560939002 24 P68371,P04350,P51812,Q9BVA1,Q14168,P52292,P10644,P54646,P07196,Q15418,Q13509 11 +Degradation of cysteine and homocysteine 0.5282455757458933 0.9121913695153976 0.3616679863608256 1.0 0.995296560939002 7 Q99757,Q9UBX3 2 +Cellular response to chemical stress 0.3322890856695585 0.9068877128428356 0.3644661794324311 1.0 0.995296560939002 77 P48556,P30519,Q9P0S2,P28074,Q8TCT9,Q86X55,Q8TED1,P49721,Q8N8Q8,P67870,P09669,P60900,P40763,Q9UL46,Q99757,P00390,P09601,P28070,O00231,P20618,P13073,P28072,O14548,Q9Y6N1,P61289,Q99436,O43242 27 +Signaling by erbb2 in cancer 0.7281374334083135 0.895427206095805 0.3705587626451521 1.0 0.995296560939002 3 Q16543 1 +Signaling by erbb2 ecd mutants 0.7281374334083135 0.895427206095805 0.3705587626451521 1.0 0.995296560939002 3 Q16543 1 +Constitutive signaling by overexpressed erbb2 0.7281374334083135 0.895427206095805 0.3705587626451521 1.0 0.995296560939002 3 Q16543 1 +Complex i biogenesis 0.4070248108894022 0.8666795476628397 0.386117614597844 1.0 1.0 32 O75306,O43676,P03886,Q86Y39,Q9NPL8 5 +Piwi interacting rna pirna biogenesis 0.45938809031179 0.8613510353845252 0.3890447352065593 1.0 1.0 11 Q8N2A8 1 +Mitotic g1 phase and g1 s transition 0.3388571258387524 0.8548438330116775 0.3926376083455685 1.0 1.0 74 Q9NRF9,P25205,P49721,P48556,P61289,P28070,O00231,Q9Y619,O75419,P31350,P60900,P20618,P28074,P31751,P28072,Q99436,P00374 17 +Signal regulatory protein family interactions 0.715063222877714 0.8483181967883953 0.3962607862004978 1.0 1.0 3 Q08722 1 +Rac2 gtpase cycle 0.40485637377857 0.8469218819927324 0.3970386648349198 1.0 1.0 35 Q9H0H5,Q86XL3,P50402,P42167,O15173,Q68EM7,Q13505,Q9Y512,Q14739,Q8TAA9 10 +Iron uptake and transport 0.4117918040225375 0.8452344423659142 0.3979799556405696 1.0 1.0 18 Q93050,P30519,Q9Y487 3 +Rnd1 gtpase cycle 0.4389412834681746 0.8404060218242665 0.400680773932947 1.0 1.0 14 Q9ULK5,P51648,Q9BXS4 3 +Regulation of runx3 expression and activity 0.4040555338520573 0.8403837502637971 0.4006932571788111 1.0 1.0 34 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Methylation 0.5252752904444771 0.8264646543163823 0.4085405604305148 1.0 1.0 6 P78417 1 +Linoleic acid la metabolism 0.7082267912427336 0.8238748901757206 0.4100106492021753 1.0 1.0 3 O95864 1 +Slc transporter disorders 0.4019975894507304 0.8232943187469833 0.4103406436016319 1.0 1.0 35 P35613,Q12769,O00400,Q9BW27,Q9BTX1,Q8NFH5,P11166,P08195,Q8NFH4,P53985,Q8N1F7 11 +Abc transporter disorders 0.3988798976078065 0.8154520567894137 0.4148135969847586 1.0 1.0 42 P49721,P48556,Q9BUN8,P28070,O00231,P60900,P20618,P28074,Q13438,P28072,Q99436,P33897,P61289 13 +Regulation of pten stability and activity 0.4001210568805962 0.8137550373384863 0.4157852977133531 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P31751,P28072,Q99436,P61289 11 +Irs mediated signalling 0.5890369457018169 0.8023509930390187 0.4223499529082801 1.0 1.0 4 P31751 1 +Recruitment of numa to mitotic centrosomes 0.3991358429104387 0.8010514052374365 0.4231018869678236 1.0 1.0 37 Q96CS2,O94927,O75935,P68371,O43805,P04350,Q9BSJ2,P07437,P06493,P41208,Q7Z460,O95684,Q9H6D7,Q9BVA1,P61163,Q15154,Q15691,Q13509 18 +Mitotic g2 g2 m phases 0.3049748241955084 0.7987868975316856 0.4244139892321943 1.0 1.0 88 Q96CS2,O94927,P49721,P61289,O75935,O43805,P48556,P28070,O00231,P41208,P20618,P28074,P28072,O95684,Q9H6D7,Q99436,Q15154,Q13509 18 +Degradation of axin 0.3989230834532781 0.7979039930914588 0.4249262059864382 1.0 1.0 35 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Cross presentation of soluble exogenous antigens endosomes 0.3989230834532781 0.7979039930914588 0.4249262059864382 1.0 1.0 35 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Synthesis of dolichyl phosphate 0.698613588972302 0.789748448981424 0.4296746906201671 1.0 1.0 3 Q86YN1 1 +Aurka activation by tpx2 0.3971803699947761 0.7894730852104993 0.4298355545886048 1.0 1.0 31 Q96CS2,O94927,O75935,P68371,O43805,P04350,P07437,P06493,P41208,Q7Z460,O95684,Q9H6D7,P61163,Q15154,Q15691 15 +Ra biosynthesis pathway 0.6968263688447969 0.7834375241963987 0.4333702279913798 1.0 1.0 3 Q8NBN7 1 +Post translational modification synthesis of gpi anchored proteins 0.4863437888459201 0.7770846420384159 0.4371088343241305 1.0 1.0 8 Q9Y2B2,O43292,Q9H490 3 +Recruitment of mitotic centrosome proteins and complexes 0.3958645493236653 0.7763551259169714 0.4375393325559127 1.0 1.0 32 Q96CS2,O94927,O75935,P68371,O43805,P04350,Q9BSJ2,P07437,P06493,P41208,Q7Z460,O95684,Q9H6D7,P61163,Q15154,Q15691 16 +Flt3 signaling in disease 0.5121344119477322 0.7649245426713478 0.4443164785157072 1.0 1.0 6 Q01082,Q06124,Q9UBW7,P22681,P62993 5 +Proton coupled monocarboxylate transport 0.8206960845245513 0.7576787059547999 0.448643349757984 1.0 1.0 2 P53985 1 +Ros and rns production in phagocytes 0.4679255111141036 0.7470479495628748 0.4550346176165321 1.0 1.0 9 Q93050,Q9Y487 2 +Flt3 signaling 0.5289089275420761 0.7465623678608355 0.4553277713703294 1.0 1.0 5 P31751 1 +Anchoring of the basal body to the plasma membrane 0.3918657612138118 0.7440795128588571 0.4568283728131594 1.0 1.0 32 Q96CS2,O94927,O75935,P68371,O43805,P04350,P07437,P06493,P41208,Q7Z460,O95684,Q9H6D7,P61163,Q15154,Q15691 15 +Wax and plasmalogen biosynthesis 0.5744093436040834 0.7439311918244412 0.4569181037624621 1.0 1.0 4 Q6IAN0,O15228 2 +Negative regulation of notch4 signaling 0.3920262589009036 0.742919415268182 0.4575304703292584 1.0 1.0 38 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Degradation of dvl 0.3920505735350277 0.7411660702328835 0.4585927532445732 1.0 1.0 36 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Regulation of ras by gaps 0.3920505735350277 0.7411660702328835 0.4585927532445732 1.0 1.0 36 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Creb phosphorylation 0.6844288255529285 0.7399744008684649 0.4593155274810665 1.0 1.0 3 Q15418 1 +Defective cftr causes cystic fibrosis 0.3905539018337902 0.7387358558351738 0.4600674085999729 1.0 1.0 41 P49721,P48556,Q9BUN8,P28070,O00231,P60900,P20618,P28074,Q13438,P28072,Q99436,P61289 12 +Depolymerisation of the nuclear lamina 0.4660902705228012 0.7371804744749354 0.4610126057375936 1.0 1.0 9 P42166,P50402,P06493,P42167 4 +Ptk6 regulates proteins involved in rna processing 0.8104412678682437 0.7231531903388572 0.4695857736709721 1.0 1.0 2 Q07666 1 +Hs gag degradation 0.8095090118085606 0.7200374876052511 0.4715019146569412 1.0 1.0 2 P54802 1 +Abc family proteins mediated transport 0.3796512651308888 0.718415457479214 0.4725011587067609 1.0 1.0 51 P56589,P49721,P48556,Q9BUN8,P28070,O00231,P08183,P60900,O75027,P28074,P20618,Q13438,P28072,Q99436,P33897,P61289 16 +Maturation of sars cov 2 nucleoprotein 0.5006639883654854 0.7116880407629174 0.4766579749194775 1.0 1.0 6 P49840,P48729,P78362 3 +Signaling by insulin receptor 0.4062174253177366 0.709060857930975 0.4782867116155977 1.0 1.0 16 Q93050,P31751,Q9Y487 3 +Cilium assembly 0.3637530381109378 0.708193386710195 0.4788251724531458 1.0 1.0 60 Q96CS2,Q10713,O94927,O75935,O43805,P41208,O95684,Q9H6D7,O43924,Q15154,A6NIH7,Q13509 12 +Interaction between l1 and ankyrins 0.6729872552067191 0.7003924409171852 0.4836822556724751 1.0 1.0 3 Q01082,Q13813 2 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4574076221056732 0.6906732350328855 0.489770912886593 1.0 1.0 9 P07196,Q15418,P51812 3 +Cellular response to hypoxia 0.3856012038907402 0.6905858079842445 0.4898258686629191 1.0 1.0 39 P49721,P48556,P28070,O00231,P20618,P28074,Q9Y241,P28072,Q99436,P61289 10 +Hedgehog ligand biogenesis 0.3845628695647974 0.6818117435816502 0.4953579975556443 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,Q13438,P28072,Q99436,P61289 11 +Mtor signalling 0.4015577032103715 0.6779966733865851 0.49777380244529 1.0 1.0 16 P62942,P31751 2 +Post chaperonin tubulin folding pathway 0.4282337417576422 0.6761008078356638 0.4989766438041423 1.0 1.0 11 P36404,P68371,P04350,Q9BVA1,Q13509 5 +Antigen processing cross presentation 0.3771154304643168 0.6637928760497397 0.5068228858594446 1.0 1.0 48 Q9UIQ6,P49721,P48556,Q03518,P28070,O00231,P20618,P28074,P28072,Q99436,P10321,P61289 12 +Stabilization of p53 0.3826613098227062 0.6635650352885127 0.5069687419912547 1.0 1.0 37 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Cell surface interactions at the vascular wall 0.4109289723665297 0.6620570835569511 0.5079346386826744 1.0 1.0 14 P35613,Q92896,Q08722,P05026,P14174,P08195,P53985,P62993 8 +Cyclin a cdk2 associated events at s phase entry 0.3812189688613072 0.6585256226192026 0.5102004381616476 1.0 1.0 41 P49721,P48556,P28070,O00231,P20618,P28074,P31751,P28072,Q99436,P61289 10 +Ion channel transport 0.3802056859785619 0.6577231684684481 0.5107160320886535 1.0 1.0 30 P51798,P98194,P21281,Q15904,Q4KMQ2,Q9NW15,P05023,P51790,Q93050,Q9C0H2,Q12797,P16615,Q9HD20,P27105,P20020,Q9Y487 16 +Interleukin 6 family signaling 0.5522388059701427 0.6570682601043945 0.5111370264323813 1.0 1.0 4 P22681,P40763,P42224 3 +Interleukin 6 signaling 0.5522388059701427 0.6570682601043945 0.5111370264323813 1.0 1.0 4 P22681,P40763,P42224 3 +Downstream signaling events of b cell receptor bcr 0.3811944131516734 0.6554774606378255 0.5121603935155934 1.0 1.0 40 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P62942,P61289 10 +Cdt1 association with the cdc6 orc origin complex 0.3813623959535716 0.6527813284344344 0.5138972625214295 1.0 1.0 37 P49721,P48556,P28070,O00231,Q9Y619,P20618,P28074,P28072,Q99436,P61289 10 +Signaling by notch4 0.3802358702716802 0.6473359408680245 0.5174145452941947 1.0 1.0 40 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Interleukin 35 signalling 0.6573128859677553 0.6470993163257233 0.5175676677539587 1.0 1.0 3 P27824 1 +Interleukin 27 signaling 0.6573128859677553 0.6470993163257233 0.5175676677539587 1.0 1.0 3 P27824 1 +Hedgehog off state 0.3712225070036035 0.6393071969967786 0.5226231074441579 1.0 1.0 51 P49721,P48556,P61289,P04350,P28070,Q9Y496,O00231,O43242,P60900,P20618,Q96J02,P28074,P28072,P10644,Q99436,Q9BVA1,P48729,Q13509 18 +Attachment of gpi anchor to upar 0.5025688955001625 0.6330316751141973 0.5267129584681729 1.0 1.0 5 O43292,Q9H490 2 +Interleukin 2 family signaling 0.6506061548025994 0.6246595375534286 0.5321945348413841 1.0 1.0 3 P40763,P62993 2 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6506061548025994 0.6246595375534286 0.5321945348413841 1.0 1.0 3 P40763,P62993 2 +Ddx58 ifih1 mediated induction of interferon alpha beta 0.4093317418657662 0.6195164597977192 0.5355761820077454 1.0 1.0 13 Q86UT6,P05067,Q7Z434,Q13546,O94826 5 +Bmal1 clock npas2 activates circadian gene expression 0.6485280691099895 0.6177538384126987 0.5367376166108992 1.0 1.0 3 P43490 1 +Acyl chain remodelling of pg 0.7762585456805272 0.6117134733216674 0.5407273460682627 1.0 1.0 2 Q8NF37 1 +Basigin interactions 0.4787563452621055 0.6116361056999061 0.5407785442486812 1.0 1.0 6 P53985,P35613 2 +Downregulation of erbb2 signaling 0.4757391533931021 0.5980577790586308 0.5498013807808722 1.0 1.0 6 P31751 1 +Transcriptional regulation by runx2 0.367112608106562 0.5906222080952052 0.5547735813592833 1.0 1.0 50 P49721,P48556,P28070,O00231,Q96PK6,P20618,P28074,P31751,P28072,Q99436,P61289 11 +The role of gtse1 in g2 m progression after g2 checkpoint 0.3666160761621427 0.576794083542627 0.5640785667880583 1.0 1.0 49 P49721,P48556,P61289,P28070,O00231,P20618,P28074,P28072,Q99436,Q13509 10 +Transcriptional regulation by runx3 0.3713489113982223 0.5707561508187117 0.568164950393963 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4864216561585934 0.5652634667115033 0.5718945738144279 1.0 1.0 5 O14975 1 +Insulin receptor recycling 0.421744294794726 0.5646089036294375 0.572339807887742 1.0 1.0 10 Q93050,Q9Y487 2 +Orc1 removal from chromatin 0.3659161285810791 0.5621630718618041 0.5740049189877827 1.0 1.0 48 P25205,P49721,P48556,P28070,O00231,Q9Y619,P60900,P20618,P28074,P28072,Q99436,P61289 12 +Signaling by the b cell receptor bcr 0.3691742057403088 0.5620283399474344 0.5740967105005779 1.0 1.0 43 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P62942,P61289 10 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3577133134696349 0.5619384296496122 0.5741579693590553 1.0 1.0 20 P10619,Q9BV10,Q86YN1 3 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.4436947217602335 0.5609959797321417 0.5748002778417913 1.0 1.0 8 O14734,Q15067,O95864 3 +The phototransduction cascade 0.4849815212206422 0.5593003214434047 0.5759567760185962 1.0 1.0 5 P49356 1 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.4075527432581278 0.5555444072477669 0.5785223445726024 1.0 1.0 11 P09601,P50402,P05067,P46379,P51648 5 +Tysnd1 cleaves peroxisomal proteins 0.4646535199902554 0.5486636651617947 0.5832362858625895 1.0 1.0 6 Q2T9J0 1 +Activated notch1 transmits signal to the nucleus 0.7557489123679348 0.547990337556417 0.5836985374843935 1.0 1.0 2 Q92542 1 +Copi dependent golgi to er retrograde traffic 0.3612213380849344 0.546037564244584 0.5850401160815242 1.0 1.0 51 Q9Y3B3,Q9H0H5,Q9Y496,Q15363,O15260,O43264,O43731,Q9P2W9,P24390,Q13509 10 +Activation of smo 0.7538844002486061 0.5423293023215852 0.5875916729818638 1.0 1.0 2 Q9Y496 1 +Synthesis of pi 0.7532628962088209 0.5404474134010804 0.5888885173227594 1.0 1.0 2 O14735 1 +Uch proteinases 0.3669432537677919 0.5394997172744163 0.5895420920034682 1.0 1.0 42 Q8NB78,P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 11 +Transferrin endocytosis and recycling 0.404707487260998 0.5391842653802047 0.5897597162526877 1.0 1.0 11 Q93050,Q9Y487 2 +Regulation of runx2 expression and activity 0.3669341903745118 0.5368766822519703 0.5913527987330152 1.0 1.0 41 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Synthesis of dna 0.2826448450538046 0.532798875032761 0.5941728126657644 1.0 1.0 83 Q9NRF9,Q14691,P25205,P49721,P48556,P28070,O00231,Q9Y619,O75419,Q9Y248,P60900,P20618,P40938,P49736,P28074,P28072,Q99436,P61289 18 +Metabolism of porphyrins 0.4263337650678803 0.5274451013960713 0.5978845304809552 1.0 1.0 9 P09601,Q7KZN9,P22830,P30519 4 +Signaling by kit in disease 0.5167757970104496 0.5236916784254999 0.6004930044706056 1.0 1.0 4 P40763,P62993 2 +Interleukin 15 signaling 0.7458048477315153 0.5180685308791912 0.6044104555770318 1.0 1.0 2 P62993 1 +G1 s dna damage checkpoints 0.3641289282297378 0.510690835115243 0.6095675592236167 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Pcp ce pathway 0.3614024907862793 0.5085251098636978 0.6110851342058083 1.0 1.0 46 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,Q9ULK5,P61289 10 +Tp53 regulates metabolic genes 0.363696593376651 0.5079825111015007 0.6114656081850636 1.0 1.0 40 Q8N8Q8,Q9P0S2,P13073,P31751,P54646,Q9Y6N1 6 +Diseases associated with n glycosylation of proteins 0.4328805444846916 0.507894357379271 0.6115274320871391 1.0 1.0 8 Q9BV10,Q9BT22 2 +Signaling by flt3 fusion proteins 0.5118159203980026 0.5057113135870239 0.6130593248652763 1.0 1.0 4 Q9UBW7,Q01082,P62993 3 +Traf6 mediated nf kb activation 0.5112924034428459 0.5038244150589781 0.6143847691720516 1.0 1.0 4 P05067 1 +Synthesis of substrates in n glycan biosythesis 0.3844576125933827 0.4975126031597434 0.6188276175978527 1.0 1.0 14 P10619,Q86YN1 2 +Tnfr2 non canonical nf kb pathway 0.3607787251297333 0.4830083004991353 0.6290898425577893 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Dectin 1 mediated noncanonical nf kb signaling 0.3607787251297331 0.4830083004991318 0.6290898425577918 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Ldl clearance 0.3943961348323677 0.4804634826256971 0.6308978634014397 1.0 1.0 11 O15118 1 +Regulation of hmox1 expression and activity 0.3585526546928766 0.4709521125050128 0.6376749324473372 1.0 1.0 43 P09601,P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 11 +Scf skp2 mediated degradation of p27 p21 0.3588029908979024 0.4672738322742432 0.6403039757889943 1.0 1.0 40 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Polo like kinase mediated events 0.4968905472636754 0.4527844792696255 0.6507039408136106 1.0 1.0 4 O95067,Q99640,P53350 3 +G2 m dna replication checkpoint 0.4968905472636741 0.4527844792696212 0.6507039408136137 1.0 1.0 4 O95067,Q99640,P06493 3 +Downstream signal transduction 0.4409055189783205 0.4459415906732658 0.6556394382900885 1.0 1.0 6 P40763,P62993 2 +Signaling by pdgf 0.4409055189783205 0.4459415906732658 0.6556394382900885 1.0 1.0 6 P40763,P62993 2 +Synthesis of pips at the er membrane 0.5925962723572794 0.4418562063448593 0.6585932628144828 1.0 1.0 3 P42356 1 +Golgi to er retrograde transport 0.3078292294320791 0.4344023209110428 0.6639963126693733 1.0 1.0 73 Q9Y3B3,Q9H0H5,O75935,P24390,Q9Y496,Q15363,O15260,O43731,Q10472,Q9P2W9,O43264,Q9UJW0,Q13509 13 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.3545517257182564 0.4321566153411276 0.6656275889207839 1.0 1.0 40 Q03164,P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 10 +Ion homeostasis 0.397075369251067 0.4320760986289291 0.6656861055598324 1.0 1.0 10 P16615,P05023,Q12797 3 +Cardiac conduction 0.397075369251067 0.4320760986289291 0.6656861055598324 1.0 1.0 10 P16615,P05023,Q12797 3 +Degradation of gli1 by the proteasome 0.3543650885216252 0.43040529328993 0.6669008455242786 1.0 1.0 39 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 10 +Signaling by notch3 0.436838830118235 0.4288449308436223 0.6680360784239436 1.0 1.0 6 P42224,Q92542,Q13573,P67809,Q9Y6A5 5 +Peroxisomal protein import 0.34422918219536 0.4242647539332031 0.6713727408696553 1.0 1.0 24 O14975,Q15067,O15254,Q2T9J0,O14734,O75381,O15228 7 +Assembly of the hiv virion 0.7110006215040319 0.4190296842656615 0.6751944382794366 1.0 1.0 2 Q99816 1 +Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.4239028944911269 0.414955838398871 0.6781742320043396 1.0 1.0 7 Q07812,Q99873,P06493,P12004,P14635,Q86X55 6 +Camk iv mediated phosphorylation of creb 0.7050963331261719 0.403186955029068 0.686810695523234 1.0 1.0 2 P52292 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.7050963331261719 0.403186955029068 0.686810695523234 1.0 1.0 2 P52292 1 +The nlrp3 inflammasome 0.4821000477451433 0.4022632260441914 0.687490315368323 1.0 1.0 4 P09601 1 +Inflammasomes 0.4821000477451433 0.4022632260441914 0.687490315368323 1.0 1.0 4 P09601 1 +Purinergic signaling in leishmaniasis infection 0.4821000477451433 0.4022632260441914 0.687490315368323 1.0 1.0 4 P09601 1 +Signaling by hedgehog 0.3358648112267498 0.3906846291542119 0.696030361844332 1.0 1.0 58 P48556,P04350,Q96J02,P28074,P48729,Q13509,P49721,Q9Y496,P60900,Q9UBV2,P28070,O00231,P20618,Q13438,P28072,P10644,Q9BVA1,P61289,Q99436,O43242 20 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4389164902283684 0.3774724733391009 0.7058225171007908 1.0 1.0 5 P10321,P04439 2 +Gaba receptor activation 0.4725915418835297 0.3709066828269131 0.7107070374690889 1.0 1.0 4 Q9Y639 1 +Interferon gamma signaling 0.3744126344160109 0.3697579492190329 0.7115628496966973 1.0 1.0 11 Q13555,P18031,P19474,P10321,P04439 5 +Postmitotic nuclear pore complex npc reformation 0.334955360447098 0.3667917554964368 0.7137743578454823 1.0 1.0 23 Q12769,Q9BW27,Q9BTX1,Q8NFH5,Q8NFH4,Q8N1F7 6 +Hedgehog on state 0.3464908176661075 0.3666226282772631 0.71390052690779 1.0 1.0 41 P49721,P48556,P28070,Q9Y496,O00231,P20618,P28074,P28072,Q99436,P61289 10 +Diseases associated with glycosylation precursor biosynthesis 0.3941233424853035 0.3663690821674113 0.7140896871954479 1.0 1.0 9 P10619 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.3530136298298373 0.3648341737082266 0.7152351938482744 1.0 1.0 16 Q03518,Q9Y6B6,P51572,P27824,Q9NZ08,P10321 6 +N glycan trimming in the er and calnexin calreticulin cycle 0.3527981054914536 0.3635056914761309 0.7162271621018903 1.0 1.0 16 Q9BUN8,Q13438,O60858,P27824 4 +Metabolism of cofactors 0.4118175997871915 0.362445739252278 0.7170189646366993 1.0 1.0 7 P00374 1 +Fceri mediated nf kb activation 0.3458690244683818 0.3615422022757247 0.7176941625383013 1.0 1.0 41 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Signaling by ntrk3 trkc 0.6821006836544514 0.3444047087538908 0.7305419481625661 1.0 1.0 2 P62993 1 +Notch3 activation and transmission of signal to the nucleus 0.5562673331320103 0.3403862636748236 0.7335656617795949 1.0 1.0 3 Q92542 1 +Insulin receptor signalling cascade 0.4144394912687408 0.3377858644553179 0.7355245629678118 1.0 1.0 6 P31751 1 +Dap12 interactions 0.5548059234296675 0.336556014208283 0.7364516191413968 1.0 1.0 3 P10321 1 +Metabolism of polyamines 0.3423535575314501 0.3348236370447259 0.7377581288738244 1.0 1.0 38 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Signaling by notch 0.3325946378503275 0.332670305055459 0.7393831671340814 1.0 1.0 56 P49721,P48556,Q9HCE1,P28070,Q15363,O00231,P60900,P20618,P28074,P28072,Q99436,P16615,P61289 13 +Prolactin receptor signaling 0.5520671433012176 0.3294338412518617 0.7418277923770089 