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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Activation of ampk downstream of nmdars 0.8991006958542695 2.841985793972915 0.0044833489285414 0.998008577597498 0.7290776765265655 8 P54646,Q13509 2
Carboxyterminal post translational modifications of tubulin 0.9209624558060452 2.7391244529998997 0.0061603049252996 0.9998068862805416 0.7290776765265655 7 Q13509,Q9BVA1 2
Gap junction assembly 0.9118070312765104 2.5161735742048275 0.0118636739776856 0.9999999329279744 0.7290776765265655 6 Q13509 1
Transport of connexons to the plasma membrane 0.9118070312765104 2.5161735742048275 0.0118636739776856 0.9999999329279744 0.7290776765265655 6 Q13509 1
Defects in biotin btn metabolism 0.9029476286185332 2.479783094902556 0.0131462326410045 0.9999999888857568 0.7290776765265655 6 Q96RQ3,P05165,P11498 3
Biotin transport and metabolism 0.8575012070578802 2.469463146969889 0.0135315955775228 0.9999999935267728 0.7290776765265655 7 Q96RQ3,P05165,P11498 3
Maturation of sars cov 2 spike protein 0.731449621637053 2.33170256559105 0.0197163437616298 0.9999999999989264 0.7290776765265655 11 Q13724 1
Pkmts methylate histone lysines 0.7279390808795989 2.314054771418136 0.0206647179265893 0.9999999999997188 0.7290776765265655 11 Q9H7B4,Q03164 2
Branched chain amino acid catabolism 0.6596495166981968 2.2600679916290676 0.0238170313380432 0.9999999999999968 0.7290776765265655 14 Q96H78 1
Signaling by fgfr1 in disease 0.7472620249511954 2.2345722662170395 0.0254454432817605 0.9999999999999996 0.7290776765265655 9 O95684,O95429,P40763,Q16630 4
Fgfr1 mutant receptor activation 0.7472620249511954 2.2345722662170395 0.0254454432817605 0.9999999999999996 0.7290776765265655 9 O95684,O95429,P40763,Q16630 4
Formation of tubulin folding intermediates by cct tric 0.6515110013911789 2.21445276357248 0.0267976486995646 1.0 0.7290776765265655 14 Q13509 1
Defects in vitamin and cofactor metabolism 0.716500996082558 2.1676769852250852 0.0301832717436343 1.0 0.7290776765265655 10 Q96RQ3,P05165,P11498 3
Gap junction trafficking and regulation 0.6788207490318318 2.155928256190069 0.0310892676929972 1.0 0.7290776765265655 12 Q13509 1
Formation of the cornified envelope 0.8624761678630957 2.130147225997406 0.0331594604328022 1.0 0.7290776765265655 5 Q14126,P15924 2
Keratinization 0.8624761678630957 2.130147225997406 0.0331594604328022 1.0 0.7290776765265655 5 Q14126,P15924 2
Phase i functionalization of compounds 0.6498978040204637 2.099168194304096 0.0358020766735285 1.0 0.7290776765265655 13 P30837,P07099 2
Degradation of the extracellular matrix 0.7404700547254393 1.9497558837802025 0.0512052220380698 1.0 0.7290776765265655 7 P17655 1
Dna damage reversal 0.8184984370566348 1.9482114372334995 0.0513896688563253 1.0 0.7290776765265655 5 P16455,Q6P6C2 2
Rhobtb3 atpase cycle 0.8498417125145596 1.90553417457768 0.0567106694947177 1.0 0.7694859468695029 4 O60664,P51151 2
Signaling by cytosolic fgfr1 fusion mutants 0.7291866806778017 1.898165730572753 0.0576742536082526 1.0 0.7725493941640531 7 O95684,P40763,Q16630 3
Intraflagellar transport 0.6250462442984903 1.8680770450532704 0.0617513326474101 1.0 0.7983359566712558 12 Q13509 1
Lipophagy 0.8380674237840774 1.8580985876124996 0.063155015380989 1.0 0.7983359566712558 4 P54646 1
Polo like kinase mediated events 0.832697201017804 1.8364018871330836 0.0662982406854362 1.0 0.8145753718278728 4 O95067,P14635,Q99640 3
Rho gtpases activate iqgaps 0.6104269389626132 1.7885474417530742 0.0736877287359611 1.0 0.852231266706903 12 Q13509,P35222,Q9BVA1 3
Heme biosynthesis 0.7801923616780853 1.7872760411443829 0.0738928843965522 1.0 0.852231266706903 5 P22830 1
E2f mediated regulation of dna replication 0.6396510561501239 1.7794053734729611 0.0751733261422227 1.0 0.8527859293511167 10 Q14181,Q9Y619,P14635,Q9UBD5 4
Transport of vitamins nucleosides and related molecules 0.6914334686725884 1.7238437361171497 0.0847360566880952 1.0 0.9125302900464484 7 P12235,O00400 2
Hdms demethylate histones 0.7239632554112715 1.7131454572842306 0.0866857829696938 1.0 0.9125302900464484 6 Q8NB78 1
Dna replication initiation 0.6542370830543927 1.7108654795187053 0.0871059484664726 1.0 0.9125302900464484 8 Q14181,Q9NR33,Q9NRF9 3
Suppression of apoptosis 0.7958174804209543 1.6864298340762518 0.0917130391358804 1.0 0.9179426524339752 4 P23246,P49840 2
Assembly and cell surface presentation of nmda receptors 0.5871791657275587 1.661096752656298 0.0966940165689214 1.0 0.9358357967229876 12 Q14168,Q13509,Q9BVA1 3
Post chaperonin tubulin folding pathway 0.5989394447961485 1.6434851110573931 0.1002826033900001 1.0 0.9571801592535188 11 P36404,Q15813,Q13509,Q9BVA1 4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.9089414212556264 1.6394831494629705 0.1011126771976052 1.0 0.9584927756266136 3 P11802 1
Translation of sars cov 2 structural proteins 0.5731969243368272 1.63476575404957 0.1020981623664327 1.0 0.9612507259533534 18 P78362,Q13724,P61803,P49840,Q96SB4 5
Maturation of sars cov 2 nucleoprotein 0.7033743768700091 1.6215173653000303 0.1049067288147083 1.0 0.9735778246463628 6 P49840,Q96SB4,P78362,Q99873 4
Piwi interacting rna pirna biogenesis 0.5913422341325697 1.6028208954127934 0.1089742021918787 1.0 0.9902024601808024 11 Q8N2A8,O15514,P24928 3
Signaling by pdgfr in disease 0.7305122494431933 1.5756154548802956 0.1151144522155223 1.0 0.9902024601808024 5 P40763,P62993,Q6UN15,O43815 4
Cyclin a b1 b2 associated events during g2 m transition 0.581533286579579 1.550176431940402 0.1210991749523775 1.0 0.9902024601808024 11 O95067,P14635,Q99640 3
Collagen formation 0.5951473131526205 1.5487246102974104 0.121447935181707 1.0 0.9902024601808024 10 Q32P28,Q15149,Q02809,O60568 4
Microrna mirna biogenesis 0.5794135832230238 1.5387806112659714 0.123857864795831 1.0 1.0 11 P19388,Q9HAV4,P24928,P52434,P62875,Q8WYQ5,O15514 7
Fceri mediated ca 2 mobilization 0.7584420940379681 1.532946531831351 0.1252890295218143 1.0 1.0 4 O43865,P62993 2
Cyclin d associated events in g1 0.5905283838167213 1.5245924647871094 0.1273607780236494 1.0 1.0 10 P11802,Q00534,Q13616 3
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.751423668766061 1.5039908886981244 0.1325837127644276 1.0 1.0 4 P12235 1
Map2k and mapk activation 0.5722907391822932 1.5004411338379773 0.1335001711509638 1.0 1.0 11 Q02750,P36507,P28482,P31946,P30086 5
G2 m dna replication checkpoint 0.7487939868551016 1.4931327302391213 0.1354024464810677 1.0 1.0 4 O95067,Q99640 2
Hdacs deacetylate histones 0.5532076084289863 1.473071551593412 0.1407317433984016 1.0 1.0 12 Q14839,O00422,O94776,Q13330,O60341,Q13547,Q16576,Q9BTC8 8
Transcriptional regulation of granulopoiesis 0.637834546622082 1.4725196660523594 0.1408806003638005 1.0 1.0 7 P11802,Q03164 2
Extra nuclear estrogen signaling 0.592304659395667 1.4663561759653247 0.142551278761486 1.0 1.0 9 P28482,P31751,P04792,Q99873 4
Condensation of prometaphase chromosomes 0.5782633583219093 1.4603764628007734 0.1441866379323919 1.0 1.0 10 O95067,P67870,P14635,P19784 4
Purine ribonucleoside monophosphate biosynthesis 0.5893463095775257 1.4512646421784297 0.1467061829064451 1.0 1.0 9 Q06203,P31939,P30520,O15067,P30566,P49915 6
Vitamin b5 pantothenate metabolism 0.6986636678810583 1.4385926397596216 0.1502659729367081 1.0 1.0 5 Q9NRN7,Q13057 2
Kinesins 0.5418409379475518 1.420465175195657 0.1554723001304085 1.0 1.0 19 Q02241,Q13509,Q9NSK0,Q9BVA1 4
Synthesis of udp n acetyl glucosamine 0.694423247259806 1.4202945374502725 0.1555219508082026 1.0 1.0 5 O95394 1
Signaling by kit in disease 0.7302798982188051 1.4165691442439066 0.1566089351401349 1.0 1.0 4 P62993,P40763,P07948 3
Antimicrobial peptides 0.846740858505554 1.4069813116212897 0.1594329304633872 1.0 1.0 3 P35030,Q96JM3 2
E2f enabled inhibition of pre replication complex formation 0.7137513213562383 1.3480891711300007 0.1776297039287788 1.0 1.0 4 Q9Y619,Q9UBD5 2
Aggrephagy 0.5119566237793047 1.3390360391246494 0.1805589408004877 1.0 1.0 16 Q13509,Q9BVA1 2
Growth hormone receptor signaling 0.6299807069082004 1.2914637473033237 0.19654291815583 1.0 1.0 6 P28482,P40763,P07948 3
Apoptotic cleavage of cell adhesion proteins 0.6642357145865054 1.2898297842570452 0.1971097642590966 1.0 1.0 5 P15924 1
Response of mtb to phagocytosis 0.519233381549782 1.2837535869536305 0.1992281879963324 1.0 1.0 12 P23246,O14964,P49840,P52294,P28482 5
Infection with mycobacterium tuberculosis 0.519233381549782 1.2837535869536305 0.1992281879963324 1.0 1.0 12 P23246,O14964,P49840,P52294,P28482 5
Oncogene induced senescence 0.6272365782269437 1.2790704870974663 0.200872235321488 1.0 1.0 6 P11802,P28482,Q00534 3
Cell cycle 0.2588724290465587 1.273687159806171 0.2027743087992355 1.0 1.0 300 P28070,P31751,P53350,Q96EA4,Q15003,Q15691,P35250,O96017,Q13509,Q9NRF9,Q16576,Q14997,Q13472,P49642,Q9UQ84,P49736,Q99436,Q9BUR4,P49721,Q9BVA1,Q14203,P30260,O95684,O75122,P43034,O43264,Q7Z460,Q9NWV8,Q9UN37,P31946,P20618,P00374,P42166,P11802,Q8WYP5,Q99640,Q9UPP1,Q14181,P02545,O94901,P07948,O43237,P25786,P42677,P62140,Q2NKX8,O15514,Q86Y07,Q96IY1,O00743,O14974,Q9HBM1,P49841,Q9H1A4,Q8IXJ6,Q9UH99,Q00534,P67870,P19784,Q8NFH3,P24928,O95067,P04818,Q02241,Q99567,O43805,P37198,Q9BSJ2,Q9UBD5,Q9Y619,Q12888,Q13547,Q13616,Q15154,Q9NR33,P14635,P52434,P28482,Q9NRG9,O43684,O60566,Q8WVM7 82
Signaling by fgfr3 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Signaling by fgfr1 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Negative regulation of fgfr4 signaling 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Signaling by fgfr4 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Negative regulation of fgfr3 signaling 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Spry regulation of fgf signaling 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Negative regulation of fgfr1 signaling 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Negative regulation of fgfr2 signaling 0.6600503541697673 1.2717298717266374 0.2034691132390902 1.0 1.0 5 P28482,P62993 2
Signaling by fgfr in disease 0.5203838831934574 1.264790989120313 0.2059462623879575 1.0 1.0 20 O95684,P40763,P24928,O95429,O15514,Q16630 6
Cholesterol biosynthesis 0.5127835629541174 1.250602600058092 0.2110795015332605 1.0 1.0 19 Q15125,Q15392,Q15800 3
Signaling by alk 0.6902259648606933 1.2505496484298635 0.2110988307379404 1.0 1.0 4 P40763 1
Stat3 nuclear events downstream of alk signaling 0.6902259648606933 1.2505496484298635 0.2110988307379404 1.0 1.0 4 P40763 1
Collagen biosynthesis and modifying enzymes 0.5460314925389869 1.2295690450378436 0.2188585276907861 1.0 1.0 9 Q32P28,Q02809,O60568 3
Regulation of tp53 activity through acetylation 0.5181286655019935 1.2075391560542297 0.2272245749773063 1.0 1.0 11 Q8TBX8,P31751,O94776,Q13526,Q16576,Q13547 6
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4990211175918143 1.2005546918837569 0.2299239852785946 1.0 1.0 18 Q13509 1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.7914149443561113 1.1996494710938337 0.2302755047272233 1.0 1.0 3 Q7Z434,Q13546 2
Foxo mediated transcription 0.5401185354348101 1.199271678779222 0.230422323711269 1.0 1.0 9 P31946,P31751,Q13547 3
Carnitine metabolism 0.608910099972308 1.196328661369798 0.2315683282345464 1.0 1.0 6 O43772,P54646 2
Role of abl in robo slit signaling 0.6768603932143491 1.1951735037088482 0.2320192484699297 1.0 1.0 4 Q7Z460 1
Negative feedback regulation of mapk pathway 0.6761955981085143 1.192421023997268 0.2330962007044013 1.0 1.0 4 P28482,Q02750 2
Beta oxidation of very long chain fatty acids 0.6059815394699583 1.1831170978129075 0.236762742542532 1.0 1.0 6 Q15067,P09110 2
Egfr downregulation 0.5478798559273391 1.1831107578544733 0.2367652548498386 1.0 1.0 8 O14964,Q92783,P62993 3
Activation of nima kinases nek9 nek6 nek7 0.6389903219914141 1.1807105513394471 0.2377177284644935 1.0 1.0 5 O95067,P14635 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5457929912927402 1.172691510000719 0.2409195372674086 1.0 1.0 8 Q15067,P09110 2
Synthesis of very long chain fatty acyl coas 0.5347493182815053 1.1717721376255723 0.2412885518536844 1.0 1.0 9 Q9UKU0 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.7825119236883864 1.166385121971693 0.2434587711464897 1.0 1.0 3 O43865,P62993 2
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6008981866488872 1.1601964701015997 0.245968823835059 1.0 1.0 6 Q14181 1
