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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:726b815fe10f1ee50040a1d21c1eed79bce22956ed817e076a9fd1d20cba7f43
+size 70849

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.6
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C292/C292_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+L-lactate dehydrogenase, active site [IPR018177]	0.5789993416721544	0.1563624380835076	0.8757473430188589	1.0	0.9998862636869636	2	P00338	1
+Nucleoside diphosphate kinase, active site [IPR023005]	0.4542462146148803	0.0457283552913946	0.963526763189256	1.0	0.9998862636869636	2	P15531	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDC34", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["LDHA", "NME1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:aadd1a5b9291c0722bf2bab6e3f92996f768fe882945d9a94d29b7c56879b7ed
+size 70233

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M16, zinc-binding site [IPR001431]	2	5	2.142410074043342	0.03216049794589	1.730582524271845	5.0	0.6776547957610433	0.4740055886775391	1.2118895823030245	0.0	0.8079860258854747	0.314626832259423	1.0	1.0	1.0	0.0056136137273067	0.0010694525645264

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.548387096774194
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C292/C292_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.8297153049895789	2.142410074043342	0.03216049794589	0.6370024821371711	0.1842354037128711	5	Q10713,O43847	2
+EF-Hand 1, calcium-binding site [IPR018247]	0.4562019596088597	1.5473862266868674	0.1217701404643858	0.9821411221962004	0.3431703958541782	40	P41208,Q96AY3,Q9BRK5,O95302,P0DP25,P80303,P19174,Q14257,Q9Y680,O43852,Q9NWM8,Q9BPX6,Q15293,P43304	14
+Beta tubulin, autoregulation binding site [IPR013838]	0.5997984867062016	1.1192278795919268	0.263042934435346	0.9999222486753092	0.5824522119639804	5	P04350,Q9BUF5	2
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.7518104015799878	0.5699112790402787	0.5687378744832097	0.9999999999952468	0.8998451545161533	2	P34896	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "LPCAT2", "MACF1", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TKT", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GPD2", "MICU1", "NRDC", "NUCB2", "PLCG1", "PMPCA", "RCN1", "RCN2", "SDF4", "SHMT1", "TUBB4A", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Thioredoxin, conserved site [IPR017937]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:8996bbb6c0d807f52bb417ab583862d37a2204705b3a77c68b8eb062a4c4cd8b
+size 77135

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Proteasome beta-type subunit, conserved site [IPR016050]	6	8	2.4302578529833587	0.0150880843375871	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0461123069087121	0.0479914252810258	0.0930016660897952	1.8654270901726772e-06	6.624514437802759e-08
+Syntaxin/epimorphin, conserved site [IPR006012]	4	8	2.15581900786742	0.0310978006552089	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	1.0	1.0	1.0	0.0033939033653995	0.0002504856541451
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	3	7	2.145558647367491	0.0319082076531631	2.813106796116505	7.288834951456311	-0.5861883336862886	0.343247888518411	1.6359205295141483	0.5883757483977968	1.1482455180262974	0.2604113174624136	0.0506073598520519	0.0526645480715484	0.1018169846714528	0.0020298329670106	0.0013990642028563

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 271,
+    "title": "Average number of proteins per term",
+    "value": 2.5830258302583027
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C292/C292_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.8700807801975035	2.4302578529833587	0.0150880843375871	0.9837559940233366	0.5089168459779094	8	P49721,P28072,P49720,P20618,P28070,P28074	6
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8075912554401563	2.15581900786742	0.0310978006552089	0.999808634251648	0.5089168459779094	8	P56962,O43752,O60499,Q13190	4
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.8089558857109067	2.145558647367491	0.0319082076531631	0.9998474606719818	0.5089168459779094	7	P49419,O94788,P51648	3
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.6730873816599214	1.5281793326665298	0.126468018684061	1.0	0.576096211666052	7	O94788,P51648	2
+14-3-3 protein, conserved site [IPR023409]	0.6699757862069813	1.5054502597854968	0.1322083557482931	1.0	0.5859360379899116	6	Q04917,P62258,P31946,P61981	4
