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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:43269e1aeb939da9fb14e0783862a584b8ddae52e6a803031342a24777107d5a
+size 79058

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.508771929824561
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C289/C289_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7162834058421441	0.8778493166386842	0.3800254971454904	0.9999999999985368	0.5508742407585653	2	Q7LG56	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.2741421541535355	0.249587384898099	0.8029064552921763	1.0	0.847512369475075	45	Q15418,P06493,Q13177,Q99640,P49841,Q13546,P54646,Q13153,P49840	9
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.3404850746268575	0.0027465268308299	0.9978085914009658	1.0	0.9986218090389444	4	P38606,P06576,P21281	3

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PRSS3", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ATP5B", "ATP6V1A", "ATP6V1B2", "CDK1", "GSK3A", "GSK3B", "PAK1", "PAK2", "PKMYT1", "PRKAA2", "RIPK1", "RPS6KA1", "RRM2B"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]", "2": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:62decb7c3ebd5804c5ecb3e76106ba8779f7043120733f994530e2d788d70e16
+size 75924

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.5
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C289/C289_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,7 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.5023342670401713	0.8043529834021247	0.4211931463440346	0.9999999748187504	0.5183915647311195	7	Q9BVA1,P07437,P68371,Q13509,Q9BUF5,P04350	6
+EF-Hand 1, calcium-binding site [IPR018247]	0.3248144918290324	0.721891485710006	0.4703611963840206	0.9999999985298776	0.5574651216403207	39	Q9Y680,Q6NUK1,O75340,P41208,Q15293,Q9UBV8,P80303,O43852,Q9NWM8,O75746,Q14257,Q9BPX6,P43304,O95202,Q02818	15
+Peptidase M16, zinc-binding site [IPR001431]	0.5158478896689943	0.6283791624873232	0.5297555841844697	0.9999999999673144	0.6054349533536796	5	Q10713	1
+Protein kinase, ATP binding site [IPR017441]	0.2905968227688679	0.4274901737757769	0.6690223406711076	0.9999999999999996	0.7382315483267393	43	Q15418,P06493,Q13177,Q99640,P31751,P49841,Q9P289,Q16539,P54646,Q13153,P49840,P24941	12
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.494406463642029	0.1750433642264511	0.8610455598385562	1.0	0.9184485971611268	2	O15270	1
+Aconitase family, 4Fe-4S cluster binding site [IPR018136]	0.3974518334369288	0.0567486034719497	0.954745456397392	1.0	0.9665846564162436	2	P21399	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK13", "CDK2", "CDK4", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LPCAT2", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K5", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH9", "MYO19", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1"], "leading_proteins": ["ACO1", "AKT2", "CALU", "CDK1", "CDK2", "CETN2", "FKBP14", "FKBP7", "GPD2", "GSK3A", "GSK3B", "LETM1", "MAPK14", "MICU1", "NUCB1", "NUCB2", "PAK1", "PAK2", "PDCD6", "PEF1", "PKMYT1", "PMPCA", "PRKAA2", "RCN1", "RCN2", "RPS6KA1", "SLC25A12", "SLC25A24", "SPTLC2", "STK26", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:2ff54f5d71a713d2bb6bfebb4ca2d65b7ba3bd99d79856ad80753d5830816590
+size 96498

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Syntaxin/epimorphin, conserved site [IPR006012]	2	8	2.134888911477089	0.0327700852916712	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.01807161676056	0.0595353304203936	0.0063961411835862	0.003279014583115	0.022238421566873

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 273,
+    "title": "Average number of proteins per term",
+    "value": 2.58974358974359
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C289/C289_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7367624092948591	2.1348889114770895	0.0327700852916712	0.999887897947215	0.1754163389142402	8	Q9P2W9,O60499	2
+Thioredoxin, conserved site [IPR017937]	0.6111124761662637	1.9437080518539465	0.0519306671030364	0.999999524284884	0.2025296017018419	12	Q9H1E5,Q96JJ7,Q9H3N1,Q99757	4
+Intermediate filament protein, conserved site [IPR018039]	0.6683826506234056	1.7894264376269786	0.0735461647536634	0.9999999991232156	0.247877814540125	8	P08670,Q16352,P07196,P02545,P07197,Q03252	6
+Haem oxygenase conserved site [IPR018207]	0.9083281541329962	1.6832604582404738	0.0923246815272575	0.9999999999967264	0.2673448660219185	2	P30519	1
+Tetraspanin, conserved site [IPR018503]	0.89586571339757	1.455031981137488	0.1456604079426353	1.0	0.366883701551674	3	O43657,O60637	2
+Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]	0.8306401491609545	1.3537361552002078	0.1758205689089096	1.0	0.3826124762580894	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]	0.8306401491609545	1.3537361552002078	0.1758205689089096	1.0	0.3826124762580894	2	Q07820	1
+Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]	0.8306401491609545	1.3537361552002078	0.1758205689089096	1.0	0.3826124762580894	2	Q07820	1
+UbiE/COQ5 methyltransferase, conserved site [IPR023576]	0.814481044126789	1.2853108420688182	0.1986836829463492	1.0	0.4078244018372431	2	Q5HYK3	1
+AMP-binding, conserved site [IPR020845]	0.5840036081616299	1.2251903263882635	0.2205035184082744	1.0	0.4368739378181101	7	O14975,Q9UKU0	2
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.8195115696898052	1.1578981063450922	0.2469056204073281	1.0	0.4568120522120919	3	Q5T8D3	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.7784338098197676	1.133554955954854	0.2569812766065571	1.0	0.4708448893529537	2	P11279	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5802638132724746	1.120150310561868	0.2626497143906618	1.0	0.4742530944639437	6	Q14566,P33993,P33991	3
+Sterol reductase, conserved site [IPR018083]	0.7333747669359905	0.9470909821922102	0.343592419497853	1.0	0.5300828295018799	2	Q14739	1
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.7615791109729568	0.9355495457891408	0.3495051623089318	1.0	0.5300828295018799	3	Q8WWV3,Q99536	2
+Tubulin, conserved site [IPR017975]	0.5024906600249048	0.9065298716532332	0.3646554613465769	1.0	0.5341912449718161	8	Q9BVA1,P07437,P23258,P68371,Q13509,Q9BUF5,P04350	7
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.7032318210068349	0.8257113051036058	0.4089678777383816	1.0	0.5755063434153515	2	Q16836	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4354201861076574	0.816287854094978	0.4143355194759073	1.0	0.5771101878414423	11	Q06136,Q53GQ0,Q9Y394,Q8NBN7	4
+Mrp, conserved site [IPR000808]	0.6833436917339738	0.7477307985711822	0.454622550201623	1.0	0.6024852242963257	2	Q8TB37	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.6345556246115696	0.5662306972164224	0.5712369647822635	1.0	0.7039187038305386	2	Q9BTY2	1
+Actin, conserved site [IPR004001]	0.5944686140459985	0.4311751224904173	0.6663410412578867	1.0	0.7708097638279792	2	O96019	1
+Ribosomal protein L30, conserved site [IPR018038]	0.5574891236793161	0.3214669437508317	0.7478565589941499	1.0	0.8288781845284783	2	P18124	1
+Oxysterol-binding protein, conserved site [IPR018494]	0.4553068612074237	0.242348813504021	0.8085098931299914	1.0	0.8793753020895924	4	Q96SU4	1
+Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]	0.4860161591050498	0.1597972556238399	0.8730407859969902	1.0	0.9202321798346654	2	O60573	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.4729645742697406	0.1380853358077655	0.8901729750793161	1.0	0.9327528492603	2	P82675	1
+DnaJ domain, conserved site [IPR018253]	0.3277006891363773	0.1360867222070789	0.8917527240180889	1.0	0.9327528492603	10	Q96KC8	1
+Ribosomal protein L24/L26, conserved site [IPR005825]	0.4425108763207135	0.0966613619513624	0.9229953247902164	1.0	0.9546280259521288	2	Q96A35	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.4749766863537559	0.0964580719328159	0.9231567723493116	1.0	0.9546280259521288	3	P09429,P26583	2
+Calreticulin/calnexin, conserved site [IPR018124]	0.4556453838262205	0.0698582227398	0.9443065052761352	1.0	0.9681612398787623	3	P27824	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.4098819142324554	0.0654831647417878	0.9477893101538096	1.0	0.9681612398787623	2	O43175	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.4083281541330106	0.064303817198392	0.9487283140629366	1.0	0.9681612398787623	2	P10644	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.375505129002181	0.0034534033625717	0.997244588251618	1.0	0.997244588251618	3	Q9BXS5,Q96CW1	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT2", "BCS1L", "BOP1", "BPNT1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR2F", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK1", "RIOK2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM25", "TRIM28", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP33", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACBD5", "ACSL6", "ACTL6A", "AP1M1", "AP2M1", "CANX", "COQ5", "DHRS7", "DNAJC1", "EIF4E2", "FUCA2", "HADH", "HMGB1", "HMGB2", "HMOX2", "HSD17B12", "INA", "KDSR", "LAMP1", "LBR", "LMNA", "LMNB2", "MCL1", "MCM4", "MCM6", "MCM7", "MRPL24", "MRPS5", "NEFL", "NEFM", "NUBPL", "OSBPL9", "PHGDH", "PRKAR1A", "RDH13", "RPL7", "RTN4IP1", "SLC27A2", "STX10", "STX18", "TMX1", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "TUBB", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TXN2", "VAT1", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "GOLD