1.0 1.0 3 Q13616,P63208 2 +Regulation of ifna signaling 0.5520671433012136 0.3294338412518511 0.7418277923770169 1.0 1.0 3 P18031,P42224 2 +Regulation of ifng signaling 0.5520671433012136 0.3294338412518511 0.7418277923770169 1.0 1.0 3 P18031,P42224 2 +Interleukin 20 family signaling 0.5520671433012116 0.3294338412518461 0.7418277923770207 1.0 1.0 3 P40763,P42224 2 +Interferon alpha beta signaling 0.3941637933007118 0.3266748863296589 0.7439137968235214 1.0 1.0 8 Q9Y3Z3,P10321,P04439 3 +Noncanonical activation of notch3 0.6743318831572485 0.3256485568836889 0.7446902698816533 1.0 1.0 2 Q92542 1 +Switching of origins to a post replicative state 0.3318380179874504 0.3255146987149455 0.7447915598873256 1.0 1.0 56 P25205,P49721,P48556,P28070,O00231,Q9Y619,P60900,P20618,P28074,P28072,Q99436,P61289 12 +S phase 0.2765948460757259 0.3253093445601094 0.7449469592329507 1.0 1.0 94 Q9NRF9,P48556,Q9Y619,Q9Y248,P28074,P31751,Q7Z5K2,P49721,O75419,P60900,P49736,Q14691,P28070,O00231,P20618,P28072,P61289,P25205,P40938,Q99436 20 +Cdc42 gtpase cycle 0.3333871657159699 0.3130888144213216 0.7542131870063429 1.0 1.0 28 Q9H0H5,P42167,Q68EM7,Q9UQB8,Q14739,Q8TAA9,P27105 7 +Transport to the golgi and subsequent modification 0.2672301064386563 0.3120859775423129 0.7549751830099987 1.0 1.0 83 O75935,Q15363,O14653,P24390,Q13509,Q5JRA6,Q12893,P04066,O95249,O43731,Q9Y6B6,Q9UJW0,Q9Y3B3,P49755,O00743,Q9BVA1,Q96PC5,Q9HCU5,Q12907,Q96JB2 20 +Miro gtpase cycle 0.4075917859365435 0.3111223375916753 0.7557076203294892 1.0 1.0 6 Q96H55,P52306,Q8IWA4,O95140,Q8IXI1 5 +Activation of atr in response to replication stress 0.3339284164770038 0.3104202030480791 0.7562414326304143 1.0 1.0 18 P25205,P49736,Q9Y619,O75419 4 +Maturation of sars cov 1 nucleoprotein 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 1.0 2 P49840 1 +Copi mediated anterograde transport 0.3267457594752012 0.3020606960685865 0.7626057937554658 1.0 1.0 58 Q9Y3B3,Q96JB2,O75935,Q15363,O95249,O14653,O43731,P24390,Q13509 9 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.5404060295505508 0.2999455415761726 0.7642186955199968 1.0 1.0 3 Q7Z434 1 +Mapk3 erk1 activation 0.4468283582089475 0.290915611872314 0.7711158609243765 1.0 1.0 4 Q06124,P27361,P06493 3 +Signaling by erbb2 0.3762807211809115 0.2823718124053141 0.7776584263679296 1.0 1.0 9 Q16543,P31751 2 +Signaling by scf kit 0.3924680983504524 0.2820719330250031 0.7778883539455355 1.0 1.0 7 Q06124,P42224,P07948,P40763,P22681,P62993 6 +Intraflagellar transport 0.3498571030138511 0.2731098959726747 0.7847687399211554 1.0 1.0 13 P04350,Q9Y496,A0AVF1,Q9BVA1,Q13509 5 +Fatty acid metabolism 0.3175842938654651 0.2720490365328754 0.7855843149914095 1.0 1.0 62 Q9P035,P50416,P50897,O00767,Q53GQ0,P23786,O14975,Q9UKU0,Q6Y1H2,P49748,Q9NZ01,P51648,Q15165,Q9UMR5,Q709F0,P09960,Q15067,O95864,O15254,O43772,Q9H7Z7,Q14914,O14734,P33897,P54646 25 +Interleukin 21 signaling 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 1.0 2 P40763 1 +Interleukin 9 signaling 0.6504039776258617 0.2716011224178862 0.7859287363230238 1.0 1.0 2 P40763 1 +Translation of sars cov 2 structural proteins 0.3274207968156575 0.2692714075364942 0.7877208333231587 1.0 1.0 18 P78362,P46977,P49840,Q10472,P27824,P48729 6 +Regulation of tp53 expression and degradation 0.3551278186248429 0.2679580127877516 0.7887316381238907 1.0 1.0 11 P30154,O96017,P31751 3 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3329983445578696 0.2618289343269521 0.7934533306519507 1.0 1.0 45 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Synthesis of bile acids and bile salts 0.3869339997968933 0.260031705439059 0.7948393171761694 1.0 1.0 7 O14975 1 +Bile acid and bile salt metabolism 0.3869339997968933 0.260031705439059 0.7948393171761694 1.0 1.0 7 O14975 1 +Cytosolic sulfonation of small molecules 0.4051811311623264 0.2586108433614077 0.7959355160119257 1.0 1.0 5 Q8TB61 1 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3192603982356784 0.2576568780561089 0.7966717289317393 1.0 1.0 23 P22626,O14979,P52597,Q13126,P78417 5 +Ub specific processing proteases 0.303902587298434 0.2482796208648987 0.8039180656452241 1.0 1.0 68 Q96K76,P49721,P48556,Q9Y277,P28070,P21796,O00231,P20618,P28074,P28072,Q99436,P45880,O14964,P61289 14 +Regulation of signaling by cbl 0.3996889580093257 0.240697002380019 0.8097899624332217 1.0 1.0 5 P22681,P46108,P07948,P62993 4 +Activation of the pre replicative complex 0.3106998108276356 0.2325011627869959 0.8161487841852941 1.0 1.0 20 P25205,Q9Y619,O75419 3 +Negative regulation of the pi3k akt network 0.3420764045958524 0.2315191245682751 0.8169115297302509 1.0 1.0 13 Q8TBX8,P31751,O43815,P62993 4 +Circadian clock 0.3647706263951321 0.2307174839948635 0.8175342896801088 1.0 1.0 9 P43490,P50416,Q9BWF3 3 +Synthesis of pips at the golgi membrane 0.3783764718345466 0.2268685885297497 0.8205259279408827 1.0 1.0 7 Q10713,P42356,Q9NTJ5 3 +Dna replication pre initiation 0.3149999499765116 0.2160293198926277 0.8289648931640512 1.0 1.0 60 Q9NRF9,P25205,P49721,P48556,P28070,O00231,Q9Y619,O75419,P60900,P20618,P28074,P28072,Q99436,P61289 14 +Interleukin 12 family signaling 0.319112527732184 0.2123448813990501 0.8318379834018985 1.0 1.0 28 P22626,O14979,P52597,Q13126,P78417,P27824 6 +Rora activates gene expression 0.5014775382394775 0.2119977687629941 0.8321087750323555 1.0 1.0 3 P50416 1 +Ptk6 regulates cell cycle 0.6180857675574994 0.2080048073526162 0.8352252137260632 1.0 1.0 2 P11802 1 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.4976686353745821 0.2043093949131822 0.8381117287387028 1.0 1.0 3 O43865,P62993 2 +Regulation of kit signaling 0.497668635374582 0.2043093949131819 0.838111728738703 1.0 1.0 3 P22681,P62993 2 +Phosphorylation of emi1 0.4967360895244113 0.202452790435951 0.8395627619246764 1.0 1.0 3 P53350,P06493 2 +Nuclear envelope ne reassembly 0.3222556172898612 0.2019712573689832 0.839939194402946 1.0 1.0 52 P50402,Q86XL3,Q12769,P42167,Q8IXJ6,Q9BW27,Q8NFH3,Q9BTX1,Q8NFH5,P42166,Q8NFH4,Q9BVA1,Q14739,Q8N1F7,Q13509 15 +Interleukin 1 signaling 0.3249648707495106 0.1953017648967634 0.8451567154880966 1.0 1.0 44 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,O43242,P61289 11 +Receptor mediated mitophagy 0.4930606101776759 0.1952344513879553 0.8452094096553904 1.0 1.0 3 Q96HS1 1 +Beta oxidation of very long chain fatty acids 0.3744316516785412 0.1913637811022794 0.8482405941478446 1.0 1.0 6 Q15067,O14734 2 +Formation of tubulin folding intermediates by cct tric 0.3304922910589331 0.1881366341808411 0.8507695439010048 1.0 1.0 14 Q9BVA1,Q99832,P04350,Q13509 4 +Transport of bile salts and organic acids metal ions and amine compounds 0.4085191525755192 0.1874834987983938 0.8512815603498975 1.0 1.0 4 Q9H2J7,P53985 2 +Neurotransmitter receptors and postsynaptic signal transmission 0.3203157783296221 0.1823788202778766 0.8552854460236796 1.0 1.0 34 Q9Y639,P10644,P63096,P07196,P54646,Q15418,Q13509 7 +Tcr signaling 0.322896180178951 0.1789537038385636 0.8579740537705043 1.0 1.0 44 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Pre notch expression and processing 0.3432503474925225 0.1693230499219703 0.8655425465292139 1.0 1.0 10 Q15363,P16615,Q9HCE1 3 +Calnexin calreticulin cycle 0.3499912808682363 0.1677914835542145 0.8667473226499902 1.0 1.0 9 Q13438,O60858,P27824 3 +Interleukin 12 signaling 0.3076231700161927 0.1611224025570982 0.8719969960760998 1.0 1.0 25 P22626,O14979,P52597,Q13126,P78417 5 +Pten regulation 0.308484457653903 0.1538632962746119 0.8777175247525428 1.0 1.0 60 P49721,P48556,Q9HCE1,P28070,O00231,P60900,P20618,P28074,P31751,P28072,Q99436,P61289 12 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.470003108486172 0.1536032523437388 0.8779225723769684 1.0 1.0 3 P11802,P24941 2 +Constitutive signaling by aberrant pi3k in cancer 0.3697981638120916 0.1513775021177955 0.8796779356473192 1.0 1.0 5 O43815 1 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.3921019900497445 0.1495570394109281 0.8811141044522941 1.0 1.0 4 P61586,Q96JJ3,P46108 3 +G alpha i signalling events 0.2973541858558626 0.1476358917992438 0.882630127915381 1.0 1.0 20 Q9NRV9,P07602,P10644,Q9NZJ7 4 +Integrin cell surface interactions 0.3910514532073079 0.1472686216344751 0.8829199987073812 1.0 1.0 4 Q08722 1 +Beta catenin independent wnt signaling 0.3155647074150485 0.1390814601015826 0.8893857785234973 1.0 1.0 51 P49721,P48556,Q9HCE1,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,Q9ULK5,P61289 12 +Apc c mediated degradation of cell cycle proteins 0.3122759005338886 0.129275666809645 0.897139524922623 1.0 1.0 54 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,O60566,P61289 10 +Unblocking of nmda receptors glutamate binding and activation 0.3584521591934996 0.1213818233275782 0.9033886133043924 1.0 1.0 5 P07196,Q14168 2 +Ras activation upon ca2 influx through nmda receptor 0.3584521591934996 0.1213818233275782 0.9033886133043924 1.0 1.0 5 P07196,Q14168 2 +Long term potentiation 0.3584521591934996 0.1213818233275782 0.9033886133043924 1.0 1.0 5 P07196,Q14168 2 +Rhoh gtpase cycle 0.2966065576586941 0.121287475009024 0.9034633402727172 1.0 1.0 22 Q8TAA9,Q9BXS4,Q9Y6M7 3 +Map3k8 tpl2 dependent mapk1 3 activation 0.4466894622319026 0.1179683158891549 0.9060927628031584 1.0 1.0 3 Q13616,P63208 2 +Fbxw7 mutants and notch1 in cancer 0.5565568676196524 0.1179548905351701 0.9061034004168862 1.0 1.0 2 P63208 1 +Rac3 gtpase cycle 0.3100192929943215 0.1104937924037706 0.9120177726710283 1.0 1.0 34 Q9H0H5,P50402,P42167,O15173,Q68EM7,Q9UQB8,Q14739,Q8TAA9 8 +Notch3 intracellular domain regulates transcription 0.4364314578800181 0.1043286936447524 0.9169085079215882 1.0 1.0 3 Q13573,P42224 2 +Rnd3 gtpase cycle 0.3028808506636853 0.1003757006308529 0.9200460604109004 1.0 1.0 17 Q9Y2I1,Q9ULK5,Q8TAA9 3 +Negative regulators of ddx58 ifih1 signaling 0.3416828003819162 0.0991295007008065 0.9210354492681458 1.0 1.0 7 Q86UT6,Q7Z434 2 +Degradation of beta catenin by the destruction complex 0.3119456625331273 0.0987483095748184 0.9213381107865906 1.0 1.0 48 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Deubiquitination 0.2540722260112533 0.0976164846748296 0.9222368341468812 1.0 1.0 86 P48556,Q7Z434,P28074,O14964,P21796,Q96K76,P49721,Q9Y277,P60900,P45880,Q8NB78,P45974,P28070,Q13546,O00231,P20618,P28072,P61289,Q15388,Q99436,O43242,P54725 22 +Ripk1 mediated regulated necrosis 0.3193524339600402 0.0974232913178231 0.9223902489092376 1.0 1.0 11 O00560,Q9UNE7,Q13546,Q16543,O75955 5 +Met activates ras signaling 0.3643933956135042 0.0949108108868261 0.9243856694402242 1.0 1.0 4 Q96S59,P62993 2 +Heme biosynthesis 0.3470803088784421 0.0936239810807341 0.9254078591362108 1.0 1.0 5 Q7KZN9,P22830 2 +Pi5p regulates tp53 acetylation 0.4233758159776299 0.0887266206295276 0.9292991757641436 1.0 1.0 3 Q8TBX8,Q13526 2 +Regulation of tp53 activity through methylation 0.4233758159776276 0.0887266206295248 0.9292991757641458 1.0 1.0 3 O96017,O14744 2 +Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.4233758159776239 0.0887266206295206 0.9292991757641492 1.0 1.0 3 P53611,Q92696 2 +Tp53 regulates transcription of genes involved in cytochrome c release 0.4233758159776228 0.0887266206295195 0.92929917576415 1.0 1.0 3 Q07812,Q9Y255 2 +Energy dependent regulation of mtor by lkb1 ampk 0.3340597758405951 0.0880411056502425 0.9298440053856396 1.0 1.0 8 P54619,P42345,P49815,Q9Y2Q5,P54646,Q9Y376,Q6IAA8 7 +Arms mediated activation 0.5229956494717355 0.0852422853883742 0.9320687740186786 1.0 1.0 2 P46108 1 +Peptide hormone metabolism 0.3143849393855785 0.0840039851566251 0.9330532632736116 1.0 1.0 12 Q15005,P67812,P61009 3 +Tp53 regulates transcription of cell death genes 0.3369632856253864 0.0784583229665521 0.9374634814395516 1.0 1.0 6 Q07812,P04637,Q92696,P53611,Q9Y255 5 +Autophagy 0.3085021960683503 0.077126275415299 0.9385230904940512 1.0 1.0 50 Q96HS1,P04350,P50542,Q9NS69,P13473,O96008,Q15388,O94826,Q8IWA4,P54646,Q9BVA1,Q99816,P08670,P21796,Q8N4H5,Q13509 16 +Formyl peptide receptors bind formyl peptides and many other ligands 0.4051845599496786 0.0701440119505718 0.9440790364776286 1.0 1.0 3 Q9NRV9 1 +Asparagine n linked glycosylation 0.2802867589005726 0.068607932047747 0.9453017048859648 1.0 1.0 125 Q86SQ9,O60858,O75935,Q15363,O14653,P10619,P24390,O75340,Q13509,Q9BT22,Q5JRA6,Q12893,P04066,O95249,O43731,Q9BV10,Q9Y6B6,Q9UJW0,Q9Y3B3,Q9UBV2,Q86YN1,P49755,Q13438,O00743,Q9BVA1,P27824,Q9HCU5,Q96PC5,Q12907,Q96JB2,P16278,Q9BUN8,P46977 33 +Pecam1 interactions 0.4975139838409101 0.0671568849116727 0.9464568084524964 1.0 1.0 2 Q06124 1 +Erythropoietin activates ras 0.3994404724899025 0.0650054797060206 0.948169637310664 1.0 1.0 3 P07948,P62993 2 +Signaling by erythropoietin 0.3994404724899025 0.0650054797060206 0.948169637310664 1.0 1.0 3 P07948,P62993 2 +Free fatty acids regulate insulin secretion 0.4897451833437021 0.0626662490784915 0.9500322738813844 1.0 1.0 2 O60488 1 +Signaling by ntrk2 trkb 0.3919801056885367 0.058829203371357 0.9530881478091302 1.0 1.0 3 Q06124,P62993 2 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3059307461888624 0.05734315868427 0.9542718412341312 1.0 1.0 40 Q14103,P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,P61289 11 +Other interleukin signaling 0.4735860783095235 0.0546875542544702 0.9563873847908946 1.0 1.0 2 Q12846 1 +Alk mutants bind tkis 0.3265703389442318 0.0519737508088521 0.9585496089571444 1.0 1.0 6 P10644 1 +Suppression of apoptosis 0.3361981245701235 0.0515299947213733 0.9589032012626088 1.0 1.0 4 P23246 1 +Biological oxidations 0.3058738334729012 0.0496738054381995 0.9603823309143564 1.0 1.0 44 Q16850,Q8TB61,O43169,P78417,P16435,Q9NUJ1,P21964 7 +Clec7a dectin 1 signaling 0.3055090709782841 0.0470182790635673 0.9624986590535878 1.0 1.0 44 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P61289 9 +Tryptophan catabolism 0.4515226848974688 0.0464041997325402 0.9629880892182724 1.0 1.0 2 P08195 1 +Er to golgi anterograde transport 0.2566923527822914 0.0450003687324257 0.9641070150475476 1.0 1.0 80 O75935,Q15363,O14653,P24390,Q13509,Q5JRA6,Q12893,O95249,O43731,Q9Y6B6,Q9UJW0,Q9Y3B3,P49755,O00743,Q9BVA1,Q96PC5,Q9HCU5,Q12907,Q96JB2 19 +Rip mediated nfkb activation via zbp1 0.3720857942182184 0.0449409457466738 0.964154379811903 1.0 1.0 3 Q08211,Q13546 2 +Zbp1 dai mediated induction of type i ifns 0.3720857942182184 0.0449409457466738 0.964154379811903 1.0 1.0 3 Q08211,Q13546 2 +Intracellular signaling by second messengers 0.256647983405423 0.0444440387424223 0.964550458469594 1.0 1.0 80 P49721,P48556,P28070,O00231,O43815,P60900,P20618,P28074,P31751,P10644,P28072,Q99436,P61289 13 +Interleukin 1 family signaling 0.3048036873344321 0.0420332644706643 0.9664721803284582 1.0 1.0 47 P49721,P48556,P28070,O00231,P60900,P20618,P28074,P28072,Q99436,O43242,P61289 11 +Notch4 activation and transmission of signal to the nucleus 0.4207582349285422 0.0388552301343355 0.9690058107694428 1.0 1.0 2 Q92542 1 +Wnt mediated activation of dvl 0.4117464263517845 0.0373331992025708 0.970219334800049 1.0 1.0 2 P67870 1 +Crmps in sema3a signaling 0.3233830845771089 0.035764049121767 0.9714704993616838 1.0 1.0 4 Q16555,P49841,Q9BPU6 3 +Dap12 signaling 0.3918582970789441 0.0348106110077685 0.9722307594001148 1.0 1.0 2 P62993 1 +Rac1 gtpase cycle 0.3028986929234161 0.0335247439169778 0.9732561341270792 1.0 1.0 41 Q9H0H5,P50402,P42167,Q68EM7,Q9UQB8,Q9Y2I1,Q14739,Q8TAA9 8 +Regulation by c flip 0.3365444375388557 0.0316868048289531 0.9747218178248772 1.0 1.0 2 Q13546 1 +Caspase activation via death receptors in the presence of ligand 0.3365444375388557 0.0316868048289531 0.9747218178248772 1.0 1.0 2 Q13546 1 +Interleukin 7 signaling 0.2964574269732877 0.0311175348868291 0.9751758056234716 1.0 1.0 2 P40763 1 +Met activates pi3k akt signaling 0.2924176507147423 0.0310923097546627 0.9751959226328504 1.0 1.0 2 P62993 1 +Regulation of innate immune responses to cytosolic dna 0.3413117811625776 0.0299107596562586 0.9761382247250594 1.0 1.0 3 P19474,Q9NZI8 2 +Gab1 signalosome 0.3372707491451701 0.0284335577040359 0.9773163598369504 1.0 1.0 3 Q06124,P62993 2 +Caspase activation via extrinsic apoptotic signalling pathway 0.3366490519117223 0.0282153474350789 0.9774903966145664 1.0 1.0 3 Q9UKG1,Q13546 2 +Ncam signaling for neurite out growth 0.3120075342529197 0.0230859492420856 0.9815817135810104 1.0 1.0 5 P62993,Q13813 2 +Mrna decay by 3 to 5 exoribonuclease 0.2925138628431548 0.0182141490665673 0.9854680151863846 1.0 1.0 15 Q969T7,Q96B26 2 +Met activates ptpn11 0.2925085483369649 0.0178143378352382 0.9857869666368342 1.0 1.0 3 Q06124,P62993 2 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.2829067381712181 0.017463094162364 0.986067174945862 1.0 1.0 18 Q99832,P68371,P04350,Q9BVA1,Q13509 5 +Signal attenuation 0.2747901771837161 0.0157517202735839 0.987432465292293 1.0 1.0 3 P27361,P62993 2 +Rhog gtpase cycle 0.2937320914041321 0.004317161311465 0.9965554143430532 1.0 1.0 34 Q14739,Q86XL3,O15173 3 +Heme signaling 0.2838971802877001 0.0011196220213277 0.999106671061887 1.0 1.0 4 P09601 1 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b9e7a2fed6cc23dcbe648d093e4852ceb8f6e746 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodeling of dag and tag", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha defensins", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "Butyrophilin btn family interactions", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd22 mediated bcr regulation", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Defensins", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phosphoinositide 3 kinase pi3k", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Erythropoietin activates stat5", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retinoid cycle disease events", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "Runx3 regulates yap1 mediated transcription", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 27 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Yap1 and wwtr1 taz stimulated gene