+Haem oxygenase conserved site [IPR018207]	0.9605003291639176	1.3103648672390271	0.1900724328640606	1.0	0.6544270007701422	2	P30519	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.930546412113223	1.198026320015543	0.2309067706436713	1.0	0.7192613200509764	2	Q16836	1
+Guanylate kinase, conserved site [IPR020590]	0.6151987275423005	1.1890568802199568	0.2344172848204457	1.0	0.7207607206544339	5	O14936,Q5T2T1,Q00013	3
+Tubulin, conserved site [IPR017975]	0.5997984867062016	1.1192278795919268	0.263042934435346	1.0	0.7583471833189229	5	P04350,Q9BUF5	2
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.540429264194646	0.9044114613414452	0.3657772629912632	1.0	0.8366545492192743	6	Q8NEB9,P42356,P42345,Q9UBF8	4
+Tetraspanin, conserved site [IPR018503]	0.8334430546411871	0.8435332457639539	0.3989302803642851	1.0	0.8524392909986046	2	O43657	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.7820934825543129	0.6675883128868324	0.5043964199459874	1.0	0.949246040315018	2	O00429	1
+Intermediate filament protein, conserved site [IPR018039]	0.4567873252048882	0.5295243812957368	0.5964417356486964	1.0	0.98821577745302	8	P08670,P07197,P07196	3
+Thioredoxin, conserved site [IPR017937]	0.4481388206571334	0.4927510428848946	0.6221885067801258	1.0	1.0	12	Q96JJ7,Q9H1E5,O43396,Q14554,P07237	5
+Sterol reductase, conserved site [IPR018083]	0.7077024358130082	0.4384086274270993	0.6610900934893649	1.0	1.0	2	Q14739	1
+S100/Calbindin-D9k, conserved site [IPR001751]	0.6849901250822923	0.3766886441827588	0.7064050029169913	1.0	1.0	2	P31949	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.6405529953917066	0.2698794408267739	0.7872530043380859	1.0	1.0	2	P14174	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.5918367346938793	0.1765806496192846	0.8598377945898337	1.0	1.0	2	Q9GZZ9	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.3717484359565426	0.0818532488864216	0.9347634116096236	1.0	1.0	3	Q9Y2T2,Q96CW1	2
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.5131665569453607	0.0803779725048338	0.9359366456066164	1.0	1.0	2	P01889	1
+Sugar transporter, conserved site [IPR005829]	0.4904542462146169	0.0638645410750851	0.9490780867388802	1.0	1.0	2	P11166	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.3212263387178103	0.057480883117474	0.9541621339896168	1.0	1.0	10	Q9UBS8	1
+Ribosomal protein S2, conserved site [IPR018130]	0.4693877551020428	0.0522187999103803	0.958354353206937	1.0	1.0	2	Q9Y399	1
+Ribosomal protein L3, conserved site [IPR019926]	0.468729427254775	0.051905908170107	0.9586036665850812	1.0	1.0	2	P09001	1
+Actin/actin-like conserved site [IPR020902]	0.2406980572933911	0.0227276910554957	0.9818674872695784	1.0	1.0	3	P61160,P61163	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 14-18kDa subunit, conserved site [IPR020708]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycerate/sugar phosphate transporter, conserved site [IPR021159]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "PTR2 family proton/oligopeptide symporter, conserved site [IPR018456]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BRD2", "BRPF1", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CHD5", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NTHL1", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIK3C3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR2F", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP8", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC15A4", "SLC1A5", "SLC27A4", "SLC2A1", "SLC37A4", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX17", "STX18", "STX3", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN6", "TUBB", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTR1A", "ACTR2", "ALDH1A2", "ALDH3A2", "ALDH7A1", "AP2M1", "AP3M1", "CASK", "DNM1L", "HADH", "HLA-B", "HMOX2", "LBR", "MIF", "MPP1", "MPP7", "MRPL3", "MRPS2", "MTOR", "NEFL", "NEFM", "P4HB", "PDIA5", "PI4KA", "PI4KB", "PIK3C3", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "RNF14", "S100A11", "SLC2A1", "STX10", "STX17", "STX5", "STX6", "TMX3", "TMX4", "TSPAN6", "TUBB4A", "TUBB6", "TXNL1", "UBA5", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAH"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Target SNARE coiled-coil homology domain [IPR000727]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "EF-hand domain [IPR002048]", "2": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "3": "Importin-beta, N-terminal domain [IPR001494]", "4": "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "5": "Proteasome component (PCI) domain [IPR000717]", "6": "FERM, N-terminal [IPR018979]", "7": "FERM, C-terminal PH-like domain [IPR018980]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a0f0af70359f8c63a289bdfcbfeb74b3ef1b99c910ede0f9c01b62dfbe4d1f0a