Metabolism of folate and pterines 0.5322826441118482 1.1591440728037523 0.2463974636935133 1.0 1.0 9 P34896 1
Signaling by erythropoietin 0.7794523869692036 1.1549664635508936 0.2481041601082378 1.0 1.0 3 P62993 1
Erythropoietin activates ras 0.7794523869692036 1.1549664635508936 0.2481041601082378 1.0 1.0 3 P62993 1
Signal attenuation 0.7746087725900224 1.1369045090043564 0.2555782069776686 1.0 1.0 3 P62993 1
Met activates ras signaling 0.6604038085227714 1.1271189486654785 0.2596921928512445 1.0 1.0 4 Q96S59,P62993 2
N glycan trimming in the er and calnexin calreticulin cycle 0.4759954429190345 1.1270182754544629 0.259734754200885 1.0 1.0 16 Q13438,Q13724,Q14165 3
Erks are inactivated 0.5647274181797578 1.1260804284374852 0.2601314773884042 1.0 1.0 7 P51452 1
Ncam signaling for neurite out growth 0.6257055494707664 1.1234129714637988 0.2612621432651725 1.0 1.0 5 P28482,P62993 2
Signaling by csf3 g csf 0.5327181182600778 1.1074735621753151 0.2680892365742524 1.0 1.0 8 P40763,Q15369,Q06124,P07948,P62993 5
Mitochondrial trna aminoacylation 0.4614599089964216 1.103959084026291 0.2696108869488132 1.0 1.0 14 Q5ST30,Q9BW92,Q15046 3
Smad2 smad3 smad4 heterotrimer regulates transcription 0.7654728804541714 1.10289379886284 0.2700732874971532 1.0 1.0 3 Q13547 1
Regulation of pyruvate dehydrogenase pdh complex 0.5205429054751882 1.099113557713526 0.2717185369694641 1.0 1.0 9 P08559,Q8NCN5 2
Regulation of runx1 expression and activity 0.7624801271859977 1.0917707409017694 0.2749338826601646 1.0 1.0 3 Q00534,Q9HCE1 2
Signaling by scf kit 0.584738801377206 1.0874761970871578 0.276826412504211 1.0 1.0 6 P40763,P62993,Q06124,P07948 4
Pyruvate metabolism 0.4684050121256268 1.082510093783607 0.279025932726201 1.0 1.0 16 P08559,Q8NCN5,P35613 3
Nucleotide biosynthesis 0.4800715728761753 1.0658170077692466 0.2865063710445459 1.0 1.0 12 Q06203,P31939,P30520,O15067,P30566,P49915,P11172 7
Signaling by moderate kinase activity braf mutants 0.4796744826789246 1.063618478272758 0.2875015680801513 1.0 1.0 12 Q02750,P31946,P28482,P30086 4
Regulation of localization of foxo transcription factors 0.6093346499889184 1.053040600898904 0.2923223844252034 1.0 1.0 5 P31751 1
Fatty acyl coa biosynthesis 0.4574523802736341 1.0491140394748126 0.2941256352239192 1.0 1.0 15 Q13085,Q9UKU0 2
Mapk1 erk2 activation 0.7494435612082652 1.043440904383003 0.2967441372052102 1.0 1.0 3 P28482,Q06124 2
Synthesis of pi 0.967577876668784 1.0425881631535263 0.2971390737585131 1.0 1.0 2 O96017 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.4758240329585545 1.0423192505505745 0.2972636901577647 1.0 1.0 12 O94826,Q13546,Q7Z434,Q14258,Q86UT6,Q13526 6
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5453910204712239 1.0347762939292244 0.3007733963429047 1.0 1.0 7 P46939,Q9NR77,P11047,P51532,P46937 5
Negative regulation of nmda receptor mediated neuronal transmission 0.5712921705919722 1.0272049484444168 0.3043239684872953 1.0 1.0 6 Q14168,P07196,P35609,P49593,Q13555 5
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4838186374037764 1.0225397890135668 0.3065254906573798 1.0 1.0 11 O15047,Q03164,Q13547,Q99873 4
Rna polymerase i transcription initiation 0.478053180381627 1.0197841101980814 0.3078308607591911 1.0 1.0 20 Q14839,O15160,P19388,O94776,P19447,P17480,P52434,P62875,Q16576,Q13547,Q9BTC8 11
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.7425243686566556 1.0178820867403258 0.3087339955281227 1.0 1.0 3 P40763 1
Interleukin 2 family signaling 0.7425243686566556 1.0178820867403258 0.3087339955281227 1.0 1.0 3 P40763 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.4567157661618902 1.014283627780309 0.3104474340201644 1.0 1.0 16 Q03518,Q9NZ08 2
Sealing of the nuclear envelope ne by escrt iii 0.4793107112895893 0.998399219247158 0.3180858120695162 1.0 1.0 11 Q13509 1
Tysnd1 cleaves peroxisomal proteins 0.5627226685566289 0.988952762092136 0.3226862540437425 1.0 1.0 6 P09110 1
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.4659176048886059 0.9877037309824944 0.3232977667304948 1.0 1.0 12 Q96GM5,P67870,P19784 3
Glutathione synthesis and recycling 0.561369459747605 0.9829257534286996 0.3256439817509087 1.0 1.0 6 Q96KP4,O75223 2
Association of tric cct with target proteins during biosynthesis 0.4652598394671985 0.9752161949461138 0.329453030473704 1.0 1.0 19 O95302,Q9BUR4,P40763 3
Polb dependent long patch base excision repair 0.5591595540914507 0.9730916628986076 0.3305077472414885 1.0 1.0 6 P09874,P18858,Q86W56 3
Interleukin 6 family signaling 0.7300476947535623 0.9719861584699024 0.331057434603859 1.0 1.0 3 P40763,Q06124 2
Interleukin 20 family signaling 0.7300476947535623 0.9719861584699024 0.331057434603859 1.0 1.0 3 P40763,Q06124 2
Interleukin 6 signaling 0.7300476947535623 0.9719861584699024 0.331057434603859 1.0 1.0 3 P40763,Q06124 2
Negative regulators of ddx58 ifih1 signaling 0.5301917156616746 0.9634366518103012 0.3353284404159433 1.0 1.0 7 Q13526,Q7Z434,Q86UT6 3
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4826420030470702 0.9587291821419954 0.3376951933092147 1.0 1.0 10 P67870 1
Cell junction organization 0.4462193165725122 0.9534466067407428 0.3403638367287407 1.0 1.0 16 Q13418,O60716,P35222,Q15149,P14923 5
Signaling by egfr 0.4708396695683574 0.9531964691760708 0.3404905350319396 1.0 1.0 11 O14964,Q9Y6I3,Q13685,Q92783,P62993 5
Hiv transcription initiation 0.4403179076000006 0.9492157264060882 0.3425109046860664 1.0 1.0 15 P24928,P29083,P19447,O15514,Q92804,P52434,P62875,Q12962 8
Activation of the pre replicative complex 0.4654252244935693 0.9477356033559188 0.3432640710212498 1.0 1.0 20 Q14181,Q9NR33,P49642,Q9NRF9,Q9Y619,Q9UBD5 6
Mapk3 erk1 activation 0.6155564605811039 0.9432407334053948 0.3455577827674556 1.0 1.0 4 Q02750,Q06124 2
Adherens junctions interactions 0.524594640691905 0.9372974058029836 0.348605597016645 1.0 1.0 7 O60716,P55196,P14923,P35222 4
Estrogen dependent nuclear events downstream of esr membrane signaling 0.6136035991405401 0.9353150187349264 0.3496259775953554 1.0 1.0 4 P28482 1
Rnd3 gtpase cycle 0.4429286993177204 0.9344760267434872 0.3500583965780168 1.0 1.0 16 P15924 1
Metabolism of cofactors 0.5234055681831729 0.9317548474453085 0.351463234235513 1.0 1.0 7 P00374,Q5HYK3 2
Resolution of d loop structures 0.5450698061284596 0.9106714935207167 0.3624684883616857 1.0 1.0 6 Q13472 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5450698061284596 0.9106714935207167 0.3624684883616857 1.0 1.0 6 Q13472 1
Negative regulation of met activity 0.4923107925398665 0.9074945376899176 0.3641453367329923 1.0 1.0 8 Q92783,P62993 2
Listeria monocytogenes entry into host cells 0.4889971578650741 0.8912723655247003 0.3727830701633698 1.0 1.0 8 O14964,Q92783,P62993,P35222 4
Flt3 signaling 0.602626720172089 0.8909382044297515 0.3729623230402414 1.0 1.0 4 P31751,P62993 2
Long term potentiation 0.5711104040725247 0.8905164063162596 0.3731886629455259 1.0 1.0 5 Q14168,P07196,P35609,Q13555 4
Ras activation upon ca2 influx through nmda receptor 0.5711104040725247 0.8905164063162596 0.3731886629455259 1.0 1.0 5 Q14168,P07196,P35609,Q13555 4
Unblocking of nmda receptors glutamate binding and activation 0.5711104040725247 0.8905164063162596 0.3731886629455259 1.0 1.0 5 Q14168,P07196,P35609,Q13555 4
Mitochondrial fatty acid beta oxidation 0.4338165413179605 0.8822426250590746 0.3776456159219765 1.0 1.0 16 P49748,P05165 2
Phosphorylation of emi1 0.7049284578696255 0.8805081829085359 0.3785840742305972 1.0 1.0 3 P53350,P14635 2
Traf6 mediated nf kb activation 0.7046104928457767 0.8793595315590805 0.3792063669748544 1.0 1.0 3 Q7Z434,Q14258 2
Polymerase switching 0.4330849386430827 0.8698785903492271 0.3843667567333124 1.0 1.0 13 Q14181,P35249,P35250,P49642,P28340,P12004,P40937,P35251,Q9Y2S7 9
Wnt mediated activation of dvl 0.9144945963127784 0.8657157495258988 0.386646060968562 1.0 1.0 2 P67870 1
Nucleotide salvage 0.4822931855777894 0.8585691861229724 0.3905782445169317 1.0 1.0 8 Q9BZX2 1
Crmps in sema3a signaling 0.5923425647687064 0.8496614263631049 0.395513350038279 1.0 1.0 4 P49841 1
Regulation of tp53 activity through phosphorylation 0.4940981478977727 0.8468832720396432 0.3970601872887669 1.0 1.0 30 P67870,Q13472,O96017,Q9UQ84,P19784,Q92804,P54646,Q12962 8
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.5898446105870039 0.8396844777736299 0.401085319370642 1.0 1.0 4 Q13547,P04179 2
Uptake and function of anthrax toxins 0.6924065108968762 0.8354763174987551 0.4034495757111305 1.0 1.0 3 Q02750 1
Citric acid cycle tca cycle 0.4443634031294642 0.8294358675080361 0.4068578126080984 1.0 1.0 20 P53597,O43837,P36957,P23368,P31040,P51553,Q99643,Q6P587,P48735 9
Slc mediated transmembrane transport 0.4522804235054565 0.8198784706051594 0.4122853912159274 1.0 1.0 22 P12235,P35613,Q70HW3,O00400 4
Interleukin 15 signaling 0.8998728544183066 0.8181641643542702 0.4132634545308549 1.0 1.0 2 P40763 1
Ksrp khsrp binds and destabilizes mrna 0.4230648373344213 0.8143882998565476 0.4154225392010358 1.0 1.0 13 O95453,Q06265,Q9NQT5,Q96B26 4
Runx2 regulates osteoblast differentiation 0.6825480913706924 0.80034290359605 0.4235121518680327 1.0 1.0 3 P28482 1
Interleukin 7 signaling 0.8935155753337543 0.7976835890614625 0.425054129628831 1.0 1.0 2 P40763 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.4601180399869034 0.7948691531418116 0.4266896194670484 1.0 1.0 9 P14635,O96017 2
Sulfur amino acid metabolism 0.4400560203818393 0.7914028072234205 0.4287089723594115 1.0 1.0 11 Q9BV57,P25325,P32929,Q99757,Q99707,P23526,Q13126 7
Inlb mediated entry of listeria monocytogenes into host cell 0.5167086966414298 0.7869370816439797 0.431318698889849 1.0 1.0 6 Q92783,P62993 2
Methionine salvage pathway 0.6779014308426032 0.7838907895957532 0.4331041946317346 1.0 1.0 3 Q13126,Q9BV57 2
Mismatch repair 0.448258676698599 0.7828176922032201 0.4337341766021167 1.0 1.0 10 P43246,P52701,Q9UQ84,P28340,Q9Y2S7 5
Signaling by pdgf 0.5157297519535793 0.7827230685712455 0.4337897525862182 1.0 1.0 6 Q06124,P62993,P40763 3
Downstream signal transduction 0.5157297519535793 0.7827230685712455 0.4337897525862182 1.0 1.0 6 Q06124,P62993,P40763 3
Ptk6 regulates proteins involved in rna processing 0.8884297520661151 0.7813899752082782 0.4345731653973499 1.0 1.0 2 Q07666 1
Runx2 regulates bone development 0.5747455470737762 0.7798392513171766 0.4354854993948889 1.0 1.0 4 P28482,P46937,Q96PK6 3
Fanconi anemia pathway 0.5132379652373754 0.7720166906615115 0.4401045420919383 1.0 1.0 6 Q9BXW9 1
Coenzyme a biosynthesis 0.6736467702194264 0.7688911499714804 0.4419579316371775 1.0 1.0 3 Q13057 1
Interferon gamma signaling 0.4344664281819972 0.7625781589275243 0.4457150142698061 1.0 1.0 11 Q06124,P29372,Q14258,P19474,Q12899 5
G1 s specific transcription 0.4432071661732277 0.7574764333074586 0.4487644796292509 1.0 1.0 10 P00374,Q9Y619,P04818 3
Interleukin 27 signaling 0.6698926939237466 0.7557097869253973 0.4498232149207779 1.0 1.0 3 P40763 1
Interleukin 35 signalling 0.6698926939237466 0.7557097869253973 0.4498232149207779 1.0 1.0 3 P40763 1
Diseases of dna repair 0.4415194383567618 0.7490457721915955 0.4538296177900454 1.0 1.0 10 Q13472 1
Raf independent mapk1 3 activation 0.4831311764648907 0.7469876850900659 0.4550709945032873 1.0 1.0 7 P28482,Q02750,Q06124,P36507 4
Protein folding 0.5004079771011827 0.7451481430637634 0.4561821678882172 1.0 1.0 36 P36404,P67870,Q13509,P40763,O95302,Q9H0D6,Q9BUR4,Q9BVA1 8
Apoptotic cleavage of cellular proteins 0.4110055495315499 0.7266594497951822 0.4674345999602884 1.0 1.0 17 Q14126,Q15149,P15924,Q9P289 4
Atf4 activates genes in response to endoplasmic reticulum stress 0.4163335373079482 0.7209952359543305 0.4709124458671727 1.0 1.0 12 O95453,Q06265,Q9NQT5,Q96B26 4
Interleukin 37 signaling 0.6596222956920058 0.7199204854243473 0.4715739542845738 1.0 1.0 3 P40763 1
Advanced glycosylation endproduct receptor signaling 0.477080475152016 0.71987168896918 0.4716040006327697 1.0 1.0 7 P09429,P39656,P52907,P28482,P27361 5
Activation of nmda receptors and postsynaptic events 0.4427674195229171 0.7179332398371807 0.4727984513536565 1.0 1.0 24 P54646,Q13509 2
Formation of xylulose 5 phosphate 0.8680864589955477 0.7170934772290996 0.4733164202349496 1.0 1.0 2 P14550 1
Signaling by ptk6 0.4250426114928141 0.7144767631684769 0.4749324198055502 1.0 1.0 11 P11802,P40763,Q07666 3
Rna polymerase i transcription termination 0.4238911376978305 0.7086457571576665 0.4785443336314845 1.0 1.0 11 O15160,P19447,P17480,P52434,P62875 5