expression", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO10", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "APOBEC3C", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BRK1", "BSG", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDS2", "CENPH", "CENPI", "CENPP", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTC", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG3", "COG4", "COG7", "COG8", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ9", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF2", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP3", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISCU", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JUP", "KARS", "KCMF1", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC1", "LRRFIP1", "LRSAM1", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LYN", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN2A1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MARC1", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL14", "METTL3", "MFN1", "MFN2", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1C", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEK9", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NXF1", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PECR", "PELP1", "PES1", "PEX11A", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "POFUT1", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RALA", "RALB", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RBBP5", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM8A", "RBMX", "RBP1", "RCC1", "RCC2", "RCL1", "RCN1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RNASET2", "RNF40", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP8", "RRP9", "RSF1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SDHC", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A1", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMDT1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORT1", "SPAG9", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX17", "STX18", "STX4", "STX5", "STX6", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM11", "TMEM115", "TMEM59", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRMT1", "TRMT10C", "TRMT11", "TRMT6", "TRMT61A", "TRMU", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXN2", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBIAD1", "UBQLN2", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UPF1", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VANGL2", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS29", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "WAPL", "WARS", "WASF2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR46", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YKT6", "YME1L1", "YOD1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZSWIM8", "ZW10"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ABCD3", "ABHD10", "ACAD11", "ACADVL", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL4", "ACSL6", "ACTR1A", "ADD3", "ADI1", "AGPAT5", "AHCYL1", "AKT1S1", "AKT2", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "ANO10", "ANO6", "APOO", "APOOL", "APP", "APPL1", "ARHGAP17", "ARL2", "ARV1", "ASAH1", "ASPH", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "B4GAT1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BSG", "BUB1B", "C19orf70", "CAB39", "CALU", "CAMK2G", "CANX", "CARM1", "CBL", "CCNB1", "CCNB2", "CCT7", "CD47", "CDC37", "CDC45", "CDIPT", "CDK1", "CDK2", "CDK4", "CDS2", "CERS1", "CERS2", "CETN2", "CHEK2", "CHKA", "CHST14", "CKAP4", "CLASP1", "CLCN3", "CLCN7", "COG3", "COMT", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX6C", "COX7A2L", "CPSF6", "CPT1A", "CPT2", "CRK", "CSNK1A1", "CSNK2B", "CTSA", "CUL1", "CYB5B", "CYP51A1", "DCTN3", "DCTN4", "DERL1", "DHCR24", "DHDDS", "DHFR", "DHRS7B", "DHX9", "DNAJC11", "DNAJC3", "DOHH", "DOLPP1", "DPYSL2", "DPYSL5", "EBP", "ECE1", "ELMO2", "EMD", "ENDOD1", "ERAP1", "ETFDH", "ETNK1", "EXOSC3", "EXOSC8", "FADS2", "FAM3C", "FAM49B", "FECH", "FGFR1OP", "FKBP14", "FKBP1A", "FLOT1", "FNTB", "FUCA1", "FUCA2", "GALNT1", "GALNT4", "GBA", "GGCX", "GINS1", "GINS2", "GLA", "GLB1", "GLG1", "GM2A", "GNAI1", "GNPAT", "GOLGA5", "GOLIM4", "GOSR1", "GOSR2", "GPAA1", "GPX8", "GRB2", "GSK3A", "GSK3B", "GSR", "GSTO1", "HACD2", "HACD3", "HAUS1", "HAUS4", "HAUS5", "HEBP1", "HEXA", "HGS", "HIGD1A", "HLA-A", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPD", "HNRNPDL", "HNRNPF", "HS2ST1", "HSD17B12", "ICMT", "IGF2BP1", "IRS4", "ITCH", "KDELR1", "KDELR3", "KDM1B", "KHDRBS1", "KHSRP", "KIF3A", "KMT2A", "KPNA2", "L2HGDH", "LAMP2", "LAMTOR1", "LAMTOR2", "LBR", "LGALS3BP", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "LPCAT3", "LSS", "LTA4H", "LYN", "MAPK3", "MAPRE1", "MAVS", "MBOAT7", "MCM2", "MCM3", "MCM6", "MFN1", "MFN2", "MIA2", "MIA3", "MICU2", "MIF", "MIPEP", "MMAB", "MMGT1", "MOV10", "MPP2", "MSMO1", "MTAP", "MTCH1", "MTOR", "MTX1", "MTX2", "MYO19", "NAA35", "NAGLU", "NAMPT", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB9", "NDUFS2", "NDUFS7", "NEFL", "NISCH", "NLRX1", "NNT", "NPC1", "NPTN", "NT5C3B", "NUCB1", "NUP160", "NUP35", "NUP37", "NUP43", "NUP85", "NUP93", "OLA1", "OS9", "PARL", "PCM1", "PCNA", "PCYOX1L", "PDCD6", "PDE6D", "PELP1", "PEX11A", "PEX14", "PEX16", "PEX3", "PEX5", "PGAM5", "PGRMC2", "PI4KA", "PIGL", "PIGU", "PIN1", "PIP4K2C", "PISD", "PKMYT1", "PLA2G15", "PLD3", "PLD6", "PLK1", "PMPCA", "PNPLA8", "POLE3", "PON2", "POR", "PPP2R1B", "PPP6C", "PPT1", "PPT2", "PREB", "PRELID1", "PRKAA2", "PRKAG1", "PRKAR1A", "PRMT1", "PRMT5", "PSAP", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSMD3", "PSMD8", "PSME2", "PSME3", "PTDSS2", "PTGES2", "PTGR1", "PTPMT1", "PTPN1", "PTPN11", "PXMP2", "RABGGTA", "RABGGTB", "RACGAP1", "RAD23A", "RANBP9", "RAP1GDS1", "RBM14", "RBM4", "RBP1", "RDH13", "RETSAT", "RFC3", "RHOA", "RHOT2", "RIPK1", "RPS6KA1", "RPS6KA3", "RRM2", "SACM1L", "SAMHD1", "SAMM50", "SAR1B", "SC5D", "SCARB1", "SCCPDH", "SCD", "SDCBP", "SDHB", "SDHC", "SEC11A", "SEL1L", "SELENOI", "SFPQ", "SGPL1", "SIRT2", "SKP1", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC33A1", "SLC35B2", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMDT1", "SNW1", "SOAT1", "SPCS2", "SPCS3", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SRPK2", "SRPRB", "SSNA1", "SSR1", "STARD3NL", "STARD7", 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0000000000000000000000000000000000000000..62c0f5296305c590e56614b923088269ed4ebc68 --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd7ab304b7aa34809d1eeeb94324a592deb00ba47d38915cefce6b2d36815802 +size 87136 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8e25b10348c734ccf54df91e8dd9d12c1e198635 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial complex iv assembly 7 16 2.9772656570520653 0.0029083188507499 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 0.0005015429832077 0.1541506060207377 0.2851312580635185 0.0012324742743759 0.0001729005795719 +Sphingolipid metabolism integrated pathway 6 9 2.482848306363617 0.0130336577496308 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0189572928019038 1.0 0.1709159600444602 0.0101015401572799 0.0118865434534573 +Sphingolipid metabolism overview 6 9 2.482848306363617 0.0130336577496308 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.013913202095476 1.0 0.1543818096433915 0.0073447144383531 0.0078812527225172 +Cholesterol metabolism with bloch and kandutschrussell pathways 10 25 2.4488938068109123 0.0143295688798699 7.092233009708738 23.070388349514563 1.3045876527781233 0.2885598195159411 3.1892169450204397 2.132138915277104 1.1515799969949023 0.3088028425519339 0.0001075189267489 0.0007667347448651 2.788863476938184e-05 0.0002303056568621 8.556622581523825e-07 +Sphingolipid metabolism in senescence 6 11 2.4321200750570227 0.0150107301135862 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.0316907975050379 1.0 0.2030300441679912 0.0172025832638257 0.0233101974365333 +Oxidation by cytochrome p450 3 7 2.4086308702096964 0.0160124842117548 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0064033235801391 0.0619434524836269 0.1203280145079081 0.0033170374819039 0.0027630263410089 +Electron transport chain oxphos system in mitochondria 24 56 2.361150748485186 0.0182183231890684 17.57766990291262 50.45631067961165 1.00621396752225 0.3125021459260491 7.648293572467493 4.538458527560961 1.9412236823915887 0.3642771965747766 9.576275082332132e-05 7.825109144978314e-05 0.0019601767571855 6.439621012544542e-05 2.87785716218875e-07 +Cholesterol biosynthesis with skeletal dysplasias 5 7 2.278208135742625 0.0227141797858536 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 2.763666768013992e-05 0.0004872428921227 3.114096148731792e-05 1.093284607508717e-05 8.537649759126899e-08 +Kennedy pathway from sphingolipids 4 6 2.2696271412578897 0.0232302154207493 1.8349514563106797 4.538834951456311 1.005685357170638 0.2842758763214292 1.1414272055653287 1.0616650240280194 1.1079123437614409 0.2814205551839854 0.0079677731040502 0.066549445548378 0.1289666473793992 0.0435926191526008 0.0003671727016274 +Sphingolipid pathway 6 10 2.1704373487047963 0.0299737300001594 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.0040207313875964 1.0 0.1951188871774342 0.0017174581383874 0.0034992238505004 +Glycerolipids and glycerophospholipids 5 7 1.9899973846364305 0.0465912236038827 1.902439024390244 5.282926829268293 0.2570184705733445 0.3919307408190254 1.3234264111744822 1.6756363827898255 1.2288051208295987 0.2955621473168567 0.4621242220262765 0.0937235599037543 0.179062604831997 0.3867116248199588 0.0143001062154138 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..15060aab922cd3063ea850adebb3dc801ee899ce --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 596, + "title": "Average number of proteins per term", + "value": 10.590604026845638 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..28701e9604268da9bc618f1e77728315854b15c9 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..28bbe0e1ccf467f3edf6ac62b19615804cd51c18 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,141 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial complex iv assembly 0.7651469278262557 2.9772656570520653 0.0029083188507499 0.8237555825359277 0.6835586327967373 16 Q8N8Q8,Q9Y2R0,Q7KZN9,Q9P0S2,Q9Y241,P13073,P14406 7 +Sphingolipid metabolism integrated pathway 0.798908397986992 2.482848306363617 0.0130336577496308 0.9995980276896184 0.6835586327967373 9 P27544,Q16739,O15269,O95470,Q96G23,Q13510 6 +Sphingolipid metabolism overview 0.798908397986992 2.482848306363617 0.0130336577496308 0.9995980276896184 0.6835586327967373 9 P27544,Q16739,O15269,O95470,Q96G23,Q13510 6 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.6162265342697784 2.4488938068109123 0.0143295688798699 0.9998162995748622 0.6835586327967373 25 Q15125,P48449,Q16850,Q9BWD1,Q14534,P35610,Q15800,O75845,Q14739,Q15392 10 +Sphingolipid metabolism in senescence 0.7325425109385219 2.4321200750570227 0.0150107301135862 0.9998783327508936 0.6835586327967373 11 P16278,P04062,Q16739,O15269,Q96G23,Q13510 6 +Oxidation by cytochrome p450 0.8392947235128254 2.4086308702096964 0.0160124842117548 0.9999336570630064 0.6835586327967373 7 Q6UW02,O43169,Q16850 3 +Electron transport chain oxphos system in mitochondria 0.5443823459058132 2.361150748485186 0.0182183231890684 0.9999825861893256 0.6835586327967373 56 O43676,P03886,O14949,P00846,P05141,O75306,O95139,O75964,P14406,Q99643,P24539,Q7KZN9,Q9UDW1,P13073,O14548,Q9Y6M9,Q9Y6N1,P56385,O75251,P12236,P12235,P22695,P21912,O75947 24 +Cholesterol biosynthesis with skeletal dysplasias 0.8104276519604422 2.278208135742625 0.0227141797858536 0.9999988705367612 0.6835586327967373 7 Q15125,Q16850,O75845,Q14739,Q15392 5 +Kennedy pathway from sphingolipids 0.8359369574749956 2.2696271412578897 0.0232302154207493 0.999999175556052 0.6835586327967373 6 Q9HBU6,P35790,Q9BVG9,O95470 4 +Sphingolipid pathway 0.7102714968247413 2.1704373487047963 0.0299737300001594 0.9999999867271696 0.6835586327967373 10 P04062,Q16739,O15269,O95470,Q96G23,Q13510 6 +Glycerolipids and glycerophospholipids 0.748150364053084 1.9899973846364305 0.0465912236038827 0.9999999999995528 0.6835586327967373 7 Q9BVG9,Q9HBU6,P48651,O14735,Q9UG56 5 +Metabolism of spingolipids in er and golgi apparatus 0.7635470408030788 1.9472029165261768 0.0515104121838352 0.9999999999999796 0.6835586327967373 6 Q10472,O95470,Q16739 3 +Degradation pathway of sphingolipids including diseases 0.760810716705609 1.934792998689072 0.0530157026021389 0.999999999999992 0.6835586327967373 6 P17900,P06865,P06280 3 +Statin inhibition of cholesterol production 0.8512335633720342 1.8839452220446753 0.0595723853924776 1.0 0.6835586327967373 4 P35610,Q8WTV0 2 +Familial partial lipodystrophy fpld 0.677161385123286 1.8729956077341483 0.0610689915191415 1.0 0.6835586327967373 9 O75844,O60725 2 +7oxoc and 7betahc pathways 0.6239657263670078 1.833686212743907 0.0667005863726493 1.0 0.6982118734331219 11 O14975,Q15125,Q9UBM7,O15118 4 +Mitochondrial complex iii assembly 0.635603821827423 1.7702838900861937 0.0766798603866762 1.0 0.6982118734331219 10 P22695,Q9UDW1,O14949 3 +Glycerophospholipid biosynthetic pathway 0.7012138188608622 1.7667328168828664 0.0772729847017925 1.0 0.6982118734331219 7 Q8WUK0,O95674,P48651,O14735,Q9BTU6,O15228 6 +S1p receptor signal transduction 0.6727612509141168 1.7419017367030871 0.081525640020633 1.0 0.6982118734331219 8 Q13510,P31751,P63096 3 +Omega3 omega6 fatty acid synthesis 0.7169627331558163 1.733825209098195 0.0829491013209493 1.0 0.6982118734331219 6 Q15067,O15254 2 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5649421989555097 1.6430674675833286 0.1003689749378171 1.0 0.6993475739494799 14 P50402,O60725,P42167,O75844,P49354,P42166,P55209 7 +Vitamin a and carotenoid metabolism 0.7919355019233061 1.6420982167192015 0.1005696512023213 1.0 0.6993475739494799 4 P09455,Q8WTV0 2 +Serine metabolism 0.694949142197826 1.6315137570295208 0.102781959445608 1.0 0.6993475739494799 6 O43175 1 +Adipogenesis 0.5427551824718955 1.624401395148929 0.1042901695265732 1.0 0.6993475739494799 16 O75844,Q9NZ45 2 +Alzheimers disease and mirna effects 0.3725919423109509 1.6049031903903903 0.1085151113403177 1.0 0.7184081559475644 80 P05067,P48556,P28074,P31751,O95197,P05141,P21796,Q13509,P49721,Q9Y277,P60900,Q9NQC3,P45880,O14654,P28070,P20618,P28072,P16615,Q9BVA1,P12236,P12235,Q96IX5,Q99436,O43242 24 +Proteoglycan biosynthesis 0.68811829910451 1.5995887946591658 0.1096898358913227 1.0 0.7184081559475644 6 O43909,Q8TB61,Q8NCH0,Q9NX62 4 +Glycosaminoglycan degradation 0.7057363355856265 1.5406791287140356 0.1233948989024231 1.0 0.7437198843191688 5 P54802,P16278,P06865 3 +Eicosanoid synthesis 0.8893378924463784 1.4952276864848228 0.1348550301816349 1.0 0.7437198843191688 3 P09960,Q9NP80 2 +Mitochondrial immune response to sarscov2 0.605378551881737 1.4941346154454695 0.1351404380625287 1.0 0.7437198843191688 9 Q9Y6M9,Q86UT6,O94826,Q7Z434 4 +Metapathway biotransformation phase i and ii 0.4848350232244189 1.490792867785821 0.1360158848838748 1.0 0.7437198843191688 27 Q16850,Q8NCH0,Q7LGA3,Q6UW02,Q9NRB3,P78417,P21964 7 +Nonalcoholic fatty liver disease 0.456099086108594 1.4746008834316704 0.1403198772658567 1.0 0.7546827540279523 53 O75306,O43676,O75251,O95139,Q86Y39,Q9UDW1,P21912,P31751,P13073,O14949,O14548,Q9NX14,Q9Y6M9,P22695,P14406,Q99643,P54646 17 +Alzheimers disease 0.366375765137289 1.4615623612807156 0.1438611749012603 1.0 0.7655469664388499 79 P05067,P48556,P28074,P31751,O95197,P05141,P21796,Q13509,P49721,Q9Y277,P60900,Q9NQC3,P45880,O14654,P28070,P20618,P28072,P16615,Q9BVA1,P12236,P12235,Q99436,O43242 23 +Triacylglyceride synthesis 0.6485419849429589 1.4131604336666297 0.1576085572483814 1.0 0.782789167666961 6 Q9NUQ2,O15228,O00116,O15120 4 +Nanomaterial induced apoptosis 0.6718630488787364 1.3886590593177863 0.1649364491475486 1.0 0.7885151561267504 5 O95831 1 +Oxysterols derived from cholesterol 0.5667212174414543 1.38673019348517 0.1655240500972032 1.0 0.7885151561267504 10 O14975,Q15125,Q9UBM7 3 +Cholesterol biosynthesis pathway 0.5314036571037206 1.3816993160185975 0.1670640445052651 1.0 0.7885151561267504 13 P48449,Q16850,Q14534,O75845,Q15800 5 +Acquired partial lipodystrophy barraquersimons syndrome 0.6696276959982084 1.3785857102270913 0.1680225248793578 1.0 0.7885151561267504 5 P49354,O60725,Q03252 3 +Vitamin d metabolism 0.8526577556729766 1.3576123674912048 0.174586716538142 1.0 0.8001596734044708 3 P04062,P38435 2 +Influence of laminopathies on wnt signaling 0.5611093159406257 1.3549749317316435 0.175425544034951 1.0 0.8001596734044708 10 O75844 1 +Progeriaassociated lipodystrophy 0.5587025611093822 1.3413370931861388 0.1798110317416585 1.0 0.8001596734044708 10 O75844 1 +Vitamin d receptor pathway 0.5221263884440965 1.27881471929208 0.2009623093238235 1.0 0.8117250564740932 12 P08183,Q5VV42,Q96KA5,P33897,P20020 5 +Relationship between inflammation cox2 and egfr 0.6976989468651646 1.250705094907628 0.211042090948724 1.0 0.8157055362300466 4 P31751 1 +Oxidative phosphorylation 0.4531407668640141 1.243015761787131 0.2138620253121925 1.0 0.8157055362300466 34 O75306,Q15904,O75251,O95139,P03886,P24539,Q9Y6M9,Q86Y39,O75964,P00846,O75947,O95167,P56385 13 +Ferroptosis 0.4502371631140195 1.2256723727056191 0.2203219907808167 1.0 0.8157055362300466 26 Q9Y277,Q9UKU0,Q9NZ45,P45880,P16435,Q9NZZ3 6 +Allograft rejection 0.5642568078294303 1.1834899063212423 0.2366150444956343 1.0 0.8350618770698768 8 P08670,P10321,P08183 3 +Endothelin pathways 0.5419108031212412 1.0665653548867065 0.2861681519940089 1.0 0.9024138549652344 8 P42892,P16615 2 +Onecarbon metabolism and related pathways 0.4654865777399652 1.05755136225357 0.2902600266210915 1.0 0.9067045549883718 15 Q9HBU6 1 +Mitochondrial complex ii assembly 0.7704115989993946 1.0503209855072644 0.2935705599498588 1.0 0.91129194651102 3 Q99643 1 +Vitamin b12 metabolism 0.5508825568265987 1.0249773337082768 0.3053738827763368 1.0 0.9166128550045964 7 Q8WTV0 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.5666413671914832 1.0226558355843944 0.3064705997843391 1.0 0.9166128550045964 6 Q07812,Q07820,P49840,Q9BXK5 4 +Ccl18 signaling pathway 0.5157668026765895 1.0070989001857025 0.3138872496837661 1.0 0.9166128550045964 9 P07196,P08670,Q86UE4 3 +Mitochondrial complex i assembly model oxphos system 0.4239439589932108 1.005002281114163 0.3148957514558037 1.0 0.9166128550045964 31 O75306,O43676,P03886,Q9NPL8,Q9Y6M9,Q96CU9 6 +Eicosanoid metabolism via lipooxygenases lox 0.5601367148111177 0.9916441551765316 0.3213711417483185 1.0 0.9215788663184764 6 Q14914,P09960,O15254 3 +Vitamin b12 disorders 0.6293920061966835 0.9667896261975408 0.3336492114178013 1.0 0.9424404265640264 4 Q96EY8 1 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.7442739396932372 0.95414348846913 0.3400110153714646 1.0 0.955880024346193 3 P31751 1 +Head and neck squamous cell carcinoma 0.4578817303180408 0.9214078170882511 0.3568375490538735 1.0 0.971119539890907 13 P62942,P31751 2 +Prostaglandin and leukotriene metabolism in senescence 0.8638906152890005 0.9075111230701552 0.3641365701285513 1.0 0.9734806386140732 2 P09960 1 +Riboflavin and coq disorders 0.5401884828654848 0.8968556352576752 0.369795956035285 1.0 0.9795483990979106 6 Q8NI60,Q16134 2 +Nad biosynthetic pathways 0.726111186305662 0.8880970565047498 0.3744885458620826 1.0 0.9832386490475824 3 P43490 1 +Nad metabolism 0.726111186305662 0.8880970565047498 0.3744885458620826 1.0 0.9832386490475824 3 P43490 1 +Amyotrophic lateral sclerosis als 0.4562702414565514 0.8750395458048743 0.3815523888095371 1.0 0.9973913321512462 12 Q9BUN8,P07196,O96008 3 +Copper homeostasis 0.5324137071391484 0.8600954431369354 0.3897364329226422 1.0 1.0 6 Q9Y6N1,P05067 2 +Sarscov2 and covid19 pathway 0.7063272171156352 0.8171080815116555 0.4138666649730189 1.0 1.0 3 Q8WTV0 1 +Ketogenesis and ketolysis 0.5038772735070761 0.7917203299575717 0.4285237655282696 1.0 1.0 7 P23786,O43772,P53985,P35610 4 +Congenital generalized lipodystrophy cgl 0.695057506994074 0.7772022767653322 0.4370394391757046 1.0 1.0 3 P31751,P62993 2 +Hostpathogen interaction of human coronaviruses mapk signaling 0.4858254409820078 0.7744121751629018 0.4386870860020231 1.0 1.0 8 Q15418 1 +Methionine de novo and salvage pathway 0.4833146865056401 0.7614793772182746 0.4463707920701283 1.0 1.0 8 Q13126 1 +Vitamin dsensitive calcium signaling in depression 0.5086049224444966 0.7484908658229047 0.4541641325614995 1.0 1.0 6 Q8NB78,P20020 2 +Folate metabolism 0.4174819287532207 0.7417085332937206 0.4582639485312234 1.0 1.0 15 Q8WTV0 1 +Cancer immunotherapy by pd1 blockade 0.6837384384462262 0.7375710030507043 0.4607751815651948 1.0 1.0 3 P04439 1 +Eicosanoid metabolism via cyclooxygenases cox 0.5042285759263531 0.7281777359373407 0.4665047928678527 1.0 1.0 6 Q14914,O15254 2 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.4707448741781778 0.697069212509449 0.4857594804269884 1.0 1.0 8 P31943 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.4390949107515695 0.6605620083538631 0.5088932399653472 1.0 1.0 10 P31751 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.4188022795922708 0.6474294686238797 0.5173540288755818 1.0 1.0 12 P13674,Q9NVV0,Q5JRA6,O75718,Q96AY3 5 +Inclusion body myositis 0.7737725295214458 0.6038535471473966 0.5459410151189281 1.0 1.0 2 P05067 1 +Fatty acid betaoxidation 0.3619209916734722 0.5827472634722889 0.560063451068217 1.0 1.0 21 P35610,Q9UKU0,P49748,P23786 4 +Hostpathogen interaction of human coronaviruses apoptosis 0.6375505129002152 0.5816658608883973 0.5607917710892687 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0.3486051672842278 0.447870851607176 0.654246405920599 1.0 1.0 19 Q03518,P31943,P35637 3 +Apoptosis modulation and signaling 0.3709519000916823 0.4447908261385677 0.6564709246435747 1.0 1.0 15 Q9NR28,Q07820,Q13546,O95831 4 +Proteasome degradation 0.3528065166233665 0.4177084416761099 0.676160299518882 1.0 1.0 39 P49721,P48556,P28070,O00231,P20618,P28074,P28072,Q99436,P10321,P61289 10 +Cannabinoid receptor signaling 0.4330135960154467 0.4129115318686489 0.6796714318323502 1.0 1.0 6 Q8NCG7 1 +Pathways of nucleic acid metabolism and innate immune sensing 0.4429202252144097 0.3924816871739561 0.6947023396774643 1.0 1.0 5 O00584,Q7Z434 2 +Thermogenesis 0.3441016646496706 0.3848198320069692 0.700370904725085 1.0 1.0 29 P23786,Q9UKU0,P51812,P54646,Q15418 5 +Neuroinflammation 0.558284115635684 0.345705913845248 0.7295637393972849 1.0 1.0 3 Q16539,P00403 2 +Overview of nanoparticle effects 0.6821006836544335 0.3444047087538468 0.7305419481625992 1.0 1.0 2 P09601 1 +Mirna biogenesis 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0.616842759477947 0.2057818092376495 0.8369613512236294 1.0 1.0 2 Q99829 1 +Sulfation biotransformation reaction 0.4982903326080296 0.2055527724133241 0.8371402717863301 1.0 1.0 3 P00390,P11413 2 +Fluoropyrimidine activity 0.3418255665997561 0.2014060885878381 0.8403810547558099 1.0 1.0 11 P00374 1 +Kit receptor signaling pathway 0.3197381049944851 0.170039476174161 0.8649790911894937 1.0 1.0 16 P62993,P40763,Q15418,P51812 4 +Nocgmppkg mediated neuroprotection 0.3590300640610418 0.1417962143432654 0.8872409743723082 1.0 1.0 6 P30536 1 +Mthfr deficiency 0.3650667278693814 0.1385946847036122 0.8897704437652325 1.0 1.0 5 P35790 1 +Nitric oxide metabolism in cystic fibrosis 0.3805970149253661 0.1254199942432958 0.9001910599777854 1.0 1.0 4 Q99873,O14744,Q86X55 3 +1q211 copy number variation syndrome 0.3384264683559201 0.1215491388356778 0.9032560960293368 1.0 1.0 9 Q9NPH0 1 +Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.4460028254466457 