domain [IPR009038]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "GOLD domain [IPR009038]", "1": "Intermediate filament, rod domain [IPR039008]", "2": "Target SNARE coiled-coil homology domain [IPR000727]", "3": "EF-hand domain [IPR002048]", "4": "Immunoglobulin-like domain [IPR007110]", "5": "Tubulin/FtsZ, GTPase domain [IPR003008]", "6": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "7": "Band 7 domain [IPR001107]", "8": "Protein kinase domain [IPR000719]", "9": "Small GTP-binding protein domain [IPR005225]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:221d26a1a628aa8c6f9a71014d902f821eb4bfe5cbaf51b24e2c1cb3d19d5520
+size 339514

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	6	2.239445924744716	0.0251269160614659	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0143692974815416	0.0013899505248691	0.0054453582128303	0.0025675639060761	0.0177300896528831
+GOLD domain [IPR009038]	5	6	1.99746704304318	0.045774471160759	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.01807161676056	1.0	1.0	0.2712176839291556	0.002702316606903
+Phospholipid/glycerol acyltransferase [IPR002123]	3	7	1.966043634823788	0.0492935704236214	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	0.0046413492277287	1.0	1.0	0.3225700131084155	0.0061301079468053

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3220,
+    "annotations_size": 2549,
+    "title": "Average number of proteins per term",
+    "value": 2.1439780306002354
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C289/C289_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,186 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Reticulon [IPR003388]	0.9695273631840792	2.3039107710638027	0.0212276529504111	1.0	0.1300151631040238	4	O75298,O95197,Q9NQC3	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8160055886939918	2.2394459247447154	0.0251269160614659	1.0	0.1376961963496756	6	O15173,O43169	2
+GOLD domain [IPR009038]	0.7629122588674632	1.99746704304318	0.045774471160759	1.0	0.1775698346704035	6	Q9Y3A6,Q9BVK6,Q15363,P49755,Q9H3P7	5
+Phospholipid/glycerol acyltransferase [IPR002123]	0.732210616707043	1.9660436348237875	0.0492935704236214	1.0	0.1838651551949415	7	Q9NUQ2,Q92604,Q8NF37	3
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8072941493741189	1.9466906777355275	0.0515718299206557	1.0	0.1877951349539308	5	P98194,Q9HD20,P16615	3
+Glycosyltransferase 2-like [IPR001173]	0.7369865451274955	1.8769155059841272	0.0605296753068917	1.0	0.203563916913615	6	Q8N4A0	1
+Syntaxin 6, N-terminal [IPR015260]	0.9477936606587908	1.849689367890902	0.0643583337851416	1.0	0.2114924271523018	2	O60499	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.7761176868036196	1.8090372066369973	0.0704452232506032	1.0	0.2220163835996795	5	Q32P28,O15460,P13674	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.7761176868036196	1.8090372066369973	0.0704452232506032	1.0	0.2220163835996795	5	Q32P28,O15460,P13674	3
+Intermediate filament, rod domain [IPR039008]	0.6683826506234056	1.7894264376269786	0.0735461647536634	1.0	0.2237102314523726	8	P08670,Q16352,P07196,P02545,P07197,Q03252	6
+Choline/carnitine acyltransferase domain [IPR039551]	0.9294592914853947	1.7725168778222378	0.0763087961504593	1.0	0.2304146946086615	2	P50416	1
+Prenylcysteine lyase [IPR010795]	0.926662523306402	1.760721269252265	0.0782855910088071	1.0	0.2345206747692139	2	Q8NBM8	1
+p21 activated kinase binding domain [IPR033923]	0.9226227470478549	1.7436730598384909	0.0812161155864332	1.0	0.2376806872902622	2	Q13177	1
+CRIB domain [IPR000095]	0.9226227470478549	1.7436730598384909	0.0812161155864332	1.0	0.2376806872902622	2	Q13177	1
+Acyltransferase, C-terminal domain [IPR032098]	0.9220012430080732	1.7410492274069704	0.0816749499778866	1.0	0.2385847983746688	2	Q9NUQ2	1
+Fatty acid hydroxylase [IPR006694]	0.9160969546302058	1.7161096765328787	0.0861419704985881	1.0	0.2463933816579216	2	Q15800	1
+Ovarian carcinoma immunoreactive antigen domain [IPR009764]	0.9136109384710914	1.7056019688578723	0.0880822125648079	1.0	0.2503027422828267	2	Q9NX40	1
+LEM domain [IPR003887]	0.7003084296911636	1.7037872063728872	0.0884208489650955	1.0	0.2507095930028928	6	P42167,P50402	2