Extracellular matrix organization 0.4362959633311949 0.7082180238179928 0.4788098750246776 1.0 1.0 23 P17655,P35613,Q15149,Q9Y296,Q32P28 5
Flt3 signaling in disease 0.524894311408199 0.7000909494116325 0.4838705076311771 1.0 1.0 5 P62993,Q06124 2
Cdc6 association with the orc origin complex 0.8623649078194537 0.6992838549815583 0.4843746547249687 1.0 1.0 2 Q9UBD5 1
Recycling pathway of l1 0.4339901771505567 0.6960537516782961 0.4863951681780611 1.0 1.0 23 Q13509 1
Regulation of pten gene transcription 0.4138780996207264 0.6896184291317071 0.4904341748546141 1.0 1.0 19 Q14839,O94776,Q9Y2Q5,Q13330,P28482,O60341,Q13547,Q16576,Q9BTC8 9
Gastrin creb signalling pathway via pkc and mapk 0.5212859517313032 0.6856376176119743 0.4929416538095028 1.0 1.0 5 P62993 1
Diseases of programmed cell death 0.4224959977015126 0.6848009797149344 0.4934695170548382 1.0 1.0 21 Q14181,P02545,P49642,Q13546,P17655,P04179,Q07021,Q16576,P26358 9
Processive synthesis on the lagging strand 0.4074788068174006 0.6751447186484394 0.4995838247032922 1.0 1.0 12 Q14181,P49642,P18858,P28340,P12004,Q9Y2S7 6
Cell cell junction organization 0.4348089162855347 0.6722141940675758 0.5014473460439695 1.0 1.0 9 O60716,P55196,P14923,P35222 4
Metabolism of porphyrins 0.4334987546260707 0.665985120766209 0.5054206109556787 1.0 1.0 9 P22830 1
Deactivation of the beta catenin transactivating complex 0.4334135908035544 0.6655806794842117 0.5056791590614695 1.0 1.0 9 P35222,Q13547 2
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.4877481927292433 0.6643643711564262 0.5064571306249195 1.0 1.0 6 P28482,Q13547 2
Prevention of phagosomal lysosomal fusion 0.6406826162220565 0.6550834141782463 0.5124140500785894 1.0 1.0 3 O14964 1
Myoclonic epilepsy of lafora 0.8455181182453915 0.6476182971487674 0.5172318599913392 1.0 1.0 2 P13807 1
Termination of translesion dna synthesis 0.3960686944616772 0.6462658603411809 0.5181071934097357 1.0 1.0 17 Q9NR33,P35249,P35250,P28340,Q9NRF9,P12004,Q14258,P40937,P35251,Q14694,Q9Y2S7,Q07864 12
Trna modification in the mitochondrion 0.4824350191085223 0.6424176696182816 0.5206020299875762 1.0 1.0 6 Q969Y2,Q9Y606 2
Hats acetylate histones 0.4046156808675097 0.6406346672988734 0.5217600704228342 1.0 1.0 19 Q96L91,Q6IA86,P51610,Q16576,Q12962,Q9Y6J9 6
Metabolism of water soluble vitamins and cofactors 0.478677966772302 0.6360058739914938 0.5247725934533765 1.0 1.0 36 P34896,Q9NRN7,P00374,Q13085,Q13057,Q4G0N4,P05165,P11498,P35030,Q96RQ3 10
G0 and early g1 0.508134140483127 0.633605531475157 0.5263382900055427 1.0 1.0 5 P06493,Q13547 2
Energy dependent regulation of mtor by lkb1 ampk 0.4348588143330908 0.6335234150165205 0.5263918951554207 1.0 1.0 8 P54646 1
Class i peroxisomal membrane protein import 0.3988530766856551 0.6312057361459283 0.5279060118557708 1.0 1.0 12 P40855,Q9Y5Y5,P33897,Q9NR77,O75381 5
Peroxisomal lipid metabolism 0.3770586192026307 0.6234324332044014 0.5330003903028673 1.0 1.0 14 Q15067,O15254,P09110 3
Golgi cisternae pericentriolar stack reorganization 0.4059163037394581 0.6191305791533844 0.5358303399624678 1.0 1.0 11 O95067,P28482,P14635 3
Selective autophagy 0.4550865527391893 0.6014231431577223 0.5475581880128462 1.0 1.0 32 O60664,P67870,Q13509,P19784,O43237,Q8N4H5,P54646,Q9BVA1 8
Bbsome mediated cargo targeting to cilium 0.4493290220446174 0.5985385730623447 0.5494806291143781 1.0 1.0 7 P78371,P48643,P49368,Q9NQ48 4
Inactivation of csf3 g csf signaling 0.4709965253979125 0.5958483477581566 0.5512765418581949 1.0 1.0 6 Q15369,P40763,P07948 3
Nephrin family interactions 0.4259076294780131 0.5927717178750047 0.5533339376181576 1.0 1.0 8 O43707,Q13813,P12814,P35609,Q9Y5K6 5
Prolonged erk activation events 0.4473807819516074 0.5902377676497857 0.555031254979619 1.0 1.0 7 P31946,P28482,Q02750 3
Signaling by notch3 0.4668761448352164 0.579318212148198 0.5623744790577201 1.0 1.0 6 Q15398,Q9Y6A5 2
Gap filling dna repair synthesis and ligation in gg ner 0.3875848276870259 0.577216755558395 0.5637930395249184 1.0 1.0 18 Q9NR33,P35249,P35250,P18858,P28340,Q9NRF9,P12004,P49916,P40937,P35251,Q9Y2S7,Q07864 12
Erk mapk targets 0.40528616562551 0.5734642359670168 0.5663304077631828 1.0 1.0 10 P51452 1
Rmts methylate histone arginines 0.391010788627264 0.5706403806370064 0.5682434400954928 1.0 1.0 19 Q9BQA1,Q96GM5,P51532,Q99873,P11802,Q16576 6
Visual phototransduction 0.4191746709444882 0.5625896764767674 0.5737143233694422 1.0 1.0 8 P09455,P53582 2
Regulation of ifng signaling 0.6111287758346527 0.5574992295488067 0.5771863853335368 1.0 1.0 3 P42224,Q06124 2
Regulation of ifna signaling 0.6111287758346527 0.5574992295488067 0.5771863853335368 1.0 1.0 3 P42224,Q06124 2
Signaling by fgfr2 0.4041946559215688 0.5446073090785334 0.586023626717946 1.0 1.0 23 P52597,Q06124,P24928,P31943,P52434,P62875,P28482,P62993,O15514,Q01085 10
Signaling by fgfr 0.4041946559215688 0.5446073090785334 0.586023626717946 1.0 1.0 23 P52597,Q06124,P24928,P31943,P52434,P62875,P28482,P62993,O15514,Q01085 10
Repression of wnt target genes 0.5105580837288333 0.5378086652357216 0.5907091490524352 1.0 1.0 4 Q13363,Q13547 2
Signaling by notch1 pest domain mutants in cancer 0.4546995012509167 0.5313038344256261 0.5952082486998689 1.0 1.0 6 Q13547 1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3864342188856146 0.524766299267006 0.5997456618300034 1.0 1.0 20 Q9NR33,P35249,P35250,P28340,P12004,Q9NRF9,Q14258,P35251,Q92890,Q14694,Q9Y2S7,P40937,Q07864 13
Pyrimidine salvage 0.5980153746306947 0.5158553860944268 0.6059554157749254 1.0 1.0 3 Q9BZX2 1
Met activates ptpn11 0.5951360772680598 0.5068642433677512 0.612250075939075 1.0 1.0 3 P62993 1
Notch1 intracellular domain regulates transcription 0.4481357014884938 0.5059808612724005 0.6128700852859326 1.0 1.0 6 Q13547 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3860791969533614 0.5009119606732877 0.6164330844553123 1.0 1.0 21 Q9NR33,P35249,P35250,P18858,P28340,P12004,Q9NRF9,Q86W56,P09874,P35251,P40937,Q9Y2S7,Q07864,P40938 14
Traf3 dependent irf activation pathway 0.7911633820724684 0.4902936955873777 0.6239260875273274 1.0 1.0 2 Q7Z434 1
Traf6 mediated irf7 activation 0.7911633820724684 0.4902936955873777 0.6239260875273274 1.0 1.0 2 Q7Z434 1
Pcna dependent long patch base excision repair 0.3692648739004133 0.4864959374753376 0.6266155850011386 1.0 1.0 18 Q9NR33,P35249,P35250,P18858,P28340,Q9NRF9,P12004,P40937,P35251,Q9Y2S7,Q07864,P40938 12
Amyloid fiber formation 0.4425328533308681 0.4846998937059054 0.6278892419078921 1.0 1.0 6 Q9UJY5 1
Defective intrinsic pathway for apoptosis 0.3769679859195152 0.4823923317774478 0.6295272674531844 1.0 1.0 11 P04179,P02545,Q07021,P17655 4
Tnf signaling 0.4672122077489838 0.4796982632638562 0.6314419630167782 1.0 1.0 5 O95429 1
Map3k8 tpl2 dependent mapk1 3 activation 0.5863034109574184 0.479645976176852 0.6314791483871454 1.0 1.0 3 Q13616 1
Regulation of tnfr1 signaling 0.7867132867132764 0.4781507080582769 0.632542942956976 1.0 1.0 2 Q13546 1
Neurexins and neuroligins 0.3837481627421655 0.4755045257896615 0.6344274081844665 1.0 1.0 10 Q14168,Q15334,Q9Y2J2,Q9Y2H0,Q9HCM4,O43491 6
Formation of apoptosome 0.5847167721249482 0.4748165348405829 0.6349177464789224 1.0 1.0 3 P28482 1
Cytochrome c mediated apoptotic response 0.5847167721249482 0.4748165348405829 0.6349177464789224 1.0 1.0 3 P28482 1
Purinergic signaling in leishmaniasis infection 0.5842984731689621 0.4735464195391048 0.6358233915925513 1.0 1.0 3 P09601 1
Inflammasomes 0.5842984731689621 0.4735464195391048 0.6358233915925513 1.0 1.0 3 P09601 1
The nlrp3 inflammasome 0.5842984731689621 0.4735464195391048 0.6358233915925513 1.0 1.0 3 P09601 1
Pyruvate metabolism and citric acid tca cycle 0.4438261939621827 0.4735379408443351 0.6358294390871384 1.0 1.0 36 Q8NCN5,P53597,Q9H9P8,P36957,P23368,Q15120,P08559,P35613,Q99643,Q6P587,P48735 11
Lagging strand synthesis 0.3665119089681339 0.4733524423197238 0.6359617534198208 1.0 1.0 18 Q14181,P35249,P35250,P49642,P18858,P28340,P12004,P40937,P35251,Q9Y2S7,P40938 11
Chromatin modifying enzymes 0.5208270116510333 0.471633248223893 0.6371885905753825 1.0 1.0 58 Q9H7B4,Q96L91,Q9BTC8,Q9BQA1,Q96GM5,Q8NB78,O00422,O15047,P11802,Q03164,Q12962,Q9Y6J9,Q9UPP1 13
Inla mediated entry of listeria monocytogenes into host cells 0.7838525111252339 0.4704103876060846 0.6380618441561081 1.0 1.0 2 P35222 1
Signal transduction by l1 0.3817281722988773 0.4666258942798864 0.6407675574488112 1.0 1.0 10 P67870,Q02750,P19784,P05556,P36507,P28482 6
Role of lat2 ntal lab on calcium mobilization 0.7822631913540921 0.4661328318149927 0.6411204238978261 1.0 1.0 2 P62993 1
Regulation of kit signaling 0.7822631913540921 0.4661328318149927 0.6411204238978261 1.0 1.0 2 P62993 1
Mrna decay by 5 to 3 exoribonuclease 0.3960786114423348 0.4626410037327179 0.6436217125228014 1.0 1.0 8 Q96F86,P26196,Q9Y4Z0 3
Cytosolic trna aminoacylation 0.3866122446639771 0.4613514116535601 0.6445465051952826 1.0 1.0 23 P41252 1
Rna polymerase ii transcription 0.2153910382885719 0.4613480404460235 0.6445489234784709 1.0 1.0 289 P28070,P31751,Q03164,P35250,P00390,O96017,Q9P0S2,Q92620,Q99873,Q9C0J8,P54646,Q16576,Q14997,Q13472,Q9UQ84,Q96P16,Q99436,Q8N684,P49721,P30260,Q8TBX8,Q7LG56,Q9Y6N1,Q6PD62,P31946,P20618,Q92804,P11802,Q9HCE1,O14497,Q9Y255,Q14353,P25786,O15047,P46937,Q5VT52,Q07955,O15514,O14548,P29083,P49841,Q8IYB3,Q08170,Q92696,Q9H1A4,Q00534,Q12996,Q06124,Q15369,P04179,P09874,P00403,P19447,Q8N7H5,Q12962,P67870,Q9UJX5,P19784,O94776,P35998,P62875,Q9BXP5,Q96GM5,Q6UN15,P24928,Q9UIV1,Q9Y2Q5,Q9BXW9,Q93009,O14744,Q14839,Q10570,Q05519,P51532,P42224,Q13526,Q9NVC6,Q9C0C2,P62304,Q9GZS3,Q13547,Q13616,P35222,P11413,P14635,P52434,P28482,Q9NVM9 88
Senescence associated secretory phenotype sasp 0.3634794141763436 0.4590356590855975 0.6462085591245041 1.0 1.0 18 Q00534,P40763,P11802,P28482,P30260,Q9H1A4 6
Signaling by mras complex mutants 0.7794024157660524 0.4584744565777368 0.646611609821252 1.0 1.0 2 P31946 1
Hdr through single strand annealing ssa 0.3484264088818544 0.4541437418470322 0.6497253717694251 1.0 1.0 15 Q13472 1
Homologous dna pairing and strand exchange 0.3484264088818544 0.4541437418470322 0.6497253717694251 1.0 1.0 15 Q13472 1
Phosphorylation of the apc c 0.3698688079448778 0.4505941547021623 0.6522820802888538 1.0 1.0 11 Q9UJX5,P53350,P14635,P30260,Q9H1A4 5
Apoptotic factor mediated response 0.4582967555201394 0.4481231172789411 0.6540643451052712 1.0 1.0 5 Q07021 1
Regulation of tp53 expression and degradation 0.3761218277935951 0.442291285333936 0.6582784363308898 1.0 1.0 10 Q93009,O96017 2
Tbc rabgaps 0.3442666385924372 0.4345396571176628 0.6638966034534715 1.0 1.0 15 Q9Y3P9,Q9UJY5,Q15907 3
Maturation of sars cov 1 nucleoprotein 0.7698664971392184 0.4333382924880532 0.6647690230201344 1.0 1.0 2 P49840 1
Meiotic recombination 0.373956888542025 0.433019292473858 0.6650007541688778 1.0 1.0 10 Q13472 1
Signaling by fgfr2 in disease 0.3564431095331056 0.4288422428741192 0.6680380346972976 1.0 1.0 12 P62993,O15514,P24928 3
Downregulation of tgf beta receptor signaling 0.4271399774300409 0.4279580832202411 0.6686816382410066 1.0 1.0 6 Q9Y5K5 1
Rhou gtpase cycle 0.3470422717553247 0.4257254020496475 0.6703079499940463 1.0 1.0 16 Q92783,P62993 2
Non integrin membrane ecm interactions 0.4489848776392839 0.4160246346788781 0.677391976935859 1.0 1.0 5 P11047,P05556,Q9Y296 3
Pecam1 interactions 0.7622377622377625 0.4136774133288611 0.6791103706984705 1.0 1.0 2 P07948 1
Pi 3k cascade fgfr4 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr1 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Downstream signaling of activated fgfr1 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr3 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Frs mediated fgfr2 signaling 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Downstream signaling of activated fgfr3 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Frs mediated fgfr3 signaling 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Pi 3k cascade fgfr2 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Frs mediated fgfr1 signaling 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Downstream signaling of activated fgfr2 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Stat5 activation 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Tie2 signaling 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Downstream signaling of activated fgfr4 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Frs mediated fgfr4 signaling 0.7622377622377523 0.4136774133288347 0.6791103706984898 1.0 1.0 2 P62993 1