0.1170167843098226 0.9068467529014408 1.0 1.0 3 P09601 1 +Genes related to primary cilium development based on crispr 0.3190261423610722 0.115883058023156 0.90774522296536 1.0 1.0 13 Q96J42,Q10713,O95684 3 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.3561430793156956 0.1155562560960337 0.9080042331498716 1.0 1.0 5 P09601,P48507,Q16539,P07099 4 +Transsulfuration and onecarbon metabolism 0.2968220022789341 0.1146491199996817 0.90872324424511 1.0 1.0 19 O43175 1 +Camkk2 pathway 0.3407829989363297 0.1113401501442559 0.9113466181051773 1.0 1.0 8 O76024 1 +Apoptosis 0.3371731008717283 0.098708757536258 0.921369515318863 1.0 1.0 8 Q07812,P04637,Q9NR28,O00273,Q9NRZ9,Q07820,Q13546 7 +Cellular proteostasis 0.3644278606965117 0.0949713556294439 0.9243375789532442 1.0 1.0 4 Q9UHV9,O60925,P61758 3 +Mirna regulation of p53 pathway in prostate cancer 0.4233758159776303 0.0887266206295278 0.9292991757641432 1.0 1.0 3 Q07812,O96017 2 +Mammary gland development pathway involution stage 4 of 4 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0000000000000000000000000000000000000000..e643175c0ce98bd86425046e9243e0fb6420d11a --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical tgfb signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir5093p alteration of yap1ecm axis", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCD1", "ABCD3", "ABCF1", "ABCF2", "ABHD16A", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA6", "AP1G1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATG9A", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "B3GALT6", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BLVRA", "BLVRB", "BRD4", "BRIX1", "BRK1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP170", "CEP44", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1L", "CHD4", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COQ9", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPAGT1", "DPF2", "DPM1", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMC10", "EMD", "EML4", "ENAH", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC2", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAM120A", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GID8", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2I", "GTPBP4", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMNA", "LMNB1", "LMNB2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM2", "LSM4", "LSS", "LTA4H", "LUC7L", "LYN", "LYRM7", "LZTFL1", "MACF1", "MAD2L1", "MAGT1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBNL1", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFN2", "MGMT", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MMADHC", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR12", "MTMR2", "MTOR", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NAT14", "NBN", "NCAPG", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NLRX1", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NPC2", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", 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"POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBMX", "RBP1", "RBPMS", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIF1", "RING1", "RIPK1", "RNASEH2A", "RNASET2", "RNF40", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", 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"TECR", "TEDC1", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLN1", "TMED10", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP3A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIP13", "TRMT2A", "TSC2", "TSC22D3", "TSG101", "TSPO", "TTC19", "TTC26", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXN2", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2J1", "UBE2L3", "UBE2N", "UBIAD1", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UPF1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", 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sha256:58e80d09016299ed15c1768054516902ecd1d5c8b7712b327c0f478bdab45e3c +size 143763 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b8d2aa1de38bedb271576fdb7ca72f564038aaaa --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dfcc5a86e0bd51563597c749f26d9a59dc318c5bb63cb214c5a069199b1a9ad8 +size 73090 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..06483991b6f8fc8b55fb50cf6b1cfcba67d27ac0 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 48 100 4.105191097185489 4.03980784993152e-05 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 2.8222666774594697e-10 0.0006250933311618 7.348969636463593e-05 1.5938843806800965e-06 5.451595456924306e-16 +mitochondria 9 12 2.4352897966831515 0.0148798672543593 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0064033235801391 0.0619434524836269 0.0069232563631819 0.0379575415698398 0.0027630263410089 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fef3ba445c7d0065aed80915ade427cefcce4ec7 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 97.3529411764706 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a1b337319cde682d83ae8cad812430d61529b4de --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..89de4ae3bddab067ed260d576e9f290307a8b275 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.5760969296253438 4.105191097185489 4.03980784993152e-05 0.0006865454266688 0.0006867673344883 100 Q15125,P48449,Q16850,Q969V3,Q07065,Q9BRK0,Q8NF37,Q00765,Q9NPA0,Q15363,O95674,Q96A33,O95470,Q15392,O60499,O75340,O00767,Q8N4V1,O00400,Q9NTJ5,Q9H6H4,O15269,Q6NUK4,Q9NQC3,Q14739,Q5HYI8,Q969Q5,O14735,Q9Y487,Q96N66,Q9BVG9,P51572,O15173,P49755,Q9P2W9,O75845,P27824,Q06136,Q9Y3E0,Q9NR31,O96005,Q8NHH9,P46977,P61026,Q15041,Q9Y5M8,O75915,O00264 48 +mitochondria 0.7218034500597832 2.4352897966831515 0.0148798672543593 0.2249739305269138 0.0843192477747027 12 Q96H55,Q9NR31,Q9Y277,Q9NVH1,Q15388,O94826,Q969Q5,P45880,P21796 9 +vesicles 0.3630099052477765 0.6962377243148467 0.4862799662788293 0.9999879121088489 0.7026024913201654 182 P56589,Q15125,P48449,Q8IXU6,Q969V3,P21281,Q8NF37,Q5VW38,Q15363,O95674,O14653,O95470,P31751,Q15907,O14964,Q15392,O60499,Q96L92,P51798,O43752,Q8NBN3,Q9UI14,O00400,P05023,P11279,O15269,O95249,Q93050,Q8IZA0,O14735,Q5HYI8,Q10713,Q9H2V7,P30825,Q9H2J7,O15173,O75845,P53985,Q9Y3E0,O96005,P11166,O00264 42 +golgi 0.3280322217925023 0.4182795714871656 0.6757427238941207 0.999999995156878 0.7026024913201654 64 Q8IXU6,Q9H8Y8,Q6RW13,Q5VW38,O14653,Q15907,Q8NBN3,Q9UI14,Q9NTJ5,Q9Y371,Q8IZA0,Q9Y6B6,O14735,Q9Y487,Q15904,P49755,Q9NR31,Q9Y3E0,O15258,P61026 20 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..83a29f24ca3127aa7f4c363ef60e5e26a005d8da --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AGPAT2", "AGTRAP", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALDH16A1", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC4", "ANKRD17", "ANKRD54", "ANXA11", "AP2B1", "AP2S1", "APPL1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATL2", "ATL3", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1B", "BUD23", "BYSL", "C8orf33", "CAD", "CALD1", "CALM3", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2BP2", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDS2", "CEP170", "CETN2", "CHEK2", "CHMP1A", "CHMP3", "CHMP4B", "CHMP7", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTC", "CNN2", "COIL", "COMMD2", "COMMD4", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CUTC", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL2", "EBNA1BP2", "EBP", "EDC3", "EDC4", "EDF1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMG1", "ENO1", "ENY2", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FAM50A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", 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"MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MBOAT7", "MDH1", "MECP2", "MED14", "MED17", "MED21", "MED24", "MED4", "METAP2", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVK", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO6", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP1", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAK1", "PAK2", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIN4", "PIP4K2C", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", 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"SPOUT1", "SPTLC1", "SPTLC2", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIM2", "STIP1", "STK26", "STK4", "STT3A", "STX10", "STX12", "STX18", "STX5", "STX6", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TAOK2", "TARDBP", "TCOF1", "TFRC", "TIA1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOLLIP", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM28", "TRIR", "TRMT1L", "TSG101", "TSR1", "TTK", "TUBB4B", "TUBG1", "U2AF2", "U2SURP", "UBA1", "UBE2M", "UBTF", "UFC1", "UGDH", "ULK3", "UPF1", "USP10", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS18", "VPS25", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS4A", "VRK2", "VRK3", "WAPL", "WASF2", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO5", "XPOT", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["AGTRAP", "AKT2", "ARL6IP1", "ARL6IP5", "ATL2", "ATP1A1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "BCAP31", "CANX", "CCDC47", "CDIPT", "CDS2", "CKAP4", "CLCN7", "CLPTM1", "CYP51A1", "DHCR24", "DNAJC11", "EBP", "EMC7", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GPR107", "HGS", "KDSR", "KIAA0319L", "LAMP1", "LBR", "LPCAT1", "LSS", "MBOAT7", "MMGT1", "MYO19", "NCLN", "PDCD6", "PEX3", "PGRMC1", "PGRMC2", "PMPCA", "PTDSS2", "RAB10", "RAB11B", "RAB24", "RABAC1", "RABL3", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RTN4", "SACM1L", "SAR1A", "SAR1B", "SC5D", "SCD", "SGPL1", "SH3GLB1", "SLC16A1", "SLC2A1", "SLC33A1", "SLC35F2", "SLC6A15", "SLC7A1", "SNX27", "SPNS1", "SPTLC1", "SRPRB", "STT3A", "STX10", "STX18", "STX6", "TMED10", "TMED2", "TMEM87A", "TOMM20", "TOMM70", "VDAC1", "VDAC2", "VDAC3"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json 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2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0579592766667772 0.0619434524836269 0.1203280145079081 0.0379575415698398 0.0027630263410089 +oxidase 9 14 2.246188743308128 0.0246919209529385 5.111650485436893 13.890776699029129 1.1786899361665428 0.2351652471103072 2.6295852591466065 1.831549924215542 1.2715889014379809 0.2754701040210626 0.0783255539454932 1.0 0.2780273254227372 0.0444854600227105 0.07392944267488 +acyltransferase 12 21 2.2379691303025906 0.0252230682674865 5.550970873786408 17.609223300970875 0.8395368249042097 0.3495065414698917 3.0409541216574527 2.8086572783837886 1.152491475155923 0.3107783941454108 0.000247233012017 0.0179094063189584 0.0636449972198752 0.0180565405233996 0.000798592209508 +SNARE protein 4 14 2.1138746270710835 0.0345259768696448 4.660194174757281 11.12378640776699 0.9288896561072936 0.3201954718639376 2.5506648592929815 2.745113440103806 1.1546709449924732 0.3042666981599379 0.0110460269750891 1.0 0.2489059409173845 0.0319451393300601 0.0119362160344991 +oxidoreductase 13 42 2.095248891562508 0.0361488731313741 12.558252427184469 43.60436893203884 0.9664652969079414 0.3656199292680728 5.072676172192643 3.8442089013841825 1.3118377214144643 0.3470065139863294 0.0023967036641984 0.0011734825476199 0.0023682370591 0.007976907507528 0.0001834862218712 +transmembrane signal receptor 5 6 2.00479111732408 0.0449853825574586 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.5358463308775576 1.0 0.2280025569563264 0.65511488808051 0.6593661810718379 +amino acid transporter 3 5 2.003265496682932 0.0451487988351722 1.9951456310679612 4.257281553398058 0.7191216814048915 0.3104355279029646 1.1762106872211882 0.8905220397339731 1.285467922271347 0.3110567625654792 0.0425293714029277 1.0 0.0049445172385496 0.0276231155809849 0.0140126286640228 +membrane trafficking regulatory protein 8 20 1.982061857115064 0.0474723179027261 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0222134156482445 0.2298835505782255 0.0150469902773183 0.0385372375494843 0.0423415641222214 +serine protease 7 20 1.9718514481523055 0.0486265671889531 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0001037902129732 0.2145132052110039 0.0013159065844779 0.0001580597168237 0.0022658484440293 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..efb998dc892a9f056b593c0e25aef0152b3f0c79 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 158, + "title": "Average number of proteins per term", + "value": 13.91139240506329 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d0f194ff894724e943242b65b145155161cc06d9 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7acb019ee2f025ecc8920720d73d7782e1b9bfae --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,42 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.5995525004926051 3.0326472991146978 0.0024241875374459 0.3185188179104303 0.3175613057977042 61 Q9Y619,Q92544,P62072,O60830,Q15012,Q8N8Q8,Q567V2,Q9Y584,Q99805,Q9H2V7,O43772,Q9HD45,Q99595,P53985,Q15070,P54105,Q9H2D1,Q8NFH4,Q9NR77 19 +secondary carrier transporter 0.7609924605081677 2.868157994385142 0.0041286930178807 0.4798738274395391 0.3175613057977042 15 Q9UBX3,Q96H78,Q8TB61,O00400,Q9BQT8,Q96ES6 6 +metalloprotease 0.6223220737332609 2.502837010912511 0.0123202266893942 0.8589564367175705 0.3175613057977042 28 O43847,P42892,Q10713,O75844,Q7Z2K6,P22695,P55786,Q9NZ08,Q9UIQ6 9 +oxygenase 0.7988479544938409 2.482556082586907 0.0130443532533486 0.8743893359573198 0.3175613057977042 9 Q16850,Q14534,P30519,Q6UW02,Q9BV57 5 +phospholipase 0.7642190414658662 2.4486536825149967 0.0143391243991439 0.8979183043690864 0.3175613057977042 10 Q8NHP8,Q8IV08,Q8N2A8 3 +protein modifying enzyme 0.6031186322510657 2.3562187170009854 0.0184620438375657 0.9473593118554746 0.3175613057977042 24 O60725,Q6P2P2,Q92791,O75718,Q86YN1,P51812,Q12797,Q9UMR5,Q15418,P50897 10 +mitochondrial carrier protein 0.7914072229140715 2.3213472887077997 0.0202681079485405 0.9606499973697296 0.3175613057977042 8 Q9NZJ7,Q9Y6C9,Q70HW3,Q6NUK1,Q9HC21,P16260,Q9BSK2 7 +oxidase 0.6649862197804959 2.2461887433081276 0.0246919209529385 0.9807510149219856 0.3175613057977042 14 Q8NB78,Q6ZRP7,P36551,Q15800,P13073,O75845,O14548,P20674,P14406 9 +acyltransferase 0.5860033088980565 2.2379691303025906 0.0252230682674865 0.9823384672617224 0.3175613057977042 21 P49356,Q86SQ9,Q9BWD1,P23786,P49354,Q8NF37,Q8NCC3,P35610,Q92604,Q9NUQ2,P50416,O15228 12 +G-protein coupled receptor 0.9294687698581632 2.1953521941039456 0.0281383435516953 0.9889972112821398 0.3175613057977042 4 Q5VW38,Q8NBN3 2 +SNARE protein 0.6424767492283139 2.1138746270710835 0.0345259768696448 0.9961183736321868 0.3340433746023741 14 O95249,O43752,Q9P2W9,O60499 4 +oxidoreductase 0.5498636898546794 2.0952488915625076 0.0361488731313741 0.997024406556344 0.3340433746023741 42 O75306,O43676,Q15067,Q86Y39,Q8N0U8,O15254,Q8N4Q0,O43169,O14949,O95831,Q9Y6M9,Q16134,P16435 13 +transmembrane signal receptor 0.7762912258867569 2.00479111732408 0.0449853825574586 0.9993056427209156 0.3340433746023741 6 O00264,O15173,Q8WUJ1,Q9UMX5,Q99720 5 +amino acid transporter 0.8112175828267632 2.003265496682932 0.0451487988351722 0.999324165428424 0.3340433746023741 5 O60831,O14925,P30825 3 +membrane trafficking regulatory protein 0.5490690707525762 1.982061857115064 0.0474723179027261 0.999540101779992 0.3340433746023741 20 Q14108,O00560,P50542,P11279,O43760,O43731,Q8WTV0,P24390 8 +serine protease 0.5476271743783292 1.9718514481523055 0.0486265671889531 0.9996202820851 0.3340433746023741 20 Q9H3G5,P42785,Q9HB40,P67812,P10619,O14773,Q16740 7 +ATP synthase 0.5186484405359995 1.7599325905611305 0.0784192367068725 0.9999975095527932 0.3887019601163649 21 P21281,P24539,O75964,Q93050,P00846,P56385,Q9Y487 7 +calmodulin-related 0.5644367880158799 1.5849372940735924 0.1129805820584093 0.9999999940648172 0.426513731977932 13 Q02818,Q14257,O43852,P41208,P80303 5 +voltage-gated ion channel 0.9079888094497872 1.565056283187722 0.1175697128585482 0.9999999973848048 0.426513731977932 3 P45880,P21796 2 +ion channel 0.6586118952015936 1.5599318960826123 0.1187759759938544 0.9999999978931196 0.426513731977932 7 P51798,Q9C0H2,Q9Y696,P51790 4 +tubulin 0.6273349937733487 1.5107813116900932 0.1308441776533413 0.9999999997615332 0.4594084459828428 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +glycosidase 0.6933861001563195 1.4854020065618667 0.1374373644549278 0.9999999999283986 0.4720674692147521 5 Q9BTY2,P06865 2 +transfer/carrier protein 0.5750712783774637 1.4338573493468358 0.1516129752041428 0.9999999999947776 0.4888744914745831 10 P12236,P12235,P17900,Q9Y5M8,P05141 5 +kinase 0.4614386749962994 1.3361408990562875 0.1815032241111311 0.999999999999982 0.5488782000493744 21 Q9HBU6,Q9BRR6,P52789 3 +esterase 0.5215199719635002 1.0385555706811966 0.2990114779347443 1.0 0.6780078917757532 9 Q969T7 1 +primary active transporter 0.4245432281218804 1.035911119923131 0.3002436093824623 1.0 0.6780078917757532 24 P98194,Q9BUN8,Q9H2J7,O75381,P05023,Q9NS69,O96008,P16615,O60888,Q9Y5J6,Q8N4H5 11 +glycosyltransferase 0.4190764438178986 0.987738500903866 0.3232807335228329 1.0 0.7034592114862667 25 Q8N4A0,P46977,Q8NBN7,Q10472,Q9BV10,Q9BT22 6 +transferase 0.4176111374195206 0.9538826098771148 0.3401430670476872 1.0 0.7034592114862667 36 Q9BVG9,Q9Y5Z9,Q8NCH0,O95674,Q7LGA3,Q8NBI6,O43505,Q9NRB3,O14735,P43490,Q9C0D9 11 +ATP-binding cassette (ABC) transporter 0.491358999765399 0.8739131510146135 0.3821655522677227 1.0 0.7099529682640637 9 O75027,P08183 2 +methyltransferase 0.4278796504258615 0.8546037012100763 0.3927705779060697 1.0 0.7099529682640637 16 Q9BV86 1 +galactosidase 0.8095090118085648 0.7200374876052655 0.4715019146569323 1.0 0.744973025157953 2 P06280 1 +lyase 0.4045829405476158 0.6578914397516804 0.5106078916348697 1.0 0.7670681135617815 15 Q9BU89,Q9UHG3,Q8NBM8 3 +major histocompatibility complex protein 0.7719080174021171 0.5979823540065278 0.5498517073989238 1.0 0.7897869979002723 2 P10321 1 +protease 0.371216045586215 0.5689546212886836 0.5693869359228385 1.0 0.7999832154826547 37 Q15005,Q9BT78,P49721,P48556,P28070,P61009,P60900,P20618,P28074,P28072,Q99436,O43242 12 +actin and actin related protein 0.460031104199065 0.4584682371096883 0.6466160771696798 1.0 0.865807967735673 5 O96019,Q9NZ32,P61160,P61163 4 +kinase modulator 0.4558084250934788 0.4419208567098819 0.6585464774859258 1.0 0.8743726339729098 5 P10644 1 +reductase 0.3343499030785515 0.2947523977162797 0.7681830327470767 1.0 0.905768053537598 32 Q9H7Z7,Q9UDW1,P31350,Q14914,Q7LG56,Q14739,Q15392,P00374 8 +guanyl-nucleotide exchange factor 0.3926047838632996 0.2549607074260608 0.7987534474158169 1.0 0.927963563909552 6 Q9Y4G8 1 +heterotrimeric G-protein 0.3661337446765937 0.1641371950802117 0.8696231414324567 1.0 0.9568997600670558 6 Q8NHH9 1 +phosphatase 0.3047264211424215 0.1102151234654193 0.9122387685529108 1.0 0.980501533546666 17 Q9H773,Q9NPH0 2 +cytoskeletal protein 0.3111387678904759 0.0167668876251362 0.986622586029557 1.0 1.0 6 Q14141,Q9NVA2,Q16181,Q15019,P27105 5 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0d4900d7754c2892f2ac0ee346ed19a121fef154 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT2", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "ANAPC1", "ANAPC7", "ANKFY1", "ANKRD17", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP18", "ARHGDIA", "ARIH1", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRIX1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CDS2", "CEBPZ", "CEP170", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNOT7", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF13", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC10", "EMC2", "EMG1", "ENAH", "ENO1", "ENY2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GID8", "GINS1", "GINS2", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUS1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "ISCU", "ISOC1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KCMF1", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LYRM7", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFSD3", "MFSD5", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "ND1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NENF", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX13", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAD9A", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RING1", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNPS1", "ROCK1", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", 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sha256:1e03fd6f133fef72c30fd3e15ab06c7cb3dd40324fae70dc5c92184ff4b11779 +size 133223 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0096c171aba52ad1e6327e16f2ed685e8cf1ae72 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bfa65216a437ab0c4fdb0e8828e0b031d9ae9ed5e4850c94a88f23c3c24e9fb +size 215510 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d19cdbb784b81a3636511216484522e082c2b259 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC25 family of mitochondrial transporters 17 23 3.255855026330845 0.0011305145969235 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.221625459493401e-05 0.1665759675679584 0.0507931717892238 2.159661966497117e-06 9.150174799393413e-08 +SLC superfamily of solute carriers 31 48 3.0943971800893064 0.0019721327856818 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.0013492751113723 0.2242958901844974 0.0331633114708278 0.0004582652486696 6.918699052675977e-05 +Mitochondrial nucleotide transporter subfamily 9 10 2.547393144127301 0.0108531085754539 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0008878528391423 0.0711332726649859 0.1375212864755611 0.000366006536683 4.367834065541858e-05 +Transporter 89 201 2.442720752608159 0.0145770115540759 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 7.261815666934868e-07 0.0311256034896837 7.549112491377193e-05 2.133036899138077e-06 1.6699141293262094e-12 +Receptor 10 28 2.301890363691649 0.0213413557823003 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0050094406148847 0.4077336964203657 0.2789376381858768 0.0040448950832466 0.0136443970185141 +Oxidase 13 21 2.182289409981105 0.0290881800927123 6.703883495145631 19.237864077669904 1.0247065178117305 0.263154064152295 3.1321515397534676 1.9967748999180144 1.3264616190823058 0.2799417791483025 0.003007131926098 0.1499686155438198 0.0412914524019695 0.0078094686864188 0.0001380057592112 +Phospholipase 1 5 2.172329423411479 0.0298308242202633 0.9150485436893204 3.7305825242718447 0.7966129457254134 0.3188877353015109 0.8533581565055661 1.071582012810982 1.2006971708387306 0.2905331526823088 0.1333518813406911 0.0981765691424607 0.1871299927573601 0.0901924811619011 0.2715157705871365 +Lipase 1 7 2.152070121771047 0.0313918319534594 1.3980582524271843 5.075242718446602 -0.1568413865531176 0.2870211072037147 0.9252636026942443 1.467005631758797 1.4600847921937092 0.2541679924186693 0.1874080902331407 0.1201219647894398 0.2263045436956677 0.1292409073430241 0.3621483333283614 +Signaling 9 17 2.1361150354513505 0.0326700385230009 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.280983955427364 1.0 0.5815024054643041 0.3571368988977866 0.4256782528579432 +SNARE protein 4 14 2.1138746270710835 0.0345259768696448 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 0.0085600651605588 1.0 0.2339121686337894 0.0264830942684438 0.008785557350241 +Oxidoreductase 34 119 2.087908274490066 0.0368061096342082 26.983009708737864 113.91747572815534 0.6392672411957 0.4324241122550336 10.483097938966514 7.235161275092307 1.3581321831066435 0.3819609334162012 4.548326166766625e-07 0.0195472198633937 0.0046369105133191 3.308365256960079e-06 1.2245220494390508e-10 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..02046091362475d75465f422f2d95d3341822250 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 2057, + "title": "Average number of proteins per term", + "value": 3.1385512882839084 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..37545dcddb50995d9489f2ceba5c1fdae953d096 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8803eb173bfaa1ae9718be186ef9be55855f92d7 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,67 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC25 family of mitochondrial transporters 0.7406716587347785 3.2558550263308454 0.0011305145969235 0.9023908466335054 0.2857510111537066 23 Q00325,P12236,Q9NZJ7,Q9UBX3,Q96H78,Q70HW3,Q9Y6C9,Q9BQT8,Q9Y619,Q9H2D1,Q9HC21,O43772,P12235,Q6NUK1,P16260,Q9BSK2,P05141 17 +SLC superfamily of solute carriers 0.6615545595276019 3.0943971800893064 0.0019721327856818 0.982762750360674 0.2857510111537066 48 Q8IXU6,Q8TB61,Q70HW3,Q9Y619,Q9HC21,P05141,Q00325,O00400,O14975,Q9Y6C9,Q9Y6M7,O43808,Q9HC07,Q9H2V7,P30825,Q96H78,Q9H2J7,Q9BQT8,O43772,P08195,P16260,P53985,Q9BSK2,P12236,Q96NB2,Q9NZJ7,Q9UBX3,Q9H2D1,P12235,Q6NUK1,P11166 31 +Mitochondrial nucleotide transporter subfamily 0.7838006230529708 2.547393144127301 0.0108531085754539 0.9999999998215788 0.2857510111537066 10 P12236,Q70HW3,Q9H2D1,P12235,Q6NUK1,Q9HC21,P16260,Q9BSK2,P05141 9 +Transporter 0.5045786126800439 2.442720752608159 0.0145770115540759 0.9999999999999238 0.2857510111537066 201 Q00765,Q70HW3,Q9HC21,P17900,P00846,P24390,Q15012,O00400,O00560,O14975,Q9Y6C9,Q9Y584,O43731,Q9BQE5,Q9H2V7,P30825,Q96H78,P51572,P49755,O75027,Q9HD45,Q9P2W9,Q15070,Q8N1F7,Q9UBX3,Q9H2D1,Q6NUK1,P33897,O75947,Q12769,Q8TB61,Q15363,Q9Y619,P13473,P50542,P05141,O60499,Q00325,Q9H6H4,O95249,Q6NUK4,P20020,O43808,Q9HC07,Q99805,Q9BQT8,P08195,P16260,Q12907,O95202,Q9H270,P54105,Q9BVK6,P12235,P08183,Q96ES6,Q9NZZ3,Q8IXU6,Q03518,O43760,O43752,Q93050,Q9Y6M7,Q9Y487,Q9Y3B3,P16615,Q9BSK2,Q9NZJ7,Q99523,Q8NFH4,P98194,P21281,Q9BRK0,Q92544,O14653,Q9Y5J6,Q9UI14,P05023,P11279,O96008,P24539,Q9H2J7,O43772,P53985,P56385,P12236,Q96NB2,Q8N2H4,P11166 89 +Receptor 0.5938827286934784 2.301890363691649 0.0213413557823003 1.0 0.2857510111537066 28 P57105,Q14108,Q9BUN8,Q9Y639,Q13641,Q567V2,Q9UQB8,Q9NR77,Q8WTV0,A6NIH7 10 +Oxidase 0.5779795161402429 2.182289409981105 0.0290881800927123 1.0 0.2857510111537066 21 Q15067,P36551,Q6ZRP7,O15254,P49748,O15260,O43169,Q15800,O75845,O14548,P20674,Q709F0,P14406 13 +Phospholipase 0.8509513296556687 2.172329423411479 0.0298308242202633 1.0 0.2857510111537066 5 Q8NCC3 1 +Lipase 0.782922910278121 2.152070121771047 0.0313918319534594 1.0 0.2857510111537066 7 Q8NCC3 1 +Signaling 0.6105962406371467 2.1361150354513505 0.0326700385230009 1.0 0.2857510111537066 17 Q5JRA6,Q99627,O15173,P42166,Q8WUJ1,Q9UHD1,Q96PC5,P43490,O00264 9 +SNARE protein 0.6424767492283139 2.1138746270710835 0.0345259768696448 1.0 0.2857510111537066 14 O95249,O43752,Q9P2W9,O60499 4 +Oxidoreductase 0.4222757693923626 2.087908274490066 0.0368061096342082 1.0 0.2857510111537066 119 Q16850,P03886,Q8N0U8,O15260,P30837,O43169,Q96CU9,Q15392,O75306,Q13423,P31350,P49748,Q9NZ01,Q99757,O95831,Q9H9P8,Q9BV57,Q14739,Q15800,P14406,P00374,Q14534,Q15067,Q9UDW1,O15254,O75845,Q9Y6M9,Q9UBM7,Q9H7Z7,Q8N4Q0,Q14914,O43175,Q7LG56,Q16134 34 +Mitochondrial amino acid transporter subfamily 0.7478734613927616 1.875906299417483 0.0606681475008707 1.0 0.3060746202789437 6 Q96H78,Q9Y619 2 +Ion channel 0.6530574239410312 1.8653628883482565 0.062130555590012 1.0 0.3060746202789437 10 P51798,Q9NVV0,Q4KMQ2,Q9Y696,Q9C0H2,P51790 6 +Calcium-binding protein 0.5259823418921135 1.8172715305662137 0.0691755469446173 1.0 0.311700718346786 20 Q02818,Q14257,O43852,P41208,P80303,Q8IYU8,P43307 7 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.821549919822895 1.7634460846417972 0.0778252830164227 1.0 0.3183873552236551 4 Q9UBX3 1 +Oxygenase 0.7205785927620832 1.7505433298341824 0.0800246042074233 1.0 0.3215050993255268 6 Q16850 1 +P-type ATPases 0.6966179646042732 1.6393008359060526 0.1011506220419891 1.0 0.350926962059401 6 P05023,P98194,P16615 3 +F-type ATPase 0.6523985193188168 1.6388708984895977 0.1012401496525228 1.0 0.350926962059401 8 P00846,P56385,P24539 3 +Intracellular calcium-sensing protein 0.5312890344432658 1.6159735598615212 0.1061000298586232 1.0 0.3537240865789107 17 Q02818,Q14257,O43852,P41208,P80303,Q8IYU8 6 +Calmodulin 0.5312890344432658 1.6159735598615212 0.1061000298586232 1.0 0.3537240865789107 17 Q02818,Q14257,O43852,P41208,P80303,Q8IYU8 6 +Glycosyltransferase 0.5076266143379186 1.6012395441149183 0.1093238734359396 1.0 0.3580879102830061 19 Q8N4A0,P46977,Q10472,Q9BV10,Q9BT22 5 +Metalloprotease 0.4921005024766358 1.58952865203878 0.1119410906535287 1.0 0.3614800996456964 39 O43847,P42892,Q10713,O75844,Q7Z2K6,P22695,P55786,Q9NZ08,Q9UIQ6 9 +Esterase 0.5704746361972488 1.570786763027893 0.1162321877659298 1.0 0.3679711323843039 12 Q9UMR5,P50897 2 +Reductase 0.5132735256038652 1.5645105166216726 0.1176977251736011 1.0 0.3679711323843039 18 Q9H7Z7,Q9UDW1,P31350,Q7LG56,Q14739,Q15392,P00374 7 +F-type and V-type ATPases 0.5325405203114804 1.5573309604756278 0.1193919283359115 1.0 0.3709806594969335 16 P21281,P24539,Q93050,P00846,P56385,Q9Y487 6 +Tubulin 0.6273349937733487 1.5107813116900932 0.1308441776533413 1.0 0.3895028559087165 8 Q9BUF5,P68371,P04350,P07437,Q9BVA1,Q13885,Q13509 7 +Methyltransferase 0.5244397993367652 1.4436008725036444 0.1488512793663798 1.0 0.412651053445611 15 Q9BV86,Q96FX7 2 +Membrane trafficking regulatory protein 0.4608286483740401 1.3315485574354442 0.1830085787388964 1.0 0.4567365748141145 21 O00560,P50542,P11279,P13473,O43760,O43731,P24390 7 +Acyltransferase 0.5208871203916953 1.2712574976905835 0.2036370574218957 1.0 0.4735463269019142 12 P49356,Q86SQ9,Q8NF37,Q9Y679 4 +Protease 0.3504129195608693 1.1828618618002382 0.2368638986812234 1.0 0.514048150692945 112 P42892,Q8NHP8,P10619,Q9NZ08,O43847,O75844,Q13510,Q10713,Q9H3G5,P42785,P49915,P55786,O14773,Q9UIQ6,Q5BJF2,Q9HB40,Q7Z2K6,P67812,P22695 19 +Extracellular structure 0.5595139239722627 1.1586903809663427 0.2465824130939027 1.0 0.522368716513036 8 Q92791,O75718,O43290,Q5KU26,Q32P28 5 +SLC35 family of nucleotide sugar transporters 0.9195152268489692 1.1080931635811904 0.2678215831263202 1.0 0.5432903962151373 2 Q8TB61 1 +Ca2+-ATPases 0.7824059682934262 1.0947993169510972 0.2736045657577444 1.0 0.5485424870991035 3 P98194,P16615 2 +Phosphatase inhibitor 0.6033885350280737 1.0790553846949804 0.2805630385603437 1.0 0.5559905301720877 5 Q99733,P55209 2 +ABCB subfamily 0.5950048173740222 1.041180661323509 0.2977917092388764 1.0 0.5789676668488868 5 O75027,P08183 2 +ATP-binding cassette transporter family 0.5308630612858494 0.9252014890696144 0.3548611090901055 1.0 0.6295442138967821 7 O75027,P08183 2 +RSK family 0.8564325668116795 0.8811951047550342 0.3782122283909155 1.0 0.6497884211388747 2 Q15418 1 +RSK subfamily 0.8564325668116795 0.8811951047550342 0.3782122283909155 1.0 0.6497884211388747 2 Q15418 1 +Chloride channel family 0.8415164698570392 0.8290866682633338 0.4070553670460555 1.0 0.6696458633099673 2 P51798 1 +Miscellaneous SLC25 mitochondrial transporters 0.8278433809819786 0.7820031723691799 0.4342127092189352 1.0 0.6967047916250777 2 Q9NZJ7 1 +V-type ATPase 0.4752582307628586 0.7201270003715081 0.4714468046847664 1.0 0.7247878006252351 8 Q93050,Q9Y487 2 +Na+/K+-ATPases 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 0.7673230559620697 3 P05026,P05023 2 +Phosphatase modulator 0.4599764040930771 0.5799010851017089 0.561981323950187 1.0 0.7853230865254991 7 Q99733,P55209 2 +CAMK group 0.4675128703639758 0.5613257717919526 0.5745754757969892 1.0 0.7912928366762683 6 O96017,P54646 2 +AGC group 0.4261796708736799 0.4754568129631048 0.6344614084378184 1.0 0.8254820475373766 8 P31751,Q15418,Q96S38 3 +Growth factor 0.4636027401332133 0.4725901011534558 0.6365056460720169 1.0 0.8265733042740775 5 Q96PC5 1 +Actin and actin related protein 0.460031104199065 0.4584682371096883 0.6466160771696798 1.0 0.8344349251806973 5 O96019,Q9NZ32,P61160,P61163 4 +PI3/PI4 kinase family 0.7224984462399066 0.4507098771326195 0.6521986626728618 1.0 0.8374361105605971 2 P42356 1 +Unclassified protein 0.3476449445748721 0.4412172652538688 0.659055715176168 1.0 0.8404696876115174 19 Q9HBU6,Q9BRR6 2 +ABCD subfamily of peroxisomal ABC transporters 0.6898694841516484 0.3637284176509114 0.7160608205750305 1.0 0.8649072859206328 2 P33897 1 +Major histocompatibility complex antigen 0.4669406349801029 0.3527190090850394 0.7242991069831979 1.0 0.866879091438353 4 Q9NX40 1 +GSK family 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 0.8786997772144642 2 P49840 1 +GSK subfamily 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 0.8786997772144642 2 P49840 1 +Protein methyltransferase 0.4049006767612036 0.3008097907972257 0.7635595420270405 1.0 0.8786997772144642 6 O96028 1 +Eraser 0.3987742728938315 0.2776987049329296 0.7812436548247967 1.0 0.8849635019796793 6 Q8IXJ6 1 +Dehydrogenase 0.3276131249051098 0.2750830136354258 0.7832524614995227 1.0 0.8849635019796793 55 O75306,Q13423,P03886,Q8N4Q0,Q14914,Q9NZ01,O43175,O95831,Q9H9P8,Q96CU9 10 +Extracellular matrix glycoprotein 0.4263059701492447 0.2330172960671349 0.8157479750931966 1.0 0.8950456729320679 4 Q9BXS5,Q96CW1,Q32P28 3 +CDK1 subfamily 0.6180857675574857 0.2080048073525915 0.8352252137260825 1.0 0.89927292678316 2 P06493 1 +Acetyltransferase 0.3023417107893524 0.1676686329796703 0.8668439740543845 1.0 0.90558560417972 21 P23786,Q9BWD1 2 +Heterotrimeric G-protein 0.3661337446765937 0.1641371950802117 0.8696231414324567 1.0 0.905731906372832 6 Q8NHH9 1 +Translation initiation factor 0.2991249985063514 0.1368307222187628 0.8911645992101209 1.0 0.9183553891505531 22 O75153 1 +Protein arginine methyltransferase 0.3805970149253661 0.1254199942432958 0.9001910599777854 1.0 0.9230772733670513 4 Q99873,O14744,Q86X55 3 +CDK4 subfamily 0.4698570540708618 0.0530885824348392 0.9576613285220812 1.0 0.9661154255860328 2 P11802 1 +PAKA subfamily 0.4425108763207075 0.0437649812142079 0.965091741267005 1.0 0.97313417244423 2 Q13153 1 +CK2 family 0.4117464263517845 0.0373331992025708 0.970219334800049 1.0 0.977825169859726 2 P67870 1 +mRNA polyadenylation factor 0.3142501555693788 0.0234652018735091 0.9812791957195572 1.0 0.9884874170397304 6 Q10570,Q16531,Q96GM8,O95453,Q12996 5 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..08aa00c2ce9df1c5aa0fa19f1bc0ca97a1a8f95b --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "25-hydroxycholesterol 7-alpha-hydroxylase", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S27", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 1", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl carrier protein, mitochondrial", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase family 16 member A1", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "Butyrophilin subfamily 2 member A1", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 12", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell cycle checkpoint control protein RAD9A", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA topoisomerase 3-alpha", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC2", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disks large-associated protein 4", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 2, cytoplasmic", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethanolaminephosphotransferase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FAD-dependent oxidoreductase domain-containing protein 2", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Graves disease carrier protein", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SMYD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KHS subfamily", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophosphatidylcholine acyltransferase 2", "Lysophospholipid acyltransferase 5", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosomal-associated transmembrane protein 4A", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Map kinase-activated protein kinase 2", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Metastasis-associated protein MTA3", "Methionine aminopeptidase 1", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitogen-activated protein kinase kinase kinase kinase 5", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Muscleblind-like protein 1", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 12", "Myotubularin-related protein 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N6-adenosine-methyltransferase non-catalytic subunit", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NLR family member X1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear envelope pore membrane protein POM 121C", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin GLE1", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OCIA domain-containing protein 2", "OTU domain-containing protein 4", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PI3/PI4 kinase family", "PIKK family", "PKA family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Paired amphipathic helix protein Sin3b", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Patatin-like phospholipase domain-containing protein 2", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase DDHD2", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein FAM177A1", "Protein FRG1", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO1 subfamily", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with multiple splicing", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "RSKL family", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Ral-B", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho GTPase-activating protein 18", "Rho-associated protein kinase 1", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosomal protein s6 kinase delta-1", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Selenocysteine lyase", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio1", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase tao2", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 1", "Sodium-dependent HCO3- transporters", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-10", "Syntaxin-12", "Syntaxin-17", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Tetratricopeptide repeat protein 28", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Torsin-3A", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 10", "Transcriptional activator protein Pur-alpha", "Transcriptional coactivator YAP1", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transmembrane protein 62", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Trypsin-3", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase lyn", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "UDP-glucose:glycoprotein glucosyltransferase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTU1", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-XIX", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 11 homolog", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger RNA-binding protein", "Zinc finger protein 148", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter 9", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCF1", "ABCF2", "ABHD12", "ABHD16A", "ABHD6", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "ANAPC1", "ANO6", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP18", "ARHGDIA", "ARIH1", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "B4GALT1", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRD4", "BRIX1", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC42", "CDC45", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CEBPZ", "CEP170", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ5", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF13", "DCAF8", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDHD2", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOLPP1", "DPAGT1", "DPF2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBP", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS1", "GINS2", "GLB1", "GLDC", "GLE1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LRRC47", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LTN1", "LYN", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MAT2A", "MBNL1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED21", "METAP1", "METTL14", "METTL7B", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS16", "MRPS18A", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "ND1", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NLRX1", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCIAD2", "OCRL", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAK1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA2", "PNPLA6", "PNPT1", "POGZ", "POLA2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PRSS3", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAD9A", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPMS", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "ROCK1", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIN3B", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TAOK2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM259", "TMEM38B", "TMEM62", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOP3A", "TOR1A", "TOR1B", "TOR3A", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSG101", "TST", "TTC28", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2L3", "UBE4B", "UBIAD1", "UCHL5", "UCK2", "UGCG", "UGGT1", "ULK3", "UNC119B", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS11", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WIZ", "WNK1", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YAP1", "YARS", "YARS2", "YEATS4", "YLPM1", "YME1L1", "YOD1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZNF148", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ACAD11", "ACADVL", "ACAT2", "ACOX1", "ACOX3", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ADI1", "ADPGK", "AIFM1", "AKT2", "ALDH1B1", "ALG1", "ALG12", "ANO6", "AP1M1", "AP2M1", "APOL2", "ASAH1", "ATL2", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5F1", "ATP5H", "ATP5I", "ATP6", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "AUP1", "BAIAP2", "BCAP31", "CALU", "CARM1", "CDK1", "CDK4", "CETN2", "CHEK2", "CHMP5", "CHORDC1", "CLCN3", "CLCN7", "CLIC4", "CLNS1A", "CLUH", "COLEC12", "COPS8", "COX5A", "COX7A2", "COX7A2L", "CPOX", "CPSF1", "CPT2", "CPVL", "CRTAP", "CSNK2B", "CSTF3", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DDB1", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "ECE1", "ERAP1", "ERMP1", "ETFDH", "ETNK1", "FNTB", "FOXRED1", "GALNT1", "GALNT4", "GM2A", "GMPS", "GOSR1", "GOSR2", "GSK3A", "KDELR1", "KDELR3", "L2HGDH", "LAMP1", "LAMP2", "LAPTM4A", "LBR", "LETM1", "LMAN2", "LNPEP", "LPCAT1", "MFSD3", "MIA2", "MIA3", "MICU2", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "NDUFB9", "NDUFS2", "NNT", "NPEPPS", "NPTN", "NRDC", "NSD2", "NTMT1", "NUCB1", "NUCB2", "NUP160", "NUP37", "NUP93", "OCIAD1", "OXA1L", "P3H1", "P3H4", "PAK1", "PARN", "PEX5", "PGRMC1", "PGRMC2", "PHGDH", "PI4KA", "PLA2G15", "PLBD2", "PMPCA", "PPT1", "PPT2", "PRCP", "PRKAA2", "PRMT1", "PRMT5", "PTGES2", "PTGR1", "PXMP2", "QSOX2", "RABAC1", "RCN2", "REEP2", "REEP3", "REEP4", "REEP5", "RPS6KA1", "RPS6KC1", "RRM2", "RRM2B", "SART1", "SC5D", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SEC11A", "SFXN2", "SIRT2", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SORT1", "SPNS1", "SQLE", "SSR1", "STT3A", "STX10", "STX18", "STX6", "SURF4", "SYNGR2", "SYNJ2BP", "SYS1", "TAP1", "TECR", "TIMM10B", "TIMM22", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED7", "TMED9", "TMEM165", "TMEM38B", "TMEM97", "TMPO", "TOE1", "TOMM40", "TPBG", "TPP1", "TRMT61A", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXN2", "UNC119B", "UQCR10", "UQCRC2", "VKORC1L1", "VPS11", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c2c9a89814544d67cab453c74790749979179bf3 