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.907085146053442	1.6780012479888342	0.0933468553834848	1.0	0.2560969648001293	2	P49840	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.903356121814792	1.6622184683899917	0.0964689783095087	1.0	0.2587271169056487	2	Q9NVI7	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.8109406350875148	1.6576805796297562	0.0973819556800892	1.0	0.2596512604901124	4	Q8N4A0	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8999378495960233	1.6477444700462864	0.0994051183779456	1.0	0.2625737271972885	2	Q8N2A8	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8887507768800497	1.6003369848374571	0.1095238462716741	1.0	0.2772356347035723	2	O15254	1
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9303699098538962	1.589209310218714	0.1120131452301218	1.0	0.280411610924313	3	Q9Y282,Q96RQ1	2
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9303699098538962	1.589209310218714	0.1120131452301218	1.0	0.280411610924313	3	Q9Y282,Q96RQ1	2
+Metaxin, glutathione S-transferase domain [IPR033468]	0.929437364003731	1.5855898079409094	0.1128323897512977	1.0	0.2809841507425081	3	Q13505,O75431	2
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.929437364003731	1.5855898079409094	0.1128323897512977	1.0	0.2809841507425081	3	Q13505,O75431	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7870764768746262	1.5574269172404414	0.1193691595219306	1.0	0.2891642598123376	4	P98194,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7870764768746262	1.5574269172404414	0.1193691595219306	1.0	0.2891642598123376	4	P98194,P16615	2
+Intermediate filament head, DNA-binding domain [IPR006821]	0.777985074626863	1.5190791423924557	0.1287425761269269	1.0	0.3034270495917388	4	P08670,P07196,P07197	3
+Ricin B, lectin domain [IPR000772]	0.7082746874986279	1.5037580323808906	0.1326436807623991	1.0	0.3080786264780031	5	Q8N4A0	1
+Tim10-like [IPR004217]	0.9023935343487632	1.4804498732636653	0.1387532286785271	1.0	0.3174883122994305	3	Q9Y5J9,P62072	2
+Thioredoxin domain [IPR013766]	0.4320973926620237	1.4714844135724008	0.1411601596302876	1.0	0.3209788107917958	26	Q9H1E5,Q96J42,Q9H3N1,Q96JJ7	4
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7003369974994661	1.4676009606389595	0.1422126469203672	1.0	0.322796114870896	5	Q8N4Q0,Q8WWV3,Q99536	3
+SUN coiled coil domain 2 [IPR040994]	0.8530142945929009	1.4486682155289214	0.1474302608531172	1.0	0.3283052068307927	2	Q9UH99	1
+Tim44-like domain [IPR007379]	0.8502175264139222	1.4367953634676305	0.1507761482389744	1.0	0.3308230674191573	2	Q9BRJ2	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.7582657450577996	1.4356552312259976	0.1511004701868255	1.0	0.3308230674191573	4	Q96G23,Q15629	2
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.7541638041196903	1.418264882031781	0.1561134454870023	1.0	0.3370902432688711	4	Q8WWV3,Q99536	2
+BRICHOS domain [IPR007084]	0.8424487259167046	1.403822076265982	0.1603718383652825	1.0	0.3414150472970975	2	Q9Y287	1
+Target SNARE coiled-coil homology domain [IPR000727]	0.551086549889743	1.3963950499344322	0.1625955649144146	1.0	0.3428090115523928	10	Q13190,Q12846,P56962,O43752,O60499	5
+EF-hand domain [IPR002048]	0.37576627471664	1.3833760862563478	0.166549579132083	1.0	0.3452901986709589	47	Q9Y680,Q6NUK1,Q8NF37,Q9UBV8,Q9NWM8,P43304,P41208,O75071,Q8IYU8,P80303,Q14257,P14649,Q02818,O75746,O75340,Q9UJS0,Q15293,O43852,Q9BPX6,O95202	20
+Armadillo repeat-containing domain [IPR006911]	0.8331261653200762	1.3642760740916633	0.1724806931600904	1.0	0.3545591023105406	2	Q8N2F6	1
+Immunoglobulin-like domain [IPR007110]	0.5048589988116785	1.340115239740141	0.1802078822169361	1.0	0.3645634061674367	13	P10321,Q08722,P78310,P35613,Q9Y639	5
+Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]	0.822871348663768	1.3208190300464264	0.1865617128757968	1.0	0.3709405663965726	2	Q6BDS2	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.614563743931874	1.2888538519577557	0.1974489000974433	1.0	0.3818643750746457	6	Q6P179,P09960,Q9NZ08	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.614563743931874	1.2888538519577557	0.1974489000974433	1.0	0.3818643750746457	6	Q6P179,P09960,Q9NZ08	3
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8098197638284674	1.2656072888121446	0.205653715255484	1.0	0.3902514649494921	2	P13674	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8051584835301455	1.2459230256021987	0.2127926558642392	1.0	0.3963749325502602	2	Q14011	1
+Rhodanese-like domain [IPR001763]	0.6480017809457572	1.227662022958114	0.2195738683267325	1.0	0.4032376011274072	5	P25325	1
+AMP-dependent synthetase/ligase [IPR000873]	0.5840036081616299	1.2251903263882635	0.2205035184082744	1.0	0.4043622074983392	7	O14975,Q9UKU0	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.7973896830329342	1.213164886794709	0.2250667859442114	1.0	0.410075223282198	2	Q8IWA4	1
+Heat shock chaperonin-binding [IPR006636]	0.6377600564444261	1.1805165416871937	0.2377948353348729	1.0	0.424764565710295	5	P54725	1