Signaling by leptin 0.762237762237749 0.4136774133288256 0.6791103706984964 1.0 1.0 2 P40763 1
Recognition of dna damage by pcna containing replication complex 0.3483022671321913 0.410399122619155 0.6815131897910109 1.0 1.0 17 Q9NR33,P35249,P35250,P28340,Q9NRF9,P12004,Q16531,P40937,P35251,Q9Y2S7,Q07864 11
Intrinsic pathway for apoptosis 0.3426533806689091 0.4057185636403494 0.6849494008207895 1.0 1.0 16 P28482,Q07021,P31751,P40763 4
Suppression of phagosomal maturation 0.4206007754252844 0.4046800181119382 0.6857127319039378 1.0 1.0 6 P52294,O14964 2
Insulin receptor signalling cascade 0.4205332605289479 0.4044424076701173 0.685887420736482 1.0 1.0 6 P28482,P31751,P62993 3
Signaling by flt3 fusion proteins 0.4701319543411713 0.4007389063496543 0.6886123629584593 1.0 1.0 4 P62993 1
Perk regulates gene expression 0.332104499714973 0.4001369460586168 0.689055653253823 1.0 1.0 14 O95453,Q06265,Q9NQT5,Q96B26 4
Receptor mediated mitophagy 0.5588010326864601 0.3987271158160147 0.6900942857141923 1.0 1.0 3 P67870 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3578152441075523 0.3984593102585483 0.6902916461253379 1.0 1.0 11 O43684,O60566,Q9H1A4,P30260 4
Apc cdc20 mediated degradation of nek2a 0.3578152441075523 0.3984593102585483 0.6902916461253379 1.0 1.0 11 O43684,O60566,Q9H1A4,P30260 4
Transport and synthesis of paps 0.7561983471074307 0.3984052067852158 0.6903315204610141 1.0 1.0 2 O43252 1
Met receptor recycling 0.4186400876840473 0.3978028112527995 0.6907755448512041 1.0 1.0 6 P62993 1
Telomere c strand synthesis initiation 0.4430047914964057 0.3959157716267332 0.6921671656907458 1.0 1.0 5 Q14181 1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3722659164977945 0.3944570523462486 0.693243629338183 1.0 1.0 9 Q14168,P07196,P35609,Q13555,P28482,P27361 6
Fgfr2 alternative splicing 0.3491039912486079 0.3936290933962425 0.6938548984013311 1.0 1.0 18 P24928,P31943,P52434,P62875,P52597,O15514,Q01085 7
Pp2a mediated dephosphorylation of key metabolic factors 0.5567567567567456 0.3929629687284223 0.694346832415347 1.0 1.0 3 P30154,Q14738 2
Constitutive signaling by aberrant pi3k in cancer 0.4416052736903171 0.3912690726430901 0.6955983567935831 1.0 1.0 5 P62993,O43815 2
Metabolism of vitamins and cofactors 0.4623310734915385 0.3820330409510643 0.7024368569168742 1.0 1.0 47 P34896,O75874,P00374,Q13085,Q5HYK3,P09455,P05165,P11498,P35030,Q96RQ3 10
Trna modification in the nucleus and cytosol 0.326987403339681 0.3771890785059091 0.7060330960172361 1.0 1.0 14 Q9Y606,Q5VV42,O75648,Q96FX7,Q9NXH9,Q7Z4G4,Q9NPF4 7
Dna damage bypass 0.3607650106799816 0.3673475037498543 0.713359824263305 1.0 1.0 22 Q9NR33,P35249,P35250,P28340,P12004,Q16531,Q9NRF9,Q14258,P35251,Q92890,Q14694,Q9Y2S7,P40937,Q07864 14
Signaling by met 0.3515400452539154 0.3655248086243196 0.7147196914568452 1.0 1.0 20 Q96S59,P62993,P40763,Q92783 4
Prolactin receptor signaling 0.5443734528681801 0.3588488355222712 0.7197081769915137 1.0 1.0 3 Q13616 1
Cytosolic sensors of pathogen associated dna 0.345310092386108 0.358017096770485 0.7203305190767859 1.0 1.0 19 Q13546,O15160,P19474,P35222 4
Gab1 signalosome 0.5436297905912837 0.3568451929509824 0.7212077015072944 1.0 1.0 3 P62993 1
Negative regulation of mapk pathway 0.3383648173120258 0.3515689977095618 0.7251615188950873 1.0 1.0 12 Q02750,P31946,P28482,P30086 4
Sars cov 2 infection 0.364930660472773 0.3490734629295757 0.7270341584914386 1.0 1.0 24 P78362,Q13724,P61803,P17844,Q99873,P49840,Q96SB4 7
Hdr through homologous recombination hrr 0.3645000230957508 0.3473423373049243 0.7283341477656058 1.0 1.0 24 Q13472,Q9NRF9 2
Interleukin 21 signaling 0.7298156389065324 0.334899173624259 0.7377011454963069 1.0 1.0 2 P40763 1
Interleukin 9 signaling 0.7298156389065324 0.334899173624259 0.7377011454963069 1.0 1.0 2 P40763 1
Notch3 intracellular domain regulates transcription 0.5349037910229578 0.3337302367758091 0.7385831307827979 1.0 1.0 3 Q15398 1
Negative epigenetic regulation of rrna expression 0.3564557033907367 0.332315363712606 0.7396511399238523 1.0 1.0 23 O15160,O00422,P17480,P26358,Q13547 5
Abc transporters in lipid homeostasis 0.4459292810885204 0.3266493376562164 0.7439331226038883 1.0 1.0 4 P33897 1
Potential therapeutics for sars 0.403520550164225 0.325861804517974 0.74452891526682 1.0 1.0 35 Q99720,O00422,Q9BTC8 3
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.3473651317774268 0.325469497190325 0.744825764719002 1.0 1.0 10 Q7L5D6,P09601 2
Resolution of abasic sites ap sites 0.3659701551690732 0.3201400753393773 0.74886214727434 1.0 1.0 26 Q9NR33,P35249,P35250,P18858,P28340,P12004,Q9NRF9,Q86W56,P09874,P29372,P35251,P49916,P40937,Q9Y2S7,Q07864 15
Negative regulation of the pi3k akt network 0.3189576875370662 0.3070511040344759 0.758804474340564 1.0 1.0 13 Q8TBX8,P31751,O43815,P28482,P62993 5
Pi3k akt signaling in cancer 0.333850802932274 0.3027384151597256 0.7620892196437505 1.0 1.0 11 P31751,O43815,P49841,P49840,P62993 5
Recruitment of numa to mitotic centrosomes 0.4019567839952269 0.2932050846224898 0.769365397835698 1.0 1.0 37 O95684,P06493,P43034,O43805,Q9BSJ2,Q13509,P07437,Q7Z460,P53350,Q9NVX0,Q13561,P23258,Q9BVA1,Q14203,Q15691,Q15154 16
Downregulation of smad2 3 smad4 transcriptional activity 0.4331522601396053 0.2903717754811248 0.7715318338634605 1.0 1.0 4 Q13547 1
Cell cell communication 0.3568776070001673 0.2864652062726611 0.7745218386849984 1.0 1.0 26 Q9BY67,O43707,P55196,Q13418,O60716,P35222,Q06124,P21333,Q13813,P12814,P35609,Q15149,Q9Y5K6,P05556,P14923,P62993 16
Interferon alpha beta signaling 0.3503883736068534 0.2862194841562794 0.7747100215102365 1.0 1.0 8 P55265,Q06124,Q9Y3Z3 3
Nuclear events stimulated by alk signaling in cancer 0.3200899956349572 0.2804151255197719 0.7791590338838372 1.0 1.0 12 Q86WB0,Q9HC35,P40763,P28482,Q13616 5
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.7047043865225575 0.2796633093799217 0.7797358303406818 1.0 1.0 2 Q13547 1
Methylation 0.3821825465830223 0.2795141385213551 0.7798502892708308 1.0 1.0 6 P31153,Q99707,Q9NZL9 3
Postmitotic nuclear pore complex npc reformation 0.3417904188474879 0.2770090089755279 0.7817731885772976 1.0 1.0 23 Q8NFH3,Q8WYP5 2
Metabolism of ingested semet sec mesec into h2se 0.7024793388429738 0.2750283499772825 0.7832944577330723 1.0 1.0 2 P23526 1
Folding of actin by cct tric 0.343807986868328 0.263698531289521 0.7920122273505787 1.0 1.0 8 P78371,P48643,P50990,P40227,Q99832,P49368 6
Rab regulation of trafficking 0.3836606563737282 0.2571562655812032 0.7970581439097644 1.0 1.0 35 P51151,Q9Y3P9,P86790,P31751,P62330,Q13636,Q9UJY5,Q15907,Q9Y296 9
Rna polymerase i transcription 0.339564589658375 0.2546981610663728 0.7989562366732677 1.0 1.0 24 Q14839,O15160,P19388,O94776,P19447,P17480,P52434,P62875,Q16576,Q13547,Q9BTC8 11
Signaling by notch1 0.3403888608971184 0.2523232546833384 0.8007912148836547 1.0 1.0 8 Q13547 1
Polymerase switching on the c strand of the telomere 0.2957572899913759 0.2511901576845555 0.8016670937030996 1.0 1.0 14 Q14181,P35249,P35250,P49642,P28340,P12004,P40937,P35251,Q9Y2S7 9
Diseases of mitotic cell cycle 0.3039817062949019 0.2510467118294246 0.8017779944978003 1.0 1.0 13 P11802,Q00534,Q9H1A4,P30260 4
Complex i biogenesis 0.366356824410409 0.2506254329316738 0.8021037165288463 1.0 1.0 31 O43676,P28331,O96000,Q9P0J0,Q9BQ95 5
Regulation of signaling by cbl 0.4163982909218414 0.2460586311216456 0.8056368462570347 1.0 1.0 4 P62993 1
Dual incision in gg ner 0.322621379571926 0.2396110769314451 0.8106317767555198 1.0 1.0 21 Q9NR33,P35250,Q9NRF9,Q16531,P09874,P19447,Q9Y2S7 7
Pi5p regulates tp53 acetylation 0.4950266686105633 0.2380685401183946 0.8118279346542308 1.0 1.0 3 Q13526 1
Rna polymerase iii transcription initiation from type 1 promoter 0.3135345975128068 0.2311613441437494 0.8171894596373628 1.0 1.0 11 Q8WUA4,O15160,Q12789,P52434,P62875 5
Syndecan interactions 0.4101642531357102 0.2305623322227895 0.8176548337094975 1.0 1.0 4 P05556,Q9Y296 2
Rna polymerase iii transcription initiation from type 3 promoter 0.3491282983325577 0.2299281434495713 0.8181476068251166 1.0 1.0 7 P62875,O15160,P52434 3
Rna polymerase iii chain elongation 0.3491282983325577 0.2299281434495713 0.8181476068251166 1.0 1.0 7 P62875,O15160,P52434 3
Notch hlh transcription pathway 0.4909646269115964 0.2293041063533033 0.8186325620977581 1.0 1.0 3 Q13547 1
Ecm proteoglycans 0.6783216783216758 0.227542275762868 0.8200020999165503 1.0 1.0 2 P11047 1
Laminin interactions 0.6783216783216758 0.227542275762868 0.8200020999165503 1.0 1.0 2 P11047 1
Platelet adhesion to exposed collagen 0.6783216783216721 0.2275422757628611 0.8200020999165556 1.0 1.0 2 P07948 1
Rab gefs exchange gtp for gdp on rabs 0.3383414257112305 0.2242546645310388 0.8225591502796652 1.0 1.0 26 P51151,P86790,P31751,Q13636,Q9Y296 5
Cellular response to hypoxia 0.3875189838766628 0.2240970781534207 0.8226817659672749 1.0 1.0 39 P20618,P28070,Q9Y241,Q15369,Q99436,P49721,Q14997 7
Trna aminoacylation 0.3648449856529432 0.222169747943138 0.8241817432674872 1.0 1.0 33 O43324,Q5ST30,Q9BW92,P41252,Q15046,Q15031 6
Apc c cdc20 mediated degradation of cyclin b 0.3166384876956126 0.2183275556828947 0.827173905954339 1.0 1.0 10 Q9UJX5,Q9H1A4,P30260,P14635 4
P75ntr negatively regulates cell cycle via sc1 0.672917991099796 0.2176460945258084 0.8277048670510037 1.0 1.0 2 Q13547 1
Activation of anterior hox genes in hindbrain development during early embryogenesis 0.2898201320586581 0.2156032514057957 0.8292970211538695 1.0 1.0 15 P24928,P52434,P62875,Q16576,O15514 5
Formation of the beta catenin tcf transactivating complex 0.3155243719510356 0.2148339141535581 0.829896810520216 1.0 1.0 10 P51532,Q13547 2
Rrna processing in the mitochondrion 0.3800644503109779 0.2126950322374654 0.8315648418120145 1.0 1.0 5 Q8WVM0 1
E3 ubiquitin ligases ubiquitinate target proteins 0.2886376687588523 0.2117410031291343 0.8323090974315617 1.0 1.0 15 P50542,Q9GZS3,O75381,Q6PD62,Q8N7H5,P78527 6
Uch proteinases 0.3896093181642027 0.2007449098680357 0.8408980414475717 1.0 1.0 42 P20618,P28070,P51610,Q8NB78,Q99436,Q16186,Q9Y5K5,P49721,Q14997 9
Assembly of the orc complex at the origin of replication 0.3385821890873928 0.2002897759995394 0.8412539581170011 1.0 1.0 7 O60684,Q9Y619,Q9UBD5 3
Transcriptional regulation by ventx 0.3027911788727352 0.1972789066628538 0.8436092850211001 1.0 1.0 11 P35222,Q9H1A4,P30260,Q9HCE1 4
Regulation of plk1 activity at g2 m transition 0.370185147270912 0.1957314483455367 0.8448203682610576 1.0 1.0 37 O95067,O95684,P06493,P43034,Q13616,O43805,P62140,O14974,P07437,Q7Z460,P53350,Q9NVX0,P14635,Q13561,P23258,Q14203,Q15691,Q15154 18
Mtor signalling 0.286513913518559 0.191649750622016 0.8480165694163586 1.0 1.0 16 Q9Y376,P54646,P31751 3
Vegfr2 mediated vascular permeability 0.3008335477399867 0.1914158494028347 0.8481998036178904 1.0 1.0 11 P14923,P31751,P35222 3
Glyoxylate metabolism and glycine degradation 0.2857441624721389 0.1909870980983786 0.8485357013279047 1.0 1.0 13 P08559,Q9NR77 2
Infectious disease 0.1960201278386096 0.1894572283435564 0.8497344747932711 1.0 1.0 334 Q99720,P12235,P37198,P62841,P28070,Q9Y6W5,P20618,P62910,Q02750,Q13724,P61978,Q8NFH3,P61927,P61254,O94776,Q9BRG1,Q92804,P35998,P36507,P61313,P62266,O43865,Q9UQB8,O60716,Q13509,P07948,O43237,P24928,P25786,P42677,P17844,Q99873,P83881,P49840,P62993,O15514,Q13547,Q16576,Q14997,P53680,O00159,Q02543,P35222,Q99436,P29083,P60866,P46776,P49841,P52434,P28482,Q92783,P49721,Q9BVA1,Q96SB4,Q9BTC8,P23246,Q9NRG9,O14964,P61160,P78362,Q99567,P84098,Q9Y2Z0,Q13546,Q10567,O00422,Q15369,P09874,P09601,P61803,P19447,Q9UN37,Q9Y3U8,Q12962 74
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.2920354915546324 0.1869655885336162 0.8516876135212414 1.0 1.0 12 Q14839,O94776,Q13330,Q16576,Q13547,Q9BTC8 6
Mrna capping 0.2762099362964871 0.1862206491461972 0.8522717315023902 1.0 1.0 14 P24928,P19447,P52434,P62875,O15514 5