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..e413689cf1efc0e79d7d6ee9bbbc9372bfdb3646 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06eafe5508ce45c1a7bbc5bc3e60e59802214fb7c788d8de30b6d51c779b3dc7 +size 191526 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a0739b7a1518393d576dba30d8ec5942decce175 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6ce4b14865babf33148992039f8d6df623db6bf9 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74a8f4d33d5c39b3051f6bbf59ded078cfb86e4a3811a727e9fc2b56b492d287 +size 132470 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..eaf99659a9a47753bac19260ef8af591ee8464f9 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:655f5b0a0169b05cf43c76f23deb77e95d8b2b7c4a7a1a2f6aa27b0e9f604a39 +size 138429 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..79f70b30914443862ab14d62c1823606ba947ff8 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97b1602e58ad79df5053810342b0d517bcbb3a7571018ff9f70687afcda31ee5 +size 71785 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1ab12e684767758c4706b2e5f056d48703ef3c98 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tclin 20 90 2.011701812837644 0.0442513794109118 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.0072023611660549 0.0919373334690581 0.1678646690679945 0.0834194084062932 0.0022180570570911 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6cf46ff07e3a07c4428891377d3dc13bbc046cb9 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 804.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e142b465f9759d7c51766f2e1a2b9fd9160365cd --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..882164b3d52dae68b855989d4ea0024371726c85 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.3933825051637067 2.0117018128376434 0.0442513794109118 0.1655991851533718 0.1770055176436473 90 O43676,P03886,P28074,P62942,P06280,O75306,Q13509,P00813,P49721,P05023,Q86Y39,P00374,Q99720,P20618,Q9Y2I1,Q9Y6M9,P21964,P38435,P10253,O43924 20 +Tdark 0.403072254920987 0.2399662534143568 0.810356418184945 0.998706541208169 1.0 343 Q8N8L6,Q9NX00,Q5SNT2,Q5VW38,Q92575,Q9P0S2,Q9H857,Q9Y6J9,Q15629,Q9NUJ3,O60830,Q9NX62,Q9BVG4,Q8N4V1,Q8WUA2,Q7Z4Q2,Q8NBN3,Q9Y320,O75964,O43731,Q5HYI7,Q8N4H5,P14649,Q9NPR9,Q96ER9,Q86U38,Q96H78,Q9NRY5,P61009,Q86YN1,Q9HD45,Q9UFG5,Q96CP7,Q9HD20,Q8TCD1,Q7Z7F7,Q8IYS2,Q7Z2K6,Q969T7,Q9H1E5,Q3SXM5,Q8NC54,Q9NWZ8,P82933,Q96GQ5,Q9H1Z9,P84157,Q5HYI8,Q8WVI0,Q9NUQ9,P14406,Q9H4I3,Q99805,Q9Y2W6,Q8NBM8,Q7Z3D4,Q8IZ69,O94919,Q6UW02,Q96ES6,Q9NR77,Q9BU23,Q9H7E9,Q8IXU6,O75935,Q6UW68,Q9NPA0,Q96FX7,Q9NPL8,Q9Y3B3,L0R6Q1,Q15005,Q96CN7,Q0P6H9,Q9Y3E0,Q8NBN7,Q8NFH4,Q8WUJ1,Q96S38,Q9Y5M8,Q92564,Q9BRK0,Q9Y5J6,Q9NUD5,Q96J42,O75071,Q70UQ0,Q8WZA9,Q9NVS2,Q96SK2,Q6NUQ4,Q96NB2,Q8N2H4,Q9BRJ2,Q96IX5,O95070 96 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5aa022d31bd0744fd96a1cba788c97a689aa7d3d --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRAT1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSDC1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C14orf2", "C16orf58", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPP", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG4", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", 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3.0155128003151412e-05 6.919512692359094e-05 1.8433829013364647e-05 +Lipid biosynthesis 26 63 2.251811720983985 0.0243341726733534 15.9126213592233 54.70145631067961 0.536392080403718 0.3712014565741516 7.84820404428356 6.53895703030749 1.480689631873909 0.3519149032884112 9.446488204951994e-07 0.0222515491745928 0.0071255358822931 0.0007668374373221 2.4209860935985278e-11 +Lipid metabolism 50 143 2.15615084371813 0.0310718884633771 32.65533980582524 126.3009708737864 0.0122638234126047 0.3570579745388888 13.120525890444084 12.789813112229345 1.8284441878622113 0.3670562446523409 9.990418440481326e-12 0.0163545954689415 0.0029868861111049 4.648188135637844e-09 3.854515125671403e-15 +Electron transport 21 52 2.079994796080809 0.0375260101871286 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 7.169442743417706e-06 0.0012680289055886 0.0150641135542582 2.0570050448998072e-05 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47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0017944194892132 0.0004573916663925 8.273714656149705e-05 0.0003907769995998 3.6909832453883604e-07 +Lipid transport 5 21 1.9671824649667624 0.049162178822917 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0140210550745271 1.0 0.0257983671639557 0.0046688430045599 0.0946135485635064 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..152da9e6990391d327c61d65b8176d781b104875 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 171, + "title": "Average number of proteins per term", + "value": 30.39766081871345 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fb5fe333d46dd6d17a3fdbd432484218db30e9e0 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1b9b5e25dc3c48503cdebb378f09387dc071ec3f --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Phospholipid metabolism 0.7542982665359232 3.3261779834944103 0.0008804568819926 0.1398293212132208 0.1412892029064483 20 Q96N66,Q9BVG9,Q8WUK0,P35790,Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q9NPH0,Q6P1A2,O14735,Q9UG56 12 +Phospholipid biosynthesis 0.743319511168255 3.146476519130455 0.0016525052971514 0.2463386460129118 0.1412892029064483 19 Q96N66,Q9BVG9,Q8WUK0,P35790,Q9HBU6,Q8NF37,O95674,Q9NUQ2,Q6P1A2,O14735,Q9UG56 11 +Steroid biosynthesis 0.6647201833616274 2.770319996216855 0.0056001244423946 0.6172268380967068 0.2011860409715876 23 Q15125,P48449,Q16850,Q53GQ0,Q9H3P7,Q15800,O75845,P54646,Q14739,Q15392 10 +Ion transport 0.5812780253990202 2.754252702682573 0.005882632776947 0.6353803847516897 0.2011860409715876 58 Q9H0H5,P98194,P21281,Q96AQ8,Q4KMQ2,P00846,P21796,P51798,Q9H4I9,Q9Y277,P05023,O96008,Q93050,O75964,Q9C0H2,Q9Y6M7,P45880,Q8NE01,P20020,Q9Y487,Q9NVV0,Q15904,Q96ER9,P24539,Q9H2J7,Q9Y696,P16615,P56385,P0CG08,O75947,Q9BVC6,P51790 32 +Sphingolipid metabolism 0.808228541271952 2.66892772765068 0.0076093821905036 0.7291473394110738 0.215563090909985 10 P07602,P04062,Q16739,O15269,Q9NZ01,O95470,P17900,Q13510 8 +Sterol metabolism 0.6115099981237885 2.426970435482817 0.0152254965287623 0.927457570970038 0.215563090909985 28 Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,O75845,P54646,Q14739,Q15392 11 +Cholesterol metabolism 0.6089595891999476 2.401260347133518 0.0163387073895169 0.9402146826883018 0.215563090909985 26 Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,P54646,Q14739,Q15392 10 +Sterol biosynthesis 0.6498784546170285 2.3833269446180068 0.0171569491200798 0.9481446818531968 0.215563090909985 17 Q15125,Q16850,Q15392,O75845,P54646,Q14739,Q15800 7 +Steroid metabolism 0.5933065163958902 2.3022000738622186 0.0213238918193736 0.9749235153683284 0.215563090909985 29 Q15125,Q16850,O15118,Q9H2C2,P04062,P35610,Q15800,O75845,P54646,Q14739,Q15392 11 +Cholesterol biosynthesis 0.6621647207656236 2.300317325779818 0.0214302488039166 0.9753852411327688 0.215563090909985 15 Q14739,Q15392,Q15125,Q15800 4 +Lipid biosynthesis 0.5062260786982946 2.251811720983985 0.0243341726733534 0.9851923175833684 0.2157103580198275 63 Q15125,P48449,Q16850,Q9HBU6,Q8NF37,Q9P035,O95674,Q9H3P7,Q9NUQ2,Q6P1A2,Q96G23,Q15392,Q8WUK0,Q53GQ0,Q9NZ01,O14735,Q14739,Q15800,Q9C0D9,Q96N66,Q9BVG9,O75845,Q9H7Z7,P54646,P35790,Q9UG56 26 +Lipid metabolism 0.445141309875241 2.15615084371813 0.0310718884633771 0.995472524332731 0.2332112279994918 143 Q86SQ9,Q15125,P48449,Q16850,O15118,Q9HBU6,Q8NF37,Q8NHP8,P04062,O95674,Q9P035,Q9H3P7,P35610,Q9NUQ2,O95470,Q9NPH0,Q6P1A2,Q8NCG7,Q96G23,Q15392,Q8WUK0,Q53GQ0,P23786,Q8NCC3,Q9UKU0,Q9NP80,O15269,P49748,P51648,Q9NZ01,Q14739,O14735,Q13510,Q15800,Q9C0D9,Q96N66,Q9BVG9,P07602,P09960,Q15067,O15254,O75845,Q9H7Z7,A1L0T0,Q9H2C2,Q14914,P54646,P35790,Q9UG56,Q8N2A8 50 +Electron transport 0.525149441061891 2.079994796080809 0.0375260101871286 0.9985561591876476 0.2406717116987753 52 O43676,P03886,O43169,O14949,Q96CU9,O75306,O95139,Q6DKK2,Q86Y39,Q99757,Q99643,O95864,Q9UDW1,Q9Y241,Q9NX14,Q9Y6M9,O75251,Q9H3N1,P22695,Q9H1E5,Q16134 21 +Sensory transduction 0.8269151650124511 2.0704196053874075 0.0384130674562961 0.9987667743750066 0.2406717116987753 5 Q9H6K4,P50897 2 +Vision 0.8269151650124511 2.0704196053874075 0.0384130674562961 0.9987667743750066 0.2406717116987753 5 Q9H6K4,P50897 2 +Amino-acid transport 0.7052829189820978 2.0176412997404465 0.0436286323513852 0.9995134329442188 0.2406717116987753 9 Q96NB2,P30825,Q96H78,Q9H2J7,Q6P4A7 5 +Translocation 0.5170777330480517 1.9853939579264197 0.0471006576796626 0.999738758810979 0.2406717116987753 51 Q9Y5J9,O14925,O75381,Q9BW27,Q9NS69,Q9BTX1,Q8NFH5,Q9Y584,P41208,Q8NFH4,Q99595,Q15629,P62072,O60830 14 +Lipid transport 0.5474355724257817 1.9671824649667624 0.049162178822917 0.999819614077682 0.2406717116987753 21 Q9H2V7,O15118,Q9BQE5,Q9BUR5,Q99720 5 +Respiratory chain 0.5291444386244609 1.8636107266750703 0.0623763901975864 0.9999835229519516 0.2596351521869991 36 O75306,O43676,P03886,Q86Y39,Q9UDW1,Q9Y241,P22695,O14949,Q9Y6M9,Q96CU9 10 +Calcium transport 0.6514679067253086 1.8567420467642997 0.063347862348984 0.99998619951996 0.2596351521869991 10 Q9H4I9,P98194,Q96AQ8,P16615,P20020 5 +Peroxisome biogenesis 0.7752273679721013 1.8475637386289523 0.0646654794755314 0.9999891519742145 0.2596351521869991 5 P56589,Q9Y5Y5,O75192 3 +Hydrogen ion transport 0.5198406365033973 1.7729692336766387 0.07623380509444 0.9999987084442457 0.2882977184126136 20 P21281,P24539,O75964,Q93050,P00846,Q9Y487 6 +Antiport 0.7008659363178864 1.7650594652476108 0.0775537722045627 0.9999989886042452 0.2882977184126136 7 P51798,P12236,P12235,P05141,P51790 5 +Unfolded protein response 0.6521852884073772 1.7426844839563431 0.081388743418862 0.9999995039431404 0.2961164920133066 9 Q9BUN8,Q15629,P55061,Q92575 4 +ATP synthesis 0.6600820003390155 1.6778612476410633 0.0933741892624169 0.9999999474949012 0.3258568645688427 8 P00846 1 +Sodium transport 0.6419787128350232 1.4782417729414938 0.1393430765736361 0.9999999999928232 0.4285476067066427 7 P05023,Q9Y6M7 2 +Potassium transport 0.6509023024268907 1.424341575052699 0.1543476179851133 0.9999999999996454 0.4630428539553399 6 Q9NVV0,Q96ER9,P05026,P05023,P55011 5 +Lipid degradation 0.4875520313123336 1.3182097092656624 0.1874334561767521 0.9999999999999996 0.5432393390885527 17 Q8NHP8,Q8NCC3,Q9NP80,Q8N2A8 4 +Symport 0.5710698423601631 1.2190852715760492 0.2228118294350334 1.0 0.6137812289185739 8 Q00325,Q9H2J7,Q9Y6M7,P53985,P55011 5 +Prostaglandin metabolism 0.8133932035602118 1.210388307429092 0.2261299264436851 1.0 0.6137812289185739 3 Q14914 1 +Ubiquinone biosynthesis 0.6091709777878338 1.1052046153077697 0.2690709374684701 1.0 0.646600936431283 5 Q8NI60,O75208 2 +Amino-acid biosynthesis 0.4997957541763009 1.1039863699316774 0.2695990502942107 1.0 0.646600936431283 11 O43175 1 +ER-Golgi transport 0.4132153783004426 1.0505354582013795 0.2934719974017308 1.0 0.6691161540759463 52 Q9Y282,Q15363,O95249,O43731,Q9P2W9,O95197,P24390 7 +GPI-anchor biosynthesis 0.5513533285759389 0.9498385636608132 0.3421942876351045 1.0 0.7490171964903566 6 Q9Y2B2,O43292,Q9H490 3 +Apoptosis 0.3373355086265564 0.9247163689572104 0.3551134625315997 1.0 0.7490171964903566 119 Q01085,Q9NR28,P55061,P05067,Q53EL6,Q9P0J0,Q96J02,O95470,P31751,O95197,O96017,P21796,O60566,O75340,Q9UDX5,O60313,Q07820,Q9Y371,P23396,Q96KA5,O95831,P09601,P51572,Q13546,O14737,Q9Y2I1,Q9UHX1,P61289,Q6NUQ4,Q03164,P12236,Q9H3K2,Q9NZJ7,Q96A26,P46379,Q15041,Q9BXK5 37 +Sugar transport 0.8458669981354829 0.8442088622932102 0.3985527031402909 1.0 0.7744603663294289 2 P31751 1 +Spermatogenesis 0.3876398511623364 0.7371204265585012 0.4610491182900609 1.0 0.8175162452011131 26 P46379,Q9H0H5,Q9Y2W6,Q8N2A8 4 +Sodium/potassium transport 0.6502953061858675 0.6236251043562886 0.5328738198056637 1.0 0.826768273515964 3 P05026,P05023 2 +Hypusine biosynthesis 0.7709757613424235 0.5950544808080445 0.5518070542492515 1.0 0.8424911274698393 2 Q9BU89 1 +Cilium biogenesis/degradation 0.356993219016392 0.5463306502432697 0.5848386711236484 1.0 0.8562130403112607 21 Q96J42,O95684,Q15154,A6NIH7 4 +Leukotriene biosynthesis 0.7221876942199877 0.449839646155225 0.6528260685162575 1.0 0.88749846303758 2 P09960 1 +Neurotransmitter transport 0.7181479179614549 0.438596646449708 0.6609538274009523 1.0 0.8899457046107311 2 Q9H2J7 1 +Fatty acid metabolism 0.3371803564798932 0.32653621604163 0.7440186931127548 1.0 0.928405648526716 51 Q9P035,P50416,O00767,P23786,O14975,Q8NCC3,Q9UKU0,Q6Y1H2,P49748,Q9NZ01,P51648,Q15067,O95864,O15254,Q9H7Z7,A1L0T0,Q14914,O14734,P54646 19 +Phagocytosis 0.5147653092943828 0.2401272712341846 0.8102315932215287 1.0 0.9489698797320644 3 Q96JJ3,P20339 2 +Nucleotide metabolism 0.3421831879922655 0.2031506340161224 0.8390172965432674 1.0 0.9664943398133544 11 Q969T7 1 +Chemotaxis 0.4132462686567115 0.1991440826582569 0.8421500387847358 1.0 0.9664943398133544 4 P09429,P26583,Q8NHP6 3 +Transport 0.4233491539114076 0.1506920199654571 0.880218668493139 1.0 0.9902460020547814 513 O43676,Q9H0H5,P03886,Q70HW3,Q9HC21,O43169,O14949,O95197,Q15629,P00846,O60830,P24390,P21796,A6NIH7,Q8N4V1,Q9Y282,Q15012,O95139,O00400,Q9Y6C9,Q9NS69,Q9Y584,O75964,Q9C0H2,O43731,Q9BQE5,O75431,Q5HYI7,P45880,Q8N4H5,Q99720,Q96ER9,Q9H2V7,P30825,Q96H78,Q92945,P51572,O95864,P49755,Q9UBU9,O75027,Q99595,Q9P2W9,O00461,Q9NX14,Q9HD20,Q9HCU5,Q6P4A7,Q8N1F7,Q53FT3,O14925,O75251,Q9UBX3,Q9BUN8,Q9H2D1,Q6NUK1,P46379,P61026,P33897,Q969X5,Q9H1E5,P21912,Q5BJH7,O75947,Q9BVC6,Q12769,O15118,Q4KMQ2,Q8TB61,Q15363,Q9Y619,Q13505,P50542,P50416,Q9UGP8,P62072,Q07955,Q96CU9,P20645,P05141,O60499,O95167,P51798,Q8NHS3,Q9H4I9,Q5JRA6,Q12893,P23786,Q8N5M9,Q86Y39,Q9BTX1,O95249,P09455,Q96RQ1,Q9BQT8,Q9UDW1,Q9Y241,P16260,Q9BUR5,Q96JB2,Q9H3N1,Q9H2C2,P12235,P08183,Q96ES6,P22695,Q16134,Q9NZZ3,Q8IXU6,Q03518,P31751,O75306,O43752,Q9Y277,Q93050,Q9Y6M7,Q9H4A6,Q969Q5,Q8NE01,Q99643,Q9Y487,Q9Y3B3,Q8NFH5,P41208,Q9Y696,P16615,Q9Y5J9,Q9Y6M9,Q9BSK2,Q9NZJ7,Q9Y3E0,Q9BW27,Q99523,Q8NFH4,O75381,P98194,P21281,Q96AQ8,O14653,Q9Y5J6,Q15907,O43264,O14964,Q96L92,P22626,Q6DKK2,P05023,O96008,Q99757,P63096,P24539,Q9H2J7,O43823,O43772,P53985,P56385,O60831,P12236,Q96NB2,Q9NR31,Q99442,Q8N2H4,P11166,Q99816,O95070,P51790 166 +Stress response 0.2906630905660106 0.0290572967364609 0.9768188936715752 1.0 1.0 28 P98179,Q14011,P51812,Q9Y241,O95197,Q9UHD1,Q15418,O95433 8 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9027b832198ee612d69fb8a803e1cdbf984273a7 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "Digestion", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEX1", "API5", "APOBEC3C", "APOL2", "APOO", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP2", "ARG2", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARMC10", "ARMT1", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AUP1", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BIRC6", "BMS1", "BNIP1", "BOP1", "BRAT1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD5", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CBL", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP55", "CERS1", "CERS2", "CETN2", "CFL1", "CGGBP1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST12", "CHST14", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "COASY", "COG3", "COG7", "COG8", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ5", "COQ8A", "COQ9", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDHD2", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIDO1", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSG2", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC10", "EMC4", "EMG1", "EML4", "ENO1", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAM162A", "FAM208A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXRED1", "FRG1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID8", "GINS1", "GINS2", "GINS3", "GINS4", "GLE1", "GLRX", "GM2A", "GMPS", "GNAI1", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPDH2", "INA", "INTS13", "INTS3", "INTS7", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JUP", "KARS", "KCMF1", "KCTD5", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN2", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPPRC", "LRRFIP1", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL14", "METTL3", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MOB4", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP5", "MRE11", "MRGBP", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK9", "NELFCD", "NELFE", "NES", "NFS1", "NGDN", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NLRX1", "NMD3", "NME1", "NME2", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NSA2", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC3", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PANK4", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHKA1", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POP1", "POP4", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPM1F", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", 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92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 1.6284071713744213e-07 0.0001544192587206 0.0012447112574106 5.383357697167809e-07 2.9804095218049224e-08 +Diabetes mellitus 5 13 2.0858278874557312 0.0369942163216516 3.1966019417475726 10.315533980582524 0.6190680538080506 0.4730085508812801 1.8480344075927575 1.973723369210009 0.8597438282474712 0.3113207504672028 0.1151696921634261 0.1747599807978781 0.3196260593385788 0.2421879711614701 0.1190174178925116 +Ichthyosis 2 11 1.9729598436303304 0.0485001376039888 2.424757281553398 8.70873786407767 0.6701903086786922 0.3798909770564678 1.5631275250389387 1.4270688811262522 1.102920967881483 0.3152318826682235 0.0435317720090838 0.1201219647894398 0.2263045436956677 0.0239571113561098 0.0351238878380088 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eeac14d0d1642f861853e6d8a5679d36583555c7 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 112, + "title": "Average number of proteins per term", + "value": 22.473214285714285 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8575cbbf3288ddfdefe24cae1c7cdafaf73bd529 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..760fbcfd2c723cd1d90d7972df6c5f83d55bc89e --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,39 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.4762007711787028 2.968945226507692 0.0029882385648438 0.2847933618210184 0.3346827192625136 99 O43676,Q99797,P03886,Q9Y2R0,Q70HW3,O14949,Q9BUB7,P00846,Q96CU9,O75306,O75208,Q6DKK2,Q86Y39,Q9Y584,Q9NPL8,O95831,Q9BQT8,Q7KZN9,P13073,Q9Y6M9,Q8NI60,Q9UBX3,P12235,Q5XKP0,P22695,Q7LG56 26 +Diabetes mellitus 0.6485436983038203 2.0858278874557312 0.0369942163216516 