+Zinc finger, CHHC-type [IPR012996]	0.8249922287845789	1.1791462308100964	0.2383399523829434	1.0	0.4254401530981253	3	P55795,P31943	2
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.8195115696898052	1.1578981063450922	0.2469056204073281	1.0	0.436554193508722	3	Q5T8D3	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8100714951818365	1.121361883043424	0.2621338541304969	1.0	0.4548193763463295	3	Q32P28,P13674	2
+MCM, AAA-lid domain [IPR041562]	0.5802638132724746	1.120150310561868	0.2626497143906618	1.0	0.4548193763463295	6	Q14566,P33993,P33991	3
+MCM N-terminal domain [IPR027925]	0.5802638132724746	1.120150310561868	0.2626497143906618	1.0	0.4548193763463295	6	Q14566,P33993,P33991	3
+MCM domain [IPR001208]	0.5802638132724746	1.120150310561868	0.2626497143906618	1.0	0.4548193763463295	6	Q14566,P33993,P33991	3
+MCM OB domain [IPR033762]	0.5802638132724746	1.120150310561868	0.2626497143906618	1.0	0.4548193763463295	6	Q14566,P33993,P33991	3
+Peptidase M41 [IPR000642]	0.7697327532629002	1.0972011682689184	0.2725534625861601	1.0	0.46453494054765	2	Q9Y4W6	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6122170304292998	1.062947466314066	0.2878057756516017	1.0	0.4788622207153608	5	O14975,Q9UKU0	2
+FAD dependent oxidoreductase [IPR006076]	0.6691576917332727	1.0570029723498369	0.2905102308954603	1.0	0.4799699545766067	4	Q96CU9,Q9H9P8	2
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.5100198076578604	1.0451317165218563	0.2959620971528682	1.0	0.484837651441299	9	P26440,O15254,Q15067	3
+DDHD domain [IPR004177]	0.7486016159105082	1.009553497501762	0.312709258605393	1.0	0.5019495593105459	2	Q9Y6Y8	1
+GYF domain [IPR003169]	0.7451833436917317	0.9954749945996514	0.3195053000299839	1.0	0.5058503166313224	2	O95400	1
+EB1, C-terminal [IPR004953]	0.7433188315723864	0.9878089714081104	0.3232462129861471	1.0	0.5067371444659834	2	Q15555	1
+EXPERA domain [IPR033118]	0.7426973275326303	0.9852557478072697	0.3244984634576757	1.0	0.5071407623259445	2	Q15125	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7408328154133054	0.9776025483664752	0.3282709364749414	1.0	0.5077186125762759	2	O43390	1
+BSD domain [IPR005607]	0.7405220633934093	0.976327970108495	0.3289019635124015	1.0	0.5077186125762759	2	Q9NW68	1
+ERAP1-like C-terminal domain [IPR024571]	0.6478631737458198	0.9670605062834592	0.3335137871139766	1.0	0.5108934154768788	4	Q6P179,Q9NZ08	2
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.7302672467370965	0.9344281437390431	0.3500830858526935	1.0	0.5250560978642662	2	P00387	1
+NOPS [IPR012975]	0.7556729872552093	0.9132140287645072	0.3611299871183027	1.0	0.535809276580066	3	P23246,Q15233	2
+OCRE domain [IPR041591]	0.7246737103791232	0.911714600861111	0.3619189758076957	1.0	0.5358975121953257	2	P98175	1
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.5024906600249048	0.9065298716532332	0.3646554613465769	1.0	0.5375979010829522	8	Q9BVA1,P07437,P23258,P68371,Q13509,Q9BUF5,P04350	7
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.5024906600249048	0.9065298716532332	0.3646554613465769	1.0	0.5375979010829522	8	Q9BVA1,P07437,P23258,P68371,Q13509,Q9BUF5,P04350	7
+Peptidase M16, C-terminal [IPR007863]	0.521059799190732	0.9005758283598	0.3678138912359847	1.0	0.5391360602418201	7	P22695,Q10713	2
+Peptidase M16, N-terminal [IPR011765]	0.521059799190732	0.9005758283598	0.3678138912359847	1.0	0.5391360602418201	7	P22695,Q10713	2
+Major sperm protein (MSP) domain [IPR000535]	0.7479017718371179	0.8839526511433511	0.3767217732352685	1.0	0.5459146105609435	3	Q8NHP6,Q9P0L0	2
+Immunoglobulin subtype 2 [IPR003598]	0.4805156048601392	0.8784041193584591	0.3797244496728642	1.0	0.5493289569898586	9	P78310,P35613,Q9Y639	3
+Band 7 domain [IPR001107]	0.4926552207184285	0.8534803801145907	0.3933929633402417	1.0	0.556199856995602	8	O94905,Q14254,Q99623,P27105,O75955,P35232	6
+CARG-binding factor, N-terminal [IPR012956]	0.7082038533250532	0.8454909719116498	0.3978367712220634	1.0	0.5579011280828569	2	Q99729	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.7035425730267043	0.8269444258804373	0.4082685613928174	1.0	0.5674354214778035	2	Q15418	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.7032318210068349	0.8257113051036058	0.4089678777383816	1.0	0.5677881919145613	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.7032318210068349	0.8257113051036058	0.4089678777383816	1.0	0.5677881919145613	2	Q16836	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.7304942493005722	0.8190023743337066	0.4127850589360138	1.0	0.571467808759392	3	P16435,P00387	2
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.7304942493005722	0.8190023743337066	0.4127850589360138	1.0	0.571467808759392	3	P16435,P00387	2