+size 142587

interpro_domain/df_merge.tsv

@@ -0,0 +1,6 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	6	2.2600480771269984	0.0238182671469013	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0550816697898294	0.0015075035399645	0.0001833288791406	0.0001450038876457	0.000160552482799
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	3	5	2.1510640499874376	0.0314711445562494	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0370595951599339	0.0385773062479974	0.075113296023457	0.014977467250991	0.0053637976870067
+Aminopeptidase N-like , N-terminal domain [IPR045357]	3	5	2.1510640499874376	0.0314711445562494	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	0.0370595951599339	0.0385773062479974	0.075113296023457	0.014977467250991	0.0053637976870067
+Target SNARE coiled-coil homology domain [IPR000727]	6	12	2.0465754532004925	0.0406997870360417	3.5024271844660193	8.266990291262136	0.5942034778060385	0.4012381903331891	1.9023475359698396	2.183694577914796	1.0582363712887182	0.3038263160802639	1.0	1.0	1.0	0.0002915955446555	0.0001398373652982
+Aldehyde dehydrogenase domain [IPR015590]	3	9	1.975860830468546	0.0481705415515094	3.2985436893203883	9.529126213592232	-0.5613485854973601	0.3657232034282902	1.9683657938952	0.6908740865654212	1.1218179525542225	0.2726859723953302	0.0639684350193291	0.066549445548378	0.1277572387780678	0.0042425564235442	0.0037759888499611

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3040,
+    "annotations_size": 2522,
+    "title": "Average number of proteins per term",
+    "value": 2.120539254559873
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C292/C292_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,180 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.83871789009596	2.2600480771269984	0.0238182671469013	1.0	0.6038480930279013	6	Q8WUJ1,O43169,Q9UMX5	3
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8317396511081183	2.1510640499874376	0.0314711445562494	1.0	0.6038480930279013	5	Q9NZ08,P55786,P09960	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8317396511081183	2.1510640499874376	0.0314711445562494	1.0	0.6038480930279013	5	Q9NZ08,P55786,P09960	3
+Target SNARE coiled-coil homology domain [IPR000727]	0.7665308757919305	2.0465754532004925	0.0406997870360417	1.0	0.6038480930279013	12	O43752,P56962,Q9UEU0,O15155,Q13190,O60499	6
+Aldehyde dehydrogenase domain [IPR015590]	0.7640786705993561	1.975860830468546	0.0481705415515094	1.0	0.6038480930279013	9	P49419,O94788,P51648	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8512681982929977	1.9457308009941396	0.0516870847420469	1.0	0.6038480930279013	4	Q96G23	1
+Peptidase M16, N-terminal [IPR011765]	0.7526615133178107	1.893947997286397	0.0582319127295627	1.0	0.6038480930279013	7	Q10713,Q5JRX3,O43847	3
+Peptidase M16, C-terminal [IPR007863]	0.7526615133178107	1.893947997286397	0.0582319127295627	1.0	0.6038480930279013	7	Q10713,Q5JRX3,O43847	3
+EF-hand domain [IPR002048]	0.4270212277724793	1.8489227645476392	0.0644689660483648	1.0	0.6138510800206655	46	P41208,Q9UJS0,Q96AY3,O95302,P0DP25,Q9BRK5,P80303,P19174,Q14257,Q9Y680,O43852,Q8IYU8,Q9NWM8,Q9BPX6,Q66K14,Q15293,P60660,P43304	18
+Intermediate filament head, DNA-binding domain [IPR006821]	0.82707509881423	1.8477635922428404	0.0646365499329084	1.0	0.6138510800206655	4	P07196,P08670,P07197	3
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.7032814078903299	1.6682103916697937	0.0952739687404007	1.0	0.6299593274454672	7	Q8N4Q0,Q8N8N7	2
+ERAP1-like C-terminal domain [IPR024571]	0.8732853568815028	1.659822083381178	0.0969502497923466	1.0	0.6299593274454672	3	P55786	1
+Reticulon [IPR003388]	0.871254527494232	1.6520176739102872	0.0985309479746603	1.0	0.6299593274454672	3	O95197,Q9NQC3	2
+FAD dependent oxidoreductase [IPR006076]	0.7737163006453549	1.628976093011032	0.1033180800229316	1.0	0.6299593274454672	4	Q8NCN5,Q96CU9	2
+Major facilitator superfamily domain [IPR020846]	0.6906093228109736	1.60960655136959	0.1074837770908017	1.0	0.6299593274454672	7	O43826,Q14728,P53985	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6849889120392589	1.5835353925143736	0.1132994864120173	1.0	0.6365819068725843	7	Q8NF37,Q86UL3,Q7L5N7,Q9NUQ2	4
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.6750330670099084	1.5721445564572043	0.1159170301811101	1.0	0.6383029478531871	10	Q96AY3,P62942,Q9Y680,P26885,Q9NWM8	5