0.9853297913821945 0.5036585609386103 13 P03886,Q5VV42,P31751,P13807,O76024 5 +Ichthyosis 0.6485874481086621 1.9729598436303304 0.0485001376039888 0.9961825114825864 0.5036585609386103 11 Q15125,P04062 2 +Ehlers-Danlos syndrome 0.867245076086968 1.948430076006868 0.0513635239940759 0.99727617121609 0.5036585609386103 4 Q8NCH0 1 +Neuronal ceroid lipofuscinosis 0.8626660191035214 1.930026389716763 0.0536035680235007 0.9979098061784244 0.5036585609386103 4 O75503,P50897 2 +Cataract 0.538831065087114 1.902163519879608 0.057149780372508 0.9986272762872892 0.5036585609386103 29 Q15125,P48449,O00400,Q9H6K4,P11166,P08670,O76024,Q15800,Q9UG56 9 +Gangliosidosis 0.7745088008101327 1.8444311219933107 0.0651203352072822 0.9994695555818892 0.5209626816582578 5 P07602,P17900,P06865 3 +Peroxisome biogenesis disorder 0.697704279768085 1.6443671541302447 0.1001003855256437 0.999992591413343 0.6154202492366561 6 P56589,Q9Y5Y5,O75381 3 +Zellweger syndrome 0.697704279768085 1.6443671541302447 0.1001003855256437 0.999992591413343 0.6154202492366561 6 P56589,Q9Y5Y5,O75381 3 +Amyloidosis 0.7112104132360528 1.5651177621248331 0.1175552995125399 0.9999991739621996 0.6229078233651587 5 P03886 1 +Spinocerebellar ataxia 0.6208733850022037 1.4775487812925443 0.1395285922513636 0.9999999509677618 0.6794435796588141 8 Q8IV08 1 +Leber hereditary optic neuropathy 0.9925419515226842 1.3784344233382726 0.1680692014157778 0.9999999988785842 0.7529500223426847 2 P03886 1 +Hirschsprung disease 0.9586699813548788 1.2524326814063005 0.2104122439045572 0.9999999999967728 0.7941823890362493 2 P42892 1 +Gaucher disease 0.9568054692355468 1.2455209942382546 0.2129403032782044 0.9999999999977464 0.7941823890362493 2 P07602 1 +Leigh syndrome 0.5181664534585584 1.1102957182092852 0.2668716175957528 0.9999999999999992 0.8791065050213035 10 P00846,Q7KZN9 2 +Leukodystrophy 0.4295034789757719 1.033629938283088 0.3013091978632101 1.0 0.902369112868345 19 P07602 1 +Proto-oncogene 0.4154713409235667 0.9444792267575182 0.3449248123478243 1.0 0.910251121398739 39 Q8WY22,Q03164,O96028,P35637,Q92804,P49915,Q01105,P31751,Q16204,Q01844,Q15154 11 +FDA approved drug targets 0.3383544135708326 0.9391563906008203 0.3476504554336419 1.0 0.910251121398739 119 P49356,Q9NRF9,P98194,Q16850,P21281,P03886,Q8N0U8,P35610,P28074,P62942,Q13509,Q13423,P00813,P49721,P23786,P05023,P31350,P00374,Q99720,Q14534,P20618,P16615,Q9Y2I1,P21964,P38435,P10253,P12235,P54646,Q7LG56,Q16134 30 +Neurodegeneration 0.3493020308770582 0.9028224003534892 0.3666201605210093 1.0 0.9132021356994894 138 Q9Y287,P05067,Q9NQT5,P35637,P03886,Q9BRK0,Q13217,P04062,P27544,Q96A57,O14653,Q9UHD9,P06865,P50897,Q8NHS3,Q5T440,O00400,Q9NW15,P05023,O15269,Q9Y320,Q99757,O95831,P07196,Q13510,Q16637,Q9C0D9,Q99720,Q96B26,Q10713,O75298,Q13057,Q8IXJ6,O75503,O14773,Q6Y7W6,Q8NI60,Q14108,P54802,P61026,Q15041,Q8IV08,Q9NSD9 43 +Rhizomelic chondrodysplasia punctata 0.7003419334783826 0.7958617737775606 0.4261123818048649 1.0 0.9240090899098656 3 P50542,O15228 2 +Mucopolysaccharidosis 0.5763677692663595 0.751706604567908 0.4522275177339501 1.0 0.9240090899098656 4 P54802,P16278 2 +Amyotrophic lateral sclerosis 0.4169505381759941 0.666272055048021 0.5052372240418808 1.0 0.9315886701622368 13 Q99720 1 +Deafness 0.3715981050827828 0.6428241730044889 0.5203381959979532 1.0 0.9399657734156572 51 Q9NR28,Q9Y287,Q9NWM8,P21281,O00400,Q15067,O95831,O76024,Q9UG56,Q16740 10 +Progressive external ophthalmoplegia 0.4730760467747049 0.5861189996605378 0.5577955492522388 1.0 0.9916365320039802 6 P12235 1 +Retinitis pigmentosa 0.3723996177266269 0.4869838590945906 0.6262697694470805 1.0 1.0 16 P00846 1 +Parkinson disease 0.4181462316464903 0.4370991179135871 0.6620394669880671 1.0 1.0 8 P04062 1 +Epilepsy 0.3084467426118207 0.4091216804653799 0.6824503664841286 1.0 1.0 72 Q86SQ9,Q14108,O15047,P03886,P05023,Q9H2C2,Q9Y4G8,O75503,P11166,O14653,P16615,O14773,Q13510,Q9H490 14 +Primary microcephaly 0.3899339150863832 0.3948274633383348 0.6929702253353065 1.0 1.0 10 Q86XL3 1 +Hereditary spastic paraplegia 0.3241209778684686 0.3224644072502773 0.7471008977257068 1.0 1.0 20 O75298,Q9BRK0,Q9C0D9,O00400 4 +Parkinsonism 0.3473430488339408 0.2286043858952871 0.8191764153829852 1.0 1.0 11 P04062 1 +Premature ovarian failure 0.6280298321939191 0.2263887368461133 0.8208990872484907 1.0 1.0 2 Q06787 1 +Congenital disorder of glycosylation 0.3119960068244805 0.2192851047096154 0.8264279642681518 1.0 1.0 22 Q9HC07,Q8N511,Q9BV10,P51571,Q9BT22 5 +Allergen 0.5966438781852054 0.1720062107449666 0.8634326463050894 1.0 1.0 2 O43290 1 +Osteogenesis imperfecta 0.3538101913719141 0.1591702948836809 0.8735347067164598 1.0 1.0 8 O75718,Q9NVV0,Q96AY3 3 +Hereditary nonpolyposis colorectal cancer 0.548166563082673 0.108754837191993 0.9133969459653232 1.0 1.0 2 P43246 1 +Li-Fraumeni syndrome 0.4232442510876463 0.0393234056956749 0.9686325459992486 1.0 1.0 2 O96017 1 +Elliptocytosis 0.4226227470478736 0.0392043039170198 0.9687275022466648 1.0 1.0 2 O60488 1 +Dystonia 0.3166794965963792 0.028836111907976 0.9769952997091232 1.0 1.0 6 P11166,P04350,P51572 3 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f80b39b04c6f5982b277180d922a3ac90e454153 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital generalized lipodystrophy", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Phenylketonuria", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCD1", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT2", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANO10", "ANXA1", "ANXA11", "ANXA2", "ANXA7", "AP1B1", "AP1S1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APPL1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARV1", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATXN10", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRB", "BMS1", "BRAT1", 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a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..53bc4b144b9039cddd3e25516c99d9cf0829f033 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Glycosidase 7 16 2.6008354328490824 0.0092997053634023 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 0.0002876983905718 1.0 1.0 0.2781824052676386 0.0009402069411773 +Carboxypeptidase 3 6 2.546495305395592 0.0108810675112709 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0008878528391423 0.0711332726649859 0.0003823532959252 0.000366006536683 0.0048822579474643 +Receptor 14 37 2.540480363222378 0.0110700309830167 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0809910352492907 0.3479185756413622 0.0031164874966782 0.0399017324455896 0.2339314813187557 +Metalloprotease 8 27 2.284988731505256 0.0223134885098081 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 0.0018173194137189 0.2486824788491954 0.1106573079891401 0.0026306375243077 0.0017715044959542 +Translocase 8 22 2.1212523765180222 0.0339005697212255 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0096384400921869 0.2560754722464486 0.1170412325774002 0.0564393829037643 0.0022571444000092 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0070c99d7fac9d190c6aa4914310f6a97efb29d8 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 96, + "title": "Average number of proteins per term", + "value": 38.260416666666664 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..324ad17e8604deb69df8cd3aa600d126f9702c60 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0af9ac2354565248b874a011e9c1a2883f113775 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,27 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Glycosidase 0.6997384293494268 2.6008354328490824 0.0092997053634023 0.5921879570113894 0.2017627192767292 16 Q9BTY2,P04062,P04066,P54802,O60502,P06865,P06280 7 +Carboxypeptidase 0.9002667503588073 2.546495305395592 0.0108810675112709 0.6501697114950435 0.2017627192767292 6 P42785,Q9H3G5,P10619 3 +Receptor 0.6164225524530921 2.540480363222378 0.0110700309830167 0.6565277431979403 0.2017627192767292 37 O00264,Q14108,O15118,P30825,O15173,Q9NS69,Q99523,O43731,Q8WTV0,Q9Y2I1,Q14739,P24390,Q9Y5M8,Q99720 14 +Metalloprotease 0.5920199061691338 2.284988731505256 0.0223134885098081 0.8854054772189422 0.2116381691581843 27 O43847,P42892,P09960,O75844,Q7Z2K6,P55786,Q9NZ08,Q9UIQ6 8 +Translocase 0.5694937699413763 2.1212523765180222 0.0339005697212255 0.9635166007326824 0.2486596749449948 22 O75306,Q13423,P98194,P03886,Q03518,P08183,P16615,Q9HD20 8 +Monooxygenase 0.8948629748471424 2.0587643091830907 0.0395168222603405 0.9791542639013524 0.2529076624661798 4 Q9BU89,Q16850 2 +Porin 0.86691542288557 1.9471061963359984 0.0515220043018735 0.9937681506056596 0.3091320258112415 4 Q9Y277,P21796,P45880 3 +Ion channel 0.616897299499105 1.7933259008655442 0.07292082822632 0.999303028347968 0.3500199754863363 11 Q9NVV0,Q96ER9,Q4KMQ2,Q9Y696,Q9C0H2,Q9BVC6,P0CG08 7 +Host cell receptor for virus entry 0.5707381192342011 1.6790392269248249 0.0931443990136338 0.9999161194232704 0.3814425489173008 14 P11279,Q14108,Q8WTV0,O15118 4 +Protease 0.3655615079861074 1.6436951399113189 0.1002391903732562 0.9999605361910004 0.3849184910333039 82 O43847,P42892,Q9UIQ6,Q9H3G5,P09960,Q15005,O75844,P42785,Q9HB40,Q2T9J0,Q7Z2K6,P67812,P10619,P28074,P55786,Q9NZ08,O14773,Q16740 18 +Guanine-nucleotide releasing factor 0.5687194277068314 1.5602995144508087 0.1186891180890195 0.9999945999631104 0.3895959355038747 12 P80303,Q02818 2 +Prenyltransferase 0.69991181046345 1.5146332308032937 0.1298653118346249 0.999998414003231 0.3895959355038747 5 P49356,P49354,Q9Y5Z9 3 +Threonine protease 0.8451973888716194 1.3296112217276927 0.1836463988641123 0.9999999965300914 0.5185310085574938 3 P28074,P28072 2 +Acyltransferase 0.4533379227166683 1.247288454686082 0.2122917492123734 0.9999999998875192 0.5508110249834555 35 Q96N66,Q9BWD1,P23786,Q8NF37,Q8NCC3,P35610,Q9NUQ2,Q6P1A2,Q86UY6 9 +Chloride channel 0.6184125574144591 1.147025148340164 0.2513712274115409 0.9999999999991496 0.5870223758251375 5 Q9Y696,Q9C0H2 2 +Aminopeptidase 0.4973842719995492 1.1274528259605308 0.2595510749869554 0.9999999999997038 0.5870223758251375 12 Q9NZ08,P55786 2 +Voltage-gated channel 0.58556475850133 0.9986085106477244 0.3179843757502534 1.0 0.5918535929138796 5 Q9Y696,Q4KMQ2,Q9BVC6 3 +Oxidoreductase 0.3688995186307323 0.9889405445533784 0.3226922319682073 1.0 0.5918535929138796 158 Q16850,Q99536,Q8N0U8,P30519,Q9BU89,P30837,Q6NUM9,Q96CU9,Q15392,O75306,Q53GQ0,P31350,P49748,P51648,Q9NZ01,Q12797,O95831,Q9H9P8,Q14739,Q9BV57,Q8NBX0,Q15800,P00374,P09601,P13674,Q8NB78,Q14534,Q15067,O95864,O15254,Q8NBM8,P13073,O75845,P16435,Q9UBM7,O75251,Q9UHG3,Q02252,Q8N4Q0,Q14914,Q6UW02,Q8NBN7,O43175,P78417,Q7LG56,Q16134 46 +Glycosyltransferase 0.3936349264337345 0.7586414733178098 0.4480670562591466 1.0 0.6420431389044039 39 Q8N4A0,P04062,Q8NBI6,P46977,Q13126,O43505,Q10472,Q9BV10,P43490,Q9BT22 10 +Potassium channel 0.7806090739589842 0.6255537702098848 0.5316076694683045 1.0 0.6991004968350306 2 Q96ER9 1 +Rotamase 0.3563866508155972 0.5320304513464189 0.5947049050872724 1.0 0.7414502712776382 22 Q9NWM8,Q9Y680 2 +Dioxygenase 0.3817581132340488 0.4538881550296017 0.6499093294162201 1.0 0.7998884054353479 13 Q9BV57,Q12797 2 +Signal transduction inhibitor 0.6643878185208286 0.3024929557369801 0.762276302606208 1.0 0.8816689765083852 2 P49840 1 +Calcium channel 0.6559975139838496 0.2837196395615185 0.7766252427586327 1.0 0.8875717060098659 2 Q9UM00 1 +Methyltransferase 0.3224663865867278 0.1755727806750443 0.8606295880111161 1.0 0.938868641466672 44 Q03164,O60725,Q9BV86,O15047,O96028,Q96FX7,Q8IZ69,P21964 8 +Serine protease inhibitor 0.4305253341622689 0.0970298748380468 0.9227026696890546 1.0 0.9952747897769576 3 P05067,P35237 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e7b1e802848006772aaf6c8659cd9d4e8e32ff3b --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCD1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "ANKRD17", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT2", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BRD2", "BRD4", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC37", "CDC42", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP55", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "COQ5", "COQ8A", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDHD2", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DRG1", "DRG2", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "F11R", "FADS2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "KARS", "KCMF1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LEMD3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRPAP1", "LRPPRC", "LRRFIP1", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "M6PR", "MACF1", "MAGED2", "MAN2A1", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MATR3", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFN1", "MFN2", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTR", "MUT", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAT14", "NAXE", "NCBP2", "NCBP3", "NCEH1", "NCL", "NCOA5", "ND1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV1", "NDUFV2", "NEK9", "NELFCD", "NELFE", "NES", "NFS1", "NGDN", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NUS1", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD4", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDRG1", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PRSS3", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD9A", "RALA", "RALB", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBPMS", "RCC1", "RCC2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO4", "RFC1", "RFC3", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RING1", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNASET2", "RNF40", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENOI", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SUZ12", "SYNCRIP", "SYNE2", "TACO1", "TAF15", "TALDO1", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKT", "TLE3", "TMCO1", "TMEM109", "TMEM38B", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSFM", "TSN", "TSNAX", "TST", "TTK", "TTYH3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBIAD1", "UBLCP1", "UBR4", "UBR5", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC45A", "UPF1", "UPF3B", "UROD", "USP10", "USP11", "USP14", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "VANGL2", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WLS", "WNK1", "WRAP53", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YOD1", "YTHDC1", "YTHDC2", "YTHDF3", "ZADH2", "ZC3H13", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZFR", "ZMPSTE24", "ZNF148", "ZNF207", "ZNF281", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ABCB1", "ACADVL", "ACAT2", "ACOX1", "ACOX3", "ADI1", "AGPAT5", "AIFM1", "ALDH1B1", "ALDH3A2", "ALDH6A1", "ALG1", "ALG12", "ANO6", "APP", "ASPH", "ATP13A1", "ATP2A2", "ATP2C1", "B4GAT1", "CCDC51", "CLIC4", "CLPP", "COMT", "COX4I1", "CPT2", "CPVL", "CTSA", "CYP20A1", "CYP51A1", "DHCR24", "DHCR7", "DHFR", "DOHH", "ECE1", "ERAP1", "ERMP1", "ETFDH", "FADS2", "FKBP14", "FKBP7", "FNTA", "FNTB", "FOXRED1", "FUCA1", "FUCA2", "GALNT1", "GALNT4", "GBA", "GLA", "GPR89B", "GSK3A", "GSTO1", "HEXA", "HMOX1", "HMOX2", "HSD17B12", "ICMT", "KDELR1", "KDELR3", "KDM1B", "KMT2A", "L2HGDH", "LAMP1", "LBR", "LNPEP", "LPCAT1", "LPCAT3", "LTA4H", "MBOAT7", "MGEA5", 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sha256:04312d693b48e25d5abb97198808b86ab395c4e67251e41c838b0822f737c11e +size 140613 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..27a7f7097f3a0662806d82c2515a965e3293ee23 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:026ba9e189c2e0cf180a5bef3af1339f6db6b5800d0c7826c5bc774636d9334e +size 93608 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1a908ca57c2e76536edb14974ade2d8721c8815d --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 336 642 4.075637821425382 4.58883938549981e-05 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 1.3497510186069707e-49 3.675120870261161e-16 1.5769523361366429e-21 4.5570362647138466e-42 5.6541303407763515e-61 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c5918b758b9001e306377c3a03fb1d30f54e3020 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 513.25 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5a4329880a9f18d0bc8f7db8782de52dc2b21750 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f6a4fb6016b29b44e61fe7dc163da71a07efb4a1 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,8 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.6364033373732882 4.075637821425382 4.58883938549981e-05 0.0009173678957446 0.0004588839385499 642 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336 +Transporters 0.4831003853289554 1.2095783566343454 0.2264407272854085 0.994113299666738 0.5843377611641287 397 P56589,Q969V3,Q9H061,Q70HW3,Q5VW38,O60637,Q9P0S2,Q9HC21,Q8IYU8,P57088,Q15629,Q96AG4,P24390,Q8N4V1,Q8WY22,Q08722,O75844,O00400,Q8N511,O00560,Q9Y6C9,O14975,Q16739,Q9Y371,Q9Y320,Q9C0H2,Q8WTV0,Q12797,P45880,Q99720,Q9NQZ5,P35613,P07602,Q9H2V7,P30825,Q96H78,P51572,P49755,Q9UBU9,O75027,Q13438,Q9HD20,Q15070,Q9HCU5,Q6P4A7,Q9H300,Q8N1F7,Q14108,Q9UBX3,Q9BUN8,Q9H2D1,Q5BJF2,Q6NUK1,O15258,P33897,P21912,Q9BVC6,Q9Y287,P55061,P05067,Q12769,O15118,Q4KMQ2,Q8TB61,Q15363,Q9Y619,P49458,P13473,Q96A57,P50416,Q9BXS4,Q9UHB9,Q9UGP8,P20645,P05141,O75340,P51798,Q8NHS3,Q9H4I9,Q5JRA6,Q00325,O75192,Q9NW15,Q9BTX1,Q16891,Q9GZM5,O95433,P20020,Q96N66,O43808,P57105,Q9UBV2,Q9NVV0,Q9HC07,Q99805,Q9BQT8,P13073,P16260,Q96PC5,Q8TBA6,Q9BUR5,Q9Y5Y5,P54105,Q9H3N1,Q9H2C2,Q8NHH9,P12235,P08183,Q9NR77,Q8IXU6,Q03518,Q6UW68,Q9NPA0,Q96A33,O15260,P62942,Q8TAA9,O43752,Q8N8Q8,Q5T9L3,Q93050,Q9Y6M7,Q8NE01,O76024,Q99643,Q9Y3B3,Q96JJ7,Q9Y639,Q8NFH5,Q9Y696,P16615,Q9BSK2,Q9NZJ7,Q9BW27,O96005,Q99523,Q9UH99,Q8NFH4,P54646,O75381,Q07065,P98194,P21281,Q92544,Q9BUB7,P27105,Q96L92,Q9UI14,P05023,P11279,O96008,Q9H2J7,Q9UBU6,O43772,Q16799,P53985,O60831,P12236,Q96NB2,Q99442,P46977,P11166,Q9Y512,O75915 164 +FDA approved drug targets 0.3383544135708326 0.9391563906008203 0.3476504554336419 0.9998051917834584 0.5853354067996819 119 P49356,Q9NRF9,P98194,Q16850,P21281,P03886,Q8N0U8,P35610,P28074,P62942,Q13509,Q13423,P00813,P49721,P23786,P05023,P31350,P00374,Q99720,Q14534,P20618,P16615,Q9Y2I1,P21964,P38435,P10253,P12235,P54646,Q7LG56,Q16134 30 +Predicted secreted proteins 0.3991656047175133 0.9322618003156422 0.3512012440798091 0.9998253373002344 0.5853354067996819 53 Q9Y4P3,Q9Y287,Q92520,Q02818,Q9BTY2,Q08380,Q9HB40,Q8NBM8,P80303,P84157,Q8WUJ1,O94919,O60888,Q9NZ08,P43490,Q9BUR5 16 +CD markers 0.4421338432872315 0.7886309065481848 0.4303277615542193 0.9999870430997804 0.6620427100834144 12 P35613,Q08722,P11279,P13473,P08183,P08195 6 +Metabolic proteins 0.2938859614745016 0.5312426880261082 0.5952506150318215 0.9999999860772844 0.7440632687897769 904 O43676,Q15125,P03886,Q9HBU6,Q70HW3,P30519,P10619,O14949,P00846,Q15392,P50897,Q8N4A0,Q9BWD1,O75844,O00400,Q8NCH0,Q8NCC3,Q9UKU0,Q13126,O75964,Q8WTV0,Q9UMR5,Q14739,Q13510,Q8NBX0,Q15800,Q9NQZ5,Q9NWM8,P07602,P30825,Q86YN1,P49915,P55786,O60725,Q9UBX3,Q9UHG3,Q9H2D1,Q14914,P67812,O43175,Q969T7,P43490,Q8IV08,Q8N2A8,Q16850,O15118,Q9H773,Q8TB61,P04062,Q9Y619,Q9NUQ2,O95470,Q9NPH0,Q96G23,Q13423,Q53GQ0,O75192,P23786,Q9BRR6,Q9Y680,Q86Y39,Q9BTX1,Q9NP80,P51648,P09455,Q9BV10,Q9H9P8,Q9BV57,P00374,Q96N66,Q10713,Q9BQT8,Q9UDW1,O15254,P13073,O14773,P16260,O43292,Q03164,P52789,P12235,P08183,P54802,O43505,P22695,P78417,P35790,Q16134,O43924,Q15418,P49356,Q86SQ9,P48449,Q8NF37,O95674,O60502,P31751,Q10472,P11117,P53701,Q8NCG7,P62942,P06865,P06280,O75306,Q8WUK0,Q9BTY2,Q7LGA3,P04066,Q93050,Q9NZ01,Q9NRB3,Q9Y6M7,Q99643,Q9Y487,Q9BVG9,Q96JJ7,P09960,Q8IXJ6,Q15067,Q8NFH5,P10644,P16615,Q9Y6M9,P16435,P17858,P21964,Q15005,O96028,Q9H7Z7,Q9BW27,P10253,Q8N4Q0,Q8NBN7,Q8NFH4,Q96S38,P54646,Q7LG56,Q86UY6,Q9H490,Q9UG56,Q9NSD9,Q9NRF9,P98194,P21281,Q9P035,P35610,P30837,Q6P1A2,Q9BT22,P00813,Q9NX47,Q9Y5Z9,P05023,O15269,P31350,P49748,Q99757,Q15165,O14735,Q9C0D9,Q9Y2B2,Q96EY8,P25325,O15047,P24539,Q9H2J7,Q14534,P51812,O43772,O75845,P51571,P53985,Q9UBM7,P56385,P12236,Q6P2P2,Q02252,P46977,P11166 180 +Disease related genes 0.2421382679781863 0.332508252189198 0.7395055095069354 0.99999999999793 0.8700064817728652 1019 P56589,O43676,Q4J6C6,Q15125,P03886,Q9H061,Q9H6K4,Q70HW3,O75718,P27544,Q9HC21,P10619,P17900,O14949,Q16204,P00846,Q01844,P10586,O60566,Q15392,Q15154,P50897,O75844,O00400,Q8N511,Q8NCH0,Q9UKU0,Q13126,Q9Y584,O95831,Q14739,Q13510,Q15800,Q99720,Q9NWM8,P07602,O75503,O75027,P49915,Q9UHX1,Q16740,Q53FT3,Q14108,Q9H2D1,O43175,Q5XKP0,Q9ULK5,O95684,Q8IV08,Q9Y287,P42892,Q86XL3,Q96EK5,O15118,Q9Y2R0,P04062,Q9Y619,O95470,Q96CU9,Q13509,P51798,Q13423,P23786,Q8N5M9,Q86Y39,Q9NP80,P51648,Q9BV10,Q9H9P8,Q5HYI8,P00374,Q96N66,Q10713,Q9HC07,P28070,Q9BQT8,Q5VV42,P13073,O14773,Q96PC5,O43292,Q8TBA6,Q8NI60,Q9Y5Y5,Q03164,P38435,Q9H2C2,P12235,P08183,P54802,O43505,P22695,Q16134,O43924,Q86SQ9,P48449,P35637,Q03518,Q9Y4G8,Q96A33,P31751,P11117,P53701,Q8TAA9,P06865,P06280,O75306,O75208,Q92804,P04066,O75419,Q9NZ01,Q9NPL8,P55795,O76024,Q99643,Q9Y487,O00165,O14979,Q7RTS9,Q15067,Q7KZN9,P10644,P16615,Q9Y6M9,P16435,P21964,O96028,Q9BW27,P10253,Q99523,Q8NFH4,Q7LG56,O75381,Q9H490,Q9NSD9,Q9NR28,Q99797,P98194,P21281,Q9BRK0,O14653,Q01105,Q9NVI7,Q9BUB7,Q15907,Q9BT22,Q9Y4P3,P22626,P00813,Q9Y5Z9,Q6DKK2,P05023,O15269,P49748,Q96J42,Q99757,P07196,P08670,P98175,Q9C0D9,Q96B26,Q9Y2B2,Q96EY8,P25325,O75298,O15047,P51812,O43772,O75845,P51571,P53985,Q9UBM7,Q9H3L0,P50402,Q02252,P46977,P11166,Q96HY6,Q96IX5,Q9H4L7,Q15041,P10321 