Metabolism of rna 0.1343575587916176 0.1859625440663502 0.8524741344279678 1.0 1.0 458 P28070,P26196,P61978,Q9BUJ2,Q92917,P62266,Q8WUA2,Q92620,Q96F86,Q9BQ52,Q9C0J8,Q14997,P35637,Q9BQA1,Q02543,Q96FX7,Q99436,Q8N684,P49721,Q9NWZ8,Q9BUQ8,Q9Y3U8,P04792,P31946,O75494,P20618,P62910,Q15637,P61927,P62995,P08579,P55795,O43660,Q9NQT5,P25786,P42677,Q13151,P17844,Q9NXH9,P83881,Q07955,O15514,P55265,O43290,O43390,Q96B26,P14866,P46776,Q8IYB3,Q08170,Q6P2E9,Q5RKV6,Q9HCS7,Q9NRX1,P78346,Q12996,P19447,Q9H0D6,Q96BP3,Q8WVM0,P61254,Q8NFH3,P35998,P62875,Q06265,P61313,Q15477,Q8TEQ6,Q53GS7,Q9Y4Z0,Q9BXP5,Q6UN15,P24928,Q9UIV1,Q9UQ35,Q5SY16,Q2NL82,Q969Y2,O14744,O95453,P51991,P18621,P57678,Q10570,P78406,Q05519,Q68CQ4,Q6P2Q9,Q86XP3,O15213,Q99567,Q15007,P52597,P37198,P62841,Q9C0C2,P62304,P31943,Q9UHX1,Q9GZS3,P60866,P52434,Q9GZL7,Q9NRG9,Q9Y606,P84098,O75648,Q92945 108
Sting mediated induction of host immune responses 0.3472727404637398 0.185894421707728 0.8525275567901898 1.0 1.0 6 P19474 1
The phototransduction cascade 0.3656418235364577 0.1790941561303619 0.8578637705560594 1.0 1.0 5 P53582 1
Copi independent golgi to er retrograde traffic 0.3300851884670272 0.1779411410466578 0.8587692005122727 1.0 1.0 28 Q13509,Q9BVA1 2
Signaling by braf and raf1 fusions 0.3064852315206979 0.1778217129924758 0.8588629946051913 1.0 1.0 22 P02545,O43252,Q02750,P28482,Q7Z2W4,P30086,P31946 7
Regulation of tp53 activity 0.3934255598701968 0.1767696679573946 0.859689315279017 1.0 1.0 46 P67870,P35250,Q13472,O96017,Q9UQ84,P31751,P19784,Q92804,Q13526,Q12962,P54646,Q93009,Q16576,Q13547 14
Interconversion of nucleotide di and triphosphates 0.2892190030077253 0.1751157680429579 0.8609886686066852 1.0 1.0 18 P35754,Q7LG56,P15531,P23921,P04818 5
Integration of energy metabolism 0.2970489511578026 0.1740953441461087 0.8617905321599255 1.0 1.0 20 P54646 1
Rna polymerase iii transcription 0.2866000596089009 0.1712643099069806 0.8640159423694329 1.0 1.0 12 Q8WUA4,O15160,Q12789,P52434,P62875 5
Post translational protein modification 0.1591742111048158 0.1681074792423924 0.8664987255042569 1.0 1.0 385 O94979,P37198,P20618,P28070,Q9NZL9,O14579,Q8NB78,Q13724,O95394,Q8NFH3,P61962,P61978,Q13636,Q16186,Q86UV5,Q14258,Q92564,Q06210,P26358,Q14165,P61923,Q13509,Q8NEZ5,Q9GZS3,O43237,Q7Z434,O75381,P48444,Q5JRA6,Q12888,Q96SB8,Q93009,Q13547,Q13616,Q16576,Q14997,P50542,P51151,Q9HA64,P51610,P61026,Q9BW61,Q96FW1,Q13438,Q99436,Q9Y5K5,Q15907,Q9Y296,Q9NYU2,Q92783,P49721,Q9BVA1,Q86YN1,Q14203,Q96GG9,Q9NRG9,O14964,Q8WVM7,Q02818,P35606,Q99567,Q13546,P45974,Q15369,O94888,P61803,Q14166,Q96MF7,Q8N6T3,Q8N7H5,Q9NWV8,Q96E22,Q6PD62,Q9Y678,Q12962,Q07065 76
Translocation of slc2a4 glut4 to the plasma membrane 0.3521281229997952 0.1679829897176669 0.866596661153237 1.0 1.0 35 P54646,Q13509,O00161,Q9BVA1 4
Recruitment of mitotic centrosome proteins and complexes 0.3411370952877849 0.1677736500954149 0.8667613528135678 1.0 1.0 32 O95684,P06493,P43034,O43805,Q9BSJ2,P07437,Q7Z460,P53350,Q9NVX0,Q13561,P23258,Q14203,Q15691,Q15154 14
Cellular responses to stimuli 0.1834203208481808 0.166397223410098 0.8678443588930371 1.0 1.0 323 O94979,P37198,P67870,Q9Y241,P62841,P28070,P20618,P62910,P19784,Q8NFH3,P61927,P11802,Q06265,Q06210,P61313,Q9HCE1,P62266,Q96L91,P02545,P48723,P00390,Q9P0S2,Q9NQT5,Q13509,O43237,Q8TCT9,P25786,P42677,P83881,P49840,Q16576,O14548,O95453,Q13616,Q14997,P31689,P53004,Q02543,P40763,Q96B26,Q99436,O95429,P60866,P46776,P49841,P28482,P49721,Q9BVA1,P30260,Q14203,P21281,Q9NRG9,Q5RKV6,Q00534,Q99567,P84098,Q99543,Q9Y3U8,Q99757,Q9Y6N1,Q15369,P00403,P09601,Q8N6T3,P04792,Q92945,P49748 67
Signaling by ntrk2 trkb 0.4575741516039935 0.1646045504889087 0.8692552493057415 1.0 1.0 3 P62993 1
Fgfr2 mutant receptor activation 0.2886136558966053 0.1570430643901054 0.8752109086804436 1.0 1.0 11 O15514,P24928 2
Signaling by fgfr2 iiia tm 0.2886136558966053 0.1570430643901054 0.8752109086804436 1.0 1.0 11 O15514,P24928 2
Irs mediated signalling 0.3740602118417572 0.1520662219186498 0.8791347053341259 1.0 1.0 4 P31751,P62993 2
Rna polymerase iii transcription termination 0.3062433925862405 0.1519442338042282 0.8792309197759498 1.0 1.0 8 P62875,O15160,P52434 3
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.3061884867614555 0.1518031853083639 0.8793421697411525 1.0 1.0 8 Q93009 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3297943766909162 0.1495476864373047 0.8811214840565997 1.0 1.0 31 Q13509,Q9BVA1 2
Dual incision in tc ner 0.3404045974261246 0.1490207659343863 0.8815372470767167 1.0 1.0 34 Q9HCS7,Q9NR33,P35250,P19388,Q9NRF9,Q16531,P24928,P19447,Q9Y2S7,P52434,P62875,Q93009,O15514 13
Transcription of the hiv genome 0.3107144427659364 0.1486279513788747 0.8818472159636714 1.0 1.0 26 Q15369,Q92804,Q12962,O15514 4
Anchoring of the basal body to the plasma membrane 0.3329322290344103 0.1483981877287515 0.8820285302205655 1.0 1.0 32 O95684,P06493,P43034,O43805,Q15019,P07437,Q7Z460,P53350,Q9NVX0,Q13561,P23258,Q14203,Q15691,Q15154 14
Tgf beta receptor signaling activates smads 0.3038263546589146 0.1457992512417032 0.8840798670104872 1.0 1.0 8 P62136,Q9Y5K5,P61081,P62140 4
Activation of gene expression by srebf srebp 0.277888992308861 0.1451483191454241 0.8845937690429473 1.0 1.0 18 Q13085 1
Ripk1 mediated regulated necrosis 0.2837659285379998 0.1444855524965925 0.8851170641811434 1.0 1.0 11 Q13546 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.3865757606324183 0.1415141887019028 0.8874637518776882 1.0 1.0 49 O95067,P20618,P28070,Q14997,Q13509,P53350,Q99436,P14635,P49721,Q9BVA1,Q15691 11
Mitotic telophase cytokinesis 0.2744461141888991 0.1391059249704903 0.8893664463005582 1.0 1.0 12 Q02241,Q8WVM7 2
Alk mutants bind tkis 0.3251640759886453 0.1378160622151334 0.8903857896832088 1.0 1.0 6 O43815 1
Aurka activation by tpx2 0.3213392741574947 0.131182864578198 0.8956306508952698 1.0 1.0 31 O95684,P06493,P43034,O43805,P07437,Q7Z460,P53350,Q9NVX0,Q13561,P23258,Q14203,Q15691,Q15154 13
Cell cycle mitotic 0.2604394468218576 0.1308286150447018 0.8959108860115945 1.0 1.0 254 P37198,P20618,P28070,P67870,Q9BSJ2,P00374,P42166,P31751,P19784,Q8NFH3,P53350,P11802,Q96EA4,Q8WYP5,Q15003,Q15691,Q99640,Q9UPP1,Q14181,Q9UBD5,P02545,P35250,Q13509,Q9NRF9,P07948,O43237,P25786,P42677,Q9Y619,P62140,Q2NKX8,Q13547,Q14997,Q86Y07,O95067,Q13616,Q96IY1,Q15154,Q9NR33,P49642,O14974,P49736,Q99436,Q9HBM1,P04818,P49841,P14635,P28482,P49721,Q9BVA1,Q14203,P30260,Q9H1A4,O95684,O75122,Q8IXJ6,P43034,Q00534,Q02241,O43264,Q99567,Q9NRG9,O43684,O60566,Q7Z460,Q9UN37,Q8WVM7,O43805 68
Neurotransmitter receptors and postsynaptic signal transmission 0.3231277360467944 0.127549267484958 0.8985056817587567 1.0 1.0 32 P54646,Q13509 2
Developmental biology 0.2128385515698362 0.1274527597321472 0.8985820604493142 1.0 1.0 250 Q96P70,P20618,P28070,P67870,P62841,Q9NVC6,P62910,P31751,Q02750,P19784,P61254,P61927,P35998,P36507,P11802,P62875,Q03164,P15924,P61313,P62266,P46939,Q8N8S7,Q13509,P07948,P24928,P25786,P42677,P46937,P83881,Q14126,Q16576,O15514,Q14997,P62993,O15144,Q96S59,P04632,P53680,Q9NR77,Q02543,P40763,P35222,P51532,Q99436,P46776,P49841,P60866,P52434,P14923,O00560,P49721,Q9BVA1,P28482,O75122,P61160,P84098,Q06124,Q15369,Q7Z460,Q9Y3U8 60
Signaling by rho gtpases miro gtpases and rhobtb3 0.2069416089418965 0.1255733497456714 0.9000696597554412 1.0 1.0 246 O60664,Q9Y6W5,P42166,Q16513,Q8NFH3,P53350,Q08378,Q96EA4,Q9NSV4,P15924,Q15691,Q8WYP5,Q9NSK0,Q9UEY8,P62995,Q9UQB8,Q13576,Q13509,Q8NHP6,O43237,P42677,Q8N392,P62140,Q14126,Q2NKX8,P62993,Q07021,O75323,O15173,Q96IY1,P51151,Q9UNZ2,P35222,Q9HBM1,Q8N684,P14923,Q92783,Q9BVA1,P28482,Q12792,Q9Y2I1,Q9NRG9,O75122,O14964,P43034,P61160,Q9NYL9,O43264,P52306,O43684,Q99707,O60566,Q9P2R3,Q7Z460,Q9H2G2,Q9P0I2,O00161,Q13526,Q68EM7,Q5JTV8,P31946,Q07065 62
Regulation of hmox1 expression and activity 0.3577821245326666 0.1228362805030794 0.9022367441137892 1.0 1.0 43 P20618,P67870,P28070,Q13616,P19784,Q8TCT9,P09601,Q99436,P49721,Q14997 10
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3356027523155351 0.1202264316366061 0.9043037802160804 1.0 1.0 5 P31751,P62993 2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.2589540031724029 0.1196749098585476 0.9047406765216204 1.0 1.0 16 Q07065,Q02818,O43852,Q5JRA6 4
Apoptotic execution phase 0.3039225020146765 0.1180623079915851 0.9060182883912472 1.0 1.0 28 Q9P289,P35222,Q15149,Q14126,P15924 5
Interleukin 4 and interleukin 13 signaling 0.2651830970663497 0.1173595023418972 0.9065751746933324 1.0 1.0 12 P09601,P40763 2
Regulation of pten stability and activity 0.3406034543917401 0.1154245145860988 0.9081086489886848 1.0 1.0 39 P20618,P67870,P28070,P31751,P19784,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 21
Rac3 gtpase cycle 0.3231073192912554 0.114246039754822 0.909042756355498 1.0 1.0 34 O15173,Q9UQB8,O00161,Q68EM7,Q14126 5
Translation 0.1411327212933741 0.1110417816028491 0.9115832146544468 1.0 1.0 215 P62841,O43324,Q9BYD1,P61927,P41252,Q9NP92,Q9Y291,P61313,P62266,P55010,Q9Y3B7,Q5ST30,Q9BW92,Q9NVS2,Q13144,Q15046,P13798,Q16540,Q9NYK5,Q13405,Q13084,P60866,P84098,Q13347,Q15031 25
Hiv elongation arrest and recovery 0.2615317738121109 0.1086320975854437 0.9134943012098437 1.0 1.0 18 O15514,Q15369,P24928 3
Nervous system development 0.1571715193525144 0.1082321010197148 0.9138115815833804 1.0 1.0 209 Q96P70,P20618,P28070,Q92769,P67870,P62841,P62910,Q92747,Q02750,P19784,P61254,Q13813,P61927,P35998,P36507,Q13153,P61313,Q02878,P62701,P62266,P46939,O94813,Q8N8S7,Q13509,P35580,P07948,P25786,P42677,P39023,P46937,P50914,P46783,P83881,P62993,Q14997,O15144,Q96S59,P53680,P18621,Q9NR77,Q02543,O75832,P25398,P51532,Q99436,P46776,P49841,P60866,Q9BPU6,O00560,P49721,Q9BVA1,P28482,O75122,P61160,P84098,O94887,Q06124,Q15369,Q7Z460,P11047,O15145,O95372,P05556,Q9Y3U8,P62753 66
Protein ubiquitination 0.2754836839163572 0.1061130968080349 0.9154926200650564 1.0 1.0 22 P50542,P78527,P45974,Q9GZS3,O75381,Q8N7H5,Q6PD62,Q93009 8
Rhobtb2 gtpase cycle 0.263908169588571 0.1057354531351122 0.9157922504761882 1.0 1.0 19 P78371,Q9NYL9,P62995,Q16643,Q9UM54,O43396,Q8IYB3,Q12792 8
Molybdenum cofactor biosynthesis 0.5934520025429055 0.103612216935196 0.9174770921375172 1.0 1.0 2 Q9NQX3 1
M phase 0.2334154404380985 0.102147367722151 0.918639703609758 1.0 1.0 196 P37198,P20618,P28070,P67870,Q9BSJ2,P42166,P19784,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q15003,Q15691,Q9UPP1,P02545,Q13509,O43237,P25786,P42677,Q2NKX8,Q14997,Q15154,O95067,Q96IY1,Q99436,Q9HBM1,P14635,P28482,P49721,Q9BVA1,Q14203,P30260,Q02241,O95684,O75122,Q8IXJ6,P43034,Q9NRG9,O43264,Q99567,O43684,O60566,Q7Z460,Q9UN37,Q8WVM7,O43805 46
Rna polymerase i promoter escape 0.2425996045426444 0.1021016367317729 0.9186760018816844 1.0 1.0 14 O15160,P19447,P17480,P52434,P62875 5
Prc2 methylates histones and dna 0.3242474475730936 0.1019193019339441 0.9188207290140468 1.0 1.0 5 P26358 1
Mitochondrial iron sulfur cluster biogenesis 0.3432917092216849 0.1008472641816328 0.9196717066705395 1.0 1.0 4 P22570 1
Metabolism of amino acids and derivatives 0.1855381710868209 0.1002759027420173 0.9201252878777888 1.0 1.0 192 P20618,P28070,P62841,O43324,P62910,P36957,Q96H78,P61927,P41252,P61313,P62266,P34896,P00390,O43252,Q14353,P25786,P42677,Q9Y619,Q15046,P83881,Q96RQ3,Q14997,Q9NR77,Q02543,P09417,Q99436,P46776,P60866,P49721,Q9BV57,P84098,Q99757,Q99707,P08559,Q9Y3U8 35
Abortive elongation of hiv 1 transcript in the absence of tat 0.2407964212076449 0.0985779904652806 0.9214733459521354 1.0 1.0 14 O15514,P24928 2
Metabolism of steroids 0.3542178290406378 0.0976998440476206 0.922170639397692 1.0 1.0 47 Q15125,Q15800,Q15392,Q13085,O95772 5
Processing of capped intron containing pre mrna 0.2223737956417834 0.0974693748226255 0.9223536537552868 1.0 1.0 186 P37198,O75494,Q96BP3,Q15637,P61978,Q8NFH3,P62304,P31943,Q9BUJ2,Q92917,P62875,Q9UHX1,Q53GS7,P62995,Q8WUA2,P08579,P55795,O43660,Q9Y4Z0,Q9BXP5,Q6UN15,P24928,Q92620,Q13151,P17844,Q9UQ35,Q9C0J8,Q07955,O15514,P35637,P51991,O43290,Q10570,O43390,P78406,Q05519,P14866,Q8IYB3,Q08170,Q6P2Q9,Q8N684,P52434,Q86XP3,Q9HCS7,Q9NRG9,Q99567,Q12996,P19388,Q9BUQ8,P84103,Q15007,P52597,Q8NFH5 53
Oncogenic mapk signaling 0.2791406948840949 0.0932305442452386 0.9257204092590888 1.0 1.0 25 P02545,O43252,Q02750,P28482,Q7Z2W4,P62140,P30086,P31946 8
Adaptive immune system 0.202331932223858 0.0923260471483655 0.9264389941168996 1.0 1.0 175 O94874,O94979,P20618,P28070,Q6P179,P31751,P55786,P19474,Q9NZ08,Q9NSK0,O43865,Q13509,Q8NEZ5,P07948,O43237,P25786,Q5T447,P62993,Q14997,Q13616,P53680,Q13867,Q99436,P52732,P49721,Q9BVA1,Q14203,P30260,Q9H1A4,Q02241,Q7KYR7,Q10567,Q15369,O94822,O00161,Q03518,P31946 37
Cdt1 association with the cdc6 orc origin complex 0.3185041273109978 0.0909139483419239 0.9275609669185252 1.0 1.0 37 P20618,P28070,P25788,P43686,P35998,Q9UBD5,P62333,P25786,Q9Y619,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 20