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8452420151465171	1.5517917873010874	0.1207120516724633	1.0	0.6465780994488391	3	P52888,Q99797	2
+Importin-beta, N-terminal domain [IPR001494]	0.6544220743020748	1.5194299919867893	0.1286542974089046	1.0	0.6594840204578406	13	Q8TEX9,P55060,O00410,Q9UIA9,O95373,Q92973,Q9UI26,O43592,O15397,Q9HAV4,Q96P70	11
+14-3-3 domain [IPR023410]	0.6699757862069813	1.5054502597854968	0.1322083557482931	1.0	0.6603097803581536	6	Q04917,P62258,P31946,P61981	4
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.665612261739357	1.5028504625548913	0.1328776096960298	1.0	0.6603097803581536	8	P13674,Q32P28,O00469	3
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.665612261739357	1.5028504625548913	0.1328776096960298	1.0	0.6603097803581536	8	P13674,Q32P28,O00469	3
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.7378115323084784	1.4800370683027757	0.1388633544975201	1.0	0.6678698228710885	4	P13674,Q32P28	2
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.662258783078173	1.469809979627826	0.1416132255524207	1.0	0.6678698228710885	6	P98194,P16615,Q8NB49,Q9HD20	4
+Zinc finger, CHHC-type [IPR012996]	0.8228514981889986	1.4652067686041048	0.1428645134768285	1.0	0.6684680945984443	3	P55795,P52597	2
+Ataxin-2, C-terminal [IPR009818]	0.6658757046370998	1.418920207278622	0.1559222802949615	1.0	0.6862593992262582	5	Q9BPZ3	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.6420964235050338	1.391532330117901	0.1640640629095813	1.0	0.6991870981727305	8	Q7L5N1,O95630,Q92905	3
+Polyketide synthase, enoylreductase domain [IPR020843]	0.6415089443414228	1.3804624590585772	0.1674443007019515	1.0	0.7049992092993684	7	Q8N4Q0,Q14914	2
+BAG domain [IPR003103]	0.7101449275362399	1.364644879675096	0.1723646917801842	1.0	0.7092971793610695	4	O95817,O95429,Q9UL15	3
+YTH domain [IPR007275]	0.6525128279512984	1.3583954928077802	0.1743382236908293	1.0	0.7137678573835576	5	Q7Z739,Q9Y5A9,Q9BYJ9	3
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.9710335747202072	1.3500250201618242	0.1770079573767371	1.0	0.7169465128234217	2	Q9Y282	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.9710335747202072	1.3500250201618242	0.1770079573767371	1.0	0.7169465128234217	2	Q9Y282	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7899242673691163	1.3375843413648738	0.1810319716718229	1.0	0.7169465128234217	3	Q86UL3,Q7L5N7	2
+GMP phosphodiesterase, delta subunit [IPR008015]	0.9674127715602334	1.336384879427405	0.1814235059705631	1.0	0.7169465128234217	2	A6NIH7	1
+DNA2/NAM7 helicase-like, C-terminal [IPR041679]	0.7014823831863386	1.3284503437220307	0.1840293774893706	1.0	0.7184552477216607	4	Q9HCE1,P51530	2
+Tim10-like [IPR004217]	0.6988572159238224	1.3174784353472289	0.1876783048284025	1.0	0.7233206060147985	4	P62072	1
+Peptidase M48 [IPR001915]	0.9595128373930186	1.3066500985940408	0.1913315736101011	1.0	0.7240750570114829	2	O75844	1
+GRAM domain [IPR004182]	0.7800160873154462	1.2991671979547166	0.1938865559324374	1.0	0.725412825508426	3	Q66K14	1
+START domain [IPR002913]	0.9572086899275806	1.2979847963735	0.1942925594260882	1.0	0.725412825508426	2	Q9NQZ5	1
+Rab-GTPase-TBC domain [IPR000195]	0.6388760345485609	1.2965359536984178	0.1947909015457192	1.0	0.725412825508426	5	Q8TC07	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.930546412113223	1.198026320015543	0.2309067706436713	1.0	0.7590593750476877	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.930546412113223	1.198026320015543	0.2309067706436713	1.0	0.7590593750476877	2	Q16836	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.6024680545175383	1.196768069289965	0.2313969671663551	1.0	0.7590593750476877	7	Q9H7Z7,P78417	2
+Oxidoreductase, N-terminal domain [IPR041694]	0.920671494404206	1.1611876085958222	0.2455656128613128	1.0	0.7713546633325251	2	Q8N8N7	1
+Syntaxin 6, N-terminal [IPR015260]	0.9200131665569397	1.15873594648448	0.2465638337243973	1.0	0.7713546633325251	2	O43752	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6060766410667671	1.147678908338381	0.2511011413584354	1.0	0.7713546633325251	5	Q03518,P08183	2
+FCP1 homology domain [IPR004274]	0.7408626934474734	1.1476740115579425	0.2511031635987324	1.0	0.7713546633325251	3	Q3ZCQ8,Q9Y5B0	2
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.5997984867062016	1.1192278795919268	0.263042934435346	1.0	0.7822203685852159	5	P04350,Q9BUF5	2