183 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7cd11740075c08c2bff5f4d694794842c953a476 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD12", "ABHD14B", "ABHD16A", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT2", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH16A1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOL2", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARV1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAX", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRAT1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSDC1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C14orf2", "C16orf58", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C3orf58", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC23", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPP", "CENPV", "CEP170", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ5", "COQ8A", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX16", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "CYP7B1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPF2", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "F11R", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FOXRED2", "FRG1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GXYLT1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HECTD3", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HINT3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "IRS4", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KCMF1", "KCTD12", "KCTD5", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LPCAT3", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYRM7", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL3", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMADHC", "MMGT1", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL55", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS18A", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR12", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS5", "NDUFS6", "NDUFS7", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NGDN", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUS1", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX11A", "PEX11G", "PEX13", "PEX14", "PEX16", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGL", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABAC1", "RABEP1", "RABGAP1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALB", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASET2", "RNF40", "RNH1", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDHC", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENOI", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLC30A7", "SLC30A9", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG5", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPOUT1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIM2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TK1", "TKT", "TLCD1", "TLE3", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM259", "TMEM33", "TMEM38B", "TMEM41A", "TMEM43", "TMEM59", "TMEM62", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOP3A", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOR3A", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXN2", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "ULK3", "UMPS", "UNC119B", "UNC45A", "UPF1", "UPF3B", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VANGL2", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VKORC1L1", "VMA21", "VPS11", "VPS13A", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC2A", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR6", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP53", "WRAP73", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "XXYLT1", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YOD1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF148", "ZNF207", "ZNF281", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD1", "ACADVL", "ACAT2", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADA", "ADI1", "ADPGK", "AGPAT5", "AGTRAP", "AHSA1", "AIFM1", "AKT2", "ALDH1B1", "ALDH3A2", "ALDH6A1", "ALG1", "ALG12", "ANKLE2", "ANO10", "ANO6", "APOL2", "APOO", "APP", "ARL10", "ARL6IP1", "ARL6IP5", "ARV1", "ASAH1", "ASPH", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5F1", "ATP5I", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "AUP1", "B4GAT1", "BCAP31", "BCL2L13", "BRI3BP", "BSG", "BUB1B", "C16orf58", "C18orf32", "C19orf70", "C5orf15", "CANX", "CCDC47", "CCDC51", "CCDC6", "CD47", "CDC45", "CDIPT", "CDKAL1", "CDS2", "CERS1", "CERS2", "CHKA", "CHST12", "CHST14", "CISD1", "CKAP4", "CLCN3", "CLCN7", "CLIC4", "CLN5", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CNNM3", "COA3", "COMT", "COQ8A", "COQ9", "COX11", "COX15", "COX16", "COX18", "COX4I1", "COX7A2L", "CPD", "CPT1A", "CPT2", "CRTAP", "CTSA", "CUTA", "CYB5B", "CYB5D2", "CYP20A1", "CYP51A1", "DAGLB", "DCTPP1", "DDRGK1", "DERL1", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DIABLO", "DNAJC1", "DNAJC11", "DOLPP1", "DYM", "EBP", "ECE1", "EFCAB14", "EIF3L", "EMC7", "EMD", "ENDOD1", "ERAP1", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "ETFDH", "ETNK1", "EWSR1", "EXOSC8", "EXTL3", "FADS2", "FAM162A", "FAM3C", "FAM8A1", "FARSB", "FGFR1OP", "FKBP14", "FKBP1A", "FKBP7", "FNTB", "FOXRED1", "FUCA1", "FUCA2", "FUS", "GAA", "GALNT1", "GALNT4", "GBA", "GGCX", "GHITM", "GLA", "GM2A", "GMPS", "GOLGA5", "GOLIM4", "GOLT1B", "GOSR1", "GOSR2", "GPAA1", "GPR107", "GPR108", "GSTO1", "GTF3C3", "HACD2", "HACD3", "HAX1", "HCCS", "HEXA", "HIGD1A", "HIKESHI", "HK2", "HLA-C", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HS2ST1", "HSD17B12", "HSDL1", "ICMT", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KIAA0319L", "KIAA2013", "KIFBP", "KMT2A", "L2HGDH", "LAMP1", "LAMP2", "LAPTM4A", "LBR", "LGALS3BP", "LMF2", "LNPEP", "LPCAT1", "LPCAT3", "LRRC59", "LSS", "LTA4H", "LYSMD3", "M6PR", "MARCH5", "MAVS", "MBOAT7", "MCUR1", "MFSD3", "MFSD8", "MGEA5", "MIA2", "MIA3", "MICU2", "MIPEP", "MMAB", "MMADHC", "MMGT1", "MPST", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MXRA7", "NAA40", "NAGLU", "NAMPT", "NCLN", "ND1", "NDC1", "NDUFA11", "NDUFA3", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB9", "NDUFS2", "NEFL", "NISCH", "NNT", "NPC1", "NPEPPS", "NPTN", "NRM", "NSD2", "NT5C3B", "NUCB1", "NUCB2", "NUP160", "NUP35", "NUP37", "NUP85", "NUP93", "NXF1", "OCIAD1", "OPA3", "OS9", "OXA1L", "PARL", "PCM1", "PCYOX1", "PCYOX1L", "PDCD6", "PDE6D", "PEX11A", "PEX11G", "PEX14", "PEX16", "PEX3", "PFKL", "PGRMC1", "PGRMC2", "PHGDH", "PI4KA", "PIGL", "PIGU", "PISD", "PLA2G15", "PLD3", "PLD6", "PMPCA", "PNPLA8", "POLE3", "PON2", "POR", "PPT1", "PPT2", "PRAF2", "PREB", "PREPL", "PRKAA2", "PRKAR1A", "PRMT9", "PSAP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PTDSS2", "PTGES2", "PTGR1", "PTPMT1", "PTPRF", "PUF60", "PXMP2", "RAB11B", "RABAC1", "RABL3", "RAPGEF2", "RBM10", "RBP1", "RDH13", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RETSAT", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RRM2", "RRM2B", "RTN1", "RTN2", "RTN3", "RTN4", "SACM1L", "SAMM50", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCPEP1", "SDCBP", "SDHB", "SDHC", "SEC11A", "SEC62", "SEC63", "SEL1L", "SELENOI", "SET", "SETD1A", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT2", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A7", "SLC6A15", "SLC7A1", "SMARCAD1", "SMDT1", "SMIM4", "SNX27", "SOAT1", "SORT1", "SPCS2", "SPNS1", "SPTLC1", "SQLE", "SRP68", "SRP9", "SRPRB", "SSR1", "SSR4", "STARD3NL", "STARD7", "STOM", "STT3A", "STX10", "STX18", "STX6", "SUN2", "SURF4", "SYNGR2", "SYNJ2BP", "SYS1", "TAF15", "TAP1", "TBL2", "TDRKH", "TECR", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMMDC1", "TLCD1", "TM9SF2", "TM9SF3", "TM9SF4", "TMBIM6", "TMED10", "TMED2", "TMED7", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM160", "TMEM165", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM59", "TMEM62", "TMEM70", "TMEM87A", "TMEM97", "TMX1", "TMX2", "TMX3", "TMX4", "TOMM22", "TOMM40", "TPBG", "TPP1", "TRABD", "TRAM1", "TRIM13", "TSPAN3", "TSPAN6", "TTC19", "TTYH3", "TUBB3", "TXN2", "TXNDC15", "UBIAD1", "UBXN4", "UGCG", "UQCR10", "UQCRC2", "UQCRQ", "USMG5", "VANGL1", "VANGL2", "VDAC2", "VIM", "VKORC1L1", "WFS1", "WLS", "YIF1A", "YIF1B", "YIPF3", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json 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0000000000000000000000000000000000000000..80d052a34b316ee51766e4b3c7b0cb1dfd56d7e8 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:029c3f8186fa83aca5c6f4fb20ff80821a3acae8d878441a94cae0294620a3db +size 80346 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0c6b9d4dd8edc94580563abaca9476d17163eb77 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3220, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 148.87878787878788 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e5362954f15daf7becf23f5b807eaf7926f5ec68 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C288/C288_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..60e85d235bfc7f7990744970aef9766a1244a6a6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.466022306326832 1.8746432791390488 0.0608418149441563 0.8739976399343921 0.4015559786314316 211 Q15125,Q86XL3,Q16850,Q03518,Q6UW68,Q8NF37,Q00765,O95674,P27544,Q8N0U8,Q92575,Q96A33,O15260,Q9BRK0,O43169,Q96A57,P43307,O95470,O95197,P35610,Q96G23,O43264,Q9BT22,Q92791,Q9Y680,Q5T9L3,O15269,P84157,P51648,O43731,Q96KA5,Q9BV10,Q9NQC3,Q9NZ01,Q5HYI8,Q15800,Q9H3G5,Q9P035,Q14257,Q70UQ0,Q9P2W9,O75845,P27824,Q16799,P51571,Q96PC5,O43292,Q9UBM7,P21964,Q6NUQ4,O60831,P50402,Q96CN7,Q9BUN8,Q9H3N1,Q9NR31,O96005,Q5BJF2,Q8NHH9,Q86UE4,O43852,Q99442,Q96HY6,Q8WUJ1,Q15041,P35790,Q96KC8,O75915,Q8IV08,O00264 70 +Golgi apparatus 0.4474580722971044 1.7561995778044337 0.0790543367783571 0.9339728981938892 0.4347988522809644 194 Q9Y287,Q02818,Q9H8Y8,Q8IXU6,P98194,Q6RW13,Q5VW38,Q9H3P7,O60637,P80303,O15260,O43760,O14653,Q9NUJ3,P10586,P24390,Q8NC54,O60499,P50897,Q8N4A0,O43752,Q15012,Q8NBN3,Q96GQ5,Q8NCH0,Q9NP80,Q93050,Q96J42,Q9NRB3,Q8IZA0,Q9GZM5,Q9H4A6,Q9BV57,O75071,Q92520,Q9NWM8,Q9NPR9,Q9H2V7,Q9HC07,Q7RTS9,Q96RQ1,Q9UBU6,O00231,Q9HD45,O00461,Q8TBA6,Q6NUQ4,Q96JB2,Q8IYS2,A1L0T0,Q9HB40,Q8N4Q0,Q99523,P67812,P54646,O95070,Q5BJH7,Q9UG56 58 +Lipid droplets 0.4724404748178342 0.9742646310561752 0.329925161261567 0.9999981716082752 0.7137029285397692 12 Q8NF37,Q969V3 2 +Lysosomes 0.4377885177689949 0.833016863474581 0.4048352186777992 0.9999999634381304 0.7137029285397692 14 Q96S38,Q8WTV0 2 +Microtubules 0.390544969873046 0.7970564414598378 0.425418252399558 0.999999988555146 0.7137029285397692 49 Q6NXT1,Q02818,P54105,Q14498,P55209,Q9Y2I1,O60830,Q9NZZ3,Q13509 9 +Centriolar satellite 0.3928065505605089 0.7714888515355843 0.4404172279456739 0.9999999952189524 0.7137029285397692 27 Q03518,Q86UY6,Q15907,P41208,O43169,Q14498 6 +Nuclear membrane 0.3397247458330032 0.7484735208503999 0.4541745908889441 0.9999999978973174 0.7137029285397692 71 Q9H1E5,P50402,Q8IXM6,Q6BDS2,Q6UW68,Q5SNT2,O14735,Q9BTX1,Q8NFH5,O15260,Q9UH99,P67812,O94919,Q14739,Q96G23,Q96SK2 16 +Peroxisomes 0.3616338072511831 0.4536975824775553 0.6500465071806043 0.9999999999999992 0.9043708076557666 17 O75381,Q15067,O15254 3 +Intermediate filaments 0.3388675954805979 0.3154102464334535 0.7524501880645802 1.0 0.9043708076557666 35 Q96K76,Q99442,O75718,Q86YN1,Q3SXM5,Q9UFG5,P07196,P08670 8 +Midbody 0.3416509658298652 0.2958496190239135 0.7673449277079232 1.0 0.9043708076557666 16 Q6NXT1,Q9NZZ3 2 +Focal adhesion sites 0.3166047558283948 0.2032258874901468 0.8389584797166179 1.0 0.9546768907120134 27 Q969Q5,P08183,O60888,Q9Y6M7 4 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..abe67f7b88b01af3cdb45f079c504c20b5ec407e --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABHD10", "ABHD14B", "ABHD6", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG2", "ALG5", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKRD54", "ANLN", "ANO10", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "APEH", "APEX1", "API5", "APMAP", "APOBEC3C", "APOO", "APOOL", "APP", "APPL1", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARID1A", "ARID2", "ARIH1", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARV1", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B4GALT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRAT1", "BRD2", "BRD4", "BRI3BP", "BRIX1", "BRK1", "BROX", "BSDC1", "BSG", "BTF3", "BTN2A1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C14orf2", "C16orf58", "C17orf75", "C18orf32", "C19orf25", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C5orf15", "C5orf51", "C8orf33", "CAB39", "CACUL1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNA2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CCZ1B", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPP", "CENPV", "CEP170", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGGBP1", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD4", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST12", "CHST14", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTC", "CLUH", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNOT1", "CNOT10", "CNOT2", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ5", "COQ8A", "COQ9", "CORO1B", "COTL1", "COX15", "COX16", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDHD2", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHDDS", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP4", "DLGAP5", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH2", "DPH5", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL2", "EARS2", "EBNA1BP2", "EBP", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FABP5", "FAF1", "FAF2", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM208A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS2", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HEXA", "HGH1", "HGS", "HIBCH", "HIGD1A", "HIKESHI", "HINT2", "HINT3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPAD1", "IMPDH2", "INA", "INF2", "INTS13", "INTS14", "INTS3", "INTS4", "INTS7", "INTS9", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRGQ", "ISCU", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JPT2", "JUP", "KARS", "KCMF1", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLPH", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LPCAT2", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC47", "LRRC59", "LRRFIP1", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM4", "LSM6", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYN", "LYPLA1", "LYPLA2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD2L1", "MAGED2", "MAIP1", "MAK16", "MAN2A1", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBNL1", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED1", "MED14", "MED17", "MED21", "MED23", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL13", "METTL14", "METTL7B", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MGMT", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL58", "MRPL9", "MRPS10", "MRPS15", "MRPS16", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MVK", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYO19", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAT14", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAB1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NELFCD", "NELFE", "NEMF", "NES", "NFATC2IP", "NFS1", "NGDN", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NLRX1", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE2", "NSRP1", "NSUN2", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NUS1", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCIAD2", "OCRL", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD4", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX13", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGL", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLRG1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA2", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2D", "POLR2E", "POLR2F", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POM121C", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD9A", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM45", "RBM6", "RBM8A", "RBMX", "RBMXL1", "RBP1", "RBPMS", "RCC1", "RCL1", "RCN1", "RCN2", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RHOT2", "RIC8A", "RIF1", "RING1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF40", "RNH1", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS27", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS6KC1", "RPS7", "RPS8", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAAL1", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCLY", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIN3A", "SIN3B", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A16", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG5", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPCS2", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TACO1", "TAF10", "TAF15", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "THEM6", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TIPRL", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM11", "TMEM115", "TMEM126A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM223", "TMEM230", "TMEM245", "TMEM259", "TMEM41A", "TMEM62", "TMEM70", "TMEM87A", "TMEM97", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM25", "TRIM26", "TRIM28", "TRIP12", "TRIP13", "TRIR", "TRMT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRUB1", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSR1", "TST", "TTC1", "TTC19", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXLNG", "TXN2", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBIAD1", "UBLCP1", "UBQLN2", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UHRF1BP1", "UMPS", "UNC45A", "UPF1", "UPF3B", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "URGCP", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VKORC1L1", "VPS11", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC2A", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR41", "WDR46", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIZ", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YAP1", "YARS", "YARS2", "YBX1", "YEATS4", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YOD1", "YRDC", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H13", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYND8", "ZNF148", "ZNF207", "ZNF281", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZSWIM8", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ACBD3", "ACOX1", "ACOX3", "ADI1", "AGTRAP", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "ANKRD54", "ARL6IP1", "ARL6IP5", "ATL2", "ATP2C1", "ATP6V0A1", "C16orf58", "C19orf25", "C5orf15", "CALU", "CANX", "CCDC47", "CDIPT", "CDS2", "CERS1", "CERS2", "CETN2", "CHKA", "CHMP5", "CHST12", "CHST14", "CLNS1A", "CLPTM1", "CLPTM1L", "COG3", "COMT", "CPVL", "CRTAP", "CUTA", "CYB5B", "CYB5D2", "CYP51A1", "DDRGK1", "DERL1", "DHCR7", "DNAJC1", "DOLPP1", "DYM", "EBP", "EFCAB14", "EMD", "ENDOD1", "ERGIC2", "FAM3C", "FAM8A1", "FKBP14", "FKBP7", "GALNT4", "GOLGA5", "GOLIM4", "GOLPH3", "GORASP2", "GOSR2", "GPAA1", "GPR107", "GPR108", "HACD3", "HSDL1", "IKBIP", "ILVBL", "ISOC1", "ITM2B", "KDELR1", "KDELR3", "KIAA0319L", "KIAA2013", "LAPTM4A", "LBR", "LPCAT1", "MIA2", "MSMO1", "MTDH", "MXRA7", "NAA40", "NAP1L1", "NCLN", "NDC1", "NEFL", "NISCH", "NRM", "NUCB1", "NUCB2", "NUP35", "P3H4", "PEX14", "PGRMC1", "PISD", "PLD3", "PNPLA8", "PPT1", "PRAF2", "PRKAA2", "PSMD11", "PTPRF", "RAB11B", "RAB24", "RABL3", "RBM39", "RCN2", "REEP2", "REEP5", "RPS6KC1", "RTN1", "RTN3", "RTN4", "SAR1A", "SC5D", "SCARB1", "SCPEP1", "SEC11A", "SEC62", "SGPL1", "SLC35F2", "SLC4A7", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "SSR1", "SSR4", "STX10", "STX18", "STX6", "SUN2", "SURF4", "SYNGR2", "TAP1", "TCP11L1", "TECR", "TIMM17B", "TM9SF3", "TMEM165", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM87A", "TMEM97", "TMX1", "TMX4", "TSPAN3", "TUBB3", "TXNDC15", "UBXN4", "UHRF1BP1", "USP47", "VIM", "VKORC1L1", "WLS", "YIF1A", "YIF1B", "YIPF3", "ZADH2", "ZW10"]} \ 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