Dissolution of fibrin clot 0.4043118418542338 0.0891167178735268 0.9289891513154682 1.0 1.0 3 P35237 1
Pten regulation 0.3821121245249365 0.0886314775510208 0.9293747910539034 1.0 1.0 60 P20618,P67870,P28070,Q92769,P31751,P19784,P25788,P43686,O94776,P35998,Q13330,O60341,Q9HCE1,P62333,Q86YP4,P25786,Q6IAA8,Q9Y2Q5,Q93009,Q99460,O00231,O00487,Q14997,Q16576,P27361,Q13547,Q14839,O75832,Q15022,Q99436,O00232,P25789,P28482,P49721,Q9BTC8,P49720,P48556,Q8WXI9 38
Cytokine signaling in immune system 0.1713175267934298 0.0876524178312686 0.9301529390618744 1.0 1.0 165 O60573,P37198,P20618,P28070,Q07820,P31751,Q02750,Q8NFH3,Q14258,P19474,P07948,P25786,P29372,P62993,Q14997,Q13616,P55265,Q9Y3Z3,Q53EL6,P40763,O14979,P51532,Q99436,P28482,Q13126,P49721,P07355,Q99439,Q9NRG9,Q99567,P52597,Q06124,Q15369,P09601,Q13526,P51452 36
Resolution of sister chromatid cohesion 0.3896704831548769 0.0865249603808923 0.9310491149590734 1.0 1.0 64 Q8NFH3,P53350,Q96EA4,Q8WYP5,Q15691,Q13509,O43237,P42677,O95067,Q96IY1,Q9HBM1,P14635,Q9BVA1,O75122,P43034,O43264,O43684,O60566,Q7Z460,Q8WVM7 20
Mitotic g1 phase and g1 s transition 0.4082580081981102 0.0858210297627121 0.9316086888202704 1.0 1.0 73 P20618,P28070,P00374,P31751,P11802,Q9UBD5,Q14181,P07948,Q9NRF9,Q9Y619,Q13547,Q13616,Q9NR33,P49642,P49736,Q99436,P04818,P14635,P49721,Q00534 20
Rhod gtpase cycle 0.280235154844649 0.0840626603960288 0.9330066122126786 1.0 1.0 27 O15173,Q9UEY8,P42166,Q8NHP6,Q9P2R3,Q68EM7,Q5JTV8,Q9NSV4 8
Telomere c strand lagging strand synthesis 0.2513596311246031 0.0837302907015024 0.9332708732046112 1.0 1.0 19 Q14181,P35249,P35250,P49642,P18858,P28340,P12004,P35251,P40937,Q9Y2S7,P40938 11
Signaling by tgfb family members 0.2431717964924298 0.0825212029650741 0.934232258306788 1.0 1.0 17 Q7Z3T8,Q9Y5K5,P62140,P28482,Q13547 5
L1cam interactions 0.3276254427857295 0.0825075643043477 0.934243103400616 1.0 1.0 42 Q96P70,Q96S59,P67870,P53680,Q02750,Q13509,P19784,Q13813,P11047,O95372,P05556,P36507,P28482,O00560,Q9BVA1 15
Transcriptional regulation by runx2 0.3504330993144057 0.0823364983991026 0.9343791314137646 1.0 1.0 50 P20618,P28070,P31751,P25788,P43686,P35998,P11802,P62333,P06493,P25786,P46937,P27361,Q99460,O00487,Q13616,O00231,Q14997,O75832,Q99436,O00232,P42224,P14635,P49841,P25789,P28482,P49721,P49720,P48556,Q96PK6 29
Abc transporter disorders 0.3272541194809293 0.0820602720437737 0.93459878485002 1.0 1.0 42 P20618,P28070,P33897,Q13438,Q99436,O75477,P49721,Q14997 8
Degradation of cysteine and homocysteine 0.2906458423960357 0.0807179906635596 0.9356662290214124 1.0 1.0 6 Q99757,P25325 2
Mrna splicing 0.2624248699578785 0.0773773311208644 0.9383233738517976 1.0 1.0 143 O75494,Q96BP3,Q15637,P61978,P62304,P31943,Q9BUJ2,Q92917,P62875,Q9UHX1,P62995,Q8WUA2,P08579,P55795,O43660,Q9Y4Z0,Q9BXP5,Q6UN15,P24928,Q92620,Q13151,P17844,Q9UQ35,Q9C0J8,Q07955,O15514,P35637,P51991,O43290,Q10570,O43390,Q05519,P14866,Q8IYB3,Q08170,Q6P2Q9,Q8N684,P52434,Q86XP3,Q9HCS7,Q12996,P19388,Q9BUQ8,P84103,P52597 45
Synthesis of diphthamide eef2 0.3923688394276646 0.0767232727556657 0.938843690125852 1.0 1.0 3 Q9BQC3,P13639 2
Mitotic metaphase and anaphase 0.2593286603414254 0.0755099787084559 0.9398089583438032 1.0 1.0 139 P37198,P20618,P28070,P42166,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q15691,P02545,Q13509,O43237,P25786,P42677,Q2NKX8,Q14997,Q86Y07,O95067,Q96IY1,Q99436,Q9HBM1,P14635,P49721,Q9BVA1,P30260,Q9H1A4,O75122,Q8IXJ6,P43034,O43264,O43684,O60566,Q7Z460,Q9UN37,Q8WVM7 35
Diseases of signal transduction by growth factor receptors and second messengers 0.2460978782146601 0.0750429809203844 0.9401805144523968 1.0 1.0 138 O94979,P20618,P28070,P31751,Q02750,Q7Z2W4,P35998,P36507,P62875,P02545,Q86WB0,O43252,Q6UN15,P07948,P24928,P25786,P62140,P30086,P49840,P62993,O15514,Q14997,Q13616,Q13547,P31939,P40763,O43815,P35222,Q13438,Q99436,O95429,P49841,P52434,P28482,P49721,Q14203,Q8IWJ2,O95684,Q06124,P31946,Q16630 41
Cell cycle checkpoints 0.278358683680168 0.0736444536213787 0.9412932982770856 1.0 1.0 135 P20618,P28070,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q99640,Q15691,Q9UBD5,P35250,O96017,O43237,P25786,P42677,Q9Y619,Q12888,Q14997,O95067,Q96IY1,Q13472,Q9UQ84,P49736,Q99436,Q9HBM1,P14635,P49721,P30260,O75122,P43034,O43264,O43684,O60566,Q7Z460,Q9NWV8,P31946 35
Trafficking of ampa receptors 0.2697452229299364 0.0732990426530169 0.9415681535047716 1.0 1.0 8 P53680,Q96CW1,P63010,Q15334,Q9UM54,Q13555,P46459 7
Ret signaling 0.3885401860837831 0.0730795710014624 0.9417427981624618 1.0 1.0 3 P62993 1
Sars cov infections 0.3624254924984195 0.0719568731166029 0.9426362291044912 1.0 1.0 59 Q99720,P78362,Q13546,O00422,Q13724,Q9BTC8 6
Met activates ptk2 signaling 0.3868945312692763 0.0715613593152073 0.942950991998563 1.0 1.0 3 P11047 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.2761595320005491 0.0704639201494644 0.9438244166920612 1.0 1.0 7 P14635,Q99873 2
Influenza infection 0.0945519513187656 0.0703758215587688 0.943894535124479 1.0 1.0 128 P37198,P62841,P62910,P61254,Q8NFH3,P61927,P62487,P62875,P61313,Q02878,P62701,P62266,O00505,P24928,P39023,P42677,P50914,P46783,P83881,O15514,P18621,Q02543,P78406,P25398,P52294,P46776,P60866,P52434,Q9NRG9,Q99567,P84098,P19388,P09874,Q9Y3U8,Q8NFH5,P62753 36
Regulation of expression of slits and robos 0.0969087263801239 0.0685094307325428 0.9453801130771242 1.0 1.0 124 P20618,P28070,P62841,P62910,P32969,P61254,P61927,P43686,P35998,P46779,P61313,Q02878,P62701,P62888,P62266,P62333,O94813,P25786,P42677,P39023,P50914,P46783,P46778,P83881,Q99460,Q14997,P18621,Q02543,O75832,P25398,O00232,Q99436,P05388,P46776,P60866,P25789,P18077,P49721,P18124,Q07020,P48556,P84098,Q15369,Q9Y3U8,P62753 45
Transcriptional regulation by runx1 0.3659575220424378 0.067926994327044 0.9458437500107936 1.0 1.0 63 P20618,P67870,P28070,P19784,Q03164,Q9HCE1,O14497,Q96GM5,P25786,O15047,P46937,Q99873,Q13547,Q14997,P51532,Q99436,P49721,Q00534,Q06124 19
Stabilization of p53 0.298425099758737 0.0668719737706933 0.9466836247715432 1.0 1.0 37 P20618,P28070,P25788,P43686,P35998,P62333,O96017,P25786,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 19
Transcriptional regulation by tp53 0.2743500976925921 0.0666473467224945 0.9468624522766336 1.0 1.0 120 P67870,P31751,Q9C0C2,P19784,Q92804,P35250,P00390,O96017,Q9P0S2,Q9Y255,P24928,Q9BXW9,Q99873,P54646,Q93009,Q16576,O15514,O14548,Q13547,Q13472,Q9UQ84,P11413,P14635,P52434,Q13526,Q8TBX8,Q7LG56,Q15369,P00403,Q9Y6N1,Q12962 31
Cyclin a cdk2 associated events at s phase entry 0.3064305904860332 0.0660939905595072 0.947302995230425 1.0 1.0 40 P20618,P28070,P31751,P25788,P43686,P35998,P11802,P62333,P25786,Q99460,O00231,Q13616,O00487,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 20
Signaling by receptor tyrosine kinases 0.2124444549465704 0.0657103121008143 0.9476084622902964 1.0 1.0 118 Q96P70,Q9Y6W5,P31751,Q02750,P62330,P31943,P36507,P62875,Q01085,O43865,O60716,Q9UQB8,P07948,P24928,P46937,P62993,O15514,Q13547,Q14839,Q96S59,P53680,Q13685,P40763,P38606,P35222,P42224,P52434,P14923,P28482,Q92783,P21281,O14964,Q9Y6I3,P19388,P52597,Q06124,P04792,P51452,Q13043,P31946 40
Autophagy 0.3314978739355297 0.0644694433715391 0.9485964371371816 1.0 1.0 50 O60664,P67870,Q13509,P19784,O43237,Q8N4H5,Q7Z3C6,P54646,Q9Y4P1,Q9BVA1 10
Fceri mediated mapk activation 0.2643018317884057 0.0641526166752752 0.9488487060451792 1.0 1.0 8 P28482,P62993 2
Rho gtpase effectors 0.2451269845386173 0.063845213402668 0.9490934765826696 1.0 1.0 114 Q9Y6W5,Q16513,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q9NSV4,Q9NSK0,Q15691,Q9UQB8,Q13576,Q13509,O43237,P42677,P62140,Q2NKX8,P62993,Q96IY1,P35222,Q9HBM1,P28482,Q9BVA1,O75122,P43034,P61160,O43264,O43684,O60566,Q7Z460,Q13526,P31946 31
Rho gtpases activate formins 0.355242907828536 0.0634892308030082 0.9493769345182576 1.0 1.0 61 O75122,Q96IY1,P43034,O43264,O43684,Q13509,O60566,O43237,Q8NFH3,P53350,Q8WYP5,P42677,Q9HBM1,Q9BVA1,Q7Z460,Q96EA4,Q9NSV4,Q15691 18
Formation of the early elongation complex 0.2252469019229111 0.0622570916454785 0.9503580980624666 1.0 1.0 16 P24928,P19447,P52434,P62875,O15514 5
Asymmetric localization of pcp proteins 0.2902455390897157 0.0618975638701574 0.950644407529914 1.0 1.0 36 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556,Q14160 19
Defective cftr causes cystic fibrosis 0.3043696395346945 0.0617290663270469 0.9507785925201366 1.0 1.0 41 P20618,P28070,Q13438,Q99436,O75477,P49721,Q14997 7
G1 s dna damage checkpoints 0.2955173387014807 0.0614035053120326 0.9510378607943472 1.0 1.0 38 P20618,P28070,P25788,P43686,P35998,P62333,O96017,P25786,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 19
Epigenetic regulation of gene expression 0.3033865764956181 0.0609072320670896 0.9514330897848312 1.0 1.0 41 Q14839,O15160,P52434,Q9BTC8,O00159,P19388,O00422,O94776,P19447,Q13330,P17480,P49841,P62875,Q16576,P26358,Q13547 16
Dna repair 0.2127259530213168 0.0605799414481322 0.9516937485843197 1.0 1.0 107 Q9NR33,Q13472,O96017,Q9UQ84,Q8N3C0,Q6P6C2,P16455,Q9NRF9,P24928,P29372,Q9BXW9,Q12888,Q93009,O15514 14
Separation of sister chromatids 0.3177770064226582 0.0598382534101209 0.9522844583329058 1.0 1.0 105 P20618,P28070,Q9UJX5,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q15691,Q13509,O43237,P25786,P42677,Q2NKX8,Q14997,Q96IY1,Q99436,Q9HBM1,P49721,Q9BVA1,P30260,Q9H1A4,O75122,P43034,O43264,Q14674,O43684,O60566,Q7Z460,Q8WVM7 29
Orc1 removal from chromatin 0.3165324369054042 0.0588833910584024 0.953044987110738 1.0 1.0 47 P20618,P28070,P25788,P43686,P35998,Q9UBD5,P25205,P62333,P25786,Q9Y619,Q99460,O00231,O00487,Q13616,Q14997,P33993,O75832,P49736,Q99436,O00232,P25789,P49721,P49720,P48556 24
Mitotic prometaphase 0.3689872726032868 0.0584611086423463 0.9533813402931584 1.0 1.0 95 P67870,Q9BSJ2,P19784,Q8NFH3,P53350,Q96EA4,Q8WYP5,Q15003,Q15691,Q13509,O43237,Q15154,O95067,Q96IY1,Q9HBM1,P14635,Q9BVA1,Q14203,O95684,O75122,O43264,O43684,O60566,Q7Z460,Q8WVM7,O43805 26
Class i mhc mediated antigen processing presentation 0.2476524341659494 0.0582515835584792 0.953548232707318 1.0 1.0 102 O94874,O94979,P28070,Q6P179,P55786,P19474,Q9NZ08,Q8NEZ5,Q5T447,Q13616,Q14997,Q13867,Q99436,P49721,P30260,Q15369,O94822,O00161,Q03518 19
The citric acid tca cycle and respiratory electron transport 0.2593575162618655 0.0577904517978311 0.953915543830604 1.0 1.0 101 O43676,Q9H9P8,Q9P0S2,P51970,P28331,P00403,P35613,O96000,Q9P0J0,Q9BQ95,O14548,P48735 12
Signaling by interleukins 0.1635199621276379 0.0577821135945497 0.9539221856556324 1.0 1.0 101 P20618,P28070,Q07820,Q02750,P07948,P25786,P62993,Q13616,Q14997,Q53EL6,P40763,O14979,P51532,Q99436,P28482,Q13126,P49721,P07355,Q99439,P51452,Q06124,P09601,P52597 23
Regulation of ras by gaps 0.2852627775637699 0.0575628460835717 0.9540968451066072 1.0 1.0 36 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,O75832,P62195,Q99436,O00232,P25789,P49721,P49720,P48556 19
Degradation of dvl 0.2852627775637699 0.0575628460835717 0.9540968451066072 1.0 1.0 36 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,O75832,P62195,Q99436,O00232,P25789,P49721,P49720,P48556 19
Cross presentation of soluble exogenous antigens endosomes 0.2821080152616491 0.0573394824927379 0.954274769592377 1.0 1.0 35 O00487,P62333,P20618,P28070,P48556,O75832,P25788,P43686,P25786,Q99436,O00232,P35998,P25789,P49721,Q99460,O00231,Q14997,P49720 18
Degradation of axin 0.2821080152616491 0.0573394824927379 0.954274769592377 1.0 1.0 35 O00487,P62333,P20618,P28070,P48556,O75832,P25788,P43686,P25786,Q99436,O00232,P35998,P25789,P49721,Q99460,O00231,Q14997,P49720 18
Tnfr2 non canonical nf kb pathway 0.2926280300864795 0.0567173939613076 0.9547703179417756 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P61081,P62333,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,Q8TBC4,P49720,P48556 21
Dectin 1 mediated noncanonical nf kb signaling 0.2926280300864794 0.0567173939613074 0.9547703179417756 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P61081,P62333,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,Q8TBC4,P49720,P48556 21
Scf skp2 mediated degradation of p27 p21 0.292521993048814 0.0566360120629418 0.95483514709465 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P11802,P62333,P25786,Q99460,O00231,Q13616,O00487,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 19