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.5997984867062016	1.1192278795919268	0.263042934435346	1.0	0.7822203685852159	5	P04350,Q9BUF5	2
+CBS domain [IPR000644]	0.5955690145383417	1.1000776614455496	0.2712982859081143	1.0	0.7843394270878244	5	P51798	1
+Peptidase S9A, N-terminal domain [IPR023302]	0.8940092165898619	1.062400532064148	0.2880538923587077	1.0	0.7967236812902623	2	P48147	1
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.5686077843865636	1.0374622346587117	0.2995204872321972	1.0	0.8081787787384782	7	Q8NEB9,Q9BTU6,P42356,P42345,Q9UBF8	5
+Exportin-2, central domain [IPR013713]	0.7115574580177816	1.0350915545303296	0.3006261563094412	1.0	0.8082933541710136	3	P55060,O15397	2
+EB1, C-terminal [IPR004953]	0.8821593153390336	1.0188867346746138	0.3082567420788806	1.0	0.8121035327417924	2	Q15555	1
+Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]	0.6218708827404552	0.9968174295992582	0.3188531364522053	1.0	0.8222597403596797	4	Q8NEB9,P42356,Q9UBF8	3
+Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]	0.5653771243641779	0.9640041422313294	0.3350438491448062	1.0	0.8399409418918502	5	O00743,P62140	2
+Sec63 domain [IPR004179]	0.6917276877476999	0.9596166372421022	0.337248192574608	1.0	0.8437896246757554	3	O75643	1
+MPN domain [IPR037518]	0.5482204833130918	0.955531052836244	0.3393092095425229	1.0	0.8481048825235311	10	O95630	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.6878132329841031	0.9448062344884226	0.344757808389422	1.0	0.8520177283761676	3	P48147	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.6080368906455963	0.9399062462026928	0.3472656531118117	1.0	0.8522308058095208	4	P98194,P16615,P20020	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.6080368906455963	0.9399062462026928	0.3472656531118117	1.0	0.8522308058095208	4	P98194,P16615,P20020	3
+Rpn11/EIF3F, C-terminal [IPR024969]	0.5954871647122321	0.8886414063150407	0.3741958304717407	1.0	0.869518788625927	4	Q7L5N1	1
+Glutathione S-transferase, C-terminal-like [IPR010987]	0.5293693705641764	0.8706960436495779	0.3839201392841684	1.0	0.8773439407403059	11	Q8TB36,Q9H7Z7,P78417	3
+DNA2/NAM7 helicase, helicase domain [IPR041677]	0.6675051479646824	0.8685452755896453	0.3850958979003716	1.0	0.8773439407403059	3	P51530	1
+Dynamin, GTPase domain [IPR001401]	0.667434968719121	0.8682835935645261	0.3852391014373337	1.0	0.8773439407403059	3	O00429,P50570	2
+Rhodanese-like domain [IPR001763]	0.6655676553520032	0.8613259548696208	0.3890585445840788	1.0	0.8807950174515681	3	Q8NCN5	1
+L27 domain [IPR004172]	0.5875924982147378	0.8566044464881276	0.3916635274993179	1.0	0.8811636305008512	4	O14936,Q5T2T1	2
+L27 domain, C-terminal [IPR014775]	0.5875924982147378	0.8566044464881276	0.3916635274993179	1.0	0.8811636305008512	4	O14936,Q5T2T1	2
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8285055957866803	0.8261557644425854	0.4087157378319475	1.0	0.8932245154351574	2	O15254	1
+TGS [IPR004095]	0.5175101466772785	0.7999622395852591	0.423732675243595	1.0	0.9121385687468948	6	Q9NTK5	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8169848584594939	0.7859518870809498	0.4318956746849247	1.0	0.922303887853836	2	P13674	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6344347350381834	0.7469868560348097	0.4550714949496688	1.0	0.9369649829449443	3	Q9UL46	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6344347350381834	0.7469868560348097	0.4550714949496688	1.0	0.9369649829449443	3	Q9UL46	1
+CAP Gly-rich domain [IPR000938]	0.5591792100288727	0.7430202879052115	0.457469397611502	1.0	0.9374904060329806	4	Q15813	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.7988808426596337	0.7238473772094762	0.4691594394914309	1.0	0.9374904060329806	2	Q14011	1
+Armadillo repeat-containing domain [IPR006911]	0.6232916340104135	0.7069583205294698	0.4795923794600112	1.0	0.9374904060329806	3	Q9UH62	1
+Fatty acid desaturase domain [IPR005804]	0.7906517445687962	0.6960985210265942	0.4863671326835357	1.0	0.9374904060329806	2	O15121	1
+G-protein gamma-like domain [IPR015898]	0.7853851217906526	0.6785102695166438	0.4974482147075005	1.0	0.9392009920668688	2	Q9UBI6	1
+Dynamin GTPase effector [IPR003130]	0.7820934825543129	0.6675883128868324	0.5043964199459874	1.0	0.942287237854652	2	O00429	1
+Dynamin stalk domain [IPR000375]	0.7820934825543129	0.6675883128868324	0.5043964199459874	1.0	0.942287237854652	2	O00429	1
+GTPase effector domain [IPR020850]	0.7820934825543129	0.6675883128868324	0.5043964199459874	1.0	0.942287237854652	2	O00429	1