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.7304942493005722	0.8190023743337066	0.4127850589360138	1.0	0.571467808759392	3	P16435,P00387	2
+1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]	0.6976382846488571	0.8035886451154245	0.4216345830191184	1.0	0.5774766632171787	2	O15120	1
+FAD-binding domain, PCMH-type [IPR016166]	0.6951522684897198	0.7938023619463652	0.427310497414727	1.0	0.5809143775520743	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.6951522684897198	0.7938023619463652	0.427310497414727	1.0	0.5809143775520743	2	Q15392	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.6789931634555563	0.7309399169519275	0.4648158529773554	1.0	0.6110446669619799	2	P10321	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.6789931634555563	0.7309399169519275	0.4648158529773554	1.0	0.6110446669619799	2	P10321	1
+MHC class I-like antigen recognition-like [IPR011161]	0.6789931634555563	0.7309399169519275	0.4648158529773554	1.0	0.6110446669619799	2	P10321	1
+Immunoglobulin C1-set [IPR003597]	0.6789931634555563	0.7309399169519275	0.4648158529773554	1.0	0.6110446669619799	2	P10321	1
+Histone-binding protein RBBP4, N-terminal [IPR022052]	0.6774394033561297	0.7249683993348339	0.4684714170964732	1.0	0.6142662768410032	2	Q9BQ67	1
+Lamin tail domain [IPR001322]	0.7031395710289129	0.7189599501854353	0.4721655965583315	1.0	0.6165977242457351	3	Q03252,P02545	2
+NAD-dependent epimerase/dehydratase [IPR001509]	0.675264139216913	0.7166311434215255	0.4736017227331115	1.0	0.6178151439338286	2	Q16795	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4159777947163965	0.696399932305755	0.4861784054317275	1.0	0.6220510816164969	11	Q9NWM8	1
+Immunoglobulin subtype [IPR003599]	0.4292961949968391	0.6790575016830055	0.4971014286616952	1.0	0.6300902743205675	10	P78310,P35613,Q9Y639	3
+CBS domain [IPR000644]	0.5273356304414845	0.6786255842477665	0.4973751279924272	1.0	0.6301238574814597	5	Q8NE01,P51798	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.4749325738139343	0.6650014476274827	0.5060495671651639	1.0	0.6348033202283478	7	Q03518,P33897,O75027	3
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6844886540254916	0.6525029150864732	0.5140767929385939	1.0	0.63734520680957	3	Q9ULX6,Q5BKZ1	2
+UBX domain [IPR001012]	0.4782201937714754	0.6229848660536016	0.5332944670317477	1.0	0.6537267729808975	6	Q96CS3,Q92575	2
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.6417029210689963	0.5917833358610971	0.5539956834638202	1.0	0.66072337586337	2	Q9Y305	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.6345556246115696	0.5662306972164224	0.5712369647822635	1.0	0.6736697644278549	2	Q9BTY2	1
+FCP1 homology domain [IPR004274]	0.6375505129002008	0.4935731822058269	0.6216076442833889	1.0	0.7104044509380323	3	Q05D32,Q3ZCQ8	2
+RBM1CTR [IPR012604]	0.6124922311995133	0.4900437359111149	0.6241029505536373	1.0	0.7121617503436966	2	P38159	1
+Patatin-like phospholipase domain [IPR002641]	0.6300901460988457	0.4696415218846049	0.6386111540592787	1.0	0.7228329625653204	3	Q96AD5,Q9NP80	2
+Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]	0.6056556867619746	0.4673349033479376	0.6402602883645909	1.0	0.7243779294457799	2	Q9Y237	1
+SUN domain [IPR012919]	0.6207138238804427	0.4401640608953805	0.659818287264277	1.0	0.74091489613949	3	Q9UH99	1
+Major facilitator superfamily domain [IPR020846]	0.4690725003660246	0.4322879064518004	0.6655321756493859	1.0	0.7445052106774481	5	P11166,Q9H2V7	2
+Class II aldolase/adducin N-terminal [IPR001303]	0.5811062771908138	0.3897165585079953	0.6967461508428923	1.0	0.7728485372056276	2	Q9UEY8	1
+Phosphopantetheine binding ACP domain [IPR009081]	0.568986948415177	0.3538581669701537	0.7234451790883447	1.0	0.7979497020753746	2	O14561	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5649471721566224	0.3422923804058465	0.7321308692005326	1.0	0.8033584096393274	2	Q92945	1
+Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]	0.5574891236793161	0.3214669437508317	0.7478565589941499	1.0	0.8153674588357751	2	P18124	1
+Ribosomal protein L7, eukaryotic/archaeal [IPR035808]	0.5574891236793161	0.3214669437508317	0.7478565589941499	1.0	0.8153674588357751	2	P18124	1
+Ribosomal protein L30, N-terminal [IPR012988]	0.5574891236793161	0.3214669437508317	0.7478565589941499	1.0	0.8153674588357751	2	P18124	1
+Phospholipase/carboxylesterase/thioesterase [IPR003140]	0.5553138595400997	0.3155240701049447	0.752363778411715	1.0	0.8181635115919205	2	O75608	1
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.5546923555003209	0.3138371397848224	0.7536447349541926	1.0	0.8185089175109659	2	O94979	1