Programmed cell death 0.2214740763558948 0.0549857629673035 0.9561498061391036 1.0 1.0 95 P20618,P28070,P31751,Q15149,P15924,P02545,Q9P289,Q07021,Q14126,Q14997,P40763,P35222,O00273,Q99436,P28482,O00560,P49721,Q13546,P31946 19
Diseases of mismatch repair mmr 0.3653677067907652 0.0542396197540013 0.956744255128307 1.0 1.0 3 P52701 1
Regulation of runx2 expression and activity 0.294520813617097 0.0541978863548587 0.956777504655844 1.0 1.0 41 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P42224,P49841,P25789,P49721,P49720,P48556 21
Formation of rna pol ii elongation complex 0.257467359208684 0.0541715729697417 0.9567984689016158 1.0 1.0 28 Q15369,Q9GZS3,P24928,Q8N7H5,O15514 5
S phase 0.227198955749057 0.0540544370106589 0.956891793137933 1.0 1.0 93 P20618,P28070,Q9UJX5,P31751,P35998,P11802,Q9UBD5,Q14181,P35250,Q9NRF9,P25786,Q9Y619,Q9Y2S7,Q14997,Q13616,Q9NR33,P49642,P49736,Q99436,P49841,P49721,P30260,Q9H1A4,Q8WVM7 24
Organelle biogenesis and maintenance 0.2006764887242877 0.0540526858488033 0.956893188323234 1.0 1.0 93 O95684,Q13509,P54646,Q9BVA1,P48735 5
Mitotic spindle checkpoint 0.3251330534004043 0.0533133873210745 0.9574822138321448 1.0 1.0 55 O75122,Q2NKX8,Q96IY1,P43034,O43264,O43684,O60566,O43237,Q8NFH3,P53350,P42677,Q9HBM1,Q7Z460,Q96EA4,Q8WYP5,Q9H1A4,Q15691,P30260 18
Selenoamino acid metabolism 0.1929435924169091 0.0531203306512807 0.9576360328035258 1.0 1.0 91 P62841,O43324,P62910,P61254,P61927,P23526,P41252,P61313,Q02878,P62701,P62266,P00390,O43252,P32929,P39023,P42677,P50914,Q15046,P46783,P46778,P83881,P18621,Q02543,P07814,Q12904,P57772,P25398,P46776,P60866,P84098,Q9Y3U8,P47897,P62753 33
Srp dependent cotranslational protein targeting to membrane 0.0851060819298392 0.0531202071724879 0.9576361311864436 1.0 1.0 91 P62841,P62910,P39656,P32969,P61254,P61927,P43307,P46779,P61313,Q02878,P62701,P62266,O76094,P39023,P42677,P50914,P46783,P46778,P83881,P18621,Q9Y5M8,Q02543,P25398,P61009,P46776,P60866,Q07020,Q9UHB9,P84098,Q9Y3U8,P62753 31
Mitotic g2 g2 m phases 0.3350005252450065 0.0529494756840927 0.9577721637612944 1.0 1.0 87 P20618,P28070,Q9BSJ2,P53350,Q99640,Q15691,Q13509,P25786,P62140,Q14997,Q13616,O95067,Q15154,Q99436,P14635,P49721,Q9BVA1,Q14203,O95684,P43034,Q7Z460,O43805 22
Dna replication 0.1986607176281376 0.0512561675672815 0.9591213953776808 1.0 1.0 87 P20618,P28070,Q9UJX5,P35998,Q9UBD5,O60684,Q14181,P35250,Q9NRF9,P25786,Q9Y619,Q9Y2S7,Q14997,Q13616,Q9NR33,P33993,P49642,P49736,Q99436,P49721,P30260,Q9H1A4 22
Mapk family signaling cascades 0.2337323367150394 0.0507975588349271 0.9594868361351572 1.0 1.0 86 P36404,P07196,P20618,P28070,Q96P70,Q02750,P35998,P36507,Q9HCE1,P25786,P62140,P30086,P62993,Q14997,Q14168,Q96S59,Q99436,P28482,P49721,Q06124,P04792,P31946 22
Slc transporter disorders 0.2731207848433222 0.0505013428107975 0.9597228793636106 1.0 1.0 35 P37198,Q99567,Q8NFH3,P35613,O00400 5
Deubiquitination 0.2511786193639889 0.0498903105859935 0.9602097987216824 1.0 1.0 84 P20618,P28070,Q9NZL9,Q8NB78,Q14258,Q16186,Q86UV5,Q7Z434,Q93009,Q14997,P51610,Q96FW1,Q99436,Q9Y5K5,Q92783,P49721,O14964,Q13546,P45974,Q9NWV8,Q12962 21
Apoptosis 0.2657002768635793 0.049479762034495 0.9605369649989672 1.0 1.0 83 P20618,P28070,P02545,Q9P289,Q13546,P49721,P31751,P40763,P35222,O00273,Q99436,Q15149,Q07021,P28482,Q14126,P31946,P15924,Q14997 18
Cytoprotection by hmox1 0.3281891291575124 0.0492673800518305 0.9607062148834236 1.0 1.0 64 P20618,P67870,P28070,Q13616,Q9P0S2,P40763,P19784,Q8TCT9,P25786,P00403,Q99436,P09601,Q9Y6N1,P49721,O14548,Q14997 16
Hedgehog off state 0.3067055797327295 0.0492418244230682 0.960726580606282 1.0 1.0 50 P20618,P28070,Q13616,Q13509,P25786,Q99436,P49841,P49721,Q9BVA1,Q14997 10
Synthesis of dna 0.2086054003888174 0.0489274587766962 0.9609771061232666 1.0 1.0 82 P20618,P28070,Q9UJX5,P35998,Q9UBD5,Q14181,P35250,Q9NRF9,P25786,Q9Y619,Q9Y2S7,Q13616,Q14997,Q9NR33,P49642,P49736,Q99436,P49721,P30260,Q9H1A4 20
Translesion synthesis by polh 0.2240780913327541 0.0486984771864607 0.961159589466808 1.0 1.0 12 P35249,P35250,P12004,P40937,Q92890,P35251 6
Signaling by wnt 0.146495242643049 0.0484594595319383 0.9613500730673364 1.0 1.0 81 P20618,P28070,P53680,P67870,Q13616,P31751,P35222,P19784,O75436,P25786,P51532,Q99436,P49721,Q9HCE1,Q14997,Q13547 16
Intracellular signaling by second messengers 0.2901422326836781 0.048432284428965 0.9613717302328076 1.0 1.0 80 P20618,P28070,P67870,P31751,P19784,O94776,P35998,Q9HCE1,O43865,P25786,Q9Y2Q5,P49840,Q93009,Q16576,P62993,Q14997,Q13547,O43815,Q99436,P49841,P28482,P49721,Q9BTC8,Q8TBX8,Q06124 25
Tp53 regulates metabolic genes 0.2797150231531399 0.0480642497531287 0.9616650378234066 1.0 1.0 39 P00390,Q9P0S2,Q7LG56,P31751,P00403,P11413,Q9Y6N1,P54646,P31946,O14548 10
G2 m checkpoints 0.2515400559850712 0.0480474327607465 0.9616784403573851 1.0 1.0 80 O95067,Q13472,P35250,P28070,O96017,Q9UQ84,P49736,Q99436,Q9NWV8,Q9Y619,P14635,Q12888,Q9UBD5,P49721,P31946,Q99640,Q14997 17
Biological oxidations 0.2914737587575045 0.04802677422748 0.9616949044751671 1.0 1.0 44 O75223,Q9NZL9,Q8WUX2,Q96KP4,Q5VT66,P07099,P31153,P30837,P14550 9
Antigen processing ubiquitination proteasome degradation 0.2235595661898168 0.0480017991352551 0.9617148087590426 1.0 1.0 80 O94874,P20618,P28070,Q13616,Q9UJX5,Q8NEZ5,Q15369,O94822,Q13867,P25786,Q5T447,P55786,Q99436,P19474,P49721,P30260,Q9H1A4,Q14997 18
Auf1 hnrnp d0 binds and destabilizes mrna 0.2811743381734559 0.0475064256268583 0.9621096092100692 1.0 1.0 40 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q14103,Q99460,O00231,O00487,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556,P04792 20
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2811269586067988 0.0474803499020959 0.9621303911769168 1.0 1.0 40 P20618,P28070,P25786,Q99436,P49721,Q03164,Q14997 7
Negative regulation of notch4 signaling 0.2759658556620837 0.0473395033890451 0.96224264420848 1.0 1.0 38 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,Q13616,O00487,O75832,Q99436,O00232,Q9Y6A5,P25789,P49721,P49720,P48556 19
Disorders of transmembrane transporters 0.2698758688305724 0.0468115445507184 0.9626634279006152 1.0 1.0 77 Q9NRG9,P37198,P20618,P28070,Q99567,P33897,O00400,Q8NFH3,Q13438,Q99436,P35613,O75477,P49721,Q14997 14
Protein protein interactions at synapses 0.2107029859800811 0.0466723880085319 0.9627743375325551 1.0 1.0 16 Q13136,O95197,Q9Y2H0,Q14168 4
Cellular response to chemical stress 0.2973191997628476 0.0466629960132434 0.9627818231048366 1.0 1.0 75 P20618,P67870,P28070,P19784,P00390,Q9P0S2,Q8TCT9,P25786,Q13616,O14548,Q14997,P53004,P40763,Q99436,P49721,Q99757,P04179,P00403,P09601,Q9Y6N1 20
Regulation of runx3 expression and activity 0.2644677742359018 0.0466216213307265 0.9628147994356212 1.0 1.0 34 P62333,P20618,P28070,P48556,O75832,P25788,P43686,P25786,Q99436,O00232,P35998,P25789,P49721,Q99460,O00231,O00487,P49720 17
Regulation of cholesterol biosynthesis by srebp srebf 0.2379917799618849 0.0458547684593949 0.9634260057671532 1.0 1.0 25 Q13085 1
Interleukin 12 family signaling 0.2430928599304964 0.0453154061669169 0.9638559077075148 1.0 1.0 27 Q99439,Q53EL6,O14979,P40763,P04179,P52597,Q13126,P07355 8
Gp1b ix v activation signalling 0.5165289256198188 0.0452249636176952 0.9639279965142676 1.0 1.0 2 P21333 1
Apc c mediated degradation of cell cycle proteins 0.3010485498209133 0.0450677537328115 0.9640533040884468 1.0 1.0 53 P20618,P28070,Q13616,Q9UJX5,O43684,O60566,P25786,P53350,Q99436,P14635,P49721,P30260,Q9H1A4,Q14997 14
G2 m dna damage checkpoint 0.2591501934709768 0.0450071530681564 0.9641016074097348 1.0 1.0 33 Q13472,O96017 2
Golgi to er retrograde transport 0.2337092712219956 0.0443147805360717 0.9646534900847205 1.0 1.0 72 Q02241,P35606,P61923,O43264,O14579,Q13509,A2RRP1,O43237,P48444,Q8N6T3,P52732,Q9Y678,Q9BVA1,Q14203,Q9NSK0 15
Neddylation 0.2013250005112074 0.0442706930119928 0.9646886323507252 1.0 1.0 72 Q96GG9,P20618,P28070,Q13616,Q8NEZ5,Q15369,P61962,Q9BW61,O94888,Q99436,Q92564,P49721,Q16576,Q14997 14
Reduction of cytosolic ca levels 0.3494435612082676 0.0442342154137919 0.9647177087793106 1.0 1.0 3 P30626,P20020 2
Platelet calcium homeostasis 0.3494435612082676 0.0442342154137919 0.9647177087793106 1.0 1.0 3 P30626,P20020 2
Sumoylation of transcription factors 0.3491828959674868 0.0440886290372055 0.9648337566860348 1.0 1.0 3 Q12888 1
Sumoylation 0.1715970373796456 0.0433343690944369 0.9654349943695416 1.0 1.0 70 Q9NRG9,P37198,Q99567,Q8NFH3,Q96MF7,Q12888,Q8WVM7,Q96SB8,P26358,Q13547 10
Signaling by hedgehog 0.2979733923312483 0.0432109878298046 0.965533346249339 1.0 1.0 57 Q13438,P49721,Q13509 3
Sensory perception 0.2337152145591145 0.042878106791694 0.9657987009461256 1.0 1.0 25 P47756,P50579,Q9Y2J2,O00159,P53582,Q13813,P52907,P09455,Q12792,Q8TC12 10
Dna replication pre initiation 0.2947248993899417 0.0426076211049906 0.9660143202457194 1.0 1.0 60 O60684,Q14181,Q9NR33,P20618,P28070,P33993,P49642,P49736,Q9NRF9,P25786,Q9Y619,Q99436,P35998,P49721,Q9UBD5,Q14997 16
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2367136763712186 0.0425020756037176 0.9660984571547078 1.0 1.0 68 O43676,Q9P0S2,P28331,P00403,O96000,Q9P0J0,Q9BQ95,O14548 8
Ub specific processing proteases 0.2090879622933798 0.0419553692035424 0.9665342769808648 1.0 1.0 67 O14964,P20618,P28070,Q9NZL9,Q13546,P49721,P45974,Q96FW1,Q99436,Q16186,Q86UV5,Q93009,Q12962,Q14997 14
Trafficking of glur2 containing ampa receptors 0.2694877505567964 0.0419128935911644 0.9665681378314293 1.0 1.0 5 P63010,P53680,P46459,Q96CW1 4
Nef mediated cd4 down regulation 0.2694877505567956 0.0419128935911638 0.9665681378314296 1.0 1.0 5 P63010,Q9UI12,P53680,Q96CW1 4
Nef mediated cd8 down regulation 0.2694877505567956 0.0419128935911638 0.9665681378314296 1.0 1.0 5 P63010,Q9UI12,P53680,Q96CW1 4
Copi dependent golgi to er retrograde traffic 0.2862317580458894 0.0418840112909357 0.966591162354441 1.0 1.0 50 Q02241,P61923,O43264,O14579,Q13509,A2RRP1,P48444,Q8N6T3,P52732,Q9Y678,Q9BVA1,Q9NSK0 12
Positive epigenetic regulation of rrna expression 0.2426738579838283 0.0415862461676578 0.9668285377254252 1.0 1.0 29 Q14839,O15160,O00159,P19388,O94776,P49841,P52434,P62875,Q16576,Q13547,Q9BTC8 11
Extension of telomeres 0.2421630498974565 0.0412992032648279 0.9670573682325636 1.0 1.0 29 Q14181,P35249,P35250,P49642,P18858,O00743,P28340,P12004,P35251,P39748,P40937,Q9Y2S7,Q9Y265,Q9BUR4,Q9Y230,P40938 16
Aspartate and asparagine metabolism 0.2682150811326779 0.0410158579825302 0.9672832536584448 1.0 1.0 5 P00505,P08243,Q9UJS0,P17174 4
Activation of bad and translocation to mitochondria 0.2518796748501553 0.0407585111497614 0.967488415160237 1.0 1.0 7 P31751 1
Respiratory electron transport 0.2816027041964106 0.0406526797344571 0.9675727864842112 1.0 1.0 58 O43676,Q9P0S2,P28331,P00403,Q9BQ95,O96000,Q9P0J0,O14548,P51970 9
Transport of mature transcript to cytoplasm 0.1528719228678819 0.0405387907426016 0.967663581905526 1.0 1.0 64 Q53GS7,Q9NRG9,P37198,Q99567,Q10570,Q6UN15,P78406,Q9C0J8,Q8NFH3,Q05519,Q92620,P84103,Q8IYB3,Q08170,Q07955 15
Switching of origins to a post replicative state 0.2820669867274978 0.0404001152700398 0.967774138353495 1.0 1.0 55 P20618,P28070,Q13616,Q9UJX5,Q9H1A4,P49736,P25786,Q9Y619,Q99436,P35998,P49721,P30260,Q9UBD5,Q14997 14
Mrna splicing minor pathway 0.2501343429754198 0.040240319250717 0.967901533533515 1.0 1.0 33 P52434,P19388,Q9BUQ8,P24928,P55769,P62304,Q86XP3,Q6P2Q9,P62875,Q07955,Q15427,O15514,P62487 13
Cd28 co stimulation 0.2402686480528467 0.0398465458291578 0.968215467471238 1.0 1.0 9 P31751,P62993 2
Esr mediated signaling 0.2618980853896613 0.0397291864416202 0.9683090326249526 1.0 1.0 39 P52434,Q8WVM7,P31751,P24928,O15514,P17844,P04792,Q99873,P28482,Q9HCE1,Q13547 11
Nuclear envelope ne reassembly 0.2772237388490163 0.0396283414386251 0.968389431980379 1.0 1.0 51 O95067,Q8IXJ6,P37198,P02545,P42166,Q13509,Q9BVA1,Q8NFH3,P14635,Q9UN37,Q8WYP5 11
Dna double strand break repair 0.2752920368593166 0.0393439171066629 0.9686161929162248 1.0 1.0 50 Q13472,Q9NRF9,O96017 3
Interferon signaling 0.20993500799829 0.0391911305131904 0.9687380050305344 1.0 1.0 61 O60573,Q9NRG9,P37198,P55265,Q9Y3Z3,Q99567,P78406,Q06124,Q8NFH3,P52294,Q14258,P19474,P29372,P42224,Q13526,Q12899 16
Estrogen dependent gene expression 0.2381006173129719 0.0391452018591742 0.9687746226952854 1.0 1.0 29 P52434,Q8WVM7,P19388,P24928,O15514,P17844,Q99873,P62875,Q9HCE1,Q13547 10
Glucose metabolism 0.244911347795198 0.0391157747247317 0.9687980841825898 1.0 1.0 60 Q9NRG9,P37198,Q9BRR6,Q99567,P08237,Q8NFH3,A6NDG6,P11498 8