+Glutathione S-transferase, C-terminal [IPR004046]	0.4864842839943072	0.660528973155533	0.5089144319299943	1.0	0.946981610594991	9	Q13155,P78417	2
+Syntaxin, N-terminal domain [IPR006011]	0.6094830424761217	0.6581443213732379	0.5104453984014319	1.0	0.946981610594991	3	Q13277,Q86Y82	2
+CARG-binding factor, N-terminal [IPR012956]	0.7554312047399533	0.5813047216551848	0.5610350989228066	1.0	0.988695749243334	2	Q99729	1
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.7518104015799878	0.5699112790402787	0.5687378744832097	1.0	0.988695749243334	2	P34896	1
+Nucleotidyl transferase domain [IPR005835]	0.7491770901909021	0.561677455747643	0.5743357970357723	1.0	0.988695749243334	2	Q9Y5P6	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7465437788018441	0.5534885309397505	0.5799289319239074	1.0	0.988695749243334	2	O60506	1
+VHS domain [IPR002014]	0.5058303500832262	0.5403692593226906	0.5889424033012292	1.0	0.988695749243334	4	O14964,O60784	2
+Intermediate filament, rod domain [IPR039008]	0.4567873252048882	0.5295243812957368	0.5964417356486964	1.0	0.988695749243334	8	P08670,P07197,P07196	3
+Agenet-like domain [IPR008395]	0.5677989455148389	0.5172984624333651	0.6049478272209621	1.0	0.988695749243334	3	Q06787	1
+Fxr1, tudor domain [IPR041560]	0.5677989455148389	0.5172984624333651	0.6049478272209621	1.0	0.988695749243334	3	Q06787	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.5677989455148389	0.5172984624333651	0.6049478272209621	1.0	0.988695749243334	3	Q06787	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.5677989455148389	0.5172984624333651	0.6049478272209621	1.0	0.988695749243334	3	Q06787	1
+Ubiquitin conjugation factor E4, core [IPR019474]	0.7175773535220552	0.4665901495181471	0.6407931359156365	1.0	0.988695749243334	2	Q14139	1
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.6948650427912932	0.4029735189816754	0.6869677054531156	1.0	0.988695749243334	2	P16435	1
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.6948650427912932	0.4029735189816754	0.6869677054531156	1.0	0.988695749243334	2	P16435	1
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.6948650427912932	0.4029735189816754	0.6869677054531156	1.0	0.988695749243334	2	P16435	1
+S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]	0.6849901250822923	0.3766886441827588	0.7064050029169913	1.0	0.988695749243334	2	P31949	1
+CTP synthase, N-terminal [IPR017456]	0.6823568136932205	0.3698276861784974	0.7115108849403986	1.0	0.988695749243334	2	P17812	1
+CTP synthase GATase domain [IPR033828]	0.6823568136932205	0.3698276861784974	0.7115108849403986	1.0	0.988695749243334	2	P17812	1
+U-box domain [IPR003613]	0.4127177501238324	0.3604711344017921	0.718494839155166	1.0	0.988695749243334	6	Q14139,P19474	2
+Class II aldolase/adducin N-terminal [IPR001303]	0.6777485187623449	0.3579749243976773	0.7203620791687317	1.0	0.988695749243334	2	Q9UEY8	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.5133355284820447	0.3530066644709582	0.7240834442557094	1.0	0.988695749243334	3	P10321,P01889	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.5133355284820447	0.3530066644709582	0.7240834442557094	1.0	0.988695749243334	3	P10321,P01889	2
+Immunoglobulin C1-set [IPR003597]	0.5133355284820447	0.3530066644709582	0.7240834442557094	1.0	0.988695749243334	3	P10321,P01889	2
+MHC class I-like antigen recognition-like [IPR011161]	0.5133355284820447	0.3530066644709582	0.7240834442557094	1.0	0.988695749243334	3	P10321,P01889	2
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.670836076366008	0.3405699978162321	0.7334273188227824	1.0	0.988695749243334	2	Q7L576	1
+GAT domain [IPR004152]	0.669519420671491	0.3373065210215908	0.7358858443995453	1.0	0.988695749243334	2	O60784	1
+Thioredoxin-like fold [IPR012336]	0.6609611586570122	0.3165057344370254	0.7516186732752366	1.0	0.988695749243334	2	Q6DKJ4	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.6579986833443069	0.3094741979567117	0.7569608365150915	1.0	0.988695749243334	2	Q5T9A4	1
+Aminotransferase, class I/classII [IPR004839]	0.3898937359244541	0.2793858216388046	0.7799487507453979	1.0	0.988695749243334	6	O15269,Q6YP21	2
+Proteasome component (PCI) domain [IPR000717]	0.3932855009084733	0.2727249287505721	0.7850646704946838	1.0	0.988695749243334	18	Q96PV6,P61201,Q7L2H7,P48556,Q9UNS2,Q9Y262,P60228,Q9BT78,O00231	9
+C2 phosphatidylinositol 3-kinase-type domain [IPR002420]	0.6214614878209361	0.2302226842850807	0.8179187357281215	1.0	0.988695749243334	2	Q8NEB9	1
+Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]	0.3949305784575346	0.2014254889880029	0.8403658862972023	1.0	0.988695749243334	4	Q13162,P30041	2