+Protein kinase domain [IPR000719]	0.2777694173138332	0.308145224158189	0.7579718304352359	1.0	0.8228578346590358	58	Q15418,P06493,Q96S38,Q13177,Q99640,P49841,Q16539,Q13546,P54646,Q13153,P49840,P24941	12
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.4738805970149203	0.299126613288784	0.7648434409219758	1.0	0.8289055828699473	4	Q8WVV9,P14866,Q9UKA9	3
+Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]	0.5478558110627817	0.2956085079066129	0.7675290755087496	1.0	0.8307565237672199	2	P32322	1
+Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]	0.5478558110627817	0.2956085079066129	0.7675290755087496	1.0	0.8307565237672199	2	P32322	1
+SCP2 sterol-binding domain [IPR003033]	0.5700179492928459	0.2941155407614507	0.768669616003506	1.0	0.8313612351571336	3	P51659	1
+FAST kinase-like protein, subdomain 2 [IPR013579]	0.5469235550031206	0.2931697941131222	0.7693923710222355	1.0	0.8313612351571336	2	Q7L8L6	1
+RAP domain [IPR013584]	0.5469235550031206	0.2931697941131222	0.7693923710222355	1.0	0.8313612351571336	2	Q7L8L6	1
+FAST kinase leucine-rich [IPR010622]	0.5469235550031206	0.2931697941131222	0.7693923710222355	1.0	0.8313612351571336	2	Q7L8L6	1
+ZU5 domain [IPR000906]	0.5379117464263654	0.2701883282130818	0.7870153716250494	1.0	0.8457429098955527	2	Q12955	1
+Dehydrogenase, E1 component [IPR001017]	0.5376009944064742	0.2694152331765591	0.7876101650200253	1.0	0.8460254153544225	2	P08559	1
+Small GTP-binding protein domain [IPR005225]	0.2755664815195444	0.2650032013552335	0.7910069956359795	1.0	0.8489586660530998	50	Q15907,P20339,Q8N442,P62820,P61019,Q9H0U4,P61026,Q13636,Q9Y6B6,Q969Q5,Q9NR31	11
+CTLH/CRA C-terminal to LisH motif domain [IPR024964]	0.534493474207596	0.2617561734171583	0.7935094297555696	1.0	0.8509278655645549	2	Q96S59	1
+CRA domain [IPR013144]	0.534493474207596	0.2617561734171583	0.7935094297555696	1.0	0.8509278655645549	2	Q96S59	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.531075201988827	0.2534831129552676	0.7998949090544629	1.0	0.8570542762420454	2	P42356	1
+Acyl transferase [IPR014043]	0.5298321939092743	0.2505144482049949	0.8021895327969684	1.0	0.859151730714064	2	P49327	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.529210689869498	0.2490380944443731	0.8033313143884189	1.0	0.8596521915936522	2	P22033	1
+Dual specificity protein phosphatase domain [IPR020422]	0.4570043139257445	0.2473571575531629	0.8046318274084487	1.0	0.8599608084126356	4	Q8WUK0	1
+Dual specificity phosphatase, catalytic domain [IPR000340]	0.4570043139257445	0.2473571575531629	0.8046318274084487	1.0	0.8599608084126356	4	Q8WUK0	1
+Tudor domain [IPR002999]	0.3722245606787372	0.2419167889345979	0.8088446407763863	1.0	0.862294014780012	8	Q14739,Q9Y2W6	2
+Syntaxin, N-terminal domain [IPR006011]	0.5474044140503611	0.2373450488495389	0.8123891164135912	1.0	0.8649874092473868	3	Q12846,O15400	2
+Immunoglobulin V-set domain [IPR013106]	0.4470075663044313	0.2184105126210154	0.8271092753671334	1.0	0.8744510754503622	4	P78310	1
+Adenylate kinase, active site lid domain [IPR007862]	0.5111870727159873	0.2085700603918031	0.8347838848735234	1.0	0.8807384613173059	2	Q9UIJ7	1
+Nuclear transport factor 2 domain [IPR002075]	0.4424751243781012	0.2057312683590817	0.8370008323702036	1.0	0.8823470313116828	4	Q9UN86,Q13283,Q9UBU9	3
+Nuclear transport factor 2, eukaryote [IPR018222]	0.4424751243781012	0.2057312683590817	0.8370008323702036	1.0	0.8823470313116828	4	Q9UN86,Q13283,Q9UBU9	3
+Thioesterase domain [IPR006683]	0.5031075201988904	0.1919234012499257	0.8478022066368356	1.0	0.8915213798338671	2	O00154	1
+Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]	0.5006215040397912	0.1869895051359265	0.8516688615060986	1.0	0.8939684220196915	2	P61011	1
+Signal recognition particle SRP54, helical bundle [IPR013822]	0.5006215040397912	0.1869895051359265	0.8516688615060986	1.0	0.8939684220196915	2	P61011	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.5238198876660404	0.1843919736196428	0.8537059659876463	1.0	0.8947765243842558	3	O75396	1
+Longin domain [IPR010908]	0.5238198876660404	0.1843919736196428	0.8537059659876463	1.0	0.8947765243842558	3	O75396	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.348717886149455	0.1837903134216708	0.854177955463761	1.0	0.8949032505043677	9	Q8WUK0,Q99956	2
+Arf GTPase activating protein [IPR001164]	0.4894344313238192	0.1658864801395443	0.8682462873629815	1.0	0.9062898388567732	2	Q8N6T3	1
+SKP1 component, POZ domain [IPR016073]	0.4891236793039238	0.1653259779414314	0.8686874127182129	1.0	0.9063791301754912	2	P63208	1