Hedgehog ligand biogenesis 0.2600217032956617 0.0390550259866357 0.9688465176535204 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,Q14997,O00487,O75832,Q13438,Q99436,O00232,P25789,P49721,P49720,P48556 19
Cilium assembly 0.2579051353763032 0.0388011425830803 0.9690489338724606 1.0 1.0 58 O95684,O43805,Q13509,Q15019,Q7Z460,P53350,Q9NQ48,Q10713,Q9BVA1,Q14203,Q15691,Q15154 12
Regulation of mrna stability by proteins that bind au rich elements 0.2093158520299821 0.0387310936563895 0.9691047828485329 1.0 1.0 60 O95453,P20618,P28070,Q9NQT5,Q96B26,P25786,Q99436,P04792,Q92945,Q06265,P49721,P31946,Q14997 13
Tcf dependent signaling in response to wnt 0.2364991785530153 0.0385316173509323 0.969263823193907 1.0 1.0 59 P20618,P67870,P28070,P31751,P35222,P19784,P25786,P51532,Q99436,P49721,Q13547,Q14997 12
Transcription coupled nucleotide excision repair tc ner 0.2672618281662968 0.0384929721685617 0.9692946347300068 1.0 1.0 45 Q9HCS7,Q9NR33,P35250,P19388,Q9NRF9,Q16531,P24928,P49916,P19447,Q9Y2S7,P52434,P62875,Q93009,O15514 14
Gene silencing by rna 0.264513653251195 0.0374980336858055 0.9700879079372364 1.0 1.0 48 Q9NRG9,P37198,Q8N2A8,Q99567,Q15631,P19388,Q9BQ52,P78406,P24928,Q8NFH3,P52434,P62875,Q8WYQ5,O15514,Q8NFH5 15
Mitochondrial translation 0.2512897870003996 0.0374621184194868 0.9701165440532832 1.0 1.0 55 Q9Y3B7,Q9BYD1,Q9NYK5,Q13405,Q9NVS2,Q9NP92,Q9Y291 7
Transcriptional regulation by runx3 0.2540609577749191 0.0371329607084248 0.970378991298296 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P62333,P25786,P46937,Q99460,O00231,O00487,O75832,P35222,Q99436,O00232,P25440,P25789,P49721,P49720,P48556 20
Signaling by notch 0.1643012674687698 0.0368155674966547 0.970632061395889 1.0 1.0 56 P20618,P28070,Q9Y6A5,P25786,Q99436,Q15398,P35998,Q9H488,P15291,P49721,Q9HCE1,Q13616,Q13547 13
Formation of tc ner pre incision complex 0.2280275726923136 0.0366757161665592 0.970743571304779 1.0 1.0 27 Q9HCS7,P19388,Q16531,P24928,P19447,Q13098,P52434,P62875,Q93009,O15514 10
Hcmv infection 0.2126257509085264 0.0364908892230687 0.9708909432194784 1.0 1.0 55 Q9NRG9,P37198,Q99567,Q13509,P61978,Q8NFH3,O43237,Q9BVA1,Q9BRG1,Q16576 10
Nuclear pore complex npc disassembly 0.2390632855418877 0.0364814629260297 0.9708984593118206 1.0 1.0 32 O95067,P37198,Q99567,Q8NFH3,P14635 5
Mhc class ii antigen presentation 0.2434654737505781 0.0364047696605548 0.9709596110629172 1.0 1.0 53 Q13509,Q9NSK0,Q9BVA1 3
Signaling by nuclear receptors 0.2314520596759201 0.0363588058148771 0.970996260642384 1.0 1.0 54 P52434,Q8WVM7,P31751,Q8NB78,P24928,Q15120,P08559,O15514,P17844,P04792,Q99873,P28482,Q9HCE1,Q13547 14
Signaling by notch4 0.2525199840150331 0.036309103085153 0.9710358915149488 1.0 1.0 40 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,Q13616,O00487,O75832,Q99436,O00232,Q9Y6A5,P25789,P49721,P49720,P48556 19
Signaling by the b cell receptor bcr 0.2538435025677161 0.0359256723094922 0.9713416255342988 1.0 1.0 43 P20618,P28070,Q13616,O43865,P07948,Q99436,P49721,P62993,Q14997 9
Nucleotide excision repair 0.2322402171348631 0.0355989889358387 0.9716021145245252 1.0 1.0 52 Q9HCS7,Q9NR33,P35250,P19388,Q9NRF9,Q16531,P24928,P09874,P49916,P19447,Q9Y2S7,P52434,P62875,Q93009,O15514 15
Glycolysis 0.2456878233525201 0.0353547276616732 0.9717968842156308 1.0 1.0 49 Q9NRG9,P37198,Q9BRR6,Q99567,P08237,Q8NFH3,A6NDG6 7
Degradation of beta catenin by the destruction complex 0.2473290121007906 0.035275342925828 0.971860184585816 1.0 1.0 48 P20618,P28070,P43686,P35998,P62333,P25786,Q99460,Q13547,Q13616,Q14997,O75832,P35222,Q14738,Q99436,O00232,P49841,P25789,P30154,P49721,P56545,P48556,Q13363 22
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.2504047695306227 0.0352595284681895 0.9718727948526896 1.0 1.0 45 P20618,P28070,Q9UJX5,P25786,P53350,Q99436,P49721,P30260,Q9H1A4,Q14997 10
Neuronal system 0.203578880048649 0.0350795301863784 0.9720163239098264 1.0 1.0 52 P54646,Q13509,Q9BVA1 3
Transmission across chemical synapses 0.2452862215579655 0.0346450512459428 0.972362777345518 1.0 1.0 40 P54646,Q13509,Q9BVA1 3
Homology directed repair 0.244263373753253 0.0346184353472108 0.972384001028977 1.0 1.0 39 Q13472,Q9NRF9 2
Base excision repair 0.2277740030672347 0.0346168783440232 0.972385242593624 1.0 1.0 29 Q9NR33,P35250,Q9NRF9,P09874,P29372,P49916,Q9Y2S7 7
Abc family proteins mediated transport 0.2002705203919697 0.0346071910010769 0.9723929673465104 1.0 1.0 51 P20618,P28070,P33897,P40855,Q13438,Q99436,O75477,P49721,Q14997 9
Fc epsilon receptor fceri signaling 0.2047551113858579 0.0342077815900908 0.9727114613624804 1.0 1.0 50 P20618,P28070,Q13616,O43865,P07948,Q99436,P28482,P49721,P62993,Q14997 10
Snrnp assembly 0.242603960369662 0.034059136044496 0.972829994277182 1.0 1.0 43 P37198,Q9BQA1,Q99567,Q8NFH3,P62304,Q9NWZ8 6
Antiviral mechanism by ifn stimulated genes 0.1416177195151918 0.0340187892289677 0.9728621677340636 1.0 1.0 50 O60573,P37198,Q99567,Q8NFH3,Q13526 5
Interleukin 1 family signaling 0.2374087292090912 0.0339686975688828 0.972902112010302 1.0 1.0 46 Q15750,P20618,P28070,Q9H0E2,Q02750,P43686,P35998,P62333,P09429,P25786,Q13616,Q14997,O75832,P40763,Q99436,O00232,P25789,P49721,P48556,Q06124 20
Hcmv early events 0.2351210257582648 0.0337902172355196 0.9730444370074968 1.0 1.0 46 P37198,Q99567,Q13509,O43237,Q8NFH3,Q9BVA1 6
C type lectin receptors clrs 0.1473281863127825 0.0335546812795681 0.9732322609990433 1.0 1.0 49 Q15750,P20618,P28070,P43686,P35998,P61081,Q13153,P62333,O43865,P07948,P25786,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,Q8TBC4,P48556 20
Signal amplification 0.2719465648855016 0.0334818220499318 0.9732903616070628 1.0 1.0 4 Q16539,Q13685,Q14344 3
Fcgr3a mediated il10 synthesis 0.2561793698754884 0.0334698250417359 0.973299928472714 1.0 1.0 5 O43865 1
Rhobtb1 gtpase cycle 0.1952095891922976 0.0333577359848013 0.9733893126888228 1.0 1.0 17 P78371,P62995,Q16643,Q9UM54,O43396,Q13098,Q8IYB3,Q8N684 8
Hiv transcription elongation 0.2083556149036058 0.0333214629825417 0.9734182382770168 1.0 1.0 22 Q15369,O15514,P24928 3
Antigen processing cross presentation 0.194541029810752 0.0332247377986338 0.9734953710992048 1.0 1.0 48 P49721,O00161 2
Mapk6 mapk4 signaling 0.1491696082983433 0.0330903384055744 0.9736025473676396 1.0 1.0 48 P20618,P28070,Q99436,P04792,P49721,Q9HCE1,Q14997 7
Factors involved in megakaryocyte development and platelet production 0.2334630481911606 0.0329903617404247 0.9736822736760916 1.0 1.0 43 Q02241,Q13509,P52732,Q9BVA1,Q13547,Q9NSK0 6
Chromosome maintenance 0.2015487532694343 0.0324442988001317 0.9741177357331368 1.0 1.0 46 Q14181,P52434,P35250,P49642,P19388,O00743,P24928,P40937,Q9Y2S7,Q92674,P62875,Q9BUR4,Q16576,O15514 14
Sumoylation of dna damage response and repair proteins 0.2290503744479117 0.0323802451626529 0.9741688163030038 1.0 1.0 42 Q9NRG9,P37198,Q99567,Q8NFH3,Q96MF7,Q96SB8 6
Pcp ce pathway 0.1149615954695655 0.0316889690687884 0.974720091878075 1.0 1.0 45 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,P53680,O75832,Q99436,O00232,P25789,P49721,P49720,P48556,Q14160 20
Clec7a dectin 1 signaling 0.2016111674639967 0.0316175864591108 0.9747770184348776 1.0 1.0 44 Q15750,P20618,P28070,P25788,P43686,P35998,P61081,P62333,O43865,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,Q8TBC4,P49720,P48556 23
Unfolded protein response upr 0.2107509158378917 0.0315085083834965 0.9748640068064588 1.0 1.0 43 O94979,P49748,P02545,Q9NQT5,P49840,Q96B26,Q8N6T3,Q92945,Q06265,Q06210,Q14203,O95453 12
Viral messenger rna synthesis 0.2262161851163792 0.0315072486390661 0.9748650114382942 1.0 1.0 37 P37198,Q99567,P24928,Q8NFH3,P52434,O15514 6
Telomere maintenance 0.2233219147724983 0.0314616098897056 0.9749014078479874 1.0 1.0 40 Q14181,P35250,P49642,P19388,O00743,P24928,Q9Y2S7,P52434,P62875,Q9BUR4,O15514 11
Interleukin 1 signaling 0.2065036121884389 0.0313574367716213 0.9749844849802 1.0 1.0 43 Q15750,P20618,P28070,Q9H0E2,Q02750,P25788,P43686,P35998,P62333,P09429,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 23
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2058337221637518 0.0312811284039057 0.9750453403948642 1.0 1.0 23 Q53EL6,P07355,O14979,P52597,Q13126,Q99439 6
Tcr signaling 0.1264061810743299 0.0312241360295032 0.9750907915283812 1.0 1.0 44 P20618,P28070,Q13616,P25786,Q99436,P35998,P49721,Q14997 8
Transcriptional regulation by small rnas 0.2193501179592892 0.0311103924505769 0.9751815017052884 1.0 1.0 40 P37198,Q99567,P24928,Q8NFH3,P52434,O15514 6
Rac2 gtpase cycle 0.2213183126907206 0.0307732957182854 0.9754503372601286 1.0 1.0 35 O15173,Q14126,Q68EM7 3
Tp53 regulates transcription of dna repair genes 0.2100777740411252 0.030627479855049 0.9755666266709192 1.0 1.0 26 Q15369,O15514,P24928 3
Translesion synthesis by polk 0.2319600582821689 0.0305625298387649 0.9756184250374108 1.0 1.0 9 P35249,P35250,P12004,P40937,P35251 5
Degradation of gli1 by the proteasome 0.2119085552186342 0.0303052771449377 0.9758235879542176 1.0 1.0 39 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 19
Fceri mediated nf kb activation 0.1878054102595522 0.0301082823267282 0.9759806953853168 1.0 1.0 41 Q15750,P20618,P28070,P25788,P43686,P35998,P62333,P07948,P25786,Q99460,O00231,O00487,Q13616,Q14997,O75832,Q99436,O00232,P25789,P49721,P49720,P48556 21
Rhobtb gtpase cycle 0.2063439454081688 0.0295454262794399 0.976429589807568 1.0 1.0 26 P78371,Q9NYL9,P62995,Q16643,Q9UM54,O43396,Q13098,Q8IYB3,Q9BT78,Q8N684,Q12792 11
Downstream signaling events of b cell receptor bcr 0.1728482437729407 0.0294894502259564 0.9764742327839272 1.0 1.0 40 P20618,P28070,Q14997,Q99436,P49721,Q13616 6
Hedgehog on state 0.1635844707226274 0.0294280148841356 0.9765232298298 1.0 1.0 40 P20618,P28070,P25788,P43686,P35998,P62333,P25786,Q99460,O00231,O00487,Q14997,O75832,P62195,Q99436,O00232,P25789,P49721,P49720,P48556 19
Interleukin 12 signaling 0.2024235935575701 0.0294222157783697 0.9765278548440685 1.0 1.0 24 Q53EL6,P07355,O14979,P52597,Q13126,Q99439 6
Transport of mature mrnas derived from intronless transcripts 0.1680213464505013 0.0285617745396448 0.9772140991357104 1.0 1.0 38 Q9NRG9,P37198,Q99567,Q6UN15,Q8NFH3 5
Global genome nucleotide excision repair gg ner 0.1797861220734989 0.0282988490315288 0.9774237985733398 1.0 1.0 37 Q9NR33,P35249,P35250,P18858,P28340,P12004,Q16531,Q9NRF9,P09874,P49916,P35251,P40937,Q13098,Q9Y2S7,P19447,Q9Y265,Q9BT78,Q07864 18
Sumoylation of chromatin organization proteins 0.160937133952197 0.0267355267418827 0.978670677010059 1.0 1.0 34 Q8NFH3,P37198,Q13547,Q99567 4
Sumoylation of rna binding proteins 0.162284197424202 0.0259010958600171 0.9793362259711248 1.0 1.0 32 Q8NFH3,Q9NRG9,P37198,Q99567 4
Regulation of glucokinase by glucokinase regulatory protein 0.1651858216834776 0.0244193472319851 0.9805181160671932 1.0 1.0 28 Q8NFH3,P37198,Q99567 3
Sumoylation of sumoylation proteins 0.1651858216834776 0.0244193472319851 0.9805181160671932 1.0 1.0 28 Q8NFH3,P37198,Q99567 3
Sumoylation of ubiquitinylation proteins 0.1651858216834776 0.0244193472319851 0.9805181160671932 1.0 1.0 28 Q8NFH3,P37198,Q99567 3
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.2312204775174413 0.0219622797236712 0.9824780446948124 1.0 1.0 8 P30260,Q9H1A4 2
Hdl clearance 0.4262555626191909 0.0206714477184385 0.9835077455718176 1.0 1.0 2 Q00341 1
G protein mediated events 0.229538599820056 0.0203847722511562 0.9837364313108012 1.0 1.0 8 P28482 1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4148124602669978 0.0194779464645231 0.984459829877914 1.0 1.0 2 Q13555 1
Camk iv mediated phosphorylation of creb 0.4148124602669978 0.0194779464645231 0.984459829877914 1.0 1.0 2 Q13555 1
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2192682706209143 0.0189103164748381 0.9849126496564438 1.0 1.0 9 P30260,Q9H1A4 2
Acyl chain remodelling of pg 0.3970120788302542 0.0181043342333071 0.985555620300909 1.0 1.0 2 Q92604 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.3544183089637626 0.0164202211542471 0.98689914777533 1.0 1.0 2 Q9UBE0 1
Processing and activation of sumo 0.3544183089637626 0.0164202211542471 0.98689914777533 1.0 1.0 2 Q9UBE0 1
Sumo is conjugated to e1 uba2 sae1 0.3544183089637626 0.0164202211542471 0.98689914777533 1.0 1.0 2 Q9UBE0 1
Met interacts with tns proteins 0.3235855054036868 0.0159774219378684 0.9872524040801394 1.0 1.0 2 P05556 1
Vitamin d calciferol metabolism 0.2685950413223178 0.0157668314938296 0.9874204097800792 1.0 1.0 2 P38435 1