+Peroxiredoxin, C-terminal [IPR019479]	0.3949305784575346	0.2014254889880029	0.8403658862972023	1.0	0.988695749243334	4	Q13162,P30041	2
+Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]	0.3620708808001524	0.1842161260420656	0.853843909219623	1.0	0.988695749243334	7	O00743,P62140	2
+Exoribonuclease, phosphorolytic domain 1 [IPR001247]	0.3565074135090649	0.1711368820845122	0.8641161359309912	1.0	0.988695749243334	5	Q9NQT4,Q5RKV6,Q06265,Q8TCS8	4
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.5803159973666904	0.1583519600494263	0.8741794663963418	1.0	0.988695749243334	2	Q13098	1
+Mu homology domain [IPR028565]	0.3718708827404535	0.1513999126430448	0.8796602583690258	1.0	0.988695749243334	4	P48444,Q9Y2T2,Q96CW1	3
+Far upstream element-binding protein, C-terminal [IPR015096]	0.5710994075049391	0.144827004866243	0.8848474602073648	1.0	0.988695749243334	2	Q96AE4	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.3478588534337136	0.1370295867770951	0.8910074088283058	1.0	0.988695749243334	8	Q99956	1
+Glutamine amidotransferase [IPR017926]	0.3639657444005332	0.136151378973557	0.8917016111027214	1.0	0.988695749243334	4	P27708,P17812,Q9NRF8	3
+Exoribonuclease, phosphorolytic domain 2 [IPR015847]	0.3563899868247711	0.1224594600169288	0.9025351505095092	1.0	0.988695749243334	4	Q9NQT4,Q06265,Q8TCS8	3
+Protein kinase, C-terminal [IPR017892]	0.333349480787075	0.1177635617580508	0.9062550020948728	1.0	0.988695749243334	5	Q05655	1
+BRO1 domain [IPR004328]	0.4007243990780332	0.1166686985930164	0.9071225957436808	1.0	0.988695749243334	3	Q8WUM4,Q9H3S7	2
+BAP29/BAP31, transmembrane domain [IPR040463]	0.5339038841343007	0.0995367574642257	0.9207121045606196	1.0	0.9920652758388806	2	P51572	1
+Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]	0.5339038841343007	0.0995367574642257	0.9207121045606196	1.0	0.9920652758388806	2	P51572	1
+FERM, N-terminal [IPR018979]	0.3267392021101168	0.0914715441767493	0.9271179158839478	1.0	0.9928296068073116	7	P15311,P11171,Q9Y2J2,P26038,Q9HCM4,P35241	6
+FERM, C-terminal PH-like domain [IPR018980]	0.3267392021101168	0.0914715441767493	0.9271179158839478	1.0	0.9928296068073116	7	P15311,P11171,Q9Y2J2,P26038,Q9HCM4,P35241	6
+ENTH  domain [IPR013809]	0.5161290322580665	0.082865847363366	0.9339582104670412	1.0	0.9928296068073116	2	Q14677	1
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.3290956000659738	0.0823801652380719	0.9343444082787382	1.0	0.9928296068073116	9	O15254,Q9H845	2
+CS domain [IPR007052]	0.3276129215616311	0.0788851488044526	0.9371239759640326	1.0	0.9928296068073116	9	Q9P035,O94966	2
+FERM adjacent (FA) [IPR014847]	0.3264163372859053	0.0770496976592305	0.9385840094269904	1.0	0.9928296068073116	4	P11171,Q9HCM4,Q9Y2J2	3
+Small-subunit processome, Utp12 [IPR007148]	0.3598946328613746	0.0705069693431605	0.943790153623713	1.0	0.9928296068073116	3	Q15269,Q9UNX4	2
+Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]	0.4947333772218587	0.0666437317481948	0.9468653302103572	1.0	0.9928296068073116	2	Q13557	1
+ALIX V-shaped domain [IPR025304]	0.4921000658327867	0.0649160196857502	0.9482408656327987	1.0	0.9928296068073116	2	Q9H3S7	1
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.4835418038183036	0.059680349326314	0.952410222799322	1.0	0.9928296068073116	2	Q9UJY4	1
+PIK-related kinase, FAT [IPR003151]	0.4795918367346959	0.0574526800861628	0.954184599626616	1.0	0.9928296068073116	2	P42345	1
+PIK-related kinase [IPR014009]	0.4795918367346959	0.0574526800861628	0.954184599626616	1.0	0.9928296068073116	2	P42345	1
+FATC domain [IPR003152]	0.4795918367346959	0.0574526800861628	0.954184599626616	1.0	0.9928296068073116	2	P42345	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.4792626728110619	0.0572722538232365	0.9543283223050234	1.0	0.9928296068073116	2	P51114	1
+Zinc finger, ZZ-type [IPR000433]	0.478604344963794	0.0569137768231245	0.954613879784474	1.0	0.9928296068073116	2	Q86YT6	1
+EF hand associated, type-2 [IPR013567]	0.4776168531928921	0.0563819696148371	0.9550375202674616	1.0	0.9928296068073116	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.4776168531928921	0.0563819696148371	0.9550375202674616	1.0	0.9928296068073116	2	Q8IXI2	1
+EF hand associated, type-1 [IPR013566]	0.4776168531928921	0.0563819696148371	0.9550375202674616	1.0	0.9928296068073116	2	Q8IXI2	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]	0.4588545095457561	0.0475520800593711	0.9620732233648132	1.0	0.9970902860519554	2	Q9UDR5	1
+Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]	0.4588545095457561	0.0475520800593711	0.9620732233648132	1.0	0.9970902860519554	2	Q9UDR5	1
+Nucleoside diphosphate kinase-like domain [IPR034907]	0.4542462146148803	0.0457283552913946	0.963526763189256	1.0	0.9970902860519554	2	P15531	1
+Zinc finger, RING-type [IPR001841]	0.3309346993445168	0.043729067487786	0.9651203688679436	1.0	0.9970902860519554	21	O94822,Q9UBS8	2
+Copine, C-terminal [IPR010734]	0.3194040424255606	0.0428148109656204	0.9658491573728076	1.0	0.9970902860519554	3	Q86YQ8	1
+Copine, C2B domain [IPR037768]	0.3194040424255606	0.0428148109656204	0.9658491573728076	1.0	0.9970902860519554	3	Q86YQ8	1
+CSN8/PSMD8/EIF3K [IPR033464]	0.3161014158709317	0.0412170577589467	0.9671228551027344	1.0	0.9970902860519554	3	Q99627,P48556	2
+Extended synaptotagmin, C2A domain [IPR037733]	0.439104674127718	0.0405825967334846	0.9676286585210014	1.0	0.9970902860519554	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.439104674127718	0.0405825967334846	0.9676286585210014	1.0	0.9970902860519554	2	A0FGR8	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.439104674127718	0.0405825967334846	0.9676286585210014	1.0	0.9970902860519554	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.439104674127718	0.0405825967334846	0.9676286585210014	1.0	0.9970902860519554	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.439104674127718	0.0405825967334846	0.9676286585210014	1.0	0.9970902860519554	2	A0FGR8	1
+PIN domain [IPR002716]	0.437458854509548	0.0400958201260516	0.9680167341799236	1.0	0.9970902860519554	2	Q9Y2L1	1
+3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]	0.4312047399605027	0.0383650663202301	0.969396613503158	1.0	0.9970902860519554	2	Q49A26	1
+Fzo/mitofusin HR2 domain [IPR006884]	0.4292297564186989	0.0378561728715487	0.969802356962742	1.0	0.9970902860519554	2	O95140	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.4028966425279811	0.0325694433133469	0.9740179376003472	1.0	0.9970902860519554	2	Q93009	1
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.4015799868334455	0.0323691629566381	0.9741776539913832	1.0	0.9970902860519554	2	O75694	1
+MRG domain [IPR026541]	0.3959842001316681	0.0315757512922649	0.974810381410488	1.0	0.9970902860519554	2	Q9UBU8	1
+Core histone macro-H2A, macro domain [IPR035796]	0.395655036208034	0.0315318872634509	0.974845362423206	1.0	0.9970902860519554	2	O75367	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.2956290337403233	0.030329598835641	0.9758041909691028	1.0	0.9970902860519554	7	O14936,Q5T2T1,Q00013	3
+Guanylate kinase-like domain [IPR008144]	0.2956290337403233	0.030329598835641	0.9758041909691028	1.0	0.9970902860519554	7	O14936,Q5T2T1,Q00013	3
+Aminopeptidase P, N-terminal [IPR007865]	0.3238973008558289	0.0269154848322899	0.9785271428817536	1.0	0.9970902860519554	2	Q9NQH7	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]	0.322580645161293	0.0268880007761179	0.9785490640521886	1.0	0.9970902860519554	2	Q96G03	1
+Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]	0.322580645161293	0.0268880007761179	0.9785490640521886	1.0	0.9970902860519554	2	Q96G03	1
+RBM1CTR [IPR012604]	0.3071099407504966	0.0266379531808827	0.978748501730272	1.0	0.9970902860519554	2	P38159	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.3011849901250851	0.0265712727574541	0.9788016861851696	1.0	0.9970902860519554	2	Q99707	1
+FDF domain [IPR019050]	0.2952600394996737	0.0265169809174471	0.9788449895478232	1.0	0.9970902860519554	2	Q9BX40	1
+DFDF domain [IPR025762]	0.2952600394996737	0.0265169809174471	0.9788449895478232	1.0	0.9970902860519554	2	Q9BX40	1
+Lsm14-like, N-terminal [IPR025609]	0.2952600394996737	0.0265169809174471	0.9788449895478232	1.0	0.9970902860519554	2	Q9BX40	1
+Coatomer, WD associated region [IPR006692]	0.2843976300197526	0.0264431652407659	0.9789038652912933	1.0	0.9970902860519554	2	P35606	1
+Dynamin, N-terminal [IPR045063]	0.289471454334492	0.020518633808345	0.983629647575782	1.0	1.0	7	O00429	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.289471454334492	0.020518633808345	0.983629647575782	1.0	1.0	7	O00429	1
+FAD/NAD(P)-binding domain [IPR023753]	0.2662339767105782	0.0183813312773082	0.9853346454102048	1.0	1.0	5	O95831	1
+Heat shock chaperonin-binding [IPR006636]	0.2486824769433506	0.0162382465479437	0.9870443231476048	1.0	1.0	4	Q9NRR5,P54727,Q9UHD9	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]", "2": "Ezrin/radixin/moesin-like [IPR000798]", "3": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}