+Exosome complex component, N-terminal domain [IPR025721]	0.4869484151647142	0.1614413118233524	0.8717458312616244	1.0	0.9091980866963504	2	Q9Y3B2	1
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.4819763828465044	0.1528170171437717	0.8785425776195468	1.0	0.9151634778717714	2	Q9NXV2	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.4729645742697406	0.1380853358077655	0.8901729750793161	1.0	0.9240447508437106	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.4729645742697406	0.1380853358077655	0.8901729750793161	1.0	0.9240447508437106	2	P82675	1
+Amine oxidase [IPR002937]	0.4676817899316509	0.1299843158987603	0.8965788355071063	1.0	0.9280909111174954	2	Q8NB78	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.342848717371739	0.1175329955203276	0.9064376985888208	1.0	0.9354290257906496	8	Q8IWA4,O60313	2
+Dynamin, N-terminal [IPR045063]	0.342848717371739	0.1175329955203276	0.9064376985888208	1.0	0.9354290257906496	8	Q8IWA4,O60313	2
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.458669981354892	0.1170642386545125	0.9068091482597876	1.0	0.9354336377637388	2	Q9NP81	1
+Domain of unknown function DUF4217 [IPR025313]	0.4805719614547803	0.1050172387225818	0.9163621298355148	1.0	0.9431963846996	3	Q9NVP1,Q8NHQ9	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.4008084577114352	0.1032076913304222	0.9177981357138107	1.0	0.9440950153085164	4	O60749,Q9UNH7,Q9Y5X3	3
+Ribosomal protein L26/L24, KOW domain [IPR041988]	0.4425108763207135	0.0966613619513624	0.9229953247902164	1.0	0.9486754366492992	2	Q96A35	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.4192044748291047	0.073113570205534	0.9417157430981632	1.0	0.9640294896213728	2	Q15120	1
+Histidine kinase domain [IPR005467]	0.4192044748291047	0.073113570205534	0.9417157430981632	1.0	0.9640294896213728	2	Q15120	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.4083281541330106	0.064303817198392	0.9487283140629366	1.0	0.9696505503393846	2	P10644	1
+Brix domain [IPR007109]	0.3781094527363089	0.0586740379482689	0.9532117384181628	1.0	0.973842373237634	4	Q9NQ55,Q9H7B2,Q9H9Y2	3
+ENTH  domain [IPR013809]	0.4454460677650012	0.0576380612465861	0.9540369315627448	1.0	0.973848006545399	3	Q14677,Q9Y6I3	2
+Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]	0.3974518334369288	0.0567486034719497	0.954745456397392	1.0	0.973848006545399	2	P21399	1
+Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]	0.3974518334369288	0.0567486034719497	0.954745456397392	1.0	0.973848006545399	2	P21399	1
+FAD/NAD(P)-binding domain [IPR023753]	0.3365673071759308	0.0542031428710198	0.956773316718718	1.0	0.9747037225692626	6	O95831	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.3896830329397273	0.0520620069394559	0.9584792859596348	1.0	0.9749256583843212	2	Q15477	1
+rRNA-processing arch domain [IPR025696]	0.3896830329397273	0.0520620069394559	0.9584792859596348	1.0	0.9749256583843212	2	Q15477	1
+Ribosomal protein S10 domain [IPR027486]	0.4389182468138051	0.0504527149539845	0.959761629382148	1.0	0.9754515124781082	3	P60866,P82664	2
+BAG domain [IPR003103]	0.363184079601983	0.0338579269912286	0.97299044333386	1.0	0.9853606039165708	4	O95429,O95817,Q9UL15	3
+Zinc finger, TFIIB-type [IPR013137]	0.3343691733996381	0.0321161637729687	0.9743794132327516	1.0	0.9863753472320428	2	P29083	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.3042262274704908	0.0278984834742551	0.9777431179862156	1.0	0.9886026210816594	2	Q9BSJ2	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.3042262274704908	0.0278984834742551	0.9777431179862156	1.0	0.9886026210816594	2	Q9BSJ2	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.4065899906745531	0.0217075173232625	0.9826812672299756	1.0	0.9928079865910456	3	Q9UL46,P61289	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.4065899906745531	0.0217075173232625	0.9826812672299756	1.0	0.9928079865910456	3	Q9UL46,P61289	2
+Cyclin, N-terminal [IPR006671]	0.3832763444202747	0.007265080100102	0.9942033557476664	1.0	1.0	3	P14635,O95067	2
+Cyclin, C-terminal domain [IPR004367]	0.3832763444202747	0.007265080100102	0.9942033557476664	1.0	1.0	3	P14635,O95067	2
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.38078955548649	0.0059948015744371	0.995216869027775	1.0	1.0	3	Q4J6C6,P13798	2
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.3404850746268575	0.0027465268308299	0.9978085914009658	1.0	1.0	4	P38606,P06576,P21281	3
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.3404850746268575	0.0027465268308299	0.9978085914009658	1.0	1.0	4	P38606,P06576,P21281	3
+Ribosomal protein L18e/L15P [IPR021131]	0.3708423997513265	0.0013824494153075	0.9988969653067824	1.0	1.0	3	P46776,Q9P015	2

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]"}